title: Performance of ultrasound fetal weight estimation in twins.
abstract: BACKGROUND
  Ultrasonography is an essential tool in the management of twin pregnancies. Fetal weight estimation is useful to anticipate neonatal care in case of weight restriction or growth discordance.
  
  
  OBJECTIVE
  To assess the accuracy of estimated fetal weight (EFW) in twins and to assess the accuracy of sonographic examination to predict birth weight discordance (BWD) and small birth weight (SBW).    Methods : This was  a longitudinal prospective study over a period of one year. We have included 50 twin pregnancies with a first trimester ultrasound calculated term and specified chorionicity. An ultrasound EFW was scheduled for all patients within an interval of 4 days before delivery. We calculated the differences between EFW and BW in terms of absolute difference and percentage error. We studied the correlation and the agreement between EFW and BW. Finally we calculated the sensitivity, the specificity, PPV and NPV of ultrasound in the diagnosis of BWD and SBW.
  
  
  RESULTS
  Absolute differences between BWF and BW were similar for the two twins. The relative difference was 7.7% [0-32] for T1 and 8.2% [0-27] for T2. The margin of error was greater than 10% in 38% of the cases for T1 and in 34% of cases for T2. Furthermore, correlation coefficients R1 and R2 for T1 and T2 were close to 1; R 1 =0.87 and  R 2 = 0.89. Linear regression analysis allowed us to calculate the birth weight based on the estimated weight and this according to the following equations: For the first twin BW T1 = 0.846 * EFW 415,57+ T1 For the second twin BW T2 = 65.68 + 0.963 * EFW T2 in 34% of cases for T2. Chorionicity, presentation and gestational age did not affect the estimations. Ultrasonography in the diagnosis of SBW had a sensitivity of 90.32%, a specificity of 76.82%, a (PPV) of 80% and a (VPN) of 87%. The performance of ultrasound in the diagnosis of BWD varied according to the adopted threshold.
  
  
  CONCLUSIONS
  Ultrasound is an effective examination to estimate twins weight. Regarding prenatal diagnosis of birth weight discordance, the relevance of this examination increases with the adopted threshold.
authors: Kaouther
authors: K
authors: Dimassi
authors: Abir
authors: A
authors: Karoui
authors: Amel
authors: A
authors: Triki
authors: Mohamed Faouzi
authors: MF
authors: Gara
mesh_terms: D000328:Adult; D001724:Birth Weight; D005260:Female; D020567:Fetal Weight; D006801:Humans; D016014:Linear Models; D008137:Longitudinal Studies; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D059285:Pregnancy, Twin; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014427:Twins; D016216:Ultrasonography, Prenatal