A retrospective single centre review of the incidence and prognostic significance of persistent foetal right umbilical vein.
The objective of our study was to appraise the incidence and significance of persistent right umbilical vein (PRUV), the most common foetal venous aberration. Based on a south Indian antenatal cohort, we identified 23 cases of PRUV amongst 20,452 foetuses of consecutive pregnancies, from 2009 to 2014, yielding an incidence of 1 in 889 total births (0.11%). The median maternal age was 24 (IQR, 22-26) years, and median gestational age at diagnosis was 23 (IQR, 22-24) weeks. Intrahepatic drainage of PRUV was seen in 91.3% cases. In three cases (13%), ductus venosus was absent. In 52.2% of the cases, additional major abnormalities were observed - predominantly cardiovascular (39.1%). The common minor marker was single umbilical artery (13%). The karyotype was found to be normal in six cases (26%) which underwent invasive testing. When associated anomalies were inconsequential or absent, the postnatal outcome was good, which reflected in 60.9% of our cases.
a Centre for Infertility and Assisted Reproduction (CIMAR), Edappal Hospitals Private Limited , Edappal , Kerala , India.
Seneesh Vikraman
SV
Kumar
a Centre for Infertility and Assisted Reproduction (CIMAR), Edappal Hospitals Private Limited , Edappal , Kerala , India.
Vipin
V
Chandra
a Centre for Infertility and Assisted Reproduction (CIMAR), Edappal Hospitals Private Limited , Edappal , Kerala , India.
Bijoy
B
Balakrishnan
a Centre for Infertility and Assisted Reproduction (CIMAR), Edappal Hospitals Private Limited , Edappal , Kerala , India.
Meenu
M
Batra
a Centre for Infertility and Assisted Reproduction (CIMAR), Edappal Hospitals Private Limited , Edappal , Kerala , India.
Rekha
R
Kuriakose
a Centre for Infertility and Assisted Reproduction (CIMAR), Edappal Hospitals Private Limited , Edappal , Kerala , India.
Gopinathan
G
Kannoly
D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000453:epidemiology*; D005333:Fetus / Q000098:blood supply; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007621:Karyotyping; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D012189:Retrospective Studies; D014471:Umbilical Veins / Q000002:abnormalities* / Q000196:embryology; D055815:Young Adult
Absent ductus venosus; conotruncal cardiac anomaly; extrahepatic umbilical vein; foetal echocardiography; foetal venous aberration; persistent right umbilical vein