title: Core-shell poly(dopamine) magnetic nanoparticles for the extraction of estrogenic mycotoxins from milk and yogurt prior to LC-MS analysis.
abstract: In this work, core-shell poly(dopamine) magnetic nanoparticles synthesized in our laboratory have been applied as dispersive solid-phase extraction (dSPE) sorbent for the extraction of a group of six mycotoxins of interest including zearalenone, α-zearalanol, β-zearalanol, α-zearalenol, β-zearalenol and zearalanone, from complex matrices such as milk (whole and skimmed cow milk and semi-skimmed goat milk) and yogurt (an unsweetened natural yogurt) prior to their LC-MS analysis. 17β-estradiol-D5 was used as internal standard. The procedure includes a deproteinization step prior to the extraction procedure. Matrix-matched calibration and a recovery study were carried out in the selected matrices, providing good linearity, relative recovery values in the range 70-120% with RSDs lower than 16% and LODs between 0.21 and 4.77μg/L for milk samples and between 0.29 and 4.54μg/kg for yogurt samples.
authors.affiliation: Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Sección de Química, Universidad de La Laguna (ULL), Avenida Astrofísico Fco. Sánchez, s/n°. 38206 San Cristóbal de La Laguna, Tenerife, Islas Canarias, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: González-Sálamo
authors.affiliation: Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Sección de Química, Universidad de La Laguna (ULL), Avenida Astrofísico Fco. Sánchez, s/n°. 38206 San Cristóbal de La Laguna, Tenerife, Islas Canarias, Spain.
authors.forename: Bárbara
authors.initials: B
authors.lastname: Socas-Rodríguez
authors.affiliation: Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Sección de Química, Universidad de La Laguna (ULL), Avenida Astrofísico Fco. Sánchez, s/n°. 38206 San Cristóbal de La Laguna, Tenerife, Islas Canarias, Spain. Electronic address: jhborges@ull.edu.es.
authors.forename: Javier
authors.initials: J
authors.lastname: Hernández-Borges
authors.affiliation: Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Sección de Química, Universidad de La Laguna (ULL), Avenida Astrofísico Fco. Sánchez, s/n°. 38206 San Cristóbal de La Laguna, Tenerife, Islas Canarias, Spain.
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Rodríguez-Delgado
mesh_terms: D000818:Animals; D002417:Cattle; D002853:Chromatography, Liquid / Q000379:methods; D004967:Estrogens / Q000302:isolation & purification*; D005260:Female; D006041:Goats; D007211:Indoles; D057230:Limit of Detection; D058185:Magnetite Nanoparticles; D013058:Mass Spectrometry / Q000379:methods; D008892:Milk / Q000737:chemistry*; D009183:Mycotoxins / Q000302:isolation & purification*; D011108:Polymers; D015014:Yogurt / Q000032:analysis*
chemical_list: D004967:Estrogens; D007211:Indoles; D058185:Magnetite Nanoparticles; D009183:Mycotoxins; D011108:Polymers; C568283:polydopamine
keywords: Dispersive solid-phase extraction; LC–MS; Magnetic nanoparticles; Milk; Mycotoxin; Poly(dopamine)