title: Transition-Metal-Catalyzed Hydrosulfoximination and Oxidation Reaction for the Synthesis of Sulfoximine Derivatives.
abstract: We report herein a Au/Ag-cocatalyzed chemoselective hydrosulfoximination reaction of simple ynamides with free NH-sulfoximines, which produces the N-alkenylated sulfoximidoyl derivatives with quantitative atom efficiency and good to excellent yields. Further elaborations of the enamine isomers under Ru-catalyzed oxidative conditions to cleave the C═C double bonds can selectively afford urea-type sulfoximines. The aforementioned catalytic reactions provide new opportunities for the convergent and straightforward access to sulfoximine derivatives.
authors: Key Laboratory of Functional Small Organic Molecules, Ministry of Education, and College of Chemistry & Chemical Engineering, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.
authors: Zhiyuan
authors: Z
authors: Chen
authors: Key Laboratory of Functional Small Organic Molecules, Ministry of Education, and College of Chemistry & Chemical Engineering, Jiangxi Normal University , Nanchang, Jiangxi 330022, People's Republic of China.
authors: Jiapian
authors: J
authors: Huang
authors: Caohejing Community Health Service Center , 38 Binyang Road, Shanghai 200235, People's Republic of China.
authors: Zhijie
authors: Z
authors: Wang