title: [Treatment of advanced Siewert type Ⅱ esophagogastric junction adenocarcinoma by thoracoabdominal radical gastrectomy and D2 lymphadenectomy].
abstract: OBJECTIVE
  To investigate the advantages of thoracoabdominal radical gastrectomy for advanced Siewert type Ⅱ adenocarcinoma of the esophagogastric junction.
  
  
  METHODS
  Clinical data of 86 patients with Siewert type Ⅱ adennocarcinoma of the esophagogastric junction who received surgical treatment at the Henan Provincial Tumor Hospital from January 2015 to January 2016 were retrospectively analyzed. Among them, 44 patients underwent abdominal operation (abdominal group), and 42 patients underwent thoracoabdominal radical gastrectomy (thoraco-abdominal group). The operation time, lymph node number, distance between the tumor and cutting edge, amount of intraoperational blood loss, postoperative pulmonary complications, and postoperative hospital stay in the two groups were compared.
  
  
  RESULTS
  Comparing the thoracoabdominal group with the abdominal group, the number of removed lymph nodes was 41.57±9.22 vs. 35.09±10.61 (P<0.01), the number of removed mediastinal lymph nodes was 6.38±1.50 vs. 3.52±1.42 (P<0.01), the distance between the tumor and cut edge was (5.62±0.73) cm vs. (3.30±0.85) cm (P<0.01), whereas the operation time, intraoperative blood loss, postoperative pulmonary complications, occurrence of anastomotic leakage and hospital stay were statistically not significantly different (P>0.05 for all).
  
  
  CONCLUSIONS
  For patients with advanced Siewert type Ⅱ adenocarcinoma of the esophagogastric junction, radical gastrectomy through thoracoabdominal approach can resect a longer segment of the esophagus, dissect more mediastinal lymph nodes, and does not increase post-operative complications and extend hospital stay, thus, exhibits obvious advantages in the surgical treatment of Siewert Ⅱ adenocarcinoma of the esophagogastric junction.
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: G S
authors.initials: GS
authors.lastname: Han
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Cao
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: Z C
authors.initials: ZC
authors.lastname: Run
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Zhao
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: Y K
authors.initials: YK
authors.lastname: Ren
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Gu
authors.affiliation: Department of General Surgery, Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University), Zhengzhou 450003, China.
authors.forename: Z M
authors.initials: ZM
authors.lastname: Li
mesh_terms: D000230:Adenocarcinoma; D016063:Blood Loss, Surgical; D004943:Esophagogastric Junction; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D061646:Operative Time; D011183:Postoperative Complications; D012189:Retrospective Studies; D013274:Stomach Neoplasms