title: [Diagnostics and treatment of hepatocellular adenomas].
abstract: - Hepatocellular adenomas are essentially benign tumours of the liver that occur mostly in women of reproductive age. - The four different subtypes described, which can be distinguished both radiologically and histopathologically, are: steatotic, inflammatory, β-catenin mutated and unclassified adenomas. These subtypes differ in the risk of complications.- Contrast-enhanced liver MRI is the best method for diagnostics and characterization of hepatocellular adenomas. - Possible complications include bleeding, rupture, and malignant degeneration of the hepatocellular adenoma. These complications are rare in adenomas < 5 cm. - Men with hepatocellular adenomas are at higher risk for malignant degeneration. - In women, lifestyle changes (cessation of oral contraceptive and weight reduction) can cause regression of the adenoma, which can prevent the necessity for liver surgery. - In pregnant women there is a risk of growth of hepatocellular adenoma. It is, therefore, it is recommended to check the tumour in pregnant women every 6-12 weeks using ultrasound.
authors.affiliation: Erasmus MC, Rotterdam.
authors.forename: A J
authors.initials: AJ
authors.lastname: Klompenhouwer
authors.forename: R A
authors.initials: RA
authors.lastname: de Man
authors.forename: M G J
authors.initials: MG
authors.lastname: Thomeer
authors.forename: M
authors.initials: M
authors.lastname: Doukas
authors.forename: J N M
authors.initials: JN
authors.lastname: IJzermans
mesh_terms: D018248:Adenoma, Liver Cell / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000628:therapy