title: Myokines in Response to a Tournament Season among Young Tennis Players.
abstract: The study investigated changes in myokines, heat shock proteins, and growth factors in highly ranked, young, male tennis players in response to physical workload during the competitive season and their potential correlations with match scores. Blood collections were carried out at the beginning, the midpoint, and the end of the tournament season. Data analysis revealed a significant increase in interleukin 6 and its inverse correlation with the number of lost games (r = -0.45; 90% CI -0.06 to 0.77). Neither the irisin nor BDNF level changed notably, yet delta changes of irisin across the season significantly correlated with the number of games won. The concentration of HSP27 recorded a small increase (31.2%; 90% CI 10.7 to 55.5, most likely). A negative correlation was noted between IGF-1 and HSP27 concentration at baseline (-0.70 very high; 90% CI -0.89 to -0.31, very likely). At the end of the season IGF-1 correlated positively with the number of games won (r = 0.37 moderate, 90% CI -0.16 to 0.73, likely) but negatively with the number of games lost (r = -0.39, 90% CI -0.14 to -0.74, likely). In conclusion our data indicated that Il-6, irisin, and growth factor IGF-1 may modify overall performance during a long lasting season, expressed in the amount of games won or lost.
authors.affiliation: Department of Biochemistry, Institute of Sport, Warsaw, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Witek
authors.affiliation: Faculty of Physical Culture, University School of Physical Education Poznan, Gorzów Wielkopolski, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Żurek
authors.affiliation: Department of Physiology, Institute of Sport, Warsaw, Poland.
authors.forename: P
authors.identifier: 0000-0002-5570-9573
authors.initials: P
authors.lastname: Zmijewski
authors.affiliation: Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gdansk, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Jaworska
authors.affiliation: Department of Biomechanics, Institute of Sport, Warsaw, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Lipińska
authors.affiliation: Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gdansk, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Dzedzej-Gmiat
authors.affiliation: Department of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, Gdansk, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Antosiewicz
authors.affiliation: Department of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gdansk, Poland.
authors.forename: E
authors.identifier: 0000-0002-6361-0020
authors.initials: E
authors.lastname: Ziemann
mesh_terms: D000293:Adolescent; D000375:Aging / Q000276:immunology; D054874:Athletic Performance; D012090:Cumulative Trauma Disorders / Q000276:immunology*; D016207:Cytokines / Q000276:immunology*; D005353:Fibronectins / Q000097:blood / Q000276:immunology*; D006801:Humans; D015850:Interleukin-6 / Q000097:blood / Q000276:immunology*; D008297:Male; D009124:Muscle Proteins / Q000097:blood / Q000276:immunology*; D005082:Physical Exertion / Q000276:immunology; D013312:Stress, Physiological / Q000276:immunology; D013715:Tennis / Q000502:physiology*
chemical_list: D016207:Cytokines; C577593:FNDC5 protein, human; D005353:Fibronectins; C508600:IL6 protein, human; D015850:Interleukin-6; D009124:Muscle Proteins