title: The Association between Hidradenitis Suppurativa and Crohn's Disease: in Search of the Missing Pathogenic Link.
abstract: Hidradenitis suppurativa is a chronic, autoinflammatory skin disease. Shalom et al. demonstrate in a large cross-sectional study an association between Crohn's disease and hidradenitis suppurativa, but not with ulcerative colitis. This association supports the hypothesis that a similar pathogenic mechanism contributes to both diseases, providing new possibilities for functional studies and therapy development.
authors.affiliation: Department of Dermatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands. Electronic address: h.vanderzee@erasmusmc.nl.
authors.forename: Hessel H
authors.initials: HH
authors.lastname: van der Zee
authors.affiliation: Department of Dermatology, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Barbara
authors.initials: B
authors.lastname: Horvath
authors.affiliation: Department of Dermatology, Zealand University Hospital, Roskilde; Health Sciences Faculty, University of Copenhagen, Denmark.
authors.forename: Gregor B E
authors.initials: GBE
authors.lastname: Jemec
authors.affiliation: Department of Dermatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands; Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
authors.forename: Errol P
authors.initials: EP
authors.lastname: Prens
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D015897:Comorbidity; D003424:Crohn Disease / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D004359:Drug Therapy, Combination; D005260:Female; D017497:Hidradenitis Suppurativa / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents