title: Effect of Brace to Osteoporotic Vertebral Fracture: a Meta-Analysis.
abstract: Brace is one of the most commonly used interventions to manage osteoporotic vertebral fracture. However, its authentic effectiveness remains unclear. The aim of this study was to investigate the efficacy of brace in patients with osteoporotic vertebral fractures. We conducted a literature review and meta-analysis following the guideline and handbook of the Cochrane collaboration. Ten published articles were included in this study and data from 4 randomized controlled trials were analyzed. Low quality evidence proved using Spinomed brace could bring large and significant beneficial effect to patients with sub-acute osteoporotic vertebral fractures. Very low quality evidence proved no significant difference between Spinomed orthosis, rigid brace and soft brace when they were used in patients with acute fractures. Therefore, it might be applicable to recommend middle term use of Spinomed orthosis to patients with subacute fracture. In addition, this study emphasized the need for high quality randomized controlled trials.
authors.affiliation: Department of Orthopedic Surgery, College of Medicine, Seoul National University, Seoul, Korea.
authors.forename: Yuan Zhe
authors.identifier: http://orcid.org/0000-0001-9068-2778
authors.initials: YZ
authors.lastname: Jin
authors.affiliation: Department of Orthopedic Surgery, College of Medicine, Seoul National University, Seoul, Korea.|Department of Orthopedic Surgery, SMG-SNU Boramae Medical Center, Seoul, Korea. spinelee@snu.ac.kr.
authors.forename: Jae Hyup
authors.identifier: http://orcid.org/0000-0002-2141-0266
authors.initials: JH
authors.lastname: Lee
mesh_terms: D001915:Braces; D002986:Clinical Trials as Topic; D016208:Databases, Factual; D006801:Humans; D010024:Osteoporosis / Q000150:complications; D058866:Osteoporotic Fractures / Q000209:etiology / Q000628:therapy*; D012306:Risk
keywords: Brace; Fracture; Meta-Analysis; Osteoporosis; Spine