The Critical Role of Organic Chemistry in Drug Discovery.
Small molecules remain the backbone for modern drug discovery. They are conceived and synthesized by medicinal chemists, many of whom were originally trained as organic chemists. Support from government and industry to provide training and personnel for continued development of this critical skill set has been declining for many years. This Viewpoint highlights the value of organic chemistry and organic medicinal chemists in the complex journey of drug discovery as a reminder that basic science support must be restored.
Sokol Professor of Chemistry and Biochemistry Sokol Institute of Pharmaceutical Life Sciences Department of Chemistry and Biochemistry, Montclair State University , Montclair, New Jersey 07043, United States.
David P
DP
Rotella
D002625:Chemistry, Organic / Q000191:economics / Q000193:education; D002626:Chemistry, Pharmaceutical / Q000191:economics / Q000193:education; D055808:Drug Discovery / Q000379:methods; D055601:Organic Chemistry Phenomena; D012109:Research Support as Topic
AZT; drug discovery; organic chemistry; small molecules