title: Copper-Catalyzed Amidation of Primary and Secondary Alkyl Boronic Esters.
abstract: The oxidative copper-catalyzed cross-coupling of functionalized alkyl boronic esters with primary amides is reported. Through the identification of appropriate diketimine ligands, conditions for efficient coupling of both primary and secondary alkyl boronic esters with diverse primary amides, including acetamide, have been developed.
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
authors.forename: Luis M
authors.initials: LM
authors.lastname: Mori-Quiroz
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
authors.forename: Kirk W
authors.initials: KW
authors.lastname: Shimkin
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
authors.forename: Sina
authors.initials: S
authors.lastname: Rezazadeh
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
authors.forename: Ryan A
authors.initials: RA
authors.lastname: Kozlowski
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA. dawatson@udel.edu.
authors.forename: Donald A
authors.initials: DA
authors.lastname: Watson
keywords: NacNac ligand; alkyl boronic esters; amides; copper; cross-coupling