title: The Impact of Selected Fluoridated Toothpastes on Dental Erosion in Profilometric Measurement.
abstract: BACKGROUND
  Some fluoridated toothpastes, available commercially, are described to have a protective effect against dental erosion.
  
  
  OBJECTIVE
  To evaluate the influence of the selected marketed toothpastes on the human enamel exposed to acid beverages.
  
  
  METHODS
  Enamel specimens from extracted human teeth were prepared (n = 40). Specimens were randomly divided into 10 experimental groups, 4 specimens each, which were subjected to acid challenge for 10 min using orange juice (pH 3.79) or Pepsi Cola (pH 2.58) and then immersed for 2 min into a slurry of five marketed toothpastes with distilled water (1 : 3 w/w). The tested toothpastes contained 1450 or 5000 ppm fluoride, CPP-ACP with 900 ppm fluoride, 1450 ppm fluoride with potassium nitrate 5%, all of them as sodium fluoride, and 700 ppm fluoride as amine and sodium fluoride with 3500 ppm SnCl2. Enamel roughness (Ra parameter) by contact profilometer at baseline and after exposure onto soft drinks and slurry was measured.
  
  
  RESULTS
  Exposure to both beverages caused a similar increase of enamel surface roughness. After the specimens immersion into slurries of toothpastes with 1450 or 5000 ppm fluoride, 1450 ppm fluoride with potassium nitrate 5% and CPP-ACP with 900 ppm fluoride the significant decrease of Ra values were found, reaching the baseline values. However, toothpaste with 700 ppm fluoride and 3500 ppm SnCl2 did not cause any fall in Ra value, probably due to other mechanism of action.
  
  
  CONCLUSIONS
  Within the limitation of the study we can conclude that the sodium fluoride toothpastes are able to restore the surface profile of enamel exposed shortly to acidic soft drinks.
authors.affiliation: Department of Conservative Dentistry and Pedodontics, Wroclaw Medical University, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Fita
authors.affiliation: Department of Conservative Dentistry and Pedodontics, Wroclaw Medical University, Poland.
authors.forename: Urszula
authors.initials: U
authors.lastname: Kaczmarek
mesh_terms: D002253:Carbonated Beverages; D032084:Citrus sinensis; D003743:Dental Enamel / Q000187:drug effects*; D000067030:Fruit and Vegetable Juices; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D009566:Nitrates / Q000494:pharmacology; D017680:Potassium Compounds / Q000494:pharmacology; D012969:Sodium Fluoride / Q000494:pharmacology*; D014077:Tooth Erosion / Q000517:prevention & control*; D014081:Tooth Extraction; D014100:Toothpastes / Q000494:pharmacology*
chemical_list: D009566:Nitrates; D017680:Potassium Compounds; D014100:Toothpastes; D012969:Sodium Fluoride; C023844:potassium nitrate
keywords: dental erosion; fluoridated toothpastes; profilometry