title: Screening outcomes of household contacts of multidrug-resistant tuberculosis patients in Peshawar, Pakistan.
abstract: OBJECTIVE
  To assess the profile of TB/multidrug-resistant TB (MDR-TB) among household contacts of MDR-TB patients.
  
  
  METHODS
  Close contacts of MDR-TB patients were traced in the cross-sectional study. Different clinical, radiological and bacteriological were performed to rule out the evidence of TB/MDR-TB.
  
  
  RESULTS
  Between January 2012 and December 2012, a total of 200 index MDR-TB patients were initiated on MDR-TB treatment, out of which home visit and contacts screening were conducted for 154 index cases. Of 610 contacts who could be studied, 41 (17.4%) were diagnosed with MDR-TB and 10 (4.2%) had TB. The most common symptoms observed were cough, chest pain and fever.
  
  
  CONCLUSIONS
  The high incidence of MDR-TB among close contacts emphasize the need for effective contact screening programme of index MDR-TB cases in order to cut the chain of transmission of this disease.
authors.affiliation: Post Graduate Medical Institute, Lady Reading Hospital, Peshawar, Pakistan; Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
authors.forename: Arshad
authors.initials: A
authors.lastname: Javaid
authors.affiliation: Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan. Electronic address: mali_smile2005@yahoo.com.
authors.forename: Mazhar Ali
authors.initials: MA
authors.lastname: Khan
authors.affiliation: Peshawar Medical College, Peshawar, Pakistan.
authors.forename: Mir Azam
authors.initials: MA
authors.lastname: Khan
authors.affiliation: Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
authors.forename: Sumaira
authors.initials: S
authors.lastname: Mehreen
authors.affiliation: Post Graduate Medical Institute, Lady Reading Hospital, Peshawar, Pakistan; Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
authors.forename: Anila
authors.initials: A
authors.lastname: Basit
authors.affiliation: Kohat University of Science and Technology, Kohat, Pakistan.
authors.forename: Raza Ali
authors.initials: RA
authors.lastname: Khan
authors.affiliation: Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ihtesham
authors.affiliation: Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
authors.forename: Irfan
authors.initials: I
authors.lastname: Ullah
authors.affiliation: Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
authors.forename: Afsar
authors.initials: A
authors.lastname: Khan
authors.affiliation: Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan.
authors.forename: Ubaid
authors.initials: U
authors.lastname: Ullah
keywords: Household contacts; MDR-TB; Pakistan; Peshawar; Tuberculosis