title: The plastid metalloprotease FtsH6 and small heat shock protein HSP21 jointly regulate thermomemory in Arabidopsis.
abstract: Acquired tolerance to heat stress is an increased resistance to elevated temperature following a prior exposure to heat. The maintenance of acquired thermotolerance in the absence of intervening stress is called 'thermomemory' but the mechanistic basis for this memory is not well defined. Here we show that Arabidopsis HSP21, a plastidial small heat shock protein that rapidly accumulates after heat stress and remains abundant during the thermomemory phase, is a crucial component of thermomemory. Sustained memory requires that HSP21 levels remain high. Through pharmacological interrogation and transcriptome profiling, we show that the plastid-localized metalloprotease FtsH6 regulates HSP21 abundance. Lack of a functional FtsH6 protein promotes HSP21 accumulation during the later stages of thermomemory and increases thermomemory capacity. Our results thus reveal the presence of a plastidial FtsH6-HSP21 control module for thermomemory in plants.
authors: University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße 24-25, Haus 20, 14476 Potsdam-Golm, Germany.|Max Planck Institute of Molecular Plant Physiology, Cooperative Research Group, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany.
authors: Mastoureh
authors: M
authors: Sedaghatmehr
authors: University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße 24-25, Haus 20, 14476 Potsdam-Golm, Germany.|Max Planck Institute of Molecular Plant Physiology, Cooperative Research Group, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany.
authors: Bernd
authors: B
authors: Mueller-Roeber
authors: University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße 24-25, Haus 20, 14476 Potsdam-Golm, Germany.|Max Planck Institute of Molecular Plant Physiology, Cooperative Research Group, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany.
authors: Salma
authors: S
authors: Balazadeh
mesh_terms: D017360:Arabidopsis / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000502:physiology*; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D006360:Heat-Shock Proteins / Q000502:physiology*; D018869:Heat-Shock Response / Q000502:physiology*; D045726:Metalloproteases / Q000502:physiology*; D030821:Plants, Genetically Modified / Q000502:physiology; D018087:Plastids / Q000502:physiology; D000071436:Thermotolerance / Q000502:physiology*
chemical_list: D029681:Arabidopsis Proteins; C400143:HSP21 protein, Arabidopsis; D006360:Heat-Shock Proteins; C505163:FtsH6 protein, Arabidopsis; D045726:Metalloproteases