title: Pleiotropic Analysis of Lung Cancer and Blood Triglycerides.
abstract: Epidemiologically related traits may share genetic risk factors, and pleiotropic analysis could identify individual loci associated with these traits. Because of their shared epidemiological associations, we conducted pleiotropic analysis of genome-wide association studies of lung cancer (12 160 lung cancer case patients and 16 838 control subjects) and cardiovascular disease risk factors (blood lipids from 188 577 subjects, type 2 diabetes from 148 821 subjects, body mass index from 123 865 subjects, and smoking phenotypes from 74 053 subjects). We found that 6p22.1 (rs6904596, ZNF184) was associated with both lung cancer (P = 5.50x10(-6)) and blood triglycerides (P = 1.39x10(-5)). We replicated the association in 6097 lung cancer case patients and 204 657 control subjects (P = 2.40 × 10(-4)) and in 71 113 subjects with triglycerides data (P = .01). rs6904596 reached genome-wide significance in lung cancer meta-analysis (odds ratio = 1.15, 95% confidence interval = 1.10 to 1.21 ,: Pcombined = 5.20x10(-9)). The large sample size provided by the lipid GWAS data and the shared genetic risk factors between the two traits contributed to the uncovering of a hitherto unidentified genetic locus for lung cancer.
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Verena
authors: V
authors: Zuber
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Crystal N
authors: CN
authors: Marconett
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Jianxin
authors: J
authors: Shi
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Xing
authors: X
authors: Hua
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: William
authors: W
authors: Wheeler
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Chenchen
authors: C
authors: Yang
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Lei
authors: L
authors: Song
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Anders M
authors: AM
authors: Dale
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Marina
authors: M
authors: Laplana
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Angela
authors: A
authors: Risch
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Aree
authors: A
authors: Witoelar
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Wesley K
authors: WK
authors: Thompson
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Andrew J
authors: AJ
authors: Schork
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Francesco
authors: F
authors: Bettella
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Yunpeng
authors: Y
authors: Wang
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Srdjan
authors: S
authors: Djurovic
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Beiyun
authors: B
authors: Zhou
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Zea
authors: Z
authors: Borok
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Henricus F M
authors: HF
authors: van der Heijden
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Jacqueline
authors: J
authors: de Graaf
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Dorine
authors: D
authors: Swinkels
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Katja K
authors: KK
authors: Aben
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: James
authors: J
authors: McKay
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Rayjean J
authors: RJ
authors: Hung
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Heike
authors: H
authors: Bikeböller
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Victoria L
authors: VL
authors: Stevens
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Demetrius
authors: D
authors: Albanes
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Neil E
authors: NE
authors: Caporaso
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Younghun
authors: Y
authors: Han
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Yongyue
authors: Y
authors: Wei
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Maria Angeles
authors: MA
authors: Panadero
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Jose I
authors: JI
authors: Mayordomo
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: David C
authors: DC
authors: Christiani
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Lambertus
authors: L
authors: Kiemeney
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Ole A
authors: OA
authors: Andreassen
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Richard
authors: R
authors: Houlston
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Christopher I
authors: CI
authors: Amos
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Nilanjan
authors: N
authors: Chatterjee
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Ite A
authors: IA
authors: Laird-Offringa
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Ian G
authors: IG
authors: Mills
authors: NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine (VZ, AW, FB, YW, OAA), and Prostate Cancer Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership (VZ, IGM), University of Oslo, Oslo, Norway; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway (VZ, AW, FB, YW, OAA); European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK (VZ); Departments of Surgery and of Biochemistry and Molecular Biology (CNM, CY, IALO) and Will Rogers Institute Pulmonary Research Center and Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (BZ, ZB), Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (CNM, CY, IALO); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Public Health Service, Bethesda, MD (JS, XH, LS, DA, NEC, NC, MTL); Information Management Services, Inc.; Rockville, MD (WW); Multimodal Imaging Laboratory (AMD, AJS), Center for Human Development (AMD, AJS), Department of Radiology (AMD), Department of Neurosciences (AMD), Department of Psychiatry (WKT), and Cognitive Sciences Graduate Program (AJS), University of California, San Diego, La Jolla, CA; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany (ML, AR); Department of Molecular Biology, University of Salzburg, Salzburg, Austria (AR); Translational Lung Research Center Heidelberg TLRC-H, Member of the German Center for Lung Research DZL, Heidelberg, Germany (AR); Department of Medical Genetics (SD) and Department of Molecular Oncology, Institute of Cancer Research and Department of Urology (IGM), Oslo University Hospital, Oslo, Norway (SD); NORMENT, KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway (SD); Radboud Unive
authors: Maria Teresa
authors: MT
authors: Landi
mesh_terms: D002318:Cardiovascular Diseases / Q000453:epidemiology; D016022:Case-Control Studies; D002896:Chromosomes, Human, Pair 6; D058685:Genetic Pleiotropy; D055106:Genome-Wide Association Study; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000453:epidemiology* / Q000235:genetics*; D015201:Meta-Analysis as Topic; D020641:Polymorphism, Single Nucleotide; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood* / Q000235:genetics*
chemical_list: D014280:Triglycerides