title: Titration of intravenous synthetic oxytocin post vaginal birth following induction or augmentation.
abstract: Evidence exists for titration of intravenous oxytocin during induction and augmentation, whereas no evidence was identified for titration of intravenous oxytocin following vaginal birth, where management excluded oxytocin for postpartum haemorrhage (PPH). This retrospective cohort study explored this issue through patient case notes and computerised perinatal data. Analysis included 335 women comparing induction (n = 226, 67%) to augmentation (n = 109, 33%). The two groups differed in terms of: parity; oxytocin dosage; length of time on intravenous oxytocin; and the length of first and second stage labour. They had similar rates of PPH and titration of intravenous oxytocin following birth was rarely recorded.
authors.affiliation: School of Nursing, Midwifery and Paramedicine, Curtin University, Perth, Western Australia, Australia; Department of Nursing and Midwifery Education and Research, King Edward Memorial Hospital, Perth, Western Australia, Australia. Electronic address: Lucy.lewis@curtin.edu.au.
authors.forename: Lucy
authors.initials: L
authors.lastname: Lewis
authors.affiliation: School of Nursing, Midwifery and Paramedicine, Curtin University, Perth, Western Australia, Australia; Department of Nursing and Midwifery Education and Research, King Edward Memorial Hospital, Perth, Western Australia, Australia.
authors.forename: Yvonne L
authors.initials: YL
authors.lastname: Hauck
authors.affiliation: Department of Nursing and Midwifery Education and Research, King Edward Memorial Hospital, Perth, Western Australia, Australia.
authors.forename: Alissa
authors.initials: A
authors.lastname: Pemberton
authors.affiliation: Department of Nursing and Midwifery Education and Research, King Edward Memorial Hospital, Perth, Western Australia, Australia.
authors.forename: Caroline
authors.initials: C
authors.lastname: Crichton
authors.affiliation: King Edward Memorial Hospital, Perth, Western Australia, Australia.
authors.forename: Marion
authors.initials: M
authors.lastname: Conwell
mesh_terms: D061605:Administration, Intravenous; D000293:Adolescent; D000328:Adult; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007751:Labor, Induced; D007743:Labor, Obstetric; D010121:Oxytocin / Q000008:administration & dosage*; D036801:Parturition; D018743:Perinatal Care; D006473:Postpartum Hemorrhage / Q000188:drug therapy / Q000453:epidemiology; D011247:Pregnancy; D012189:Retrospective Studies; D014621:Vagina; D055815:Young Adult
chemical_list: D010121:Oxytocin
keywords: Augmentation of labour; Induction of labour; Intravenous oxytocin; Postpartum haemorrhage; Titration