title: Multidrug-Resistant Gram-Negative Bacilli: Infection Control Implications.
abstract: Antimicrobial resistance is a common iatrogenic complication of both modern life and medical care. Certain multidrug resistant and extensively drug resistant Gram-negative organisms pose the biggest challenges to health care today, predominantly owing to a lack of therapeutic options. Containing the spread of these organisms is challenging, and in reality, the application of multiple control measures during an evolving outbreak makes it difficult to measure the relative impact of each measure. This article reviews the usefulness of various infection control measures in containing the spread of multidrug-resistant Gram-negative bacilli.
authors.affiliation: Clinical Microbiology Laboratory, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel; Department of Medicine, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Amos
authors.initials: A
authors.lastname: Adler
authors.affiliation: Department of Infectious Diseases, Barwon Health, Victoria, Australia.
authors.forename: N Deborah
authors.initials: ND
authors.lastname: Friedman
authors.affiliation: Department of Medicine, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel; Division of Infectious Diseases, Assaf Harofeh Medical Center, Zerifin 70300, Israel. Electronic address: drormarchaim@gmail.com.
authors.forename: Dror
authors.initials: D
authors.lastname: Marchaim
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D003428:Cross Infection; D024901:Drug Resistance, Multiple, Bacterial; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000472:pathogenicity; D016905:Gram-Negative Bacterial Infections; D006801:Humans; D017053:Infection Control
chemical_list: D000900:Anti-Bacterial Agents
keywords: ESKAPE Pathogens; Gram-negative; Infection control; MDROs; Nosocomial infections