title: Enantioselective Construction of Spirocyclic Oxindoles via Tandem Michael/Michael Reactions Catalyzed by Multifunctional Quaternary Phosphonium Salt.
abstract: The enantioselective construction of five-membered spirocyclic oxindoles via a double Michael cascade reaction is described by using dipeptide-based multifunctional quaternary phosphonium salt catalysts. The desired products were obtained in excellent yields (up to 94%) and good to high stereoselectivities (up to >19:1 dr and 99% ee).
authors: The Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University , Wuhu, Anhui 241000, China.
authors: Jiaxing
authors: J
authors: Zhang
authors: Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors: Dongdong
authors: D
authors: Cao
authors: Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors: Hongyu
authors: H
authors: Wang
authors: Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors: Changwu
authors: C
authors: Zheng
authors: Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors: Gang
authors: G
authors: Zhao
authors: The Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University , Wuhu, Anhui 241000, China.
authors: Yongjia
authors: Y
authors: Shang