title: Diagnosis and treatment of pulmonary alveolar microlithiasis.
abstract: Pulmonary alveolar microlithiasis (PAM) is a rare genetic disease caused by mutations in sodium-phosphate co-transporter (SLC34A2), which encodes a type 2b sodium phosphate co-transporter. Disease is characterized by intra-alveolar microlith formation of phosphate. Turkey has a high prevalence of PAM. Herein, we report the clinical and radiological findings of three patients diagnosed with PAM and treated with disodium etidronate.
authors.affiliation: Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Nagehan
authors.initials: N
authors.lastname: Emiralioglu
authors.affiliation: Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Burcin
authors.initials: B
authors.lastname: Beken
authors.affiliation: Department of Pediatric Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Hatice Nursun
authors.initials: HN
authors.lastname: Ozcan
authors.affiliation: Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Ebru
authors.initials: E
authors.lastname: Yalcin
authors.affiliation: Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Dogru
authors.affiliation: Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Ozcelik
authors.affiliation: Department of Pediatric Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Mithat
authors.initials: M
authors.lastname: Haliloglu
authors.affiliation: Department of Pediatric Pulmonology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Nural
authors.initials: N
authors.lastname: Kiper
mesh_terms: D000293:Adolescent; D001706:Biopsy; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002114:Calcinosis / Q000175:diagnosis* / Q000188:drug therapy; D002648:Child; D012968:Etidronic Acid / Q000627:therapeutic use*; D030342:Genetic Diseases, Inborn / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011650:Pulmonary Alveoli / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D050071:Bone Density Conservation Agents; D012968:Etidronic Acid
keywords: diagnostic imaging; disodium etidronate; pulmonary alveolar microlithiasis