title: Nickel-catalyzed C-N bond reduction of aromatic and benzylic quaternary ammonium triflates.
abstract: A nickel-catalyzed, efficient C-N bond reduction of aromatic and benzylic ammonium triflates has been developed using sodium isopropoxide as a reducing agent. The high efficiency, mild conditions, and good compatibility with various substituents made this method an effective supplement to the current catalytic hydrogenation reactions. Combining this reductive deamination reaction with directed aromatic functionalization reactions, a powerful strategy for regioselective functionalization of arenes was demonstrated using dialkylamine groups as traceless directing groups.
authors.affiliation: State Key Laboratory and Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin, 300071, China. guan@nankai.edu.cn.
authors.forename: Yuan-Qiu-Qiang
authors.initials: YQ
authors.lastname: Yi
authors.forename: Wen-Cheng
authors.initials: WC
authors.lastname: Yang
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Zhai
authors.forename: Xiang-Yu
authors.initials: XY
authors.lastname: Zhang
authors.forename: Shuai-Qi
authors.initials: SQ
authors.lastname: Li
authors.forename: Bing-Tao
authors.initials: BT
authors.lastname: Guan