title: Predicting revision sinus surgery in allergic fungal and eosinophilic mucin chronic rhinosinusitis.
abstract: Chronic rhinosinusitis consists of several disease processes. Eosinophilic mucin is found in the subtypes of allergic fungal sinusitis (AFS) and eosinophilic mucin chronic rhinosinusitis (EMCRS). These entities frequently require surgical intervention and have high recurrence rates.
  
  
  
  We aimed to determine factors in patients with AFS and EMCRS that may be associated with a higher rate of revision surgeries. Our hypothesis is that patients who have polyps, high Lund-Mackay score (LMS), and fungus may have higher revision rates.
  
  
  
  Retrospective cohort study.
  
  
  
  This is a retrospective analysis of 117 patients identified over a 5-year period (2005-2009) with the diagnosis of AFS or EMCRS. Contingency tables were created to obtain the odds ratios estimates, and 95% confidence intervals were used to access the association between the outcome (having revision surgery or not) and other clinical binary predictors.
  
  
  
  Twenty-six of 117 (22%) of the study patients underwent revision surgery. Within the 2-year follow-up period, an additional five of 26 (19%) required another revision surgery. Average LMS was slightly higher in those who underwent revision surgery (16 vs. 13) on a scale of 0 to 24, with an overall mean score of 18 and standard deviation of 6.82 for the whole sample (117). Other factors evaluated were the presence of fungus, polyps, eosinophilic mucin, and the eosinophilic count and medical therapy received.
  
  
  
  The presence of eosinophilic mucin was significantly associated a higher rate of revision surgery.
  
  
  
  4. Laryngoscope, 127:59-63, 2017.
authors: Division of Pediatric Otolaryngology, Department of Otolaryngology-Head & Neck Surgery, University of Miami, Miami, Florida, U.S.A.
authors: Ramzi T
authors: RT
authors: Younis
authors: Department of Otolaryngology-Head & Neck Surgery, Jackson Memorial Hospital-University of Miami, Miami, Florida, U.S.A.
authors: Jamal
authors: J
authors: Ahmed
mesh_terms: D002908:Chronic Disease; D004804:Eosinophils / Q000276:immunology / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000276:immunology; D009181:Mycoses / Q000276:immunology* / Q000382:microbiology* / Q000601:surgery*; D009298:Nasal Polyps / Q000276:immunology / Q000601:surgery; D012086:Reoperation / Q000706:statistics & numerical data*; D012130:Respiratory Hypersensitivity / Q000276:immunology* / Q000382:microbiology*; D012189:Retrospective Studies; D012220:Rhinitis / Q000276:immunology* / Q000382:microbiology* / Q000601:surgery*; D012852:Sinusitis / Q000276:immunology* / Q000382:microbiology* / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D009077:Mucins
keywords: Allergic fungal sinusitis (AFS); Lund-Mackay score (LMS); eosinophilic mucin chronic rhinosinusitis (EMCRS)