Vertebral artery and osseous anomalies characteristic at the craniocervical junction diagnosed by CT and 3D CT angiography in normal Czech population: analysis of 511 consecutive patients.
There are numerous indications for stabilization using instrumentation of the upper cervical spine. This area is comprised of sophisticated anatomy. There is no study describing bony and vascular anomalies of this area in the middle European population. The main aim of this study was to investigate prevalence of any vertebral artery (VA) variations and osseous anomalies in the region of the craniocervical junction in a large sample of Czech patients based on three-dimensional computed tomographic angiography (3D CTA). The VA has a variable course through C2 before it passes above its groove on the posterior arch of C1. The artery can course more medially, more posteriorly or more superiorly, thus limiting the diameter of the bony elements used as landmarks for the safe insertion of metalwork. This is known as a high-riding VA (HRVA). The VA was considered HRVA in this study if the thickness of the C2 isthmus was less than 5 mm and/or the C2 internal height was less than 2 mm and/or the width of the C2 pedicle was less than 4 mm. The prevalence of ponticulus posticus (PP) was also identified. Following the VA variations in the V3 segment of the artery were persistent first intersegmental artery (FIA), fenestration (FEN) of the VA, and the posterior inferior cerebellar artery (PICA) branch originating from the C1/2 part of VA. Records of 511 patients from our institution were analyzed. The mean age of the patients was 63.6 years. One hundred and twenty-three (24.1 %) patients were identified to have HRVA, 30 (6 %) present on both sides. The age of patient over 70 years and female sex were found to be significant risk factors for HRVA presence. The prevalence of a nearby PICA branch was 4 %, FIA was 0.4 %, and FEN was 0.2 %. The presence of PP was identified in 14.3 % of patients. The HRVA and PP are common anomalies in the Czech population, and routine preoperative high-resolution CT evaluation is mandatory to prevent the VA injury when C1-C2 instrumentation is planned. The female sex and age over 70 years were found to be the most important factors for HRVA presence. The FIA and the FEN VA were rare in our study contrary to reports published from Asia, showing as many as a 10 % the VA presence over the starting point for C1 lateral screw. On the basis of the infrequent occurrence of these anomalies, we do not recommend routine CT angiography when upper cervical spine instrumentation in the normal population is planned.
Department of Neurosurgery and Neurooncology, First Medical Faculty, Military University Hospital and Charles University, U Vojenské Nemocnice 1200, 169 02, Prague 6, Czech Republic.
P
P
Vaněk
Department of Neurosurgery and Neurooncology, First Medical Faculty, Military University Hospital and Charles University, U Vojenské Nemocnice 1200, 169 02, Prague 6, Czech Republic. ondrej.bradac@uvn.cz.
Ondřej
O
Bradáč
Department of Neurosurgery, Royal Hallamshire Hospital, Sheffield, UK.
P
P
de Lacy
Department of Anatomy and Biomechanics, Faculty of Physical education and Sport, Charles University, Prague, Czech Republic.
R
R
Konopková
Department of Neuroradiology, Military University Hospital, Prague, Czech Republic.
J
J
Lacman
Department of Neurosurgery and Neurooncology, First Medical Faculty, Military University Hospital and Charles University, U Vojenské Nemocnice 1200, 169 02, Prague 6, Czech Republic.
V
V
Beneš
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D001270:Cervical Atlas / Q000000981:diagnostic imaging* / Q000601:surgery; D000072226:Computed Tomography Angiography; D018153:Czech Republic; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D014711:Vertebral Artery / Q000000981:diagnostic imaging* / Q000601:surgery; D055815:Young Adult
C2 vertebra; High-riding vertebral artery; Ponticulus posticus; Surgical anatomy; Vascular anomaly