title: A rare case of Ganglioneuroblastoma Encapsulated in Pheochromocytoma.
abstract: Pheochromocytoma and Ganglioneuroblastoma are separate diseases and a rare combination in which the diagnosis can only be confirmed by pathological examination after tumor excision. We reported here a case of ganglioneuroblastoma encapsulated in pheochromocytoma. The patient is a woman, 73 years old, hypertensive, with hypothyroidism, associated for 15 years with hypercholesterolemia and hypertriglyceridemia, which had frequent complaints of low back pain. She underwent magnetic resonance and the findings were consistent with the diagnosis of pheochromocytoma. After surgery, anatomic, pathologic and immunohistochemistry analysis confirmed the diagnosis of pheochromocytoma composed by small ganglioneuroblastoma representation with the identification of small focus of infiltration of the adrenal capsule and adipose tissue by pheochromocytoma. This rare association can instigate the discussion of methods of diagnosis, more effective and more appropriate treatments for each patient.
authors.affiliation: Faculdade de Medicina de Itajubá, Av. Renó Júnior, 368 - São Vicente, Itajubá, MG, Brazil. nathaliavieira100@hotmail.com.
authors.forename: Nathália Vieira
authors.initials: NV
authors.lastname: Sousa
authors.affiliation: Faculdade de Medicina de Itajubá, Av. Renó Júnior, 368 - São Vicente, Itajubá, MG, Brazil.
authors.forename: Luísa Coelho
authors.initials: LC
authors.lastname: Marques de Oliveira
authors.affiliation: Faculdade de Medicina de Itajubá, Av. Renó Júnior, 368 - São Vicente, Itajubá, MG, Brazil.
authors.forename: Paulo José Oliveira
authors.initials: PJ
authors.lastname: Cortez
authors.affiliation: Programa de Pós-Graduação em Fisioterapia, Faculdade de Ciências e Tecnologia, UNESP, Rua Roberto Simonsen, 305, Presidente Prudente, SP, Brazil.
authors.forename: Vitor Engrácia
authors.initials: VE
authors.lastname: Valenti
authors.affiliation: Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom.
authors.forename: David Mathew
authors.initials: DM
authors.lastname: Garner
authors.affiliation: Faculdade de Medicina de Itajubá, Av. Renó Júnior, 368 - São Vicente, Itajubá, MG, Brazil.
authors.forename: Roseane de Souza Candido
authors.initials: Rde S
authors.lastname: Irulegui
authors.affiliation: Faculdade de Medicina de Itajubá, Av. Renó Júnior, 368 - São Vicente, Itajubá, MG, Brazil.|Instituto Dante Pazzanese de Cardiologia, Av. Dr. Dante Pazzanese, 500, São Paulo, SP, Brazil.
authors.forename: Dalmo Antônio Ribeiro
authors.initials: DA
authors.lastname: Moreira
mesh_terms: D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology; D000368:Aged; D002395:Catecholamines / Q000652:urine; D003937:Diagnosis, Differential; D005260:Female; D018305:Ganglioneuroblastoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010673:Pheochromocytoma / Q000000981:diagnostic imaging / Q000473:pathology*; D011877:Radionuclide Imaging; D035583:Rare Diseases
chemical_list: D002395:Catecholamines; D019797:3-Iodobenzylguanidine
keywords: Abdominal Neoplasms; Ganglioneuroblastoma; Pheochromocytoma