title: Modulatory Effects of Dietary Amino Acids on Neurodegenerative Diseases.
abstract: Proteins are playing a vital role in maintaining the cellular integrity and function, as well as for brain cells. Protein intake and supplementation of individual amino acids can affect the brain functioning and mental health, and many of the neurotransmitters in the brain are made from amino acids. The amino acid supplementation has been found to reduce symptoms, as they are converted into neurotransmitters which in turn extenuate the mental disorders. The biosynthesis of amino acids in the brain is regulated by the concentration of amino acids in plasma. The brain diseases such as depression, bipolar disorder, schizophrenia, obsessive-compulsive disorder (OCD), and Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HD) are the most common mental disorders that are currently widespread in numerous countries. The intricate biochemical and molecular machinery contributing to the neurological disorders is still unknown, and in this chapter, we revealed the involvement of dietary amino acids on neurological diseases.
authors.affiliation: Department of Zoology, Nizam College, Hyderabad, India. senthilanal@yahoo.com.
authors.forename: Senthilkumar
authors.initials: S
authors.lastname: Rajagopal
authors.affiliation: Department of Zoology, Nizam College, Hyderabad, India.
authors.forename: Supraj Raja
authors.initials: SR
authors.lastname: Sangam
authors.affiliation: Department of Zoology, Nizam College, Hyderabad, India.
authors.forename: Shubham
authors.initials: S
authors.lastname: Singh
authors.affiliation: Department of Zoology, Nizam College, Hyderabad, India.
authors.forename: Venkateswara Rao
authors.initials: VR
authors.lastname: Joginapally
mesh_terms: D000596:Amino Acids / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D001921:Brain / Q000187:drug effects / Q000502:physiology*; D004032:Diet; D004044:Dietary Proteins / Q000378:metabolism; D019587:Dietary Supplements; D006801:Humans; D019636:Neurodegenerative Diseases / Q000628:therapy*
chemical_list: D000596:Amino Acids; D004044:Dietary Proteins
keywords: Alzheimer’s disease; Amino acids; Calcium; Huntington’s diseases; Ketogenic diet; Parkinson’s disease