title: Treatment of leakage via metallic stents placements after endoscopic full-thickness resection for esophageal and gastroesophageal junction submucosal tumors.
abstract: OBJECTIVE
  The objective of this study is to evaluate the feasibility and efficacy of endoscopic full-thickness resection (EFTR) and fully covered retrievable self-expandable metal stents (SEMSs) placement for this kind of tumors.
  
  
  METHODS
  A total of six consecutive patients, presenting with esophageal and GE junction SMTs, received EFTR and SEMSs placement at the our endoscopic center between January 2015 and June 2015. Their medical records were thoroughly investigated.
  
  
  RESULTS
  EFTR was performed successfully in all cases. The en bloc resection rate was 100%. The final pathological diagnoses were leiomyomas in all six cases. No patients developed delayed bleeding. SEMSs were placed immediately after EFTR during the same endoscopic session except patient #1. Complete healing of esophageal leakage after stent placement was achieved for 6/6 patients (100%) without the need for surgical interventions. Stent migration occurred in one patient. No residual tumor or tumor recurrence was observed during the follow-up period.
  
  
  CONCLUSIONS
  EFTR combined with fully covered retrievable self-expandable metallic stents placement is a feasible and effective new method for providing radical treatments for SMTs from the deep MP layer of esophagus and GE junction. Standardization of the procedure should be studied further.
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Liqing
authors.initials: L
authors.lastname: Yao
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Meidong
authors.initials: M
authors.lastname: Xu
authors.affiliation: b The Center for Advanced Endoscopy , Beth Israel Deaconess Medical Center, Harvard Medical School , Boston , MA , USA.
authors.forename: Tyler M
authors.initials: TM
authors.lastname: Berzin
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Quanlin
authors.initials: Q
authors.lastname: Li
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Weifeng
authors.initials: W
authors.lastname: Chen
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Jianwei
authors.initials: J
authors.lastname: Hu
authors.affiliation: c Department of Gastrointestinal Endoscopy , The First Affiliated Hospital of Nanjing Medical University , Nanjing , Jiangsu , PR China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Mingyan
authors.initials: M
authors.lastname: Cai
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Wenzheng
authors.initials: W
authors.lastname: Qin
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Jiaxin
authors.initials: J
authors.lastname: Xu
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Huang
authors.affiliation: a Endoscopy Center and Endoscopy Research Institute , Zhongshan Hospital, Fudan University , Shanghai , China.
authors.forename: Pinghong
authors.initials: P
authors.lastname: Zhou
mesh_terms: D000328:Adult; D002681:China; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects*; D004938:Esophageal Neoplasms / Q000601:surgery*; D004939:Esophageal Perforation / Q000209:etiology / Q000628:therapy*; D004943:Esophagogastric Junction / Q000473:pathology* / Q000601:surgery; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D007889:Leiomyoma / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011183:Postoperative Complications / Q000628:therapy*; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome
keywords: Submucosal tumors; endoscopic full-thickness resection; esophageal leakage; self-expandable metal stents