title: Metastatic neuroendocrine carcinoma of aortic body origin in a cat.
abstract: An 8-year-old, female spayed Domestic Shorthair cat was presented to the Auburn University Emergency and Critical Care service for evaluation of pleural effusion and a suspected intrathoracic mass. Computed tomography was performed which confirmed the presence of a large intrathoracic mass, likely heart-based. Fine-needle aspirates were obtained and a cytologic diagnosis of a neuroendocrine tumor was made. Treatment with toceranib phosphate was briefly attempted at home by the owners. The cat died at home approximately 6 weeks after diagnosis. Necropsy and subsequent histopathologic examination revealed a metastatic neuroendocrine carcinoma of aortic body origin. Aortic body tumors are extremely rare in cats and to the authors' knowledge, a neuroendocrine carcinoma of aortic body origin with distant metastases has not yet been reported in a cat.
authors: Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, USA. szh0077@auburn.edu.
authors: Sonya C
authors: http://orcid.org/0000-0001-6791-2248
authors: SC
authors: Hansen
authors: Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
authors: Annette N
authors: AN
authors: Smith
authors: Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
authors: Kendon W
authors: KW
authors: Kuo
authors: Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
authors: Eric J
authors: EJ
authors: Fish
authors: Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
authors: Jey W
authors: JW
authors: Koehler
authors: Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
authors: Gisela
authors: G
authors: Martinez-Romero
authors: Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
authors: Lenore M
authors: LM
authors: Bacek
mesh_terms: D000818:Animals; D001016:Aortic Bodies / Q000473:pathology*; D044963:Biopsy, Fine-Needle; D018278:Carcinoma, Neuroendocrine / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis*; D002415:Cats; D005260:Female; D009206:Myocardium / Q000473:pathology*; D009362:Neoplasm Metastasis; D010996:Pleural Effusion
keywords: Chemodectoma; feline; histology; neoplasia