Resistance training improves inflammatory level, lipid and glycemic profiles in obese older women: A randomized controlled trial.
The main purpose of the present study was to investigate the effect of resistance training on inflammatory levels, lipid and glycemic profile in obese older women. Thirty-eight obese older women (68.2±4.2years, and 41.0±6.2% of body fat) were randomly assigned to one of two groups: A training group (TG, n=19) that performed 8weeks of RT; or a control group (CG, n=19) that did not perform any type of exercise. The RT program consisted of 8 whole-body exercises for 3 sets of 10-15 repetition maximum (RM) carried out 3 times a week. Anthropometric, body composition (DXA), muscular strength (1RM), and blood sample measurements were performed pre- and post-training. After the intervention period, the TG demonstrated significantly (P<0.05) lower values than CG for interleukin-6 (TG=3.3±1.2pg/mL vs. CG=3.8±1.4pg/mL), tumor necrosis factor alpha (TG=3.1±1.5pg/mL vs. CG=3.5±1.8pg/mL), C-reactive protein (TG=1.8±1.4mg/L vs. CG=3.2±1.8mg/L), low-density lipoprotein (TG=85.1±11.0mg/dL vs. CG=148.7±0.1mg/dL), glucose (TG=90.8±11.1mg/dL vs. CG=97.9±6.9mg/dL), trunk fat (TG=12.7±3.5kg vs. CG=14.1±4.3kg), and total body fat (TG=37.5±5.7% vs. CG=43.1±5.6%). Furthermore, TG presented significantly (P<0.05) higher values for high-density lipoprotein (TG=58.3±15.4mg/dL vs. CG=55.2±11.8mg/dL). These results suggest that 8weeks of RT promote improvements on inflammatory levels, and the lipid and glycemic profile in obese older women. These findings further support the important role of RT in healthy aging.
Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil. Electronic address: crisieli@uol.com.br.
Crisieli M
CM
Tomeleri
Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil; Center for Research in Health Sciences, University of Northern Parana, Londrina, Brazil.
Alex S
AS
Ribeiro
Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.
Mariana F
MF
Souza
Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.
Durcelina
D
Schiavoni
Exercise Science Department, CUNY Lehman College, Bronx, New York, USA.
Brad J
BJ
Schoenfeld
Clinical Analyses Laboratory, Londrina State University, Londrina, Brazil.
Danielle
D
Venturini
Clinical Analyses Laboratory, Londrina State University, Londrina, Brazil.
Décio S
DS
Barbosa
Clinical Analyses Laboratory, Londrina State University, Londrina, Brazil.
Kamila
K
Landucci
Exercise and Health Laboratory, CIPER, Faculty of Human Kinetics, Universidade de Lisboa, Lisbon, Portugal.
Luís B
LB
Sardinha
Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.
Edilson S
ES
Cyrino
D000368:Aged; D000375:Aging / Q000097:blood*; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis*; D001823:Body Composition; D001938:Brazil; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D016014:Linear Models; D008055:Lipids / Q000097:blood*; D008875:Middle Aged; D053580:Muscle Strength; D009765:Obesity / Q000097:blood* / Q000534:rehabilitation*; D055070:Resistance Training; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
D001786:Blood Glucose; C508600:IL6 protein, human; D015850:Interleukin-6; D008055:Lipids; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein
Aging; IL-6; Strength training; TNF-α