title: A case of unilateral and spontaneously resolving posterior uveitis with overlapping features of Vogt-Koyanagi-Harada disease and Acute Posterior Multifocal Placoid Pigment Epitheliopathy.
abstract: BACKGROUND
  VKH disease is a chronic, bilateral, granulomatous panuveitis with potential involvement of neurological, auditory and integumentary systems. On the other hand, APMPPE is believed to be an immune-driven chorioretinal vascular disease characterized by multifocal, flat, grey-white placoid lesions at the level of the RPE. We describe a case with overlapping figures of both conditions.
  
  
  METHODS
  A 19-year-old female presented with unilateral blurry vision and was found to have clinical and IVFA findings consistent with APMPPE. Her OCT study demonstrated typical VKH findings with large areas of serous neurosensory retinal detachment and intra-retinal cystoid spaces with enclosed membranous structures. She was closely followed but was not treated with high dose corticosteroid. Spontaneous and complete resolution of her symptoms and clinical, IVFA and OCT findings were achieved by day 25.
  
  
  CONCLUSIONS
  This is the first reported case of spontaneously resolving, unilateral VKH disease in the absence of high dose corticosteroid treatment with overlapping features of APMPPE.
  
  
  CONCLUSIONS
  The imaging and clinical findings of both VKH disease and APMPPE raise the notion that VKH disease and APMPPE could be an overlapping spectrum of inflammatory processes, rather than distinct disease entities.
authors.affiliation: Ivey Eye Institute, Western University, London, ON Canada ; St Joseph's Hospital, 268 Grosvenor Street, London, ON N6A 4V2 Canada.
authors.forename: Bo
authors.identifier: 0000-0001-8672-6475
authors.initials: B
authors.lastname: Li
authors.affiliation: University of Ottawa Eye Institute, University of Ottawa, Ottawa, ON Canada.
authors.forename: Ricarda J
authors.initials: RJ
authors.lastname: Bentham
authors.affiliation: Ivey Eye Institute, Western University, London, ON Canada.
authors.forename: John R
authors.initials: JR
authors.lastname: Gonder
keywords: APMPPE; Acute Posterior Multifocal Placoid Pigment Epitheliopathy; IVFA; OCT; Uveitis; VKH; Vogt–Koyanagi–Harada; White dot syndrome