title: Ultrasonographic Changes after Indirect Revascularization Surgery in Pediatric Patients with Moyamoya Disease.
abstract: The marked cerebral hypoperfusion of moyamoya disease (MMD) can be treated with encephaloduroarteriosynangiosis (EDAS), an indirect revascularization surgery. Collateral establishment after the surgery is a gradual process; thus, easy access to serial assessment is of great importance. We prospectively recruited 15 pediatric moyamoya patients who underwent EDAS surgeries on a total of 19 hemispheres. Ultrasonography of extracranial and intracranial arteries was performed pre-operatively and post-operatively at 1, 3 and 6 mo. Among the extracranial arteries, the superficial temporal artery had the most pronounced increase in flow velocity and decrease in flow resistance from 1 mo post-surgery (p < 0.01). Among the large intracranial arteries, a significant increase in peak systolic velocity was observed in the anterior cerebral artery from 3 mo post-surgery (p < 0.05). These findings indicate significant hemodynamic changes on ultrasonography in pediatric moyamoya patients after indirect revascularization surgery.
authors.affiliation: Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Shin-Joe
authors.initials: SJ
authors.lastname: Yeh
authors.affiliation: Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Sung-Chun
authors.initials: SC
authors.lastname: Tang
authors.affiliation: Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Li-Kai
authors.initials: LK
authors.lastname: Tsai
authors.affiliation: Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Ya-Fang
authors.initials: YF
authors.lastname: Chen
authors.affiliation: Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Hon-Man
authors.initials: HM
authors.lastname: Liu
authors.affiliation: Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Ying-An
authors.initials: YA
authors.lastname: Chen
authors.affiliation: Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Yu-Lin
authors.initials: YL
authors.lastname: Hsieh
authors.affiliation: Department of Neurosurgery, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Shih-Hung
authors.initials: SH
authors.lastname: Yang
authors.affiliation: Division of Clinical Psychology, Department of Occupational Therapy, College of Medicine, Chang-Gung University, Taoyuan, Taiwan.
authors.forename: Yu-Hsuan
authors.initials: YH
authors.lastname: Tien
authors.affiliation: Division of Clinical Psychology, Department of Occupational Therapy, College of Medicine, Chang-Gung University, Taoyuan, Taiwan.
authors.forename: Chi-Cheng
authors.initials: CC
authors.lastname: Yang
authors.affiliation: Department of Neurosurgery, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Meng-Fai
authors.initials: MF
authors.lastname: Kuo
authors.affiliation: Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: jsjeng@ntu.edu.tw.
authors.forename: Jiann-Shing
authors.initials: JS
authors.lastname: Jeng
mesh_terms: D000293:Adolescent; D000328:Adult; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000601:surgery*; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000601:surgery*; D002548:Cerebral Revascularization / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009072:Moyamoya Disease / Q000601:surgery*; D011182:Postoperative Care / Q000379:methods; D011300:Preoperative Care / Q000379:methods; D011446:Prospective Studies; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods*; D055815:Young Adult
keywords: Encephaloduroarteriosynangiosis; Indirect revascularization; Moyamoya disease; Pediatric stroke; Ultrasonography