title: Native bivalvular endocarditis by Gemella haemolysans requiring venovenous extracorporeal membrane oxygenation.
abstract: A 24-year-old otherwise healthy man presented with a 3-week history of malaise, headache, fever and rigors after he was treated with oral clindamycin for left parotitis and Gemella haemolysans bacteraemia. He developed G. haemolysans infective endocarditis, septic emboli and heart failure due to progressive bivalvular disease. He underwent urgent mechanical aortic valve replacement and mitral valve repair, which required venovenous extracorporeal membrane oxygenation, to support severe respiratory failure. This is the first documented case of G. haemolysans infective endocarditis affecting native aortic and mitral valves in a healthy adult.
authors.affiliation: Department of Internal Medicine, University of Hawaii System, Honolulu, Hawaii, USA.
authors.forename: Akika
authors.initials: A
authors.lastname: Ando
authors.affiliation: Department of Internal Medicine, University of Hawaii System, Honolulu, Hawaii, USA.
authors.forename: Jaclyn
authors.initials: J
authors.lastname: Kagihara
authors.affiliation: Department of Internal Medicine, University of Hawaii System, Honolulu, Hawaii, USA.
authors.forename: Heath
authors.initials: H
authors.lastname: Chung
authors.affiliation: Department of Internal Medicine, University of Hawaii System, Honolulu, Hawaii, USA Queen's Hospitalist Program, Queen's Medical Center, Honolulu, Hawaii, USA.
authors.forename: Dennis Thomas
authors.initials: DT
authors.lastname: Bolger
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001021:Aortic Valve / Q000382:microbiology* / Q000601:surgery; D016470:Bacteremia / Q000188:drug therapy; D002981:Clindamycin / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery*; D015199:Extracorporeal Membrane Oxygenation; D058834:Gemella; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology* / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000382:microbiology* / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin