An Update on Canine, Feline and Bovine Papillomaviruses.
Over recent years, a growing number of papillomaviruses have been identified, which cause a wide range of lesions in domestic and wild animals. Papillomavirus-induced lesions may have a great impact on animal health, and some diseases observed in farm animals are associated with significant economic losses. This concise review brings together recent advancements on animal papillomavirus research, providing the scientific community and veterinary practitioners with an update on this rapidly evolving field. Among others, bovine, canine and feline papillomaviruses (BPV, CPV and FcaPV) are most extensively discussed, in view of the recent discovery of new viral types and their worldwide importance for animal health. Feline papillomaviruses 2 is an emerging, highly prevalent pathogen in domestic cats, associated with a subset of malignant skin lesions. Aspects related to cross-species infection by BPV and its environmental co-factors are also addressed. Animal papillomaviruses are also fascinating models for studying molecular and cell biology and have recently inspired some major breakthroughs. Overall, it is clear that additional, international and systematic efforts are needed to clarify which lesions are caused by which viral types and to develop experimental models for studying animal papillomavirus.
LEPABE, Chemical Engineering Department, Faculty of Engineering, University of Porto (FEUP), Porto, Portugal.|Molecular Oncology and Viral Pathology Group, CI-IPOP, Portuguese Institute of Oncology, Porto, Portugal.
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Gil da Costa
Faculty of Veterinary Medicine, CIISA, University of Lisbon, Lisboa, Portugal.
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Peleteiro
Veterinary Sciences Department, CECAV, University of Trás-os-Montes e Alto Douro (UTAD), Vila Real, Portugal.
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Pires
Department of Genetics, Yale School of Medicine, New Haven, CT, USA.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.|Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA.|Yale Cancer Center, New Haven, CT, USA.
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DiMaio
D000827:Animal Welfare; D000818:Animals; D002371:Cat Diseases / Q000473:pathology / Q000821:virology*; D002415:Cats; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology / Q000821:virology*; D004283:Dog Diseases / Q000473:pathology / Q000821:virology*; D004285:Dogs; D027383:Papillomaviridae / Q000145:classification*; D030361:Papillomavirus Infections / Q000473:pathology / Q000662:veterinary* / Q000821:virology
bovine papillomaviruse; cancer; canine; feline; human papillomavirus; papillomavirus