title: A Review of HIV-Specific Patient-Reported Outcome Measures.
abstract: The use of patient-reported outcome (PRO) measures to provide added feedback to health providers is receiving interest as a means of improving clinical care and patient outcomes, and contributing to more patient-centered care. In human immunodeficiency virus (HIV), while PROs are used in research, their application in clinical practice has been limited despite their potential utility. PRO selection is an important consideration when contemplating their use. As past reviews of PROs in HIV have focused on particular areas (e.g. disability, satisfaction with care), a more comprehensive review could better inform on the available instruments and their scope. This article reviews HIV-specific PROs to produce an inventory and to identify the central concepts targeted over time. Seven databases were searched (HAPI, MEDLINE, PsychINFO, PubMed, EMBASE, CINAHL, Google Scholar), generating 14,794 records for evaluation. From these records, 117 HIV-specific PROs were identified and categorized based on a content analysis of their targeted concept: Health-Related Quality of Life (23; 20 %), ART and Adherence-Related Views and Experiences (19; 16 %), Healthcare-Related Views and Experiences (15; 13 %), Psychological Challenges (12; 10 %), Symptoms (12; 10 %), Psychological Resources (10; 9 %), HIV Self-Management and Self-Care (8; 7 %), HIV-Related Stigma (8; 7 %), Body and Facial Appearance (4; 3 %), Social Support (3; 3 %), Sexual and Reproductive Health (2; 2 %), and Disability (1; 1 %). This review highlights the variety and evolution of HIV-specific PROs, with the arrival of seven categories of PROs only after the advent of highly-active antiretroviral therapy. Our inventory also offers a useful resource. However, the interest of further HIV-specific PRO development should be explored in sexual health, which received little independent attention.
authors.affiliation: Chronic Viral Illness Service, Montreal Chest Institute, McGill University Health Centre, Local D02.4110, Glen Site, 1001 Décarie Boulevard, Montreal, QC, H4A 3J1, Canada. kimcengler@gmail.com.|Research Institute, McGill University Health Centre, Montreal, QC, Canada. kimcengler@gmail.com.|Department of Family Medicine, McGill University, Montreal, QC, Canada. kimcengler@gmail.com.
authors.forename: Kim
authors.initials: K
authors.lastname: Engler
authors.affiliation: Chronic Viral Illness Service, Montreal Chest Institute, McGill University Health Centre, Local D02.4110, Glen Site, 1001 Décarie Boulevard, Montreal, QC, H4A 3J1, Canada.|Department of Family Medicine, McGill University, Montreal, QC, Canada.
authors.forename: David
authors.initials: D
authors.lastname: Lessard
authors.affiliation: Chronic Viral Illness Service, Montreal Chest Institute, McGill University Health Centre, Local D02.4110, Glen Site, 1001 Décarie Boulevard, Montreal, QC, H4A 3J1, Canada.|Research Institute, McGill University Health Centre, Montreal, QC, Canada.|Department of Family Medicine, McGill University, Montreal, QC, Canada.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Lebouché
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000071066:Patient Reported Outcome Measures; D018802:Patient-Centered Care / Q000379:methods*; D011788:Quality of Life / Q000523:psychology*; D012648:Self Care / Q000523:psychology*; D057545:Social Stigma
chemical_list: D044966:Anti-Retroviral Agents