title: Ampullary carcinosarcoma with osteosarcomatous, small cell neuroendocrine carcinoma and conventional adenocarcinoma components; First report.
abstract: Caracinosarcomas are tumours with diverse epithelial and mesenchymal differentiation. They most commonly occur in the female reproductive organs and upper aero digestive tract. They are relatively rare in the gastrointestinal tract and affect the oesophagus most commonly. Ampullary carcinosarcomas are exceptionally rare. We report a case of ampullary carcinosarcoma in a 67-year-old male, with osteosarcomatous, small cell carcinoma and conventional adenocarcinoma components. To the best of our knowledge, this is the first reported case of its kind.
authors.affiliation: Department of Histopathology, Sakra World Hospital, Sy No. 52/2 & 52/3, Deverbeesanahalli Varthur Hobli, Bangalore, 560103, India. Electronic address: drpallavirao@gmail.com.
authors.forename: Pallavi
authors.initials: P
authors.lastname: Rao
authors.affiliation: Department of Surgical Gastroenterology, Sakra World Hospital, Sy No. 52/2 & 52/3, Deverbeesanahalli Varthur Hobli, Bangalore, 560103 India, India.
authors.forename: Sadiq S
authors.initials: SS
authors.lastname: Sikora
authors.affiliation: Department of Radiology, Sakra World Hospital, Sy No. 52/2 & 52/3, Deverbeesanahalli Varthur Hobli, Bangalore, 560103, India.
authors.forename: Srikanth
authors.initials: S
authors.lastname: Narayanaswamy
authors.affiliation: Department of Histopathology, Sakra World Hospital, Sy No. 52/2 & 52/3, Deverbeesanahalli Varthur Hobli, Bangalore, 560103, India.
authors.forename: Nandita
authors.initials: N
authors.lastname: Ghosal
authors.affiliation: Department of Medical Gastroenterology, Sakra World Hospital, Sy No. 52/2 & 52/3, Deverbeesanahalli Varthur Hobli, Bangalore, 560103, India.
authors.forename: Dinesh
authors.initials: D
authors.lastname: Kini
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D014670:Ampulla of Vater / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000032:analysis*; D018278:Carcinoma, Neuroendocrine / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000473:pathology; D002296:Carcinosarcoma / Q000473:pathology*; D003138:Common Bile Duct Neoplasms / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012516:Osteosarcoma / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor
keywords: Adenocarcinoma; Ampulla of vater; Carcinosarcoma; Osteosarcoma; Small cell carcinoma