What is the best way to manage screening for infections and vaccination of inflammatory bowel disease patients?
The use of biological agents and immunomodulators for inflammatory bowel disease (IBD) is associated with an increased risk of opportunistic infections, in particular of viral or bacterial etiology. Despite the existence of international guidelines, many gastroenterologists have not adopted routine screening and vaccination in those patients with IBD, which are candidate for biologic therapy. Available strategies to screen, diagnose and prevent bacterial and viral infections in patients with IBD prior to start biological therapy are discussed in this review.
Gianluca Andrisani, Alessandro Armuzzi, Manuela Marzo, Carla Felice, Daniela Pugliese, Alfredo Papa, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Gianluca
G
Andrisani
Gianluca Andrisani, Alessandro Armuzzi, Manuela Marzo, Carla Felice, Daniela Pugliese, Alfredo Papa, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Alessandro
A
Armuzzi
Gianluca Andrisani, Alessandro Armuzzi, Manuela Marzo, Carla Felice, Daniela Pugliese, Alfredo Papa, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Manuela
M
Marzo
Gianluca Andrisani, Alessandro Armuzzi, Manuela Marzo, Carla Felice, Daniela Pugliese, Alfredo Papa, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Carla
C
Felice
Gianluca Andrisani, Alessandro Armuzzi, Manuela Marzo, Carla Felice, Daniela Pugliese, Alfredo Papa, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Daniela
D
Pugliese
Gianluca Andrisani, Alessandro Armuzzi, Manuela Marzo, Carla Felice, Daniela Pugliese, Alfredo Papa, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Alfredo
A
Papa
Gianluca Andrisani, Alessandro Armuzzi, Manuela Marzo, Carla Felice, Daniela Pugliese, Alfredo Papa, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Luisa
L
Guidi
Anti-tumor necrosis factor agents; Corticosteroids; Immunomodulators; Inflammatory bowel disease; Opportunistic infections