Photo-mediated green synthesis of silver and zinc oxide nanoparticles using aqueous extracts of two mangrove plant species, Heritiera fomes and Sonneratia apetala and investigation of their biomedical applications.
Green synthesis by using biological agents has been a simple and effective approach for the synthesis of various forms of nanoparticles. The present investigation was intended to synthesis Ag-NPs and ZnO-NPs under photo-condition using the aqueous extracts of two mangrove plants namely Heritiera fomes and Sonneratia apetala and evaluate their potential biomedical applications. The formation of nanoparticles in aqueous solution of H. fomes and S. apetala under exposure to sun light was validated by change in color and formation of monodispersed NPs with a narrow particle size distribution. Fourier transform infrared spectroscopy (FT-IR) reveals the presence of Oxime and other heterocyclic compounds to be the most probable compounds responsible for the reduction and stability of nanoparticles in the solutions. The synthesized NPs displayed moderate free radical scavenging properties. The anti-inflammatory potential of ZnO-NPs was recorded to be comparatively higher than that of Ag-NP with 79% and 69.1% respectively. The Ag-NPs with unique properties of inhibiting α-amylase (91.14% and 89.16%) were found to be significantly high indicating its antidiabetic property. The synthesized NPs showed varied zone of inhibition (9-16mm) against the tested microbial pathogens. The synthesized nanoparticles possess strong biological activities in terms of antioxidant, anti-inflammatory, antidiabetic and antibacterial, potentials which could be utilized in various biological applications by the cosmetic, food and biomedical industries.
Department of Biotechnology and Medical Engineering, NIT Rourkela, Rourkela 769008, Odisha, India.
Priyabrata
P
Thatoi
Department of Biotechnology, AMIT College, Khurda 752057, Odisha, India.
Rout George
RG
Kerry
AMITY Institute of Wildlife Science, Noida 201303, Uttar Pradesh, India.
Sushanto
S
Gouda
Research Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Ilsandong-gu, Gyeonggi-do 10326, Republic of Korea.
Gitishree
G
Das
Department of Biotechnology and Medical Engineering, NIT Rourkela, Rourkela 769008, Odisha, India. Electronic address: mondalkp@gmail.com.
Krishna
K
Pramanik
Department of Biotechnology, North Orissa University, Baripada 757003, Odisha, India.
Hrudayanath
H
Thatoi
Research Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Ilsandong-gu, Gyeonggi-do 10326, Republic of Korea. Electronic address: jkpatra@dongguk.edu.
Jayanta Kumar
JK
Patra
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D055772:Green Chemistry Technology; D007004:Hypoglycemic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D029561:Lythraceae / Q000737:chemistry; D019660:Malvaceae / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D055668:Photochemical Processes; D010936:Plant Extracts / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D014867:Water / Q000737:chemistry*; D015034:Zinc Oxide / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000975:Antioxidants; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D014867:Water; D012834:Silver; D015034:Zinc Oxide
Anti-inflammatory; Antimicrobial; Antioxidant; Aqueous plant extract, green synthesis; α-Amylase inhibition