title: Influence of change in surgical practice for benign thyroid disease on postsurgical outcome-Single-center experience in 1400 patients.
abstract: OBJECTIVE
  To evaluate the rate of surgical complications during the change from subtotal resection to hemithyroidectomy or thyroidectomy over a period of 17 years.
  
  
  METHODS
  All operations for benign goiter at our hospital were analyzed for the periods 1996-2002 (Group 1) and 2003-2012 (Group 2). The groups were compared for recurrent laryngeal nerve damage, hypocalcemia, and other surgical complications directly postoperatively.
  
  
  RESULTS
  In total, 1462 patients were operated on for goiter between 1996 and 2012. There were 1219 patients who underwent a primary thyroid operation, whereas 50 patients had surgery for recurrence. Postoperative histology revealed thyroid cancer in 193 patients (13.2%). In Group 1, 42.7% of all operated lobes were performed as lobectomies and 57.3% as subtotal resections; in Group 2, 74.4% were performed as lobectomies and 25.6% as subtotal resections. No differences were found for reduced vocal cord function (2.4% vs. 1.9%, p = 0.746) and recurrent laryngeal nerve paralysis in the postoperative laryngoscopy (2.9% vs. 1.8%, p = 0.675). Postoperative hypoparathyroidism was detected in 13.66% in Group 1 and in 19.80% in Group 2 after bilateral resections (p = 0.037). There was no difference in the rate of reoperations for cancer between both groups (43.4% vs. 52.1%, p = 0.182).
  
  
  CONCLUSIONS
  Surgical practice changed from subtotal to lobectomies for benign goiter over a period of 17 years without change in laryngeal nerve damage but with increasing rates of postoperative hypocalcemia.
authors.affiliation: Department of General, Visceral and Vascular Surgery, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany. Electronic address: urte.kunz-zurbuchen@charite.de.
authors.forename: Urte
authors.initials: U
authors.lastname: Kunz-Zurbuchen
authors.affiliation: Department of General, Visceral and Vascular Surgery, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
authors.forename: Heinz Johannes
authors.initials: HJ
authors.lastname: Buhr
authors.affiliation: Department of General and Visceral Surgery Wuppertal, Petrus - Hospital, Wuppertal, Germany.
authors.forename: Hubert G
authors.initials: HG
authors.lastname: Hotz
authors.affiliation: Department of General, Visceral and Vascular Surgery, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
authors.forename: Martin E
authors.initials: ME
authors.lastname: Kreis
authors.affiliation: Department of General, Visceral and Vascular Surgery, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
authors.forename: Kai S
authors.initials: KS
authors.lastname: Lehmann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006042:Goiter / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D010818:Practice Patterns, Physicians' / Q000639:trends*; D012189:Retrospective Studies; D013965:Thyroidectomy / Q000379:methods* / Q000639:trends; D016896:Treatment Outcome; D055815:Young Adult
keywords: goiter; subtotal resection; thyroidectomy