title: Data on IL-6 c.-174 G>C genotype and allele frequencies in patients with coronary heart disease in dependence of cardiovascular outcome.
abstract: In this data article we present data on the distribution of alleles and genotypes of the interleukin (IL)-6 c.-174 G>C polymorphism (rs 1800795) in patients with coronary heart disease (CHD) in dependence of the incidence of new cardiovascular events (combined endpoint: myocardial infarction, stroke/TIA, cardiac death, death according to stroke) within three years follow-up. Moreover, we investigated putative associations between individual expression of IL-6 genotypes and IL-6 serum level. This investigation is a subanalysis of the article entitled "The Interleukin 6 c.-174 CC genotype is a predictor for new cardiovascular events in patients with coronary heart disease within three years follow-up" (ClinicalTrials.gov identifier: NCT01045070) (Reichert et al., 2016) [1].
authors: Department of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
authors: Stefan
authors: S
authors: Reichert
authors: Department of Cardiology, Paracelsus-Harz-Clinic Bad Suderode, Quedlinburg, Germany; Department of Internal Medicine III, Martin-Luther-University Halle-Wittenberg, Germany.
authors: Axel
authors: A
authors: Schlitt
authors: Department of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
authors: Ann-Christin
authors: AC
authors: Benten
authors: Department of Cardiothoracic Surgery, Heart Centre of the University Clinics Halle (Saale), Martin-Luther-University Halle-Wittenberg, Germany.
authors: Britt
authors: B
authors: Hofmann
authors: Department of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
authors: Hans-Günter
authors: HG
authors: Schaller
authors: Department of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Germany.
authors: Susanne
authors: S
authors: Schulz
keywords: Coronary heart disease; IL-6 polymorphism; IL-6 serum level; New cardiovascular events