title: Green synthesis of silver nanoparticles using Salvadora persica L. and its antibacterial activity.
abstract: The silver nanoparticles (AgNPs) shows special physicochemical properties, therefore they use many applications such as catalysis, health, electronic and optical. In this study, AgNPs was synthesized using aqueous extract of Salvadora persica bark. The synthesized AgNPs were characterized by UV-Vis spectroscopy, Powder X-ray diffraction (PXRD) and Transmission electron microscopy (TEM) methods. The optimal synthesis condition to prepare nanoparticles was determined as silver nitrate 3 mM, 5 ml of aqueous extract in the room temperature for 1 h. The TEM image of AgNPs showed the formation of spherical, non-uniform nanoparticles of mean size of 50 nm. The antibacterial activity of synthesized AgNPs was evaluated using disk diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods on Escherichia coli and Staphylococcus aureus bacteria. The MIC values of AgNPs were 100 and 400 µg/mL on E. coli and S. aureus, respectively. Also the MBC of AgNPs was 200 µg/mL for E. coli and there was no result observed for S. aureus bacteria. The results showed that synthesized nanoparticles have favorable antibacterial properties.
authors: Zabol University of Medical Sciences Department of Pharmacognosy, Faculty of Pharmacy Zabol Iran.
authors: A
authors: A
authors: Miri
authors: Zabol University of Medical Sciences Department of Pharmacognosy, Faculty of Pharmacy Zabol Iran.
authors: N
authors: N
authors: Dorani
authors: Mashhad University of Medical Sciences Nuclear Medicine Research Center Mashhad Iran.
authors: M
authors: M
authors: Darroudi
authors: Zabol University of Medical Sciences Department of Pharmacognosy, Faculty of Pharmacy Zabol Iran minasarani64@gmail.com.
authors: M
authors: M
authors: Sarani
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D055772:Green Chemistry Technology; D053768:Metal Nanoparticles / Q000737:chemistry / Q000633:toxicity* / Q000648:ultrastructure; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D010316:Particle Size; D010936:Plant Extracts / Q000737:chemistry; D032121:Salvadoraceae / Q000737:chemistry* / Q000378:metabolism; D012834:Silver / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013211:Staphylococcus aureus / Q000187:drug effects*; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D012834:Silver