title: Pulse Wave Variation during the Menstrual Cycle in Women with Menstrual Pain.
abstract: Objective. This study is performed to obtain objective diagnostic indicators associated with menstrual pain using pulse wave analysis. Methods. Using a pulse diagnostic device, we measured the pulse waves of 541 women aged between 19 and 30 years, placed in either an experimental group with menstrual pain (n = 329) or a control group with little or no menstrual pain (n = 212). Measurements were taken during both the menstrual and nonmenstrual periods, and comparative analysis was performed. Results. During the nonmenstrual period, the experimental group showed a significantly higher value in the left radial artery for the radial augmentation index (RAI) (p = 0.050) but significantly lower values for pulse wave energy (p = 0.021) and time to first peak from baseline (T1) (p = 0.035) in the right radial artery. During the menstrual period, the experimental group showed significantly lower values in the left radial artery for cardiac diastole and pulse wave area during diastole and significantly higher values for pulse wave area during systole, ratio of systolic phase to the full heartbeat, and systolic-diastolic ratio. Conclusion. We obtained indicators of menstrual pain in women during the menstrual period, including prolonged systolic and shortened diastolic phases, increases in pulse wave energy and area of representative pulse wave, and increased blood vessel resistance.
authors: Department of Sasang Constitutional Medicine, College of Korean Medicine, Dong-Eui University, Yangjeong-ro 62, Busanjin-gu, Busan 47227, Republic of Korea.
authors: Soo Hyung
authors: SH
authors: Jeon
authors: Department of Data Information Science, Dong-Eui University, Eomgwang-ro 176, Busanjin-gu, Busan 47340, Republic of Korea.
authors: Kyu Kon
authors: KK
authors: Kim
authors: Department of OB & GY, College of Korean Medicine, Dong-Eui University, Yangjeong-ro 62, Busanjin-gu, Busan 47227, Republic of Korea.
authors: In Seon
authors: IS
authors: Lee
authors: Department of Physiology, College of Korean Medicine, Dong-Eui University, Yangjeong-ro 62, Busanjin-gu, Busan 47227, Republic of Korea.
authors: Yong Tae
authors: YT
authors: Lee
authors: Department of Diagnostics, College of Korean Medicine, Dong-Eui University, Yangjeong-ro 62, Busanjin-gu, Busan 47227, Republic of Korea.
authors: Gyeong Cheol
authors: GC
authors: Kim
authors: Department of Pathology, College of Korean Medicine, Dong-Eui University, Yangjeong-ro 62, Busanjin-gu, Busan 47227, Republic of Korea.
authors: Gyoo Yong
authors: GY
authors: Chi
authors: Department of OB & GY, College of Korean Medicine, Dong-Eui University, Yangjeong-ro 62, Busanjin-gu, Busan 47227, Republic of Korea.
authors: Hye Sook
authors: HS
authors: Cho
authors: Daeyomedi Co., Ltd., 601 Gyeonggi Technopark, Haean-ro 705, Sangnok-gu, Ansan-si, Gyeonggi-do 15588, Republic of Korea.
authors: Hee Jung
authors: HJ
authors: Kang
authors: Department of Sasang Constitutional Medicine, College of Korean Medicine, Dong-Eui University, Yangjeong-ro 62, Busanjin-gu, Busan 47227, Republic of Korea.
authors: Jong Won
authors: 0000-0001-6572-3734
authors: JW
authors: Kim
mesh_terms: D000328:Adult; D004412:Dysmenorrhea / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D063177:Pulse Wave Analysis; D014655:Vascular Resistance