title: Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter.
abstract: OBJECTIVE
  The aim of this study was to evaluate the relationship between tumor size and grade with visceral adipose index (VAI) levels in patients with renal cell carcinoma.
  
  
  METHODS
  We retrospectively reviewed the records of 310 consecutive patients with RCC who underwent radical nephrectomy at our institution between January 2007 and May 2014. VAI was calculates for males and females seperately as this formula like previous study. The relationship between tumor size and nuclear grade with VAI levels were evaluated statisticaly. Analyses were completed using Chi-square tests and Logistic regression analysis.
  
  
  RESULTS
  Among the 310 total patients analyzed in our study, there were 176 males (56.8%) and 134 females (43.2%). VAI levels were statistically higher in men and women with high tumor size (p < 0,001). VAI levels were statistically higher in men and women with high fuhrman grade (p < 0,001).
  
  
  CONCLUSIONS
  The components of VAI may have effect on tumor carcinogenesis in similar pathways. In our study patients with high VAI levels were found to have statistically significant higher nuclear grade and tumor size. VAI can be a useful index for the evaluation and calculation of renal cell cancer aggressiviness. Further studies with more patients are needed to confirm our study.
authors.affiliation: Department of Urology, Okmeydani, Training and Research Hospital, Istanbul, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Otunctemur
authors.affiliation: Department of Urology, Okmeydani, Training and Research Hospital, Istanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Dursun
authors.affiliation: Department of Urology, Ataturk Training and Research Hospital, Izmir, Turkey.
authors.forename: Kutan
authors.initials: K
authors.lastname: Ozer
authors.affiliation: Department of Urology, Ataturk Training and Research Hospital, Izmir, Turkey.
authors.forename: Ozan
authors.initials: O
authors.lastname: Horsanali
authors.affiliation: Department of Urology, Okmeydani, Training and Research Hospital, Istanbul, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Ozbek
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000473:pathology*; D007680:Kidney Neoplasms / Q000473:pathology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012737:Sex Factors; D047368:Tumor Burden; D055105:Waist Circumference
keywords: Body Mass Index; Carcinoma, Renal Cell; Visceral Pain