title: c.428T > C (p.V143A) homozygous mutation in TP53 gene as a possible mechanism of resistance to trastuzumab therapy in gastric cancer.
authors: a Division of Oncology, ASST-Santi Paolo E Carlo , San Carlo Borromeo Hospital , Milan , Italy.
authors: Mauro
authors: M
authors: Moroni
authors: b Division of Surgery, ASST-Santi Paolo E Carlo , San Carlo Borromeo Hospital , Milan , Italy.
authors: Marco
authors: M
authors: Stella
authors: c Division of Oncology , IRCCS Fondazione Policlinico San Matteo , Pavia , Italy.
authors: Paolo
authors: P
authors: Pedrazzoli
authors: a Division of Oncology, ASST-Santi Paolo E Carlo , San Carlo Borromeo Hospital , Milan , Italy.
authors: Marco
authors: M
authors: Pirovano
authors: d Pathologic Anatomy Section, Department of Diagnostic Medicine , IRCCS Fondazione Policlinico San Matteo , Pavia , Italy.
authors: Emanuela
authors: E
authors: Boveri
authors: e Molecular Pathology Unit, Department of Laboratory Medicine , Niguarda Cancer Center, ASST- Grande Ospedale Metropolitano Niguarda , Milan , Italy.
authors: Silvio
authors: S
authors: Veronese
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000235:genetics; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D019008:Drug Resistance, Neoplasm / Q000187:drug effects / Q000235:genetics*; D005091:Exons; D005260:Female; D006720:Homozygote; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000556:secondary; D008875:Middle Aged; D009154:Mutation; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000235:genetics; D000068878:Trastuzumab / Q000008:administration & dosage / Q000627:therapeutic use*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*
chemical_list: C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; D000068878:Trastuzumab