Effects of acute exercise on salivary free insulin-like growth factor 1 and interleukin 10 in sportsmen.
BACKGROUND
Saliva analysis is rapidly developing as a tool for the assessment of biomarkers of sports training. It remains poorly understood whether a short bout of sport training can alter some salivary immune biomarkers.


OBJECTIVE
To investigate the effect of acute exercise using football training session on salivary flow rate, salivary free Insulin-like Growth Factor-1 (IGF-1) and Interleukin 10 (IL-10).


METHODS
Saliva samples were collected before and immediately after a football session. Salivary flow rates, salivary levels of free IGF-1 and IL-10 (using ELISA) were determined. Data was analyzed and compared using Related Samples Wilcoxon Signed Rank test (non-parametric test). Relationships between salivary flow rate and levels of free IGF-1 and IL-10 were determined using Spearman correlation test.


RESULTS
There were 22 male footballers with a mean age of 20.46 years. Salivary flow rate reduced significantly (p = 0.01) after the training session while salivary levels of free IGF-1 and IL-10 did not show any significant change. Also, there were no correlations between salivary flow rates and salivary levels of free IGF-1 and IL-10 before and after exercise.


CONCLUSIONS
These findings suggest that acute exercise caused significant reduction in salivary flow rate but no change in the levels of salivary free IGF-1 and IL-10.
Departments of Physiology and Oral Pathology, College of Medicine, University of Ibadan, Nigeria.
Taye J
TJ
Lasisi
Department of Physiotherapy, University of Ibadan /University College Hospital, Ibadan.
Ade F
AF
Adeniyi
D056352:Athletes / Q000706:statistics & numerical data; D015331:Cohort Studies; D004797:Enzyme-Linked Immunosorbent Assay; D015444:Exercise / Q000502:physiology*; D005538:Football / Q000502:physiology; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D016753:Interleukin-10 / Q000032:analysis*; D008297:Male; D009549:Nigeria; D012016:Reference Values; D012463:Saliva / Q000276:immunology* / Q000378:metabolism*; D012469:Salivary Glands / Q000276:immunology* / Q000378:metabolism; D018709:Statistics, Nonparametric; D055815:Young Adult
D016753:Interleukin-10; D007334:Insulin-Like Growth Factor I
Insulin-like Growth Factor; Saliva; exercise; interleukin 10; salivary flow rate