title: Detection of New Delhi Metallo-Beta-Lactamase (Encoded by blaNDM-1) in Enterobacter aerogenes in China.
abstract: BACKGROUND
  The increase in blaNDM-1in Enterobacteriaceae has become a major concern worldwide. In previous study, we investigated clonal dissemination and mechanisms of resistance to carbapenem in China.
  
  
  METHODS
  We carried out retrospective surveillance for blaNDM-1among carbapenem-resistant enterobacter strains, which were isolated from patients at our hospital by bacterial strains selection, antimicrobial susceptibility testing, species identification, and molecular detection of resistance gene.
  
  
  RESULTS
  We found three blaNDM-1-positive isolates which were identified as Enterobacter aerogenes in clinical patients in China. The blaNDM-1-positive Enterobacter aerogenes isolates were first found.
  
  
  CONCLUSIONS
  It is important to mandate prudent usage of antibiotics and implement infection control measures to control the spread of these resistant blaNDM-1-positive strains.
authors: Department of Clinical Laboratory, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan, China.
authors: Yong
authors: Y
authors: Shen
authors: Department of Clinical Laboratory, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan, China.
authors: Wei-Qiang
authors: WQ
authors: Xiao
authors: Department of Clinical Laboratory, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
authors: Jiao-Mei
authors: JM
authors: Gong
authors: Department of Clinical Laboratory, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan, China.
authors: Jun
authors: J
authors: Pan
authors: Department of Clinical Laboratory, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, Henan, China.
authors: Qing-Xia
authors: QX
authors: Xu
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics*; D015780:Carbapenems / Q000494:pharmacology*; D002681:China; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D021902:Enterobacter aerogenes / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D015780:Carbapenems; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1; C063912:carbapenemase
keywords: 
  bla
  
  NDM
  
  -1
  ; 
  enterobacter aerogenes
  ; New Delhi metallo-Beta-Lactamase; resistance