title: Diagnosis and surgical treatment of mediastinal solitary fibrous tumor.
abstract: OBJECTIVE
  The aim of this study was to investigate the clinical features as well as the diagnosis and treatment methods for mediastinal solitary fibrous tumor (MSFT).
  
  
  METHODS
  The clinical data of 13 patients treated for pathologically confirmed MSFT were retrospectively analyzed. The clinical symptoms were mainly cough, chest tightness, chest pain and chest discomfort. It was difficult to distinguish MSFT from other types of tumors simply via imaging results, hence, the confirmative diagnosis required pathological and immunohistochemistry analysis.
  
  
  RESULTS
  The tumors were completely resected for all patients. All patients were discharged after surgery and followed up for 2-85 months. One patient died of cerebral hemorrhage 2 months after the surgery, and the rest of the patients experienced no recurrence or metastasis during the follow-up period.
  
  
  CONCLUSIONS
  MSFT is a rare type of mediastinal tumor, and the diagnosis requires pathological and immunohistochemical analysis. Surgical treatment is preferred, and a complete resection can achieve a good prognosis; however, postoperative adjuvant radiotherapy might be necessary for cases with extensive external invasion.
authors.affiliation: Department of Cardiothoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.|School of Medicine, Shandong University, Jinan, Shandong, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Cardiothoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.|School of Medicine, Shandong University, Jinan, Shandong, China.
authors.forename: Xuegang
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Cardiothoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Cardiothoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Tang
authors.affiliation: Department of Cardiothoracic Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Shi
authors.affiliation: Department of Radiotherapy, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
authors.forename: Gengming
authors.initials: G
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D008875:Middle Aged; D012189:Retrospective Studies; D054364:Solitary Fibrous Tumors / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*
keywords: diagnosis; mediastinal tumor; solitary fibrous tumor; treatment