title: A randomized controlled study comparing the efficacy of nasal saline irrigation devices in children with acute rhinosinusitis.
abstract: OBJECTIVE
  To evaluate the efficacy of positive-pressure nasal irrigation devices in children with acute sinusitis, in addition to bacterial colonization of the irrigation device.
  
  
  METHODS
  We performed a randomized, prospective, controlled study of 80 children with acute sinusitis, aged between 3 and 15 years. Participants were randomly separated into two groups, where one group was treated using a squeezable bottle and the other group treated using a syringe. All patients were instructed to use a 1.25% buffered hypertonic solution for nasal irrigation twice daily for 2 weeks, in addition to amoxicillin-clavulanic acid. During this period, all participants recorded a 5S score, satisfaction score, any side effects and use of antihistamines. Parents were instructed to clean the device with soap after each use. After this period, the nasal irrigation devices were sent to a microbiological laboratory for bacterial identification.
  
  
  RESULTS
  At the 2-week follow-up, improvement in both 5S and satisfaction scores were observed in both groups compared to baseline, which were significantly higher in the group treated with the squeezable bottle compared to the syringe. Few complaints were reported, and side effects were equal in both groups. The overall rate of bacterial contamination for both treatments was approximately 80%, but this did not translate into higher rates of infection amongst patients.
  
  
  CONCLUSIONS
  The use of a squeezable bottle for nasal irrigation in children with acute sinusitis was associated with further improvements in 5S and satisfaction scores compared to syringe use, and there were no significant differences in bacterial contamination between methods.
authors.affiliation: Division of Pulmonology, Department of Pediatrics, Thammasat University, Prathum Thani, Thailand.
authors.forename: Araya
authors.initials: A
authors.lastname: Satdhabudha
authors.affiliation: Oral Biology Research Unit, Faculty of Dentistry, Thammasat University, Prathum Thani, Thailand.
authors.forename: Kusumawadee
authors.initials: K
authors.lastname: Utispan
authors.affiliation: Oral Biology Research Unit, Faculty of Dentistry, Thammasat University, Prathum Thani, Thailand.
authors.forename: Paopaga
authors.initials: P
authors.lastname: Monthanapisut
authors.affiliation: Division of Allergy and Immunology, Department of Pediatrics, Thammasat University, Prathum Thani, Thailand.|Medicinal Herb Research Unit for Asthma, Faculty of Medicine, Thailand.
authors.forename: Orapan
authors.initials: O
authors.lastname: Poachanukoon
mesh_terms: D000208:Acute Disease; D000281:Administration, Intranasal; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D008297:Male; D055556:Nasal Lavage / Q000295:instrumentation*; D017060:Patient Satisfaction; D011446:Prospective Studies; D011788:Quality of Life; D012220:Rhinitis / Q000175:diagnosis / Q000628:therapy*; D000077330:Saline Solution / Q000008:administration & dosage*; D012852:Sinusitis / Q000175:diagnosis / Q000628:therapy*; D007507:Therapeutic Irrigation / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000077330:Saline Solution