title: Effect of Metabolic Syndrome on the Outcome of Corticosteroid Injection for Trigger Finger: Matched Case-Control Study.
abstract: OBJECTIVE
  To compare the efficacy of corticosteroid injections in treating trigger finger in patients with and without metabolic syndrome (MS).
  
  
  METHODS
  Fifty-one patients with trigger finger and MS were matched for age and sex with 52 control patients without MS. All patients were treated with a single corticosteroid injection. The response to treatment, including objective triggering, tenderness at the A1 pulley, and Quick Disabilities of the Arm, Shoulder, and Hand score (QuickDASH) were assessed at 6, 12, and 24 weeks' follow-up. Before the 24-week evaluation, 7 in the MS group and 10 in the control group were lost to follow-up.
  
  
  RESULTS
  Prior to treatment, patients with MS had Quinnell grades and initial mean QuickDASH scores similar to those in the control group. The proportion of treatment failure for the MS group (49%) was significantly higher than that of control group (19%) after 6 months' follow-up. Unresolved triggering was more prevalent in patients in the MS group at the 12- and 24-week follow-ups. Local tenderness was more persistent in the MS group than in the control group throughout the 24 weeks of follow-up. After 24 weeks of follow-up, 14 patients (27%) in the MS group and 6 (12%) in the control group underwent surgical release. QuickDASH scores of the MS group were worse than those of the control group at the 12- and 24-week follow-ups.
  
  
  CONCLUSIONS
  Trigger finger patients with MS are at risk of poorer functional outcomes and treatment failure after a single corticosteroid injection than age- and sex-matched controls.
  
  
  METHODS
  Therapeutic III.
authors.affiliation: Department of Orthopaedic Surgery, Ewha Womans University School of Medicine, Ewha Womans University Medical Center, Seoul, Korea.
authors.forename: Young Hak
authors.initials: YH
authors.lastname: Roh
authors.affiliation: Department of Orthopaedic Surgery, Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
authors.forename: Beom Koo
authors.initials: BK
authors.lastname: Lee
authors.affiliation: Department of Orthopaedic Surgery, Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
authors.forename: Jong Keun
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Orthopaedic Surgery, Kangwon National University Hospital, Chuncheon-si, Gangwon-do, Korea. Electronic address: bestknee@hotmail.com.
authors.forename: Jung Ho
authors.initials: JH
authors.lastname: Noh
authors.affiliation: Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Hyun Sik
authors.initials: HS
authors.lastname: Gong
authors.affiliation: Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Goo Hyun
authors.initials: GH
authors.lastname: Baek
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D010147:Pain Measurement / Q000187:drug effects; D016059:Range of Motion, Articular / Q000187:drug effects / Q000502:physiology*; D012016:Reference Values; D012189:Retrospective Studies; D012720:Severity of Illness Index; D017211:Treatment Failure; D052582:Trigger Finger Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*
chemical_list: D000305:Adrenal Cortex Hormones
keywords: Trigger finger; corticosteroid injection; metabolic syndrome