An assessment of key risk factors for surgical site infection in patients undergoing surgery for spinal metastases.
This study aimed to determine the rate of surgical site infection (SSI) in patients undergoing surgery for spinal metastases, and identify key risk factors for SSI among this patient group.



A retrospective case note review was undertaken in adult patients being treated at a single specialist centre for spinal surgery.



There were 152 patients identified for inclusion. Overall SSI rate was 11.2 per 100 patients (9.7 per 100 procedures). An increase in the risk of SSI was observed when surgery involved a greater number of vertebral levels (odds ratio 1.26, p=0.019) when controlling for primary spinal region. Controlling for the number of spinal levels, the odds of SSI increased by a factor of 5.6 (p=0.103) when the primary surgical region was thoracic, as opposed to cervical or lumbar.



In conclusion, surgery associated with multiple vertebral levels for treatment of spinal metastases, particularly of the thoracic spine, is associated with increased risk of SSI.
Greater Manchester Neurosciences Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, UK.|Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, The University of Manchester, Salford Royal NHS Foundation Trust, Salford, UK.
R A
RA
Atkinson
School of Human and Health Sciences, University of Huddersfield, Huddersfield, UK.
J
J
Stephenson
Greater Manchester Neurosciences Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, UK.
A
A
Jones
Greater Manchester Neurosciences Centre, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, UK.
K J
KJ
Ousey
D006801:Humans; D015994:Incidence; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D013125:Spinal Neoplasms / Q000556:secondary / Q000601:surgery*; D013530:Surgical Wound Infection / Q000453:epidemiology*
metastases; spine; surgical site infection; vertebrae; wound