title: Effects of pre- and postnatal exposure to 1880-1900MHz DECT base radiation on development in the rat.
abstract: In the present study, to evaluate the effects of wireless 1880-1900MHz Digital Enhanced Communication Telephony (DECT) base radiation on fetal and postnatal development, Wistar rats were exposed at an average electric field intensity of 3.7V/m, 12h/day, during pregnancy. After parturition, a group of dams and offspring were similarly exposed for another 22days. Controls were sham-exposed. The data showed that DECT base radiation exposure caused heart rate increase in the embryos on the 17th day of pregnancy. Moreover, significant changes on the newborns' somatometric characteristics were noticed. Pyramidal cell loss and glia fibrilliary acidic protein (GFAP) over-expression were detected in the CA4 region of the hippocampus of the 22-day old pups that were irradiated either during prenatal life or both pre- and postnatally. Changes in the integrity of the brain in the 22-day old pups could potentially be related to developmental behavioral changes during the fetal period.
authors.affiliation: Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis 15784, Zografou, Athens, Greece; Laboratory Animal Facilities, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Stasinopoulou
authors.affiliation: Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis 15784, Zografou, Athens, Greece. Electronic address: adamantia.fragkopoulou@ki.se.
authors.forename: A F
authors.initials: AF
authors.lastname: Fragopoulou
authors.affiliation: Biology - Biochemistry Laboratory, Faculty of Nursing, School of Health Sciences, 11527 Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Stamatakis
authors.affiliation: Laboratory Animal Facilities, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece; Veterinary Department, Medical Directorate of Hellenic Airforce General Staff, Athens, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Mantziaras
authors.affiliation: Department of Energy Technology Engineering, Technological Educational Institute of Athens, 12210 Athens, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Skouroliakou
authors.affiliation: Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis 15784, Zografou, Athens, Greece.
authors.forename: I S
authors.initials: IS
authors.lastname: Papassideri
authors.affiliation: Biology - Biochemistry Laboratory, Faculty of Nursing, School of Health Sciences, 11527 Athens, Greece.
authors.forename: F
authors.initials: F
authors.lastname: Stylianopoulou
authors.affiliation: Department of Bioengineering, University of Washington, Box 355061, Seattle, WA 98195-5061, USA.
authors.forename: H
authors.initials: H
authors.lastname: Lai
authors.affiliation: Laboratory Animal Facilities, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Kostomitsopoulos
authors.affiliation: Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis 15784, Zografou, Athens, Greece.
authors.forename: L H
authors.initials: LH
authors.lastname: Margaritis
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism / Q000473:pathology; D004574:Electromagnetic Fields; D047108:Embryonic Development; D005260:Female; D005298:Fertility; D047109:Fetal Development; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006339:Heart Rate; D008098:Litter Size; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D017208:Rats, Wistar; D013689:Telephone
chemical_list: C000614142:Gfap protein, rat; D005904:Glial Fibrillary Acidic Protein
keywords: Cordless phones; Embryos; Fertility; GFAP; Gestation period; Hippocampus; Offspring; Ultrasound