title: Lipid Profile in Cardiac Syndrome X: Association with Helicobacter pylori.
abstract: BACKGROUND
  Chronic inflammation caused by Helicobacter pylori (H.pylori) infection has a pathogenic role in Cardiac Syndrome X (CSX). In addition, it has shown that bacterial infection may affect blood lipids.
  
  
  OBJECTIVE
  To assess if H.pylori affects the level of lipid profile in CSX.
  
  
  METHODS
  Eighty-eight CSX patients and 97 healthy controls were enrolled. The Total Cholesterol (TC), Triglyceride (TG), Lipoprotein A (LP{A}), Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), Apoprotein A1 (APOA1), and Apoprotein B (APOB) was estimated colorimetrically. In addition, the presence of IgG antibody to H.pylori was tested in plasma samples by using enzyme linked immunosorbent assay method.
  
  
  RESULTS
  TC, LP{A}, LDL, APOA1 and APOB levels in CSX group were significantly higher than those of the control group (p<0.05). But, these parameters in H.pylori positive and H.pylori negative, among CSX and control groups were not significant.
  
  
  CONCLUSIONS
  Increased plasma level of lipid profile and H.pylori infection were associated with CSX; it seems that plasma lipid disorders have a significant role in the development of CSX.
authors.affiliation: Professor, Cellular and Molecular Research Center, Urmia University of Medical Sciences , Urmia, Iran; Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran .
authors.forename: Yousef
authors.initials: Y
authors.lastname: Rasmi
authors.affiliation: Student, Department of Biology, Faculty of Sciences, Payam-e Noor University , Tehran, Iran .
authors.forename: Javad
authors.initials: J
authors.lastname: Zeynalzadeh
authors.affiliation: Associate Professor, Department of Physiology, Faculty of Medicine, Urmia University of Medical Sciences , Urmia, Iran .
authors.forename: Alireza
authors.initials: A
authors.lastname: Shirpoor
authors.affiliation: Associate Professor, Department of Cardiology, Faculty of Medicine, Urmia University of Medical Sciences , Urmia, Iran .
authors.forename: Mirhossein
authors.initials: M
authors.lastname: Seyedmohammadzad
authors.affiliation: Associate Professor, Department of Biology, Faculty of Sciences, Payam-e Noor University , Tehran, Iran .
authors.forename: Reza
authors.initials: R
authors.lastname: Hajhosseini
keywords: Angiography; Chest Pain; Infection; Inflammation; Lipoprotein