title: Helicobacter pylori status among patients undergoing gastroscopy in rural northern Alberta.
abstract: OBJECTIVE
  To determine the Helicobacter pylori status of patients who underwent gastroscopy.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  Peace River Community Health Centre in rural northwestern Alberta.
  
  
  METHODS
  Data were collected from patients who had a gastroscopy performed by either of 2 family physicians between January 1, 2011, and December 31, 2012.
  
  
  METHODS
  The proportion of patients who had positive test results for H pylori overall and among first-time gastroscopy patients. For first-time gastroscopy patients, the associations between H pylori infection and patient age, sex, residence, and procedural indications and findings were explored.
  
  
  RESULTS
  A total of 251 gastroscopies were conducted in 229 unique patients during the study period. Overall, 12.4% (95% CI 8.3% to 16.4%) of patients had positive results for H pylori and among the 159 first-time gastroscopy patients, 17.6% (95% CI 11.7% to 23.5%) had positive test results for H pylori. Helicobacter pylori status did not differ significantly by geography, sex, or age. The prevalence of H pylori was higher among patients with H pylori-related indications for gastroscopy (such as dyspepsia and upper gastrointestinal tract bleeding) than among patients with other indications; however, H pylori infection was not statistically significantly greater in patients diagnosed with peptic ulcer disease.
  
  
  CONCLUSIONS
  The prevalence of H pylori infection among patients undergoing gastroscopy in rural northern Alberta appears lower than other Canadian estimates. In regions with low H pylori rates, patients with dyspepsia might be better served by acid suppression and nonsteroidal anti-inflammatory drug cessation before investigating for H pylori infection. Population-based research is required to further describe regional differences in H pylori rates.
authors.affiliation: Medical student at the University of Alberta in Edmonton at the time of the study, and is now an emergency medicine resident.
authors.forename: Isabelle N
authors.initials: IN
authors.lastname: Colmers-Gray
authors.affiliation: Biostatistician in the Alberta Research Centre for Health Evidence in the Department of Pediatrics at the University of Alberta.
authors.forename: Ben
authors.initials: B
authors.lastname: Vandermeer
authors.affiliation: Family physician in the Peace River Community Health Centre.
authors.forename: Robert I
authors.initials: RI
authors.lastname: Greidanus
authors.affiliation: Associate Professor in the Department of Family Medicine at the University of Alberta and a family physician in Peace River. mkolber@ualberta.ca.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Kolber
mesh_terms: D000328:Adult; D000368:Aged; D000416:Alberta; D004415:Dyspepsia / Q000150:complications; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000150:complications; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000150:complications; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D012189:Retrospective Studies; D013270:Stomach / Q000382:microbiology* / Q000473:pathology
chemical_list: D054328:Proton Pump Inhibitors