title: Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa.
abstract: Deficits in neuropsychological functioning have consistently been identified in patients with anorexia nervosa (AN). However, little is known on how decision making in AN patients evolves in response to treatment or whether impairments are reversible.
  
  
  
  AN patients (n = 42) completed the Iowa Gambling Task (IGT) upon admission to a 3-month day-hospital treatment programme and at a 1-year follow-up. Patient IGT performance was compared to age-matched controls (n = 46).
  
  
  
  AN patients displayed poorer performance on the IGT at admission compared to controls (p < .001). Patients with full remission (n = 31; 73.9%) at the 1-year follow-up improved IGT performance (p = 0.007), and scores were similar compared to controls (p = 0.557). AN patients with partial/no remission at follow-up (n = 11; 26.1%) did not improve IGT scores (p = 0.867).
  
  
  
  These findings uphold that enduring remission from AN can reverse decision-making impairments, and they might be most likely explained by clinical state rather than a trait vulnerability. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.|CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.
authors: Trevor
authors: T
authors: Steward
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.|CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.
authors: Gemma
authors: G
authors: Mestre-Bach
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.|CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.
authors: Zaida
authors: Z
authors: Agüera
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Departament de Psicobiologia i Metodologia de les Ciències de la Salut, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Roser
authors: R
authors: Granero
authors: Departament de Psicologia Clínica, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Virginia
authors: V
authors: Martín-Romera
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.|CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.
authors: Isabel
authors: I
authors: Sánchez
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.|CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.
authors: Nadine
authors: N
authors: Riesco
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.
authors: Iris
authors: I
authors: Tolosa-Sola
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.
authors: Jose A
authors: JA
authors: Fernández-Formoso
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Diabetes, Endocrinology and Nutrition, Hospital Clínico Universitario Virgen de Victoria, Málaga, Spain.
authors: Jose C
authors: 0000-0003-2229-8488
authors: JC
authors: Fernández-García
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Diabetes, Endocrinology and Nutrition, Hospital Clínico Universitario Virgen de Victoria, Málaga, Spain.
authors: Francisco J
authors: FJ
authors: Tinahones
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Medicine, Endocrinology Division, Santiago de Compostela University, Complejo Hospitalario Universitario, Santiago de Compostela, Spain.
authors: Felipe F
authors: FF
authors: Casanueva
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Psychological, Personality, Evaluation and Treatment of the University of Valencia, Valencia, Spain.
authors: Rosa M
authors: RM
authors: Baños
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Basic Psychology, Clinic and Psychobiology of the University Jaume I, Castelló, Spain.
authors: Cristina
authors: C
authors: Botella
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Medicine, Endocrinology Division, Santiago de Compostela University, Complejo Hospitalario Universitario, Santiago de Compostela, Spain.
authors: Ana B
authors: AB
authors: Crujeiras
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Integrated Pharmacology and Systems Neurosciences Research Group, Neuroscience Research Program Organization IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.|Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
authors: Rafael
authors: R
authors: de la Torre
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Diabetes, Endocrinology and Nutrition, Institu d'Investigació, Biomèdica de Girona (IdIBGi), Hospital Dr Josep Trueta, Girona, Spain.
authors: Jose M
authors: JM
authors: Fernández-Real
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra-IdiSNA, Pamplona, Spain.
authors: Gema
authors: G
authors: Frühbeck
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Diabetes, Endocrinology and Nutrition, Institu d'Investigació, Biomèdica de Girona (IdIBGi), Hospital Dr Josep Trueta, Girona, Spain.
authors: Francisco J
authors: FJ
authors: Ortega
authors: CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra-IdiSNA, Pamplona, Spain.
authors: Amaia
authors: A
authors: Rodríguez
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.|CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain.|Department of Clinical Sciences, School of Medicine, University of Barcelona, Spain.
authors: Susana
authors: S
authors: Jiménez-Murcia
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.|Department of Clinical Sciences, School of Medicine, University of Barcelona, Spain.|CIBER Salud Mental (CIBERSAM), Instituto Salud Carlos III, Barcelona, Spain.
authors: Jose M
authors: JM
authors: Menchón
authors: Department of Psychiatry, Bellvitge University Hospital-IDIBELL, Barcelona, Spain. ffernandez@bellvitgehospital.cat.|CIBER Fisiopatologia Obesidad y Nutrición (CIBEROBN), Instituto Salud Carlos III, Barcelona, Spain. ffernandez@bellvitgehospital.cat.|Department of Clinical Sciences, School of Medicine, University of Barcelona, Spain. ffernandez@bellvitgehospital.cat.
authors: Fernando
authors: 0000-0002-2968-9898
authors: F
authors: Fernández-Aranda
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000503:physiopathology* / Q000523:psychology*; D003657:Decision Making / Q000502:physiology; D005260:Female; D005715:Gambling / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D009483:Neuropsychological Tests; D012074:Remission Induction; D013647:Task Performance and Analysis
keywords: choice behaviour; cognitive behavioural therapy; cognitive impairments; eating and feeding disorders; longitudinal studies; neuropsychology