title: Capnocytophaga ochracea-related Bacterium Bacteremia in a Hypertrophic Cardiomyopathy Patient without Neutropenia.
abstract: Gram-negative fusiform rods were detected in a blood culture obtained from a 63-year-old man who had been hospitalized for a long duration for severe heart failure. Although the organism could not be identified using a conventional method, it was finally identified as a bacterium of the Capnocytophaga ochracea group based on the results of biochemical testing, 16S rRNA sequencing and a matrix-assisted laser desorption ionization time-of-flight mass spectrometry analysis. Although neutropenic patients with poor oral hygiene are exclusively vulnerable to Capnocytophaga bacteremia, this case was unique because such predisposing conditions were not noted. A multi-centered investigation is warranted for a better understanding of this clinically rare, but potentially pathogenic organism.
authors.affiliation: Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Japan.
authors.forename: Shimpei
authors.initials: S
authors.lastname: Ito
authors.forename: Hideharu
authors.initials: H
authors.lastname: Hagiya
authors.forename: Keigo
authors.initials: K
authors.lastname: Kimura
authors.forename: Isao
authors.initials: I
authors.lastname: Nishi
authors.forename: Hisao
authors.initials: H
authors.lastname: Yoshida
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Kioka
authors.forename: Tomohito
authors.initials: T
authors.lastname: Ohtani
authors.forename: Osamu
authors.initials: O
authors.lastname: Yamaguchi
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Tanabe
authors.forename: Kazunori
authors.initials: K
authors.lastname: Tomono
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Sakata
mesh_terms: D016470:Bacteremia / Q000150:complications* / Q000382:microbiology*; D002206:Capnocytophaga; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications*; D016905:Gram-Negative Bacterial Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D012336:RNA, Ribosomal, 16S