title: Mixed serous neuroendocrine neoplasm of the pancreas: Case report and literature review.
abstract: BACKGROUND
  The aim of this study was to report a new case of mixed serous neuroendocrine neoplasm (MSNN) and review the literature concerning this type of lesion, which was added to the World Health Organization classification of pancreatic tumors in 2010.
  
  
  RESULTS
  A 73-year-old woman presented with a pancreatic mass. The lesion was an intriguing combination of serous cystic neoplasm (SCN) and pancreatic neuroendocrine tumor (PanNET), in which the PanNET component grew into the wall of the serous oligocystic adenoma. We searched different databases for studies that had investigated MSNN. A total of 15 patients (age, 28-78), including the patient in the present study, were evaluated. We discuss these cases in detail especially regarding morphology and pathology; our case was the only one involving a collision type combination.
  
  
  CONCLUSIONS
  Although MSNN is recognized as a variant of SCN, it is quite different from SCN or PanNET. A new morphological analysis of MSNN may help in elucidating its histogenesis and prognosis.
authors: Department of General Surgery Department of Pathology, Peking Union Medical College Hospital, Beijing Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, P.R. China.
authors: Yatong
authors: Y
authors: Li
authors: Menghua
authors: M
authors: Dai
authors: Xiaoyan
authors: X
authors: Chang
authors: Wendi
authors: W
authors: Hu
authors: Jie
authors: J
authors: Chen
authors: Junchao
authors: J
authors: Guo
authors: Wenming
authors: W
authors: Wu
authors: Taiping
authors: T
authors: Zhang
authors: Quan
authors: Q
authors: Liao
authors: Ziwen
authors: Z
authors: Liu
authors: Ya
authors: Y
authors: Hu
authors: Yupei
authors: Y
authors: Zhao
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D018193:Neoplasms, Complex and Mixed / Q000000981:diagnostic imaging / Q000473:pathology*; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000000981:diagnostic imaging / Q000473:pathology*; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography