title: Influence of a Magnetic Field and Laser Therapy on the Quality of Mandibular Bone During Distraction Osteogenesis in Rabbits.
abstract: OBJECTIVE
  This study evaluated the use of low-level laser therapy (LLLT) and exposure to a magnetic field (MF) during distraction osteogenesis.
  
  
  METHODS
  The sample consisted of 18 rabbits divided into 3 groups of 6 animals each: control, MF exposure (briefly, magnetized gold-coated washers were placed next to the distractor device), and LLLT exposure (830 nm applied every 48 hours over 4 points [dose, 5 J/cm2] during the consolidation period). The same distraction osteogenesis protocol was used in all 3 groups (0.5 mm every 12 hours for 1 week).
  
  
  RESULTS
  Quantitative microscopic analysis of sections stained with hematoxylin and eosin showed a statistically significant difference in the amount of newly formed bone in the MF group compared with the LLLT group (P = .006). The number of cells with more than 3 argyrophilic nucleolar organizer regions also was significantly different between the LLLT and control groups (P = .038).
  
  
  CONCLUSIONS
  Distraction osteogenesis effectively promoted bone lengthening. The LLLT group exhibited a larger amount of newly formed bone and a larger number of osteoblasts in the cell division phase, but the difference was not statistically relevant compared with the control group.
authors.affiliation: Professor, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre; Professor, Department of Oral and Maxillofacial Surgery, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address: angelofreddo@gmail.com.
authors.forename: Angelo Luiz
authors.initials: AL
authors.lastname: Freddo
authors.affiliation: Department of Oral and Maxillofacial Surgery, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
authors.forename: Caroline Comis
authors.initials: CC
authors.lastname: Giongo
authors.affiliation: Professor, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre; Professor, Department of Oral and Maxillofacial Surgery, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
authors.forename: Deise
authors.initials: D
authors.lastname: Ponzoni
authors.affiliation: Professor, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Corsetti
authors.affiliation: Professor, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre; Professor and Department Head, Department of Oral and Maxillofacial Surgery, Santa Casa de Misericórdia Dental Center, Porto Alegre, RS, Brazil.
authors.forename: Edela
authors.initials: E
authors.lastname: Puricelli
mesh_terms: D000818:Animals; D005260:Female; D007259:Infrared Rays; D028022:Low-Level Light Therapy; D060526:Magnetic Fields; D008334:Mandible / Q000033:anatomy & histology / Q000502:physiology / Q000601:surgery*; D010012:Osteogenesis / Q000528:radiation effects; D019857:Osteogenesis, Distraction / Q000379:methods*; D017063:Outcome Assessment, Health Care; D011817:Rabbits