title: Angiosarcoma of Anterior Mandibular Gingiva Showing Recurrence - A Case Report with Immunohistochemistry.
abstract: Angiosarcomas of oral cavity and salivary gland represent 1% of all cases reported in the literature and are therefore considered as extremely rare. To the best of our knowledge very few cases of angiosarcomas involving mandibular gingiva have been reported previously. Here, we report a case of angiosarcoma occurring in the gingiva with review of literature on clinical features. A 30-year-old female patient presented with a complaint of a small growing mass in relation to lower front teeth. Intraoral examination revealed a soft sessile growth arising from the labial gingiva in relation to 31 and 41 on the labial aspect extending distally to 32. The lesion was locally excised. Histolopathological analysis showed that the tumour was composed of spindle shaped to polygonal cells with hyperchromatic nuclei, conspicuous nucleoli and intracytoplasmic vacuoles, mitotic figure were also scattered. Immunohistochemical staining revealed that the tumour cells was positive for factor VIII-related antigen, CD31 and CD34. An excisional biopsy showed a diagnosis of angiosarcoma. After two months patient reported back with the same chief complaint. This present case is a 17(th) case report of angiosarcoma arising in anterior mandiblular gingiva.
authors.affiliation: Professor, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital , Raichur, Karnataka, India .
authors.forename: Santosh
authors.initials: S
authors.lastname: Hunasgi
authors.affiliation: Reader, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital , Raichur, Karnataka, India .
authors.forename: Anila
authors.initials: A
authors.lastname: Koneru
authors.affiliation: Professor and Head, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital , Raichur, Karnataka, India .
authors.forename: M
authors.initials: M
authors.lastname: Vanishree
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Pathology, Navodaya Dental College and Hospital , Raichur, Karnataka, India .
authors.forename: Vardendra
authors.initials: V
authors.lastname: Manvikar
keywords: CD31; CD34; Factor VIII-related antigen; Gingiva; Malignant vascular tumour; Mandible