title: Three New Isoprenylated Flavonoids from the Root Bark of Morus alba.
abstract: Phytochemical investigation of the root bark of Morus alba has led to the isolation and identification of three new isoprenylated flavonoids, namely sanggenon U (1), sanggenon V (2), and sanggenon W (3), along with four known isoprenylated flavonoids: euchrenone a₇ (4), sanggenon J (5), kuwanon E (6), and kuwanon S (7). All compounds were isolated by repeated silica gel (SiO₂), octadecyl SiO₂ (ODS), and Sephadex LH-20 open column chromatography. The structure of the compounds were determined based on spectroscopic analyses, including nuclear magnetic resonance (NMR), mass spectrometry (MS), circular dichroism (CD), and infrared (IR). In addition, compounds 1-4 were isolated for the first time from the root bark of M. alba in this study.
authors: Graduate School of Biotechnology and Oriental Medicine Biotechnology, Kyung Hee University, Yongin 17104, Korea. jaewoo4848@naver.com.
authors: Jae-Woo
authors: JW
authors: Jung
authors: Graduate School of Biotechnology and Oriental Medicine Biotechnology, Kyung Hee University, Yongin 17104, Korea. pjh3411@kbsi.re.kr.
authors: Ji-Hae
authors: JH
authors: Park
authors: Graduate School of Biotechnology and Oriental Medicine Biotechnology, Kyung Hee University, Yongin 17104, Korea. lyg629@nate.com.
authors: Yeong-Geun
authors: YG
authors: Lee
authors: Natural Medicine Research Center, KRIBB, Chengju 28116, Korea. khseo@kribb.re.kr.
authors: Kyeong-Hwa
authors: KH
authors: Seo
authors: Graduate School of Biotechnology and Oriental Medicine Biotechnology, Kyung Hee University, Yongin 17104, Korea. JK3172@nate.com.
authors: Eun-Ji
authors: EJ
authors: Oh
authors: Department of Herbal Crop Research, National Institute of Horticultural and Herbal Science, RDA, Eumseong 27709, Korea. dylee0809@korea.kr.
authors: Dae-Young
authors: DY
authors: Lee
authors: Division of Metabolism and Functionality Research, Korea Food Research Institute, Sungnam 463-746, Korea. neodw4015@kfri.re.kr.
authors: Dong-Wook
authors: DW
authors: Lim
authors: Division of Metabolism and Functionality Research, Korea Food Research Institute, Sungnam 463-746, Korea. imissu@kfri.re.kr.
authors: Daeseok
authors: D
authors: Han
authors: Graduate School of Biotechnology and Oriental Medicine Biotechnology, Kyung Hee University, Yongin 17104, Korea. nibaek@khu.ac.kr.
authors: Nam-In
authors: NI
authors: Baek
mesh_terms: D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification*; D015394:Molecular Structure; D031625:Morus / Q000737:chemistry*; D024301:Plant Bark / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*
chemical_list: D005419:Flavonoids
keywords: Morus alba; isoprenylated flavonoids; root bark; sanggenon U; sanggenon V; sanggenon W