title: Nanoscale Polymer Metal-Organic Framework Hybrids for Effective Photothermal Therapy of Colon Cancers.
abstract: A UiO-66 core with various sizes acts as heterogeneous nucleation center and enables aniline polymerization under ambient conditions. The as-synthesized UiO-66@PAN possesses uniform size and excellent dispersibility in aqueous solution. UiO-66@PAN can be internalized by cancer cells via endocytosis, and indicates significant photothermal therapeutic effect in vitro, and can effectively inhibit the growth of colon cancers in vivo.
authors: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors: Weiqi
authors: W
authors: Wang
authors: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.
authors: Lei
authors: L
authors: Wang
authors: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.|College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 060004, P. R. China.
authors: Yang
authors: Y
authors: Li
authors: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.
authors: Shi
authors: S
authors: Liu
authors: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.
authors: Zhigang
authors: Z
authors: Xie
authors: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin, 130022, P. R. China.
authors: Xiabin
authors: X
authors: Jing
mesh_terms: D003110:Colonic Neoplasms / Q000473:pathology / Q000628:therapy*; D004705:Endocytosis; D045325:HCT116 Cells; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D000073396:Metal-Organic Frameworks / Q000737:chemistry*; D010789:Phototherapy / Q000379:methods*; D011108:Polymers / Q000737:chemistry*
chemical_list: D000073396:Metal-Organic Frameworks; D011108:Polymers
keywords: metal-organic frameworks; photothermal therapy; polyanilines