title: [EFFECT OF THE POLYENZYME DRUG WOBENZYM ON THE ACTIVITY OF A DESTRUCTIVE INFLAMMATORY PROCESS IN THE COMPLEX THERAPY OF PULMONARY TUBERCULOSIS].
abstract: Ninety patients with new-onset pulmonary tuberculosis were examined prior to therapy The patients were randomized into 2 groups: 1) 20 patients receiving the standard antibiotic therapy regimen; 2) 70 patients taking the standard antibiotic therapy and the polyenzyme drug Wobenzym. The use of the latter in the complex therapy of patients with pulmonary tuberculosis was shown to cause an increase in the activity of the destructive inflammatory process and to regulate the function of the immune system as compared with those during the standard therapy.
authors.forename: A V
authors.initials: AV
authors.lastname: Yakimova
authors.forename: A P
authors.initials: AP
authors.lastname: Ievlev-Duntau
authors.forename: K A
authors.initials: KA
authors.lastname: Lipsky
authors.forename: A N
authors.initials: AN
authors.lastname: Trunov
authors.forename: V A
authors.initials: VA
authors.lastname: Shkurupiy
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000009:adverse effects; D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000009:adverse effects; D004338:Drug Combinations; D016903:Drug Monitoring / Q000379:methods; D004359:Drug Therapy, Combination / Q000379:methods; D005260:Female; D006801:Humans; D006867:Hydrolases / Q000008:administration & dosage / Q000009:adverse effects; D053583:Interleukin-1beta / Q000097:blood; D008297:Male; D015166:Monitoring, Immunologic / Q000379:methods; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000276:immunology; D012431:Rutin / Q000008:administration & dosage / Q000009:adverse effects; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D000995:Antitubercular Agents; D004338:Drug Combinations; D053583:Interleukin-1beta; D012431:Rutin; C023295:Wobenzym; D006867:Hydrolases