Dose planning management of patients undergoing salvage whole brain radiation therapy after radiosurgery.
Dose or treatment planning management is necessary for the re-irradiation of intracranial relapses after focal irradiation, radiosurgery, or stereotactic radiotherapy. The current clinical guidelines for metastatic brain tumors are the use of focal irradiation if the patient presents with 4 lesions or less. Salvage treatments with the use of whole brain radiation therapy (WBRT) can then be used to limit disease progression if there is an intracranial relapse. However, salvage WBRT poses a number of challenges in dose planning to limit disease progression and preserve neurocognitive function. This work presents the dose planning management that addresses a method of delineating previously treated volumes, dose level matching, and the dose delivery techniques for WBRT.
Northeast Radiation Oncology Centers (NROC), Dunmore, PA. Electronic address: cheng.saw@aol.com.
Cheng B
CB
Saw
Northeast Radiation Oncology Centers (NROC), Dunmore, PA.
Frank
F
Battin
Northeast Radiation Oncology Centers (NROC), Dunmore, PA.
Janice
J
McKeague
Northeast Radiation Oncology Centers (NROC), Dunmore, PA.
Meghan
M
Haggerty
Northeast Radiation Oncology Centers (NROC), Dunmore, PA.
Madhava
M
Baikadi
Northeast Radiation Oncology Centers (NROC), Dunmore, PA.
Christopher
C
Peters
D001932:Brain Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D016371:Cranial Irradiation / Q000379:methods*; D006801:Humans; D016634:Radiosurgery / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D016879:Salvage Therapy / Q000379:methods*; D047368:Tumor Burden
Salvage radiation therapy; Tomotherapy; Treatment planning; WBRT; Whole brain