Non-infected penile prosthesis cultures during revision surgery; comparison between antibiotic coated and non - coated devices.
BACKGROUND
Aim of this study is to investigate bacterial growth on non-infected devices and compare antibiotic-coated and non-coated implants.


METHODS
The charts of 71 patients who underwent revision surgeries for penile prosthesis between 1995 and 2013 were reviewed. Of those, 31 devices were antibiotic-coated prostheses, while 40 of the implants were non-coated. Swab cultures were routinely obtained from corporal, pump or reservoir site during the operation. If a bacterial biofilm was determined on the prosthesis, it was also cultured.


RESULTS
A total of 5 different organisms were cultured from 18 patients. Of them, 4 devices were antibiotic-coated and the other 14 were non-coated devices. Staphylococcus epidermidis was the most common organism, while Staphylococcus hominis, beta hemolitic streptococcus, Escherichia coli and Proteus mirabilis were also cultured. All patients who had positive cultures were treated with appropriate antibiotics for four weeks postoperatively. Median follow-up time was 41 months, ranging between 8 and 82 months. One prosthesis (non-coated) became clinically infected in the follow-up period with a totally different organism. Culture positivity rates of antibiotic-coated and non-coated devices were 13% and 35% respectively and the result was significant (p=0.00254).


CONCLUSIONS
Positive bacterial cultures are present on non-infected penile prostheses at revision surgeries in some of the patients. Antibiotic coated prostheses have much less positive cultures than non-coated devices.
Department of Urology, University of Kocaeli Medical Faculty, Kocaeli, Turkey.
Seyfettin
S
Ciftci
Department of Health School, University of Sakarya, Sakarya, Turkey.
Tijen
T
Nemut
Department of Urology, University of Kocaeli Medical Faculty, Kocaeli, Turkey.
Mustafa Melih
MM
Culha
Department of Urology, University of Kocaeli Medical Faculty, Kocaeli, Turkey.
Hasan
H
Yilmaz
Department of Urology, Derince Research and Training Hospital, Kocaeli, Turkey.
Murat
M
Ustuner
Department of Urology, Karaman State Hospital, Karaman, Turkey.
Ufuk
U
Yavuz
Department of Urology, University of Kocaeli Medical Faculty, Kocaeli, Turkey.
Levend
L
Ozkan
Department of Microbiology, University of Kocaeli Medical Faculty, Kocaeli, Turkey.
Aynur
A
Karadenizli
Department of Urology, Kastamonu Anadolu Hospital, Kastamonu, Turkey.
Sadi
S
Turkan
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002478:Cells, Cultured; D015169:Colony Count, Microbial; D016503:Drug Delivery Systems; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015917:Penile Prosthesis / Q000009:adverse effects / Q000382:microbiology*; D011446:Prospective Studies; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000517:prevention & control*; D012189:Retrospective Studies; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000254:growth & development*; D013997:Time Factors
D000900:Anti-Bacterial Agents
Antibiotic Prophylaxis; Culture; Penile Prosthesis