Clinical efficacy of certain Unani herbs in knee osteoarthritis: A pretest and post-test evaluation study.
OBJECTIVE
This study was conducted to evaluate the efficacy of preparations of certain Unani herbs on Lequesne Algo-Functional Index of knee osteoarthritis (OA).


METHODS
A prospective, pre- and post test evaluation study was conducted on 20 diagnosed patients of OA recruited from the Nizamia General Hospital, Hyderabad. Internally, a combination (formula) of Unani herbs was administered, which was as follows: 3.5 g powder of Asarun (2 g), Tukhme karafs (2 g), and Filfil daraz (3 g) was administered internally twice daily. Externally, the concoction of Gule baboona (20 g) and Gule tesu (40 g) made in 1 l water was poured over the affected knee, daily once for 40 days. The primary outcome was to assess the efficacy of Unani test drugs with the modified Lequesne Algo-Functional Index for knee OA.


RESULTS
The mean percentage reduction of Lequesne Algo-Functional Index score was 71.09%. The mean and standard deviation was 10.55 (1.70) and 3.05 (2.30) before treatment and after treatment, respectively. The pre- and post test evaluation showed reduction in Lequesne Algo-Functional Index score (P < 0.0001).


CONCLUSIONS
In this study, the Unani treatment module was found to be effective in reducing the severity of disease in patients with osteoarthritis of knees.
Department of Moalajat (General Medicine), HARK Hospital, M.I.J. Unani Medical College, Mumbai, Maharashtra, India.
Asfia
A
Tarannum
Department of Amraze Niswan wa Ilmul Qabalat (Obstetrics and Gynecology), National Institute of Unani Medicine, Bengaluru, Karnataka, India.
Arshiya
A
Sultana
Department of Ilmul Saidla (Pharmacy), National Institute of Unani Medicine, Bengaluru, Karnataka, India.
Khaleeq
K
Ur Rahman
Knee osteoarthritis; Lequesne Algo-Functional Index; Unani medicine; randomized comparative study