title: Herbal medicines and nonalcoholic fatty liver disease.
abstract: Nonalcoholic fatty liver disease (NAFLD), which is characterized by excessive fat accumulation in the liver of patients who consume little or no alcohol, becomes increasingly common with rapid economic development. Long-term excess fat accumulation leads to NAFLD and represents a global health problem with no effective therapeutic approach. NAFLD is considered to be a series of complex, multifaceted pathological processes involving oxidative stress, inflammation, apoptosis, and metabolism. Over the past decades, herbal medicines have garnered growing attention as potential therapeutic agents to prevent and treat NAFLD, due to their high efficacy and low risk of side effects. In this review, we evaluate the use of herbal medicines (including traditional Chinese herbal formulas, crude extracts from medicinal plants, and pure natural products) to treat NAFLD. These herbal medicines are natural resources that can inform innovative drug research and the development of treatments for NAFLD in the future.
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Hong
authors: H
authors: Yao
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Yu-Jie
authors: YJ
authors: Qiao
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Ya-Li
authors: YL
authors: Zhao
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Xu-Feng
authors: XF
authors: Tao
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Li-Na
authors: LN
authors: Xu
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Lian-Hong
authors: LH
authors: Yin
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Yan
authors: Y
authors: Qi
authors: Hong Yao, Yu-Jie Qiao, Ya-Li Zhao, Xu-Feng Tao, Li-Na Xu, Lian-Hong Yin, Yan Qi, Jin-Yong Peng, College of Pharmacy, Dalian Medical University, Dalian 116044, Liaoning Province, China.
authors: Jin-Yong
authors: JY
authors: Peng
mesh_terms: D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005419:Flavonoids / Q000627:therapeutic use; D029001:Herbal Medicine; D006801:Humans; D008516:Medicine, Chinese Traditional; D065626:Non-alcoholic Fatty Liver Disease / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D012503:Saponins / Q000627:therapeutic use
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010936:Plant Extracts; D012503:Saponins
keywords: Herbal medicines; Natural product; Nonalcoholic fatty liver disease; Review; Traditional Chinese medicines