title: My46: a Web-based tool for self-guided management of genomic test results in research and clinical settings.
abstract: A major challenge to implementing precision medicine is the need for an efficient and cost-effective strategy for returning individual genomic test results that is easily scalable and can be incorporated into multiple models of clinical practice. My46 is a Web-based tool for managing the return of genetic results that was designed and developed to support a wide range of approaches to disclosing results, ranging from traditional face-to-face disclosure to self-guided models. My46 has five key functions: set and modify results-return preferences, return results, educate, manage the return of results, and assess the return of results. These key functions are supported by six distinct modules and a suite of features that enhance the user experience, ease site navigation, facilitate knowledge sharing, and enable results-return tracking. My46 is a potentially effective solution for returning results and supports current trends toward shared decision making between patients and providers and patient-driven health management.Genet Med 19 4, 467-475.
authors.affiliation: Department of Pediatrics, University of Washington, Seattle, Washington, USA.|Treuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, Washington, USA.
authors.forename: Holly K
authors.identifier: 0000-0003-1005-5008
authors.initials: HK
authors.lastname: Tabor
authors.affiliation: Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.|Department of Paediatric Laboratory Medicine, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: Seema M
authors.identifier: 0000-0002-5427-8839
authors.initials: SM
authors.lastname: Jamal
authors.affiliation: Department of Pediatrics, University of Washington, Seattle, Washington, USA.
authors.forename: Joon-Ho
authors.identifier: 0000-0002-9635-8618
authors.initials: JH
authors.lastname: Yu
authors.affiliation: Treuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, Washington, USA.
authors.forename: Julia M
authors.identifier: 0000-0002-7694-1881
authors.initials: JM
authors.lastname: Crouch
authors.affiliation: Department of Pediatrics, University of Washington, Seattle, Washington, USA.
authors.forename: Aditi G
authors.identifier: 0000-0002-3938-5652
authors.initials: AG
authors.lastname: Shankar
authors.affiliation: Department of Pediatrics University of Utah, Salt Lake City, Utah, USA.
authors.forename: Karin M
authors.initials: KM
authors.lastname: Dent
authors.affiliation: Department of Public Health Sciences, University of California, Davis, Sacramento, California, USA.
authors.forename: Nick
authors.identifier: 0000-0002-2999-7284
authors.initials: N
authors.lastname: Anderson
authors.affiliation: Catalyst IT Services, Beaverton, Oregon, USA.
authors.forename: Damon A
authors.identifier: 0000-0002-8095-5653
authors.initials: DA
authors.lastname: Miller
authors.affiliation: Catalyst IT Services, Beaverton, Oregon, USA.
authors.forename: Brett T
authors.initials: BT
authors.lastname: Futral
authors.affiliation: Department of Pediatrics, University of Washington, Seattle, Washington, USA.|Department of Genome Sciences, University of Washington, Seattle, Washington, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Bamshad
mesh_terms: D035843:Biomedical Research; D019295:Computational Biology / Q000379:methods*; D003657:Decision Making; D023281:Genomics; D006801:Humans; D020407:Internet; D008490:Medical Informatics; D033283:Patient Access to Records; D057285:Precision Medicine