title: Extrarenal Nephroblastoma of the Retroperitoneal Space in Children: A Case Report and Review of the Literature.
abstract: Extrarenal nephroblastoma (ERNB) is a rare disease. We report a case of ERNB in a 4-year-old boy complaining of abdominal pain and vomiting. Imaging showed a retroperitoneal mass and left hydronephrosis. The mass was completely removed by surgery. The pathologic diagnosis was ERNB with favorable histology. Postoperative chemotherapy was administered for 24 weeks with actinomycin D, vincristine, and doxorubicin. No signs of recurrence were found for the next 3 years. We consider 53 reports of ERNB and our own. Median age at diagnosis was 42 months. The most common site is the retroperitoneal space (44.4%), followed by the uterus (14.8%).
authors: Departments of *Pediatrics ‡Renal Transplant Surgery, Sapporo Hokuyu Hospital, Hokkaido §Pathological Analysis Center, GeneticLab Co. Ltd. ∥Department of Pediatric Surgery, Tenshi Hospital ¶Department of Pediatrics, Hakodate Goryoukaku Hospital †Department of Pediatrics, Teine Keijinkai Hospital, Hokkaido, Japan.
authors: Ryo
authors: R
authors: Itoshima
authors: Ryoji
authors: R
authors: Kobayashi
authors: Hirozumi
authors: H
authors: Sano
authors: Daiki
authors: D
authors: Hori
authors: Kenji
authors: K
authors: Kishimoto
authors: Daisuke
authors: D
authors: Suzuki
authors: Masayoshi
authors: M
authors: Miura
authors: Yoshitake
authors: Y
authors: Takagi
authors: Hiroshi
authors: H
authors: Yamamoto
authors: Shoji
authors: S
authors: Fujita
authors: Ryota
authors: R
authors: Honjo
authors: Kunihiko
authors: K
authors: Kobayashi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D003609:Dactinomycin / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging; D008297:Male; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D014750:Vincristine / Q000627:therapeutic use; D009396:Wilms Tumor / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D003609:Dactinomycin; D014750:Vincristine; D004317:Doxorubicin