title: Antioxidant Activities of Peptoid-Grafted Chitosan Films.
abstract: The aim of this study was to investigate the possibility of immobilizing peptoid on chitosan film in order to generate new active material. Chitosan films have been grafted for the first time with short-length peptoid oligomers displaying antioxidant activities. The antioxidant activity of the selected peptoids was initially investigated with the DPPH assay and hydroxyl radical procedure. The metal chelating capacity of peptoids was also evaluated prior to their covalent attachment to chitosan. The benefit of chitosan functionalization with respect to its intrinsic antioxidant properties was finally evaluated in the present study. Interestingly, an increase of up to 90 % of the antioxidant activity of chitosan was observed.
authors.affiliation: Clermont Université, Université Blaise Pascal, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000, Clermont-Ferrand, France.|CNRS, UMR 6296, ICCF, F-63178, Aubière Cedex, France.|Université Clermont Auvergne, Université Blaise Pascal, Institut Pascal, BP 10448, F-63000, Clermont-Ferrand, France.|CNRS, UMR 6602, Institut Pascal, F-63178, Aubière, France.
authors.forename: P-H
authors.initials: PH
authors.lastname: Elchinger
authors.affiliation: Université Clermont Auvergne, Université Blaise Pascal, Institut Pascal, BP 10448, F-63000, Clermont-Ferrand, France. cedric.delattre@univ-bpclermont.fr.|CNRS, UMR 6602, Institut Pascal, F-63178, Aubière, France. cedric.delattre@univ-bpclermont.fr.
authors.forename: C
authors.initials: C
authors.lastname: Delattre
authors.affiliation: Clermont Université, Université Blaise Pascal, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000, Clermont-Ferrand, France.|CNRS, UMR 6296, ICCF, F-63178, Aubière Cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Faure
authors.affiliation: Clermont Université, Université Blaise Pascal, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000, Clermont-Ferrand, France.|CNRS, UMR 6296, ICCF, F-63178, Aubière Cedex, France.
authors.forename: O
authors.initials: O
authors.lastname: Roy
authors.affiliation: BioFilm Control, rue Emile Duclaux, Biopôle Clermont Limagne, 63360, Saint-Beauzire, France.
authors.forename: S
authors.initials: S
authors.lastname: Badel
authors.affiliation: BioFilm Control, rue Emile Duclaux, Biopôle Clermont Limagne, 63360, Saint-Beauzire, France.
authors.forename: T
authors.initials: T
authors.lastname: Bernardi
authors.affiliation: Université Clermont Auvergne, Université Blaise Pascal, Institut Pascal, BP 10448, F-63000, Clermont-Ferrand, France.|CNRS, UMR 6602, Institut Pascal, F-63178, Aubière, France.
authors.forename: P
authors.initials: P
authors.lastname: Michaud
authors.affiliation: Clermont Université, Université Blaise Pascal, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000, Clermont-Ferrand, France.|CNRS, UMR 6296, ICCF, F-63178, Aubière Cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Taillefumier
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000737:chemistry; D048271:Chitosan / Q000737:chemistry / Q000494:pharmacology; D018857:Food Packaging; D006801:Humans; D017665:Hydroxyl Radical / Q000737:chemistry; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000187:drug effects*; D034444:Peptoids / Q000737:chemistry* / Q000494:pharmacology; D010851:Picrates / Q000737:chemistry
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D034444:Peptoids; D010851:Picrates; D017665:Hydroxyl Radical; D048271:Chitosan; C004931:1,1-diphenyl-2-picrylhydrazyl
keywords: Antioxidant; Biosourced material; Chitosan film; Grafting; Peptoid; Polysaccharide