title: Testosterone-induced "Virilization" of Mesonephric Duct Remnants and Cervical Squamous Epithelium in Female-to-Male Transgenders: A Report of 3 Cases.
abstract: Mesonephric ducts regress in genotypic females, leaving behind few remnants. These vestigial structures are often recognized in the mesosalpinx and paracervical regions. We report here 3 cases of female-to-male transgenders who underwent hysterectomy following testosterone treatment. Both female and male genital structures were identified on histologic examination. Although the morphologic appearances of the specimens were unremarkable, histologically 1 case revealed a well-formed fallopian tube as well as an epididymis and 2 cases showed prostate glands to be present in the cervical squamous epithelium.
authors: Department of Pathology, Women & Infants Hospital/Alpert Medical School of Brown University, Providence, Rhode Island.
authors: Kamaljeet
authors: K
authors: Singh
authors: C James
authors: CJ
authors: Sung
authors: W Dwayne
authors: WD
authors: Lawrence
authors: M Ruhul
authors: MR
authors: Quddus
mesh_terms: D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000033:anatomy & histology / Q000187:drug effects* / Q000502:physiology; D004822:Epididymis / Q000033:anatomy & histology; D004848:Epithelium / Q000033:anatomy & histology / Q000187:drug effects* / Q000502:physiology; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008297:Male; D011467:Prostate / Q000033:anatomy & histology; D057829:Gender-Affirming Procedures / Q000379:methods*; D013739:Testosterone / Q000008:administration & dosage*; D063106:Transgender Persons; D014928:Wolffian Ducts / Q000033:anatomy & histology / Q000187:drug effects* / Q000502:physiology
chemical_list: D013739:Testosterone