title: Low-intensity laser (660 nm) on sternotomy healing in patients who underwent coronary artery bypass graft: a randomized, double-blind study.
abstract: The aim of this study was to analyze the healing effects of low-level laser therapy (LLLT) on the longitudinal sternotomy incisions of patients who underwent coronary artery bypass graft (CABG). The volunteers were randomized into three groups of equal size (n = 30): control, placebo, and laser (λ = 660 nm and spatial average energy fluency [SAEF] = 1.06 J/cm2). The patients in the laser group underwent irradiation on postoperative days 2, 4, 6, and 8, and their sternotomy incisions were photographed immediately after the surgery and 8 days later for analysis. Three researchers who were blinded to the patient treatment groups analyzed the incision photographs to assess hyperemia and wound closure on the day of hospital discharge (eighth postoperative day). The sternotomy incisions in the LLLT group demonstrated less hyperemia, incisional bleeding, and dehiscence (p ≤ 0.005).
authors.affiliation: Lasertherapy and Photobiology Center, Research and Development Institute, IP&D, Universidade do Vale do Paraíba, UNIVAP, São Paulo, Brazil. gilderlene@yahoo.com.br.|Uninovafapi College, Teresina, Piauí, Brazil. gilderlene@yahoo.com.br.|, Vitorino Orthigues Fernandes Street, 6123, Teresina, Piaui, 64073-505, Brazil. gilderlene@yahoo.com.br.
authors.forename: Gilderlene Alves
authors.initials: GA
authors.lastname: Fernandes
authors.affiliation: Lasertherapy and Photobiology Center, Research and Development Institute, IP&D, Universidade do Vale do Paraíba, UNIVAP, São Paulo, Brazil.|University of Piauí State (UESPI), Teresina, Piauí, Brazil.
authors.forename: Andréa Conceição Gomes
authors.initials: AC
authors.lastname: Lima
authors.affiliation: Lasertherapy and Photobiology Center, Research and Development Institute, IP&D, Universidade do Vale do Paraíba, UNIVAP, São Paulo, Brazil.|Uninovafapi College, Teresina, Piauí, Brazil.
authors.forename: Isabel Clarisse Albuquerque
authors.initials: IC
authors.lastname: Gonzaga
authors.affiliation: Cardiac Surgery Department, Santa Maria Hospital, Teresina, Piauí, Brazil.
authors.forename: Raimundo
authors.initials: R
authors.lastname: de Barros Araújo
authors.affiliation: Uninovafapi College and University of Piauí State (UESPI), Teresina, Piauí, Brazil.
authors.forename: Rauirys Alencar
authors.initials: RA
authors.lastname: de Oliveira
authors.affiliation: Lasertherapy and Photobiology Center, Research and Development Institute, IP&D, Universidade do Vale do Paraíba, UNIVAP, São Paulo, Brazil.
authors.forename: Renata Amadei
authors.initials: RA
authors.lastname: Nicolau
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass / Q000379:methods*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D056346:Sternotomy / Q000379:methods*; D014945:Wound Healing / Q000528:radiation effects*
keywords: Coronary artery bypass graft; Incision healing; Low-intensity laser therapy; Sternotomy