title: Overview of different scoring systems in Fournier's Gangrene and assessment of prognostic factors.
abstract: OBJECTIVE
  In this study we aimed to evaluate prognostic factors for the survival of patients with Fournier's gangrene (FG), and overview different validated scoring systems for outcome prediction.
  
  
  METHODS
  We retrospectively analyzed the data of 39 patients treated for FG in our clinic. Data were collected on medical history, symptoms, physical examination findings, vital signs, laboratory parameters at admission and at the end of treatment, timing and extent of surgical debridement, and the antibiotic treatment used. The Fournier's Gangrene Severity Index (FGSI) and Charlson Comorbidity Index (CCI) were used to predict outcome. The data were analyzed in relation with the survival of the patients. Mann-Whitney U test, chi -square test, Wilcoxon signed rank test, and Cox regression analysis were used for the statistical analysis.
  
  
  RESULTS
  Of 39 patients analyzed, 8 (20.5%) died and 31 (79.5%) survived. The median FGSI score on admission was 2 (0-9) for the survivors and 6 (2-14) for the non-survivors (p=0.004). The median CCI scores of the survivors and non-survivors were 2 (0-10) and 6.5 (5-11), respectively (p=0.001). Except for urea, albumin and hematocrit levels, no significant differences were found between survivors and non-survivors for other laboratory parameters on admission. Lower albumin levels and advanced age were found to be associated with mortality.
  
  
  CONCLUSIONS
  High blood urea, low albumin, and low hematocrit levels were associated with poor prognosis. High CCI and FGSI scores could be associated with a poor prognosis in patients with FG.
authors.affiliation: Clinic of Urology, Ankara Training and Research Hospital, Ankara, Turkey.
authors.forename: Ömer Gökhan
authors.initials: ÖG
authors.lastname: Doluoğlu
authors.affiliation: Clinic of Urology, Ankara Training and Research Hospital, Ankara, Turkey.
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Karagöz
authors.affiliation: Clinic of Urology, Ankara Training and Research Hospital, Ankara, Turkey.
authors.forename: Muhammet Fatih
authors.initials: MF
authors.lastname: Kılınç
authors.affiliation: Clinic of Urology, Ankara Training and Research Hospital, Ankara, Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Karakan
authors.affiliation: Clinic of Urology, Ankara Training and Research Hospital, Ankara, Turkey.
authors.forename: Cem Nedim
authors.initials: CN
authors.lastname: Yücetürk
authors.affiliation: Department of Urology, Afyon Kocatepe University School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Haşmet
authors.initials: H
authors.lastname: Sarıcı
authors.affiliation: Clinic of Urology, Ankara Training and Research Hospital, Ankara, Turkey.
authors.forename: Berat Cem
authors.initials: BC
authors.lastname: Özgür
authors.affiliation: Department of Urology, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Eroğlu
keywords: Fournier’s gangrene; genitalia; mortality; prognosis; risk factors