title: Negative pressure wound therapy combined with skin grafting improves surgical wound healing in the perianal area.
abstract: Management of large tissue defects resulting from local wide resection of perianal is a clinical challenge for surgeons. The aim of the present study was to investigate the efficacy of negative pressure wound therapy (NPWT) following skin grafting on perianal surgical wound healing.Included in this study were 12 patients with perianal tumors who received skin grafting after perianal tumor resection between December 2012 and December 2014. A self-designed negative pressure drainage device was then applied to maintain a standard negative pressure at -150 mm Hg and removed on day 8 postoperation. The outcome was recorded immediately after NPWT and at 6-month follow-up.All skin grafts survived without infection, hematoma, and necrosis in all 12 patients. No tumor recurrence was detected during 6-month follow-up. Natural folds were observed around the anus. All patients showed normal bowel movements.NPWT following skin grafting was effective for perianal surgical wound healing and infection prevention, thus benefiting anatomical and functional recovery of the anus.
authors: Graduate Management Unit, Second Military Medical University Graduate Management Unit, Second Military Medical University Department of Plastic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
authors: Shi
authors: S
authors: Jia-Zi
authors: Zhai
authors: Z
authors: Xiao
authors: Li
authors: L
authors: Jun-Hui
authors: Xue
authors: X
authors: Chun-Yu
authors: Bi
authors: B
authors: Hong-da
mesh_terms: D001003:Anal Canal / Q000601:surgery*; D001005:Anus Neoplasms / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy; D016038:Skin Transplantation; D000072836:Surgical Wound / Q000503:physiopathology*; D014945:Wound Healing