title: Electrochemical detection of single cancer and healthy cell collisions on a microelectrode.
abstract: The electrochemical detection of single cancer cells and healthy cells is reported. Detection was achieved by monitoring the consumption of a single cell's contents upon its collisions with a microelectrode in the presence of surfactant. The electrochemical response between acute lymphoblastic lymphoma T-cells and healthy thymocytes differed by two orders of magnitude.
authors.affiliation: Center for Electrochemistry, Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, USA. jedick@utexas.edu.
authors.forename: Jeffrey E
authors.initials: JE
authors.lastname: Dick
mesh_terms: D045744:Cell Line, Tumor; D003067:Coenzymes / Q000032:analysis / Q000378:metabolism; D055664:Electrochemical Techniques / Q000379:methods*; D006046:Gold / Q000737:chemistry; D006801:Humans; D008839:Microelectrodes; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000378:metabolism / Q000473:pathology; D017382:Reactive Oxygen Species / Q000032:analysis / Q000378:metabolism; D013501:Surface-Active Agents / Q000737:chemistry; D060168:Thymocytes / Q000166:cytology / Q000378:metabolism*
chemical_list: D003067:Coenzymes; D017382:Reactive Oxygen Species; D013501:Surface-Active Agents; D006046:Gold