title: [Serious delayed intracranial complications after mild traumatic brain injury in oral anticoagulant use].
abstract: Patients with mild traumatic brain injury (TBI) who use anticoagulants prior to injury have an increased risk of intracranial complications. Sometimes these complications are delayed, even if the initial CT scan of the head is normal.
  
  
  
  An 84-year-old woman who was using acenocoumarol presented elsewhere with mild TBI. She had no focal neurological deficit. The initial CT scan revealed no abnormalities and the patient was discharged home. That evening she had diffuse headache. The next day she was found with a reduced level of consciousness and was brought to our hospital. Her INR was 9.0 and a new CT scan showed an acute, left-sided subdural haematoma with a large mass effect.
  
  
  
  Serious delayed intracranial complications in patients with mild TBI who use anticoagulants are rare. In these patients INR measurement and a CT scan of the head are always indicated. Admission for observation may be considered. On discharge it is necessary to give clear instructions about warning symptoms.
authors.affiliation: Erasmus MC, Rotterdam.
authors.forename: K A
authors.initials: KA
authors.lastname: Foks
authors.forename: V
authors.initials: V
authors.lastname: Volovici
authors.forename: L E
authors.initials: LE
authors.lastname: Kwee
authors.forename: I K
authors.initials: IK
authors.lastname: Haitsma
authors.forename: D W J
authors.initials: DW
authors.lastname: Dippel
mesh_terms: D000074:Acenocoumarol / Q000009:adverse effects*; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects*; D000070642:Brain Injuries, Traumatic / Q000150:complications*; D005260:Female; D020199:Hematoma, Subdural, Acute / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D019934:International Normalized Ratio; D013997:Time Factors
chemical_list: D000925:Anticoagulants; D000074:Acenocoumarol