title: Comparison of the Chemical Profiles and Antioxidant and Antidiabetic Activities of Extracts from Two Ganoderma Species (Agaricomycetes).
abstract: The objective of this study was to compare the mycochemical profiles, antioxidant activities, and antidiabetic effects of 2 species of genus Ganoderma, the red lingzhi (G. lucidum) and purple lingzhi (G. sinense) mushrooms. In Chinese medicinal practice, hot water and ethanol are used as solvents to extract samples. In this study, a total of 4 extracts (ethanol and hot water extracts from G. lucidum and G. sinense) were prepared for further assays. Hot water extracts presented much higher values for total phenolic content and ferric-reducing antioxidant power than the ethanol extracts. Ethanol (70%) extract of G. lucidum had the strongest α-glycosidase inhibitory capacity, but the lingzhi polysaccharides showed no inhibitory effect. It also had the largest amount of total ganoderic acids. The results indicated that ethanol extracts from both G. lucidum and G. sinense showed better antidiabetic effects than the hot water extracts. Ganoderic acids, rather than polysaccharides, may contribute the antidiabetic effects of both the Ganoderma species.
authors.affiliation: Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, China.
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Tang
authors.affiliation: Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, China.
authors.forename: Weixi
authors.initials: W
authors.lastname: Cai
authors.affiliation: Programme of Food Science and Technology Div. of Science and Technology, Beijing Normal University, Hong Kong Baptist University, United International College SAR of PRC.
authors.forename: Baojun
authors.initials: B
authors.lastname: Xu
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D036681:Fluorescence Recovery After Photobleaching; D032902:Ganoderma / Q000737:chemistry* / Q000145:classification*; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000494:pharmacology*; D010851:Picrates / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry / Q000145:classification; D013045:Species Specificity; D014315:Triterpenes / Q000737:chemistry / Q000145:classification
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D007004:Hypoglycemic Agents; D010851:Picrates; D011134:Polysaccharides; D014315:Triterpenes; C004931:1,1-diphenyl-2-picrylhydrazyl; D006026:Glycoside Hydrolases