title: Quercus ilex L.: How season, Plant Organ and Extraction Procedure Can Influence Chemistry and Bioactivities.
abstract: Quercus species have a plethora of applications, either in wine and wood industries, in human and animal nutrition or in human health. In order to improve the knowledge on this genus, the aim of the present study was to correlate, for the first time, the phenolic composition of different Quercus ilex L. plant tissues (leaves in two maturation stages, acorns, teguments and cotyledons) and different extraction procedures with scavenging and anticholinesterase activities. The hydromethanolic and aqueous extracts obtained showed strong radical scavenging activity against DPPH, superoxide anion radical and nitric oxide radical, leaves exhibiting higher total phenolic content and revealing the best antioxidant properties, followed by tegument and acorns. Concerning the phenolic profile, fifteen compounds were identified and quantified by HPLC-DAD, ranging from 1568.43 to 45,803.16 mg/kg dried extract. The results indicate that Q. ilex can be a source of strong antioxidant phenolic compounds with possible interest for food and pharmaceutical industries.
authors: Department of Physico-Chemical Biology, Faculty of Nature and Life Sciences, University of Bejaia, Bejaia, 06000, Algeria.
authors: Lila
authors: L
authors: Hadidi
authors: Department of Food Science, Faculty of Nature and Life Sciences, University of Bejaia, Bejaia, 06000, Algeria.
authors: Louiza
authors: L
authors: Babou
authors: Department of Food Science, Faculty of Nature and Life Sciences, University of Bejaia, Bejaia, 06000, Algeria.
authors: Farid
authors: F
authors: Zaidi
authors: REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, no. 228, PT-4050-313, Porto, Portugal.
authors: Patrícia
authors: P
authors: Valentão
authors: REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, no. 228, PT-4050-313, Porto, Portugal.
authors: Paula B
authors: PB
authors: Andrade
authors: REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, no. 228, PT-4050-313, Porto, Portugal.
authors: Clara
authors: C
authors: Grosso
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D008722:Methods; D010636:Phenols / Q000302:isolation & purification* / Q000494:pharmacology; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D029963:Quercus / Q000737:chemistry*; D012621:Seasons
chemical_list: D000975:Antioxidants; D010636:Phenols; D010936:Plant Extracts
keywords: Cholinesterase inhibition; HPLC-DAD; Phenolic profile; Quercus ilex L.; Scavenging activity