title: [Alcohol and arrhythmias].
abstract: The effects of alcohol on induction of arrhythmias is dose-dependent, independent of preexisting cardiovascular diseases or heart failure and can affect otherwise healthy subjects. While the probability of atrial fibrillation increases with the alcohol dosage, events of sudden cardiac death are less frequent with low and moderate consumption but occur more often in heavy drinkers with alcoholic cardiomyopathy. Men are first affected at higher dosages of alcohol but women can suffer from arrhythmias at lower dosages. Thromboembolisms and ischemic stroke can occur less often at lower dosages of alcohol; however, hemorrhagic stroke and subarachnoid hemorrhage are increased with higher alcohol dosages. Recognizable protective mechanisms of alcohol with respect to cardiovascular diseases only occur with lower amounts of alcohol of less than 10 g per day. Underlying mechanisms explain these controversial effects. Specific therapeutic options for alcohol-related arrhythmias apart from abstinence from alcohol consumption are not known.
authors: Abt. Kardiologie & Angiologie, Department für Innere Medizin, Neurologie und Dermatologie, Universität Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland. pfeid@medizin.uni-leipzig.de.
authors: D
authors: D
authors: Pfeiffer
authors: Abt. Kardiologie & Angiologie, Department für Innere Medizin, Neurologie und Dermatologie, Universität Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland.
authors: D
authors: D
authors: Jurisch
authors: Abt. Kardiologie & Angiologie, Department für Innere Medizin, Neurologie und Dermatologie, Universität Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland.
authors: M
authors: M
authors: Neef
authors: Abt. Kardiologie & Angiologie, Department für Innere Medizin, Neurologie und Dermatologie, Universität Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland.
authors: A
authors: A
authors: Hagendorff
mesh_terms: D000428:Alcohol Drinking / Q000401:mortality*; D001145:Arrhythmias, Cardiac / Q000401:mortality*; D002310:Cardiomyopathy, Alcoholic / Q000401:mortality*; D015984:Causality; D015897:Comorbidity; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000506:poisoning*; D006801:Humans; D015994:Incidence; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D000431:Ethanol
keywords: Alcoholic cardiomyopathy; Alcoholism; Atrial fibrillation; Cardiac arrhythmias; Holiday heart syndrome