title: Eosinophilic Disorders of the Gastrointestinal Tract.
abstract: Eosinophilic gastrointestinal disorders represent a spectrum of disorders demonstrating gastrointestinal eosinophilia without any known cause for eosinophilia. Pathogenesis is not clearly established, but immune responses to dietary antigens are implicated. These disorders affect children and adults and are seen in association with allergic disorders. Eosinophilic esophagitis is diagnosed in the setting of mucosal eosinophilia on endoscopic biopsy and symptoms of esophageal dysfunction. Eosinophilic gastroenteritis is also diagnosed with endoscopic biopsies. Eosinophilic colitis commonly presents with lower gastrointestinal symptoms and is a diagnosis of exclusion.
authors.affiliation: Division of Gastroenterology, University of Missouri, 1 Hospital Drive, Columbia, MO 65212, USA. Electronic address: samiullah.nabi@gmail.com.
authors.lastname: Samiullah
authors.affiliation: Rutgers University, New Jersey Medical School, 150 Bergen Street, I-248, Newark, NJ 07103, USA.
authors.forename: Hadi
authors.initials: H
authors.lastname: Bhurgri
authors.affiliation: Division of Gastroenterology-Hepatology, University of Missouri, 1 Hospital Drive, Columbia, MO 65212, USA.
authors.forename: Umair
authors.initials: U
authors.lastname: Sohail
mesh_terms: D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000367:Age Factors; D003092:Colitis / Q000503:physiopathology / Q000628:therapy; D003937:Diagnosis, Differential; D004032:Diet; D016099:Endoscopy, Gastrointestinal; D004751:Enteritis / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D004802:Eosinophilia / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D057765:Eosinophilic Esophagitis / Q000503:physiopathology / Q000628:therapy; D005756:Gastritis / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D011320:Primary Health Care; D012008:Recurrence; D012720:Severity of Illness Index
chemical_list: D000305:Adrenal Cortex Hormones
keywords: Eosinophilic colitis; Eosinophilic esophagitis; Eosinophilic gastroenteritis; Eosinophilic gastrointestinal disorder (EGID)