Regioselective 1,4- and 1,6-Conjugate Additions of Grignard Reagent-Derived Organozinc(II)ates to Polyconjugated Esters.
Regioselective synthetic methods were developed for 1,4- and 1,6-conjugate additions of Grignard reagent-derived organozinc(II)ates to malonate-derived polyconjugated esters. By taking advantage of the tight ion-pair control of organozinc(II)ates, it was possible to switch between 1,4- and 1,6-conjugate additions by introducing a terminal ethoxy moiety in the conjugation.
Graduate School of Engineering, Nagoya University , Furo-cho, Chikusa, Nagoya 464-8603, Japan.
Manabu
M
Hatano
Graduate School of Engineering, Nagoya University , Furo-cho, Chikusa, Nagoya 464-8603, Japan.
Mai
M
Mizuno
Graduate School of Engineering, Nagoya University , Furo-cho, Chikusa, Nagoya 464-8603, Japan.
Kazuaki
K
Ishihara