title: A rare case of concurrent signet-ring carcinoma of breast and microangiopathic hemolytic anemia.
abstract: Microangiopathic hemolytic anemia (MAHA) can be an uncommon presentation of an underlying malignancy, most often due to signet-ring cell carcinoma (SRCC). Additionally, pure SRCC in a breast primary-tumor comprises <2% of all breast cancers (Shin SY, Park H, Chae SW, Woo HY. Microangiopathic hemolytic anemia as the first manifestation of metastatic signet-ring cell carcinoma of unknown origin: a case report and review of literature. Kor J Lab Med 2011;31:157-61). To the best of our knowledge, the combination of these two entities, pure breast primary SRCC along with MAHA, has not been reported. Here, we present such a rare case. We also evaluate the current literature regarding this and similar disease processes, of which evidence is scarce and further research is needed.
authors: General Surgery, Arrowhead Regional Medical Center, Colton, CA 92345, USA kallara5685@gmail.com.
authors: Kelly
authors: K
authors: Lara
authors: General Surgery, Arrowhead Regional Medical Center, Colton, CA 92345, USA.
authors: Esther
authors: E
authors: Bae
authors: General Surgery, Arrowhead Regional Medical Center, Colton, CA 92345, USA.
authors: Hanna
authors: H
authors: Park
authors: General Surgery, Arrowhead Regional Medical Center, Colton, CA 92345, USA.
authors: Farabi
authors: F
authors: Hussain