title: The Role of the Neurointensive Care Nursery for Neonatal Encephalopathy.
abstract: Neonatal encephalopathy due to intrapartum events is estimated at 1 to 2 per 1000 live births in high-income countries. Outcomes have improved over the past decade due to implementation of therapeutic hypothermia, the only clinically available neuroprotective strategy for hypoxic-ischemic encephalopathy. Neonatal encephalopathy is the most common condition treated within a neonatal neurocritical care unit. Neonates with encephalopathy benefit from a neurocritical care approach due to prevention of secondary brain injury through attention to basic physiology, earlier recognition and treatment of neurologic complications, consistent management using guidelines and protocols, and use of optimized teams at dedicated referral centers.
authors.affiliation: Department of Neurology, Benioff Children's Hospital, University of California San Francisco, 675 Nelson Rising Lane, Room 494, Box 0663, San Francisco, CA 94158, USA; Department of Pediatrics, Benioff Children's Hospital, University of California San Francisco, San Francisco, CA, USA; Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA, USA. Electronic address: Hannah.Glass@ucsf.edu.
authors.forename: Hannah C
authors.initials: HC
authors.lastname: Glass
authors.affiliation: Department of Paediatrics, University of Cambridge, Cambridge, UK; Department of Pediatrics and Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
authors.forename: David H
authors.initials: DH
authors.lastname: Rowitch
mesh_terms: D003299:Cooperative Behavior; D006757:Hospital Units; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000628:therapy*; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D000072156:Neonatologists; D000072141:Neurologists; D009462:Neurology
keywords: Cerebral palsy; Critical care; Hypoxic-ischemic encephalopathy; Infant; Neonatal encephalopathy; Neonatal seizures; Neurocritical care; Therapeutic hypothermia