title: miRNA-Dependent Activation of mRNA Translation.
abstract: MicroRNAs (miRNAs) are small and important RNA molecules. They can regulate gene expression at different levels. Although their biogenesis has been well documented, elucidation of miRNA-dependent activation of mRNA translation has just begun. Here, we highlighted different patterns of miRNA-dependent activation of mRNA translation: miRNA can activate mRNA translation through binding different target sites; in different sub-cellular locations; under different cellular circumstances. MiRNA-dependent activation of mRNA translation suggests unexpected functions of miRNA, that could provide new clues in functional studies of other ncRNAs.
authors: Wen-Juan
authors: WJ
authors: Ni
authors: Department of Neurology, The First Affiliated Hospital of Xinxiang Medical University, Henan 453100, People&#39;s Republic of China. m13781936681@163.com.
authors: Xiao-Min
authors: XM
authors: Leng
mesh_terms: D001665:Binding Sites / Q000235:genetics; D005786:Gene Expression Regulation / Q000235:genetics*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D014176:Protein Biosynthesis / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*
chemical_list: D035683:MicroRNAs; D012333:RNA, Messenger