title: Optical Modulation of Azobenzene-Modified Peptide for Gold Surface Binding.
abstract: The ability to precisely and remotely modulate reversible binding interactions between biomolecules and abiotic surfaces is appealing for many applications. To achieve this level of control, an azobenzene-based optical switch is added to nanoparticle-binding peptides in order to switch peptide conformation and attenuate binding affinity to gold surfaces via binding and dissociation of peptides.
authors.affiliation: Soft Matter Materials Branch, Materials and Manufacturing Directorate, Air Force Research Laboratory, Dayton, OH, 45433, USA.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Slocik
authors.affiliation: Soft Matter Materials Branch, Materials and Manufacturing Directorate, Air Force Research Laboratory, Dayton, OH, 45433, USA.
authors.forename: Zhifeng
authors.initials: Z
authors.lastname: Kuang
authors.affiliation: Department of Chemistry, Miami University, Miami, FL, 33146, USA.
authors.forename: Marc R
authors.initials: MR
authors.lastname: Knecht
authors.affiliation: 711th Human Performance Wing, Air Force Research Laboratory, Dayton, OH, 45433, USA. rajesh.naik@us.af.mil.
authors.forename: Rajesh R
authors.initials: RR
authors.lastname: Naik
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D001665:Binding Sites; D006046:Gold / Q000737:chemistry*; D055620:Optical Phenomena; D010455:Peptides / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D001391:Azo Compounds; D010455:Peptides; D006046:Gold; C009850:azobenzene
keywords: azobenzene; bionanotechnology; gold nanoparticles; peptides; phage display