title: Postural tachycardia syndrome (POTS) with anti-NMDA receptor antibodies after human papillomavirus vaccination.
abstract: We describe a young woman who developed POTS with positive serum anti-NMDA receptor antibodies and no evidence of encephalitis after vaccination with HPV vaccine, Cervarix. Her symptoms improved significantly with immunomodulatory therapy and re-occurred after immunomodulatory therapy was stopped, suggesting an autoimmune etiology of POTS after vaccination.
authors: Department of Neurology, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, 14203, USA. sb25@buffalo.edu.
authors: Svetlana
authors: S
authors: Blitshteyn
authors: Department of Psychology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
authors: Jill
authors: J
authors: Brook
mesh_terms: D000293:Adolescent; D000906:Antibodies / Q000097:blood*; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D053918:Papillomavirus Vaccines / Q000009:adverse effects*; D010956:Plasmapheresis; D054972:Postural Orthostatic Tachycardia Syndrome / Q000097:blood / Q000139:chemically induced* / Q000276:immunology / Q000628:therapy; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology*; D014611:Vaccination / Q000009:adverse effects
chemical_list: D000906:Antibodies; D007155:Immunologic Factors; D053918:Papillomavirus Vaccines; D016194:Receptors, N-Methyl-D-Aspartate; C510352:human papillomavirus vaccine, L1 type 16, 18
keywords: Anti-NMDA receptor antibodies; Human papillomavirus vaccination; Orthostatic intolerance; Plasmapheresis; Postural tachycardia syndrome