title: Evidence of H3 K27M mutations in posterior fossa ependymomas.
authors.affiliation: DGNN Brain Tumor Reference Center, Institute of Neuropathology, University of Bonn Medical Center, 53105, Bonn, Germany.
authors.forename: Marco
authors.initials: M
authors.lastname: Gessi
authors.affiliation: Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, 69120, Heidelberg, Germany.|Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
authors.forename: David
authors.initials: D
authors.lastname: Capper
authors.affiliation: Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, 69120, Heidelberg, Germany.|Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
authors.forename: Felix
authors.initials: F
authors.lastname: Sahm
authors.affiliation: Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, 69120, Heidelberg, Germany.|Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
authors.forename: Kristin
authors.initials: K
authors.lastname: Huang
authors.affiliation: Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, 69120, Heidelberg, Germany.|Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: von Deimling
authors.affiliation: HIT-REZ Study Center, Department of Pediatric Oncology and Hematology, Pediatrics III, University Hospital Essen, 45147, Essen, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Tippelt
authors.affiliation: HIT-REZ Study Center, Department of Pediatric Oncology and Hematology, Pediatrics III, University Hospital Essen, 45147, Essen, Germany.
authors.forename: Gudrun
authors.initials: G
authors.lastname: Fleischhack
authors.affiliation: Department of Pediatric Oncology, University of Ulm, Children's Hospital, 89075, Ulm, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Scherbaum
authors.affiliation: Institute of Pathology Kaufbeuren, 87600, Kaufbeuren, Germany.
authors.forename: Joachim
authors.initials: J
authors.lastname: Alfer
authors.affiliation: HIT-MED Study Center, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
authors.forename: Björn-Ole
authors.initials: BO
authors.lastname: Juhnke
authors.affiliation: HIT-MED Study Center, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
authors.forename: Katja
authors.initials: K
authors.lastname: von Hoff
authors.affiliation: HIT-MED Study Center, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Rutkowski
authors.affiliation: Department of Neuroradiology, German Reference Center for Neuroradiology, University Hospital of Würzburg, 97080, Würzburg, Germany.
authors.forename: Monika
authors.initials: M
authors.lastname: Warmuth-Metz
authors.affiliation: Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
authors.forename: Lukas
authors.initials: L
authors.lastname: Chavez
authors.affiliation: Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.|Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, 69120, Heidelberg, Germany.
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Pfister
authors.affiliation: DGNN Brain Tumor Reference Center, Institute of Neuropathology, University of Bonn Medical Center, 53105, Bonn, Germany.
authors.forename: Torsten
authors.initials: T
authors.lastname: Pietsch
authors.affiliation: Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
authors.forename: David T W
authors.initials: DT
authors.lastname: Jones
authors.affiliation: Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. d.sturm@dkfz.de.|Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, 69120, Heidelberg, Germany. d.sturm@dkfz.de.
authors.forename: Dominik
authors.identifier: 0000-0003-0250-1696
authors.initials: D
authors.lastname: Sturm
mesh_terms: D002648:Child; D004806:Ependymoma / Q000235:genetics*; D005260:Female; D006657:Histones / Q000235:genetics*; D006801:Humans; D007223:Infant; D015192:Infratentorial Neoplasms / Q000235:genetics*; D008239:Lysine / Q000235:genetics; D008715:Methionine / Q000235:genetics*; D009154:Mutation / Q000235:genetics*
chemical_list: C000609950:H3-3A protein, human; D006657:Histones; D008715:Methionine; D008239:Lysine