title: Lymphoid Neoplasia: Correlations Between Morphology and Flow Cytometry.
abstract: Cytology is commonly used to diagnose lymphoma and leukemia. Frequently, a diagnosis of lymphoproliferative disease can be obtained via cytology, and some of the common subtypes of canine lymphoma and leukemia can have characteristic cytologic features. Flow cytometry is a critical tool in the objective diagnosis and further characterization of lymphoma and leukemia. Features of the immunophenotype, such as expression of certain cell surface proteins or cell size, can provide important prognostic information. This review describes the cytologic features, flow cytometry immunophenotype, and immunophenotypic prognostic information for 6 major types of canine lymphoma and leukemia.
authors.affiliation: Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 314-4 Diagnostic Medicine Center, 200 West Lake Street, 1644 Campus Delivery, Fort Collins, CO 80523-1644, USA.
authors.forename: Emily D
authors.initials: ED
authors.lastname: Rout
authors.affiliation: Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 309 Diagnostic Medicine Center, 200 West Lake Street, 1644 Campus Delivery, Fort Collins, CO 80523-1644, USA. Electronic address: paul.avery@colostate.edu.
authors.forename: Paul R
authors.initials: PR
authors.lastname: Avery
mesh_terms: D000818:Animals; D003584:Cytological Techniques / Q000379:methods / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005434:Flow Cytometry / Q000379:methods / Q000662:veterinary*; D006801:Humans; D007938:Leukemia / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*
keywords: Canine; Cytology; Flow cytometry; Immunophenotype; Leukemia; Lymphoma