title: Erecricins A-E, prenylated acylphloroglucinols from the roots of Hypericum erectum.
abstract: Six new prenylated acylphloroglucinols, erecricins A-E (1-5) and adotogirin (6), were isolated from the roots of Hypericum erectum (Hypericaceae). Their structures were assigned on the basis of spectroscopic evidences. Erecricins A-E (1-5) are bicyclic prenylated acylphloroglucinols possessing a chromane or a chromene skeleton. Adotogirin (6) is a simple achylphloroglucinol with an O-geranyl moiety. Antimicrobial activities of these acylphloroglucinols were also evaluated.
authors: Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan.
authors: Shuangxin
authors: S
authors: Lu
authors: Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan; Graduate School of Bioscience and Bioindustry, Tokushima University, Tokushima 770-8513, Japan. Electronic address: ntanak@tokushima-u.ac.jp.
authors: Naonobu
authors: N
authors: Tanaka
authors: Division of Immunobiology, Department of Pharmaceutical Sciences, International University of Health and Welfare, Tochigi 324-8501, Japan.
authors: Yutaka
authors: Y
authors: Tatano
authors: Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan. Electronic address: kasiwada@tokushima-u.ac.jp.
authors: Yoshiki
authors: Y
authors: Kashiwada
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D001419:Bacteria / Q000187:drug effects; D020902:Hypericum / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010696:Phloroglucinol / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry*; D054876:Prenylation
chemical_list: D000900:Anti-Bacterial Agents; C000613550:adotogirin; D010696:Phloroglucinol
keywords: Acylphloroglucinol; Adotogirin; Erecricins A–E; Hypericaceae; Hypericum erectum