title: Data Analysis for High-Throughput RNAi Screening.
abstract: High-throughput RNA interference (HT-RNAi) screening is an effective technology to help identify important genes and pathways involved in a biological process. Analysis of high-throughput RNAi screening data is a critical part of this technology, and many analysis methods have been described. Here, we summarize the workflow and types of analyses commonly used in high-throughput RNAi screening.
authors: Institute of Molecular Medicine, Phoenix Children's Hospital, Phoenix, AZ, USA. dazorsa@email.arizona.edu.|Department of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, USA. dazorsa@email.arizona.edu.
authors: David O
authors: DO
authors: Azorsa
authors: Department of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, USA.|School of Life Sciences, Arizona State University, Tempe, AZ, USA.
authors: Megan A
authors: MA
authors: Turnidge
authors: Constellation Pharmaceuticals, Cambridge, MA, USA.
authors: Shilpi
authors: S
authors: Arora
mesh_terms: D057166:High-Throughput Screening Assays / Q000379:methods*; D011786:Quality Control; D034622:RNA Interference; D034741:RNA, Small Interfering; D057188:Workflow
chemical_list: D034741:RNA, Small Interfering
keywords: Data analysis; Normalization; RNAi screening