title: Platelet corrected count increments by apheresis platform.
abstract: BACKGROUND
  Automated blood collection platforms use different technological systems to isolate and collect individual blood components. These unique systems could potentially result in differences in platelet in vivo viability, as measured by the corrected count increment (CCI).
  
  
  METHODS
  This retrospective study evaluated CCI data of platelet transfusions among oncology patients who received multiple unmanipulated apheresis platelets between January 1, 2006 and December 31, 2009. Apheresis platelets were collected from our community blood center by standard procedures using two different collection systems and were transfused to patients in a blinded manner.
  
  
  RESULTS
  The CCI of the platelet recipient was significantly higher at 0-2 hours post-transfusion among the individuals who received platelets collected on Trima Accel (Terumo BCT) (mean = 6281, standard deviation = 3650) compared to the platelets collected by the Amicus system (Fresenius Kabi) (mean = 5251, standard deviation = 3311, p = 0.004).
  
  
  CONCLUSIONS
  These hypothesis-generating data suggesting improved recovery and survival of Trima Accel platelets demonstrate the need for the investigation and implementation of the best collection methods to provide better platelet transfusion support.
authors: Department of Pathology, Johns Hopkins University, Baltimore, Maryland. atobian1@jhmi.edu.
authors: Aaron A R
authors: AA
authors: Tobian
authors: Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
authors: Karen E
authors: KE
authors: King
authors: Amercian Red Cross, Rockville, Maryland.
authors: Prabhakar D
authors: PD
authors: Borge
authors: Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
authors: Alice K
authors: AK
authors: Fuller
authors: Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
authors: Kristin
authors: K
authors: Uglik
authors: Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
authors: Paul M
authors: PM
authors: Ness
mesh_terms: D001331:Automation; D001792:Blood Platelets / Q000166:cytology*; D002470:Cell Survival; D006801:Humans; D010976:Platelet Count / Q000379:methods; D017713:Platelet Transfusion / Q000379:methods / Q000592:standards; D010983:Plateletpheresis / Q000295:instrumentation* / Q000379:methods / Q000592:standards; D012189:Retrospective Studies