title: Comparison of microsatellite distribution in genomes of Centruroides exilicauda and Mesobuthus martensii.
abstract: In this study, we characterized the distribution of microsatellites in the genomes and genes of Centruroides exilicauda and Mesobuthus martensii, carried out Gene Ontology (GO) analysis and GO enrichment analysis of coding sequences (CDSs) with microsatellite (SSR). In addition, over-represented GO functions related to environmental interactions, development process and methylation were identified to develop functional markers and facilitate further analysis of microsatellite function in the genes of scorpions. Location analysis indicated that microsatellites were predominantly concentrated at both ends of genes. Most genes containing microsatellite had the SSR present at only one locus, from which we infer that the number of SSRs per gene is limited even though intragenic tandem repeats can generate functional variability. Lastly, we identified 75 SSRs in 64 genes of 54 expanded gene families and 1 SSR in the toxin gene of Mesobuthus martensii, allowing future studies on the effect of microsatellites on gene function.
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China.
authors: Chen
authors: C
authors: Wang
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China.
authors: Lukasz Jakub
authors: LJ
authors: Kubiak
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China.
authors: Lian-Ming
authors: LM
authors: Du
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China.
authors: Wu-Jiao
authors: WJ
authors: Li
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China.
authors: Zuo-Yi
authors: ZY
authors: Jian
authors: Sichuan Key Laboratory of Medical American cockroach, Chengdu 610041, PR China.
authors: Ce
authors: C
authors: Tang
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China.
authors: Zhen-Xin
authors: ZX
authors: Fan
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China.
authors: Xiu-Yue
authors: XY
authors: Zhang
authors: Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, PR China. Electronic address: bsyue@scu.edu.cn.
authors: Bi-Song
authors: BS
authors: Yue
mesh_terms: D000818:Animals; D016678:Genome; D018895:Microsatellite Repeats; D012605:Scorpions / Q000235:genetics*; D013045:Species Specificity
keywords: Functional annotation; Microsatellite distribution; Scorpions; Simple sequence repeats