title: A naphthalene-based two-photon fluorescent probe for selective and sensitive detection of endogenous hypochlorous acid.
abstract: An efficient naphthalene-based two-photon fluorescent probe for endogenous HClO has been reported in the present study, which consists of a 6-(2-benzothiazolyl)-2-naphthalenol fluorophore connected with a 4-aminophenol (the fluorescence quenching and response group). This probe exhibits a high selectivity and excellent sensitivity with a detection limit of 7.6nM over other reactive oxygen species and analyte species, and the fluorescence intensity enhanced 103-fold when responsed. Furthermore, it was successfully used for two-photon imaging of endogenous HClO in live cells with high-resolution.
authors: College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China; Environment Monitoring Department, Changsha Environmental Protection College, Changsha, 410004 China.
authors: Xiao-Hong
authors: XH
authors: Zhou
authors: College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China. Electronic address: jiangyr@mail.csu.edu.cn.
authors: Yu-Ren
authors: YR
authors: Jiang
authors: College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China.
authors: Xiong-Jie
authors: XJ
authors: Zhao
authors: College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China.
authors: Dong
authors: D
authors: Guo
keywords: Hypochlorous acid; Reactive oxygen species (ROS); Two-photon fluorescent probe