title: [Changing trend of four immune-related diseases in Ningxia].
abstract: OBJECTIVE
  To understand the changing trends of immune-related diseases. Disease patterns from both pre-and post-immunization plan and after the immunization program were described, in order to provide evidence for the formulation and revision of immunization program and policy, in Ningxia Hui Autonomous Region.
  
  
  METHODS
  According to the time order descriptive method was used to analyze and compare the reported data on infectious diseases in Ningxia, between 1958 and 2014.
  
  
  RESULTS
  From 1958 to 2014, both incidence and mortality of infectious diseases and four diseases related to the immunization programs, in Ningxia appeared significantly low. Since the implementation of the immunization plan, the incidence and mortality of the 4 diseases declined significantly, with the average annual total incidence as 176.12/100 000 before the immunization plan dropped to 2.56/100 000 when the expanded immunization plan was put into practice. The incidence also showed a downward trend. Among diseases that under the immunization program, the incidence of measles appeared the highest, followed by pertussis. However, none of the case on diphtheria or polio appeared which was caused by the wild strains, in 1983 and 1994.
  
  
  CONCLUSIONS
  After the implementation of the immunization plan, the immune-related diseases seemed to have been under well controlled. and with remarkable social benefit. Immunization programs appeared the most effective measures to control and eliminate the acute infectious diseases in the region.
authors.affiliation: Ningxia Medical Universicity, Ningxia 750004, China.
authors.forename: H
authors.initials: H
authors.lastname: Lin
authors.affiliation: Integrated Business Section, Ningxia Centers for Disease Control and Prevention, Ningxia 750004, China.
authors.forename: J
authors.initials: J
authors.lastname: Yang
authors.affiliation: Health and Family Planning Commission of Ningxia, Ningxia 750004, China.
authors.forename: T X
authors.initials: TX
authors.lastname: Liu
mesh_terms: D002681:China / Q000453:epidemiology; D003140:Communicable Disease Control / Q000639:trends*; D003141:Communicable Diseases / Q000453:epidemiology; D006801:Humans; D007114:Immunization / Q000706:statistics & numerical data*; D017589:Immunization Programs; D015994:Incidence; D008457:Measles / Q000453:epidemiology / Q000517:prevention & control; D009026:Mortality / Q000639:trends*; D011051:Poliomyelitis / Q000209:etiology / Q000517:prevention & control; D012107:Research Design; D014611:Vaccination / Q000706:statistics & numerical data*; D014917:Whooping Cough / Q000453:epidemiology / Q000517:prevention & control