Congenital anomalies following use of isotretinoin: Emphasis on its legal aspects.
We described a neonate with severe and multiple abnormalities following use of isotretinoin, in spite of the mother's previous knowledge of drug complications. Initial physical examination after delivery showed congenital absence of both eyes and both auricles as well as anal atresia and a cleft palate. Due to severe respiratory distress and atresia of the anus, the neonate was admitted to a neonatal intensive care unit and underwent reconstructive surgery. The drug should not have been used during pregnancy. Using this drug within pregnancy with awareness of its side effects may have legal consequences.
Forensic Medicine Department, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Naimeh
N
Farhidnia
Forensic Medicine Department, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Azadeh
A
Memarian
D000013:Congenital Abnormalities / Q000209:etiology*; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects* / Q000627:therapeutic use; D007603:Jurisprudence; D011247:Pregnancy; D055815:Young Adult
D015474:Isotretinoin
Congenital; anomalies; isotretinoin; legal