The Immunogenicity of Peptoid-Protein Conjugates.
We demonstrate that a peptoid composed of five monomers and attachedviaa maleimide linker to a carrier protein elicits anti-peptoid, anti-linker and anti-carrier antibodies in rabbits. Specific anti-peptoid antibodies were affinity purified and used to reproducibly retrieve three specific peptoid-coupled beads from 20,000 irrelevant peptoid-beads using magnetic screening.
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Bioengineering, The University of Texas at Dallas, Texas, USA.
Allison
A
Case
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Angela
A
Desmond
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Eli Lilly, Indianapolis, Indiana, USA.
Daniel
D
Lopes
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Kelly
K
Dye
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kelly
K
Mapes
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Stephen
S
Ruback
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Iliodora
I
Pop
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; College of Pharmacy, Pusan National University, Busan, Republic of Korea.
Jiyeun Kate
JK
Kim
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Pavitra
P
Chakravarty
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Joan E
JE
Smallshaw
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Laurentiu M
LM
Pop
Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Ellen S
ES
Vitetta