A novel simian retrovirus subtype discovered in cynomolgus monkeys (Macaca fascicularis).
A new simian retrovirus (SRV) subtype was discovered in China and the USA from Cambodian-origin cynomolgus monkeys. Histopathological examination from necropsied animals showed multifocal lymphoplasmacystic and histocytic inflammation. The complete genome sequences demonstrated that the US virus isolates were nearly identical (99.91-99.93 %) and differed only slightly (99.13-99.16 % identical) from the China isolate. Phylogenetic analysis showed that the new virus isolates formed a distinct branch of SRV-1 through -7, and therefore were named this subtype, SRV-8. This SRV-8 variant was also phylogenetically and serologically more closely related to SRV-4 than any other SRV subtype.
VRL-San Antonio, San Antonio, TX, USA.
Chih-Ling
CL
Zao
VRL-San Antonio, San Antonio, TX, USA.
Lisa
L
Tomanek
VRL-San Antonio, San Antonio, TX, USA.
Anthony
A
Cooke
VRL-San Antonio, San Antonio, TX, USA.
Ron
R
Berger
VRL-China, Suzhou, PR China.
Lingyan
L
Yang
Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, PR China.
Chen
C
Xie
VRL-China, Suzhou, PR China.
Si
S
Chen
VRL-China, Suzhou, PR China.
Changjun
C
Shi
Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, PR China.
Rong
R
Rong
D000818:Animals; D008252:Macaca fascicularis / Q000821:virology; D008992:Monkey Diseases / Q000821:virology*; D016366:Open Reading Frames; D010802:Phylogeny; D012192:Retroviridae Infections / Q000662:veterinary* / Q000821:virology; D015301:Retroviruses, Simian / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D014764:Viral Proteins / Q000235:genetics
D014764:Viral Proteins