Development of an integrated CAD-FEA system for patient-specific design of spinal cages.
Spinal cages are used to create a suitable mechanical environment for interbody fusion in cases of degenerative spinal instability. Due to individual variations in bone structures and pathological conditions, patient-specific cages can provide optimal biomechanical conditions for fusion, strengthening patient recovery. Finite element analysis (FEA) is a valuable tool in the biomechanical evaluation of patient-specific cage designs, but the time- and labor-intensive process of modeling limits its clinical application. In an effort to facilitate the design and analysis of patient-specific spinal cages, an integrated CAD-FEA system (CASCaDeS, comprehensive analytical spinal cage design system) was developed. This system produces a biomechanical-based patient-specific design of spinal cages and is capable of rapid implementation of finite element modeling. By comparison with commercial software, this system was validated and proven to be both accurate and efficient. CASCaDeS can be used to design patient-specific cages with a superior biomechanical performance to commercial spinal cages.
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.
Mingzheng
M
Zhang
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.|b State Key Laboratory of Virtual Reality Technology and Systems , Beihang University , Beijing , P.R. China.
Fang
F
Pu
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.
Liqiang
L
Xu
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.
Linlin
L
Zhang
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.
Hang
H
Liang
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.
Deyu
D
Li
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.
Yu
Y
Wang
a Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education , School of Biological Science and Medical Engineering, Beihang University , Beijing , P.R. China.|b State Key Laboratory of Virtual Reality Technology and Systems , Beihang University , Beijing , P.R. China.
Yubo
Y
Fan
D000328:Adult; D001696:Biomechanical Phenomena; D017076:Computer-Aided Design; D020342:Finite Element Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008159:Lumbar Vertebrae / Q000473:pathology; D066230:Patient-Specific Modeling; D019736:Prostheses and Implants; D011474:Prosthesis Design; D013123:Spinal Fusion; D013314:Stress, Mechanical
CASCaDeS; Interbody fusion; finite element analysis; patient-specific design; spinal cage