Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection.
The genetic markers associated with economic traits have been widely explored for animal breeding. Among these markers, single-nucleotide polymorphism (SNPs) are gradually becoming a prevalent and effective evaluation tool. Since SNPs only focus on the genetic sequences of interest, it thereby reduces the evaluation time and cost. Compared to traditional approaches, SNP genotyping techniques incorporate informative genetic background, improve the breeding prediction accuracy and acquiesce breeding quality on the farm. This article therefore reviews the typical procedures of animal breeding using SNPs and the current status of related techniques. The associated SNP information and genotyping techniques, including microarray and Lab-on-a-Chip based platforms, along with their potential are highlighted. Examples in pig and poultry with different SNP loci linked to high economic trait values are given. The recommendations for utilizing SNP genotyping in nimal breeding are summarized.
Department of Animal Science, National Taiwan University, Taipei 10617, Taiwan. d98626004@ntu.edu.tw.
Chao-Wei
CW
Huang
Department of Bio-Industrial Mechatronics Engineering, National Taiwan University, Taipei 10617, Taiwan. pqf292@gmail.com.
Yu-Tsung
YT
Lin
Department of Animal Science, National Taiwan University, Taipei 10617, Taiwan. sding@ntu.edu.tw.
Shih-Torng
ST
Ding
Department of Animal Science, Chinese Culture University, Taipei 11114, Taiwan. loll@faculty.pccu.edu.tw.
Ling-Ling
LL
Lo
Department of Animal Science, National Taiwan University, Taipei 10617, Taiwan. demonwang@ntu.edu.tw.
Pei-Hwa
PH
Wang
Department of Animal Science, National Taiwan University, Taipei 10617, Taiwan. eclin01@ntu.edu.tw.
En-Chung
EC
Lin
Department of Bio-Industrial Mechatronics Engineering, National Taiwan University, Taipei 10617, Taiwan. b97504092@ntu.edu.tw.
Fang-Wei
FW
Liu
Department of Bio-Industrial Mechatronics Engineering, National Taiwan University, Taipei 10617, Taiwan. yenwenlu@ntu.edu.tw.
Yen-Wen
YW
Lu
chicken; economic traits; marker-assisted selection (MAS); swine