title: Colonic transendoscopic enteral tubing: A novel way of transplanting fecal microbiota.
abstract: OBJECTIVE
  Placement of a tube through the anus into the cecum has not yet been established as a method of administering whole-colonic treatment. The aim of this study was to evaluate the safety, feasibility, and value of transendoscopic enteral tubing (TET) for fecal microbiota transplantation (FMT) through the colon.
  
  
  METHODS
  A prospective observational study was performed of FMT using a new colonic TET technique. Under endoscopic guidance, a TET tube was affixed to the cecum with clips. The safety, value, and satisfaction with the FMT by TET were evaluated.
  
  
  RESULTS
  A total of 54 patients underwent TET. The success rate of the TET procedure was 100 % (54/54). Duration of the TET procedures was 14.8 ± 5.8 min. During the TET tube retention period, 98.1 % (53/54) of patients were satisfied with TET. The retention time for whole-colon delivery of the fecal microbiota suspension was 12.4 ± 2.3 days. In 88.4 % (49/54) of cases, no discomfort was reported during injection through the TET tube of the microbiota suspension. No adverse events were see in patients who required tube extubation after FMT.
  
  
  CONCLUSIONS
  Colonic TET is a novel, safe, convenient, and reliable procedure for FMT that results in a high degree of patient satisfaction.
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Zhaoyuan
authors.initials: Z
authors.lastname: Peng
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xiang
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: He
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Lijuan
authors.initials: L
authors.lastname: Xu
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Bota
authors.initials: B
authors.lastname: Cui
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Pan
authors.initials: P
authors.lastname: Li
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Guangming
authors.initials: G
authors.lastname: Huang
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Guozhong
authors.initials: G
authors.lastname: Ji
authors.affiliation: State Key Laboratory of Cancer Biology & Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Yongzhan
authors.initials: Y
authors.lastname: Nie
authors.affiliation: State Key Laboratory of Cancer Biology & Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Kaichun
authors.initials: K
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Cancer Biology & Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Daiming
authors.initials: D
authors.lastname: Fan
authors.affiliation: Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.
authors.forename: Faming
authors.initials: F
authors.lastname: Zhang