title: Nickel-Catalyzed Reductive Couplings.
abstract: The Ni-catalyzed reductive coupling of alkyl/aryl with other electrophiles has evolved to be an important protocol for the construction of C-C bonds. This chapter first emphasizes the recent progress on the Ni-catalyzed alkylation, arylation/vinylation, and acylation of alkyl electrophiles. A brief overview of CO2 fixation is also addressed. The chemoselectivity between the electrophiles and the reactivity of the alkyl substrates will be detailed on the basis of different Ni-catalyzed conditions and mechanistic perspective. The asymmetric formation of C(sp(3))-C(sp(2)) bonds arising from activated alkyl halides is next depicted followed by allylic carbonylation. Finally, the coupling of aryl halides with other C(sp(2))-electrophiles is detailed at the end of this chapter.
authors: Department of Chemistry, Center for Supramolecular Materials and Catalysis, Shanghai University, 99 Shang-Da Road, Shanghai, 200444, China.
authors: Xuan
authors: X
authors: Wang
authors: Department of Chemistry, Center for Supramolecular Materials and Catalysis, Shanghai University, 99 Shang-Da Road, Shanghai, 200444, China.
authors: Yijing
authors: Y
authors: Dai
authors: Department of Chemistry, Center for Supramolecular Materials and Catalysis, Shanghai University, 99 Shang-Da Road, Shanghai, 200444, China. hegui_gong@shu.edu.cn.|Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, 200092, China. hegui_gong@shu.edu.cn.
authors: Hegui
authors: H
authors: Gong
keywords: Electrophiles; Nickel catalysis; Reductive coupling; Selectivity