Osseous Metaplasia (Cataracta Ossea) of Lens Remnants in Chronic Uveitis-A Clinicopathologic Report.
OBJECTIVE
To describe clinically and pathologically the rare occurrence of calcification and osseous metaplasia in lens remnants in both eyes of a patient with pseudophakic chronic uveitis.


METHODS
We performed 25-gauge pars plana vitrectomy, removal of dislocated intraocular lens (IOL), and secondary IOL fixation in the left eye. A similar procedure was performed in the right eye with 27-gauge pars plana vitrectomy.


RESULTS
The postoperative visual acuities were 20/30 OD and 20/125 OS. Hematoxylin and eosin staining demonstrated an abundance of calcified tissue and rare osteoclasts in lacunae, compatible with osseous metaplasia (cataracta ossea).


CONCLUSIONS
To our knowledge this is the first clinicopathologic report demonstrating cellular metaplasia that resulted in osseous transformation of the cortical lens remnants into bone in both eyes of a psuedophakic patient with chronic granulomatous pan uveitis of unknown etiology. The surgical technique described in the supplemental videos demonstrates an effective way of managing this complication.
a Department of Ophthalmology and Visual Sciences , University of Louisville , Louisville , Kentucky , USA.
Amir
A
Hadayer
a Department of Ophthalmology and Visual Sciences , University of Louisville , Louisville , Kentucky , USA.
Ahmet
A
Özkök
a Department of Ophthalmology and Visual Sciences , University of Louisville , Louisville , Kentucky , USA.
Henry J
HJ
Kaplan
a Department of Ophthalmology and Visual Sciences , University of Louisville , Louisville , Kentucky , USA.
Shlomit
S
Schaal
D002114:Calcinosis / Q000473:pathology* / Q000601:surgery; D002386:Cataract / Q000473:pathology*; D002387:Cataract Extraction; D002908:Chronic Disease; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007906:Lens Subluxation / Q000175:diagnosis / Q000601:surgery; D007908:Lens, Crystalline / Q000473:pathology*; D008679:Metaplasia; D008875:Middle Aged; D015864:Panuveitis / Q000150:complications*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
Bone metaplasia; IOL; cataracta ossea; chronic uveitis; cortical remnants; histology; osseous metaplasia