Titrated doses are optimal for opioids in pain trials.
Department of Emergency Medicine and Surgery, GH Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris, Paris 75013, France; Sorbonne Universités, UPMC Univ Paris 06, Paris, France. Electronic address: bruno.riou@aphp.fr.
Bruno
B
Riou
Department of Anesthesia and Critical Care, Hôpital de la Croix Rousse, Hospices Civils de Lyon, Lyon, France; Claude Bernard Lyon 1 University, Lyon, France.
Frédéric
F
Aubrun
D000701:Analgesics, Opioid / Q000627:therapeutic use*; D006801:Humans; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement
D000701:Analgesics, Opioid