title: Pulmonary Arterial Hypertension Associated with Congenital Portosystemic Shunts Treated with Transcatheter Embolization and Pulmonary Vasodilators.
abstract: Cardiopulmonary abnormalities are often present in patients with liver diseases. We herein report a case of congenital portosystemic shunts complicated by hepatopulmonary syndrome (HPS) and portopulmonary hypertension (PoPH). A 57-year-old woman complained of dyspnea and was subsequently diagnosed with HPS and PoPH caused by congenital portosystemic shunts. Although shunt closure by transcatheter embolization was successfully performed, her dyspnea worsened and pulmonary artery pressure and pulmonary vascular resistance elevated. Conventional vasodilator therapy was started, resulting in an improvement of pulmonary hypertension (PH). In some patients with congenital portosystemic shunts, shunt closure could exacerbate PH, and vasodilator therapy may be effective.
authors: Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
authors: Haruka
authors: H
authors: Sato
authors: Masanobu
authors: M
authors: Miura
authors: Nobuhiro
authors: N
authors: Yaoita
authors: Saori
authors: S
authors: Yamamoto
authors: Shunsuke
authors: S
authors: Tatebe
authors: Tatsuo
authors: T
authors: Aoki
authors: Kimio
authors: K
authors: Satoh
authors: Hideki
authors: H
authors: Ota
authors: Kei
authors: K
authors: Takase
authors: Koichiro
authors: K
authors: Sugimura
authors: Hiroaki
authors: H
authors: Shimokawa
mesh_terms: D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D020065:Hepatopulmonary Syndrome / Q000209:etiology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy*; D008875:Middle Aged; D054079:Vascular Malformations / Q000150:complications*; D014655:Vascular Resistance; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents