title: Platelet-rich fibrin combined with synthetic nanocrystalline hydroxy apatite granules in the management of radicular cyst.
abstract: Radicular cysts are inflammatory jaw cysts confined to the apices of teeth with infected and necrotic pulp. They arise from the epithelial residues in the periodontal ligament as a result of inflammation, following the death of pulp. The treatment of such lesions vary with regard to their sizes; the small cystic lesions heal after an endodontic therapy, but larger lesions, may require additional treatment. Apical surgery for radicular cysts generally involves apical root resection and sealing with endodontic material. This case report, describes the treatment of a cyst related to the maxillary central and lateral incisors using platelet rich fibrin along with synthetic nanocrystalline hydroxyapatite granules for the regeneration of lost tissues. A follow-up evaluation at 6 months and 1-year revealed a significant radiographic bone fill with satisfactory healing at the surgical site.
authors.affiliation: Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Karnataka, India.
authors.forename: K
authors.initials: K
authors.lastname: Pradeep
authors.affiliation: Department of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal, Karnataka, India.
authors.forename: Adarsh
authors.initials: A
authors.lastname: Kudva
authors.affiliation: Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Karnataka, India.
authors.forename: Vidya
authors.initials: V
authors.lastname: Narayanamoorthy
authors.affiliation: Department of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal, Karnataka, India.
authors.forename: K M
authors.initials: KM
authors.lastname: Cariappa
authors.affiliation: Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Karnataka, India.
authors.forename: M Vidya
authors.initials: MV
authors.lastname: Saraswathi
mesh_terms: D000328:Adult; D001047:Apicoectomy; D005260:Female; D006801:Humans; D006882:Hydroxyapatites / Q000627:therapeutic use*; D007180:Incisor; D008437:Maxilla; D053758:Nanoparticles; D000073183:Platelet-Rich Fibrin; D011842:Radicular Cyst / Q000601:surgery / Q000628:therapy*; D012390:Root Canal Therapy; D014945:Wound Healing
chemical_list: D006882:Hydroxyapatites