Hashimoto's Encephalopathy Presenting with Chorea.
Hashimoto's encephalopathy (HE) is a steroid-responsive relapsing neuropsychiatric disorder associated with high titers of antithyroid antibody with or without thyroid dysfunction. We report a case of HE in a 78 year old female who developed sudden onset behavioral abnormalities associated with choreiform movement of extremities. All causes of vascular, infective, metabolic, autoimmune, paraneoplastic and toxic encephalopathy were excluded. Anti-thyroid peroxidase (anti-TPO) antibody was found to be raised with very high titre. A diagnosis of HE was made. Prompt treatment with high dose steroid led to dramatic improvement of symptoms including choreiform movement.
Postgraduate Trainee.
Abhijeet
A
Sharan
Additional Chief Heath Director.
Sarbani
S
Sengupta
Senior Divisional Medical Officer, B.R. Singh Hospital and Centre for Medical Research and Education, Kolkata, West Bengal.
Sarmishtha
S
Mukhopadhyay
Additional Chief Heath Director.
Bhaskar
B
Ghosh