title: Financial Relationships With Industry Among National Comprehensive Cancer Network Guideline Authors.
abstract: OBJECTIVE
  Financial conflicts of interest (FCOIs) among authors of clinical practice guidelines have the potential to influence treatment recommendations.
  
  
  OBJECTIVE
  To quantify FCOIs with industry among authors of the National Comprehensive Cancer Network (NCCN) guidelines.
  
  
  METHODS
  We assessed FCOIs occurring during 2014 among NCCN guideline authors in the United States. All were physician members of the NCCN guideline committees for lung, breast, prostate, and colorectal cancer as of the end of 2014. The data source for FCOIs was Open Payments, which is publically reported by the Centers for Medicare and Medicaid Services. This study was cross-sectional.
  
  
  METHODS
  The proportion of NCCN authors having FCOIs with industry; the average amount received from industry sources per author.
  
  
  RESULTS
  Of 125 guideline authors, 108 (86%) had at least 1 reported FCOI. Authors received an average of $10 011 (range, $0-$106 859) in general payments (GPs), which include consulting, meals, lodging, and similar transfers of value, and $236 066 (range $0-$2 756 713) in industry research payments (RPs), including funding associated with clinical trials. Approximately 84% of authors received GPs, while 47% received RPs. Eight (6%) had FCOIs in excess of the $50 000 net and/or $20 000 single-company maximums stipulated by NCCN.
  
  
  CONCLUSIONS
  Among NCCN guideline authors, FCOIs involving RPs were of greater value, while those involving GPs were more prevalent. Although FCOIs may result from engaging in important scholarship, FCOIs may still influence guideline authors in counterproductive ways. Research is needed to understand how best to manage author FCOIs during guideline creation.
authors: Department of Hematology/Oncology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill.
authors: Aaron P
authors: AP
authors: Mitchell
authors: Department of Hematology/Oncology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill.
authors: Ethan M
authors: EM
authors: Basch
authors: Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill3UNC Eshelman School of Pharmacy, Division of Pharmaceutical Outcomes and Policy, University of North Carolina at Chapel Hill, Chapel Hill4Gillings School of Global Public Health, Department of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill5Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill.
authors: Stacie B
authors: SB
authors: Dusetzina
mesh_terms: D014487:Centers for Medicare and Medicaid Services, U.S.; D016265:Conflict of Interest / Q000191:economics*; D004345:Drug Industry / Q000191:economics*; D005378:Financial Support; D017408:Guidelines as Topic; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000191:economics* / Q000453:epidemiology; D010820:Physicians; D014481:United States; D000078329:Workforce