title: Low Volume Aerobic Training Heightens Muscle Deoxygenation in Early Post-Angina Pectoris Patients.
abstract: The aim of this study was to investigate the effect of low volume aerobic exercise training on muscle O2 dynamics during exercise in early post-angina pectoris (AP) patients, as a pilot study. Seven AP patients (age: 72 ± 6 years) participated in aerobic exercise training for 12 weeks. Training consisted of continuous cycling exercise for 30 min at the individual's estimated lactate threshold, and the subjects trained for 15 ± 5 exercise sessions over 12 weeks. Before and after training, the subjects performed ramp cycling exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆Deoxy-Hb) and total hemoglobin concentration (∆Total-Hb) were monitored at the vastus lateralis by near infrared spatial resolved spectroscopy during exercise. The SmO2 was significantly lower and ∆Deoxy-Hb was significantly higher after training than before training, while there were no significant changes in ∆Total-Hb. These results indicated that muscle deoxygenation and muscle O2 extraction were potentially heightened by aerobic exercise training in AP patients, even though the exercise training volume was low.
authors.affiliation: Faculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan. stakagi@aoni.waseda.jp.|Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan. stakagi@aoni.waseda.jp.
authors.forename: Shun
authors.initials: S
authors.lastname: Takagi
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Murase
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Ryotaro
authors.initials: R
authors.lastname: Kime
authors.affiliation: Department of Electrical and Electronic Engineering, Shizuoka University, Hamamatsu, Shizuoka, Japan.
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Niwayama
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Osada
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Toshihito
authors.initials: T
authors.lastname: Katsumura
mesh_terms: D000368:Aged; D015308:Anaerobic Threshold; D000787:Angina Pectoris / Q000097:blood / Q000503:physiopathology / Q000601:surgery*; D001642:Bicycling; D001026:Coronary Artery Bypass; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D009119:Muscle Contraction; D010092:Oximetry / Q000379:methods; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption; D010865:Pilot Projects; D052097:Quadriceps Muscle / Q000378:metabolism* / Q000503:physiopathology; D019265:Spectroscopy, Near-Infrared; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D006454:Hemoglobins; C100003:deoxyhemoglobin; D010100:Oxygen
keywords: Cycling training; Ischemic heart disease; Muscle O2 dynamics; Near infrared spectroscopy; Peak aerobic capacity