title: Gold-catalyzed Intermolecular Oxidations of 2-Ketonyl-1-ethynyl Benzenes with N-Hydoxyanilines to Yield 2-Aminoindenones via Gold Carbene Intermediates.
abstract: Gold-catalyzed oxidations of 2-ketonyl-1-ethynyl benzenes with N-hydroxyanilines yield 2-aminoindenone derivatives efficiently. Experimental data suggests that this process involves an α-oxo gold carbene intermediate, generated from the attack of N-hydroxyaniline on furylgold carbene intermediate, rather than the typical attack of oxidants on π-alkynes.
authors.affiliation: Department of Chemistry, National Tsing-Hua University, Hsinchu, 30013, Taiwan, ROC.
authors.forename: Bhanudas Dattatray
authors.initials: BD
authors.lastname: Mokar
authors.affiliation: Department of Chemistry, National Tsing-Hua University, Hsinchu, 30013, Taiwan, ROC.
authors.forename: Deepak B
authors.initials: DB
authors.lastname: Huple
authors.affiliation: Department of Chemistry, National Tsing-Hua University, Hsinchu, 30013, Taiwan, ROC. rsliu@mx.nthu.edu.tw.
authors.forename: Rai-Shung
authors.initials: RS
authors.lastname: Liu
keywords: alkynes; carbenes; gold; heterocycles; oxidations