title: [Update to the recommendations for management of melanoma stages I to III].
abstract: As knowledge continues to develop, regular updates are necessary concerning recommendations for practice. The recommendations for the management of melanoma stages I to III were drawn up in 2005. At the request of the Société Française de Dermatologie, they have now been updated using the methodology for recommendations proposed by the Haute Autorité de Santé. In practice, the principal recommendations are as follows: for staging, it is recommended that the 7th edition of AJCC be used. The maximum excision margins have been reduced to 2cm. Regarding adjuvant therapy, the place of interferon has been reduced and no validated emerging medication has yet been identified. Radiotherapy may be considered for patients in stage III at high risk of relapse. The sentinel lymph node technique remains an option. Initial examination includes routine ultrasound as of stage II, with other examinations being optional in stages IIC and III. A shorter strict follow-up period (3years) is recommended for patients, but with greater emphasis on imaging.
authors.affiliation: Département de dermatologie, hôpital Saint-Éloi, CHU de Montpellier, 34295 Montpellier cedex 5, France. Electronic address: b-guillot@chu-montpellier.fr.
authors.forename: B
authors.initials: B
authors.lastname: Guillot
authors.affiliation: Service de dermatologie, hôpital du Bocage sud, CHU de Dijon, BP 1542, 21079 Dijon cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Dalac
authors.affiliation: Laboratoire de biochimie, institut de biologie, 9, quai Moncousu, 44093 Nantes cedex, France.
authors.forename: M G
authors.initials: MG
authors.lastname: Denis
authors.affiliation: Service de dermatologie, CHU de Rennes, Rennes, France.
authors.forename: A
authors.initials: A
authors.lastname: Dupuy
authors.affiliation: Service d'anatomie pathologique, CHU Ambroise-Paré-Boulogne, 92104 Boulogne cedex, France.
authors.forename: J-F
authors.initials: JF
authors.lastname: Emile
authors.affiliation: Centre anticancéreux Léon-Bérard, 28, rue Laennec, 69008 Lyon, France.
authors.forename: A
authors.initials: A
authors.lastname: De La Fouchardière
authors.affiliation: Service de médecine nucléire Sud et Pellegrin, CHU de Bordeaux, Bordeaux, France.
authors.forename: E
authors.initials: E
authors.lastname: Hindie
authors.affiliation: Service de médecine, centre hospitalier de Pau, 64000 Pau, France.
authors.forename: T
authors.initials: T
authors.lastname: Jouary
authors.affiliation: Service d'imagerie médicale, institut Gustave-Roussy, 94800 Villejuif, France.
authors.forename: N
authors.initials: N
authors.lastname: Lassau
authors.affiliation: Centre Oscar-Lambret, 3, rue Fréderic-Combemale, 59000 Lille, France.
authors.forename: X
authors.initials: X
authors.lastname: Mirabel
authors.affiliation: Institut Curie, 26, rue d'Ulm, 75005 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Piperno Neumann
authors.affiliation: 1, avenue du 6-Juin, 14000 Caen, France.
authors.forename: S
authors.initials: S
authors.lastname: De Raucourt
authors.affiliation: Université catholique de Louvain, 10, avenue Hippocrate, 1200 Bruxelles, Belgique.
authors.forename: R
authors.initials: R
authors.lastname: Vanwijck
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D017024:Chemotherapy, Adjuvant; D003952:Diagnostic Imaging; D005817:Genetic Counseling; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D000072662:Margins of Excision; D008545:Melanoma / Q000473:pathology* / Q000628:therapy*; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012878:Skin Neoplasms / Q000473:pathology* / Q000628:therapy*
chemical_list: D014408:Biomarkers, Tumor
keywords: Classification; Management; Melanoma; Mélanome; Prise en charge; Recommandations; Recommendations; Staging