title: Advanced Technologies Lead iNto New Reprogramming Routes.
abstract: Two recent papers provide new insights on transcriptional dynamics and epigenetic remodeling during reprogramming of induced neurons (iNs). Treutlein et al. (2016) applied single-cell transcriptomics to identify routes and detours during early iN induction, while in this issue of Cell Stem Cell, Black et al. (2016) employed gene editing to activate endogenous loci of the reprogramming factors.
authors: Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
authors: Yang
authors: Y
authors: Zhou
authors: Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: li_qian@med.unc.edu.
authors: Li
authors: L
authors: Qian
mesh_terms: D065150:Cellular Reprogramming; D044127:Epigenesis, Genetic