Plesiomonas shigelloides Septic Shock Leading to Death of Postsplenectomy Patient with Pyruvate Kinase Deficiency and Hemochromatosis.
Although Plesiomonas shigelloides, a water-borne bacterium of the Enterobacteriaceae family, usually causes self-limiting gastroenteritis with diarrhea, several cases of sepsis have been reported. We report the case of a 43-year-old male patient with hemochromatosis, pyruvate kinase deficiency, and asplenia via splenectomy who developed septic shock caused by P. shigelloides complicated by respiratory failure, renal failure, liver failure, and disseminated intravascular coagulation. Early aggressive antimicrobial therapy and resuscitation measures were unsuccessful and the patient passed away. We kindly suggest clinicians to implement early diagnosis of septic shock, empirical coverage with antibiotics, and prompt volume resuscitation based on the high mortality rate of P. shigelloides bacteremia.
Department of Medicine, Buffalo Mercy Hospital, University at Buffalo, Buffalo, NY 14220, USA.
Mohammed
0000-0002-7937-5387
M
Samannodi
Department of Medicine, Buffalo Mercy Hospital, University at Buffalo, Buffalo, NY 14220, USA.
Andrew
0000-0003-4484-7812
A
Zhao
Department of Medicine, Buffalo Mercy Hospital, University at Buffalo, Buffalo, NY 14220, USA.
Yaser
0000-0003-1630-0545
Y
Nemshah
Department of Medicine, Buffalo Mercy Hospital, University at Buffalo, Buffalo, NY 14220, USA.
Kevin
0000-0003-0050-0550
K
Shiley