Metal-free radical addition/cyclization of alkynoates with xanthates towards 3-(β-carbonyl)coumarins.
The dilauroyl peroxide (DLP)-promoted carboannulation of alkynoates with xanthates was developed, affording a series of 4-aryl-3-(β-carbonyl) coumarins in moderate to good yields. The difunctionalization of alkynoates was achieved via a radical addition/cyclization process under metal-free conditions.
School of Chemistry & Environmental Engineering, Jiangsu University of Technology, Changzhou 213001, P. R. China. panchangduo@jsut.edu.cn.
Changduo
C
Pan
Rongzhen
R
Chen
Weile
W
Shao
Jin-Tao
JT
Yu
D000480:Alkynes / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D003374:Coumarins / Q000737:chemistry*; D003500:Cyclization; D005609:Free Radicals / Q000737:chemistry
D000480:Alkynes; D002254:Carbonates; D003374:Coumarins; D005609:Free Radicals