A case of asymptomatic pancytopenia with clinical features of hemolysis as a presentation of pernicious anemia.
Pernicious anemia is an autoimmune disease with a variety of clinical presentations. We describe a case of pernicious anemia presenting with pancytopenia with hemolytic features. Further workup revealed very low vitamin B12 levels and elevated methylmalonic acid. It is important for a general internist to identify pernicious anemia as one of the cause of pancytopenia and hemolytic anemia to avoid extensive workup. Pernicious anemia can present strictly with hematological abnormalities without neurological problems or vice versa as in our case.
Mercy Health St Elizabeth Health Center, Youngstown, OH, USA; kumarkollipara.0308@gmail.com.
Venkateswara K
VK
Kollipara
Mercy Health St Elizabeth Health Center, Youngstown, OH, USA.
Patrick L
PL
Brine
Mercy Health St Elizabeth Health Center, Youngstown, OH, USA.
David
D
Gemmel
Mercy Health St Elizabeth Health Center, Youngstown, OH, USA.
Sisham
S
Ingnam
anti-intrinsic factor antibody; hemolytic anemia; intramedullary hemolysis; pancytopenia; pernicious anemia