title: Guillain-Barré syndrome: What have we learnt during one century? A personal historical perspective.
abstract: We are approaching the centenary of the first description of Guillain-Barré syndrome. The past 30 years had witnessed an amazing progress in the understanding of the immunological and pathological mechanisms of this disorder. We now recognize that Guillain-Barré syndrome is remarkably heterogeneous and under this umbrella term are several variants and subtypes with distinct clinical, electrophysiological and immunopathological features. This review is a historical journey, through a personal perspective, following the milestones that led to the current substantial knowledge of Guillain-Barré syndrome.
authors.affiliation: Department of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", Via Luigi Polacchi, 66100 Chieti, Italy. Electronic address: uncini@unich.it.
authors.forename: A
authors.initials: A
authors.lastname: Uncini
mesh_terms: D004568:Electrodiagnosis; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000266:history / Q000473:pathology / Q000628:therapy*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans
keywords: Acute inflammatory demyelinating neuropathy; Acute motor axonal neuropathy; Anti-gangliosides antibodies; Campylobacter jejuni; Electrodiagnosis; Guillain-Barré syndrome