title: Potent Activities of Novel Imidazoles Lanoconazole and Luliconazole against a Collection of Azole-Resistant and -Susceptible Aspergillus fumigatus Strains.
abstract: A collection of azole-susceptible (n = 141) and azole-resistant (n = 27) Aspergillus fumigatus isolates was tested against seven antifungal drugs, including the new imidazoles lanoconazole and luliconazole. The luliconazole and lanoconazole MIC90values for the azole-susceptible strains were 0.001 μg/ml and 0.008 μg/ml, and those for the azole-resistant strains were 0.016 μg/ml and 0.032 μg/ml.
authors: Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors: Mahdi
authors: M
authors: Abastabar
authors: Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
authors: Nooshin
authors: N
authors: Rahimi
authors: Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.|Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
authors: Jacques F
authors: 0000-0003-3253-6080
authors: JF
authors: Meis
authors: Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
authors: Narges
authors: N
authors: Aslani
authors: Department of Medical Mycology and Parasitology, Tehran University of Medical Science, Tehran, Iran.
authors: Sadegh
authors: S
authors: Khodavaisy
authors: Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors: Mojtaba
authors: M
authors: Nabili
authors: Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors: Ali
authors: A
authors: Rezaei-Matehkolaei
authors: Laboratory of Space and Environmental Medicine, Graduate School of Medicine, Teikyo University, Japan/Asia International Institute of Infectious Diseases Control, Teikyo University, and Teikyo University Institute of Medical Mycology, Tokyo, Japan.
authors: Koichi
authors: K
authors: Makimura
authors: Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran badalii@yahoo.com.|Department of Medical Mycology and Parasitology, Mazandaran University of Medical Sciences, Sari, Iran.
authors: Hamid
authors: 0000-0002-6010-8414
authors: H
authors: Badali
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001232:Aspergillus fumigatus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D001393:Azoles / Q000494:pharmacology; D025141:Drug Resistance, Fungal / Q000187:drug effects*; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
chemical_list: D000935:Antifungal Agents; D001393:Azoles; D007093:Imidazoles; C072774:latoconazole; C112528:luliconazole