title: Xenon Difluoride Mediated Fluorodecarboxylations for the Syntheses of Di- and Trifluoromethoxyarenes.
abstract: XeF2 is demonstrated to be a more proficient fluorine-transfer reagent than either NFSI or Selectfluor in fluorodecarboxylations of both mono- and difluoroaryloxy acetic acid derivatives. This method efficiently converts a wide range of neutral and electron-poor substrates to afford the desired di- and trifluoromethyl aryl ethers in good to excellent yields. The purifications are facile, and the reaction times are less than 5 min, which makes these fluorodecarboxylations promising for future PET-imaging applications.
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Claire
authors: C
authors: Chatalova-Sazepin
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Meruyert
authors: M
authors: Binayeva
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Maxim
authors: M
authors: Epifanov
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Wei
authors: W
authors: Zhang
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Paul
authors: P
authors: Foth
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Carolyn
authors: C
authors: Amador
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Manu
authors: M
authors: Jagdeo
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Benjamin R
authors: BR
authors: Boswell
authors: Chemistry Department, University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
authors: Glenn M
authors: GM
authors: Sammis