title: Gold-Catalyzed Tandem 1,3-Migration/Double Cyclopropanation of 1-Ene-4,n-diyne Esters to Tetracyclodecene and Tetracycloundecene Derivatives.
abstract: A synthetic method that relies on Au(I)-catalyzed tandem 1,3-acyloxy migration/double cyclopropanation of 1-ene-4,9-diyne and 1-ene-4,10-diyne esters to construct the respective architecturally challenging tetracyclodecene and tetracycloundecene derivatives is described. Achieved under mild reaction conditions, the transformation was shown to be robust with a wide variety of substitution patterns tolerated to give the two members of the carbocyclic family in good to excellent yields and as a single regio- and diastereomer.
authors: Jiangsu Key Laboratory of Biomass-based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University , Nanjing 210037, China.
authors: Cuili
authors: C
authors: Chen
authors: Jiangsu Key Laboratory of Biomass-based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University , Nanjing 210037, China.
authors: Yongzhen
authors: Y
authors: Zou
authors: Jiangsu Key Laboratory of Biomass-based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University , Nanjing 210037, China.
authors: Xianxiao
authors: X
authors: Chen
authors: Jiangsu Key Laboratory of Biomass-based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University , Nanjing 210037, China.
authors: Xiaoxiang
authors: X
authors: Zhang
authors: Jiangsu Key Laboratory of Biomass-based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University , Nanjing 210037, China.
authors: Weidong
authors: W
authors: Rao
authors: School of Chemistry, Monash University , Clayton, Victoria 3800, Australia.|Department of Chemistry, University of Warwick , Coventry, CV4 7AL, United Kingdom.
authors: Philip Wai Hong
authors: PW
authors: Chan