title: Heritability of Children's Dietary Intakes: A Population-Based Twin Study in China.
abstract: Despite evidence for some genetic control of dietary intake in adults, there is little evidence of how genetic factors influence children's dietary patterns.
  
  
  
  To estimate heritability of dietary intake in twin children from China and test if genetic effects on dietary intakes vary by the children's socio-economic status (SES).
  
  
  
  A sample of 622 twins (162 monozygotic and 149 dizygotic pairs; 298 boys and 324 girls aged 7-15 years) was recruited in South China. Dietary intakes were assessed using a validated 145-item semi-quantitative food frequency questionnaire. Pooled and sex-specific dietary patterns were identified using factor analysis. Heritability was estimated using structural equation models.
  
  
  
  Heritable components differed by gender and for nutrients and food groups; and estimated heritability of dietary patterns was generally greater in girls than boys. In boys, estimated heritabilities ranged from 18.8% (zinc) to 58.4% (fat) for nutrients; and for food group, 1.1% (Western fast foods) to 65.8% (soft drinks). In girls, these estimates ranged from 5.1% (total energy) to 38.7% (percentage of energy from fat) for nutrients, and 12.6% (eggs) to 94.6% (Western fast foods) for food groups. Factor analysis identified five food patterns: vegetables and fruits, fried and fast foods, beverages, snacks and meats. Maternal education and family income were positively associated with higher heritabilities for intake of meat, fried, and fast food.
  
  
  
  Genetic influence on dietary intakes differed by gender, nutrients, food groups, and dietary patterns among Chinese twins. Parental SES characteristics modified the estimated genetic influence.
authors.affiliation: Department of International Health, Johns Hopkins University Bloomberg School of Public Health,Baltimore,MD,USA.
authors.forename: Ji
authors.initials: J
authors.lastname: Li
authors.affiliation: Jiaxing Maternity and Child Health Care Hospital,Jiaxing,China.
authors.forename: Huijuan
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health,Baltimore,MD,USA.
authors.forename: Terri H
authors.initials: TH
authors.lastname: Beaty
authors.affiliation: Jiaxing Maternity and Child Health Care Hospital,Jiaxing,China.
authors.forename: Hua
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of International Health, Johns Hopkins University Bloomberg School of Public Health,Baltimore,MD,USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Caballero
authors.affiliation: Department of International Health, Johns Hopkins University Bloomberg School of Public Health,Baltimore,MD,USA.
authors.forename: Youfa
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D002648:Child; D004435:Eating / Q000235:genetics*; D002149:Energy Intake / Q000235:genetics*; D005260:Female; D005518:Food Preferences; D006801:Humans; D008297:Male; D008957:Models, Genetic; D012727:Sex Characteristics; D014429:Twins, Dizygotic / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*
keywords: China; children; dietary intake; heritability; twins