title: Brainstem Glioma in Adults.
abstract: Brainstem gliomas are not nearly as common in adults as they are in children. They are likely the final common consequence not of a single disease process but of several. They can be difficult to diagnose, and are challenging to treat. Clinical studies of this diagnosis are few and generally small. Because of these factors, our understanding of the biology of adult brainstem glioma is incomplete. However, the knowledge base is growing and progress is being made. In this article, we review the current state of knowledge for brainstem glioma in adults and identify key areas for which additional information is required.
authors.affiliation: Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Jethro
authors.initials: J
authors.lastname: Hu
authors.affiliation: Independent Researcher, Vancouver, Canada.
authors.forename: Stephen
authors.initials: S
authors.lastname: Western
authors.affiliation: Department of Translational Neuro-Oncology and Neurotherapeutics, John Wayne Cancer Institute, Pacific Neuroscience Institute, Providence Saint John's Health Center , Santa Monica, CA , USA.
authors.forename: Santosh
authors.initials: S
authors.lastname: Kesari
keywords: DIPG; IDH mutations; glioma