title: Usefulness of the monocyte-to-high-density lipoprotein cholesterol ratio to predict bare metal stent restenosis.
abstract: OBJECTIVE
  The aim of the present study was to investigate the predictive value of preprocedural monocyte count-to-high-density lipoprotein cholesterol ratio (MHR) on development of in-stent restenosis in patients undergoing coronary bare-metal stent (BMS) implantation.
  
  
  METHODS
  Data from 705 patients who had undergone BMS implantation and additional control coronary angiography were analyzed.
  
  
  RESULTS
  Patients were divided into three tertiles based on preprocedural MHR. Restenosis occurred in 59 patients (25%) in the lowest tertile, 84 (35%) in the middle tertile and 117 (50%) in the highest MHR tertile (p < 0.001). Using multiple logistic regression analysis, smoking, diabetes mellitus, stent length, preprocedural MHR and C-reactive protein levels emerged as independent predictors of in-stent restenosis.
  
  
  CONCLUSIONS
  High preprocedural MHR is related to BMS restenosis.
authors.affiliation: Cardiovascular Department, Yozgat State Hospital, 66200 Yozgat, Turkey.
authors.forename: Samet
authors.initials: S
authors.lastname: Yilmaz
authors.affiliation: Cardiology Clinic, Turkey Yuksek Ihtisas Education & Research Hospital, 06100 Ankara, Turkey.
authors.forename: Mehmet K
authors.initials: MK
authors.lastname: Akboga
authors.affiliation: Cardiology Clinic, Turkey Yuksek Ihtisas Education & Research Hospital, 06100 Ankara, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Sen
authors.affiliation: Cardiology Clinic, Turkey Yuksek Ihtisas Education & Research Hospital, 06100 Ankara, Turkey.
authors.forename: Kevser G
authors.initials: KG
authors.lastname: Balcı
authors.affiliation: Cardiology Clinic, Turkey Yuksek Ihtisas Education & Research Hospital, 06100 Ankara, Turkey.
authors.forename: Dursun
authors.initials: D
authors.lastname: Aras
authors.affiliation: Cardiology Clinic, Turkey Yuksek Ihtisas Education & Research Hospital, 06100 Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temizhan
authors.affiliation: Cardiology Clinic, Turkey Yuksek Ihtisas Education & Research Hospital, 06100 Ankara, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Aydogdu
mesh_terms: D000368:Aged; D019540:Area Under Curve; D002097:C-Reactive Protein / Q000032:analysis; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000166:cytology; D016017:Odds Ratio; D011237:Predictive Value of Tests; D012372:ROC Curve; D015607:Stents
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D002097:C-Reactive Protein
keywords: high-density lipoprotein cholesterol; inflammation; monocyte count; stent restenosis