Discovery of a novel HLA-B*15 allele, HLA-B*15:379, in a patient from Guinea-Bissau.
HLA-B*15:379 differs from HLA-B*15:03:01:01 by a c.T539G substitution in exon 3.
Bandim Health Project, Indepth Network, Bissau, Guinea-Bissau.|Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
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Thomsen
Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark. Mette.Christiansen@rm.dk.
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0000-0001-5158-3670
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Christiansen
National HIV Programme, Ministry of Health, Bissau, Guinea-Bissau.
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Medina
Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
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Erikstrup
Bandim Health Project, Indepth Network, Bissau, Guinea-Bissau.|Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
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Hønge
D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D003062:Codon / Q000737:chemistry; D005091:Exons; D005838:Genotype; D006169:Guinea-Bissau; D015658:HIV Infections / Q000276:immunology / Q000821:virology; D015498:HIV-2 / Q000302:isolation & purification; D059910:HLA-B15 Antigen / Q000235:genetics* / Q000276:immunology; D006650:Histocompatibility Testing; D006801:Humans; D033162:Incidental Findings; D008297:Male; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
D003062:Codon; D059910:HLA-B15 Antigen
HLA-B*15:379; human leukocyte antigen; next generation sequencing; novel allele