Menstrual Bleeding as a Manifestation of Mini-Puberty of Infancy in Severe Prematurity.
We report 2 infants with severe prematurity who presented with uterine bleeding at age 6 months (approximately 2.5 months corrected for gestational age). Mini-puberty of infancy should be considered in the differential diagnosis of girls who present with uterine bleeding during the first 6 months of life.
Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA. Electronic address: vogiatzim@email.chop.edu.
Maria G
MG
Vogiatzi
Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA.
Michelle
M
Pitt
Division of Pediatric Endocrinology, Diabetes, and Metabolism, Columbia University College of Medicine, New York Presbyterian, Morgan Stanley Children's Hospital, New York, NY.
Sharon
S
Oberfield
Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA.
Craig A
CA
Alter
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007234:Infant, Premature; D008598:Menstruation; D011627:Puberty / Q000502:physiology*; D014592:Uterine Hemorrhage / Q000175:diagnosis* / Q000209:etiology
case report; menstruation; mini-puberty of infancy; prematurity