title: The Relationship between Corvis ST Tonometry and Ocular Response Analyzer Measurements in Eyes with Glaucoma.
abstract: It is important to compare the results of Corneal Visualization Scheimpflug Technology instrument (CST) measurements and Reichert Ocular Response Analyzer (ORA) parameters. The purpose of the study was to investigate the association between CST measurements and ORA parameters in ninety-five patients with primary open-angle glaucoma. Measurements of CST, ORA, axial length (AL), average corneal curvature (CC), central corneal thickness (CCT) and intraocular pressure (IOP) with Goldmann applanation tonometry (GAT) were carried out. The association between CST and ORA parameters was assessed using linear regression analysis, with model selection based on the second order bias corrected Akaike Information Criterion index. Measurements from ORA (corneal hysteresis [CH] and corneal response factor [CRF]) had high intraclass correlation coefficients (ICC) and low coefficients of variation, but some CST parameters showed much lower reproducibility, namely: A1 length, A2 length, highest concavity time and peak distance. Of 12 CST parameters tested, 8 were significantly correlated with CH and 10 were significantly correlated with CRF, however, the magnitude of the correlation coefficients were weak to moderate at best. The optimal model to explain CH using CST measurements was given by: CH = -76.3 + 4.6*A1 time + 1.9*A2 time + 3.1 * highest concavity deformation amplitude + 0.016*CCT (R2 = 0.67, p <0.001). Similarly, the optimal model for CRF was given by: CRF = -53.5 + 4.2*A1 time + 1.9*A1 length + 20.8*A1 deformation amplitude + 0.8*A2 time + 0.017*CCT (R2 = 0.73, p <0.001). ORA parameters show higher reproducibility than CST measurements. Although many CST parameters are significantly related to ORA parameters, the strengths of these relationships are weak to moderate.
authors: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors: Masato
authors: M
authors: Matsuura
authors: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.|Orthoptics and Visual Science, Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan.
authors: Kazunori
authors: K
authors: Hirasawa
authors: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors: Hiroshi
authors: H
authors: Murata
authors: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors: Mieko
authors: M
authors: Yanagisawa
authors: Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima, Japan.
authors: Yoshitaka
authors: Y
authors: Nakao
authors: Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan.
authors: Shunsuke
authors: S
authors: Nakakura
authors: Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima, Japan.
authors: Yoshiaki
authors: Y
authors: Kiuchi
authors: Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
authors: Ryo
authors: R
authors: Asaoka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005123:Eye / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D014065:Tonometry, Ocular