title: Electrochemical Oxidative C-H/N-H Coupling between γ-Lactams and Anilines.
abstract: A mild method for the direct C-H/N-H coupling between γ-lactams and anilines through electrochemical oxidation has been developed. The protocol proceeded smoothly without metal catalysts at room temperature to afford γ-substituted γ-lactams in good yields. It has been revealed that the quasi-divided cell which provided high current density on the anode was crucial for this reaction.
authors.affiliation: Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, P. R. China.
authors.forename: Ming
authors.initials: M
authors.lastname: Gong
authors.affiliation: Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, P. R. China. chehjm@scut.edu.cn.
authors.forename: Jing-Mei
authors.initials: JM
authors.lastname: Huang
keywords: C−H/N−H coupling; anilines; electrochemistry; metal free; γ-lactams