title: Hepatocellular carcinoma in the adult Fontan patient.
abstract: In this study, we describe the case of a 36-year-old woman who was diagnosed with hepatocellular carcinoma on a background of Fontan procedure for tricuspid atresia. She had worsening heart failure in the months before presentation, and early investigations noted derangement in liver enzymes and hepatomegaly. Liver biopsy confirmed a hepatocellular carcinoma. Hepatocellular carcinoma is a rare but recognised consequence of cardiac cirrhosis in Fontan patients.
authors.affiliation: Department of Cardiology,Mayo Clinic,Scottsdale,Arizona,United States of America.
authors.forename: Michael R
authors.identifier: http://orcid.org/0000-0001-9048-5213
authors.initials: MR
authors.lastname: Conroy
authors.affiliation: Department of Cardiology,Mayo Clinic,Scottsdale,Arizona,United States of America.
authors.forename: Tabitha G
authors.initials: TG
authors.lastname: Moe
mesh_terms: D000328:Adult; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000209:etiology; D004452:Echocardiography; D017809:Fatal Outcome; D005260:Female; D018729:Fontan Procedure / Q000379:methods*; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000209:etiology; D011184:Postoperative Period; D018785:Tricuspid Atresia / Q000601:surgery*
keywords: Fontan; cirrhosis; hepatocellular; screening