title: Association of metabolic factors with dengue viral infection on admission triage which predict its clinical course during Lahore dengue epidemic.
abstract: The study was done to identify metabolic factors which were associated with an increased risk of dengue haemorrhagic fever in clinically diagnosed patients of dengue viral infection.
  
  
  
  563 patients with dengue viral infection that presented to 3 tertiary care hospitals of Lahore were included in this study, out of which approximately half of the patients were diagnosed as dengue haemorrhagic fever.
  
  
  
  A total of 563 patients with 263(46.7%) dengue fever and 300(53.3%) dengue haemorrhagic fever patients were studied. The mean age of patients was 48.48 ± 20.07 years. In patients younger than 60 (n=355), 171 patients had DF and 184 had DHF, while 116 patients above 60 years had DHF and 92 had DF (n=208). The presence of metabolic risk factors such as diabetes (OR = 2.146), hypertension (OR =1.65), diabetes and hypertension (OR =3.56), abnormal liver function tests (OR = 2.27), abnormal renal function tests (OR = 2.282) all increased the risk of DHF relative to DF.
  
  
  
  The study showed that metabolic factors especially diabetes with and without hypertension are important risk factors for the development of DHF.
authors.affiliation: Department of Endocrinology and Metabolism, Services Hospital, Lahore.
authors.forename: Amena Moazzam
authors.initials: AM
authors.lastname: Baig Mirza
authors.affiliation: House Officer, Lahore.
authors.forename: Madiha
authors.initials: M
authors.lastname: Fida
authors.affiliation: Medical Officer, Lahore.
authors.forename: Ghulam
authors.initials: G
authors.lastname: Murtaza
authors.affiliation: Medical Officer, Lahore.
authors.forename: Rizwan
authors.initials: R
authors.lastname: Niazi
authors.affiliation: Department of Biostatistics, Ghulab Devi Hospital, Lahore.
authors.forename: Asif
authors.initials: A
authors.lastname: Hanif
authors.affiliation: Department of Endocrinology and Metabolism, Services Hospital, Lahore.
authors.forename: Khadija
authors.initials: K
authors.lastname: Irfan
authors.affiliation: Department of Endocrinology and Metabolism, Services Hospital, Lahore.
authors.forename: Faisal
authors.initials: F
authors.lastname: Masud
mesh_terms: D000328:Adult; D000368:Aged; D003715:Dengue / Q000175:diagnosis* / Q000453:epidemiology / Q000378:metabolism; D003716:Dengue Virus; D048909:Diabetes Complications; D058872:Epidemics; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008875:Middle Aged; D012307:Risk Factors; D019595:Severe Dengue; D014218:Triage
keywords: DHF: Dengue hemorrhagic Fever, DF: Dengue Fever, LFT: Liver Function tests, RFT: Renal Function Test.