Adnexal germ cell carcinoma with bone metastases in pregnant women: case report and review.
Germ cell carcinoma during pregnancy is rare. However, its detection has increased due to the use of ultrasound fetal monitoring in the antenatal care program. In this article, we present the case of a Germ cell carcinoma during pregnancy is rare. However, its detection has increased due to the use of ultrasound fetal monitoring in the antenatal care program. In this article, we present the case of a pregnant 27-year-old diagnosed with an adnexal germ cell carcinoma at six weeks of gestation, whose initial approach was local resection (suboptimal cytoreduction). Four weeks after surgery, the patient presented with grade IV peripheral neuropathy in the lower limbs; magnetic resonance imaging scan indicated an infiltrative lesion at D5. The local medical board decided on chemotherapy starting on the 19th week of gestation. The rest of the pregnancy period was uneventful and the patient had a cesarean section at 34 weeks of gestation and a live newborn with no complications. Unfortunately, four days after caesarean section, the patient died of a septic shock with respiratory focus.
Facultad de Medicina, Universidad Peruana de Ciencias Aplicada, Lima, Perú. Address: Avenida Alameda esquina San Marcos, Cuadra 2, Chorrillos, Lima, Perú. Email: mtg_mm@hotmail.com.
María Del Rosario
Mdel R
Tenorio-Guadalupe
Facultad de Medicina, Universidad Peruana de Ciencias Aplicada, Lima, Perú
Valeria
V
Arsentales-Montalva
Facultad de Medicina, Universidad Peruana de Ciencias Aplicada, Lima, Perú
Yessabell Sonia
YS
Yonz-Buendía
Facultad de Medicina, Universidad Peruana de Ciencias Aplicada, Lima, Perú; Instituto de Evaluación de Tecnologías en Salud e Investigación, Seguro Social de Salud, Lima, Perú
Fabián
F
Fiestas-Saldarriaga
Instituto de Evaluación de Tecnologías en Salud e Investigación, Seguro Social de Salud, Lima, Perú
Patricia
P
Pimentel-Álvarez
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy; D002585:Cesarean Section; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011256:Pregnancy Outcome; D012772:Shock, Septic / Q000175:diagnosis
D000970:Antineoplastic Agents
chemotherapy; germ cell tumor; neoplastic pregnancy complication