title: Fe-Catalyzed Aerobic Oxidative C-CN Bond Cleavage of Arylacetonitriles Leading to Various Esters.
abstract: Fe-catalyzed aerobic oxidative esterifications of arylacetonitriles with alcohols, tri alkoxsilanes, silicate esters, or borate esters have been developed. The acyl groups which were in situ generated via chemoselective C(CO)-CN bond cleavage were directly used as electrophiles, leading to corresponding aryl esters in good to excellent yields under molecular oxygen when attacked by alcohols or alcohol surrogates. Dioxygen serves as both oxidant and reactant in this protocol. The reaction has a very broad substrate scope. Cheap starting materials as well as environmentally benign and inexpensive iron catalyst and ideal oxidant O2 feature this transformation and make it a practical and sustainable protocol to afford esters.
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering, College of Materials Science & Engineering, Huaqiao University , 668 Jimei Blvd, Xiamen, Fujian 361021, P. R. China.
authors.forename: Weiguang
authors.initials: W
authors.lastname: Kong
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering, College of Materials Science & Engineering, Huaqiao University , 668 Jimei Blvd, Xiamen, Fujian 361021, P. R. China.
authors.forename: Bingnan
authors.initials: B
authors.lastname: Li
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering, College of Materials Science & Engineering, Huaqiao University , 668 Jimei Blvd, Xiamen, Fujian 361021, P. R. China.
authors.forename: Xuezhao
authors.initials: X
authors.lastname: Xu
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering, College of Materials Science & Engineering, Huaqiao University , 668 Jimei Blvd, Xiamen, Fujian 361021, P. R. China.|Beijing National Laboratory for Molecular Sciences , Beijing, 100190, China.
authors.forename: Qiuling
authors.initials: Q
authors.lastname: Song