title: Historical distribution of central nervous system tumors in the Mexican National Institute of Neurology and Neurosurgery.
abstract: OBJECTIVE
  To determine the frequency of central nervous system (CNS) tumors in the first fifty years of the National Institute of Neurology and Neurosurgery of Mexico Manuel Velasco Suárez (Instituto Nacional de Neurología y Neurocirugía de México, INNN) from 1965 to 2014.
  
  
  METHODS
  A total of 16 116 institutional records of CNS tumors were analyzed. The frequency and distribution of CNS tumors were evaluated by tumor type, patient age and patient gender. The annual relationship between CNS tumors and surgical discharges (SD) over the last 20 years was estimated.
  
  
  RESULTS
  The frequencies of most CNS tumors were consistent with those found worldwide, and the most common tumors were neuroepithelial tumors (33%), particularly astrocytic tumors (67%); meningeal tumors (26%); and pituitary tumors (20%). The incidence of pituitary tumors in these data was twice as high as that reported in other regions of the world, and the relationship between CNS tumors and SD was consistent over time (0.22-0.39).
  
  
  CONCLUSIONS
  This study summarizes the largest sample of CNS tumor cases analyzed in Mexico and provides an important reference of the frequency of this tumor type in the country. This work will serve as a basis for conducting studies evaluating factors associated with the presence of CNS tumors and for identifying adequate public health interventions.
authors.forename: Lucinda
authors.initials: L
authors.lastname: Aguirre-Cruz
authors.forename: Edgar
authors.initials: E
authors.lastname: Rangel-López
authors.forename: Dora Luz de la
authors.initials: DL
authors.lastname: Cruz-Aguilera
authors.forename: Citlali Ekaterina
authors.initials: CE
authors.lastname: Rodríguez-Pérez
authors.forename: Luis
authors.initials: L
authors.lastname: Ruano
authors.forename: Leora
authors.initials: L
authors.lastname: Velásquez-Pérez
authors.forename: Mauricio
authors.initials: M
authors.lastname: Martínez-Moreno
authors.forename: Juan
authors.initials: J
authors.lastname: Garduño-Espinosa
authors.forename: Julio
authors.initials: J
authors.lastname: Sotelo
mesh_terms: D000047:Academies and Institutes / Q000266:history* / Q000706:statistics & numerical data; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000266:history* / Q000473:pathology; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D015994:Incidence; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009462:Neurology / Q000266:history*; D009493:Neurosurgery / Q000266:history*; D010911:Pituitary Neoplasms / Q000453:epidemiology / Q000266:history; D012189:Retrospective Studies; D055815:Young Adult