title: Aggregatibacter aphrophilus misidentified as Brucella spp. in an immunocompetent patient with brain abscess.
abstract: Aggregatibacter aphrophilus rarely causes brain abscesses. Here we report a case of the brain abscess caused by Aggregatibacter aphrophilus. Cultivated gram negative coccobacilli from cerebral abscess were initially misidentified as Brucella spp. because it gave false positive agglutination with anti-Brucella sera. Definite identification was made with MALDI-TOF assay. Right to left shunt through the pulmonary arteriovenous malformation was speculated to be the underlying cause for the brain abscess. The patient was treated successfully with ampicillin-sulbactam after failing ceftriaxone treatment.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sihhiye, Ankara, Turkey.
authors.forename: Ahmet Cagkan
authors.initials: AC
authors.lastname: Inkaya
authors.affiliation: Department of Medical Microbiology, Faculty of Medicine, Sihhiye, Ankara, Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Macin
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Sihhiye, Ankara, Turkey.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Bozkurt
authors.affiliation: Department of Radiology, Section of Neuroradiology, Hacettepe University, Faculty of Medicine, Sihhiye, Ankara, Turkey.
authors.forename: Rahsan
authors.initials: R
authors.lastname: Gocmen
authors.affiliation: Department of Medical Microbiology, Faculty of Medicine, Sihhiye, Ankara, Turkey.
authors.forename: Yakut
authors.initials: Y
authors.lastname: Akyon
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Sihhiye, Ankara, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: Unal
mesh_terms: D000328:Adult; D064207:Aggregatibacter aphrophilus; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging*; D001922:Brain Abscess / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D002002:Brucella; D002006:Brucellosis / Q000175:diagnosis*; D003951:Diagnostic Errors; D004322:Drainage; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008279:Magnetic Resonance Imaging; D016871:Pasteurellaceae Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D012640:Seizures / Q000209:etiology; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D000900:Anti-Bacterial Agents
keywords: Aggregatibacter aphrophilus, brain abscess, brucella.