title: Risk factors for recurrence of borderline ovarian tumours: A tertiary centre experience.
abstract: The aim of this study was to evaluate the risk factors for recurrence of borderline ovarian tumours. This study investigated 127 women who were finally diagnosed with borderline epithelial ovarian tumours. Most of them were diagnosed in stage I (83.4%). With a median follow-up of 81.8 months (range: 14-205), the median time to recurrence was 22.4 months (range: 3-74). Five-year recurrence-free survival (RFS) and overall survival (OS) rates were 85.8% and 97.6%, respectively. In multivariate analysis, invasive implants and fertility-sparing surgery were found to be independent prognostic factors for 5-year RFS. Overall, 20 patients (15.7%) experienced relapse within the observation period. Although there is no consensus about high-risk category of borderline ovarian tumours, invasive implants and conservative surgery were closely related to the recurrence. Patients presenting these risk factors should undergo closer follow-up.
authors: a Department of Obstetrics and Gynecology, Division of Gynecologic Oncology , Cerrahpasa Faculty of Medicine, Istanbul University , Istanbul , Turkey.
authors: Fuat
authors: F
authors: Demirkiran
authors: a Department of Obstetrics and Gynecology, Division of Gynecologic Oncology , Cerrahpasa Faculty of Medicine, Istanbul University , Istanbul , Turkey.
authors: Veysel
authors: V
authors: Sal
authors: a Department of Obstetrics and Gynecology, Division of Gynecologic Oncology , Cerrahpasa Faculty of Medicine, Istanbul University , Istanbul , Turkey.
authors: Tugan
authors: T
authors: Bese
authors: a Department of Obstetrics and Gynecology, Division of Gynecologic Oncology , Cerrahpasa Faculty of Medicine, Istanbul University , Istanbul , Turkey.
authors: Nedim
authors: N
authors: Tokgozoglu
authors: b Department of Obstetrics and Gynecology , Sisli Hamidiye Etfal Training and Research Hospital , Istanbul , Turkey.
authors: Hakan
authors: H
authors: Erenel
authors: a Department of Obstetrics and Gynecology, Division of Gynecologic Oncology , Cerrahpasa Faculty of Medicine, Istanbul University , Istanbul , Turkey.
authors: Nigar
authors: N
authors: Sofiyeva
authors: a Department of Obstetrics and Gynecology, Division of Gynecologic Oncology , Cerrahpasa Faculty of Medicine, Istanbul University , Istanbul , Turkey.
authors: Ilker
authors: I
authors: Kahramanoglu
authors: a Department of Obstetrics and Gynecology, Division of Gynecologic Oncology , Cerrahpasa Faculty of Medicine, Istanbul University , Istanbul , Turkey.
authors: Macit
authors: M
authors: Arvas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local / Q000209:etiology* / Q000401:mortality; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D062606:Tertiary Care Centers; D055815:Young Adult
keywords: Borderline; ovarian; prognostic factors; recurrence; surgery