title: Decoding the Protein Destruction Code: A Panoramic View.
abstract: Proteasome degradation is essential, but the intrinsic features of a protein that signals its destruction remain incompletely understood. In this issue of Molecular Cell, Geffen et al. (2016) report an unbiased and proteome-wide method that provided insights into the protein destruction signals and pathways.
authors.affiliation: MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
authors.forename: Esther
authors.initials: E
authors.lastname: Pilla
authors.affiliation: MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address: aberto@mrc-lmb.cam.ac.uk.
authors.forename: Anne
authors.initials: A
authors.lastname: Bertolotti
mesh_terms: D046988:Proteasome Endopeptidase Complex; D020543:Proteome
chemical_list: D020543:Proteome; D046988:Proteasome Endopeptidase Complex