Antibiotic Methylation: A New Mechanism of Antimicrobial Resistance.
In new research on Mycobacterium tuberculosis, the causative agent of tuberculosis, Warrier and colleagues have discovered a novel mode of bacterial drug resistance, namely antibiotic inactivation via N-methylation.
School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Kerri M
KM
Malone
School of Veterinary Medicine, University College Dublin, Dublin, Ireland; School of Medicine, University College Dublin, Dublin, Ireland; School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland; Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland. Electronic address: stephen.gordon@ucd.ie.
Stephen V
SV
Gordon
D000995:Antitubercular Agents; D024881:Drug Resistance, Bacterial / Q000187:drug effects*; D008745:Methylation; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D014376:Tuberculosis
D000995:Antitubercular Agents
Mycobacterium tuberculosis; TB; anti-TB drugs; antibiotic methylation; drug resistance; methyltransferase