title: Idiopathic nasal bone osteitis: A preliminary report on a recently recognized entity.
abstract: Osteitis of the nasal bones is a rare disease; when it occurs, it usually has a known etiology. To the best of our knowledge, idiopathic nasal bone osteitis (NBO) has not been described before. We conducted a study to analyze the behavior of idiopathic NBO and its outcome and to determine a cutoff level for diagnosis using technetium-99m-methylene-diphosphonate (Tc-MDP) bone scanning. This retrospective, controlled analysis involved 9 women (mean age: 44 yr) who had been admitted to an otolaryngology department in Israel with idiopathic NBO over a 5-year period. Clinical evaluation, isotopic evaluation, and computed tomography were done. A lesion-to-nonlesion ratio was calculated between an area of interest on the nasal bone and a reference point (L/R ratio). The same ratio was calculated for a control group of 20 subjects. All the Tc-MDP scans in the study group were suggestive of osteitis. Intravenous antibiotic treatment was effective in all cases. A high degree of accuracy was achieved with cutoff L/R ratios of 2.05 for planar views and 2.34 for single-photon emission computed tomography views.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Rabin Medical Center, 39 Jabotinski St., Petah Tikva, Israel 4941492. yotam80@gmail.com.
authors.forename: Yotam
authors.initials: Y
authors.lastname: Shkedy
authors.forename: Ohad
authors.initials: O
authors.lastname: Ronen
authors.forename: Sarah
authors.initials: S
authors.lastname: Gips
authors.forename: Avi
authors.initials: A
authors.lastname: Front
authors.forename: Tal
authors.initials: T
authors.lastname: Marshak
authors.forename: Nechama
authors.initials: N
authors.lastname: Uri
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D009295:Nasal Bone / Q000000981:diagnostic imaging*; D010000:Osteitis / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging / Q000379:methods*; D019275:Radiopharmaceuticals; D012016:Reference Values; D012189:Retrospective Studies; D013669:Technetium Tc 99m Medronate; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate