Genomic signatures of sex-biased demography: progress and prospects.
Sex-biased demographic events have played a crucial role in shaping human history. Many of these processes affect genetic variation and can therefore leave detectable signatures in the genome because autosomal, X-linked, Y-linked, and mitochondrial DNA inheritance differ between sexes. Here, we discuss how sex-biased processes shape patterns of genetic diversity across the genome, review recent genomic evidence for sex-biased demography in modern human populations, and suggest directions for future research.
School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA. Electronic address: Timothy.h.webster@asu.edu.
Timothy H
TH
Webster
School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA; Center for Evolution and Medicine, The Biodesign Institute at Arizona State University, Tempe, AZ 85287, USA. Electronic address: Melissa.wilsonsayres@asu.edu.
Melissa A
MA
Wilson Sayres
D004272:DNA, Mitochondrial / Q000235:genetics*; D003710:Demography; D005260:Female; D014644:Genetic Variation; D005828:Genetics, Population; D015894:Genome, Human / Q000235:genetics*; D023281:Genomics; D006801:Humans; D008297:Male
D004272:DNA, Mitochondrial