title: Adult ADHD Medications and Their Cardiovascular Implications.
abstract: Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder exhibited by difficulty maintaining attention, as well as hyperactivity and impulsive behavior. Central nervous system (CNS) stimulants are the first line of treatment for ADHD. With the increase in number of adults on CNS stimulants, the question that arises is how well do we understand the long-term cardiovascular effects of these drugs. There has been increasing concern that adults with ADHD are at greater risk for developing adverse cardiovascular events such as sudden death, myocardial infarction, and stroke as compared to pediatric population. Cardiovascular response attributed to ADHD medication has mainly been observed in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events like acute myocardial infarction (AMI), arrhythmia, and cardiomyopathy and its long-term sequelae. We present a unique case of AMI in an adult taking Adderall (mixed amphetamine salts) and briefly discuss the literature relevant to the cardiovascular safety of CNS stimulants for adult ADHD.
authors: Division of Cardiology, Saint Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USA.
authors: A
authors: 0000-0001-9404-1679
authors: A
authors: Sinha
authors: Division of Pulmonary Medicine, Department of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.
authors: O
authors: O
authors: Lewis
authors: Department of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.
authors: R
authors: 0000-0001-7244-4688
authors: R
authors: Kumar
authors: Division of Hematology & Oncology, Department of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.
authors: S L H
authors: 0000-0001-8937-0662
authors: SL
authors: Yeruva
authors: Division of Cardiology, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USA.
authors: B H
authors: 0000-0003-3456-6937
authors: BH
authors: Curry