title: Prevalence of High Non-high-density Lipoprotein Cholesterol and Associated Risk Factors in Patients with Diabetes Mellitus in Jilin Province, China: A Cross-sectional Study.
abstract: Dyslipidemia is a risk factor for cardiovascular diseases (CVDs) in patients with diabetes, and non-high-density lipoprotein cholesterol (non-HDL-C) is a better predictor of CVDs than low-density lipoprotein cholesterol (LDL-C) in patients with diabetes. Therefore, we aimed to investigate the distribution of non-HDL-C and the prevalence of high non-HDL-C level in Chinese patients with diabetes mellitus and identify the associated risk factors. Non-HDL-C concentration positively correlated with total cholesterol, triglycerides, and LDL-C concentrations. Although both non-HDL-C and LDL-C concentration both related positively with TC concentration, the magnitude of correlation was relatively higher for non-HDL-C. The prevalence of high non-HDL-C (⋝4.14 mmol/L) was higher in two age groups (55-64 years: 46.7%; 65-79 years: 47.3%) than other age groups (18-24 years: 4.2%; 25-34 years: 43.6%; 35-44 years: 38.1%; 45-54 years: 41.0%). It was also higher among overweight (45.1%), generally obese (50.9%), or abdominally obese (47.3%) subjects, compared with normal weight subjects (34.5%). The risk of high non-HDL-C increased with advancing age. Both general obesity [odds ratio (OR)=1.488, 95% confidence interval (CI): 1.003-2.209] and abdominal obesity (OR=1.561, 95% CI: 1.101-2.214) were significantly associated with high non-HDL-C levels.
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Huan
authors.initials: H
authors.lastname: He
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhen
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Chang Gui
authors.initials: CG
authors.lastname: Kou
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Yu Chun
authors.initials: YC
authors.lastname: Tao
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Chang
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Joseph Sam
authors.initials: JS
authors.lastname: Kanu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Yu Ping
authors.initials: YP
authors.lastname: Lu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Ming Xi
authors.initials: MX
authors.lastname: Yu
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, VA Medical Center, West Haven, CT 06516, USA .
authors.forename: Hui Ping
authors.initials: HP
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Ya Qin
authors.initials: YQ
authors.lastname: Yu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, Jinlin, China.
authors.forename: Ya Wen
authors.initials: YW
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D055815:Young Adult