title: Breast Cancer in a 19-Year-Old Female Adolescent Identified with Li-Fraumeni Syndrome.
abstract: BACKGROUND
  Breast cancer is rare in adolescents. In one study, breast carcinoma accounted for 0.02% of breast masses surgically removed in young women. We report a case of breast cancer in a 19-year-old woman who was found to have Li-Fraumeni Syndrome.
  
  
  METHODS
  The patient presented with a new, hard, nonmobile lump in the right breast which prompted her to seek medical attention. A biopsy identified invasive ductal carcinoma. Genetic testing showed a p53 mutation associated with Li-Fraumeni syndrome.
  
  
  CONCLUSIONS
  Although breast masses in young women are mostly benign, one must entertain the possibility of more serious conditions when a breast mass is identified with concerning medical or physical findings. Genetic testing might be informative for such patients.
authors: St. John Hospital, Grosse Pointe, Michigan. Electronic address: allyjcyprus@hotmail.com.
authors: Allison M
authors: AM
authors: Jay
authors: St. John Hospital, Grosse Pointe, Michigan.
authors: Anthony S
authors: AS
authors: Hamame
authors: St. John Hospital, Grosse Pointe, Michigan.
authors: Carrie
authors: C
authors: Dul
authors: St. John Hospital, Grosse Pointe, Michigan.
authors: Cheryl
authors: C
authors: Wesen
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics*; D018270:Carcinoma, Ductal, Breast / Q000235:genetics*; D005260:Female; D006801:Humans; D016864:Li-Fraumeni Syndrome / Q000235:genetics*; D016159:Tumor Suppressor Protein p53; D055815:Young Adult
chemical_list: D016159:Tumor Suppressor Protein p53
keywords: Breast cancer; Li-Fraumeni syndrome; Ultrasound; Young age