title: Seroprevalence of human immunodeficiency virus among voluntary counseling and testing clients at the University of Gondar Teaching Hospital, Northwest Ethiopia.
abstract: BACKGROUND
  The epidemiology of human immunodeficiency virus (HIV) infection in Ethiopia varies with regions, study population, and time. Thus, timely information on HIV epidemiology is critical for the combat of the epidemic. In this study, we aim to update HIV prevalence and risk factors among voluntary counseling and testing (VCT) clients at the University of Gondar Teaching Hospital, Northwest Ethiopia.
  
  
  METHODS
  A total of 2,120 VCT clients' records from September 2007 to August 2010 were analyzed retrospectively. Bivariate logistic regression analysis was used to identify significant predictors. Odds ratio (OR) and 95% confidence intervals (CIs) were calculated. Statistical significance was set at P-value <0.05.
  
  
  RESULTS
  Of 2,120 VCT clients, 363 (17.1%) were seropositive for HIV. A higher rate of HIV positivity was observed among female clients (20.4%) than that in male clients (14.0%) (OR 1.58, 95% CI 1.26-1.98, P=0.00). Widowed (95% CI 10.42-34.92, P=0.00), married (95% CI 3.42-5.94, P=0.00), divorced (95% CI 2.79-5.32, P=0.00), and illiterate (95% CI 2.33-5.47, P=0.00) clients were associated with HIV infection with the odds ratios of 19.07, 4.51, 3.85, and 3.57, respectively. Clients within the age category of 35-49 years (OR 5.03, 95% CI 3.56-7.12, P=0.00) and above the age of 50 years (OR 4.99, 95% CI 2.67-9.34, P=0.00) were more likely to be infected with HIV.
  
  
  CONCLUSIONS
  HIV is still the major concern of public health in the Gondar area as evidenced by our data. Being female, widowed, married, illiterate, and older age were the identified risk factors for HIV infection. Thus, consideration of these factors in future intervention and clinical practice is recommended.
authors: School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar; Diagnostic Laboratory Case Team, University of Gondar Teaching Hospital, Gondar, Ethiopia.
authors: Yohannes
authors: Y
authors: Sinku
authors: School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar.
authors: Takele
authors: T
authors: Gezahegn
authors: School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar.
authors: Yalewayiker
authors: Y
authors: Gashaw
authors: School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar.
authors: Meseret
authors: M
authors: Workineh
authors: School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar.
authors: Tekalign
authors: T
authors: Deressa
keywords: AIDS; HIV; Northwest Ethiopia; prevalence; voluntary counseling and testing