title: Chinese herbal medicine for atopic eczema: an overview of clinical evidence.
abstract: Atopic eczema (AE), or atopic dermatitis, is a common inflammatory skin disease. As conventional medicines for moderate and severe AE patients have been reported to be associated with unwanted side effects, many patients with AE have sought other therapies. Chinese herbal medicine (CHM) is one of the most commonly used complementary therapies with a long history of being applied for the treatment of AE. Clinical evidence for CHM for AE in systematic reviews and randomised controlled trials (RCTs) published from 2013 to 2016 was reviewed. Findings from the Cochrane systematic review suggested that oral use of a CHM formulation may improve health-related quality of life (HRQoL) of children with moderate or severe AE. The benefit on improvement of AE requires further high-quality clinical studies.
authors.affiliation: a China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences , RMIT University , Bundoora Campus , Melbourne , Australia.
authors.forename: Sherman X
authors.initials: SX
authors.lastname: Gu
authors.affiliation: a China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences , RMIT University , Bundoora Campus , Melbourne , Australia.
authors.forename: Anthony L
authors.initials: AL
authors.lastname: Zhang
authors.affiliation: a China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences , RMIT University , Bundoora Campus , Melbourne , Australia.
authors.forename: Meaghan E
authors.initials: ME
authors.lastname: Coyle
authors.affiliation: b Guangdong Provincial Hospital of Chinese Medicine and Guangdong Provincial Academy of Chinese Medical Sciences , Guangzhou , China.
authors.forename: Dacan
authors.initials: D
authors.lastname: Chen
authors.affiliation: a China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences , RMIT University , Bundoora Campus , Melbourne , Australia.|b Guangdong Provincial Hospital of Chinese Medicine and Guangdong Provincial Academy of Chinese Medical Sciences , Guangzhou , China.
authors.forename: Charlie C
authors.initials: CC
authors.lastname: Xue
mesh_terms: D002648:Child; D002986:Clinical Trials as Topic; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000473:pathology; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D011788:Quality of Life; D012720:Severity of Illness Index; D013154:Spleen / Q000378:metabolism / Q000473:pathology
chemical_list: D004365:Drugs, Chinese Herbal
keywords: Atopic eczema; Chinese herbal medicine; atopic dermatitis; randomised controlled trials; systematic review