Retrospective observational analysis of the use of an architecturally unique dermal regeneration template (Derma Pure®) for the treatment of hard-to-heal wounds.
The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application of DermaPure which was followed until complete closure. A statistical analysis was performed with the end point being complete healing. All wounds on average, had a duration of 56 weeks and healed in an average time of 10·58 weeks. Individual wound categories included diabetic foot ulcers, which healed in 8·21 weeks; venous leg ulcers, which healed in 11·29 weeks; and surgical/traumatic wounds, which healed in 11·8 weeks.
Department of Surgery, Buckeye Foot Care, Brook Park, OH, USA.
Howard
H
Kimmel
Case Comprehensive Cancer Center, Cleveland, OH, USA.
Haley
H
Gittleman
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D064591:Allografts / Q000637:transplantation*; D017719:Diabetic Foot / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012038:Regeneration / Q000502:physiology*; D012189:Retrospective Studies; D016038:Skin Transplantation / Q000379:methods*; D000072836:Surgical Wound / Q000601:surgery*; D014481:United States; D014647:Varicose Ulcer / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology*
CD31; DermaPure; Observational analysis; PROK2