title: Preoperative Percutaneous Transthoracic Needle Biopsy Increased the Risk of Pleural Recurrence in Pathological Stage I Lung Cancer Patients With Sub-pleural Pure Solid Nodules.
abstract: We retrospectively evaluated whether preoperative percutaneous transthoracic needle biopsy (PTNB) affected the incidence of pleural recurrence in pathological stage I lung cancer patients. Pleural recurrence occurred in pure solid nodule (PSN) cases but not in ground-glass nodule cases, as evaluated using thin-section computed tomographic imaging. When the cases were restricted to sub-pleural PSN, the incidence of recurrence tended to be higher in a PTNB group (63 patients diagnosed by PTNB) than in a non-PTNB group (86 patients diagnosed by transbronchial biopsy or intraoperative diagnosis) (25% vs. 4%, p =.050). PTNB should not be performed in patients with a sub-pleural PSN.
authors.affiliation: a Department of Respiratory Medicine , Kumamoto Regional Medical Center , Kumamoto , Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Kashiwabara
authors.affiliation: a Department of Respiratory Medicine , Kumamoto Regional Medical Center , Kumamoto , Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Semba
authors.affiliation: a Department of Respiratory Medicine , Kumamoto Regional Medical Center , Kumamoto , Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Fujii
authors.affiliation: a Department of Respiratory Medicine , Kumamoto Regional Medical Center , Kumamoto , Japan.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Tsumura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000009:adverse effects* / Q000379:methods; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010997:Pleural Neoplasms / Q000175:diagnosis*; D011300:Preoperative Care; D012189:Retrospective Studies; D012306:Risk; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden
keywords: Pleural recurrence; needle-tract implantation; percutaneous transthoracic needle biopsy; pure solid nodule; sub-pleural location