title: Lokiarchaeon is hydrogen dependent.
abstract: The nature of the host that acquired the mitochondrion at the eukaryote origin is an important microbial evolutionary issue. Modern phylogenetics indicates that the host was an archaeon. The metagenome sequence of Candidatus Lokiarchaeon has identified it as being the closest relative of the host yet known. Here, we report comparative genomic evidence indicating that Lokiarchaeon is hydrogen dependent, as one theory for the eukaryote origin-the hydrogen hypothesis-predicts for the host lineage.
authors: Institute of Molecular Evolution, Heinrich-Heine University, 40225 Düsseldorf, Germany.
authors: Filipa L
authors: FL
authors: Sousa
authors: Institute of Molecular Evolution, Heinrich-Heine University, 40225 Düsseldorf, Germany.
authors: Sinje
authors: S
authors: Neukirchen
authors: Research Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK.
authors: John F
authors: http://orcid.org/0000-0002-0950-0429
authors: JF
authors: Allen
authors: Research Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK.
authors: Nick
authors: N
authors: Lane
authors: Institute of Molecular Evolution, Heinrich-Heine University, 40225 Düsseldorf, Germany.
authors: William F
authors: WF
authors: Martin
mesh_terms: D001105:Archaea / Q000235:genetics* / Q000378:metabolism*; D019295:Computational Biology; D023281:Genomics; D006859:Hydrogen / Q000378:metabolism*; D053858:Metabolic Networks and Pathways / Q000235:genetics*
chemical_list: D006859:Hydrogen