title: Experiences and Perspectives of Polycystic Kidney Disease Patients following a Diet of Reduced Osmoles, Protein, and Acid Precursors Supplemented with Water: A Qualitative Study.
abstract: BACKGROUND
  Salt, protein, acid precursors, and fluid intake have been identified as factors that influence cyst growth in ADPKD. Unfortunately, the feasibility of following these dietary restrictions/enhancements from a patient's point-of-view has yet to be studied. The purpose of this study is to understand better the experiences of patients following a relatively complex dietary prescription targeting these factors.
  
  
  METHODS
  Twelve adults with ADPKD and kidney function >30ml/min/1.73m2 were recruited from the University of Kansas Medical Center Polycystic Kidney Disease clinic. In a qualitative design, semi-structured interviews of participants were conducted following a four week dietary intervention (experimental diet lower in sodium, protein, and acid precursors, and supplemented with water) either face-to-face or by telephone. All interviews were recorded, transcribed verbatim, and checked for accuracy. Transcripts were analyzed thematically for emerging themes.
  
  
  RESULTS
  Participants reported that eating less meat and more fruits and vegetables were the easiest components of the diet, whereas reaching the daily goal amount of fruits and vegetables and tracking the diet constantly were the most difficult components. Participants had little difficulty with fluid intake and reported the prescribed fluid goal as achievable. The tracking system for fruits and vegetables and protein was reported to be both helpful and intuitive, but tracking their intake on paper was tedious. Eating out was the most significant barrier to following the diet with some individuals avoiding restaurants in order to comply with the dietary prescription.
  
  
  CONCLUSIONS
  Participants on the experimental diet heightened their awareness of the consumption of dietary salt, protein, acid precursors, and fluid intake. Additionally, most participants believed adherence to the prescribed diet was feasible. However, participants wanted less cumbersome ways to track and monitor the diet, especially given that the prescribed diet is designed for lifelong adherence. Future studies should focus on targeting these specific dietary factors in larger groups of more ethnically and culturally diverse populations to help inform clinicians and how best to help diverse populations adhere to the dietary intervention.
  
  
  BACKGROUND
  ClinicalTrials.gov NCT01810614.
authors.affiliation: Department of Dietetics & Nutrition, School of Health Professions, University of Kansas Medical Center, Kansas City, KS, United States of America.|Department of Nutrition Services, Children's Mercy Hospital & Clinics, Kansas City, MO, United States of America.
authors.forename: Jacob M
authors.initials: JM
authors.lastname: Taylor
authors.affiliation: Division of Cardiovascular Diseases, School of Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.
authors.forename: Lauren
authors.initials: L
authors.lastname: Ptomey
authors.affiliation: Department of Dietetics & Nutrition, School of Health Professions, University of Kansas Medical Center, Kansas City, KS, United States of America.
authors.forename: Jill M
authors.initials: JM
authors.lastname: Hamilton-Reeves
authors.affiliation: Department of Dietetics & Nutrition, School of Health Professions, University of Kansas Medical Center, Kansas City, KS, United States of America.
authors.forename: Debra K
authors.initials: DK
authors.lastname: Sullivan
authors.affiliation: Department of Medicine-Nephrology, Kidney Institute, School of Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.
authors.forename: Catherine
authors.initials: C
authors.lastname: Creed
authors.affiliation: Department of Dietetics & Nutrition, School of Health Professions, University of Kansas Medical Center, Kansas City, KS, United States of America.
authors.forename: Susan E
authors.initials: SE
authors.lastname: Carlson
authors.affiliation: Department of Internal Medicine, Baylor Scott and White Health, Texas A&M Health Science Center College of Medicine, Temple, TX, United States of America.
authors.forename: Donald E
authors.initials: DE
authors.lastname: Wesson
authors.affiliation: Department of Medicine-Nephrology, Kidney Institute, School of Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.
authors.forename: Jared J
authors.initials: JJ
authors.lastname: Grantham
authors.affiliation: Department of Internal Medicine, Division of General Medicine, School of Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.
authors.forename: Cheryl A
authors.initials: CA
authors.lastname: Gibson
mesh_terms: D000328:Adult; D000368:Aged; D000596:Amino Acids / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D005638:Fruit; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008460:Meat; D008875:Middle Aged; D010349:Patient Compliance; D007690:Polycystic Kidney Diseases / Q000178:diet therapy* / Q000523:psychology; D036301:Qualitative Research; D012982:Sodium, Dietary / Q000008:administration & dosage*; D014675:Vegetables; D014867:Water / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D000596:Amino Acids; D004044:Dietary Proteins; D012982:Sodium, Dietary; D014867:Water