Use of Tolvaptan in a Patient With Palliated Congenital Heart Disease.
Heart failure is a common problem in the ever growing population of patients with palliated congenital heart disease. It is frequently complicated by hyponatremia that has been associated with increased morbidity and mortality. Tolvaptan is a vasopressin receptor antagonist that has been effective in improving hyponatremia and congestive symptoms in adults with chronic heart failure. We describe the short-term use of tolvaptan to treat hyponatremic hypervolemia in an adolescent patient with chronic heart failure in the setting of palliated congenital heart disease prior to definitive surgical intervention. In this case, the patient had improvement in hyponatremia and a decrease in body weight, without any adverse effects.
1 Division of Pediatric Cardiology, Department of Pediatrics, New York University School of Medicine, New York University Langone Medical Center, New York, NY, USA.
Sujata
S
Chakravarti
1 Division of Pediatric Cardiology, Department of Pediatrics, New York University School of Medicine, New York University Langone Medical Center, New York, NY, USA.
Melissa
M
Busovsky-McNeal
D000293:Adolescent; D065092:Antidiuretic Hormone Receptor Antagonists / Q000627:therapeutic use*; D001552:Benzazepines / Q000627:therapeutic use*; D006330:Heart Defects, Congenital / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D008297:Male; D000077602:Tolvaptan
D065092:Antidiuretic Hormone Receptor Antagonists; D001552:Benzazepines; D000077602:Tolvaptan
congenital heart disease; heart failure; pharmacology; preoperative care