title: Melanoma burden and recent trends among non-Hispanic whites aged 15-49years, United States.
abstract: Melanoma is among the most common cancers for adolescents and young adults. Updated information on melanoma among adults <50 is needed. The objective of this study was to examine invasive melanoma in the United States among people aged 15-49years for the group at highest risk, non-Hispanic whites. In 2015, we analyzed population-based cancer registry data from the Centers for Disease Control and Prevention's National Program of Cancer Registries and the National Cancer Institute's Surveillance, Epidemiology, and End Results program to examine melanoma incidence and death rates and trends among non-Hispanic whites aged 15-49years by sex and age. We also present incidence trends with regard to thickness and site on the body. Among non-Hispanic whites aged 15-49years, rates were higher among females. Thin melanomas increased among both sexes during 1992-2006 and stabilized during 2006-2012. For the period 1992-2012, melanomas thicker than 4mm increased among males and melanomas 1.01-2.00mm thick increased among females. Melanomas were most commonly diagnosed on the trunk and lower extremity among females and on the trunk and upper extremity among males. Increases in melanoma incidence among non-Hispanic whites aged 15-49years across various thicknesses suggest that melanoma trends are not solely related to increased screening but are, in part, related to true increases. Declines in melanoma rates of about 3% a year from the mid-2000s to 2012 in the youngest age groups offer hope that melanoma incidence may decline in future generations.
authors: Epidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: Eze5@cdc.gov.
authors: Meg
authors: M
authors: Watson
authors: Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, MA, United States.
authors: Alan C
authors: AC
authors: Geller
authors: Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, United States.
authors: Margaret A
authors: MA
authors: Tucker
authors: Epidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, United States.
authors: Gery P
authors: GP
authors: Guy
authors: Departments of Dermatology and Epidemiology, Brown University, V A Medical Center, Providence, RI, United States.
authors: Martin A
authors: MA
authors: Weinstock
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D006801:Humans; D015994:Incidence; D008545:Melanoma / Q000453:epidemiology* / Q000401:mortality; D008875:Middle Aged; D012042:Registries; D012307:Risk Factors; D018426:SEER Program; D012737:Sex Factors; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000401:mortality; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data*
keywords: Adolescent and young adult; Cancer incidence; Cancer mortality; Melanoma; Trends