title: [Analysis of the 2015 British guidelines on the prevention and management of tumor lysis syndrome].
abstract: Whether it appears spontaneously or is induced by therapy, the tumor lysis syndrome is responsible for a massive release of ions and puric bases degradation of products in the circulation exceeding the renal excretion capacity. Some, such as uric acid, xanthine, and calcium phosphate, can precipitate in the renal tubules or parenchyma. It must be known to any practitioner supporting patients with hematologic malignancies, mainly high-grade but also some solid tumors. The 2015 publication of the British recommendations pertaining to patients suffering from hematological diseases should be broadcast. The main goal of treatment is to prevent the occurrence of renal dysfunction associated with heavy morbidity and mortality, either for his own conduct or consequences on obtaining a good tumor response. Some items proposed for the care, whether curative or preventive, should be discussed or detailed, which is the subject of this paper.
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: A
authors.initials: A
authors.lastname: Dupré
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: C
authors.initials: C
authors.lastname: Mousseaux
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: A
authors.initials: A
authors.lastname: Bouguerba
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: S
authors.initials: S
authors.lastname: Ayed
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: J
authors.initials: J
authors.lastname: Barchazs
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: M
authors.initials: M
authors.lastname: Boukari
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: D
authors.initials: D
authors.lastname: Goldgran-Toledano
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
authors.forename: C
authors.initials: C
authors.lastname: Bornstain
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France. Electronic address: frncsvncnt@aol.com.
authors.forename: F
authors.initials: F
authors.lastname: Vincent
authors.affiliation: Réanimation polyvalente, Groupe Hospitalier intercommunal Le Raincy-Montfermeil, 10, avenue du Général-Leclerc, 93370 Montfermeil, France.
mesh_terms: D000328:Adult; D000493:Allopurinol / Q000627:therapeutic use; D002648:Child; D019337:Hematologic Neoplasms / Q000150:complications / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D009369:Neoplasms / Q000150:complications / Q000453:epidemiology / Q000628:therapy; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D015275:Tumor Lysis Syndrome / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*; D006113:United Kingdom; D014527:Uric Acid / Q000652:urine
chemical_list: D014527:Uric Acid; D000493:Allopurinol
keywords: Acute kidney injury; Guidelines; Insuffisance rénale aiguë; Intensive care; Rasburicase; Recommandations; Réanimation; Syndrome de lyse tumorale; Tumor lysis syndrome