title: Difluoroalkylation/C-H Annulation Cascade Reaction Induced by Visible-Light Photoredox Catalysis.
abstract: We report the first example of difluoroalkylation/C-H annulation cascade reactions of cyclopropyl olefins induced by visible-light photoredox catalysis regioselectively affording partially hydrogenated naphthalenes and quinolines with a variety of difluorinated side chains. The alkylation reagent could be extended to monofluoro and trifluoro reagents, nitrile and malonate. The regioselectivity was investigated by means of density functional theory calculations.
authors.affiliation: Institute of Chemistry and Biomedical Science, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.affiliation: Institute of Chemistry and Biomedical Science, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, China.
authors.forename: Jingzhi
authors.initials: J
authors.lastname: Chen
authors.affiliation: Institute of Chemistry and Biomedical Science, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Jiao
authors.affiliation: Institute of Theoretical and Computational Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, China.
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Wang
authors.affiliation: Institute of Chemistry and Biomedical Science, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Institute of Chemistry and Biomedical Science, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Cheng
authors.affiliation: Institute of Chemistry and Biomedical Science, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, China.|Department of Chemistry and Biochemistry, Texas Tech University , Lubbock, Texas 79409, United States.
authors.forename: Guigen
authors.initials: G
authors.lastname: Li