title: The journey toward safer and optimized blood service in China: national strategy and progress.
abstract: The objective was to analyze and evaluate the effects of strategic measures the Chinese government attempted and undertook throughout the fast-changing and difficult transition periods of the blood service system.
  
  
  
  We systematically reviewed data and information regarding policy, blood collection, service system, and clinical transfusion practice, which were the most representative indicators on a national level from 1978 to 2015.
  
  
  
  Blood donation in China has successfully transitioned from paid donation, then compulsory (but nonremunerated) donation, to voluntary nonremunerated donation. The volume of blood collection has steadily increased from 4,000,000 red blood cell (RBC; 200 mL/unit) units in 1998 to 22,000,000 RBC units in 2014. The percentage of human immunodeficiency virus (HIV) transfusion-transmitted infections in newly diagnosed HIV/AIDS has reduced from 29.6% in 2005 to less than 0.15% in 2013. The use of component therapy has increased from 18% in 1989 to 99% in 2014.
  
  
  
  Involvement of the government through enforcement of new statutes and regulations helped improve blood safety and clinical transfusion practice.
authors.affiliation: The Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China.
authors.forename: Ya
authors.initials: Y
authors.lastname: Wang
authors.affiliation: The Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China.|Bloodworks Northwest, Seattle, Washington.
authors.forename: Yanyun
authors.initials: Y
authors.lastname: Wu
authors.affiliation: The Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Chen
authors.affiliation: The Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China.
authors.forename: Changqing
authors.initials: C
authors.lastname: Li
authors.affiliation: The Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China.
authors.forename: Li
authors.initials: L
authors.lastname: Lu
authors.affiliation: Bloodworks Northwest, Seattle, Washington.
authors.forename: James P
authors.initials: JP
authors.lastname: AuBuchon
authors.affiliation: The Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Liu
mesh_terms: D001782:Blood Donors; D058731:Blood Safety; D002681:China; D015658:HIV Infections / Q000635:transmission; D006801:Humans