title: Primary Total Knee Arthroplasty After Solid Organ Transplant: Survivorship and Complications.
abstract: Clinical outcomes remain largely unknown beyond perioperative and short-term follow-up of solid organ transplant (SOT) patients undergoing total knee arthroplasty (TKA).
  
  
  
  Patient mortality, implant survivorship, and complications of 96 TKAs (76 patients) after SOT were retrospectively reviewed through an internal joint registry. Mean age at index arthroplasty was 66 years, and mean follow-up was 4 years.
  
  
  
  Overall mortality rates at 1 year, 2 years, and 5 years from TKA were 2.6%, 7.9%, and 13.2%, respectively, and combined SOT patient survivorship was 92% at 2 years and 82% at 5 years. Implant survivorship free of any component revision or implant removal was 98% at 2 years and 93% at 5 years. There was a high rate of perioperative complications (12.5%), including periprosthetic fractures (5.2%) and deep periprosthetic infection (3.2%).
  
  
  
  TKA does not appear to have any effect on SOT patient survivorship following the procedure. However, SOT patients may have a higher risk of perioperative complications and a lower implant survivorship than the general population of TKA patients at midterm follow-up.
authors: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Cameron K
authors: CK
authors: Ledford
authors: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Brian P
authors: BP
authors: Chalmers
authors: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Joseph M
authors: JM
authors: Statz
authors: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Kevin I
authors: KI
authors: Perry
authors: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Tad M
authors: TM
authors: Mabry
authors: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Arlen D
authors: AD
authors: Hanssen
authors: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors: Matthew P
authors: MP
authors: Abdel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation / Q000009:adverse effects*; D057068:Periprosthetic Fractures / Q000209:etiology; D012042:Registries; D012086:Reoperation; D012189:Retrospective Studies; D000073859:Survivorship; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: complications; mortality; primary total knee arthroplasty; solid organ transplant; survivorship