title: [Organ replacement therapy - extracorporeal liver assist devices].
abstract: Liver failure is a disease with a high mortality rate. Often liver transplantation is the sole therapeutic option. On the one hand, liver support systems probably support the liver to allow regeneration, on the other hand they are an option to bridge for transplantation. This article gives an overview on the clinically used liver assist devices (molecular adsorbent recirculating system [MARS], Prometheus system, single-pass albumin dialysis [SPAD], plasmapheresis) and discusses the applications in liver failure.
authors.affiliation: Klinik für Anästhesiologie, Universitätssklinikum Regensburg.
authors.forename: Barbara
authors.initials: B
authors.lastname: Sinner
authors.affiliation: Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Regensburg.
authors.forename: Gabriele I
authors.initials: GI
authors.lastname: Kirchner
mesh_terms: D001781:Blood Component Removal; D003131:Combined Modality Therapy / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D019317:Evidence-Based Medicine; D005112:Extracorporeal Circulation / Q000295:instrumentation* / Q000379:methods; D005440:Fluid Therapy / Q000295:instrumentation / Q000379:methods; D006801:Humans; D017093:Liver Failure / Q000175:diagnosis / Q000628:therapy*; D016031:Liver Transplantation / Q000295:instrumentation / Q000379:methods; D019164:Liver, Artificial; D010530:Peritoneal Dialysis / Q000295:instrumentation / Q000379:methods*; D010956:Plasmapheresis / Q000295:instrumentation / Q000379:methods*; D006435:Renal Dialysis / Q000295:instrumentation* / Q000379:methods; D012709:Serum Albumin / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D012709:Serum Albumin