title: Iodine in food- and dietary supplement-composition databases.
abstract: The US Food and Drug Administration (FDA) and the Nutrient Data Laboratory (NDL) of the USDA Agricultural Research Service have worked independently on determining the iodine content of foods and dietary supplements and are now harmonizing their efforts. The objective of the current article is to describe the harmonization plan and the results of initial iodine analyses accomplished under that plan. For many years, the FDA's Total Diet Study (TDS) has measured iodine concentrations in selected foods collected in 4 regions of the country each year. For more than a decade, the NDL has collected and analyzed foods as part of the National Food and Nutrient Analysis Program; iodine analysis is now being added to the program. The NDL recently qualified a commercial laboratory to conduct iodine analysis of foods by an inductively coupled plasma mass spectrometry (ICP-MS) method. Co-analysis of a set of samples by the commercial laboratory using the ICP-MS method and by the FDA laboratory using its standard colorimetric method yielded comparable results. The FDA recently reviewed historical TDS data for trends in the iodine content of selected foods, and the NDL analyzed samples of a limited subset of those foods for iodine. The FDA and the NDL are working to combine their data on iodine in foods and to produce an online database that can be used for estimating iodine intake from foods in the US population. In addition, the NDL continues to analyze dietary supplements for iodine and, in collaboration with the NIH Office of Dietary Supplements, to publish the data online in the Dietary Supplement Ingredient Database. The goal is to provide, through these 2 harmonized databases and the continuing TDS focus on iodine, improved tools for estimating iodine intake in population studies.
authors.affiliation: Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, USDA, Beltsville, MD; pamela.pehrsson@ars.usda.gov.
authors.forename: Pamela R
authors.initials: PR
authors.lastname: Pehrsson
authors.affiliation: Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, USDA, Beltsville, MD;
authors.forename: Kristine Y
authors.initials: KY
authors.lastname: Patterson
authors.affiliation: Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, MD; and.
authors.forename: Judith H
authors.initials: JH
authors.lastname: Spungen
authors.affiliation: Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, MD; and.
authors.forename: Mark S
authors.initials: MS
authors.lastname: Wirtz
authors.affiliation: Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, USDA, Beltsville, MD;
authors.forename: Karen W
authors.initials: KW
authors.lastname: Andrews
authors.affiliation: Office of Dietary Supplements, NIH, Bethesda, MD.
authors.forename: Johanna T
authors.initials: JT
authors.lastname: Dwyer
authors.affiliation: Office of Dietary Supplements, NIH, Bethesda, MD.
authors.forename: Christine A
authors.initials: CA
authors.lastname: Swanson
mesh_terms: D016208:Databases, Factual; D004032:Diet; D019587:Dietary Supplements; D005504:Food Analysis / Q000379:methods*; D006801:Humans; D020407:Internet; D007455:Iodine / Q000008:administration & dosage / Q000032:analysis*; D014481:United States; D016885:United States Department of Agriculture
chemical_list: D007455:Iodine
keywords: DSID; FDA; NHANES; Total Diet Study; USDA