title: Comparison of Tpe Changing on ECG, in Pre and Post Dialysis and Post Transplantation.
abstract: BACKGROUND
  High incidence of premature ventricular contractions (PVCS) and arrhythmia during and soon after dialysis have been demonstrated by Holter monitoring.
  
  
  OBJECTIVE
  In this study, the effects of dialysis and renal transplantation on Tpe, Tpec (corrected Tpe), QTc (corrected QT), QTd (QT dispersion), and Tpe/QT parameters as known factors in arrhythmogenicity, and also the correlation between electrolyte and arterial blood gas changing within these parameters will be assessed.
  
  
  METHODS
  In a retrospective study, 42 renal transplant recipients were selected. Under the supervision of an electrophysiologist, information related to Tpe, Tpec, Tpe/QT, QTd, and QTc parameters before dialysis (pre-HD), after dialysis (post-HD), and two weeks after transplantation (RTX) were analyzed. Electrolyte and arterial blood gas information were also recorded. Bonferroni adjustment, repeated measures ANOVA, generalized linear models, and generalized estimating equations were used for analysis.
  
  
  RESULTS
  Two weeks after transplantation, the mean Tpe decreased to 0.052 ± 0.002, which was significant compared to pre-HD (P < 0.001) and Post-HD (P = 0.019). The mean Tpec was 0.059 ± 0.002, which, just in comparison to pre-HD, was significant (P = 0.005). In addition, the mean Tpe/QT decreased to 0.143 ± 0.005, which was significant compared to pre-HD (P = 0.018). The mean QTd was 0.066 ± 0.004, which wasn't significant compared to before or after dialysis. The mean QTc decreased to 0.386 ± 0.004, which was significant compared to post-HD (P = 0.0003).
  
  
  CONCLUSIONS
  Taking the role of Tpe and Tpe/QT in arrhythmia into account and amending it by a successful transplantation can be considered as a factor that decreases arrhythmia after renal transplantation compared to ESRD patients.
authors: Urology Research Center, Guilan University of Medical Sciences, Rasht, IR Iran.
authors: Ali
authors: A
authors: Monfared
authors: Cardiology Research Center, Guilan University of Medical Sciences, Rasht, IR Iran.
authors: Mohammad
authors: M
authors: Assadian Rad
authors: Urology Research Center, Guilan University of Medical Sciences, Rasht, IR Iran.
authors: Mohammadreza
authors: M
authors: Feizkhah
authors: Urology Research Center, Guilan University of Medical Sciences, Rasht, IR Iran.
authors: Ehsan
authors: E
authors: Kazemnezhad
authors: Urology Research Center, Guilan University of Medical Sciences, Rasht, IR Iran.
authors: Samaneh
authors: S
authors: Esmaeili
authors: Urology Research Center, Guilan University of Medical Sciences, Rasht, IR Iran.
authors: Nadia
authors: N
authors: Rastjou Herfeh
authors: Urology Research Center, Guilan University of Medical Sciences, Rasht, IR Iran.
authors: Razieh
authors: R
authors: Hedayatsafa
keywords: ESRD; Electrolyte; Failure; Hemodialysis; Tpe; Transplant