title: Porphyria cutanea tarda in a HIV- positive patient.
abstract: This is a case report about Porphyria cutanea tarda (PCT) and its relationship with the infection caused by the human immunodeficiency virus (HIV). Cutaneous porphyria is an illness caused by enzymatic modification that results in partial deficiency of uroporphyrinogen decarboxylase (Urod), which may be hereditary or acquired. Several studies suggest that HIV infection associated with cofactors might trigger the development of porphyria cutanea tarda. In this case report, we present a patient infected with HIV, who after the introduction of antiretroviral therapy (ART) enjoyed clinical improvement of porphyria cutanea tarda symptoms.
authors: Pontifícia Universidade Católica do Paraná (PUCPR) - Curitiba (PR), Brazil.|Fundação Pró-Hansen - Curitiba (PR), Brazil.
authors: Valéria Aparecida Zanela
authors: VA
authors: Franzon
authors: Pontifícia Universidade Católica do Paraná (PUCPR) - Curitiba (PR), Brazil.
authors: Emanuella Stella
authors: ES
authors: Mikilita
authors: Pontifícia Universidade Católica do Paraná (PUCPR) - Curitiba (PR), Brazil.
authors: Fernanda Henriques
authors: FH
authors: Camelo
authors: Pontifícia Universidade Católica do Paraná (PUCPR) - Curitiba (PR), Brazil.|Hospital Oswaldo Cruz - Curitiba (PR), Brazil.
authors: Rosana
authors: R
authors: Camargo
mesh_terms: D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D017119:Porphyria Cutanea Tarda / Q000188:drug therapy / Q000473:pathology* / Q000821:virology*; D012307:Risk Factors; D012867:Skin / Q000473:pathology; D014575:Uroporphyrinogen Decarboxylase / Q000652:urine
chemical_list: D014575:Uroporphyrinogen Decarboxylase