title: No Evidence of Rat Hepatitis E Virus Excretion in Urine Samples of Rats.
abstract: To investigate whether rat hepatitis E virus (rat HEV) is excreted in the urine of HEV-infected rats, we infected 3 Wistar and 6 nude rats with rat HEV and examined the rat-HEV RNA in serum, fecal, and urine samples. We detected rat-HEV RNA in the serum and fecal samples of all 9 rats but not in any of the urine samples. Our results suggest that in rats, rat HEV is not transmitted via urine.
authors: Department of Virology II, National Institute of Infectious Diseases.
authors: Tian-Cheng
authors: TC
authors: Li
authors: Department of Virology II, National Institute of Infectious Diseases.
authors: Sayaka
authors: S
authors: Yoshizaki
authors: Division of Experimental Animals Research, National Institute of Infectious Diseases.
authors: Yasushi
authors: Y
authors: Ami
authors: Division of Experimental Animals Research, National Institute of Infectious Diseases.
authors: Yuriko
authors: Y
authors: Suzaki
authors: Federal Institute for Risk Assessment.
authors: Reimar
authors: R
authors: Johne
authors: Department of Virology II, National Institute of Infectious Diseases.
authors: Takaji
authors: T
authors: Wakita
mesh_terms: D000818:Animals; D005243:Feces / Q000821:virology; D016751:Hepatitis E / Q000662:veterinary*; D016752:Hepatitis E virus / Q000302:isolation & purification*; D006801:Humans; D011923:Rats, Nude; D017208:Rats, Wistar; D044967:Serum / Q000821:virology; D014556:Urine / Q000821:virology*; D017201:Virus Shedding
keywords: hepatitis E virus; rat; rat HEV; urine