A survey on awareness of genetic counseling for non-invasive prenatal testing: the first year experience in Japan.
The purpose of this study is to summarize the results from a survey on awareness of genetic counseling for pregnant women who wish to receive non-invasive prenatal testing (NIPT) in Japan. As a component of a clinical study by the Japan NIPT Consortium, genetic counseling was conducted for women who wished to receive NIPT, and a questionnaire concerning both NIPT and genetic counseling was given twice: once after pre-test counseling and again when test results were reported. The responses of 7292 women were analyzed. They expressed high satisfaction with the genetic counseling system of the NIPT Consortium (94%). The number of respondents who indicated that genetic counseling is necessary for NIPT increased over time. Furthermore, they highly valued genetic counseling provided by skilled clinicians, such as clinical geneticists or genetic counselors. The vast majority (90%) responded that there was sufficient opportunity to consider the test ahead of time. Meanwhile, women who received positive test results had a poor opinion and expressed a low-degree satisfaction. We confirmed that the pre-test genetic counseling that we conducted creates an opportunity for pregnant women to sufficiently consider prenatal testing, promotes its understanding and has possibilities to effectively facilitate informed decision making after adequate consideration. A more careful and thorough approach is considered to be necessary for women who received positive test results.
Natural Science Division, Faculty of Core Research, Ochanomizu University, Tokyo, Japan.|Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
Junko
J
Yotsumoto
Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
Akihiko
A
Sekizawa
Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Nobuhiro
N
Suzumori
Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Takahiro
T
Yamada
Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Osamu
O
Samura
Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Miyuki
M
Nishiyama
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Kiyonori
K
Miura
Department of Obstetrics and Gynecology, Hyogo College of Medicine, Nishinomiya, Japan.
Hideaki
H
Sawai
Department of Maternal and Fetal Medicine, Tohoku University Graduate School of Medicine, Miyagi-Children's Hospital, Sendai, Japan.
Jun
J
Murotsuki
Department of Obstetrics and Gynecology, Sanno Hospital, Tokyo, Japan.
Michihiro
M
Kitagawa
Department of Obstetrics and Gynecology, Saitama Medical University Hospital, Saitama, Japan.
Yoshimasa
Y
Kamei
Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Hideaki
H
Masuzaki
Department of Obstetrics and Gynecology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Fumiki
F
Hirahara
Department of Obstetrics and Gynecology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Toshiaki
T
Endo
Department of Clinical Genetics, Iwate Medical University School of Medicine, Morioka, Japan.
Akimune
A
Fukushima
Department of Obstetrics and Gynecology, Saitama Medical University Hospital, Saitama, Japan.
Akira
A
Namba
Department of Obstetrics and Gynecology, Chiba University Graduate School of Medicine, Chiba, Japan.
Hisao
H
Osada
Department of Obstetrics and Gynecology, Japanese Red Cross Medical Center, Tokyo, Japan.
Yasuyo
Y
Kasai
Division of Clinical Genetics, Nippon Medical School Hospital, Tokyo, Japan.
Atsushi
A
Watanabe
Department of Obstetrics and Gynecology, Toho University Omori Medical Center, Tokyo, Japan.
Yukiko
Y
Katagiri
Department of Obstetrics and Gynecology, Toho University Omori Medical Center, Tokyo, Japan.
Naoki
N
Takeshita
Perinatal Medical Center, Tokyo Women's Medical University Hospital, Tokyo, Japan.
Masaki
M
Ogawa
Maternal and Child Health Center, Aiiku Hospital, Tokyo, Japan.
Takashi
T
Okai
Department of Obstetrics and Gynecology, Tokai University School of Medicine, Isehara, Japan.
Shunichiro
S
Izumi
Department of Obstetrics and Gynecology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Haruka
H
Hamanoue
Natural Science Division, Faculty of Core Research, Ochanomizu University, Tokyo, Japan.
Mayuko
M
Inuzuka
Department of Obstetrics and Gynecology, Niigata University Medical and Dental Hospital, Niigata, Japan.
Kazufumi
K
Haino
Department of Clinical Genetics, Nagoya City West Medical Center, Nagoya, Japan.
Naoki
N
Hamajima
Department of Obstetrics and Gynecology, Fujita Health University, Toyoake, Japan.
Haruki
H
Nishizawa
Department of Obstetrics, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Yoko
Y
Okamoto
Department of Obstetrics, Osaka City General Hospital, Osaka, Japan.
Hiroaki
H
Nakamura
Department of Obstetrics and Gynecology, Osaka University Faculty of Medicine, Osaka, Japan.
Takeshi
T
Kanegawa
Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center, Suita, Japan.
Jun
J
Yoshimatsu
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan.
Shinya
S
Tairaku
Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Japan.
Katsuhiko
K
Naruse
Okayama University Graduate School of Medicine, Okayama, Japan.
Hisashi
H
Masuyama
Hiroshima University Graduate School of Medicine, Hiroshima, Japan.
Maki
M
Hyodo
The University of Tokushima Faculty of Medicine, Tokushima, Japan.
Takashi
T
Kaji
Department of Obstetrics and Gynecology, Shikoku Medical Center for Children and Adults, Zentuji, Japan.
Kazuhisa
K
Maeda
Department of Obstetrics and Gynecology, Ehime University School of Medicine, Toon, Japan.
Keiichi
K
Matsubara
Department of Obstetrics and Gynecology, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
Masanobu
M
Ogawa
Center for Maternal, Fetal and Neonatal Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Toshiyuki
T
Yoshizato
Department of Obstetrics and Gynecology, Kumamoto University, Kumamoto, Japan.
Takashi
T
Ohba
Genetic Counselling Office, Oita University Hospital, Oita, Japan.
Yukie
Y
Kawano
Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Haruhiko
H
Sago
D000328:Adult; D001364:Awareness; D032882:Comprehension; D005260:Female; D005817:Genetic Counseling; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007564:Japan; D008875:Middle Aged; D017060:Patient Satisfaction; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods; D011795:Surveys and Questionnaires; D055815:Young Adult