title: Electrochemiluminescence aptasensor of TiO2/CdS:Mn hybrids for ultrasensitive detection of cytochrome c.
abstract: A novel electrochemiluminescence (ECL) aptasensor was proposed for ultrasensitive detection of cytochrome c (cyt c) using CdS:Mn quantum dot-modified TiO2 nanowires (NWs) as electrode. The Mn-doped CdS was deposited on the TiO2 NWs by successive ion layer adsorption and reaction (SILAR) as ECL emitter, on which thiol-modified aptamer of cyt c was attached via Cd-S bond. Due to the high photo-electrical transfer efficiency, the as-prepared aptasensor shows high selectivity and sensitivity towards cyt c with a detection limit of 9.5fM and a linear range from 50fM to 125pM.
authors: State Key Lab of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082 China.
authors: Na
authors: N
authors: Bin
authors: State Key Lab of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082 China.
authors: Weili
authors: W
authors: Li
authors: State Key Lab of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082 China.
authors: Xuehua
authors: X
authors: Yin
authors: State Key Lab of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082 China.
authors: Xiaohua
authors: X
authors: Huang
authors: State Key Lab of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082 China. Electronic address: qycai0001@hnu.edu.cn.
authors: Qingyun
authors: Q
authors: Cai
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques; D019187:Cadmium Compounds / Q000737:chemistry*; D045304:Cytochromes c / Q000032:analysis* / Q000737:chemistry; D055664:Electrochemical Techniques; D008163:Luminescent Measurements; D008345:Manganese / Q000737:chemistry*; D053770:Nanowires / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry*; D018036:Selenium Compounds / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry*
chemical_list: D052157:Aptamers, Nucleotide; D019187:Cadmium Compounds; D018036:Selenium Compounds; C009495:titanium dioxide; D008345:Manganese; D045304:Cytochromes c; C058667:cadmium selenide; D014025:Titanium
keywords: CdS:Mn quantum dots; Cytochrome c; Electrochemiluminescence aptasensor; Titanium dioxide nanowires