[Safety of surgical therapy for neonate aortic coarctation combined with ventricular septal defect].
OBJECTIVE
To evaluate the safety of surgical repair for neonatal aortic coarctation combined with ventricular septal defect.


METHODS
Twenty-three aortic coarctation neonates received surgical treatment and their clinical data between April, 2013 and May, 2015 were analyzed retrospectively. All patients underwent coarctation repair + ventricular septal defect repair and mild hyperthermia cardiopulmonary bypass under the condition of general anesthesia. All patients were subjected to delayed sternal closure.


RESULTS
One patient died at early post-operation, and no one died during 2-27 months' follow-up. Operation time, cardiopulmonary bypass time, aortic cross-clamp time, ICU stay time, mechanical ventilation time, delayed sternal closure time, and post-operative hospital stay time were (192.7±43.4) min, (132.4±26.4) min, (65.3±18.4) min, (185.3±56.4) h, (42.4±24.5) h, (36.3±18.6) h, and (15.3±4.6) d, respectively. Post-operative complications presented in 12 patients, including post-operative hemorrhage in 6 patients, acute renal insufficiency in 4 patients, wound infection in 1 patient, and post-operative coarctation of the aorta in 1 patient.


CONCLUSIONS
One-stage complete repair for severe aortic coarctation combined with ventricular septal defect in neonates is safe, and the outcomes are satisfied. Fully free of the aortic arch and individual aorta reconstruction are the keies to successful operation.
Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410006, China 2027576@qq.com.
Peng
P
Huang
Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410006, China.
Jinwen
J
Luo
Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410006, China.
Jian
J
Liu
Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410006, China.
Xiaohui
X
Yang
Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410006, China.
Xiaoming
X
Peng
Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410006, China.
Pingbo
P
Liu
D001011:Aorta; D001017:Aortic Coarctation; D006345:Heart Septal Defects, Ventricular; D006801:Humans; D007231:Infant, Newborn; D011183:Postoperative Complications; D011184:Postoperative Period; D012189:Retrospective Studies; D012449:Safety