title: Ultrasound-Guided Abrams Pleural Biopsy vs CT-Guided Tru-Cut Pleural Biopsy in Malignant Pleural Disease, a 3-Year Follow-up Study.
abstract: Conventional Abrams biopsy shows low sensitivity in suspected malignant pleural disease. There are limited data on the improvement in sensitivity by adding in image guidance. This retrospective study compares the diagnostic sensitivity of Abrams biopsy using ultrasound guidance with CT-guided Tru-Cut biopsy in suspected malignant pleural disease.
  
  
  
  Data were collected from 2006 to 2012 of patients who underwent image-guided biopsies for suspected non-tuberculous pleural disease. Data were collected on the result of the initial biopsy and final patient diagnosis as of June 2015.
  
  
  
  Sixty-three patients underwent image-guided Abrams biopsy and 29 underwent CT-guided Tru-Cut biopsies. The sensitivity of Abrams was 71.43 % compared to 75 % in the CT-guided Tru-Cut group. Specificity was 100 % in both groups.
  
  
  
  Image-guided Abrams biopsies demonstrate comparable diagnostic sensitivity in malignant pleural disease to CT-guided Tru-Cut biopsy.
authors.affiliation: Kings College London, London, WC2R 2LS, UK. deepan.sivakumar@kcl.ac.uk.
authors.forename: Parthipan
authors.identifier: 0000-0003-3740-2612
authors.initials: P
authors.lastname: Sivakumar
authors.affiliation: East Surrey Hospital, Redhill, RH1 5RH, UK.
authors.forename: Deepak
authors.initials: D
authors.lastname: Jayaram
authors.affiliation: Princess Royal University Hospital, Orpington, UK.
authors.forename: Deepak
authors.initials: D
authors.lastname: Rao
authors.affiliation: Kings College London, London, WC2R 2LS, UK.
authors.forename: Vignesh
authors.initials: V
authors.lastname: Dhileepan
authors.affiliation: Guy's and St Thomas' NHS Foundation Trust, London, UK.
authors.forename: Irfan
authors.initials: I
authors.lastname: Ahmed
authors.affiliation: Guy's and St Thomas' NHS Foundation Trust, London, UK.
authors.forename: Liju
authors.initials: L
authors.lastname: Ahmed
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D008297:Male; D008875:Middle Aged; D010994:Pleura / Q000000981:diagnostic imaging* / Q000473:pathology*; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
keywords: Abrams; Biopsy; Malignancy; Pleura; Tru-Cut