title: Asymmetrical dimethyl arginine in type 2 diabetic patients with coronary artery disease.
abstract: OBJECTIVE
  To compare clinical and biochemical parameters for type 2 diabetic patients having coronary artery disease with controls.
  
  
  METHODS
  The analytical, cross-sectional study was conducted at Khyber Medical College, Peshawar, Pakistan, for a period of one year between 2010 and 2011, and comprised two groups; Group A had normal controls, while Group B had type 2 diabetic patients with coronary artery disease. Clinical parameters were blood pressure and body mass index. Blood was centrifuged for blood sugar, glycosylated haemoglobin, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglyceride and asymmetrical dimethylarginine. SPSS 15 was used to analyse data.
  
  
  RESULTS
  Of the 150 subjects, there were 75(50%) each in Group A and Group B, which had the mean age of 50.8±80 years and 53.4±52 years, respectively. Both systolic and diastolic blood pressure and body mass index were raised and an elevated level of serum asymmetric dimethylarginine, fasting blood sugar, total cholesterol, triglycerides, glycosylated haemoglobin was noted among Group B patients (p<0.05). .
  
  
  CONCLUSIONS
  All clinical and biochemical parameters were found raised among diabetic patients with coronary artery disease.
authors.affiliation: Department of Biochemistry, Medical College, Khyber Medical College KMC, Peshawar, Pakistan.
authors.forename: Kalsoom
authors.initials: K
authors.lastname: Tariq
authors.affiliation: Department of Biochemistry, Medical College, Khyber Medical College KMC, Peshawar, Pakistan.
authors.forename: Mudassir Ahmad
authors.initials: MA
authors.lastname: Khan
mesh_terms: D000328:Adult; D001120:Arginine / Q000031:analogs & derivatives* / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D003324:Coronary Artery Disease / Q000097:blood* / Q000150:complications; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
chemical_list: D001120:Arginine; D001786:Blood Glucose; D006442:Glycated Hemoglobin; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides; C018524:N,N-dimethylarginine
keywords: Type 2 diabetes mellitus, Coronary artery disease, Asymmetrical dimethylarginine, Glycosylated haemoglobin.