Hypoalbuminemia and Malnutrition Associated With Cow's Milk Allergy: A Case Report.
BACKGROUND
Cow's milk allergy is the most common food allergy in children. Symptoms usually involve the skin and the gastrointestinal and respiratory tracts. Gastrointestinal tract manifestations of cow's milk allergy are nonspecific, and are the only type that can be diagnosed in all age groups. Here, we report a rare case of cow's milk allergy in an infant with hypoalbuminemia and malnutrition.


METHODS
A nine-month-old girl was admitted to Dr. Sami Ulus maternity and children's health and diseases training and research hospital, Ankara, Turkey, in September 2013, for weakness and swelling of the legs that had endured for two days. She had bilateral pretibial pitting (+2) edema. Laboratory data revealed albumin at 1.7 g/dL; serum Na, K, urea, creatinin, and alanine-aspartate aminotransferase levels were normal. Her urinary analysis did not reveal proteinuria. Stool samples were normal, and stool steatocrite was negative. Anti-gliadin, anti-endomysium, and anti-tissue transglutaminase antibodies were negative. Cow's milk allergy was diagnosed due to cow's milk-specific IgE and skin prick test results.


CONCLUSIONS
On rare occasions, cow's milk allergy presents with hypoalbuminemia. When diagnosis is delayed, this allergy may impair the growth and quality of life and may even be life-threatening.
Department of Pediatrics, Dr. Sami Ulus Maternity and Children's Health Education and Research Hospital, Ankara, Turkey.
Esma
E
Altinel Acoglu
Department of Pediatrics, Dr. Sami Ulus Maternity and Children's Health Education and Research Hospital, Ankara, Turkey.
Meltem
M
Akcaboy
Department of Pediatrics, Dr. Sami Ulus Maternity and Children's Health Education and Research Hospital, Ankara, Turkey.
Melahat
M
Melek Oguz
Department of Metabolism, Dr. Sami Ulus Maternity and Children's Health Education and Research Hospital, Ankara, Turkey.
Mustafa
M
Kilic
Department of Pediatrics, Dr. Sami Ulus Maternity and Children's Health Education and Research Hospital, Ankara, Turkey.
Pelin
P
Zorlu
Department of Pediatrics, Dr. Sami Ulus Maternity and Children's Health Education and Research Hospital, Ankara, Turkey.
Saliha
S
Senel
Cow’s Milk Allergy; Hypoalbuminemia; Infant; Malnutrition