title: Highlights of the 11th International Bordetella Symposium: from Basic Biology to Vaccine Development.
abstract: Pertussis is a severe respiratory disease caused by infection with the bacterial pathogen Bordetella pertussis The disease affects individuals of all ages but is particularly severe and sometimes fatal in unvaccinated young infants. Other Bordetella species cause diseases in humans, animals, and birds. Scientific, clinical, public health, vaccine company, and regulatory agency experts on these pathogens and diseases gathered in Buenos Aires, Argentina from 5 to 8 April 2016 for the 11th International Bordetella Symposium to discuss recent advances in our understanding of the biology of these organisms, the diseases they cause, and the development of new vaccines and other strategies to prevent these diseases. Highlights of the meeting included pertussis epidemiology in developing nations, genomic analysis of Bordetella biology and evolution, regulation of virulence factor expression, new model systems to study Bordetella biology and disease, effects of different vaccines on immune responses, maternal immunization as a strategy to prevent newborn disease, and novel vaccine development for pertussis. In addition, the group approved the formation of an International Bordetella Society to promote research and information exchange on bordetellae and to organize future meetings. A new Bordetella.org website will also be developed to facilitate these goals.
authors.affiliation: University of Maryland School of Medicine, Baltimore, Maryland, USA ncarbonetti@som.umaryland.edu.
authors.forename: Nicholas H
authors.initials: NH
authors.lastname: Carbonetti
authors.affiliation: Labor:Medizin Krefeld MVZ GmbH, Krefeld, Germany.
authors.forename: Carl Heinz
authors.initials: CH
authors.lastname: Wirsing von König
authors.affiliation: School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
authors.forename: Ruiting
authors.initials: R
authors.lastname: Lan
authors.affiliation: Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France.
authors.forename: Francoise
authors.identifier: http://orcid.org/0000-0002-5102-1704
authors.initials: F
authors.lastname: Jacob-Dubuisson
authors.affiliation: University of North Carolina-Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
authors.forename: Peggy A
authors.initials: PA
authors.lastname: Cotter
authors.affiliation: Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
authors.forename: Rajendar
authors.initials: R
authors.lastname: Deora
authors.affiliation: Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
authors.forename: Tod J
authors.initials: TJ
authors.lastname: Merkel
authors.affiliation: Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
authors.forename: Cécile A
authors.initials: CA
authors.lastname: van Els
authors.affiliation: Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France.
authors.forename: Camille
authors.initials: C
authors.lastname: Locht
authors.affiliation: IBBM, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.
authors.forename: Daniela
authors.initials: D
authors.lastname: Hozbor
authors.affiliation: CINDEFI (CONICET-UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.
authors.forename: Maria E
authors.initials: ME
authors.lastname: Rodriguez
mesh_terms: D000818:Animals; D001118:Argentina / Q000453:epidemiology; D001425:Bacterial Outer Membrane Proteins / Q000276:immunology; D001886:Bordetella pertussis / Q000276:immunology* / Q000502:physiology*; D006801:Humans; D007223:Infant; D010567:Pertussis Vaccine / Q000276:immunology*; D014611:Vaccination; D010566:Virulence Factors, Bordetella / Q000276:immunology; D014917:Whooping Cough / Q000453:epidemiology / Q000276:immunology* / Q000382:microbiology
chemical_list: D001425:Bacterial Outer Membrane Proteins; D010567:Pertussis Vaccine; D010566:Virulence Factors, Bordetella