title: Facial Dermatitis and Rosacea.
abstract: Rosacea is a chronic skin disorder associated with flushing, erythema, dryness, burning and stinging, and inflammatory papules and pustules. New treatments available or in development target the inflammatory and erythematous components of the disease. These agents include the selective α2 receptor agonist brimonidine, the topical agents ivermectin cream 1% and azelaic acid foam 15%, and use of tetracyclinetype antibiotics, which affect the cathelicidin pathway. Semin Cutan Med Surg 35(supp6):S107-S109.
authors.affiliation: Assistant Professor of Dermatology Tufts University School of Medicine Director, Psoriasis Treatment Center SkinCare Physicians Chestnut Hill, Massachusetts.
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Fowler
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D058647:Adrenergic alpha-2 Receptor Agonists / Q000627:therapeutic use; D023181:Antimicrobial Cationic Peptides / Q000378:metabolism; D000977:Antiparasitic Agents / Q000627:therapeutic use; D000068438:Brimonidine Tartrate / Q000627:therapeutic use; D003872:Dermatitis / Q000188:drug therapy* / Q000378:metabolism; D003879:Dermatologic Agents / Q000627:therapeutic use*; D003998:Dicarboxylic Acids / Q000627:therapeutic use; D005148:Facial Dermatoses / Q000188:drug therapy*; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D012393:Rosacea / Q000188:drug therapy* / Q000378:metabolism; D054804:Cathelicidins
chemical_list: D000305:Adrenal Cortex Hormones; D058647:Adrenergic alpha-2 Receptor Agonists; D023181:Antimicrobial Cationic Peptides; D000977:Antiparasitic Agents; D003879:Dermatologic Agents; D003998:Dicarboxylic Acids; D000068438:Brimonidine Tartrate; D007559:Ivermectin; C010038:azelaic acid; D054804:Cathelicidins
keywords: Azelaic acid; brimonidine; cathelicidin; ivermectin; rosacea