title: Factors related to fatigue after paediatric acquired brain injury (ABI).
abstract: OBJECTIVE
  To assess the degree of fatigue in children and youth after traumatic and non-traumatic brain injury (TBI and NTBI) and related factors.
  
  
  METHODS
  Follow-up study including patients with a hospital-based diagnosis of acquired brain injury (ABI), aged 4-20 years at onset and their parents. Parents and children (dependent on age) completed the Paediatric Quality of Life Inventory™ Multidimensional Fatigue Scale (PedsQL™ MFS), which measures general fatigue (GF), sleep/rest fatigue (SRF) and cognitive fatigue (CF). Additional assessments included the Child & Family Follow-up Survey (CFFS) and PedsQL™ 4.0 General Core Scales and sociodemographic and disease characteristics.
  
  
  RESULTS
  Eighty-eight parents completed the PedsQL™ MFS 24-30 months after diagnosis, with 49/88 patients (56%) completing the child version. The median age of the patients was 11 years (interquartile range [IQR] = 7). There were 69 patients with TBI (16% moderate/severe TBI) and 19 patients with NTBI (16% moderate/severe NTBI). The median parent-reported and child-reported PedsQL™ MFS Total Scale Scores were 76.5 (SD = 16.4) and 78.5 (12.9), respectively (Spearman r = 0.450, p = 0.001). Apart from NTBI, increasing age and a single-parent household were significantly associated with more fatigue according to the parent-reported PedsQL™ MFS Total Score (and/or one or more sub-scale scores).
  
  
  CONCLUSIONS
  Two years after onset, in particular, the parent-reported fatigue after NTBI was considerable. Moreover, older children and children from a single-parent household were found to have higher fatigue levels.
authors: a Sophia Rehabilitation , The Hague , The Netherlands.
authors: F
authors: F
authors: van Markus-Doornbosch
authors: a Sophia Rehabilitation , The Hague , The Netherlands.|b The Hague University of Applied Sciences , The Hague , The Netherlands.
authors: A J
authors: AJ
authors: de Kloet
authors: b The Hague University of Applied Sciences , The Hague , The Netherlands.
authors: M A M
authors: MA
authors: Berger
authors: c Revant Rehabilitation Centre , Breda , The Netherlands.|d Department of Rehabilitation Medicine , Erasmus University Medical Centre , Rotterdam , The Netherlands.
authors: S A M
authors: SA
authors: Lambregts
authors: e Department of Medical Statistics , Leiden University Medical Centre , Leiden , The Netherlands.
authors: R
authors: R
authors: Wolterbeek
authors: a Sophia Rehabilitation , The Hague , The Netherlands.|f Department of Orthopaedics , Leiden University Medical Centre, Rehabilitation and Physical Therapy , Leiden , The Netherlands.|g Rijnlands Rehabilitation Centre , Leiden , The Netherlands.
authors: T P M
authors: TP
authors: Vliet Vlieland
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001930:Brain Injuries / Q000150:complications* / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D004777:Environment; D005221:Fatigue / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006761:Hospitals; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications; D010290:Parents / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology; D055815:Young Adult
keywords: Health-related quality-of-life; acquired brain injury; fatigue; paediatrics; participation