De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence.
Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohistochemical stain led to the accurate diagnosis. Early intervention with systemic chemotherapy regimens based on cytarabine is the treatment of choice. The role of chromosomal aberrations and genetic abnormality related to prognosis remain uncertain.
Department of Pathology, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.
Moumita
M
Sengupta
Department of Pathology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.
Indranil
I
Das
Department of Pathology, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.
Uttara
U
Chatterjee
Department of Pathology, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.
Boby
B
Majumdar
Acute myeloid leukemia; chloroma; monoblasts; myeloblasts; myeloid sarcoma