title: Second dose of PGE2vaginal insert versus Foley transcervical balloon for induction of labor after failure of cervical ripening with PGE2vaginal insert.
abstract: OBJECTIVE
  To determine the success rate of induction of labor (IOL) using Foley transcervical balloon (FTB) versus prostaglandin E2(PGE2) vaginal insert, following failure of cervical ripening with PGE2vaginal insert.
  
  
  METHODS
  A retrospective cohort study of all pregnant women admitted for IOL with either FTB or PGE2vaginal insert. Either second dose of PGE2vaginal insert or FTB was used as a second line treatment after failure (not giving birth in 24 h from insertion) of first PGE2vaginal insert.
  
  
  RESULTS
  During the study period, 1162 women were admitted for IOL. Failure was reported in 322/852 (37.8%) in the FTB versus 162/310 (52.2%) in the PGE2group (p < 0.001). Among 162 patients treated with PGE2as first line who did not deliver after 24 h, 14 had spontaneous rupture of membranes, 15 underwent stripping and 42 were in still in active labor. The remainder were allocated to either second trial of PGE2treatment (n = 58) or FTB (n = 33) with failure rate higher in the PGE2group, not statistically significant (p = 0.23).
  
  
  CONCLUSIONS
  IOL with FTB was not superior to PGE2vaginal insert for IOL following failure of cervical ripening with PGE2vaginal insert.
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.
authors.forename: Aya
authors.initials: A
authors.lastname: Mohr-Sasson
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.|b Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
authors.forename: Eyal
authors.initials: E
authors.lastname: Schiff
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.
authors.forename: Ofra
authors.initials: O
authors.lastname: Sindel
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.
authors.forename: Ramy Rahamim
authors.initials: RR
authors.lastname: Suday
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.|b Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
authors.forename: Anat
authors.initials: A
authors.lastname: Kalter-Farber
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.|b Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
authors.forename: Roy
authors.initials: R
authors.lastname: Mashiach
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.|b Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
authors.forename: Yoav
authors.initials: Y
authors.lastname: Yinon
authors.affiliation: b Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
authors.forename: Moti
authors.initials: M
authors.lastname: Dulitzki
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.|b Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
authors.forename: Eyal
authors.initials: E
authors.lastname: Sivan
authors.affiliation: a Department of Obstetrics and Gynecology , Sheba Medical Center , Tel-Hashomer , Israel and.|b Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.
authors.forename: Shali
authors.initials: S
authors.lastname: Mazaki-Tovi
mesh_terms: D000282:Administration, Intravaginal; D000328:Adult; D002404:Catheterization; D020070:Cervical Ripening / Q000187:drug effects; D002584:Cervix Uteri / Q000187:drug effects; D015232:Dinoprostone / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000295:instrumentation / Q000379:methods*; D010120:Oxytocics / Q000008:administration & dosage*; D011247:Pregnancy; D012044:Regression Analysis; D012189:Retrospective Studies
chemical_list: D010120:Oxytocics; D015232:Dinoprostone
keywords: Foley transcervical balloon; Induction of labor; cervical ripening; dinoprostone; prostaglandin E2 vaginal insert