title: Formal thought disorder in first-episode psychosis.
abstract: Formal thought disorder (FTD) is one of the fundamental symptom clusters of schizophrenia and it was found to be the strongest predictor determining conversion from first-episode acute transient psychotic disorder to schizophrenia. Our goal in the present study was to compare a first-episode psychosis (FEP) sample to a healthy control group in relation to subtypes of FTD. Fifty six patients aged between 15 and 45years with FEP and forty five control subjects were included in the study. All the patients were under medication for less than six weeks or drug-naive. FTD was assessed using the Thought and Language Index (TLI), which is composed of impoverishment of thought and disorganization of thought subscales. FEP patients showed significantly higher scores on the items of poverty of speech, weakening of goal, perseveration, looseness, peculiar word use, peculiar sentence construction and peculiar logic compared to controls. Poverty of speech, perseveration and peculiar word use were the significant factors differentiating FEP patients from controls when controlling for years of education, family history of psychosis and drug abuse.
authors: Manisa Psychiatric Hospital, Manisa, Turkey.
authors: Ahmet
authors: A
authors: Ayer
authors: Department of Neuroscience, Dokuz Eylul University, Izmir, Turkey.
authors: Berna
authors: B
authors: Yalınçetin
authors: Department of Neuroscience, Dokuz Eylul University, Izmir, Turkey.
authors: Esra
authors: E
authors: Aydınlı
authors: Department of Neuroscience, Dokuz Eylul University, Izmir, Turkey.
authors: Şilay
authors: Ş
authors: Sevilmiş
authors: Department of Psychiatry, Medical School of Dokuz Eylul University, Izmir, Turkey.
authors: Halis
authors: H
authors: Ulaş
authors: Department of Psychiatry, Medical School of Dokuz Eylul University, Izmir, Turkey.
authors: Tolga
authors: T
authors: Binbay
authors: Department of Neuroscience, Dokuz Eylul University, Izmir, Turkey; Department of Psychiatry, Medical School of Dokuz Eylul University, Izmir, Turkey.
authors: Berna Binnur
authors: BB
authors: Akdede
authors: Department of Neuroscience, Dokuz Eylul University, Izmir, Turkey; Department of Psychiatry, Medical School of Dokuz Eylul University, Izmir, Turkey. Electronic address: koksal.alptekin@deu.edu.tr.
authors: Köksal
authors: K
authors: Alptekin
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000175:diagnosis / Q000523:psychology; D009483:Neuropsychological Tests; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology*; D013850:Thinking; D055815:Young Adult