title: Association between choroidal thickness and anterior chamber segment in eyes with narrow or open-angle.
abstract: OBJECTIVE
  To investigate the relationship between choroidal thickness and anterior chamber segment in subjects with eyes with narrow or open-angle.
  
  
  METHODS
  The subfoveal choroidal thickness was measured with enhanced depth-imaging optical coherence tomography and anterior chamber parameters were measured with ultrasound biomicroscopy in one eye of 23 subjects with open-angle eyes and 38 subjects with narrow-angle eyes. The mean age was 59.52±7.04y for narrow-angle subjects and 60.76±7.23y for open-angle subjects (P=0.514). Multivariate linear regression analysis was performed to assess the association between choroidal thickness and narrow-angle parameters.
  
  
  RESULTS
  There were no differences in subfoveal choroidal thickness between open- and narrow-angle subjects (P=0.231). Anterior chamber parameters, including central anterior chamber depth, trabecular iris angle, iris thickness 500 µm from the scleral spur (IT500), and ciliary body thickness at 1 mm and 2 mm from the scleral spur (CBT1, CBT2) showed significant differences between the two groups (P<0.05). Subfoveal choroidal thickness showed negative correlation (β=-0.496, P=0.016) only with anterior chamber depth in the open-angle group and with age (β=-0.442, P=0.003) and IT500 (β=-0.399, P=0.008) in the narrow-angle group. However, subfoveal choroidal thickness was not correlated with trabecular iris angle, anterior chamber depth, ciliary body thickness, or central corneal thickness in the narrow-angle group.
  
  
  CONCLUSIONS
  Choroidal thickness does not differ in the two groups and has not correlated with anterior chamber parameters in narrow-angle subjects, suggesting a lack of relationship between choroidal thickness and primary angle-closure glaucoma.
authors: Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: Song-Feng
authors: SF
authors: Li
authors: Department of Ophthalmology, Beijing Shi Jing Shan Hospital, Beijing 100000, China.
authors: Ge-Wei
authors: GW
authors: Wu
authors: Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: Chang-Xi
authors: CX
authors: Chen
authors: Department of Ophthalmology, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.
authors: Ling
authors: L
authors: Shen
authors: Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: Zhi-Bao
authors: ZB
authors: Zhang
authors: Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: Fei
authors: F
authors: Gao
authors: Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: Ning-Li
authors: NL
authors: Wang
keywords: choroidal thickness; narrow-angle eye; optical coherence tomography; primary angle-closure glaucoma