title: The synthesis of substituted phosphathiahelicenes via regioselective bromination of a preformed helical scaffold: a new approach to modular ligands for enantioselective gold-catalysis.
abstract: Substituted phosphathiahelicenes have been prepared via a straightforward two-step procedure involving the regioselective bromination of a preformed helical scaffold, followed by palladium catalyzed coupling reactions. The new helicenes have been used as ligands in gold(i)-catalyzed [4+2] cyclizations of 1,6-enynes. The resulting dihydro-cyclopenta[b]naphthalene derivative was obtained in excellent yields and with up to 91% ee.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Univ. Paris-Sud, Université Paris-Saclay, 1, av. de la Terrasse, 91198 Gif-sur-Yvette, France. angela.marinetti@cnrs.fr arnaud.voituriez@cnrs.fr.
authors.forename: Paul
authors.initials: P
authors.lastname: Aillard
authors.forename: Davide
authors.initials: D
authors.lastname: Dova
authors.forename: Valentin
authors.initials: V
authors.lastname: Magné
authors.forename: Pascal
authors.initials: P
authors.lastname: Retailleau
authors.forename: Silvia
authors.initials: S
authors.lastname: Cauteruccio
authors.forename: Emanuela
authors.initials: E
authors.lastname: Licandro
authors.forename: Arnaud
authors.initials: A
authors.lastname: Voituriez
authors.forename: Angela
authors.initials: A
authors.lastname: Marinetti