title: Prognostic Significance of the Preoperative Lymphocyte to Monocyte Ratio in Patients With Stage I Non-Small Cell Lung Cancer Undergoing Complete Resection.
abstract: In this study, we investigated the correlation between lymphocyte to monocyte ratio (LMR) and clinical outcomes in stage I non-small cell lung cancer (NSCLC) patients. A total of 439 stage I NSCLC patients were enrolled in this study. Multivariate analyses identified LMR as an independent prognostic factor for recurrence-free survival and overall survival (hazard ratio (HR: 0.469, 95% Confidence Interval (CI): 0.325-0.677, and p < 0.001, and HR: 0.478, 95% CI: 0.332-0.688, and p < 0.001; respectively). Compared with the high LMR group, the proportion of patients who developed distant metastasis was significantly higher in the low LMR group.
authors: a Department of Cardiothoracic Surgery , Tianjin Hospital , Tianjin , China.
authors: Honggang
authors: H
authors: Xia
authors: a Department of Cardiothoracic Surgery , Tianjin Hospital , Tianjin , China.
authors: Zhongyi
authors: Z
authors: Sun
authors: a Department of Cardiothoracic Surgery , Tianjin Hospital , Tianjin , China.
authors: Limin
authors: L
authors: Deng
authors: a Department of Cardiothoracic Surgery , Tianjin Hospital , Tianjin , China.
authors: Deqing
authors: D
authors: Zhu
authors: a Department of Cardiothoracic Surgery , Tianjin Hospital , Tianjin , China.
authors: Dongbin
authors: D
authors: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000097:blood* / Q000175:diagnosis / Q000401:mortality* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D007958:Leukocyte Count; D008175:Lung Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000401:mortality* / Q000601:surgery; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D009000:Monocytes; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D057234:Preoperative Period; D011379:Prognosis; D012372:ROC Curve; D012189:Retrospective Studies
keywords: Lymphocyte to monocyte ratio; non-small cell lung cancer; prognosis