title: Fibromuscular Dysplasia Complicated With Cerebral Stroke in a Child With Congenital Dyserythropoietic Anemia Type II.
abstract: Congenital dyserythropoietic anemia type II belongs to a subtype of bone marrow failure syndrome, which is characterized by monolineage involvement and typical morphologic abnormalities in erythroid precursor cells resulting in different degrees of hyporegenerative anemia. Moreover, reticulocytosis, which is not corresponding to the degree of anemia, with jaundice and splenomegaly are major diagnostic criteria. Causative gene is located at SEC23B. Although stroke among children is rare, it can cause significant morbidity and mortality. Herein we present a 3-year-old male with congenital dyserythropoietic anemia type II who presented with stroke-like symptoms, and was diagnosed with fibromuscular dysplasia.
authors.affiliation: Departments of *Pediatrics, Division of Pediatric Hematology Oncology †Pediatrics, Division of Pediatric Neurology ‡Radiology, Division of Interventional Radiology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Ozcan
authors.forename: Turkan
authors.initials: T
authors.lastname: Patiroglu
authors.forename: Hamit
authors.initials: H
authors.lastname: Acer
authors.forename: Hakan
authors.initials: H
authors.lastname: Gumus
authors.forename: Serkan
authors.initials: S
authors.lastname: Senol
authors.forename: Musa
authors.initials: M
authors.lastname: Karakukcu
authors.forename: Mehmet A
authors.initials: MA
authors.lastname: Ozdemir
authors.forename: Ekrem
authors.initials: E
authors.lastname: Unal
mesh_terms: D000742:Anemia, Dyserythropoietic, Congenital / Q000150:complications*; D002675:Child, Preschool; D005352:Fibromuscular Dysplasia / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007565:Jaundice; D008297:Male; D045262:Reticulocytosis; D013163:Splenomegaly; D020521:Stroke / Q000209:etiology*