title: Increased Incidence of Early Onset Colorectal Cancer in Arizona: A Comprehensive 15-year Analysis of the Arizona Cancer Registry.
abstract: BACKGROUND
  The aim of this study was to investigate and analyze the incidence of early-onset colorectal cancer in Arizona, using the Arizona Cancer Registry.
  
  
  METHODS
  We performed a retrospective analysis of patients with colorectal cancer reported in the Arizona Cancer Registry from 1995-2010. Outcome measure: incidence of CRC in patients younger than 50 years.
  
  
  RESULTS
  39,623 cases of colorectal cancer were reported to the Arizona Cancer Registry during a period of 15 years. Overall, there was a 17% decrease in the incidence of CRC. However, there was a 23% increase in incidence among patients in the age group 10-50. During the same time period, 15% and 41% increase in the incidence of colon and rectal cancer was observed, respectively. The most significant increase (102%) in overall CRC incidence was seen in the age group 10-29. The highest increase (110%) in incidence of colon cancer was observed in the same age group, while the most significant increase in incidence rates (225%) of rectal cancer was seen in the age group 30-34.
  
  
  CONCLUSIONS
  Although there is an overall decrease in incidence of colorectal cancer in Arizona, alarming increase in incidence of early-onset CRC was observed; mirroring the national trends.
authors: Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
authors: Hassan
authors: H
authors: Aziz
authors: Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
authors: Viraj
authors: V
authors: Pandit
authors: Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
authors: Ryan M
authors: RM
authors: DiGiovanni
authors: Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
authors: Eric
authors: E
authors: Ohlson
authors: Department of Epidemiology and Biostatistics Division, University of Arizona, Tucson, AZ.
authors: Angelika C
authors: AC
authors: Gruessner
authors: Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ; Department of Pathology, University of Arizona, Tucson, AZ.
authors: Jana
authors: J
authors: Jandova
authors: Department of Surgery, Division of Surgical Oncology, University of Arizona, Tucson, AZ.
authors: Valentine N
authors: VN
authors: Nfonsam