title: Inflammatory Cutaneous Diseases in Renal Transplant Recipients.
abstract: Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relative incidence and characteristics of inflammatory skin diseases in this type of patient. In this study, we analyze the incidence of a number of inflammatory cutaneous diseases in a cohort of patients who underwent kidney transplantation. Although our study shows a relatively low incidence of these pathologies in transplanted patients-in agreement with the general action of immunosuppressant therapies in reducing inflammation-we scored a different efficacy of the various immunosuppressive regimens on inflammatory and autoimmune skin diseases. This information can be key for designing immunosuppressive regimens and devising accurate follow-up protocols.
authors.affiliation: Department of Health Sciences, "A. Avogadro" University of Eastern Piedmont, 28100 Novara, Italy. paola.savoia@med.uniupo.it.
authors.forename: Paola
authors.initials: P
authors.lastname: Savoia
authors.affiliation: Department of Medical Science, University of Turin, 10126 Turin, Italy. g.cavali_dr@yahoo.it.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cavaliere
authors.affiliation: Department of Health Sciences, "A. Avogadro" University of Eastern Piedmont, 28100 Novara, Italy. elisa.zavattaro@med.uniupo.it.
authors.forename: Elisa
authors.initials: E
authors.lastname: Zavattaro
authors.affiliation: Department of Health Sciences, "A. Avogadro" University of Eastern Piedmont, 28100 Novara, Italy. federica.veronese@med.uniupo.it.
authors.forename: Federica
authors.initials: F
authors.lastname: Veronese
authors.affiliation: Department of Medical Science, University of Turin, 10126 Turin, Italy. fava_paolo@yahoo.it.
authors.forename: Paolo
authors.initials: P
authors.lastname: Fava
mesh_terms: D000068338:Everolimus / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007249:Inflammation / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000276:immunology; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D020123:Sirolimus / Q000627:therapeutic use; D012871:Skin Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D066027:Transplant Recipients
chemical_list: D007166:Immunosuppressive Agents; D000068338:Everolimus; D020123:Sirolimus
keywords: cutaneous diseases; inflammatory; kidney transplantation