title: Bringing the Hepatitis C Virus to Life.
abstract: Charles Rice and Ralf Bartenschlager, together with Michael Sofia, are the recipients of the 2016 Lasker∼DeBakey Clinical Award. Their discoveries led to the development of a system to study the replication of hepatitis C virus, which causes a chronic and lethal disease in humans, and the use of this system to develop drugs that cure the illness. Charlie and Ralf joined Cell editor João Monteiro in a conversation about their achievements, current challenges, and the future of HCV research.
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000627:therapeutic use; D001363:Awards and Prizes; D035843:Biomedical Research; D055808:Drug Discovery; D016174:Hepacivirus / Q000502:physiology*; D006526:Hepatitis C / Q000188:drug therapy / Q000821:virology*; D006801:Humans; D014779:Virus Replication
chemical_list: D000998:Antiviral Agents