title: [Research Progress on Inflammasome and Cancer-associated Thrombosis-Review].
abstract: Inflammasome is a complex of protein, which can recognize pathogen molecules and pathogens simulating human heat shock protein via pattern recognition receptors, thus it causes their own activation, sensitizes NF-κB pathway, induces the production of inflammatory mediators, leads the chronic inflammation and promotes thrombosis. Some studies reported that nearly 17% of the new tumors can be caused by chronic inflammation, and it seems that there is a complicated relationship between inflammasome and cancer-associated thrombosis.This article summarizes the correlation between inflammasome and cancer-associated thrombosis, and some of these theories have confirmed the relationship between them.
authors.affiliation: Institute of Hematology, Clinical Medical College of Yangzhou University,Subei People's Hospital of Jiangsu Province,Yangzhou 225001,Jiangsu Province,China.
authors.forename: Jing-Zheng
authors.initials: JZ
authors.lastname: Zhang
authors.affiliation: Institute of Hematology, Clinical Medical College of Yangzhou University,Subei People's Hospital of Jiangsu Province,Yangzhou 225001,Jiangsu Province,China.E-mail：maolujiu918@163.com.
authors.forename: Jian
authors.initials: J
authors.lastname: Gu
mesh_terms: D006360:Heat-Shock Proteins; D006801:Humans; D058847:Inflammasomes; D007249:Inflammation; D016328:NF-kappa B; D009369:Neoplasms; D013927:Thrombosis
chemical_list: D006360:Heat-Shock Proteins; D058847:Inflammasomes; D016328:NF-kappa B