title: Surgical treatment of sporadic and von Hippel-Lindau syndrome-associated intramedullary hemangioblastomas.
abstract: OBJECTIVE
  Intramedullary hemangioblastomas are rare lesions. They can be related to von Hippel-Lindau syndrome or they may be sporadic. This study describes surgical treatment for this infrequent tumor.
  
  
  METHODS
  Twelve consecutive patients received surgery to remove sporadic or von Hippel-Lindau syndrome-associated intramedullary hemangioblastomas. Patients were evaluated at four time points: before treatment, on postoperative day one, on the day of discharge, and at a follow-up examination.
  
  
  RESULTS
  The patients showed good preoperative neurological status. The cohort had a slight female predominance. All tumors spanned at least one spinal segment. In all cases, total tumor removal was achieved, and a good outcome was obtained. None of the following factors had a significant effect on outcome: age, sex, tumor size, the presence of a syrinx, or the presence of von Hippel-Lindau syndrome.
  
  
  CONCLUSIONS
  The surgical removal of intramedullary hemangioblastomas resulted in satisfactory long-term functional outcomes. The best results were obtained before neurological symptoms occurred. Thus, we suggest that surgery should be considered for managing asymptomatic, surgically accessible, space-occupying lesions in sIH group, and isolated, space-occupying lesions in vHLS-IH group.
authors: Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland.
authors: Marek
authors: M
authors: Prokopienko
authors: Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland. Electronic address: pkunert@wp.pl.
authors: Przemysław
authors: P
authors: Kunert
authors: Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland.
authors: Anna
authors: A
authors: Podgórska
authors: Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland.
authors: Andrzej
authors: A
authors: Marchel
mesh_terms: D000293:Adolescent; D000328:Adult; D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D018325:Hemangioblastoma / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D064795:Intraoperative Neurophysiological Monitoring; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult; D006623:von Hippel-Lindau Disease / Q000150:complications*
keywords: Hemangioblastoma; Intramedullary tumor; von Hippel–Lindau syndrome