title: Transient Splenial Lesion of the Corpus Callosum Related to Migraine with Aura in a Pediatric Patient.
abstract: BACKGROUND
  Transient splenial lesions of the corpus callosum are rare radiological findings first described in association with epilepsy, antiepileptic drugs and viral encephalitis. However, subsequently more cases were described associated with diverse clinical conditions.
  
  
  METHODS
  We describe a 13-year-old girl suffering from migraine with aura presenting with headache, right-sided hemiparesis and encephalopathy. Brain magnetic resonance imaging revealed an ovoid lesion in the splenium of the corpus callosum. The patient's neurological symptoms resolved within 3 days without therapy and the lesion disappeared in follow up magnetic resonance images obtained 3 weeks after the onset of the symptoms.
  
  
  RESULTS
  Migraine with aura was considered to be the cause of the lesion. To our knowledge the present case is the first report of a pediatric patient with a diagnosis of migraine with aura presenting with hemiparesis and encephalopathy.
  
  
  CONCLUSIONS
  A diagnosis of transient lesion of the corpus callosum should be suspected in patients with migraine with aura presenting with hemiparesis and encephalopathy. A mild course and a good prognosis might be expected in the presence of a splenial lesion of the corpus callosum.
authors.affiliation: Department of Pediatric Neurology, Marmara University, İstanbul, Turkey. olcaymd@hotmail.com.
authors.forename: Olcay
authors.initials: O
authors.lastname: Ünver
authors.affiliation: Department of Pediatric Neurology, Marmara University, İstanbul, Turkey.
authors.forename: Büşra
authors.initials: B
authors.lastname: Kutlubay
authors.affiliation: Department of Pediatrics, Marmara University, İstanbul, Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Besci
authors.affiliation: Department of Radiology, Marmara University, İstanbul, Turkey.
authors.forename: Gazanfer
authors.initials: G
authors.lastname: Ekinci
authors.affiliation: Department of Radiology, Marmara University, İstanbul, Turkey.
authors.forename: Feyyaz
authors.initials: F
authors.lastname: Baltacıoğlu
authors.affiliation: Department of Radiology, Marmara University, İstanbul, Turkey.
authors.forename: Dilşad
authors.initials: D
authors.lastname: Türkdoğan
mesh_terms: D000293:Adolescent; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D003337:Corpus Callosum / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D020325:Migraine with Aura / Q000000981:diagnostic imaging*; D012075:Remission, Spontaneous
keywords: Corpus callosum; Encephalopathy; Hemiparesis; Migraine with aura; Transient splenial lesion