title: Mechanical comparison of iliosacral reconstruction techniques after sarcoma resection.
abstract: Reconstruction of iliosacral defects following oncologic resection is a difficult clinical problem associated with a high incidence of failure. Technical approaches to this problem are heterogeneous and evidence supporting specific techniques is sparse. Maximizing construct stability may improve union rates and functional outcomes. The purpose of this study is to compare construct stiffness, load to failure, and mechanism of failure between two methods of iliosacral reconstruction in an ex-vivo model to determine if either is mechanically superior.
  
  
  
  Eight third-generation composite pelves reconstructed with a plate-and-screw technique were tested against seven pelves reconstructed with a minimal spinal instrumentation technique using axial loading in a double-leg stance model.
  
  
  
  The pelves from the plate group demonstrated higher stiffness in the direction of applied load (102.9 vs. 66.8N/mm; p=0.010) and endured a significantly larger maximum force (1416 vs. 1059N; p=0.015) than the rod group prior to failure. Subjectively, the rod-reconstructed pelves were noted to be rotationally unconstrained while pivoting around their single point-of fixation in each segment leading to earlier failure.
  
  
  
  Plate-reconstruction was mechanically superior to spinal instrumentation in the manner performed in this study. More than one point of fixation in each segment should be achieved to minimize the risk of rotational deformation.
authors: Washington University School of Medicine, Department of Orthopaedic Surgery, Campus Box 8233, 660 S. Euclid Ave, St. Louis, MO 63110, USA. Electronic address: louerc@wudosis.wustl.edu.
authors: Craig R
authors: CR
authors: Louer
authors: Newport Orthopedic Institute, 22 Corporate Plaza Drive, Newport Beach, CA 92660, USA; Hoag Orthopedic Institute, 16250 Sand Canyon Ave, Irvine, CA 92618, USA. Electronic address: nnassif@newportortho.com.
authors: Nader A
authors: NA
authors: Nassif
authors: Washington University School of Medicine, Department of Orthopaedic Surgery, Campus Box 8233, 660 S. Euclid Ave, St. Louis, MO 63110, USA. Electronic address: brodtm@wudosis.wustl.edu.
authors: Michael D
authors: MD
authors: Brodt
authors: Washington University School of Medicine, Department of Orthopaedic Surgery, Campus Box 8233, 660 S. Euclid Ave, St. Louis, MO 63110, USA. Electronic address: leibd@wudosis.wustl.edu.
authors: Daniel J
authors: DJ
authors: Leib
authors: Washington University School of Medicine, Department of Orthopaedic Surgery, Campus Box 8233, 660 S. Euclid Ave, St. Louis, MO 63110, USA. Electronic address: silvam@wudosis.wustl.edu.
authors: Matthew J
authors: MJ
authors: Silva
authors: Washington University School of Medicine, Department of Orthopaedic Surgery, Campus Box 8233, 660 S. Euclid Ave, St. Louis, MO 63110, USA. Electronic address: mcdonaldd@wudosis.wustl.edu.
authors: Douglas J
authors: DJ
authors: McDonald
mesh_terms: D001696:Biomechanical Phenomena; D001859:Bone Neoplasms / Q000601:surgery*; D001860:Bone Plates; D001863:Bone Screws; D004867:Equipment Design; D006622:Hip Prosthesis; D006801:Humans; D007085:Ilium / Q000601:surgery; D010388:Pelvis / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012509:Sarcoma / Q000601:surgery*; D013314:Stress, Mechanical
keywords: Iliosacral reconstruction; Mechanics; Oncology; Pelvis; Sarcoma; Spinal instrumentation