title: Efficacy of Phacotrabeculectomy Alone versus Phacotrabeculectomy Augmented with Autologous Anterior Capsule Implantation Beneath the Sclera Flap.
abstract: OBJECTIVE
  To evaluate the efficacy of autologous anterior lens capsule (ALC) in phacotrabeculectomy.
  
  
  METHODS
  In this prospective, randomized case control study, after obtaining institutional ethical clearance and informed consent, 88 eyes posted for phacotrabeculectomy were divided into ALC and non-ALC groups. Combined phacoemulsification, with posterior chamber intraocular lens implantation and trabeculectomy, was performed in both groups. Anterior lens capsule transplantation was done in the first group beneath the sclera flap. Follow-up of three months was carried out and the morphology of bleb, intraocular pressure (IOP), requirement for additional medications, and complications were compared between the two groups.
  
  
  RESULTS
  Statistical difference favoring the ALC group was seen in IOP reduction (p < 0.05) at each follow-up, qualified success rate and failure rate at the three-month follow-up (p = 0.006), but no difference in bleb morphology was seen.
  
  
  CONCLUSIONS
  ALC implantation is beneficial in maintaining filtration in a combined surgery with minimal complications.
authors.affiliation: a University College of Medical Sciences and GTB Hospital, Delhi University , Delhi , India.
authors.forename: Gopal K
authors.initials: GK
authors.lastname: Das
authors.affiliation: a University College of Medical Sciences and GTB Hospital, Delhi University , Delhi , India.
authors.forename: P K
authors.initials: PK
authors.lastname: Sahu
authors.affiliation: a University College of Medical Sciences and GTB Hospital, Delhi University , Delhi , India.
authors.forename: Sabitabh
authors.initials: S
authors.lastname: Kumar
authors.affiliation: a University College of Medical Sciences and GTB Hospital, Delhi University , Delhi , India.
authors.forename: Laura V L
authors.initials: LVL
authors.lastname: Biakthangi
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002386:Cataract / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007903:Lens Capsule, Crystalline / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011446:Prospective Studies; D012590:Sclera / Q000601:surgery*; D013524:Surgical Flaps; D014130:Trabeculectomy / Q000379:methods*; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014792:Visual Acuity
keywords: Bleb morphology; combined surgery; glaucoma; intraocular pressure; lens capsule