title: ZnO-nanorods/graphene heterostructure: a direct electron transfer glucose biosensor.
abstract: ZnO-nanorods/graphene heterostructure was synthesized by hydrothermal growth of ZnO nanorods on chemically reduced graphene (CRG) film. The hybrid structure was demonstrated as a biosensor, where direct electron transfer between glucose oxidase (GOD) and electrode was observed. The charge transfer was attributed to the ZnO nanorod wiring between the redox center of GOD and electrode, and the ZnO/graphene heterostructure facilitated the transport of electrons on the hybride electrode. The glucose sensor based on the GOD-ZnO/CRG/Pt electrode had a high sensitivity of 17.64 μA mM(-1), which is higher than most of the previously reported values for direct electron transfer based glucose biosensors. Moreover, this biosensor is linearly proportional to the concentration of glucose in the range of 0.2-1.6 mM. The study revealed that the band structure of electrode could affect the detection of direct electron transfer of GOD, which would be helpful for the design of the biosensor electrodes in the future.
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Yu
authors: Y
authors: Zhao
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Wenbo
authors: W
authors: Li
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Lijia
authors: L
authors: Pan
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Dongyuan
authors: D
authors: Zhai
authors: School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors: Yu
authors: Y
authors: Wang
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Lanlan
authors: L
authors: Li
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Wen
authors: W
authors: Cheng
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Wei
authors: W
authors: Yin
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Xinran
authors: X
authors: Wang
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.|Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
authors: Jian-Bin
authors: JB
authors: Xu
authors: School of Electronic Science and Engineering, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
authors: Yi
authors: Y
authors: Shi
mesh_terms: D015374:Biosensing Techniques; D003217:Conductometry; D004566:Electrodes; D004800:Enzymes, Immobilized / Q000737:chemistry; D005947:Glucose / Q000302:isolation & purification*; D005949:Glucose Oxidase / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D006801:Humans; D043942:Nanotubes / Q000737:chemistry*; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: D004800:Enzymes, Immobilized; D006046:Gold; D006108:Graphite; D005949:Glucose Oxidase; D005947:Glucose; D015034:Zinc Oxide