title: Do not throw the baby out with the bath water: a guide for using non-significant results in practice.
abstract: Acting on results that are not statistically significant is challenging for clinicians. Such results are often interpreted as evidence of lack of association or as useless evidence. We provide a framework for interpreting and applying non-significant results at the point of care using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.
authors.affiliation: Evidence-based Practice Center, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Mouaffaa
authors.initials: M
authors.lastname: Tello
authors.affiliation: Evidence-based Practice Center, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Feras
authors.initials: F
authors.lastname: Zaiem
authors.affiliation: Evidence-based Practice Center, Mayo Clinic, Rochester, Minnesota, USA Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Mary Catherine
authors.initials: MC
authors.lastname: Tolcher
authors.affiliation: Evidence-based Practice Center, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Mohammad Hassan
authors.initials: MH
authors.lastname: Murad
mesh_terms: D019317:Evidence-Based Medicine; D017410:Practice Guidelines as Topic
keywords: EDUCATION & TRAINING (see Medical Education & Training); EPIDEMIOLOGY; OBSTETRICS