title: T1-weighted MR imaging of glioma at 3T: a comparative study of 3D MPRAGE vs. conventional 2D spin-echo imaging.
abstract: OBJECTIVE
  This study aims to investigate difference between magnetization-prepared rapid gradient-echo imaging (MPRAGE) and spin-echo (SE) imaging for evaluating glioma on pre-contrast-enhanced (CE) and post-CE T1-weighted images at 3 T.
  
  
  METHODS
  We retrospectively assessed pre-CE and post-CE T1-weighted images for tumor contrast in 64 consecutive glioma patients.
  
  
  RESULTS
  In the nonenhancing tumors, the contrast was significantly clearer in MPRAGE than SE. In the enhancing tumors, post-CE contrast ratio was significantly higher in SE than MPRAGE, but when subtraction images are evaluated, the difference got smaller.
  
  
  CONCLUSIONS
  MPRAGE can be a good substitute of SE for T1-weighted imaging of glioma.
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: tdodo@kuhp.kyoto-u.ac.jp.
authors.forename: Toshiki
authors.initials: T
authors.lastname: Dodo
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: tomokada@kuhp.kyoto-u.ac.jp.
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Okada
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: yakira@kuhp.kyoto-u.ac.jp.
authors.forename: Akira
authors.initials: A
authors.lastname: Yamamoto
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: mitsuk@kuhp.kyoto-u.ac.jp.
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Kanagaki
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: yfushimi@kuhp.kyoto-u.ac.jp.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Fushimi
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: tokadat@kuhp.kyoto-u.ac.jp.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Okada
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: asakata@kuhp.kyoto-u.ac.jp.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Sakata
authors.affiliation: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: yarakawa@kuhp.kyoto-u.ac.jp.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Arakawa
authors.affiliation: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: miy@kuhp.kyoto-u.ac.jp.
authors.forename: Susumu
authors.initials: S
authors.lastname: Miyamoto
authors.affiliation: Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. Electronic address: ktogashi@kuhp.kyoto-u.ac.jp.
authors.forename: Kaori
authors.initials: K
authors.lastname: Togashi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
keywords: MPRAGE; MRI; contrast enhancement; glioma