title: New approach in the treatment of refractory vitiligo: CO2laser combined with betamethasone and salicylic acid solution.
abstract: The aim of this study is to evaluate the use of fractional carbon dioxide laser (CO2) with betamethasone and salicylic acid solution in the treatment of patients with refractory vitiligo in hands. Each hand of the patient was randomly assigned to one of two groups: lesion treated with fractional carbon dioxide laser associated with betamethasone and salicylic acid solution administration or lesion treated only with betamethasone and salicylic acid solution. We conclude that combined treatment with fractional carbon dioxide laser and betamethasone associated with salicylic acid solution could effectively and safely be used in the treatment of refractory vitiligo.
authors.affiliation: Dermatology Department, Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Paulo Rowilson
authors.initials: PR
authors.lastname: Cunha
authors.affiliation: Dermatology Department, Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Nabila
authors.initials: N
authors.lastname: Scabine Pessotti
authors.affiliation: Dermatology Department, Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Camila
authors.initials: C
authors.lastname: Bonati Mattos
authors.affiliation: Dermatology Department, Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Ana Flavia
authors.initials: AF
authors.lastname: Salai
mesh_terms: D000328:Adult; D001623:Betamethasone / Q000627:therapeutic use*; D001938:Brazil; D003131:Combined Modality Therapy; D004338:Drug Combinations; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D054020:Lasers, Gas / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000295:instrumentation*; D008875:Middle Aged; D019999:Pharmaceutical Solutions; D020156:Salicylic Acid / Q000627:therapeutic use*; D012880:Skin Pigmentation / Q000187:drug effects* / Q000528:radiation effects*; D016896:Treatment Outcome; D014820:Vitiligo / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D055815:Young Adult
chemical_list: D004338:Drug Combinations; D005938:Glucocorticoids; D019999:Pharmaceutical Solutions; D001623:Betamethasone; D020156:Salicylic Acid
keywords: CO2 laser; salicilic acid; vitiligo