title: Perioperative factors associated with short- and long-term outcomes after tricuspid valve replacement.
abstract: Appropriate patient selection for tricuspid valve replacement (TVR) is crucial for optimal outcomes, but the objective criteria for clinical decision-making remain poorly defined. This study aimed to investigate the factors associated with short- and long-term survival and morbidity.
  
  
  
  This was a retrospective study of 202 consecutive patients who underwent TVR at the Beijing Anzhen Hospital over a 21-year period (from November 1993 to March 2014). Data were extracted from the hospital's computerized database with additional information obtained through mail or telephone interview.
  
  
  
  The overall 30-day mortality was 16%. Multivariate analysis showed that the dose of frusemide [odds ratio (OR) = 1.021, 95% confidence interval (95% CI): 1.003-1.038; P = 0.018] was an independent predictor of short-term death after TVR. The dose of frusemide (OR = 1.024, 95% CI: 1.008-1.040; P = 0.002), previous operation (OR = 4.681, 95% CI: 1.938-11.310; P = 0.01) and cardiopulmonary bypass time (OR = 1.013, 95% CI: 1.007-1.020; P < 0.001) were independently associated with the low output syndrome (LOS). After 8.2 ± 5.6 (range 1-22) years of follow-up, the survival rates were 75 ± 3, 71 ± 4 and 63 ± 5% at 5, 10 and 15 years, respectively. Preoperative hypoproteinaemia and postoperative LOS were independently associated with long-term mortality.
  
  
  
  This study identified a number of factors that were independently associated with short-term mortality, short-term LOS and long-term mortality of patients after TVR.
authors: Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing, China.
authors: Bin
authors: B
authors: Mao
authors: Department of Cardiovascular Surgery, Beijing Aortic Disease Center, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing, China lizhongsun@foxmail.com.
authors: Lizhong
authors: L
authors: Sun
authors: Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing, China.
authors: Jianqun
authors: J
authors: Zhang
authors: Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing, China.
authors: Mingyang
authors: M
authors: Zhou
authors: Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing, China.
authors: Fuen
authors: F
authors: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D018579:Patient Selection; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome; D014262:Tricuspid Valve Insufficiency / Q000209:etiology / Q000401:mortality / Q000601:surgery*
keywords: Correlation analyses; Outcome; Perioperative factors; Tricuspid valve replacement