title: Efficacy and Safety of Endoscopic Ultrasound-guided Ethanol Ablation Therapy for Pancreatic Neuroendocrine Tumors.
abstract: Recently, endoscopic ultrasonography (EUS)-guided ethanol ablation for small pancreatic neuroendocrine tumors (p-NETs) has been reported. However, the efficacy and safety of the technique remain unclear. We have launched a prospective pilot study of EUS-guided ethanol ablation for p-NETs. The major eligibility criteria are the presence of a pathologically diagnosed grade (G) 1 or G2 p-NET, a tumor size of 2cm, and being a poor candidate for surgery. A total of 5 patients will be treated. The primary endpoint will be the complete ablation rate at 1 month after treatment.
authors.affiliation: Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.matsumotokazuyuki0227@yahoo.co.jp.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Hironari
authors.initials: H
authors.lastname: Kato
authors.forename: Koichiro
authors.initials: K
authors.lastname: Tsutsumi
authors.forename: Sho
authors.initials: S
authors.lastname: Mizukawa
authors.forename: Syuntaro
authors.initials: S
authors.lastname: Yabe
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Seki
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Akimoto
authors.forename: Daisuke
authors.initials: D
authors.lastname: Uchida
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tomoda
authors.forename: Naoki
authors.initials: N
authors.lastname: Yamamoto
authors.forename: Shigeru
authors.initials: S
authors.lastname: Horiguchi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Okada
mesh_terms: D055011:Ablation Techniques / Q000379:methods*; D002985:Clinical Protocols; D019160:Endosonography / Q000379:methods*; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D018358:Neuroendocrine Tumors / Q000628:therapy*; D010190:Pancreatic Neoplasms / Q000628:therapy*; D010865:Pilot Projects
chemical_list: D000431:Ethanol