The relationship between baseline EEG spectra power and memory performance in older African Americans endorsing cognitive concerns in a community setting.
The finding that some older individuals report declines in aspects of cognitive functioning is becoming a frequently used criteria to identify elderly at risk for mild cognitive impairment (MCI) and dementia. Once concerns are identified in a community setting, however, effective means are necessary to pinpoint those individuals who should go on to more complex and costly diagnostic evaluations (e.g., functional imaging). We tested 44 African American volunteers endorsing cognitive concerns (37 females, 7 males) age≥65years with CogState battery subtests and recorded resting-state EEG, with eyes closed. After current source density (CSD) transformations of EEG recordings we obtained spectral power for delta, theta, alpha, and beta frequency bands. We characterized CogState One Card Back Learning (OCL, memory) with diffusion model parameters drift rate, boundary and non-decision time (NDT). Forward regression models showed that lower OCL drift rate, slower accumulation of information needed for decision making was linked to increased absolute and relative delta at occipital region. Lower drift rate was also linked to decrease in OCL theta power at parietal region, with no findings for ONB. Results show that cortical resting, eyes closed EEG rhythms are related to memory in African American seniors endorsing cognitive concerns. This study further supports the use of EEG as an easily accessible, cost-effective, culture-fair, and noninvasive clinical measurement that could provide potentially reliable diagnostic (and perhaps prognostic) information to differentiate at-risk from stable African American seniors.
Institute of Gerontology, Wayne State University, Detroit, MI, USA; Biomedical Research Institute, Ljubljana, Slovenia. Electronic address: Voykok@gmail.com.
Voyko
V
Kavcic
Biomedical Research Institute, Ljubljana, Slovenia; University Psychiatric Clinic, Ljubljana, Slovenia.
Bojan
B
Zalar
Departments of Psychiatry, Neurology, and Psychology and School of Nursing, University of Michigan, Ann Arbor, MI, USA.
Bruno
B
Giordani
D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D002540:Cerebral Cortex / Q000502:physiology*; D060825:Cognitive Dysfunction / Q000175:diagnosis / Q000503:physiopathology*; D003700:Delta Rhythm / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology*; D021641:Recognition, Psychology / Q000502:physiology*; D013826:Theta Rhythm / Q000502:physiology*
African Americans; Delta; Diffusion model; Recognition memory; Resting-state EEG; Theta