title: Predictors of recurrence after stent-assisted coil embolization of paraclinoid aneurysms.
abstract: Stent-assisted coil embolization has been increasingly used to treat paraclinoid aneurysms. The study was aimed to evaluate safety and efficacy of stent-assisted coil embolization for paraclinoid aneurysms and explore the factors influencing the long-term outcomes. Under an institutional review board approved protocol, the clinical and angiographic data of 129 paraclinoid aneurysms in 120 patients (Male:Female=36:84; median age, 52years; range, 21-84) treated by stent-assisted coil embolization were reviewed retrospectively. Clinical status, aneurysmal morphology, treatment strategy and results were analyzed using Chi-squared tests in the univariate analysis and further analyzed using backward stepwise logistic regression. The univariate analysis indicated significance between the groups regarding hypertension, ruptured aneurysms, size, wide neck and immediate treatment results (P<0.05). Multivariate logistic regression analysis found that ruptured aneurysms (odds ratio [OR]=5.893, 95% confidence interval [CI], 1.512-23.054; p=0.011), larger size (OR=2.339; 95%CI, 1.148-4.781; p=0.020) and hypertension (OR=6.143; 95%CI, 1.560-24.183; p=0.009) might be predictors of recurrence. Stent-assisted coil embolization of paraclinoid aneurysm has a risk of recurrence. Ruptured aneurysms, larger size and hypertension may be the risk factors for recurrence.
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Nan
authors: N
authors: Lv
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Rui
authors: R
authors: Zhao
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Pengfei
authors: P
authors: Yang
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Yibin
authors: Y
authors: Fang
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Qiang
authors: Q
authors: Li
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Yi
authors: Y
authors: Xu
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Bo
authors: B
authors: Hong
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Wenyuan
authors: W
authors: Zhao
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China.
authors: Jianmin
authors: J
authors: Liu
authors: Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Changhai Road 168, Shanghai 200433, China. Electronic address: ocinhqh@163.com.
authors: Qinghai
authors: Q
authors: Huang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000628:therapy*; D001807:Blood Vessel Prosthesis; D002533:Cerebral Angiography / Q000379:methods; D004621:Embolization, Therapeutic / Q000295:instrumentation / Q000639:trends*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012008:Recurrence; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome; D055815:Young Adult
keywords: Endovascular treatment; Intracranial aneurysm; Paraclinoid aneurysm; Recurrence; Stent-assisted coil embolization