title: The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes.
abstract: OBJECTIVE
  to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels.
  
  
  METHODS
  this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged 60 years old who sought treatment at outpatient clinic of Geriatry and Diabetes Division at Cipto Mangunkusumo Hospital between January and March 2016. Orthostatic hypotension was defined as a decrease in systolic blood pressure 20 mmHg and/or diastolic pressure 10 mmHg within 3 minutes after changing position from lying to standing. HbA1c levels was measured using Nycocard from Axis Shield. Chi square test was used for bivariate analysis and logistic regression was used for multivariate analysis against confounding variables.
  
  
  RESULTS
  the proportion of orthostatic hypotension in elderly subjects with DM was 27.4%. Median of HbA1c levels was higher in subjects with than without orthostatic hypotension (7.6% vs. 7.1%; p<0.05). There was an association between HbA1c levels of 7.35% and the incidence of orthostatic hypotension (OR 1.987, 95% CI 1.2-3.2). The duration of having DM was a confounding variable.
  
  
  CONCLUSIONS
  orthostatic hypotension is more common in elderly subjects with DM. There is an association between the incidence of orthostatic hypotension and increased HbA1c levels in elderly patients with diabetes mellitus.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
authors.forename: Catarina
authors.initials: C
authors.lastname: Budyono
authors.forename: Siti
authors.initials: S
authors.lastname: Setiati
authors.forename: Dyah
authors.initials: D
authors.lastname: Purnamasari
authors.forename: Cleopas M
authors.initials: CM
authors.lastname: Rumende
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000453:epidemiology*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000453:epidemiology*; D015994:Incidence; D007214:Indonesia / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011187:Posture
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human