Response to Comment on "Principles of connectivity among morphologically defined cell types in adult neocortex".
The critique of Barth et al centers on three points: (i) the completeness of our study is overstated; (ii) the connectivity matrix we describe is biased by technical limitations of our brain-slicing and multipatching methods; and (iii) our cell classification scheme is arbitrary and we have simply renamed previously identified interneuron types. We address these criticisms in our Response.
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA. astolias@bcm.edu xiaolonj@bcm.edu.
Xiaolong
X
Jiang
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Shan
S
Shen
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Fabian
F
Sinz
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Jacob
J
Reimer
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Cathryn R
CR
Cadwell
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA. Bernstein Centre for Computational Neuroscience, Tübingen, Germany. Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany. Werner Reichardt Center for Integrative Neuroscience and Institute of Theoretical Physics, University of Tübingen, Tübingen, Germany.
Philipp
P
Berens
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA. Bernstein Centre for Computational Neuroscience, Tübingen, Germany. Werner Reichardt Center for Integrative Neuroscience and Institute of Theoretical Physics, University of Tübingen, Tübingen, Germany.
Alexander S
AS
Ecker
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Saumil
S
Patel
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
George H
GH
Denfield
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Emmanouil
E
Froudarakis
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Shuang
S
Li
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Edgar
E
Walker
Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA. Bernstein Centre for Computational Neuroscience, Tübingen, Germany. astolias@bcm.edu xiaolonj@bcm.edu.
Andreas S
AS
Tolias
D000328:Adult; D006801:Humans; D007395:Interneurons; D019579:Neocortex