title: [Two Cases of Gastric Endocrine Cell Carcinoma].
abstract: The first patient was a man in his eighties who visited our department because of anemia. Gastrofiberscopy revealed a bleeding submucosal tumor, approximately 50mm in diameter, in the cardia ofthe stomach. Considering that he underwent coronary-artery bypass surgery and received 3 oral antithrombotic medicines, his bleeding tendency was so high that we decided to choose partial gastrectomy. A postoperative histopathological examination revealed that the tumor was a small cell endocrine carcinoma. The second patient was a woman in her seventies. She had consulted her personal physician because of gastric ulcers; periodic gastrofiberscopy revealed a type 3 gastric cancer, approximately 40mm in diameter, on the posterior wall ofthe middle section ofher stomach. It was histologically diagnosed as a poorly differentiated neuroendocrine carcinoma. On a preoperative blood examination, the levels ofhormones such as glucagon, serotonin, and gastrin were within their respective normal limits. Total gastrectomy was performed, and she received oral S-1 for adjuvant chemotherapy since her discharge from the hospital.
authors.affiliation: Dept. of Surgery, Yokohama Sakae Kyosai Hospital.
authors.forename: Masataka
authors.initials: M
authors.lastname: Tochimoto
authors.forename: Toru
authors.initials: T
authors.lastname: Watanabe
authors.forename: Karin
authors.initials: K
authors.lastname: Sadamura
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Iwaki
authors.forename: Yuta
authors.initials: Y
authors.lastname: Horiguchi
authors.forename: Kanae
authors.initials: K
authors.lastname: Tawaraya
authors.forename: Hideaki
authors.initials: H
authors.lastname: Katoh
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kawaguchi
authors.forename: Osamu
authors.initials: O
authors.lastname: Hosokawa
authors.forename: Kunio
authors.initials: K
authors.lastname: Yanagimoto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018278:Carcinoma, Neuroendocrine / Q000188:drug therapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery