title: A rare case of peripheral vascular graft infection by Aspergillus fumigatus and review of the literature.
abstract: We present an unusual case of a 74-year-old woman who presented with a pseudoaneurysm at the site of a previous prosthetic femoro-popliteal bypass graft and underwent an urgent repair with pseudoaneurysm excision and extra-anatomic placement of an autologous venous graft. Microbiology examination revealed Aspergillus fumigatus infection of the graft, which is a very rare condition. Long-term antifungal medication has been administrated with positive outcome. Only a few cases have been reported in literature, mainly involving aortic grafts. Most patients are immunocompetent and with late presentation. Successful outcome can only be achieved with long-term antifungal treatment and extra-anatomic replacement of the graft.
authors.affiliation: General Surgical Department, Queen's Hospital, Romford , Essex , UK.
authors.forename: D
authors.initials: D
authors.lastname: Zosimas
authors.affiliation: General Surgical Department, Queen's Hospital, Romford , Essex , UK.
authors.forename: A
authors.initials: A
authors.lastname: Abukar
authors.affiliation: General Surgical Department, Queen's Hospital, Romford , Essex , UK.
authors.forename: A
authors.initials: A
authors.lastname: Srilekha
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000175:diagnosis / Q000601:surgery*; D000785:Aneurysm, Infected / Q000175:diagnosis / Q000601:surgery*; D001228:Aspergillosis / Q000175:diagnosis / Q000601:surgery*; D001232:Aspergillus fumigatus; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D005260:Female; D006083:Graft Occlusion, Vascular / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D011138:Polytetrafluoroethylene / Q000009:adverse effects; D016459:Prosthesis-Related Infections / Q000601:surgery*; D035583:Rare Diseases; D012008:Recurrence; D012086:Reoperation; D016896:Treatment Outcome
chemical_list: D011138:Polytetrafluoroethylene
keywords: Aspergillus fumigatus; Vascular graft