title: Thrombosis in Cancer: Research Priorities Identified by a National Cancer Institute/National Heart, Lung, and Blood Institute Strategic Working Group.
abstract: The risk for venous thromboembolism (VTE) is increased in cancer and particularly with chemotherapy, and it portends poorer survival among patients with cancer. However, many fundamental questions about cancer-associated VTE, or Trousseau syndrome, remain unanswered. This report summarizes the proceedings of a working group assembled by the NCI and NHLBI in August 2014 to explore the state of the science in cancer-associated VTE, identify clinically important research gaps, and develop consensus on priorities for future research. Representing a convergence of research priorities between the two NIH Institutes, the workshop addressed epidemiologic, basic science, clinical, and translational issues in cancer-associated VTE. Cancer Res; 76(13); 3671-5. ©2016 AACR.
authors.affiliation: Division of Hematology/Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
authors.forename: Nigel S
authors.initials: NS
authors.lastname: Key
authors.affiliation: Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Alok A
authors.initials: AA
authors.lastname: Khorana
authors.affiliation: Division of Hematology/Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. nigel_key@med.unc.edu.
authors.forename: Nigel
authors.initials: N
authors.lastname: Mackman
authors.affiliation: Department of Biomedical Engineering and Cell and Development Biology, Oregon Health and Science University, Portland, Orlando.
authors.forename: Owen J T
authors.initials: OJ
authors.lastname: McCarty
authors.affiliation: Blood Research Institute, Blood Center of Wisconsin, Department of Medicine, Biochemistry, and Pharmacology, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Gilbert C
authors.initials: GC
authors.lastname: White
authors.affiliation: James P. Wilmot Cancer Center and Department of Medicine, University of Rochester, Rochester, New York.
authors.forename: Charles W
authors.initials: CW
authors.lastname: Francis
authors.affiliation: Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio. Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Keith R
authors.initials: KR
authors.lastname: McCrae
authors.affiliation: Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Palumbo
authors.affiliation: Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
authors.forename: Gary E
authors.initials: GE
authors.lastname: Raskob
authors.affiliation: Clinical and Translational Epidemiology Unit and Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Chan
authors.affiliation: Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Anil K
authors.initials: AK
authors.lastname: Sood
mesh_terms: D035843:Biomedical Research / Q000379:methods*; D006801:Humans; D054547:National Cancer Institute (U.S.); D054555:National Heart, Lung, and Blood Institute (U.S.); D009369:Neoplasms / Q000150:complications*; D058028:Research Report; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D014481:United States