title: Quintuplets: 5 Cases of NEC. Are There Other Risk Factors?
abstract: OBJECTIVE
  To review a case of quintuplets with all babies developing necrotizing enterocolitis.
  
  
  METHODS
  A retrospective study of preterm quintuplets all developing necrotizing enterocolitis. Clinical outcomes were reviewed.
  
  
  RESULTS
  Quintuplets were born at 24 weeks gestation. Each baby developed NEC and was treated. One baby died. Currently the remaining 4 infants are on full enteral nutrition.
  
  
  CONCLUSIONS
  Further studies are needed to better understand this emerging population of multiple birth pregnancy and the frequency of NEC development.
authors.affiliation: a Surgery , University of Alabama at Birmingham , Birmingham , Alabama , USA.
authors.forename: Kavita
authors.initials: K
authors.lastname: Nadendla
authors.affiliation: b Department of Maternal Fetal Medicine , University of Alabama at Birmingham , Birmingham , Alabama , USA.
authors.forename: Amelia
authors.initials: A
authors.lastname: Sutton
authors.affiliation: c Pathology , Children's Hospital of Alabama , Birmingham , Alabama , USA.
authors.forename: David
authors.initials: D
authors.lastname: Kelly
authors.affiliation: d Gastroenterology and Surgery , University of Alabama at Birmingham , Birmingham , Alabama , USA.
authors.forename: Reed
authors.initials: R
authors.lastname: Dimmitt
authors.affiliation: a Surgery , University of Alabama at Birmingham , Birmingham , Alabama , USA.
authors.forename: Linda
authors.initials: L
authors.lastname: Wilkinson
authors.affiliation: e Surgery , University of Buffalo , Buffalo , New York , USA.
authors.forename: Carroll
authors.initials: C
authors.lastname: Harmon
authors.affiliation: a Surgery , University of Alabama at Birmingham , Birmingham , Alabama , USA.
authors.forename: Colin
authors.initials: C
authors.lastname: Martin
mesh_terms: D020345:Enterocolitis, Necrotizing / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007082:Ileum; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D047928:Premature Birth / Q000473:pathology*; D011811:Quintuplets; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors
keywords: Necrotizing enterocolitis; genetics; multiple birth pregnancies; prematurity