title: Ultrasonic assisted synergetic green synthesis of polycyclic imidazo(thiazolo)pyrimidines by using Fe3O4@clay core-shell.
abstract: A practical and green approach for the ultrasound-enhanced one-pot multicomponent synthesis of tetraheterocyclic imidazo(thiazolo)pyrimidines is described via the condensation of an 2-aminobenzimidazole or 2-aminobenzothiazole, dimedone and various aldehydes in the presence of Fe3O4@clay as an environmentally benign and reusable core/shell nanocomposite catalyst in relatively quantitative yields. This novel eco-friendly protocol includes several advantages such as avoiding hazardous solvents, reusability of the catalyst, easy work-up, short reaction times, room temperature and mild reaction conditions. Furthermore, ultrasonic irradiation and synergistic catalyst showed considerable superiority vs. traditional heating or stirring conditions.
authors.affiliation: Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran. Electronic address: maleki@iust.ac.ir.
authors.forename: Ali
authors.initials: A
authors.lastname: Maleki
authors.affiliation: Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran.
authors.forename: Morteza
authors.initials: M
authors.lastname: Aghaei
keywords: Fe(3)O(4)@clay core/shell nanocomposite; Green chemistry; Heterogeneous nanocatalyst; Imidazopyrimidines; Ultrasonic irradiation