title: Development and Differentiation of Mesenchymal Bone Marrow Cells in Porous Permeable Titanium Nickelide Implants In Vitro and In Vivo.
abstract: We studied the structure of porous permeable titanium nickelide used as the scaffold. In vitro population of the porous scaffold with multipotent mesenchymal stem bone marrow cells on days 7, 14, 21, and 28 was analyzed by scanning electron microscopy. Stage-by-stage histogenesis of the tissues formed from the bone marrow cells in the titanium nickelide scaffold in vivo is described in detail. Using mesenchymal stem cells, we demonstrated that porous permeable titanium nickelide scaffolds are unique incubators for cell cultures applicable for tissue engineering.
authors: Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University, Tomsk, Russia. kokorevov@yandex.ru.
authors: O V
authors: OV
authors: Kokorev
authors: Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University, Tomsk, Russia.
authors: V N
authors: VN
authors: Khodorenko
authors: Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University, Tomsk, Russia.
authors: A A
authors: AA
authors: Radkevich
authors: Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University, Tomsk, Russia.
authors: G Ts
authors: GTs
authors: Dambaev
authors: Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University, Tomsk, Russia.
authors: V E
authors: VE
authors: Gunter
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects; D001854:Bone Marrow Cells / Q000166:cytology* / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000187:drug effects; D051379:Mice; D009532:Nickel / Q000009:adverse effects*; D016062:Porosity; D023822:Tissue Engineering; D014025:Titanium / Q000009:adverse effects*
chemical_list: D001672:Biocompatible Materials; C040654:titanium nickelide; D009532:Nickel; D014025:Titanium
keywords: biocompatibility; biomaterial; tissue bioengineering; titanium nickelide