title: Hydrolytic Metallo-Nanozymes: From Micelles and Vesicles to Gold Nanoparticles.
abstract: Although the term nanozymes was coined by us in 2004 to highlight the enzyme-like properties of gold nanoparticles passivated with a monolayer of Zn(II)-complexes in the cleavage of phosphate diesters, systems resembling those metallo-nanoparticles, like micelles and vesicles, have been the subject of investigation since the mid-eighties of the last century. This paper reviews what has been done in the field and compares the different nanosystems highlighting the source of catalysis and frequent misconceptions found in the literature.
authors.affiliation: Department of Chemical Sciences, University of Padova, via Marzolo, 1, Padova 35131, Italy. fabrizio.mancin@unipd.it.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Mancin
authors.affiliation: Department of Chemical Sciences, University of Padova, via Marzolo, 1, Padova 35131, Italy. leonard.prins@unipd.it.
authors.forename: Leonard J
authors.initials: LJ
authors.lastname: Prins
authors.affiliation: Department of Chemical and Pharmaceutical Sciences, University of Trieste, via Giorgieri, 1, Trieste 34127, Italy. ppengo@units.it.
authors.forename: Paolo
authors.initials: P
authors.lastname: Pengo
authors.affiliation: Department of Chemical and Pharmaceutical Sciences, University of Trieste, via Giorgieri, 1, Trieste 34127, Italy. lpasquato@units.it.
authors.forename: Lucia
authors.initials: L
authors.lastname: Pasquato
authors.affiliation: Department of Chemical and Pharmaceutical Sciences, University of Trieste, via Giorgieri, 1, Trieste 34127, Italy. ptecilla@units.it.
authors.forename: Paolo
authors.initials: P
authors.lastname: Tecilla
authors.affiliation: Department of Chemical Sciences, University of Padova, via Marzolo, 1, Padova 35131, Italy. paolo.scrimin@unipd.it.
authors.forename: Paolo
authors.initials: P
authors.lastname: Scrimin
mesh_terms: D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D053768:Metal Nanoparticles / Q000737:chemistry*; D008823:Micelles; D015394:Molecular Structure; D017967:Zinc Compounds / Q000737:chemistry*
chemical_list: D005290:Ferric Compounds; D008823:Micelles; D017967:Zinc Compounds; D006046:Gold
keywords: Cu(II); Zn(II); aggregation colloids; carboxylate cleavage; gold nanoparticles; hydrolysis; micelles; phosphate cleavage; vesicles