title: [Iron-based Phosphate Binders for ESRD Patients].
abstract: Several factors influence the choice of phosphate binder for patients, including older age, male gender, post-menopause, diabetes, low bone turnover, vascular/valvular calcification and inflammation. Unlike calcium-based phosphate binders, non-calcium-based phosphate binders, such as sevelamer and lanthanum carbonate, have been able to reduce the progression of bone disease to adynamic bone among patients with CKD. New iron-based phosphate binders are now available. With multiple options available for the reduction of phosphate, the focus has been on agents that do not contain calcium. This is because it is thought that calcium itself functions as a substrate for calcification.
authors.forename: Mario
authors.initials: M
authors.lastname: Cozzolino
authors.forename: Michela
authors.initials: M
authors.lastname: Mangano
authors.forename: Lorenza
authors.initials: L
authors.lastname: Magagnoli
authors.forename: Luca
authors.initials: L
authors.lastname: Di Lullo
authors.forename: Andrea
authors.initials: A
authors.lastname: Galassi
authors.forename: Diego
authors.initials: D
authors.lastname: Brancaccio
authors.forename: Antonio
authors.initials: A
authors.lastname: Bellasi
mesh_terms: D002254:Carbonates / Q000627:therapeutic use*; D002614:Chelating Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D005290:Ferric Compounds / Q000627:therapeutic use*; D006801:Humans; D054559:Hyperphosphatemia / Q000188:drug therapy* / Q000209:etiology*; D007501:Iron / Q000627:therapeutic use*; D007676:Kidney Failure, Chronic / Q000150:complications*; D008274:Magnesium / Q000627:therapeutic use*; D010710:Phosphates / Q000378:metabolism*; D013395:Sucrose / Q000627:therapeutic use*
chemical_list: D002254:Carbonates; D002614:Chelating Agents; D004338:Drug Combinations; D005290:Ferric Compounds; D010710:Phosphates; C000599459:sucroferric oxyhydroxide; D013395:Sucrose; C025314:ferric citrate; D007501:Iron; D008274:Magnesium; C541219:iron-magnesium hydroxycarbonate