title: Ruthenium(0)-Catalyzed C-H Arylation of Aromatic Imines under Neutral Conditions: Access to Biaryl Aldehydes.
abstract: The first ruthenium(0)-catalyzed C-H bond arylation of aromatic imines with arylboronates under neutral conditions is reported. This versatile method provides rapid access to a wide range of biaryl aldehydes that are difficult to assemble using traditional methods with high atom economy. A new hydrogen acceptor for Ru(0) arylation has been identified. This atom-economical strategy has potential for an array of direct applications in Ru(0)-catalyzed C-H bond arylations using removable directing groups. An indole synthesis by a sequential one-pot, multiple C-H activation protocol is reported.
authors.affiliation: Department of Chemistry, Rutgers University , 73 Warren Street, Newark, New Jersey 07102, United States.
authors.forename: Feng
authors.initials: F
authors.lastname: Hu
authors.affiliation: Department of Chemistry, Rutgers University , 73 Warren Street, Newark, New Jersey 07102, United States.
authors.forename: Michal
authors.initials: M
authors.lastname: Szostak