title: Cross-sectional associations of objectively measured physical activity and sedentary time with sarcopenia and sarcopenic obesity in older men.
abstract: This study investigated associations between objectively measured physical activity (PA) with sarcopenia and sarcopenic obesity in older British men. Participants were men aged 70-92years (n=1286) recruited from UK Primary Care Centres. Outcomes included (i) sarcopenia, defined as low muscle mass (lowest two fifths of the mid-upper arm muscle circumference distribution) accompanied by low muscular strength (hand grip strength <30kg) or low physical performance (gait speed≤0.8m/s); (ii) severe sarcopenia, required all three conditions; (iii) sarcopenic obesity defined as sarcopenia or severe sarcopenia and a waist circumference of >102cm. Independent variables included time spent in PA intensities measured by GT3x accelerometers, worn during one week in 2010-12. Multinomial regression models were used for cross-sectional analyses relating PA and sarcopenia. In total, 14.2% (n=183) of men had sarcopenia and a further 5.4% (n=70) had severe sarcopenia. 25.3% of sarcopenic or severely sarcopenic men were obese. Each extra 30min per day of moderate-to-vigorous PA (MVPA) was associated with a reduced risk of severe sarcopenia (relative risk [RR] 0.53, 95% confidence interval [CI] 0.30, 0.93) and sarcopenic obesity (RR 0.47 [95% CI 0.27, 0.84]). Light PA (LPA) and sedentary breaks were marginally associated with a reduced risk of sarcopenic obesity. Sedentary time was marginally associated with an increased risk of sarcopenic obesity independent of MVPA (RR 1.18 [95% CI 0.99, 1.40]). MVPA may reduce the risk of severe sarcopenia and sarcopenic obesity among older men. Reducing sedentary time and increasing LPA and sedentary breaks may also protect against sarcopenic obesity.
authors: UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK; UCL Physical Activity Research Group, UK. Electronic address: d.aggio@ucl.ac.uk.
authors: Daniel A
authors: DA
authors: Aggio
authors: UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK; UCL Physical Activity Research Group, UK.
authors: Claudio
authors: C
authors: Sartini
authors: UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK.
authors: Olia
authors: O
authors: Papacosta
authors: UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK.
authors: Lucy T
authors: LT
authors: Lennon
authors: UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK.
authors: Sarah
authors: S
authors: Ash
authors: Population Health Research Institute, St George's University of London, Cranmer Terrace, London. SW17 0RE, UK.
authors: Peter H
authors: PH
authors: Whincup
authors: UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK; UCL Physical Activity Research Group, UK.
authors: S Goya
authors: SG
authors: Wannamethee
authors: UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London NW3 2PF, UK; UCL Physical Activity Research Group, UK.
authors: Barbara J
authors: BJ
authors: Jefferis
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology*; D018737:Hand Strength; D006801:Humans; D008297:Male; D053580:Muscle Strength; D009765:Obesity / Q000453:epidemiology*; D055948:Sarcopenia / Q000453:epidemiology*; D057185:Sedentary Behavior; D006113:United Kingdom / Q000453:epidemiology
keywords: Muscle mass; Physical activity; Sarcopenia; Sarcopenic obesity