title: A meta-analysis of sperm donation offspring health outcomes.
abstract: Although the use of donor sperm as a treatment modality for male infertility has become common place, the health outcomes for those conceived has been poorly studied. A structured search of the literature using PubMed, EMBASE and Cochrane Reviews was performed to investigate the health outcomes of offspring conceived from donor sperm. Eight studies were eligible and included in the review, and of these, three were included in a meta-analysis. Meta-analysis of clinical outcomes showed that donor sperm neonates are not at increased risk of being born of low birth weight (<2500 g), preterm (<37 weeks) or with increased incidences of birth defects, than spontaneously conceived neonates.
authors: 1School of Nursing and Midwifery,Flinders University,Bedford Park,SA,Australia.
authors: D H
authors: DH
authors: Adams
authors: 1School of Nursing and Midwifery,Flinders University,Bedford Park,SA,Australia.
authors: R A
authors: RA
authors: Clark
authors: 2Robinson Institute,The University of Adelaide,Adelaide,SA,Australia.
authors: M J
authors: MJ
authors: Davies
authors: 1School of Nursing and Midwifery,Flinders University,Bedford Park,SA,Australia.
authors: S
authors: S
authors: de Lacey
mesh_terms: D000013:Congenital Abnormalities / Q000453:epidemiology*; D005260:Female; D005307:Fertilization in Vitro; D006304:Health Status; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D047928:Premature Birth; D015995:Prevalence; D013094:Spermatozoa; D014019:Tissue Donors
keywords: Donor conception; meta-analysis; neonate; outcome; sperm