title: [Autoimmune myopathy associated with statin use].
abstract: It is well known that statins can have a toxic effect on musculature, but less widely known that they can also trigger progressive autoimmune myopathy. Statin-associated autoimmune myopathy is characterised by proximal muscle weakness, antibodies to 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) in serum, and necrosis without lymphocytic infiltration on muscle biopsy.
authors.affiliation: Nevrologisk avdeling Sørlandet sykehus, Kristiansand og Klinisk institutt 1 Universitetet i Bergen.
authors.forename: Unn
authors.initials: U
authors.lastname: Ljøstad
authors.affiliation: Nevrologisk avdeling Sørlandet sykehus, Kristiansand og Klinisk institutt 1 Universitetet i Bergen og Avdeling for rehabilitering Sørlandet sykehus, Kristiansand.
authors.forename: Åse
authors.initials: Å
authors.lastname: Mygland
mesh_terms: D000214:Acyl Coenzyme A / Q000276:immunology; D000368:Aged; D000369:Aged, 80 and over; D001327:Autoimmune Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology
chemical_list: D000214:Acyl Coenzyme A; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors