title: Robotic surgical management of endometrial cancer in octogenarians and nonagenarians: analysis of perioperative outcomes and review of the literature.
abstract: The primary aim of this article is to report the outcomes of octogenarians and nonagenarians who have undergone robotic surgery for endometrial cancer. A multi-institutional research consortium was created to evaluate the utility of robotics for gynecologic surgery (benign and malignant). IRB approval was obtained at each institution. A multi-institutional HIPPA compliant database was then created and analyzed for all patients that underwent robotic-assisted surgery with staging for endometrial cancer between the April 2003 and January 2009. In total, 395 patients were identified. A subset of patients between the ages of 80 and 95 years were then identified and analyzed for demographic data and perioperative outcomes. Twenty-seven patients in this age group were identified who underwent robotic-assisted hysterectomy and staging. The median age was 84, and median body mass index was 28. Comorbidities such as diabetes mellitus and hypertension were identified in 22 and 74% of patients, respectively. Over one-half (56%) of the patients reported a prior abdominal surgery. Final pathological analysis demonstrated that 88% of all patients had either Stage I or II disease. The median operative time was 192 min. The median estimated blood loss was 50 cc, and the median lymph node count was 16. The median hospital stay was 1.0 day. The overall intraoperative and postoperative complication rate was 7.4 and 33%, respectively. No patient received a blood transfusion. There was one conversion to laparotomy (3.7%). A comparison of the outcomes of the elderly cohort to those of all patients in the database (control group) revealed that there was no statistically significant difference between the groups in terms of operative time, blood loss, hospital stay, nodal yield, or conversion rate. Intraoperative complications were statistically similar between the groups; however, postoperative complications were significantly higher in the elderly cohort. We conclude that robotic surgery is safe, feasible, and expands surgical options for octogenarians and nonagenarians diagnosed with endometrial cancer. Age should not be considered a contraindication for robotic surgical management of patients with endometrial cancer.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, 250 East Superior Street, Suite 5-2168, Chicago, IL, 60611, USA. mpatricklowe@mac.com.
authors.forename: M Patrick
authors.initials: MP
authors.lastname: Lowe
authors.affiliation: Department of Obstetrics and Gynecology, University of Tennessee Health Science Center and West Clinic, Memphis, TN, USA.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department of Obstetrics and Gynecology, Aurora Health Center, University of Wisconsin School of Medicine and Public Health, Milwaukee, WI, USA.
authors.forename: Peter R
authors.initials: PR
authors.lastname: Johnson
authors.affiliation: Department of Obstetrics and Gynecology, Aurora Health Center, University of Wisconsin School of Medicine and Public Health, Milwaukee, WI, USA.
authors.forename: Scott A
authors.initials: SA
authors.lastname: Kamelle
authors.affiliation: Chattanooga Gynecologic Oncology, University of Tennessee, Chattanooga, TN, USA.
authors.forename: Donald H
authors.initials: DH
authors.lastname: Chamberlain
authors.affiliation: Department of Obstetrics and Gynecology, University of Tennessee Health Science Center and West Clinic, Memphis, TN, USA.
authors.forename: Todd D
authors.initials: TD
authors.lastname: Tillmanns
keywords: Elderly; Endometrial cancer; Minimally invasive surgery; Octogenarians; Robotic hysterectomy; Robotic surgery; Uterine cancer