title: Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a case report with FDG-PET findings and literature review.
abstract: We report the 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) findings of sclerosing angiomatoid nodular transformation (SANT) of the spleen. The patient was a 37-year-old woman with a splenic mass incidentally found on abdominal ultrasound. FDG-PET/CT showed weak FDG accumulation (maximum standardized uptake value = 3.65). An unenhanced CT scan showed a low density and well-circumscribed splenic tumor that demonstrated weak enhancement from the arterial to delayed phase. Although hemangioma or hamartoma of the spleen was preoperatively diagnosed, histopathological examination revealed SANT. Therefore, when a splenic tumor with weak contrast medium enhancement and low FDG accumulation is observed, SANT should be considered as a differential diagnosis. Although CT and magnetic resonance imaging features of SANT have been reported, there are few reports on FDG-PET/CT findings. We report the radiological features of SANT, including FDG-PET/CT, and review the literature on SANT.
authors: Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
authors: Yumi
authors: Y
authors: Imamura
authors: Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
authors: Reiko
authors: R
authors: Nakajima
authors: Department of Surgery II, Tokyo Women's Medical University, Tokyo, Japan.
authors: Kazuha
authors: K
authors: Hatta
authors: Department of Surgery II, Tokyo Women's Medical University, Tokyo, Japan.
authors: Akiyoshi
authors: A
authors: Seshimo
authors: Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan.
authors: Tatsuo
authors: T
authors: Sawada
authors: Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
authors: Koichiro
authors: K
authors: Abe
authors: Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
authors: Shuji
authors: S
authors: Sakai
keywords: 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET); Sclerosing angiomatoid nodular transformation (SANT); computed tomography (CT); spleen