title: Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report.
abstract: A case of metastatic renal cell carcinoma (RCC) to the mandible is reported. A 22-year-old man consulted us for hypoesthesia of the right lower lip. Panorama X-ray film showed a radiolucent lesion in the right mandibular body. A diagnosis of a metastatic tumor to the mandible from the right kidney was made after evaluation by computed tomography and bone scan with Tc99 methyl diphosphonate which also revealed multiple bone metastases. Histologically diagnosis was clear cell variant of RCC. Patient has been put on radiotherapy for symptomatic treatment and a molecularly targeted drug. The therapy effectively stopped the progressive growth of oral and other metastatic lesions. The quality of life is relatively well maintained with tolerable adverse effects. The patient is still on our follow-up with an improved quality of life.
authors: Department of Oral and Maxillofacial Surgery, Government Dental College, Srinagar, Jammu and Kashmir, India.
authors: Ajaz
authors: A
authors: Shah
authors: Department of Oral and Maxillofacial Surgery, Government Dental College, Srinagar, Jammu and Kashmir, India.
authors: Shahi
authors: S
authors: Jahan
authors: Department of Oral and Maxillofacial Surgery, Government Dental College, Srinagar, Jammu and Kashmir, India.
authors: Latief
authors: L
authors: Najar
authors: Department of Oral and Maxillofacial Surgery, Government Dental College, Srinagar, Jammu and Kashmir, India.
authors: Shahid
authors: S
authors: Hassan
authors: Department of Oral and Maxillofacial Surgery, Government Dental College, Srinagar, Jammu and Kashmir, India.
authors: Manzoor
authors: M
authors: Mohammad
keywords: Clear cell variant of renal cell carcinoma; molecular targeted therapy; oral metastatic lesion