Minimally Invasive Lumbar Pedicle Screw Fixation Using Cortical Bone Trajectory - A Prospective Cohort Study on Postoperative Pain Outcomes.
OBJECTIVE
Our study aims to evaluate the clinical outcomes of cortical screws in regards to postoperative pain.


BACKGROUND
Pedicle screw fixation is the current mainstay technique for posterior spinal fusion. Over the past decade, a new technique called cortical screw fixation has been developed, which allows for medialized screw placement through stronger cortical bone. There have been several studies that showed either biomechanical equivalence or superiority of cortical screws. However, there is currently only a single study in the literature looking at clinical outcomes of cortical screw fixation in patients who have had no prior spine surgery.


METHODS
We prospectively looked at the senior author's patients who underwent cortical versus pedicle lumbar screw fixation surgeries between 2013 and 2015 for lumbar degenerative disease. Eighteen patients underwent cortical screw fixation, and 15 patients underwent traditional pedicle screw fixation. We looked at immediate postoperative pain, changes in short-term pain (six to 12 weeks post-surgery), and changes in long-term pain (six to eight months). All pain outcomes were measured using a visual analog scale ranging from 1 to 10. Mann-Whitney or Kruskal-Wallis tests were used to measure continuous data, and the Fisher Exact test was used to measure categorical data as appropriate.


RESULTS
Our results showed that the cortical screw cohort showed a trend towards having less peak postoperative pain (p = 0.09). The average postoperative pain was similar between the two cohorts (p = 0.93). There was also no difference in pain six to 12 weeks after surgery (p = 0.8). However, at six to eight months, the cortical screw cohort had worse pain compared to the pedicle screw cohort (p = 0.02).


CONCLUSIONS
The cortical screw patients showed a trend towards less peak pain in the short-term (one to three days post-surgery) and more pain in the long-term (six to eight months post-surgery) compared to pedicle screw patients. Both cohorts had a statistically significant reduction in pain levels compared to preoperative pain. More studies are needed to further evaluate postoperative pain, long-term functional outcomes, and fusion rates in patients who undergo cortical screw fixation.
Department of Neurosurgery, Stanford University Medical Center.
Yi-Ren
YR
Chen
Medical School, Stanford University School of Medicine.
Sayantan
S
Deb
Department of Neurosurgery, Stanford University Medical Center.
Lan
L
Pham
Department of Neurosurgery, Stanford University Medical Center.
Harminder
H
Singh
cortical screws; outcomes; postoperative pain; prospective cohort study