title: Proliferative and necrotizing otitis externa in a kitten: successful treatment with intralesional and topical corticosteroid therapy.
abstract: Proliferative and necrotising otitis externa (PNOE) is a very rare disease affecting the ear canals and concave pinnae of kittens. This report describes a 5-month-old cat with PNOE. Histopathological examination confirmed the diagnosis. Treatment was initiated with local injection of methylprednisolone acetate into the lesions. The cat was subsequently treated with clobetasol propionate cream, a potent topical glucocorticoid ointment. The cat showed marked improvement. While topical treatment with tacrolimus, an immunosuppressive agent, is reported to be an effective therapy, to the best of our knowledge, this is the first report to treat PNOE with local corticosteroid therapy.
authors: School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan.
authors: Yutaka
authors: Y
authors: Momota
authors: Junya
authors: J
authors: Yasuda
authors: Mitsutaka
authors: M
authors: Ikezawa
authors: Jun
authors: J
authors: Sasaki
authors: Masaaki
authors: M
authors: Katayama
authors: Kenji
authors: K
authors: Tani
authors: Masahiro
authors: M
authors: Miyabe
authors: Eri
authors: E
authors: Onozawa
authors: Daigo
authors: D
authors: Azakami
authors: Katsumi
authors: K
authors: Ishioka
authors: Toshinori
authors: T
authors: Sako
mesh_terms: D000287:Administration, Topical; D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy* / Q000473:pathology; D002415:Cats; D002990:Clobetasol / Q000627:therapeutic use*; D008297:Male; D008775:Methylprednisolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000077555:Methylprednisolone Acetate; D009336:Necrosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D010032:Otitis Externa / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
chemical_list: D000077555:Methylprednisolone Acetate; D002990:Clobetasol; D008775:Methylprednisolone