A Review on the Terpenes from Genus Vitex.
The genus Vitex, which belongs to the Verbenaceae family, includes approximately 250 species. Some species of the genus Vitex have traditionally been used for the treatment of headaches, ophthalmodynia, coughs, asthma, premenopausal syndrome, etc. Chemical investigations indicate that the characteristic constituents of the genus Vitex are terpenes, and 210 of these compounds, including monoterpenoids, sesquiterpenoids, diterpenoids and triterpenoids, have been obtained from 12 species. Pharmacological studies had shown that these terpenes possess anti-inflammatory, antitumor, antibacterial, antioxidant activities, and so on. In this paper, the identity of these terpenes and their pharmacological effects are reviewed, which can provide references for further research regarding the chemistry and utilization of the Vitex species.
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. yaojinlong1992@163.com.|Key Laboratory of Formula of Traditional Chinese Medicine of Ministry of Education, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. yaojinlong1992@163.com.
Jin-Long
JL
Yao
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. fang_shiming@163.com.|Key Laboratory of Formula of Traditional Chinese Medicine of Ministry of Education, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. fang_shiming@163.com.
Shi-Ming
SM
Fang
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. lr_8000@163.com.|School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. lr_8000@163.com.
Rui
R
Liu
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. mahmood.obrobbey@gmail.com.
Mahmood Brobbey
MB
Oppong
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. liuwei628@sohu.com.|Key Laboratory of Formula of Traditional Chinese Medicine of Ministry of Education, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. liuwei628@sohu.com.
Er-Wei
EW
Liu
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. fgw1005@163.com.|Key Laboratory of Formula of Traditional Chinese Medicine of Ministry of Education, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. fgw1005@163.com.
Guan-Wei
GW
Fan
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. zhanghan0023@126.com.|Key Laboratory of Formula of Traditional Chinese Medicine of Ministry of Education, Tianjin University of Traditional Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China. zhanghan0023@126.com.
Han
H
Zhang
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D000893:Anti-Inflammatory Agents / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry*; D020950:Vitex / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D013729:Terpenes
Vitex genus; chemical constituents; pharmacological effects; terpenes