What is the role of the new β-lactam/β-lactamase inhibitors ceftolozane/tazobactam and ceftazidime/avibactam?
a Section of Infectious Diseases, Department of Clinical Medicine and Surgery , University of Naples 'Federico II' , Naples , Italy.
Ivan
I
Gentile
a Section of Infectious Diseases, Department of Clinical Medicine and Surgery , University of Naples 'Federico II' , Naples , Italy.
Alberto Enrico
AE
Maraolo
a Section of Infectious Diseases, Department of Clinical Medicine and Surgery , University of Naples 'Federico II' , Naples , Italy.
Guglielmo
G
Borgia
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D053961:Azabicyclo Compounds / Q000627:therapeutic use*; D002442:Ceftazidime / Q000627:therapeutic use*; D002511:Cephalosporins / Q000627:therapeutic use*; D004338:Drug Combinations; D024901:Drug Resistance, Multiple, Bacterial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D006801:Humans; D059413:Intraabdominal Infections / Q000188:drug therapy*; D010397:Penicillanic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011552:Pseudomonas Infections / Q000188:drug therapy*; D000078142:Tazobactam; D014552:Urinary Tract Infections / Q000188:drug therapy*; D065093:beta-Lactamase Inhibitors / Q000627:therapeutic use; D047090:beta-Lactams / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D053961:Azabicyclo Compounds; D002511:Cephalosporins; D004338:Drug Combinations; C000595613:avibactam, ceftazidime drug combination; D065093:beta-Lactamase Inhibitors; D047090:beta-Lactams; C000594038:ceftolozane, tazobactam drug combination; D010397:Penicillanic Acid; D002442:Ceftazidime; D000078142:Tazobactam
Ceftolozane/tazobactam; Enterobacteriaceae; Pseudomonas aeruginosa; carbapenem-sparing regimens; ceftazidime/avibactam; complicated intra-abdominal infections; complicated urinary tract infections; multidrug-resistance