title: Detraining-induced alterations in adipokines and cardiometabolic risk factors after nonlinear periodized resistance and aerobic interval training in obese men.
abstract: This study compared the effects of nonlinear resistance training (NRT), aerobic interval training (AIT), and detraining on adipokines and cardiometabolic risk factors in middle-aged obese men. Thirty-three obese men were randomly allocated to NRT (n = 12), AIT (n = 10), and control (CON, n = 11) groups. Subjects in experimental groups performed exercise protocols 3 days per week for 12 weeks followed by a 4-week detraining period. The NRT involved 55 min of weight training with flexible periodization. The AIT consisted of running on a treadmill (4 × 4-min intervals at 90% of maximal heart rate, with each interval separated by 3 min at 65%). Peak oxygen consumption increased significantly after training compared with CON (P < 0.01), but it increased more in the AIT group than in the NRT group (P = 0.004). After detraining, peak oxygen consumption decreased significantly in both training groups (P < 0.001); however, the value in the AIT group was still higher than that in the CON group (P = 0.003). No significant changes were observed in serum levels of omentin-1 and interleukin (IL)-18 after training (P > 0.05), but omentin-1 decreased significantly in both training groups and IL-18 increased significantly in the NRT group after detraining (P < 0.05). High-density lipoprotein cholesterol (HDL-C) increased significantly after training in the AIT group compared with the CON group (P < 0.05) and returned to the pre-training level after detraining. Conversely, apelin-13 increased significantly in response to training, compared with baseline (P < 0.05), and remained unchanged after detraining. Both training regimens had similar effects on most markers; however, AIT seems to have stronger anti-coronary disease effects (as indicated by HDL-C and peak oxygen consumption) than NRT.
authors.affiliation: a Department of Exercise Physiology, Islamic Azad University, Ilam Branch, Ilam, Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Nikseresht
authors.affiliation: b Department of Pathobiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Hafezi Ahmadi
authors.affiliation: c Cellular & Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Hedayati
mesh_terms: D050154:Adiposity; D000328:Adult; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D008076:Cholesterol, HDL / Q000097:blood; D016207:Cytokines / Q000097:blood*; D058851:GPI-Linked Proteins / Q000097:blood; D000072696:High-Intensity Interval Training; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood; D020382:Interleukin-18 / Q000097:blood*; D007492:Iran / Q000453:epidemiology; D037102:Lectins / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D010101:Oxygen Consumption; D055070:Resistance Training; D012307:Risk Factors; D055105:Waist Circumference
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; D016207:Cytokines; D058851:GPI-Linked Proteins; C000589760:IL18 protein, human; C432397:ITLN1 protein, human; D036341:Intercellular Signaling Peptides and Proteins; D020382:Interleukin-18; D037102:Lectins; C495199:apelin-13 peptide
keywords: entraînement à la force; inflammation; lipid metabolism; métabolisme lipidique; obesity; obésité; strength training