title: Sleep: Switching Off the Off-Switch.
abstract: What are the synaptic drives controlling the sleep-wake circuitry in the mammalian brain? In a new study it was found that GABAergic cells in posterior lateral hypothalamus inhibit sleep-promoting anterior hypothalamic cells to cause waking, whereas their inhibition augments sleep.
authors.affiliation: Department of Fundamental Neurosciences, University of Lausanne, Rue du Bugnon 9, CH-1005 Lausanne, Switzerland. Electronic address: anita.luthi@unil.ch.
authors.forename: Anita
authors.initials: A
authors.lastname: Lüthi
mesh_terms: D000818:Animals; D001921:Brain; D007031:Hypothalamus; D012890:Sleep; D014851:Wakefulness