title: Combined assessment using optical colonoscopy and computed tomographic colonography improves the determination of tumor location and invasion depth.
abstract: BACKGROUND
  An accurate assessment of the depth of tumor invasion in patients with colon cancer is an important part of the preoperative evaluation. Whether computed tomographic colonography (CTC) or optical colonoscopy (OC) is better to accurately determine tumor location and invasion depth has not been definitively determined. The aim of this study was to determine the diagnostic accuracy of tumor localization and tumor invasion depth of colon cancer by preoperative OC alone or combined with CTC.
  
  
  METHODS
  Study participants include 143 patients who underwent both preoperative CTC using automated CO2insufflation and OC from July 2012 to August 2013.
  
  
  RESULTS
  The accuracy of tumor localization was significantly better with CTC than with OC (OC, 90%; CTC, 98%; P < 0.05). No tumor in the descending colon was localized accurately via OC alone. The accuracy of tumor invasion depth was better with CTC plus OC than with OC alone (OC, 55%; CTC, 73%; P < 0.05).
  
  
  CONCLUSIONS
  OC combined with CTC provides a more accurate preoperative determination of tumor localization and invasion depth than OC alone.
authors.affiliation: Department of Radiology, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Kanazawa
authors.affiliation: Department of Coloproctology, Aizu Medical Center, Aizuwakamatsu, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Utano
authors.affiliation: Department of Radiology, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Shigeyoshi
authors.initials: S
authors.lastname: Kijima
authors.affiliation: Department of Radiology, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Sasaki
authors.affiliation: Department of Surgery, Jichi Medical University, Shimotsuke, Japan.|Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Miyakura
authors.affiliation: Department of Surgery, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Hisanaga
authors.initials: H
authors.lastname: Horie
authors.affiliation: Department of Surgery, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Alan Kawarai
authors.initials: AK
authors.lastname: Lefor
authors.affiliation: Department of Radiology, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Hideharu
authors.initials: H
authors.lastname: Sugimoto
mesh_terms: D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D023881:Colonography, Computed Tomographic; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011300:Preoperative Care; D012189:Retrospective Studies
keywords: Colonic neoplasms; colonography; colonoscopy