title: Changes in the clinical presentation of patients with rheumatoid arthritis from the early 1990s to the years 2010: earlier identification but more severe patient reported outcomes.
authors: Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
authors: Wouter P
authors: WP
authors: Nieuwenhuis
authors: Department of Medical Humanities, VU University, Amsterdam, The Netherlands.
authors: Maarten Pt
authors: MP
authors: de Wit
authors: Division of Rheumatology, Department of Internal Medicine, Maastricht University Medical Center and CAPHRI, Maastricht University, Maastricht, The Netherlands.
authors: Annelies
authors: A
authors: Boonen
authors: Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
authors: Annette Hm
authors: AH
authors: van der Helm-van Mil
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D010147:Pain Measurement; D000071066:Patient Reported Outcome Measures; D010808:Physical Examination / Q000379:methods; D016059:Range of Motion, Articular / Q000502:physiology*; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors
chemical_list: D018501:Antirheumatic Agents
keywords: Disease Activity; Patient perspective; Rheumatoid Arthritis