title: A new hetero dimeric terpenoid derivative, japonicaside C, from the flower buds of Lonicera japonica.
abstract: A rare hetero dimeric terpenoid derivative, named japonicaside C, together with five known secoiridoid gloucosides were isolated from the flower buds of Lonicera japonica. The structures of these compounds were established on the basis of spectroscopic analyses. Japonicaside C is the first representative of a novel type of hetero dimeric terpenoid, biogenetically originated from a guaiane-type sesquiterpenoid and a secoiridoid glucoside. Anti-virus activity of the isolated compounds was evaluated in vitro.
authors: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , P.R. China.|c State Key Lab of New-Tech for Chinese Medicine Pharmaceutical Process , Lianyungang , P.R. China.
authors: Hai-Bo
authors: HB
authors: Li
authors: b Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy , Jinan University , Guangzhou , P.R. China.
authors: Yang
authors: Y
authors: Yu
authors: b Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy , Jinan University , Guangzhou , P.R. China.
authors: Yu-Dan
authors: YD
authors: Mei
authors: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , P.R. China.|c State Key Lab of New-Tech for Chinese Medicine Pharmaceutical Process , Lianyungang , P.R. China.
authors: Zhao-Qing
authors: ZQ
authors: Meng
authors: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , P.R. China.|c State Key Lab of New-Tech for Chinese Medicine Pharmaceutical Process , Lianyungang , P.R. China.
authors: Zhen-Zhong
authors: ZZ
authors: Wang
authors: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , P.R. China.|c State Key Lab of New-Tech for Chinese Medicine Pharmaceutical Process , Lianyungang , P.R. China.
authors: Wen-Zhe
authors: WZ
authors: Huang
authors: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , P.R. China.|c State Key Lab of New-Tech for Chinese Medicine Pharmaceutical Process , Lianyungang , P.R. China.
authors: Wei
authors: W
authors: Xiao
authors: b Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy , Jinan University , Guangzhou , P.R. China.
authors: Xin-Sheng
authors: XS
authors: Yao
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D035264:Flowers / Q000737:chemistry*; D031239:Lonicera / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry; D018113:Respiratory Syncytial Virus, Human / Q000187:drug effects; D021241:Spectrometry, Mass, Electrospray Ionization; D013729:Terpenes / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D010936:Plant Extracts; D013729:Terpenes; C000617915:japonicaside C
keywords: Anti-virus; Lonicera japonica; RSV; japonicaside C; secoiridoid glucoside; sesquiterpenoid