title: A Young Male Patient With Multiple Thromboembolisms Associated With Factor V Leiden Mutation.
abstract: Factor V Leiden (FVL) mutation is the most common hereditary thrombophilia. Association of this mutation with venous thrombosis is well established. However, there are several conflicting results regarding the association of FVL with arterial thrombosis, acute coronary syndrome, and intracardiac thrombosis. In this case report, we present a 44-yearold male patient with a medical history of both arterial and venous thrombosis who came to our emergency department with chest pain. After the initial evaluation he was diagnosed as having acute coronary syndrome and transthoracic echocardiography revealed an intracardiac apical thrombus. Coronary angiography showed non-critical stenosis. Thrombophilia panel was studied and the patient was found to be heterozygotic for FVL mutation. An apical thrombus was extracted surgically because of the high risk of systemic embolization.
authors: Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital.
authors: Göksel
authors: G
authors: Çinier
authors: Ahmet
authors: A
authors: Öz
authors: Ahmet Ilker
authors: AI
authors: Tekkesin
authors: Mert İlker
authors: Mİ
authors: Hayıroğlu
authors: Muhammed
authors: M
authors: Keskin
authors: Şahin
authors: Ş
authors: Avsar
mesh_terms: D000328:Adult; D005165:Factor V / Q000235:genetics*; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics*; D013923:Thromboembolism / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D019851:Thrombophilia / Q000150:complications* / Q000175:diagnosis / Q000235:genetics*
chemical_list: C095381:factor V Leiden; D005165:Factor V