title: [Per partum acidosis: Interest and feasibility of cerebral Doppler during labor].
abstract: OBJECTIVE
  To evaluate feasibility and interest of fetal cerebral Doppler during labor and the link with fetal pH to predict perinatal fetal asphyxia.
  
  
  METHODS
  Our prospective study in a university perinatal center, included patients during labor. There were no risk factors during pregnancy and patients were included after 37 weeks of pregnancy. For each patient an ultrasound with cerebral Doppler was done concomitant to a fetal scalp blood sample. We collected maternal and fetal characteristics as well as cervix dilatation, fetal heart rate analysis and fetal presentation.
  
  
  RESULTS
  Among 49 patients included over a period of 4 months, cerebral Doppler failed in 7 cases (11%). Majority of failure occurred at 10cm of dilatation (P=0.007, OR=14.1 [1.483; 709.1275]). Others factors like: maternal age, body mass index, parity, history of C-Section were not associated with higher rate of failure. We did not found either significant correlation between cerebral fetal Doppler and pH on fetal scalp blood sample (r=0.15) nor pH at cord blood sample (r=0.13). No threshold of cerebral Doppler is significant for fetal asphyxia prediction.
  
  
  CONCLUSIONS
  Fetal cerebral Doppler is feasible during labor with a low rate of failure but not a good exam to predict fetal acidosis and asphyxia.
authors: Maternité Port-Royal, groupe hospitalier Broca-Cochin-Hôtel Dieu, 53, avenue de l'Observatoire, 75014 Paris, France. Electronic address: barrois.mathilde@gmail.com.
authors: M
authors: M
authors: Barrois
authors: Maternité Port-Royal, groupe hospitalier Broca-Cochin-Hôtel Dieu, 53, avenue de l'Observatoire, 75014 Paris, France.
authors: M
authors: M
authors: Chartier
authors: Maternité Port-Royal, groupe hospitalier Broca-Cochin-Hôtel Dieu, 53, avenue de l'Observatoire, 75014 Paris, France; PRES Sorbonne Paris Cité, Université Paris Descartes, 75013 Paris, France; DHU risques et grossesse, 75014 Paris, France; PremUP foundation, 75014 Paris, France; Inserm, UMR-S 1139, physiopathologie et pharmacotoxicologie placentaire humaine, 75006 Paris, France.
authors: E
authors: E
authors: Lecarpentier
authors: Maternité Port-Royal, groupe hospitalier Broca-Cochin-Hôtel Dieu, 53, avenue de l'Observatoire, 75014 Paris, France; DHU risques et grossesse, 75014 Paris, France; Inserm, U-1153, 75004 Paris, France.
authors: F
authors: F
authors: Goffinet
authors: Maternité Port-Royal, groupe hospitalier Broca-Cochin-Hôtel Dieu, 53, avenue de l'Observatoire, 75014 Paris, France; PRES Sorbonne Paris Cité, Université Paris Descartes, 75013 Paris, France; DHU risques et grossesse, 75014 Paris, France; PremUP foundation, 75014 Paris, France; Inserm, UMR-S 1139, physiopathologie et pharmacotoxicologie placentaire humaine, 75006 Paris, France.
authors: V
authors: V
authors: Tsatsaris
mesh_terms: D000138:Acidosis / Q000175:diagnosis*; D001238:Asphyxia Neonatorum / Q000175:diagnosis*; D001921:Brain / Q000000981:diagnostic imaging* / Q000196:embryology; D005240:Feasibility Studies; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005311:Fetal Hypoxia; D006340:Heart Rate, Fetal; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007746:Labor Presentation; D007743:Labor, Obstetric; D011247:Pregnancy; D011446:Prospective Studies; D012535:Scalp / Q000098:blood supply / Q000196:embryology; D016216:Ultrasonography, Prenatal
keywords: Acidose néonatale; Cerebral Doppler; Doppler cérébral; Fetal acidosis; Labor; PH au scalp; Scalp pH; Travail