title: Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles.
abstract: A convenient and efficient strategy has been devised to access 3-amino-2H-indazole derivatives in two steps from readily available starting materials. The conversion of 2-nitrobenzonitriles to substituted benzamidines followed by an organophosphorus-mediated reductive cyclization and a subsequent N-N bond formation afforded 3-amino-2H-indazoles in good to excellent yields.
authors.affiliation: Leibniz-Institut für Molekulare Pharmakologie (FMP), Campus Berlin-Buch, Robert-Roessle-Str. 10, 13125 Berlin, Germany. nazare@fmp-berlin.de.
authors.forename: Hassen
authors.initials: H
authors.lastname: Bel Abed
authors.forename: Jens
authors.initials: J
authors.lastname: Schoene
authors.forename: Mathias
authors.initials: M
authors.lastname: Christmann
authors.forename: Marc
authors.initials: M
authors.lastname: Nazaré