title: Patient-related factors that influence coronary artery density in CCTA: a retrospective clinical study.
abstract: OBJECTIVE
  The aim of this study was to investigate the relationship between various patient-related factors (physical and cardiac hemodynamic parameters) and the coronary artery density on coronary CT angiography (CCTA).
  
  
  METHODS
  A total of 64 patients (female: male ratio, 24:40; age, 58.2 years±9.3, age range, 31-81 years; mean body weight, 65.3 kg±11.6, range 40-88 kg) were effectively enrolled in this approved retrospective study. Patient-related physical factors including height, body weight (BW), body mass index (BMI), systolic blood pressure (BPsys), diastolic blood pressure (BPdis) and blood pulse pressure (Bp) were recorded, measured and calculated prior to the administration of contrast media during the CCTA. Patient-related cardiac hemodynamic parameters, including heart rate (HR), myocardial mass (MM), cardiac output (CO), ejection fraction (EF), end-diastolic dimension (EDV), end-systolic volume (ESV) and stroke volume (SV), were analysed and recorded on the multimodality workplace (MMWP). The mean attenuation values of the left main artery (LMA) were measured and calculated. The correlation of the mean attenuation in the coronary arteries with the physical and hemodynamic parameters was evaluated. The correlations between the physical factors and hemodynamic parameters were also calculated.
  
  
  RESULTS
  A significant negative linear correlation was found between the attenuation of the left main artery (LMA) and BW (P=.001), BMI (P=.006), CO (P=.008), EDV (P=.001) and MM (P<.001). Significant linear correlations were obtained between CO and HR (P<.001), EDV and BW (P=.001) and MM and BW (P<.001).
  
  
  CONCLUSIONS
  Coronary artery attenuation depends on the patient's specific physical and cardiac function status.
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Peng
authors: P
authors: Cao
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Miao
authors: M
authors: He
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Chen
authors: C
authors: Qiao
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Nan
authors: N
authors: Xu
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Daoyi
authors: D
authors: Huang
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Gonghua
authors: G
authors: Dai
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Yibin
authors: Y
authors: Wang
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Haihong
authors: H
authors: Pan
authors: Department of Radiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
authors: Lei
authors: L
authors: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002302:Cardiac Output; D000072226:Computed Tomography Angiography; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013318:Stroke Volume