title: Effects of bipyramidal gold nanoparticles and gold nanorods on the detection of immunoglobulins.
abstract: Two types of gold nanoparticles are compared for their use in a sensor for immunoglobulin detection - bipyramidal gold nanoparticles (GBPs) and gold nanorods (GNRs). Using surface plasmon resonance spectroscopy and square wave voltammetry allowed us to evaluate the utilities of these two types of gold nanoparticles in a label-free detection of the analyte IgG. However both systems showed a significant enhancement in sensitivity over a nanoparticle free system, showing a 64-fold enhancement for the GBP-containing sensor and a 16-fold enhancement for the GNR-containing sensor systems.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, PR China and Department of Physical and Environmental Sciences, University of Toronto Scarborough, TorontoM1C 1A4, Canada and Department of Chemistry, University of Toronto, TorontoM5S 2J7, Canada. bernie.kraatz@utoronto.ca.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, TorontoM1C 1A4, Canada and Department of Chemistry, University of Toronto, TorontoM5S 2J7, Canada. bernie.kraatz@utoronto.ca.
authors.forename: Zhe
authors.initials: Z
authors.lastname: She
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, TorontoM1C 1A4, Canada and Department of Chemistry, University of Toronto, TorontoM5S 2J7, Canada. bernie.kraatz@utoronto.ca.
authors.forename: Han
authors.initials: H
authors.lastname: Su
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, TorontoM1C 1A4, Canada and Department of Chemistry, University of Toronto, TorontoM5S 2J7, Canada. bernie.kraatz@utoronto.ca.
authors.forename: Kagan
authors.initials: K
authors.lastname: Kerman
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, TorontoM1C 1A4, Canada and Department of Chemistry, University of Toronto, TorontoM5S 2J7, Canada. bernie.kraatz@utoronto.ca.
authors.forename: Heinz-Bernhard
authors.initials: HB
authors.lastname: Kraatz
mesh_terms: D015374:Biosensing Techniques; D006046:Gold; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D053768:Metal Nanoparticles; D043942:Nanotubes; D020349:Surface Plasmon Resonance
chemical_list: D007136:Immunoglobulins; D006046:Gold