Analysis of banned veterinary drugs and herbicide residues in shellfish by liquid chromatography-tandem mass spectrometry (LC/MS/MS) and gas chromatography-tandem mass spectrometry (GC/MS/MS).
Seafood safety is a crucial public health concern for consumers. In this study, we applied a validated method to analyze the residue of banned veterinary drugs in shellfish, namely chloramphenicol, malachite green, leucomalachite green, and nitrofuran metabolites; additionally, the QuEChERS method was employed to detect 76 herbicides by LC/MS/MS and GC/MS/MS. In total, 42 shellfish samples, which included hard clams, freshwater clams, and oysters, were collected from aquafarms and production areas in Taiwan during 2012. Our results revealed 3.8ng/g of chloramphenicol in one hard clam, 19.9-32.1ng/g of ametryn in two hard clams, 16.1-60.1ng/g of pendimethalin in four hard clams, and 17.0ng/g of mefenacet in one oyster, indicating that 19.1% of the samples contained residues from banned veterinary drugs and pesticides. These data can be used to monitor the residue of veterinary drugs and pesticides in aquatic organisms and as a reference for food safety.
Division of Residual Control, Agricultural Chemicals and Toxic Substance Research Institute, Council of Agriculture, 11 Guangming Road, Wufeng, Taichung 41358, Taiwan, ROC; Department of Veterinary Medicine, National Chiayi University, 580 Xinmin Road, Chiayi 60054, Taiwan, ROC. Electronic address: grchang@mail.ncyu.edu.tw.
Geng-Ruei
GR
Chang
Division of Residual Control, Agricultural Chemicals and Toxic Substance Research Institute, Council of Agriculture, 11 Guangming Road, Wufeng, Taichung 41358, Taiwan, ROC.
Hui-Shan
HS
Chen
Division of Residual Control, Agricultural Chemicals and Toxic Substance Research Institute, Council of Agriculture, 11 Guangming Road, Wufeng, Taichung 41358, Taiwan, ROC.
Feng-Yi
FY
Lin
D002849:Chromatography, Gas; D002853:Chromatography, Liquid; D005506:Food Contamination; D008401:Gas Chromatography-Mass Spectrometry; D006540:Herbicides / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D017747:Seafood; D012758:Shellfish; D053719:Tandem Mass Spectrometry; D019155:Veterinary Drugs / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis
D006540:Herbicides; D010573:Pesticide Residues; D019155:Veterinary Drugs; D014874:Water Pollutants, Chemical
Herbicides; Mass spectrometry; Residues; Shellfish; Veterinary drugs