Early outcomes after small incision lenticule extraction and photorefractive keratectomy for correction of high myopia.
We prospectively compared visual and refractive outcomes in patients with high myopia and myopic astigmatism after small-incision lenticule extraction (SMILE) and photorefractive keratetctomy (PRK) with mitomycin C. Sixty-six eyes of 33 patients (mean age, 29.7 ± 5.6 years) were included (SMILE: 34 eyes, PRK 32 eyes). Preoperatively, no significant difference was noted in manifest spherical equivalent (p = 0.326), manifest sphere (p = 0.277), and manifest cylinder (p = 0.625) between both groups. At 1 month, there were significant differences in logMAR uncorrected distance visual acuity, efficacy index and manifest refraction spherical equivalent between SMILE and PRK (p ≤ 0.029). At 6 months, the logMAR corrected distance visual acuity (p = 0.594), logMAR uncorrected visual acuity (p = 0.452), efficacy index (p = 0.215) and safety index was (p = 0.537) was comparable between SMILE and PRK. Significant differences were observed in postoperative manifest spherical equivalent (p = 0.044) and manifest cylinder (p = 0.014) between both groups. At the end of 6 months, 100% of the eyes in SMILE group and 69% of the eyes in PRK group were within ±0.50 D of the attempted cylindrical correction. The postoperative difference vector, magnitude of error and absolute angle of error were significantly smaller after SMILE compared to PRK (p ≤ 0.040) implying a trend towards overcorrection of cylindrical correction following PRK.
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong.|Hong Kong Eye Hospital, Kowloon, Hong Kong.
Tommy C Y
TC
Chan
Department of Mathematics and Statistics, Hang Seng Management College, Hong Kong.
Marco C Y
MC
Yu
Department of Ophthalmology, The University of Hong Kong, Hong Kong.
Alex
A
Ng
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China Hong.
Zheng
Z
Wang
Kong Laser Eye Center, Hong Kong.
George P M
GP
Cheng
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong.|Hong Kong Eye Hospital, Kowloon, Hong Kong.
Vishal
V
Jhanji
D000328:Adult; D001251:Astigmatism / Q000601:surgery*; D005260:Female; D006801:Humans; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D009216:Myopia / Q000601:surgery*; D018903:Photorefractive Keratectomy / Q000379:methods*; D011446:Prospective Studies; D012029:Refraction, Ocular; D000072836:Surgical Wound; D016896:Treatment Outcome; D014792:Visual Acuity