title: Release of monomers from orthodontic adhesives.
abstract: BACKGROUND
  Most composite resins release both bisphenol A (BPA), which disrupts the endocrine balance, and triethylene glycol dimethacrylate (TEGDMA), which has high risks for human health: eg, allergies and cytotoxicity. The aim of this study was to characterize monomers released from orthodontic adhesives.
  
  
  METHODS
  We studied samples of orthodontic adhesives by associating 2 techniques: gas phase chromatography and mass spectrometry.
  
  
  RESULTS
  The in-vitro analysis detected significant quantities of BPA, TEGDMA, and other monomers in orthodontic adhesives used in daily practice: Transbond XT, Transbond Supreme LV (both, 3M Unitek, Monrovia, Calif), Blugloo (Ormco, Orange, Calif), and MonoLok 2 (Rocky Mountain Orthodontics, Denver, Colo).
  
  
  CONCLUSIONS
  Clinicians should consider that orthodontic adhesives contain BPA, an endocrine disruptor; TEGDMA, an allergic and a cytotoxic compound; and carcinogenic genotoxic compounds. These molecules are not mentioned in the material safety data sheets. Manufacturers should declare all components of dental composites to identify these substances that may result in allergic or undesirable side effects for patients and dental staff.
authors: Postgraduate student, Oral and Dental Health Polyclinic, Faculty of Dentistry, Army Medical Center, Ouagadougou, Burkina Faso.
authors: Raoul
authors: R
authors: Bationo
authors: Associate professor, Department of Odontology, Faculty of Dental Surgery, University of Nantes, Nantes, France. Electronic address: fabienne.jordana@univ-nantes.fr.
authors: Fabienne
authors: F
authors: Jordana
authors: Professor, Dentistry and Oral Health Center, Pellegrin Hospital, Faculty of Dentistry, University of Bordeaux, Bordeaux, France.
authors: Marie-José
authors: MJ
authors: Boileau
authors: Associate professor, Dentistry and Oral Health Center, Pellegrin Hospital, Faculty of Dentistry, University of Bordeaux, Bordeaux, France.
authors: Jacques
authors: J
authors: Colat-Parros
mesh_terms: D000293:Adolescent; D001559:Benzhydryl Compounds / Q000009:adverse effects / Q000032:analysis*; D017438:Bisphenol A-Glycidyl Methacrylate / Q000009:adverse effects / Q000032:analysis* / Q000737:chemistry; D002648:Child; D003738:Dental Cements / Q000009:adverse effects / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008422:Materials Testing; D010636:Phenols / Q000009:adverse effects / Q000032:analysis*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D017438:Bisphenol A-Glycidyl Methacrylate; D003738:Dental Cements; D010636:Phenols; C065742:Transbond; C006780:bisphenol A; D000098826:Bisphenol A Compounds