title: Clinical significance of fasting plasma glucose in patients with normal 50-g glucose challenge test in pregnancy: Is 100 bigger than 92?
abstract: The present study aimed to analyse the perinatal outcomes in patients with normal 50-g Glucose Challenge Test but who are considered retrospectively to have gestational diabetes mellitus based on elevated fasting plasma glucose (FPG) levels according to recent criteria. The study was conducted between January 2010 and December 2014 to identify patients with FPG values >92 mg/dl and GCT values <130 mg/dl. The patients were divided into two groups: those with FPG values between 92 and 99 mg/dl (Group 1) and those with FPG values >99 mg/dl (Group 2). The rate of obstetric complications was similar in the three groups, except for a higher rate of preeclampsia in Group 2 than in the control group (8.3% versus 3.1%; p = 0.031). The rate of large for gestational age neonates in Group 2 was 15%, which was higher than the rate in Group 1 (5.5%) and control group (7.4%) (p = 0.046 and p = 0.047, respectively). The rate of neonatal intensive care unit admissions in Group 2 was 11.7%, which was higher than the rate in Group 1 (3.1%) and in the control group (2.4%). Our findings indicate that there is a clinically recognisable difference in perinatal outcomes when a threshold of 100 mg/dl is used for FPG instead of 92 mg/dl.
authors: a Department of Perinatology, Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors: Korkut
authors: K
authors: Daglar
authors: a Department of Perinatology, Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors: Ozgür
authors: O
authors: Kara
authors: a Department of Perinatology, Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors: Gülenay Gençosmanolu
authors: GG
authors: Türkmen
authors: a Department of Perinatology, Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors: Ayse
authors: A
authors: Kırbas
authors: a Department of Perinatology, Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors: Ebru Hacer
authors: EH
authors: Biberoğlu
authors: a Department of Perinatology, Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors: Cem Yasar
authors: CY
authors: Sanhal
authors: a Department of Perinatology, Zekai Tahir Burak Research and Training Hospital , Ankara , Turkey.
authors: Nuri
authors: N
authors: Danisman
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D016022:Case-Control Studies; D016640:Diabetes, Gestational / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005865:Gestational Age; D005951:Glucose Tolerance Test / Q000379:methods / Q000592:standards; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D007744:Obstetric Labor Complications / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D010043:Outcome and Process Assessment, Health Care; D018743:Perinatal Care / Q000379:methods / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome; D014421:Turkey / Q000453:epidemiology
chemical_list: D001786:Blood Glucose
keywords: Fasting plasma glucose; gestational diabetes; glucose challenge test