title: The questioned p value: clinical, practical and statistical significance.
abstract: The use of p-value and statistical significance have been questioned since the early 80s in the last century until today. Much has been discussed about it in the field of statistics and its applications, especially in Epidemiology and Public Health. As a matter of fact, the p-value and its equivalent, statistical significance, are difficult concepts to grasp for the many health professionals some way involved in research applied to their work areas. However, its meaning should be clear in intuitive terms although it is based on theoretical concepts of the field of Statistics. This paper attempts to present the p-value as a concept that applies to everyday life and therefore intuitively simple but whose proper use cannot be separated from theoretical and methodological elements of inherent complexity. The reasons behind the criticism received by the p-value and its isolated use are intuitively explained, mainly the need to demarcate statistical significance from clinical significance and some of the recommended remedies for these problems are approached as well. It finally refers to the current trend to vindicate the p-value appealing to the convenience of its use in certain situations and the recent statement of the American Statistical Association in this regard.
authors.affiliation: Subeditora y revisora estadística, Medwave. Address: Villaseca 21 Of. 702, Ñuñoa, Santiago, Chile. Email: rosa.jimenez@medave.cl.
authors.forename: Rosa
authors.initials: R
authors.lastname: Jiménez-Paneque
mesh_terms: D003627:Data Interpretation, Statistical; D004812:Epidemiologic Methods; D004813:Epidemiology; D006282:Health Personnel; D006801:Humans; D008962:Models, Theoretical; D011634:Public Health / Q000706:statistics & numerical data*; D012107:Research Design