title: A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation.
abstract: Carbon nanotube (CNT) nanoporous membranes based on pre-aligned CNTs have superior nano-transportation properties in biological science. Herein, we report a smart temperature- and temperature-magnetic-responsive CNT nanoporous membrane (CNM) by grafting thermal-sensitive poly(N-isopropylacrylamide) (PNIPAM) and Fe3O4 nanoparticles (Fe3O4-NPs) on the open ends of pre-aligned CNTs with a diameter around 15 nm via surface-initiated atom transfer radical polymerization (SI-ATRP) method. The inner cavity of the modified CNTs in the membrane is designed to be the only path for ion and protein transportation, and its effective diameter with a variation from ~5.7 nm to ~12.4 nm can be reversible tuned by temperature and magnetic field. The PNIPAM modified CNM (PNIPAM-CNM) and PNIPAM magnetic nanoparticles modified CNM (PNIPAM-MAG-CNM) exhibit excellent temperature- or temperature-magnetic-responsive gating property to separate proteins of different sizes. The PNIPAM-CNMs and PNIPAM-MAG-CNMs have potential applications in making artificial cells, biosensors, bioseparation and purification filters.
authors.affiliation: Laboratory for New Fiber Materials and Modern Textile, Growing Base for State Key Laboratory, College of Materials Science &Engineering, Qingdao University, Qingdao 266071, China.
authors.forename: Hailin
authors.initials: H
authors.lastname: Cong
authors.affiliation: Laboratory for New Fiber Materials and Modern Textile, Growing Base for State Key Laboratory, College of Materials Science &Engineering, Qingdao University, Qingdao 266071, China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Xu
authors.affiliation: Laboratory for New Fiber Materials and Modern Textile, Growing Base for State Key Laboratory, College of Materials Science &Engineering, Qingdao University, Qingdao 266071, China.|College of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Yu
authors.affiliation: Center for Soft Condensed Matter Physics and Interdisciplinary Research, Soochow University, Suzhou 215006, China.
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Laboratory for New Fiber Materials and Modern Textile, Growing Base for State Key Laboratory, College of Materials Science &Engineering, Qingdao University, Qingdao 266071, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D000818:Animals; D002417:Cattle; D052203:Ferrosoferric Oxide / Q000737:chemistry; D007477:Ions / Q000737:chemistry / Q000378:metabolism; D060526:Magnetic Fields; D058185:Magnetite Nanoparticles / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D009211:Myoglobin / Q000737:chemistry / Q000378:metabolism; D037742:Nanotubes, Carbon / Q000737:chemistry*; D016062:Porosity; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*; D012710:Serum Albumin, Bovine / Q000737:chemistry / Q000378:metabolism; D013499:Surface Properties; D013696:Temperature
chemical_list: D000180:Acrylic Resins; D007477:Ions; D058185:Magnetite Nanoparticles; D009211:Myoglobin; D037742:Nanotubes, Carbon; D011506:Proteins; C052970:poly-N-isopropylacrylamide; D012710:Serum Albumin, Bovine; D052203:Ferrosoferric Oxide