title: [The effect of glial cells in the function and development of the nervous system in Caenorhabditis elegans].
abstract: There are three types of glial cells in Caenorhabditis elegans (C. elegans for short): sheath glia, socket glia and glutamate receptor glia. They are mainly located in four sensory organs including the amphid, the cephalic organ, the outer labial sensilla and the inner labial sensilla. C. elegans glial cells play key roles in dendrite extension, neurite guidance and extension, and are essential for synaptogenesis and maintain the normal morphology and the function of sensory nerve endings as well. A recent study shown that some nematode neurons are derived from the glial cells. Moreover, nematodes glial cells can directly modulate the function of sensory neurons. Some glial cells can also respond to certain external stimuli, such as mechanical stimulation, and adjust the accompanying neuronal activities.The article summarizes the progress on effects of nematodes glial cells on the nervous system development and function.
authors.affiliation: Institute of Neuroscience, Zhengjiang University School of Medicine, Hangzhou 310058, China.
authors.forename: X U
authors.initials: XU
authors.lastname: Yulan
authors.affiliation: Institute of Neuroscience, Zhengjiang University School of Medicine, Hangzhou 310058, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Yadan
authors.affiliation: Institute of Neuroscience, Zhengjiang University School of Medicine, Hangzhou 310058, China. kanglijun@zju.edu.cn.
authors.forename: Kang
authors.initials: K
authors.lastname: Lijun
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000254:growth & development*; D002633:Chemotaxis; D009457:Neuroglia / Q000166:cytology / Q000502:physiology*; D011984:Sensory Receptor Cells