title: 68Ga-PSMA PET/CT False-Positive Tracer Uptake in Paget Disease.
abstract: 65-year-old man with left-sided pelvic pain on evaluation was found to have features suggestive of either Paget disease or prostatic bone metastasis of the left hemipelvis based on Tc-MDP bone scan and MRI. Ga-PSMA PET/CT to assess the possibility of primary prostate cancer and if present to stage it helped to rule out prostate cancer because of absence of focal abnormal increased tracer uptake in the prostate gland. However, false-positive tracer uptake was noted in the left hemipelvis, which was subject to biopsy and histopathologically proven to be Paget disease involvement.
authors.affiliation: From the KIMS-DDNMRC, KIMS Hospital, Thiruvananthapuram, Kerala, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Sasikumar
authors.forename: Ajith
authors.initials: A
authors.lastname: Joy
authors.forename: Raviteja
authors.initials: R
authors.lastname: Nanabala
authors.forename: M R A
authors.initials: MR
authors.lastname: Pillai
authors.forename: Hari
authors.initials: H
authors.lastname: T A
mesh_terms: D000368:Aged; D000954:Antigens, Surface / Q000737:chemistry* / Q000378:metabolism*; D001692:Biological Transport; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D043425:Glutamate Carboxypeptidase II / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008297:Male; D010001:Osteitis Deformans / Q000000981:diagnostic imaging* / Q000378:metabolism*; D000072078:Positron Emission Tomography Computed Tomography; D011471:Prostatic Neoplasms / Q000473:pathology
chemical_list: D000954:Antigens, Surface; C473848:FOLH1 protein, human; D043425:Glutamate Carboxypeptidase II