title: Chaperones in maturation of molybdoenzymes: Why specific is better than general?
abstract: Molybdoenzymes play essential functions in living organisms and, as a result, in various geochemical cycles. It is thus crucial to understand how these complex proteins become highly efficient enzymes able to perform a wide range of catalytic activities. It has been established that specific chaperones are involved during their maturation process. Here, we raise the question of the involvement of general chaperones acting in concert with dedicated chaperones or not.
authors: a Aix Marseille Univ, CNRS, BIP , Marseille , France.
authors: Olivier N
authors: ON
authors: Lemaire
authors: a Aix Marseille Univ, CNRS, BIP , Marseille , France.
authors: Sophie
authors: S
authors: Bouillet
authors: a Aix Marseille Univ, CNRS, BIP , Marseille , France.
authors: Vincent
authors: V
authors: Méjean
authors: a Aix Marseille Univ, CNRS, BIP , Marseille , France.
authors: Chantal
authors: C
authors: Iobbi-Nivol
authors: a Aix Marseille Univ, CNRS, BIP , Marseille , France.
authors: Olivier
authors: O
authors: Genest
mesh_terms: D001051:Apoenzymes / Q000737:chemistry / Q000378:metabolism; D003067:Coenzymes / Q000737:chemistry* / Q000378:metabolism*; D008667:Metalloproteins / Q000737:chemistry* / Q000378:metabolism*; D008954:Models, Biological; D018832:Molecular Chaperones / Q000737:chemistry* / Q000378:metabolism*; D000090006:Molybdenum Cofactors; D011621:Pteridines / Q000737:chemistry* / Q000378:metabolism*; D011622:Pterins / Q000737:chemistry / Q000378:metabolism
chemical_list: D001051:Apoenzymes; D003067:Coenzymes; D008667:Metalloproteins; D018832:Molecular Chaperones; D000090006:Molybdenum Cofactors; D011621:Pteridines; D011622:Pterins; C490076:pyranopterin; C022261:molybdopterin
keywords: general chaperone; maturation; molybdenum cofactor; molybdoenzymes; pyranopterin monophosphate; specific chaperone