title: The relation between angioarchitectural factors of developmental venous anomaly and concomitant sporadic cavernous malformation.
abstract: BACKGROUND
  Past studies found that cerebral developmental venous anomaly (DVA) is often concurrent with cavernous malformation (CM). But the reason of the concurrency remains unknown. The purpose of this study was to confirm whether angioarchitectural factors relate to the concurrence and which angioarchitectural factors can induce the concurrency.
  
  
  METHODS
  DVA cases were selected from the records of the same 3.0 T MR. The DVA cases was divided into two group which are DVA group and DVA concurrent with CM group. 8 angioarchitectural factors of the DVAs were selected and measured. Statistical analysis was performed by the Pearson chi-square statistic,analysis of variance (ANOVA) and multi-factor logistic regression analysis.
  
  
  RESULTS
  Five hundred three DVA lesions were found and 76 CM lesions coexisting with DVA. In the single factor analysis, all the 8 angioarchitectural factors of DVA were related to the concurrency. In the multivariate analysis, 6 angioarchitectural factors. Result of multi-factor logistic regression analysis is Logit(P) = -4.858-0.932(Location) + 1.616(Direction) + 1.757(Torsion) + 0.237(Number) + 2.119(Stenosis rate of medullary vein)-0.015(Angle), goodness of fit is 90.1 %.
  
  
  CONCLUSIONS
  The angioarchitectural factors of DVA are related to the concurrency of DVA and CM. 6 angioarchitectural factors may induce the concurrency.
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Tengfei
authors.initials: T
authors.lastname: Yu
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Xing
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Xiangjiang
authors.initials: X
authors.lastname: Lin
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Chuanfeng
authors.initials: C
authors.lastname: Bai
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Jizong
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Junting
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Liwei
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wu
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Shuo
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China.
authors.forename: Yuanli
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital,Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, 6 Tiantan Xili, Chongwen District, Beijing, 100050, People's Republic of China. mengguolu@sina.com.
authors.forename: Guolu
authors.initials: G
authors.lastname: Meng
keywords: Angioarchitectural factors; Cavernous malformation (CM); Contrast-enhanced magnetic resonance imaging; Developmental venous anomaly (DVA)