title: Hemi-meningitis with hemophagocytic lymphohistiocytosis.
abstract: Hemophagocytic lymphohistiocytosis (HLH) is a rare lymphoproliferative disorder. HLH may occur as a complication of Epstein-Barr virus (EBV), particularly in patients with immunodeficiencies. Herein, we describe a 16-year-old girl with neurological complications associated EBV-induced HLH. Her cerebral magnetic resonance imaging (MRI) showed contrast-enhanced axial T1-weighted images with enhancement of meningeal surface in the right hemisphere that was consistent with right hemi-meningitis. Hydrocephalus, dilated subdural spaces, delayed myelination, edema, diffuse parenchymal atrophy, calcifications, diffuse/patchy white matter abnormalities have all been previously described with HLH. To the best of our knowledge, this is the first case of hemi-meningitis associated with HLH. We suggest that clinicians should consider HLH with vascular disorders when they determine unilateral meningitis on a brain MRI.
authors: Department of Pediatric Neurology, Eskisehir Osmangazi University Hospital, Eskisehir, Turkey.
authors: Ozan
authors: O
authors: Kocak
authors: Department of Pediatric Neurology, Eskisehir Osmangazi University Hospital, Eskisehir, Turkey.
authors: Coskun
authors: C
authors: Yarar
authors: Department of Pediatric Neurology, Eskişehir State Hospital, Eskisehir, Turkey.
authors: Sevgi
authors: S
authors: Yimenicioğlu
authors: Department of Pediatric Neurology, Bursa Sevket Yilmaz Education and Research Hospital, Bursa, Turkey.
authors: Arzu
authors: A
authors: Ekici
authors: Department of Pediatric Hematology, Eskisehir Osmangazi University Hospital, Eskisehir, Turkey.
authors: Özcan
authors: Ö
authors: Bör
keywords: Epstein-Barr virus; hemi-meningitis; hemophagocytic lymphohistiocytosis; hemophagocytic syndrome