How to open a Ryanodine Receptor.
Ryanodine Receptors are large ion channels responsible for the release of Ca from the Endoplasmic and Sarcoplasmic Reticulum, a prerequisite for muscle contraction. Recent cryo-electron microscopy data have allowed a direct visualization of allosteric motions within these membrane protein giants.
University of British Columbia, Department of Biochemistry and Molecular Biology, 2350 Health Sciences Mall, V6T 1Z3 Vancouver, BC, Canada.
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Van Petegem
D020013:Calcium Signaling; D020285:Cryoelectron Microscopy; D009119:Muscle Contraction; D019837:Ryanodine Receptor Calcium Release Channel; D012519:Sarcoplasmic Reticulum
D019837:Ryanodine Receptor Calcium Release Channel