title: High-intensity interval training reduces abdominal fat mass in postmenopausal women with type 2 diabetes.
abstract: OBJECTIVE
  This study compared the effect of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) for 16 weeks on whole-body and abdominal fat mass (FM) in postmenopausal women with type 2 diabetes (T2D).
  
  
  METHODS
  Seventeen women (69±1 years; BMI: 31±1kg.m-2) were randomly assigned to either a HIIT [60×(8s at 77-85% HRmax, 12s of active recovery)] or MICT (40min at 55-60% of their individual HRR) cycling program for 16 weeks, 2 days/week. Dual-energy X-ray absorptiometry was used to measure whole-body and regional FM content, including abdominal adiposity and visceral adipose tissue. Plasma cholesterol, HDL, LDL, triglycerides, glucose and HbA1clevels were measured. Levels of nutritional intake and physical activity were evaluated by 7-day self-reports.
  
  
  RESULTS
  Dietary energy (caloric) intake, physical activity level and total body mass did not vary in either group from the beginning to the end of the training intervention. Overall, total FM decreased and total fat-free mass significantly increased over time (by around 2-3%). Total FM reduction at the end of the intervention was not significantly different between groups. However, significant loss of total abdominal (-8.3±2.2%) and visceral (-24.2±7.7%) FM was observed only with HIIT. Time effects were noted for HbA1cand total cholesterol/HDL ratio.
  
  
  CONCLUSIONS
  With no concomitant caloric restriction, an HIIT program in postmenopausal women with T2D (twice a week for 16 weeks) appeared to be more effective for reducing central obesity than MICT, and could be proposed as an alternative exercise training program for this population.
authors: Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological condition (AME2P), Blaise-Pascal University, EA 3533, 63000 Clermont-Ferrand, France.
authors: F
authors: F
authors: Maillard
authors: INRA, Human Nutrition Unit UMR1019, Clermont-Ferrand, France; CRNH-Auvergne, 63000 Clermont-Ferrand, France.
authors: S
authors: S
authors: Rousset
authors: University Hospital Clermont-Ferrand, Biostatistics Unit (DRCI), 63000 Clermont-Ferrand, France.
authors: B
authors: B
authors: Pereira
authors: INRA, QuaPA - UR 0370, plateforme de Résonance Magnétique des Systèmes Biologiques (RMSB), 63122 Saint-Genes-Champanelle, France.
authors: A
authors: A
authors: Traore
authors: Scanner-IRM 63, 63000 Clermont-Ferrand, France.
authors: P
authors: P
authors: de Pradel Del Amaze
authors: INRA, Human Nutrition Unit UMR1019, Clermont-Ferrand, France; Department of Human Nutrition, Clermont-Ferrand University Hospital, G.-Montpied Hospital, 63000 Clermont-Ferrand, France; UFR Medicine, University Clermont 1, 63000 Clermont-Ferrand, France; CRNH-Auvergne, 63000 Clermont-Ferrand, France.
authors: Y
authors: Y
authors: Boirie
authors: INRA, Human Nutrition Unit UMR1019, Clermont-Ferrand, France; UFR Medicine, University Clermont 1, 63000 Clermont-Ferrand, France; CRNH-Auvergne, 63000 Clermont-Ferrand, France; Department of Sport Medicine and Functional Explorations, Clermont-Ferrand University Hospital, G.-Montpied Hospital, 63000 Clermont-Ferrand, France.
authors: M
authors: M
authors: Duclos
authors: Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological condition (AME2P), Blaise-Pascal University, EA 3533, 63000 Clermont-Ferrand, France; CRNH-Auvergne, 63000 Clermont-Ferrand, France. Electronic address: Nathalie.BOISSEAU@univ-bpclermont.fr.
authors: N
authors: N
authors: Boisseau
mesh_terms: D050153:Abdominal Fat / Q000502:physiology*; D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition / Q000502:physiology; D003924:Diabetes Mellitus, Type 2 / Q000628:therapy*; D005260:Female; D000072696:High-Intensity Interval Training; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000502:physiology*
keywords: Body composition; Health; Menopause; Physical activity; Type 2 diabetes