title: Energy parasites trigger oncogene mutation.
abstract: Cancer initialization can be explained as a result of parasitic virus energy consumption leading to randomized genome chemical bonding.
  
  
  
  Analysis of experimental data on cell-mediated immunity (CMI) containing about 12,000 cases of healthy humans, cancer patients and patients with precancerous cervical lesions disclosed that the specific cancer and the non-specific lactate dehydrogenase-elevating (LDH) virus antigen elicit similar responses. The specific antigen is effective only in cancer type of its origin but the non-specific antigen in all examined cancers. CMI results of CIN patients display both healthy and cancer state. The ribonucleic acid (RNA) of the LDH virus parasitizing on energy reduces the ratio of coherent/random oscillations. Decreased effect of coherent cellular electromagnetic field on bonding electrons in biological macromolecules leads to elevating probability of random genome reactions.
  
  
  
  Overlapping of wave functions in biological macromolecules depends on energy of the cellular electromagnetic field which supplies energy to bonding electrons for selective chemical bonds. CMI responses of cancer and LDH virus antigens in all examined healthy, precancerous and cancer cases point to energy mechanism in cancer initiation.
  
  
  
  Dependence of the rate of biochemical reactions on biological electromagnetic field explains yet unknown mechanism of genome mutation.
authors.affiliation: a Institute of Physics, Czech Academy of Sciences , Prague , Czech Republic ;
authors.forename: Jiří
authors.initials: J
authors.lastname: Pokorný
authors.affiliation: a Institute of Physics, Czech Academy of Sciences , Prague , Czech Republic ;
authors.forename: Jan
authors.initials: J
authors.lastname: Pokorný
authors.affiliation: b Institute of Photonics and Electronics, Czech Academy of Sciences , Prague , Czech Republic ;
authors.forename: Anna
authors.initials: A
authors.lastname: Jandová
authors.affiliation: c 1st Faculty of Medicine, Department of Obstetrics and Gynaecology , Charles University , Prague , Czech Republic ;
authors.forename: Jitka
authors.initials: J
authors.lastname: Kobilková
authors.affiliation: d Faculty of Electrical Engineering , Czech Technical University in Prague , Prague , Czech Republic ;
authors.forename: Jan
authors.initials: J
authors.lastname: Vrba
authors.affiliation: e Faculty of Biomedical Engineering , Czech Technical University in Kladno , Kladno , Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Vrba
mesh_terms: D003198:Computer Simulation; D004574:Electromagnetic Fields; D006801:Humans; D007772:Lactate dehydrogenase-elevating virus / Q000502:physiology; D008956:Models, Chemical; D008957:Models, Genetic; D018448:Models, Immunological; D009154:Mutation / Q000235:genetics* / Q000528:radiation effects; D009369:Neoplasms / Q000235:genetics* / Q000276:immunology* / Q000821:virology; D009857:Oncogenes / Q000235:genetics* / Q000276:immunology* / Q000528:radiation effects; D013601:T-Lymphocytes / Q000276:immunology / Q000528:radiation effects / Q000821:virology
keywords: Cancer initiation; LDH virus; cell-mediated immunity; coherent electromagnetic states; genome somatic mutation; parasitic energy consumption