title: Expression patterns of miR-146a and miR-146b in mastitis infected dairy cattle.
abstract: This study reports a significant up-regulation of bta-miR-146a and bta-miR-146b expression levels in bovine mammary tissues infected with subclinical, clinical and experimental mastitis. Potential target genes are involved in multiple immunological pathways. These results suggest a regulatory function of both miRNAs for the bovine inflammatory response in mammary tissue.
authors.affiliation: College of Animal Science and Technology, National Beef Cattle Improvement Center, Northwest A&F University, Yangling, Shaanxi, China; Key Laboratory of Zoology in Hunan Higher Education, College of Life Science, Hunan University of Arts and Science, Changde, Hunan, China. Electronic address: huaswxp@hotmail.com.
authors.forename: Xing Ping
authors.initials: XP
authors.lastname: Wang
authors.affiliation: College of Animal Science and Technology, National Beef Cattle Improvement Center, Northwest A&F University, Yangling, Shaanxi, China; Key Laboratory of Zoology in Hunan Higher Education, College of Life Science, Hunan University of Arts and Science, Changde, Hunan, China.
authors.forename: Zhuo Ma
authors.initials: ZM
authors.lastname: Luoreng
authors.affiliation: College of Animal Science and Technology, National Beef Cattle Improvement Center, Northwest A&F University, Yangling, Shaanxi, China. Electronic address: zanlinsen@163.com.
authors.forename: Lin Sen
authors.initials: LS
authors.lastname: Zan
authors.affiliation: College of Animal Science and Technology, National Beef Cattle Improvement Center, Northwest A&F University, Yangling, Shaanxi, China.
authors.forename: Sayed Haidar Abbas
authors.initials: SH
authors.lastname: Raza
authors.affiliation: Key Laboratory of Zoology in Hunan Higher Education, College of Life Science, Hunan University of Arts and Science, Changde, Hunan, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.affiliation: Key Laboratory of Zoology in Hunan Higher Education, College of Life Science, Hunan University of Arts and Science, Changde, Hunan, China.
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.affiliation: Key Laboratory of Zoology in Hunan Higher Education, College of Life Science, Hunan University of Arts and Science, Changde, Hunan, China.
authors.forename: Shuan
authors.initials: S
authors.lastname: Liu
mesh_terms: D000818:Animals; D002417:Cattle / Q000097:blood / Q000235:genetics* / Q000382:microbiology*; D003612:Dairying; D005260:Female; D005786:Gene Expression Regulation; D008321:Mammary Glands, Animal / Q000378:metabolism / Q000382:microbiology / Q000473:pathology; D008414:Mastitis, Bovine / Q000097:blood / Q000235:genetics* / Q000382:microbiology; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism
chemical_list: D035683:MicroRNAs
keywords: Dairy cattle; Mastitis; miR-146a; miR-146b; microRNA