[Maternal-fetal transmission of Trypanosoma cruzi, a health problem slightly studied in Mexico: case Chiapas].
OBJECTIVE
To determine the Trypanosoma cruzi infection prevalence in 1125 pregnant women and the transmission frequency to their children from Tapachula and Palenque, Chiapas.


METHODS
We determined the prevalence by serology tests and the transmission frequency by polymerase chain reaction (PCR) and T. cruzi reactivity capacity after 12 months.


RESULTS
Total maternal infection prevalence were 23/1 125 (2.04%), 9/600 (1.5%) were from Tapachula and 14/525 (2.6%) from Palenque. The seropositive women were between 20 and 35 years old, 31.8% have Premature Rapture of Membrane and 9.1% have history of perinatal death. The total percentage of positive newborns by PCR was 9/23 (39.13%), out of those 2/9 (22.2%) are from Tapachula and 7/14 (50%) from Palenque. The Maternal Fetal transmission frequency was. 2/9 (22.2%) in Tapachula and 1/14 (7.14%) in Palenque, all positive infants were asynthomatic.


CONCLUSIONS
The maternal-fetal transmission rate in Chiapas State is variable; the reason could be the maternal immunological status and T. cruzi strain.
Guillermina
G
Campos-Valdez
Luis Miguel
LM
Canseco-Ávila
Fernando
F
González-Noriega
Oscar
O
Alfaro-Zebadua
Ismael Yadird
IY
Nava-Medecigo
Enedina
E
Jiménez-Cardoso
D000328:Adult; D058070:Asymptomatic Diseases; D014355:Chagas Disease / Q000453:epidemiology / Q000635:transmission*; D005260:Female; D062306:Geography, Medical; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000706:statistics & numerical data; D008297:Male; D008800:Mexico / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D011256:Pregnancy Outcome; D016036:Seroepidemiologic Studies; D014349:Trypanosoma cruzi / Q000276:immunology; D055815:Young Adult