title: Supra-Tenon Capsule Implantation of the Ahmed Glaucoma Valve in Refractory Pediatric Glaucoma.
abstract: To evaluate the efficacy of supra-Tenon capsule implantation of an Ahmed glaucoma valve (AGV) as a measure to decrease the fibrotic potential of the Tenon capsule on bleb formation and its subsequent effect on intraocular pressure (IOP) control in children with refractory glaucoma.
  
  
  
  Mansoura Ophthalmic Centre, Faculty of Medicine, Mansoura University, Egypt.
  
  
  
  A prospective interventional study.
  
  
  
  Twenty-two eyes of 12 children with refractory glaucoma underwent supra-Tenon capsule implantation of AGV. Ophthalmic examinations under general anesthesia including measurement of the corneal diameter and the IOP with Perkin's tonometer were performed preoperatively, on the first postoperative day, the first postoperative week, weekly for the first month, 2-weekly for the following 3 months, and monthly for at least 18 months. Postoperative complications and the number of glaucoma medications used preoperatively and postoperatively were recorded. The paired Student t test was used to compare preoperative and postoperative data.
  
  
  
  There were 12 eyes (54.6%) with refractory congenital glaucoma, 7 eyes (31.8%) with refractory pseudophakic glaucoma, and 3 eyes (13.6%) with refractory aphakic glaucoma. Patients included 10 male (83.3%) and 2 female (16.7%) children with a mean age of 16.3±9.7 months. The mean follow-up duration was 24.1±4.3 months. There was a statistically significant difference between the mean preoperative IOP (30.7±2.88 mm Hg) and the mean postoperative IOP (16.1±3.60 mm Hg) (t=16.22 and P=0.000, with a mean decrease in the IOP by 47.6%). The difference between the mean number of antiglaucoma medications before surgery (1.86±0.4) and after surgery (1.0±0.9) was also statistically significant (t=4.31 and P=0.000). Total success was achieved in 18 eyes (81.9%). Postoperative complications included tube exposure and slippage (10%), hypotony (10%), and hyphema (5%).
  
  
  
  Supra-Tenon capsule implantation of the AGV was successful in controlling the IOP with few postoperative complications in the management of children with refractory glaucoma.
authors.affiliation: Faculty of Medicine, Mansoura University, Mansoura, Egypt.
authors.forename: Eman M
authors.initials: EM
authors.lastname: Elhefney
authors.forename: Hossam T
authors.initials: HT
authors.lastname: Al-Sharkawy
authors.forename: Hanem M
authors.initials: HM
authors.lastname: Kishk
mesh_terms: D000293:Adolescent; D000959:Antihypertensive Agents / Q000008:administration & dosage; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D020327:Glaucoma Drainage Implants; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D006871:Hydrophthalmos / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D007429:Intraocular Pressure / Q000187:drug effects / Q000502:physiology; D008297:Male; D011183:Postoperative Complications; D011446:Prospective Studies; D019919:Prosthesis Implantation; D058475:Tenon Capsule / Q000601:surgery*; D014065:Tonometry, Ocular; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents