title: Comparison of serum anti-mullerian hormone among fertile and infertile normal and diminished ovarian reserve groups.
abstract: To compare anti-mullerian hormone among fertile and infertile groups of women in their reproductive age.
  
  
  
  This case-control study was conducted at the Dow University of Health Sciences in collaboration with Civil Hospital, Karachi, from October 2011 to October 2012, and comprised fertile non-pregnant and infertile women. Serum anti-mullerian hormone levels were measured in both the infertile and fertile groups. Blood samples to determine anti-mullerian hormone levels were obtained irrespective of their menstrual cycle days. Infertile cases were further divided into two subgroups according to serum anti-mullerian hormone levels, into normal ovarian reserve group and diminished ovarian reserve group. SPSS 18 was used for data analysis.
  
  
  
  Of the 100 participants, 48(48%) women were fertile controls and 52(52%) were infertile. Of the latter, there were 30(57.69%) in the normal ovarian reserve group and 22(42.31%) in the diminished ovarian reserve group. The mean age of the participants was 26±4.026 years (range: 25-35 years). The mean values for the control, normal ovarian reserve and diminished ovarian reserve groups were 1.9±0.16 ng/ml, 0.89±0.47 ng/ml and 2.0±0.6 ng/ml, respectively (p=0.001).
  
  
  
  Mean concentration of serum anti-mullerian hormone in infertile women with diminished ovarian reserve was significantly lower than that in normal ovarian reserve group and fertile control women.
authors.affiliation: Department of Physiology, Liaquat National Medical College, Karachi.
authors.forename: Naila
authors.initials: N
authors.lastname: Parveen
authors.affiliation: Department of Anatomy, Jinnah Sind Medical University, Karachi, Pakistan.
authors.forename: Dur-E-Shewar
authors.initials: DE
authors.lastname: Rehman
authors.affiliation: Department of Physiology, University Medical & Dental College, Faisalabad, Pakistan.
authors.forename: Shireen
authors.initials: S
authors.lastname: Jawed
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007247:Infertility, Female; D065851:Ovarian Reserve; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D054304:Anti-Mullerian Hormone
keywords: Fertile women, Anti-mullerianhormone, Infertility.