title: Multidrug-resistant Staphylococcus spp and its impact on patient outcome.
abstract: In order to analyze the outcomes, clinical features, and resistance of Staphylococcus spp infections, a prospective cohort study was conducted at a 234-bed, tertiary care teaching hospital. Multidrug-resistant (MDR) infections were associated with increased mortality and length of hospital stay (LOS), whereas methicillin resistance (MRS) was correlated with prolonged LOS after infection. These data highlight the importance of infection control and antibiotic stewardship to prevent the emergence and spread of MRS and MDR health care-associated infections.
authors.affiliation: Universidade Federal de Ciências da Saúde, Porto Alegre, RS, Brazil.
authors.forename: Janine M
authors.initials: JM
authors.lastname: Rauber
authors.affiliation: Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brazil; Hospital Santa Cruz, Santa Cruz do Sul, RS, Brazil.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Carneiro
authors.affiliation: Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brazil.
authors.forename: Guilherme H O
authors.initials: GH
authors.lastname: Arnhold
authors.affiliation: Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brazil.
authors.forename: Monica B
authors.initials: MB
authors.lastname: Zanotto
authors.affiliation: Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brazil.
authors.forename: Patrícia R
authors.initials: PR
authors.lastname: Wappler
authors.affiliation: Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brazil.
authors.forename: Barbara
authors.initials: B
authors.lastname: Baggiotto
authors.affiliation: Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brazil.
authors.forename: Andréia R M
authors.initials: AR
authors.lastname: Valim
authors.affiliation: Universidade Federal de Ciências da Saúde, Porto Alegre, RS, Brazil. Electronic address: pedro_dazevedo@yahoo.com.br.
authors.forename: Pedro A
authors.initials: PA
authors.lastname: d'Azevedo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology* / Q000401:mortality; D013210:Staphylococcus / Q000187:drug effects*; D016019:Survival Analysis; D062606:Tertiary Care Centers; D016896:Treatment Outcome
keywords: Length of stay; Methicillin resistance; Mortality; Multidrug resistance; Staphylococcal infections