title: Tailoring particle translocation via dielectrophoresis in pore channels.
abstract: Understanding and controlling electrophoretic motions of nanoscopic objects in fluidic channels are a central challenge in developing nanopore technology for molecular analyses. Although progress has been made in slowing the translocation velocity to meet the requirement for electrical detections of analytes via picoampere current measurements, there exists no method useful for regulating particle flows in the transverse directions. Here, we report the use of dielectrophoresis to manipulate the single-particle passage through a solid-state pore. We created a trap field by applying AC voltage between electrodes embedded in a low-aspect-ratio micropore. We demonstrated a traffic control of particles to go through center or near side surface via the voltage frequency. We also found enhanced capture efficiency along with faster escaping speed of particles by virtue of the AC-mediated electroosmosis. This method is compatible with nanopore sensing and would be widely applied for reducing off-axis effects to achieve single-molecule identification.
authors.affiliation: The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.|Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Shoji
authors.initials: S
authors.lastname: Tanaka
authors.affiliation: The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
authors.forename: Makusu
authors.initials: M
authors.lastname: Tsutsui
authors.affiliation: School of Optical and Electronic Information, Huazhong University of Science and Technology, Luo Yu Road, Wuhan 430074, China.
authors.forename: Hu
authors.initials: H
authors.lastname: Theodore
authors.affiliation: School of Optical and Electronic Information, Huazhong University of Science and Technology, Luo Yu Road, Wuhan 430074, China.
authors.forename: He
authors.initials: H
authors.lastname: Yuhui
authors.affiliation: The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
authors.forename: Akihide
authors.initials: A
authors.lastname: Arima
authors.affiliation: Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Tsuji
authors.affiliation: Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Doi
authors.affiliation: Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Satoyuki
authors.initials: S
authors.lastname: Kawano
authors.affiliation: The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
authors.forename: Masateru
authors.initials: M
authors.lastname: Taniguchi
authors.affiliation: The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan.
authors.forename: Tomoji
authors.initials: T
authors.lastname: Kawai