title: RETRACTED: Potential role of andrographolide in the proliferation of osteoblasts mediated by the ERK signaling pathway.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
  
  This article has been retracted at the request of the Editor-in-Chief.
  
  The authors contacted the journal to request a retraction: "We found some errors in reviewing the original data, the current results could not fully support the conclusions". Concern was also raised about the reliability of the Western blot results in Figure 8A+E, which appear to have a similar phenotype as contained within other publications, as detailed here: https://pubpeer.com/publications/CC36842602D94EB300623ED982FBFA; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Concerns were also raised about suspected image duplications within Figure 1C. The journal requested the corresponding author comment on these concerns and provide the raw data. The author did not fulfil this request and the Editor-in-Chief decided to retract the article.
authors: Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang 550002, PR China; Guangxi Medical University, Nanning 530021, PR China.
authors: Bo
authors: B
authors: Li
authors: Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang 550002, PR China.
authors: Ru-Yin
authors: RY
authors: Hu
authors: Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang 550002, PR China.
authors: Li
authors: L
authors: Sun
authors: Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang 550002, PR China.
authors: Rui
authors: R
authors: Luo
authors: Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang 550002, PR China.
authors: Kai-Hang
authors: KH
authors: Lu
authors: Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang 550002, PR China. Electronic address: myronlee2014@126.com.
authors: Xiao-Bin
authors: XB
authors: Tian
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D049109:Cell Proliferation / Q000187:drug effects* / Q000502:physiology; D002478:Cells, Cultured; D004224:Diterpenes / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D020935:MAP Kinase Signaling System / Q000187:drug effects* / Q000502:physiology; D010006:Osteoblasts / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004224:Diterpenes; C030419:andrographolide
keywords: Andrographolide; Extracellular signal regulated kinase; Mitogen-activated protein kinases pathway; Osteoblasts; Proliferation; U0126; c-Jun NH2-terminal kinase; p38