title: Which is the best intrauterine insemination timing choice following exogenous hCG administration during ovulation induction by using clomiphene citrate treatment? A retrospective study.
abstract: OBJECTIVE
  To evaluate the impact of intrauterine insemination timing performed 24 or 36 h later following ovulation trigger on clinical pregnancy rate during ovulation induction with clomiphene citrate among infertile women was the objective of this study.
  
  
  METHODS
  The medical records of 280 infertile patients who have underwent ovulation induction by using clomiphene citrate have been evaluated and cycle outcomes of the patients have been investigated specifically based on the timing of intrauterine insemination during the treatment cycle.
  
  
  RESULTS
  The clinical pregnancy rate of the study group based on the timing of intrauterine insemination (24 vs. 36 h following hCG trigger) was found to be similar regardless of infertility type. The cycle day of which hCG trigger has been performed was found to be significantly longer for patients who have achieved clinical pregnancy than patients who have not got pregnant following the treatment cycle. Dominant follicle diameter has not been found to affect clinical pregnancy rate during treatment cycles with clomiphene citrate.
  
  
  CONCLUSIONS
  In this study, intrauterine insemination timing did not affect the cycle outcomes whether the procedure has been performed 24 or 36 h later following ovulation trigger with exogenous hCG utilization. The longer period of treatment cycle during ovulation induction with clomiphene citrate resulted with higher clinical pregnancy rate. Intrauterine insemination can be done successfully at either 24 or 36 h after hCG in clomiphene citrate stimulated cycles. This will allow more flexibility and convenience for both physicians and patients, especially during weekends.
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Omer Hamid
authors.initials: OH
authors.lastname: Yumusak
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Kahyaoglu
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Meryem Kuru
authors.initials: MK
authors.lastname: Pekcan
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Isci
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Şebnem
authors.initials: Ş
authors.lastname: Ozyer
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Mahmut Nedim
authors.initials: MN
authors.lastname: Cicek
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Tasci
authors.affiliation: Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Education and Research Hospital, Hamamonu-Altindag, Ankara Turkey.
authors.forename: Salim
authors.initials: S
authors.lastname: Erkaya
keywords: Clinical pregnancy; Clomiphene citrate; Infertility; Intrauterine insemination