title: Intravitreal Bevacizumab for Choroidal Neovascular Membrane at the Edge of a Healed Choroidal Tuberculoma.
abstract: The authors present a 36-year-old female with pulmonary tuberculosis who developed a choroidal tuberculoma in the left eye. The choroidal tuberculoma successfully resolved with visual gain following oral anti-tubercular and oral steroid therapy leaving behind a chorioretinal scar. One year after the completion of anti-tubercular treatment, she developed visual loss due to the development of a secondary choroidal neovascular membrane at the fovea. This was treated successfully with one intravitreal injection of bevacizumab in the left eye. The fovea remained free of fluid until the last follow-up 10 months after the intravitreal injection. Intravitreal bevacizumab may be an effective modality for treating secondary choroidal neovascular membranes that may form at the edge of a healed choroidal tuberculoma.
authors.affiliation: a Department of Ophthalmology , Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences , New Delhi , India.
authors.forename: Koushik
authors.identifier: http://orcid.org/0000-0002-9756-128X
authors.initials: K
authors.lastname: Tripathy
authors.affiliation: a Department of Ophthalmology , Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences , New Delhi , India.
authors.forename: Rohan
authors.initials: R
authors.lastname: Chawla
authors.affiliation: a Department of Ophthalmology , Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences , New Delhi , India.
authors.forename: Yog Raj
authors.initials: YR
authors.lastname: Sharma
mesh_terms: D000328:Adult; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000068258:Bevacizumab / Q000627:therapeutic use*; D020256:Choroidal Neovascularization / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D058449:Intravitreal Injections; D058471:Subretinal Fluid; D041623:Tomography, Optical Coherence; D014375:Tuberculoma / Q000150:complications* / Q000000981:diagnostic imaging; D014392:Tuberculosis, Ocular / Q000150:complications* / Q000000981:diagnostic imaging; D014397:Tuberculosis, Pulmonary / Q000150:complications; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors; D014792:Visual Acuity / Q000502:physiology
chemical_list: D020533:Angiogenesis Inhibitors; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D000068258:Bevacizumab
keywords: Anti-vascular endothelial growth factor agents; choroidal tubercle; ocular tuberculosis; subretinal fluid; subretinal tubercular abscess