title: Demographic, Clinical and Hematological Profile of Children with Bronchiolitis: A Comparative Study between Respiratory Synctial Virus [RSV] and [Non RSV] Groups.
abstract: BACKGROUND
  Acute bronchiolitis is one of major disease affecting the lower airways in infants and children with Respiratory Syncitial Virus (RSV) being most common causative organism accounting for 50%-80% of bronchiolitis cases.
  
  
  OBJECTIVE
  To analyse the demographic characteristics, clinical features and haematological profile of children with Bronchiolitis. To compare the findings of demographic characteristics, clinical features and haematological profile between RSV and Non -RSV bronchiolitis.
  
  
  METHODS
  This is a prospective study, conducted in a teritiary care center for 1 year period from Jan 2015 to Dec 2015. The demographic characteristics, clinical features and haematological profile of children aged between 1 month to 3 years who fulfilled the inclusion criteria were noted in predesigned proforma, nasopharyngeal swab was sent for RSV analysis and then the findings of the parameters were compared between the two groups of RSV bronchiolitis and Non RSV bronchiolitis.
  
  
  RESULTS
  Among 80 cases with 40 in each group, children below the age of 1year were affected more in RSV group, with male preponderance. Among the clinical features except that 89.7% of RSV cases had wheeze that was statistically significant with no difference in other features. Investigations showed no much difference in both the groups. Percentage of Non RSV subjects who received nebulisation with bronchodilators, steroid and antibiotic therapy were higher than RSV subjects. The hospital stay was significantly higher in RSV cases and none of the study participants met with mortality.
  
  
  CONCLUSIONS
  Children with RSV bronchiolitis had prolonged hospital stay compared to Non RSV group. Need for nebulisation with bronchodilators, steroids and antibiotic therapy was more in Non RSV group.
authors.affiliation: Assistant Professor, Department of Paediatrics, Chettinad Hospital and Research Institute , Kelambakkkam, Chennai, India .
authors.forename: Ganavi
authors.initials: G
authors.lastname: Ramagopal
authors.affiliation: Post Graduate Student, Department of Paediatrics, Chettinad Hospital and Research Institute , Kelambakkkam, Chennai, India .
authors.forename: Edin
authors.initials: E
authors.lastname: Brow
authors.affiliation: Assistant Professor, Department of Paediatrics, Chettinad Hospital and Research Institute , Kelambakkkam, Chennai, India .
authors.forename: Alexander
authors.initials: A
authors.lastname: Mannu
authors.affiliation: Professor, Department of Paediatrics, Chettinad Hospital and Research Institute , Kelambakkkam, Chennai, India .
authors.forename: Jaishree
authors.initials: J
authors.lastname: Vasudevan
authors.affiliation: Professor and Head of Department, Department of Paediatrics, Chettinad Hospital and Research Institute , Kelambakkkam, Chennai, India .
authors.forename: Lala
authors.initials: L
authors.lastname: Umadevi
keywords: Acute bronchiolitis; Haematological profile; Wheezing