A Three-Component Reaction for the Synthesis of 1-Azabicyclo[3.1.0]hexane-3-enes.
A novel and simple synthesis of 1-azabicyclo[3.1.0]hexane-3-ene derivatives is described. The synthesis is carried out via a simple three-component reaction between aryl aldehydes, malononitrile, and hydroxylamine hydrochloride in water. Eco-friendliness, excellent product yields, short reaction time, inexpensive and readily available starting materials, and interesting reaction and products are the main advantages of this method.
Department of Chemistry, Payame Noor University , P.O. Box 19395-3697, Tehran, Iran.
Mahdi
M
Ghorbani
Department of Chemistry, Payame Noor University , P.O. Box 19395-3697, Tehran, Iran.
Bagher
B
Mohammadi
Department of Chemistry, Payame Noor University , P.O. Box 19395-3697, Tehran, Iran.
Mahnaz
M
Saraii
Department of Chemistry, Payame Noor University , P.O. Box 19395-3697, Tehran, Iran.
Bakhshali
B
Masoumi
Department of Chemistry, Payame Noor University , P.O. Box 19395-3697, Tehran, Iran.
Mojtaba
M
Abbasian
Department of Chemistry, University of Zanjan , P. O. Box 45195-313, Zanjan, Iran.
Ali
A
Ramazani
Faculty of Chemistry, University of Wrocław , 14 Joliot-Curie St., 50-383 Wrocław, Poland.
Katarzyna
K
Slepokura
Faculty of Chemistry, University of Wrocław , 14 Joliot-Curie St., 50-383 Wrocław, Poland.
Tadeusz
T
Lis