title: Advanced MRI manifestations of trigeminal ganglioneuroma: a case report and literature review.
abstract: Ganglioneuroma is a rare benign tumor originating from the sympathetic nerves, and its origination from the trigeminal nerves is even rarer. Only 4 cases of ganglioneuroma originating from the trigeminal nerve have previously been reported, and these studies only reported conventional MRI manifestations. To our knowledge, the advanced MRI features of trigeminal ganglioneuroma have not been reported thus far.
  
  
  
  This study reports a case of trigeminal ganglioneuroma in the left cerebellopontine angle. Advanced MRI showed the following tumor characteristics: significantly increased perfusion on perfusion imaging; isointense on diffusion-weighted imaging, whorled appearance within the tumor and no significant signs of damage to the white matter fiber tracts in the fractional anisotropy color map, and compare to the adjacent brain tissue, Choline didn't show markedly elevation, and N-acetylaspartate peak showed slightly reduction on magnetic resonance spectroscopy. The tumor was completely resected, and the diagnosis of ganglioneuroma was confirmed by postoperative pathological examination.
  
  
  
  This case demonstrates the conventional as well as advanced MRI manifestations of this rare extra-axial tumor, which have never been previously reported. In addition, we reviewed the literature to demonstrate the advanced MRI features of trigeminal ganglioneuroma, in order to aid preoperative diagnosis and differentiation.
authors: Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, 400042, Chongqing, China.
authors: Xiaojuan
authors: X
authors: Deng
authors: Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, 400042, Chongqing, China.
authors: Jingqin
authors: J
authors: Fang
authors: Department of Pathology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China.
authors: Qingya
authors: Q
authors: Luo
authors: Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, 400042, Chongqing, China.
authors: Haipeng
authors: H
authors: Tong
authors: Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, 400042, Chongqing, China. wgzhang01@163.com.|State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China. wgzhang01@163.com.
authors: Weiguo
authors: W
authors: Zhang
mesh_terms: D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D005729:Ganglioneuroma / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D014276:Trigeminal Nerve / Q000000981:diagnostic imaging / Q000473:pathology; D020433:Trigeminal Nerve Diseases / Q000000981:diagnostic imaging; D055815:Young Adult
keywords: Diffusion tensor imaging; Diffusion-weighted imaging; MR spectroscopy; Trigeminal ganglioneuroma; magnetic resonance imaging