title: [Good outcome in Acanthamoeba keratitis].
abstract: A 31-year-old woman presented with mild keratitis of her left eye. The use of daily disposable contact lenses, regularly rinsed with tap water, and the development of perineural corneal infiltrates resulted in the clinical suspicion of infection with Acanthamoeba. Corneal epithelial scraping probe for polymerase chain reaction on Acanthamoeba confirmed the clinical diagnosis. Although the treatment was limited to low-dose propamidine monotherapy because of reduced tolerability, the keratitis healed with almost no scarring after 13 months of consequent medication.
authors: Abteilung für Augenheilkunde, Akademisches Lehrkrankenhaus Feldkirch, Carinagasse 47, 6800, Feldkirch, Österreich. Silvia.Peter@Lkhf.at.
authors: S
authors: S
authors: Reichart-Peter
authors: Abteilung für Augenheilkunde, Akademisches Lehrkrankenhaus Feldkirch, Carinagasse 47, 6800, Feldkirch, Österreich.
authors: K
authors: K
authors: Manousaridis
authors: Institut für Pathologie, Akademisches Lehrkrankenhaus Feldkirch, Feldkirch, Österreich.
authors: H
authors: H
authors: Dirschmid
authors: Abteilung für Augenheilkunde, Akademisches Lehrkrankenhaus Feldkirch, Carinagasse 47, 6800, Feldkirch, Österreich.
authors: S
authors: S
authors: Mennel
mesh_terms: D015823:Acanthamoeba Keratitis / Q000175:diagnosis / Q000188:drug therapy*; D000328:Adult; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D001550:Benzamidines / Q000009:adverse effects / Q000627:therapeutic use*; D001645:Biguanides / Q000009:adverse effects / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000981:Antiprotozoal Agents; D001550:Benzamidines; D001645:Biguanides; C031233:polihexanide; C046651:propamidine isethionate
keywords: Acanthamoeba; Keratitis; Polyhexamethylene biguanide; Propamidine isethionate; Radial keratoneuritis