Violent behavior and aggression in schizophrenia: Prevalence and risk factors. A multicentric study from three Latin-America countries.
The aim of the present study was (i) to assess the prevalence of Violent Behavior in Schizophrenia (VBS) in a sample of community-dwelling outpatients in three middle-income countries of Latin America and (ii) to determine the clinical and socio-demographical risk factors associated with VBS and aggression level.



The study included 253 stabilized outpatients with schizophrenia and their principal caregivers from 3 public ambulatory psychiatric care centers in Bolivia (N=83), Chile (N=85), and Peru (N=85). VBS was defined according to the Overt Aggression Scale (OAS) score and the aggression level was measured by the aggression subscore of the Agitated Behavior Scale of Corrigan. We collected socio-demographic information and clinical data. Multiple linear and logistic regressions were performed to determine which variables were associated with VBS and aggression level.



The prevalence of VBS differed statistically between the three countries (p<0.001) with 3.5% in Chile, 14.6% in Peru and 55.4% in Bolivia. After adjustment for confounding factors, VBS was associated with a younger age, a more severe psychotic symptomatology, a lower family income and unemployment. After adjustment for confounding factors, aggression level was associated with a more severe psychotic symptomatology, a lower family income, a younger age at illness onset and higher number of hospitalizations in the last 3years.



These results may guide future health policies to specifically provide social support and rehabilitation care to VBS patients in middle-income countries, including psychoeducation and a more integrated work between the treating medical team and the social workers.
Universidad de Tarapacá, Avenida 18 de Septiembre 2222, Arica, Chile; Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, United States. Electronic address: acaqueo@uta.cl.
Alejandra
A
Caqueo-Urízar
Université Paris Est-Créteil, Pôle de psychiatrie des hôpitaux universitaires H Mondor, INSERM U955, Eq Psychiatrie Translationnelle, DHU Pe-Psy, France; Fondation FondaMental Fondation de coopération scientifique en santé mentale, France. Electronic address: guillaume.fond@inserm.fr.
Guillaume
G
Fond
Universidad Católica del Norte, Avda. Angamos 0610, Antofagasta, Chile. Electronic address: alurzua@ucn.cl.
Alfonso
A
Urzúa
Aix-Marseille Univ, EA 3279 - Public Health, Chronic Diseases and Quality of Life - Research Unit, 13005 Marseille, France. Electronic address: Laurent.BOYER@ap-hm.fr.
Laurent
L
Boyer
Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, United States; Department of African and African American Studies, Harvard University, Cambridge, MA, United States. Electronic address: dwilliam@hsph.harvard.edu.
David R
DR
Williams
D000328:Adult; D000374:Aggression; D000553:Ambulatory Care; D001838:Bolivia / Q000453:epidemiology; D017028:Caregivers; D002677:Chile / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006760:Hospitalization; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D010045:Outpatients; D010568:Peru / Q000453:epidemiology; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012559:Schizophrenia / Q000453:epidemiology* / Q000628:therapy; D012959:Socioeconomic Factors; D014754:Violence
Aggression; Schizophrenia; Violent behavior