title: Trends and challenges in immuno-oncology trials.
abstract: Immuno-oncology (I/O) is changing the way that we approach cancer therapy. As precision medicine comes to the forefront, clinical researchers are beginning to home in on tumors with targeted therapies, focusing on those that have been previously resistant to treatment. This has been accom¬plished with chemical agents in small cancer subsets; how¬ever, immunotherapy seeks to harness the mechanisms of our own immune system to target cancer and its pathways.
authors.affiliation: Thomson Reuters, Portland, Maryland, USA. scientific.prousjournals@thomsonreuters.com.
authors.forename: B
authors.initials: B
authors.lastname: Kiernan
mesh_terms: D000486:Allergy and Immunology / Q000639:trends*; D000818:Animals; D019496:Cancer Vaccines; D059447:Cell Cycle Checkpoints / Q000187:drug effects*; D006801:Humans; D007167:Immunotherapy; D008495:Medical Oncology / Q000639:trends*; D009369:Neoplasms / Q000276:immunology / Q000517:prevention & control* / Q000628:therapy*; D057285:Precision Medicine
chemical_list: D019496:Cancer Vaccines
keywords: Cancer vaccines; Checkpoint inhibitors; Immuno-oncology