title: Associated bare stenting of distal aorta with a Djumbodis(®) system versus conventional surgery in type A aortic dissection.
abstract: BACKGROUND
  The effectiveness of additional stenting of the distal aorta as compared to conventional surgery alone in type A aortic dissection (TAD) has yet to be proven.
  
  
  METHODS
  We conducted this multicenter comparative study to evaluate the effects of antegrade bare stenting of the dissected aorta beyond the distal anastomosis with a Djumbodis(®) device system (DDS). Outcomes that were measured included early outcomes, overall mortality from aortic cause and late aortic events including re-interventions. A consecutive series of 134 patients operated on in two participating centers were distributed into study and control groups according to the treatment received: conventional surgery with DDS (DJ group, n=42) or without (control group, n=92).
  
  
  RESULTS
  Operative mortality was 21.4% and 17.6% in the DJ and control groups, respectively (P=0.9), and was within pre-specified alarm lines for both groups. In multivariate analysis, the only independent predictor of operative mortality was the presence of any complication (cardiac tamponade or malperfusion, P=0.05), which occurred more in the DJ group (OR =1.3; non-significant). Sixty patients were included into the matched survivors cohorts study (propensity scoring). The aortic event-free survival at 7 years for early survivors was 77%±10% and 48%±11% in the matched DJ group and control group, respectively (HR =0.66). Late mortality from an aortic cause was 10% and 20% in the matched DJ group and control group, respectively (RR =0.5). Actuarial freedom from aortic or vascular interventions was 71%±10% and 67%±9% in the matched DJ and control group, respectively. Operative mortality was not influenced by the use of DDS as compared to conventional surgery alone for TAD.
  
  
  CONCLUSIONS
  We observed a trend towards better organ perfusion in the DJ group postoperatively, and more aortic events and deaths of aortic cause in the control group during follow-up.
authors: University Hospital Amiens, Amiens, France ;
authors: Thierry
authors: T
authors: Caus
authors: Novosibirsk Research Institute of Circulation Pathology, Novosibirsk, Russia.
authors: Dmitry
authors: D
authors: Sirota
authors: University Hospital Amiens, Amiens, France ;
authors: Joseph
authors: J
authors: Nader
authors: Novosibirsk Research Institute of Circulation Pathology, Novosibirsk, Russia.
authors: Maxim
authors: M
authors: Lyashenko
authors: Novosibirsk Research Institute of Circulation Pathology, Novosibirsk, Russia.
authors: Alexander
authors: A
authors: Chernyavsky
keywords: CUSUM; Djumbodis system; Type A aortic dissection; comparative study; propensity score