Successful treatment of hemophagocytic lymphohistiocytosis and disseminated intravascular coagulation secondary to histoplasmosis in a patient with HIV/AIDS.
Haemophagocytic lymphohistiocytosis is an uncommon syndrome that results from an uncontrolled activation of macrophages and lymphocytes resulting in the compromise of multiple organs that is potentially fatal without timely treatment. It can be hereditary or a secondary result of infectious processes, neoplasms or autoimmune conditions. We present the case of a patient with HIV/AIDS who developed hemophagocytic lymphohistiocytosis as well as disseminated intravascular coagulation associated with histoplasmosis and who was successfully treated with amphotericin B, steroids and transitory dialytic support.
Departamento de Nefrología y Trasplante Renal, Hospital Pablo Tobón Uribe, Medellín, Colombia Departamento de Medicina Interna y Nefrología, Universidad de Antioquia, Medellín, Colombia. johnfredynieto@gmail.com.
John Fredy
JF
Nieto
Sandra Milena
SM
Gómez
Diana Carolina
DC
Moncada
Lina María
LM
Serna
Alicia Inés
AI
Hidrón
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000382:microbiology; D000666:Amphotericin B / Q000737:chemistry / Q000494:pharmacology*; D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000382:microbiology / Q000821:virology; D006660:Histoplasmosis / Q000150:complications*; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis / Q000382:microbiology
D000666:Amphotericin B
Lymphohistiocytosis; acquired immunodeficiency syndrome; disseminated intravascular coagulation; hemophagocytic; histoplasmosis