title: DNA Polymerase θ: Duct Tape and Zip Ties for a Fragile Genome.
abstract: Using a combination of genetics and cellular DNA rejoining assays, in this issue of Molecular Cell, Wyatt et al. (2016) demonstrate a critical role for mammalian DNA polymerase θ in the rejoining of DNA ends that are poor substrates for classical non-homologous end joining.
authors.affiliation: Department of Medicine, Division of Hematology-Oncology and Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Willis
authors.affiliation: Department of Medicine, Division of Hematology-Oncology and Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA. Electronic address: rscully@bidmc.harvard.edu.
authors.forename: Ralph
authors.initials: R
authors.lastname: Scully
mesh_terms: D000818:Animals; D004247:DNA / Q000235:genetics; D059766:DNA End-Joining Repair; D004260:DNA Repair; D004259:DNA-Directed DNA Polymerase / Q000235:genetics*; D006801:Humans; D000097462:DNA Polymerase theta
chemical_list: D004247:DNA; D004259:DNA-Directed DNA Polymerase; D000097462:DNA Polymerase theta