[Resistance to the antimalarial drugs].
Malaria is one of the most widespread infectious diseases around the world with 214 million cases and 438,000 deaths in 2015. In the early twentieth century it was described for the first time the resistance to quinine and, since then, drug resistance to antimalarial drugs has spread up to represent a global challenge in the fight and control of malaria. Understanding the mechanisms, geography and monitoring tools that we can act against resistance to antimalarial drugs is critical to prevent its expansion.
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Rogelio López-Vélez, Unidad de Referencia Nacional para Enfermedades Tropicales. Servicio de Enfermedades Infecciosas. Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain. rogelio.lopezvelez@salud.madrid.org.
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D000962:Antimalarials / Q000494:pharmacology / Q000627:therapeutic use*; D004351:Drug Resistance / Q000187:drug effects*; D006801:Humans; D008288:Malaria / Q000188:drug therapy* / Q000469:parasitology; D010961:Plasmodium / Q000187:drug effects*; D011803:Quinine / Q000494:pharmacology / Q000627:therapeutic use
D000962:Antimalarials; D011803:Quinine