Treatment of allergic children - Where is the progress (for the practicing allergist)?
For any kind of therapeutic intervention in allergic diseases such as environmental control, pharmacological, or immunomodulating treatment including educational programs, children are addressed separately from adults. Health authorities like the Food and Drug Administration in the United States of America or the European Medicine Agency in Europe request a specific 'Pediatric investigational plan' with studies addressing dose-response relationship, safety, and efficacy for infants, children, and adolescents. During the last 2 years, promising advances have been reported for the treatment of a variety of allergic and immunologic disorders. This review summarizes the progress in the treatment of pediatric asthma and allergic diseases, based on publications of approximately the last 2.5 years (end of 2013 until May 2016) in and beyond this journal. Meanwhile, it highlights areas with promising novel therapeutic approaches, which are likely to change treatment for allergic children in the near future.
Department of Paediatric Pneumology Allergy and Neonatology, Hannover Medical School, Hannover, Germany. wert.franziska@mh-hannover.de.
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Wert
Department of Paediatric Pneumology & Immunology, Charité Medical School, Berlin, Germany.
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Posa
Division of Asthma, Allergy and Lung Biology, Department of Paediatric Allergy, King's College London & Guy's, St. Thomas'National Health Service Foundation Trust, London, UK.
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Tsilochristou
Department of Paediatric Pneumology Allergy and Neonatology, Hannover Medical School, Hannover, Germany.
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Schwerk
D000293:Adolescent; D000328:Adult; D000072223:Allergists; D000818:Animals; D001249:Asthma / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005060:Europe; D006801:Humans; D006967:Hypersensitivity / Q000628:therapy*; D007223:Infant; D010353:Patient Education as Topic; D017410:Practice Guidelines as Topic; D014481:United States; D014486:United States Food and Drug Administration
allergic rhinitis; allergy; asthma; atopic dermatitis; chronic urticaria; food allergy; hereditary angio-edema; pediatric; treatment; vernal keratoconjunctivitis