title: Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
abstract: Our results confirmed the more aggressive behavior of PSRCC compared to MBC. This tumor is frequently associated with more frequent lymphatic metastasis, higher Ki67 labeling index, more advanced stage disease as well as simultaneous vimentin upregulation and E-cadherin downregulation. Different management guidelines should be considered for the two types.
authors: Department of Surgery, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Xiufeng
authors: X
authors: Wu
authors: Department of Pathology, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Zhenzhen
authors: Z
authors: Zhang
authors: Fujian Institute of Hematology, Union Hospital, Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Xin
authors: X
authors: Li
authors: Department of Surgery, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Qingzhong
authors: Q
authors: Lin
authors: Department of Pathology, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Gang
authors: G
authors: Chen
authors: Department of Pathology, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Jianping
authors: J
authors: Lu
authors: Department of Surgery, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Yi
authors: Y
authors: Zeng
authors: Department of Pathology, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Dan
authors: D
authors: Hu
authors: Department of Surgery, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Kai
authors: K
authors: Huang
authors: Department of Surgery, Fujian Provincial Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.
authors: Zhiwu
authors: Z
authors: Lin
authors: Department of Surgery, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014, Fujian, People's Republic of China.|Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P.R. China.
authors: Jun
authors: J
authors: Yan
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000378:metabolism* / Q000473:pathology; D018279:Carcinoma, Signet Ring Cell / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D058750:Epithelial-Mesenchymal Transition; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism*; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D009077:Mucins