title: Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice.
abstract: BACKGROUND The aim of this study was to investigate the variety of plasma contents of membrane glycolipids in 65 gastrointestinal tumors and 31 transplant hepatomas in mice. MATERIAL AND METHODS The experimental model was a transplantable murine hepatoma. Experimental mice were divided into 3 groups. RESULTS The LSA and TSA content in the 2 groups were significantly difference (p<0.01), and were significantly lower in the therapeutic group than in the control group (p<0.01). CONCLUSIONS These results indicate that membrane glycolipids index LSA and TSA are sensitive markers in gastrointestinal tumors. In the transplanted hepatomas in mice, they may be considered as ancillary indicators for judging the therapeutic effect of hepatoma.
authors.affiliation: Department of Biochemistry, Wannan Medical College, Wuhu, Anhui, China (mainland).
authors.forename: Jun
authors.initials: J
authors.lastname: Lv
authors.affiliation: Department of Biochemistry, Wannan Medical College, Wuhu, Anhui, China (mainland).
authors.forename: Can Qun
authors.initials: CQ
authors.lastname: Lv
authors.affiliation: Department of Biochemistry, Wannan Medical College, Wuhu, Anhui, China (mainland).
authors.forename: Bo-Liang
authors.initials: BL
authors.lastname: Wang
authors.affiliation: Department of Biochemistry, Wannan Medical College, Wuhu, Anhui, China (mainland).
authors.forename: Ping
authors.initials: P
authors.lastname: Mei
authors.affiliation: Department of Biochemistry, Wannan Medical College, Wuhu, Anhui, China (mainland).
authors.forename: Lei
authors.initials: L
authors.lastname: Xu
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000097:blood*; D005472:Fluorouracil / Q000494:pharmacology; D005770:Gastrointestinal Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000473:pathology; D006017:Glycolipids / Q000097:blood*; D008114:Liver Neoplasms, Experimental / Q000097:blood* / Q000188:drug therapy / Q000473:pathology; D051379:Mice; D009368:Neoplasm Transplantation
chemical_list: D014408:Biomarkers, Tumor; D006017:Glycolipids; D005472:Fluorouracil