title: Caruncular and Pericaruncular Sebaceous Gland Hyperplasia: A Report of 2 Cases and Literature Review.
abstract: OBJECTIVE
  To report the clinical and histopathological features of two patients with caruncular and pericaruncular sebaceous gland hyperplasia (SGH) with a literature review.
  
  
  METHODS
  We performed a retrospective pathology database search of 1195 ophthalmic specimens receiving the clinical diagnosis of SGH for caruncular/pericaruncular lesions during 2004 to 2014 at Tokyo Dental College, Ichikawa General Hospital. Paraffin sections were stained with hematoxylin and eosin. A retrospective patient record and literature review was also performed.
  
  
  RESULTS
  Database search disclosed 2 male patients with SGH of 1195 specimens (0.15%). Pathological specimens revealed neither any cellular/nuclear atypia nor any mitotic figures and invasive features. No recurrences were observed in these 2 cases 12 to 18 months after excision.
  
  
  CONCLUSIONS
  Caruncle and pericaruncular SGH is an uncommon lesion which needs careful histopathological evaluation for differentiation especially from caruncular neoplasias.
authors.affiliation: Department of Ophthalmology (M.O., M.S., M.D., J.S.), Tokyo Dental College Ichikawa General Hospital, Chiba, Japan; Department of Ophthalmology (M.O., M.D., K.T.), Keio University School of Medicine, Tokyo, Japan; Department of Ophthalmology (M.S.), Fukushima University School of Medicine, Fukushima, Japan; Department of Pathology and Laboratory Medicine (J.M., Y.T.), Tokyo Dental College Ichikawa General Hospital, Chiba, Japan; and Department of Ophthalmology (H.O.), Jichi Medical University, Saitama, Japan.
authors.forename: Mamoru
authors.initials: M
authors.lastname: Ogawa
authors.forename: Megumi
authors.initials: M
authors.lastname: Shinzawa
authors.forename: Murat
authors.initials: M
authors.lastname: Dogru
authors.forename: Jun
authors.initials: J
authors.lastname: Miyauchi
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Yoko
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Hiroto
authors.initials: H
authors.lastname: Obata
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsubota
authors.forename: Jun
authors.initials: J
authors.lastname: Shimazaki
mesh_terms: D000328:Adult; D001706:Biopsy; D019882:Blepharoplasty; D003937:Diagnosis, Differential; D005141:Eyelid Diseases / Q000473:pathology* / Q000601:surgery; D005143:Eyelids / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008297:Male; D008537:Meibomian Glands / Q000473:pathology*; D008875:Middle Aged