title: Ruminal Leiomyosarcoma in an adult cow.
abstract: An ulcerated and pedunculated intraluminal yellowish solitary mass was observed protruding into the ruminal lumen of an adult cow during an abattoir survey. Histologically, the neoplasm invaded the lamina propria-submucosa, eroded the ruminal epithelium and segmentally effaced the inner tunica muscularis. It was composed of pleomorphic spindle cells arranged in fascicles. Areas of hemorrhage, necrosis, microcystic changes as well as marked anisokaryosis, the presence of giant cells and scattered mitosis with atypical figures, were also observed. Immunohistochemically this tumor labeled positive for alpha smooth muscle actin, desmin and vimentin. With all the above findings, a diagnosis of ruminal leiomyosarcoma was confirmed. To the authors' knowledge, this is the first report of ruminal leiomyosarcoma in cattle.
authors.forename: Julio
authors.initials: J
authors.lastname: Benavides
authors.forename: Miguel
authors.initials: M
authors.lastname: Fuertes
authors.forename: Valentin
authors.initials: V
authors.lastname: Pérez
authors.forename: Laetitia
authors.initials: L
authors.lastname: Delgado
authors.forename: Ma Carmen
authors.initials: MC
authors.lastname: Ferreras
mesh_terms: D000003:Abattoirs; D000199:Actins / Q000032:analysis; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D007890:Leiomyosarcoma / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D012417:Rumen / Q000473:pathology*; D013274:Stomach Neoplasms / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D003893:Desmin; D014746:Vimentin