title: A simple and rapid test of physical performance inchronic obstructive pulmonary disease.
abstract: Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal study of comorbidities in COPD, submaximal physical performance was determined in 520 patients and 150 controls using the TUG test and 6MWD. Spirometry, body composition, handgrip strength, the COPD assessment test, St George's Respiratory Questionnaire (SGRQ), and the modified Medical Research Council dyspnoea scale were also determined. Patients and controls were similar in age, body mass index, and sex proportions. The TUG in the patients was greater than that in the control group, P=0.001, and was inversely related to 6MWD (r=-0.71, P<0.001) and forced expiratory volume in one second predicted (r=-0.19, P<0.01) and was directly related to the SGRQ activity (r=0.39, P<0.001), SGRQ total (r=0.37, P<0.001), and total COPD assessment test scores (r=0.37, P<0.001). The TUG identified the difference in physical performance between patients and controls. The TUG test and validated questionnaires provide a measure of physical performance, which is rapid and could be used in clinical practice.
authors.affiliation: Physiotherapy Department, School of Healthcare Sciences, University Hospital of Wales, Cardiff University, Cardiff, UK.
authors.forename: Ali Mufraih
authors.initials: AM
authors.lastname: Albarrati
authors.affiliation: Physiotherapy Department, School of Healthcare Sciences, University Hospital of Wales, Cardiff University, Cardiff, UK.
authors.forename: Nichola S
authors.initials: NS
authors.lastname: Gale
authors.affiliation: Physiotherapy Department, School of Healthcare Sciences, University Hospital of Wales, Cardiff University, Cardiff, UK.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Enright
authors.affiliation: Cardiorespiratory Medicine Department, Cardio-Respiratory Medicine, Wales Heart Research Institute, Cardiff University, University Hospital of Wales, Cardiff, UK.
authors.forename: Margaret M
authors.initials: MM
authors.lastname: Munnery
authors.affiliation: Cardiorespiratory Medicine Department, Cardio-Respiratory Medicine, Wales Heart Research Institute, Cardiff University, University Hospital of Wales, Cardiff, UK.
authors.forename: John R
authors.initials: JR
authors.lastname: Cockcroft
authors.affiliation: Cardiorespiratory Medicine Department, Cardio-Respiratory Medicine, Wales Heart Research Institute, Cardiff University, University Hospital of Wales, Cardiff, UK.
authors.forename: Dennis J
authors.initials: DJ
authors.lastname: Shale
mesh_terms: D000367:Age Factors; D000368:Aged; D019540:Area Under Curve; D001823:Body Composition; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D004417:Dyspnea / Q000209:etiology / Q000503:physiopathology; D017079:Exercise Tolerance; D005260:Female; D015577:Geriatric Assessment / Q000379:methods*; D018737:Hand Strength; D006801:Humans; D008137:Longitudinal Studies; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D012372:ROC Curve; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013147:Spirometry; D011795:Surveys and Questionnaires; D013997:Time Factors; D000070857:Walk Test
keywords: COPD; physical inactivity; timed up and go test