title: Cutaneous Tuberculosis Occurring After a Skin Cut in a Child.
abstract: BACKGROUND
  Tuberculosis is a common problem in Turkey, and cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis. Herein, the authors describe a case of cutaneous tuberculosis (lupus vulgaris) occurring after contact with a sheep.
  
  
  METHODS
  A 15-year-old boy was admitted to Marmara University School of Medicine Pendik Training and Research Hospital (Istanbul, Turkey) with delayed wound healing on the left index finger and left axillary lymphadenopathy. His medical history was unremarkable except for a wound incurred when he slaughtered a sheep 3 months before. One month after this injury, the patient developed enlargement of the left axillary lymph node on the side of the wounded extremity, and the wound turned a dark black color. The biopsy specimens obtained from the wounded skin and lymph nodes showed granulomatous reaction, but acid-fast bacilli (AFB) could not be shown with Ehrlich-Ziehl Neelsen staining. The patient tested positive in an interferon-gamma release assay. Computerized tomography scans of the thorax were normal, and early morning gastric lavage specimen was negative for AFB. The wound and axillary lymphadenopathy disappeared after institution of anti-tuberculosis therapy.
  
  
  CONCLUSIONS
  Tuberculosis infection must be considered in chronic skin lesions with granulomatous reaction occurring in countries with high prevalence of tuberculosis.
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Gulsen
authors: G
authors: Akkoc
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Eda
authors: E
authors: Kepenekli Kadayifci
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Ayse
authors: A
authors: Karaaslan
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Serkan
authors: S
authors: Atici
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Nurhayat
authors: N
authors: Yakut
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Sevilya
authors: S
authors: Ocal Demir
authors: Department of Pathology, Marmara University School of Medicine.
authors: Gamze
authors: G
authors: Akbas
authors: Department of Pathology, Marmara University School of Medicine.
authors: Leyla
authors: L
authors: Zeliha Cinel
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Ahmet
authors: A
authors: Soysal
authors: Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, Istanbul, Turkey.
authors: Mustafa
authors: M
authors: Bakir
mesh_terms: D000003:Abattoirs; D000293:Adolescent; D000818:Animals; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001365:Axilla / Q000382:microbiology / Q000473:pathology*; D004977:Ethambutol; D005383:Finger Injuries / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D007538:Isoniazid; D008177:Lupus Vulgaris / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D000072281:Lymphadenopathy / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D009784:Occupational Diseases / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D011718:Pyrazinamide; D012293:Rifampin; D012756:Sheep; D016896:Treatment Outcome; D014421:Turkey; D014945:Wound Healing
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin