title: The pCONus Device in Treatment of Wide-necked Aneurysms : Technical and Midterm Clinical and Angiographic Results.
abstract: OBJECTIVE
  A variety of devices for treatment of wide-necked bifurcation aneurysms are emerging. Here we report our results using the new pCONus device with special emphasis on the morphological and anatomical requirements for successful implantation.
  
  
  METHODS
  In this study we treated 21 patients with 22 aneurysms by endovascular interventions. After providing informed consent, patients were included according to the following criteria: aneurysm dome to neck ratio <2 or neck diameter >4 mm. The primary end points for clinical safety were the absence of death, absence of major or minor stroke and absence of transient ischemic attack.
  
  
  RESULTS
  A total of 22 aneurysms in 21 patients were treated with pCONus-assisted coiling. In 19 patients harboring 20 aneurysms the implantation of the device was successful and these aneurysms showed an adequate occlusion after 6 months in 95 %. The complication rate was low (5 %) with one case of minor neurological stroke. Analysis of the data showed that the difference in aneurysm angulation between successful (mean 45°) and failed implantations (mean 71.5°) was highly significant.
  
  
  CONCLUSIONS
  Use of the pCONus device and coiling in wide-necked bifurcation aneurysms is safe and provides good occlusion rates but might be limited by the angulation between the aneurysm and the parent vessel.
authors.affiliation: Department of Neuroradiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
authors.forename: C
authors.identifier: http://orcid.org/0000-0003-3642-350X
authors.initials: C
authors.lastname: Ulfert
authors.affiliation: Department of Neuroradiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Pfaff
authors.affiliation: Department of Neurology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Schönenberger
authors.affiliation: Department of Neurology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Bösel
authors.affiliation: Department of Neuroradiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Herweh
authors.affiliation: Department of Neuroradiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Pham
authors.affiliation: Department of Neuroradiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Bendszus
authors.affiliation: Department of Neuroradiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. markus.moehlenbruch@med.uni-heidelberg.de.
authors.forename: M
authors.initials: M
authors.lastname: Möhlenbruch
mesh_terms: D000328:Adult; D000368:Aged; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic; D005858:Germany; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
keywords: Aneurysm; Bifurcation; Coiling; Device; Stent