title: Health-Related Quality of Life and Psychological Distress in Patients With Early-Stage Hepatocellular Carcinoma After Hepatic Resection or Transplantation.
abstract: BACKGROUND
  The aim of our study was to compare the post-operative health-related quality of life in patients with small hepatocellular carcinoma (HCC; within the Milan criteria) after liver resection or liver transplantation.
  
  
  METHODS
  From August 2000 to December 2010, 207 patients were diagnosed with early HCC within the Milan criteria. We divided these patients into 2 groups according to their curative schedule: the liver transplantation group (n = 95) and the liver resection group (n = 110). We compared the baseline characteristics of these 2 groups of patients, after which we focused on comparing the post-operative health-related quality of life (HRQOL) and psychological outcome in these 2 groups.
  
  
  RESULTS
  The demographics of the patients in the 2 groups were similar, and there were no significant differences except for higher family income in the transplantation group (P = .002).With long-term follow-up, there were no significant differences in the 8 domains of the HRQOL and the 9 domains of the psychological outcome measure between the 2 groups. Both the transplantation and resection groups exhibited good outcomes in both HRQOL and psychological outcome measures.
  
  
  CONCLUSIONS
  Several years after operation, early-stage HCC patients who underwent liver transplantation or resection had similar long-term HRQOL and psychological outcomes.
authors: Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University, Chengdu, China; Liver Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors: J Y
authors: JY
authors: Lei
authors: Liver Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors: L N
authors: LN
authors: Yan
authors: Liver Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors: W T
authors: WT
authors: Wang
authors: Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University, Chengdu, China.
authors: J Q
authors: JQ
authors: Zhu
authors: The Medical Department, West China Hospital of Sichuan University, Chengdu, China. Electronic address: ldjdoctor11@163.com.
authors: D J
authors: DJ
authors: Li
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000523:psychology / Q000601:surgery*; D005260:Female; D006498:Hepatectomy / Q000523:psychology*; D006801:Humans; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000523:psychology / Q000601:surgery*; D016031:Liver Transplantation / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D013315:Stress, Psychological / Q000523:psychology; D016896:Treatment Outcome