title: Seasonal variation of gastroprotective terpenoids in Maytenus robusta (Celastraceae) quantified by gas chromatography-flame ionization detection (GC-FID).
abstract: The triterpenes friedelin (1), β-friedelinol (2) and 3,15-dioxo-21α-hydroxyfriedelane (3) in the aerial parts of Maytenus robusta, a Brazilian medicinal plant with antiulcer potential, were seasonally quantified by gas chromatography flame-ionization detection (GC-FID) using an external standard. The method was found to be linear, precise and sensitive. Compounds 1 and 2 were found in M. robusta leaves and branches, with highest concentrations in the leaves collected in autumn, i.e. 3.21 ± 0.16 and 12.60 ± 1.49 mg g-1 dry weight of 1 and 2, respectively. On the other hand, compound 3 was found only in the branches, with the highest concentrations in winter and autumn (0.21 ± 0.01 and 0.20 ± 0.02 mg g-1). The results allow to define the optimal season and plant parts for the collection of M. robusta as a phytotherapeutic drug.
authors.forename: Tailyn
authors.initials: T
authors.lastname: Zermiani
authors.forename: Antonio A S
authors.initials: AA
authors.lastname: Junior
authors.forename: Renê A
authors.initials: RA
authors.lastname: Ferreira
authors.forename: Theodoro M
authors.initials: TM
authors.lastname: Wagner
authors.forename: Marina S
authors.initials: MS
authors.lastname: Machado
authors.forename: Valdir
authors.initials: V
authors.lastname: Cechinel-Filho
authors.forename: Rivaldo
authors.initials: R
authors.lastname: Niero
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D057230:Limit of Detection; D029755:Maytenus / Q000378:metabolism*; D012015:Reference Standards; D012621:Seasons; D013270:Stomach / Q000187:drug effects*; D013729:Terpenes / Q000494:pharmacology*
chemical_list: D013729:Terpenes