title: Penetration of 630nm laser and 5-aminolevulinic acid in tissue with intralesional photodynamic therapy.
abstract: Photodynamic therapy is a common treatment in dermatology for several diseases, its main limitation is the penetration of topical photosensitizer and light in the tissue. However intralesional photodynamic therapy is a new technique where the photosensitizer and sometimes a 630nm laser beam are applied inside the lesión, so it allows achieve deeper penetration. It has been used to treat basal cell carcinoma, hidradenitis suppurativa or keloids.
authors.affiliation: Department of Dermatology, Complejo Asistencial Universitario de León, Spain, C/Altas de Nava s/n León, Spain, Spain; University of León, Spain. Electronic address: majesv88@gmail.com.
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Suárez-Valladares
authors.affiliation: Department of Dermatology, Complejo Asistencial Universitario de León, Spain, C/Altas de Nava s/n León, Spain, Spain.
authors.forename: Manuel Ángel
authors.initials: MÁ
authors.lastname: Rodriguez-Prieto
authors.affiliation: Department of Dermatology, Complejo Asistencial Universitario de León, Spain, C/Altas de Nava s/n León, Spain, Spain.
authors.forename: Ricard
authors.initials: R
authors.lastname: Serra-Llusà
mesh_terms: D000368:Aged; D021542:Amino Acids, Neutral / Q000008:administration & dosage*; D003131:Combined Modality Therapy / Q000295:instrumentation / Q000379:methods; D019317:Evidence-Based Medicine; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation* / Q000379:methods; D008297:Male; D010778:Photochemotherapy / Q000295:instrumentation* / Q000379:methods; D017319:Photosensitizing Agents / Q000008:administration & dosage; D012867:Skin / Q000473:pathology / Q000528:radiation effects*; D012878:Skin Neoplasms / Q000473:pathology* / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D021542:Amino Acids, Neutral; D017319:Photosensitizing Agents; C013809:5-aminovaleric acid