title: [Chronic kidney failure and carotid atherosclerosis in diabetic patient].
abstract: BACKGROUND
  Chronic kidney failure is an independent risk factor of cardiovascular disease. Its association with carotid atherosclerosis remains controversial. The purpose of our study was to assess the factors associated with carotid atherosclerosis specially the components of chronic kidney disease.
  
  
  METHODS
  In a cross-sectional study, we enrolled type 1 or type 2 diabetic patients from the endocrinology an diabetology department of the military hospital of Rabat assigned in two groups according to the presence or absence of carotid atherosclerosis. Kidney function was assessed based on albuminuria and the estimated glomerular filtration rate calculated using the "modification of diet in renal disease" equation. A multiple logistic regression analysis was performed to identify independent factors associated with carotid atherosclerosis.
  
  
  RESULTS
  One hundred and six diabetic patients were enrolled including 96 type 2 diabetic patients. Age (P<0.001), diabetes duration (P=0.04), hypertension (P=0.002), peripheral arterial disease (P<0.001) and chronic kidney failure (P=0.001) were significantly associated with carotid atherosclerosis. After adjusting for age, hypertension, diabetes duration and peripheral arterial disease, chronic kidney failure was an independent factor associated with carotid atherosclerosis (OR: 5.46; 95%IC: 1.29-23.01; P=0.021).
  
  
  CONCLUSIONS
  Our data suggest that chronic kidney failure is associated with carotid atherosclerosis in diabetic patients independently of the common cardiovascular risk factors.
authors.affiliation: Université Mohammed V, faculté de médecine et de pharmacie, hôpital militaire d'instruction Mohammed V, service d'endocrinologie et de diabétologie, avenue des FAR-Hay-Riad, 10100 Rabat, Maroc. Electronic address: moumen2105@gmail.com.
authors.forename: Amal
authors.initials: A
authors.lastname: Moumen
authors.affiliation: Université Mohammed V, faculté de médecine et de pharmacie, faculté de médecine dentaire de Rabat, laboratoire de biostatistique, de recherche clinique et d'épidémiologie, département de parodontologie, Rabat, Maroc.
authors.forename: Amal
authors.initials: A
authors.lastname: Bouziane
authors.affiliation: Université Mohammed V, faculté de médecine et de pharmacie, hôpital militaire d'instruction Mohammed V, service d'endocrinologie et de diabétologie, avenue des FAR-Hay-Riad, 10100 Rabat, Maroc.
authors.forename: Azzelarab
authors.initials: A
authors.lastname: Meftah
authors.affiliation: Université Mohammed V, faculté de médecine et de pharmacie, hôpital militaire d'instruction Mohammed V, service d'endocrinologie et de diabétologie, avenue des FAR-Hay-Riad, 10100 Rabat, Maroc.
authors.forename: Yassine
authors.initials: Y
authors.lastname: Errahali
authors.affiliation: Université Mohammed V, faculté de médecine et de pharmacie, hôpital militaire d'instruction Mohammed V, service d'endocrinologie et de diabétologie, avenue des FAR-Hay-Riad, 10100 Rabat, Maroc.
authors.forename: Hamza
authors.initials: H
authors.lastname: Eljadi
authors.affiliation: Université Mohammed V, faculté de médecine et de pharmacie, hôpital militaire d'instruction Mohammed V, service d'endocrinologie et de diabétologie, avenue des FAR-Hay-Riad, 10100 Rabat, Maroc.
authors.forename: Souad
authors.initials: S
authors.lastname: Elmoussaoui
authors.affiliation: Université Mohammed V, faculté de médecine et de pharmacie, hôpital militaire d'instruction Mohammed V, service d'endocrinologie et de diabétologie, avenue des FAR-Hay-Riad, 10100 Rabat, Maroc.
authors.forename: Ghizlaine
authors.initials: G
authors.lastname: Belmejdoub
mesh_terms: D002340:Carotid Artery Diseases / Q000150:complications*; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003925:Diabetic Angiopathies / Q000150:complications*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors