title: Multi-reassortant G3P[3] group A rotavirus in a horseshoe bat in Zambia.
abstract: Group A rotavirus is a major cause of diarrhoea in humans, especially in young children. Bats also harbour group A rotaviruses, but the genetic backgrounds of bat rotavirus strains are usually distinct from those of human rotavirus strains. We identified a new strain of group A rotavirus in the intestinal contents of a horseshoe bat in Zambia. Whole genome sequencing revealed that the identified virus, named RVA/Bat-wt/ZMB/LUS12-14/2012/G3P[3], possessed the genotype constellation G3-P[3]-I3-R2-C2-M3-A9-N2-T3-E2-H3. Several genome segments of LUS12-14 were highly similar to those of group A rotaviruses identified from humans, cows and antelopes, indicating interspecies transmission of rotaviruses between bats and other mammals with possible multiple genomic reassortment events.
authors: Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.
authors: Michihito
authors: M
authors: Sasaki
authors: Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.
authors: Yasuko
authors: Y
authors: Orba
authors: Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.
authors: Satoko
authors: S
authors: Sasaki
authors: Division of Bioinformatics, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.
authors: Gabriel
authors: G
authors: Gonzalez
authors: Hokudai Center for Zoonosis Control in Zambia, PO Box 32379, Lusaka, Zambia.
authors: Akihiro
authors: A
authors: Ishii
authors: Department of Paraclinical Studies, School of Veterinary and Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
authors: Bernard M
authors: BM
authors: Hang'ombe
authors: Department of Disease Control, School of Veterinary and Medicine, University of Zambia, PO Box 32379, Lusaka, Zambia.
authors: Aaron S
authors: AS
authors: Mweene
authors: Division of Bioinformatics, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.|Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.
authors: Kimihito
authors: K
authors: Ito
authors: Global Virus Network, Baltimore, MD 21201, USA.|Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.|Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, N20, W10, Kita-ku, Sapporo 001-0020, Japan.
authors: Hirofumi
authors: H
authors: Sawa
mesh_terms: D000818:Animals; D002685:Chiroptera / Q000821:virology*; D016679:Genome, Viral; D005838:Genotype; D006801:Humans; D010802:Phylogeny; D016865:Reassortant Viruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D012400:Rotavirus Infections / Q000662:veterinary* / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics; D015024:Zambia
chemical_list: D014764:Viral Proteins