A Gold(I)-Catalyzed Domino Coupling of Alcohols with Allenes Enables the Synthesis of Highly Substituted Indenes.
The reaction of aryl-substituted allenes with alcohols under gold catalysis led to highly substituted indenes in good yields, with low catalyst loading and under mild conditions. During this domino transformation, two C-C bonds are formed with water as the only byproduct.
Faculty of Chemistry, Institute of Organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
Alexander
A
Preinfalk
Faculty of Chemistry, Institute of Organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
Antonio
A
Misale
Faculty of Chemistry, Institute of Organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria. nuno.maulide@univie.ac.at.
Nuno
N
Maulide
alcohols; allenes; domino coupling; gold catalysis; indenes