title: One-pot synthesis of (-)-Ambrox.
abstract: (-)-Ambrox is recognised as the prototype of all ambergris odorants. Widely used in perfumery, (-)-Ambrox is an important ingredient due to its unique scent and excellent fixative function. An environmentally friendly and practical preparation of (-)-Ambrox is still unavailable at present although a lot of attention has been paid to this hot research topic for many years. A one-pot synthesis of (-)-Ambrox was studied starting from (-)-sclareol through oxidation with hydrogen peroxide in the presence of a quaternary ammonium phosphomolybdate catalyst {[C5H5NC16H33] [H2PMo12O40]}, which gave the product a 20% overall yield.
authors: Beijing Innovation Centre of Food Nutrition and Human Health, Beijing Key laboratory of Flavour Chemistry, Beijing Technology and Business University, No. 11 Fucheng Road, Haidian District, Beijing 100048, P.R. China.
authors: Shaoxiang
authors: S
authors: Yang
authors: Beijing Innovation Centre of Food Nutrition and Human Health, Beijing Key laboratory of Flavour Chemistry, Beijing Technology and Business University, No. 11 Fucheng Road, Haidian District, Beijing 100048, P.R. China.
authors: Hongyu
authors: H
authors: Tian
authors: Beijing Innovation Centre of Food Nutrition and Human Health, Beijing Key laboratory of Flavour Chemistry, Beijing Technology and Business University, No. 11 Fucheng Road, Haidian District, Beijing 100048, P.R. China.
authors: Baoguo
authors: B
authors: Sun
authors: Beijing Innovation Centre of Food Nutrition and Human Health, Beijing Key laboratory of Flavour Chemistry, Beijing Technology and Business University, No. 11 Fucheng Road, Haidian District, Beijing 100048, P.R. China.
authors: Yongguo
authors: Y
authors: Liu
authors: Beijing Innovation Centre of Food Nutrition and Human Health, Beijing Key laboratory of Flavour Chemistry, Beijing Technology and Business University, No. 11 Fucheng Road, Haidian District, Beijing 100048, P.R. China.
authors: Yanfeng
authors: Y
authors: Hao
authors: Beijing Innovation Centre of Food Nutrition and Human Health, Beijing Key laboratory of Flavour Chemistry, Beijing Technology and Business University, No. 11 Fucheng Road, Haidian District, Beijing 100048, P.R. China.
authors: Yanyu
authors: Y
authors: Lv
mesh_terms: D018648:Ambergris / Q000737:chemistry*; D064751:Ammonium Compounds / Q000737:chemistry; D004224:Diterpenes / Q000737:chemistry; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D006861:Hydrogen Peroxide / Q000737:chemistry; D008982:Molybdenum / Q000737:chemistry; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry; D009812:Odorants; D010756:Phosphoric Acids / Q000737:chemistry
chemical_list: D018648:Ambergris; D064751:Ammonium Compounds; D004224:Diterpenes; D005663:Furans; D009281:Naphthalenes; D010756:Phosphoric Acids; C413580:ambrox; D008982:Molybdenum; C070760:sclareol; D006861:Hydrogen Peroxide; C003125:phosphomolybdic acid