title: Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach.
abstract: The aim of the study was to report the clinical utility of optical coherence tomography angiography (OCT-A) in characterizing and differentiating inflammatory lesions and choroidal neovascularization (CNV) in multifocal choroiditis (MFC). A patient affected by MFC complaining central visual loss and scotoma in his left eye was fully investigated with dye-based angiographies, structural OCT and OCT-A. A reactivation of macular CNV was initially suspected, while OCT-A revealed the absence of any decorrelation signal both over the retinal pigment epithelium (RPE) and between RPE and Bruchs' membrane. OCT-A is a promising tool in detecting inflammatory CNV and in differentiating CNV from primitive inflammatory damage. Finely characterizing the aspect of a lesion allows us to choose the best therapeutic strategy for managing these potentially blinding diseases.
authors: Section of Ophthalmology, Department of Biomedical and Surgical Sciences, S. Maria della Misericordia Hospital, University of Perugia, 06156, Perugia, Italy. cerquagliaalessio@gmail.com.
authors: Alessio
authors: http://orcid.org/0000-0003-2765-0639
authors: A
authors: Cerquaglia
authors: Section of Ophthalmology, Department of Biomedical and Surgical Sciences, S. Maria della Misericordia Hospital, University of Perugia, 06156, Perugia, Italy.|Centre de l'Odéon, 113 Boulevard St Germain, 75006, Paris, France.
authors: Marco
authors: M
authors: Lupidi
authors: Section of Ophthalmology, Department of Biomedical and Surgical Sciences, S. Maria della Misericordia Hospital, University of Perugia, 06156, Perugia, Italy.
authors: Tito
authors: T
authors: Fiore
authors: Section of Ophthalmology, Department of Biomedical and Surgical Sciences, S. Maria della Misericordia Hospital, University of Perugia, 06156, Perugia, Italy.
authors: Barbara
authors: B
authors: Iaccheri
authors: Division of Ophthalmology, Department of Biomedical and Surgical Sciences, University of Ferrara, Ferrara, Italy.
authors: Paolo
authors: P
authors: Perri
authors: Section of Ophthalmology, Department of Biomedical and Surgical Sciences, S. Maria della Misericordia Hospital, University of Perugia, 06156, Perugia, Italy.
authors: Carlo
authors: C
authors: Cagini
mesh_terms: D016570:Bruch Membrane / Q000473:pathology; D002829:Choroid / Q000473:pathology*; D020256:Choroidal Neovascularization / Q000175:diagnosis* / Q000209:etiology; D002833:Choroiditis / Q000150:complications / Q000175:diagnosis*; D005451:Fluorescein Angiography / Q000379:methods*; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D000080364:Multifocal Choroiditis; D012165:Retinal Ganglion Cells / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity
keywords: Inflammatory choroidal neovascularization; Multifocal choroiditis; Optical coherence tomography angiography; Uveitis