title: Simultaneous Near-Infrared and Two-Photon In Vivo Imaging of H2O2Using a Ratiometric Fluorescent Probe based on the Unique Oxidative Rearrangement of Oxonium.
abstract: A new ratiometric fluorescent H2O2probe, benzopyrylium-coumarin (BC), is designed by using an oxonium moiety as the unique H2O2response site. The BC probe exhibits an extremely large emission shift of 221 nm in response to H2O2, and is successfully applied for the simultaneous near-infrared and two-photon imaging of H2O2in living cells, mouse-liver tissues, and zebrafish.
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, P. R. China.
authors.forename: Baoli
authors.initials: B
authors.lastname: Dong
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, P. R. China.
authors.forename: Xuezhen
authors.initials: X
authors.lastname: Song
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, P. R. China.
authors.forename: Xiuqi
authors.initials: X
authors.lastname: Kong
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, P. R. China.
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, P. R. China.
authors.forename: Yonghe
authors.initials: Y
authors.lastname: Tang
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, P. R. China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Institute of Fluorescent Probes for Biological Imaging, School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, University of Jinan, Shandong, 250022, P. R. China. weiyinglin2013@163.com.|State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Hunan, 410082, P. R. China. weiyinglin2013@163.com.
authors.forename: Weiying
authors.initials: W
authors.lastname: Lin
mesh_terms: D000818:Animals; D002470:Cell Survival; D005456:Fluorescent Dyes; D051379:Mice; D018384:Oxidative Stress; D017785:Photons
chemical_list: D005456:Fluorescent Dyes
keywords: fluorescent probes; hydrogen peroxide; near-infrared imaging; oxidative rearrangement of oxonium; two-photon imaging