title: Nickel-Catalyzed Ortho-Arylation of Unactivated (Hetero)aryl C-H Bonds with Arylsilanes Using a Removable Auxiliary.
abstract: Ni(II)-catalyzed ortho-arylation of aromatic and heteroaromatic carboxamides with triethoxy(aryl)silanes assisted by a removable bidentate auxiliary is reported. This transformation features a broad substrate scope, good functional group tolerance, and compatibility with heterocyclic substrates. Compared to the well-established Ni(II)-catalyzed C-H arylation with ArX or aryliodonium salts via oxidative addition, this reaction proceeded via a fluoride-promoted transmetalation.
authors: Department of Chemistry, Zhejiang University , Hangzhou 310027, China.
authors: Sheng
authors: S
authors: Zhao
authors: Department of Chemistry, Zhejiang University , Hangzhou 310027, China.
authors: Bin
authors: B
authors: Liu
authors: Department of Chemistry, Zhejiang University , Hangzhou 310027, China.
authors: Bei-Bei
authors: BB
authors: Zhan
authors: Department of Chemistry, Zhejiang University , Hangzhou 310027, China.
authors: Wei-Dong
authors: WD
authors: Zhang
authors: Department of Chemistry, Zhejiang University , Hangzhou 310027, China.
authors: Bing-Feng
authors: BF
authors: Shi