title: Melasma.
abstract: Melasma is a common acquired hypermelanosis that primarily affects women of skin type IV-VI. It tends to appear on sun-exposed areas of face and neck. The exact pathogenesis is linked with many factors include ultraviolet radiation, pregnancy, hormonal activity, thyroid abnormalities, and medications. Melasma, which involves increased melanin production and melanocytosis, may be principally epidermal, dermal, or mixed. Mainstays of treatment include topical hypopigmenting agents, lasers, chemical peels, and dermabrasion.
authors: Departments of Dermatology and Pathology, Rutgers University New Jersey Medical School, Newark, NJ, USA.
authors: Brian W
authors: BW
authors: Lee
authors: Departments of Dermatology and Pathology, Rutgers University New Jersey Medical School, Newark, NJ, USA.|Rutgers University School of Public Affairs and Administration, Newark, NJ, USA.
authors: Robert A
authors: RA
authors: Schwartz
authors: Departments of Dermatology and Pathology, Rutgers University New Jersey Medical School, Newark, NJ, USA - cjanniger@yahoo.com.
authors: Camila K
authors: CK
authors: Janniger
mesh_terms: D002615:Chemexfoliation / Q000379:methods; D003869:Dermabrasion / Q000379:methods; D003879:Dermatologic Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods; D008548:Melanosis / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D011247:Pregnancy; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D003879:Dermatologic Agents