Challenges In Early Glaucoma Detection.
BACKGROUND
Glaucoma is the most common optic neuropathy which is characterized by progressive loss of retinal ganglion cells, the excavation of the optic nerve head, associated with defects in the visual field. It is not a disease, but the final result of united and yet completely unidentified cellular and subcellular processes and effects of many factors responsible for changes in retinal ganglion cells leading to their accelerated apoptosis.


METHODS
This is a prospective-retrospective, comparative, randomized clinical trial that included 150 patients, 97 were female and 53 male. The age of patients ranged from 18 to 80 years.


RESULTS
The highest degree of myopia in category of tilted optic discs had patients with large disc (4.05 + -0.65). Values of the degree of myopia have linearly declined in relation to the size of the oblique disc. The analysis of the results revealed that the subjects who had a higher degree of myopia associated with glaucoma had frequent parapapillar atrophy of alpha and beta zones. The highest percentage of subjects with parapapillar changes were in the group of patients who had other than glaucoma and myopia (62%), then in the group of patients with glaucoma only (56%).


CONCLUSIONS
Previous studies on the relationship between myopia and open-angle glaucoma are based on the results of observational studies. However, according to recent findings, based on the available studies, the systematic approach to estimate the association between myopia and glaucoma does not exist. Disc Damage Likelihood Scale (DDLS) is a new system for assessing glaucomatous damage of the optic disc which strongly correlates with the degree of visual field loss.
Eye Clinic of the University Clinical Centre of Sarajevo.
Edita
E
Dervisevic
Eye Clinic of the University Clinical Centre of Sarajevo.
Suzana
S
Pavljasevic
Eye Clinic of the University Clinical Centre of Sarajevo.
Almir
A
Dervisevic
Eye Clinic of the University Clinical Centre of Sarajevo.
Sanja Sefic
SS
Kasumovic
D000328:Adult; D000368:Aged; D042241:Early Diagnosis; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000175:diagnosis*; D064887:Observational Studies as Topic; D009898:Optic Disk / Q000000981:diagnostic imaging* / Q000473:pathology; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors; D041623:Tomography, Optical Coherence; D014794:Visual Fields; D055815:Young Adult
early detection; glaucoma; optic neuropathy