title: Salt Intake, Home Blood Pressure, and Perinatal Outcome in Pregnant Women.
abstract: BACKGROUND
  The relationship between salt (sodium chloride) intake and pregnancy-induced hypertension (PIH) remains unclear. The aim of this study was therefore to investigate the current status of salt intake during pregnancy and identify effective predictors for PIH.
  
  
  RESULTS
  Participants were 184 pregnant women who collected 24-h home urine as well as early morning urine samples. We investigated urinary salt excretion, home blood pressure (HBP) measurements for 7 consecutive days before the 20th and after the 30th gestational week, and the development of PIH. Urinary salt excretion according to early morning urine before the 20th gestational week was 8.6±1.7 g/day, and was significantly correlated with that measured from 24-h collected urine. Early morning urine estimated urinary salt excretion was slightly but significantly increased during pregnancy. HBP was 102±10/63±8 mmHg before the 20th gestational week and 104±12/64±10 mmHg after the 30th gestational week. On multiple regression analysis, serum uric acid and body mass index, but not urinary salt excretion, contributed to HBP both before the 20th and after the 30th gestational week. Fourteen participants (7.6%) developed PIH. On multivariate analysis, higher HBP and older age, but not urinary salt excretion, were significantly associated with PIH.
  
  
  CONCLUSIONS
  Higher HBP and older age, but not urinary salt excretion, are predictors of PIH. (Circ J 2016; 80: 2165-2172).
authors: Clinical Research Institute, National Hospital Organization Kyushu Medical Center.
authors: Minako
authors: M
authors: Inoue
authors: Takuya
authors: T
authors: Tsuchihashi
authors: Yasuyuki
authors: Y
authors: Hasuo
authors: Masanobu
authors: M
authors: Ogawa
authors: Mitsuhiro
authors: M
authors: Tominaga
authors: Kimika
authors: K
authors: Arakawa
authors: Emi
authors: E
authors: Oishi
authors: Satoko
authors: S
authors: Sakata
authors: Toshio
authors: T
authors: Ohtsubo
authors: Kiyoshi
authors: K
authors: Matsumura
authors: Takanari
authors: T
authors: Kitazono
mesh_terms: D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000097:blood / Q000652:urine; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D017673:Sodium Chloride, Dietary / Q000008:administration & dosage*; D014527:Uric Acid / Q000097:blood*
chemical_list: D017673:Sodium Chloride, Dietary; D014527:Uric Acid