Big Data: transforming drug development and health policy decision making.
The explosion of data sources, accompanied by the evolution of technology and analytical techniques, has created considerable challenges and opportunities for drug development and healthcare resource utilization. We present a systematic overview these phenomena, and suggest measures to be taken for effective integration of the new developments in the traditional medical research paradigm and health policy decision making. Special attention is paid to pertinent issues in emerging areas, including rare disease drug development, personalized medicine, Comparative Effectiveness Research, and privacy and confidentiality concerns.
Pfizer Inc., 235 East 42nd Street, New York, NY 10017 USA.
Demissie
D
Alemayehu
Pfizer Inc., 235 East 42nd Street, New York, NY 10017 USA.
Marc L
0000-0003-4322-3637
ML
Berger
Drug development; Keywords Big Data; Personalized medicine; Predictive analytics; Real world data