title: Very Long-Term Follow-Up After Coronary Rotational Atherectomy: A Single-Center Experience.
abstract: We assessed the very long-term follow-up of a large cohort of unselected patients treated with coronary rotational atherectomy (RA). All 143 patients who underwent RA at our institution from 2000 to 2013 and with complete baseline and follow-up information were analyzed in a retrospective manner. Major adverse cardiac events (MACE) were defined as the composite of target vessel revascularization (TVR), acute myocardial infarction, and all-cause mortality. The mean follow-up was 8.2 years. The 10-year cumulative incidence of MACE for all patients was 57.9% (standard error [SE]: 5.0%). When comparing patients who received a drug-eluting stent (DES; n = 68) versus patients who did not (balloon only, bare-metal stent, or none of the aforementioned; n = 75), the RA + DES demonstrated very long-term MACE of 49.2% (SE: 7.5%) versus 62.7% (SE: 6.1%), P = .160 with TVR as the most discriminating factor, 10.7% (SE: 4.0%) versus 29.2% (SE: 6.0%), P = .016. Our results point to RA having reasonable long-term clinical results, especially in combined treatment with DES. To date, our study has the longest follow-up after RA.
authors.affiliation: 1 Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.|2 Department of Cardiology, Assiut University Hospital, Assiut, Egypt.
authors.forename: Aly
authors.initials: A
authors.lastname: Tohamy
authors.affiliation: 1 Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Margo
authors.initials: M
authors.lastname: Klomp
authors.affiliation: 3 Department of Medical Statistics, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Hein
authors.initials: H
authors.lastname: Putter
authors.affiliation: 2 Department of Cardiology, Assiut University Hospital, Assiut, Egypt.
authors.forename: Amr
authors.initials: A
authors.lastname: Youssef
authors.affiliation: 2 Department of Cardiology, Assiut University Hospital, Assiut, Egypt.
authors.forename: Hamdy
authors.initials: H
authors.lastname: Shams-Eddin
authors.affiliation: 2 Department of Cardiology, Assiut University Hospital, Assiut, Egypt.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Abdelsabour
authors.affiliation: 1 Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: M J
authors.initials: MJ
authors.lastname: Schalij
authors.affiliation: 1 Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: J Wouter
authors.initials: JW
authors.lastname: Jukema
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017225:Atherectomy, Coronary / Q000379:methods*; D003131:Combined Modality Therapy; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: coronary intervention; long-term follow-up; rotational atherectomy; stent