Artificial Nose Technology: Status and Prospects in Diagnostics.
Biomimetic crossreactive sensor arrays have been used to detect and analyze a wide variety of vapor and liquid components in applications such as food science, public health and safety, and diagnostics. As technology has advanced over the past three decades, these systems have become selective, sensitive, and affordable. Currently, the need for noninvasive and accurate devices for early disease diagnosis remains a challenge. This Opinion article provides an overview of the various types of biomimetic crossreactive sensor arrays (also referred to as electronic noses or tongues in the literature), their current use and future directions, and an outlook for future technological development.
Department of Bioengineering and Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA.
Jessica E
JE
Fitzgerald
Harvard Medical School, Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital and Harvard Medical School, 1 Bowdoin Square, Boston, MA 02114, USA.
Eric T H
ETH
Bui
Harvard Medical School, Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital and Harvard Medical School, 1 Bowdoin Square, Boston, MA 02114, USA.
Naomi M
NM
Simon
Department of Bioengineering and Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115-5000, USA. Electronic address: h.fenniri@neu.edu.
Hicham
H
Fenniri
D040761:Biomimetic Materials; D015374:Biosensing Techniques / Q000295:instrumentation*; D001944:Breath Tests / Q000295:instrumentation* / Q000379:methods; D003217:Conductometry / Q000295:instrumentation; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D062609:Electronic Nose; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005740:Gases / Q000032:analysis*; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation; D019095:Point-of-Care Systems
D005740:Gases
barcoded resins; bioanalytical chemistry; diagnostics; electronic nose; electronic tongue; sensors