Novel dextran derivatives with unconventional structure formed in an efficient one-pot reaction.
An efficient one-pot synthesis of new dextran derivatives is described. The functional groups of β-alanine, i.e., the carboxyl- and amine group, are converted independently in one-step by iminium chloride to form products with a single substituent. The dextran N-[(dimethylamino)methylene]-β-alanine ester is formed selectively. The structure of the resulting polymers is unambiguously determined by means of NMR- and FTIR-spectroscopy and elemental analysis.
Center of Excellence for Polysaccharide Research, Institute of Organic Chemistry and Macromolecular Chemistry, Friedrich Schiller University of Jena, Humboldtstraße 10, D-07743, Jena, Germany.
Konrad
K
Hotzel
Center of Excellence for Polysaccharide Research, Institute of Organic Chemistry and Macromolecular Chemistry, Friedrich Schiller University of Jena, Humboldtstraße 10, D-07743, Jena, Germany. Electronic address: thomas.heinze@uni-jena.de.
Thomas
T
Heinze
D002712:Chlorides / Q000737:chemistry; D003911:Dextrans / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
D002712:Chlorides; D003911:Dextrans
Dextran; Dextran ester; Formamidine; Iminium chloride; One-pot synthesis; β-alanine