title: A Case of Focal Bone Marrow Reconversion Mimicking Bone Metastasis: The Value of 111Indium Chloride.
abstract: We present a case of a 66-year-old man with esophageal carcinoma. 18Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for evaluating distant metastasis and staging revealed 18F-FDG uptake in the third lumbar vertebra and other vertebrae. Magnetic resonance imaging could not differentiate bone metastases from benign bone lesions. We considered the possibility of bone marrow reconversion. 111Indium chloride (111In-Cl3) scintigraphy with single-photon emission computed tomography/computed tomography (SPECT/CT) revealed erythroid bone marrow components in the bone lesions. The diagnosis of bone marrow reconversion was pathologically confirmed by a bone biopsy of the third lumbar vertebra. The patient underwent esophagectomy and has remained disease-free in the 2 years since. To the best of our knowledge, this is the first report to describe the usefulness of 111In-Cl3 with SPECT/CT for the diagnosis of bone marrow reconversion.
authors.affiliation: Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.p9r543qa@s.okayama-u.ac.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tanaka
authors.forename: Hideo
authors.initials: H
authors.lastname: Gobara
authors.forename: Ryota
authors.initials: R
authors.lastname: Inai
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Iguchi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tada
authors.forename: Shuhei
authors.initials: S
authors.lastname: Sato
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yanai
authors.forename: Susumu
authors.initials: S
authors.lastname: Kanazawa
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D019046:Bone Marrow Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D002277:Carcinoma / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007204:Indium / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D000072078:Positron Emission Tomography Computed Tomography; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D007204:Indium; D019788:Fluorodeoxyglucose F18; C020758:indium trichloride