title: [CLINICAL AND X-RAY CHARACTERISTICS AND THERAPEUTIC EFFICIENCY IN PATIENTS WITH INFILTRATIVE PULMONARY TUBERCULOSIS AND VARIOUS AUTONOMIC HOMEOSTATIC CHANGES].
abstract: To study the course of the disease and the efficiency of treatment, 100 patients with infiltrative pulmonary tuberculosis and different types of autonomic homeostasis were followed up. A cardiac rhythm variability study revealed normotonia in 24 patients (Group 1), vagotonia in 36 (Group 2), and sympathocotonia in 40 (Group 3). The subjects with baseline sympathocotonia more frequently showed disseminated processes (involving 2 lung lobes or more) with bacterial excretion, and adverse reactions caused by antituberculosis drugs. The most pronounced changes in total responsiveness and its negative dynamics during treatment are unique to the patients of this group. In the latter, therapeutic efficiency is in terms of decay cavity closure significantly lower (34.3%) than that in the patients with baseline normotonia (72.1%), which requires that a correction scheme for autonomic disorders should be developed.
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001341:Autonomic Nervous System / Q000503:physiopathology*; D005260:Female; D006706:Homeostasis; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012720:Severity of Illness Index; D013223:Statistics as Topic; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
chemical_list: D000995:Antitubercular Agents