title: Sedentary Behavior and Cardiovascular Morbidity and Mortality: A Science Advisory From the American Heart Association.
abstract: Epidemiological evidence is accumulating that indicates greater time spent in sedentary behavior is associated with all-cause and cardiovascular morbidity and mortality in adults such that some countries have disseminated broad guidelines that recommend minimizing sedentary behaviors. Research examining the possible deleterious consequences of excess sedentary behavior is rapidly evolving, with the epidemiology-based literature ahead of potential biological mechanisms that might explain the observed associations. This American Heart Association science advisory reviews the current evidence on sedentary behavior in terms of assessment methods, population prevalence, determinants, associations with cardiovascular disease incidence and mortality, potential underlying mechanisms, and interventions. Recommendations for future research on this emerging cardiovascular health topic are included. Further evidence is required to better inform public health interventions and future quantitative guidelines on sedentary behavior and cardiovascular health outcomes.
authors.forename: Deborah Rohm
authors.initials: DR
authors.lastname: Young
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Hivert
authors.forename: Sofiya
authors.initials: S
authors.lastname: Alhassan
authors.forename: Sarah M
authors.initials: SM
authors.lastname: Camhi
authors.forename: Jane F
authors.initials: JF
authors.lastname: Ferguson
authors.forename: Peter T
authors.initials: PT
authors.lastname: Katzmarzyk
authors.forename: Cora E
authors.initials: CE
authors.lastname: Lewis
authors.forename: Neville
authors.initials: N
authors.lastname: Owen
authors.forename: Cynthia K
authors.initials: CK
authors.lastname: Perry
authors.forename: Juned
authors.initials: J
authors.lastname: Siddique
authors.forename: Celina M
authors.initials: CM
authors.lastname: Yong
mesh_terms: D000572:American Heart Association; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000401:mortality*; D006801:Humans; D009017:Morbidity / Q000639:trends*; D009043:Motor Activity / Q000502:physiology*; D015995:Prevalence; D012307:Risk Factors; D057185:Sedentary Behavior; D014481:United States
keywords: AHA Scientific Statements; adults; cardiovascular disease; diabetes mellitus; metabolic syndrome; mortality; prevalence; sedentary lifestyle