title: Parity and serum lipid levels: a cross-sectional study in chinese female adults.
abstract: Reproductive factors have been shown to correlate with lipid metabolism. The aim of this study was to investigate the relationship between parity and serum lipid levels in community-based Chinese female adults. A total of 4,217 female participants were enrolled. Parity was recorded according to questionnaire and serum lipid profile, including triglycerides (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein cholesterol (HDL-C), was measured. Logistic regression models were used to analyze the association of parity to serum lipid levels, while adjusting for demographics and metabolic risk factors. Parity in this population ranged from 0 to 7. After adjusting for potential confounders, it indicated that females with more than 2 parities appeared to be less likely to suffer from abnormal serum TC level compared with nulliparae (parity = 2, odds ratio (OR) = 0.457, 95% confidence interval (CI) = 0.284-0.736; parity ≥ 3, OR = 0.363, 95% CI = 0.202-0.653). These findings suggested that parity could correlate with lipid metabolism in Chinese women. Individuals with higher parity appeared to have a lower total cholesterol in blood.
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
authors.forename: Haichen
authors.initials: H
authors.lastname: Lv
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: School of Public Health, Dalian Medical University, Dalian, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wu
authors.affiliation: Beijing Recdata Technology Co. Ltd., Beijing, China.
authors.forename: Henghui
authors.initials: H
authors.lastname: Liu
authors.affiliation: Beijing Municipal Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing, China.
authors.forename: Youxin
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Beijing Recdata Technology Co. Ltd., Beijing, China.
authors.forename: Yuanming
authors.initials: Y
authors.lastname: Pan
authors.affiliation: Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
authors.forename: Yunlong
authors.initials: Y
authors.lastname: Xia
mesh_terms: D000328:Adult; D044466:Asian People; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D010298:Parity; D011247:Pregnancy
chemical_list: D008055:Lipids