title: Expanded Endonasal Endoscopic Approach for Resection of an Infrasellar Craniopharyngioma.
abstract: BACKGROUND
  Craniopharyngiomas are uncommon benign locally aggressive epithelial tumors mostly located in the sellar and suprasellar regions. An infrasellar origin of these tumors is rare.
  
  
  METHODS
  The authors report a 22-year-old male patient with a purely infrasellar adamantinomatous craniopharyngioma centered in the nasopharynx with extension into the posterior nasal septum, sphenoid sinus, and clivus. Gross total resection was achieved using an expanded endonasal endoscopic transethmoidal, transsphenoidal, transpterygoid, and transclival approach. Follow-up at one year demonstrated no evidence of disease recurrence.
  
  
  CONCLUSIONS
  Infrasellar craniopharyngioma should be included in the differential diagnosis of sinonasal masses even in the absence of sellar extension. Expanded endonasal endoscopic approaches provide excellent access to and visualization of such lesions and may obviate the need for postoperative radiotherapy when gross total resection is achieved.
authors.affiliation: College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
authors.forename: Hussam
authors.initials: H
authors.lastname: Abou-Al-Shaar
authors.affiliation: Division of Neuroradiology, Department of Radiology and Radiologic Science, Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Ari M
authors.initials: AM
authors.lastname: Blitz
authors.affiliation: Division of Neuropathology, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Fausto J
authors.initials: FJ
authors.lastname: Rodriguez
authors.affiliation: Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: Masaru
authors.initials: M
authors.lastname: Ishii
authors.affiliation: Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA; Department of Oncology, Johns Hopkins Hospital, Baltimore, Maryland, USA; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: ggallia1@jhmi.edu.
authors.forename: Gary L
authors.initials: GL
authors.lastname: Gallia
mesh_terms: D003388:Cranial Fossa, Posterior / Q000000981:diagnostic imaging / Q000601:surgery; D003397:Craniopharyngioma / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009296:Nasal Cavity / Q000000981:diagnostic imaging / Q000601:surgery; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D057605:Natural Orifice Endoscopic Surgery; D044583:Neuroendoscopy / Q000379:methods*; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D013101:Sphenoid Sinus / Q000000981:diagnostic imaging / Q000601:surgery; D014057:Tomography, X-Ray Computed; D055815:Young Adult
keywords: Adamantinoma; Craniopharyngioma; Expanded endonasal endoscopic approach; Infrasellar; Nasopharynx