title: Ferrocene-Boronic Acid-Fructose Binding Based on Dual-Plate Generator-Collector Voltammetry and Square-Wave Voltammetry.
abstract: The interaction of ferrocene-boronic acid with fructose is investigated in aqueous 0.1 m phosphate buffer at pH 7, 8 and 9. Two voltammetric methods, based on 1) a dual-plate generator-collector micro-trench electrode (steady state) and 2) a square-wave voltammetry (transient) method, are applied and compared in terms of mechanistic resolution. A combination of experimental data is employed to obtain new insights into the binding rates and the cumulative binding constants for both the reduced ferrocene-boronic acid (pH dependent and weakly binding) and for the oxidised ferrocene-boronic acid (pH independent and strongly binding).
authors.affiliation: Department of Chemistry, University of Bath Claverton Down, Bath BA2 7AY (UK) E-mail: f.marken@bath.ac.uk.
authors.forename: Meng
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Chemistry, University of Bath Claverton Down, Bath BA2 7AY (UK) E-mail: f.marken@bath.ac.uk.
authors.forename: Su-Ying
authors.initials: SY
authors.lastname: Xu
authors.affiliation: Department of Chemistry, University of Bath Claverton Down, Bath BA2 7AY (UK) E-mail: f.marken@bath.ac.uk.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Gross
authors.affiliation: Department of Electronic and Electrical Engineering, University of Bath Claverton Down, Bath BA2 7AY (UK).
authors.forename: Jules L
authors.initials: JL
authors.lastname: Hammond
authors.affiliation: Department of Electronic and Electrical Engineering, University of Bath Claverton Down, Bath BA2 7AY (UK).
authors.forename: Pedro
authors.initials: P
authors.lastname: Estrela
authors.affiliation: Department of Chemistry, University of Bath Claverton Down, Bath BA2 7AY (UK) E-mail: f.marken@bath.ac.uk.
authors.forename: James
authors.initials: J
authors.lastname: Weber
authors.affiliation: CEITEC, Masaryk University Kamenice 5, CS-62500 Brno (Czech Republic).
authors.forename: Karel
authors.initials: K
authors.lastname: Lacina
authors.affiliation: Department of Chemistry, University of Bath Claverton Down, Bath BA2 7AY (UK) E-mail: f.marken@bath.ac.uk.
authors.forename: Tony D
authors.initials: TD
authors.lastname: James
authors.affiliation: Department of Chemistry, University of Bath Claverton Down, Bath BA2 7AY (UK) E-mail: f.marken@bath.ac.uk.
authors.forename: Frank
authors.initials: F
authors.lastname: Marken
keywords: boronic acids; electroanalysis; ferrocene; saccharides; voltammetry