title: Renewing caregiver health and wellbeing through exercise (RECHARGE): A randomized controlled trial.
abstract: Family caregivers (FCs) to cancer patients are at increased risk for physical and emotional health problems as a result of being in the caregiver role. Current research on interventions for FCs has focused on psychological support or educational interventions, with very little investigation of exercise in maintaining or improving health. Based on our preliminary survey, participation in regular exercise to improve health was noted as a priority for FCs. The purpose of the study described in this protocol is to examine the impact of a 12-week structured exercise program on physical functioning (primary outcome), physical activity levels and psychological well-being (secondary outcomes), in FCs caring for adult cancer patients. In addition, the trial described here will examine the outcomes from a 12-week maintenance program, immediately following the initial program.
  
  
  
  A mixed methods design using a randomized control trial (RCT) with a 50/50 allocation ratio for the quantitative portion, followed by face to face interviews and qualitative data analysis. Approximately 86 participants will be enrolled over a 10 month period. The intervention will consist of a structured exercise program of aerobic and resistance training. An intention to treat principle using mixed effects modeling will guide data analysis.
  
  
  
  FCs will continue to play a pivotal role in the care of cancer patients as the incidence and chronicity of cancer increases. The research described in this protocol will provide information about the impact of an exercise program in supporting FC health.
  
  
  
  ClinicalTrials.gov Identifier: NCT02580461.
authors.affiliation: Faculty of Nursing, University of Calgary, 2800 University Way N.W., University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; Alberta Health Services, Cancer Care, Tom Baker Cancer Center, 1331 - 29th Street N.W., Calgary, AB T2N 4N2, Canada. Electronic address: cacuthbe@ucalgary.ca.
authors.forename: Colleen A
authors.initials: CA
authors.lastname: Cuthbert
authors.affiliation: Faculty of Nursing, University of Calgary, 2800 University Way N.W., University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada; Cumming School of Medicine, Department of Community Health Sciences, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada. Electronic address: kingk@ucalgary.ca.
authors.forename: Kathryn
authors.initials: K
authors.lastname: King-Shier
authors.affiliation: Faculty of Nursing, University of Calgary, 2800 University Way N.W., University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada. Electronic address: dtapp@ucalgary.ca.
authors.forename: Dianne M
authors.initials: DM
authors.lastname: Tapp
authors.affiliation: Alberta Health Services, Cancer Care, Tom Baker Cancer Center, 1331 - 29th Street N.W., Calgary, AB T2N 4N2, Canada; Cumming School of Medicine, Division of Medical Oncology, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada. Electronic address: dean.ruether@albertahealthservices.ca.
authors.forename: Dean
authors.initials: D
authors.lastname: Ruether
authors.affiliation: Cumming School of Medicine, University of Calgary, 3330 Hospital Drive NW,Calgary, Alberta T2N 4N1. Electronic address: cljackso@ucalgary.ca.
authors.forename: Colleen
authors.initials: C
authors.lastname: Jackson
authors.affiliation: Faculty of Kinesiology, University of Calgary, KNB 2229, 2500 University Drive N.W., Calgary, AB T2N 1N4, Canada; Cumming School of Medicine, Division of Medical Oncology, Department of Psychosocial Oncology, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada. Electronic address: nculosre@ucalgary.ca.
authors.forename: S Nicole
authors.initials: SN
authors.lastname: Culos-Reed
mesh_terms: D017028:Caregivers / Q000523:psychology*; D005081:Exercise Therapy / Q000379:methods* / Q000523:psychology*; D006801:Humans; D008603:Mental Health; D010349:Patient Compliance; D010809:Physical Fitness; D011788:Quality of Life; D012107:Research Design; D012890:Sleep; D012959:Socioeconomic Factors; D013997:Time Factors
keywords: Cancer; Exercise; Family caregivers; Quality of life; Randomized controlled trial