title: mTORC2 Puts Its Shoulder to Krebs' Wheel.
abstract: In this issue of Molecular Cell, Moloughney et al. (2016) find that mTORC2 responds to falling levels of glucose and glutamine catabolites, promoting glutaminolysis and preserving the TCA cycle and hexosamine biosynthesis.
authors: Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA.
authors: Sebastian I
authors: SI
authors: Arriola Apelo
authors: Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA. Electronic address: dlamming@medicine.wisc.edu.
authors: Dudley W
authors: DW
authors: Lamming
mesh_terms: D005973:Glutamine; D006801:Humans; D000076225:Mechanistic Target of Rapamycin Complex 2; D046912:Multiprotein Complexes; D012782:Shoulder; D058570:TOR Serine-Threonine Kinases
chemical_list: D046912:Multiprotein Complexes; D005973:Glutamine; D000076225:Mechanistic Target of Rapamycin Complex 2; D058570:TOR Serine-Threonine Kinases