title: Synthesis of Spirocyclic Oxindole Dihydrothiophenes by DBU-Catalyzed [3 + 2] Annulation of Morita-Baylis-Hillman Carbonates with Isothiocyanates.
abstract: A highly regioselective DBU-catalyzed [3 + 2] annulation of Morita-Baylis-Hillman carbonates with isothiocyanates was developed. This method allows rapid and efficient synthesis of spirocyclic oxindole dihydrothiophene products in moderate to high yields with excellent regioselectivities under simple conditions. A plausible reaction mechanism is also proposed.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Zhao
authors.affiliation: School of Pharmaceutical Engineering & Life Science, Changzhou University , Changzhou 213164, P. R. China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Ji-Kang
authors.initials: JK
authors.lastname: Xie
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Xiu-Qin
authors.initials: XQ
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Xu