title: An enterovirus from a captive primate in China.
abstract: BACKGROUND
  Enteroviruses (EVs) are a genetically and antigenically diverse group of viruses infecting humans and a variety of animals including non-human primates (NHPs). The present study was to investigate EVs in the fecal samples from captive NHPs in zoos in China using classic RT-PCR and viral metagenomics methods.
  
  
  RESULTS
  An EV strain was detected in a fecal sample collected from a captive NHP of a zoo in eastern China. The complete genome of this EV strain (named Sev-nj1) was determined and characterized. Sequence analysis indicated Sev-nj1 shared the highest sequence identity (75.6 %) with an EV-J strain, Poo-1, based on the complete genome. Phylogenetic analysis showed Sev-nj1 clustered with the other EV-J strains, forming a separate clade.
  
  
  CONCLUSIONS
  According to the genetic distance-based criteria, Sev-nj1 belonged to a new type within the species EV-J. This is the first study detecting EV-J from a NHP in China, which will be helpful for the future epidemiology study of EVs in NHPs.
authors.affiliation: Department of Pathogenic Biology, School of Medical Science, Jiangsu University, Zhenjiang, 212013 Jiangsu China.
authors.forename: Xiaochun
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Pathogenic Biology, School of Medical Science, Jiangsu University, Zhenjiang, 212013 Jiangsu China.
authors.forename: Shihe
authors.initials: S
authors.lastname: Shao
authors.affiliation: Department of Pathogenic Biology, School of Medical Science, Jiangsu University, Zhenjiang, 212013 Jiangsu China.
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Pathogenic Biology, School of Medical Science, Jiangsu University, Zhenjiang, 212013 Jiangsu China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Shen
authors.affiliation: Department of Pathogenic Biology, School of Medical Science, Jiangsu University, Zhenjiang, 212013 Jiangsu China.
authors.forename: Shixing
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of Pathogenic Biology, School of Medical Science, Jiangsu University, Zhenjiang, 212013 Jiangsu China.
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
keywords: EV-J; Enterovirus; Non-human primate; Phylogenetic analysis; Viral metagenomics