title: Nesfatin-1: current status as a peripheral hormone and future prospects.
abstract: This review summarizes current data focusing on the peripheral effects of NUCB2/nesfatin-1 including the regulation of food intake, glucose homeostasis, lipid metabolism, cardiovascular effects and reproductive functions as well as its possible involvement in psychological disorders. Additionally, we will highlight gaps in knowledge in order to stimulate further research. Lastly, we will give an outlook on potential therapeutic implications of this pleiotropic peptide.
authors: Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors: Philip
authors: P
authors: Prinz
authors: Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany. Electronic address: andreas.stengel@charite.de.
authors: Andreas
authors: A
authors: Stengel
mesh_terms: D000818:Animals; D002135:Calcium-Binding Proteins / Q000378:metabolism*; D002319:Cardiovascular System / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism*; D004435:Eating / Q000502:physiology*; D005947:Glucose / Q000378:metabolism*; D006706:Homeostasis; D006801:Humans; D050356:Lipid Metabolism / Q000502:physiology; D001523:Mental Disorders / Q000503:physiopathology; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D000080866:Nucleobindins; D012098:Reproduction / Q000502:physiology
chemical_list: D002135:Calcium-Binding Proteins; D004268:DNA-Binding Proteins; C000630650:NUCB2 protein, human; D009419:Nerve Tissue Proteins; D000080866:Nucleobindins; D005947:Glucose