Lesões vesiculares e prurido intenso em paciente com sífilis secundária:manifestação clínica atípica.
Syphilis is an infectious disease with mucocutaneous lesions that are characteristic of their stage (primary, secondary, or tertiary). These are not always typical and may have other morphologies and unusual symptoms, making diagnosis difficult. The report herein is of a healthy woman with vesicular lesions associated with intense itching.  The diagnosis of secondary syphilis was confirmed with VDRL 1/512 and FTA Abs positive.  Histopathology showed spongiosis in the epidermis and infiltrated lymphocytes and plasma cell in the dermis.  Clinical improvement occurred after the first dose of benzathine penicillin. In the literature, few cases of vesicular lesions in syphilis have been found and itching is mentioned as uncharacteristic . Histology showing spongiosis is also unusual.
Residente de Dermatologia do Hospital Universitário Antônio Pedro/UFF, Niterói - RJ.
Roberta
R
Duarte Bezerra Pinto
Thiago
T
Rubim Bellott Batista Nascimento
Jhéssica
J
Pacheco Bicalho de Andrade
Fernanda
F
Policarpo
Rogério
R
Ribeiro Estrella
Enoi
E
Guedes Vilar
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005148:Facial Dermatoses / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006229:Hand Dermatoses / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D011537:Pruritus; D012867:Skin / Q000473:pathology*; D013587:Syphilis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D055815:Young Adult
D000900:Anti-Bacterial Agents; D010401:Penicillin G Benzathine