title: [Radiotherapy for retroperitoneal sarcomas].
abstract: The management of retroperitoneal sarcoma can be very challenging, and the quality of initial treatment strategy appears to be a crucial prognostic factor. En bloc surgery is currently the standard of care for these rare tumours and perioperative treatments such as chemotherapy or radiotherapy have not been validated yet. However, local-regional relapse constitutes the most common disease course. While adjuvant radiotherapy is less and less common due to gastrointestinal toxicities, preoperative radiation therapy offers numerous advantages and is being evaluated as part of a national multicentre phase II study (TOMOREP trial) and is the subject of a European randomized phase III study (STRASS trial). The objective of this article is to present data on preoperative irradiation in terms of dose, volumes and optimal radiotherapy techniques for the treatment of this rare disease.
authors: Département de radiothérapie, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France. Electronic address: p.sargos@bordeaux.unicancer.fr.
authors: P
authors: P
authors: Sargos
authors: Département de chirurgie, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.
authors: E
authors: E
authors: Stoeckle
authors: Département de radiothérapie, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.
authors: B
authors: B
authors: Henriques de Figueiredo
authors: Unité de physique médicale, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.
authors: M
authors: M
authors: Antoine
authors: Département de radiothérapie, institut Claudius-Regaud, 1, avenue Irène-Joliot-Curie, 31059 Toulouse cedex 9, France.
authors: M
authors: M
authors: Delannes
authors: Département de radiothérapie, institut de cancérologie de l'Ouest René-Gauducheau, boulevard Jacques-Monod, 44805 Saint-Herblain, France.
authors: A
authors: A
authors: Mervoyer
authors: Département de radiothérapie, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux cedex, France.
authors: G
authors: G
authors: Kantor
mesh_terms: D006801:Humans; D000072662:Margins of Excision; D020360:Neoadjuvant Therapy; D058958:Organs at Risk; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D061089:Radiotherapy, Image-Guided; D050397:Radiotherapy, Intensity-Modulated; D012186:Retroperitoneal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D012509:Sarcoma / Q000532:radiotherapy* / Q000601:surgery
keywords: Chirurgie; Intensity-modulated radiation therapy (IMRT); Radiotherapy; Radiothérapie; Radiothérapie conformationelle en modulation d’intensité (RCMI); Retroperitoneal sarcoma; Sarcome rétropéritonéaux; Surgery