title: Phytochemicals in Capsicum oleoresin from different varieties of hot chilli peppers with their antidiabetic and antioxidant activities due to some phenolic compounds.
abstract: Due to its wide use in nutritional therapy, a capsicum oleoresin extraction from hot chilli pepper was optimized using ultrasound assisted extraction. Under optimal conditions, a 0.1g sample in 10mL of a 20% water in methanol solution was extracted at 50°C for 20min to remove phytochemicals consisting of oleoresin, phenolics, carotenoids, flavonoids, capsaicinoids (pungency level), reducing sugars. Antioxidant and antidiabetic activities of the crude extracts from 14 chilli pepper varieties were examined. The antioxidant and antidiabetic activities of some phenolic compounds were also tested individually. The results showed that these chilli pepper samples are a rich source of phytochemicals with antioxidant and antidiabetic activities. High antioxidant activity of the extracts was evaluated using the 2,2-diphenyl-1-picrylhydrazyl, N,N-dimethyl-p-phenylenediamine dihydrochloride, 2,2'-azino-bis(3-ethylbenzothiazolin-6-sulfonic acid) and ferric ion reducing antioxidant power assays. The crude extracts had a lower level of sugars induced by the inhibitory effect of α-amylase activity. Thus, their enzymatic inhibitory effect might have resulted from a synergism among the phytochemicals concerned. Therefore, a diet with this type of food may have beneficial health effects.
authors.affiliation: Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
authors.forename: Phitchan
authors.initials: P
authors.lastname: Sricharoen
authors.affiliation: Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
authors.forename: Nattida
authors.initials: N
authors.lastname: Lamaiphan
authors.affiliation: Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
authors.forename: Pongpisoot
authors.initials: P
authors.lastname: Patthawaro
authors.affiliation: Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
authors.forename: Nunticha
authors.initials: N
authors.lastname: Limchoowong
authors.affiliation: Department of Plant Science and Agricultural Resources, Faculty of Agriculture, Khon Kaen University, Khon Kaen 40002, Thailand.
authors.forename: Suchila
authors.initials: S
authors.lastname: Techawongstien
authors.affiliation: Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: sakcha2@kku.ac.th.
authors.forename: Saksit
authors.initials: S
authors.lastname: Chanthai
mesh_terms: D000975:Antioxidants / Q000032:analysis / Q000494:pharmacology; D002212:Capsicum / Q000737:chemistry*; D002338:Carotenoids / Q000032:analysis; D005419:Flavonoids / Q000032:analysis; D007004:Hypoglycemic Agents / Q000032:analysis / Q000494:pharmacology; D010636:Phenols / Q000032:analysis* / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry*; D013045:Species Specificity; D000516:alpha-Amylases / Q000037:antagonists & inhibitors
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D007004:Hypoglycemic Agents; D010636:Phenols; D010936:Plant Extracts; C018620:oleoresins; D002338:Carotenoids; D000516:alpha-Amylases
keywords: Antidiabetic; Antioxidants; Chilli pepper; Phenolics; Phytochemicals; Ultrasound assisted extraction