title: Contrast-Induced Acute Kidney Injury.
abstract: Coronary angiography and percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber imaging. Despite advancements in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-induced acute kidney injury (CI-AKI) for a subgroup of patients at risk for this complication. There has been a consistent and graded signal of risk for associated outcomes including need for renal replacement therapy, rehospitalization, and death, according to the incidence and severity of CI-AKI. This paper reviews the epidemiology, pathophysiology, prognosis, and management of CI-AKI as it applies to the cardiac catheterization laboratory.
authors.affiliation: Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas; Baylor Heart and Vascular Institute, Dallas, Texas; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas; The Heart Hospital Baylor Plano, Plano, Texas. Electronic address: peteramccullough@gmail.com.
authors.forename: Peter A
authors.initials: PA
authors.lastname: McCullough
authors.affiliation: Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
authors.forename: James P
authors.initials: JP
authors.lastname: Choi
authors.affiliation: Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
authors.forename: Georges A
authors.initials: GA
authors.lastname: Feghali
authors.affiliation: Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Schussler
authors.affiliation: Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Stoler
authors.affiliation: Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas.
authors.forename: Ravi C
authors.initials: RC
authors.lastname: Vallabahn
authors.affiliation: Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas.
authors.forename: Ankit
authors.initials: A
authors.lastname: Mehta
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D000465:Algorithms; D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans
chemical_list: D003287:Contrast Media
keywords: cardiac catheterization; coronary angiography; iodine; percutaneous coronary intervention