title: Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients.
abstract: The records of 70 patients with oral cancer who were treated at a single institution between 2008 and 2014 were reviewed. The body temperature, white blood cell count, and C-reactive protein (CRP) levels were compared between those who had received preoperative oral care (oral care group) and those who had not received any (non-oral care group). When the patients were divided into those who underwent minimally invasive surgery and those who underwent severely invasive surgery, the mean CRP level in the early postoperative period was lower in the oral care group as compared with the non-oral care group in those who underwent minimally invasive surgery as well as those who underwent severely invasive surgery. However, the mean CRP level was most evidently reduced in the severely invasive group on days 1 and 3-5. However, no significant differences were observed with regard to the percentage of postoperative infectious complications (for example, surgical site infection, anastomotic leak and pneumonia) between the oral care (13.6%) and non-oral care (20.8%) groups, though a reduced prevalence of postoperative complications following preoperative oral care was noted. The results of the present study suggest that preoperative oral care can decrease inflammation during the early postoperative stage in patients with oral cancer who undergo severely invasive surgery.
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Hideo
authors: H
authors: Shigeishi
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Kouji
authors: K
authors: Ohta
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Shinichi
authors: S
authors: Fujimoto
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Takayuki
authors: T
authors: Nakagawa
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Kuniko
authors: K
authors: Mizuta
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Shigehiro
authors: S
authors: Ono
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Hiroshi
authors: H
authors: Shimasue
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Yoshiaki
authors: Y
authors: Ninomiya
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Koichiro
authors: K
authors: Higashikawa
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Misato
authors: M
authors: Tada
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Fumi
authors: F
authors: Ishida
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Gaku
authors: G
authors: Okui
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Toshiya
authors: T
authors: Okumura
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Akiko
authors: A
authors: Fukui
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Kazumi
authors: K
authors: Kubozono
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Kazuhiro
authors: K
authors: Yamamoto
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Yoko
authors: Y
authors: Ishida
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Sayaka
authors: S
authors: Seino
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Miho
authors: M
authors: Hashikata
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Kazuki
authors: K
authors: Sasaki
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Takako
authors: T
authors: Naruse
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Mohammad Zeshaan
authors: MZ
authors: Rahman
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Ryo
authors: R
authors: Uetsuki
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Akiko
authors: A
authors: Nimiya
authors: Oral Hygiene Section, Hiroshima University Hospital, Hiroshima 734-8553, Japan.
authors: Megumi
authors: M
authors: Takamoto
authors: Oral Hygiene Section, Hiroshima University Hospital, Hiroshima 734-8553, Japan.
authors: Kana
authors: K
authors: Dainobu
authors: Oral Hygiene Section, Hiroshima University Hospital, Hiroshima 734-8553, Japan.
authors: Tomoko
authors: T
authors: Tokikazu
authors: Department of General Dentistry, Hiroshima University Hospital, Hiroshima 734-8553, Japan.
authors: Hiromi
authors: H
authors: Nishi
authors: Department of Public Oral Health, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Masaru
authors: M
authors: Sugiyama
authors: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
authors: Masaaki
authors: M
authors: Takechi
keywords: oral cancer; oral health care; retrospective study