title: Long-term risks for patency loss in patients with hemodialysis after bare self-expandable nitinol stent implantation to femoropopliteal artery occlusive lesions.
abstract: BACKGROUND
  Although patients receiving hemodialysis (HD+) have significantly different backgrounds, including a history of progressive atherosclerotic disease, compared with those not receiving hemodialysis (HD-), there are no studies evaluating the risks for loss of primary patency (PP) and need for target lesion revascularization (TLR) in HD+ patients following bare self-expandable nitinol stent (BSNS) implantation to femoropopliteal (FP) artery occlusive lesions, after adjusting for differences using propensity score (PS) analysis in observed characteristics between groups.
  
  
  METHODS
  We studied 531 limbs of 432 Japanese patients (HD+, n=107; HD-, n=325) who received BSNS implantation to FP lesions between 2004 and 2014. Patients were followed-up for an average of 44.3±33.6months. We compared the long-term results between HD+ and HD- patients using the Cox-proportional hazard model with adjustment for inverse probability treatment weight (IPTW) of PS, which was calculated for covariates with HD as a dependent variable.
  
  
  RESULTS
  PP rate in HD+ vs. HD- patients at 9years after the procedure was 19.1% vs. 47.9%, with a freedom from TLR rate of 47.6% vs. 62.9%, respectively. Adjusted HRs in HD+ patients with 95% confidence intervals (CIs) were as follows: loss of PP: HR 1.64, 95% CI 1.052-2.557, P=0.03; TLR: HR 1.862, 95% CI 1.104-3.139, P=0.02.
  
  
  CONCLUSIONS
  The present study suggests that HD+ patients have an increased risk for loss of PP and need for TLR after BSNS implantation to FP lesions.
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: mjunya2318@gmail.com.
authors.forename: Junya
authors.initials: J
authors.lastname: Matsumi
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: takada0924takuma@icloud.com.
authors.forename: Takuma
authors.initials: T
authors.lastname: Takada
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: e2718nm@gmail.com.
authors.forename: Noriaki
authors.initials: N
authors.lastname: Moriyama
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: qqzd72y9k@ever.ocn.ne.jp.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Ochiai
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: memento_mori_foram@yahoo.co.jp.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Tobita
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: koki10192002@yahoo.co.jp.
authors.forename: Koki
authors.initials: K
authors.lastname: Shishido
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: sugitatsu0706@yahoo.co.jp.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Sugitatsu
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: radialist-children@song.ocn.ne.jp.
authors.forename: Shingo
authors.initials: S
authors.lastname: Mizuno
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: futoshi-yamanaka@nifty.com.
authors.forename: Futoshi
authors.initials: F
authors.lastname: Yamanaka
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: murakami20040408@yahoo.co.jp.
authors.forename: Masato
authors.initials: M
authors.lastname: Murakami
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: yutakatanaka_circ@yahoo.co.jp.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tanaka
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: saeko@kamakuraheart.org.
authors.forename: Saeko
authors.initials: S
authors.lastname: Takahashi
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: akasaka-cba@umin.ac.jp.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Akasaka
authors.affiliation: Department of Cardiology and Catheterization, Laboratory and Cardiovascular R&D Center, Shonan Kamakura General Hospital, Kamakura, Japan. Electronic address: transradial@kamakuraheart.org.
authors.forename: Shigeru
authors.initials: S
authors.lastname: Saito
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D011150:Popliteal Artery / Q000000981:diagnostic imaging* / Q000601:surgery; D006435:Renal Dialysis / Q000009:adverse effects / Q000639:trends*; D012189:Retrospective Studies; D012307:Risk Factors; D000069322:Self Expandable Metallic Stents / Q000009:adverse effects / Q000639:trends*; D013997:Time Factors; D014654:Vascular Patency / Q000502:physiology*
chemical_list: D000497:Alloys; D008670:Metals; C013616:nitinol
keywords: Bare-self expandable nitinol stent; Femoropopliteal; Long-term results; Patency