title: Role of LiCl in Generating Soluble Organozinc Reagents.
abstract: The sensitivity provided by fluorescence microscopy enabled the observation of surface intermediates in the synthesis of soluble organozinc reagents by direct insertion of alkyl iodides to commercial zinc powder. Five hypotheses were examined for the mechanistic role of lithium chloride in enabling this direct insertion. The data are consistent with lithium chloride solubilizing organozinc reagents from the surface of the zinc after oxidative addition.
authors.affiliation: Department of Chemistry, University of California , Irvine, California 92697-2025, United States.
authors.forename: Chao
authors.initials: C
authors.lastname: Feng
authors.affiliation: Department of Chemistry, University of California , Irvine, California 92697-2025, United States.
authors.forename: Drew W
authors.initials: DW
authors.lastname: Cunningham
authors.affiliation: Department of Chemistry, University of California , Irvine, California 92697-2025, United States.
authors.forename: Quinn T
authors.initials: QT
authors.lastname: Easter
authors.affiliation: Department of Chemistry, University of California , Irvine, California 92697-2025, United States.
authors.forename: Suzanne A
authors.initials: SA
authors.lastname: Blum