Acute leukemia in children: A review of the current Indian data.
Acute leukemias are the most common diagnostic group of childhood cancer. This review summarizes the published literature on reported current outcomes of childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) from India. Overall survival in ALL ranged from 45% to 81% (commonly >60%) and event-free survival ranged from 41% to 70% (commonly >50%). Outcome data for AML was patchy with varying duration of follow-up, but it can be inferred that 50-80% of treated patients had experienced an event (toxic death, refractory disease or relapse). It is imperative that going forward focus should be on collaborative efforts, which promote treatment of patients on risk-stratified adapted protocols based on local infrastructure, improvement in supportive care and encourage prospective multi-center clinical trials.
Department of Medical Oncology, Max Super Speciality Hospital, New Delhi, India.
Ramandeep Singh
RS
Arora
Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.
Brijesh
B
Arora
Acute lymphoblastic leukemia; India; acute myeloid leukemia; child; outcomes; survival