title: Endolymphatic hydrops in patients with unilateral and bilateral Meniere's disease.
abstract: CONCLUSIONS
  All definite Meniere's disease (MD) had endolymphatic hydrops (EH) at least in the cochlea or the vestibule. Symptoms of MD may appear after formation of EH. It is assumed that the probability of immediate progression to bilateral MD from unilateral MD is very low in patients without EH on the non-affected side.
  
  
  OBJECTIVE
  To evaluate the EH on both sides in patients with unilateral and bilateral MD, and to investigate factors with progression to bilateral MD including the degree of EH, hearing level, and the duration of MD.
  
  
  METHODS
  The study included 29 patients with unilateral definite MD and 12 patients with bilateral definite MD. The endolymphatic space size was visualized by using 3-Tesla magnetic resonance imaging.
  
  
  RESULTS
  All patients with unilateral and bilateral MD had significant or mild EH at least in the cochlea or the vestibule on the affected side. On the non-affected side, EH was not observed at all in eight patients, but asymptomatic EH was observed in the cochlea in 14 patients and in the vestibule in 16 patients. There was no relationship between the EH on the non-affected side and the duration of MD.
authors: a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Kyoko
authors: K
authors: Morimoto
authors: a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Tadao
authors: T
authors: Yoshida
authors: b Department of Otorhinolaryngology , National Center for Geriatrics and Gerontology , Obu , Japan.
authors: Saiko
authors: S
authors: Sugiura
authors: a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Masahiro
authors: M
authors: Kato
authors: a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Ken
authors: K
authors: Kato
authors: a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Masaaki
authors: M
authors: Teranishi
authors: c Department of Radiology , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Shinji
authors: S
authors: Naganawa
authors: a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.|b Department of Otorhinolaryngology , National Center for Geriatrics and Gerontology , Obu , Japan.
authors: Tsutomu
authors: T
authors: Nakashima
authors: a Department of Otorhinolaryngology , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Michihiko
authors: M
authors: Sone
mesh_terms: D018450:Disease Progression; D007758:Ear, Inner / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006309:Hearing; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008575:Meniere Disease / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D008875:Middle Aged
keywords: Endolymphatic hydrops; bilateral Meniere’s disease; magnetic resonance imaging; unilateral Meniere’s disease