title: Non-IgG4-related Multifocal Fibrosclerosis.
abstract: Multifocal fibrosclerosis (MFS), which causes systemic and chronic connective tissue inflammation, has been associated with IgG4 and regarded as an identical entity with "IgG4-related disease (IgG4-RD)". Although a few cases of MFS mimicking IgG4-RD histopathologically, despite the absence of a serum IgG4 elevation and IgG4-positive plasma cell infiltration, have been reported, there is, so far, little information regarding such exceptional cases. We herein demonstrate a case of non-IgG4-related MFS presenting with periaortitis and parotiditis, whose histological findings were consistent with IgG4-RD despite the absence of elevated serum and tissue IgG4 levels.
authors: Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Japan.
authors: Yosuke
authors: Y
authors: Kunishita
authors: Ryusuke
authors: R
authors: Yoshimi
authors: Mitsuhiro
authors: M
authors: Takeno
authors: Shoji
authors: S
authors: Yamanaka
authors: Yumiko
authors: Y
authors: Sugiyama
authors: Naomi
authors: N
authors: Tsuchida
authors: Daiga
authors: D
authors: Kishimoto
authors: Reikou
authors: R
authors: Kamiyama
authors: Kaoru
authors: K
authors: Minegishi
authors: Maasa
authors: M
authors: Hama
authors: Yohei
authors: Y
authors: Kirino
authors: Yoshiaki
authors: Y
authors: Ishigatsubo
authors: Atsuhisa
authors: A
authors: Ueda
authors: Hideaki
authors: H
authors: Nakajima
mesh_terms: D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010309:Parotitis / Q000150:complications; D012185:Retroperitoneal Fibrosis / Q000097:blood / Q000150:complications / Q000151:congenital* / Q000175:diagnosis
chemical_list: D007074:Immunoglobulin G