Liver acquisition with acceleration volume acquisition gadolinium-enhanced magnetic resonance combined with T2 sequences in the diagnosis of local recurrence of rectal cancer.
To investigate the efficacy of liver acquisition with acceleration volume acquisition (LAVA) gadolinium-enhanced magnetic resonance (MR) sequences and to assess its added accuracy in diagnosing local recurrence (LR) of rectal cancer with conventional T2-weighted fast spin echo (FSE) sequences. Pelvic MRI, including T2-weighted FSE sequences, gadolinium-enhanced sequences of LAVA and T1-weighted FSE with fat suppression, was performed on 225 patients with postoperative rectal cancer. Two readers evaluated the presence of LR according to "T2" (T2 sequences only), "T2 + LAVA-Gad" (LAVA and T2 imaging), and "T2 + T1-fs-Gad" (T1 fat suppression-enhanced sequence with T2 images). To evaluate diagnostic efficiency, imaging quality with LAVA and T1-fs-Gad by subjective scores and the signal intensity (SI) ratio. In the result, the SI ratio of LAVA was significantly higher than that of T1-fs-Gad (p = 0.0001). The diagnostic efficiency of "T2 + LAVA-Gad" was better than that of "T2 + T1-fs-Gad" (p = 0.0016 for Reader 1, p = 0.0001 for Reader 2) and T2 imaging only (p = 0.0001 for Reader 1; p = 0.0001 for Reader 2). Therefore, LAVA gadolinium-enhanced MR increases the accuracy of diagnosis of LR from rectal cancer and could replace conventional T1 gadolinium-enhanced sequences in the postoperative pelvic follow-up of rectal cancer.
Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wuteng
W
Cao
Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Fangqian
F
Li
Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jiaying
J
Gong
Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Dechao
D
Liu
Department of Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yanhong
Y
Deng
Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Liang
L
Kang
Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zhiyang
Z
Zhou
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media / Q000627:therapeutic use; D005260:Female; D005682:Gadolinium / Q000627:therapeutic use*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging*; D055815:Young Adult
D003287:Contrast Media; D005682:Gadolinium
Rectal cancer; liver acquisition with acceleration volume acquisition; local recurrence; magnetic resonance imaging