title: Diffuse Large B Cell Lymphoma in a Prosthetic Aortic Graft.
abstract: We describe the case of a 70-year-old man with Marfan Syndrome who was found to have Diffuse Large B Cell Lymphoma (DLBCL) within an ascending aortic graft, his native aortic arch and arch vessels. Ten years previously he had undergone a Bentall's Procedure for a dilated aortic root. He presented with a left middle cerebral artery stroke. Computed tomography (CT) scan revealed multiple filling defects within the aortic arch and branch vessels suggestive of thrombus. Following the stroke, his neurological deficit improved. A decision was made to perform an aortic arch replacement to reduce the risk of a further embolic event. Subsequent histopathology confirmed DLBCL. Intravascular DLBCL is an extremely rare entity but an important diagnosis to consider in patients with intra-aortic thrombus in proximity to prosthetic graft material.
authors.affiliation: Department of Cardiothoracic Surgery, Royal North Shore Hospital, Sydney, NSW, Australia. Electronic address: dovib@msn.com.
authors.forename: David
authors.initials: D
authors.lastname: Bell
authors.affiliation: Department of Cardiothoracic Surgery, Royal North Shore Hospital, Sydney, NSW, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Marshman
mesh_terms: D000368:Aged; D001011:Aorta / Q000473:pathology / Q000601:surgery; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000601:surgery; D008297:Male; D008382:Marfan Syndrome / Q000473:pathology / Q000601:surgery*; D019043:Vascular Neoplasms / Q000473:pathology / Q000601:surgery
keywords: Aortic arch; Lymphoma; Prosthetic graft; Thrombus