title: A synonymous variant in TREX1 is associated with systemic sclerosis and severe digital ischaemia.
authors: a Centre for Musculoskeletal Research, The University of Manchester, Manchester Academic Health Science Centre , Manchester , UK.
authors: M
authors: M
authors: Hughes
authors: a Centre for Musculoskeletal Research, The University of Manchester, Manchester Academic Health Science Centre , Manchester , UK.
authors: J
authors: J
authors: Little
authors: a Centre for Musculoskeletal Research, The University of Manchester, Manchester Academic Health Science Centre , Manchester , UK.|b NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre , Manchester , UK.
authors: A L
authors: AL
authors: Herrick
authors: c The Wolfson Centre for Personalised Medicine, Department of Molecular and Clinical Pharmacology , University of Liverpool , Liverpool , UK.
authors: S
authors: S
authors: Pushpakom
authors: d Manchester Centre for Genomic Medicine , Central Manchester University Hospitals NHS Foundation Trust and University of Manchester , Manchester , UK.
authors: H
authors: H
authors: Byers
authors: a Centre for Musculoskeletal Research, The University of Manchester, Manchester Academic Health Science Centre , Manchester , UK.|b NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre , Manchester , UK.
authors: J
authors: J
authors: Worthington
authors: d Manchester Centre for Genomic Medicine , Central Manchester University Hospitals NHS Foundation Trust and University of Manchester , Manchester , UK.
authors: W G
authors: WG
authors: Newman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005090:Exodeoxyribonucleases / Q000235:genetics*; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000209:etiology*; D008875:Middle Aged; D010750:Phosphoproteins / Q000235:genetics*; D045745:Scleroderma, Limited / Q000150:complications / Q000235:genetics*; D014034:Toes / Q000098:blood supply*; D055815:Young Adult
chemical_list: D010750:Phosphoproteins; D005090:Exodeoxyribonucleases; C429526:three prime repair exonuclease 1