title: Mitral valve repair facilitated with transapical beating heart NeoChord implantation in a non-Hodgkin's lymphoma patient.
abstract: Elderly patients with severe hematological malignancies may require cardiac surgery. The combined impact of cardiopulmonary bypass (CPB) and surgical trauma is a potent inflammatory activator and is increased by intraoperative and postoperative complications. To avoid the adverse effects of CPB, minimally invasive off-pump techniques may be used in these patients. The transapical off-pump mitral valve intervention with NeoChord implantation (TOP-MINI) is a minimally invasive technique for mitral valve repair, which makes it possible to avoid the risks of CPB in selected patients, such as elderly, cancer or immunosuppressive patients. We report here the case of a 78-year-old male with B-cell non-Hodgkin's lymphoma, who presented with severe mitral regurgitation. The patient was successfully treated with the TOP-MINI procedure.
authors.affiliation: Department of Anaesthesiology and Reanimation, Antalya Training and Research Hospital, Antalya, Turkey. alisaitkavakli@hotmail.com.
authors.forename: Ali Sait
authors.initials: AS
authors.lastname: Kavakli
authors.affiliation: Department of Cardiovascular Surgery, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Raif Umut
authors.initials: RU
authors.lastname: Ayoglu
authors.affiliation: Department of Anaesthesiology and Reanimation, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Nilgun
authors.initials: N
authors.lastname: Kavrut Ozturk
authors.affiliation: Department of Cardiovascular Surgery, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Omer Haldun
authors.initials: OH
authors.lastname: Tekinalp
authors.affiliation: Department of Cardiology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Erkal
authors.affiliation: Department of Anaesthesiology and Reanimation, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Kerem
authors.initials: K
authors.lastname: Inanoglu
authors.affiliation: Department of Cardiovascular Surgery, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Emmiler
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000379:methods; D002315:Cardiopulmonary Bypass; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D016896:Treatment Outcome
keywords: Cardiac surgery; Minimal invasive; Mitral regurgitation; Non-Hodgkin’s lymphoma; Transapical mitral valve repair