title: Preconception optimization of glycaemic control in diabetes.
abstract: The prevalence of Diabetes Mellitus is increasing worldwide. In developing countries 25% of adult females with diabetes are in the reproductive age. Thus in developing countries increased number of pregnancies are complicated by diabetes. Uncontrolled diabetes in pregnancy is associated with increased risk for both mother and foetus. These risks can be minimized by good control of diabetes before and during pregnancy. Management in the preconception period is discussed in this review article. Detailed management involves general advice of lifestyle modification followed by specific details of screening for complications of diabetes. Changes in the drugs for both glycaemic control and other co-morbid conditions are discussed. The recommended insulin regimen in the preconception period and monitoring of glycaemic control by self-monitoring of blood glucose (SMBG) and HbA1C has also been highlighted.
authors: Section Head, Endocrinology, Professor of Medicine & Consultant Endocrinologist, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
authors: Najmul
authors: N
authors: Islam
mesh_terms: D001786:Blood Glucose; D015190:Blood Glucose Self-Monitoring; D003920:Diabetes Mellitus; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D006442:Glycated Hemoglobin; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D008019:Life Style; D011247:Pregnancy; D011254:Pregnancy in Diabetics
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: Preconception, Diabetes mellitus, Glycaemic control, Pregnancy.