title: A multipurpose natural and renewable polymer in medical applications: Bacterial cellulose.
abstract: Bacterial cellulose (BC) produced by some bacteria, among them Gluconacetobacter xylinum, which secrets an abundant 3D networks fibrils, represents an interesting emerging biocompatible nanomaterial. Since its discovery BC has shown tremendous potential in a wide range of biomedical applications, such as artificial skin, artificial blood vessels and microvessels, wound dressing, among others. BC can be easily manipulated to improve its properties and/or functionalities resulting in several BC based nanocomposites. As example BC/collagen, BC/gelatin, BC/Fibroin, BC/Chitosan, etc. Thus, the aim of this review is to discuss about the applicability in biomedicine by demonstrating a variety of forms of this biopolymer highlighting in detail some qualities of bacterial cellulose. Therefore, various biomedical applications ranging from implants and scaffolds, carriers for drug delivery, wound-dressing materials, etc. that were reported until date will be presented.
authors: School of Dentistry/Unesp, São Paulo State University - Unesp, Rua Humaitá, 1680, 14801-903, Araraquara, SP, Brazil.
authors: Hélida Gomes
authors: HG
authors: de Oliveira Barud
authors: Institute of Chemistry, São Paulo State University - Unesp, CP 355, Araraquara, SP, 14801-970, Brazil.
authors: Robson Rosa
authors: RR
authors: da Silva
authors: University Center of Araraquara, UNIARA, Brazil; Institute of Chemistry, São Paulo State University - Unesp, CP 355, Araraquara, SP, 14801-970, Brazil. Electronic address: hsbarud@yahoo.com.br.
authors: Hernane
authors: H
authors: da Silva Barud
authors: Group 'Materials+Technologies', Department of Chemical and Environmental Engineering, University of the Basque Country, UPV/EHU, Plaza Europa 1, 20018 Donostia-San Sebastián, Spain.
authors: Agnieszka
authors: A
authors: Tercjak
authors: Group 'Materials+Technologies', Department of Chemical and Environmental Engineering, University of the Basque Country, UPV/EHU, Plaza Europa 1, 20018 Donostia-San Sebastián, Spain.
authors: Junkal
authors: J
authors: Gutierrez
authors: University Center of Araraquara, UNIARA, Brazil.
authors: Wilton Rogério
authors: WR
authors: Lustri
authors: School of Dentistry/Unesp, São Paulo State University - Unesp, Rua Humaitá, 1680, 14801-903, Araraquara, SP, Brazil.
authors: Osmir Batista
authors: OB
authors: de Oliveira
authors: Institute of Chemistry, São Paulo State University - Unesp, CP 355, Araraquara, SP, 14801-970, Brazil.
authors: Sidney J L
authors: SJL
authors: Ribeiro
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000627:therapeutic use; D001419:Bacteria / Q000737:chemistry*; D001458:Bandages; D001672:Biocompatible Materials / Q000737:chemistry* / Q000627:therapeutic use*; D002482:Cellulose / Q000031:analogs & derivatives / Q000737:chemistry* / Q000627:therapeutic use*; D016503:Drug Delivery Systems / Q000379:methods; D041822:Gluconacetobacter xylinus / Q000737:chemistry; D006801:Humans; D011135:Polysaccharides, Bacterial / Q000031:analogs & derivatives / Q000737:chemistry* / Q000627:therapeutic use*; D019736:Prostheses and Implants; D023822:Tissue Engineering / Q000379:methods; D054457:Tissue Scaffolds / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D011135:Polysaccharides, Bacterial; D002482:Cellulose
keywords: Bacterial cellulose; Biopolymers; Collagen (PubChem CID: 6913668); Kaolin (PubChem CID: 56841936); Nanocomposites; TiO2 (PubChem CID: 162651); Tissue engineering; Tissue scaffolds; Wound healing; celulose (PubChem CID: 71853); chitosan (PubChem CID: 71853); hyaluronan (PubChem CID: 24759); propolis (PubChem CID: 10455788); silver (PubChem CID 104755); tetracycline (PubChem CID: 54675776)