title: [Management of arterial hypertension before 20weeks gestation in pregnant women].
abstract: In the first 6 months of pregnancy, the primary goal of antihypertensive treatment is to prevent the complications of severe hypertension. Initiation of antihypertensive drug treatment is recommended in pregnant women with severe hypertension (blood pressure>160/110mmHg). Initiation of antihypertensive drug treatment should also be considered in pregnant women at high cardiovascular risk (diabetes, chronic kidney disease, personal history of cardiovascular disease) with moderate hypertension (blood pressure between 140-159/90-109mmHg). A systolic blood pressure goal<160 and a diastolic blood pressure goal between 85 and 100mmHg is recommended in pregnancy. Labetalol, nifedipine, nicardipine and alphamethyldopa should be considered preferential antihypertensive drugs in pregnancy. Salt restriction, physical exercise and weight loss have not demonstrated any effect in the prevention of preeclampsia and serious maternal complications of hypertension.
authors.affiliation: CHU de Toulouse, université Paul-Sabatier, service d'hypertension artérielle et de thérapeutique, 31059 Toulouse, France.
authors.forename: Florent
authors.initials: F
authors.lastname: Seguro
authors.affiliation: CHU de Toulouse, université Paul-Sabatier, service d'hypertension artérielle et de thérapeutique, 31059 Toulouse, France.
authors.forename: Béatrice
authors.initials: B
authors.lastname: Duly Bouhanick
authors.affiliation: CHU de Toulouse, université Paul-Sabatier, service d'hypertension artérielle et de thérapeutique, 31059 Toulouse, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Chamontin
authors.affiliation: CHU de Toulouse, université Paul-Sabatier, service d'hypertension artérielle et de thérapeutique, 31059 Toulouse, France. Electronic address: amar.j@chu-toulouse.fr.
authors.forename: Jacques
authors.initials: J
authors.lastname: Amar
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D003663:Decision Trees; D005260:Female; D006801:Humans; D006973:Hypertension / Q000628:therapy; D046110:Hypertension, Pregnancy-Induced / Q000628:therapy*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000628:therapy; D011262:Pregnancy Trimester, Second
chemical_list: D000959:Antihypertensive Agents