title: Elective Surgery of Umbilical Hernia as a First Clinical Manifestation of a Gastrointestinal Stromal Tumor (Gist) - Case Report.
abstract: Gastrointestinal stromal tumor is a rare pathology. GISTs account for 0.3-1% of all tumors of the gastrointestinal tract. At the same time, this type of cancer is the most common, malignant, non-epithelial tumor of the gastrointestinal tube. Over 90% of GISTs are found in the stomach and small intestine. This cancer usually develops without characteristic clinical symptoms and is diagnosed incidentally. This clinical situation, in which the first symptom of a GIST-pattern tumor includes a fully-symptomatic, non-complicated umbilical hernia, is an unprecedented anomaly. This work presents a case report of a 77-year old female patient undergoing elective surgery, in which the contents of the hernial sac included a stromal tumor. Disseminated, multi-focal progression of the disease was found intraoperatively. Postoperative histopathology and immunohistochemistry revealed a gastrointestinal stromal tumor GIST of the spindle cell type, showing a CD-117, CD-34, SMA expression with possible starting point in the small intestine.
authors.forename: Bartosz
authors.initials: B
authors.lastname: Cybułka
authors.forename: Maciej
authors.initials: M
authors.lastname: Golański
authors.forename: Jacek
authors.initials: J
authors.lastname: Rapeła
authors.forename: Andrzej
authors.initials: A
authors.lastname: Wach
mesh_terms: D000368:Aged; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000150:complications*; D006554:Hernia, Umbilical / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D011044:Poland; D016896:Treatment Outcome