title: Undifferentiated vasculitis or an evolving systemic autoimmune rheumatic disease?
abstract: Undifferentiated connective tissue diseases usually present with arthralgias, sicca symptoms, Raynaud's phenomenon and leucopenia. This case presents the atypical presentation of an undifferentiated connective tissue disease with extensive cutaneous involvement of fingers and toes leading to gangrene with absence of typical rheumatological symptoms. The autoimmune profile showed positive ANA and anti-Ro/SS-A. Thromboembolism was ruled out on the basis of transthoracic and transesophageal echo. She was treated with I/V corticosteroids and cyclophosphamide that halted the disease progression.
authors: Department of Internal Medicine, Shaikh Zayed Medical Complex , 54600 Lahore , Pakistan.
authors: Nafeesah
authors: N
authors: Fatimah
authors: Department of Internal Medicine, Shaikh Zayed Medical Complex , 54600 Lahore , Pakistan.
authors: Ahmad
authors: A
authors: Ussaid
authors: Department of Rheumatology and Immunology, Shaikh Zayed Medical Complex , 54600 Lahore , Pakistan.
authors: Aflak
authors: A
authors: Rasheed
keywords: Autoimmunity; Undifferentiated connective tissue disease; Vasculitis