Impact of malnutrition on gastrointestinal surgical patients.
The accurate diagnosis of malnutrition is imperative if we are to impact outcomes in the malnourished. The American Society of Parenteral and Enteral Nutrition (ASPEN) and Academy of Nutrition and Dietetics (AND), in an attempt to address this issue, have provided evidence-based criteria to diagnose malnutrition. The purpose of this study was to validate the ASPEN/AND criteria in a cohort of patients from a single high-volume surgical oncology unit.



Patients undergoing major abdominal surgery from June 2013 to March 2015 were classified by their nutritional status using the ASPEN/AND criteria.



A total of 490 patients were included. Median age was 64 y, a majority were female (50.6%), white (60.2%), underwent elective procedures (77.6%), had a Charlson comorbidity score (CCS) of 3-5 (40.0%), and a Clavien-Dindo complication (CDC) grade of 0-II (81.2%). A total of 93 (19.0%) patients were classified as moderately/severely malnourished. On univariate analysis, malnourished patients were more likely to be older, undergo emergent procedures, and have a CCS >5 (P < 0.05). Malnutrition was also associated with a longer postoperative length of stay (LOS), higher cost, higher in-hospital mortality, more severe complications, and higher readmission rates (P < 0.05). Multivariate analysis reaffirmed the association between malnutrition, LOS (odds ratio [OR] = 1.67), and cost (OR = 2.49), P < 0.05. Complications (OR = 1.35), mortality rates (OR = 3.05), and readmission rates (OR = 1.34) P > 0.05 failed to reach significance.



Malnutrition worsens LOS and cost. Utilization of standardized criteria consistently identifies patients at risk of negative outcomes who may benefit from perioperative nutritional support.
Department of Surgery, East Carolina University, Brody School of Medicine, Division of Surgical Oncology, Greenville, North Carolina.
Catalina
C
Mosquera
Department of Surgery, East Carolina University, Brody School of Medicine, Greenville, North Carolina.
Nicholas J
NJ
Koutlas
Department of Surgery, Vidant Medical Center, Greenville, North Carolina.
Kimberly C
KC
Edwards
Department of Surgery, Vidant Medical Center, Greenville, North Carolina.
Ashley
A
Strickland
Department of Surgery, East Carolina University, Brody School of Medicine, Division of Surgical Oncology, Greenville, North Carolina.
Nasreen A
NA
Vohra
Department of Surgery, East Carolina University, Brody School of Medicine, Division of Surgical Oncology, Greenville, North Carolina.
Emmanuel E
EE
Zervos
Department of Surgery, East Carolina University, Brody School of Medicine, Division of Surgical Oncology, Greenville, North Carolina. Electronic address: fitzgeraldt@ecu.edu.
Timothy L
TL
Fitzgerald
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D013505:Digestive System Surgical Procedures / Q000009:adverse effects* / Q000191:economics / Q000401:mortality; D005260:Female; D017721:Hospital Costs; D006801:Humans; D007902:Length of Stay; D008297:Male; D044342:Malnutrition / Q000150:complications*; D008875:Middle Aged; D009657:North Carolina / Q000453:epidemiology; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality; D012189:Retrospective Studies; D055815:Young Adult
Malnutrition; Nutritional assessment; Preoperative evaluation; Surgery