title: Aberration-Corrected Transmission Electron Microscopic Study of the Central Dark Line Defect in Human Tooth Enamel Crystals.
abstract: Angstrom resolution images of human tooth enamel (HTE) crystallites were obtained using aberration-corrected high-resolution transmission electron microscopy and atomic-resolution scanning transmission electron microscopy in the modes of bright field, annular dark field, and high-angle annular dark-field. Images show that the central dark line (CDL) defect observed around the center of the HTE crystals is a site for caries formation in the HTE and has a thickness of ~0.2 nm. Results also suggest that the CDL goes through one of the OH- planes.
authors.affiliation: 1Instituto de Física,UNAM. Circuito de la Investigación s/n,Ciudad Universitaria.04510 Coyoacan,México,D.F.,México.
authors.forename: José
authors.initials: J
authors.lastname: Reyes-Gasga
authors.affiliation: 2INSERM UMR_S 1121,Faculté de Chirurgie Dentaire,Université de Strasbourg,67085 Strasbourg,France.
authors.forename: Joseph
authors.initials: J
authors.lastname: Hémmerlé
authors.affiliation: 3UMET,Bâtiment C6,Université de Lille 1-Sciences et Technologies,59650 Villeneuve d'Ascq,France.
authors.forename: Etienne F
authors.initials: EF
authors.lastname: Brès
mesh_terms: D003731:Dental Caries / Q000473:pathology*; D003743:Dental Enamel / Q000473:pathology* / Q000648:ultrastructure*; D006801:Humans; D017348:Microscopy, Electron, Scanning Transmission; D046529:Microscopy, Electron, Transmission
keywords: 
                 C
                 
                    s
                 -corrected high-resolution transmission electron microscopy; atomic resolution high-angle annular dark-field scanning transmission electron microscopy; central dark line defect; human tooth enamel crystals; hydroxyapatite