title: FDG PET-CT for solitary pulmonary nodule and lung cancer: Literature review.
abstract: The investigation of solitary pulmonary nodule (SPN) and non-small cell lung cancer (NSCLC) has rapidly become one of the main indications for18F-fluorodeoxyglucose (FDG) positron emission tomography (PET), currently combined with computed tomography (PET-CT). In this literature review, we first attempt to clarify how PET imaging contributes to investigating SPN, in conjunction with conventional CT. We highlight the prospects of research underway to improve our understanding of SPN. In the second part of this review, we analyze the current role of PET-CT in the overall care process for lung cancer. We review the indications for which consensus has been reached, for example initial staging, as well as new indications such as radiation therapy planning or prognostic assessment.
authors: Service de médecine nucléaire, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France; Université de Paris-Diderot, INSERM U944/CNRS UMR7212, 75000 Paris, France. Electronic address: dgroheux@yahoo.fr.
authors: D
authors: D
authors: Groheux
authors: Service des maladies respiratoires, CHU de Brest, 29200 Brest, France.
authors: G
authors: G
authors: Quere
authors: Service de médecine nucléaire, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France; Service de médecine nucléaire, centre chirurgical Marie-Lannelongue, 92350 Le Plessis-Robinson, France.
authors: E
authors: E
authors: Blanc
authors: Service de médecine nucléaire, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France; Université de Paris-Diderot, INSERM U944/CNRS UMR7212, 75000 Paris, France.
authors: C
authors: C
authors: Lemarignier
authors: Service de médecine nucléaire, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France.
authors: L
authors: L
authors: Vercellino
authors: Service de radiologie, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France.
authors: C
authors: C
authors: de Margerie-Mellon
authors: Service de médecine nucléaire, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France.
authors: P
authors: P
authors: Merlet
authors: Service de médecine nucléaire, CHU de Brest, 29200 Brest, France; EA 3878, GETBO, IFR 148, Brest université, 29200 Brest, France.
authors: S
authors: S
authors: Querellou
mesh_terms: D000465:Algorithms; D055088:Early Detection of Cancer; D019788:Fluorodeoxyglucose F18; D033162:Incidental Findings; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging / Q000379:methods; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D011379:Prognosis; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: FDG; Lung cancer; PET-CT; Prognosis; Solitary pulmonary nodule