title: Divergent Synthesis of Dihydroxanthene-Hemicyanine Fused Near-Infrared Fluorophores through the Late-Stage Amination of a Bifunctional Precursor.
abstract: A late-stage amination of a bifunctional dihydroxanthene (DHX) scaffold is reported to access a wide variety of new near-infrared (NIR) chromophores/fluorophores. The divergent approach allows the coupling of aliphatic and aromatic amines and readily provides molecular diversity shedding light on the structure-fluorescence relationship of this emerging class of NIR fluorophores.
authors.affiliation: Organic Chemistry, Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR) , 8 Biomedical Grove, Neuros, #07-01, Singapore, Singapore 138665.
authors.forename: Michelle Jui Hsien
authors.initials: MJ
authors.lastname: Ong
authors.affiliation: Organic Chemistry, Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR) , 8 Biomedical Grove, Neuros, #07-01, Singapore, Singapore 138665.
authors.forename: Rajavel
authors.initials: R
authors.lastname: Srinivasan
authors.affiliation: ICMUB, UMR 6302, CNRS, Univ. Bourgogne Franche-Comté, 9, Avenue Alain Savary, 21078 Dijon cedex, France.|Institut Universitaire de France , 103 Boulevard Saint-Michel, 75005 Paris, France.
authors.forename: Anthony
authors.initials: A
authors.lastname: Romieu
authors.affiliation: Organic Chemistry, Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR) , 8 Biomedical Grove, Neuros, #07-01, Singapore, Singapore 138665.
authors.forename: Jean-Alexandre
authors.initials: JA
authors.lastname: Richard