title: Can mean platelet volume and red blood cell distribution width show disease activity in rheumatoid arthritis?
abstract: OBJECTIVE
  To evaluate the relationship between mean platelet volume (MPV) and red cell distribution width (RDW), and disease activity in rheumatoid arthritis (RA).
  
  
  METHODS
  Hundred RA and 100 controls were included.
  
  
  RESULTS
  MPV and RDW were higher in RA (p < 0.0001). The cut-off levels of RDW and MPV were 14.8 and 10.4. Patients with RDW >14.8 had higher Disease Activity Score 28 (DAS28; p = 0.002) and pain score (p = 0.0007). RDW was positively correlated with DAS28 and pain. But, DAS28 and pain were not different between patients with MPV >10.4 and <10.4.
  
  
  CONCLUSIONS
  MPV and RDW were significantly higher in RA. RDW and MPV were similar to erythrocyte sedimentation rate and C-reactive protein to indicate inflammatory activity. RDW was correlated with pain and DAS28, but MPV was not associated with them.
authors: Department of Physical Medicine & Rehabilitation, Division of Rheumatology, Gazi University Medical Faculty, Ankara, Turkey.
authors: Duygu
authors: D
authors: Tecer
authors: Department of Physical Medicine & Rehabilitation Mersin, Mersin University Medical Faculty, Mersin, Turkey.
authors: Melek
authors: M
authors: Sezgin
authors: Department of Biostatistics & Medical Informatics, Mersin University Medical Faculty, Mersin, Turkey.
authors: Arzu
authors: A
authors: Kanık
authors: Department of Physical Medicine & Rehabilitation Mersin, Mersin University Medical Faculty, Mersin, Turkey.
authors: Nurgül Arıncı
authors: NA
authors: İncel
authors: Department of Physical Medicine & Rehabilitation Mersin, Mersin University Medical Faculty, Mersin, Turkey.
authors: Özlem Bölgen
authors: ÖB
authors: Çimen
authors: Department of Physical Medicine & Rehabilitation Mersin, Mersin University Medical Faculty, Mersin, Turkey.
authors: Ali
authors: A
authors: Biçer
authors: Department of Physical Medicine & Rehabilitation Mersin, Mersin University Medical Faculty, Mersin, Turkey.
authors: Günşah
authors: G
authors: Şahin
mesh_terms: D000368:Aged; D019540:Area Under Curve; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000473:pathology*; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets / Q000166:cytology* / Q000502:physiology; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D016022:Case-Control Studies; D004909:Erythrocyte Indices; D004912:Erythrocytes / Q000166:cytology* / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D012372:ROC Curve; D012189:Retrospective Studies; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein
keywords: C-reactive protein; Disease Activity Score 28; erythrocyte sedimentation rate; mean platelet volume; red cell distribution width; rheumatoid arthritis