title: Continuous chromosomal instability in human pluripotent stem cells - the role of DNA replication.
abstract: Human pluripotent stem cells (hPSCs) frequently acquire chromosomal aberrations, including aneuploidy, during culture. Recently, we identified a replication stress-based mechanism leading to ongoing chromosomal instability in aneuploid hPSCs that may also operate during the initiation of instability in diploid cells.
authors.affiliation: Department of Genetics, The Hebrew University , Jerusalem, Israel.
authors.forename: Noa
authors.initials: N
authors.lastname: Lamm
authors.affiliation: Department of Genetics, The Hebrew University , Jerusalem, Israel.
authors.forename: Batsheva
authors.initials: B
authors.lastname: Kerem