[Lithogenic risk in patients from Paraguay with urolithiasis].
The lithogenic risk profile is a graphical representation of metabolic factors and urinary saturation involved in the stone formation with their respective critical values.


OBJECTIVE
To determine the lithogenic risk profile in patients with urolithiasis.


METHODS
Personal data such as anthropometric, history of diseases and family history of urolithiasis were recorded. Different compounds acting as promoters or inhibitors of crystallization were measured in serum and urine samples, and the data obtained were used to calculate urinary saturation using Equil software.


RESULTS
We included 30 men and 43 women with a median age of 45 (34-54) years. Overweight and family history of urolithiasis was reported in 63 and 32% respectively. Crystallization risk was detected in 74% of participants. The most common urinary abnormalities were hypocitraturia in 48% and hypercalciuria in 40%.


CONCLUSIONS
The lithogenic profile revealed urinary saturation compatible with crystallization risk in 74% of the studied patients.
Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay.
Patricia
P
Funes
Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay.
Gloria
G
Echagüe
Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay.
Irene
I
Ruiz
Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay.
Lourdes
L
Rivas
Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay.
Jorge
J
Zenteno
Instituto de Investigaciones en Ciencias de la Salud, San Lorenzo, Paraguay, rmguillenf@gmail.com.
Rosa
R
Guillén
D000328:Adult; D015415:Biomarkers / Q000652:urine*; D002118:Calcium / Q000652:urine; D003460:Crystallization; D005260:Female; D006801:Humans; D008274:Magnesium / Q000652:urine; D008297:Male; D008875:Middle Aged; D010070:Oxalates / Q000652:urine; D010239:Paraguay; D010758:Phosphorus / Q000652:urine; D012307:Risk Factors; D012964:Sodium / Q000652:urine; D014527:Uric Acid / Q000652:urine; D052878:Urolithiasis / Q000209:etiology / Q000652:urine*
D015415:Biomarkers; D010070:Oxalates; D014527:Uric Acid; D010758:Phosphorus; D012964:Sodium; D008274:Magnesium; D002118:Calcium