title: Microgravity directs stem cell differentiation.
abstract: Stem cells are the cell of origin for organisms and their organs. These cells are critical for tissue regeneration, as well as regenerative medicine. Mechanical forces, such as gravity, have been demonstrated to provide important signals for stem cell fate. In fact, the absence of gravity, that is, microgravity, affects almost all aspects of human physiology, which has been partly attributed to changes in the biological behaviors of stem cells. In this review, we summarize the current understanding of the effects of microgravity on stem cell differentiation that control the fate of stem cells.
authors: Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China.
authors: Zhe
authors: Z
authors: Chen
authors: Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China.
authors: Qing
authors: Q
authors: Luo
authors: Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China.|National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing, China.
authors: Lin
authors: L
authors: Yuan
authors: Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China. song@cqu.edu.cn.
authors: Guanbin
authors: G
authors: Song
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D006801:Humans; D013234:Stem Cells / Q000166:cytology*; D014893:Weightlessness