title: Role, timing and technique of radiotherapy in pediatric pleuropulmonary synovial sarcoma.
abstract: The management of pediatric thoracic synovial sarcoma remains a matter of debate in clinical oncology, especially as regard to the local control of the disease. Surgery remains the gold standard, while the role and timing of radiotherapy is still controversial. We report a 14-year-old male, who has not received proper treatment at the time of diagnosis and initial management. Intensity-modulated irradiation was performed only at relapse, as a salvage treatment and, at 10-month follow-up, the young patient was free from relapse, without significant acute and subacute toxicity. We discuss the role and timing of radiotherapy in thoracic synovial sarcoma, a disease in which the need to increase local control should be placed in the foreground.
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Corrado
authors.initials: C
authors.lastname: Spatola
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Tocco
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Milazzotto
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Pagana
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Ilenia
authors.initials: I
authors.lastname: Chillura
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Bevilacqua
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Carmelo
authors.initials: C
authors.lastname: Militello
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Salamone
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Raffaele
authors.affiliation: UOC Chirurgia Toracica, AOU Policlinico-VE di Catania, Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Migliore
authors.affiliation: UOC Radiodiagnostica e Radioterapia, AOU Policlinico-VE di Catania, 95125, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Privitera
mesh_terms: D000293:Adolescent; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D000072078:Positron Emission Tomography Computed Tomography; D011879:Radiotherapy Dosage; D050397:Radiotherapy, Intensity-Modulated / Q000009:adverse effects / Q000379:methods; D013584:Sarcoma, Synovial / Q000175:diagnosis / Q000532:radiotherapy*; D013899:Thoracic Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D013997:Time Factors; D016896:Treatment Outcome
keywords: radiotherapy; sarcoma; synovial sarcoma