[Conformal radiotherapy for vertebral bone metastasis].
Analgesic external beam radiation therapy is a standard of care for patients with uncomplicated painful bone metastases and/or prevention of bone complications. In case of fracture risk, radiation therapy is performed after surgery in a consolidation of an analgesic purpose and stabilizing osteosynthesis. Radiotherapy is mandatory after vertebroplasty or kyphoplasty. Spinal cord compression - the only emergency in radiation therapy - is indicated postoperatively either exclusively for non surgical indication. Analgesic re-irradiation is possible in the case of insufficient response or recurrent pain after radiotherapy. Metabolic radiation, bisphosphonates or denosumab do not dissuade external radiation therapy for pain relief. Systemic oncological treatments can be suspended with a period of wash out given the risk of radiosensitization or recall phenomenon. Better yet, the intensity modulated radiotherapy and stereotactic radiotherapy can be part of a curative strategy for oligometastatic patients and suggest new treatment prospects.
Département universitaire de radiothérapie - curiethérapie, institut de cancérologie de Lorraine, Alexis-Vautrin, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France. Electronic address: jeanchristophe.faivre@gmail.com.
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JC
Faivre
Département universitaire de radiothérapie - curiethérapie, institut de cancérologie de Lorraine, Alexis-Vautrin, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France.
J F
JF
Py
Département universitaire de radiothérapie - curiethérapie, institut de cancérologie de Lorraine, Alexis-Vautrin, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France.
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Vogin
CRISTAL UMR CNRS 9189, département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Frédéric-Combemale, 59000 Lille, France.
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Martinage
Département biostatistiques et méthodologie, institut de cancérologie de Lorraine, Alexis-Vautrin, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France.
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J
Salleron
Département universitaire de radiothérapie - curiethérapie, institut de cancérologie de Lorraine, Alexis-Vautrin, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France.
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Royer
Département universitaire de radiothérapie - curiethérapie, institut de cancérologie de Lorraine, Alexis-Vautrin, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France.
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Grandgirard
CRISTAL UMR CNRS 9189, département universitaire de radiothérapie, centre Oscar-Lambret, université de Lille, 3, rue Frédéric-Combemale, 59000 Lille, France.
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Pasquier
Département de radiothérapie et de physique médicale, centre Henri-Becquerel, Quantif-Litis EA 4108, 76038 Rouen, France.
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Thureau
D001416:Back Pain / Q000209:etiology / Q000628:therapy; D019299:Decompression, Surgical; D006801:Humans; D058958:Organs at Risk; D010353:Patient Education as Topic; D011788:Quality of Life; D020266:Radiotherapy, Conformal; D061089:Radiotherapy, Image-Guided; D013117:Spinal Cord Compression / Q000209:etiology / Q000532:radiotherapy / Q000601:surgery; D013125:Spinal Neoplasms / Q000150:complications / Q000532:radiotherapy* / Q000556:secondary*
Bone metastasis; Conformal; Douleur; Intensity-modulated; Métastase osseuse; Pain; Radiotherapy; Radiothérapie; Soins oncologiques de supports; Spine; Supportive care; Vertèbre