Nonproliferative and Proliferative Lesions of the Rat and Mouse Skeletal Tissues (Bones, Joints, and Teeth).
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is an initiative of the Societies of Toxicological Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in the skeletal tissues and teeth of laboratory rats and mice, with color photomicrographs illustrating examples of many common lesions. The standardized nomenclature presented in this document is also available on the internet (http://www.goreni.org/). Sources of material were databases from government, academic and industrial laboratories throughout the world.
AbbVie Inc., North Chicago, IL, USA.
Stacey
S
Fossey
Lilly Research Laboratories, Indianapolis, IN, USA.
John
J
Vahle
Vet Path Services, Inc., Mason, OH, USA.
Philip
P
Long
Pfizer Inc., Andover, MA, USA; Dr. Schelling retired April 2015.
Scott
S
Schelling
Fraunhofer Institute, Hannover, Germany.
Heinrich
H
Ernst
Amgen Inc., Thousand Oaks, CA, USA.
Rogely Waite
RW
Boyce
Charles River Laboratories, Senneville, Canada.
Jacquelin
J
Jolette
GEMpath Inc., Longmont, CO, USA.
Brad
B
Bolon
Bolder BioPath, Inc., Boulder, CO, USA.
Alison
A
Bendele
Bayer Pharma AG, Wuppertal, Germany.
Matthias
M
Rinke
LNH Tox Path Consulting, LLC, Kalamazoo, MI, USA.
Laura
L
Healy
WB High Preclin Path/Tox Consulting, LLC, Rochester, NY, USA.
Wanda
W
High
AbbVie Inc., North Chicago, IL, USA.
Daniel Robert
DR
Roth
Amgen Inc., Thousand Oaks, CA, USA.
Michael
M
Boyle
JRL Consulting, LLC, Chapel Hill, NC, USA; Chair of the Skeletal Tissues INHAND Committee.
Joel
J
Leininger
bone; diagnostic criteria; diagnostic pathology; joint; nomenclature; skeletal system; tooth