title: Short-Term Perinatal Outcome among Term Infants with Prenatal Diagnosis of Large Abdominal Circumference.
abstract: BackgroundMeasuring fetal abdominal circumference (AC) prenatally is an effective tool for predicting neonatal weight and macrosomia. Data are lacking regarding the outcome of newborn infants with prenatal diagnosis of large AC.AimThe aim of this study was to evaluate early short-term neonatal outcome among term singleton newborn infants with prenatal diagnosis of large AC.MethodsRetrospective data were collected on 501 term infants with prenatal diagnosis of large AC (≥ 360 mm) and on matched controls, including information on maternal condition and on infant perinatal complications.ResultsIn compare with controls, the study group had higher incidence of macrosomia (188 [37.5%] vs. 18 [3.6%],p< 0.001), hypoglycemia (48 (9.6%) vs. 25 [5%],p= 0.007), and significant morbidity (49 [9.8%] vs. 28 [5.6%],p= 0.017) but without increased incidence of congenital malformations or other perinatal complications. Only among the macrosomic, study subgroup and their controls differences were recorded including hypoglycemia (17.6 vs. 4.8%,p< 0.001), need for oral glucose (11.2 vs. 2.7%,p= 0.002), significant morbidity (10.1 vs. 3.7%,p= 0.024), and hospitalization in special care unit (11.7 vs. 4.3%,p= 0.012).ConclusionPrelabor diagnosis of large AC mostly reflects the infant's high birth weight and macrosomia with the associated perinatal complications. Large AC by itself was not predictive of any congenital malformations or perinatal and postnatal complications.
authors.affiliation: Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Guy
authors.initials: G
authors.lastname: Steinberg-Barkon
authors.affiliation: Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Leah
authors.initials: L
authors.lastname: Leibovitch
authors.affiliation: Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Irit
authors.initials: I
authors.lastname: Schushan-Eisen
authors.affiliation: Department of Obstetrics, Sheba Medical Center, Tel HaShomer, Israel.
authors.forename: Liat
authors.initials: L
authors.lastname: Gindes
authors.affiliation: Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Tzipora
authors.initials: T
authors.lastname: Strauss
authors.affiliation: Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Ayala
authors.initials: A
authors.lastname: Maayan-Metzger
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging / Q000473:pathology*; D000653:Amniotic Fluid; D001724:Birth Weight; D016022:Case-Control Studies; D002585:Cesarean Section; D000013:Congenital Abnormalities / Q000453:epidemiology; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology*; D005767:Gastrointestinal Diseases / Q000453:epidemiology; D006331:Heart Diseases / Q000453:epidemiology; D006801:Humans; D007003:Hypoglycemia / Q000453:epidemiology*; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male; D009929:Organ Size; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging*; D012140:Respiratory Tract Diseases / Q000453:epidemiology; D012189:Retrospective Studies; D047929:Term Birth; D013997:Time Factors; D016216:Ultrasonography, Prenatal