title: Induction to delivery interval using transcervical Foley catheter plus oxytocin and vaginal misoprostol: A comparative study at Aminu Kano Teaching Hospital, Kano, Nigeria.
abstract: BACKGROUND
  Induction of labor (IOL) is an artificial initiation of labor before its spontaneous onset for the purpose of delivery of the fetoplacental unit. Many factors are associated with its success in postdatism.
  
  
  OBJECTIVE
  To compare the induction delivery intervals using transcervical Foley catheter plus oxytocin and vaginal misoprostol, and to identify the factors associated with successful induction among postdate singleton multiparae.
  
  
  METHODS
  The study was a prospective randomized controlled trial of singleton multiparous pregnant women. They were randomized into two groups, one group for intravaginal misoprostol and the other group for transcervical Foley catheter insertion as a method of cervical ripening and IOL. The data were analyzed using SPSS version 17 computer software (SPSS Inc., IL, Chicago, USA). Comparisons of categorical variables were done using Chi-squared test, with P < 0.05 considered as significant. Student's t-test was used for continuous variables.
  
  
  RESULTS
  The incidence of postdatism was found to be 136 (13.1%). The mean induction delivery time interval was shorter in the misoprostol group 70 (5.54 ± 1.8 h) than in the Foley catheter oxytocin infusion group 66 (6.65 ± 1.7 h) (P = 0.035). There was, however, no statistically significant difference in the maternal and neonatal outcomes when these two agents were used for cervical ripening and IOL. Higher parity and higher Bishop's score were the factors found to be associated with high success rate of IOL (P < 0.001).
  
  
  CONCLUSIONS
  Vaginal misoprostol resulted in shorter induction delivery time interval as compared to transcervical Foley catheter. High parity and high Bishop's scores were the factors found to be associated with the success of IOL.
authors.affiliation: Department of Obstetrics and Gynaecology, Bayero University Kano, Aminu Kano Teaching Hospital, Kano, Nigeria.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Garba
authors.affiliation: Department of Obstetrics and Gynaecology, Aminu Kano Teaching Hospital, Kano, Nigeria.
authors.forename: Abubakar Shehu
authors.initials: AS
authors.lastname: Muhammed
authors.affiliation: Department of Obstetrics and Gynaecology, Bayero University Kano, Aminu Kano Teaching Hospital, Kano, Nigeria.
authors.forename: Zakari
authors.initials: Z
authors.lastname: Muhammad
authors.affiliation: Department of Obstetrics and Gynaecology, Bayero University Kano, Aminu Kano Teaching Hospital, Kano, Nigeria.
authors.forename: Hadiza Shehu
authors.initials: HS
authors.lastname: Galadanci
authors.affiliation: Department of Obstetrics and Gynaecology, Bayero University Kano, Aminu Kano Teaching Hospital, Kano, Nigeria.
authors.forename: Rabiu
authors.initials: R
authors.lastname: Ayyuba
authors.affiliation: Department of Obstetrics and Gynaecology, Bayero University Kano, Aminu Kano Teaching Hospital, Kano, Nigeria.
authors.forename: Idris Sulaiman
authors.initials: IS
authors.lastname: Abubakar
mesh_terms: D000282:Administration, Intravaginal; D000293:Adolescent; D000328:Adult; D002404:Catheterization / Q000379:methods*; D057785:Catheters; D020070:Cervical Ripening / Q000187:drug effects*; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D016595:Misoprostol / Q000008:administration & dosage*; D009549:Nigeria; D007744:Obstetric Labor Complications; D010120:Oxytocics / Q000008:administration & dosage*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D010120:Oxytocics; D016595:Misoprostol