title: Feasibility and validity of mobile cognitive testing in the investigation of age-related cognitive decline.
abstract: Mobile cognitive testing may be used to help characterize subtle deficits at the earliest stages of cognitive decline. Despite growing interest in this approach, comprehensive information concerning its feasibility and validity has been lacking in elderly samples. Over a one-week period, this study applied mobile cognitive tests of semantic memory, episodic memory and executive functioning in a cohort of 114 elderly non-demented community residents. While the study acceptance rate was moderate (66%), the majority of recruited individuals met minimal compliance thresholds and responded to an average of 82% of the repeated daily assessments. Missing data did not increase over the course of the study, but practice effects were observed for several test scores. However, even when controlling for practice effects, traditional neuropsychological tests were significantly associated with mobile cognitive test scores. In particular, the Isaacs Set Test was associated with mobile assessments of semantic memory (γ = 0.084, t = 5.598, p < 0.001), the Grober and Buschke with mobile assessments of episodic memory (γ = 0.069, t = 3.156, p < 0.01, and the Weschler symbol coding with mobile assessments of executive functioning (γ = 0.168, t = 4.562, p < 0.001). Mobile cognitive testing in the elderly may provide complementary and potentially more sensitive data relative to traditional neuropsychological assessment. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: University of Bordeaux, Bordeaux, France.|CNRS, INCIA, UMR 5287, Bordeaux, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Schweitzer
authors.affiliation: Institut de Psychologie, Université Paris Descartes, Sorbonne Paris Cité, Institut Universitaire de France, Boulogne Billancourt, France.
authors.forename: Mathilde
authors.initials: M
authors.lastname: Husky
authors.affiliation: University of Bordeaux, Bordeaux, France.|CNRS, INCIA, UMR 5287, Bordeaux, France.|EPHE, Bordeaux, France.|CHU de Bordeaux, France.
authors.forename: Michèle
authors.initials: M
authors.lastname: Allard
authors.affiliation: University of Bordeaux, Bordeaux, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Amieva
authors.affiliation: University of Bordeaux, ISPED, Centre INSERM U897-Epidémiologie-Biostatistique, Bordeaux, France.|INSERM, ISPED, Centre INSERM U897-Epidémiologie-Biostatistique, Bordeaux, France.
authors.forename: Karine
authors.initials: K
authors.lastname: Pérès
authors.affiliation: University of Bordeaux, ISPED, Centre INSERM U897-Epidémiologie-Biostatistique, Bordeaux, France.|INSERM, ISPED, Centre INSERM U897-Epidémiologie-Biostatistique, Bordeaux, France.|University Hospital, Memory Consultation, CMRR, Bordeaux, France.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Foubert-Samier
authors.affiliation: University of Bordeaux, ISPED, Centre INSERM U897-Epidémiologie-Biostatistique, Bordeaux, France.|INSERM, ISPED, Centre INSERM U897-Epidémiologie-Biostatistique, Bordeaux, France.|University Hospital, Memory Consultation, CMRR, Bordeaux, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Dartigues
authors.affiliation: University of Bordeaux, Bordeaux, France.|CNRS, INCIA, UMR 5287, Bordeaux, France.|EPHE, Bordeaux, France.
authors.forename: Joel
authors.initials: J
authors.lastname: Swendsen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000066492:Cognitive Aging; D060825:Cognitive Dysfunction / Q000175:diagnosis*; D003936:Diagnosis, Computer-Assisted / Q000592:standards*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008491:Medical Informatics Applications; D063731:Mobile Applications; D015203:Reproducibility of Results
keywords: EMA; ESM; ecological momentary assessment; experience sampling method; mobile cognitive test; mobile neuropsychological test