title: Histopathological findings in wild Nutrias (Myocastor coypus) with Capillaria hepatica infection.
abstract: Capillaria hepatica is a zoonotic nematode that uses rodents and other mammals as hosts, especially rats and mice, and causes hepatic granuloma and eventually fibrosis/cirrhosis. However, C. hepatica infection in nutria, a large semiaquatic rodent, has rarely been reported, and histopathologic features of the infection have not been described in detail. We conducted necropsy on 36 wild nutrias. Some animals were found to have milky spots, parasitic eggs and worms within hepatic microgranuloma involving central calcification with cell debris, macrophages, eosinophils and multinucleated giant cells (MGCs). Interestingly, the eggs were closely surrounded by MGCs and appeared to be destroyed without inducing further chronic changes. Based on microscopical examination, C. hepatica infection was diagnosed, and we describe its histopathological characteristics in wild nutrias.
authors: Institute of Animal Medicine, Gyeongsang National University, Jinju, Republic of Korea.
authors: Il-Hwa
authors: IH
authors: Hong
authors: Sun-Young
authors: SY
authors: Kang
authors: Jong-Hyun
authors: JH
authors: Kim
authors: Seong-Hoon
authors: SH
authors: Seok
authors: Seong-Kyu
authors: SK
authors: Lee
authors: Seong-Jin
authors: SJ
authors: Hong
authors: Seung-Yong
authors: SY
authors: Lee
authors: Se-Jin
authors: SJ
authors: Park
authors: Joo-Yeon
authors: JY
authors: Kong
authors: Seong-Chan
authors: SC
authors: Yeon
mesh_terms: D000818:Animals; D002195:Capillaria / Q000302:isolation & purification*; D017189:Enoplida Infections / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D015726:Giant Cells / Q000473:pathology; D006099:Granuloma / Q000469:parasitology / Q000473:pathology / Q000662:veterinary; D008099:Liver / Q000469:parasitology / Q000473:pathology*; D008297:Male; D056910:Republic of Korea / Q000453:epidemiology; D012376:Rodent Diseases / Q000469:parasitology / Q000473:pathology*; D012377:Rodentia