title: Intermolecular C-H Quaternary Alkylation of Aniline Derivatives Induced by Visible-Light Photoredox Catalysis.
abstract: The intermolecular direct C-H alkylation of aniline derivatives with α-bromo ketones to build a quaternary carbon center was reported with a visible-light catalysis procedure. The reaction covers a variety of functional groups with good to excellent yields. A regioselectivity favoring the ortho position for the amine group was observed and investigated with Fukui indices and spectral methods.
authors: Institute of Chemistry and Biomedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210023, China.
authors: Jie
authors: J
authors: Cheng
authors: Institute of Chemistry and Biomedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210023, China.
authors: Xia
authors: X
authors: Deng
authors: Institute of Theoretical and Computational Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210023, China.
authors: Guoqiang
authors: G
authors: Wang
authors: Institute of Chemistry and Biomedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210023, China.
authors: Ying
authors: Y
authors: Li
authors: Institute of Chemistry and Biomedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210023, China.
authors: Xu
authors: X
authors: Cheng
authors: Institute of Chemistry and Biomedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210023, China.|Department of Chemistry and Biochemistry, Texas Tech University , Lubbock, Texas 79409, United States.
authors: Guigen
authors: G
authors: Li