title: Defining the primary research question in veterinary clinical studies.
abstract: A thoughtful, clearly defined research question should be the foundation of any clinical trial or research study. The research question helps determine key study methods, and defining a specific research question helps avoid problems with inadequate sample size, inappropriate design, or multiple statistical comparisons. Rationales and strategies for formulating research questions and using them to define study protocols are discussed, with a focus on application in clinical trials.
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Giuffrida
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D012107:Research Design; D014730:Veterinary Medicine