title: Canadian Registry of LVIS Jr for Treatment of Intracranial Aneurysms (CaRLA).
abstract: BACKGROUND
  Stents reduce the rate of angiographic recurrence of intracranial aneurysms. The newest stent for intracranial use is the Low-profile Visible Intraluminal Support device (LVIS Jr).
  
  
  OBJECTIVE
  To assess the efficacy of the new stent in a multicenter retrospective registry.
  
  
  METHODS
  Centers across Canada using LVIS Jr were contacted and asked to participate in a retrospective registry of consecutive patients treated with LVIS Jr for intracranial aneurysms between January 2013 and July 2015.
  
  
  RESULTS
  A total of 102 patients, with saccular aneurysms in 100 patients (72 women; age range 21-78 years; mean 56.0 years; median 57.5 years) were treated with a LVIS Jr stent. The mean maximum diameter of the dome and neck of the aneurysm and dome to neck ratios were 8.3 mm±7.7 mm, 4.4 mm±1.9 mm, and 1.86±1.22, respectively. Angiographic complications arose in 23 patients, clinical complications in 9 patients, and only 3% of permanent neurological deficits occurred. Death occurred in 1 patient, unrelated to the stent. The ruptured status of the aneurysms (OR=3.29; p=0.046) and use of LVIS Jr for bailout (OR=2.54; p=0.053) showed a trend towards significant association with higher angiographic complications. At the last available follow-up, 68 class I, 20 class II, and 12 class III results were seen.
  
  
  CONCLUSIONS
  The LVIS Jr stent is a safe and effective device for stent-assisted coiling, with 3% permanent neurological complications. Stent-assisted coiling continues to be technically challenging in cases of ruptured aneurysms and bailout situations.
authors.affiliation: Department of Diagnostic Imaging, QE II Health Sciences Centre, Halifax, Nova Scotia, Canada.
authors.forename: Jai Jai Shiva
authors.initials: JJS
authors.lastname: Shankar
authors.affiliation: Division of Neuroradiology, Department of Diagnostic Imaging, The Ottawa Hospital, Ottawa, Canada.
authors.forename: Aiman
authors.initials: A
authors.lastname: Quateen
authors.affiliation: Department of Radiology, Centre hospitalier de l'Université de Montréal (CHUM), Hopital Notre-Dame, Montreal, Quebec, Canada.
authors.forename: Alain
authors.initials: A
authors.lastname: Weill
authors.affiliation: Departments of Radiology, Neurology, and Neurosurgery, Montreal Neurological Hospital and Institute, Montreal, Quebec, Canada.
authors.forename: Donatella
authors.initials: D
authors.lastname: Tampieri
authors.affiliation: Department of Radiology, Montreal Neurological Hospital and Institute, Montreal, Quebec, Canada.
authors.forename: Maria
authors.initials: M
authors.lastname: Del Pilar Cortes
authors.affiliation: Department of Radiology, Centre hospitalier de l'Université de Montréal (CHUM), Hopital Notre-Dame, Montreal, Quebec, Canada.
authors.forename: Robert
authors.initials: R
authors.lastname: Fahed
authors.affiliation: Division of Neuroradiology, Department of Diagnostic Imaging, The Ottawa Hospital, Ottawa, Canada.
authors.forename: Satya
authors.initials: S
authors.lastname: Patro
authors.affiliation: Section of Neurosurgery, Health Sciences Centre, Winnipeg, Canada.
authors.forename: Zul
authors.initials: Z
authors.lastname: Kaderali
authors.affiliation: Division of Neuroradiology, Department of Diagnostic Imaging, The Ottawa Hospital, Ottawa, Canada.
authors.forename: Cheemun
authors.initials: C
authors.lastname: Lum
authors.affiliation: Department of Neurosurgery, The Ottawa Hospital, Ottawa, Canada.
authors.forename: Howard
authors.initials: H
authors.lastname: Lesiuk
authors.affiliation: Department of Neurosurgery, University of Saskatchewan, Saskatoon, Canada.
authors.forename: Uzair
authors.initials: U
authors.lastname: Ahmed
authors.affiliation: Department of Neurosurgery, University of Saskatchewan, Saskatoon, Canada.
authors.forename: Lissa
authors.initials: L
authors.lastname: Peeling
authors.affiliation: Departments of Neurosurgery, Medical Imaging, Biomedical Engineering, & Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, Canada.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Kelly
authors.affiliation: Division of Neuroradiology, Department of Diagnostic Imaging, The Ottawa Hospital, Ottawa, Canada.
authors.forename: Daniela
authors.initials: D
authors.lastname: Iancu
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000601:surgery*; D002170:Canada / Q000453:epidemiology; D002533:Cerebral Angiography / Q000379:methods; D004621:Embolization, Therapeutic / Q000379:methods; D057510:Endovascular Procedures / Q000379:methods; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012042:Registries; D012189:Retrospective Studies; D015607:Stents / Q000592:standards*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Aneurysm; Coil; Device; Intervention; Stent