title: A meta-analysis on uterine transplantation: Redefining the limits of reproductive surgery.
abstract: In September 2014, the first baby grown in a transplanted uterus was born, which represented an astonishing scientific progress that will mark the history of human reproduction. The recipient was a 32-year-old woman with Rokytanski syndrome who became pregnant after a successful embryo transfer and had an uneventful pregnancy, giving birth to a healthy newborn and marking the beginning of a new era. Patients who do not have a uterus or have a dysfunctional uterus now have the chance of dreaming with pregnancy and motherhood. Combining principles of solid organ transplantation and techniques of human reproduction, uterus transplantation is the first ephemeral transplant performed in order to promote reproductive potential of women and may be removed after successful pregnancy. Worldwide, 11 uterine transplantations were performed in patients. Of these, seven maintained their reproductive potential, with viable transplanted uteri and regular menstrual cycles.
authors.affiliation: BS - Medical Student, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
authors.forename: Ana Flávia Garcia
authors.initials: AF
authors.lastname: Silva
authors.affiliation: PhD - Department of Gynecology and Obstetrics, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
authors.forename: Luiz Fernando Pina
authors.initials: LF
authors.lastname: Carvalho
mesh_terms: D004624:Embryo Transfer / Q000379:methods; D005260:Female; D006801:Humans; D007044:Hysterectomy; D011247:Pregnancy; D011256:Pregnancy Outcome; D027724:Reproductive Techniques, Assisted / Q000639:trends*; D016896:Treatment Outcome; D014599:Uterus / Q000637:transplantation*