title: QTL editing confers opposing yield performance in different rice varieties.
abstract: Grain yield is one of the most important and complex trait for genetic improvement in crops; it is known to be controlled by a number of genes known as quantitative trait loci (QTLs). In the past decade, many yield-contributing QTLs have been identified in crops. However, it remains unclear whether those QTLs confer the same yield performance in different genetic backgrounds. Here, we performed CRISPR/Cas9-mediated QTL editing in five widely-cultivated rice varieties and revealed that the same QTL can have diverse, even opposing, effects on grain yield in different genetic backgrounds.
authors.affiliation: Key Laboratory of Plant Functional Genomics, Ministry of Education, Yangzhou University, Yangzhou 225009, China.|State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Shen
authors.affiliation: State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Fu
authors.affiliation: State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.affiliation: State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Crop and Nuclear Technology Utilization, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Plant Functional Genomics, Ministry of Education, Yangzhou University, Yangzhou 225009, China.
authors.forename: Changjie
authors.initials: C
authors.lastname: Yan
authors.affiliation: State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Qian
authors.affiliation: State Key Laboratory of Rice Biology, China National RiceResearch Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310006, China.
authors.forename: Kejian
authors.initials: K
authors.lastname: Wang
mesh_terms: D001483:Base Sequence; D000072669:Gene Editing; D017343:Genes, Plant; D005838:Genotype; D009154:Mutation / Q000235:genetics; D012275:Oryza / Q000235:genetics* / Q000254:growth & development*; D040641:Quantitative Trait Loci / Q000235:genetics*