title: [Prevention of the invasion of malignant cells of gynecologic tumors during surgery].
abstract: OBJECTIVE
  In experiments performed on Vistar rats with Walker tumors, F. Luksch observed transfer of malignant cells during different manipulations into the blood circulation of the animals. During gynecologic surgery of a choriocarcinoma and of an ovarian carcinoma Luksch and Cernoch prooved trace of malignant cells within the blood circulation related to the manipulation of tumors during surgery. Therefore, as prevention of the metastazing of tumor cells, they proposed to ligate ampular portions of oviducts and hypogastric vessels as the first step of the radical surgeries.
  
  
  METHODS
  Our observation is based on radical surgeries of 42 patients with cervical uterine carcinomas at the stage II.a (T2, N0, M0). In the first group 13 cases the ligature of oviducts and hypogastric vessels was performed at the start of the surgery. In the second group of 29 patients were operated without ligatures.
  
  
  RESULTS
  After five years in the group of 13 ligated patients 10 patients (77%) survived. In the group of 29 unligated patients only 7 (24%) were alive. The results proove substantial differences.
  
  
  CONCLUSIONS
  Although the members are small, there is doubt, that the ligation of oviducts and hypogastric vessels prior radical surgeries in patients affected by malignant gynecologic tumors substantially reduces metastazing of malignant cells nad improve the five years survival of surgically treated patients with gynecologic malignant tumors.
authors.forename: J
authors.initials: J
authors.lastname: Kobilková
authors.forename: J E
authors.initials: JE
authors.lastname: Jirásek
authors.forename: J
authors.initials: J
authors.lastname: Jedlicková
authors.forename: O
authors.initials: O
authors.lastname: Benešová
authors.forename: J
authors.initials: J
authors.lastname: Mašata
mesh_terms: D000818:Animals; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D008026:Ligation; D009361:Neoplasm Invasiveness / Q000517:prevention & control; D009362:Neoplasm Metastasis / Q000517:prevention & control*; D009367:Neoplasm Staging; D009360:Neoplastic Cells, Circulating; D010051:Ovarian Neoplasms / Q000473:pathology; D011183:Postoperative Complications / Q000517:prevention & control; D051381:Rats; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*