title: Thrombectomy and Catheter-Directed Thrombolysis Combined With Antithrombin Concentrate for Treatment of Antithrombin Deficiency Complicated by Acute Deep Vein Thrombosis That Is Refractory to Anticoagulation.
abstract: A 22-year-old male was admitted to our hospital with deep vein thrombosis that was complicated by antithrombin deficiency. This deficiency was refractory to anticoagulation therapy. Although catheter-directed thrombolysis could not reperfuse the total occlusion in the left deep vein, a combination of thrombectomy, catheter-directed thrombolysis, and antithrombin concentrate treatment was able to dissolve the clots and ameliorate the blood flow into the left deep vein. Antithrombin concentrate administration would be effective in the treatment of antithrombin deficiency with medical refractory deep vein thrombosis.
authors: Division of Cardiology, Department of Medicine II, Kansai Medical University.
authors: Hirofumi
authors: H
authors: Maeba
authors: Takeshi
authors: T
authors: Seno
authors: Ichiro
authors: I
authors: Shiojima
mesh_terms: D000208:Acute Disease; D020152:Antithrombin III Deficiency / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D017131:Thrombectomy; D015912:Thrombolytic Therapy; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D055815:Young Adult
chemical_list: D005343:Fibrinolytic Agents