title: Pulse Wave Analysis by Applanation Tonometry for the Measurement of Arterial Stiffness.
abstract: The aim of our study was to investigate the association between pulse wave velocity (PWV) and pulse wave analysis (PWA)-derived measurements for the evaluation of arterial stiffness. A total of 20 (7 male and 13 female) healthy, non-smoking individuals, with mean age 31 ± 12years were included. PWV and PWA measurements were performed using a SphygmoCor apparatus (Atcor Medical Blood Pressure Analysis System, Sydney Australia). PWV significantly correlated with all central aortic haemodynamic parameters, especially with pulse pressure (PP) (p < 0.0001), augmentation index corrected for 75 pulses/min (AI75) (p = 0.035) and augmentation pressure (AP) (p = 0.005). Male subjects presented significantly higher PWV compared with females (p = 0.03), while there were no differences in PP, AP and AI75. In conclusion, PWA is strongly correlated with PWV as a method for the evaluation of arterial stiffness.
authors.affiliation: Joslin Diabetes Centre, Harvard Medical School, Boston, MA, USA.
authors.forename: John
authors.initials: J
authors.lastname: Doupis
authors.affiliation: Diabetes Centre, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Papanas
authors.affiliation: Joslin Diabetes Centre, Harvard Medical School, Boston, MA, USA.
authors.forename: Alison
authors.initials: A
authors.lastname: Cohen
authors.affiliation: Joslin Diabetes Centre, Harvard Medical School, Boston, MA, USA.
authors.forename: Lyndsay
authors.initials: L
authors.lastname: McFarlan
authors.affiliation: Joslin Diabetes Centre, Harvard Medical School, Boston, MA, USA.
authors.forename: Edward
authors.initials: E
authors.lastname: Horton
keywords: Applanation tonometry; Arterial stiffness; Pulse wave analysis; Pulse wave velocity