title: Asymmetric additions of thioglycolates and N-Boc aldimines catalyzed by a bifunctional tertiary-amine squaramide.
abstract: A highly enantioselective asymmetric addition reaction of thioglycolates and N-Boc aldimines was promoted by a bifunctional tertiary-amine squaramide catalyst. As a result, a number of chiral N,S-acetal derivatives were efficiently synthesized with good enantioselectivities.
authors.affiliation: State Key Laboratory of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Department of Chemistry, Nankai University, Tianjin 300071, P. R. China.
authors.forename: Bo-Xu
authors.initials: BX
authors.lastname: Feng
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Xin
authors.initials: X
authors.lastname: Li
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D007097:Imines / Q000737:chemistry*; D011803:Quinine / Q000031:analogs & derivatives* / Q000737:chemistry; D013237:Stereoisomerism; D013864:Thioglycolates / Q000737:chemistry*
chemical_list: D000588:Amines; D007097:Imines; D013864:Thioglycolates; C000609819:squaramide; D011803:Quinine