title: Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung disease.
authors.affiliation: Sapienza University of Rome, Department of Clinical and Molecular Medicine, Cardiology Unit, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Romaniello
authors.affiliation: Sapienza University of Rome, Department of Clinical Medicine, Clinical Immunology Unit-Scleroderma Center, Italy. Electronic address: antonietta_gigante@yahoo.it.
authors.forename: Antonietta
authors.initials: A
authors.lastname: Gigante
authors.affiliation: Sapienza University of Rome, Department of Public Health and Infectious Diseases, Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Di Paolo
authors.affiliation: Sapienza University of Rome, Department of Clinical Medicine, Clinical Immunology Unit-Scleroderma Center, Italy.
authors.forename: Gaia
authors.initials: G
authors.lastname: Tallerini
authors.affiliation: Sapienza University of Rome, Department of Clinical Medicine, Clinical Immunology Unit-Scleroderma Center, Italy.
authors.forename: Biagio
authors.initials: B
authors.lastname: Barbano
authors.affiliation: Sapienza University of Rome, Department of Emergency Medicine, Italy.
authors.forename: Daria
authors.initials: D
authors.lastname: Amoroso
authors.affiliation: Sapienza University of Rome, Department of Public Health and Infectious Diseases, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Palange
authors.affiliation: Sapienza University of Rome, Department of Clinical Medicine, Clinical Immunology Unit-Scleroderma Center, Italy.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Rosato
mesh_terms: D000328:Adult; D000077300:Bosentan; D018450:Disease Progression; D065128:Endothelin Receptor Antagonists / Q000008:administration & dosage / Q000009:adverse effects; D005080:Exercise Test / Q000187:drug effects / Q000379:methods; D005260:Female; D005385:Fingers; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D044022:Receptor, Endothelin A / Q000378:metabolism; D012129:Respiratory Function Tests / Q000379:methods; D012595:Scleroderma, Systemic / Q000150:complications / Q000188:drug therapy; D012883:Skin Ulcer / Q000209:etiology / Q000517:prevention & control; D013223:Statistics as Topic; D013449:Sulfonamides / Q000008:administration & dosage / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D065128:Endothelin Receptor Antagonists; D044022:Receptor, Endothelin A; D013449:Sulfonamides; D000077300:Bosentan
keywords: Cardiopulmonary exercise test; Endothelin receptor antagonists; Interstitial lung disease; Pulmonary arterial hypertension; Systemic sclerosis