title: [Space-occupying lesion in the maxillary sinus].
abstract: During the preoperative diagnostics of an 80-year-old male patient prior to a planned endarterectomy, an unclear space-occupying lesion was detected in the right nasopharyngeal cavity. It proved to be a dense soft tissue space-occupying lesion of the right maxillary sinus. The histological investigations revealed a partially necrotically decomposed malignant tumor below normal respiratory mucosa free from dysplasia. This case demonstrates the difficulties in differential diagnostics, particularly involving (aberrant) expression of cytokeratin.
authors.affiliation: Institut für Pathologie, Charité-Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117, Berlin, Deutschland. philipp.lohneis@charite.de.
authors.forename: P
authors.initials: P
authors.lastname: Lohneis
authors.affiliation: Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité-Universitätsmedizin Berlin, Berlin, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Nogai
authors.affiliation: Klinik und Hochschulambulanz für Radiologie, Charité-Universitätsmedizin Berlin, Berlin, Deutschland.
authors.forename: S M
authors.initials: SM
authors.lastname: Niehues
authors.affiliation: Institut für Pathologie, Charité-Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117, Berlin, Deutschland.
authors.forename: K
authors.initials: K
authors.lastname: Jöhrens
authors.affiliation: Institut für Pathologie, Charité-Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117, Berlin, Deutschland.
authors.forename: I
authors.initials: I
authors.lastname: Anagnostopoulos
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D016893:Carotid Stenosis / Q000601:surgery; D002467:Cell Nucleus / Q000473:pathology; D003937:Diagnosis, Differential; D016894:Endarterectomy, Carotid; D006801:Humans; D007150:Immunohistochemistry; D033162:Incidental Findings; D007633:Keratins / Q000032:analysis; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D009336:Necrosis; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D007633:Keratins
keywords: Aberrant expression; Cytokeratin; Differential diagnosis; Extramedullary; Plasma cell neoplasm