title: Data on PRRSV infection promoted the subtype of porcine dendritic cells from mDCs to pDCs in vivo.
abstract: The related study has confirmed that porcine reproductive and respiratory syndrome virus (PRRSV) infection may impair mature states of DCs can lead to suboptimal adaptive immune response ("The role of porcine reproductive and respiratory syndrome virus infection in immunephenotype and Th1/Th2 balance of dendritic cells" (Jinling Liu, We Shu, Liaxia Liu et al., 2016) [1]). In this data article,the porcine dendritic cells (DCs) isolated from porcine peripheral blood and spleen were collected after infection with PRRSV, then the characteristics of the subset differentiation of DCs were analyzed with FACS Calibur Cytometer and fluorescence microscope respectively. This data is an important foundation for further investigation into immune suppression by PRRSV infection, and that, it also provides new data for the development of potential antiviral therapies based on DCs and PRRS vaccines.
authors.affiliation: Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, P.R. China.
authors.forename: Jinling
authors.initials: J
authors.lastname: Liu
authors.affiliation: The Preventive Center of Animal Disease of LiaoNing Province, No.95, Renhe Road, Shenbei District, Shenyang 110164, P.R. China.
authors.forename: Shu
authors.initials: S
authors.lastname: Wei
authors.affiliation: Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, P.R. China.
authors.forename: Lixia
authors.initials: L
authors.lastname: Liu
authors.affiliation: Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, P.R. China.
authors.forename: Lihui
authors.initials: L
authors.lastname: Yu
authors.affiliation: The 705 hospital Shen Xiang, Shenyang 110016, P.R. China.
authors.forename: Chunyan
authors.initials: C
authors.lastname: Wang
authors.affiliation: Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, P.R. China.
authors.forename: Yujun
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Immunology, Basic School of Medicine, China Medical University, No. 92, North Second Road, Shenyang 110001, P.R. China.
authors.forename: Fengping
authors.initials: F
authors.lastname: Shan
authors.affiliation: Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, P.R. China.
authors.forename: Guoshun
authors.initials: G
authors.lastname: Shen
keywords: Dendritic cells; PRRSV; Subtype