title: Nine things to know about elicitins.
abstract: 888 I. 888 II. 889 III. 889 IV. 889 V. 891 VI. 891 VII. 891 VIII. 892 IX. 892 X. 893 XI. 893 893 References 893 SUMMARY: Elicitins are structurally conserved extracellular proteins in Phytophthora and Pythium oomycete pathogen species. They were first described in the late 1980s as abundant proteins in Phytophthora culture filtrates that have the capacity to elicit hypersensitive (HR) cell death and disease resistance in tobacco. Later, they became well-established as having features of microbe-associated molecular patterns (MAMPs) and to elicit defences in a variety of plant species. Research on elicitins culminated in the recent cloning of the elicitin response (ELR) cell surface receptor-like protein, from the wild potato Solanum microdontum, which mediates response to a broad range of elicitins. In this review, we provide an overview on elicitins and the plant responses they elicit. We summarize the state of the art by describing what we consider to be the nine most important features of elicitin biology.
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Lida
authors: L
authors: Derevnina
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Yasin F
authors: YF
authors: Dagdas
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Juan Carlos
authors: JC
authors: De la Concepcion
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Aleksandra
authors: A
authors: Bialas
authors: Department of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Carl-von-Linné weg 10, 50829, Köln, Germany.
authors: Ronny
authors: R
authors: Kellner
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Benjamin
authors: B
authors: Petre
authors: Wageningen UR Plant Breeding, Wageningen University and Research Centre, Droevendaalsesteeg 1, Wageningen, 6708 PB, the Netherlands.
authors: Emmanouil
authors: E
authors: Domazakis
authors: Key Laboratory of Horticultural Plant Biology, College of Life Science and Technology, Ministry of Education National Center for Vegetable Improvement (Central China), Potato Engineering and Technology Research Center of Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.
authors: Juan
authors: J
authors: Du
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Chih-Hang
authors: CH
authors: Wu
authors: Wageningen UR Plant Breeding, Wageningen University and Research Centre, Droevendaalsesteeg 1, Wageningen, 6708 PB, the Netherlands.
authors: Xiao
authors: X
authors: Lin
authors: Wageningen UR Plant Breeding, Wageningen University and Research Centre, Droevendaalsesteeg 1, Wageningen, 6708 PB, the Netherlands.
authors: Carolina
authors: C
authors: Aguilera-Galvez
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Neftaly
authors: N
authors: Cruz-Mireles
authors: Wageningen UR Plant Breeding, Wageningen University and Research Centre, Droevendaalsesteeg 1, Wageningen, 6708 PB, the Netherlands.
authors: Vivianne G A A
authors: VG
authors: Vleeshouwers
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Sophien
authors: http://orcid.org/0000-0002-0290-0315
authors: S
authors: Kamoun
mesh_terms: D000595:Amino Acid Sequence; D060467:Disease Resistance; D009868:Oomycetes / Q000378:metabolism*; D010935:Plant Diseases / Q000382:microbiology; D010944:Plants / Q000276:immunology / Q000382:microbiology; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D011506:Proteins
keywords: INF1; cell death; elicitin response (ELR); elicitor; hypersensitive response (HR); microbe-associated molecular patterns (MAMPs); oomycetes