title: Bone Marrow Derived Eosinophil Cultures.
abstract: Eosinophils are multifunctional effector cells implicated in the pathogenesis of a variety of diseases including asthma, eosinophil gastrointestinal disorders and helminth infection. Mouse bone marrow derived progenitor cells can be differentiated into eosinophils following IL-5 exposure. These bone marrow derived eosinophils are fully differentiated at the end of a 14 day culture based on morphology and expression of molecular markers.
authors.affiliation: Division of Pediatrics, Cincinnati Children's Hospital Medical Center/University of Cincinnati, Cincinnati, USA.
authors.forename: Thomas X
authors.initials: TX
authors.lastname: Lu
authors.affiliation: Division of Pediatrics, Cincinnati Children's Hospital Medical Center/University of Cincinnati, Cincinnati, USA.
authors.forename: Marc E
authors.initials: ME
authors.lastname: Rothenberg