title: [Composition and biological activity of triterpenes and steroids from Inonotus obliquus (chaga)].
abstract: Data on the chemical composition of triterpenic and steroid compounds, isolated from the chaga mushroom grown in natural environment or in a synthetic culture have been summarized. Special attention has been paid to the biological activity of chaga mushroom extracts and these particular compounds against various cancer cell lines in vitro and in vivo. This analysis has demonstrated some common features in inhibition of growth of various cell lines by chaga mushroom components. In this context, the most active are triterpene compounds containing OH group at C-22 and a side chain unsaturated bond.
authors: Kazan National Research Technological University, Kazan, Russia.
authors: S A
authors: SA
authors: Nikitina
authors: Kazan National Research Technological University, Kazan, Russia.
authors: V R
authors: VR
authors: Khabibrakhmanova
authors: Kazan National Research Technological University, Kazan, Russia.
authors: M A
authors: MA
authors: Sysoeva
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D001487:Basidiomycota / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry* / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D013256:Steroids; D014315:Triterpenes
keywords: biological activity; chaga mushroom; in vitro; in vivo; steroids; triterpenes