Imaging comparison of tubular and colloid pancreatic adenocarcinoma arising from intraductal papillary mucinous neoplasm on multidetector CT.
OBJECTIVE
This study aims to compare tubular pancreatic ductal adenocarcinoma (tPDAC) and colloid subtype pancreatic ductal adenocarcinoma (cPDAC) associated with intraductal papillary mucinous neoplasms (IPMNs) on computed tomography.


METHODS
An institutional review board-approved retrospective study included patients with either IPMN tPDAC or cPDAC. Enhancing mural nodules (MN), solid component (SC), main pancreatic duct (MPD) diameter, and abrupt change in MPD caliber were evaluated.


RESULTS
A total of 22 patients with cPDAC and 17 patients with tPDAC showed no significant difference in MPD size. MN and SC were seen in cPDAC/tPDAC in 55%/18% and 9%/53%, respectively. Abrupt change in MPD caliber was seen in cPDAC/tPDAC at 18%/59%.


CONCLUSIONS
cPDAC and tPDAC differ in the frequency of MN, SC, and changes in MPD caliber.
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Department of Radiology, Weill Cornell Medicine, New York, NY 10021.
Joanna G
JG
Escalon
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Scott
S
Gerst
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Matthew
M
Porembka
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Peter J
PJ
Allen
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065. Electronic address: dok@mskcc.org.
Richard K G
RK
Do
D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000000981:diagnostic imaging* / Q000473:pathology; D000231:Adenocarcinoma, Papillary / Q000000981:diagnostic imaging* / Q000473:pathology; D000368:Aged; D021441:Carcinoma, Pancreatic Ductal / Q000000981:diagnostic imaging* / Q000473:pathology; D003102:Colloids; D005260:Female; D006801:Humans; D008297:Male; D061330:Multidetector Computed Tomography; D010183:Pancreatic Ducts / Q000000981:diagnostic imaging / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D012189:Retrospective Studies
D003102:Colloids
Cancer; Ct; IPMN; Pancreas; Pancreatic cyst