Spontaneous Resolution of a Central Giant Cell Granuloma in a Child After an Incisional Biopsy: A Five-year Follow-up.
A central giant cell granuloma (CGCG) is typically regarded as a benign lesion with osteoclastic activity. Treatment often involves surgical procedures that may cause deformities; however, minimally invasive approaches have been suggested for treating pediatric patients. We report a case of CGCG of the mandible in a 13-year-old boy who presented with a well-defined radiolucent area in the anterior mandible that was initially detected in a radiographic examination for orthodontic purposes. An incisional biopsy was performed and diagnosed histologically as a CGCG. The patient underwent clinical and radiographic follow-up only after the biopsy, eventually showing signs of bone healing. Five years later, complete resolution of the lesion was observed radiographically. Considering this optimal outcome, similar cases of CGCG should be carefully analyzed for appropriateness of this conservative approach.
Department of Stomatology, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
Ademir
A
Franco
Department of Endodontics, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
André V K
AV
Segato
Department of Stomatology, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
Soraya A B
SA
Couto
Department of Oral Pathology, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
Aline Cristina Batista
AC
Rodrigues Johann
Veterans Affairs Greater Los Angeles Healthcare System, Department of Oral and Maxillofacial Surgery, University of California at Los Angeles, School of Dentistry, Los Angeles, Calif., USA.
Arthur H
AH
Friedlander
Department of Stomatology and Oral Radiology, School of Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil. couto.s@pucpr.br.
Paulo H
PH
Couto Souza
D000293:Adolescent; D001706:Biopsy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*