title: Translation, cross-cultural adaptation, and validation of the french version of the 15-item Myasthenia Gravis Quality Of life scale.
abstract: Evaluation of quality of life (QOL) has become essential in healthcare. Currently no MG-specific QOL measure exists in French. The aim of this study was to translate, culturally adapt, and evaluate the psychometric properties of the French version of the 15-Item Myasthenia Gravis Quality of Life Scale (MG-QOL15) scale for French myasthenia patients.
  
  
  
  Translation and cross-cultural adaption of the MG-QOL15 was performed, followed by reliability and validity evaluations.
  
  
  
  One hundred and twenty-five patients were included. Internal consistency was excellent (Cronbach α = 0.92) as was test-retest reliability (ICC = 0.92, 95% CI 0.86-0.96). Concurrent validity was good for both clinical scores (myasthenic muscle score: ρ = -0.52, P < 0.001; Myasthenia Gravis-Activities of Daily Living scale score: ρ = 0.62, P < 0.001). Correlations were strongest for overall QOL (ρ = 0.62, P < 0.001) and physical health (ρ = 0.67, P < 0.001) on the World Health Organization Quality of Life short score (WHO-QOL BREF).
  
  
  
  The French version of the MG-QOL15 is valid and reliable and is now available for use with French-speaking patients. Muscle Nerve, 2016 Muscle Nerve 55: 639-645, 2017.
authors.affiliation: Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hopitaux de Paris (APHP), 75651, Paris Cedex 13, France.|Bioingénierie, Tissus et Neuroplasticité-EA 7377, Université Paris-Est, Créteil, France.
authors.forename: Simone
authors.initials: S
authors.lastname: Birnbaum
authors.affiliation: Unité de Recherche Clinique Paris Ile de France Ouest, Hôpital Ambroise Paré, APHP, Boulogne Billancourt, France.
authors.forename: Idir
authors.initials: I
authors.lastname: Ghout
authors.affiliation: Réanimation Neurologique, Groupe Hospitalier Pitié-Salpêtrière, APHP, Paris, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Demeret
authors.affiliation: Réanimation Neurologique, Groupe Hospitalier Pitié-Salpêtrière, APHP, Paris, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Bolgert
authors.affiliation: Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hopitaux de Paris (APHP), 75651, Paris Cedex 13, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Eymard
authors.affiliation: Service de réanimation médicale, Hôpital Raymond-Poincaré, APHP, Garches, France.
authors.forename: Tarek
authors.initials: T
authors.lastname: Sharshar
authors.affiliation: Bioingénierie, Tissus et Neuroplasticité-EA 7377, Université Paris-Est, Créteil, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Portero
authors.affiliation: Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hopitaux de Paris (APHP), 75651, Paris Cedex 13, France.
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Hogrel
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology*; D000328:Adult; D000368:Aged; D003431:Cross-Cultural Comparison; D005260:Female; D005602:France; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000523:psychology*; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D014177:Translations
keywords: autoimmune myasthenia gravis; cultural adaptation; patient-reported outcome measure; quality of life; validation