title: In Vitro Comparison of Five Different Elastography Systems for Clinical Applications, Using Strain and Shear Wave Technology.
abstract: Several different platforms providing ultrasound elastography have emerged in recent years. In this in vitro study on a single tissue-mimicking phantom (CIRS Model 49), we aimed to compare the performance of quantitative elastography measurements from platforms running strain elastography and others running shear wave elastography. We evaluated five different elastography platforms using both linear and curvilinear probes. All measurements were performed in parallel by two independent investigators who recorded the elasticity quantitatively. We investigated intra- and inter-observer agreement by intra-class correlation analysis and coefficient of variation, by correlation and limits of agreement. The reproducibility of elasticity measurements was good to excellent for shear wave and strain elastography. All five elastography platforms had high intra-observer (intra-class correlation coefficient: 0.932-1.0) and inter-observer correlation (intra-class correlation coefficient: 0.845-0.996). All inclusions could be differentiated by quantitative elastography by all systems (p < 0.001). The use of a linear probe yielded more reproducible measurements compared with use of a convex probe in 3/4 platforms.
authors: National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital, N-5021 Bergen, Norway; Institute of Clinical Medicine, University of Bergen, N-5020, Bergen, Norway.
authors: Anesa
authors: A
authors: Mulabecirovic
authors: National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital, N-5021 Bergen, Norway; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Cancer Medicine, Surgery and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.
authors: Mette
authors: M
authors: Vesterhus
authors: National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital, N-5021 Bergen, Norway; Institute of Clinical Medicine, University of Bergen, N-5020, Bergen, Norway.
authors: Odd Helge
authors: OH
authors: Gilja
authors: National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital, N-5021 Bergen, Norway. Electronic address: roald.flesland.havre@helse-bergen.no.
authors: Roald Flesland
authors: RF
authors: Havre
mesh_terms: D055119:Elastic Modulus; D004548:Elasticity; D054459:Elasticity Imaging Techniques / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D066298:In Vitro Techniques; D015588:Observer Variation; D019047:Phantoms, Imaging; D015203:Reproducibility of Results
keywords: Phantom; Shear wave imaging; Strain imaging; Ultrasound elastography