title: An autocatalytic DNA machine with autonomous target recycling and cascade circular exponential amplification for one-pot, isothermal and ultrasensitive nucleic acid detection.
abstract: An autonomous target recycling and cascade circular exponential amplification strategy was proposed to construct an autocatalytic DNA machine, which afforded one-pot, isothermal and ultrasensitive detection of nucleic acids. A low detection limit of 0.61 fM toward the target DNA with an excellent selectivity could be obtained.
authors.affiliation: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Road, Qingdao 266042, China. sliu@qust.edu.cn.
authors.forename: Xinya
authors.initials: X
authors.lastname: Sun
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Mingsha
authors.initials: M
authors.lastname: Zhao
authors.forename: Changzhi
authors.initials: C
authors.lastname: Zhao
authors.forename: Shufeng
authors.initials: S
authors.lastname: Liu
mesh_terms: D015374:Biosensing Techniques; D002384:Catalysis; D004279:DNA, Viral / Q000097:blood / Q000378:metabolism; D006515:Hepatitis B virus / Q000235:genetics; D006801:Humans; D057230:Limit of Detection; D021141:Nucleic Acid Amplification Techniques; D009696:Nucleic Acids / Q000032:analysis* / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D013696:Temperature
chemical_list: D004279:DNA, Viral; D009696:Nucleic Acids