title: Fractionation of parietal function in bistable perception probed with concurrent TMS-EEG.
abstract: When visual input has conflicting interpretations, conscious perception can alternate spontaneously between these possible interpretations. This is called bistable perception. Previous neuroimaging studies have indicated the involvement of two right parietal areas in resolving perceptual ambiguity (ant-SPLr and post-SPLr). Transcranial magnetic stimulation (TMS) studies that selectively interfered with the normal function of these regions suggest that they play opposing roles in this type of perceptual switch. In the present study, we investigated this fractionation of parietal function by use of combined TMS with electroencephalography (EEG). Specifically, while participants viewed either a bistable stimulus, a replay stimulus, or resting-state fixation, we applied single pulse TMS to either location independently while simultaneously recording EEG. Combined with participant's individual structural magnetic resonance imaging (MRI) scans, this dataset allows for complex analyses of the effect of TMS on neural time series data, which may further elucidate the causal role of the parietal cortex in ambiguous perception.
authors.affiliation: Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9RH, UK.|Centre for Integrative Neuroscience, University of Tübingen, Tübingen 72076, Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Schauer
authors.affiliation: Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9RH, UK.
authors.forename: Acer
authors.initials: A
authors.lastname: Chang
authors.affiliation: Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9RH, UK.
authors.forename: David
authors.initials: D
authors.lastname: Schwartzman
authors.affiliation: Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9RH, UK.|Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Brighton BN1 9RR, UK.
authors.forename: Charlotte L
authors.initials: CL
authors.lastname: Rae
authors.affiliation: Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9RH, UK.
authors.forename: Heather
authors.initials: H
authors.lastname: Iriye
authors.affiliation: Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9RH, UK.
authors.forename: Anil K
authors.initials: AK
authors.lastname: Seth
authors.affiliation: Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9RH, UK.|ARAYA Brain Imaging, Tokyo 102-0093, Japan.
authors.forename: Ryota
authors.initials: R
authors.lastname: Kanai
mesh_terms: D001931:Brain Mapping; D004569:Electroencephalography; D006801:Humans; D008279:Magnetic Resonance Imaging; D010296:Parietal Lobe / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation; D014796:Visual Perception