title: Characteristics of a novel polymer gel dosimeter formula for MRI scanning: Dosimetry, toxicity and temporal stability of response.
abstract: The present study intended to investigate the composition of a new polymer gel dosimeter. The new composition would be more suitable for a wide range of applications in comparison to polyacrylamide gel dosimeter since its extremely toxic acrylamide has been replaced with less harmful monomer i.e. 2-Acrylamido-2-MethylPropane Sulfonic acid (AMPS). To this end, the PAGAT gel dosimeter formula was used as a basis to test the new formulation of polymer gel dosimeter with a different monomer (AMPS) instead of acrylamide by using the %6T and %50C to the formula. The new formulation was named PAMPSGAT (Poly AMPS, Gelatin and THPC) polymer gel dosimeter. Moreover, the MRI response (R2) of dosimeters was analyzed in terms of different dose range as well as post-irradiation time. The results indicated that the dose-response (R2) of AMPS/Bis had a linear trend over a wide dose range. Furthermore, the results showed an acceptable temporal stability for the new polymer gel dosimeter.
authors.affiliation: Physics Department, Imam Khomeini International University, Qazvin P.O. Box: 34149-16818, Iran. Electronic address: smabtahi2007@gmail.com.
authors.forename: S M
authors.initials: SM
authors.lastname: Abtahi
mesh_terms: D020106:Acrylamide / Q000737:chemistry; D000178:Acrylamides / Q000737:chemistry; D000180:Acrylic Resins; D000476:Alkanesulfonates / Q000737:chemistry; D000818:Animals; D000975:Antioxidants / Q000737:chemistry; D005780:Gelatin / Q000737:chemistry; D005782:Gels; D006801:Humans; D016014:Linear Models; D008279:Magnetic Resonance Imaging; D009498:Neurotoxins / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D000072232:Radiation Dosimeters; D011874:Radiometry / Q000379:methods*; D051381:Rats; D013696:Temperature; D013997:Time Factors
chemical_list: D000178:Acrylamides; D000180:Acrylic Resins; D000476:Alkanesulfonates; D000975:Antioxidants; D005782:Gels; D009498:Neurotoxins; D009943:Organophosphorus Compounds; D011108:Polymers; C016680:polyacrylamide gels; C014850:tetramethylolphosphonium chloride; D020106:Acrylamide; C056288:2-acrylamido-2-methylpropanesulfonate; D005780:Gelatin
keywords: 2-Acrylamido-2-MethylPropane Sulfonic acid; MRI; PAMPSGAT; Polymer gel dosimeter