title: A General Pediatrics and Integrative Medicine Approach to Pervasive Refusal Syndrome: A Case Report.
abstract: Pervasive refusal syndrome (PRS) describes children with social withdrawal who become unable to walk, eat, or care for themselves. This case report examines whether an integrative medicine approach is useful for treating PRS.
  
  
  
  A seven-year-old girl with symptoms most consistent with PRS and depression was admitted to a pediatric ward in Germany that integrates conventional pediatric and psychosomatic care with anthroposophic medicine. She was integrated into the structured activities of the ward and received massages, movement therapy, and color light therapy. Her parents were fully integrated into her care. After four weeks, she talked again, showed increased appetite, and supported herself when moved passively. She made a full recovery within four weeks after hospital discharge.
  
  
  
  Integration of parents and an integrative medicine approach providing a variety of comforting sensory experiences was helpful for this patient with PRS.
authors.affiliation: Researcher at the ARCIM Institute in Filderstadt, Germany, and an Attending Physician in the Department of Pediatrics at Fribourg Hospital in Switzerland. tido.von.schoenangerer@gmail.com.
authors.forename: Tido
authors.initials: T
authors.lastname: Von Schoen-Angerer
authors.affiliation: Pediatrician at the Filderklinik in Filderstadt, Germany. e.helmschmidt@filderklinik.de.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Helmschmidt
authors.affiliation: Head of the Pediatric Neurology unit at the Filderklinik in Filderstadt, Germany. r.madeleyn@filderklinik.de.
authors.forename: René
authors.initials: R
authors.lastname: Madeleyn
authors.affiliation: General Practitioner in private practice in Hannover, Germany. reinhard.kindt@posteo.de.
authors.forename: Reinhard
authors.initials: R
authors.lastname: Kindt
authors.affiliation: Chief of the Department of Child and Adolescent Psychiatric at Children's Hospital Auf der Bult in Hannover, Germany. moeller@hka.de.
authors.forename: Christoph
authors.initials: C
authors.lastname: Möller
authors.affiliation: Senior Researcher at the Institute for Applied Epistemology and Medical Methodology at the University of Witten/Herdecke in Freiburg im Breisgau, Germany. gunver.kienle@ifaemm.de.
authors.forename: Gunver Sophia
authors.initials: GS
authors.lastname: Kienle
authors.affiliation: Scientific Director at the ARCIM Institute in Filderstadt, Germany, and a Researcher in the Department of Pediatrics at the University Hospital Tübingen, Germany. j.vagedes@arcim-institute.de.
authors.forename: Jan
authors.initials: J
authors.lastname: Vagedes
mesh_terms: D002389:Catatonia / Q000628:therapy*; D002648:Child; D000529:Complementary Therapies; D003863:Depression / Q000628:therapy; D003866:Depressive Disorder / Q000628:therapy*; D001068:Feeding and Eating Disorders / Q000628:therapy*; D005260:Female; D005858:Germany; D006801:Humans; D055048:Integrative Medicine; D010372:Pediatrics; D002666:Psychology, Child; D013577:Syndrome