[What is the role of intraoperative radiotherapy in breast cancer treatment?].
Breast-conserving surgery followed by whole breast postoperative irradiation is considered to be the current standard treatment for patients with early stage breast cancer. It allows an excellent local tumour control with 6% of local recurrence. Over the last years, partial breast radiotherapy has been developed to reduce treatment volume and duration. Intraoperative radiotherapy is one of the techniques. It offers an excellent delineation of the tumour bed and high normal tissue sparing. This purpose of this review is to describe the different intraoperative radiotherapy techniques available, to assess their potential clinical efficiency and tolerance, the recommendations for new practice with a selected population of patients and for future research.
Département de radiothérapie, institut de cancérologie de l'Ouest, boulevard Jacques-Monod, 44085 Saint-Herblain, France. Electronic address: maud.aumont@ico.unicancer.fr.
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Aumont
D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local; D018714:Radiotherapy, Adjuvant
Breast cancer; Cancer du sein; Intraoperative radiotherapy; Local recurrence; Radiothérapie externe; Radiothérapie peropératoire; Rechute locale; Toxicity; Toxicité; Whole breast postoperative radiotherapy