title: [Case-control study on individual osteotomy instrument and conventional total knee arthroplasty for the treatment of knee osteoarthritis].
abstract: OBJECTIVE
  To compare clinical efficacy of individual osteotomy instrument and total knee arthrolplasty (TKA) in treating patients with knee osteoarthritis.
  
  
  METHODS
  From June 2014 to December 2014, 40 patients with unilateral knee osteoarthritis were randomly divided into two groups and 20 cases were in each group. One group (individual group) were treated with TKA with individual osteotomy instrument,including 5 males and 15 females with an average age of (67.3 ± 6.5) years old; 8 cases on the left side and 12 cases on the right side. Another group (conventional group) were treated with conventional TKA , including 6 males and 14 females with an average age of (66.8 ± 7.3) years old; 9 cases on the left side and 11 cases on the right side. Operative time, blood loss, postoperative HSS score at 6 months, and changes of mechanical alignment before and after operation were analyzed.
  
  
  RESULTS
  Operative time in individual group was (79.3 ± 4.7) min, and (83.5 ± 3.2) min in conventional group; blood loss in individual group was (287.1 ± 24.9) ml and (363.4 ± 47.2) ml in conventional group, there were statistical differences between two groups in these two items. There was no significant difference in postoperative HSS score at 6 months between individual group (84.8 ± 3.2) and conventional group (84.2 ± 2.5). Postoperative limb alignment in individual group was (2.8 ± 0.6)°, and (2.8 ± 0.6)° in conventional group, with no significant difference between two groups.
  
  
  CONCLUSIONS
  TKA with individual osteotomy instrument could reduce operative time and blood loss, but there was no differences in knee function, changes of mechanical alignment compared with TKA.
authors.forename: Hua-chen
authors.initials: HC
authors.lastname: Yu
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Paul
authors.initials: P
authors.lastname: Wong
mesh_terms: D000328:Adult; D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000379:methods; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D008297:Male; D061646:Operative Time; D020370:Osteoarthritis, Knee / Q000601:surgery*; D010027:Osteotomy / Q000295:instrumentation* / Q000379:methods; D016896:Treatment Outcome