title: Fission yeast septation.
abstract: In animal cells cytokinesis relies on the contraction of an actomyosin ring that pulls the plasma membrane to create a cleavage furrow, whose ingression finally divides the mother cell into two daughter cells. Fungal cells are surrounded by a tough and flexible structure called cell wall, which is considered to be the functional equivalent of the extracellular matrix in animal cells. Therefore, in addition to cleavage furrow ingression, fungal cytokinesis also requires the centripetal formation of a septum wall structure that develops between the dividing cells, whose genesis must be strictly coordinated with both the actomyosin ring closure and plasma membrane ingression. Here we briefly review what is known about the septum structure and composition in the fission yeast Schizosaccharomyces pombe, the recent progress about the relationship between septum biosynthesis and actomyosin ring constriction, and the importance of the septum and ring in the steady progression of the cleavage furrow.
authors: Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca , Salamanca, Spain.
authors: Juan C G
authors: JC
authors: Cortés
authors: Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca , Salamanca, Spain.
authors: Mariona
authors: M
authors: Ramos
authors: Faculty of Science, Laboratory of Electron Microscopy, Japan Women's University, Tokyo, Japan; Integrated Imaging Research Support, Tokyo, Japan.
authors: Masako
authors: M
authors: Osumi
authors: Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca , Salamanca, Spain.
authors: Pilar
authors: P
authors: Pérez
authors: Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas (CSIC)/Universidad de Salamanca , Salamanca, Spain.
authors: Juan Carlos
authors: JC
authors: Ribas
keywords: cell wall; cleavage furrow; contractile actomyosin ring; cytokinesis; glucan; septum