title: Chondroblastic Variant of Osteosarcoma of Mandible: Report of a Rare Case.
abstract: Osteosarcoma (OS), a common malignant tumour of the long bones, is rarely seen in the craniofacial region (5-8%). Though it's aetiology is unknown, previous radiotherapy, Pagets disease, Retinoblastoma and benign bone lesions such as fibrous dysplasia are considered as predisposing factors. It is seen commonly in adults between the third and fourth decades of life, in the Gnathic location mandible. We report a rare case of chondroblastic variant of OS of the right mandible, in a 35-year-old male, who underwent right segmental mandibulectomy with fibular graft reconstruction and is having disease free survival one and half years post surgery. Craniofacial OSs, are considered a separate category in view of their low histologic grade, less frequent metastases and better prognosis. Hence the diagnosis of this variant is important. This case is reported because of its rarity and typical histopathological features.
authors.affiliation: Professor, Kempegowda Institute of Medical Sciences , Bangalore, Karnataka, India .
authors.forename: Kusuma
authors.initials: K
authors.lastname: Venkatesh
authors.affiliation: Post Graduate Cum Tutor, Kempegowda Institute of Medical Sciences , Bangalore, Karnataka, India .
authors.forename: Tushar
authors.initials: T
authors.lastname: Priyanka
authors.affiliation: Professor, Department of Pathology, Kempegowda Institute of Medical Sciences , Bangalore, Karnataka, India .
authors.forename: Niveditha Shankaran
authors.initials: NS
authors.lastname: Rukmini
authors.affiliation: Associate Professor Department of ENT, Kempegowda Institute of Medical Sciences , Bangalore, Karnataka, India .
authors.forename: Jagannath
authors.initials: J
authors.lastname: Bisanna
keywords: Craniofacial Osteosarcoma; Mandibulectomy; Prognosis