title: Preparation and characterization of a novel Astragalus membranaceus polysaccharide-iron (III) complex.
abstract: Astragalus membranaceus polysaccharide-iron (III) complex (APS-iron) was synthesized and characterized. Based on single factor and response surface optimization experiments of APS-iron (III) complex synthesis, the optimum conditions of APS-iron (III) complex were obtained as follows: the reaction temperature 89.46°C, pH 8.16, reaction time 46.04min and ratio of catalyst to APS 0.75, respectively. The reaction temperature was the most significant factor, followed by pH, reaction time and the ratio of catalyst to APS in the four reaction parameters. The highest iron content (19.32%) of APS-iron (III) complex was obtained at the optimum conditions, which was characterized by fourier transform infrared (FTIR), scanning electron microscopy (SEM), antioxidant activities of the APS-iron (III) complex and iron release of APS-iron (III) complex in vitro assay. The results indicated the APS-iron (III) complex had good bioavailability and antioxidant activities in vitro assays. So, it was potential for APS-iron (III) complex as a candidate for iron supplements.
authors.affiliation: Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Lu
authors.affiliation: Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Xu
authors.affiliation: Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.
authors.forename: Yongbin
authors.initials: Y
authors.lastname: Meng
authors.affiliation: Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.affiliation: Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China. Electronic address: zuyuangangnefu@126.com.
authors.forename: Yuangang
authors.initials: Y
authors.lastname: Zu
authors.affiliation: Heilongjiang Vocational Institute Ecological Engineering, Harbin 150025, China. Electronic address: zmh_lq@126.com.
authors.forename: Minghua
authors.initials: M
authors.lastname: Zhu
mesh_terms: D027885:Astragalus propinquus / Q000737:chemistry*; D032701:Biomimetics; D001826:Body Fluids / Q000378:metabolism; D016166:Free Radical Scavengers / Q000737:chemistry*; D007501:Iron / Q000737:chemistry* / Q000378:metabolism; D009942:Organometallic Compounds / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry*
chemical_list: D016166:Free Radical Scavengers; D009942:Organometallic Compounds; D011134:Polysaccharides; D007501:Iron
keywords: Antioxidant activity; Astragalus membranaceus polysaccharide-iron (III) complex; Iron release