title: Esophageal Cancer.
abstract: Esophageal cancer carries a poor prognosis among gastrointestinal malignancies. Although esophageal squamous cell carcinoma predominates worldwide, Western nations have seen a marked rise in the incidence of esophageal adenocarcinoma that parallels the obesity epidemic. Efforts directed toward early detection have been difficult, given that dysplasia and early cancer are generally asymptomatic. However, significant advances have been made in the past 10 to 15 years that allow for endoscopic management and often cure in early stage esophageal malignancy. New diagnostic imaging technologies may provide a means by which cost-effective, early diagnosis of dysplasia allows for definitive therapy and ultimately improves the overall survival among patients.
authors.affiliation: Department of Gastroenterology and Hepatology, Kansas City VA Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, USA; Department of Gastroenterology and Hepatology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Mailstop 1023, Kansas City, KS 66160, USA. Electronic address: benjamin.alsop@va.gov.
authors.forename: Benjamin R
authors.initials: BR
authors.lastname: Alsop
authors.affiliation: Department of Gastroenterology and Hepatology, Kansas City VA Medical Center, 4801 Linwood Boulevard, Kansas City, MO 64128, USA; Department of Gastroenterology and Hepatology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Mailstop 1023, Kansas City, KS 66160, USA.
authors.forename: Prateek
authors.initials: P
authors.lastname: Sharma
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D001471:Barrett Esophagus / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D055088:Early Detection of Cancer; D061345:Early Medical Intervention; D000069916:Endoscopic Mucosal Resection; D016145:Endoscopy, Digestive System; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000077277:Esophageal Squamous Cell Carcinoma; D006801:Humans; D009367:Neoplasm Staging; D057832:Watchful Waiting
keywords: Barrett’s esophagus; Esophageal adenocarcinoma; Esophageal squamous cell carcinoma; Esophagus cancer