title: Cerebrospinal Fluid Cytological Diagnosis in Multiple Myeloma With Leptomeningeal Involvement: A Report of Two Cases.
abstract: Multiple myeloma (MM) with central nervous system (CNS) infiltration is uncommon and the diagnosis is more complicated than that of MM. Here we report two cases of CNS MM that was diagnosed by cerebrospinal fluid cytology examination. Cerebrospinal fluid cytology examination can help to detect malignant cells and immunocytochemistry stain is of great value in identifying an unknown tumor. Diagn. Cytopathol. 2017;45:66-68. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
authors.forename: Haitao
authors.initials: H
authors.lastname: Ren
authors.affiliation: Department of Neurology, the Second Hospital of Hebei Medical University, Shijiazhuang, 050000, China.
authors.forename: Yueli
authors.initials: Y
authors.lastname: Zou
authors.affiliation: Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
authors.forename: Yanhuan
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Hemotology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Hemotology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Han
authors.affiliation: Department of Neurology, the Second Hospital of Hebei Medical University, Shijiazhuang, 050000, China.
authors.forename: Junying
authors.initials: J
authors.lastname: He
authors.affiliation: Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Guan
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000134:cerebrospinal fluid; D002555:Cerebrospinal Fluid / Q000166:cytology*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000134:cerebrospinal fluid / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: central nervous system; cerebrospinal fluid cytology; multiple myeloma