Scedosporium apiospermum: a rare cause of malignant otitis externa.
A 79-year-old man, with a history of well-controlled diabetes mellitus, presented with left-sided otalgia. With an initial diagnosis of simple otitis externa, he was discharged on topical drops. He represented 2 months later with worsening otalgia and discharge. A diagnosis of malignant otitis externa was made based on clinical and radiological findings. Intravenous Tazocin and Gentamicin were given based on previous bacterial culture from ear swabs. The patient failed to improve and developed left-sided facial nerve palsy. His condition stabilised following a change in antimicrobial therapy and his management continued in the community on intravenous Meropenem with twice weekly aural toilet. Repeated nuclear medicine imaging failed to demonstrate resolution. A bony sequestration was removed from the external auditory canal in the outpatient clinic, which following extended culture grew Scedosporium apiospermum; his management was subsequently changed to oral Voriconazole. This led to rapid clinical improvement and disease resolution over a 6 -week period.
Department of ENT, South Devon NHS Foundation Trust, Torquay, Devon, UK.
Oliver
O
McLaren
Department of ENT, South Devon NHS Foundation Trust, Torquay, Devon, UK.
Christian
C
Potter
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D004431:Ear, External / Q000382:microbiology*; D006801:Humans; D008297:Male; D009181:Mycoses / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D010032:Otitis Externa / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D021681:Scedosporium / Q000254:growth & development*; D065819:Voriconazole / Q000627:therapeutic use
D000935:Antifungal Agents; D065819:Voriconazole