title: [THE COURSE OF TUBERCULOSIS AND ITS TREATMENT EFFICIENCY IN PATIENTS WITH LATE-STAGE HIV INFECTION].
abstract: The course of tuberculosis and efficiency of combination antituberculous and antiretroviral therapy were analyzed in 30 patients with late-stage HIV infection. The acute progressive course of tuberculosis was found to reduce the role of prophylactic fluorographic examination in this category of patients. Various diagnostic mini-invasive surgical procedures proved to be of great informative value (91.7% sensitivity) in the diagnosis of atypical tuberculosis. During the intensive phase, combination antituberculous and antiviral therapy with its high adherence yielded good clinical results: the median CD4 lymphocyte increase was 65 cells/µl; the therapy was acknowledged to be effective in treating the tuberculous process in 76.7% of the patients; mortality was 6.7%.
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count / Q000379:methods; D060085:Coinfection / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D008297:Male; D062072:Patient Acuity; D012426:Russia / Q000453:epidemiology; D016896:Treatment Outcome; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D019380:Anti-HIV Agents; D000995:Antitubercular Agents