title: Cognitive function assessment in patients with end- stage renal disease in Nigeria: A single center experience.
abstract: OBJECTIVE
  The purpose of this comparative study was to evaluate cognitive function in end-stage renal disease (ESRD) patients in comparison with age, sex, and level of education-matched control.
  
  
  METHODS
  This is a cross-sectional study involving 80 ESRD patients receiving maintenance hemodialysis treatment and recruited conservatively at the nephrology unit of our hospital. Eighty apparently healthy control, that were matched with the patients for age, sex and education, were also recruited. Following exclusion of depression and severe functional disability, a computer-assisted neuropsychological test, the FePsy, was used to assess  memory, psychomotor speed, concentration and attention using simple auditory and visual reaction time tasks, recognition memory tests (RMTs), finger tapping task, and binary choice task (BCT) for both the ESRD patients and controls.
  
  
  RESULTS
  ESRD patients performed worse on simple auditory and visual reaction time tasks (P < 0.05), RMTs (P < 0.05), finger tapping task (P < 0.05), BCT, and computerized visual search task (P < 0.05).
  
  
  CONCLUSIONS
  Performance in memory, psychomotor tasks, concentration, and attention tasks were found to be reduced among patients with ESRD compared with age, sex and level of education-matched control.
authors.affiliation: Department of Neurology, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
authors.forename: Lukman Femi
authors.initials: LF
authors.lastname: Owolabi
authors.affiliation: Department of Nephrology, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
authors.forename: Aliyu
authors.initials: A
authors.lastname: Abdu
authors.affiliation: Department of Neurology, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
authors.forename: Aliyu
authors.initials: A
authors.lastname: Ibrahim
authors.affiliation: Department of Psychiatry, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
authors.forename: Desola Shakira
authors.initials: DS
authors.lastname: Owolabi
authors.affiliation: Department of Nephrology, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
authors.forename: Aisha
authors.initials: A
authors.lastname: Nalado
authors.affiliation: Department of Nephrology, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
authors.forename: Adamu
authors.initials: A
authors.lastname: Bappa
authors.affiliation: Department of Psychiatry, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
authors.forename: Aminu Abdullahi
authors.initials: AA
authors.lastname: Taura
mesh_terms: D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D003071:Cognition; D003072:Cognition Disorders / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000503:physiopathology / Q000523:psychology*; D008297:Male; D008568:Memory; D009483:Neuropsychological Tests; D009549:Nigeria; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*; D012737:Sex Factors; D012959:Socioeconomic Factors