Successful treatment of eosinophilic cellulitis with dapsone.
A 55-year-old woman presented with a 3-year history of recurrent episodes of pruritic cellulitis-like erythematous plaques, mostly located on the limbs. Simultaneously, fever, malaise and peripheral eosinophilia were noted. The clinical diagnosis of eosinophilic cellulitis (also known as Well's syndrome) was supported by the histopathological finding of typical "flame figures". Treatment with dapsone was initiated at a dose of 50 mg per day. After one year of follow-up the patient was relapse-free. Eosinophilic cellulitis is an uncommon, recurrent inflammatory skin disease. The management is often a challenge, due to the frequent need for long-term therapy. Dapsone is an effective and safe treatment option.
Department of Dermatology and Venereology, Hospital de Curry Cabral - Centro Hospitalar de Lisboa Central, Lisboa, Portugal. virginiacoelhodesousa@gmail.com.
Virgínia
V
Coelho de Sousa
André
A
Laureano Oliveira
Jorge
J
Cardoso
D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001132:Arm; D002481:Cellulitis / Q000188:drug therapy* / Q000473:pathology; D003622:Dapsone / Q000627:therapeutic use*; D004802:Eosinophilia / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D007868:Leg Dermatoses / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged
D000890:Anti-Infective Agents; D003622:Dapsone