Ultraviolet Photodissociation Induced by Light-Emitting Diodes in a Planar Ion Trap.
The first application of light-emitting diodes (LEDs) for ultraviolet photodissociation (UVPD) mass spectrometry is reported. LEDs provide a compact, low cost light source and have been incorporated directly into the trapping cell of an Orbitrap mass spectrometer. MS/MS efficiencies of over 50 % were obtained using an extended irradiation period, and UVPD was optimized by modulating the ion trapping parameters to maximize the overlap between the ion cloud and the irradiation volume.
Department of Chemistry, The University of Texas at Austin, 105 E. 24th St, Austin, TX, 78712, USA.
Dustin D
DD
Holden
Thermo Fisher Scientific (Bremen) GmbH, Hanna-Kunath-Strasse 11, 28199, Bremen, Germany.
Alexander
A
Makarov
Thermo Fisher Scientific Inc., 355 River Oaks Pkwy, San Jose, CA, 95134, USA.
Jae C
JC
Schwartz
Department of Chemistry, The University of Texas at Austin, 105 E. 24th St, Austin, TX, 78712, USA.
James D
JD
Sanders
Thermo Fisher Scientific Inc., 355 River Oaks Pkwy, San Jose, CA, 95134, USA.
Eugene
E
Zhuk
Department of Chemistry, The University of Texas at Austin, 105 E. 24th St, Austin, TX, 78712, USA. jbrodbelt@cm.utexas.edu.
Jennifer S
0000-0003-3207-0217
JS
Brodbelt
UV photodissociation; ion traps; light-emitting diodes; mass spectrometry