title: [Analysis on molecular genetic evolution of Banna virus based on the 12thsegment].
abstract: Objective:To understand the evolution characteristics of Banna viruses (BAVs) isolated worldwide from 1980 to 2012.Methods:In this study, a phylogenetic analysis using Bayesian Markov Chain Monte Carlo simulations was conducted on all available 12thsegment of genes of BAVs isolated worldwide from 1980 to 2012 to investigate the evolutionary and epidemiologic dynamics of BAVs.Results:The Bayesian phylogenetic analysis of BAVs revealed that the common ancestor of BAVs appeared 315 (95%HPD: 63-619) years ago. The evolutionary rate of BAV based on the 12thsegment gene was estimated to be 2.33×10-3(95%HPD: 2.84× 10-4-8.52×10-3) substitution per site per year, indicating BAV belong to an emerging arbovirus with rapid evolution.Conclusion:The evolution of emerging BAVs is rapid and the distribution of BAVs has expanded with new variant being detected, so it is necessary to enhance the surveillance to fully understand the natural distribution and pathogenicity of BAVs.
authors.affiliation: School of Life Sciences, Shandong University of Technology, Zibo 255000, China; Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: X Y
authors.initials: XY
authors.lastname: Gao
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: S H
authors.initials: SH
authors.lastname: Fu
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: M H
authors.initials: MH
authors.lastname: Li
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Y G
authors.initials: YG
authors.lastname: Zhai
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: W S
authors.initials: WS
authors.lastname: Meng
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: X X
authors.initials: XX
authors.lastname: Sun
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: H Y
authors.initials: HY
authors.lastname: Wang
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Lyu
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: X X
authors.initials: XX
authors.lastname: Shen
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Y X
authors.initials: YX
authors.lastname: Cao
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Y
authors.initials: Y
authors.lastname: He
authors.affiliation: Department of Virual Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: G D
authors.initials: GD
authors.lastname: Liang
mesh_terms: D001499:Bayes Theorem; D018162:Coltivirus / Q000235:genetics* / Q000472:pathogenicity; D019143:Evolution, Molecular; D006801:Humans; D008390:Markov Chains; D009010:Monte Carlo Method; D010802:Phylogeny