Short-term benefits of an unrestricted-calorie traditional Mediterranean diet, modified with a reduced consumption of carbohydrates at evening, in overweight-obese patients.
The Mediterranean diet (MeD) is believed to promote health; nevertheless, changes in the nutritional patterns in the Mediterranean area (increased intake of refined carbohydrates/saturated fats; reduced fibers intake; main calorie load shifted to dinner) led to reduced MeD benefits in recent decades. We retrospectively investigated the effects of a MeD with a low intake of refined carbohydrates in the evening ("MeDLowC") on body weight (BW) and metabolic profile of overweight/obese subjects. According to their adherence to MeDLowC, subjects were classified into 44 (41%) individuals with "excellent" adherence and 63 (59%) with "poor" adherence. Nutritional counseling induced an improvement in BW, glucose metabolism and liver transaminases in both groups, with an increased magnitude of these effects in the "Excellent" adherence group. "Excellent" adherence to MeDLowC improved insulin sensitivity and lipid metabolism. In conclusion, MeD with a restriction of carbohydrates in the evening significantly ameliorates obesity and associated metabolic complications.
a Clinica Medica "Augusto Murri", University of Bari "Aldo Moro" , Bari , Italy.|b Dipartimento Interdisciplinare di Medicina , University of Bari "Aldo Moro" , Bari , Italy.
Roberto
R
Salvia
a Clinica Medica "Augusto Murri", University of Bari "Aldo Moro" , Bari , Italy.|c National Cancer Research Centre , IRCCS Istituto Oncologico Giovanni Paolo II , Bari , Italy.
Simona
S
D'Amore
c National Cancer Research Centre , IRCCS Istituto Oncologico Giovanni Paolo II , Bari , Italy.
Giusi
G
Graziano
a Clinica Medica "Augusto Murri", University of Bari "Aldo Moro" , Bari , Italy.
Caterina
C
Capobianco
b Dipartimento Interdisciplinare di Medicina , University of Bari "Aldo Moro" , Bari , Italy.
Moris
M
Sangineto
a Clinica Medica "Augusto Murri", University of Bari "Aldo Moro" , Bari , Italy.
Domenico
D
Paparella
a Clinica Medica "Augusto Murri", University of Bari "Aldo Moro" , Bari , Italy.
Paola
P
de Bonfils
a Clinica Medica "Augusto Murri", University of Bari "Aldo Moro" , Bari , Italy.
Giuseppe
G
Palasciano
a Clinica Medica "Augusto Murri", University of Bari "Aldo Moro" , Bari , Italy.|b Dipartimento Interdisciplinare di Medicina , University of Bari "Aldo Moro" , Bari , Italy.
Michele
M
Vacca
D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D015992:Body Mass Index; D001835:Body Weight; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D038441:Diet, Mediterranean; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009765:Obesity; D050177:Overweight; D010349:Patient Compliance; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004040:Dietary Carbohydrates; D007328:Insulin; D014280:Triglycerides; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Mediterranean diet; carbohydrates; dyslipidemia; insulin resistance; metabolic syndrome; weight loss