title: Platelet function testing in cardiac surgery.
abstract: Bleeding in cardiac surgery is known to cause increased morbidity and mortality. The rise in the use of anti-platelet medication has led to an increase in the number of patients presenting for cardiac surgery with platelet dysfunction, who are at a heightened risk of bleeding. However, the extent of platelet inhibition is well known to differ among individuals. In the past few years, a number of point-of-care platelet function testing devices, which may be able to assess platelet reactivity, have entered the market. This review will examine the devices most commonly studied and the evidence surrounding their use in cardiac surgery and their effect on blood loss.
authors.affiliation: Department of Anaesthesia and Critical Care, Liverpool Heart and Chest Hospital, Liverpool, UK. Seema.Agarwal@lhch.nhs.uk.
authors.forename: S
authors.initials: S
authors.lastname: Agarwal
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001792:Blood Platelets / Q000378:metabolism*; D006348:Cardiac Surgical Procedures; D006801:Humans; D010979:Platelet Function Tests / Q000295:instrumentation / Q000379:methods
keywords: bleeding; cardiac surgery; platelet function