title: Word catheter and marsupialisation in women with a cyst or abscess of the Bartholin gland (WoMan-trial): a randomised clinical trial.
abstract: OBJECTIVE
  To compare recurrence of a cyst or abscess of the Bartholin gland after surgical treatment using a Word catheter or marsupialisation.
  
  
  METHODS
  Multicentre, open-label, randomised controlled trial.
  
  
  METHODS
  Eighteen hospitals in the Netherlands and one hospital in England.
  
  
  METHODS
  Women with a symptomatic cyst or abscess of the Bartholin gland.
  
  
  METHODS
  Women were randomised to treatment with Word catheter or marsupialisation.
  
  
  METHODS
  The primary outcome was recurrence of the cyst or abscess within 1 year of treatment. The secondary outcomes included pain during and after treatment (measured on a 10-point scale), use of analgesics, and time from diagnosis to treatment. Analysis was by intention-to-treat. To assess whether marsupialisation would reduce the recurrence rate by 5% (from 20 to 15%) we needed to include 160 women (alpha error 0.05, beta error 0.2).
  
  
  RESULTS
  One hundred and sixty-one women were randomly allocated to treatment by Word catheter (n = 82) or marsupialisation (n = 79) between August 2010 and May 2014. Baseline characteristics were comparable. Recurrence occurred in 10 women (12%) allocated to Word catheter versus eight women (10%) allocated to marsupialisation: relative risk (RR) 1.1, 95% confidence interval (CI) 0.64-1.91; P = 0.70. Pain scores after treatment were also comparable. In the first 24 hours after treatment, 33% used analgesics in the Word catheter group versus 74% in the marsupialisation group (P < 0.001). Time from diagnosis to treatment was 1 hour for placement of Word catheter versus 4 hours for marsupialisation (P = 0.001).
  
  
  CONCLUSIONS
  In women with an abscess or cyst of the Bartholin gland, treatment with Word catheter and marsupialisation results in comparable recurrence rates.
  
  
  CONCLUSIONS
  Comparable recurrence rates for treatment of Bartholinic abscess/cyst with Word catheter and marsupialisation.
authors.affiliation: Department of Obstetrics and Gynaecology, Medical Spectrum Twente, Enschede, the Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Kroese
authors.affiliation: Department of Obstetrics and Gynaecology, Medical Spectrum Twente, Enschede, the Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: van der Velde
authors.affiliation: Department of Obstetrics and Gynaecology, Medical Centre Leeuwarden, Leeuwarden, the Netherlands.
authors.forename: L P
authors.initials: LP
authors.lastname: Morssink
authors.affiliation: Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, the Netherlands.|Department of Public Health, Academic Medical Centre, Amsterdam, the Netherlands.
authors.forename: M H
authors.initials: MH
authors.lastname: Zafarmand
authors.affiliation: Department of Obstetrics and Gynaecology, Maxima Medical Centre, Veldhoven, the Netherlands.
authors.forename: P
authors.initials: P
authors.lastname: Geomini
authors.affiliation: Department of Obstetrics and Gynaecology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
authors.forename: Pjm
authors.initials: P
authors.lastname: van Kesteren
authors.affiliation: Department of Obstetrics and Gynaecology, Saint Lucas Andreas Hospital, Amsterdam, the Netherlands.
authors.forename: C M
authors.initials: CM
authors.lastname: Radder
authors.affiliation: Department of Obstetrics and Gynaecology, Deventer Hospital, Deventer, the Netherlands.
authors.forename: L F
authors.initials: LF
authors.lastname: van der Voet
authors.affiliation: Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, the Netherlands.
authors.forename: Jpwr
authors.initials: J
authors.lastname: Roovers
authors.affiliation: Department of Obstetrics and Gynaecology, Antonius Hospital, Nieuwegein, the Netherlands.
authors.forename: Gcm
authors.initials: G
authors.lastname: Graziosi
authors.affiliation: Department of Obstetrics and Gynaecology, Flevoziekenhuis, Almere, the Netherlands.
authors.forename: W M
authors.initials: WM
authors.lastname: van Baal
authors.affiliation: Department of Obstetrics and Gynaecology, Amphia Hospital, Breda, the Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: van Bavel
authors.affiliation: Department of Obstetrics and Gynaecology, Maastricht University Medical Centre, Maastricht, the Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Catshoek
authors.affiliation: Department of Obstetrics and Gynaecology, University Medical Centre Groningen, Groningen, the Netherlands.
authors.forename: E R
authors.initials: ER
authors.lastname: Klinkert
authors.affiliation: Department of Obstetrics and Gynaecology, Vrije University Medical Centre, Amsterdam, the Netherlands.
authors.forename: Jaf
authors.initials: J
authors.lastname: Huirne
authors.affiliation: Department of Obstetrics and Gynaecology, Birmingham Women's Hospital, Birmingham, UK.
authors.forename: T J
authors.initials: TJ
authors.lastname: Clark
authors.affiliation: The Robinson Research Institute, School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, SA, Australia.
authors.forename: Bwj
authors.initials: B
authors.lastname: Mol
authors.affiliation: Department of Obstetrics and Gynaecology, Medical Spectrum Twente, Enschede, the Netherlands.
authors.forename: N
authors.initials: N
authors.lastname: Reesink-Peters
mesh_terms: D000038:Abscess / Q000601:surgery*; D000328:Adult; D001472:Bartholin's Glands / Q000601:surgery*; D002404:Catheterization / Q000295:instrumentation* / Q000379:methods; D057785:Catheters; D003560:Cysts / Q000601:surgery*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D016896:Treatment Outcome
keywords: Bartholin gland; Word catheter; marsupialisation