title: Rhodium(III)-Catalyzed C-H Activation: An Oxidative Intramolecular Heck-Type Reaction Directed by a Carboxylic Acid.
abstract: Carboxylic acids effectively direct C-H activation for Rhodium(III)-catalyzed intramolecular Heck-type reactions. A catalytic amount of Cu(OAc)2is used as the external oxidant with oxygen likely acting as the terminal oxidant. Additionally, a novel electron-deficient RhIIIcatalyst was found to be more effective that [RhCp*Cl2]2with some substrates. A wide variety of complex dihydrobenzofurans, dihydrobenzopyrans, and other bicycles that can be easily further functionalized are now accessible through relatively mild reaction conditions.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA).
authors.forename: Tyler A
authors.initials: TA
authors.lastname: Davis
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA).
authors.forename: Chuanqi
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO 80523 (USA).
authors.forename: Tomislav
authors.initials: T
authors.lastname: Rovis
keywords: C-H activation; Heck reaction; Rhodium (III) catalysis; cyclization; dihydrobenzofurans