Asymmetrical behaviour of disappearance of reticular pseudodrusen in both eyes during long-term follow-up with spectral domain optical coherence tomography.
OBJECTIVE
To describe asymmetrical disappearance of reticular pseudodrusen (RPD) in patients with age-related macular degeneration (AMD).


METHODS
SDOCTs and infrared images of four patients with RPD were retrospectively collected and evaluated during long-term follow-up of up to 47 months (range 35-47 months).


RESULTS
Unilateral fading of RPD was detected on SDOCTs and infrared images in eyes with and without choroidal neovascularisation (CNV) and intravitreal injections. Presence of RPD in the fellow eyes remained stable in three cases, in one case very few RPD newly developed. Three of the four cases demonstrated unilateral outer retinal atrophy following regression of RPD.


CONCLUSIONS
This report highlights that RPD may almost completely disappear after occurrence and treatment of CNV in neovascular AMD, but also in dry AMD without any treatment and that this phenomenon may be unilateral.
Cologne Image Reading Center, Department of Ophthalmology, University Hospital of Cologne, Germany.
Tina
T
Schick
Cologne Image Reading Center, Department of Ophthalmology, University Hospital of Cologne, Germany.
Lebriz
L
Ersoy
Cologne Image Reading Center, Department of Ophthalmology, University Hospital of Cologne, Germany.
Bernd
B
Kirchhof
Cologne Image Reading Center, Department of Ophthalmology, University Hospital of Cologne, Germany.
Sandra
S
Liakopoulos
age-related macular degeneration; disappearance; reticular pseudodrusen; spectral domain optical coherence tomography