title: [Analysis of Clinical Prognosis of 50 Cases of Primary Gastrointestinal Non-Hodgkin's Lymphoma].
abstract: OBJECTIVE
  To analyze the clinical pathologic characteristics, diagnosis, treatment and outcome of patients with primary gastrointestinal non-Hodgkin's lymphoma(PGI-NHL).
  
  
  METHODS
  The clinical and pathological features of 50 cases of PGI-NHL were analyzed retrospectively, the Kaplan-Meier was applied to estimate the survival time of all the patients.
  
  
  RESULTS
  The median age of patients was 58 years old, the cases of male patient were more than that of femal. The main clinical symptoms included pain and discomfort. The patients of Ⅰ-Ⅱstage accounted for 66%, DLBCL was most common. The clinical and pathological features were not significantly different between gastric and intestinal lymphoma. In 58% of the patients, surgery was the first choice for treatment. The median survival time was 74 months. The OS rates at 1-, 3- and 5-year were 78%, 65.9% and 61.8% respectively. Log-rank univariate analysis showed that age, sex, ECOG score, B symptoms, disease location and treatment methods all did not relate with OS, however, IPI, stage, LDH, cell phenotype and pathological type closely related with the OS.
  
  
  CONCLUSIONS
  As lacking characteristic clinical manifestations of PGI-NHL, the DLBCL is the most common type. The prognosis of B cell lymphoma is significantly better than that of T cell lymphoma. The prognosis of PTCL is the worst.
authors.affiliation: Department of Internal Medicine, Liaoning Cancer Hospital & Institute, Chinese Medical University, Shenyang 110042, Liaoning Province, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Department of Internal Medicine, Liaoning Cancer Hospital & Institute, Chinese Medical University, Shenyang 110042, Liaoning Province, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Gao
authors.affiliation: Department of Internal Medicine, Liaoning Cancer Hospital & Institute, Chinese Medical University, Shenyang 110042, Liaoning Province, China.
authors.forename: Cheng-Yu
authors.initials: CY
authors.lastname: Hong
authors.affiliation: Department of Radiology, Liaoning Cancer Hospital & Institute, Chinese Medical University, Shenyang 110042, Liaoning Province, China.
authors.forename: Xiao-Ru
authors.initials: XR
authors.lastname: Bai
authors.affiliation: Department of Information, Liaoning Cancer Hospital & Institute, Chinese Medical University, Shenyang 110042, Liaoning Province, China.
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Lin
authors.affiliation: Department of Internal Medicine, Liaoning Cancer Hospital & Institute, Chinese Medical University, Shenyang 110042, Liaoning Province, China.E-mail: xiaolingli001@163.com.
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Li
mesh_terms: D005260:Female; D005770:Gastrointestinal Neoplasms; D006801:Humans; D008228:Lymphoma, Non-Hodgkin; D016399:Lymphoma, T-Cell; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies