title: Irreversible electroporation in locally advanced pancreatic cancer: A call for standardization of energy delivery.
abstract: Irreversible Electroporation (IRE) is used to treat locally advanced cancers, commonly of the pancreas, liver, kidney, and other soft tissues. Precise eligibility for IRE should be established in each individual patient by a multidisciplinary team based on comprehensive clinical, imaging, and laboratory assessment. Standardization of IRE technique and protocols is expected to improve safety, lead to reproducible outcomes, and facilitate further research into IRE. The present article provides a set of technical recommendations for the use of IRE in the treatment of locally advanced pancreatic cancer. J. Surg. Oncol. 2016;114:865-871. © 2016 2016 Wiley Periodicals, Inc.
authors.affiliation: Division of Surgical Oncology, Hiram C Polk Jr Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky. robert.martin@louisville.edu.
authors.forename: Robert C G
authors.initials: RC
authors.lastname: Martin
authors.affiliation: Division of Surgical Oncology, Hiram C Polk Jr Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky.
authors.forename: Alan North
authors.initials: AN
authors.lastname: Durham
authors.affiliation: Department of Surgery, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.
authors.forename: Marc G
authors.initials: MG
authors.lastname: Besselink
authors.affiliation: Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: David
authors.initials: D
authors.lastname: Iannitti
authors.affiliation: Johns Hopkins University Hospital, Baltimore, Maryland.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Weiss
authors.affiliation: Department of Surgery and Hepatitis Research Center, National Taiwan University Hospital, China and Singapore Universities Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Wolfgang
authors.affiliation: Department of Surgery and Hepatitis Research Center, National Taiwan University Hospital, China and Singapore Universities Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Kai-Wen
authors.initials: KW
authors.lastname: Huang
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy*; D000359:Aftercare; D018274:Electroporation / Q000379:methods* / Q000592:standards; D006801:Humans; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000628:therapy*; D018579:Patient Selection
keywords: irreversible electroporation; pancreatic cancer; technique