title: Iron deficiency among apparently healthy children aged 6 to 24 months in Ibadan, Nigeria.
abstract: Iron deficiency remains a global public health challenge, with a higher burden in children in the tropics. When it occurs early in life, it may have long-term effects on neurodevelopment. The aims of this study were to assess the iron status of children aged 6-24 months, to determine the prevalence of iron deficiency and its associated factors in Ibadan, Nigeria. The authors conducted a cross-sectional study between March and June 2014. A total of 202 apparently healthy children aged between 6 and 24 months attending 2 major immunization clinics in Ibadan were included. A questionnaire was used to collect information on sociodemographic characteristics, pregnancy and birth history, and nutritional history. Physical examination was carried out on all the subjects, and serum ferritin level was determined using an enzyme-linked immunosorbent assay (ELISA) technique. Iron deficiency was defined using a cutoff value of <30 µg/L. Fifty-nine children (29.2%) had iron deficiency. No clinical features were found to be significantly associated with iron deficiency. Iron deficiency was associated with breastfeeding (P = .020) and younger age (P = .015) in the study population. One hundred and forty-three (70.8%) of the study participants had anemia, and 39 (19.3%) had iron deficiency anemia. The prevalence of iron deficiency among apparently healthy children aged 6-24 months in Ibadan, Nigeria, is high. There is the need for a national policy on routine screening for iron deficiency and iron supplementation for infants and young children as recommended by the World Health Organization.
authors.affiliation: a Department of Paediatrics , University College Hospital , Ibadan , Nigeria.
authors.forename: Olufunke Tolulope
authors.initials: OT
authors.lastname: Owa
authors.affiliation: b Department of Paediatrics , College of Medicine, University of Ibadan , Ibadan , Nigeria.
authors.forename: Biobele J
authors.initials: BJ
authors.lastname: Brown
authors.affiliation: c Department of Paediatrics and Child Health , Obafemi Awolowo University , Ile-Ife , Nigeria.
authors.forename: Oluwagbemiga O
authors.initials: OO
authors.lastname: Adeodu
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000453:epidemiology*; D001942:Breast Feeding; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D007223:Infant; D008297:Male; D009549:Nigeria; D011247:Pregnancy; D015995:Prevalence; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
chemical_list: D005293:Ferritins
keywords: Breastfeeding; Ibadan Nigeria; healthy children; iron deficiency