title: Does Nature Know Best? Pericyclic Reactions in the Daphniphyllum Alkaloid-Forming Cation Cascade.
abstract: Heathcock's classic cyclization/rearrangement cascade for formation of Daphniphyllum alkaloids is subjected to analysis using density functional theory calculations. The results of these calculations are consistent with a two-step pathway involving two pericyclic reactions, a Diels-Alder cycloaddition and an ene reaction.
authors: Department of Chemistry, University of California-Davis , Davis, California 95616, United States.
authors: Dean J
authors: DJ
authors: Tantillo