title: Correlation between mycosis fungoides and pregnancy.
abstract: OBJECTIVE
  To evaluate the effect of pregnancy on the natural course of Mycosis fungoides (MF) and compare the obtained results with previous reports.
  
  
  METHODS
  The medical records of 140 patients with cutaneous T-cell lymphoma (CTCL) treated at the University Hospital of Isfahan (the academic referral center for CTCL) Isfahan, Iran. Between 2000 and 2013 were retrospectively reviewed to retrieve all cases of pregnancy during the course of MF disease.
  
  
  RESULTS
  A total of 8 pregnancies were recorded. The median age of patients at the time of diagnosis was 26.7 (range 21-30 years) and pregnancy 29.4 (range 27-31 years). Most of patients had early-stage MF (Ia and Ib). All patients experienced aggravation of disease during pregnancy or immediately postpartum. Mycosis fungoides did not cause any complications during pregnancy.
  
  
  CONCLUSIONS
  Pregnancy appears to have a negative impact on the course of MF, probably due to immune system deteriorations during the pregnancy. Further studies are needed to clarify the interplay between pregnancy and MF.
authors: Department of Dermatology, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical sciences, Isfahan, Iran. E-mail. fatemi_farahnaz@yahoo.com.
authors: Farahnaz
authors: F
authors: Fatemi Naeini
authors: Bahareh
authors: B
authors: Abtahi-Naeini
authors: Jamshid
authors: J
authors: Najafian
authors: Ali
authors: A
authors: Saffaei
authors: Mohsen
authors: M
authors: Pourazizi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009182:Mycosis Fungoides / Q000503:physiopathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000503:physiopathology; D012189:Retrospective Studies