Carbazole-Substituted Iridium Complex as a Solid State Emitter for Two-Photon Intravital Imaging.
A tris-cyclometalated iridium complex that bears two ligands functionalized by peripheral carbazole groups combines an intense solid state emission and a significant two-photon absorption cross section in the near-infrared. After incorporation into a physiological micellar suspension, it can be used for the intravital two-photon fluorescence microscopy of cerebral vasculature.
Institut Lavoisier de Versailles, UMR 8180 CNRS, Université de Versailles Saint-Quentin en Yvelines , 45 avenue des Etats-Unis, 78035 Cedex Versailles, France.
Marc
M
Lepeltier
Univ. Grenoble Alpes , Grenoble Institut des Neurosciences, GIN, Inserm, U1216, F0-38000 Grenoble, France.
Florence
F
Appaix
Laboratoire de Chimie, ENS de Lyon, CNRS UMR 5182, Université Claude Bernard, Université de Lyon , F69342 Lyon, France.
Yuan Yuan
YY
Liao
Aix-Marseille Université , CNRS, Institut de Chimie Radicalaire ICR, UMR 7273, F-13397 Marseille, France.
Frédéric
F
Dumur
Institut Lavoisier de Versailles, UMR 8180 CNRS, Université de Versailles Saint-Quentin en Yvelines , 45 avenue des Etats-Unis, 78035 Cedex Versailles, France.
Jérôme
J
Marrot
Laboratoire de Chimie, ENS de Lyon, CNRS UMR 5182, Université Claude Bernard, Université de Lyon , F69342 Lyon, France.
Tangui
T
Le Bahers
Laboratoire de Chimie, ENS de Lyon, CNRS UMR 5182, Université Claude Bernard, Université de Lyon , F69342 Lyon, France.
Chantal
C
Andraud
Laboratoire de Chimie, ENS de Lyon, CNRS UMR 5182, Université Claude Bernard, Université de Lyon , F69342 Lyon, France.
Cyrille
C
Monnereau
D000818:Animals; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging; D002227:Carbazoles / Q000138:chemical synthesis / Q000737:chemistry*; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D007259:Infrared Rays; D000069416:Intravital Microscopy; D007495:Iridium / Q000737:chemistry / Q000528:radiation effects*; D051379:Mice; D017785:Photons
D002227:Carbazoles; D056831:Coordination Complexes; D005456:Fluorescent Dyes; D007495:Iridium