title: Infective Endocarditis of the Aortic Valve with Anterior Mitral Valve Leaflet Aneurysm.
abstract: Mitral valve leaflet aneurysm is a rare and potentially devastating complication of aortic valve endocarditis. We report the case of a 48-year-old man who had endocarditis of the native aortic valve and a concomitant aneurysm of the anterior mitral valve leaflet. Severe mitral regurgitation occurred after the aneurysm perforated. The patient showed no signs of heart failure and completed a 6-week regimen of antibiotic therapy before undergoing successful aortic and mitral valve replacement. In addition to the patient's case, we review the relevant medical literature.
authors.forename: Anton
authors.initials: A
authors.lastname: Tomsic
authors.forename: Wilson W L
authors.initials: WW
authors.lastname: Li
authors.forename: Marieke
authors.initials: M
authors.lastname: van Paridon
authors.forename: Navin R
authors.initials: NR
authors.lastname: Bindraban
authors.forename: Bas A J M
authors.initials: BA
authors.lastname: de Mol
mesh_terms: D000328:Adult; D000368:Aged; D000785:Aneurysm, Infected / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D004334:Drug Administration Schedule; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006322:Heart Aneurysm / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D006349:Heart Valve Diseases / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D013290:Streptococcal Infections / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D054773:Streptococcus gordonii / Q000187:drug effects / Q000302:isolation & purification*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents
keywords: Aneurysm, infected/etiology; endocarditis, bacterial/complications/diagnosis; heart aneurysm/microbiology/surgery; heart valve diseases/diagnosis/etiology; heart valve prosthesis implantation; mitral valve/microbiology/pathology/surgery; rare diseases; streptococcal infections/complications/diagnosis; treatment outcome