Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review.
BACKGROUND
Thalidomide has been successful use in patients with refractory Crohn disease (CD) in recent years.


METHODS
We collected the data of a postoperative CD patient who was prescribed thalidomide to induce remission and reviewed the relevant literatures.


RESULTS
A 51-year-old female was diagnosed as CD after an urgent terminal intestinal resection and presented endoscopic recurrence despite the prophylactic treatment with azathioprine (AZA). Fortunately, she achieved mucosal healing (MH) at a low dose of thalidomide for 15 months.


CONCLUSIONS
Thalidomide is effective to induce MH in the postoperative CD endoscopic recurrence.
Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Huiqin
H
Hu
Xinying
X
Wang
Side
S
Liu
D053704:Capsule Endoscopy; D003113:Colonoscopy; D003424:Crohn Disease / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007413:Intestinal Mucosa / Q000187:drug effects; D008875:Middle Aged; D011184:Postoperative Period; D012008:Recurrence; D013792:Thalidomide / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D013792:Thalidomide