title: Resource allocation and compensation during development in holometabolous insects.
abstract: We provide an extensive review on current knowledge and future research paths on the topic of resource allocation and compensation during development in holometabolous insects, emphasizing the role of resource management during development, and how compensatory mechanisms may be acting to remediate nutritional deficiencies carried over from earlier stages of development. We first review resource allocation in "open" and "closed" developmental stages and then move on to the topic of modelling resource allocation and its trade-offs. In doing so, we review novel methodological developments such as response-surface methods and mixture experiments as well as nutritional geometry. We also dwell on the fascinating topic of compensatory physiology and behavior. We finish by discussing future research paths, among them the emerging field of nutrigenomics and gut microbiome, which will shed light into the yet poorly understood role of the symbiotic microbiota in nutrient compensation or assimilation.
authors.affiliation: Institute of Plant Protection, Dept. of Entomology, ARO, The Volcani Ctr., Beit Dagan 50250, Israel. Electronic address: nestel@agri.gov.il.
authors.forename: David
authors.initials: D
authors.lastname: Nestel
authors.affiliation: Laboratory of Entomology and Agricultural Zoology, Dept. of Agriculture Crop Production and Rural Environment, University of Thessaly, N. Ionia, Volos, Greece.
authors.forename: Nikos T
authors.initials: NT
authors.lastname: Papadopoulos
authors.affiliation: Instituto de Ecología, A.C., Clúster Científico y Tecnológico BioMimic®, Red de Manejo Biorracional de Plagas y Vectores, 91070 Xalapa, Veracruz, Mexico.
authors.forename: Carlos
authors.initials: C
authors.lastname: Pascacio-Villafán
authors.affiliation: Instituto de Ecología, A.C., Clúster Científico y Tecnológico BioMimic®, Red de Manejo Biorracional de Plagas y Vectores, 91070 Xalapa, Veracruz, Mexico.
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Righini
authors.affiliation: Instituto de Ecología, A.C., Clúster Científico y Tecnológico BioMimic®, Red de Manejo Biorracional de Plagas y Vectores, 91070 Xalapa, Veracruz, Mexico.
authors.forename: Alma R
authors.initials: AR
authors.lastname: Altuzar-Molina
authors.affiliation: Instituto de Ecología, A.C., Clúster Científico y Tecnológico BioMimic®, Red de Manejo Biorracional de Plagas y Vectores, 91070 Xalapa, Veracruz, Mexico.
authors.forename: Martín
authors.initials: M
authors.lastname: Aluja
mesh_terms: D000818:Animals; D007313:Insecta / Q000145:classification / Q000254:growth & development* / Q000502:physiology; D008954:Models, Biological
keywords: Compensatory physiology; Mixture experiments; Nutrigenomics; Nutritional geometry; Response-surface methods; Trade-off