title: Predictive factors of failure and mortality after CT-Guided percutaneous drainage of infected pancreatic necrosis.
abstract: BACKGROUND
  The traditional approach to the drainage of infected pancreatic necrosis (IPN) is open necrosectomy. As an alternative to open necrosectomy, percutaneous drainage is the first-line treatment of IPN. This study is aimed to identify predictive factor of failure after CT-guided percutaneous catheter drainage (PCD) of IPN.
  
  
  METHODS
  Between June 1st 1988 and October 31th 2011, 26 patients with IPN were treated by PCD. The outcome measures were the failure of the PCD and/or death. A descriptive analysis was performed followed by a comparative analysis of alive versus deceased patients and success group versus failure group. Univariate and multivariate analysis were performed to determine predictive factors of failure after percutaneous drainage or death.
  
  
  RESULTS
  The failure and mortality rates were respectively 38% and 34%. The size of catheter inferior to 10 French was the only variable associated with the percutaneous drainage failure (OR=27, CI95% [2.5-284.6], p=0.006]. The collection number on CT scan was associated with mortality (OR=2.2, IC95% [1-5.1], p=0.050).
  
  
  CONCLUSIONS
  PCD with catheter size equal or greater than 10 French is efficient tool for the treatment of IPN. Collection number on CT scan is an independent predictive factor of mortality.
authors.forename: Wejih
authors.initials: W
authors.lastname: Dougaz
authors.forename: Ibtissem
authors.initials: I
authors.lastname: Bouasker
authors.forename: Samia
authors.initials: S
authors.lastname: Ben Osman
authors.forename: Ramzi
authors.initials: R
authors.lastname: Nouira
authors.forename: Chadli
authors.initials: C
authors.lastname: Dziri
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019283:Pancreatitis, Acute Necrotizing / Q000000981:diagnostic imaging / Q000401:mortality* / Q000628:therapy*; D015641:Radiography, Interventional; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed