Antimicrobial Compounds from Eukaryotic Microalgae against Human Pathogens and Diseases in Aquaculture.
The search for novel compounds of marine origin has increased in the last decades for their application in various areas such as pharmaceutical, human or animal nutrition, cosmetics or bioenergy. In this context of blue technology development, microalgae are of particular interest due to their immense biodiversity and their relatively simple growth needs. In this review, we discuss about the promising use of microalgae and microalgal compounds as sources of natural antibiotics against human pathogens but also about their potential to limit microbial infections in aquaculture. An alternative to conventional antibiotics is needed as the microbial resistance to these drugs is increasing in humans and animals. Furthermore, using natural antibiotics for livestock could meet the consumer demand to avoid chemicals in food, would support a sustainable aquaculture and present the advantage of being environmentally friendly. Using natural and renewable microalgal compounds is still in its early days, but considering the important research development and rapid improvement in culture, extraction and purification processes, the valorization of microalgae will surely extend in the future.
FR CNRS 3473 IUML Mer-Molécules-Santé (MMS), Université du Maine, Avenue O. Messiaen, Le Mans 72085, France. Charlotte.Falaise@gmail.com.
Charlotte
C
Falaise
Ifremer, SG2M-LGPMM, Laboratoire de Génétique et de Pathologie des Mollusques Marins, Avenue Mus de Loup, La Tremblade 17390, France. Cyrille.Francois@ifremer.fr.
Cyrille
C
François
Ifremer, SG2M-LGPMM, Laboratoire de Génétique et de Pathologie des Mollusques Marins, Avenue Mus de Loup, La Tremblade 17390, France. Marie.Agnes.Travers@ifremer.fr.
Marie-Agnès
MA
Travers
Ifremer, SG2M-LGPMM, Laboratoire de Génétique et de Pathologie des Mollusques Marins, Avenue Mus de Loup, La Tremblade 17390, France. Benjamin.Morga@ifremer.fr.
Benjamin
B
Morga
Ifremer, SG2M-LGPMM, Laboratoire de Génétique et de Pathologie des Mollusques Marins, Avenue Mus de Loup, La Tremblade 17390, France. Joel.Haure@ifremer.fr.
Joël
J
Haure
Institut des Sciences de la Mer de Rimouski, Université du Québec à Rimouski, 310 des Ursulines, Rimouski, QC G5L 3A1, Canada. Rejean_Tremblay@uqar.ca.
Réjean
R
Tremblay
Institut des Sciences de la Mer de Rimouski, Université du Québec à Rimouski, 310 des Ursulines, Rimouski, QC G5L 3A1, Canada. Francois.Turcotte@uqar.ca.
François
F
Turcotte
UMR CNRS 6283 Institut des Molécules et Matériaux du Mans (IMMM), Université du Maine, Avenue O. Messiaen, Le Mans 72085, France. Pamela.Pasetto@univ-lemans.fr.
Pamela
P
Pasetto
FR CNRS 3473 IUML Mer-Molécules-Santé (MMS), Université du Maine, Avenue O. Messiaen, Le Mans 72085, France. gastineauromain@yahoo.fr.
Romain
R
Gastineau
FR CNRS 3473 IUML Mer-Molécules-Santé (MMS), Université du Maine, Avenue O. Messiaen, Le Mans 72085, France. Yann.Hardivillier@univ-lemans.fr.
Yann
Y
Hardivillier
FR CNRS 3473 IUML Mer-Molécules-Santé (MMS), Université du Maine, Avenue O. Messiaen, Le Mans 72085, France. Vincent.Leignel@univ-lemans.fr.
Vincent
V
Leignel
FR CNRS 3473 IUML Mer-Molécules-Santé (MMS), Université du Maine, Avenue O. Messiaen, Le Mans 72085, France. Jean-Luc.Mouget@univ-lemans.fr.
Jean-Luc
JL
Mouget
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use; D017756:Aquaculture / Q000379:methods*; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D056890:Eukaryota; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D058086:Microalgae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000188:drug therapy; D014777:Virus Diseases / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000998:Antiviral Agents
Haslea; antibacterial; antifungal; antimicrobial; antiviral; biological activity; microalgae; sustainable aquaculture