Data on the phosphorylation of p38MAPK and JNK induced by chlorpyrifos in Drosophila melanogaster.
Exposure to organophosphate compounds, such as chlorpyrifos, has been linked to disturbances on cell signaling pathways. Mitogen activated protein kinases (MAPK) are a family of protein kinases involved in a range of cellular processes, including stress response, apoptosis and survival. Therefore, changes in the activation state of these kinases may characterize key mechanisms of toxicity elicited by xenobiotics. Here we report data on the phosphorylation of p38MAPK and JNK, members of the MAPK family, in Drosophila melanogaster exposed to chlorpyrifos, as characterized by western blotting assays.
Oxidative Stress and Cell Signaling Research Group. Universidade Federal do Pampa, Campus São Gabriel, São Gabriel, RS, Brazil.
J E S
JE
Batista
Oxidative Stress and Cell Signaling Research Group. Universidade Federal do Pampa, Campus São Gabriel, São Gabriel, RS, Brazil.
L R
LR
Sousa
Oxidative Stress and Cell Signaling Research Group. Universidade Federal do Pampa, Campus São Gabriel, São Gabriel, RS, Brazil.
I K
IK
Martins
Oxidative Stress and Cell Signaling Research Group. Universidade Federal do Pampa, Campus São Gabriel, São Gabriel, RS, Brazil.
N R
NR
Rodrigues
Oxidative Stress and Cell Signaling Research Group. Universidade Federal do Pampa, Campus São Gabriel, São Gabriel, RS, Brazil.
T
T
Posser
Oxidative Stress and Cell Signaling Research Group. Universidade Federal do Pampa, Campus São Gabriel, São Gabriel, RS, Brazil.
J L
JL
Franco
Biomarkers; Cell signaling; Mechanisms of toxicity; Organophosphate compounds; Stress response