title: The first case of genetically confirmed monozygotic twinning in the dog.
abstract: Monozygotic twinning has not previously been genetically confirmed in the dog. This case report describes the finding of two viable male monozygotic foetuses within one placental site during caesarean section. Their umbilical cords attached to a single placenta. Genetic profiling using a total of 38 microsatellite markers, as well as amelogenin and SRY for sex determination, revealed identical DNA profiles, whether derived from blood or tissue (buccal swabs) samples. To the best of our knowledge, this is the first report of monozygotic twinning in the dog confirmed using DNA profiling.
authors.affiliation: Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa. carolynne.joone@jcu.edu.au.|Division of Tropical Health and Medicine, College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia. carolynne.joone@jcu.edu.au.
authors.forename: C J
authors.initials: CJ
authors.lastname: Joonè
authors.affiliation: Rant en Dal Animal Hospital, Mogale City, South Africa.
authors.forename: Kgm
authors.initials: K
authors.lastname: De Cramer
authors.affiliation: Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa.
authors.forename: J O
authors.initials: JO
authors.lastname: Nöthling
mesh_terms: D000818:Animals; D004247:DNA / Q000235:genetics; D004285:Dogs; D005260:Female; D008297:Male; D014430:Twins, Monozygotic / Q000235:genetics*
chemical_list: D004247:DNA