title: Precision medicine: what's all the fuss about?
abstract: Precision medicine is now recognized globally as a major new era in medicine. It is being driven by advances in genomics and other 'omics' but also by the desire on the part of both health systems and governments to offer more targeted and cost-effective care. However, it faces a number of challenges, from the economics of developing more expensive companion diagnostics to the need to educate patients and the public on the advantages for them. New models of both R&D and care delivery are needed to capture the scientific, clinical and economic benefits of precision medicine.
authors.affiliation: a Centre for the Advancement of Sustainable Medical Innovation (CASMI) and Precision Medicine Catapult, University of Oxford , Oxford , UK.
authors.forename: Richard
authors.initials: R
authors.lastname: Barker
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D003695:Delivery of Health Care / Q000458:organization & administration*; D057069:Diagnostic Test Approval / Q000331:legislation & jurisprudence; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000191:economics* / Q000379:methods / Q000592:standards; D057285:Precision Medicine / Q000191:economics / Q000941:ethics / Q000639:trends*; D000071696:Proteogenomics / Q000191:economics / Q000295:instrumentation / Q000379:methods*; D011933:Reagent Kits, Diagnostic
chemical_list: D015415:Biomarkers; D011933:Reagent Kits, Diagnostic
keywords: Companion diagnostics; ethical issues; genomics; molecular taxonomy; precision medicine; proteomics; regulatory approval; reimbursement; transcriptomics