title: Determination of Inorganic Ion Profiles of Illicit Drugs by Capillary Electrophoresis.
abstract: A portable capillary electrophoresis instrument with dual capacitively coupled contactless conductivity detection (C4D) was used to determine the inorganic ionic profiles of three pharmaceutical samples and precursors of two illicit drugs (contemporary samples of methylone and para-methoxymethamphetamine). The LODs ranged from 0.10 μmol/L to 1.25 μmol/L for the 10 selected cations, and from 0.13 μmol/L to 1.03 μmol/L for the eight selected anions. All separations were performed in less than 6 min with migration times and peak area RSD values ranging from 2 to 7%. The results demonstrate the potential of the analysis of inorganic ionic species to aid in the identification and/or differentiation of unknown tablets, and real samples found in illicit drug manufacture scenarios. From the resulting ionic fingerprint, the unknown tablets and samples can be further classified.
authors: Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249.
authors: Elizabeth
authors: E
authors: Evans
authors: Departmento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
authors: Carolina
authors: C
authors: Costrino
authors: Departmento de Química Fundamental, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
authors: Claudimir L
authors: http://orcid.org/0000-0003-1542-4343
authors: CL
authors: do Lago
authors: Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249.
authors: Carlos D
authors: CD
authors: Garcia
authors: Centre for Forensic Science, University of Technology, Sydney, Broadway, NSW,2001, NSW, Australia.
authors: Claude
authors: C
authors: Roux
authors: Centre for Forensic Science, University of Technology, Sydney, Broadway, NSW,2001, NSW, Australia.
authors: Lucas
authors: L
authors: Blanes
mesh_terms: D004553:Electric Conductivity; D019075:Electrophoresis, Capillary; D013287:Illicit Drugs / Q000032:analysis*; D013607:Tablets
chemical_list: D013287:Illicit Drugs; D013607:Tablets
keywords: C4D; capillary electrophoresis; contactless conductivity detection; forensic science; illicit drugs; ion analysis