Screening Tool for Older Persons' Appropriate Prescriptions for Japanese: Report of the Japan Geriatrics Society Working Group on "Guidelines for medical treatment and its safety in the elderly".
In 2005, the Japan Geriatrics Society published a list of potentially inappropriate medication that was an extract from the "Guidelines for medical treatment and its safety in the elderly 2005." The 2005 guidelines are due for a revision, and a new comprehensive list of potentially inappropriate medications is required.



A total of 15 diseases, conditions and special areas related to their clinical care were selected. We originated clinical questions and keywords for these 15 areas, carried out a systematic review using these search criteria, and formulated guidelines applying the Grading of Recommendations Assessment, Development and Evaluation system advocated by Minds2014. If we did not find good evidence despite the drug being clinically important, we looked for evidence of efficacy and for disease-specific guidelines, and incorporated them into our guidelines.



We selected 2098 articles (140 articles per area), and extracted another 186 articles through a manual search. We further added guidelines based on disease entity and made two lists, one of "drugs to be prescribed with special caution" and the other of "drugs to consider starting," primarily considering individuals aged 75 years or older or those who are frail or in need of special care.



New lists of potentially inappropriate medications and potential prescribing omissions called "Screening Tool for Older Person's Appropriate Prescriptions for Japanese" were constructed. We anticipate that future studies will highlight more evidence regarding the safety of high-quality drugs, further improving the provision of appropriate medical care for the elderly. Geriatr Gerontol Int 2016: 16: 983-1001.
Department of Geriatric Medicine, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
Taro
T
Kojima
Graduate School of Comprehensive Human Sciences, Faculty of Health and Sports Sciences, University of Tsukuba, Tokyo, Japan.
Katsuyoshi
K
Mizukami
Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan.
Naoki
N
Tomita
Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan.
Hiroyuki
H
Arai
Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan.|Division of Geriatric Pharmacotherapy, Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan.
Takashi
T
Ohrui
Department of Geriatric Medicine, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.|General Education Center, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
Masato
M
Eto
Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Yasushi
Y
Takeya
Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.|Department of Nephrology, Osaka University Graduate School of Medicine, Osaka, Japan.
Yoshitaka
Y
Isaka
Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Hiromi
H
Rakugi
Center for Health Check-up and Preventive Medicine, Kanto Central Hospital, Tokyo, Japan.
Noriko
N
Sudo
National Center for Geriatrics and Gerontology, Aichi, Japan.
Hidenori
H
Arai
Department of Urology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hiroaki
H
Aoki
Department of Urology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shigeo
S
Horie
Department of Geriatric Medicine, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
Shinya
0000-0001-5762-4066
S
Ishii
Ishinomaki-Ogatsu Municipal Clinic, Miyagi, Japan.
Koh
K
Iwasaki
Department of Education and Support for Regional Medicine, Department of Kampo Medicine, Tohoku University Hospital, Miyagi, Japan.
Shin
S
Takayama
Centre for Community Liaison and Patient Consultations, Nagoya University Hospital, Aichi, Japan.
Yusuke
Y
Suzuki
Department of Geriatric Medicine, Kyorin University School of Medicine, Tokyo, Japan.
Toshifumi
T
Matsui
Department of Pharmacy, National Center for Geriatrics and Gerontology, Aichi, Japan.
Fumihiro
F
Mizokami
Department of Pharmacy, National Center for Geriatrics and Gerontology, Aichi, Japan.
Katsunori
K
Furuta
Department of Geriatrics and Gerontology, Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan.
Kenji
K
Toba
Department of Geriatric Medicine, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
Masahiro
M
Akishita
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D005260:Female; D005853:Geriatrics / Q000592:standards*; D006801:Humans; D057970:Inappropriate Prescribing / Q000009:adverse effects / Q000706:statistics & numerical data*; D007564:Japan; D008297:Male; D008403:Mass Screening / Q000592:standards; D061214:Patient Safety; D000067561:Potentially Inappropriate Medication List / Q000592:standards*; D017410:Practice Guidelines as Topic / Q000592:standards*; D012955:Societies, Medical / Q000592:standards