title: Levels and Profiles of Polybrominated Diphenyl Ethers in Breast Milk During Different Nursing Durations.
abstract: Eight PBDE congeners, BDE-28, 47, 99, 100, 153, 154, 183 and 209, were measured using gas chromatography coupled to mass spectrometry. The concentrations of Σ8PBDEs ranged from 0.04 to 19.93 ng g(-1) lipid weight (lw), with median and mean value of 1.21 and 2.72 ng g(-1) lw. PBDE congeners were detected in approximately 90 % of samples with BDE-209 as the dominant one. No significant correlations were found between the mothers' age, body mass index and PBDEs concentrations. We estimated the infant's dietary intake of the studied PBDEs via human milk during different nursing durations, and found that babies younger than 1 month might take a relatively higher body burden of PBDEs. The median levels of Σ8PBDEs were 0.74, 2.80, 2.43 and 0.90 ng g(-1) lw in colostrum, milk sampled at 1, 3 and 6 months after birth, respectively. High consumption of animal-origin food after birth may lead to the elevated ΣPBDEs concentrations in breast milk. A rational nutrition deployment is essential for postpartum mother.
authors.affiliation: State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing, 100871, People's Republic of China.
authors.forename: Lixin
authors.initials: L
authors.lastname: Yang
authors.affiliation: Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, 050021, People's Republic of China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, 050021, People's Republic of China.
authors.forename: Liying
authors.initials: L
authors.lastname: Wang
authors.affiliation: Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, 050021, People's Republic of China.
authors.forename: Fengqi
authors.initials: F
authors.lastname: Chang
authors.affiliation: State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing, 100871, People's Republic of China. jbzhang@pku.edu.cn.
authors.forename: Jianbo
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang, 050021, People's Republic of China. liuyinping0930@163.com.
authors.forename: Yinping
authors.initials: Y
authors.lastname: Liu
mesh_terms: D001942:Breast Feeding; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000032:analysis*; D006801:Humans; D008895:Milk, Human / Q000737:chemistry*; D013997:Time Factors
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers
keywords: Breast milk; Diet; GC/MS; Nursing duration; Polybrominated diphenyl ethers; Risk assessment