The Effect of Body Mass Index on Spirometric Parameters in Children with Asthma.
OBJECTIVE
Asthma and obesity represent one of the most crucial public and health problems of modern society that frequently begin in childhood and have some mutual elements of risk. Abdominal distribution of connective tissue is important determinant which brings to decrease of lungs function. Multiple influence of overweight on function of the lungs would clearly manifest over reduction of forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC).


METHODS
Examining was conducted at Pediatric Clinic of University Clinical Hospital Tuzla during the year 2013/2014. Research included 60 children with diagnosed asthma who were in relation to BMI were divided in 3 groups. The first group was children with BMI ranging from 5 to 85 percentile, the second were children with 85 to 95 percentile and the third was 95 percentile. By prospective study, compared identical pulmonary variable for all three age group of asthma patients were analyzed, the children with normal body mass a well as the overweight and the obese.


RESULTS
At the beginning of testing, the frequency of normal spirometric findings was significantly lower in the obese group in comparison with other two observed groups (p<0,05). The only cases of mixed and restrictive disorder of ventilation were registered in the obese group of tested at the beginning of the examined (p<r0,001).


CONCLUSIONS
When being compared the values of spirometric parameters before and after the research, the only significant difference was in the obese group, the values after tests were significantly higher, with the exception of relation FEV1/FVC, that had the same distribution of values before and after research. However, the group with normal body mass and overweight, had all the spirometric parameters with equal distribution before and after research (p>0,05 for all measurements).
Department of Pediatrics, University Clinical Center Tuzla, Bosnia and Herzegovina.
Amela
A
Pasic
Department of Pediatrics, University Clinical Center Tuzla, Bosnia and Herzegovina.
Fahrija
F
Skokic
Department of Surgery, University Clinical Center Tuzla, Bosnia and Herzegovina.
Fuad
F
Pasic
Institute for Pulmonary Diseases of Vojvodina, Novi Sad, Serbia.
Miroslav
M
Ilic
D000293:Adolescent; D001249:Asthma / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D015992:Body Mass Index; D017522:Bosnia and Herzegovina; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D056865:Ideal Body Weight / Q000502:physiology*; D008297:Male; D050177:Overweight / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D063766:Pediatric Obesity / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D011446:Prospective Studies; D013147:Spirometry / Q000379:methods*
asthma; children; obesity; spirometry