Follow-Up Results of Device Occlusion of Patent Ductus Arteriosus.
BACKGROUND
Transcatheter patent ductus arteriosus (PDA) closure is an established procedure.


OBJECTIVE
The aim of the study was to assess midterm follow up of the Nit-Occlud coil and the amplatzer ductal occluder (ADO) closure of PDA.


METHODS
In this cohort study, we collected the longitudinal data of patients who underwent percutaneous closure using coil or ADO from November 2005 to November 2013. A total of 404 patients with PDA closure by devices were included during the study period. Coil occlusion was performed in 220 patients and 184 patients underwent catheterization using ADO. Follow-up evaluations were performed with echocardiography at two weeks, two months, six months, and during the study period (in average 4.8 ± 3.8 years).


RESULTS
The patients' mean age was 24 months (range: 1 - 312). The catheterization was successful in 393 (97.2%) patients and unsuccessful in 11 (2.7%). Immediate complete occlusion was seen in 290 (73.7 %) patients. The occlusion rates at two weeks, two months, six months, and during the study period were 73.7%, 84%, 93.6%, 98.7%, and 99.5%, respectively. Complications occurred in 23 (5.8%) patients during or immediately after the catheterization, and device embolization with 2.7% was the most common complication. Most complications occurred in a patient with pulmonary hypertension who was less than one year old and was undergoing the first year of experience with devices.


CONCLUSIONS
Our findings showed that transcatheter occlusion of the PDA is an effective and safe intervention by coil or Amplatzer with excellent early and one-year outcomes. Pulmonary hypertension, age of less than 12 months and experience of less than one year may increase the complications of device closure.
Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Hamid
H
Amoozgar
Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Sara
S
Salehi
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Pouya
P
Farhadi
Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Mohammad Reza
MR
Edraki
Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Mohammad
M
Borzoee
Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Gholamhossein
G
Ajami
Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Sirous
S
Cheriki
Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Hamid
H
Mohammadi
Amplatzer Ductal Occlude; Coil Occlusion; Patent Ductus Arteriosus; Transcatheter Occlusion; Treatment Outcome