Comparison study of different coatings on degradation performance and cell response of Mg-Sr alloy.
To solve the problem of rapid degradation for magnesium-based implants, surface modification especially coating method is widely studied and showed the great potential for clinical application. However, as concerned to the further application and medical translation for biodegradable magnesium alloys, there are still lack of data and comparisons among different coatings on their degradation and biological properties. This work studied three commonly used coatings on Mg-Sr alloy, including micro-arc oxidation coating, electrodeposition coating and chemical conversion coating, and compared these coatings for requirements of favorable degradation and biological performances, how each of these coating systems has performed. Finally the mechanism for the discrepancy between these coatings is proposed. The results indicate that the micro-arc oxidation coating on Mg-Sr alloy exhibited the best corrosion resistance and cell response among these coatings, and is proved to be more suitable for the orthopedic application.
Department of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China; Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China.
Yongming
Y
Shangguan
Jinzhou Medical University, Jinzhou 121000, China.
Lina
L
Sun
Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China; Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address: pwan@imr.ac.cn.
Peng
P
Wan
Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China.
Lili
L
Tan
Jinzhou Medical University, Jinzhou 121000, China.
Chengyue
C
Wang
Department of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Xinmin
X
Fan
Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Ling
L
Qin
Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China. Electronic address: kyang@imr.ac.cn.
Ke
K
Yang
D000497:Alloys / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D000818:Animals; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D020099:Coated Materials, Biocompatible / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D003343:Corrosion; D058266:Dielectric Spectroscopy; D051379:Mice; D008855:Microscopy, Electron, Scanning; D010084:Oxidation-Reduction; D019736:Prostheses and Implants; D013052:Spectrometry, X-Ray Emission; D013499:Surface Properties; D014961:X-Ray Diffraction
D000497:Alloys; D020099:Coated Materials, Biocompatible; C573915:Mg-Sr alloy
Coating; Degradation; Electrodeposition; Magnesium; Micro-arc oxidation