title: Optic disc area in different types of glaucoma.
abstract: OBJECTIVE
  To evaluate the possible relationship of optic disc area with retina nerve fiber layer in different glaucoma subtypes.
  
  
  METHODS
  One eye each was chosen from 45 patients with ocular hypertension, 45 patients with primary open angle glaucoma, 45 patients with pseudoexfoliation glaucoma and 45 healthy controls followed in our hospital. The records of the patients were reviewed retrospectively. Optic disc area and circumpapillary retina nerve fiber layer measurements were obtained using optical coherence tomography. Central corneal thickness was measured by ultrasound pachymetry.
  
  
  RESULTS
  The median disc area in the patients with primary open angle glaucoma was significantly higher than the patients with ocular hypertension (2.19 vs 1.90 mm(2), P=0.030). The median retina nerve fiber layer was thinner in the patients with primary open angle glaucoma and pseudoexfoliation glaucoma than the patients with ocular hypertension for superior, inferior and temporal quadrants. After adjustment for age, no difference in central corneal thickness was found between the groups. Greater disc area was associated with thicker retinal nerve fiber layer for superior, inferior and nasal quadrants in the patients with primary open angle glaucoma. There was no correlation between disc area and central corneal thickness measurements of the groups.
  
  
  CONCLUSIONS
  Disc size affects the retinal nerve fiber layer thickness in eyes with primary open angle glaucoma and is a possible risk factor for glaucomatous optic nerve damage.
authors: Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara 06590, Turkey.
authors: Oya
authors: O
authors: Tekeli
authors: Department of Ophthalmology, Islahiye State Hospital, Islahiye, Gaziantep 27800, Turkey.
authors: Esra
authors: E
authors: Savku
authors: Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara 06590, Turkey.
authors: Ahmed
authors: A
authors: Abdullayev
keywords: central corneal thickness; ocular hypertension; optic disc area; primary open angle glaucoma; pseudoexfoliation glaucoma; retina nerve fiber layer