Pseudomonal Biofilm Topographic Distribution on Tympanostomy Tubes: An In Vitro Model.
In vitro growth of Pseudomonas aeruginosa biofilm on tympanostomy tubes showed that in Armstrong T-tubes, biofilm colonies were mainly located in the perpendicular junction between the body and the flanges, but in Paparella-type tube, they concentrated on the round rims. These "weakness" zones can be the future target areas for geometry changes, and can be specifically coated with antibiofilm materials.
From the *Maccabi HMO, Tel Aviv, Israel; †Department of Otolaryngology-Head and Neck Surgery, Assaf Harofeh Medical Center, Tel Aviv University, Sackler Faculty of Medicine, Zerifin, Israel; ‡Biofilm Research Laboratory, Bio-Medical Program, Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Sharon
S
Ovnat Tamir
Tal
T
Marom
Batya
B
Zaks
Doron
D
Steinberg
D001422:Bacterial Adhesion; D018441:Biofilms; D006801:Humans; D008876:Middle Ear Ventilation / Q000295:instrumentation*; D008954:Models, Biological; D010033:Otitis Media / Q000382:microbiology; D019736:Prostheses and Implants / Q000382:microbiology*; D011550:Pseudomonas aeruginosa