title: Genome-Wide Comparison of Magnaporthe Species Reveals a Host-Specific Pattern of Secretory Proteins and Transposable Elements.
abstract: Blast disease caused by the Magnaporthe species is a major factor affecting the productivity of rice, wheat and millets. This study was aimed at generating genomic information for rice and non-rice Magnaporthe isolates to understand the extent of genetic variation. We have sequenced the whole genome of the Magnaporthe isolates, infecting rice (leaf and neck), finger millet (leaf and neck), foxtail millet (leaf) and buffel grass (leaf). Rice and finger millet isolates infecting both leaf and neck tissues were sequenced, since the damage and yield loss caused due to neck blast is much higher as compared to leaf blast. The genome-wide comparison was carried out to study the variability in gene content, candidate effectors, repeat element distribution, genes involved in carbohydrate metabolism and SNPs. The analysis of repeat element footprints revealed some genes such as naringenin, 2-oxoglutarate 3-dioxygenase being targeted by Pot2 and Occan, in isolates from different host species. Some repeat insertions were host-specific while other insertions were randomly shared between isolates. The distributions of repeat elements, secretory proteins, CAZymes and SNPs showed significant variation across host-specific lineages of Magnaporthe indicating an independent genome evolution orchestrated by multiple genomic factors.
authors.affiliation: Genomics Laboratory, Centre for Cellular and Molecular Platforms, National Centre for Biological Sciences, Bengaluru-560065, India.|Manipal University, Manipal-576104, India.
authors.forename: Meghana Deepak
authors.initials: MD
authors.lastname: Shirke
authors.affiliation: Genomics Laboratory, Centre for Cellular and Molecular Platforms, National Centre for Biological Sciences, Bengaluru-560065, India.|Marker Assisted Selection Laboratory, Department of Genetics and Plant Breeding, University of Agricultural Sciences, Bengaluru- 560065, India.
authors.forename: H B
authors.initials: HB
authors.lastname: Mahesh
authors.affiliation: Genomics Laboratory, Centre for Cellular and Molecular Platforms, National Centre for Biological Sciences, Bengaluru-560065, India.|Genomics Discovery Program, School of Conservation, Life Science and Health Sciences, TransDisciplinary University, Foundation of Revitalization of Local Health Traditions, Bengaluru- 560064, India.
authors.forename: Malali
authors.initials: M
authors.lastname: Gowda