Hemophagocytosis in the Acute Phase of Fatal Kawasaki Disease in a 4 Month-Old Girl.
BACKGROUND
Kawasaki disease is a systemic vasculitis predominately affecting coronary arteries. Hemophagocytic lymphohistiocytosis can complicate the course of Kawasaki disease. Rare cases of secondary hemophagocytic lymphohistiocytosis occurring during the acute phase of Kawasaki disease have been reported.


METHODS
We report here a 4 month-old girl with diffuse coronary ectasia and secondary hemophagocytic lymphohistiocytosis occurring during the acute phase of incomplete Kawasaki disease.


CONCLUSIONS
Due to the large overlap in clinical symptoms, the presence of atypical findings for Kawasaki disease should suggest the possible diagnosis of hemophagocytic lymphohistiocytosis in these patients.
Department of Pediatric Cardiology, Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey.
Vehbi
V
Doğan
Department of Pediatrics, Gaziosmanpaşa University School of Medicine, Tokat, Turkey.
Erhan
E
Karaaslan
Department of Pediatrics, Gaziosmanpaşa University School of Medicine, Tokat, Turkey.
Samet
S
Özer
Department of Pediatrics, Gaziosmanpaşa University School of Medicine, Tokat, Turkey.
Rüveyda
R
Gümüşer
Department of Pediatrics, Gaziosmanpaşa University School of Medicine, Tokat, Turkey.
Resul
R
Yılmaz
Coronary artery dilatation; Kawasaki disease; hemophagocytic lymphohistiocytosis; macrophage activation syndrome