Decreasing prevalence and time trend of gastroschisis in 14 cities of Liaoning Province: 2006-2015.
To identify trends in the prevalence of gastroschisis on the basis of a large population-based observation study with cases identified by the Liaoning Birth Defects Registry including 14 cities over the course of a 10-year period. Data were obtained from the aforementioned registry which was maintained by the Liaoning Women and Children's Health Hospital, a comprehensive care institution as well as being responsible for the women's and children's health care guidance in this province. Gastroschisis prevalence, percent change, annual percent change (APC), and contribution rates of each city were calculated. We observed 747 cases of gastroschisis among 3,248,954 live births, for a prevalence of 2.30 per 10,000 births. The gastroschisis prevalence significantly decreased by 12.63% per year in Liaoning Province. Although the decreasing trends were observed in all these 14 cities, significant results were only observed in Shenyang (APC = -16.31%), Tieling (APC = -20.23%), and Chaoyang (APC = -13.50%). Notably, Tieling, Shenyang, and Yingkou were the three major cities which contributed almost 37.17% of the decreasing trend of gastroschisis in Liaoning Province. In conclusion, our findings demonstrate that the prevalence of gastroschisis has been decreasing during the recent decade among 14 cities in Liaoning Province.
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Na
N
Li
Liaoning Women and Children's Health Hospital, Shenyang, China.
Yan-Ling
YL
Chen
Department of science and education, Shenyang Women and Children Health Care Centre, Shenyang, China.
Jing
J
Li
Department of children's health prevention, Shenyang Women and Children Health Care Centre, Shenyang, China.
Li-Li
LL
Li
School of Environmental and Chemical Engineering, Shenyang Ligong University, Shenyang, China.
Cheng-Zhi
CZ
Jiang
Department of information statistics, Shenyang Women and Children Health Care Centre, Shenyang, China.
Chen
C
Zhou
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Cai-Xia
CX
Liu
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Da
D
Li
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Ting-Ting
TT
Gong
Department of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Qi-Jun
QJ
Wu
Department of science and education, Shenyang Women and Children Health Care Centre, Shenyang, China.
Yan-Hong
YH
Huang
D000328:Adult; D002681:China / Q000453:epidemiology; D002947:Cities; D005260:Female; D020139:Gastroschisis / Q000175:diagnosis* / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D050498:Live Birth; D008423:Maternal Age; D011247:Pregnancy; D011296:Prenatal Diagnosis