Which advises for primary food allergy prevention in normal or high-risk infant?
In the last decades, international guidelines proposed different strategies of complementary foods introduction during weaning to prevent allergy. Avoidance measures, such as late introduction of allergenic foods, failed to show a significant preventive effect towards allergy. Recently, prospective randomized controlled studies suggested that the early introduction of solid foods - rather than the late introduction - could be a strategy to prevent allergic sensitization and food allergy. However, at today clear evidence of effectiveness and safety of early introduction are not yet available to recommend a radical change in the current clinical practice. A realistic advice for the general population could be to begin the weaning at 4-5 months with the progressive introduction of different foods. The advices for introduction of solid foods during weaning should also take in consideration the global development of child to chose the better timing of introduction of foods.
Pediatric Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Giampaolo
G
Ricci
Pediatric Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Francesca
F
Cipriani
D000485:Allergens / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D002986:Clinical Trials as Topic; D004032:Diet; D005512:Food Hypersensitivity / Q000276:immunology*; D059647:Gene-Environment Interaction; D006801:Humans; D007108:Immune Tolerance; D018928:Immunity, Mucosal; D007223:Infant; D007225:Infant Food; D064307:Microbiota; D017410:Practice Guidelines as Topic; D012306:Risk; D014886:Weaning
D000485:Allergens; D001324:Autoantigens
allergy; egg; food; infants; introduction; prevention; weaning