Beige Communication through Gap Junctions and Adaption by Autophagy.
How thermogenic stimuli activate and control beige adipocytes is not fully understood. In this issue, Zhu et al. (2016) and Altshuler-Keylin et al. (2016) provide insights into these important issues by demonstrating roles for connexin 43 (Cx43) atg5 and atg12 in signal propagation and phenotypic adaptation in beige adipocytes.
Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, Medicinaregatan 9A, P.O. Box 440, 405 30 Göteborg, Sweden. Electronic address: sven.enerback@medgen.gu.se.
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D000064:Acclimatization; D001343:Autophagy; D002450:Cell Communication; D017629:Gap Junctions; D006801:Humans