title: [Epidemiologic features of myeloma in Szabolcs-Szatmár-Bereg county, Hungary. Analysis of data of a 33-year period].
abstract: BACKGROUND
  In their previous work, the authors reported findings from 30 years on the incidence of hematological malignancies in Szabolcs-Szatmár-Bereg county, Hungary. Until now there are no other studies on this topic available in Hungary.
  
  
  OBJECTIVE
  Detailed analysis of epidemiologic features of patients with myeloma.
  
  
  METHODS
  During a 33-year period (between January 1, 1983 and December 31, 2015) 4521 adult patients with hematologic malignancies were recorded in the leukaemia/lymphoma registry of Szabolcs-Szatmár-Bereg county. Among them 440 patients with myeloma (9.73%) were registered (397 multiple myeloma, 38 solitary, bone/soft tissue plasmocytoma, 5 primary plasma cell leukaemia).
  
  
  RESULTS
  The incidence of myeloma in Szabolcs-Szatmár-Bereg county showed an increasing tendency, with an overall incidence rate of 2.33/100 000 inhabitants/year. The male:female ratio was 45.9%:54.1%, the average age of patients was 65.1 (28-90) years, and 59.4% of the patients with multiple myeloma had IgG-type monoclonal immunoglobulin. There was no town or village in this county where the occurrence of patients with myeloma in one thousand inhabitants was significantly higher, than the average (0.78).
  
  
  CONCLUSIONS
  The epidemiologic features of myeloma in Szabolcs-Szatmár-Bereg county - except a moderate female dominance - is essentially similar to data published in the literature. Orv. Hetil., 2016, 157(34), 1357-1360.
authors.affiliation: Hematológiai Osztály, Szabolcs-Szatmár-Bereg Megyei Jósa András Oktatókórház Nyíregyháza.
authors.forename: János
authors.initials: J
authors.lastname: Jakó
authors.affiliation: Hematológiai Osztály, Szabolcs-Szatmár-Bereg Megyei Jósa András Oktatókórház Nyíregyháza.
authors.forename: László
authors.initials: L
authors.lastname: Szerafin
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D015994:Incidence; D008223:Lymphoma / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000453:epidemiology*; D054219:Neoplasms, Plasma Cell / Q000453:epidemiology*; D010954:Plasmacytoma / Q000453:epidemiology*; D011634:Public Health / Q000639:trends; D012042:Registries; D017678:Sex Distribution
keywords: Szabolcs-Szatmár-Bereg county; Szabolcs-Szatmár-Bereg megye; familiar occurrence; familiaritás; geographic distribution of patients; hematological malignancies; incidence rate; incidencia; malignus hematológiai kórképek; myeloma; myeloma and carcinoma; myeloma és carcinoma társulása; sex and age distribution; területi eloszlás; életkor és nemek szerinti megoszlás