Copper-Catalyzed Addition of H-P(O) Bonds to Arynes.
An efficient P-arylation of secondary phosphine oxides has been achieved through the ligand-free copper-catalyzed addition of H-P(O) bonds to in situ generated arynes at room temperature. This transformation provides a straightforward route to the formation of the aryl-P bond with wide functional group compatibility, which produces arylphosphine oxides in up to 99% yield.
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Qian
Q
Chen
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Xinxing
X
Yan
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Chunxiao
C
Wen
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Jiekun
J
Zeng
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Yulin
Y
Huang
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Xingguo
X
Liu
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Kun
K
Zhang