title: Two New Clerodane Diterpenes from Tinospora sagittata.
abstract: Two new clerodane-type diterpenes, tinosporins C (1) and tinosporins D (2) were isolated from the stems ofTinospora sagittata(Oliv.), together with three known ones, columbin (3), tinophylloloside (4), and tinospinoside D (5). The structures of these compounds were determined on the basis of spectroscopic data interpretation, with that of the absolute configuration of compound1was assigned by experimental and calculated ECD spectra. The cytotoxicity and α-glucosidase inhibitory activities of isolated compounds were evaluated in vitro.
authors.affiliation: College of Plant Protection, Hunan Agricultural University, Changsha 410128, China. liguanhua@hunau.edu.cn.
authors.forename: Guanhua
authors.initials: G
authors.lastname: Li
authors.affiliation: College of Plant Protection, Hunan Agricultural University, Changsha 410128, China. dingwenb119@hunau.edu.cn.|Hunan Co-Innovation Center for Utilization of Botanical Functional Ingredients, Changsha 410128, China. dingwenb119@hunau.edu.cn.
authors.forename: Wenbing
authors.initials: W
authors.lastname: Ding
authors.affiliation: College of Plant Protection, Hunan Agricultural University, Changsha 410128, China. wanfanghao@caas.cn.|State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China. wanfanghao@caas.cn.
authors.forename: Fanghao
authors.initials: F
authors.lastname: Wan
authors.affiliation: College of Plant Protection, Hunan Agricultural University, Changsha 410128, China. liyouzhi@hunau.edu.cn.|Hunan Co-Innovation Center for Utilization of Botanical Functional Ingredients, Changsha 410128, China. liyouzhi@hunau.edu.cn.
authors.forename: Youzhi
authors.initials: Y
authors.lastname: Li
keywords: Tinospora sagittata; clerodane diterpenes; α-glucosidase inhibitory activity