Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma.
Soma (Carisoprodol) is N-isopropyl-2 methyl-2-propyl-1,3-propanediol dicarbamate; a commonly prescribed, centrally acting skeletal muscle relaxant. Neuroleptic malignant syndrome (NMS) is a potentially life-threatening adverse effect of antipsychotic agents. Although diagnostic criteria for NMS have been established, it should be recognized that atypical presentations occur and more flexible diagnostic criteria than currently mandated, may be warranted. We wish to report a postoperative case of bilateral knee replacement who presented with carisoprodol (Soma) withdrawal resembling NMS that was a diagnostic dilemma. Subsequently, it was successfully treated with oral baclofen in absence of sodium dantrolene.
Department of Critical Care Medicine, Dayanand Medical College, Ludhiana, Punjab, India.
Gunchan
G
Paul
Department of Critical Care Medicine, Dayanand Medical College, Ludhiana, Punjab, India.
Gautam L
GL
Parshotam
Department of Orthopedics, Dayanand Medical College, Ludhiana, Punjab, India.
Rajneesh
R
Garg
Carisoprodol; carisoprodol abuse; carisoprodol withdrawal; neuroleptic malignant syndrome; soma