Serum collagenase-2 and BMI levels in pregnant women with striae gravidarum.
OBJECTIVE
Striae gravidarum is a form of scarring on the skin observed during pregnancy and can cause serious cosmetic problems. Striae gravidarum may be influenced by hormonal changes, although the etiology is not clear. The aim of this study was to investigate whether body mass index (BMI) and serum collagenase-2 levels in pregnant women are related to the development of striae gravidarum.


METHODS
Thirty pregnant women with striae, 30 pregnant women without striae, and 32 health controls were enrolled in the study.


RESULTS
BMI and serum collagenase-2 levels were measured in the participants.


CONCLUSIONS
Pregnant women with striae gravidarum had increased serum collagenase-2 and BMI levels when compared to pregnant women without striae gravidarum and healthy controls (P < 0.05). The increase in serum collagenase-2 levels was related to the development of striae gravidarum alone, or secondary to BMI increase.
Department of Dermatology, Medical Faculty, KSU, Kahramanmaras, Turkey.
Perihan
P
Ozturk
Department of Obstetrics, Medical Faculty, KSU, Maternal-Foetal Medicine Unit, Kahramanmaras, Turkey.
Hakan
H
Kıran
Department of Biochemistry, Medical Faculty, KSU, Kahramanmaras, Turkey.
Ergul Belge
EB
Kurutas
Department of Dermatology, Medical Faculty, KSU, Kahramanmaras, Turkey.
Kamil
K
Mulayim
Department of Obstetrics, Medical Faculty, KSU, Maternal-Foetal Medicine Unit, Kahramanmaras, Turkey.
Fazıl
F
Avcı
D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D020784:Matrix Metalloproteinase 8 / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000378:metabolism*; D057896:Striae Distensae / Q000201:enzymology*; D055815:Young Adult
D020784:Matrix Metalloproteinase 8

BMI
; Skin physiology/structure; collagenase-2; pregnant; striae gravidarum