title: Outcome of cartilage at 12years of follow-up after anterior cruciate ligament reconstruction.
abstract: In cases of chronic anterior laxity, reconstruction of the anterior cruciate ligament (ACL) can slow the development of osteoarthritis. This study was conducted to determine the overall prevalence of osteoarthritis and to identify the risk factors after ACL reconstruction.
  
  
  
  Meniscus tears, time from injury to surgery, body mass index (BMI), residual laxity, and cartilage lesions influence the progression towards osteoarthritis.
  
  
  
  This multicenter, retrospective study on the outcome of cruciate ligaments at 12 years of follow-up was conducted within the 2014 SOFCOT Symposium. The cohort included 675 arthroscopic reconstructions of the ACL from January 2002 to December 2003. The clinical evaluation included the objective and subjective IKDC score. Osteoarthritis was analyzed on 589 knee X-rays according to the IKDC classification. The predictive factors of osteoarthritis development studied were age, gender, BMI, time from injury to surgery, activity level, medial or lateral meniscectomy, type of graft, medial or lateral chondropathy, tunnel positioning, and residual laxity. Univariate and multivariate analyses with logistic regression were performed.
  
  
  
  The mean follow-up was 11.9±0.8 years. The subjective IKDC score was 83.7±13. At 12 years, the rate of moderate to severe osteoarthritis l (IKDCC or D) was 19% (16% medial tibiofemoral osteoarthritis, 4% lateral tibiofemoral osteoarthritis, and 2% patellofemoral osteoarthritis). The prognostic factors were age at surgery greater than 34 years (P<0.05), cartilage lesions at surgery (P<0.05), medial or lateral meniscectomy (P<0.05), and residual laxity (P<0.05).
  
  
  
  This large-scale study identified risk factors for osteoarthritis that should improve the information provided to patients on long-term progression after ACL reconstruction.
  
  
  
  Retrospective cohort study, level IV.
authors.affiliation: Service de chirurgie orthopédique, centre Albert-Trillat, hôpital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69004 Lyon, France.
authors.forename: O
authors.initials: O
authors.lastname: Cantin
authors.affiliation: Service de chirurgie orthopédique, centre Albert-Trillat, hôpital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69004 Lyon, France. Electronic address: professeur.lustig@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Lustig
authors.affiliation: Service de chirurgie orthopédique, hôpital d'instruction des armées Desgenettes, 108, boulevard Pinel, 69003 Lyon, France.
authors.forename: F
authors.initials: F
authors.lastname: Rongieras
authors.affiliation: Clinique universitaire de chirurgie orthopédique et de traumatologie du sport, hôpital Sud, CHU de Grenoble, avenue de Kimberley, 38130 Échirolles, France.
authors.forename: D
authors.initials: D
authors.lastname: Saragaglia
authors.affiliation: Institut de l'appareil locomoteur Nollet, 75017 Paris, France; Clinique du sport Paris V, 75005 Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Lefèvre
authors.affiliation: Centre de consultation orthopédique et sportive, clinique du sport de Bordeaux-Mérignac, 2, rue Negrevergne, 33700 Mérignac, France.
authors.forename: N
authors.initials: N
authors.lastname: Graveleau
authors.affiliation: Département d'orthopédie-traumatologie, Unité Inserm COMETE, UMR U1075, CHU de Caen, avenue Côte-de-Nacre, 14000 Caen, France.
authors.forename: C
authors.initials: C
authors.lastname: Hulet
authors.affiliation: SoFCOT, 56, rue Boissonade, 75014 Paris, France.
mesh_terms: D000328:Adult; D000070598:Anterior Cruciate Ligament Injuries / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D059549:Anterior Cruciate Ligament Reconstruction; D002358:Cartilage, Articular / Q000503:physiopathology*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D020370:Osteoarthritis, Knee / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: Anterior cruciate ligament; Long-term outcomes; Meniscus; Osteoarthritis; Reconstruction