title: A New 5(6→7)abeo-sterol from the twigs of Podocarpus fleuryi.
abstract: A new 5(6→7)abeo-sterol with rarely reported [6-5-6-5]-fused rings, 3β,5β,6-trihydroxyl-B-norsitostane (1), along with 10 known compounds were isolated from the twigs of Podocarpus fleuryi. Their structures were elucidated by means of extensive spectroscopic analysis. Compound 1 was assessed for their cytotoxicity against five human tumour cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and the result showed that it had no activity.
authors: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming , China.
authors: Juan
authors: J
authors: Liu
authors: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming , China.
authors: Caiqiong
authors: C
authors: Yang
authors: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming , China.
authors: Junjie
authors: J
authors: Zhang
authors: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming , China.
authors: Jichun
authors: J
authors: Wu
authors: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming , China.
authors: Yegao
authors: Y
authors: Chen
mesh_terms: D000972:Antineoplastic Agents, Phytogenic; D045744:Cell Line, Tumor; D002681:China; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D028223:Pinus / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013261:Sterols / Q000737:chemistry* / Q000494:pharmacology
chemical_list: C000617920:3beta,5beta,6-trihydroxyl-B-norsitostane; D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D013261:Sterols
keywords: Podocarpaceae; Podocarpus fleuryi; abeo-sterol