Watching a deep dive: Live imaging provides lessons about tooth invagination.
Invagination of epithelium into the surrounding mesenchyme is a critical step that marks the developmental onset of many ectodermal organs. In this issue, Ahtiainen et al. (2016. J. Cell. Biol. http://dx.doi.org/10.1083/jcb.201512074) use the mouse incisor as a model to advance our understanding of the cellular mechanisms underlying ectodermal organ morphogenesis.
Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA 94143 Program in Craniofacial Biology, University of California, San Francisco, San Francisco, CA 94143.
Amnon
A
Sharir
Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA 94143 Program in Craniofacial Biology, University of California, San Francisco, San Francisco, CA 94143 Department of Pediatrics and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 ophir.klein@ucsf.edu.
Ophir D
OD
Klein
D000818:Animals; D004848:Epithelium; D008648:Mesoderm; D051379:Mice; D038081:Organogenesis