title: Polyglucosan Bodies in the Prostatic Stromal Smooth Muscles of Aged Dogs.
abstract: Polyglucosan bodies (PGB) in the prostate of aged dogs without neurological signs were examined by light microscopy, histochemistry and immunohistochemistry. Prostatic PGB were round or oval and slightly basophilic. Most of the bodies were situated within the stromal smooth muscle cells. PGB were intensely positive for PAS, Best's carmine, Lugol's iodine and Grocott's methenamine silver method. Moreover, canine prostatic PGB were immunoreactive for monoclonal antibodies raised against human polyglucosan. The frequency of PGB in the smooth muscle cells was significantly correlated with the age of dogs. The occurrence of PGB in the canine prostate might be a non-specific finding related to ageing.
authors.affiliation: Department of Applied Science, School of Veterinary Nursing and Technology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Kamiya
authors.affiliation: Department of Applied Science, School of Veterinary Nursing and Technology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan. yoshimura-h@nvlu.ac.jp.
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yoshimura
authors.affiliation: Department of Applied Science, School of Veterinary Nursing and Technology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan.
authors.forename: Keina
authors.initials: K
authors.lastname: Okada
authors.affiliation: Department of Applied Science, School of Veterinary Nursing and Technology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan.
authors.forename: Ayaka
authors.initials: A
authors.lastname: Yoshida
authors.affiliation: Department of Applied Science, School of Veterinary Nursing and Technology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Fukuda
authors.affiliation: Department of Applied Science, School of Veterinary Nursing and Technology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan.
authors.forename: Masami
authors.initials: M
authors.lastname: Yamamoto
authors.affiliation: Department of Veterinary Anatomy, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Soeta
authors.affiliation: Departments of Veterinary Pathology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Kyonan-cho, Musashino, Tokyo, Japan.
authors.forename: Kimimasa
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D000375:Aging / Q000473:pathology*; D000818:Animals; D004285:Dogs; D005936:Glucans / Q000378:metabolism*; D007150:Immunohistochemistry; D002479:Inclusion Bodies / Q000378:metabolism*; D008297:Male; D009130:Muscle, Smooth / Q000473:pathology*; D011467:Prostate / Q000473:pathology*
chemical_list: D005936:Glucans; C083094:polyglucosan