title: Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
abstract: Chronic kidney disease (CKD) has been used as a model and source of knowledge concerning the mechanisms, clinical relevance and accelerated progression of cardiovascular (CV) calcification, as well as its consequences in clinical practice, despite we know that it is a late secondary ossification phenomenon and only circumstantial evidence is available. In this comprehensive review, we firstly describe the types of CV calcification which affect CKD patients, and we analyse how its presence is directly associated with CV events and increased mortality in these patients. We also justify the use of CV calcification assessment in regular nephrology clinical practice, because CV calcification is an important predictor of clinical outcome in these patients. Consequently, we believe that CV calcification assessment is a tool that could and should be used by nephrologists when making a decision concerning individual patients, consistent with the current trend of an ever-more-personalised therapeutic approach.
authors: Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España. Electronic address: jbover@fundacio-puigvert.es.
authors: Jordi
authors: J
authors: Bover
authors: Servicio de Nefrología, Hospital Universitario Doctor Peset, Valencia, España.
authors: José Luis
authors: JL
authors: Górriz
authors: Departamento de Nefrología y Diálisis, Clinique du Landy, Departamento de Fisiología Renal, Hospital Necker, Universidad de París Descartes, París, Francia.
authors: Pablo
authors: P
authors: Ureña-Torres
authors: Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.
authors: María Jesús
authors: MJ
authors: Lloret
authors: Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.
authors: César
authors: C
authors: Ruiz-García
authors: Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.
authors: Iara
authors: I
authors: daSilva
authors: Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.
authors: Pamela
authors: P
authors: Chang
authors: Servicio de Nefrología, Hospital de Universitario Reina Sofía, IMIBIC, Universidad de Córdoba, Córdoba, España.
authors: Mariano
authors: M
authors: Rodríguez
authors: Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.
authors: José
authors: J
authors: Ballarín
mesh_terms: D018450:Disease Progression; D006801:Humans; D000072104:Nephrologists; D051436:Renal Insufficiency, Chronic / Q000150:complications*; D061205:Vascular Calcification / Q000175:diagnosis*
keywords: Adragao; Agatston; CKD-MBD; Calcificación vascular; Calcio; Calcium; Chronic kidney disease; Enfermedad renal crónica; Fósforo; Hiperparatiroidismo; Hyperparathyroidism; Kauppila; Metabolismo mineral; Mineral metabolism; Phosphorus; Vascular calcification