title: Renal dysfunction and transcatheter aortic valve implantation outcomes.
abstract: Transcatheter aortic valve implantation (TAVI) underwent progressive improvements until it became the default therapy for inoperable patients, and a recommended therapy in high-risk operable patients with symptomatic severe aortic stenosis. Recent evidence will further support TAVI as treatment for a growing number of patients. Areas covered: This review will discuss on the current knowledge about the role of both pre-procedural chronic kidney disease (CKD) and post-procedural acute kidney injury (AKI) in adult patients with severe aortic stenosis undergoing TAVI. Expert commentary: Pre-procedural CKD is one of the most frequent comorbidities of TAVI patients and has been found to significantly worsen patients' prognosis at short and long-term follow-up. Similarly, post-procedural AKI is a frequent and relevant complication associated with increased mortality. The risk stratification of the patient, the prevention of complications and the appropriate post-procedural management are the main focus of the future research aimed at further improving clinical outcomes of TAVI patients.
authors.affiliation: a Division of Cardiology, Ferrarotto Hospital , University of Catania , Catania , Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Barbanti
authors.affiliation: b Division of Cardiology - Department of Advanced Biomedical Sciences , Federico II University , Naples , Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Gargiulo
authors.affiliation: a Division of Cardiology, Ferrarotto Hospital , University of Catania , Catania , Italy.|c Excellence Through Newest Advances (ETNA) Foundation , Catania , Italy.
authors.forename: Corrado
authors.initials: C
authors.lastname: Tamburino
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D001024:Aortic Valve Stenosis / Q000601:surgery*; D006801:Humans; D011379:Prognosis; D051436:Renal Insufficiency, Chronic / Q000150:complications; D012307:Risk Factors; D065467:Transcatheter Aortic Valve Replacement / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome
keywords: TAVI; acute kidney injury; chronic kidney disease; mortality; renal dysfunction