title: Subsidence of total ankle component associated with deterioration of an ankle scale in non-inflammatory arthritis but not in rheumatoid arthritis.
abstract: OBJECTIVE
  Modern three-component total ankle arthroplasty (TAA) has favorable clinical results and survival rates. However, radiographic deterioration and worsening of clinical symptoms may occur in patients with rheumatoid arthritis (RA) or non-inflammatory arthritis (NA). The associations between outcomes and clinical and radiological factors are not clear. We compared midterm clinical and radiographic outcomes after TAA between patients with RA and those with NA.
  
  
  METHODS
  Twenty-six TAAs were performed using a three-component prosthesis, the FINE Total Ankle System during the study period. Fourteen TAAs with 11 RA patients undergoing primary TAA were compared with twelve TAAs with 12 NA patients. Clinical and radiographic outcomes were evaluated before and after operation, and at the final follow-up.
  
  
  RESULTS
  The Japanese Society for Surgery of the Foot (JSSF) scale improved significantly following TAA in both groups (p = 0.0039 and 0.0156, respectively). Tibial subsidence, talar subsidence and age were significantly associated with postoperative JSSF score only in the NA group (p = 0.0027, 0.0017 and p < 0.0001, respectively). Stepwise regression analysis showed that talar subsidence was an independent predictor of a worse JSSF score in the NA group (F = 10.3).
  
  
  CONCLUSIONS
  The final clinical outcome was negatively influenced by talar subsidence in patients with NA, but not in those with RA.
authors.affiliation: a Department of Orthopaedic Surgery , Graduate School of Medicine, Kyoto University , Kyoto , Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Iwata
authors.affiliation: a Department of Orthopaedic Surgery , Graduate School of Medicine, Kyoto University , Kyoto , Japan.
authors.forename: Hiromu
authors.initials: H
authors.lastname: Ito
authors.affiliation: a Department of Orthopaedic Surgery , Graduate School of Medicine, Kyoto University , Kyoto , Japan.|b Department of the Control for Rheumatic Diseases , Graduate School of Medicine, Kyoto University , Kyoto , Japan.
authors.forename: Moritoshi
authors.initials: M
authors.lastname: Furu
authors.affiliation: a Department of Orthopaedic Surgery , Graduate School of Medicine, Kyoto University , Kyoto , Japan.|b Department of the Control for Rheumatic Diseases , Graduate School of Medicine, Kyoto University , Kyoto , Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ishikawa
authors.affiliation: a Department of Orthopaedic Surgery , Graduate School of Medicine, Kyoto University , Kyoto , Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Azukizawa
authors.affiliation: c Department of Tissue Regeneration , The Institute for Frontier Medical Sciences, Graduate School of Medicine, Kyoto University , Kyoto , Japan , and.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yoshitomi
authors.affiliation: a Department of Orthopaedic Surgery , Graduate School of Medicine, Kyoto University , Kyoto , Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Fujii
authors.affiliation: d Department of Orthopaedic Surgery , Graduate School of Medicine, Gifu University , Gifu , Japan.
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Akiyama
authors.affiliation: a Department of Orthopaedic Surgery , Graduate School of Medicine, Kyoto University , Kyoto , Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Matsuda
mesh_terms: D000328:Adult; D000368:Aged; D000843:Ankle Joint / Q000000981:diagnostic imaging / Q000601:surgery; D001172:Arthritis, Rheumatoid / Q000601:surgery*; D058737:Arthroplasty, Replacement, Ankle / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D011859:Radiography; D012086:Reoperation / Q000706:statistics & numerical data; D016896:Treatment Outcome
keywords: Clinical outcome; Non-inflammatory arthritis; Radiological outcome; Rheumatoid arthritis; Total ankle arthroplasty