Monocyte count-to-high-density lipoprotein-cholesterol ratio is associated with abdominal aortic aneurysm size.
OBJECTIVE
To determine the association of monocyte count-to-high-density lipoprotein (HDL)-cholesterol ratio, a recently emerged inflammatory marker, with abdominal aortic aneurysm (AAA) size.


METHODS
A total of 120 asymptomatic AAA subjects (99 male, mean age: 67.1 ± 10.2 years) were enrolled into the study. All data were compared between patients with low and high admission monocyte/HDL ratio. Multivariate linear regression analysis was performed to study the relationship between different variables and AAA size.


RESULTS
Compared to patients with below-median monocyte/HDL ratio, aneurysm diameter was significantly higher in above-median monocyte/HDL ratio group (54.3 ± 10.6 mm vs 62.0 ± 12.4 mm, p < 0.001, respectively). Hypertension, coronary artery disease, monocyte/HDL ratio and C-reactive protein were independently associated with AAA diameter.


CONCLUSIONS
Monocyte/HDL ratio is independently associated with AAA size.
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey.
Kumral
K
Cagli
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey.
Derya
D
Tok
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey.
Osman
O
Turak
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey.
Eren
E
Gunertem
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey.
Cagri
C
Yayla
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey.
Gokhan
G
Lafci
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey.
Mahmut Mustafa
MM
Ulas
Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey.
Kerim
K
Cagli
D000368:Aged; D001012:Aorta, Abdominal / Q000503:physiopathology; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis* / Q000209:etiology; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D003324:Coronary Artery Disease / Q000150:complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D016014:Linear Models; D008075:Lipoproteins, HDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000166:cytology*; D015999:Multivariate Analysis
D015415:Biomarkers; D008075:Lipoproteins, HDL; D002097:C-Reactive Protein
C-reactive protein; abdominal aortic aneurysm; coronary artery disease; hypertension; monocyte/high-density lipoprotein cholesterol ratio