A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion.
BACKGROUND
This study was done to evaluate remineralizing potential of bioactive glasses (BAGs) and amorphous calcium phosphate-casein phosphopeptide (ACP-CPP) on early enamel lesion.


METHODS
Twenty freshly extracted mandibular premolars were sectioned sagittally. The buccal half was impregnated in acrylic resin blocks and treated with 37% phosphoric acid in liquid form, to demineralize enamel surface to simulate early enamel lesion. The samples were divided into two groups. The samples in Group I were treated with ACP-CPP (GC Tooth Mousse) and in Group II with BAG (Sensodyne Repair and Protect) and stored in saliva to prevent dehydration. The samples were tested for microhardness. The data obtained was analyzed using ANOVA post hoc multiple comparison and independent sample t- test and presented as a mean and standard deviation.


RESULTS
All the samples showed a decrease in the microhardness after demineralization. After application of remineralizing agents, Group II showed a highly significant increase in the microhardness (P < 0.05) after 10 days, while Group I showed a significant increase in microhardness after 15 days (P < 0.05).


CONCLUSIONS
Both the remineralizing agents tested in this study can be considered effective in repair and prevention of demineralization. BAG showed better results initially, but eventually both have similar remineralizing potential.
Department of Conservative Dentistry and Endodontics, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India.
Udaya Kumar
UK
Palaniswamy
Department of Conservative Dentistry and Endodontics Army College of Dental Sciences, Secunderabad, Telangana, India.
Neha
N
Prashar
Department of Conservative Dentistry and Endodontics Army College of Dental Sciences, Secunderabad, Telangana, India.
Mamta
M
Kaushik
Department of Conservative Dentistry and Endodontics, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India.
Surender Ram
SR
Lakkam
Department of Conservative Dentistry and Endodontics, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India.
Shikha
S
Arya
Department of Conservative Dentistry and Endodontics, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India.
Swetha
S
Pebbeti
Casein phosphopeptide-amorphous calcium phosphate nanocomplex; NovaMin; enamel; hardness; number; remineralization