title: [TUBERCULOSIS GRANULOMA: THE CURRENT VIEW OF ITS IMMUNOGENESIS AND CELLULAR COMPOSITION].
abstract: The review presents the available basic scientific data characterizing the current views of the immunological homeostasis of intact lung tissue, the population and subpopulation composition of the cells forming a tuberculosis granuloma, as well as their phenotypic characteristics, the factors contributing to macrophageal transformation into epitheliod cells and Pirogov-Langhans giant cells, and the effect of mycobacterial antigens on this process.
mesh_terms: D015744:Giant Cells, Langhans / Q000276:immunology; D006801:Humans; D008168:Lung / Q000276:immunology* / Q000473:pathology; D009169:Mycobacterium tuberculosis / Q000276:immunology / Q000472:pathogenicity; D014375:Tuberculoma / Q000276:immunology / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000276:immunology / Q000473:pathology