title: Bacterial peptide transporters: Messengers of nutrition to virulence.
abstract: Bacteria possess numerous peptide transporters for importing peptides as nutrients. However, these peptide transporters are now consistently reported to play a role in the virulence of various bacterial pathogens. Their ability to transport peptides has implications in antibacterial therapy as well. Therefore, it would be instrumental to have complete knowledge about the role of peptide transporters in mediating this cross connection between metabolism and pathogenesis. Studies on various peptide transporters in bacterial pathogens have improved our understanding of this field. In this review, we have given an overview of the functioning of bacterial peptide transporters and their contribution in virulence of major bacterial pathogens.
authors: a Department of Microbiology and Cell Biology , Indian Institute of Science , Bangalore , India.
authors: Preeti
authors: P
authors: Garai
authors: a Department of Microbiology and Cell Biology , Indian Institute of Science , Bangalore , India.
authors: Kasturi
authors: K
authors: Chandra
authors: a Department of Microbiology and Cell Biology , Indian Institute of Science , Bangalore , India.
authors: Dipshikha
authors: D
authors: Chakravortty
mesh_terms: D001419:Bacteria / Q000254:growth & development* / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism*; D004734:Energy Metabolism; D026901:Membrane Transport Proteins / Q000378:metabolism*; D014774:Virulence
chemical_list: D001426:Bacterial Proteins; D026901:Membrane Transport Proteins; C043912:peptide permease
keywords: ABC transporters; PTR transporters; antimicrobial therapy; bacterial pathogens; metabolism; peptide transporters; virulence