title: Re-engineering the Hippocampus.
abstract: As adult-generated neurons integrate into hippocampal circuits, they compete with mature neurons for inputs from the entorhinal cortex. By reducing spines on mature granule cells, McAvoy et al. (2016) find that new neurons integrate more efficiently, and this facilitates learning.
authors.affiliation: Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Epp
authors.affiliation: Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Psychology, University of Toronto, Toronto, ON M5S 3G3, Canada; Department of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada; Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: paul.frankland@sickkids.ca.
authors.forename: Paul W
authors.initials: PW
authors.lastname: Frankland
mesh_terms: D018728:Entorhinal Cortex; D006624:Hippocampus; D007858:Learning; D009474:Neurons