title: Effects of fifth day (D5) or sixth day (D6) frozen-thawed blastocysts on neonatal outcomes.
abstract: This study aimed to compare the neonatal outcomes of transplanted fifth day (D5) or sixth day (D6) frozen-thawed blastocysts, aiming to provide guidance when choosing blastocyst recovery methods. The clinical data of 1109 patients that were performed for recovered blastocyst transplantation, as well as the data of 515 patients who had already delivered were analyzed retrospectively. The patients were divided into single- or twins-birth groups according to blastocyst formation time (D5 or D6) and the number of fetus(es). The implantation rate, clinical pregnancy rate and live birth rate of the D5 group were all significantly higher than those in the D6 group (P 0.05). In conclusion, the implantation rate, clinical pregnancy rate and live birth rate in the D5 group were all significantly higher than that in the D6 group. The birth weight at D6 was prone to be heavier no matter the birth group, and the sex ratio in the D5 group was higher than that at D6, the difference in neonatal outcomes between the two groups was not statistically significant.
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Xue
authors: X
authors: Wang
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Jingran
authors: J
authors: Zhen
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Zhengyi
authors: Z
authors: Sun
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Qi
authors: Q
authors: Yu
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Chengyan
authors: C
authors: Deng
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Yuanzheng
authors: Y
authors: Zhou
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Hanbi
authors: H
authors: Wang
authors: Reproductive Center,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100730,China.
authors: Fangfang
authors: F
authors: He
mesh_terms: D000328:Adult; D001724:Birth Weight; D001755:Blastocyst / Q000502:physiology*; D015925:Cryopreservation / Q000379:methods*; D010064:Embryo Implantation; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D059285:Pregnancy, Twin; D012189:Retrospective Studies; D012744:Sex Ratio; D014427:Twins
keywords: Birth outcomes; Blastocyst; D5; D6; Frozen–thawed blastocyst transplantation