title: Pituitary Apoplexy After Initial Leuprolide Injection.
abstract: BACKGROUND
  Pituitary apoplexy is a rare complication of the initial administration of leuprolide acetate.
  
  
  METHODS
  We present the case of a 63-year-old man who experienced headache, blurred vision, and loss of consciousness after initial leuprolide treatment for prostate carcinoma. Neuroimaging showed pituitary hemorrhage.
  
  
  CONCLUSIONS
  Clinicians should be aware of this rare but known complication of leuprolide injection so that prompt diagnosis and treatment initiation are performed in patients with leuprolide-associated pituitary apoplexy.
authors: Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, New York, USA; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA. Electronic address: Andrew.Fabiano@RoswellPark.org.
authors: Andrew J
authors: AJ
authors: Fabiano
authors: Department of Medical Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA; Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.
authors: Saby
authors: S
authors: George
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D002277:Carcinoma / Q000188:drug therapy*; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging; D017024:Chemotherapy, Adjuvant; D006801:Humans; D016729:Leuprolide / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010899:Pituitary Apoplexy / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000188:drug therapy*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D016729:Leuprolide
keywords: Leuprolide acetate; Pituitary apoplexy; Pituitary hemorrhage; Prostate cancer