title: Safety of Percutaneous Cryoablation in Patients with Painful Bone and Soft Tissue Tumors: A Single Center Prospective Study (SCIRO-1502).
abstract: This single center prospective study is being conducted to evaluate the safety of the cryoablation for patients with pathologically diagnosed painful bone and soft tissue tumors. Enrollment of 10 patients is planned over the 3-year recruitment period. Patients have related local pain after receiving medications or external radiation therapies will be included in this study. Cryoablation will be percutaneously performed under imaging guidance, and a temperature sensor will be used during treatment as necessary. The primary endpoint is prevalence of severe adverse events within 4 weeks after therapy. The secondary endpoint is effectiveness 4 weeks after the procedure.
authors.affiliation: Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Iguchi
authors.forename: Jun
authors.initials: J
authors.lastname: Sakurai
authors.forename: Takao
authors.initials: T
authors.lastname: Hiraki
authors.forename: Hideo
authors.initials: H
authors.lastname: Gobara
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Matsui
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Masaoka
authors.forename: Susumu
authors.initials: S
authors.lastname: Kanazawa
mesh_terms: D001859:Bone Neoplasms / Q000150:complications*; D002985:Clinical Protocols; D003452:Cryosurgery / Q000009:adverse effects*; D006801:Humans; D010146:Pain / Q000209:etiology*; D059408:Pain Management; D012107:Research Design; D012983:Soft Tissue Neoplasms / Q000150:complications*