title: Granular parakeratosis induced by benzalkonium chloride exposure from laundry rinse aids.
abstract: Benzalkonium chloride is a quaternary ammonium cationic detergent present in a number of household products, which can act as a major skin irritant. We present the case of six children who developed granular parakeratosis after exposure to benzalkonium chloride in laundry rinse aids, presenting as a brightly erythematous, tender but minimally pruritic, intertriginous eruption followed by superficial desquamation. The eruptions resolved over 3-4 weeks after cessation of exposure.
authors.affiliation: Department of Dermatology, Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Aaron J
authors.initials: AJ
authors.lastname: Robinson
authors.affiliation: Halbert Dermatology, Hollywood Medical Centre, Perth, Western Australia, Australia.
authors.forename: Rachael S
authors.initials: RS
authors.lastname: Foster
authors.affiliation: Halbert Dermatology, Hollywood Medical Centre, Perth, Western Australia, Australia.|Department of Paediatric Dermatology, Princess Margaret Hospital for Children, Perth, Western Australia, Australia.
authors.forename: Anne R
authors.initials: AR
authors.lastname: Halbert
authors.affiliation: Department of Dermatology, Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Emma
authors.initials: E
authors.lastname: King
authors.affiliation: Department of Dermatology, Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Orchard
mesh_terms: D000293:Adolescent; D001548:Benzalkonium Compounds / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006795:Household Products / Q000009:adverse effects*; D006801:Humans; D007846:Laundering; D008297:Male; D010241:Parakeratosis / Q000139:chemically induced* / Q000473:pathology*
chemical_list: D001548:Benzalkonium Compounds
keywords: benzalkonium chloride; contact dermatitis; granular parakeratosis