title: [Clinical and pathological features of breast cancer in a population of Mexico].
abstract: BACKGROUND
  Breast cancer is the most common among women in our country, and its treatment is based on prognostic factors to categorize patients into different risk groups. In this study, the clinical and pathological features that play a role as a prognostic factor in a representative population with breast cancer in México are described.
  
  
  METHODS
  A descriptive analysis of the clinical and pathological features of women diagnosed with breast cancer, in a period from June 2005 to May 2014; registered in a database and calculated by simple frequencies.
  
  
  RESULTS
  A total of 4,411 patients were included, the average age at diagnosis was 53 years, 19.7% were diagnosed by mammography screening program and 80.3% derived from any signs or symptoms. Regarding the stages at diagnosis, 6.8% were carcinoma in situ, 36% at early stages (I and IIA), 45% locally advanced (IIB to IIIC), 7.7% metastatic and 3.9% unclassifiable. A 79% were ductal histology, lobular 7.8% and the rest, other types. Of ductal carcinomas, 9.1% were grade I, 54.1% grade II, and 34.6% grade III. Regarding the biological subtypes, 65.7% were luminal, 10.9% luminal Her positive, 8.7% pure Her 2 positive and 14.6% triple negative.
  
  
  CONCLUSIONS
  In the present study, we described the clinical and pathologic features of a group of Mexican women with breast cancer that might reflect a national landscape, and represent the prognostic factors to determine groups of risk and treatment decisions.
authors.affiliation: Cirugía oncológica, Instituto de Enfermedades de la Mama, Fundación de Cáncer de Mama, A.C. (FUCAM), Ciudad de México, México. Electronic address: tonomaffuz@yahoo.com.
authors.forename: Antonio
authors.initials: A
authors.lastname: Maffuz-Aziz
authors.affiliation: Estadística, Instituto de Enfermedades de la Mama, Fundación de Cáncer de Mama, A.C. (FUCAM), Ciudad de México, México.
authors.forename: Sonia
authors.initials: S
authors.lastname: Labastida-Almendaro
authors.affiliation: Radiología, Instituto de Enfermedades de la Mama, Fundación de Cáncer de Mama, A.C. (FUCAM), Ciudad de México, México.
authors.forename: Aura
authors.initials: A
authors.lastname: Espejo-Fonseca
authors.affiliation: Cirugía oncológica, Instituto de Enfermedades de la Mama, Fundación de Cáncer de Mama, A.C. (FUCAM), Ciudad de México, México.
authors.forename: Sergio
authors.initials: S
authors.lastname: Rodríguez-Cuevas
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000453:epidemiology* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000453:epidemiology / Q000473:pathology; D018275:Carcinoma, Lobular / Q000453:epidemiology* / Q000473:pathology; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D004967:Estrogens; D005260:Female; D018734:Genes, erbB-2; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D009376:Neoplasms, Hormone-Dependent / Q000453:epidemiology / Q000473:pathology; D011374:Progesterone; D012189:Retrospective Studies; D064726:Triple Negative Breast Neoplasms / Q000453:epidemiology / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D004967:Estrogens; D011374:Progesterone
keywords: Biological subtypes; Breast cancer in Mexico; Características clínicas; Clinical features; Cáncer de mama en México; Subtipos biológicos