Intellectual Disability: When the Hypertrichosis Is a Clue.
The skin and the central and peripheral nervous system both derive from the ectoderm ridge. Therefore, several syndromes characterized by the presence of intellectual disability (ID) can be associated with specific congenital cutaneous manifestations. In this review, we list some of the most frequent diseases characterized by the presence of ID associated with hirsutism, which might be an incentive for the clinicians to pay attention to the ectodermal annexes in patients with ID.
Pathology Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Lidia
L
Pezzani
Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Donatella
D
Milani
Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Unit of Dermatology, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Gianluca
G
Tadini
hair; hirsutism; hypertrichosis; intellectual disability