Fetal Infection by Zika Virus in the Third Trimester: Report of 2 Cases.
Zika virus (ZIKV) infection acquired during pregnancy is associated with congenital microcephaly. We describe 2 cases of ZIKV infection in women in their 36th week of pregnancy whose fetuses had preserved head circumference at birth and findings of subependymal cysts and lenticulostriate vasculopathy in postnatal imaging. These represent the first signs of congenital brain injury acquired due to ZIKV in the third trimester.
Department of Radiology, Faculdade de Medicina de São José do Rio Preto (FAMERP).|Hospital da Criança e Maternidade.
Antonio
A
Soares de Souza
Hospital da Criança e Maternidade.
Cristiane
C
Moraes Dias
Hospital da Criança e Maternidade.
Fernanda Del Campo Braojos
FD
Braga
Laboratory of Virology, Department of Infectious and Dermatological Disease.
Ana Carolina Bernardes
AC
Terzian
Laboratory of Virology, Department of Infectious and Dermatological Disease.
Cássia Fernanda
CF
Estofolete
Department of Obstetrics and Gynecology.
Antonio Hélio
AH
Oliani
Hospital da Criança e Maternidade.
Gustavo Henrique
GH
Oliveira
Immunogenetics Laboratory, Department of Molecular Biology, FAMERP, São José do Rio Preto, São Paulo, Brazil.
Cinara Cássia
CC
Brandão de Mattos
Immunogenetics Laboratory, Department of Molecular Biology, FAMERP, São José do Rio Preto, São Paulo, Brazil.
Luiz Carlos
LC
de Mattos
Laboratory of Virology, Department of Infectious and Dermatological Disease.
Maurício Lacerda
ML
Nogueira
Hospital da Criança e Maternidade.|Department of Obstetrics and Gynecology.
Denise Cristina Mós
DC
Vaz-Oliani
D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000821:virology; D020863:Central Nervous System Cysts / Q000151:congenital / Q000000981:diagnostic imaging; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000821:virology*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000000981:diagnostic imaging; D011263:Pregnancy Trimester, Third; D017585:Ultrasonography, Doppler, Transcranial; D000071243:Zika Virus Infection / Q000150:complications
Zika virus infection; central nervous system cysts; infection/congenital; lenticulostriate vasculopathy; ultrasonography