Multimodal technique to eliminate humidity interference for specific detection of ethanol.
Multimodal electrochemical technique incorporating both open circuit potential (OCP) and amperometric techniques have been conceptualized and implemented to improve the detection of specific analyte in systems where more than one analyte is present. This approach has been demonstrated through the detection of ethanol while eliminating the contribution of water in a micro fuel cell sensor system. The sensor was interfaced with LMP91000 potentiostat, controlled through MSP430F5529LP microcontroller to implement an auto-calibration algorithm tailored to improve the detection of alcohol. The sensor was designed and fabricated as a three electrode system with Nafion as a proton exchange membrane (PEM). The electrochemical signal of the interfering phase (water) was eliminated by implementing the multimodal electrochemical detection technique. The results were validated by comparing sensor and potentiostat performances with a commercial sensor and potentiostat respectively. The results suggest that such a sensing system can detect ethanol at concentrations as low as 5ppm. The structure and properties such as low detection limit, selectivity and miniaturized size enables potential application of this device in wearable transdermal alcohol measurements.
Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States.
Ahmed Hasnain
AH
Jalal
Biomolecular Sciences Institute, Florida International University, Miami, FL 33174, United States.
Yogeswaran
Y
Umasankar
Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States.
Pablo J
PJ
Gonzalez
Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States.
Alejandro
A
Alfonso
Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States. Electronic address: sbhansa@fiu.edu.
Shekhar
S
Bhansali
D015374:Biosensing Techniques / Q000295:instrumentation*; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D000431:Ethanol / Q000032:analysis*; D005465:Fluorocarbon Polymers / Q000737:chemistry; D006801:Humans; D006813:Humidity; D057230:Limit of Detection; D008567:Membranes, Artificial; D015203:Reproducibility of Results; D012867:Skin / Q000737:chemistry; D014867:Water / Q000737:chemistry
D005465:Fluorocarbon Polymers; D008567:Membranes, Artificial; D014867:Water; C040402:perfluorosulfonic acid; D000431:Ethanol
Continuous monitoring; Ethanol; Fuel cell; Nafion; Potentiostat; Wearable