title: Patterns of Systemic Hypertension among Adults with Perinatally Acquired HIV.
abstract: Patients with perinatally acquired HIV may be at risk for the development of age-related non-AIDS diseases. The primary aim of this study was to describe patterns of systemic hypertension among a cohort of adults (≥18 years) with perinatally acquired HIV. A retrospective cohort study was conducted among adults (≥18 years) with perinatally acquired HIV infection. Primary outcomes included documentation of systemic hypertension as well as several additional non-AIDS-associated illnesses. Systemic hypertension incidence rates and rate ratios (RRs) were calculated among groups aged ≥18 and <18 years at the time of hypertension diagnosis. The overall prevalence of hypertension in the cohort (N = 109) was 26.6%, and the incidence rate of hypertension was significantly higher among those aged ≥18 years compared to those who are aged <18 years at the time of diagnosis (RR: 10.0, CI: 7.29-13.71). By multivariable analysis, only coexisting renal disease was associated with an increased risk of hypertension diagnosis.
authors.affiliation: 1 Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Patrick
authors.initials: P
authors.lastname: Ryscavage
authors.affiliation: 1 Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Macharia
authors.affiliation: 1 Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Lino R
authors.initials: LR
authors.lastname: Trinidad
authors.affiliation: 2 Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Susan
authors.initials: S
authors.lastname: Lovelace
authors.affiliation: 2 Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Vicki
authors.initials: V
authors.lastname: Tepper
authors.affiliation: 1 Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Redfield
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology / Q000635:transmission; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology; D015994:Incidence; D007223:Infant; D018445:Infectious Disease Transmission, Vertical; D015995:Prevalence; D012189:Retrospective Studies; D055815:Young Adult
keywords: HIV; adult; hypertension; perinatal