title: [Predictors of extubation failure in neurosurgical patients].
abstract: BACKGROUND
  The information regarding the factors that affect the success of extubation in neurosurgical patients is limited; thus, it is necessary to determine the prevalence, and the associated factors, of extubation failure in neurosurgical patients.
  
  
  METHODS
  It was performed a prospective, longitudinal, observational and comparative study in neurosurgical patients with criteria for extubation. In those who the number of endotracheal aspirations had failed 24 hours before extubation, it was analyzed the presence of cough reflex, length of stay and mechanical ventilation days.
  
  
  RESULTS
  70 patients were included in the study, of whom 11.4 % patients failed extubation and the associated factors were performing 6 events or more of endotracheal tube suction 24 hours prior to weaning (relative risk [RR] = 1.88, 95 % confidence interval [CI] = 1.14-3.09, p 0.01), 7 days of mechanical ventilation (RR = 1.31, 95 % CI = 1.08-1.57, p 0.005) and a length of hospital stay of 7.5 days (RR = 1.24, 95 % CI = 1.05-1.47, p 0.01).
  
  
  CONCLUSIONS
  Performing 6 or more endotracheal tube suction events during the 24 hours before extubation is a risk factor for extubation failure in neurosurgical patients.
authors: Unidad de Cuidados Intensivos, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. marco.leong@imss.gob.mx.
authors: Marco Antonio
authors: MA
authors: León-Gutiérrez
authors: Janet
authors: J
authors: Tanus-Hajj
authors: Luis Alejandro
authors: LA
authors: Sánchez-Hurtado
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D060666:Airway Extubation / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D011446:Prospective Studies; D012121:Respiration, Artificial / Q000706:statistics & numerical data*; D012307:Risk Factors; D013396:Suction / Q000009:adverse effects
keywords: Airway extubation; Mechanical ventilation; Neurosurgical procedures