title: The Whole (Cell) Is Less Than the Sum of Its Parts.
abstract: Despite advances in metabolite profiling, a full picture of the metabolic landscape of the cell has been limited by sub-cellular compartmentalization, which segregates distinct nutrient pools into membrane-bound organelles. Now, Chen et al. describe methods for overcoming this hurdle and provide a new quantitative picture of the mitochondrial metabolome.
authors: Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
authors: Jonathan G
authors: JG
authors: Van Vranken
authors: Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84132, USA; Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT 84132, USA. Electronic address: rutter@biochem.utah.edu.
authors: Jared
authors: J
authors: Rutter
mesh_terms: D006801:Humans; D055442:Metabolome; D015388:Organelles / Q000378:metabolism*