title: Iron deficiency in patients with heart failure.
abstract: Iron deficiency (ID) is a commonly present co-morbidity in patients with heart failure (HF). In iron deficient but otherwise healthy individuals, correction of ID restores exercise capacity and endurance regardless of the presence of anaemia. Recently, iron replacement in patients with HF with reduced ejection fraction has been shown to improve symptoms and exercise capacity. This article reviews the clinical relevance of ID in HF and evidence for iron replacement.
authors.affiliation: Department of Medicine and National Institute for Health Innovation, University of Auckland, and Greenlane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.
authors.forename: Sarah
authors.initials: S
authors.lastname: Fitzsimons
authors.affiliation: Department of Medicine and National Institute for Health Innovation, University of Auckland, and Greenlane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.
authors.forename: Robert Neil
authors.initials: RN
authors.lastname: Doughty
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000209:etiology*; D005293:Ferritins / Q000097:blood*; D006333:Heart Failure / Q000097:blood / Q000150:complications*; D006801:Humans; D007501:Iron / Q000097:blood*
chemical_list: D005293:Ferritins; D007501:Iron
keywords: Heart failure; Iron deficiency