title: Primary intraosseous meningioma: an osteosclerotic bone tumour mimicking malignancy.
abstract: BACKGROUND
  Sclerotic tumours of the calvarial bones are rare and may be due to primary and secondary bone tumours as well as extradural tumours of meningeal origin.
  
  
  METHODS
  We report a case of primary intraosseous meningioma (PIM) which arose in the frontal bone of a 63 year old woman who complained of progressive pain and thickening of the right skull. Radiology showed a large osteosclerotic lesion in the right frontal bone. Histology showed an intraosseous lesion containing dense fibrous tissue in which there were scattered cells that expressed epithelial membrane antigen and progesterone receptor. The tumour was partially resected and 3 years after operation has not recurred.
  
  
  CONCLUSIONS
  PIM is a rare tumour which needs to be distinguished from primary/secondary osteosclerotic calvarial bone tumours.
authors.affiliation: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre Windmill Road, Oxford, OX3 7HE UK.
authors.forename: M
authors.initials: M
authors.lastname: Vlychou
authors.affiliation: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre Windmill Road, Oxford, OX3 7HE UK.
authors.forename: Y
authors.initials: Y
authors.lastname: Inagaki
authors.affiliation: Department of Neurosurgery, John Radcliffe Hospital, Oxford University Hospitals, Headley Way, Oxford, OX3 9DU UK.
authors.forename: R
authors.initials: R
authors.lastname: Stacey
authors.affiliation: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre Windmill Road, Oxford, OX3 7HE UK.
authors.forename: N A
authors.initials: NA
authors.lastname: Athanasou
keywords: Calvarium; Intraosseous; Meningioma; Skull