title: Copper-Mediated Oxidative Fluorination of Aryl Stannanes with Fluoride.
abstract: A regiospecific method for the oxidative fluorination of aryl stannanes using tetrabutylammonium triphenyldifluorosilicate (TBAT) and copper(II) triflate is described. This reaction is robust, uses readily available reagents, and proceeds via a stepwise protocol under mild conditions (60 °C, 3.2 h). Broad functional group tolerance, including arenes containing protic and nucleophilic groups, is demonstrated.
authors: Department of Chemistry and Biochemistry, University of California, Los Angeles , 607 Charles E. Young Drive East, Los Angeles, California 90095, United States.
authors: Raymond F
authors: RF
authors: Gamache
authors: Department of Molecular and Medical Pharmacology and Crump Institute for Molecular Imaging, David Geffen School of Medicine, University of California, Los Angeles , 570 Westwood Plaza, Los Angeles, California 90095, United States.
authors: Christopher
authors: C
authors: Waldmann
authors: Department of Molecular and Medical Pharmacology and Crump Institute for Molecular Imaging, David Geffen School of Medicine, University of California, Los Angeles , 570 Westwood Plaza, Los Angeles, California 90095, United States.
authors: Jennifer M
authors: JM
authors: Murphy