title: Radiofrequency Ablation in the Sinus of Valsalva for Ventricular Arrhythmia in Pediatric Patients.
abstract: The need to perform catheter ablation of ventricular arrhythmia from within the sinuses of Valsalva in a pediatric patient is uncommon. This has been reported in adults, but there are little data about the feasibility, safety or efficacy of catheter ablation in the sinuses of Valsalva in the pediatric patients. This is a retrospective review of all patients aged 18 years or less, at two separate institutions with no structural heart disease that underwent an ablation procedure for ventricular arrhythmia mapped to the sinus of Valsalva from 2010 to 2015. We identified 8 total patients meeting inclusion criteria. Median age was 16 years and the median weight was 61 kg. All patients were symptomatic or had developed arrhythmia-induced ventricular dysfunction. Ablation was performed in the left sinus in 4 patients and the right sinus in 4 patients. No ablations were required in the non-coronary sinus. All 8 patients had an acutely successful ablation using radiofrequency energy. There were no complications. At a mean follow-up of 7 months (4-15 months), all patients were known to be living. Follow-up data regarding arrhythmia were available in 6 of the 8 patients, and none had recurrence of their ventricular arrhythmia off of all antiarrhythmic medications. Radiofrequency catheter ablation of ventricular arrhythmia in the sinus of Valsalva can be done safely and effectively in pediatric patients.
authors: Mayo Clinic Rochester, Rochester, MN, USA. wackel.philip@mayo.edu.
authors: Philip L
authors: PL
authors: Wackel
authors: Duke University Medical Center, Durham, NC, USA.
authors: Andrew W
authors: AW
authors: McCrary
authors: Duke University Medical Center, Durham, NC, USA.
authors: Salim F
authors: SF
authors: Idriss
authors: Mayo Clinic Rochester, Rochester, MN, USA.
authors: Samuel J
authors: SJ
authors: Asirvatham
authors: Mayo Clinic Rochester, Rochester, MN, USA.
authors: Bryan C
authors: BC
authors: Cannon
mesh_terms: D000293:Adolescent; D017115:Catheter Ablation; D004562:Electrocardiography; D006801:Humans; D012189:Retrospective Studies; D012850:Sinus of Valsalva; D017180:Tachycardia, Ventricular
keywords: Aortic cusp; Catheter ablation; Pediatric; Premature ventricular contraction; Sinus of Valsalva; Ventricular tachycardia