title: Membrane-disrupting iridium(iii) oligocationic organometallopeptides.
abstract: A series of oligoarginine peptide derivatives containing cyclometallated iridium(iii) units display remarkable cytotoxicity, comparable to that of cisplatin. In vitro studies with unilamellar vesicles support a membrane-disrupting mechanism of action.
authors.affiliation: Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS) and Departamento de Química Inorgánica, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain. miguel.vazquez.lopez@usc.es.
authors.forename: Iria
authors.initials: I
authors.lastname: Salvadó
authors.forename: Ilaria
authors.initials: I
authors.lastname: Gamba
authors.forename: Javier
authors.initials: J
authors.lastname: Montenegro
authors.forename: José
authors.initials: J
authors.lastname: Martínez-Costas
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: Brea
authors.forename: María Isabel
authors.initials: MI
authors.lastname: Loza
authors.forename: Miguel
authors.initials: M
authors.lastname: Vázquez López
authors.forename: M Eugenio
authors.initials: ME
authors.lastname: Vázquez