title: Long-term evaluation of teeth and implants during the periodic maintenance in patients with viral liver disease.
abstract: OBJECTIVE
  This study was designed to investigate the maintenance of teeth and implants in patients with viral liver disease.
  
  
  METHODS
  316 patients without any significant systemic disease were selected as a control group. Liver disease group was consisted of 230 patients. Necessary data were collected using clinical records and panoramic radiographs. Then, the patients were subdivided into 2 groups based on the type of active dental therapy received before maintenance period (Pre-Tx). Analysis for finding statistically significant difference was performed based on the need for re-treatment of active dental therapy (Re-Tx) and change in the number of teeth (N-teeth) and implants (N-implants).
  
  
  RESULTS
  Comparing to control group, the patients with liver disease showed higher value on N-teeth, N-implants, and Re-Tx. Statistically significant differences were found on N-teeth (P=.000) and Re-Tx (P=.000) in patients with non-surgical Pre-Tx. Analysis based on severity of liver disease showed that N-teeth and Re-Tx were directly related to severity of liver disease regardless of received type of Pre-Tx. Significant differences were found on N-teeth (P=.003) and Re-Tx (P=.044) in patients with non-surgical Pre-Tx.
  
  
  CONCLUSIONS
  In this study, it was concluded that liver disease might influence the loss of teeth and cause the relapse of dental disease during maintenance period in patients. A significant positive relationship between tooth and implant loss and severity of liver disease seems to exist.
authors.affiliation: Department of Periodontology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
authors.forename: Da-Le
authors.identifier: 0000-0003-4415-8689
authors.initials: DL
authors.lastname: Yoon
authors.affiliation: Department of Periodontology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
authors.forename: Yong-Gun
authors.identifier: 0000-0002-2793-7667
authors.initials: YG
authors.lastname: Kim
authors.affiliation: Department of Prosthodontics, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
authors.forename: Jin-Hyun
authors.identifier: 0000-0002-2453-9372
authors.initials: JH
authors.lastname: Cho
authors.affiliation: College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Republic of Korea.
authors.forename: Sang-Kyu
authors.identifier: 0000-0001-5343-701X
authors.initials: SK
authors.lastname: Lee
authors.affiliation: Department of Periodontology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
authors.forename: Jae-Mok
authors.identifier: 0000-0002-0291-6114
authors.initials: JM
authors.lastname: Lee
keywords: Liver disease; Long-term care; Tooth loss