title: [HER2 testing in gastric cancer - results of a German expert meeting].
abstract: Valid HER2 testing is essential for optimal therapy of patients with HER2 positive gastric cancer and the correct use of first-line treatment. While each breast cancer is routinely being tested for the HER2 status, HER2 testing in gastric cancer has still not become part of the routine and is often only done upon request by the therapist. An interdisciplinary German expert group took the challenges of HER2 testing in gastric cancer as an opportunity to address essential aspects and questions for the practical use of HER2 testing in this indication from the perspective of pathologists and therapists. The recommendations made in this manuscript reflect the consensus of all participants and correspond to their opinions and long-term experience.
authors.affiliation: Universitätsklinikum Leipzig, Universitäres Krebszentrum (UCCL), Leipzig, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Lordick
authors.affiliation: Krankenhaus Nordwest, Frankfurt am Main, Germany.
authors.forename: S E
authors.initials: SE
authors.lastname: Al-Batran
authors.affiliation: Universitätsmedizin Mannheim, Mannheim, Germany.
authors.forename: R D
authors.initials: RD
authors.lastname: Hofheinz
authors.affiliation: III. Medizinischen Klinik des Klinikums rechts der Isar, München, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Lorenzen
authors.affiliation: Charité - Universitätsmedizin Berlin, CVK: Campus Virchow-Klinikum Charité Centrum Tumormedizin CC14, Berlin, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Thuss-Patience
authors.affiliation: Institut für Pathologie, Universitätsklinikum Carl Gustav Carus, TU Dresden, Dresden, Germany.
authors.forename: G B
authors.initials: GB
authors.lastname: Baretton
authors.affiliation: Institut für Pathologie, Charité Universitätsmedizin Berlin Campus Mitte, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Dietel
authors.affiliation: Pathologisches Institut Mannheim, Mannheim, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Gaiser
authors.affiliation: Pathologisches Institut der Ludwig-Maximilians-Universität München, München, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Kirchner
authors.affiliation: Institut für Pathologie, Medizinische Hochschule Hannover, Hannover, Germany.
authors.forename: H H
authors.initials: HH
authors.lastname: Kreipe
authors.affiliation: Uniklinik Köln, Institut für Pathologie, Köln, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Quaas
authors.affiliation: Institut für Pathologie, Christian-Albrechts-Universität, Kiel, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Röcken
authors.affiliation: Institut für Pathologie Nordhessen u. Targos GmbH, Kassel, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Rüschoff
authors.affiliation: Georgius Agricola Stiftung Ruhr, Institut für Pathologie der Ruhr-Universität Bochum am Berufsgenossenschaftlichen Universitätsklinikum, Bergmannsheil, Bochum, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Tannapfel
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D003938:Diagnostic Techniques, Digestive System / Q000592:standards*; D019317:Evidence-Based Medicine; D005858:Germany; D008495:Medical Oncology / Q000592:standards*; D017410:Practice Guidelines as Topic; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human