Detoxification of Chemical Warfare Agents Using a Zr6-Based Metal-Organic Framework/Polymer Mixture.
Owing to their high surface area, periodic distribution of metal sites, and water stability, zirconium-based metal-organic frameworks (Zr6-MOFs) have shown promising activity for the hydrolysis of nerve agents GD and VX, as well as the simulant, dimethyl 4-nitrophenylphosphate (DMNP), in buffered solutions. A hurdle to using MOFs for this application is the current need for a buffer solution. Here the destruction of the simulant DMNP, as well as the chemical warfare agents (GD and VX) through hydrolysis using a MOF catalyst mixed with a non-volatile, water-insoluble, heterogeneous buffer is reported. The hydrolysis of the simulant and nerve agents in the presence of the heterogeneous buffer was fast and effective.
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208-3113, USA.
Su-Young
SY
Moon
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208-3113, USA.
Emmanuel
E
Proussaloglou
Edgewood Chemical Biological Center, US Army Research, Development, and Engineering Command, 5183 Blackhawk Road, Aberdeen Proving Ground, MD, 21010, USA.
Gregory W
GW
Peterson
Edgewood Chemical Biological Center, US Army Research, Development, and Engineering Command, 5183 Blackhawk Road, Aberdeen Proving Ground, MD, 21010, USA.
Jared B
JB
DeCoste
Edgewood Chemical Biological Center, US Army Research, Development, and Engineering Command, 5183 Blackhawk Road, Aberdeen Proving Ground, MD, 21010, USA.
Morgan G
MG
Hall
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208-3113, USA.
Ashlee J
AJ
Howarth
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208-3113, USA. j-hupp@northwestern.edu.
Joseph T
JT
Hupp
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208-3113, USA. o-farha@northwestern.edu.|Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia. o-farha@northwestern.edu.
Omar K
OK
Farha
heterogeneous buffer; heterogeneous catalysis; hydrolysis; nerve agents; zirconium MOF