title: Drug-Induced Tendon Disorders.
abstract: Drug-induced tendon disorders are an often underestimated risk factor. The range from detrimental effects on the tendon include tendinopathy as well as potentially tendon rupture. As for today, four main drug classes have been reported to be associated with potentially deteriorated tendon properties: 1. Corticosteroids, 2. Chinolon antibiotics, 3. Aromatase inhbitors, 4. Statins as HMG-CoA-reductase inhibitors. Most often, the Achilles tendon is affected in terms of tendinopathy and/or subsequent tendon rupture. However, nearly every tendon of the entire body might be affected in a detrimental way by one or a combination of the aformentioned agents.
authors.affiliation: SportPraxis Prof. Knobloch, Heiligerstr. 3, Hannover, 30159, Germany. professor.knobloch@sportpraxis-knobloch.de.
authors.forename: Karsten
authors.initials: K
authors.lastname: Knobloch
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D047072:Aromatase Inhibitors / Q000009:adverse effects*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D052256:Tendinopathy / Q000139:chemically induced* / Q000473:pathology; D013710:Tendons / Q000187:drug effects* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D047072:Aromatase Inhibitors; D005938:Glucocorticoids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors
keywords: Adverse effect; Aromatase inhibitor; Chinolon; Corticosteroid; Statin; Tendon; Tendon rupture; Treatment