Simulating the epidemiological and economic effects of an African swine fever epidemic in industrialized swine populations.
African swine fever (ASF) is a notifiable infectious disease with a considerable impact on animal health and is currently one of the most important emerging diseases of domestic pigs. ASF was introduced into Georgia in 2007 and subsequently spread to the Russian Federation and several Eastern European countries. Consequently, there is a non-negligible risk of ASF spread towards Western Europe. Therefore it is important to develop tools to improve our understanding of the spread and control of ASF for contingency planning. A stochastic and dynamic spatial spread model (DTU-DADS) was adjusted to simulate the spread of ASF virus between domestic swine herds exemplified by the Danish swine population. ASF was simulated to spread via animal movement, low- or medium-risk contacts and local spread. Each epidemic was initiated in a randomly selected herd - either in a nucleus herd, a sow herd, a randomly selected herd or in multiple herds simultaneously. A sensitivity analysis was conducted on input parameters. Given the inputs and assumptions of the model, epidemics of ASF in Denmark are predicted to be small, affecting about 14 herds in the worst-case scenario. The duration of an epidemic is predicted to vary from 1 to 76days. Substantial economic damages are predicted, with median direct costs and export losses of €12 and €349 million, respectively, when epidemics were initiated in multiple herds. Each infectious herd resulted in 0 to 2 new infected herds varying from 0 to 5 new infected herds, depending on the index herd type.
Section for Epidemiology, National Veterinary Institute, Technical University of Denmark, Copenhagen, Denmark. Electronic address: Tahbh@vet.dtu.dk.
Tariq
T
Halasa
Section for Epidemiology, National Veterinary Institute, Technical University of Denmark, Copenhagen, Denmark.
Anette
A
Bøtner
Danish Veterinary and Food Administration, Ministry of Environment and Food, Glostrup, Denmark.
Sten
S
Mortensen
Danish Veterinary and Food Administration, Ministry of Environment and Food, Glostrup, Denmark.
Hanne
H
Christensen
Section for Epidemiology, National Veterinary Institute, Technical University of Denmark, Copenhagen, Denmark.
Nils
N
Toft
Section for Epidemiology, National Veterinary Institute, Technical University of Denmark, Copenhagen, Denmark.
Anette
A
Boklund
D000357:African Swine Fever / Q000191:economics / Q000453:epidemiology* / Q000821:virology; D000358:African Swine Fever Virus / Q000302:isolation & purification / Q000502:physiology*; D000818:Animals; D003198:Computer Simulation; D003718:Denmark / Q000453:epidemiology; D058872:Epidemics / Q000662:veterinary*; D008962:Models, Theoretical; D034421:Sus scrofa; D013552:Swine
African swine fever; Between herds; Model; Simulation; Spread