title: Ibuprofen-related renal tubular acidosis in pregnancy.
abstract: Ibuprofen-related renal tubular acidosis (RTA) has not been previously described in pregnancy but its occurrence outside of pregnancy is being increasingly described. In this case, a 34-year-old woman presented in the third trimester of pregnancy with Type 1 or distal RTA related to ibuprofen and codeine abuse. It was complicated by acute on chronic renal dysfunction and hypokalemia. Delivery at 37 weeks gestation due to concerns of evolving preeclampsia resulted in the birth of a healthy neonate. RTA and hypokalemia were remediated and ibuprofen and codeine abuse ceased. Some renal dysfunction however continued. Thorough and repeated history taking as well as vigilance for this condition is suggested.
authors: Department of Renal Medicine; Department of Obstetric Medicine, Royal Brisbane and Women's Hospital, Butterfield Street, Herston, Brisbane, Queensland, 4029, Australia.
authors: Andrew
authors: A
authors: Mallett
authors: Mount Isa Base Hospital , Mount Isa , Australia.
authors: Matthew
authors: M
authors: Lynch
authors: Department of Renal Medicine.
authors: George T
authors: GT
authors: John
authors: Department of Renal Medicine.
authors: Helen
authors: H
authors: Healy
authors: Department of Obstetric Medicine , Royal Brisbane and Women's Hospital , Butterfield Street, Herston, Brisbane, Queensland, 4029 , Australia.
authors: Karin
authors: K
authors: Lust
keywords: clinical pharmacology; drugs (medication); maternal-fetal medicine; nephrology