title: Changes in chorioretinal blood flow velocity and cerebral blood flow after carotid endarterectomy.
abstract: OBJECTIVE
  To investigate the changes in chorioretinal blood flow velocity and cerebral blood after carotid endarterectomy (CEA).
  
  
  METHODS
  Nine patients with moderate to severe internal carotid artery stenosis underwent CEA. Chorioretinal blood flow velocity was measured by laser speckle flowgraphy (LSFG), while cerebral blood flow (CBF) was measured by single-photon emission computed tomography (SPECT), on the affected side both before and after CEA. LSFG was evaluated in five areas to determine mean blur rate, while CBF was calculated from regional CBF and cerebrovascular reactivity (CVR), at the middle cerebral artery (MCA) region of each patient.
  
  
  RESULTS
  Five cases showed an increase (mean 3.49 %, range -29.82 to 35.59 %) of average chorioretinal blood flow velocity using LSFG after CEA. A particularly averaged increase in chorioretinal blood flow was observed in the macular area compared with other areas. Similarly, there was an increase in CBF at rest (mean 11.46 %, range -14.51 to 74.14 %) observed using SPECT after surgery. Improvement of CVR was confirmed in four cases. All general and visual symptoms disappeared after CEA. Severe adverse effects, including hyperperfusion syndrome, were not observed in any cases.
  
  
  CONCLUSIONS
  LSFG may be useful for the analysis of chorioretinal blood flow changes after CEA.
authors: Department of Ophthalmology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan. enaida@cc.saga-u.ac.jp.
authors: Hiroshi
authors: H
authors: Enaida
authors: Department of Neurosurgery, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan.
authors: Shinji
authors: S
authors: Nagata
authors: Department of Ophthalmology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan.
authors: Atsunobu
authors: A
authors: Takeda
authors: Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
authors: Shintaro
authors: S
authors: Nakao
authors: Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
authors: Yasuhiro
authors: Y
authors: Ikeda
authors: Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
authors: Tatsuro
authors: T
authors: Ishibashi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity / Q000502:physiology*; D016893:Carotid Stenosis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002829:Choroid / Q000098:blood supply*; D016894:Endarterectomy, Carotid / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012160:Retina / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012189:Retrospective Studies; D015899:Tomography, Emission-Computed, Single-Photon
keywords: Carotid endarterectomy (CEA); Cerebral blood flow; Chorioretinal blood flow velocity; Laser speckle flowgraphy (LSFG); Single photon emission computed tomography (SPECT)