title: Frequent alternative lengthening of telomeres and ATRX loss in adult NF1-associated diffuse and high-grade astrocytomas.
authors.affiliation: Department of Pathology, Johns Hopkins University, Sheikh Zayed Tower, Room M2101, 1800 Orleans Street, Baltimore, MD, 21231, USA. frodrig4@jhmi.edu.|Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA. frodrig4@jhmi.edu.
authors.forename: Fausto J
authors.initials: FJ
authors.lastname: Rodriguez
authors.affiliation: Department of Pathology, Johns Hopkins University, Sheikh Zayed Tower, Room M2101, 1800 Orleans Street, Baltimore, MD, 21231, USA.
authors.forename: M Adelita
authors.initials: MA
authors.lastname: Vizcaino
authors.affiliation: Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.|Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Jaishri
authors.initials: J
authors.lastname: Blakeley
authors.affiliation: Department of Pathology, Johns Hopkins University, Sheikh Zayed Tower, Room M2101, 1800 Orleans Street, Baltimore, MD, 21231, USA.|Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Heaphy
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics; D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000235:genetics* / Q000378:metabolism* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D056970:Co-Repressor Proteins; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007521:Isocitrate Dehydrogenase / Q000235:genetics; D008297:Male; D008875:Middle Aged; D018832:Molecular Chaperones; D018302:Neoplasms, Neuroepithelial / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D009456:Neurofibromatosis 1 / Q000150:complications / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics; D016615:Telomere / Q000473:pathology*; D059505:Telomere Homeostasis / Q000235:genetics*; D000075924:X-linked Nuclear Protein / Q000235:genetics / Q000378:metabolism*; D055815:Young Adult
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D056970:Co-Repressor Proteins; C106985:DAXX protein, human; D018832:Molecular Chaperones; D009687:Nuclear Proteins; D007521:Isocitrate Dehydrogenase; C092332:ATRX protein, human; D000075924:X-linked Nuclear Protein