title: Ultraviolet B radiation therapy for psoriasis: Pursuing the optimal regime.
abstract: Psoriasis is a chronic and common disease mediated by resident memory T cells that negatively affects a broad range of people worldwide. One of the oldest and most commonly used treatments is phototherapy. We reviewed the existing literature on the four main ultraviolet B (UVB) modalities of phototherapy in the management of psoriasis: heliotherapy, broadband UVB, narrowband UVB, and excimer laser and lamp. Despite the many studies done on these therapies, there is significant variation in their prescription and use. Phototherapy remains one of the most effective and safest treatments for psoriasis. We provide an updated comprehensive overview of UVB phototherapy for psoriasis to help physicians optimize their choice of modality and dosing regimen to ensure optimal outcomes for psoriasis patients. © 2016 Elsevier Inc. All rights reserved.
authors.affiliation: Newton Wellesley Hospital Department of Dermatology, Newton, MA; Academic Medical Center, Department of Dermatology, University of Amsterdam, Amsterdam, 1105 AZ, Netherlands. Electronic address: tiagoreismatos@gmail.com.
authors.forename: Tiago R
authors.initials: TR
authors.lastname: Matos
authors.affiliation: Consultant Dermatologist for Phototherapy and Photobiology Unit, Dermatology Centre, Salford Royal Hospital, Manchester, M6 8 HD, UK.
authors.forename: Tsui C
authors.initials: TC
authors.lastname: Ling
authors.affiliation: Newton Wellesley Hospital Department of Dermatology, Newton, MA.
authors.forename: Vaneeta
authors.initials: V
authors.lastname: Sheth
mesh_terms: D000075202:Contraindications; D006370:Heliotherapy; D006801:Humans; D054018:Lasers, Excimer / Q000627:therapeutic use*; D018579:Patient Selection; D011565:Psoriasis / Q000532:radiotherapy*; D014467:Ultraviolet Therapy / Q000009:adverse effects / Q000379:methods*