title: Isomeric differentiation of chloroanilines by gas chromatography-mass spectrometry in combination with tosylation.
abstract: p-Chloroaniline is one of the banned aromatic amines in azo dyes, but it is very difficult to distinguish it from its isomers due to their identical retention time in chromatography and similar mass spectra. In this work, derivatization of the isomeric chloroanilines was carried out to yield the corresponding N-tosyl chloroanilines, which were completely separated by gas chromatography and also possessed clearly different electron ionization mass spectra. Thus, the three isomers could be differentiated and determined at the same time. Density functional theory calculation results indicated that the effect of the substituent pattern in electron ionization mass spectrometry is mainly due to the difference in the stability of the product ion (P2) at m/z 126, originating from the loss of tosyl radical from the precursor ion.
authors.affiliation: Key Laboratory of Organosilicon Chemistry and Material Technology, Hangzhou Normal University, Hangzhou, 311121, China.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Wang
authors.affiliation: Zhejiang Province Environmental Monitoring Center, Hangzhou, 310015, China.
authors.forename: Guohua
authors.initials: G
authors.lastname: Zhu
authors.affiliation: Key Laboratory of Organosilicon Chemistry and Material Technology, Hangzhou Normal University, Hangzhou, 311121, China.
authors.forename: Mengmeng
authors.initials: M
authors.lastname: Chen
authors.affiliation: Zhejiang Province Environmental Monitoring Center, Hangzhou, 310015, China.
authors.forename: Jinsong
authors.initials: J
authors.lastname: Liu
authors.affiliation: Key Laboratory of Organosilicon Chemistry and Material Technology, Hangzhou Normal University, Hangzhou, 311121, China. jiangkezhi@hznu.edu.cn.
authors.forename: Kezhi
authors.initials: K
authors.lastname: Jiang