title: Current biomarkers of invasive sporadic pituitary adenomas.
abstract: Though pituitary adenomas (PA) are considered benign, some of them exhibit invasive behaviors such as recurrence and low rate of total surgical resection. Reliable prognostic biomarkers for invasive PA are highly desired; however they remain to be identified. In this review, we summarize the current controversial findings of biomarkers for invasive sporadic PA, and we discuss the possible reasons for the controversies.
authors.affiliation: Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, 183, Xinqiao Main Street, Shapingba District, Chongqing, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, 183, Xinqiao Main Street, Shapingba District, Chongqing, China.
authors.forename: Song
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Biology and Biochemistry, University of Houston, Houston, TX, USA.
authors.forename: Weihua
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, 183, Xinqiao Main Street, Shapingba District, Chongqing, China.
authors.forename: Zhenle
authors.initials: Z
authors.lastname: Zang
authors.affiliation: Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, 183, Xinqiao Main Street, Shapingba District, Chongqing, China.
authors.forename: Jintao
authors.initials: J
authors.lastname: Hu
authors.affiliation: Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, 183, Xinqiao Main Street, Shapingba District, Chongqing, China. Electronic address: yanghui64@hotmail.com.
authors.forename: Hui
authors.initials: H
authors.lastname: Yang
mesh_terms: D000236:Adenoma / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000502:physiology; D003940:Diagnostic Techniques, Endocrine / Q000639:trends; D006801:Humans; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D010911:Pituitary Neoplasms / Q000473:pathology*; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor
keywords: Adénome hypophysaire; Biomarkers; Biomarqueurs; Invasiveness; Invasivité; Pituitary adenoma