Dearomatization-Induced Cycloaddition and Aromatization-Triggered Rearrangement: Synthesis of Vertically Expanded Five-Ring Fused Benzofurans.
A dearomatization strategy has been developed for the efficient construction of vertically expanded five-ring fused benzofurans from ortho-alkynylphenols and ortho-alkynylarylaldimines. The stepwise procedure comprises a dearomatization-induced silver-catalyzed [3 + 2] cycloaddition followed by an aromatization-triggered ytterbium-catalyzed rearrangement.
Department of Chemistry, Fudan University , 220 Handan Road, Shanghai, 200433, China.
Dandan
D
Han
Department of Child Health Care, Shanghai Children's Hospital Affiliated to Shanghai Jiao Tong University , 1400 Beijing Xi Road, Shanghai, 200040, China.
Jinjin
J
Chen
Department of Chemistry, Fudan University , 220 Handan Road, Shanghai, 200433, China.
Qiuqin
Q
He
Department of Chemistry, Fudan University , 220 Handan Road, Shanghai, 200433, China.
Renhua
R
Fan