[Definition of accurate planning target volume margins for esophageal cancer radiotherapy].
More than 4000 cases of esophagus neoplasms are diagnosed every year in France. Radiotherapy, which can be delivered in preoperative or exclusive with a concomitant chemotherapy, plays a central role in treatment of esophagus cancer. Even if efficacy of radiotherapy no longer has to be proved, the prognosis of esophagus cancer remains unfortunately poor with a high recurrence rate. Toxicity of esophageal radiotherapy is correlated with the irradiation volume, and limits dose escalation and local control. Esophagus is a deep thoracic organ, which undergoes cardiac and respiratory motion, making the radiotherapy delivery more difficult and increasing the planning target volume margins. Definition of accurate planning target volume margins, taking into account the esophagus' intrafraction motion and set up margins is very important to be sure to cover the clinical target volume and restrains acute and late radiotoxicity. In this article, based on a review of the literature, we propose planning target volume margins adapted to esophageal radiotherapy.
Service de radiothérapie, centre François-Baclesse, avenue du General-Harris, 14000 Caen, France. Electronic address: paul.lesueur89@gmail.com.
P
P
Lesueur
Service de radiothérapie, institut Jean-Godinot, rue du Général-Koenig, 51100 Reims, France.
S
S
Servagi-Vernat
D004938:Esophageal Neoplasms / Q000532:radiotherapy*; D004947:Esophagus / Q000502:physiology; D006801:Humans; D009068:Movement / Q000502:physiology; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal; D061089:Radiotherapy, Image-Guided; D012119:Respiration
Cancer de l’œsophage; Esophagus neoplasms; Internal target volume; Marges; Margins; Planning target volume; Radiotherapy; Radiothérapie; Set up margins; Volume cible interne; Volume cible prévisionnel