title: Effects of a 1-year randomised controlled trial of resistance training on blood lipid profile and chylomicron concentration in older men.
abstract: OBJECTIVE
  Resistance exercise is promoted in older adults for its ability to improve muscle mass, strength and, hence, in reducing falls. However, its effects on blood lipids and CVD risk are less well established, particularly in this age group. This study aimed to investigate whether a 1-year resistance exercise program improves lipid profile and chylomicron concentration in older men.
  
  
  METHODS
  Participants were randomised to either three, 1 h resistance training sessions per week (RE) or an active control group [asked to undertake three 30 min walking sessions per week (AC)]. Fasting blood samples were collected at 0, 6, and 12 months for determination of lipid profile and glycaemic control. Diet, morphological and activity data were also collected at these time points.
  
  
  RESULTS
  Following 12 months, the RE intervention group had greater improvements in cholesterol profile; LDL-cholesterol concentration significantly decreased by 0.2 (0.2) mM [mean (SEM)] compared to control (P < 0.05). The RE group also exhibited a significant increase in lean body mass of 0.9 (1.3) kg after 12 months compared to the AC group (P < 0.05). There was no treatment or time effect on other anthropometric measures or fasting triacylglycerol, glucose, insulin or chylomicron concentrations.
  
  
  CONCLUSIONS
  The observed improvements in lean body mass and cholesterol profile promote the implementation of a resistance exercise intervention in this population.
authors: Faculty of Health Sciences, School of Public Health, Curtin University, Perth, WA, Australia. T.P.James@curtin.edu.au.|Curtin Health Innovation Research Institute, Curtin University, Perth, WA, Australia. T.P.James@curtin.edu.au.
authors: Anthony P
authors: http://orcid.org/0000-0002-0873-3714
authors: AP
authors: James
authors: Faculty of Health Sciences, School of Public Health, Curtin University, Perth, WA, Australia.
authors: Joanna
authors: J
authors: Whiteford
authors: School of Sport Science, Exercise and Health, The University of Western Australia, Perth, WA, Australia.
authors: Timothy R
authors: TR
authors: Ackland
authors: Faculty of Health Sciences, School of Public Health, Curtin University, Perth, WA, Australia.|Curtin Health Innovation Research Institute, Curtin University, Perth, WA, Australia.
authors: Satvinder S
authors: SS
authors: Dhaliwal
authors: School of Sport Science, Exercise and Health, The University of Western Australia, Perth, WA, Australia.
authors: Jenni J
authors: JJ
authors: Woodhouse
authors: Faculty of Health Sciences, School of Public Health, Curtin University, Perth, WA, Australia.|School of Medicine and Pharmacology, The University of Western Australia, Perth, WA, Australia.|Department of Diabetes and Endocrinology, Sir Charles Gairdner Hospital, 1st Floor, C Block, Perth, WA, 6009, Australia.
authors: Richard L
authors: RL
authors: Prince
authors: School of Medicine, Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, SA, Australia.
authors: Xingqiong
authors: X
authors: Meng
authors: Faculty of Health Sciences, School of Public Health, Curtin University, Perth, WA, Australia.
authors: Deborah A
authors: DA
authors: Kerr
mesh_terms: D000273:Adipose Tissue / Q000502:physiology*; D050154:Adiposity / Q000502:physiology*; D000368:Aged; D000369:Aged, 80 and over; D001835:Body Weight / Q000502:physiology*; D053298:Chylomicron Remnants / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008137:Longitudinal Studies; D008297:Male; D054526:Men's Health; D008875:Middle Aged; D055070:Resistance Training / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D053298:Chylomicron Remnants; D008055:Lipids
keywords: Cardiovascular disease risk; Chylomicron; Exercise; Lipid; Strength training