Rhodium-Catalyzed Regioselective Hydroxylation of Cage B-H Bonds of o-Carboranes with O2 or Air.
A rhodium-catalyzed hydroxylation of a cage B4-H bond in o-carboranes with either O2 or air as the oxygen source is described, and serves as a new methodology for the regioselective generation of a series of 4-OH-o-carboranes in a one-pot process. The use of either O2 or air as both the oxidant and the oxygen source makes this protocol very environmentally friendly and practical.
Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
Hairong
H
Lyu
Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
Yangjian
Y
Quan
Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. zxie@cuhk.edu.hk.
Zuowei
Z
Xie
B−H activation; carboranes; homogeneous catalysis; hydroxylation; rhodium