[Margin determination from clinical to planning target volume for lung cancer treated with conformal or intensity-modulated irradiation].
Technological progress in radiotherapy enables more precision for treatment planning and delivery. The margin determination between the clinical target volume and the planning target volumes stem from the estimation of geometric uncertainties of the tumour localization into the radiation beam. The inner motion complexity of lung tumours has led to the use of 4D computed tomography and nurtures specific dosimetric concerns. Few strategies consisting in integrating tumour motion allow margin reduction regarding inner movements. The patient immobilization and onboard imagery improvement decrease the setup uncertainties. Each step between the initial planning imagery and treatment delivery has to be analysed as systematic or random errors to calculate the optimal planning margin.
Département de radiothérapie, centre Henri-Becquerel, rue d'Amiens, 76038 Rouen cedex 1, France.
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Berthelot
Département de médecine nucléaire, centre Henri-Becquerel, 1, rue d'Amiens, 76000 Rouen, France; Département de radiothérapie, centre Henri-Becquerel, 1, rue d'Amiens, 76000 Rouen, France; Laboratoire QuantIF, EA4108-Litis, FR CNRS 3638, 1, rue d'Amiens, 76000 Rouen, France.
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Thureau
Service d'oncologie radiothérapie, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France; Université Paris Descartes, Paris Sorbonne Cité, 12, rue de l'École-de-Médecine, 75006 Paris, France. Electronic address: philippe.giraud@aphp.fr.
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Giraud
D056973:Four-Dimensional Computed Tomography; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D056888:Patient Positioning; D015641:Radiography, Interventional; D011879:Radiotherapy Dosage; D061106:Radiotherapy Setup Errors / Q000517:prevention & control; D020266:Radiotherapy, Conformal; D061089:Radiotherapy, Image-Guided; D050397:Radiotherapy, Intensity-Modulated; D012119:Respiration
Cancers bronchiques; Conformal radiotherapy; Erreurs de positionnement; Image-guided radiotherapy; Inner motion; Intensity-modulated radiotherapy; Lung neoplasms; Marges; Margin; Mouvements internes; PTV; Radiothérapie avec modulation d’intensité; Radiothérapie conformationnelle; Radiothérapie guidée par l’image; Setup errors