title: Compression versus No Compression after Endovenous Ablation of the Great Saphenous Vein: A Randomized Controlled Trial.
abstract: BACKGROUND
  The goal of this study is to determine if compression therapy after endovenous ablation (EVA) of the great saphenous vein (GSV) improves efficacy and patient-reported outcomes of pain, ecchymosis, and quality of life.
  
  
  METHODS
  This is a prospective randomized controlled trial from 2009 to 2013 comparing the use of thigh-high 30-40 mm Hg compression therapy for 7 days versus no compression therapy following EVA of the GSV. Severity of venous disease was measured by clinical severity, etiology, anatomy, pathophysiology scale and the Venous Clinical Severity Score (VCSS). Quality of life assessments were carried out with a Chronic Venous Insufficiency Questionnaire (CIVIQ-2) at days 1, 7, 14, 30, and 90, and the Visual Analog Pain Scale daily for the first week. Bruising score was assessed at 1 week post procedure. Postablation venous duplex was also performed.
  
  
  RESULTS
  Seventy patients and 85 limbs with EVA were randomized. EVA modalities included radiofrequency ablation (91%) and laser ablation (9%). Clinical severity, etiology, anatomy, pathophysiology class and VCSS scores were equivalent between the 2 groups. There was no significant difference in patient-reported outcomes of postprocedural pain scores at day 1 (mean 3.0 vs. 3.12, P = 0.948) and day 7 (mean 2.11 vs. 2.81, P = 0.147), CIVIQ-2 scores at 1 week (mean 36.9 vs. 35.1, P = 0.594) and 90 days (mean 29.1 vs. 22.5, P = 0.367), and bruising score (mean 1.2 vs. 1.4, P = 0.561) in the compression versus no compression groups, respectively. Additionally, there was a 100% rate of GSV closure in both groups and no endothermal heat-induced thrombosis as assessed by postablation duplex.
  
  
  CONCLUSIONS
  Compression therapy does not significantly affect both patient-reported and clinical outcomes after GSV ablation in patients with nonulcerated venous insufficiency. It may be an unnecessary adjunct following GSV ablation.
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY. Electronic address: diego.ayo@nyumc.org.
authors.forename: Diego
authors.initials: D
authors.lastname: Ayo
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Sheila N
authors.initials: SN
authors.lastname: Blumberg
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Caron R
authors.initials: CR
authors.lastname: Rockman
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Mikel
authors.initials: M
authors.lastname: Sadek
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Neal
authors.initials: N
authors.lastname: Cayne
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Mark
authors.initials: M
authors.lastname: Adelman
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Lowell
authors.initials: L
authors.lastname: Kabnick
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Thomas
authors.initials: T
authors.lastname: Maldonado
authors.affiliation: Division of Vascular and Endovascular Surgery, NYU Langone Medical Center, New York, NY.
authors.forename: Todd
authors.initials: T
authors.lastname: Berland
mesh_terms: D058128:Compression Bandages; D004438:Ecchymosis / Q000209:etiology; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009519:New York City; D010147:Pain Measurement; D010149:Postoperative Pain / Q000209:etiology; D011312:Pressure; D011446:Prospective Studies; D011788:Quality of Life; D012501:Saphenous Vein / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D014689:Venous Insufficiency / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*