title: [New challenges to the treatment of cervical intraepithelial neoplasia].
abstract: Due to the progress of intracavitary afterloading technology and dosage of brachytherapy, a similar dose distribution as that of cervical conization can be achieved and can be applied to the treatment of cervical intraepithelial neoplasia (CIN), it is called "afterloading conization" . Being adjusted the radioactive source movement and weight, low exposure doses to the ovary, endometrium and vagina can be assured. So a high quality of life after treatment could be maintained and overcomes the shortcomings of cervical conization and hysterectomy, such as anesthesia, bleeding, over or insufficient treatment, early ovarian ageing and operative complications.
authors.affiliation: Department of Gynecologic Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
authors.forename: J H
authors.initials: JH
authors.lastname: Sun
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D019092:Conization / Q000009:adverse effects; D004717:Endometrium / Q000528:radiation effects; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D010053:Ovary / Q000528:radiation effects; D011183:Postoperative Complications / Q000517:prevention & control; D011788:Quality of Life; D000069079:Radiation Exposure; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D014621:Vagina / Q000528:radiation effects; D002578:Uterine Cervical Dysplasia / Q000532:radiotherapy* / Q000601:surgery