title: MicroRNAs in Allergic Disease.
abstract: MicroRNAs (miRNAs) are short, single-stranded, non-coding RNAs that are increasingly being recognized as important epigenetic regulators. They have been implicated in the pathogenesis of many diseases including cancer, cardiovascular diseases, connective tissue diseases, and neuromuscular disorders.
  
  
  
  A few miRNAs have already been recognized as a core set of miRNAs important in allergic inflammation. These include let-7, miR-21, miR-142, and miR-146. This review aims to bring together some of the recent findings on how miRNAs regulate allergic inflammation with special focus on asthma, atopic dermatitis, allergic rhinitis, and eosinophilic esophagitis. We will also touch upon extracellular miRNAs and future perspective of this field of study.
authors: Department of Pediatrics, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8670, Japan.
authors: Eishika
authors: E
authors: Dissanayake
authors: Department of General Medical Science, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8670, Japan. yuzaburo@chiba-u.jp.
authors: Yuzaburo
authors: Y
authors: Inoue
mesh_terms: D057765:Eosinophilic Esophagitis / Q000503:physiopathology*; D006801:Humans; D007249:Inflammation; D035683:MicroRNAs / Q000502:physiology*; D065631:Rhinitis, Allergic / Q000235:genetics*
chemical_list: D035683:MicroRNAs
keywords: Allergic rhinitis; Asthma; Atopic dermatitis; Eosinophilic esophagitis; Inflammation; microRNAs