title: [A rare cause of ilio-femoral deep vein thrombosis in young adults: asymptomatic chronic inferior vena cava occlusion].
abstract: BACKGROUND
  Acute lower extremity deep venous thrombosis in young adults is usually related to thrombophilia, immobility, trauma, surgery or malignancy. Therapeutic options have recently included pharmacomechanical thrombus removal although there is no evidence of the indication or of the long-term benefit. Rarely unknown, asymptomatic chronic neonatal inferior vena cava occlusion could also lead to acute ilio-femoral thrombosis.
  
  
  OBJECTIVE
  The aim of the authors was to present the therapeutic possibilities in lower extremity deep venous thrombosis connected with chronic inferior vena cava occlusion.
  
  
  METHODS
  In a retrospective single center study data of 21 adults were analyzed.
  
  
  RESULTS
  In 4 of the 21 patients chronic inferior vena cava obstruction was identified as an underlying cause of the acute thrombosis. Pharmacomechanical lysis was not offered to them and anticoagulation therapy was introduced. After an average 27.5 ± 11 month follow-up all the patients were alive and no adverse event occurred.
  
  
  CONCLUSIONS
  In patients with acute lower extremity deep venous thrombosis and chronic inferior vena cava occlusion the indication of the endovenous pharmacomechanical lysis therapy is questionable. The authors suggest to consider computed tomography angiography or magnetic resonance angiography in addition to duplex sonography in patients with no obvious risk factors for lower extremity deep venous thrombosis to avoid unnecessary invasive treatment. Orv. Hetil., 2016, 157(34), 1361-1365.
authors.affiliation: Városmajori Szív- és Érgyógyászati Klinika, Érsebészeti Tanszék, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Városmajor utca 68., 1122.
authors.forename: Gerda Brigitta
authors.initials: GB
authors.lastname: Tóth
authors.affiliation: Városmajori Szív- és Érgyógyászati Klinika, Érsebészeti Tanszék, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Városmajor utca 68., 1122.
authors.forename: Csaba
authors.initials: C
authors.lastname: Csobay-Novák
authors.affiliation: Városmajori Szív- és Érgyógyászati Klinika, Érsebészeti Tanszék, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Városmajor utca 68., 1122.
authors.forename: Anikó
authors.initials: A
authors.lastname: Berencsi
authors.affiliation: Városmajori Szív- és Érgyógyászati Klinika, Érsebészeti Tanszék, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Városmajor utca 68., 1122.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Szeberin
mesh_terms: D000328:Adult; D000800:Angioplasty, Balloon / Q000379:methods; D005260:Female; D005268:Femoral Vein / Q000473:pathology*; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007084:Iliac Vein / Q000473:pathology*; D007866:Leg / Q000098:blood supply; D008297:Male; D015912:Thrombolytic Therapy / Q000379:methods; D014682:Vena Cava, Inferior / Q000473:pathology*; D020246:Venous Thrombosis / Q000175:diagnosis / Q000628:therapy*
chemical_list: D005343:Fibrinolytic Agents
keywords: deep vein thrombosis; endovascular technique; endovascularis technika; inferior vena cava; mélyvénás thrombosis; thrombolysis; vena cava inferior