Generalized Bullous Fixed Drug Eruption due to Bromhexine.
We describe a patient with a generalized bullous form of Fixed Drug Eruption (FDE) induced by bromhexine, a commonly used drug for respiratory symptoms. This is a rare association and generalized bullous FDE is also very rare. We emphasize the importance of patch tests in identifying the culprit drug.
Department of Dermatology and Venereology, Centro Hospitalar de São João EPE, Porto, Portugal. juliavide@gmail.com.
J
J
Vide
C
C
Moreira
A P
AP
Cunha
H
H
Baldaia
S
S
Magina
F
F
Azevedo
D001964:Bromhexine / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005100:Expectorants / Q000009:adverse effects*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology
D005100:Expectorants; D001964:Bromhexine