Diffusion-weighted magnetic resonance imaging in colorectal cancer.
Magnetic resonance imaging (MRI) plays now a major role in patients with colorectal cancer regarding tumor staging, surgical planning, therapeutic decision, assessment of tumor response to chemoradiotherapy and surveillance of rectal cancer, and detection and characterization of liver or peritoneal metastasis of colorectal cancers. Diffusion-weighted MRI (DW-MRI) is a functional imaging tool that is now part of the standard MRI protocol for the investigation of patients with colorectal cancer. DW-MRI reflects micro-displacements of water molecules in tissues and conveys high degrees of accuracy to discriminate between benign and malignant colorectal conditions. Thus, in addition to morphological imaging, DW-MRI has an important role to accurately detect colorectal neoplasms and peritoneal implants, to differentiate benign focal liver lesions from metastases and to detect tumor relapse within fibrotic changes. This review provides a comprehensive overview of basic principles, clinical applications and future trends of DW-MRI in colorectal cancers.
Department of Body and Interventional Imaging, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75475 Paris, France; Université Diderot-Paris 7, Sorbonne Paris Cité, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France; UMR INSERM 965, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France.
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Barral
Department of digestive surgery, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France.
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Eveno
Department of Radiology, Hôpital Robert-Debré, CHU de Reims, 51092 Reims cedex, France.
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Hoeffel
Department of Body and Interventional Imaging, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75475 Paris, France.
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Boudiaf
Department of Body and Interventional Imaging, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75475 Paris, France. Electronic address: paul.bazeries@gmail.com.
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Bazeries
Department of Body and Interventional Imaging, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75475 Paris, France; Université Diderot-Paris 7, Sorbonne Paris Cité, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France.
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Foucher
Université Diderot-Paris 7, Sorbonne Paris Cité, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France; UMR INSERM 965, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France; Department of digestive surgery, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France.
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Pocard
UMR INSERM 965, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France.
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Dohan
Université Diderot-Paris 7, Sorbonne Paris Cité, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France; UMR INSERM 965, Hôpital Lariboisière, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: philippe.soyer@lrb.aphp.fr.
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Soyer
D015179:Colorectal Neoplasms / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D015203:Reproducibility of Results
Colon cancer; Diagnostic imaging; Diffusion-weighted magnetic resonance imaging; Rectal cancer; Tumor characterization; Tumor response