title: Laparoscopic left lateral sectionectomy in patients with histologically confirmed cirrhosis.
abstract: BACKGROUND
  Laparoscopic left lateral sectionectomy (LLS) is now considered as a standard practice. However, the safety of laparoscopic LLS in cirrhotic patients is unclear. This is the retrospective study of comparing the outcomes of laparoscopic LLS between cirrhotic and non-cirrhotic patients.
  
  
  METHODS
  We reviewed the clinical data for 107 patients who underwent laparoscopic LLS between July 2003 and July 2013. The patients were divided into cirrhotic group (n = 31) and non-cirrhotic group (n = 76) with histologically confirmed F4 or F3 fibrosis.
  
  
  RESULTS
  There were no differences between the two groups in terms of the operation time (P = 0.807), blood loss (P = 0.115), transfusion rate (P = 0.716), postoperative complication rate (P = 0.601) and duration of hospital stay (P = 0.261). Open conversion occurred in one non-cirrhotic patient (P = 1.000). The postoperative peak total bilirubin level was higher in cirrhotic patients than in non-cirrhotic patients (P < 0.001). Among patients with hepatocellular carcinoma, the disease-free survival (P = 0.249) and overall survival (P = 0.768) rates were not significantly different between cirrhotic patients (n = 28) and non-cirrhotic patients (n = 12). There were no significant differences in the complication rate (P = 0.085), operation time (P = 0.159), blood loss (P = 0.306), transfusion rate (P = 1.00), and hospital day (P = 0.408) between laparoscopic LLS and cases of open LLS performed in the same study period (n = 10).
  
  
  CONCLUSIONS
  Laparoscopic LLS is safe and reproducible, even in cirrhotic patients.
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Chami
authors: C
authors: Im
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea. Electronic address: jychogs@gmail.com.
authors: Jai Young
authors: JY
authors: Cho
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Ho-Seong
authors: HS
authors: Han
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Yoo-Seok
authors: YS
authors: Yoon
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: YoungRok
authors: Y
authors: Choi
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Jae Yool
authors: JY
authors: Jang
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Hanlim
authors: H
authors: Choi
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Jae Seong
authors: JS
authors: Jang
authors: Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Seong Uk
authors: SU
authors: Kwon
authors: Department of Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
authors: Haeryoung
authors: H
authors: Kim
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay; D008103:Liver Cirrhosis / Q000209:etiology / Q000601:surgery*; D008113:Liver Neoplasms / Q000150:complications* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D015996:Survival Rate