title: The effect of low-dose ketamine via patient-controlled analgesic pump on morphine consumption in the postoperative period in thoracotomies: a systematic review protocol.
abstract: The objective of this systematic review is to determine if adding low-dose ketamine to a morphine patient-controlled analgesic pump will have an impact on the total consumption of morphine during the first 72 hours postoperative in patients over the age of 15 undergoing surgery involving thoracotomy. In addition, secondary outcomes assessing the impact on pain, nausea and vomiting will be evaluated for any alteration with ketamine co-administration.
authors.affiliation: Texas Christian University Center for Evidence-based Practice and Research: a Collaborating Center of the Joanna Briggs Institute, Fort Worth, Texas, USA.
authors.forename: Saul
authors.initials: S
authors.lastname: Martinez
authors.forename: Sherrin
authors.initials: S
authors.lastname: Alexander
mesh_terms: D016058:Analgesia, Patient-Controlled; D000700:Analgesics / Q000008:administration & dosage*; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage*; D009020:Morphine / Q000008:administration & dosage*; D010149:Postoperative Pain / Q000188:drug therapy*; D000078202:Systematic Reviews as Topic; D013908:Thoracotomy
chemical_list: D000700:Analgesics; D007649:Ketamine; D009020:Morphine