title: [Ito hypomelanosis: Four case reports].
abstract: Ito hypomelanosis is a rare neurocutaneous condition. We report on four observations in infants aged between 8 and 20 months. They all presented with epilepsy, psychomotor delay, and diffuse hypomelanosis. The electroencephalograms showed diffuse irritative abnormalities. Brain imaging was normal in two infants and showed hemispheric atrophy in another case. Despite antiepileptic treatment and physical therapy, no significant progression was noted and all children continued to have drug-resistant epilepsy and psychomotor delay.
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal.
authors.forename: S D
authors.initials: SD
authors.lastname: Sagna
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal; Service de neurologie, Yaoundé, Cameroun.
authors.forename: P
authors.initials: P
authors.lastname: Mbonda
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal. Electronic address: ngouille@hotmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Ndiaye
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal.
authors.forename: A D
authors.initials: AD
authors.lastname: Sow
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal.
authors.forename: A M
authors.initials: AM
authors.lastname: Basse
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal.
authors.forename: M S
authors.initials: MS
authors.lastname: Diop
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal.
authors.forename: N S
authors.initials: NS
authors.lastname: Diagne
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal.
authors.forename: A G
authors.initials: AG
authors.lastname: Diop
authors.affiliation: Unité de dermatologie, HEAR, Dakar, Sénégal.
authors.forename: A
authors.initials: A
authors.lastname: Kane
authors.affiliation: Service de neurologie, CHU Fann, BP 5035, Dakar, Sénégal.
authors.forename: M M
authors.initials: MM
authors.lastname: Ndiaye
mesh_terms: D001284:Atrophy / Q000000981:diagnostic imaging; D001921:Brain / Q000473:pathology; D002658:Developmental Disabilities / Q000150:complications*; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications*; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000150:complications*; D007223:Infant; D008297:Male