title: Human Immunodeficiency Virus (HIV)-Infected Patients Accept Finger Stick Blood Collection for Point-Of-Care CD4 Testing.
abstract: BACKGROUND
  HIV-infected patients require antiretroviral treatment for life. To improve access to care, CD4 enumeration and viral load tests have been redesigned to be used as point-of-care techniques using finger-stick blood. Accurate CD4 counting in capillary blood requires a free flowing blood drop that is achieved by blade incision. The aim of this study was to assess the attitude of the patients toward blade-based finger-stick blood donation.
  
  
  METHODS
  Four hundred and ninety-nine patients were included (299 patients from South Africa and 200 from Belgium). They completed a questionnaire to express their preference for finger stick or venipuncture, after undergoing both. The South African patient cohort was divided in two groups, receiving either single or multiple finger stick for CD4 and other HIV-related tests. The Belgian patients received a single finger stick for CD4 testing, and were asked to respond directly and again after two days.
  
  
  RESULTS
  The majority of the patients preferred the finger stick to the venipuncture. The perceived pain using the blade was superior to a small needle, but similar to a large needle. They preferred up to three finger sticks over one venipuncture. Up to 30% of the patients changed their mind over two days. The main reason for choosing a finger stick was continued bleeding after venipuncture. The most cited objection to finger stick was pain/soreness.
  
  
  CONCLUSIONS
  Patient perceptions support the implementation of donating capillary blood with blade-based finger stick during CD4 point-of-care testing.
authors.affiliation: Immunology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
authors.forename: Géraldine
authors.initials: G
authors.lastname: Daneau
authors.affiliation: Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
authors.forename: Natasha
authors.initials: N
authors.lastname: Gous
authors.affiliation: Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
authors.forename: Lesley
authors.initials: L
authors.lastname: Scott
authors.affiliation: Department of Haematology, National Health Laboratory Services - Tshwane Academic Division and University of Pretoria, Pretoria, South Africa.
authors.forename: Joachim
authors.initials: J
authors.lastname: Potgieter
authors.affiliation: Immunology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.|Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
authors.forename: Luc
authors.initials: L
authors.lastname: Kestens
authors.affiliation: Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.|National Priority Program of the National Health Laboratory Service, Johannesburg, South Africa.
authors.forename: Wendy
authors.initials: W
authors.lastname: Stevens
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001530:Belgium / Q000453:epidemiology; D018791:CD4 Lymphocyte Count / Q000295:instrumentation / Q000379:methods; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000453:epidemiology / Q000821:virology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D000067716:Point-of-Care Testing; D013019:South Africa / Q000453:epidemiology; D011795:Surveys and Questionnaires; D055815:Young Adult