title: The BRAF Inhibitor Vemurafenib Enhances UV-Induced Skin Carcinogenesis in Beta HPV38 E6 and E7 Transgenic Mice.
authors.affiliation: Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
authors.forename: Daniele
authors.initials: D
authors.lastname: Viarisio
authors.affiliation: Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
authors.forename: Karin
authors.initials: K
authors.lastname: Müller-Decker
authors.affiliation: Department of Dermatology, University Hospital Heidelberg and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
authors.forename: Jessica C
authors.initials: JC
authors.lastname: Hassel
authors.affiliation: Department of Pharmacology, University Hospital of Garches, APHP and Versailles Saint-Quentin-en-Yvelines University, Garches, France.
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Alvarez
authors.affiliation: Department of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
authors.forename: Christa
authors.initials: C
authors.lastname: Flechtenmacher
authors.affiliation: Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Pawlita
authors.affiliation: Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
authors.forename: Lutz
authors.initials: L
authors.lastname: Gissmann
authors.affiliation: International Agency for Research on Cancer (IARC), World Health Organization, Lyon, France. Electronic address: tommasino@iarc.fr.
authors.forename: Massimo
authors.initials: M
authors.lastname: Tommasino
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D003043:Cocarcinogenesis / Q000187:drug effects* / Q000528:radiation effects; D004195:Disease Models, Animal; D006801:Humans; D007211:Indoles / Q000009:adverse effects*; D008545:Melanoma / Q000188:drug therapy*; D051379:Mice; D008822:Mice, Transgenic; D027383:Papillomaviridae / Q000472:pathogenicity; D050725:Papillomavirus E7 Proteins / Q000235:genetics; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors* / Q000235:genetics; D012878:Skin Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D013449:Sulfonamides / Q000009:adverse effects*; D014466:Ultraviolet Rays / Q000009:adverse effects*; D000077484:Vemurafenib
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D050725:Papillomavirus E7 Proteins; D013449:Sulfonamides; D000077484:Vemurafenib; C482120:Braf protein, mouse; D048493:Proto-Oncogene Proteins B-raf