Modulation, functionality, and cytocompatibility of three-dimensional printing materials made from chitosan-based polysaccharide composites.
The mechanical properties, cytocompatibility, and fabrication of three-dimensional (3D) printing strips of composite materials containing polylactide (PLA) and chitosan (CS) were evaluated. Maleic anhydride-grafted polylactide (PLA-g-MA) and CS were used to enhance the desired characteristics of these composites. The PLA-g-MA/CS materials exhibited better mechanical properties than the PLA/CS composites; this effect was attributed to a greater compatibility between the grafted polyester and CS. The water resistance of the PLA-g-MA/CS composites was greater than that of the PLA/CS composites; cytocompatibility evaluation with human foreskin fibroblasts (FBs) indicated that both materials were nontoxic. Moreover, CS enhanced the antibacterial activity properties of PLA-g-MA and PLA/CS composites.
Department of Chemical and Biochemical Engineering, Kao Yuan University, Kaohsiung County 82101, Taiwan, ROC. Electronic address: t50008@cc.kyu.edu.tw.
Chin-San
CS
Wu
D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D048271:Chitosan / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008299:Maleic Anhydrides / Q000737:chemistry; D011091:Polyesters / Q000737:chemistry*; D066330:Printing, Three-Dimensional; D013211:Staphylococcus aureus / Q000187:drug effects; D013718:Tensile Strength; D014867:Water / Q000737:chemistry
D001672:Biocompatible Materials; D008299:Maleic Anhydrides; D011091:Polyesters; D014867:Water; C033616:poly(lactide); D048271:Chitosan
3D printing strips; Antibacterial activity; Chitosan; Cytocompatibility; Polymer-matrix composites