title: Reliability and Construct Validity of the Patient-Reported Outcomes Measurement Information System (PROMIS) Instruments in Women with Fibromyalgia.
abstract: OBJECTIVE
  The Patient-Reported Outcomes Measurement Information System (PROMIS) was developed to standardize measurement of clinically relevant patient-reported outcomes. This study evaluated the reliability and construct validity of select PROMIS static short-form (SF) instruments in women with fibromyalgia.
  
  
  METHODS
  Analysis of baseline data from the Fibromyalgia Activity Study with TENS (FAST), a randomized controlled trial of the efficacy of transcutaneous electrical nerve stimulation.
  
  
  METHODS
  Dual site, university-based outpatient clinics.
  
  
  METHODS
  Women aged 20 to 67 years diagnosed with fibromyalgia.
  
  
  METHODS
  Participants completed the Revised Fibromyalgia Impact Questionnaire (FIQR) and 10 PROMIS static SF instruments. Internal consistency was calculated using Cronbach alpha. Convergent validity was examined against the FIQR using Pearson correlation and multiple regression analysis.
  
  
  RESULTS
  PROMIS static SF instruments had fair to high internal consistency (Cronbach α = 0.58 to 0.94, P  < 0.05). PROMIS 'physical function' domain score was highly correlated with FIQR 'function' score (r = -0.73). The PROMIS 'total' score was highly correlated with the FIQR total score (r = -0.72). Correlations with FIQR total score of each of the three PROMIS domain scores were r = -0.65 for 'physical function,' r = -0.63 for 'global,' and r = -0.57 for 'symptom' domain. PROMIS 'physical function,' 'global,' and 'symptom' scores explained 58% of the FIQR total score variance.
  
  
  CONCLUSIONS
  Select PROMIS static SF instruments demonstrate convergent validity with the FIQR, a legacy measure of fibromyalgia disease severity. These results highlight the potential utility of select PROMIS static SFs for assessment and tracking of patient-reported outcomes in fibromyalgia.
authors: Department of Physical Therapy and Rehabilitation Science.
authors: Ericka N
authors: EN
authors: Merriwether
authors: College of Nursing.
authors: Barbara A
authors: BA
authors: Rakel
authors: College of Public Health, University of Iowa, Iowa City, Iowa.
authors: Miriam B
authors: MB
authors: Zimmerman
authors: Department of Physical Therapy and Rehabilitation Science.
authors: Dana L
authors: DL
authors: Dailey
authors: Department of Physical Therapy and Rehabilitation Science.
authors: Carol G T
authors: CGT
authors: Vance
authors: Department of Medicine/Rheumatology & Immunology, Vanderbilt University, Nashville, Tennessee, USA.
authors: Leon
authors: L
authors: Darghosian
authors: Department of Medicine/Rheumatology & Immunology, Vanderbilt University, Nashville, Tennessee, USA.
authors: Meenakshi
authors: M
authors: Golchha
authors: Department of Physical Therapy and Rehabilitation Science.
authors: Katherine M
authors: KM
authors: Geasland
authors: Department of Physical Therapy and Rehabilitation Science.
authors: Ruth
authors: R
authors: Chimenti
authors: Department of Medicine/Rheumatology & Immunology, Vanderbilt University, Nashville, Tennessee, USA.
authors: Leslie J
authors: LJ
authors: Crofford
authors: Department of Physical Therapy and Rehabilitation Science.|College of Nursing.
authors: Kathleen A
authors: KA
authors: Sluka
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005356:Fibromyalgia / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D000071066:Patient Reported Outcome Measures; D015203:Reproducibility of Results; D004561:Transcutaneous Electric Nerve Stimulation; D016896:Treatment Outcome; D055815:Young Adult
keywords: Fibromyalgia; PROMIS; Pain; Psychometrics