Exploring yale-brown obsessive-compulsive scale symptom structure in Iranian OCD patients using item-based factor analysis.
Obsessive compulsive disorder (OCD) is a heterogeneous psychiatric disorder. This study aimed to reach a comprehensive perspective of OCD symptoms in Iranian patients. Item-based factor analysis of Y-BOCS checklist from 216 outpatients resulted in five factors including aggression/checking, contamination/cleaning, symmetry/ordering/repeating/counting/hoarding, sexual and somatic. Regression analyses showed that miscellaneous items can be predicted by these factors. Results showed that OCD subtypes in Iranian patients resemble to those of other nations except the aggressive, sexual and religious obsessions; demonstrating the influence of the culture on obsession manifestation. The correlation analyses of factors and clinical characteristics demonstrated that aggression/checking was associated with high obsession scores and more avoidance. Contamination/cleaning was correlated with higher compulsion score. Patients with higher scores on symmetry/ordering/counting/repeating/hoarding had familial OCD pattern with earlier age of onset, lower age at assessment, higher obsession and more avoidance. Sexual factor was associated with less compulsion scores and somatic factor was associated with higher obsessions and compulsions as well as less familial history and more avoidance. These findings provide a comprehensive view of OCD symptom structure in Iranian OCD patients and will be of value to studies using symptom factor to lead investigation of its causes, correlates and treatment strategies considering cross-cultural differences.
NeuroBiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sareh
S
Asadi
Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azin
A
Daraeian
Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Section of Physiology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Behrouz
B
Rahmani
Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Atiye
A
Kargari
Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abolhassan
A
Ahmadiani
Behavioral Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: J_shams@sbmu.ac.ir.
Jamal
J
Shams
D000328:Adult; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000145:classification / Q000503:physiopathology*; D011569:Psychiatric Status Rating Scales; D055815:Young Adult
Compulsion; Factors; Miscellaneous items; Obsession; Phenotypic heterogeneity; Symptom dimensions; Y-BOCS