title: Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea.
abstract: The aim of the present study was to determine the antibiotic resistance patterns and distribution of heavy-metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea; and to determine the relationship, if any, between antibiotic and heavy-metal resistance in these strains. Among the 15 strains isolated, two strains, SY1 and SY2, showed heavy-metal resistance in addition to high resistance to seven antibiotics: cephalothin, gentamicin, erythromycin, vancomycin, ampicillin, rifampicin, and streptomycin. We conclude that heavy-metal contamination imposes long-term, widespread, and recalcitrant selection pressure, which potentially contributes to the maintenance and spread of antibiotic resistance factors in bacteria. Moreover, this fact holds both environmental and clinical importance.
authors.affiliation: Department of Biological Engineering, Inha University, Republic of Korea.
authors.forename: Chang-Ho
authors.initials: CH
authors.lastname: Kang
authors.affiliation: Department of Biological Engineering, Inha University, Republic of Korea. Electronic address: sjaeseon@inha.ac.kr.
authors.forename: Jae-Seong
authors.initials: JS
authors.lastname: So
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000302:isolation & purification; D004352:Drug Resistance, Microbial / Q000235:genetics*; D004784:Environmental Monitoring; D004917:Erythromycin; D019216:Metals, Heavy; D008826:Microbial Sensitivity Tests; D056910:Republic of Korea; D012758:Shellfish / Q000382:microbiology*; D020614:Shewanella putrefaciens / Q000502:physiology*; D014873:Water Pollutants
chemical_list: D000900:Anti-Bacterial Agents; D019216:Metals, Heavy; D014873:Water Pollutants; D004917:Erythromycin
keywords: Antibiotic; Heavy metal; Interaction; Resistance; Shewanella putrefaciens