title: Higher classification sensitivity of short metagenomic reads with CLARK-S.
abstract: The growing number of metagenomic studies in medicine and environmental sciences is creating increasing demands on the computational infrastructure designed to analyze these very large datasets. Often, the construction of ultra-fast and precise taxonomic classifiers can compromise on their sensitivity (i.e. the number of reads correctly classified). Here we introduce CLARK-S, a new software tool that can classify short reads with high precision, high sensitivity and high speed.
  
  
  
  CLARK-S is freely available at http://clark.cs.ucr.edu/ CONTACT: stelo@cs.ucr.eduSupplementary information: Supplementary data are available at Bioinformatics online.
authors.affiliation: Department of Computer Science and Engineering, University of California, Riverside, CA 92521, USA.
authors.forename: Rachid
authors.initials: R
authors.lastname: Ounit
authors.affiliation: Department of Computer Science and Engineering, University of California, Riverside, CA 92521, USA.
authors.forename: Stefano
authors.initials: S
authors.lastname: Lonardi
mesh_terms: D000465:Algorithms; D017753:Ecosystem; D006801:Humans; D056186:Metagenomics; D012984:Software