Increased spatial dimensions of repetitive heat and cold stimuli in older women.
Protocols of temporal summation (TS) of pain typically involve the delivery of brief repetitive noxious pulses of a constant intensity while measuring the perceived intensity of pain after each pulse. The size percept of noxious repetitive stimulation has been poorly characterized. Furthermore, no studies have investigated age differences in TS of cold pain. The current study examined TS of pain intensity and the perceived size of the painful area during repetitive noxious heat and cold pulses in healthy younger (n = 104) and older adults (n = 40). Trials of 10 brief repetitive noxious heat or cold pulses were delivered to the upper extremities. Participants rated the perceived size of the painful area or intensity of pain after each pulse. The magnitude of change for the size percept and intensity for pain were calculated for each trial. The results indicated that older adults experienced greater TS of the size percept of cold stimuli compared with younger adults. Additionally, older women experienced greater TS of the size percept of heat stimuli compared with older men and all younger participants. No overall age or sex differences were found in the TS of pain intensity for cold or heat trials. These results suggest dysfunctional modulation of the spatial percept of the painful stimuli by older adults, and in particular older women, during repetitive noxious thermal pulses.
Department of Kinesiology, School of Physical Education and Tourism Management, Indiana University Purdue University Indianapolis, IN, USA.
Kelly M
KM
Naugle
College of Medicine and Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.
Yenisel
Y
Cruz-Almeida
College of Dentistry and Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.
Roger B
RB
Fillingim
College of Medicine and Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.
Roland
R
Staud
College of Dentistry and Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.
Joseph L
JL
Riley
D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging; D000704:Analysis of Variance; D003080:Cold Temperature; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement; D017288:Pain Threshold / Q000502:physiology*; D010812:Physical Stimulation; D015203:Reproducibility of Results; D012727:Sex Characteristics; D055815:Young Adult