title: Sperm proteome and reproductive technologies in mammals.
abstract: Sperm is highly differentiated cell that can be easily obtained and purified. Mature sperm is considered to be transcriptionally and translationally silent and incapable of protein synthesis. Recently, a large number of proteins have been identified in sperm from different species by using the proteomic approaches. Clinically, sperm proteins can be used as markers for male infertility due to different protein profiles identified in sperm from fertile and infertile male animals. Recent evidences have shown that the conditions of sperm preservation in vitro can also change the sperm protein profiles. This paper reviews the recent scientific publications available to address sperm proteome and their relationship with sperm cryopreservation, capacitation, fertilization, and separation of X and Y sperm. Future directions in the application of sperm proteomics to develop or optimize reproductive technologies in mammals are also discussed.
authors: College of Animal Sciences, Jilin University, 5333 Xian Road, Changchun 130062, PR China.
authors: Chun-Jin
authors: CJ
authors: Li
authors: The Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of Agriculture of China, Institute of Animal Science, Chinese Academy of Agriculture Sciences, Beijing 100193, PR China.
authors: Dong
authors: D
authors: Wang
authors: College of Animal Sciences, Jilin University, 5333 Xian Road, Changchun 130062, PR China. Electronic address: xzhou65@vip.sina.com.
authors: Xu
authors: X
authors: Zhou
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D008297:Male; D008322:Mammals / Q000502:physiology*; D020543:Proteome / Q000502:physiology*; D012098:Reproduction / Q000502:physiology*; D013094:Spermatozoa / Q000378:metabolism*; D059467:Transcriptome
chemical_list: D020543:Proteome
keywords: Fertilization; Proteomic technology; Sex control; Sperm cryopreservation; Sperm proteome