title: Dataset of aqueous humor cytokine profile in HIV patients with Cytomegalovirus (CMV) retinitis.
abstract: The data shows the aqueous humor cytokine profiling results acquired in a small cohort of 17 HIV patients clinically diagnosed with Cytomegalovirus retinitis using the FlexMAP 3D (Luminex®) platform using the Milliplex Human Cytokine® kit. Aqueous humor samples were collected from these patients at different time points (pre-treatment and at 4-weekly intervals through the 12-week course of intravitreal ganciclovir treatment) and 41 cytokine levels were analyzed at each time point. CMV DNA viral load was assessed in 8 patients at different time points throughout the course of ganciclovir treatment. The data described herein is related to the research article entitled "Aqueous humor immune factors and cytomegalovirus (CMV) levels in CMV retinitis through treatment - The CRIGSS study" (Iyer et al., 2016) [1]. Cytokine levels against the different time points which indicate the response to the given treatment and against the CMV viral load were analyzed.
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore; Singapore National Eye Center, Singapore.
authors.forename: Jayant Venkatramani
authors.initials: JV
authors.lastname: Iyer
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
authors.forename: Rupesh
authors.initials: R
authors.lastname: Agrawal
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
authors.forename: Tun Kuan
authors.initials: TK
authors.lastname: Yeo
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
authors.forename: Dinesh V
authors.initials: DV
authors.lastname: Gunasekeran
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
authors.forename: Praveen Kumar
authors.initials: PK
authors.lastname: Balne
authors.affiliation: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A STAR), Singapore.
authors.forename: Bernett
authors.initials: B
authors.lastname: Lee
authors.affiliation: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A STAR), Singapore.
authors.forename: Veonice Bijin
authors.initials: VB
authors.lastname: Au
authors.affiliation: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (ASTAR), Singapore; Institute of Biomedical Studies, Baylor University, Waco, TX, USA.
authors.forename: John
authors.initials: J
authors.lastname: Connolly
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
authors.forename: Stephen C B
authors.initials: SC
authors.lastname: Teoh
keywords: CMV retinitis; Cytokines; Dataset; HIV; Luminex bead assay