title: [How to consider triggers and comorbid conditions in severe asthma in adults].
abstract: Triggers and precipitating factors as well as comorbid conditions are associated with asthma and severe asthma. They interfere with the potential to control the disease and represent an additional burden for the patients. Allergen exposure is well known to induce loss of control and exacerbations. Comorbid conditions belong to various fields of medicines including cardiovascular diseases, osteoporosis, obesity and sleep apneas and GERD. They should be diagnosed and treated for themselves according to the best state of the art. Their precise role et their contribution to severe asthma pathophysiology is largely unknown and longitudinal cohort studies are needed to better understand and treat the patients with severe asthma.
authors.affiliation: Hôpitaux universitaires de Strasbourg, département de pneumologie, 67000 Strasbourg, France.
authors.forename: Cindy
authors.initials: C
authors.lastname: Barnig
authors.affiliation: Université Claude-Bernard Lyon 1, hôpital de la Croix-Rousse, service de pneumologie, HCL, CIRI Inserm U1111, 69001 Lyon, France.
authors.forename: Martin
authors.initials: M
authors.lastname: Veaudor
authors.affiliation: AP-HM, Aix-Marseille université, département des maladies respiratoires, UMR 7333 CNRS, Inserm U1067, 13015 Marseille, France.
authors.forename: Clarisse
authors.initials: C
authors.lastname: Gautier
authors.affiliation: Université Claude-Bernard Lyon 1, hôpital de la Croix-Rousse, service de pneumologie, HCL, CIRI Inserm U1111, 69001 Lyon, France.
authors.forename: Victor
authors.initials: V
authors.lastname: Margelidon-Cozzolino
authors.affiliation: 3, rue Cronstadt, 06000 Nice, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Pigearias
authors.affiliation: Université Claude-Bernard Lyon 1, hôpital de la Croix-Rousse, service de pneumologie, HCL, CIRI Inserm U1111, 69001 Lyon, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Devouassoux
authors.affiliation: CHU de Bordeaux, université de Bordeaux, service des maladies respiratoires, ISPED, U897, 33000 Bordeaux, France.
authors.forename: Chantal
authors.initials: C
authors.lastname: Raherison
authors.affiliation: Hôpitaux universitaires de Strasbourg, département de pneumologie, 67000 Strasbourg, France.
authors.forename: Frederic
authors.initials: F
authors.lastname: De Blay
authors.affiliation: AP-HM, Aix-Marseille université, département des maladies respiratoires, UMR 7333 CNRS, Inserm U1067, 13015 Marseille, France. Electronic address: pascal.chanez@univ-amu.fr.
authors.forename: Pascal
authors.initials: P
authors.lastname: Chanez
mesh_terms: D000328:Adult; D001249:Asthma / Q000453:epidemiology* / Q000209:etiology*; D015897:Comorbidity; D006801:Humans; D012130:Respiratory Hypersensitivity / Q000150:complications / Q000453:epidemiology; D012307:Risk Factors