title: Mastitis Modifies the Biogenic Amines Profile in Human Milk, with Significant Changes in the Presence of Histamine, Putrescine and Spermine.
abstract: Biogenic amines (BAs) are low molecular weight nitrogenous organic compounds with different biological activities. Putrescine, spermidine and spermine are essential for the development of the gut and immune system of newborns, and are all found in human milk. Little is known, however, about the role of histamine, tyramine or cadaverine in breast milk. Nor is it known whether mastitis alters the BA composition of milk. The BA profile of human milk, and the influence of mastitis on BA concentrations, were therefore investigated. Putrescine, spermidine and spermine were the main BAs detected. In mastitis-affected milk, the concentrations of putrescine, spermine and histamine were higher.
authors: Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Paseo Río Linares s/n 33300, Villaviciosa, Spain.
authors: Marta
authors: M
authors: Perez
authors: Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Paseo Río Linares s/n 33300, Villaviciosa, Spain.
authors: Victor
authors: V
authors: Ladero
authors: Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Paseo Río Linares s/n 33300, Villaviciosa, Spain.
authors: Begoña
authors: B
authors: Redruello
authors: Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Paseo Río Linares s/n 33300, Villaviciosa, Spain.
authors: Beatriz
authors: B
authors: Del Rio
authors: Departamento de Nutrición, Bromatología y Tecnología de los Alimentos, Universidad Complutense de Madrid, Ciudad Universitaria, Avda. Puerta de Hierro, Madrid, 28040, Spain.
authors: Leonides
authors: L
authors: Fernandez
authors: Departamento de Nutrición, Bromatología y Tecnología de los Alimentos, Universidad Complutense de Madrid, Ciudad Universitaria, Avda. Puerta de Hierro, Madrid, 28040, Spain.
authors: Juan Miguel
authors: JM
authors: Rodriguez
authors: Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Paseo Río Linares s/n 33300, Villaviciosa, Spain.
authors: M Cruz
authors: MC
authors: Martín
authors: Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Paseo Río Linares s/n 33300, Villaviciosa, Spain.
authors: María
authors: M
authors: Fernandez
authors: Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Paseo Río Linares s/n 33300, Villaviciosa, Spain.
authors: Miguel A
authors: MA
authors: Alvarez
mesh_terms: D000818:Animals; D006632:Histamine / Q000008:administration & dosage*; D006801:Humans; D008892:Milk; D011700:Putrescine / Q000008:administration & dosage*
chemical_list: D006632:Histamine; D011700:Putrescine