title: Drug Delivery by Controlling a Supramolecular Host-Guest Assembly with a Reversible Photoswitch.
abstract: The reversibly switchable trans-chalcone/flavylium photochromic system was successfully coupled to the complexation equilibrium of a drug-cucurbit[7]uril host-guest assembly. Hence, the phototriggered release of memantine under illumination at 366 nm was observed. The process can be partially reverted through a thermally activated back reaction.
authors.affiliation: Laboratório Associado para a Química Verde (LAQV), Rede de Química e Tecnologia (REQUIMTE), Departmento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal. nuno.basilio@fct.unl.pt.
authors.forename: Nuno
authors.initials: N
authors.lastname: Basílio
authors.affiliation: CIQSO - Center for Research in Sustainable Chemistry and, Department of Chemistry, University of Huelva, Campus de El Carmen s/n, 21071, Huelva, Spain. uwe.pischel@diq.uhu.es.
authors.forename: Uwe
authors.identifier: http://orcid.org/0000-0001-8893-9829
authors.initials: U
authors.lastname: Pischel
keywords: cucurbiturils; drug delivery; flavylium; host-guest chemistry; photochemistry