Leser-Trélat Sign in Tumor-Stage Mycosis Fungoides.
A 71-year-old man presented with numerous pruritic seborrheic keratoses, with an eruptive onset over the course of 3 months. At presentation, he was also found to have hypopigmented tumors diffusely scattered throughout his body that were found to be mycosis fungoides on histologic examination. A theory regarding the pathophysiology of the development of eruptive seborrheic keratoses in the presence of mycosis fungoides is briefly discussed and 10 previous case reports of the Leser-Trélat sign in the setting of mycosis fungoides are reviewed.
Department of Dermatology and Itch Center, Temple University School of Medicine.
Brandon
B
Rowe
Alina
A
Shevchenko
Gil
G
Yosipovitch
D000368:Aged; D006801:Humans; D017492:Keratosis, Seborrheic / Q000209:etiology / Q000473:pathology*; D008297:Male; D009182:Mycosis Fungoides / Q000150:complications / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*