title: A comparison of outcome of medical and surgical treatment of migraine headache: In 1 year follow-up.
abstract: BACKGROUND
  This study was designed to compare the efficacy of the medical treatment versus the surgical treatment approach to decompression of trigger point nerves in patients with migraine headaches.
  
  
  METHODS
  Fifty volunteers were randomly assigned to the medical treatment group (n = 25) or the surgical treatment group (n = 25) after examination by the team neurologist to ensure a diagnosis of migraine headache. All patients received botulinum toxin type A to confirm the trigger sites. The surgical treatment group underwent surgical deactivation of the trigger site(s). The medical treatment group underwent prophylactic pharmacologic interventions by the neurologist. Pretreatment and 12-month posttreatment migraine headache frequency, duration, and intensity were analyzed and compared to determine the success of the treatments.
  
  
  RESULTS
  Nineteen of the 25 patients (76%) in the surgical treatment group and 10 of the 25 patients (40%) in the medical treatment group experienced a successful outcome (at least a 50% decrease in migraine frequency, duration, or intensity) after 1 year from surgery. Surgical treatment had a significantly higher success rate than medical treatment (P < 0.001). Nine patients (36%) in the surgical treatment group and one patient (4%) in the medical treatment group experienced cessation of migraine headaches. The elimination rate was significantly higher in the surgical treatment group than in the medical treatment group (P < 0.001).
  
  
  CONCLUSIONS
  Based on the 1-year follow-up data, there is strong evidence that surgical manipulation of one or more migraine trigger sites can successfully eliminate or reduce the frequency, duration, and intensity of migraine headaches in a lasting manner.
authors: Department of Aesthetic, Plastic and Reconstructive Surgery, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
authors: Mahmood
authors: M
authors: Omranifard
authors: Department of Aesthetic, Plastic and Reconstructive Surgery, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
authors: Hossein
authors: H
authors: Abdali
authors: Department of Aesthetic, Plastic and Reconstructive Surgery, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
authors: Mehdi Rasti
authors: MR
authors: Ardakani
authors: Department of Aesthetic, Plastic and Reconstructive Surgery, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
authors: Mohsen
authors: M
authors: Talebianfar
keywords: Medical treatment; migraine headache; migraine headache index; surgical treatment