Postoperative analgesia with dexmedetomidine in interscalene block. Comparative study.
BACKGROUND
Dexmedetomidine prolongs sensory block of ropivacaine. Our objective was to study whether this extension would produce better postoperative pain control compared to that produced by clonidine in patients undergoing arthroscopic shoulder.


METHODS
Study comparative, longitudinal, controlled, randomized into 3 groups. Control group I: ropivacaine 0.75% clonidine group II: 0.75% ropivacaine plus clonidine 1mg/kg group iiidexmedetomidine: 0.75% ropivacaine more dexmedetomidine 1mg/kg. Interscalene block single dose ultrasound-guided. Sensory and motor blockade, pain intensity, sedation level, heart rate, respiratory rate, blood pressure at 6, 12 and 24hours was measured.


RESULTS
Pain intensity at 6hours in groups I and II moderate to severe pain, mild pain group iii. At 12hours the groups IIand II showed moderate to severe pain by more than 60% of patients, and in group iiionly 10%. At 24hours I and II group 20% of patients they continued to moderate pain.


CONCLUSIONS
The prolonged interscalene block produced by dexmedetomidine provided better postoperative pain control during the first 24hours.
Sección de Anestesiología, Hospital Militar de Especialidades de la Mujer y Neonatología.
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Velázquez-Delgado
División de Anestesiología, Instituto Nacional de Rehabilitación.
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Gaspar-Carrillo
División de Anestesiología, Instituto Nacional de Rehabilitación.
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Peña-Riveron
Servicio de Anestesiología, Hospital Ángeles México, Ciudad de México, México. Electronic address: gisibyg@yahoo.com.mx.
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GE
Mejía-Terrazas
D000293:Adolescent; D058647:Adrenergic alpha-2 Receptor Agonists / Q000008:administration & dosage* / Q000494:pharmacology; D000328:Adult; D000368:Aged; D000577:Amides / Q000008:administration & dosage / Q000494:pharmacology; D000698:Analgesia / Q000379:methods*; D000700:Analgesics / Q000008:administration & dosage* / Q000494:pharmacology; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000494:pharmacology; D001182:Arthroscopy; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology; D020927:Dexmedetomidine / Q000008:administration & dosage* / Q000494:pharmacology; D004357:Drug Synergism; D004558:Electric Stimulation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000187:drug effects; D009407:Nerve Block / Q000379:methods*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies; D000077212:Ropivacaine; D012677:Sensation / Q000187:drug effects; D012782:Shoulder / Q000601:surgery; D016037:Single-Blind Method; D018084:Ultrasonography, Interventional; D055815:Young Adult
D058647:Adrenergic alpha-2 Receptor Agonists; D000577:Amides; D000700:Analgesics; D000779:Anesthetics, Local; D020927:Dexmedetomidine; D000077212:Ropivacaine; D003000:Clonidine
Adjuvants; Adyuvantes; Bloqueo interescalénico; Clonidina; Clonidine; Dexmedetomidina; Dexmedetomidine; Dolor postoperatorio; Interscalene block; Postoperative pain