title: NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors.
authors: Children's Cancer Research Institute, Vienna, Austria.
authors: K
authors: K
authors: Byrgazov
authors: Children's Cancer Research Institute, Vienna, Austria.
authors: R
authors: R
authors: Kastner
authors: CeMM, Research Center for Molecular Medicine of the Austrian Academy of Science, Vienna, Austria.
authors: M
authors: M
authors: Gorna
authors: Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
authors: G
authors: G
authors: Hoermann
authors: Children's Cancer Research Institute, Vienna, Austria.
authors: M
authors: M
authors: Koenig
authors: Children's Cancer Research Institute, Vienna, Austria.
authors: C B
authors: CB
authors: Lucini
authors: Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
authors: R
authors: R
authors: Ulreich
authors: Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
authors: M
authors: M
authors: Benesch
authors: Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
authors: V
authors: V
authors: Strenger
authors: Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
authors: H
authors: H
authors: Lackner
authors: Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
authors: W
authors: W
authors: Schwinger
authors: Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
authors: P
authors: P
authors: Sovinz
authors: Children's Cancer Research Institute, Vienna, Austria.
authors: O A
authors: OA
authors: Haas
authors: Department of Pediatric Hemato-Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.|Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
authors: M
authors: M
authors: van den Heuvel-Eibrink
authors: Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany.
authors: C M
authors: CM
authors: Niemeyer
authors: Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
authors: O
authors: O
authors: Hantschel
authors: Division of Hematology and Hemostaseology, Department of Internal Medicine, Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
authors: P
authors: P
authors: Valent
authors: CeMM, Research Center for Molecular Medicine of the Austrian Academy of Science, Vienna, Austria.
authors: G
authors: G
authors: Superti-Furga
authors: Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
authors: C
authors: C
authors: Urban
authors: Children's Cancer Research Institute, Vienna, Austria.|St Anna Children's Hospital, Vienna, Austria.
authors: M N
authors: MN
authors: Dworzak
authors: Children's Cancer Research Institute, Vienna, Austria.|Department of Pediatrics, Medical University of Vienna, Vienna, Austria.
authors: T
authors: T
authors: Lion
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000235:genetics; D002460:Cell Line; D019008:Drug Resistance, Neoplasm; D004802:Eosinophilia / Q000150:complications*; D006801:Humans; D007223:Infant; D051379:Mice; D009154:Mutation; D009196:Myeloproliferative Disorders / Q000150:complications / Q000188:drug therapy* / Q000235:genetics; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D011487:Protein Conformation; D047428:Protein Kinase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors; D020797:Receptor, Platelet-Derived Growth Factor beta / Q000737:chemistry / Q000235:genetics*; D017422:Sequence Analysis, DNA; D014161:Transduction, Genetic
chemical_list: D002352:Carrier Proteins; C421108:NDEL1 protein, human; C000622896:NDEL1-PDGFRB oncogene fusion protein, human; D015514:Oncogene Proteins, Fusion; D047428:Protein Kinase Inhibitors; C000605860:PDGFRB protein, human; D011505:Protein-Tyrosine Kinases; D020797:Receptor, Platelet-Derived Growth Factor beta