title: Endomicroscopy and Molecular Tools to Evaluate Inflammatory Bowel Disease.
abstract: Endoscopy is an essential tool for effective care of patients with inflammatory bowel disease (IBD), including Crohn disease and ulcerative colitis. The newest endoscopic small-field imaging technologies with confocal endomicroscopy have allowed real-time imaging of gastrointestinal mucosal during ongoing endoscopic evaluation and in vivo histology. Thus, endomicroscopy has a potential to further enhance the endoscopic evaluation of IBD. Advances in molecular in vivo imaging in IBD may be used not only to better understand the pathophysiology of IBD but also to guide optimized therapy and thus to allow a personalized, new approach to the IBD management.
authors.affiliation: Division of Gastroenterology, University of Pennsylvania, 3400 Civic Center PCAM 7 South, Philadelphia, PA 19104, USA.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Buchner
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA. Electronic address: Wallace.michael@mayo.edu.
authors.forename: Michael B
authors.initials: MB
authors.lastname: Wallace
mesh_terms: D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000473:pathology*; D007413:Intestinal Mucosa / Q000473:pathology*; D018613:Microscopy, Confocal / Q000379:methods*
keywords: Colonoscopy; Confocal endomicroscopy; Crohn's disease; Dysplasia; Inflammatory assessment; Molecular imaging; Ulcerative colitis