Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders.
The commercialization of new point of care technologies holds great potential in facilitating and advancing precision medicine in heart, lung, blood, and sleep (HLBS) disorders. The delivery of individually tailored health care to a patient depends on how well that patient's health condition can be interrogated and monitored. Point of care technologies may enable access to rapid and cost-effective interrogation of a patient's health condition in near real time. Currently, physiological data are largely limited to single-time-point collection at the hospital or clinic, whereas critical information on some conditions must be collected in the home, when symptoms occur, or at regular intervals over time. A variety of HLBS disorders are highly dependent on transient variables, such as patient activity level, environment, time of day, and so on. Consequently, the National Heart Lung and Blood Institute sponsored a request for applications to support the development and commercialization of novel point-of-care technologies through small businesses (RFA-HL-14-011 and RFA-HL-14-017). Three of the supported research projects are described to highlight particular point-of-care needs for HLBS disorders and the breadth of emerging technologies. While significant obstacles remain to the commercialization of such technologies, these advancements will be required to achieve precision medicine.
Diagnostic Biochips, Inc. Glen Burnie MD 21051 USA.
Mary Emma Gorham
ME
Bigelow
Diagnostic Biochips, Inc. Glen Burnie MD 21051 USA.
Brian G
BG
Jamieson
Electrical Engineering and Bioengineering Departments University of California at Los Angeles Los Angeles CA 90095 USA.
Chi On
CO
Chui
Electrical Engineering and Bioengineering Departments University of California at Los Angeles Los Angeles CA 90095 USA.
Yufei
Y
Mao
Electrical Engineering and Bioengineering Departments University of California at Los Angeles Los Angeles CA 90095 USA.
Kyeong-Sik
KS
Shin
Bioengineering Science and Mechanics Department The Pennsylvania State University University Park PA 16802 USA.
Tony Jun
TJ
Huang
Bioengineering Science and Mechanics Department The Pennsylvania State University University Park PA 16802 USA.
Po-Hsun
PH
Huang
Bioengineering Science and Mechanics Department The Pennsylvania State University University Park PA 16802 USA.
Liqiang
L
Ren
National Heart, Lung, and Blood Institute Bethesda MD 20892 USA.
Bishow
B
Adhikari
National Heart, Lung, and Blood Institute Bethesda MD 20892 USA.
Jue
J
Chen
National Heart, Lung, and Blood Institute Bethesda MD 20892 USA.
Erin
E
Iturriaga
Biosensor; commercialization; point-of-care technologies; precision medicine