title: Alternate Calcification in Microcapillaries for the Fabrication of Hydroxyapatite Films without Light Exposure, Calcination, or Applied Voltage.
abstract: We discuss an alternate method for calcification in microcapillaries for fabricating calcium phosphate films using silicone molds and calcifying solutions. Calcium phosphate films with a line/space of 5-50 µm were fabricated by controlling the concentrations of calcium chloride and sodium phosphate solutions. Plate-type crystals of hydroxyapatite were grown when the calcium phosphate films were immersed in hydroxyapatite precursors. In the initial stage of hydroxyapatite crystal growth, the c-plane of the crystals was grown parallel to the substrates, and subsequently the growth followed with the c-plane growing perpendicular to the substrates. In narrow capillaries, dendritic structures were formed with a tendency to grow in a direction parallel to the direction of the microcapillaries. This technique is useful in the micropatterning of biocompatible ceramics with a minimized material consumption and a short fabrication time.
authors.affiliation: Department of Applied Chemistry and Biochemistry, Kumamoto University.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Watanabe
authors.forename: Munetoyo
authors.initials: M
authors.lastname: Iida
authors.forename: Mutsuyoshi
authors.initials: M
authors.lastname: Matsumoto
mesh_terms: D002122:Calcium Chloride / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis* / Q000737:chemistry; D003460:Crystallization; D017886:Durapatite / Q000138:chemical synthesis* / Q000737:chemistry; D008027:Light; D010710:Phosphates / Q000737:chemistry
chemical_list: D020099:Coated Materials, Biocompatible; D010710:Phosphates; D017886:Durapatite; D002122:Calcium Chloride; C018279:sodium phosphate