title: Pickle Flavors Relish in Drosophila Immunity.
abstract: Immune responses must be tightly controlled to avoid host damage. In Drosophila, two NF-κB signaling pathways, Toll and Imd, mediate host immune responses. In this issue of Cell Host & Microbe, Morris et al. (2016) introduce Pickle, a nuclear IκB that inhibits Drosophila immune signaling by modulating the NF-κB Relish.
authors.affiliation: BioMediTech, University of Tampere, 33520 Tampere, Finland.
authors.forename: Tiina Susanna
authors.initials: TS
authors.lastname: Salminen
authors.affiliation: BioMediTech, University of Tampere, 33520 Tampere, Finland; Department of Pediatrics, Tampere University Hospital, 33521 Tampere, Finland; PEDEGO Research Unit, Medical Research Center Oulu, University of Oulu, 90014 Oulu, Finland; Department of Children and Adolescents, Oulu University Hospital, 90220 Oulu, Finland. Electronic address: mika.ramet@uta.fi.
authors.forename: Mika
authors.initials: M
authors.lastname: Rämet
mesh_terms: D000818:Animals; D004330:Drosophila / Q000276:immunology*; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000276:immunology; D016328:NF-kappa B; D015398:Signal Transduction; D014157:Transcription Factors
chemical_list: D029721:Drosophila Proteins; D016328:NF-kappa B; D014157:Transcription Factors