title: Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine PET imaging for the detection of checkpoint inhibitor-related pseudoprogression in melanoma brain metastases.
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Sied
authors: S
authors: Kebir
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Laurèl
authors: L
authors: Rauschenbach
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Norbert
authors: N
authors: Galldiks
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Max
authors: M
authors: Schlaak
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Elke
authors: E
authors: Hattingen
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Jennifer
authors: J
authors: Landsberg
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Ralph A
authors: RA
authors: Bundschuh
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Karl-Josef
authors: KJ
authors: Langen
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Björn
authors: B
authors: Scheffler
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.).
authors: Ulrich
authors: U
authors: Herrlinger
authors: Division of Clinical Neurooncology, Department of Neurology, University of Bonn Medical Center, Bonn, Germany (S.K., M.G., U.H.); Stem Cell Pathologies Group, Institute of Reconstructive Neurobiology, Bonn, Germany (S.K., L.R, B.S., M.G.); Center of Integrated Oncology (CIO), Universities of Cologne and Bonn, Germany (S.K., N.G., M.S., U.H., M.G.); Department of Neurology, University of Cologne, Cologne, Germany (N.G.), Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany (N.G., K-J.L.); Department of Dermatology, University of Cologne, Cologne, Germany (M.S.); Neuroradiology, Department of Radiology, University of Bonn Medical Center, Bonn, Germany (E.H.); Laboratory of Experimental Dermatology, Department of Dermatology and Allergy, University of Bonn Medical Center, Bonn, Germany (J.L.); Department of Nuclear Medicine, University of Bonn Medical Center, Bonn, Germany (R.A.B.); Dept. of Nuclear Medicine, University of Aachen, Aachen, Germany (K-J.L.); DKFZ-Division of Translational Oncology / Neurooncology, German Cancer Consortium (DKTK) & University Hospital Essen, Essen, Germany (B.S.); Clinical Cooperation Unit Neurooncology, MediClin Robert Janker Klinik, Bonn, Germany (M.G.) Martin.Glas@ukb.uni-bonn.de.
authors: Martin
authors: M
authors: Glas
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008545:Melanoma / Q000000981:diagnostic imaging*; D009362:Neoplasm Metastasis / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014443:Tyrosine
chemical_list: D019275:Radiopharmaceuticals; D014443:Tyrosine
keywords: FET-PET; brain metastases; melanoma; pseudoprogression.