title: [Asteatotic eczema as paraneoplastic syndrome].
abstract: Asteatotic eczema is rarely associated with an underlying malignancy. The condition as paraneoplastic syndrome is characterised by glucocorticoid resistance.
  
  
  
  A 66-year old woman came to the emergency room with symptoms of dehydration resulting from diarrhoea due to cyclosporine therapy for treatment-resistant eczema. CT scan of thorax and abdomen showed multiple, pathologically enlarged lymph nodes. Histological examination of a lymph node biopsy from the right axilla showed an ALK-negative, anaplastic large T-cell lymphoma.
  
  
  
  Asteatotic eczema is usually innocuous but may also be linked to malignancy. A careful physical examination and early referral to second-line care are needed for rapid diagnosis and treatment of the underlying condition.
authors.affiliation: Franciscus Gasthuis & Vlietland, locatie Gasthuis, Rotterdam.
authors.forename: N
authors.initials: N
authors.lastname: Koks
authors.forename: Y J
authors.initials: YJ
authors.lastname: Assen
authors.forename: E J
authors.initials: EJ
authors.lastname: Libourel
authors.forename: S A
authors.initials: SA
authors.lastname: Eskes
mesh_terms: D000368:Aged; D001365:Axilla / Q000000981:diagnostic imaging; D001706:Biopsy; D016572:Cyclosporine / Q000627:therapeutic use; D004485:Eczema / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D016572:Cyclosporine