title: Amyloïdosis, sarcoidosis and systemic lupus erythematosus.
abstract: The occurrence of renal and multiple organ Amyloïdosis is currently considered exceptional in the course of systemic lupus erythematosus. We report a case of a concomitant SLE and Amyloïdosis in a 57 year old female patient with hypothyroidism history, who presented with erythema nodosum, fever, arthralgia and sicca syndrome. Biological findings showed an inflammatory syndrome, renal failure, proteinuria (1g / 24h), positive auto antibodies and anti DNA. Lung radiology revealed medistinal lymphadenopathy, pleural nodules, ground glass infiltrates and pleuritis. Bronchial biopsy showed non specific inflammation. The salivary gland biopsy showed amyloïd deposits. This case report reminds us that lupus and Amyloïdosis association, although exceptional remains possible. The occurrence of Lofgren syndrome in this situation make the originality of this report.
authors: Internal Medicine Department, CHU Sahloul, Tunisia.
authors: Amel
authors: A
authors: Rezgui
authors: Internal Medicine Department, CHU Sahloul, Tunisia.
authors: Imene Ben
authors: IB
authors: Hassine
authors: Internal Medicine Department, CHU Sahloul, Tunisia.
authors: Monia
authors: M
authors: Karmani
authors: Internal Medicine Department, CHU Sahloul, Tunisia.
authors: Fatma Ben
authors: FB
authors: Fredj
authors: Internal Medicine Department, CHU Sahloul, Tunisia.
authors: Chadia
authors: C
authors: Laouani
mesh_terms: D000686:Amyloidosis / Q000209:etiology* / Q000503:physiopathology; D001323:Autoantibodies / Q000276:immunology; D001706:Biopsy; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000473:pathology; D008168:Lung / Q000000981:diagnostic imaging / Q000503:physiopathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D011507:Proteinuria / Q000175:diagnosis; D051437:Renal Insufficiency / Q000209:etiology*; D012469:Salivary Glands / Q000473:pathology; D012507:Sarcoidosis / Q000209:etiology* / Q000503:physiopathology; D013577:Syndrome
chemical_list: D001323:Autoantibodies
keywords: Amyloïdosis; lupus erythematosus; sarcoïdosis