title: Bone mass and vitamin D levels in Parkinson's disease: is there any difference between genders?
abstract: [Purpose] The aim of this study was to determine the bone mineral density, vitamin D level, and frequencies of osteopenia and osteoporosis in patients with Parkinson's disease and to compare male and female patients with the controls separately. [Subjects and Methods] One hundred fifteen Parkinson's disease patients (47 males, 68 females; age range: 55-85 years) and 117 age- and gender-matched controls (47 males, 70 females) were enrolled in the study. Bone mineral density measured by dual-energy X-ray absorptiometry and serum D vitamin levels of each participant were recorded. [Results] The mean lumbar spine, femur neck, and total femur bone mineral density levels, T-scores, and vitamin D levels were found to be significantly lower in Parkinson's disease patients in both genders. Furthermore, osteoporosis rates were found be significantly higher only in female Parkinson's disease patients compared with female controls. [Conclusion] Data from the present study revealed that while osteoporosis was significantly higher only in female Parkinson's disease patients, all Parkinson's disease patients had lower bone mineral density scores and vitamin D levels compared with the controls regardless of gender, suggesting that clinicians should pay attention to the osteoporosis risk in Parkinson's disease and that adequate preventive measures should be taken in order to limit the future risk due to osteoporotic fractures.
authors.affiliation: Physical Medicine and Rehabilitation Clinic, Ministry of Health Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Turkey.
authors.forename: Erhan Arif
authors.initials: EA
authors.lastname: Ozturk
authors.affiliation: Physical Medicine and Rehabilitation Clinic, Ministry of Health Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Gundogdu
authors.affiliation: Department of Physical Medicine and Rehabilitation, Abant Izzet Baysal University Faculty of Medicine, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Tonuk
authors.affiliation: Neurology Clinic, Ministry of Health Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Turkey.
authors.forename: Bilge Gonenli
authors.initials: BG
authors.lastname: Kocer
authors.affiliation: Physical Medicine and Rehabilitation Clinic, Ministry of Health Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Tombak
authors.affiliation: Neurology Clinic, Ministry of Health Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Turkey.
authors.forename: Selcuk
authors.initials: S
authors.lastname: Comoglu
authors.affiliation: Physical Medicine and Rehabilitation Clinic, Ministry of Health Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Turkey.
authors.forename: Aytul
authors.initials: A
authors.lastname: Cakci
keywords: Bone mass; Gender; Parkinson’s disease