Non-invasive treatment to grade 1 essential hypertension by percutaneous laser and electric pulse to acupoint with music: A randomized controlled trial.
OBJECTIVE
To study a non-drug therapy for hypertension disease by combining percutaneous laser and electric pulse stimulation to acupoint with music, and to test the efficiency of the combining treatment to grade 1 essential hypertension.


METHODS
A total of 174 patients with grade 1 essential hypertension were randomly assigned to 3 groups with a random number table after Chinese medicine (CM) syndrome differentiation: the photoelectric and musical treatment group (Group 1, with a self-developed multi-mode audio frequency pulse photoelectric therapeutic apparatus), acupuncture group (Group 2), and oral placebo group (Group 3), 58 cases per group. The curative effect of each group was evaluated by the changes of blood pressure and CM syndrome integral before and after treatment.


RESULTS
Compared with Group 3, there were significant decrease of blood pressure and CM syndrome integral in Group 1 and Group 2 (P<0.01). Compared with Group 2, Group 1 showed the highest decrease in systolic pressure (P<0.017). The total effective rate of anti-hypertension in Group 1 (91.38%, 53/58) was significantly higher than that in Group 2 (74.13%, 43/58) and Group 3 (18.97%, 11/58, P<0.05 or P<0.01); and that in Group 2 was also significantly higher than that in Group 3 (P<0.01). There were significant difference in the total effective rate of CM syndrome integral in both Group 1 (93.10%, 54/58) and Group 2 (84.48%, 49/58) as compared with Group 3 (17.24%, 10/58, P<0.01), while there was no significant difference between Group 1 and Group 2 (P>0.05).


CONCLUSIONS
The multi-mode audio frequency pulse photoelectric therapeutic apparatus, combining music, laser and electric pulse stimulation, is clinically useful for grade 1 essential hypertension. This "three in one" therapy method is non-invasive, easy and simple to handle. It is expected to be popularized as a new alternative treatment.
Department of Physical Medicine and Rehabilitation, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, 519000, China.
Hong-Rui
HR
Zhan
Department of Infectious Diseases, The Fifth Affiliated Hospital of Sun Yatsen University, Zhuhai, Guangdong Province, 519000, China.
Zhong-Si
ZS
Hong
Department of Pharmacy, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, 519000, China.
Yi-Shen
YS
Chen
Department of Otorhinolaryngology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, 519000, China.
Hai-Yu
HY
Hong
Department of General Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, 519000, China.
Ze-Bin
ZB
Weng
Department of Traditional Chinese Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, 519000, China. arrlom@sina.com.
Zhang-Bin
ZB
Yang
Department of Traditional Chinese Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, 519000, China.
Jing-Li
JL
Shi
Department of Biomedical Engineering, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Zhong-Ben
ZB
Chen
D015669:Acupuncture Points; D001794:Blood Pressure; D004599:Electric Stimulation Therapy; D000075222:Essential Hypertension; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology / Q000628:therapy*; D007834:Lasers; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D009146:Music; D013577:Syndrome; D016896:Treatment Outcome
grade 1 essential hypertension; laser and electric pulse stimulation to acupoint; multi-mode audio frequency pulse photoelectric therapeutic apparatus; musical treatment