title: Advanced Interventional Therapy for Radiation-Induced Cardiovascular Disease.
abstract: This report describes the case of a 61-year-old woman who presented with dyspnea, aortic stenosis, and coronary artery disease-typical side effects of radiation therapy for Hodgkin lymphoma. A poor candidate for surgery, she underwent successful high-risk percutaneous coronary intervention and subsequent transcatheter aortic valve replacement. This report highlights some of the cardiovascular-specific sequelae of radiation therapy for cancer treatment; in addition, possible directions for future investigations are discussed.
authors.forename: Daisy C
authors.initials: DC
authors.lastname: Nieto
mesh_terms: D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D054855:Drug-Eluting Stents; D018618:Echocardiography, Doppler, Color; D005260:Female; D006350:Heart Valve Prosthesis; D006689:Hodgkin Disease / Q000175:diagnosis / Q000532:radiotherapy*; D006801:Humans; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000295:instrumentation; D011832:Radiation Injuries / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D011878:Radiotherapy / Q000009:adverse effects; D012720:Severity of Illness Index; D017741:Survivors; D065467:Transcatheter Aortic Valve Replacement / Q000295:instrumentation; D016896:Treatment Outcome
keywords: Aortic valve insufficiency/therapy; Hodgkin disease/radiotherapy; coronary artery disease/prevention & control; heart valve prosthesis implantation/methods; heart/radiation effects; radiation injuries/etiology/prevention & control; radiotherapy/adverse effects; treatment outcome