Clinical, Dialytic, and Laboratory Factors Associated With Poor Health-Related Quality of Life in Mexican Patients on Hemodialysis.
BACKGROUND
End-stage renal disease and its treatment have a negative impact on the quality of life of patients.


OBJECTIVE
To determine the clinical, dialytic, and laboratory factors associated with poor health-related quality of life in Mexican patients on hemodialysis.


METHODS
A multicenter, cross-sectional study. The KDQOL-SF36 v1.3 questionnaire was applied to patients with end-stage renal disease on hemodialysis in different regions of Mexico. Patients were classified according to their overall score on the questionnaire: poor health-related quality of life (overall score below the median) or good health-related quality of life (overall score above the median). Clinical, dialytic, and laboratory variables associated with poor health-related quality of life were analyzed using linear correlation and multivariate logistic regression.


RESULTS
We included 194 adult patients with a median age of 55 (45-64) years. The diagnosis of poor health-related quality of life was present in 47.4% of patients. A poor correlation was found between the clinical, dialytic, and biochemical parameters and the health-related quality of life score (range of correlations r = -0.4 to 0.2). Serum albumin level showed the highest number of weak, statistically significant correlations. Factors associated with poor health-related quality of life in the multivariate analysis were: time spent on hemodialysis (OR = 1.02; 95% CI; 1.00-1.04; p = 0.02), use of a venous catheter (OR = 3.2; 95% CI: 1.36-7.75; p = 0.01), and serum albumin < 4 g/dl (OR = 3.55; 95% CI: 1.44-8.74; p < 0.01).


CONCLUSIONS
Poor health-related quality of life was common in Mexican patients undergoing hemodialysis. No strong correlation was found between the clinical, dialytic, or laboratory factors with health-related quality of life. Factors associated with poor health-related quality of life were: time on hemodialysis, use of a venous catheter, and serum albumin level < 4 g/dl.
Hospital Civil de Culiacán, Sinaloa, Mexico.|Research and Teaching Center in Health Sciences (CIDOCS), Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, Mexico.
Edgar
E
Dehesa-López
Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Ricardo
R
Correa-Rotter
Hospital ISSSTE Ciudad Valles, San Luis Potosí, Mexico.
David
D
Olvera-Castillo
Hospital Christus Muguerza-UPAEP, Puebla, Mexico.
Carlos
C
González-Parra
Hospital ISSSTE Xalapa, Veracruz, Mexico.
Rafael
R
Baizabal-Olarte
D000328:Adult; D000368:Aged; D062905:Central Venous Catheters; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000628:therapy*; D016015:Logistic Models; D008297:Male; D008800:Mexico; D008875:Middle Aged; D015999:Multivariate Analysis; D011788:Quality of Life; D006435:Renal Dialysis / Q000379:methods*; D012709:Serum Albumin / Q000378:metabolism*; D011795:Surveys and Questionnaires; D013997:Time Factors
D012709:Serum Albumin