Surface-Selective Preferential Production of Reactive Oxygen Species on Piezoelectric Ceramics for Bacterial Killing.
Reactive oxygen species (ROS) can be used to kill bacterial cells, and thus the selective generation of ROS from material surfaces is an emerging direction in antibacterial material discovery. We found the polarization of piezoelectric ceramic causes the two sides of the disk to become positively and negatively charged, which translate into cathode and anode surfaces in an aqueous solution. Because of the microelectrolysis of water, ROS are preferentially formed on the cathode surface. Consequently, the bacteria are selectively killed on the cathode surface. However, the cell experiment suggested that the level of ROS is safe for normal mammalian cells.
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou 51006, China.
Guoxin
G
Tan
College of Materials Science and Engineering, South China University of Technology , Guangzhou 510641, China.
Shuangying
S
Wang
Department of Chemistry & Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma , 101 Stephenson Parkway, Norman, Oklahoma 73019, United States.
Ye
Y
Zhu
College of Materials Science and Engineering, South China University of Technology , Guangzhou 510641, China.
Lei
L
Zhou
College of Materials Science and Engineering, South China University of Technology , Guangzhou 510641, China.
Peng
P
Yu
College of Materials Science and Engineering, South China University of Technology , Guangzhou 510641, China.
Xiaolan
X
Wang
College of Materials Science and Engineering, South China University of Technology , Guangzhou 510641, China.
Tianrui
T
He
College of Materials Science and Engineering, South China University of Technology , Guangzhou 510641, China.
Junqi
J
Chen
Department of Chemistry & Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma , 101 Stephenson Parkway, Norman, Oklahoma 73019, United States.
Chuanbin
C
Mao
College of Materials Science and Engineering, South China University of Technology , Guangzhou 510641, China.
Chengyun
C
Ning
D000818:Animals; D000900:Anti-Bacterial Agents; D001419:Bacteria; D002516:Ceramics; D017382:Reactive Oxygen Species / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D017382:Reactive Oxygen Species
antibacterial mechanism; biocompatibility; piezoceramics; potassium sodium niobate; reactive oxygen