title: Smartphone Analytics: Mobilizing the Lab into the Cloud for Omic-Scale Analyses.
abstract: Active data screening is an integral part of many scientific activities, and mobile technologies have greatly facilitated this process by minimizing the reliance on large hardware instrumentation. In order to meet with the increasingly growing field of metabolomics and heavy workload of data processing, we designed the first remote metabolomic data screening platform for mobile devices. Two mobile applications (apps), XCMS Mobile and METLIN Mobile, facilitate access to XCMS and METLIN, which are the most important components in the computer-based XCMS Online platforms. These mobile apps allow for the visualization and analysis of metabolic data throughout the entire analytical process. Specifically, XCMS Mobile and METLIN Mobile provide the capabilities for remote monitoring of data processing, real time notifications for the data processing, visualization and interactive analysis of processed data (e.g., cloud plots, principle component analysis, box-plots, extracted ion chromatograms, and hierarchical cluster analysis), and database searching for metabolite identification. These apps, available on Apple iOS and Google Android operating systems, allow for the migration of metabolomic research onto mobile devices for better accessibility beyond direct instrument operation. The utility of XCMS Mobile and METLIN Mobile functionalities was developed and is demonstrated here through the metabolomic LC-MS analyses of stem cells, colon cancer, aging, and bacterial metabolism.
authors: J Rafael
authors: JR
authors: Montenegro-Burke
authors: Thiery
authors: T
authors: Phommavongsay
authors: Aries E
authors: AE
authors: Aisporna
authors: Tao
authors: T
authors: Huan
authors: Duane
authors: D
authors: Rinehart
authors: Erica
authors: E
authors: Forsberg
authors: Department of Biochemistry and Molecular Biology, University of Georgia , Athens, Georgia 30602, United States.
authors: Farris L
authors: FL
authors: Poole
authors: Department of Biochemistry and Molecular Biology, University of Georgia , Athens, Georgia 30602, United States.
authors: Michael P
authors: MP
authors: Thorgersen
authors: Department of Biochemistry and Molecular Biology, University of Georgia , Athens, Georgia 30602, United States.
authors: Michael W W
authors: MW
authors: Adams
authors: Department of Microbiology and Immunology and Center for Biofilm Engineering, Montana State University , 109 Lewis Hall, Bozeman, Montana 59717, United States.
authors: Gregory
authors: G
authors: Krantz
authors: Department of Microbiology and Immunology and Center for Biofilm Engineering, Montana State University , 109 Lewis Hall, Bozeman, Montana 59717, United States.
authors: Matthew W
authors: MW
authors: Fields
authors: Life Sciences Division, Lawrence Berkeley National Laboratory , 1 Cyclotron Road, Berkeley, California 94720, United States.
authors: Trent R
authors: TR
authors: Northen
authors: Departments of Metabolism and Aging, The Scripps Research Institute-Florida , Jupiter, Florida 33458, United States.
authors: Paul D
authors: PD
authors: Robbins
authors: Departments of Metabolism and Aging, The Scripps Research Institute-Florida , Jupiter, Florida 33458, United States.
authors: Laura J
authors: LJ
authors: Niedernhofer
authors: Luke
authors: L
authors: Lairson
authors: H Paul
authors: HP
authors: Benton
authors: Gary
authors: G
authors: Siuzdak
mesh_terms: D002853:Chromatography, Liquid; D003627:Data Interpretation, Statistical; D006801:Humans; D020407:Internet; D013058:Mass Spectrometry; D055432:Metabolomics; D063731:Mobile Applications; D025341:Principal Component Analysis; D000068997:Smartphone