title: Interocular Comparison of Anterior and Posterior Segment Findings and Laterality in Hyperopic Anisometropia.
abstract: OBJECTIVE
  To investigate the laterality and the differences in anterior and posterior segment findings in hyperopic patients with anisometropia between their eyes using spectral domain optical coherence tomography and LenStar LS-900 device.
  
  
  METHODS
  This prospective institutional study included hyperopic anisometropic patients with and without amblyopia, aged between 6 and 40 years. The refractive error and the values of keratometry, axial length (AL), central corneal thickness (CCT), peripapillary retinal nerve fiber layer (RNFL) thickness, and central macular thickness (CMT) obtained using the RK-F1 autorefractor, LenStar LS-900, and Spectralis optical coherence tomography were compared between the higher hyperopic and fellow eyes.
  
  
  RESULTS
  Eighty of the patients had hyperopic anisometropia with amblyopia and 30 of them had hyperopic anisometropia without amblyopia. The left eyes of the patients in this series were significantly more commonly affected. Axial length and CCT were significantly different between the higher hyperopic and the fellow eyes of all patients. In addition, the mean CMT and RNFL thickness of the higher hyperopic eyes were significantly higher than that of the fellow eyes.
  
  
  CONCLUSIONS
  During the process of emmetropization and development of the retina, higher hyperopic eyes in hyperopic patients with anisometropia and amblyopic eyes may have blurred and abnormal vision, leading to under-development of vision, significantly higher CCT, CMT, and RNFL thickness, more hyperopic refraction, and shorter AL in the affected eye.
authors.affiliation: Ophthalmology Department, Ankara Ulucanlar Eye Research Hospital, Ankara, Turkey.
authors.forename: Veysel
authors.initials: V
authors.lastname: Cankurtaran
authors.forename: Kemal
authors.initials: K
authors.lastname: Tekin
authors.forename: Mert
authors.initials: M
authors.lastname: Şimşek
authors.forename: Ufuk
authors.initials: U
authors.lastname: Elgin
authors.forename: Pelin
authors.initials: P
authors.lastname: Yilmazbaş
mesh_terms: D000293:Adolescent; D000328:Adult; D015858:Anisometropia / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D000869:Anterior Eye Segment / Q000000981:diagnostic imaging*; D002648:Child; D018450:Disease Progression; D015785:Eye Diseases, Hereditary / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006956:Hyperopia / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D057972:Posterior Eye Segment / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D012029:Refraction, Ocular; D012165:Retinal Ganglion Cells / Q000473:pathology; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity; D055815:Young Adult