title: Reemergence of Mycobacterium chimaera in Heater-Cooler Units despite Intensified Cleaning and Disinfection Protocol.
abstract: Invasive Mycobacterium chimaera infections after open-heart surgery have been reported internationally. These devastating infections result from aerosols generated by contaminated heater-cooler units used with extracorporeal circulation during surgery. Despite intensified cleaning and disinfection, surveillance samples from factory-new units acquired during 2014 grew nontuberculous mycobacteria after a median of 174 days.
authors.forename: Peter W
authors.initials: PW
authors.lastname: Schreiber
authors.forename: Stefan P
authors.initials: SP
authors.lastname: Kuster
authors.forename: Barbara
authors.initials: B
authors.lastname: Hasse
authors.forename: Cornelia
authors.initials: C
authors.lastname: Bayard
authors.forename: Christian
authors.initials: C
authors.lastname: Rüegg
authors.forename: Philipp
authors.initials: P
authors.lastname: Kohler
authors.forename: Peter M
authors.initials: PM
authors.lastname: Keller
authors.forename: Guido V
authors.initials: GV
authors.lastname: Bloemberg
authors.forename: Francesco
authors.initials: F
authors.lastname: Maisano
authors.forename: Dominique
authors.initials: D
authors.lastname: Bettex
authors.forename: Maximilian
authors.initials: M
authors.lastname: Halbe
authors.forename: Rami
authors.initials: R
authors.lastname: Sommerstein
authors.forename: Hugo
authors.initials: H
authors.lastname: Sax
mesh_terms: D000336:Aerosols / Q000009:adverse effects; D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D003428:Cross Infection / Q000209:etiology / Q000382:microbiology; D004203:Disinfection; D004865:Equipment and Supplies, Hospital / Q000382:microbiology*; D006801:Humans; D009161:Mycobacterium / Q000145:classification / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000209:etiology / Q000382:microbiology; D013193:Stainless Steel
chemical_list: D000336:Aerosols; D013193:Stainless Steel
keywords: Mycobacterium chimaera; bacteria; disinfection; heater–cooler units; hospital equipment; hospital infections; nontuberculous mycobacterial infections; nosocomial infections; tuberculosis and other mycobacteria