title: Pulmonary Endarterectomy. Patient Selection, Technical Challenges, and Outcomes.
abstract: In chronic thromboembolic pulmonary hypertension, thromboemboli do not undergo resolution but instead become highly organized and fibrotic, resulting in obstruction of segments of the pulmonary vascular tree. Progressive pulmonary hypertension ensues, with substantial associated morbidity and mortality. Despite advances in medical therapy for some types of pulmonary hypertension, surgical pulmonary endarterectomy, also referred to as pulmonary thromboendarterectomy, remains the only potentially curative option for patients with chronic thromboembolic pulmonary hypertension. This article reviews patient selection, surgical technique, and outcomes for pulmonary endarterectomy in this patient population.
authors: 1 Department of Cardiothoracic Surgery, University of California, San Diego, La Jolla, California.
authors: Michael
authors: M
authors: Madani
authors: 2 Department of Thoracic Surgery, Kerckhoff-Klinik, Bad Nauheim, Germany.
authors: Eckhard
authors: E
authors: Mayer
authors: 3 Department of Thoracic Surgery, Centre Chirugical Marie Lannelongue, Le Plessis-Robinson, Île-de-France, France; and.
authors: Elie
authors: E
authors: Fadel
authors: 4 Department of Cardiothoracic Surgery, Papworth Hospital National Health Service Foundation Trust, Cambridge, Cambridgeshire, United Kingdom.
authors: David P
authors: DP
authors: Jenkins
mesh_terms: D002908:Chronic Disease; D004691:Endarterectomy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000601:surgery*; D018579:Patient Selection; D011182:Postoperative Care; D011183:Postoperative Complications; D011651:Pulmonary Artery / Q000601:surgery*; D011655:Pulmonary Embolism / Q000150:complications* / Q000601:surgery*; D016896:Treatment Outcome
keywords: hypertension; pulmonary; pulmonary embolism; pulmonary heart disease; venous thromboembolism