title: Microbicidal effects of plain soap vs triclocarban-based antibacterial soap.
abstract: The aim of this study was to determine the bactericidal effects of plain and antibacterial soap. The bactericidal effects of plain and antibacterial soap containing 0.3% triclocarban were examined against 10 Gram-positive and 10 Gram-negative bacterial strains after exposure at 22°C and 40°C for 20 s. Gram-negative bacteria were more susceptible to both soaps than Gram-positive bacteria. However, with one exception (Enterococcus faecalis ATCC 19433 at 40°C), there was no significant difference between the effects of medicated and non-medicated soap at either temperature. Triclocarban in soap does not lead to a meaningful reduction in bacterial levels during use.
authors: Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
authors: S A
authors: SA
authors: Kim
authors: Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea. Electronic address: rheems@korea.ac.kr.
authors: M S
authors: MS
authors: Rhee
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002224:Carbanilides / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000502:physiology; D006094:Gram-Positive Bacteria / Q000187:drug effects* / Q000502:physiology; D050296:Microbial Viability / Q000187:drug effects*; D012915:Soaps / Q000494:pharmacology*; D013696:Temperature; D013997:Time Factors
chemical_list: D000890:Anti-Infective Agents; D002224:Carbanilides; D012915:Soaps; C009540:triclocarban
keywords: Antibacterial soap; Antiseptic active ingredient; Bactericidal effect; Hand soap; Triclocarban