title: Acute Onset Anti-Synthetase Syndrome With Pericardial Effusion and Non-Specific Interstitial Pneumonia.
abstract: Anti-synthetase syndrome (AS) is a clinical entity which is described classically by the triad of interstitial lung disease (ILD), inflammatory myositis and presence of aminoacyl-tRNA synthetase antibodies (ASA). We describe a rare presentation of this condition with regard to the uncharacteristically acute nature of presentation, acute decompensation in clinical condition, development of acute interstitial pneumonitis requiring rescue extracorporeal membrane oxygenation (ECMO) and accompaniment of significant pericardial effusion on presentation, followed by rapid improvement with initiation of steroids.
authors.affiliation: Advocate Christ Medical Center, 4440 W 95th Street, Oak Lawn, IL 60453, USA.
authors.forename: Aditya
authors.initials: A
authors.lastname: Shah
authors.affiliation: Advocate Christ Medical Center, 4440 W 95th Street, Oak Lawn, IL 60453, USA.
authors.forename: Samir R
authors.initials: SR
authors.lastname: Patel
keywords: Anti-synthetase syndrome; ECMO; Pericardial effusion