title: Efficacy of treatments with toltrazuril 7.5% and lasalocid sodium in sheep naturally infected with Eimeria spp.
abstract: The objective of this study was to evaluate the efficacy of an experimental formulation of toltrazuril 7.5% + Trimix™ on a naturally acquired infection of Eimeria spp. in suckling lambs kept on pasture and, in another trial, evaluate the comparative efficacy between lasalocid and toltrazuril 7.5% + Trimix™ in newly weaned sheep under feedlot conditions that had been naturally infected with Eimeria spp. In the first experiment, 30 suckling lambs were divided into two groups: A - treated with toltrazuril 7.5% + Trimix™ and B- control. In experiment 2, 30 weaned sheep were divided into three groups: I - treated with toltrazuril 7.5% + Trimix™, II - treated with lasalocid and III - control. Treatment group A showed an efficacy of 90, 99.4 and 87.3% on days 5, 10 and 20, respectively. Treatment group I had an efficacy of 98.2, 92.6 and 94.5%, while group II had an efficacy of 72.7, 81.6 and 95.9% on days 7, 21 and 42, respectively. Eight Eimeria species were identified; E. ovinoidalis was the most common. Treatment with the toltrazuril 7.5% +Trimix ™ formulation was effective against Eimeria spp. in suckling lambs in field conditions and lambs weaned in under feedlot conditions.
authors: Laboratório de Doenças Parasitárias, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Santa Maria - UFSM, Santa Maria, RS, Brasil.
authors: Fernando de Souza
authors: Fde S
authors: Rodrigues
authors: Laboratório de Parasitologia Animal, Centro de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso do Sul - UFMS, Campo Grande, MS, Brasil.
authors: Luiz Eduardo Roland
authors: LE
authors: Tavares
authors: Laboratório de Parasitologia Animal, Centro de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso do Sul - UFMS, Campo Grande, MS, Brasil.
authors: Fernando
authors: F
authors: Paiva
mesh_terms: D000818:Animals; D000833:Animals, Suckling; D003048:Coccidiosis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D003049:Coccidiostats / Q000627:therapeutic use*; D004539:Eimeria; D005243:Feces / Q000469:parasitology; D007832:Lasalocid / Q000627:therapeutic use*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000469:parasitology; D014227:Triazines / Q000627:therapeutic use*
chemical_list: D003049:Coccidiostats; D014227:Triazines; C036670:toltrazuril; D007832:Lasalocid