Antibiotic resistance.
Antimicrobial resistance in bacterial pathogens is a challenge that is associated with high morbidity and mortality. Multidrug resistance patterns in Gram-positive and -negative bacteria are difficult to treat and may even be untreatable with conventional antibiotics. There is currently a shortage of effective therapies, lack of successful prevention measures, and only a few new antibiotics, which require development of novel treatment options and alternative antimicrobial therapies. Biofilms are involved in multidrug resistance and can present challenges for infection control. Virulence, Staphylococcus aureus, Clostridium difficile infection, vancomycin-resistant enterococci, and control in the Emergency Department are also discussed.
Division of Allergy Immunology, Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, United States. Electronic address: mfrieri@numc.edu.
Marianne
M
Frieri
Division of Pediatric, Department of Emergency Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, United States. Electronic address: kkumar@numc.edu.
Krishan
K
Kumar
Adult Emergency Medicine, Department of Emergency Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, United States. Electronic address: aboutin@numc.edu.
Anthony
A
Boutin
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D006801:Humans
D000900:Anti-Bacterial Agents
Antibiotic resistance; Biofilms; Emergency Department; Infections; Public health