title: Addressing the Challenges of Pathogen Evolution on the World's Arable Crops.
abstract: Advances in genomic and molecular technologies coupled with an increasing understanding of the fine structure of many resistance and infectivity genes, have opened up a new era of hope in controlling the many plant pathogens that continue to be a major source of loss in arable crops. Some new approaches are under consideration including the use of nonhost resistance and the targeting of critical developmental constraints. However, the major thrust of these genomic and molecular approaches is to enhance the identification of resistance genes, to increase their ease of manipulation through marker and gene editing technologies and to lock a range of resistance genes together in simply manipulable resistance gene cassettes. All these approaches essentially continue a strategy that assumes the ability to construct genetic-based resistance barriers that are insurmountable to target pathogens. Here we show how the recent advances in knowledge and marker technologies can be used to generate more durable disease resistance strategies that are based on broad evolutionary principles aimed at presenting pathogens with a shifting, landscape of fluctuating directional selection.
authors: First and second authors: Fujian Key Lab of Plant Virology, Institute of Plant Virology; Fujian Agriculture and Forestry University, Fuzhou, China; first, third, and fifth authors: CSIRO Agriculture, PO Box 1600, Canberra, A.C.T. 2601, Australia; and fourth author: INRA Biostatistics and Spatial Processes, Domaine Saint-Paul AgroParc, 84914 Avignon, France.
authors: Jeremy J
authors: JJ
authors: Burdon
authors: First and second authors: Fujian Key Lab of Plant Virology, Institute of Plant Virology; Fujian Agriculture and Forestry University, Fuzhou, China; first, third, and fifth authors: CSIRO Agriculture, PO Box 1600, Canberra, A.C.T. 2601, Australia; and fourth author: INRA Biostatistics and Spatial Processes, Domaine Saint-Paul AgroParc, 84914 Avignon, France.
authors: Jiasui
authors: J
authors: Zhan
authors: First and second authors: Fujian Key Lab of Plant Virology, Institute of Plant Virology; Fujian Agriculture and Forestry University, Fuzhou, China; first, third, and fifth authors: CSIRO Agriculture, PO Box 1600, Canberra, A.C.T. 2601, Australia; and fourth author: INRA Biostatistics and Spatial Processes, Domaine Saint-Paul AgroParc, 84914 Avignon, France.
authors: Luke G
authors: LG
authors: Barrett
authors: First and second authors: Fujian Key Lab of Plant Virology, Institute of Plant Virology; Fujian Agriculture and Forestry University, Fuzhou, China; first, third, and fifth authors: CSIRO Agriculture, PO Box 1600, Canberra, A.C.T. 2601, Australia; and fourth author: INRA Biostatistics and Spatial Processes, Domaine Saint-Paul AgroParc, 84914 Avignon, France.
authors: Julien
authors: J
authors: Papaïx
authors: First and second authors: Fujian Key Lab of Plant Virology, Institute of Plant Virology; Fujian Agriculture and Forestry University, Fuzhou, China; first, third, and fifth authors: CSIRO Agriculture, PO Box 1600, Canberra, A.C.T. 2601, Australia; and fourth author: INRA Biostatistics and Spatial Processes, Domaine Saint-Paul AgroParc, 84914 Avignon, France.
authors: Peter H
authors: PH
authors: Thrall
mesh_terms: D005075:Biological Evolution; D018556:Crops, Agricultural / Q000235:genetics / Q000276:immunology*; D060467:Disease Resistance; D023281:Genomics; D010935:Plant Diseases / Q000276:immunology / Q000517:prevention & control*; D062211:Spatio-Temporal Analysis
keywords: gene deployment strategies; infectivity; qualitative resistance; quantitative resistance; varietal mixtures