title: Pancreatic Cancer: A Review.
abstract: Pancreatic cancer is now the third leading cause of cancer related deaths in the United States, yet advances in treatment options have been minimal over the past decade. In this review, we summarize the evaluation and treatments for this disease. We highlight molecular advances that hopefully will soon translate into improved outcomes.
authors.affiliation: Department of Surgery, Thomas Jefferson University Hospital, Sidney Kimmel Medical College, 1015 Walnut Street, Curtis Building, Suite 620, Philadelphia, PA 19107, USA.
authors.forename: Cinthya S
authors.initials: CS
authors.lastname: Yabar
authors.affiliation: Department of Surgery, Thomas Jefferson University Hospital, Sidney Kimmel Medical College, 1015 Walnut Street, Curtis Building, Suite 620, Philadelphia, PA 19107, USA. Electronic address: Jordan.Winter@jefferson.edu.
authors.forename: Jordan M
authors.initials: JM
authors.lastname: Winter
mesh_terms: D000367:Age Factors; D000970:Antineoplastic Agents / Q000627:therapeutic use; D024682:BRCA2 Protein / Q000235:genetics; D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D055088:Early Detection of Cancer; D019160:Endosonography; D052218:Fanconi Anemia Complementation Group C Protein / Q000235:genetics; D052241:Fanconi Anemia Complementation Group G Protein / Q000235:genetics; D000076164:Fanconi Anemia Complementation Group N Protein; D006801:Humans; D009687:Nuclear Proteins / Q000235:genetics; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D050500:Pancreatitis, Chronic / Q000453:epidemiology; D000067856:Poly(ADP-ribose) Polymerase Inhibitors / Q000627:therapeutic use; D000072078:Positron Emission Tomography Computed Tomography; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics; D012907:Smoking / Q000453:epidemiology; D014057:Tomography, X-Ray Computed; D016159:Tumor Suppressor Protein p53 / Q000235:genetics; D025521:Tumor Suppressor Proteins / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; D024682:BRCA2 Protein; C551750:BRCA2 protein, human; C497651:FANCC protein, human; C499909:FANCG protein, human; D052218:Fanconi Anemia Complementation Group C Protein; D052241:Fanconi Anemia Complementation Group G Protein; D000076164:Fanconi Anemia Complementation Group N Protein; C117307:KRAS protein, human; D009687:Nuclear Proteins; C512790:PALB2 protein, human; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; D025521:Tumor Suppressor Proteins; D016283:Proto-Oncogene Proteins p21(ras)
keywords: Evaluation; Pancreatic cancer; Pancreatic ductal adenocarcinoma; Treatment