A life-threatening duodenal ulcer hemorrhage due to previously unknown primary hyperparathyroidism.
Peptic ulcer bleeding due to primary hyperparathyroidism is extremely rare. We report a case of a 42-year-old male with life-threatening acute upper gastrointestinal bleeding secondary to a duodenal ulcer and a history of kidney stones. Gastroscopic therapy, Billroth II gastrointestinal anastomosis and angiographic embolization were sequentially conducted to arrest the hemorrhage. A complete investigative work-up revealed that the duodenal ulcer bleeding was due to primary hyperparathyroidism coexisting with a parathyroid adenoma. Following this event, the patient developed a severe abdominal cavity infection and sepsis. An elective parathyroidectomy was performed, and the histology was confirmed to be a typical parathyroid adenoma. Postoperatively, the patient's calcium and parathyroid levels were normalized. Attention should be paid to patients with an upper gastrointestinal ulcer, especially when it is accompanied by kidney stones.
Department of General Intensive Care Unit of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Dan
D
Xie
Department of General Surgery of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Kunpeng
K
Hu
Department of General Intensive Care Unit of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Ying
Y
Xian
Department of General Intensive Care Unit of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Ying
Y
Wang
Department of General Intensive Care Unit of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Xiaofeng
X
Yuan
Department of General Intensive Care Unit of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Mingliang
M
Li
Department of General Intensive Care Unit of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Xiaogang
X
Bi
Department of General Intensive Care Unit of Lingnan Hospital, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China kxz6210@126.com.
Kouxing
K
Zhang
hypercalcemia; peptic ulcer hemorrhage; primary hyperparathyroidism