title: Brain temperature could affect neurochemical evaluations.
abstract: This article demonstrates the importance of natural brain temperature fluctuations as a critical factor affecting electrochemical detection of extracellular glutamate in awake rats and proposes a viable strategy to exclude this inescapable influence, thereby increasing the reliability of electrochemical measurements of glutamate in behaving animals.
authors: In-Vivo Electrophysiology Unit; Behavioral Neuroscience Branch; National Institute on Drug Abuse - Intramural Research Program; National Institutes of Health; Baltimore, MD USA.
authors: Eugene A
authors: EA
authors: Kiyatkin
keywords: brain temperature; electrochemistry; enzymatic reactions; enzyme-based biosensors; glucose; glutamate