Palladium(II) Catalyzed Cyclization-Carbonylation-Cyclization Coupling Reaction of (ortho-Alkynyl Phenyl) (Methoxymethyl) Sulfides Using Molecular Oxygen as the Terminal Oxidant.
An efficient Pd(II)/Pd⁰-p-benzoquinone/hydroquinone-CuCl₂/CuCl catalyst system was developed that uses environmentally friendly molecular oxygen as the terminal oxidant to catalyze the cyclization-carbonylation-cyclization coupling reaction (CCC-coupling reaction) of (o-alkynyl phenyl) (methoxymethyl) sulfides.
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. shenrong_927@yahoo.co.jp.
Rong
R
Shen
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. taichi.kusakabe@phar.toho-u.ac.jp.
Taichi
T
Kusakabe
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. 3014004y@nc.toho-u.ac.jp.
Tomofumi
T
Yatsu
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. ykanno@phar.toho-u.ac.jp.
Yuichiro
Y
Kanno
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. keisuke.takahashi@phar.toho-u.ac.jp.
Keisuke
K
Takahashi
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. kiyomitsu.nemoto@phar.toho-u.ac.jp.
Kiyomitsu
K
Nemoto
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan. kkk@phar.toho-u.ac.jp.
Keisuke
K
Kato
D002384:Catalysis; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry*
D013440:Sulfides; D010165:Palladium; D010100:Oxygen
CCC-coupling reaction; bisoxazoline; carbonylation; molecular oxygen; palladium