title: Neuroprotection during aortic surgery.
abstract: Neurological injury is a major limitation of aortic surgery, whether it involves spinal cord injury following intervention to the thoracoabdominal aorta, or stroke following surgery on the arch and ascending aorta. Despite an extensive body of literature and various proposals, a completely effective strategy to prevent or treat neurological injury remains elusive. In this article, we summarise the evidence for established and emerging strategies, and review current concepts in pathophysiology and risk assessment as they relate to neurological injury.
authors.affiliation: Department of Anesthesia & Pain Management, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address: Helenl@adhb.govt.nz.
authors.forename: Helen
authors.initials: H
authors.lastname: Lindsay
authors.affiliation: Department of Anesthesia & Pain Management, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address: Coimbatore.Srinivas@uhn.ca.
authors.forename: Coimbatore
authors.initials: C
authors.lastname: Srinivas
authors.affiliation: Department of Anesthesia & Pain Management, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address: George.djaiani@uhn.on.ca.
authors.forename: George
authors.initials: G
authors.lastname: Djaiani
mesh_terms: D001011:Aorta / Q000601:surgery*; D013502:General Surgery / Q000592:standards; D006801:Humans; D000066829:Neuroprotection; D012307:Risk Factors; D013119:Spinal Cord Injuries / Q000517:prevention & control*
keywords: aortic surgery; neurologic injury; neuromonitoring; neuroprotection; risk factors; spinal cord injury; stroke; temporary neurological dysfunction