title: Two new 5-deoxyflavan-3,4-diol glucosides from roots of Albizia chevalieri.
abstract: Phytochemical investigation of the roots of Albizia chevalieri led to the isolation of two new 5-deoxyflavan-3,4-diol glucosides from roots of A. chevalieri, Chevalieriflavanosides A and B. Their structures were established by 2D NMR techniques, UV, IR, CD, and mass spectrometry. Cytotoxicity of the two compounds was evaluated against acute promyelocytic leukemia HL60 cells. The antibacterial activities of 1 and 2 also were evaluated against Pseudomonas aeruginosa and Staphylococcus aureus using the agar diffusion test. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Département de Chimie Organique, Université de Yaoundé 1, Yaoundé, Cameroun.|Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, Japan.
authors.forename: Abdou
authors.initials: A
authors.lastname: Tchoukoua
authors.affiliation: Département de Chimie Organique, Université de Yaoundé 1, Yaoundé, Cameroun. ttabopda@yahoo.fr.
authors.forename: Turibio
authors.initials: T
authors.lastname: Kuiate Tabopda
authors.affiliation: The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan.
authors.forename: Shota
authors.initials: S
authors.lastname: Uesugi
authors.affiliation: The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan.
authors.forename: Ken-Ichi
authors.initials: KI
authors.lastname: Kimura
authors.affiliation: Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Sendai, Miyagi, Japan.
authors.forename: Eunsang
authors.initials: E
authors.lastname: Kwon
authors.affiliation: Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Sendai, Miyagi, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Momma
authors.affiliation: Département de Chimie Organique, Université de Yaoundé 1, Yaoundé, Cameroun. ngadjuibt@yahoo.fr.
authors.forename: Bonaventure Tchaleu
authors.initials: BT
authors.lastname: Ngadjui
authors.affiliation: Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Koseki
authors.affiliation: Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata, Japan. yshiono@tds1.tr.yamagata-u.ac.jp.
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Shiono
mesh_terms: D031289:Albizzia / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D002942:Circular Dichroism; D004354:Drug Screening Assays, Antitumor; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D008968:Molecular Conformation; D010936:Plant Extracts; D018517:Plant Roots / Q000737:chemistry; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D005960:Glucosides; D010936:Plant Extracts; C000626151:chevalieriflavanoside A; C000626152:chevalieriflavanoside B
keywords: 13C; 1H; Albizia chevalieri; Leguminosae; NMR; cytotoxicity; flavan-3,4-diols