title: [Not Available].
abstract: OBJECTIVE
  To evaluate the efficacy and influential factors for 308 nm excimer laser in the treatment of stable vitiligo patients.
  
  
  METHODS
  A total of 207 stable vitiligo patients with 1 763 patches were treated with 308 nm excimer laser. Open-label study was carried out to investigate the efficacy and safety regarding the treatment with 308 nm excimer laser, and to compare the response under different conditions including gender, age, duration, lesion location, and hair color.
  
  
  RESULTS
  After treatment, 560 (31.8%) patches achieved 100% repigmentation, 650 (36.9%) lesions showed 75%-99% repigmentation, 189(10.7%) showed 50%-75% repigmentation, 231(13.1%) showed 25%-49% repigmentation, 108(6.1%) showed 1%-24% repigmentation, 25(1.4%) displayed no response. The rates of total excellent response (50%-100% repigmentation) in underage patients was 86.9%, much higher than that in adult patients (P<0.001). Total excellent response rates was 90.6% in disease duration <2 years, and 40.7% in disease duration ≥2 years. Lesions on the faciocervical region responded better than trunk and limbs, showing 95.4%, 70.3%, and 41.7% total excellent response, respectively. Patients with poliosis showed 54.9% in total excellent response rate, much lower than 84.5% in patients without poliosis(P<0.001). No significant response differences in gender were found.
  
  
  CONCLUSIONS
  308 nm excimer laser is effective and safe in treatment of vitiligo. Aging, disease duration, lesion location, and hair color in lesion may be the influential factors for 308 nm excimer laser in treatment of vitiligo patients.
authors.affiliation: Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Li
authors.initials: L
authors.lastname: Lei
authors.affiliation: Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Jinhua
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Qinghai
authors.initials: Q
authors.lastname: Zeng
authors.affiliation: Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Caiyun
authors.initials: C
authors.lastname: Xi
authors.affiliation: Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Aiyuan
authors.initials: A
authors.lastname: Guo
authors.affiliation: Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005121:Extremities / Q000473:pathology / Q000528:radiation effects; D005145:Face / Q000473:pathology / Q000528:radiation effects; D005260:Female; D006200:Hair Color; D006801:Humans; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D012880:Skin Pigmentation / Q000528:radiation effects; D060726:Torso / Q000473:pathology / Q000528:radiation effects; D016896:Treatment Outcome; D014820:Vitiligo / Q000628:therapy*