title: An overview of cutaneous T cell lymphomas.
abstract: Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of extranodal non-Hodgkin's lymphomas that are characterized by a cutaneous infiltration of malignant monoclonal T lymphocytes. They typically afflict adults with a median age of 55 to 60 years, and the annual incidence is about 0.5 per 100,000. Mycosis fungoides, Sézary syndrome, and primary cutaneous peripheral T cell lymphomas not otherwise specified are the most important subtypes of CTCL. CTCL is a complicated concept in terms of etiopathogenesis, diagnosis, therapy, and prognosis. Herein, we summarize advances which have been achieved in these fields.
authors.affiliation: Taha Physicians' Building, Khoramshahr, Khuzestan Province, Iran.
authors.forename: Nooshin
authors.initials: N
authors.lastname: Bagherani
authors.affiliation: Department of Dermatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.
authors.forename: Bruce R
authors.initials: BR
authors.lastname: Smoller
keywords: Sézary syndrome; cutaneous T cell lymphoma; mycosis fungoides