title: Vitamin D Toxicity; Stored and Released from Adipose Tissue?
abstract: Vitamin D is a pro-hormone that plays an important role in body calcium regulation. Vitamin D toxicity occurs rarely due to its wide therapeutic index. A 38-year-old Iranian man was admitted to our hospital with a diagnosis of vitamin D toxicity. Laboratory test revealed hypercalcemia and elevated 25-hydroxyvitamin D (25(OH)D) level. Despite the cessation of vitamin D intake and diuretic treatment, he presented four months later with high 25(OH)D level and similar clinical features. Due to the potential release of vitamin D from adipose tissue, serial monitoring of 25(OH)D level is recommended.
authors.affiliation: Nephrology Research Center, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Ziaie
authors.affiliation: Neuroscience Department, Carleton University, Ottawa, Canada.
authors.forename: Sara
authors.initials: S
authors.lastname: Razmjou
authors.affiliation: Nephrology Research Center, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Rohollah
authors.initials: R
authors.lastname: Jomhouri
authors.affiliation: Assistant Professor of Nephrology. Nephrology Research Center, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Arya
authors.initials: A
authors.lastname: Jenabi
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry*; D000328:Adult; D002118:Calcium / Q000097:blood*; D004562:Electrocardiography; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis*; D007492:Iran; D008297:Male; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood / Q000633:toxicity*
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D; D002118:Calcium