Uremic pruritus treated successfully with the Goeckerman Program.
Uremic pruritus (UP) is a common condition among patients with chronic kidney disease (CKD) on hemodialysis (HD). We report 19 a case of severe UP recalcitrant to conventional therapy including topical corticosteroids, anti-histamines, and phototherapy, 20 which was treated successfully with the Goeckerman regimen consisting of topical coal tar, topical corticosteroids, and broadband 21 UVB (BB-UVB). Little is known about the pathophysiology of UP, and there is currently no consensus or evidence-based 22 treatments for UP. Although further studies are necessary, Goeckerman therapy may be a promising treatment option when 23 available for severe UP intractable to conventional therapies.
Department of Dermatology, University of California San Francisco. mio.nakamura@ucsf.edu.
Mio
M
Nakamura
John
J
Koo
Tina
T
Bhutani
D000279:Administration, Cutaneous; D000368:Aged; D003033:Coal Tar / Q000627:therapeutic use*; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008297:Male; D010778:Photochemotherapy; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology; D006435:Renal Dialysis; D014221:Triamcinolone / Q000627:therapeutic use*; D014467:Ultraviolet Therapy / Q000379:methods*; D014511:Uremia / Q000150:complications
D005938:Glucocorticoids; D007641:Keratolytic Agents; D014221:Triamcinolone; D003033:Coal Tar