Q&A: Gordon Mills on Neomorphs in Cancer.
Gordon Mills, MD, PhD, chair of systems biology at The University of Texas MD Anderson Cancer Center in Houston, discusses a third category of genomic aberrations besides oncogene activation or tumor suppressor inactivation: neomorphs, or mutations that rewire cellular signaling in unexpected ways, with important functional consequences.
D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D015398:Signal Transduction