title: Surgical management for squamous cell carcinoma of vulva.
abstract: To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analysis and the log rank test. The mean age was 60.78 years. Total vulvectomy was performed in all patients. Superficial and deep incision of bilateral inguinal lymphadenectomy was performed by separates incisions for SCC infiltrating more than 1mm. The average tumor size was 53 mm (10 to 140mm). Morbidity was 42.1%. Lateral resection margin ≥8mm was obtained in 57.1%. Eighteen patients benefited from adjuvant radiotherapy. The follow-up median was 19.4 months (6 to 61.5 month) with 05 recurrences in 12 months. The survival using the Kaplan-Meyer analysis at 5 years, was 62.1% (71.2%N(-) vs 46.7%N(+); p = 0.13). We identified two groups for locally advanced vulva cancer. Primary surgery keeps its place. Neo adjuvant radio chemotherapy followed by surgery is the alternative treatment for locally extensive lesions.
authors.affiliation: Service de Chirurgie Oncologique, Institut National d'Oncologie, Rabat, Maroc.
authors.forename: Ayi Kossigan
authors.initials: AK
authors.lastname: Amavi
authors.affiliation: Service de Chirurgie Oncologique, Institut National d'Oncologie, Rabat, Maroc.
authors.forename: Laurent
authors.initials: L
authors.lastname: Kouadio
authors.affiliation: Service de Chirurgie Oncologique, Institut National d'Oncologie, Rabat, Maroc.
authors.forename: Komlan
authors.initials: K
authors.lastname: Adabra
authors.affiliation: Service de Chirurgie Oncologique, Institut National d'Oncologie, Rabat, Maroc.
authors.forename: Kodjo
authors.initials: K
authors.lastname: Tengue
authors.affiliation: Chirurgie Générale, Viscérale, Chirurgie Oncologique, Clinique Médico-chirurgicale, Centre Hospitalier Universitaire Sylvanus Olympio, Lomé, Togo.
authors.forename: Fouad
authors.initials: F
authors.lastname: Tijami
authors.affiliation: Chirurgie Générale, Viscérale, Chirurgie Oncologique, Clinique Médico-chirurgicale, Centre Hospitalier Universitaire Sylvanus Olympio, Lomé, Togo.
authors.forename: Abdelouahed
authors.initials: A
authors.lastname: Jalil
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008197:Lymph Node Excision / Q000379:methods*; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods; D009364:Neoplasm Recurrence, Local; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D014844:Vulva / Q000473:pathology / Q000601:surgery*; D014846:Vulvar Neoplasms / Q000473:pathology / Q000601:surgery*
keywords: Locally advanced; cancer; surgery; vulva