Suprasellar Clear Cell Meningioma in an Infant.
Clear cell meningiomas are an uncommon subtype of meningioma rarely seen in infancy. We report a case of clear cell meningioma in an 8-month-old male infant. He presented at the Lagos University Teaching Hospital, Lagos, Nigeria, in 2015 with persistent vomiting, poor feeding and failure to thrive over a four month period. Generalised hypertonia and hyperreflexia were noted on examination. Computed tomography of the brain revealed a huge largely isodense suprasellar mass with a hypodense core. The tumour, which measured 6 × 5 × 4 cm, enhanced non-uniformly with contrast injection and extended to occlude the third ventricle. The patient underwent a bifrontal craniotomy with subtotal tumour excision. Six hours postoperatively, he went into cardiac arrest and could not be resuscitated. A histological diagnosis of clear cell meningioma was made as the tumour cells were immunoreactive to epithelial membrane antigen, S100 protein and vimentin. This case of clear cell meningioma was unusual due to its early occurrence and supratentorial location.
Department of Anatomic & Molecular Pathology, College of Medicine, University of Lagos, Lagos, Nigeria;
Charles C
CC
Anunobi
Departments of Neurosurgery, Lagos University Teaching Hospital, Lagos, Nigeria.
Olufemi
O
Bankole
Anatomic & Molecular Pathology, Lagos University Teaching Hospital, Lagos, Nigeria.
Nzechukwu Z
NZ
Ikeri
Departments of Neurosurgery, Lagos University Teaching Hospital, Lagos, Nigeria.
Nurudeen A
NA
Adeleke
Brain Tumor; Case Report; Central Nervous System Tumors; Clear Cell Meningioma; Infant; Nigeria