title: Oxidized amylose with high carboxyl content: A promising solubilizer and carrier of linalool for antimicrobial activity.
abstract: The oxidized amyloses with different carboxyl content were prepared to include linalool for antimicrobial activity in aqueous environment. The results show that linalool can be effectively reserved from volatilization through encapsulation into amylose and oxidized amyloses. The inclusion ability of oxidized amyloses towards linalool is decreasing with the increase of oxidation level due to the depolymerization of amylose. However, the solubilization effect of oxidized amyloses to linalool is enhanced efficiently owning to the high water solubility of oxidized amyloses. It is interesting that the inclusion complexes have good antimicrobial activity in aqueous environment. Linalool solubilized by oxidized amyloses presents better antimicrobial performance than that solubilized by amylose, mainly resulting from that amylose-linalool inclusion complex would aggregate and retrograde fast in aqueous solution, which is disadvantageous for the release of linalool. The study suggests that oxidized amylose is a promising solubilizer and carrier of linalool for antimicrobial activity in aqueous environment.
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
authors: Ying
authors: Y
authors: Zhou
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
authors: Youxin
authors: Y
authors: Ye
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
authors: Wenwen
authors: W
authors: Zhang
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
authors: Songling
authors: S
authors: Li
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
authors: Jing
authors: J
authors: Chen
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
authors: Shiting
authors: S
authors: Wang
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China. Electronic address: lidefu@scu.edu.cn.
authors: Defu
authors: D
authors: Li
authors: School of Chemical Engineering, Sichuan University, Chengdu 610065, China. Electronic address: cdmu@scu.edu.cn.
authors: Changdao
authors: C
authors: Mu
mesh_terms: D000080462:Acyclic Monoterpenes; D000688:Amylose / Q000008:administration & dosage* / Q000737:chemistry*; D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology; D004337:Drug Carriers / Q000008:administration & dosage / Q000737:chemistry*; D065546:Drug Liberation; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D039821:Monoterpenes / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D014961:X-Ray Diffraction
chemical_list: D000080462:Acyclic Monoterpenes; D000890:Anti-Infective Agents; D004337:Drug Carriers; D039821:Monoterpenes; D000688:Amylose; C018584:linalool
keywords: Antimicrobial activity; Inclusion complex; Linalool; Oxidized amylose; Solubilization