title: [Gastric Mucormycosis Followed by Traumatic Cardiac Rupture in an Immunocompetent Patient].
abstract: Gastric mucormycosis is a rare and life-threatening fungal disease, caused by fungus in the order Mucorales. While rhino-cerebral and pulmonary forms are common, gastric mucormycosis is an uncommon site for the disease. We diagnosed gastric mucormycosis in a 41-year-old female who had severe multiple trauma, including cardiac rupture, due to a traffic accident. Eighteen days after hospitalization, she passed 800 mL of melena over one day. We performed upper esophagogastroduodenoscopy (EGD) and found a huge gastric ulcer with bleeding. Histopathological examination identified non-septated and right-angled branching fungal hyphae, and we diagnosed gastric mucormycosis. We recommended total gastrectomy to her but she refused the operation, so she was treated with liposomal amphotericin B for 53 days. After two months of treatment with liposomal amphotericin B, we again performed EGD and found a healed gastric ulcer. After four months, with another EGD, we found that the gastric mucormycosis was completely healed.
authors.affiliation: Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Sang Won
authors.initials: SW
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Hyun Seok
authors.initials: HS
authors.lastname: Lee
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D016145:Endoscopy, Digestive System; D005260:Female; D006335:Heart Injuries / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D009090:Mucorales / Q000302:isolation & purification; D009091:Mucormycosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D013276:Stomach Ulcer / Q000175:diagnosis / Q000209:etiology; D014057:Tomography, X-Ray Computed
chemical_list: C068538:liposomal amphotericin B; D000666:Amphotericin B
keywords: Amphotericin B; Gastric mucormycosis; Heart rupture; Immunocompetent