title: Association of Psychological Characteristics and Functional Dyspepsia Treatment Outcome: A Case-Control Study.
abstract: This study was to investigate the association of psychological characteristics and functional dyspepsia treatment outcome. 109 patients who met the criteria for FD were enrolled. Eysenck Personality Questionnaire (EPQ), Symptom Checklist 90 (SCL90), and the Pittsburgh Sleep Quality Index (PSQI) were used to measure personality, psychological symptoms, and sleep quality in our patients. Leeds Dyspepsia Questionnaire (LDQ) was used to assess dyspeptic symptoms at baseline and after eight weeks of treatment. The LDQ scores change after therapy, and the degraded rate of LDQ was used to assess the prognosis of patients. Logistic regression model was used to assess the effect of the personality, psychological symptoms, and sleep quality on the prognosis of patients. Our result revealed that poor sleep quality (OR = 7.68, 95% CI 1.83-32.25) and bad marriage status (OR = 1.22, 95% CI 1.10-1.36) had the negative effect on the prognosis of FD, while extroversion in personality traits (OR = 0.86, 95% CI 0.76-0.96) had positive effect on the prognosis of FD. We should pay attention to the sleep quality, the personality, and the marriage status of FD patients; psychological intervention may have benefit in refractory FD.
authors.affiliation: Department of Psychiatry, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Yiping
authors.identifier: 0000-0003-3602-5165
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Gastroenterology, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Caihua
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Epidemiology, Shandong University School of Public Health, Jinan, Shandong 250012, China.
authors.forename: Jinyu
authors.identifier: 0000-0002-7581-4928
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Psychiatry, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Leilei
authors.identifier: 0000-0003-1631-5683
authors.initials: L
authors.lastname: Zheng
authors.affiliation: Department of Psychiatry, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Weibo
authors.identifier: 0000-0003-3742-8265
authors.initials: W
authors.lastname: Liu
authors.affiliation: Department of Psychiatry, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Huichun
authors.identifier: 0000-0001-5868-1310
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Psychiatry, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Shaohua
authors.identifier: 0000-0003-1017-4824
authors.initials: S
authors.lastname: Yu
authors.affiliation: Department of Psychiatry, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Bin
authors.identifier: 0000-0001-5569-4984
authors.initials: B
authors.lastname: Pan
authors.affiliation: Department of Psychiatry, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Hualiang
authors.identifier: 0000-0001-5126-5218
authors.initials: H
authors.lastname: Yu
authors.affiliation: Department of Radiology, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, China.
authors.forename: Risheng
authors.identifier: 0000-0003-3424-8429
authors.initials: R
authors.lastname: Yu