title: [Analysis of histoprognostic factors for the non metastatic rectal cancer in a west Algerian series of 58 cases].
abstract: BACKGROUND
  The aim of our study was to analyze histoprognostic factors in patients with non-metastatic rectal cancer operated at the division of surgery "A" in Tlemcen, west Algeria, over a period of six years.
  
  
  METHODS
  Retrospective study of 58 patients with rectal adenocarcinoma. Evaluation criterion was survival. Parameters studied were sex, age, tumor stage, tumor recurrence.
  
  
  RESULTS
  The average age was 58 years, 52% of men and 48% of women, with sex-ratio (1,08). Tumor seat was: middle rectum 41.37%, lower rectum 34.48% and upper rectum 24.13%. Concerning TNM clinical staging, patients were classified as stage I (17.65%), stage II (18.61%), stage III (53.44%) and stage IV (7.84%). Median overall survival was 40 months ±2,937 months. Survival based on tumor staging: stage III and IV had a lower 3 years survival rate (19%) versus stage I, II which had a survival rate of 75% (P = 0.000) (95%). Patients with tumor recurrences had a lower 3 years survival rate compared to those who had no tumoral recurrences (30.85% vs 64.30% P = 0.043).
  
  
  CONCLUSIONS
  In this series, univariate analysis of prognostic factors affecting survival allowed to retain only three factors influencing survival: tumor size, stage and tumor recurrences. In multivariate analysis using Cox's model only one factor was retained: tumor recurrence.
authors: Service de Chirurgie Viscérale «A», Centre Hospitalier Universitaire Tlemcen, Laboratoire de Recherche N°39, Faculté de Médecine, Tlemcen, Algérie.
authors: Smain Nabil
authors: SN
authors: Mesli
authors: Service d'Epidémiologie Centre Hospitalier Universitaire, Oran, Algérie.
authors: Derbali
authors: D
authors: Regagba
authors: Service de Chirurgie Hépatobiliaire et Greffe du Foie EHU- 1er Novembre 1954, Oran, Algérie.
authors: Anisse
authors: A
authors: Tidjane
authors: Laboratoire de Chirurgie Expérimentale N°39, Faculté de Médecine, Tlemcen, Algérie.
authors: Mokhtar
authors: M
authors: Benkalfat
authors: Service de Chirurgie Viscérale «A», Centre Hospitalier Universitaire Tlemcen, Laboratoire de Recherche N°39, Faculté de Médecine, Tlemcen, Algérie.
authors: Chakib
authors: C
authors: Abi-Ayad
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000462:Algeria; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D011379:Prognosis; D016016:Proportional Hazards Models; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies; D015996:Survival Rate
keywords: Rectal adenocarcinoma; recurrence; survival