title: Circumorificial plasmacytosis/plasma cell orificial mucositis: a case series and a review of the literature.
abstract: Circumorificial plasmacytosis is a rare plasma cell proliferative disorder of the orificial mucous membranes. The etiology is unknown, and there are no reported effective treatments to date. We report three cases of idiopathic circumorificial plasmacytosis with varying clinical presentations and responses to treatment, including a first reported case of resolution with adalimumab therapy.
authors.affiliation: Specialist Registrar in Oral Medicine, Department of Oral and Maxillofacial Surgery, Oral Medicine, Oral Pathology and Radiology, Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland. Electronic address: sheila.galvin@dental.tcd.ie.
authors.forename: Sheila
authors.initials: S
authors.lastname: Galvin
authors.affiliation: Registrar in Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, St James's Hospital, Dublin, Ireland.
authors.forename: Conor
authors.initials: C
authors.lastname: Bowe
authors.affiliation: Consultant Pathologist, Department of Oral and Maxillofacial Surgery, Oral Medicine, Oral Pathology and Radiology, Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland; Department of Pathology, St James's Hospital, Dublin, Ireland.
authors.forename: Esther M
authors.initials: EM
authors.lastname: O Regan
authors.affiliation: Consultant Immunologist, Department of Immunology, St James's Hospital, Dublin, Ireland.
authors.forename: Niall
authors.initials: N
authors.lastname: Conlon
authors.affiliation: Professor of Oral Medicine, Department of Oral and Maxillofacial Surgery, Oral Medicine, Oral Pathology and Radiology, Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland.
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Flint
authors.affiliation: Consultant in Oral Medicine, Department of Oral and Maxillofacial Surgery, Oral Medicine, Oral Pathology and Radiology, Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland.
authors.forename: Claire M
authors.initials: CM
authors.lastname: Healy
mesh_terms: D000068879:Adalimumab / Q000627:therapeutic use*; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D052016:Mucositis / Q000175:diagnosis* / Q000188:drug therapy*; D010950:Plasma Cells / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents; D000068879:Adalimumab