title: Recent research progress on preparation and application of N, N, N-trimethyl chitosan.
abstract: N,N,N-trimethyl chitosan (TMC) is a quaternized chitosan derivative with excellent solubility in aqueous solutions. It has been extensively studied as an absorption enhancer, antibacterial agent and gene vector due to its ability to form complexes with anionic gels or macromoleculars. However, the research which describes the process of TMC preparation and its new applications has not been fully reviewed. In this paper, recent progress regarding different TMC preparation methods and its characterization and application in different fields is presented. Key findings are compared and summarized and some topics for further study are suggested.
authors.affiliation: Key Laboratory of Eco-textiles, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Pulp and Paper Science & Technology of Ministry of Education of China, Qilu University of Technology, Jinan 250353, China; Department of Chemical Engineering, University of New Brunswick, Fredericton E3B 5A3, Canada.
authors.forename: Meiyan
authors.initials: M
authors.lastname: Wu
authors.affiliation: Key Laboratory of Eco-textiles, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Pulp and Paper Science & Technology of Ministry of Education of China, Qilu University of Technology, Jinan 250353, China. Electronic address: longzhu@jiangnan.edu.cn.
authors.forename: Zhu
authors.initials: Z
authors.lastname: Long
authors.affiliation: Department of Chemical Engineering, University of New Brunswick, Fredericton E3B 5A3, Canada.
authors.forename: Huining
authors.initials: H
authors.lastname: Xiao
authors.affiliation: Key Laboratory of Pulp and Paper Science & Technology of Ministry of Education of China, Qilu University of Technology, Jinan 250353, China.
authors.forename: Cuihua
authors.initials: C
authors.lastname: Dong
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D048271:Chitosan / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004337:Drug Carriers; D052918:Environmental Restoration and Remediation; D018857:Food Packaging; D006801:Humans; D015394:Molecular Structure; D012995:Solubility
chemical_list: D000900:Anti-Bacterial Agents; D004337:Drug Carriers; C118071:N-trimethyl chitosan chloride; D048271:Chitosan
keywords: Application; N, N, N-trimethyl chitosan; Preparation methods; Research progress