title: Ins and Outs of Multipartite Positive-Strand RNA Plant Viruses: Packaging versus Systemic Spread.
abstract: Viruses possessing a non-segmented genome require a specific recognition of their nucleic acid to ensure its protection in a capsid. A similar feature exists for viruses having a segmented genome, usually consisting of viral genomic segments joined together into one viral entity. While this appears as a rule for animal viruses, the majority of segmented plant viruses package their genomic segments individually. To ensure a productive infection, all viral particles and thereby all segments have to be present in the same cell. Progression of the virus within the plant requires as well a concerted genome preservation to avoid loss of function. In this review, we will discuss the "life aspects" of chosen phytoviruses and argue for the existence of RNA-RNA interactions that drive the preservation of viral genome integrity while the virus progresses in the plant.
authors.affiliation: Institut de Biologie Moléculaire des Plantes, Integrative Virology, CNRS UPR2367, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France. mattia.dallara5@unibo.it.|Dipartimento di Scienze Agrarie, Area Patologia Vegetale, Università di Bologna, Viale Fanin 40, 40127 Bologna, Italy. mattia.dallara5@unibo.it.
authors.forename: Mattia
authors.initials: M
authors.lastname: Dall'Ara
authors.affiliation: Dipartimento di Scienze Agrarie, Area Patologia Vegetale, Università di Bologna, Viale Fanin 40, 40127 Bologna, Italy. claudio.ratti@unibo.it.
authors.forename: Claudio
authors.initials: C
authors.lastname: Ratti
authors.affiliation: Institut de Biologie Moléculaire des Plantes, Integrative Virology, CNRS UPR2367, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France. salah.bouzoubaa@ibmp-cnrs.unistra.fr.
authors.forename: Salah E
authors.initials: SE
authors.lastname: Bouzoubaa
authors.affiliation: Institut de Biologie Moléculaire des Plantes, Integrative Virology, CNRS UPR2367, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France. gilmer@unistra.fr.
authors.forename: David
authors.initials: D
authors.lastname: Gilmer
mesh_terms: D010942:Plant Viruses / Q000502:physiology*; D010944:Plants / Q000821:virology*; D012328:RNA Viruses / Q000502:physiology*; D019065:Virus Assembly
keywords: RNA-RNA interaction; genome integrity; phytovirus; segmented genome; systemic movement