title: A Population-Based Assessment of the Agreement Between Grading of Goniophotographic Images and Gonioscopy in the Chinese-American Eye Study (CHES).
abstract: OBJECTIVE
  To compare grading of goniophotographic images and gonioscopy in assessing the iridocorneal angle.
  
  
  METHODS
  In a population-based, cross-sectional study, participants underwent gonioscopy and goniophotographic imaging during the same visit. The iridocorneal angle was classified as closed if the posterior trabecular meshwork could not be seen. A single masked observer graded the goniophotographic images, and each eye was classified as having angle closure based on the number of closed quadrants. Agreement between the methods was analyzed by calculating kappa (κ) and first-order agreement coefficient (AC1) statistics and comparison of area under receiver operating characteristic curves (AUC).
  
  
  RESULTS
  A total of 4149 Chinese Americans (3994 eyes) were included in this study. The agreement for angle closure diagnosis between gonioscopy and EyeCam was moderate to excellent (κ = 0.60, AC1 0.90, AUC 0.76-0.80).
  
  
  CONCLUSIONS
  Detection of iridocorneal angle closure based on goniophotographic imaging shows moderate to very good agreement with angle closure assessment using gonioscopy.
authors: University of Southern California Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States 2University of California, San Francisco, Department of Ophthalmology, San Francisco, California, United States.
authors: Yohko
authors: Y
authors: Murakami
authors: University of Southern California Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
authors: Dandan
authors: D
authors: Wang
authors: University of Southern California Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
authors: Bruce
authors: B
authors: Burkemper
authors: University of California, San Francisco, Department of Ophthalmology, San Francisco, California, United States.
authors: Shan C
authors: SC
authors: Lin
authors: University of Southern California Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
authors: Rohit
authors: R
authors: Varma
mesh_terms: D001213:Asian; D002140:California / Q000453:epidemiology; D003315:Cornea / Q000473:pathology; D003430:Cross-Sectional Studies; D005500:Follow-Up Studies; D005901:Glaucoma / Q000175:diagnosis* / Q000208:ethnology / Q000503:physiopathology; D006068:Gonioscopy / Q000379:methods*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D007498:Iris / Q000473:pathology; D010781:Photography / Q000379:methods*; D011159:Population Surveillance; D011446:Prospective Studies; D012372:ROC Curve; D018570:Risk Assessment / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*