[Comparative study of core needle biopsy and fine needle aspiration cytology in the diagnosis of neck lymph node diseases with contrast-enhanced ultrasound].
OBJECTIVE
To compare the efficacies of core needle biopsy and fine needle aspiration cytology in the diagnosis of neck lymph node diseases with contrast-enhanced ultrasound.


METHODS
A total of 105 patients with enlargement cervical lymph nodes were randomly divided into two groups, 49 in group A and 56 in group B. All patients were firstly examined with contrast-enhanced ultrasound to determine the targeted lymph node and the puncture point. Core needle biopsy was performed in Group A and tissues were fixed by with 10% formaldehyde; Fine needle aspiration cytology was performed in Group B and extracts were smeared and fixed with 95% alcohol.


RESULTS
The success rates of sampling were 100.0% in group A and 96.4% in group B. The positive rates of pathological examinations were 97.9% in group A; and 82.1% in group B, with a significant difference between two groups (χ(2) = 6.97, P<0.05).


CONCLUSIONS
The pathologically positive rates of core needle biopsy is higher than that of fine needle aspiration cytology for the diagnosis of neck lymph node diseases with contrast-enhanced ultrasound.
Department of Ultrasound, Red Cross Hospital of Hangzhou, Hangzhou 310003, China.
W Z
WZ
Zhang
Department of Ultrasound, Red Cross Hospital of Hangzhou, Hangzhou 310003, China.
G Y
GY
Yang
Department of Ultrasound, Red Cross Hospital of Hangzhou, Hangzhou 310003, China.
J P
JP
Xu
Department of Ultrasound, Red Cross Hospital of Hangzhou, Hangzhou 310003, China.
L
L
Zhang
Department of Ultrasound, Red Cross Hospital of Hangzhou, Hangzhou 310003, China.
J
J
Li
Department of Ultrasound, Red Cross Hospital of Hangzhou, Hangzhou 310003, China.
D
D
Zhao
D044963:Biopsy, Fine-Needle; D062005:Biopsy, Large-Core Needle; D003287:Contrast Media; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D009333:Neck
D003287:Contrast Media