The Prevention of Venous Thromboembolism in Surgical Patients.
Patients undergoing surgery are at an increased risk of VTE. Since the early 1990s the prevention of VTE has been dominated by the administration of low-molecular weight heparin during admission. New oral anticoagulants have been extensively researched and have increased in popularity. This chapter reviews why surgical patients are at increased risk of VTE and summaries both the pharmacological and mechanical methods of prophylaxis available.
Academic Surgery Unit, Education and Research Centre, University Hospital of South Manchester NHS Trust, 2nd Floor, Manchester, M23 9LT, UK. vivak.hansrani@manchester.ac.uk.
Vivak
V
Hansrani
Academic Surgery Unit, Education and Research Centre, University Hospital of South Manchester NHS Trust, 2nd Floor, Manchester, M23 9LT, UK.
Mustafa
M
Khanbhai
Academic Surgery Unit, Education and Research Centre, University Hospital of South Manchester NHS Trust, 2nd Floor, Manchester, M23 9LT, UK.
Charles
C
McCollum
D000367:Age Factors; D000925:Anticoagulants / Q000627:therapeutic use*; D003141:Communicable Diseases / Q000503:physiopathology; D000069604:Dabigatran / Q000627:therapeutic use; D003681:Dehydration / Q000503:physiopathology; D000077425:Fondaparinux; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D020249:Hormone Replacement Therapy / Q000009:adverse effects; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology; D009765:Obesity / Q000503:physiopathology; D011134:Polysaccharides / Q000627:therapeutic use; D011322:Primary Prevention; D011655:Pulmonary Embolism / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D012307:Risk Factors; D013514:Surgical Procedures, Operative / Q000009:adverse effects; D054556:Venous Thromboembolism / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D020246:Venous Thrombosis / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*
D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D011134:Polysaccharides; D000069604:Dabigatran; D000077425:Fondaparinux
Anticoagulation; Deep vein thrombosis; Prevention; Pulmonary embolus; Venous thromboembolism