Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico.
OBJECTIVE
To determine the frequency of nine sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico.


METHODS
Samples from 662 patients attending obstetrics and gynecology clinics were analyzed. Treponema pallidum, HIV, and HCV were detected by serology. HPV was detected by Polimerase Chain Reaction (PCR), and its genotype was determined by Restriction Fragment Length Polymorphism (RFLP). Trichomonas vaginalis, HSV-1, HSV-2, Mycoplasma genitalium, Neisseria gonorrhoeae and T. pallidum were detected by multiplex PCR.


RESULTS
By serology, HIV frequency was 6.8%, T. pallidum was 2.26%, and HCV was 0.15%. By PCR, HPV frequency was 13.9%, (more frequent genotype was 16, 33.7%), followed by T. vaginalis (14.2%), HSV-1 (8.5%), M. genitalium (2,41%), N. gonorrhoeae (2.11%), HSV-2 (1.8%), and T. pallidum (1.05%). Patients infected with T. vaginalis were more likely to have multiple coinfections (p = 0.01).


CONCLUSIONS
The frequency of HPV, HVS-1, HSV-2, M. genitalium and T. vaginalis was lower than that reported. However, a high frequency of HIV, T. pallidum, and N. gonorrhoeae was detected.
Néstor
N
Casillas-Vega
Rayo
R
Morfín-Otero
Santos
S
García
Jorge
J
Llaca-Díaz
Eduardo
E
Rodríguez-Noriega
Adrián
A
Camacho-Ortiz
Ma de la Merced
Mde L
Ayala-Castellanos
Soraya
S
Mendoza-Olazarán
Samantha
S
Flores-Treviño
Santiago
S
Petersen-Morfín
Héctor J
HJ
Maldonado-Garza
Francisco J
FJ
Bosques-Padilla
Elvira
E
Garza-González
D000293:Adolescent; D000328:Adult; D000368:Aged; D000554:Ambulatory Care Facilities; D060085:Coinfection; D005260:Female; D006176:Gynecology; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009774:Obstetrics; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000382:microbiology / Q000821:virology; D015995:Prevalence; D012307:Risk Factors; D012749:Sexually Transmitted Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D012959:Socioeconomic Factors; D055815:Young Adult