QuEChERS-based method for the determination of carbamate residues in aromatic herbs by UHPLC-MS/MS.
A new reliable, fast and highly sensitive method based on ultra-high performance liquid chromatography tandem mass spectrometry has been developed and validated for the determination of 28 carbamates in aromatic herbs. A modified QuEChERS-based method was optimized for the extraction of carbamate residues from a wide variety of fresh herbal products. The proposed method allowed recoveries higher than 72%, achieving quantification limits of 2μgkg(-1), therefore below maximum residue limits established for this type of samples. The combination of QuEChERS with UHPLC-MS/MS introduces a high-throughput methodology for the monitoring of these residues in this type of matrices scarcely explored. The analysis of the real samples revealed that several samples sold in the European Union and in the North West region of Cameroon contain pesticides in concentrations below the maximum residue limits.
Dept. of Biochemistry, Faculty of Science, University of Bamenda, PO Box 39 Bambili, Cameroon.
Edouard Akono
EA
Nantia
Dept. of Analytical Chemistry, Faculty of Sciences, University of Granada, Av. Fuentenueva s/n, 18071 Granada, Spain.
David
D
Moreno-González
Dept. of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, PO Box 63, Buea, Cameroon.
Faustin P T
FP
Manfo
Dept. of Analytical Chemistry, Faculty of Sciences, University of Granada, Av. Fuentenueva s/n, 18071 Granada, Spain.
Laura
L
Gámiz-Gracia
Dept. of Analytical Chemistry, Faculty of Sciences, University of Granada, Av. Fuentenueva s/n, 18071 Granada, Spain. Electronic address: amgarcia@ugr.es.
Ana M
AM
García-Campaña
D002219:Carbamates / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D010575:Pesticides / Q000032:analysis; D017365:Spices / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*
D002219:Carbamates; D010575:Pesticides
Aromatic herbs; Carbamates; QuEChERS; UHPLC-MS/MS