title: Periodontal tissue repair after sealing of the gap in vertical root fracture.
abstract: The aim of this study was to determine whether sealing of fracture gap using adhesive resin through the root canal can prevent inflammation of periodontal tissue, and resealing the incompletely sealed fracture gap from outside can resolve such inflammation in experimentally created vertical root fractures. Vertical root fractures were created in incisor of beagles. In the experimental group, the fracture gap was sealed through the root canal with adhesive resin. After 5 weeks, sites with the clinical attachment level ≥4 mm were further divided randomly into the poor-replanting group and the poor-untreated group. In the poor-replanting group, the tooth was extracted and replanted after resealing the fracture gap with adhesive resin from the outer surface. Sites with clinical attachment level ≤3 mm after 5 weeks were considered as the satisfactory group. The poor-untreated group and the satisfactory group were subjected to no further treatment. The clinical attachment level was evaluated at baseline and after 2, 5, and 9 weeks. After 9 weeks, histological measurements were made to determine the length of the epithelial downgrowth and the area of alveolar bone resorption. The clinical attachment level and the area of bone resorption were significantly smaller in the poor-replanting group and the satisfactory group than in the poor-untreated group (p < 0.05). The results indicate the possibility that periodontal inflammation along the fracture line can be prevented and improved if the fracture gap is sealed.
authors.affiliation: Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Kita 13 Nishi 7 Kita-ku, Sapporo, 060-8586, Japan. sugaya@den.hokudai.ac.jp.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sugaya
authors.affiliation: Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Kita 13 Nishi 7 Kita-ku, Sapporo, 060-8586, Japan.
authors.forename: Mahito
authors.initials: M
authors.lastname: Tomita
authors.affiliation: Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Kita 13 Nishi 7 Kita-ku, Sapporo, 060-8586, Japan.
authors.forename: Youji
authors.initials: Y
authors.lastname: Motoki
authors.affiliation: Department of Dentistry, Dinajpur Medical College and Hospital, Dinajpur, 5200, Bangladesh.
authors.forename: Khurshiduz
authors.initials: K
authors.lastname: Zaman
authors.affiliation: Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Kita 13 Nishi 7 Kita-ku, Sapporo, 060-8586, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Miyaji
authors.affiliation: Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Kita 13 Nishi 7 Kita-ku, Sapporo, 060-8586, Japan.
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Kawanami
mesh_terms: D000818:Animals; D003487:Cyanoacrylates / Q000494:pharmacology*; D004195:Disease Models, Animal; D004285:Dogs; D007180:Incisor; D008297:Male; D008437:Maxilla; D010518:Periodontitis / Q000517:prevention & control*; D011897:Random Allocation; D014082:Tooth Fractures / Q000628:therapy*; D014092:Tooth Root / Q000293:injuries*
chemical_list: D003487:Cyanoacrylates; C538957:Super Bonder Instant Adhesive
keywords: Adhesive resin; Attachment level; Gap sealing; Periodontal inflammation; Vertical root fracture