title: Simultaneous Use of Intravenous Lipid Emulsion and Plasma Exchange Therapies in Multiple Drug Toxicity.
abstract: OBJECTIVE
  The aim of this study was to highlight the use of combined intravenous lipid emulsion (ILE) and plasma exchange (PE) therapies in multidrug toxicity.
  
  
  METHODS
  A 45-year-old woman who attempted suicide by ingesting large quantities of amisulpride (28 g), diazepam (250 mg), valsartan (2,240 mg), aripiprazole (45 mg) and paliperidone (21 mg) was taken to the hospital of Adnan Menderes University School of Medicine. Upon arrival, she exhibited signs of cardiotoxicity and severe depression of the central nervous and respiratory systems. She was treated successfully with ILE for 4 h and PE therapy for 36 h, consecutively. She was discharged on the fourth day of hospitalization having fully recovered.
  
  
  CONCLUSIONS
  The patient was successfully treated with the combination of ILE and PE.
authors.affiliation: Department of Emergency Medicine, Adnan Menderes University Hospital, Aydın, Turkey.
authors.forename: Mucahit
authors.initials: M
authors.lastname: Avcil
authors.forename: Mucahit
authors.initials: M
authors.lastname: Kapçı
authors.forename: Irfan
authors.initials: I
authors.lastname: Yavaşoğlu
authors.forename: Burçak
authors.initials: B
authors.lastname: Kantekin
authors.forename: Mahmut
authors.initials: M
authors.lastname: Akpek
mesh_terms: D000077582:Amisulpride; D000959:Antihypertensive Agents / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D000068180:Aripiprazole / Q000009:adverse effects; D003975:Diazepam / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions / Q000628:therapy*; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects; D007022:Hypotension / Q000628:therapy; D008875:Middle Aged; D000068882:Paliperidone Palmitate / Q000009:adverse effects; D010951:Plasma Exchange; D013406:Suicide, Attempted; D013469:Sulpiride / Q000009:adverse effects / Q000031:analogs & derivatives; D016896:Treatment Outcome; D014421:Turkey; D000068756:Valsartan / Q000009:adverse effects
chemical_list: D000959:Antihypertensive Agents; D014150:Antipsychotic Agents; D005217:Fat Emulsions, Intravenous; D006993:Hypnotics and Sedatives; D013469:Sulpiride; D000068756:Valsartan; D000077582:Amisulpride; D000068180:Aripiprazole; D003975:Diazepam; D000068882:Paliperidone Palmitate