title: Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers.
abstract: Mycotoxin contamination threatens health and life of humans and animals throughout the food supply chains. Many of the mycotoxins have been proven to be carcinogens, teratogens and mutagens. The reliable and sensitive sensing methods are requested to monitor mycotoxin contamination. Advanced sensors based on antibodies or aptamers boast the advantages of high sensitivity and rapidity, and have been used in the mycotoxin sensing. These sensors are miniaturized, thereby lowering costs, and are applicable to high-throughput modes. In this work, the latest developments in sensing strategies for mycotoxin determination were critically discussed. Optical and electrochemical sensing modes were compared. The sensing methods for single mycotoxin or multiple mycotoxins in food samples were reviewed, along with the challenges and the future of antibody or aptamer-based sensors. This work might promote academic studies and industrial applications for mycotoxin sensing.
authors.affiliation: Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. 15165385226@126.com.|Key Laboratory of Biology and Genetic Improvement of oil Crops, Ministry of Agriculture, Wuhan 430062, China. 15165385226@126.com.|Key Laboratory of Detection for Mycotoxins, Ministry of Agriculture, Wuhan 430062, China. 15165385226@126.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
authors.affiliation: Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. zwzhang@whu.edu.cn.|Key Laboratory of Detection for Mycotoxins, Ministry of Agriculture, Wuhan 430062, China. zwzhang@whu.edu.cn.
authors.forename: Zhaowei
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. zhangqi01@caas.cn.|Key Laboratory of Detection for Mycotoxins, Ministry of Agriculture, Wuhan 430062, China. zhangqi01@caas.cn.|Laboratory of Risk Assessment for oilseeds Products (Wuhan), Ministry of Agriculture, Wuhan 430062, China. zhangqi01@caas.cn.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430062, China. peiwuli@oilcrops.cn.|Key Laboratory of Biology and Genetic Improvement of oil Crops, Ministry of Agriculture, Wuhan 430062, China. peiwuli@oilcrops.cn.|Key Laboratory of Detection for Mycotoxins, Ministry of Agriculture, Wuhan 430062, China. peiwuli@oilcrops.cn.|Laboratory of Risk Assessment for oilseeds Products (Wuhan), Ministry of Agriculture, Wuhan 430062, China. peiwuli@oilcrops.cn.|Quality Inspection and Test Center for oilseeds Products, Ministry of Agriculture, Wuhan 430062, China. peiwuli@oilcrops.cn.
authors.forename: Peiwu
authors.initials: P
authors.lastname: Li
mesh_terms: D000906:Antibodies / Q000276:immunology*; D052157:Aptamers, Nucleotide; D015374:Biosensing Techniques / Q000295:instrumentation; D005504:Food Analysis / Q000295:instrumentation / Q000379:methods*; D005516:Food Microbiology; D057166:High-Throughput Screening Assays / Q000295:instrumentation; D046228:Microarray Analysis; D009183:Mycotoxins / Q000032:analysis* / Q000276:immunology; D011934:Reagent Strips; D015203:Reproducibility of Results
chemical_list: D000906:Antibodies; D052157:Aptamers, Nucleotide; D009183:Mycotoxins; D011934:Reagent Strips
keywords: antibody; aptamer; mycotoxin; sensor