title: MRI-guided Wire Localization Surgical Biopsy in an Adolescent Patient with a Difficult to Diagnose Case of Lymphoma.
abstract: A 17-year-old previously healthy female presented with a progressive soft tissue infiltrative process involving the neck and thorax. Extensive diagnostic evaluation including multiple imaging, laboratory, and biopsy studies was nondiagnostic. Due to an urgent need to establish a diagnosis and several previous nondiagnostic biopsies, she was referred to interventional radiology for MRI-guided wire localization immediately prior to open surgical biopsy. Under general anesthesia, wires were placed in the areas of increased T2 signal within the bilateral splenius capitis muscles using intermittent MRI-guidance followed by immediate surgical biopsy down to the wires. Pathology confirmed the diagnosis of diffuse large B-cell lymphoma.
authors.affiliation: Department of Radiology, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, 55905, USA. Thompson.scott@mayo.edu.
authors.forename: Scott M
authors.initials: SM
authors.lastname: Thompson
authors.affiliation: Department of Radiology, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, 55905, USA.
authors.forename: Krzysztof R
authors.initials: KR
authors.lastname: Gorny
authors.affiliation: Department of Radiology, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, 55905, USA.
authors.forename: Danielle E
authors.initials: DE
authors.lastname: Jondal
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, 55905, USA.
authors.forename: Karen L
authors.initials: KL
authors.lastname: Rech
authors.affiliation: Division of Plastic and Reconstructive Surgery, Department of Surgery, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, 55905, USA.
authors.forename: Samir
authors.initials: S
authors.lastname: Mardini
authors.affiliation: Division of Vascular and Interventional Radiology, Department of Radiology, Mayo Clinic College of Medicine, 200 1st St SW, Rochester, MN, 55905, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Woodrum
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods*; D009333:Neck / Q000000981:diagnostic imaging / Q000473:pathology
keywords: Biopsy; Lymphoma; MRI-guided; Pediatric; Wire localization