title: [Severe hemorrhagic forms of Rift Valley fever: about 5 cases].
abstract: Rift Valley fever (RVF) is an arbovirus caused by an RNA virus belonging to family Bunyaviridae (genus phlebovirus). It is a zoonosis that primarily affects animals but it also has the capacity to infect humans, either by handling meat, runts of sick animals or, indirectly, by the bite of infected mosquitoes (Aedes sp, Anopheles sp, Culex sp). In most cases, RVF infection in humans is asymptomatic, but it can also manifest as moderate febrile syndrome with a favorable outcome. However, some patients may develop hemorrhagic syndrome and/or neurological damages with a fatal evolution. We present a case study of the development of 5 patients with RVF associated with hemorrhagic fever syndrome admitted to the internal medicine department at National Hospital Center in Nouakchott (Mauritania), in October 2015. The outcome was favorable for two of the five patients. The other 3 died, two of hemorrhagic shock and one of septic shock.
authors.affiliation: Service des Laboratoires, Centre Hospitalier National de Nouakchott, Mauritanie; Faculté de Médecine de Nouakchott, Mauritanie.
authors.forename: Mohamed Lemine Ould
authors.initials: ML
authors.lastname: Salem
authors.affiliation: Faculté de Médecine de Nouakchott, Mauritanie; Service de Médecine interne, Centre Hospitalier National de Nouakchott, Mauritanie.
authors.forename: Sidi El Wafi Ould
authors.initials: Sel W
authors.lastname: Baba
authors.affiliation: Faculté de Médecine de Nouakchott, Mauritanie; Institut National d'Hépato-virologie de Nouakchott, Mauritanie.
authors.forename: Fatimetou Zahra
authors.initials: FZ
authors.lastname: Fall-Malick
authors.affiliation: Service de Médecine interne du Centre Hospitalier d'Aïoun, Mauritanie.
authors.forename: Boushab Mohamed
authors.initials: BM
authors.lastname: Boushab
authors.affiliation: Faculté de Médecine de Nouakchott, Mauritanie.
authors.forename: Sidi Mohamed
authors.initials: SM
authors.lastname: Ghaber
authors.affiliation: Service de Médecine interne, Centre Hospitalier National de Nouakchott, Mauritanie.
authors.forename: Abdelwedoud
authors.initials: A
authors.lastname: Mokhtar
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D005260:Female; D006801:Humans; D008297:Male; D008435:Mauritania; D012295:Rift Valley Fever / Q000150:complications / Q000503:physiopathology*; D012771:Shock, Hemorrhagic / Q000209:etiology*; D012772:Shock, Septic / Q000209:etiology*; D055815:Young Adult; D015047:Zoonoses / Q000150:complications / Q000503:physiopathology*
keywords: Mauritania; Rift Valley fever; hemorrhagic syndrome