[Epidemiology of the infection by resistant Gram-positive microorganisms].
Resistance among Gram-positive microorganisms to classical and new antimicrobials is a therapeutic threat. In Spain, methicillin resistance among Staphylococcus aureus (25-30%) and coagulase-negative staphylococci (50-60%) seems to have stabilized in the last decade. Among enterococci, vancomycin resistance is less than 5%. Both linezolid and daptomycin, in general, show good activity against these microorganisms. However, the resistance rates of Staphylococcus epidermidis to linezolid (20.9%), and of Enterococcus faecium to daptomycin (10.5%) in isolates from intensive care units are a worrying.
Emilia Cercenado, Servicio de Microbiología y Enfermedades Infecciosas Hospital General Universitario Gregorio Marañón Dr Esquerdo 46; 28007 Madrid, Spain. emilia.cercenado@salud.madrid.org.
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Cercenado
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D013293:Enterococcus faecalis / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology; D013210:Staphylococcus / Q000187:drug effects
D000900:Anti-Bacterial Agents