title: Drychampones A-C: Three Meroterpenoids from Dryopteris championii.
abstract: Three novel sesquiterpenoid-based meroterpenoids, drychampones A-C (1-3, respectively), were isolated from Dryopteris championii. Compounds 1 and 3 possessed a novel carbon skeleton which was constructed by an 11/6/6 ring system coupled with a pyronone moiety, and 1-3 were three racemates. Their structures and absolute configurations were elucidated by NMR, MS, and computational methods. The hypothetical biosynthetic pathways of these meroterpenoids and their antibacterial activities were also discussed.
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Neng-Hua
authors: NH
authors: Chen
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Yu-Bo
authors: YB
authors: Zhang
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Xiao-Jun
authors: XJ
authors: Huang
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Lin
authors: L
authors: Jiang
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Si-Qi
authors: SQ
authors: Jiang
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Guo-Qiang
authors: GQ
authors: Li
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Yao-Lan
authors: YL
authors: Li
authors: Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
authors: Guo-Cai
authors: GC
authors: Wang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D066241:Carbon-13 Magnetic Resonance Spectroscopy; D002942:Circular Dichroism; D032492:Dryopteris / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D066244:Proton Magnetic Resonance Spectroscopy; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D012717:Sesquiterpenes