title: Blastomycosis of the nose: A case report.
abstract: Blastomyces dermatitidis is a thermally dimorphic fungus endemic to the North American soil near the Mississippi, Ohio, and St. Lawrence river valleys, as well as the Great Lakes Basin. It is responsible for blastomycosis, a systemic pyogranulomatous disease. Blastomycosis of the head and neck is decidedly uncommon and often mistaken for cancer. There are only 3 previous case reports of blastomycosis presenting as an intranasal lesion. We report the unusual case of a 24-year-old man with blastomycosis presenting with a 4-week history of a progressively enlarging intranasal mass who had complete resolution of symptoms after treatment with itraconazole and surgical excision of the lesion.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Gatch Hall, 1120 W. Michigan St., Suite 200, Indianapolis, IN 46202, USA. thomas.jetmore@gmail.com.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Jetmore
authors.forename: Jennifer
authors.initials: J
authors.lastname: Phan
authors.forename: Abideen O
authors.initials: AO
authors.lastname: Yekinni
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001758:Blastomyces; D001759:Blastomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003937:Diagnosis, Differential; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D009666:Nose / Q000382:microbiology; D009668:Nose Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D009669:Nose Neoplasms / Q000175:diagnosis; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole