title: Ameliorative Effects of Dietary Selenium Against Cadmium Toxicity Is Related to Changes in Trace Elements in Chicken Kidneys.
abstract: The ameliorative effects of selenium (Se) against cadmium (Cd)-induced toxicity have been reported extensively. However, few studies have assessed the effects of multiple ions simultaneously on the variations of elements. In this study, the changes in Se, Cd, and 26 other element concentrations were investigated in chicken kidneys. One hundred and twenty-eight 31-week-old laying hens were fed a diet supplemented with either Se, Cd, or both Se and Cd for 90 days. The ion content was analyzed by inductively coupled plasma mass spectrometry (ICP-MS). We found that the Se, Cd, and combined Se and Cd treatments significantly affected the trace elements in the chicken kidneys. The Cd supplement caused ion profile disorders, including reduced concentrations of V, Cr, Mn, Mo, As, Ba, Hg, Ti, and Pb and increased Si, Cu, Li, Cd, and Sb. The Se supplement reduced the contents of Co, Mo, and Pb and increased the contents of Cr, Fe, and Se. Moreover, Se also increased the concentrations of Cr, Mn, Zn, and Se and decreased those of Li and Pb, which in contrast were induced by Cd. Complex interactions between elements were analyzed, and both positive and negative correlations among these elements are presented. The present study indicated that Se can help against the negative effects of Cd and may be related to the homeostasis of the trace elements in chicken kidneys.
authors: College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
authors: Runxiang
authors: R
authors: Zhang
authors: College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
authors: Yanan
authors: Y
authors: Wang
authors: College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
authors: Chao
authors: C
authors: Wang
authors: College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
authors: Peng
authors: P
authors: Zhao
authors: College of Life Science, Northeast Agricultural University, Harbin, 150030, People's Republic of China.
authors: Huo
authors: H
authors: Liu
authors: College of Life Science, Northeast Agricultural University, Harbin, 150030, People's Republic of China. jhlineau@126.com.
authors: Jianhong
authors: J
authors: Li
authors: College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People's Republic of China. jbao@neau.edu.cn.
authors: Jun
authors: J
authors: Bao
mesh_terms: D000818:Animals; D002104:Cadmium / Q000378:metabolism / Q000633:toxicity*; D002105:Cadmium Poisoning / Q000517:prevention & control*; D002645:Chickens / Q000378:metabolism*; D019587:Dietary Supplements; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism*; D013058:Mass Spectrometry; D012643:Selenium / Q000008:administration & dosage* / Q000378:metabolism / Q000494:pharmacology*; D014131:Trace Elements / Q000378:metabolism*
chemical_list: D014131:Trace Elements; D002104:Cadmium; D012643:Selenium
keywords: Cadmium; Kidney; Laying hens; Selenium; Trace element