title: Copper deficiency as a cause of neutropenia in a case of coeliac disease.
abstract: We report a 17 year-old male patient, who presented with chronic diarrhoea, progressive pallor, short stature, anaemia (haemoglobin of 4.9 g/dL) and neutropenia and was diagnosed as coeliac disease. His neutropenia did not respond to 8 months of gluten-free diet, iron, folic acid and vitamin B12 therapy. So we suspected copper deficiency and his serum copper levels were tested, which was low. His neutrophil counts normalised after 2 months of copper supplementation. Hence we concluded that the cause of neutropenia in our case was copper deficiency.
authors.affiliation: Department of Paediatrics, All India Institute of Medical Sciences, Jodhpur, India.
authors.forename: Daisy
authors.initials: D
authors.lastname: Khera
authors.affiliation: Department of Paediatrics, All India Institute of Medical Sciences, Jodhpur, India.
authors.forename: Baldev
authors.initials: B
authors.lastname: Sharma
authors.affiliation: Department of Paediatrics, All India Institute of Medical Sciences, Jodhpur, India.
authors.forename: Kuldeep
authors.identifier: http://orcid.org/0000-0002-9375-3233
authors.initials: K
authors.lastname: Singh
mesh_terms: D000293:Adolescent; D000740:Anemia / Q000209:etiology; D002446:Celiac Disease / Q000097:blood / Q000150:complications*; D003300:Copper / Q000097:blood / Q000172:deficiency*; D003967:Diarrhea / Q000209:etiology; D055050:Diet, Gluten-Free; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000097:blood / Q000209:etiology*
chemical_list: D003300:Copper