title: [Asherman's syndrome I--history, prevalence, histopathology, classification, ethiology, symtomatology and investigations].
abstract: OBJECTIVE
  To describe the current knowledge of Ashermanes syndrome--its history, prevalence, histopathology, classification, ethiology, symtomatology and investigations.
  
  
  METHODS
  Review article.
  
  
  RESULTS
  There is presented the history of definition of Asherman's syndrome. The origin of Asherman's syndrome is in a fibrotisation of endometrium--the ethiologic factors are: an intrauterine trauma in connection with pregnancy, the trauma on nongravid uterus is in minority. There is not certificated that the inflammation without trauma can cause Asherman's syndrome, exception the cases with genital TBC and schistosomiasis. The prevalence of Asherman's syndrome depends on various factors: number of therapeutic and illegal abortions, on incidence of genital inflammation and TBC, on criteria used for diagnosis of IUA and etc. The typical symptomatology of this syndrome consisted of: menstrual abnormalities (hypomenorrhea, amenorrhoea), infertility, repeated pregnancy loss and pregnancy complications. There were described a lot of classifications developed in relation with chosen diagnostic method. The gold standard in diagnosis and therapy is the hysteroscopy, the sonohysterography is very promissing diagnostic method.
  
  
  CONCLUSIONS
  The Asherman's syndrome is very complicated and severe disease that can significantly influence a possibility of woman conceive and give birth to a healthy child.
authors.forename: L
authors.initials: L
authors.lastname: Hrazdirová
authors.forename: D
authors.initials: D
authors.lastname: Kužel
authors.forename: Z
authors.initials: Z
authors.lastname: Žižka
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects; D004717:Endometrium / Q000473:pathology; D005260:Female; D006175:Gynatresia / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D006801:Humans; D015907:Hysteroscopy; D007246:Infertility; D008599:Menstruation Disturbances; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology; D014599:Uterus