Safety of Bronchoscopy in Patients with Echocardiographic Evidence of Pulmonary Hypertension.
BACKGROUND
Bronchoscopy with transbronchial and endobronchial biopsy and transbronchial needle aspiration is an important diagnostic tool in the pulmonologist's armamentarium. Safety in patients with pulmonary hypertension is controversial and many bronchoscopists consider this as a contraindication for the procedure.


OBJECTIVE
To evaluate safety of bronchoscopy in patients with echocardiographic pulmonary hypertension and to compare with patients without it.


METHODS
Retrospective analysis of patients who underwent bronchoscopic transbronchial biopsy, endobronchial biopsy and/or endobronchial ultrasound-guided transbronchial needle aspiration. Patients were divided into two groups based on echocardiographic results: control group with systolic pulmonary artery pressure <36 and a group with elevated systolic pulmonary artery pressure (eSPAP) ≥36.


RESULTS
One-hundred and ninety patients met the study criteria. Patients in the control group were younger with a lower incidence of chronic kidney disease. There was no difference in prevalence of congestive heart failure, obstructive airway disease, malignancy, liver disease, coagulopathy, use of antiplatelet agent or anticoagulant drugs. Incidence of minor bleeding due to bronchoscopic biopsies was 4.8% in both groups (p = 1.00). Incidence of major bleeding was similar in the groups (one patient in each group). In the control group, one patient had pneumothorax and another required prolonged mechanical ventilation (>4 h). In the eSPAP group, two patients required prolonged mechanical ventilation. There was no procedure-related mortality or sedation complications in the cohort.


CONCLUSIONS
Our study provides additional support that in patients with echocardiographic evidence of pulmonary hypertension, transbronchial and endobronchial biopsies and endobronchial ultrasound-guided transbronchial needle aspiration are safe procedures.
Division of Pulmonary and Critical Care Medicine, Bronx-Lebanon Hospital Center, Bronx, N.Y., USA.
Gilda
G
Diaz-Fuentes
Bharat
B
Bajantri
Muhammad
M
Adrish
D000328:Adult; D000368:Aged; D001706:Biopsy; D001999:Bronchoscopy; D016022:Case-Control Studies; D004452:Echocardiography; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011030:Pneumothorax / Q000453:epidemiology*; D011183:Postoperative Complications / Q000453:epidemiology*; D019106:Postoperative Hemorrhage / Q000453:epidemiology*; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000453:epidemiology*; D012189:Retrospective Studies