title: An International Asset Map of Clinicians, Educators, and Researchers Pursuing Better Medicine Use in Children: Initial Findings.
abstract: The world's 1.89 billion children (age 0-14) too frequently receive treatments that have not been validated through clinical pharmacology research, especially in low- and middle-income countries. Initial findings from an international asset map of professionals and clinician scientists available to address the needs for education, research, and treatment support suggest a critical shortage of clinical pharmacologists, clinical pharmacists, and other professionals with advanced training in the evaluation of therapies for childhood conditions and illnesses. A total of 497 individuals responded to a survey conducted between May 2015 and February 2016. An alarming signal is apparent showing that, while the overall resource pool is unquestionably limited, 87% of relevant qualified personnel are located in high-income countries. The data suggest an urgent need for targeted training in pediatric clinical pharmacology, with particular focus on the needs in Africa, Latin America, and most of Asia.
authors.affiliation: Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.|Child & Family Research Institute, BC Children's Hospital, Vancouver, British Columbia, Canada.
authors.forename: S M
authors.initials: SM
authors.lastname: MacLeod
authors.affiliation: Department of Paediatrics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.|Robarts Research Institute, London, Ontario, Canada.
authors.forename: Mje
authors.initials: M
authors.lastname: Greff
authors.affiliation: Faculty of Science, School of Pharmacy, University of Waterloo, Kitchener, Ontario, Canada.
authors.forename: D C
authors.initials: DC
authors.lastname: Knoppert
authors.affiliation: Division of Clinical Pharmacology & Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.|Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Ito
authors.affiliation: Department of Paediatrics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.|Robarts Research Institute, London, Ontario, Canada.|Department of Physiology & Pharmacology, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.|Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.|CIHR-GSK Chair in Paediatric Clinical Pharmacology, Children's Hospital of Western Ontario, London, Ontario, Canada.
authors.forename: M J
authors.initials: MJ
authors.lastname: Rieder
mesh_terms: D000293:Adolescent; D035843:Biomedical Research / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D019049:Developed Countries / Q000706:statistics & numerical data; D003906:Developing Countries / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007391:International Cooperation; D010372:Pediatrics / Q000706:statistics & numerical data*; D012108:Research Personnel / Q000600:supply & distribution*