Estimating years of life lost from cardiovascular mortality related to air pollution in Guangzhou, China.
Previous studies have mainly used mortality or morbidity as the health outcome to examine the air pollution-health association. Little evidence is available on relationships between air pollutants and years of life lost (YLL). We aimed to estimate the YLL from cardiovascular mortality due to air pollution. Daily data on weather and air pollutants and individual data of all registered deaths for years 2004-2007 were obtained in Guangzhou, China. The generalized additive model was used to assess the YLL associated with 10μg/m3increases in NO2, SO2and PM10. We found that the mean daily YLL was 248, 87.5 and 73.7 for deaths from cardiovascular disease (CVD), stroke and ischemic heart disease (IHD), respectively. A significant linear correlation was observed between air pollution and YLL due to cardiovascular disease. The effects of air pollutants on YLL were immediate and lasted for two days. A 10μg/m3increase above the corresponding threshold of 55.6μg/m3, 40.4μg/m3and 0μg/m3in NO2, PM10and SO2was related to YLL increase of 1.8 (95% CI: 0.8-2.9), 2.8 (1.7-3.8) and 2.6 (1.2-4.0) years at lag 0-1days for CVD, respectively. The estimates of YLL associated with NO2and PM10were higher in men than women. The air pollutants-related YLL was higher among young people and those with low education level, compared to the elderly and those with high education level, respectively. These findings confirmed YLL provides a complementary strategy for assessing the health effect of air pollution. This study underscores the necessity of the reduction of air pollution benefiting public health.
State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China. Electronic address: smart_yjun@163.com.
Jun
J
Yang
State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China. Electronic address: ouchunquan@hotmail.com.
Chun-Quan
CQ
Ou
Intensive Care Unit, Guangdong No. 2 Provincial People's Hospital, Guangzhou 510317, China. Electronic address: yfsong126@126.com.
Yu-Feng
YF
Song
State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China. Electronic address: lylygdsg@163.com.
Li
L
Li
State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China. Electronic address: chenpy99@126.com.
Ping-Yan
PY
Chen
State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. Electronic address: liuqiyong@icdc.cn.
Qi-Yong
QY
Liu
D000367:Age Factors; D000393:Air Pollutants / Q000032:analysis*; D000397:Air Pollution / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality*; D002681:China / Q000453:epidemiology; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008017:Life Expectancy; D008297:Male; D009585:Nitrogen Dioxide / Q000032:analysis; D052638:Particulate Matter / Q000032:analysis; D012737:Sex Factors; D012959:Socioeconomic Factors; D013458:Sulfur Dioxide / Q000032:analysis; D014505:Urban Population
D000393:Air Pollutants; D052638:Particulate Matter; D013458:Sulfur Dioxide; D009585:Nitrogen Dioxide
Air pollutants; Cardiovascular disease; China; Mortality; Years of life lost