title: Simulation of the modulation transfer function dependent on the partial Fourier fraction in dynamic contrast enhancement magnetic resonance imaging.
abstract: The image characteristics in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) depend on the partial Fourier fraction and contrast medium concentration. These characteristics were assessed and the modulation transfer function (MTF) was calculated by computer simulation. A digital phantom was created from signal intensity data acquired at different contrast medium concentrations on a breast model. The frequency images [created by fast Fourier transform (FFT)] were divided into 512 parts and rearranged to form a new image. The inverse FFT of this image yielded the MTF. From the reference data, three linear models (low, medium, and high) and three exponential models (slow, medium, and rapid) of the signal intensity were created. Smaller partial Fourier fractions, and higher gradients in the linear models, corresponded to faster MTF decline. The MTF more gradually decreased in the exponential models than in the linear models. The MTF, which reflects the image characteristics in DCE-MRI, was more degraded as the partial Fourier fraction decreased.
authors: Department of Radiology, Osaka Red Cross Hospital, 5-30 Fudegasaki, Tennouji-ku, Osaka, 543-8555, Japan. pcblue2@yahoo.co.jp.|Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan. pcblue2@yahoo.co.jp.
authors: Yasuo
authors: Y
authors: Takatsu
authors: Department of Radiology, Saito Yukoukai Hospital, 7-2-18 Saito-asagi, Ibaraki, Osaka, 567-0085, Japan.
authors: Tsuyoshi
authors: T
authors: Ueyama
authors: Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan.
authors: Tosiaki
authors: T
authors: Miyati
authors: Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan.|Department of Radiology, Osaka Medical College Hospital, 2-7, Daigaku-cho, Takatsuki, 569-8686, Japan.
authors: Kenichirou
authors: K
authors: Yamamura
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D003287:Contrast Media / Q000737:chemistry*; D005583:Fourier Analysis; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D012815:Signal Processing, Computer-Assisted
chemical_list: D003287:Contrast Media
keywords: Dynamic study; Magnetic resonance imaging; Modulation transfer function; Partial Fourier fraction