title: Topical difluprednate for treatment of serous retinal detachment and panuveitis associated with Vogt-Koyanagi-Harada disease.
abstract: Patients with bilateral serous retinal detachments and panuveitis related to Vogt-Koyanagi-Harada disease are commonly managed with oral corticosteroids, immunosuppressive agents, and/or intravitreal injections. We present the case of a 56-year-old Hispanic man with Harada disease whose bilateral serous retinal detachments and panuveitis were treated with topical corticosteroid difluprednate alone. Functional and anatomical recoveries were assessed by fluorescein angiograms and optical coherence tomography studies over a period of 9 months. The patient's serous retinal detachments resolved, and his vision and panuveitis improved dramatically over a period of 2 weeks, after which he was placed on a drop taper and maintenance therapy for the remainder of the 9 months.
authors: Macula Retina Vitreous Center, Torrance, California.
authors: Stacey
authors: S
authors: Lu
authors: Macula Retina Vitreous Center, Torrance, California.
authors: Mehran
authors: M
authors: Taban
mesh_terms: D005451:Fluorescein Angiography; D005477:Fluprednisolone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D058449:Intravitreal Injections; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D015864:Panuveitis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D012163:Retinal Detachment / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D041623:Tomography, Optical Coherence; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications* / Q000175:diagnosis; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D005477:Fluprednisolone; C015808:difluprednate