title: Resolution of inverse psoriasis after treatment with levodopa for Parkinson's disease.
abstract: Inverse psoriasis is characterized by the development of erythematous shiny plaques at intertriginous areas of the body. It has a prevalence of 2% worldwide. The usefulness of levodopa in psoriasis was discovered in 1970 but nowadays it is not a standard therapy for this condition. A 74-year-old woman was diagnosed with Parkinson's disease subsequent to the development of extensive inverse psoriasis. The skin lesions were resistant to classical topical and systemic medications. Treatment with levodopa was initiated in order to treat her neurological problem and progressive remission of the skin lesions was noted. We highlight the role of dopamine in the pathophysiology of this dermatosis.
authors.affiliation: Department of Neurology, Puerta del Mar University Hospital, Cádiz, Spain.
authors.forename: Natalia
authors.initials: N
authors.lastname: Rojo Suárez
authors.affiliation: Department of Dermatology, Puerta del Mar University Hospital, Cádiz, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Jiménez Gallo
authors.affiliation: Department of Dermatology, Puerta del Mar University Hospital, Cádiz, Spain.
authors.forename: Cintia
authors.initials: C
authors.lastname: Arjona Aguilera
authors.affiliation: Department of Neurology, Puerta del Mar University Hospital, Cádiz, Spain.
authors.forename: Raúl
authors.initials: R
authors.lastname: Espinosa Rosso
authors.affiliation: Department of Dermatology, Puerta del Mar University Hospital, Cádiz, Spain.
authors.forename: Mario
authors.initials: M
authors.lastname: Linares Barrios
mesh_terms: D000368:Aged; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D011565:Psoriasis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D012074:Remission Induction; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa
keywords: Parkinson's disease; intertriginous psoriasis; inverse psoriasis; levodopa