title: Asymmetric synthesis using chiral-encoded metal.
abstract: The synthesis of chiral compounds is of crucial importance in many areas of society and science, including medicine, biology, chemistry, biotechnology and agriculture. Thus, there is a fundamental interest in developing new approaches for the selective production of enantiomers. Here we report the use of mesoporous metal structures with encoded geometric chiral information for inducing asymmetry in the electrochemical synthesis of mandelic acid as a model molecule. The chiral-encoded mesoporous metal, obtained by the electrochemical reduction of platinum salts in the presence of a liquid crystal phase and the chiral template molecule, perfectly retains the chiral information after removal of the template. Starting from a prochiral compound we demonstrate enantiomeric excess of the (R)-enantiomer when using (R)-imprinted electrodes and vice versa for the (S)-imprinted ones. Moreover, changing the amount of chiral cavities in the material allows tuning the enantioselectivity.
authors: Univ. Bordeaux, CNRS UMR 5255, Bordeaux INP, ENSCBP, 16 Avenue Pey Berland, 33607 Pessac, France.|Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.|NANOTEC Center for Nanoscale Materials Design for Green Nanotechnology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.|Department of Chemical and Biomolecular Engineering, School of Energy Science and Engineering, Vidyasirimedhi Institute of Science and Technology, Rayong 21210, Thailand.
authors: Thittaya
authors: T
authors: Yutthalekha
authors: Department of Chemical and Biomolecular Engineering, School of Energy Science and Engineering, Vidyasirimedhi Institute of Science and Technology, Rayong 21210, Thailand.
authors: Chularat
authors: C
authors: Wattanakit
authors: Univ. Bordeaux, CNRS UMR 5255, Bordeaux INP, ENSCBP, 16 Avenue Pey Berland, 33607 Pessac, France.
authors: Veronique
authors: V
authors: Lapeyre
authors: Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.|NANOTEC Center for Nanoscale Materials Design for Green Nanotechnology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
authors: Somkiat
authors: S
authors: Nokbin
authors: Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.|NANOTEC Center for Nanoscale Materials Design for Green Nanotechnology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
authors: Chompunuch
authors: C
authors: Warakulwit
authors: Department of Materials Science and Engineering, School of Molecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology, Rayong 21210, Thailand.
authors: Jumras
authors: J
authors: Limtrakul
authors: Univ. Bordeaux, CNRS UMR 5255, Bordeaux INP, ENSCBP, 16 Avenue Pey Berland, 33607 Pessac, France.
authors: Alexander
authors: A
authors: Kuhn