title: [CAUSES OF CHRONIC TUBERCULOSIS OF INTRATHORACIC LYMPH NODES IN CHILDREN, THE SPECIFIC FEATURES OF CLINICAL MANIFESTATIONS AND THERAPY].
abstract: Studying the results of examination in 59 children with tuberculosis of intrathoracic lymph nodes over time could establish the main causes of the chronic course of the disease, reveal the specific features of clinical manifestations, and define the optimal regimens of specific therapy. The chronic primary tuberculosis is characterized by a multiple intrathoracic lymph node lesion that corresponds to different phases of specific inflammation and is accompanied by complications in a third of cases. The signs of process activity are observed in 79.7%. Complex therapy lasted more than 10 months in 32.3% of cases and achieved recovery with insignificant residual changes in 69.5% of children. The basic causes of chronic tuberculosis are untimely and inadequate prophylactic measures in risk groups and failures in early tuberculosis detection in children.
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D057210:Delayed Diagnosis / Q000009:adverse effects / Q000517:prevention & control / Q000706:statistics & numerical data; D003951:Diagnostic Errors / Q000517:prevention & control / Q000706:statistics & numerical data; D004359:Drug Therapy, Combination / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D010043:Outcome and Process Assessment, Health Care; D062072:Patient Acuity; D012426:Russia / Q000453:epidemiology; D013909:Thorax; D061665:Time-to-Treatment; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents