title: A Switchable Gold Catalyst by Encapsulation in a Self-Assembled Cage.
abstract: Dinuclear gold complexes have the ability to interact with one or more substrates in a dual-activation mode, leading to different reactivity and selectivity than their mononuclear relatives. In this contribution, this difference was used to control the catalytic properties of a gold-based catalytic system by site-isolation of mononuclear gold complexes by selective encapsulation. The typical dual-activation mode is prohibited by this catalyst encapsulation, leading to typical behavior as a result of mononuclear activation. This strategy can be used as a switch (on/off) for a catalytic reaction and also permits reversible control over the product distribution during the course of a reaction.
authors.affiliation: Homogeneous, Bioinspired and Supramolecular Catalysis, van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, the Netherlands.
authors.forename: Anne C H
authors.initials: AC
authors.lastname: Jans
authors.affiliation: School of Chemistry, University of St Andrews, St Andrews, KY16 9ST, UK.
authors.forename: Adrián
authors.initials: A
authors.lastname: Gómez-Suárez
authors.affiliation: Department of Inorganic and Physical Chemistry, Ghent University, Krijgslaan 281 - S3, 9000, Gent, Belgium.|Chemistry Department, College of Science, King Saud university PO Box 2455, Riyadh, 11451, Saudi Arabia.
authors.forename: Steven P
authors.initials: SP
authors.lastname: Nolan
authors.affiliation: Homogeneous, Bioinspired and Supramolecular Catalysis, van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, the Netherlands. j.n.h.reek@uva.nl.
authors.forename: Joost N H
authors.identifier: http://orcid.org/0000-0001-5024-508X
authors.initials: JN
authors.lastname: Reek
keywords: catalyst encapsulation; catalytic switch; dual catalysis; gold catalysis; supramolecular chemistry