title: Aldosterone Response in Severe Hypokalemia and Volume Depletion: A Case Report and Review of the Recent Research.
abstract: We report a case of severe hypokalemia and volume depletion complicated by chronic watery diarrhea resulting from chronic alcoholism in a 57-year-old man. Prompt replacement of normal saline with potassium chloride and cessation of alcohol intake resulted in a favorable outcome. We discuss the pathophysiology of the case, emphasizing the response of aldosterone in both hypokalemia and volume depletion, and provide a review of recent research.
authors.affiliation: Division of Nephrology, Kanto Rosai Hospital, Kanagawa 211-8510, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Kai
authors.affiliation: Division of Nephrology, Kanto Rosai Hospital, Kanagawa 211-8510, Japan.
authors.forename: Naoto
authors.identifier: 0000-0002-3699-7418
authors.initials: N
authors.lastname: Tominaga
authors.affiliation: Division of Nephrology, Kanto Rosai Hospital, Kanagawa 211-8510, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Uchida
authors.affiliation: Division of Nephrology, Kanto Rosai Hospital, Kanagawa 211-8510, Japan.
authors.forename: Nanae
authors.initials: N
authors.lastname: Fukai
authors.affiliation: Division of Nephrology, Kanto Rosai Hospital, Kanagawa 211-8510, Japan.
authors.forename: Yumie
authors.identifier: 0000-0003-2542-8305
authors.initials: Y
authors.lastname: Matsuura
authors.affiliation: Division of Nephrology, Kanto Rosai Hospital, Kanagawa 211-8510, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Uda
authors.affiliation: Division of Nephrology, Kanto Rosai Hospital, Kanagawa 211-8510, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Yokochi