title: Immunomodulatory effects of turmeric: Proliferation of spleen cells in mice.
abstract: Experiments were conducted to examine the effects of turmeric on spleen cell proliferation. Cell suspensions of spleen cells from young and aged mice were treated with or without conconavalin A (Con-A) as a proliferation stimulant, and with and without turmeric (20 mg/mL) in different concentrations. Spleen cells from young mice that received turmeric showed significant increase in spleen cell proliferation (P < 0.05), while spleen cells from aged mice that received turmeric showed no significant increase in T lymphocytes. The data indicates that turmeric increases the ability of spleen cells in young mice to proliferate, in vitro.
authors: a Indiana University School of Medicine , Indianapolis , Indiana , USA.|b Department of Biology , Indiana University-Purdue University Fort Wayne , Fort Wayne , Indiana , USA.
authors: Rafid
authors: R
authors: Mustafa
authors: b Department of Biology , Indiana University-Purdue University Fort Wayne , Fort Wayne , Indiana , USA.
authors: Elliott
authors: E
authors: Blumenthal
mesh_terms: D000818:Animals; D049109:Cell Proliferation / Q000187:drug effects; D003208:Concanavalin A / Q000494:pharmacology; D030024:Curcuma / Q000737:chemistry*; D056747:Immunomodulation; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D010936:Plant Extracts / Q000737:chemistry / Q000276:immunology* / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology* / Q000187:drug effects* / Q000276:immunology; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology
chemical_list: D010936:Plant Extracts; D003208:Concanavalin A
keywords: in vitro; mice; proliferation; spleen; spleen cell proliferation; turmeric