title: Rheumatoid arthritis and pseudo-vesicular skin plaques: rheumatoid neutrophilic dermatosis.
abstract: A 54 year-old woman with a 3-year history of rheumatoid arthritis (RA) consulted us because of weight loss, fever and skin eruption. On physical examination, erythematous plaques with a pseudo-vesicular appearance were seen on the back of both shoulders. Histological examination was consistent with rheumatoid neutrophilic dermatosis (RND). After 3 days of prednisone treatment, the skin eruption resolved. RND is a rare cutaneous manifestation of seropositive RA, characterized by asymptomatic, symmetrical erythematous plaques with a pseudo-vesicular appearance. Histology characteristically reveals a dense, neutrophilic infiltrate with leucocitoclasis but without other signs of vasculitis. Lesions may resolve spontaneously or with RA treatment. This case illustrates an uncommon skin manifestation of active rheumatoid arthritis.
authors: Pontificia Universidad Catolica de Chile - Santiago, Chile.
authors: Juan
authors: J
authors: Manriquez
authors: Pontificia Universidad Catolica de Chile - Santiago, Chile.
authors: Laura
authors: L
authors: Giesen
authors: Pontificia Universidad Catolica de Chile - Santiago, Chile.
authors: Constanza Del
authors: CD
authors: Puerto
authors: Pontificia Universidad Catolica de Chile - Santiago, Chile.
authors: Sergio
authors: S
authors: Gonzalez
mesh_terms: D001172:Arthritis, Rheumatoid / Q000473:pathology*; D001706:Biopsy; D004890:Erythema / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*