title: Contribution of diffusion-weighted MR imaging in follow-up of inflammatory appendiceal mass: Preliminary results and review of the literature.
abstract: OBJECTIVE
  We aimed to search the contribution of diffusion-weighted imaging (DWI) in follow-up of patients with acute appendicitis associated inflammatory appendiceal mass (IAM). DWI was used as a monitoring imaging method to assess the response of medical treatment.
  
  
  METHODS
  19 patients (mean age, 37+-13.1; age range, 19-69; M/F: 10/9), presented with clinical, laboratory and computed tomography (CT) findings suggestive of IAM were enrolled prospectively in this study. CT and DWI images were evaluated by two radiologists in consensus. b values 0, 500 and 1000 s/mm(2) were used, and DWI images were analysed both qualitatively and quantitatively. Laboratory parameters were C-reactive protein value and white blood cell count. During follow-up changes in the diameter of IMA and laboratory parameters were correlated with ADC values. Conservative treatment with interval appendectomy and a total conservative approach without surgery were the treatment options during follow-up.
  
  
  RESULTS
  We found statistically significant correlation between the ADC values, maximum IAM diameter and laboratory parameters. During follow-up five surgical procedures were performed: one patient underwent surgery for cecal adenocarcinoma and four underwent interval appendectomy. One patient developed acute relapse of IAM at the sixth month of follow-up.
  
  
  CONCLUSIONS
  DWI may be used with a significant success for follow-up of patients with IAM. As a monitoring imaging method, DWI may also aid in determining of most appropriate timing for interval appendectomy as well as may help in diagnosing alternative diagnoses (e.g. malignancy and inflammatory bowel disease) that can mimic IAM.
authors: Recep Tayyip Erdoğan University, Faculty of Medicine, Department of Radiology, 53100, Rize, Turkey.
authors: Oğuzhan
authors: O
authors: Özdemir
authors: Recep Tayyip Erdoğan University, Faculty of Medicine, Department of Radiology, 53100, Rize, Turkey.
authors: Yavuz
authors: Y
authors: Metin
authors: Recep Tayyip Erdoğan University, Faculty of Medicine, Department of Radiology, 53100, Rize, Turkey.
authors: Nurgül Orhan
authors: NO
authors: Metin
authors: Muş State Hospital, Department of Radiology, 49000, Muş, Turkey.
authors: Ali
authors: A
authors: Küpeli
authors: Recep Tayyip Erdoğan University, Faculty of Medicine, Department of General Surgery, 53100, Rize, Turkey.
authors: Süleyman
authors: S
authors: Kalcan
authors: Recep Tayyip Erdoğan University, Faculty of Medicine, Department of Radiology, 53100, Rize, Turkey.
authors: Filiz
authors: F
authors: Taşçı
keywords: Diffusion-weighted imaging; Inflammatory appendiceal mass