title: Current tecniques and new perpectives research of magnetic resonance enterography in pediatric Crohn's disease.
abstract: Crohn's disease affects more than 500000 individuals in the United States, and about 25% of cases are diagnosed during the pediatric period. Imaging of the bowel has undergone dramatic changes in the past two decades. The endoscopy with biopsy is generally considered the diagnostic reference standard, this combination can evaluates only the mucosa, not inflammation or fibrosis in the mucosa. Actually, the only modalities that can visualize submucosal tissues throughout the small bowel are the computed tomography (CT) enterography (CTE) with the magnetic resonance enterography (MRE). CT generally is highly utilized, but there is growing concern over ionizing radiation and cancer risk; it is a very important aspect to keep in consideration in pediatric patients. In contrast to CTE, MRE does not subject patients to ionizing radiation and can be used to detect detailed morphologic information and functional data of bowel disease, to monitor the effects of medical therapy more accurately, to detect residual active disease even in patients showing apparent clinical resolution and to guide treatment more accurately.
authors.affiliation: Gabriele Masselli, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi, Department of Emergency Radiology, First Faculty of Medicine "La Sapienza", University-Hospital Umberto I, 00161 Rome, Italy.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Masselli
authors.affiliation: Gabriele Masselli, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi, Department of Emergency Radiology, First Faculty of Medicine "La Sapienza", University-Hospital Umberto I, 00161 Rome, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Mastroiacovo
authors.affiliation: Gabriele Masselli, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi, Department of Emergency Radiology, First Faculty of Medicine "La Sapienza", University-Hospital Umberto I, 00161 Rome, Italy.
authors.forename: Emidio
authors.initials: E
authors.lastname: De Marco
authors.affiliation: Gabriele Masselli, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi, Department of Emergency Radiology, First Faculty of Medicine "La Sapienza", University-Hospital Umberto I, 00161 Rome, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Francione
authors.affiliation: Gabriele Masselli, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi, Department of Emergency Radiology, First Faculty of Medicine "La Sapienza", University-Hospital Umberto I, 00161 Rome, Italy.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Casciani
authors.affiliation: Gabriele Masselli, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi, Department of Emergency Radiology, First Faculty of Medicine "La Sapienza", University-Hospital Umberto I, 00161 Rome, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Polettini
authors.affiliation: Gabriele Masselli, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi, Department of Emergency Radiology, First Faculty of Medicine "La Sapienza", University-Hospital Umberto I, 00161 Rome, Italy.
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Gualdi
keywords: Crohn’s disease; Enterography; Imaging; Magnetic resonance imaging; Pediatric