title: [Treatment of constipation in palliative care patients is a challenge].
abstract: The evidence for treatment of constipation in palliative care patients is poor. The condition of these patients is often complex, and results from studies performed in other patient groups cannot be extrapolated unconditionally. However, macrogol (polyethylene glycol), lactulose and sodium picosulphate seem to be well tolerated, and methylnaltrexone could be used in opioid-induced constipation, if the patients are not at risk from gastrointestinal perforation. The patients should be offered quiet and private surroundings, and attention should be payed to securing an optimal body position for defecation.
authors.affiliation: ljarlbaek@sdu.dk.
authors.forename: Lene
authors.initials: L
authors.lastname: Jarlbæk
authors.forename: Berit
authors.initials: B
authors.lastname: Johnsen
authors.forename: Ole Bo
authors.initials: OB
authors.lastname: Hansen
authors.forename: Birte
authors.initials: B
authors.lastname: Hedal
mesh_terms: D000701:Analgesics, Opioid / Q000627:therapeutic use; D003248:Constipation / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy; D003672:Defecation / Q000502:physiology; D019317:Evidence-Based Medicine; D006801:Humans; D054368:Laxatives / Q000627:therapeutic use; D010166:Palliative Care; D011187:Posture / Q000502:physiology
chemical_list: D000701:Analgesics, Opioid; D054368:Laxatives