title: A New Non-glucosidic Iridoid from the Roots of Strychnos nux-blanda.
abstract: Strychnuxin (1), a new non-glucosidic iridoid, together with four known compounds, IX (2), loganetin (3), loganin (4) and sweroside (5), were isolated from the roots of Strychnos nux-blanda. The structures of all isolated compounds (1-5) were elucidated through their physical properties and by the use of spectroscopic methods, as well as comparisons with the previous literature. To the best of our knowledge, this is the first isolation of compounds 1-5 from this plant. All isolated compounds were evaluated for their in vitro cytotoxicity against five human cancer cell lines.
authors.forename: Jirapast
authors.initials: J
authors.lastname: Sichaem
authors.forename: Suttira
authors.initials: S
authors.lastname: Khumkratok
authors.forename: Pongpun
authors.initials: P
authors.lastname: Siripong
authors.forename: Santi
authors.initials: S
authors.lastname: Tip-pyang
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D031451:Strychnos / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D039823:Iridoids