title: A rare case report of primary bone lymphoma and a brief review of the literature.
abstract: Primary bone lymphoma is a rare and peculiar extranodal presentation of non-Hodgkin's lymphoma, which threatens human health. It can be defined as a lymphoma that occurs in the bone, consisting of a single bone lesion with or without regional lymphadenopathies, and its underlying causes are largely unknown. In this case report, we describe a male who presented with left-sided distal forearm pain, swelling of 2 months duration, and progressive limited wrist motion for about 1 month. The patient had no significant medical history except diabetes. Magnetic Resonance Imaging demonstrated a sheet-like bone destruction area in the left-sided radius, localized discontinuous bone cortex, and adjacent soft tissue masses. Finally, a bone biopsy examined by histopathological and immunochemical methods confirmed a diagnosis of primary bone diffuse large B-cell lymphoma. Due to the rarity of this disease, the level of evidence supporting some diagnostic and therapeutic decisions remains low, and therefore, the details of the rare case may facilitate treatment of similar diseases and provide insight about this obscure lymphoproliferative malignancy. Also, related recent literature reports of primary bone lymphoma are reviewed.
authors: School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences; Department of Oncology, Shandong Cancer Hospital affiliated to Shandong University.
authors: Jia
authors: J
authors: Wang
authors: School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences; Department of Intervention, Qihe People's Hospital.
authors: Shouren
authors: S
authors: Fan
authors: Department of Oncology, Shandong Cancer Hospital affiliated to Shandong University.
authors: Jie
authors: J
authors: Liu
authors: Elementary Laboratory, Shandong Cancer Hospital affiliated to Shandong University, Jinan, People's Republic of China.
authors: Bao
authors: B
authors: Song
keywords: DLBCL; consolidation radiotherapy; diffuse large B-cell lymphoma; primary DLBCL bone lymphoma; radius; rituximab