[A Case of Xp.11.2 Traslocational Renal Cell Carcinoma Diagnosed by Fluorescence in Situ Hybridization (FISH)].
A 72-year-old woman was referred to our hospital with complaints of macro-hematuria. The radiographic evaluation including computed tomography (CT) and magnetic resonance imaging (MRI) suggested it to be renal cell carcinoma (RCC) in her right kidney. She underwent laparoscopic nephrectomy. We diagnosed her with renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion, based on pathological findings and break apart of transcription factor E3 (TFE3)by fluorescence in situ hybridization. She was free of recurrence at 8 months postoperatively.
The Department of Urology, Japanese Red Cross Takayama Hospital.
Koji
K
Iinuma
The Department of Urology, Japanese Red Cross Takayama Hospital.
Keitaro
K
Kojima
The Department of Surgical Pathology, Japanese Red Cross Takayama Hospital.
Kiyohisa
K
Okamoto
The Department of Urology, Japanese Red Cross Takayama Hospital.
Kazuya
K
Yuhara
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000235:genetics*; D041321:Chromosomes, Human, X; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D064847:Multimodal Imaging; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic