title: Relationship between18FDG-PET and different types of sinonasal malignancies.
abstract: CONCLUSIONS
  The sensitivity and specificity of a18FDG-PET scan may be different according to the histology. The SUVmaxand SUV ratio may reflect the tumor's aggressive behavior.
  
  
  OBJECTIVE
  To describe the characteristics of PET/CT scans, including the maximum standard uptake values (SUVmax), at initial diagnosis according to six main types of sinonasal malignancies: sinonasal adenocarcinoma (SNAC), sinonasal undifferentiated carcinoma (SNUC), adenoid cystic carcinoma (ACC), sinonasal malignant melanoma (SMM), olfactory neuroblastoma (ONB), and sinonasal neuroendocrine carcinoma (SNEC).
  
  
  METHODS
  A chart review of 50 patients who were diagnosed and treated for six sinonasal malignancy types over a period of 6 years was conducted. Any18F-FDG PET/CT scans for each patient were searched using the hospital's intranet. The SUVmaxof the primary sinonasal site was recorded. The liver SUVs were utilized as reference SUVs. The SUV ratio was defined as the ratio of the SUVmaxof the primary tumor and the SUVliver.
  
  
  RESULTS
  The most common malignancy was SNAC (32%), followed by SNUC (24%), ONB (14%), ACC (10%), SMM (10%), and SNEC (10%). The SUVmaxand SUV ratio values were significantly different between tumor types (p = 0.002 and 0.012, respectively). SNUC had the highest mean SUVmax(14.2), followed by SNAC (9.9). A similar mean SUVmaxwas observed for SMM, ONB, and ACC (∼ 7.0). SNEC up-takes the least18FDG among these six tumor types (mean SUVmax= 4.7).
authors: a Department of Otorhinolaryngology - Head and Neck Surgery , University Hospital of Nancy , Nancy , France.
authors: Marylisa
authors: M
authors: Felix-Ravelo
authors: a Department of Otorhinolaryngology - Head and Neck Surgery , University Hospital of Nancy , Nancy , France.
authors: Ayoub
authors: A
authors: Bey
authors: b Faculty of Medicine , University of Lorraine , France.
authors: Fabien
authors: F
authors: Arous
authors: c Department of Nuclear Medicine , University Hospital of Nancy , Nancy , France.
authors: Solène
authors: S
authors: Paris-Grandpierre
authors: a Department of Otorhinolaryngology - Head and Neck Surgery , University Hospital of Nancy , Nancy , France.|b Faculty of Medicine , University of Lorraine , France.
authors: Roger
authors: R
authors: Jankowski
authors: a Department of Otorhinolaryngology - Head and Neck Surgery , University Hospital of Nancy , Nancy , France.
authors: Duc Trung
authors: DT
authors: Nguyen
mesh_terms: D000368:Aged; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging*; D000072078:Positron Emission Tomography Computed Tomography; D012189:Retrospective Studies
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: PET/CT scans; adenoid cystic carcinoma; olfactory neuroblastoma; sinonasal adenocarcinoma; sinonasal malignancy; sinonasal malignant melanoma; sinonasal neuroendocrine carcinoma; sinonasal undifferentiated carcinoma; standard uptake value