title: IgE-Mediated Reaction to Metamizole: Evaluation of a Patient with Severe Anaphylaxis.
abstract: Metamizole, a non-steroidal anti-inflammatory drug with weak anti-inflammatory and spasmolytic effects, is used as an analgesic and antipyretic agent. Many adverse reactions to metamizole, such as early or late-onset systemic reactions and bone marrow suppression, have been identified. In this report, we present a case of systemic reaction after the application of parenteral metamizole (Novalgin(®) ampoule; Sanofi Aventis, İstanbul, Turkey) and discuss the mechanism underlying the reaction.
authors.affiliation: Division of Immunology and Allergic Disease, Necmettin Erbakan University School of Medicine, Konya, Turkey.
authors.forename: Sevket
authors.initials: S
authors.lastname: Arslan
authors.affiliation: Division of Immunology and Allergic Disease, Necmettin Erbakan University School of Medicine, Konya, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Ucar
authors.affiliation: Division of Immunology and Allergic Disease, Necmettin Erbakan University School of Medicine, Konya, Turkey.
authors.forename: Ahmet Zafer
authors.initials: AZ
authors.lastname: Caliskaner
keywords: Abdominal pain; metamizole; systemic reactions