title: The effects of povidone iodine (pH 4.2) on patients with adenoviral conjunctivitis.
abstract: OBJECTIVE
  To compare the efficacy of classical treatment and povidone-iodine treatment for adenoviral conjunctivitis.
  
  
  METHODS
  This retrospective study was conducted at the Centre of Marmara Eye Health, Sakarya, Turkey, between January 2011 and February 2014, and comprised adult patients suffering from adenoviral conjunctivitis. The participants were randomly divided into two groups. Group I was given povidone-iodine solution while Group II was given the classical treatment and was taken as control. Povidone-iodine treatment was administered as three drops three times per day. The classical treatment comprised three drops of trifluorothymidine three times per day. Treatment were continued for two weeks. The patients who had not recovered in this time frame were defined as 'late recovering' patients. SPSS 23 was used for data analysis.
  
  
  RESULTS
  Of the 112 participants, there were 56(50%) in each group. In Group I, 54(96.4%) patients recovered in two weeks, while 2(3.6%) took more time. In Group II, 33(58.9%) patients recovered in two weeks while 23(41.1%) took more time (p<0.001). Overall, 92(82.1%) patients had familial transmission-contamination.
  
  
  CONCLUSIONS
  A new treatment protocol of povidone-iodine was used safely in patients with adenoviral conjunctivitis. Familial transmission was found very important to adenoviral conjunctivitis infection.
authors.affiliation: Department of Medicine, Sakarya University Faculty of Medicine, Sakarya, Istanbul, Turkey.
authors.forename: Hayrullah
authors.initials: H
authors.lastname: Yazar
authors.affiliation: Special Marmara Eye Clinic Center, Sakarya, Istanbul, Turkey.
authors.forename: Abdulhekim
authors.initials: A
authors.lastname: Yarbag
authors.affiliation: Infectious Diseases and Clinical Microbiology, Bolu State Hospital, Bolu, Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Balci
authors.affiliation: Infectious Diseases and Clinical Microbiology, Nisa Hospital, Istanbul, Turkey.
authors.forename: Bahri
authors.initials: B
authors.lastname: Teker
authors.affiliation: Department of Pharmacology, Sakarya University Faculty of Medicine, Sakarya, Istanbul, Turkey.
authors.forename: Pelin
authors.initials: P
authors.lastname: Tanyeri
mesh_terms: D000258:Adenovirus Infections, Human / Q000188:drug therapy*; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use; D003236:Conjunctivitis, Viral / Q000188:drug therapy*; D006801:Humans; D011206:Povidone-Iodine / Q000627:therapeutic use*; D012189:Retrospective Studies; D013997:Time Factors; D014271:Trifluridine / Q000627:therapeutic use
chemical_list: D000891:Anti-Infective Agents, Local; D000998:Antiviral Agents; D011206:Povidone-Iodine; D014271:Trifluridine
keywords: Adenoviral conjunctivitis, Povidone-iodine, pH.