title: Synthesis of Enantioenriched Pyrrolidines via Gold-Catalyzed Tandem Cycloisomerization/Hydrogenation of Chiral Homopropargyl Sulfonamides.
abstract: A novel gold-catalyzed tandem cycloisomerization/hydrogenation of chiral homopropargyl sulfonamides has been developed. Various enantioenriched pyrrolidines can be obtained in excellent yields and excellent enantioselectivities by combination of chiral tert-butylsulfinimine chemistry with gold catalysis. Importantly, this represents the first example of a pyrrolidine synthesis from homopropargyl sulfonamide.
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, China.
authors.forename: Yong-Fei
authors.initials: YF
authors.lastname: Yu
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Shu
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, China.
authors.forename: Tong-De
authors.initials: TD
authors.lastname: Tan
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, China.
authors.forename: Long
authors.initials: L
authors.lastname: Li
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, China.
authors.forename: Shahid
authors.initials: S
authors.lastname: Rafique
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University , Xiamen 361005, China.|State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences , Shanghai 200032, China.
authors.forename: Long-Wu
authors.initials: LW
authors.lastname: Ye