Multidimensional Self-Assembled Structures of Alkylated Cellulose Oligomers Synthesized via in Vitro Enzymatic Reactions.
The self-assembly of biomolecules into highly ordered nano-to-macroscale structures is essential in the construction of biological tissues and organs. A variety of biomolecular assemblies composed of nucleic acids, peptides, and lipids have been used as molecular building units for self-assembled materials. However, crystalline polysaccharides have rarely been utilized in self-assembled materials. In this study, we describe multidimensional self-assembled structures of alkylated cellulose oligomers synthesized via in vitro enzymatic reactions. We found that the alkyl chain length drastically affected the assembled morphologies and allomorphs of cellulose moieties. The modulation of the intermolecular interactions of cellulose oligomers by alkyl substituents was highly effective at controlling their assembly into multidimensional structures. This study proposes a new potential of crystalline oligosaccharides for structural components of molecular assemblies with controlled morphologies and crystal structures.
Department of Organic and Polymeric Materials, Graduate School of Science and Engineering, Tokyo Institute of Technology , 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
Yusuke
Y
Yataka
Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology , 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
Toshiki
T
Sawada
Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology , 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
Takeshi
T
Serizawa
D002482:Cellulose / Q000138:chemical synthesis / Q000737:chemistry*; D048013:Acetivibrio thermocellus; D005964:Glucosyltransferases / Q000737:chemistry; D006017:Glycolipids / Q000138:chemical synthesis / Q000737:chemistry*; D020100:Hydrogels / Q000737:chemistry; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry*; D008823:Micelles; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis / Q000737:chemistry*
D006017:Glycolipids; D020100:Hydrogels; D046911:Macromolecular Substances; D008823:Micelles; D009844:Oligosaccharides; D002482:Cellulose; D005964:Glucosyltransferases; C105024:cellodextrin phosphorylase