title: Palladium-Catalyzed Enantioselective Heteroannulation of 1,3-Dienes by Functionally Substituted Aryl Iodides.
abstract: The first enantioselective heteroannulation of 1,3-dienes by 2-iodoanilines and 2-iodobenzylic alcohols is described. The application of a BINOL-derived phosphoramidite ligand bearing electron-withdrawing substituents is the key to obtaining high enantioselectivity. This protocol provides an efficient way to access optically active chiral indolines and isochromans from readily available starting materials.
authors: Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
authors: Shu-Sen
authors: SS
authors: Chen
authors: Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
authors: Jing
authors: J
authors: Meng
authors: Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
authors: Yu-Hui
authors: YH
authors: Li
authors: Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
authors: Zhi-Yong
authors: ZY
authors: Han