title: The six obesity indices, which one is more compatible with metabolic syndrome? A population based study.
abstract: OBJECTIVE
  The present study was conducted to determine the best discriminators in the diagnosis of the metabolic syndrome (MetS) among six obesity indexes. Furthermore the optimal cutoff points for all obesity indexes were determined.
  
  
  METHODS
  The baseline data of 5910 subjects of Haraz cohort study which was conducted in northern Iran were analyzed. Receiver operating characteristic (ROC) analyses were separately performed to determine discriminatory power of six obesity indexes, including, body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR), waist to height ratio (WHtR), abdominal volume index (AVI) and conicity index (CI) for diagnosis of at least two other components of MetS. Youden index was used to determine the optimal cutoff points.
  
  
  RESULTS
  While the optimal cutoff points in men were 26.0kg/m2for BMI, 90cm for WC, 0.90 for WHR, 0.53 for WHtR, 16.6 (cm2) for AVI and 1.24(m32/kg12) for CI, the optimal values in women were 29.0kg/m2for BMI, 91cm for WC, 0.86 for WHR, 0.58 for WHtR, 17.0(cm2) for AVI and 1.23 (m32/kg12) for CI. The prevalence of overweight or obesity was 46.1% to 54.1% in women and 49.5% to 53.6% in men based on various obesity indexes. The area under the ROC curves (AUCs) varied from 0.671(0.651-0.690) for CI to 0.718(0.700-0.736) for WC in men and from 0.668 (0.646-0.690) for BMI to 0.755(0.735-0.774) for WHR and CI in women.
  
  
  CONCLUSIONS
  Except for CI in men and BMI in women, other obesity indexes were good discriminator in the diagnosis of the MetS.
authors.affiliation: Department of Social Medicine, Zanjan University of Medical Sciences, Zanjan, Iran; Gastrointestinal and Liver Diseases Research Center (GILDRC), Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Nima
authors.initials: N
authors.lastname: Motamed
authors.affiliation: Gastrointestinal and Liver Diseases Research Center (GILDRC), Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Masoudreza
authors.initials: M
authors.lastname: Sohrabi
authors.affiliation: Gastrointestinal and Liver Diseases Research Center (GILDRC), Iran University of Medical Sciences, Tehran, Iran; Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Poustchi
authors.affiliation: Amol Health Network, Mazandaran University of Medical Sciences, Amol, Iran.
authors.forename: Mansooreh
authors.initials: M
authors.lastname: Maadi
authors.affiliation: Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Malek
authors.affiliation: Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Keyvani
authors.affiliation: Amol Health Network, Mazandaran University of Medical Sciences, Amol, Iran.
authors.forename: Mahboobeh Safaean
authors.initials: MS
authors.lastname: Amoli
authors.affiliation: Gastrointestinal and Liver Diseases Research Center (GILDRC), Iran University of Medical Sciences, Tehran, Iran. Electronic address: zamani.farhad@gmail.com.
authors.forename: Farhad
authors.initials: F
authors.lastname: Zamani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000378:metabolism; D007492:Iran / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism*; D008875:Middle Aged; D009765:Obesity / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism*; D011159:Population Surveillance; D012307:Risk Factors; D055105:Waist Circumference / Q000502:physiology*; D065927:Waist-Height Ratio; D049629:Waist-Hip Ratio; D055815:Young Adult
keywords: Cutoff points; Metabolic syndrome; Obesity indexes