The Relationship Between Depression and Metabolic Syndrome: Systematic Review and Meta-Analysis Study.
BACKGROUND
Several studies have been conducted on the relationship between depression and metabolic syndrome, which have had conflicting results. The purpose of this study was a meta-analysis of studies that have examined the relationship between these two variables.


METHODS
This meta-analysis systematically reviewed the relationship between depression and metabolic syndrome. Scientific databases including IranMedex, SID, Magiran, Scopus, PubMed, Google Scholar, and Science Direct were searched and 17 articles were extracted from 2000 to 2014. Selected studies data were analyzed using meta-analysis and random effects model. Heterogeneity between the studies was examined using I2. Data were analyzed using STATA software version 12.1.


RESULTS
Seventeen studies were analyzed with a sample size of 31880 people. Analysis by the type of studies showed that the relationship between the two variables in cross-sectional studies (OR = 1.51, CI 95% = 1.36 - 1.68) and cohort studies (OR = 1.6, CI 95% = 1.23 - 2.08) was significant. In general, the heterogeneity test results among the studies was not significant (P for heterogeneity = 0.08, I(2) = 39.8%).


CONCLUSIONS
There is a relationship between depression and metabolic syndrome.
MSc in Nursing, Kurdistan University of Medical Sciences, Sanandaj, IR Iran.
Reza
R
Ghanei Gheshlagh
Department of Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IR Iran.
Naser
N
Parizad
Department of Biostatistics, Prevention of Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, IR Iran.
Kourosh
K
Sayehmiri
Depression; Meta-Analysis; Metabolic Syndrome