title: Safety and feasibility of the RhinoChill immediate transnasal evaporative cooling device during out-of-hospital cardiopulmonary resuscitation: A single-center, observational study.
abstract: We investigated feasibility and safety of the RhinoChill (RC) transnasal cooling system initiated before achieving a protected airway during cardiopulmonary resuscitation (CPR) in a prehospital setting.In out-of-hospital cardiac arrest (OHCA), transnasal evaporative cooling was initiated during CPR, before a protected airway was established and continued until either the patient was declared dead, standard institutional systemic cooling methods were implemented or cooling supply was empty. Patients were monitored throughout the hypothermia period until either death or hospital discharge. Clinical assessments and relevant adverse events (AEs) were documented over this period of time.In total 21 patients were included. Four were excluded due to user errors or meeting exclusion criteria. Finally, 17 patients (f = 6; mean age 65.5 years, CI95%: 57.7-73.4) were analyzed. Device-related AEs, like epistaxis or nose whitening, occurred in 2 patients. They were mild and had no consequence on the patient's outcome. According to the field reports of the emergency medical services (EMS) personnel, no severe technical problems occurred by using the RC device that led to a delay or the impairment of quality of the CPR.Early application of the RC device, during OHCA is feasible, safe, easy to handle, and does not delay or hinder CPR, or establishment of a secure intubation. For efficacy and further safety data additional studies will be needed.
authors: Department of Emergency Medicine, Medical University of Vienna Wiener Berufsrettung, Municipal Ambulance Service, Vienna University Hospital St. Pölten, Karl-Landsteiner Medical University, Lower Austria Department of Internal Medicine III, Divison of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
authors: Marie-Sophie
authors: MS
authors: Grave
authors: Fritz
authors: F
authors: Sterz
authors: Alexander
authors: A
authors: Nürnberger
authors: Stergios
authors: S
authors: Fykatas
authors: Mathias
authors: M
authors: Gatterbauer
authors: Albert Friedrich
authors: AF
authors: Stättermayer
authors: Andreas
authors: A
authors: Zajicek
authors: Reinhard
authors: R
authors: Malzer
authors: Dieter
authors: D
authors: Sebald
authors: Raphael
authors: R
authors: van Tulder
mesh_terms: D000368:Aged; D000552:Ambulances; D001317:Austria / Q000453:epidemiology; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced / Q000295:instrumentation* / Q000379:methods; D008297:Male; D008875:Middle Aged; D058687:Out-of-Hospital Cardiac Arrest / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D061214:Patient Safety; D011446:Prospective Studies