title: [Nosocomial rotavirus gastroenteritis].
abstract: Rotavirus is the most common cause of gastroenteritis in children requiring hospitalization. It is a very resistant and contagious virus causing nosocomial gastroenteritis. In France, the vaccine against rotavirus has been available since 2006, but the vaccine is not recommended for infant vaccination. The aim of this retrospective study was to describe nosocomial rotavirus gastroenteritis (NRGE) and to assess its impact on children hospitalized in the General Pediatrics Department of Robert-Debré Hospital (Paris) between 1 January 2009 and 31 December 2013. We analyzed the demographic characteristics of children (age, term birth, underlying diseases) and the severity of the NRGE (oral or intravenous hydration), and assessed whether these children could benefit from vaccination against rotavirus.
  
  
  RESULTS
  One hundred thirty-six children presented nosocomial rotavirus infection, with an incidence of 2.5 NRGE per 1000 days of hospitalization. The incidence of NRGE was stable between 2009 and 2013 despite the introduction of specific hygiene measures. The average age of the children was 7 months (range: 0.5-111 months). Most often NRGE occurred in children hospitalized for respiratory diseases (65% of cases) and requiring prolonged hospitalization (median: 18 days). One-third of children were born premature (25%). Hydration was oral in 80 patients (59%), by intravenous infusion in 18 patients (13%), and intraosseous in one patient. Half of the patients were aged less than 5 months and could benefit from the protection afforded by vaccination.
  
  
  CONCLUSIONS
  NRGE are common. Rotavirus mass vaccination should have a positive impact on the incidence of NRGE by reducing the number of children hospitalized for gastroenteritis, therefore indirectly reducing the number of hospital cross-infections of hospitalized children who are too young to be vaccinated.
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Marinosci
authors.affiliation: Service de microbiologie, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Équipe d'hygiène hospitalière, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Doit
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Université Paris Diderot, Paris 7, 75019 Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Koehl
authors.affiliation: Équipe d'hygiène hospitalière, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: K
authors.initials: K
authors.lastname: Belhacel
authors.affiliation: Service de microbiologie, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Mariani Kurkdjian
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Université Paris Diderot, Paris 7, 75019 Paris, France.
authors.forename: I
authors.initials: I
authors.lastname: Melki
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Renaud
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Université Paris Diderot, Paris 7, 75019 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Lemaitre
authors.affiliation: Équipe d'hygiène hospitalière, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Ammar Khodja
authors.affiliation: Département d'informatique médical (DIM), hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Blachier
authors.affiliation: Service de microbiologie, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Université Paris Diderot, Paris 7, 75019 Paris, France; Inserm, IAME, UMR 1137, 75018 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Bonacorsi
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Université Paris Diderot, Paris 7, 75019 Paris, France; Inserm, ECEVE UMRS 1123, 75019 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Faye
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Université Paris Diderot, Paris 7, 75019 Paris, France; Inserm, ECEVE UMRS 1123, 75019 Paris, France. Electronic address: mathie.lorrot@aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Lorrot
mesh_terms: D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology*; D005260:Female; D005602:France / Q000453:epidemiology; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology*; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D012400:Rotavirus Infections / Q000453:epidemiology*