title: Trends in Gout and Rheumatoid Arthritis Hospitalizations in Canada From 2000 to 2011.
abstract: Gout and rheumatoid arthritis (RA) are the 2 most common forms of inflammatory arthritis worldwide. As hospitalizations for both conditions lead to substantial health resource use, contemporary inpatient trends and associated costs may provide important benchmarks of disease burden. However, relevant data are limited.
  
  
  
  We used PopulationData BC, a population-based administrative data set from Canada. We examined trends in the annual hospitalization and surgery rate of gout and RA from 2000 to 2011. Additionally, we examined annual trends in the inpatient cost burden of both conditions. We assessed annual trends in hospitalization and surgery rates using Poisson regression models and cost trends using linear regression models.
  
  
  
  From 2000 to 2011, the annual hospitalization rate for RA declined by 49% from 15.4 to 7.9 per 100,000 Canadian adults (P < 0.001), whereas that for gout doubled from 3.8 to 7.6 per 100,000 Canadian adults (P < 0.001). Approximately 31% of RA admissions were associated with hip or knee replacement surgery; the trend of these surgeries paralleled the declining trend in RA hospitalizations (P = 0.0097). The inpatient costs also reflected the hospitalization trends, with a 40% decrease in RA hospital costs, while gout costs more than doubled over the study period.
  
  
  
  Our findings indicate that hospitalization rates for gout have doubled over the past decade, while those for RA have decreased considerably. While these data provide an encouraging benchmark for RA care, they also highlight the critical need to improve gout management and prevention to mitigate its rising disease burden in Canada and beyond.
authors: Arthritis Research Canada and University of British Columbia, Vancouver, British Columbia, Canada.
authors: Sharan K
authors: SK
authors: Rai
authors: Arthritis Research Canada and University of British Columbia, Vancouver, British Columbia, Canada.
authors: J Antonio
authors: JA
authors: Aviña-Zubieta
authors: Arthritis Research Canada and University of British Columbia, Vancouver, British Columbia, Canada.
authors: Natalie
authors: N
authors: McCormick
authors: Arthritis Research Canada and University of British Columbia, Vancouver, British Columbia, Canada.
authors: Mary A
authors: MA
authors: De Vera
authors: Arthritis Research Canada and University of British Columbia, Vancouver, British Columbia, Canada.
authors: Diane
authors: D
authors: Lacaille
authors: Arthritis Research Canada, Vancouver, British Columbia, Canada.
authors: Eric C
authors: EC
authors: Sayre
authors: Arthritis Research Canada, Vancouver, British Columbia, Canada, and Massachusetts General Hospital and Harvard Medical School, Boston.
authors: Hyon K
authors: HK
authors: Choi
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000191:economics*; D001955:British Columbia / Q000453:epidemiology; D017281:Cost of Illness; D005260:Female; D006073:Gout / Q000191:economics / Q000453:epidemiology*; D017721:Hospital Costs / Q000639:trends*; D006760:Hospitalization / Q000191:economics / Q000706:statistics & numerical data* / Q000639:trends; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D016012:Poisson Distribution