SPNsim: A database of simulated solitary pulmonary nodule PET/CT images facilitating computer aided diagnosis.
The aim of the present work was to design and develop a database of simulated solitary pulmonary nodules (SPN) in pairs of computed tomography (CT) and positron emission tomography (PET) images, using Monte Carlo (MC) simulation methods. We have developed an SPN image modeling pipeline to feed the database entitled SPNsim. The database is web-accessible and it is contains two subsets of simulated PET/CT SPN images. The first subset is currently composed of 1000 cases containing pairs of the transaxial CT and the corresponding PET slice with various types of simulated SPNs, presented as individual records. The second subset contains pairs of the transaxial CT and the corresponding PET slice of simulated SPNs, presenting cases of graded difficulty in diagnosis. The users of the database will have the ability to set queries in order to retrieve cases with certain characteristics, as well as characterized image sets. All images are freely available and may be downloaded from the website. SPNsim provides a useful reference data set for training and evaluation of computer aided detection (CAD) and diagnosis (CADx) systems focusing on SPN.
Department of Informatics and Telecommunications, University of Athens, Athens, Greece.
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Tzanoukos
Systems Biology Center, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.
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Athanasiadis
Nuclear Medicine Department and Small Animal PET/CT Unit, Clinical, Experimental Surgery & Translational Research Center, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.
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Gaitanis
Nuclear Medicine Department, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.
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Georgakopoulos
First Radiology Department, Aretaieion Hospital, University of Athens, Athens, Greece.
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Chatziioannou
Nuclear Medicine Department, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.
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Chatziioannou
Systems Biology Center, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece. Electronic address: gspyrou@bioacademy.gr.
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Spyrou
D016208:Databases, Factual; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007091:Image Processing, Computer-Assisted; D008175:Lung Neoplasms; D009010:Monte Carlo Method; D000072078:Positron Emission Tomography Computed Tomography; D049268:Positron-Emission Tomography; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
Image database; Monte Carlo image modeling; PET/CT imaging