title: Isolated sciatic neuropathy as an initial manifestation of a high grade B-cell lymphoma: A case report and literature review.
abstract: Sciatic nerve neuropathy due to infiltrating of a high grade B-cell lymphoma is a very rare situation and has not often been reported. We report a case with a previous history of indolent lymphoma who presented with isolated sciatic nerve neuropathy and was found to have diffuse large B cell lymphoma involving the sciatic nerve. Although the current case is not a primary sciatic nerve lymphoma given the systematic involvement shown on MRI and PET/CT scan, the case represents a neurolymphomatosis of the sciatic nerve given the direct invasion of the lymphoma cells into the sciatic nerve. Due to the rarity of this condition, we subsequently reviewed related literatures.
authors.affiliation: Department of Neurology, Penn State Hershey Medical Center, PA 17033, United States. Electronic address: wenzhuanhe@yahoo.com.
authors.forename: Wenzhuan
authors.initials: W
authors.lastname: He
authors.affiliation: Department of Neurology, New Jersey Medical School, Newark, NJ 07101, United States. Electronic address: wangpgy1@gmail.com.
authors.forename: Weizhen
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Radiology, Penn State Hershey Medical Center, PA 17033, United States. Electronic address: cgustas@hmc.psu.edu.
authors.forename: Cristy
authors.initials: C
authors.lastname: Gustas
authors.affiliation: Department of Pathology, Penn State Hershey Medical Center, PA 17033, United States. Electronic address: jmalysz@hmc.psu.edu.
authors.forename: Jozef
authors.initials: J
authors.lastname: Malysz
authors.affiliation: Department of Neurology, Penn State Hershey Medical Center, PA 17033, United States. Electronic address: dkaur@hmc.psu.edu.
authors.forename: Divpreet
authors.initials: D
authors.lastname: Kaur
mesh_terms: D000818:Animals; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis; D020426:Sciatic Neuropathy / Q000175:diagnosis / Q000209:etiology*
keywords: Isolated sciatic neuropathy; Lymphoma; Neurolymphomatosis