Cataract Surgery with Primary Lens Implantation in Children with Chronic Uveitis.
OBJECTIVE
To evaluate the evolution of chronic uveitis in children undergoing cataract surgery with primary intraocular lens (IOL) implantation.


METHODS
Twelve children with chronic uveitis underwent cataract surgery with primary posterior chamber intraocular lens (IOL) implantation.


RESULTS
Fourteen eyes were implanted with a foldable hydrophobic acrylic IOL. The mean follow-up was 35.39 months (8.72-69.57). The mean BCDVA before surgery and at the end of follow-up was 1.11 (0.40-2.30; SD: 0.57) and 0.48 (0-3; SD: 0.77; p=0.007) respectively. The mean oral corticosteroids dosage after surgery and at the end of follow-up was 0.80 mg/kg/day (SD: 0.37) and 0.17 mg/kg/day (SD: 0.24; p=0.001) respectively. All patients except one were treated with methotrexate. Four patients (5 eyes) were additionally treated with anti-tumor necrosis factor agent.


CONCLUSIONS
Cataract surgery with primary posterior chamber hydrophobic IOL implantation is possible and leads to a good visual recovery in cases of pediatric chronic uveitis. This surgery requires aggressive anti-inflammatory management with immunosuppressive drugs to control inflammation and reduce the corticosteroids dosage.
a Deptartment of Ophthalmology , DHU Vision and Handicaps , Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.|b Deptartment of Ophthalmology , DHU Vision and Handicaps , Hôpital Pitié-Salpêtrière, Paris , France.
Damien
D
Guindolet
a Deptartment of Ophthalmology , DHU Vision and Handicaps , Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
Pascal
P
Dureau
b Deptartment of Ophthalmology , DHU Vision and Handicaps , Hôpital Pitié-Salpêtrière, Paris , France.
Céline
C
Terrada
a Deptartment of Ophthalmology , DHU Vision and Handicaps , Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
Catherine
C
Edelson
a Deptartment of Ophthalmology , DHU Vision and Handicaps , Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
Amandine
A
Barjol
a Deptartment of Ophthalmology , DHU Vision and Handicaps , Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
Georges
G
Caputo
b Deptartment of Ophthalmology , DHU Vision and Handicaps , Hôpital Pitié-Salpêtrière, Paris , France.
Phuc
P
LeHoang
b Deptartment of Ophthalmology , DHU Vision and Handicaps , Hôpital Pitié-Salpêtrière, Paris , France.
Bahram
B
Bodaghi
D000293:Adolescent; D002386:Cataract / Q000209:etiology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000379:methods*; D008297:Male; D018918:Phacoemulsification; D012189:Retrospective Studies; D014605:Uveitis / Q000150:complications*; D014792:Visual Acuity
Cataract surgery; hydrophilic acrylic intraocular lens; juvenile idiopathic arthritis; lens implantation; uveitis