Imaging of Spinal Cord Injury: Acute Cervical Spinal Cord Injury, Cervical Spondylotic Myelopathy, and Cord Herniation.
We review the pathophysiology and imaging findings of acute traumatic spinal cord injury (SCI), cervical spondylotic myelopathy, and briefly review the much less common cord herniation as a unique cause of myelopathy. Acute traumatic SCI is devastating to the patient and the costs to society are staggering. There are currently no "cures" for SCI and the only accepted pharmacologic treatment regimen for traumatic SCI is currently being questioned. Evaluation and prognostication of SCI is a demanding area with significant deficiencies, including lack of biomarkers. Accurate classification of SCI is heavily dependent on a good clinical examination, the results of which can vary substantially based upon the patient׳s condition or comorbidities and the skills of the examiner. Moreover, the full extent of a patients׳ neurologic injury may not become apparent for days after injury; by then, therapeutic response may be limited. Although magnetic resonance imaging (MRI) is the best imaging modality for the evaluation of spinal cord parenchyma, conventional MR techniques do not appear to differentiate edema from axonal injury. Recently, it is proposed that in addition to characterizing the anatomic extent of injury, metrics derived from conventional MRI and diffusion tensor imaging, in conjunction with the neurological examination, can serve as a reliable objective biomarker for determination of the extent of neurologic injury and early identification of patients who would benefit from treatment. Cervical spondylosis is a common disorder affecting predominantly the elderly with a potential to narrow the spinal canal and thereby impinge or compress upon the neural elements leading to cervical spondylotic myelopathy and radiculopathy. It is the commonest nontraumatic cause of spinal cord disorder in adults. Imaging plays an important role in grading the severity of spondylosis and detecting cord abnormalities suggesting myelopathy.
Section of Neuroradiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA. Electronic address: Kiran.Talekar@jefferson.edu.
Kiran
K
Talekar
Department of Radiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
Michael
M
Poplawski
Section of Neuroradiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
Rahul
R
Hegde
Department of Radiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
Mougnyan
M
Cox
Section of Neuroradiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
Adam
A
Flanders
D002574:Cervical Vertebrae / Q000000981:diagnostic imaging* / Q000293:injuries*; D003287:Contrast Media; D006801:Humans; D015601:Injury Severity Score; D008279:Magnetic Resonance Imaging / Q000379:methods*; D059906:Neuroimaging / Q000379:methods*; D013119:Spinal Cord Injuries / Q000000981:diagnostic imaging* / Q000503:physiopathology
D003287:Contrast Media