title: [Genetic Control of Circadian Rhythms and Aging].
abstract: The review establishes a link between a group of genes which are conserved in evolution and form a molecular oscillator responsible for generation of circadian rhythms and genetic determinants of aging including associated pathways of intracellular signaling. An analysis of mechanisms of development of age-dependent pathologies is conducted from the viewpoint of circadian genetics. Systematic data of circadian gene expression studies in animals demonstrating different rates of aging from accelerated to negligible are presented.
authors.forename: I A
authors.initials: IA
authors.lastname: Solovyeva
authors.forename: E V
authors.initials: EV
authors.lastname: Dobrovolskayaa
authors.forename: A A
authors.initials: AA
authors.lastname: Moskalev
mesh_terms: D000375:Aging / Q000235:genetics* / Q000473:pathology; D000818:Animals; D002940:Circadian Rhythm / Q000235:genetics*; D019143:Evolution, Molecular; D005786:Gene Expression Regulation; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000145:classification / Q000235:genetics*
chemical_list: D047908:Intracellular Signaling Peptides and Proteins