title: Identification of a gammaherpesvirus belonging to the malignant catarrhal fever group of viruses in Pyrenean chamois (Rupicapra p. pyrenaica).
abstract: High prevalence (46 %) of a gammaherpesvirus was confirmed by molecular detection in the lungs of hunted Pyrenean chamois. The partial glycoprotein B sequence up to the DNA polymerase gene showed 96.6 % nucleotide sequence identity to the Rupicapra rupicapra gammaherpesvirus 1 and 81.5 % to ovine herpesvirus 2. This novel sequence clusters within sequences derived from the malignant catarrhal fever group of viruses, and the corresponding virus is tentatively named Rupicapra pyrenaica gammaherpesvirus 1 (RpHV-1). No specific histological lesions were associated with RpHV-1, nor were any detrimental effects on host health. The epidemiological, phylogenetic and histopathological results suggest that Pyrenean chamois is the natural host of RpHV-1.
authors.affiliation: Servei d'Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. xfdezaguilar@gmail.com.|IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. xfdezaguilar@gmail.com.
authors.forename: Xavier
authors.identifier: http://orcid.org/0000-0002-4939-6048
authors.initials: X
authors.lastname: Fernández-Aguilar
authors.affiliation: Centro de Investigación en Sanidad Animal (INIA-CISA), Carretera Algete a El Casar s/n, 28140, Valdeolmos, Madrid, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Esperón
authors.affiliation: Servei d'Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.|IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Oscar
authors.initials: O
authors.lastname: Cabezón
authors.affiliation: Servei d'Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Roser
authors.initials: R
authors.lastname: Velarde
authors.affiliation: Servei d'Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Gregorio
authors.initials: G
authors.lastname: Mentaberre
authors.affiliation: Centro de Investigación en Sanidad Animal (INIA-CISA), Carretera Algete a El Casar s/n, 28140, Valdeolmos, Madrid, Spain.
authors.forename: Verónica
authors.initials: V
authors.lastname: Delicado
authors.affiliation: Centro de Investigación en Sanidad Animal (INIA-CISA), Carretera Algete a El Casar s/n, 28140, Valdeolmos, Madrid, Spain.
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Muñoz
authors.affiliation: Servei d'Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.|CESAM, Departamento de Biologia Universidade de Aveiro, Aveiro, Portugal.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Serrano
authors.affiliation: Servei d'Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Santiago
authors.initials: S
authors.lastname: Lavín
authors.affiliation: Servei d'Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Jorge Ramón
authors.initials: JR
authors.lastname: López-Olvera
mesh_terms: D000818:Animals; D058345:Asymptomatic Infections; D016000:Cluster Analysis; D018142:Gammaherpesvirinae / Q000145:classification* / Q000302:isolation & purification*; D006023:Glycoproteins / Q000235:genetics; D006566:Herpesviridae Infections / Q000662:veterinary* / Q000821:virology; D008168:Lung / Q000821:virology; D010802:Phylogeny; D048608:Rupicapra / Q000821:virology*; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D015678:Viral Structural Proteins / Q000235:genetics
chemical_list: D006023:Glycoproteins; D015678:Viral Structural Proteins
keywords: Bronchopneumonia; Chamois; Gammaherpesvirus; Macavirus; Malignant catarrhal fever; Wildlife