title: [Multifocal tuberculosis in immunocompetent patients].
abstract: Multifocal tuberculosis is defined as the presence of lesions affecting at least two extrapulmonary sites, with or without pulmonary involvement. This retrospective study of 10 cases aims to investigate the clinical and evolutionary characteristics of multifocal tuberculosis. It included 41 cases with tuberculosis collected between 1999 and 2013. Ten patients had multifocal tuberculosis (24%): 9 women and 1 man, the average age was 50 years (30-68 years). Our patients were correctly BCG vaccinated. The evaluation of immunodepression was negative in all patients. 7 cases had lymph node tuberculosis, 3 cases digestive tuberculosis, 2 cases pericardial tuberculosis, 2 cases osteoarticular tuberculosis, 1 case brain tuberculosis, 2 cases urinary tuberculosis, 4 cases urogenital tuberculosis, 1 case adrenal tuberculosis, 1 case cutaneous and 1 case muscle tuberculosis. All patients received anti-tuberculosis treatment for a mean duration of 10 months, with good evolution. Multifocal tuberculosis is difficult to diagnose. It can affect immunocompetent patients but often has good prognosis. Anti-tuberculosis therapy must be initiated as soon as possible to avoid sequelae.
authors: Service de Médecine Interne, CHU Sahloul, Sousse, Tunisie.
authors: Amel
authors: A
authors: Rezgui
authors: Service de Médecine Interne, CHU Sahloul, Sousse, Tunisie.
authors: Fatma Ben
authors: FB
authors: Fredj
authors: Service de Médecine Interne, CHU Sahloul, Sousse, Tunisie.
authors: Anis
authors: A
authors: Mzabi
authors: Service de Médecine Interne, CHU Sahloul, Sousse, Tunisie.
authors: Monia
authors: M
authors: Karmani
authors: Service de Médecine Interne, CHU Sahloul, Sousse, Tunisie.
authors: Chadia
authors: C
authors: Laouani
mesh_terms: D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome; D014376:Tuberculosis / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology
chemical_list: D000995:Antitubercular Agents; D001500:BCG Vaccine
keywords: Multifocal tuberculosis; immunocompetent; lung damage