title: Tell me twice: A multi-study analysis of the functional connectivity between the cerebrum and cerebellum after repeated trait information.
abstract: This multi-study analysis (6 fMRI studies; 142 participants) explores the functional activation and connectivity of the cerebellum with the cerebrum during repeated behavioral information uptake informing about personality traits of different persons. The results suggest that trait repetition recruits activity in areas belonging to the mentalizing and executive control networks in the cerebrum, and the executive control areas in the cerebellum. Cerebral activation was observed in the executive control network including the posterior medial frontal cortex (pmFC), the bilateral prefrontal cortex (PFC) and bilateral inferior parietal cortex (IPC), in the mentalizing network including the bilateral middle temporal cortex (MTC) extending to the right superior temporal cortex (STC), as well as in the visual network including the left cuneus (Cun) and the left inferior occipital cortex. Moreover, cerebellar activation was found bilaterally in lobules VI and VII belonging to the executive control network. Importantly, significant patterns of functional connectivity were found linking these cerebellar executive areas with cerebral executive areas in the medial pmFC, the left PFC and the left IPC, and mentalizing areas in the left MTC. In addition, connectivity was found between the cerebral areas in the left hemisphere involved in the executive and mentalizing networks, as well as with their homolog areas in the right hemisphere. The discussion centers on the role of these cerebello-cerebral connections in matching internal predictions generated by the cerebellum with external information from the cerebrum, presumably involving the sequencing of behaviors.
authors: Faculty of Psychology and Educational Sciences, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium. Electronic address: Frank.VanOverwalle@vub.ac.be.
authors: Frank
authors: F
authors: Van Overwalle
authors: Faculty of Psychology and Educational Sciences, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
authors: Elien
authors: E
authors: Heleven
authors: School of Psychology, South China Normal University, Guangzhou, China.
authors: Ning
authors: N
authors: Ma
authors: Faculty of Arts, Clinical and Experimental Neurolinguistics, CLIN, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium; Department of Neurology and Memory Clinic, ZNA Middelheim Hospital, Lindendreef 1, B-2020 Antwerp, Belgium.
authors: Peter
authors: P
authors: Mariën
mesh_terms: D002531:Cerebellum / Q000000981:diagnostic imaging / Q000502:physiology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000502:physiology*; D063132:Connectome / Q000379:methods*; D056344:Executive Function / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D056345:Theory of Mind / Q000502:physiology*
keywords: Cerebellum; Executive control; Functional connectivity; Functional neuroimaging; Mentalizing; Trait repetition