Current Scenario of Prevalence of Vitamin D Deficiency in Ostensibly Healthy Indian Population: A Hospital Based Retrospective Study.
25-hydroxy vitamin D [25(OH) vit D] deficiency is a serious public health problem, particularly in the Indian sub-continent. The objective of the present study was to study the prevalence of 25(OH) vit D in different age groups. The data of 25(OH) vit D assay of 26,346 ostensibly healthy individuals, enrolled under executive health checkup at Medanta The Medicity, Gurgaon, over a period of 3 years, were extracted from the hospital information system and reviewed extensively. 25(OH) vit D deficiency (VDD) was defined as 25(OH) vit D < 20 ng/ml, insufficiency (VDI) as 25(OH) vit D between 20 and 40 ng/ml and 25(OH) vit D sufficiency (VDS) as 25(OH) D > 40 ng/mL. 25(OH) vit D deficiency (VDD + VDI) was observed in 93 % of the subject population. Maximum number of the subjects belonged to the age group of 41-60 years. 59 % had frank 25(OH) vit D deficiency when cut off level was <20 ng/mL. Mean value of 25(OH) vit D in our subjects was 21.4 ± 14.4 ng/mL. Significant difference in 25(OH) vit D level was observed in between male and female subjects. Simultaneously 25(OH) vit D levels were significantly lower in the patient visited hospital in winter-spring season than the summer-autumn season (p > 0.001). Our study demonstrates a high prevalence of 25(OH) vit D deficiency in an ostensibly healthy Indian population. There is a need for redefining our reference ranges according to our population and extensively improving the status of vitamin D.
Department of Clinical Biochemistry-Lab Medicine, Medanta The Medicity, Gurgaon, Haryana India.
Kirtikar
K
Shukla
Department of Clinical Biochemistry-Lab Medicine, Medanta The Medicity, Gurgaon, Haryana India.
Shikha
S
Sharma
Department of Clinical Biochemistry-Lab Medicine, Medanta The Medicity, Gurgaon, Haryana India.
Aditi
A
Gupta
Department of Clinical Biochemistry-Lab Medicine, Medanta The Medicity, Gurgaon, Haryana India.
Arun
A
Raizada
Department of Clinical Biochemistry-Lab Medicine, Medanta The Medicity, Gurgaon, Haryana India.
Kamini
K
Vinayak
25-hydroxy vitamin D; Nutrient; Ostensibly healthy Indian; Prevalence; Vitamin D deficiency