title: BRAF Mutations Open Doors for N-Ethyl-N-Nitrosourea-Induced Gliomagenesis.
abstract: This commentary highlights the article by Wang et al that describes a preclinical model for targeting BRAF-mutant gliomas.
authors.affiliation: Pathobiology and Translational Science Graduate Program, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
authors.forename: Robert S
authors.initials: RS
authors.lastname: McNeill
authors.affiliation: Curriculum in Genetics and Molecular Biology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
authors.forename: David M
authors.initials: DM
authors.lastname: Irvin
authors.affiliation: Pathobiology and Translational Science Graduate Program, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Curriculum in Genetics and Molecular Biology, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Department of Neurology and Neurosciences Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina. Electronic address: rmiller@med.unc.edu.
authors.forename: C Ryan
authors.initials: CR
authors.lastname: Miller
mesh_terms: D005038:Ethylnitrosourea; D005910:Glioma / Q000235:genetics*; D006319:Hearing Loss, Sensorineural; D006801:Humans; D009154:Mutation / Q000187:drug effects
chemical_list: D005038:Ethylnitrosourea