title: Hybrid-fusion SPECT/CT systems in parathyroid adenoma: Technological improvements and added clinical diagnostic value.
abstract: Nuclear medicine traditionally employs planar and single photon emission computed tomography (SPECT) imaging techniques to depict the biodistribution of radiotracers for the diagnostic investigation of a range of disorders of endocrine gland function. The usefulness of combining functional information with anatomy derived from computed tomography (CT), magnetic resonance imaging (MRI), and high resolution ultrasound (US), has long been appreciated, either using visual side-by-side correlation, or software-based co-registration. The emergence of hybrid SPECT/CT camera technology now allows the simultaneous acquisition of combined multi-modality imaging, with seamless fusion of 3D volume datasets. Thus, it is not surprising that there is growing literature describing the many advantages that contemporary SPECT/CT technology brings to radionuclide investigation of endocrine disorders, showing potential advantages for the pre-operative locating of the parathyroid adenoma using a minimally invasive surgical approach, especially in the presence of ectopic glands and in multiglandular disease. In conclusion, hybrid SPECT/CT imaging has become an essential tool to ensure the most accurate diagnostic in the management of patients with hyperparathyroidism.
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, MI, USA; Nuclear Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
authors.forename: K K
authors.initials: KK
authors.lastname: Wong
authors.affiliation: Department of Nuclear Medicine, Radiology, Medical Physics, Clinical Pathology, Rovigo Hospital, Rovigo, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Chondrogiannis
authors.affiliation: Nuclear Medicine Department, Hospital Clinic, Barcelona University, Barcelona, Spain.
authors.forename: H
authors.initials: H
authors.lastname: Bowles
authors.affiliation: Nuclear Medicine Department, Hospital Clinic, Barcelona University, Barcelona, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Fuster
authors.affiliation: Nuclear Medicine Department, Hospital Clinic, Barcelona University, Barcelona, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Sánchez
authors.affiliation: Department of Nuclear Medicine, Radiology, Medical Physics, Clinical Pathology, Rovigo Hospital, Rovigo, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Rampin
authors.affiliation: Department of Nuclear Medicine, Radiology, Medical Physics, Clinical Pathology, Rovigo Hospital, Rovigo, Italy. Electronic address: rubello.domenico@azisanrovigo.it.
authors.forename: D
authors.initials: D
authors.lastname: Rubello
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging*; D006801:Humans; D064847:Multimodal Imaging; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
keywords: Adenoma de paratiroides; Fusion-hybrid imaging; Gammagrafía de paratiroides; Imagen de fusión híbrida; Parathyroid adenoma; Parathyroid scintigraphy; SPECT/CT; SPECT/TC