title: The analysis of correlative factors affecting long-term outcomes in patients with Solid Cerebellar Hemangioblastomas.
abstract: OBJECTIVE
  Analyze the factors affecting postoperative outcomes in patients with solid cerebellar hemangioblastomas.
  
  
  METHODS
  We retrospectively analyzed the clinical data of 22 patients with sporadic solid cerebellar hemangioblastomas. Data regarding the clinical materials and imaging features, diameter of the lesion, operative approaches and postoperative complications were analyzed in all patients. The factors that may affect the recovery of postoperative patients were analyzed by univariate analysis and logistic regression multivariate analysis.
  
  
  RESULTS
  All 22 patients were diagnosed with sporadic solid cerebellar hemangioblastomas; total resection was achieved in 21 of 22 patients (95.5%). Six patients with combined obstructive hydrocephalus received a ventricle-peritoneal shunt preoperatively. The mean duration of the follow-up period was 25.5 months (range, 6-72 months). Tumor recurrence occurred in two patients with poor prognosis at 12 months and 56 months after surgery. According to outcome, patients were divided into the poor group (4 of 22 patients, 18.2%), in which neurological symptoms persisted postoperatively, or were worse than preoperatively, and the good group (18 of 22 patients, 81.8%) with no neurological signs or improved symptoms postoperatively. After univariate analysis, the factor affecting the final outcome was postoperative hemorrhage (P=0.003). Moreover, multiple logistic regression analysis via R software indicated that postoperative hemorrhage (p=0.008) was correlated with outcomes.
  
  
  CONCLUSIONS
  Postoperative hemorrhage is a factor correlated with final outcomes of patients with sporadic solid cerebellar hemangioblastomas.
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Liang
authors: L
authors: Niu
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Yinian
authors: Y
authors: Zhang
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Qiao
authors: Q
authors: Li
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Junqiang
authors: J
authors: Dai
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Hang
authors: H
authors: Yin
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Lei
authors: L
authors: Duan
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Hu
authors: H
authors: Yang
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Wentao
authors: W
authors: Liang
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Zhenwei
authors: Z
authors: Qin
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China.
authors: Jianping
authors: J
authors: Zhang
authors: Department of Neurosurgery, Lanzhou University Second Hospital, China; Institute of Neurology, Lanzhou University Second Hospital, China. Electronic address: panyawenniuliang@163.com.
authors: Yawen
authors: Y
authors: Pan
mesh_terms: D000328:Adult; D000368:Aged; D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D018325:Hemangioblastoma / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011183:Postoperative Complications; D012189:Retrospective Studies; D055815:Young Adult
keywords: Cerebellar hemangioblastomas; Postoperative outcomes; Solid tumor; Surgery