title: Health disparities in infants with hypertrophic pyloric stenosis.
abstract: BACKGROUND
  This study investigates whether health disparities exist in infants with hypertrophic pyloric stenosis (HPS), to identify factors affecting definitive treatment, and if more morbidity occurs.
  
  
  METHODS
  A 6-year retrospective analysis was performed on infants with HPS. Analysis of variance was used to evaluate the impact of socioeconomic factors on disease severity and hospitalization. General linear models were used to assess the impact of risk factors on the outcomes.
  
  
  RESULTS
  There were a total of 584 infants. African-American's had lower serum chloride (P < .001), higher bicarbonate (P = .001), and sodium levels (P = .006), adding to longer hospitalization than whites (P = .03). Uninsured infants had lower sodium and chloride (P < .001) and higher bicarbonate (P < .001), resulting in a longer time to operation (P = .05) than privately insured infants. In multivariable analyses, African-American's were associated with chloride (P = .002) and higher bicarbonate (P = .009), and uninsured status remained significantly associated with all electrolyte abnormalities.
  
  
  CONCLUSIONS
  African-American and poorly insured infants with HPS had greater risk of metabolic derangements. This required more time to correct dehydration and electrolytes, adding to longer hospitalizations.
authors: Departments of Surgery and Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA. Electronic address: afeliz@uthsc.edu.
authors: Alexander
authors: A
authors: Feliz
authors: Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA.
authors: Janette L
authors: JL
authors: Holub
authors: Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA.
authors: Nima
authors: N
authors: Azarakhsh
authors: Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA.
authors: Marielena
authors: M
authors: Bachier-Rodriguez
authors: Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA.
authors: Kate B
authors: KB
authors: Savoie
mesh_terms: D001741:Black or African American; D015331:Cohort Studies; D005260:Female; D054624:Health Status Disparities; D006630:Hispanic or Latino; D006801:Humans; D007223:Infant; D008297:Male; D015999:Multivariate Analysis; D046248:Pyloric Stenosis, Hypertrophic / Q000097:blood / Q000453:epidemiology* / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D014481:United States / Q000453:epidemiology; D044465:White People
keywords: Ethnicity; Health disparities; Hypertrophic pyloric stenosis; Race; Socioeconomic status