title: Two cases of chronic immune sensorimotor polyradiculopathy: Expanding the spectrum of chronic immune polyradiculopathies.
abstract: Immune-mediated demyelinating radiculopathies restricted to proximal sensory or motor roots are uncommon.
  
  
  
  We report the clinical, electrophysiological, biochemical, and radiological features in 2 patients with chronic immune sensorimotor polyradiculopathy (CISMP).
  
  
  
  The patients presented with sensory ataxia, weakness of the lower limbs, and areflexia. Electrophysiological studies revealed involvement of proximal sensorimotor roots, as evidenced by changes in somatosensory evoked potentials, F-waves, and H-reflexes. In contrast, the distal nerve segments were normal. Magnetic resonance neurography findings of thickened and enhanced roots supported the electrophysiological findings. The response to immunosuppressive therapy was favorable in both patients.
  
  
  
  The findings from these 2 patients further expand the knowledge spectrum of immune polyradiculopathies. Muscle Nerve 55:135-137, 2017.
authors.affiliation: Department of Neurology, Grant Medical College and Sir J.J. Group of Hospitals, Mumbai, India.
authors.forename: Satish
authors.initials: S
authors.lastname: Khadilkar
authors.affiliation: Department of Neurology, Grant Medical College and Sir J.J. Group of Hospitals, Mumbai, India.
authors.forename: Bhagyadhan
authors.initials: B
authors.lastname: Patel
authors.affiliation: Department of Neurophysiology, Bombay Hospital, Mumbai, India.
authors.forename: Khushnuma A
authors.initials: KA
authors.lastname: Mansukhani
authors.affiliation: Department of Radiology, Bombay Hospital and Medical Research Centre, Mumbai, India.
authors.forename: Sunila
authors.initials: S
authors.lastname: Jaggi
mesh_terms: D000293:Adolescent; D000328:Adult; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D005260:Female; D006181:H-Reflex / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009431:Neural Conduction; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D013126:Spinal Nerve Roots / Q000000981:diagnostic imaging
keywords: chronic immune sensorimotor polyradiculopathy; demyelinating neuropathies; magnetic resonance neurography; nerve root thickening; somatosensory evoked potentials