title: Complete genome sequence of the novel duck hepatitis B virus strain SCP01 from Sichuan Cherry Valley duck.
abstract: BACKGROUND
  The duck hepatitis B virus (DHBV) strain, designated SCP01, was isolated and identified from a Sichuan Cherry Valley duck in Southwestern China. To determine the origination and evolution of this isolated strain, we carried out complete genome sequencing of this strain.
  
  
  RESULTS
  Sequencing of the nucleotide sequence of DHBV strain SCP01 revealed a genome size of 3021 bp that contained three open reading frames, designated as C, S, and P, which were consistent with those of other duck hepatitis B viruses nucleotide sequences available in the GenBank of NCBI. Sequence comparisons based on the full-length genomic sequences showed that the DHBV SCP01 strain had the highest similarity (99.64 %) with the sequence of strain DHBV-XY, but had a lower similarity (90.04 %) with the sequence of strain DHBV CH5 isolated from Southwestern China. Phylogenetic analysis revealed that the DHBV-XY and DHBV SCP01 formed a branch that was clearly distinct from the other strains.
  
  
  CONCLUSIONS
  This study show that the DHBV SCP01 strain from Sichuan belonged to "Western" isolates, while the DHBV CH5 from Sichuan belonged to "Chinese" isolates. These data will promote further research into the evolutionary biology, epidemiology and pathobiology of hepadnavirus infections. In addition, continuing duck hepatitis B virus surveillance in poultry is critical to understand the patterns of DHBV infection, and to find further animal infection models to study HBV infection.
authors: Avian Disease Research Center, Sichuan Agricultural University, Chengdu, 611130 China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China.
authors: Qingqing
authors: Q
authors: Li
authors: Avian Disease Research Center, Sichuan Agricultural University, Chengdu, 611130 China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Renyong
authors: R
authors: Jia
authors: Avian Disease Research Center, Sichuan Agricultural University, Chengdu, 611130 China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China.
authors: Siyang
authors: S
authors: Liu
authors: Avian Disease Research Center, Sichuan Agricultural University, Chengdu, 611130 China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Mingshu
authors: M
authors: Wang
authors: Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Dekang
authors: D
authors: Zhu
authors: Avian Disease Research Center, Sichuan Agricultural University, Chengdu, 611130 China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Shun
authors: S
authors: Chen
authors: Avian Disease Research Center, Sichuan Agricultural University, Chengdu, 611130 China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Mafeng
authors: M
authors: Liu
authors: Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Zhongqiong
authors: Z
authors: Yin
authors: Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Bo
authors: B
authors: Jing
authors: Avian Disease Research Center, Sichuan Agricultural University, Chengdu, 611130 China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130 China ; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, 611130 China.
authors: Anchun
authors: A
authors: Cheng
keywords: Cherry valley duck; Chinese and Western isolates; Complete genome sequence; Duck hepatitis B virus; Phylogenetic analysis