title: Comparative evaluation of co-enzyme Q10 and Melaleuca alternifolia as antioxidant gels in treatment of chronic periodontitis: A clinical study.
abstract: BACKGROUND
  Conventional nonsurgical periodontal therapy has been proven to be an effective treatment for patients with chronic periodontitis. Coenzyme Q10 and tea tree oil (TTO) are known to have potential therapeutic benefits in chronic periodontitis.
  
  
  OBJECTIVE
  The aim of the study is to compare the efficacy of Coenzyme Q10 (Perio Q(®)) and tea tree oil (Melaleuca alternifolia) gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis.
  
  
  METHODS
  Patients were divided equally into three groups: Group I (Control group): those receiving placebo gel + SRP, Group II (Test group I): those receiving Perio Q(TM) gel + SRP, and Group III (Test group II): those receiving tea tree oil gel + SRP. A total of 15 patients with 45 sites were enrolled in the study. Clinical parameters evaluated were plaque index (PI), gingival bleeding index (GI), probing pocket depth (PPD), and clinical attachment level (CAL).
  
  
  METHODS
  Paired t-test was applied using SPSS software.
  
  
  RESULTS
  Mean PPD reduction for Group I, Group II, and Group III was 0.50 ± 0.2, 2.95 ± 0.20, and 2.09 ± 0.15, respectively. Mean CAL reduction for Group I, Group II, and Group III was 0.45 ± 0.22, 2.33 ± 0.04, and 2.28 ± 0.09, respectively. Changes in mean PI scores for Group I, Group II, and Group III were 0.67 ± 017, 1.00 ± 0.11, and 1.08 ± 0.05 and GBI scores were 0.92 ± 0.29, 1.08 ± 0.13, and 0.88 ± 0.28, respectively.
  
  
  CONCLUSIONS
  Coenzyme Q10 and tea tree oil gel proved to be effective in the treatment of chronic periodontitis.
authors.affiliation: Department of Periodontology, MGV's KBH Dental College and Hospital, Nashik, Maharashtra, India.
authors.forename: Chetan Purushottam
authors.initials: CP
authors.lastname: Raut
authors.affiliation: Department of Periodontology, MGV's KBH Dental College and Hospital, Nashik, Maharashtra, India.
authors.forename: Kunal S
authors.initials: KS
authors.lastname: Sethi
keywords: Coenzyme Q10; free radicals; periodontitis; reactive oxygen species; tea tree oil