Pathogenicity of virulent infectious bronchitis virus isolate YN on hen ovary and oviduct.
Avian infectious bronchitis is an economically important poultry disease caused by avian infectious bronchitis virus (IBV). IBV isolate YN is a virulent strain, which is genetically similar to most of the prevalent strains in China. In this study, 21-day-old commercial laying hens were infected with IBV strain YN. The damaging effects of the virus on the reproductive organs were evaluated with clinical observations, gross autopsy and histopathological examinations during the 100-day monitoring period post infection. IBV strain YN infection caused a death rate of 40.5%. Microscopic lesions were observed on the ovary post-infection, but were restricted to the acute infection period. The pathological damage to the cystic oviducts were observed throughout the surveillance period. This study provides detailed information on the pathological changes in the hen ovary and oviduct after challenge with IBV strain YN, which could provide a better understanding about the pathogenicity of IBV.
Key Laboratory of Animal Epidemiology and Zoonoses, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.
Qi
Q
Zhong
Key Laboratory of Animal Epidemiology and Zoonoses, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.
Yan-Xin
YX
Hu
Key Laboratory of Animal Epidemiology and Zoonoses, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.
Ji-Hui
JH
Jin
Key Laboratory of Animal Epidemiology and Zoonoses, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.
Ye
Y
Zhao
Key Laboratory of Animal Epidemiology and Zoonoses, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China.
Jing
J
Zhao
Key Laboratory of Animal Epidemiology and Zoonoses, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China. Electronic address: zhanggz@cau.edu.cn.
Guo-Zhong
GZ
Zhang
D000818:Animals; D002645:Chickens / Q000821:virology*; D002681:China; D018352:Coronavirus Infections / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D005260:Female; D001351:Infectious bronchitis virus / Q000302:isolation & purification / Q000472:pathogenicity*; D010053:Ovary / Q000473:pathology / Q000821:virology; D010057:Oviducts / Q000473:pathology / Q000821:virology; D011201:Poultry Diseases / Q000473:pathology* / Q000821:virology; D014774:Virulence
Infectious bronchitis virus; Ovary; Oviduct; Pathogenicity