title: Endocrine active contaminants in aquatic systems and intersex in common sport fishes.
abstract: Male fish are susceptible to developing intersex, a condition characterized by the presence of testicular oocytes. In the present study, the relationship between intersex and exposure to estrogenic endocrine active contaminants (EACs) was assessed for 2 genera of sport fish, Micropterus and Lepomis, at 20 riverine sites. Seasonal trends and relationships between EACs and intersex (prevalence and severity) were examined at varying putative sources of EACs throughout North Carolina, identified as point sources, nonpoint sources, and reference sites. Intersex was identified in both genera, which was documented for the first time in wild-caught Lepomis. Intersex was more prevalent (59.8%) and more severe (1.6 mean rank) in Micropterus, which was highly correlation to EACs in sediment. In contrast, intersex was less common (9.9%) and less severe (0.2 mean rank) in Lepomis and was highly correlated to EACs in the water column. The authors found that concentrations of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, industrial EACs, and estrogens were highest at point source sites; however, no source type variation was identified in the prevalence or severity of intersex, nor were there seasonal trends in intersex or EAC concentrations. The authors' results associate genus-specific prevalence of intersex with specific EAC classes in common sport fishes having biological, ecological, and conservation implications. Environ Toxicol Chem 2017;36:959-968. © 2016 SETAC.
authors: Department of Biological Sciences, Environmental and Molecular Toxicology Program, North Carolina State University, Raleigh, North Carolina, USA.
authors: Crystal S D
authors: CS
authors: Lee Pow
authors: Department of Population Health and Pathobiology, North Carolina State University, Raleigh, North Carolina, USA.
authors: J Mac
authors: JM
authors: Law
authors: US Geological Survey, North Carolina Cooperative Fish and Wildlife Research Unit, Raleigh, North Carolina, USA.|Department of Applied Ecology, North Carolina State University, Raleigh, North Carolina, USA.
authors: Thomas J
authors: TJ
authors: Kwak
authors: Department of Applied Ecology, North Carolina State University, Raleigh, North Carolina, USA.
authors: W Gregory
authors: WG
authors: Cope
authors: Department of Applied Ecology, North Carolina State University, Raleigh, North Carolina, USA.
authors: James A
authors: JA
authors: Rice
authors: Department of Biological Sciences, Environmental and Molecular Toxicology Program, North Carolina State University, Raleigh, North Carolina, USA.
authors: Seth W
authors: SW
authors: Kullman
authors: Department of Applied Ecology, North Carolina State University, Raleigh, North Carolina, USA.
authors: D Derek
authors: DD
authors: Aday
mesh_terms: D000818:Animals; D001492:Bass / Q000254:growth & development* / Q000378:metabolism; D012734:Disorders of Sex Development / Q000139:chemically induced*; D052244:Endocrine Disruptors / Q000032:analysis* / Q000633:toxicity; D004703:Endocrine System / Q000187:drug effects*; D004784:Environmental Monitoring; D005260:Female; D008297:Male; D009657:North Carolina; D009865:Oocytes / Q000187:drug effects / Q000254:growth & development; D045483:Rivers / Q000737:chemistry*; D012621:Seasons; D013045:Species Specificity; D013177:Sports; D013737:Testis / Q000187:drug effects / Q000254:growth & development; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000633:toxicity
chemical_list: D052244:Endocrine Disruptors; D014874:Water Pollutants, Chemical
keywords: Black bass; Endocrine disruption; Estrogens; Intersex; Sunfish