title: Comparative efficacy of BioRelease Deslorelin® injection for induction of ovulation in oestrus mares: a field study.
abstract: OBJECTIVE
  To investigate the comparative efficacy of BioRelease Deslorelin® (BRD) and Ovuplant® for induction of ovulation in cyclic mares in Australia.
  
  
  METHODS
  Ovarian follicular activity of 60 mares for a total of 95 cycles was monitored by ultrasonography until they developed a follicle ≥30 mm and a uterine oedema pattern of 3. Mares were then randomly allocated to one of three treatment groups: (1) treatment with 1.25 mg BRD, (2) a single Ovuplant pellet or (3) 1 mL compound sodium lactate control. Follicular activity was monitored with ultrasonography every 12 h until ovulation was detected or for at least 5 days post treatment. The injection site on each mare was monitored for reaction for a minimum of 5 days post treatment.
  
  
  RESULTS
  There was no difference in the percentage of mares ovulating within 48 h when treated with BRD (93.75%) compared with Ovuplant (87.09%). Treatment with both ovulating agents significantly decreased the time to ovulation compared with control mares (P < 0.00005). More mares had injection site reactions with Ovuplant (64.5%) treatment compared with BRD (15.6%) or control mares (0%) (P < 0.00005).
  
  
  CONCLUSIONS
  Treatment of mares with 1.25 mg BRD when there is a follicle ≥30 mm and uterine oedema pattern of 3 is as effective as treatment with Ovuplant.
authors: Goulburn Valley Equine Hospital, Congupna 3633, Victoria, Australia. sfinan@gmail.com.
authors: S A
authors: SA
authors: Finan
authors: Caledonian Holdings, Ascot Vale, VIC, Australia.
authors: E L
authors: EL
authors: Lamkin
authors: Goulburn Valley Equine Hospital, Congupna 3633, Victoria, Australia.
authors: A O
authors: AO
authors: McKinnon
mesh_terms: D000818:Animals; D004343:Drug Implants; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects; D005260:Female; D006736:Horses / Q000502:physiology*; D007273:Injections, Intramuscular / Q000662:veterinary; D016014:Linear Models; D010060:Ovulation / Q000187:drug effects*; D010062:Ovulation Induction / Q000379:methods / Q000662:veterinary*; D017329:Triptorelin Pamoate / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D014463:Ultrasonography / Q000662:veterinary
chemical_list: D004343:Drug Implants; D004791:Enzyme Inhibitors; D017329:Triptorelin Pamoate; C066438:deslorelin
keywords: breeding programs; horses; oestrus; ovulation agents