title: Nano-plasmonic-based structures for DNA sequencing.
abstract: We propose novel nano-plasmonic-based structures for rapid sequencing of DNA molecules. The optical properties of DNA nucleotides have notable differences in the ultraviolet (UV) region of light. Using nanopore, bowtie, and bowtie-nanopore compound structures, probable application of the surface plasmon resonance (SPR) in DNA sequencing is investigated by employing the discrete dipole approximation method. The effects of different materials like chromium (Cr), aluminum (Al), rhodium (Rh), and graphene (Gr) are studied. We show that for Cr/Al/Gr/Rh, the nucleotide presented shifts the SPR spectra for the nanopore 1/29/5/34 to 14/39/15/67 nm, bowtie 8/2/49/38 to 31/20/79/55 nm, and bowtie-nanopore compound 25/77/5/16 to 80/80/22/39 nm. The Cr-based compound structure shows excellent sensitivity and selectivity which can make it a promising methodology for DNA sequencing.
authors.forename: Bashir
authors.initials: B
authors.lastname: Fotouhi
authors.forename: Vahid
authors.initials: V
authors.lastname: Ahmadi
authors.forename: Vahid
authors.initials: V
authors.lastname: Faramarzi
mesh_terms: D001483:Base Sequence; D004247:DNA; D006108:Graphite / Q000737:chemistry; D058608:Nanopores; D017422:Sequence Analysis, DNA; D020349:Surface Plasmon Resonance / Q000379:methods*
chemical_list: D006108:Graphite; D004247:DNA