title: [Epidemic meningitis in 2013 in Republic of Guinea: Nesseria meningitidis W135 emergence].
abstract: A prospective study conducted from 1 January to 31 December 2013 described a meningitis epidemic in Republic of Guinea. The identification of the germs was based on Gram stain, latex agglutination and culture. During the study period, 480 suspected cases of meningitis were reported by 21 health districts. The average age was 18±8 years and 62.5% were men. The vaccination status was unknown in all patients. The largest attack rates were found in Siguiri (3.2 per 10,000), Kankan (2.6 per 10,000) and Dabola (3.9 per 10,000). The locality of Kintinian in Siguiri was the only one to cross the epidemic threshold. The identified microorganisms were Haemophilus influenzae (1 time), Pneumococcus (2 times), Neisseria meningitidis A (4 times) and W135 (10 times) with a total of 17 positive samples. All of these germs were sensitive to chloramphenicol, ceftriaxone and ciprofloxacin. The average hospital stay was 6.5±2 days. The lethality was 13.8%. This meningitis epidemic was characterized by the emergence of Neisseria meningitidis W135. The monitoring of this serogroup should be increased and future vaccination strategies must include it presence.
authors: Service des maladies infectieuses et tropicales de l'hôpital national Donka, CHU de Conakry, Conakry, République de Guinée. fatraore01@gmail.com.|Université de Conakry, Conakry, République de Guinée. fatraore01@gmail.com.
authors: F A
authors: FA
authors: Traoré
authors: Service des maladies infectieuses et tropicales de l'hôpital national Donka, CHU de Conakry, Conakry, République de Guinée.|Université de Conakry, Conakry, République de Guinée.
authors: F B
authors: FB
authors: Sako
authors: Université de Conakry, Conakry, République de Guinée.
authors: D
authors: D
authors: Sylla
authors: Service des maladies infectieuses et tropicales de l'hôpital national Donka, CHU de Conakry, Conakry, République de Guinée.
authors: D S
authors: DS
authors: Kader
authors: Service des maladies infectieuses et tropicales de l'hôpital national Donka, CHU de Conakry, Conakry, République de Guinée.
authors: M
authors: M
authors: Bangoura
authors: Médecins Sans Frontières, 8 rue Saint Sabin, 75011, Paris, France.
authors: M
authors: M
authors: Traoré
authors: Service des maladies infectieuses et tropicales de l'hôpital national Donka, CHU de Conakry, Conakry, République de Guinée.
authors: A
authors: A
authors: Keita
authors: Service des maladies infectieuses et tropicales de l'hôpital national Donka, CHU de Conakry, Conakry, République de Guinée.
authors: A
authors: A
authors: Sidibé
authors: Ministère de la Santé, Conakry, République de Guinée.
authors: S
authors: S
authors: Keita
authors: Service des maladies infectieuses et tropicales de l'hôpital national Donka, CHU de Conakry, Conakry, République de Guinée.
authors: M
authors: M
authors: Barry
authors: Université de Conakry, Conakry, République de Guinée.
authors: M
authors: M
authors: Cisse
authors: Université de Conakry, Conakry, République de Guinée.
authors: A
authors: A
authors: Touré
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000382:microbiology; D004196:Disease Outbreaks; D058872:Epidemics; D005260:Female; D016701:Guinea / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008585:Meningitis, Meningococcal / Q000453:epidemiology* / Q000382:microbiology; D038582:Neisseria meningitidis, Serogroup W-135 / Q000302:isolation & purification*; D055815:Young Adult
keywords: Dabola; Epidemic; Guinea; Kankan; Kintinian; Meningitis; Neisseria meningitidis W135; Siguiri; Sub-Saharan Africa