title: Safety and Effectiveness of the Denali Inferior Vena Cava Filter: Intermediate Follow-Up Results.
abstract: OBJECTIVE
  The purpose of the study is to evaluate the clinical safety and effectiveness of the Denali (Bard, Tempe, Arizona) retrievable inferior vena cava (IVC) filter.
  
  
  METHODS
  In this retrospective study, authors reviewed the data of Denali IVC filters placed at their institution between 2013 and 2015. The clinical presentation, indications, and procedure-related complications during placement and retrieval were evaluated. The frequency of post filter pulmonary embolism (PE) and filter-related complications was assessed.
  
  
  RESULTS
  Denali filters were placed in 87 patients (47 males; mean age: 56 years). Twenty patients presented with PE, 45 with deep vein thrombosis (DVT), and 21 with both PE and DVT, 1 filter was placed prophylactically before surgery. Indications for filter placement included contraindications to anticoagulation (AC; n = 80), failure of AC (n = 4), and complications of AC (n = 3). No patients had PE on follow-up imaging after filter placement. Retrieval was attempted in 31 patients after a mean period of 125 days (range: 34-324 days). The filter was successfully removed in 31 (100%) patients. Follow-up imaging, available in 71 (82%) patients (range: 2-538 days), demonstrated penetration of 15 legs in 5 patients, caval thrombus in 3, 1 resulting in caval occlusion, <15° filter tilt in 5, and no leg fractures or crossed legs.
  
  
  CONCLUSIONS
  The Denali filter is safe during deployment and readily retrievable. The overall safety following deployment is similar to those reported in the literature, and the incidence of filter fractures and migration appears to be less than the previous generation of Bard devices.
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA sr3321@cumc.columbia.edu.
authors: Stephen P
authors: SP
authors: Reis
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
authors: Jerry
authors: J
authors: Kovoor
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
authors: Patrick D
authors: PD
authors: Sutphin
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
authors: Seth
authors: S
authors: Toomay
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
authors: Clayton
authors: C
authors: Trimmer
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
authors: Anil
authors: A
authors: Pillai
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
authors: Mark
authors: M
authors: Reddick
authors: Division of Interventional Radiology, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
authors: Sanjeeva P
authors: SP
authors: Kalva
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000072226:Computed Tomography Angiography; D020878:Device Removal; D005260:Female; D005548:Foreign-Body Migration / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010690:Phlebography / Q000379:methods; D011474:Prosthesis Design; D011475:Prosthesis Failure; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D012189:Retrospective Studies; D012307:Risk Factors; D013781:Texas; D013997:Time Factors; D016896:Treatment Outcome; D016306:Vena Cava Filters; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging; D020246:Venous Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D055815:Young Adult
keywords: DVT; PE; filter complications; inferior vena cava filter