title: Ambulatory monitoring of myocardial ischemia in the 21st century-an opportunity for high frequency QRS analysis.
abstract: Ambulatory monitoring represents an effective tool for the assessment of silent and transient myocardial ischemia during routine daily activities. Incidence of silent ischemia can provide important prognostic information about patients with coronary artery disease or acute coronary syndrome, as well as about post-myocardial infarction patients. The current technological progress enables development of powerful and miniaturized wearable devices for Holter monitoring. Higher sampling rates, dynamic range, and extended computational and storage capacity allow for considering of more complex methodological solutions such as high-frequency QRS analysis for diagnosing myocardial ischemia. Implementation of suitable methodologies for advanced detection of myocardial ischemia into modern ambulatory monitoring devices creates the potential of making the ambulatory myocardial ischemia monitoring a valuable diagnostic tool in clinical practice.
authors: International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; Institute of Scientific Instruments of the Czech Academy of Sciences, Czech Republic. Electronic address: pavel.leinveber@fnusa.cz.
authors: Pavel
authors: P
authors: Leinveber
authors: International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; Institute of Scientific Instruments of the Czech Academy of Sciences, Czech Republic.
authors: Josef
authors: J
authors: Halamek
authors: International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; Institute of Scientific Instruments of the Czech Academy of Sciences, Czech Republic.
authors: Pavel
authors: P
authors: Jurak
mesh_terms: D000465:Algorithms; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D015716:Electrocardiography, Ambulatory / Q000379:methods*; D000070276:Heart Rate Determination / Q000379:methods*; D006801:Humans; D017202:Myocardial Ischemia / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted
keywords: Ambulatory monitoring; HF-QRS; Holter monitoring; Myocardial Ischemia; Silent Ischemia