title: Validation of the Medication Adherence Rating Scale in homeless patients with schizophrenia: Results from the French Housing First experience.
abstract: The Medication Adherence Rating Scale (MARS) is one of the most widely used measurements of adherence in schizophrenia (SZ), but there is no available data regarding its psychometric properties in homeless SZ patients (HSZ). The aim of this study was therefore to assess the psychometric properties of the MARS in a large multicenter sample of HSZ subjects. This multi-centre prospective study was conducted in the following 4 French cities: Lille, Marseille, Paris and Toulouse. Three hundred and fifty-three patients were included. The 3-factor structure of the MARS was confirmed using confirmatory factor analysis: RMSEA = 0.045, CFI = 0.98, TLI = 0.97 and WRMR = 0.76. The unidimensionality of each factor was supported by the satisfactory INFIT statistics. Item internal consistencies were all higher than 0.20 and the Kuder-Richardson were higher than to 0.6, except for factor 2, which was closed to 0.5. Significant associations with symptoms, functioning and quality of life showed satisfactory external validity. The acceptability was satisfactory with missing data lower than 5% for each dimension. The MARS is a short self-administered instrument with acceptable psychometric properties in homeless SZ patients that yields interesting information about medication adherence.
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.|Department of Psychiatry, Sainte-Marguerite University Hospital, Marseille, France.
authors.forename: K
authors.initials: K
authors.lastname: Zemmour
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.|Department of Psychiatry, Sainte-Marguerite University Hospital, Marseille, France.
authors.forename: A
authors.initials: A
authors.lastname: Tinland
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.
authors.forename: M
authors.initials: M
authors.lastname: Boucekine
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.|Department of Psychiatry, Sainte-Marguerite University Hospital, Marseille, France.
authors.forename: V
authors.initials: V
authors.lastname: Girard
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.
authors.forename: S
authors.initials: S
authors.lastname: Loubière
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.
authors.forename: N
authors.initials: N
authors.lastname: Resseguier
authors.affiliation: Université Paris-Est Créteil, Pôle de psychiatrie des hôpitaux universitaires H Mondor, INSERM U955, Eq Psychiatrie Génétique, Fondation FondaMental Fondation de coopération scientifique en santé mentale, Pole de Psychiatrie, Hôpital A. Chenevier, 40 rue de Mesly, Créteil, F-94010, France.
authors.forename: G
authors.initials: G
authors.lastname: Fond
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.|Department of Public Health, University Hospital, Marseille, France.
authors.forename: P
authors.initials: P
authors.lastname: Auquier
authors.affiliation: Aix-Marseille Univ., EA 3279 Research Unit, 13385 Marseille, France.|Department of Public Health, University Hospital, Marseille, France.
authors.forename: L
authors.initials: L
authors.lastname: Boyer
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005602:France; D006703:Ill-Housed Persons; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy*