title: Oligometastatic prostate cancer: Metastases-directed therapy?
abstract: Since the introduction of anatomical and functional imaging with multiparametric magnetic resonance imaging and choline or prostate-specific membrane antigen positron emission tomography-computed tomography, we are able to diagnose a previously unknown disease, the oligometastatic prostate cancer after local therapy. Reports on surgical and radiation treatment for low-volume metastatic recurrence have shown promising results, with definitive cure in few but a relevant delay of androgen-deprivation therapy with both treatment methods. Obviously, these results need to be validated with prospective randomised data.
authors.affiliation: Department of Urology and Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Hein
authors.initials: H
authors.lastname: Van Poppel
authors.affiliation: Department of Urology and Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Gert
authors.initials: G
authors.lastname: De Meerleer
authors.affiliation: Department of Urology and Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Steven
authors.initials: S
authors.lastname: Joniau
keywords: (SB)RT, (stereotactic body) radiotherapy; ADT, androgen-deprivation therapy; BRFS, biochemical recurrence-free survival; CPFS, clinical progression-free survival; CSS, cancer-specific survival; LND, lymph node dissection; Lymph node dissection; Oligometastatic prostate cancer; PET, positron emission tomography; Stereotactic body radiotherapy