title: Epigenetic Profiling of CUP.
abstract: DNA methylation profiling may have potential in unmasking the origin of tumors classified as cancer of unknown primary. A diagnostic assay developed by the researchers, EPICUP, predicted the primary tumor site in 87% of 216 cases, and these predictions were subsequently verified through various tests, including immunohistochemistry.
mesh_terms: D019175:DNA Methylation / Q000235:genetics*; D044127:Epigenesis, Genetic / Q000235:genetics*; D015894:Genome, Human; D006801:Humans; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology; D013030:Spain