title: [Validation of the Montgomery-Åsberg Depression Rating Scale (MADRS) in Colombia].
abstract: OBJECTIVE
  To adapt and to validate the Montgomery-Åsberg Depression Rating Scale (MADRS) in Colombia.
  
  
  METHODS
  Observational study for scale validation. Validity criteria were used to determine the severity cut-off points of the tool. Taking into account sensitivity and specificity values, those cut points were contrasted with ICD-10 criteria for depression severity. A a factor analysis was performed. The internal consistencY was determined with the same sample of patients used for the validity criteria. Inter-rater reliability was assessed by evaluating the 22 records of the patients that consented to a video interview. Sensitivity to change was established through a second application of the scale in 28 subjects after a lapse of 14 to 28 days.
  
  
  RESULTS
  The study was performed in Bogotá, the tool was applied in 150 patients suffering from major depressive disorder. The cut-off point for moderate depression was 20 (sensitivity, 98%; specificity, 96%), and the cut-off point for severe depression was 34 (sensitivity, 98%; specificity, 92%). The tool appears as a unidimensional scale, which possesses a good internal consistency with (α=.9168). The findings of inter-rater reliability evaluation showed the scale as highly reliable (intraclass correlation coefficient=.9833). The instrument has a good sensitivity to change.
  
  
  CONCLUSIONS
  The Colombian version of the Montgomery-Åsberg Depression Rating Scale has good psychometric properties and can be used in clinical practice and in clinical research in the field of depressive disorder.
authors: Centro de Investigaciones del Sistema Nervioso, Grupo CISNE, Bogotá, Colombia. Electronic address: juan.cano@grupocisne.org.
authors: Juan Fernando
authors: JF
authors: Cano
authors: Departamento de Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors: Carlos
authors: C
authors: Gomez Restrepo
authors: Departamento de Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors: Martín
authors: M
authors: Rondón
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003105:Colombia; D003865:Major Depressive Disorder / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012680:Sensitivity and Specificity
keywords: Colombia; Depresión; Depression; Estudios de validación; Validation studies