[Use of thrombelastography to guide posttraumatic hemostatic therapy: More coagulation factor concentrates and less allogenic blood transfusion?]
Viscoelastic technics are used for 10 years and include the ROTEM®and the TEG®. These devices that exploit the viscoelastic properties of the clotting blood, allow a rapid and global analysis of the haemostatic process taking into account all the process interfering with haemostasis such as inflammation. It has been shown that the use of these technics in clinical situations such as trauma, postpartum haemorrhage, gastrointestinal bleeding or cardiac surgery may reduce the need for blood product, the cost and perhaps may improve the outcome of the patients. Thanks to a rapid identification of the underlying coagulation deficit, these technics facilitate decision-making during acute care and help to guide the treatment, particularly with coagulation factor's concentrate.
Service d'anesthésie réanimation, hospices civils de Lyon, centre hospitalier Lyon Sud, chemin du Grande-Revoyet, 69495 Pierre-Bénite cedex, France; Faculté de médecine Lyon Sud, université Claude-Bernard - Lyon 1, 69921 Oullins, France. Electronic address: js-david@univ-lyon1.fr.
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David
Service d'anesthésie réanimation, hospices civils de Lyon, centre hospitalier Lyon Sud, chemin du Grande-Revoyet, 69495 Pierre-Bénite cedex, France; Faculté de médecine Lyon Sud, université Claude-Bernard - Lyon 1, 69921 Oullins, France.
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Imhoff
Pharmacie, hospices civils de Lyon, centre hospitalier Lyon Sud, 69495 Pierre-Bénite cedex, France.
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Parat
Unité d'hémovigilance, hospices civils de Lyon, centre hospitalier Lyon Sud, 69495 Pierre-Bénite cedex, France.
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Augey
Laboratoire d'hémostase, hospices civils de Lyon, centre hospitalier Lyon Sud, 69495 Pierre-Bénite cedex, France.
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Geay-Baillat
Service d'anesthésie réanimation, hospices civils de Lyon, centre hospitalier Lyon Sud, chemin du Grande-Revoyet, 69495 Pierre-Bénite cedex, France.
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Incagnoli
Faculté de médecine Lyon Sud, université Claude-Bernard - Lyon 1, 69921 Oullins, France; Service des urgences, SAMU/SMUR, hospices civils de Lyon, hôpital Édouard-Herriot, 69437 Lyon cedex 03, France.
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Tazarourte
D001779:Blood Coagulation Factors / Q000008:administration & dosage / Q000627:therapeutic use*; D001803:Blood Transfusion; D000066491:Clinical Decision-Making; D016903:Drug Monitoring / Q000379:methods; D005340:Fibrinogen / Q000627:therapeutic use*; D006470:Hemorrhage / Q000097:blood* / Q000188:drug therapy / Q000209:etiology / Q000628:therapy; D006487:Hemostasis / Q000502:physiology*; D006489:Hemostatic Techniques; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D010949:Plasma; D019106:Postoperative Hemorrhage / Q000097:blood / Q000188:drug therapy / Q000209:etiology / Q000628:therapy; D006473:Postpartum Hemorrhage / Q000097:blood / Q000188:drug therapy / Q000209:etiology / Q000628:therapy; D013916:Thrombelastography / Q000295:instrumentation; D014947:Wounds and Injuries / Q000150:complications*
D001779:Blood Coagulation Factors; D006490:Hemostatics; C025667:prothrombin complex concentrates; D005340:Fibrinogen
Coagulation factors; Facteurs de coagulation; Fibrinogen; Fibrinogène; Haemostasis; Hémostase; Thromboelastometry; Thromboélastométrie