3D nanoporous gold scaffold supported on graphene paper: Freestanding and flexible electrode with high loading of ultrafine PtCo alloy nanoparticles for electrochemical glucose sensing.
Recent advances in on-body wearable medical apparatus and implantable devices drive the development of light-weight and bendable electrochemical sensors, which require the design of high-performance flexible electrode system. In this work, we reported a new type of freestanding and flexible electrode based on graphene paper (GP) supported 3D monolithic nanoporous gold (NPG) scaffold (NPG/GP), which was further modified by a layer of highly dense, well dispersed and ultrafine binary PtCo alloy nanoparticles via a facile and effective ultrasonic electrodeposition method. Our results demonstrated that benefited from the synergistic effect of the electrocatalytically active PtCo alloy nanoparticles, the large-active-area and highly conductive 3D NPG scaffold, and the mechanically strong and stable GP electrode substrate, the resultant PtCo alloy nanoparticles modified NPG/GP (PtCo/NPG/GP) exhibited high mechanical strength and good electrochemical sensing performances toward nonenzymatic detection of glucose, including a wide linear range from 35 μM- to 30 mM, a low detection limit of 5 μM (S/N = 3) and a high sensitivity of 7.84 μA cm(-2) mM(-1) as well as good selectivity, long-term stability and reproducibility. The practical application of the proposed PtCo/NPG/GP has also been demonstrated in in vitro detection of blood glucose in real clinic samples.
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, China.
Anshun
A
Zhao
Key Laboratory of Detection of Mycotoxins, Ministry of Agriculture, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Zhaowei
Z
Zhang
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, China.
Penghui
P
Zhang
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, China.
Shuang
S
Xiao
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, China.
Lu
L
Wang
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, China.
Yue
Y
Dong
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, China.
Hao
H
Yuan
Key Laboratory of Detection of Mycotoxins, Ministry of Agriculture, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Peiwu
P
Li
Hubei Key Laboratory of Plasma Chemistry and Advanced Materials, School of Materials Science and Engineering, Wuhan Institute of Technology, Wuhan 430073, China.
Yimin
Y
Sun
Hubei Key Laboratory of Plasma Chemistry and Advanced Materials, School of Materials Science and Engineering, Wuhan Institute of Technology, Wuhan 430073, China.
Xueliang
X
Jiang
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, China. Electronic address: xiaofei@hust.edu.cn.
Fei
F
Xiao
D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D006046:Gold / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D058608:Nanopores
D006046:Gold; D006108:Graphite; D005947:Glucose
Freestanding and flexible electrode; Graphene paper; Nanoporous gold; Nonenzymatic electrochemical glucose sensor; PtCo alloy nanoparticles