title: Correlation of bladder wall thickness and treatment success in types of urinary incontinence.
abstract: OBJECTIVE
  The aim of the study was to investigate the correlation between mean bladder wall thickness (BWT) and treatment success in patients diagnosed with urinary incontinence, based on urodynamic test results.
  
  
  METHODS
  In this prospective study, patient urinary incontinence type was identified using urodynamic tests. Patients (N = 125) were categorized into three groups: urodynamic stress incontinence (SUI), detrusor over-activity (DO) and mixed urinary incontinence. Measurements from the bladder dome, anterior wall and trigone were averaged to calculate BWT. Student's t test and Mann-Whitney U test were used to compare pre-treatment BWT. Receiver operating characteristic (ROC) curve analysis was used to determine optimal cut-off values for BWT to predict treatment success.
  
  
  RESULTS
  Mean pre-treatment BWT significantly differed between success and non-success groups for each urinary incontinence type (p value for the SUI, DO and MUI groups was 0.043, 0.001 and 0.002 respectively). Using ROC curves to anticipate the treatment success, a threshold was calculated for mean pre-treatment BWT; 5.05 mm for SUI (sensitivity 74 %, specificity 66 %, positive predictive value [PPV] 85 %, negative predictive value [NPV] 50 %), 4.98 mm for DO (sensitivity 73 %, specificity 92 %, PPV 95 %, NPV 63 %) and 5.31 mm for mixed type (sensitivity 88 %, specificity 73 %, PPV 79 %, NPV 85 %).
  
  
  CONCLUSIONS
  The study results suggest a significant relationship between the pre-treatment BWT and the success of urinary incontinence treatment. The mean BWT may be used as a benchmark in assessing the responsiveness to treatment of urinary incontinence types.
authors.affiliation: Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Woman's Health Research and Education Hospital, Ankara, Turkey. burakakselim@hotmail.com.
authors.forename: Burak
authors.initials: B
authors.lastname: Akselim
authors.affiliation: Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Woman's Health Research and Education Hospital, Ankara, Turkey.
authors.forename: Melike
authors.initials: M
authors.lastname: Doğanay
authors.affiliation: Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Woman's Health Research and Education Hospital, Ankara, Turkey.
authors.forename: Nilay
authors.initials: N
authors.lastname: Özcan
authors.affiliation: Departments of Physical and Rehabilitation Medicine, Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey.
authors.forename: Sinem
authors.initials: S
authors.lastname: Akselim
authors.affiliation: Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Woman's Health Research and Education Hospital, Ankara, Turkey.
authors.forename: Sabri
authors.initials: S
authors.lastname: Cavkaytar
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012372:ROC Curve; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods; D001743:Urinary Bladder / Q000000981:diagnostic imaging / Q000473:pathology*; D014549:Urinary Incontinence / Q000628:therapy*
keywords: Bladder wall thickness; Female urinary incontinence; Ultrasound