title: Comparison of two series of non-invasive instruments used for the skin physiological properties measurements: the DermaLab®from Cortex Technology vs. the series of detectors from Courage & Khazaka.
abstract: OBJECTIVE
  The detectors from Courage & Khazaka and DermaLab®from Cortex Technology were two series of the most commonly used non-invasive instruments for the skin physiological properties measurements. The aim of this study is to reveal the differences and correlations in measuring skin color, hydration, transepidermal water loss (TEWL), sebum and elasticity on the forearm or faces between two commercially available series of instruments.
  
  
  METHODS
  30 subjects were enrolled to be measured by the two series of instruments. The measurements by each series were performed on the left/right side of the body randomly. The hydration, sebum, elasticity and TEWL measurements were performed on different sites.
  
  
  RESULTS
  Positive correlations were found in the values of skin color, hydration, TEWL, sebum and visco-elasticity detected by the two series. The values related to skin firmness measured by the two instruments were statistically negative correlated. Contrary to the results in measuring the skin color, the detectors from Courage & Khazaka presented lower values of variation in measuring skin hydration and TEWL than those from DermaLab®.
  
  
  CONCLUSIONS
  The two series have significant correlations.The differences of the two series can be due either to differences in the design of the probe or left/right part of the body.
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: W
authors.initials: W
authors.lastname: Hua
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: L-M
authors.initials: LM
authors.lastname: Fan
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: R
authors.initials: R
authors.lastname: Dai
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: M
authors.initials: M
authors.lastname: Luan
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: H
authors.initials: H
authors.lastname: Xie
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: A-Q
authors.initials: AQ
authors.lastname: Li
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: L
authors.initials: L
authors.lastname: Li
mesh_terms: D003880:Dermatology / Q000295:instrumentation* / Q000379:methods; D055119:Elastic Modulus / Q000502:physiology; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D010808:Physical Examination / Q000295:instrumentation*; D015203:Reproducibility of Results; D012629:Sebum / Q000378:metabolism; D012680:Sensitivity and Specificity; D012869:Skin Absorption / Q000502:physiology; D012879:Skin Physiological Phenomena; D014870:Water Loss, Insensible / Q000502:physiology
keywords: 
  TEWL
  ; skin color; skin elasticity; skin hydration; skin sebum