title: More than just tissue diagnosis in a patient with maxillofacial bony lesions and hypercalcemia.
abstract: Brown tumors are a definitive feature of hyperparathyroidism. They are well-demarcated osteolytic lesions commonly in the appendicular skeleton. Primary hyperparathyroidism is typically suggested by hypercalcemia and hypophosphatemia on routine labs. Much more rarely do these cases present with a craniofacial mass. Here we investigate a unique presentation of terminal stage primary hyperparathyroidism with a growing maxillary mass emphasizing the importance of a broad differential diagnosis and key diagnostic studies. Hyperparathyroidism can present in very unique ways. As otolaryngologists in the frontline, we must think beyond just tissue diagnoses so that appropriate and expedited care may be implemented. Laryngoscope, 127:1318-1321, 2017.
authors.affiliation: Department of Head and Neck Surgery , University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, U.S.A.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Vahabzadeh-Hagh
authors.affiliation: Department of Radiology , Olive-View University of California Los Angeles Medical Center, Sylmar, California, U.S.A.
authors.forename: Brian D
authors.initials: BD
authors.lastname: Zipser
authors.affiliation: Department of Pathology and Clinic Labs , Olive-View University of California Los Angeles Medical Center, Sylmar, California, U.S.A.
authors.forename: Hongying T
authors.initials: HT
authors.lastname: Tan
authors.affiliation: Department of Head and Neck Surgery , University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, U.S.A.
authors.forename: Austin Y
authors.initials: AY
authors.lastname: Hong
authors.affiliation: Department of Head and Neck Surgery , University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, U.S.A.
authors.forename: Jon Mallen-St
authors.initials: JM
authors.lastname: Clair
authors.affiliation: Department of Head and Neck Surgery , University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, U.S.A.
authors.forename: Bob B
authors.initials: BB
authors.lastname: Armin
mesh_terms: D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D049950:Hyperparathyroidism, Primary / Q000150:complications*; D008437:Maxilla; D008875:Middle Aged; D010002:Osteitis Fibrosa Cystica / Q000175:diagnosis* / Q000209:etiology; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000209:etiology
keywords: Brown tumor; hyperparathyroidism; osteitis fibrosa cystica