title: Novel technique of endoscopic full-thickness resection for superficial nonampullary duodenal neoplasms to avoid intraperitoneal tumor dissemination.
abstract: Recently, laparoscopic and/or endoscopic full-thickness resection (FTR) has been reported to be a useful technique for the treatment of superficial duodenal neoplasms (SDNs). In the current study, we evaluated clinical outcomes in 5 consecutive patients who underwent resection of nonampullary SDNs using laparoscopy-assisted endoscopic full-thickness resection with ligation Device (LAEFTR-L), which is an alternative FTR method developed to avoid peritoneal dissemination. Using a snare technique with a ligation band, the duodenal lesions were easily resected. The provisional and additional sutures for the resected site prevented delayed perforation and bleeding and they also protected the abdominal cavity from direct exposure to malignant cells. Complete resection could be achieved and FTR was histologically confirmed in all cases. The mean operation time was 173 minutes (range 138 - 217 minutes). Mean diameter of the resected specimen was 24 mm (range 18 - 32 mm). No adverse events (AEs) were observed. LAEFTR-L, which can achieve complete resection of nonampullary SDNs without severe AEs and peritoneal dissemination, could be a useful technique for the treatment of such lesions.
authors.affiliation: Department of Gastroenterology, NTT Medical Center Tokyo, Tokyo, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Ohata
authors.affiliation: Department of Gastroenterology, NTT Medical Center Tokyo, Tokyo, Japan.
authors.forename: Kouichi
authors.initials: K
authors.lastname: Nonaka
authors.affiliation: Department of Gastroenterology, NTT Medical Center Tokyo, Tokyo, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Sakai
authors.affiliation: Department of Gastroenterology, NTT Medical Center Tokyo, Tokyo, Japan.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Minato
authors.affiliation: Department of Surgery, NTT Medical Center Tokyo, Tokyo, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Satodate
authors.affiliation: Department of Surgery, NTT Medical Center Tokyo, Tokyo, Japan.
authors.forename: Kazuteru
authors.initials: K
authors.lastname: Watanabe
authors.affiliation: Department of Gastroenterology, NTT Medical Center Tokyo, Tokyo, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Matsuhashi