Nanoparticles for Tendon Healing and Regeneration: Literature Review.
Tendon injuries are commonly met in the emergency department. Unfortunately, tendon tissue has limited regeneration potential and usually the consequent formation of scar tissue causes inferior mechanical properties. Nanoparticles could be used in different way to improve tendon healing and regeneration, ranging from scaffolds manufacturing (increasing the strength and endurance or anti-adhesions, anti-microbial, and anti-inflammatory properties) to gene therapy. This paper aims to summarize the most relevant studies showing the potential application of nanoparticles for tendon tissue regeneration.
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Paolo D
PD
Parchi
Lowy Cancer Research Centre, Children's Cancer Institute Australia, UNSW AustraliaSydney, NSW, Australia; Australian Centre for NanoMedicine, UNSW AustraliaSydney, NSW, Australia.
Orazio
O
Vittorio
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Lorenzo
L
Andreani
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Pietro
P
Battistini
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Nicola
N
Piolanti
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Stefano
S
Marchetti
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Andrea
A
Poggetti
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Michele
M
Lisanti
gold nanoparticles; nanoparticles; scaffold; silver nanoparticles; tendon injuries