title: Protein-directed assembly of cobalt phosphate hybrid nanoflowers.
abstract: The understanding and controlling of biomimetic hybrid materials are a key objective in bio-nanotechnology, materials chemistry, and colloid science fields. Biomaterials, such as, enzyme, DNA, RNA, and proteins have become important templates for the construction of inorganic-organic hybrid nanoflowers. From this perspective, we present a simple approach to synthesize protein and metal hybrid flower-like structure using bovine serum albumin (BSA) and cobalt phosphate, and the results of our study on the formation mechanism involved. The time dependent growing stage and formation mechanism were analyzed by electron microscopes and spectroscopic techniques. The protein-directed assembly method for preparation of hybrid nanoflowers described in this work could be used to fabricate other bio-metal hybrid materials with possible applications in biosensors, bioanalytical devices, and industrial biocatalyst fields.
authors: Nano-bio Application Team, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.
authors: Kyung Hoon
authors: KH
authors: Kim
authors: Nano-bio Application Team, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.
authors: Jae-Min
authors: JM
authors: Jeong
authors: Nano-bio Application Team, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.
authors: Seok Jae
authors: SJ
authors: Lee
authors: Department of Chemical Engineering, Kangwon National University, Samcheok 25913, Republic of Korea. Electronic address: bgchoi@kangwon.ac.kr.
authors: Bong Gill
authors: BG
authors: Choi
authors: Nano-bio Application Team, National Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea. Electronic address: kglee@nnfc.re.kr.
authors: Kyoung G
authors: KG
authors: Lee
mesh_terms: D002942:Circular Dichroism; D003035:Cobalt / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D010710:Phosphates / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D010710:Phosphates; D012710:Serum Albumin, Bovine; D003035:Cobalt; C026305:cobalt sulfate
keywords: Bovine serum albumin; Cobalt phosphate; Hybrid nanoflower; Nanocomposite; Protein