Comparison of left ventricular ejection fraction values obtained using invasive contrast left ventriculography, two-dimensional echocardiography, and gated single-photon emission computed tomography.
OBJECTIVE
Left ventricular ejection fraction can be measured by a variety of invasive and non-invasive cardiac techniques. This study assesses the relation of three diagnostic modalities to each other in the measurement of left ventricular ejection fraction: invasive contrast left ventriculography, two-dimensional echocardiography, and quantitative gated single-photon emission computed tomography.


METHODS
Retrospective chart review was conducted on 58 patients hospitalized with chest pain, who underwent left ventricular ejection fraction evaluation using each of the aforementioned modalities within a 3-month period not interrupted by myocardial infarction or revascularization.


RESULTS
The mean left ventricular ejection fraction values were as follows: invasive contrast left ventriculography (0.44±0.15), two-dimensional echocardiography (0.46±0.13), and gated single-photon emission computed tomography (0.37±0.10). Correlations coefficients and associated p values were as follows: invasive contrast left ventriculography versus two-dimensional echocardiography (r=0.69, p<0.001), invasive contrast left ventriculography versus gated single-photon emission computed tomography (r=0.80, p<0.0001), and gated single-photon emission computed tomography versus two-dimensional echocardiography (r=0.69, p<0.001).


CONCLUSIONS
Our results indicate that strong positive correlations exist among the three techniques studied.
Division of Cardiovascular Medicine, University of Missouri, Columbia, MO, USA; The Harry S Truman Memorial Veterans Hospital, Columbia, MO, USA.
Nadish
N
Garg
Division of Cardiovascular Medicine, University of Missouri, Columbia, MO, USA; The Harry S Truman Memorial Veterans Hospital, Columbia, MO, USA.
Thomas
T
Dresser
Division of Cardiovascular Medicine, University of Missouri, Columbia, MO, USA; The Harry S Truman Memorial Veterans Hospital, Columbia, MO, USA.
Kul
K
Aggarwal
Division of Cardiovascular Medicine, University of Missouri, Columbia, MO, USA; The Harry S Truman Memorial Veterans Hospital, Columbia, MO, USA.
Vishal
V
Gupta
Division of Cardiovascular Medicine, University of Missouri, Columbia, MO, USA; The Harry S Truman Memorial Veterans Hospital, Columbia, MO, USA.
Mayank K
MK
Mittal
Division of Cardiovascular Medicine, University of Missouri, Columbia, MO, USA; The Harry S Truman Memorial Veterans Hospital, Columbia, MO, USA.
Martin A
MA
Alpert
Cardiovascular; contrast left ventriculography; echocardiography; left ventricular ejection fraction; quantitative gated single-photon emission computed tomography; radiology