title: Management of Breast Sarcoma.
abstract: Breast sarcomas are exceptionally rare mesenchymal neoplasms composed of many histologic subtypes. Therapy is guided by principles established in the management of extremity sarcomas. The anatomic site does influence treatment decisions, particularly the surgical management. Surgery should be undertaken with the aim of achieving a widely negative margin. Selected patients can be managed with breast-conserving surgery. Breast reconstruction is increasingly being undertaken for selected patients. Radiation therapy and chemotherapy are used selectively for large, high-grade sarcomas for which there is significant concern for local and distant recurrence.
authors.affiliation: Department of Surgery, Baylor College of Medicine, One Baylor Plaza, MS 390, Houston, TX 77030, USA. Electronic address: Cary.Hsu@bcm.edu.
authors.forename: Cary
authors.initials: C
authors.lastname: Hsu
authors.affiliation: Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
authors.forename: Susan A
authors.initials: SA
authors.lastname: McCloskey
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
authors.forename: Parvin F
authors.initials: PF
authors.lastname: Peddi
mesh_terms: D001943:Breast Neoplasms / Q000628:therapy*; D003131:Combined Modality Therapy; D019468:Disease Management; D005260:Female; D006801:Humans; D012509:Sarcoma / Q000628:therapy*
keywords: Breast; Chemotherapy; Multidisciplinary; Radiation; Sarcoma; Surgery