title: Successful Management of Intraoperative Acute Bilateral Pulmonary Embolism in a High Grade Astrocytoma Patient.
abstract: BACKGROUND Intraoperative pulmonary embolism (PE) is a rare life-threatening complication in patients undergoing surgical intervention. Generally, cancer patients have a higher risk for developing this complication. Unfortunately, there is no standard procedure for its management. CASE REPORT We report the case of a 39-year-old woman with high-grade glioma in the right frontal lobe who was admitted to the surgical theater for craniotomy and excision of the tumor. During the general anesthesia procedure and just before inserting the central venous line, her end-tidal CO2 and O2 saturation dropped sharply. The anesthesiologist quickly responded with an aggressive resuscitation procedure that included aspiration through the central venous line, 100% O2, and IV administration of ephedrine 6 mg, colloid 500 mL, normal saline 500 mL, and heparin 5000 IU. The patient was extubated and remained in the supine position until she regained consciousness and her vital signs returned to normal. Subsequent radiological examination revealed a massive bilateral PE. A retrievable inferior vena cava (IVC) filter was inserted, and enoxaparin anticoagulant therapy was prescribed to stabilize the patient's condition. After 3 weeks, she underwent an uneventful craniotomy procedure and was discharged a week later under the enoxaparin therapy. CONCLUSIONS The successful management of intraoperative PE requires a quick, accurate diagnosis accompanied with an aggressive, fast response. Anesthesiologists are usually the ones who are held accountable for the diagnosis and early management of this complication. They must be aware of the possibility of such a complication and be ready to react properly and decisively in the operation theater.
authors: Department of Anesthesiology, Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan.
authors: Wail N
authors: WN
authors: Khraise
authors: Department of Anatomy, Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan.
authors: Mohammed Z
authors: MZ
authors: Allouh
authors: Division of Neurosurgery, Department of Neuroscience, Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan.
authors: Mohammad Y
authors: MY
authors: Hiasat
authors: Department of Anatomy, Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan.
authors: Raed S
authors: RS
authors: Said
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D001254:Astrocytoma / Q000601:surgery*; D001932:Brain Neoplasms / Q000601:surgery*; D017984:Enoxaparin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000628:therapy*; D016306:Vena Cava Filters
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin