title: MYCOPLASMA PNEUMONIA-ASSOCIATED CHOROIDAL NEOVASCULARIZATION-BEVACIZUMAB INTRAVITREAL INJECTION AND LASER TREATMENT.
abstract: OBJECTIVE
  To report a rare case of bilateral subretinal granulomas with choroidal neovascularization after Mycoplasma pneumoniae atypical pneumonia.
  
  
  METHODS
  Presentation of a 7-year-old girl, who showed bilateral atypical subretinal granulomas with choroidal neovascularization. Visual acuity was 20/20 oculus dexter and 20/200 oculus sinister. Evaluation revealed a systemic Mycoplasma pneumoniae infection with pulmonary involvement. Successful ocular treatment was performed by intravitreal injection of Bevacizumab and laser photocoagulation.
  
  
  RESULTS
  Visual acuity was unchanged 36 months after treatment. No further subretinal lesions were seen oculus uterque.
  
  
  CONCLUSIONS
  To the best of their knowledge and according to literature this patient report is the first one of subretinal granuloma formation after pneumonia due to mycoplasma infection. Since Mycoplasma pneumoniae is a common pathogen, especially in children and young adults, it should be considered in the differential diagnosis of any febrile illness accompanied by ocular signs.
authors.affiliation: Departments of Ophthalmology, and.
authors.forename: Miltiadis
authors.initials: M
authors.lastname: Fiorentzis
authors.affiliation: Departments of Ophthalmology, and.
authors.forename: Barbara
authors.initials: B
authors.lastname: Käsmann-Kellner
authors.affiliation: Pediatrics & Neonatology, Saarland University Medical Center, Homburg/Saar, Germany.
authors.forename: Sascha
authors.initials: S
authors.lastname: Meyer
authors.affiliation: Departments of Ophthalmology, and.
authors.forename: Berthold
authors.initials: B
authors.lastname: Seitz
authors.affiliation: Departments of Ophthalmology, and.
authors.forename: Arne
authors.initials: A
authors.lastname: Viestenz
mesh_terms: D020533:Angiogenesis Inhibitors / Q000008:administration & dosage; D000068258:Bevacizumab / Q000008:administration & dosage*; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D002648:Child; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D058449:Intravitreal Injections; D053685:Laser Therapy / Q000379:methods*; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D040262:Receptors, Vascular Endothelial Growth Factor / Q000037:antagonists & inhibitors; D041623:Tomography, Optical Coherence; D014057:Tomography, X-Ray Computed; D014792:Visual Acuity; D014822:Vitreous Body / Q000473:pathology* / Q000601:surgery
chemical_list: D020533:Angiogenesis Inhibitors; D000068258:Bevacizumab; D040262:Receptors, Vascular Endothelial Growth Factor