Study of Association of Atherosclerotic Risk Factors and Metabolic Syndrome in Patients of Psoriasis at a Tertiary Care Centre in North India: A Case Control Study.
OBJECTIVE
To study the association between psoriasis and atherosclerotic risk factors, including metabolic syndrome.


METHODS
Fifty patients with psoriasis and 50 controls were included in the study. Atherosclerotic risk factors were evaluated as per National Cholesterol Education Project Adult Treatment Panel III (NCEP-ATPIII). Metabolic syndrome was diagnosed as per South Asian Modified -National Cholesterol Education Programme's Adult Treatment Panel III (ATP III).


RESULTS
Psoriatic patients had a significantly higher prevalence of hypertriglyceridaemia (≥150 mg/dl) (p=0.013), low HDL (< 40mg/dl) (p=0.025), impaired fasting blood glucose (≥100 mg/dl) (p=0.026). Metabolic syndrome was present in significant number of psoriasis patients than in controls [42 (28%) versus 9 (6%)] (P=0.009).


CONCLUSIONS
There is a significantly higher prevalence of metabolic syndrome and atherosclerotic risk factors in psoriasis patients as compared to controls.
IIIrd Year Junior Resident.
Satish Chand
SC
Sharma
Professor and Head, Dept. of Dermatology.
Prafulla Kumar
PK
Sharma
Asstt. Professor, Dept.of Medicine, P.G.I.M.E.R. Dr. R.M.L. Hospital, New Delhi Received: 02.06.2014; Revised: 14.07.2014; Accepted: 22.07.2014.
R K
RK
Dudeja