Invasive Scedosporium sternal osteomyelitis following lung transplant: Cured.
Scedosporium is an important pathogen in cystic fibrosis (CF) and post-transplant but rarely causes invasive infection. Treatment remains challenging, particularly due to inherent resistance to multiple antifungal agents. We present a young man with CF who developed invasive sternal and rib infection 10-months following lung transplant. The infection has been clinically and radiologically cured with extensive surgery and triazole therapy. This case highlights the importance of adjunctive surgery in addition to prolonged triazole treatment to manage invasive Scedosporium infections in immunosuppressed patients.
Lung Transplant Unit, Alfred Hospital, 55 Commercial Road, 3181 Melbourne, Australia.
E J
EJ
Denton
Department of Infectious Diseases, Alfred Hospital and Monash University, 55 Commercial Road, 3181 Melbourne, Australia.
O
O
Smibert
Department of Cardiothoracic Surgery, Alfred Hospital, 55 Commercial Road, 3181 Melbourne, Australia.
J
J
Gooi
Department of Infectious Diseases, Alfred Hospital and Monash University, 55 Commercial Road, 3181 Melbourne, Australia.
C O
CO
Morrissey
Lung Transplant Unit, Alfred Hospital, 55 Commercial Road, 3181 Melbourne, Australia.
G
G
Snell
Department of Cardiothoracic Surgery, Alfred Hospital, 55 Commercial Road, 3181 Melbourne, Australia.
D
D
McGiffin
Lung Transplant Unit, Alfred Hospital, 55 Commercial Road, 3181 Melbourne, Australia.
M
M
Paraskeva
Cystic fibrosis; Posaconazole; Scedosporium; Transplant; Voriconazole