title: Prognostic Value of Admission Blood Glucose in Diabetic and Non-diabetic Patients with Intracerebral Hemorrhage.
abstract: We aimed to validate prognostic value of elevated admission blood glucose (ABG) for clinical outcomes in diabetic and non-diabetic patients with intracerebral hemorrhage (ICH) in a representative large cohort. Data of ICH patients with onset time ≤24 h were derived from the China National Stroke Registry. Clinical outcomes included 3-month poor outcome (death or dependency) and death. Logistic regression was performed for the association between ABG and clinical outcomes, both in the entire cohort and in patients with and without diabetes mellitus. 2951 ICH patients were enrolled, including 267 (9.0%) diabetics. In the entire cohort, there was a trend to increased risk of poor outcome with increasing ABG levels (adjusted OR 1.09; 95% CI, 1.04-1.15; P < 0.001). The risk of poor outcome was significantly greatest for the highest quartile (≥7.53 mmol/L) of ABG (adjusted OR 1.54; 95% CI, 1.17-2.03; p = 0.002, P for trend 0.004). We got similar association in non-diabetics but not in diabetics. Elevated ABG confers a higher risk of poor outcome in non-diabetics than diabetics with similar glucose level. Elevated ABG is an independent predictor of 3-month poor outcome in ICH patients, the prognostic value of which is greater in non-diabetics than diabetics with similar glucose level.
authors: Department of Neurology, The Second Hospital, Hebei Medical University, Shi Jiazhuang, Hebei Province, China.
authors: Shichao
authors: S
authors: Sun
authors: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.|Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.
authors: Yuesong
authors: Y
authors: Pan
authors: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Centre for Neurological Diseases, Beijing, China.|Centre of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors: Xingquan
authors: X
authors: Zhao
authors: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Centre for Neurological Diseases, Beijing, China.|Centre of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors: Liping
authors: L
authors: Liu
authors: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Centre for Neurological Diseases, Beijing, China.|Centre of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors: Hao
authors: H
authors: Li
authors: Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.
authors: Yan
authors: Y
authors: He
authors: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Centre for Neurological Diseases, Beijing, China.|Centre of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors: Yilong
authors: Y
authors: Wang
authors: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Centre for Neurological Diseases, Beijing, China.|Centre of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors: Yongjun
authors: Y
authors: Wang
authors: Department of Neurology, The Second Hospital, Hebei Medical University, Shi Jiazhuang, Hebei Province, China.
authors: Li
authors: L
authors: Guo
mesh_terms: D000368:Aged; D001786:Blood Glucose; D002543:Cerebral Hemorrhage / Q000097:blood* / Q000503:physiopathology; D002681:China; D003920:Diabetes Mellitus / Q000097:blood* / Q000503:physiopathology; D003955:Diagnostic Tests, Routine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis
chemical_list: D001786:Blood Glucose