title: Role of pancreatic duct cell in beta cell neogenesis: A mini review study.
abstract: Today diabetes mellitus is known as main threatening for health society. Beta cells have pivotal role in energy homeostasis by balance in blood glucose. Proliferation and neogenesis are two factors for preservation of beta cell mass but these have lower rate during adulthood rather than neonatal. Beta cell destruction occurs during diabetes that leads to hyperglycemia. Continues production of beta cell is a therapeutic strategy to keep normal blood glucose and pancreatic duct cell can be one of the sources of new beta cells. Here, we reviewed the role of pancreatic duct cell in production of beta cell based on a chronological order of conducted studies.
authors: Department of Pharmacology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Mahsa
authors: M
authors: Zare
authors: Department of Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors: Shahdokht
authors: S
authors: Rastegar
authors: Department of Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors: Esmaeel
authors: E
authors: Ebrahimi
authors: Department of Biochemistry, Taft University of Payame-Noor, Yazd, Iran.
authors: Azade
authors: A
authors: Roohipoor
authors: Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Hyperlipidemia Research Center, Department of Laboratory Sciences, School of Paramedical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: saeed.shirali@gmail.com.
authors: Saeed
authors: S
authors: Shirali
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D006801:Humans; D050417:Insulin-Secreting Cells / Q000166:cytology*; D010183:Pancreatic Ducts / Q000166:cytology / Q000502:physiology*
keywords: Beta cell; Diabetes; Hyperglycemia; Pancreatic duct cell