Adult Primary Spinal Epidural Extraosseous Ewing's Sarcoma: A Case Report and Review of the Literature.
Background. Extraosseous Ewing's sarcoma in the spinal epidural space is a rare malignancy, especially in adults. Case Presentation. A 40-year-old male presented with back pain and urinary hesitancy. MRI revealed a thoracic extradural mass with no osseous involvement. He underwent surgery for gross total resection of the mass, which was diagnosed as Ewing's sarcoma. He was subsequently treated with chemoradiotherapy. He remains disease-free 1 year after surgery. Review of the literature indicated only 45 previously reported cases of spinal epidural extraosseous Ewing's sarcoma in adults. Conclusions. Extraosseous Ewing's sarcoma in the spinal epidural space is a rare clinical entity that should be included in the differential for spinal epidural masses. Its treatment is multidisciplinary but frequently requires surgical intervention due to compressive neurologic symptoms. Gross total resection appears to correlate with improved outcomes.
Department of Neurosurgery, NYU School of Medicine, New York, NY 10016, USA.
Mark
0000-0002-4652-5449
M
Bustoros
Department of Pathology, NYU School of Medicine, New York, NY 10016, USA.
Cheddhi
C
Thomas
Department of Neurosurgery, NYU School of Medicine, New York, NY 10016, USA.
Joshua
0000-0003-2401-1575
J
Frenster
Department of Neurosurgery, NYU School of Medicine, New York, NY 10016, USA.
Aram S
AS
Modrek
Department of Neurosurgery, NYU School of Medicine, New York, NY 10016, USA.
N Sumru
NS
Bayin
Department of Pathology, NYU School of Medicine, New York, NY 10016, USA; Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016, USA; Brain Tumor Center, NYU Langone Medical Center, New York, NY 10016, USA.
Matija
M
Snuderl
Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016, USA; Department of Medicine, NYU School of Medicine, New York, NY 10016, USA.
Gerald
0000-0002-0337-5399
G
Rosen
Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016, USA; Department of Radiation Oncology, NYU School of Medicine, New York, NY 10016, USA.
Peter B
PB
Schiff
Department of Neurosurgery, NYU School of Medicine, New York, NY 10016, USA; Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016, USA; Brain Tumor Center, NYU Langone Medical Center, New York, NY 10016, USA; Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY 10016, USA.
Dimitris G
0000-0003-1950-2978
DG
Placantonakis