title: Medications for Allergic Rhinitis.
abstract: Objectives Adherence to the allergic rhinitis clinical practice guideline is being considered as a potential focus for national performance metrics. To help inform this discussion, we assessed patient- and clinician-reported medication administration among nationally representative populations of patients with allergic rhinitis. Study Design Cross-sectional analyses. Setting and Subjects Home health assessments, ambulatory visits. Methods Participants in the National Health and Nutrition Examination Survey and the National Ambulatory Medical Care Survey / National Hospital Ambulatory Medical Care Survey were assessed. The primary outcomes were the percentage of patients reporting receipt of antihistamines and/or nasal steroids among those with allergy-related symptoms and the percentage for whom a clinician administered these medications when diagnosing allergic rhinitis. Secondary outcomes included assessments of those with worse quality of life, confirmatory allergy testing, and leukotriene receptor antagonist use. Results Within the National Health and Nutrition Examination Survey, an estimated 29.2 million patients were diagnosed with "hay fever," while 92.2 million were diagnosed with "allergies." Patients with symptoms of allergic rhinitis reported that antihistamines or nasal steroids were prescribed in 21.1% to 24.0% of cases. Leukotriene receptor antagonists were given to 1.7% of those without asthma or use of other allergy medications. Within the National Ambulatory Medical Care Survey / National Hospital Ambulatory Medical Care Survey, observations representing 149.5 million visits for allergic rhinitis demonstrated that nasal steroids were administered in 29.6% of cases, while nonsedating and sedating antihistamines were given in 22.4% and 17.2%, respectively. Conclusions Despite a high prevalence of allergic rhinitis, per patient report and clinician entry, a substantial number of affected patients do not receive antihistamines and nasal steroids.
authors: 1 Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, USA.
authors: Rachel E
authors: RE
authors: Roditi
authors: 2 Departments of Otolaryngology and Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors: Stacey
authors: S
authors: Ishman
authors: 3 University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors: Stella
authors: S
authors: Lee
authors: 4 Department of Otolaryngology, Johns Hopkins University, Baltimore, Maryland, USA.
authors: Sandra
authors: S
authors: Lin
authors: 1 Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, USA.
authors: Jennifer J
authors: JJ
authors: Shin
mesh_terms: D000328:Adult; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D005260:Female; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D058996:Quality Improvement; D011788:Quality of Life; D065631:Rhinitis, Allergic / Q000188:drug therapy*; D014481:United States
chemical_list: D018926:Anti-Allergic Agents; D018927:Anti-Asthmatic Agents; D006633:Histamine Antagonists; D020024:Leukotriene Antagonists
keywords: National Ambulatory Medical Care Survey; allergic rhinitis; antihistamines; nasal steroids; performance measures; practice patterns; prevalence; quality improvement