title: Hemotransfusion and mechanical ventilation time are associated with intra-hospital mortality in patients with traumatic brain injury admitted to intensive care unit.
abstract: OBJECTIVE
  To identify the factors associated with the intra-hospital mortality in patients with traumatic brain injury (TBI) admitted to intensive care unit (ICU).
  
  
  METHODS
  The sample included patients with TBI admitted to the ICU consecutively in a period of one year. It was defined as variables the epidemiological characteristics, factors associated with trauma and variables arising from clinical management in the ICU.
  
  
  RESULTS
  The sample included 87 TBI patients with a mean age of 28.93 ± 12.72 years, predominantly male (88.5%). The intra-hospital mortality rate was of 33.33%. The initial univariate analysis showed a significant correlation of intra-hospital death and the following variables: the reported use of alcohol (p = 0.016), hemotransfusion during hospitalization (p = 0.036), and mechanical ventilation time (p = 0.002).
  
  
  CONCLUSIONS
  After multivariate analysis, the factors associated with intra-hospital mortality in TBI patients admitted to the intensive care unit were the administration of hemocomponents and mechanical ventilation time.
authors.affiliation: Unviersidade de São Paulo, Departamento de Neurologia, São Paulo SP, Brasil;
authors.forename: Kelson James
authors.initials: KJ
authors.lastname: Almeida
authors.affiliation: Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina PI, Brasil.
authors.forename: Ânderson Batista
authors.initials: ÂB
authors.lastname: Rodrigues
authors.affiliation: Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina PI, Brasil.
authors.forename: Luiz Euripedes Almondes Santana
authors.initials: LE
authors.lastname: Lemos
authors.affiliation: Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina PI, Brasil.
authors.forename: Marconi Cosme Soares de
authors.initials: MC
authors.lastname: Oliveira
authors.affiliation: Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina PI, Brasil.
authors.forename: Brisa Fideles
authors.initials: BF
authors.lastname: Gandara
authors.affiliation: Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina PI, Brasil.
authors.forename: Raissa da Rocha
authors.initials: Rda R
authors.lastname: Lopes
authors.affiliation: Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina PI, Brasil.
authors.forename: Daniel Rocha E Silva
authors.initials: DR
authors.lastname: Modesto
authors.affiliation: Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina PI, Brasil.
authors.forename: Irizon Klecio Pereira
authors.initials: IK
authors.lastname: Rego
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001803:Blood Transfusion; D000070642:Brain Injuries, Traumatic / Q000209:etiology / Q000401:mortality* / Q000628:therapy; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult