title: [Fatal acute interstitial lung disease associated with docetaxel administration: about a case and review of the literature].
abstract: Docetaxel is a chemotherapeutic agent belonging to the taxane family. This drug is widely used to treat cancers. Interstitial lung disease is a rare but serious toxicity due to the high mortality risk. We report a case of a patient with breast cancer who had fatal acute interstitial lung disease after auxiliary chemotherapy with docetaxel. The clinician should be aware of this risk and should consider it in differential diagnosis in patients with respiratory symptoms treated with docetaxel.
authors.affiliation: Service d'Oncologie Médicale, Centre Hospitalier Mohammed VI, Oujda, Maroc.
authors.forename: Sami Aziz
authors.initials: SA
authors.lastname: Brahmi
authors.affiliation: Service d'Oncologie Médicale, Centre Hospitalier Mohammed VI, Oujda, Maroc.
authors.forename: Seddik
authors.initials: S
authors.lastname: Youssef
authors.affiliation: Service d'Oncologie Médicale, Centre Hospitalier, Hassan II, Fès, Maroc.
authors.forename: Fatima Zahra
authors.initials: FZ
authors.lastname: Ziani
authors.affiliation: Service d'Oncologie Médicale, Centre Hospitalier Mohammed VI, Oujda, Maroc.
authors.forename: Said
authors.initials: S
authors.lastname: Afqir
mesh_terms: D000208:Acute Disease; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D003937:Diagnosis, Differential; D000077143:Docetaxel; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000175:diagnosis; D043823:Taxoids / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D000077143:Docetaxel
keywords: Cancer; docetaxel; interstitial lung disease