title: Synthesis of Barbaralones and Bullvalenes Made Easy by Gold Catalysis.
abstract: The gold(I)-catalyzed oxidative cyclization of 7-ethynyl-1,3,5-cycloheptatrienes gives 1-substituted barbaralones in a general manner, which simplifies the access to other fluxional molecules. As an example, we report the shortest syntheses of bullvalene, phenylbullvalene, and disubstituted bullvalenes, and a readily accessible route to complex cage-type structures by further gold(I)-catalyzed reactions.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007, Tarragona, Spain.
authors.forename: Sofia
authors.initials: S
authors.lastname: Ferrer
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007, Tarragona, Spain. aechavarren@iciq.es.|Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, C/ Marcel⋅li Domingo s/n, 43007, Tarragona, Spain. aechavarren@iciq.es.
authors.forename: Antonio M
authors.identifier: 0000-0001-6808-3007
authors.initials: AM
authors.lastname: Echavarren
keywords: barbaralones; bullvalenes; cyclization reactions; gold; valence tautomerism