Multicenter registry on inflammatory myositis from the Rheumatology Society in Madrid, Spain: Descriptive Analysis.
OBJECTIVE
To analyze clinical characteristics, survival and causes of death of patients diagnosed with autoimmune inflammatory myositis in the REMICAM registry from the Society of Rheumatology in the Community of Madrid (SORCOM).


METHODS
Multicenter cohort of patients diagnosed with autoimmune inflammatory myopathy with follow-up between January 1980 and December 2014. A total of 313 variables concerning demographic, clinical and morbidity data were collected, and a comparison was performed between clinical subgroups.


RESULTS
A total of 479 patients were recruited from 12 centers, with 14% of patients lost to follow-up. Seventy-four percent of cases were women, age at diagnosis of 44±23 years and a mean follow-up period of 10±8 years. The most frequent clinical subgroups were primary myositis (PM 29%, DM 22%), followed by overlap myositis (20.5%), juvenile myositis (18%), myositis associated with cancer (8%), immune-mediated necrotizing myositis (1%) and inclusion body myositis (1%). During the follow-up period, a total of 114 deaths (28%) were registered, the main causes being cancer (24%), infections (23%) and cardiovascular events (21%).


CONCLUSIONS
A total of 479 patients were recruited in the REMICAM registry of inflammatory myopathies. Including sociodemographic, clinical and prognostic information, it represents the largest Spanish multicenter registry to date in rheumatology, and constitutes an important source for conducting further substudies.
Servicio de Reumatología, Hospital La Paz, Madrid, España. Electronic address: lauranuno2@hotmail.com.
Laura
L
Nuño
Servicio de Reumatología, Hospital Doce de Octubre, Madrid, España.
Beatriz
B
Joven
Servicio de Reumatología, Hospital Doce de Octubre, Madrid, España.
Patricia
P
Carreira
Servicio de Reumatología, Hospital Ramón y Cajal, Madrid, España.
Valentina
V
Maldonado
Servicio de Reumatología, Hospital Ramón y Cajal, Madrid, España.
Carmen
C
Larena
Servicio de Reumatología, Hospital La Princesa, Madrid, España.
Irene
I
Llorente
Servicio de Reumatología, Hospital La Princesa, Madrid, España.
Eva
E
Tomero
Servicio de Reumatología, Hospital Puerta de Hierro, Madrid, España.
María Carmen
MC
Barbadillo
Servicio de Reumatología, Hospital Madrid Norte Sanchinarro, Madrid, España.
Paloma
P
García-de la Peña
Servicio de Reumatología, Hospital Infantil Niño Jesús, Madrid, España.
Lucía
L
Ruiz
Servicio de Reumatología, Hospital Infantil Niño Jesús, Madrid, España.
Juan Carlos
JC
López-Robledillo
Servicio de Reumatología, Hospital Príncipe de Asturias, Madrid, España.
Henry
H
Moruno
Servicio de Reumatología, Hospital Príncipe de Asturias, Madrid, España.
Ana
A
Pérez
Servicio de Reumatología, Hospital Infanta Sofía, Madrid, España.
Tatiana
T
Cobo-Ibáñez
Servicio de Reumatología, Hospital Fundación Alcorcón, Madrid, España.
Raquel
R
Almodóvar
Servicio de Reumatología, Hospital Infanta Leonor, Madrid, España.
Leticia
L
Lojo
Servicio de Reumatología, Hospital Gregorio Marañón, Madrid, España.
Indalecio
I
Monteagudo
Instituto de Salud Musculoesquelética, Madrid, España.
María Jesús
MJ
García-De Yébenes
Servicio de Reumatología, Hospital Gregorio Marañón, Madrid, España.
Francisco Javier
FJ
López-Longo
D000328:Adult; D002318:Cardiovascular Diseases / Q000401:mortality; D002423:Cause of Death; D015897:Comorbidity; D003882:Dermatomyositis / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D007239:Infections / Q000401:mortality; D008875:Middle Aged; D009220:Myositis / Q000145:classification / Q000453:epidemiology* / Q000209:etiology; D018979:Myositis, Inclusion Body / Q000453:epidemiology; D009369:Neoplasms / Q000401:mortality; D010257:Paraneoplastic Syndromes / Q000453:epidemiology; D012042:Registries; D012140:Respiratory Tract Diseases / Q000453:epidemiology; D012189:Retrospective Studies; D013030:Spain; D055815:Young Adult
Descriptive study; Estudio descriptivo; Idiopathic inflammatory myopathies; Miopatía inflamatoria idiopática; Registro; Registry