title: Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy.
abstract: Prostatectomy is associated with short- and long-term morbidity, which includes attenuation of muscle function and deterioration of lean body mass. Physical function is a known predictor of morbidity and mortality, with initial evidence indicating that presurgical exercise is associated with fewer postsurgical complications and shorter hospitalization. The aim was to determine the feasibility of a supervised presurgical exercise program for prostate cancer (PCa) patients scheduled for prostatectomy.
  
  
  
  Ten men (68+6.4 years old) with localized PCa undertook a 6-week resistance and aerobic exercise program prior surgery. Training was undertaken twice weekly and patients were assessed at baseline, presurgery, and 6 weeks postsurgery. Outcome measures included muscle and physical performance, body composition, urinary incontinence and questionnaire.
  
  
  
  Muscle strength increased by 7.5% to 24.3% ( P < .05) from baseline to presurgery but decreased to pretraining levels postsurgery, except for knee extensor strength ( P = .247). There were significant improvements ( P < .05) in the 6-m fast walk (9.3%), 400-m walk (7.4%), and chair rise (12.3%) at presurgery. Following surgery, improvements in physical performance were maintained. There was no change in lean or fat mass prior to surgery, but lean mass declined by 2.7 kg ( P = .014) following surgery. There were no adverse effects from the exercise program.
  
  
  
  Exercise undertaken prior to prostatectomy improved muscle and physical performance, with functional benefits maintained 6 weeks postsurgery. Presurgical exercise for PCa patients has the potential to facilitate recovery by improving physical reserve capacity, especially in men with poor muscle nd physical performance.
authors: 1 Edith Cowan University, Joondalup, WA, Australia.
authors: Favil
authors: F
authors: Singh
authors: 1 Edith Cowan University, Joondalup, WA, Australia.
authors: Robert U
authors: RU
authors: Newton
authors: 2 University of Sydney, NSW, Australia.|3 Australian Catholic University, NSW, Australia.
authors: Michael K
authors: MK
authors: Baker
authors: 1 Edith Cowan University, Joondalup, WA, Australia.|4 Sir Charles Gairdner Hospital, Nedlands, WA, Australia.|5 University of Western Australia, Nedlands, WA, Australia.
authors: Nigel A
authors: NA
authors: Spry
authors: 1 Edith Cowan University, Joondalup, WA, Australia.|6 University of Wollongong, NSW, Australia.
authors: Dennis R
authors: DR
authors: Taaffe
authors: 7 Saint John of God Murdoch Hospital, Murdoch, WA, Australia.
authors: Jeffery
authors: J
authors: Thavaseelan
authors: 1 Edith Cowan University, Joondalup, WA, Australia.
authors: Daniel A
authors: DA
authors: Galvão
mesh_terms: D000368:Aged; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D010807:Physical Endurance / Q000502:physiology; D010809:Physical Fitness / Q000502:physiology; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000503:physiopathology*; D014549:Urinary Incontinence / Q000503:physiopathology
keywords: exercise; incontinence; prehabilitation; prostate cancer; prostatectomy; surgery