title: Microwave Ablation Using Four-Tine Antenna: Effects of Blood Flow Velocity, Vessel Location, and Total Displacement on Porous Hepatic Cancer Tissue.
abstract: This research is concerned with microwave ablation analyses using a 2.45 GHz four-tine (4T) antenna for hepatic cancer tissue. In the study, three-dimensional finite-element models were utilized to examine the tissue temperature distributions during and after MW ablation. A preliminary study was first carried out with regard to the specific absorption rates along the 4T antenna insertion depths and the temperature distributions inside the solid and porous liver models with either 3 cm-in-diameter tumor or 5 cm-in-diameter tumor. Based on the preliminary results, the porous models were further examined for the effect of varying blood flow velocities (0-200 cm/s) with a 1 cm-in-diameter blood vessel next to the antenna and also for the effect of vessel-antenna locations (0, 0.8, and 1.3 cm) with a constant blood flow velocity of 16.7 cm/s. All scenarios were simulated under temperature-controlled mode (90°C). The findings revealed that the blood flow velocity and vessel location influence the ablation effectiveness and that increased blood flow inhibits heat transfer to the vessel wall. At the nearest and farthest vessel-antenna locations (0 and 1.3 cm), approximately 90.3% and 99.55% of the cancer cells were eradicated except for the areas adjacent to the vessel. In addition, total tissue thermal displacement is 5.9 mm which is 6.59% of the total length of the overall model.
authors.affiliation: Department of Electronic Engineering, Faculty of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.
authors.forename: Montree
authors.initials: M
authors.lastname: Chaichanyut
authors.affiliation: Department of Electronic Engineering, Faculty of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.
authors.forename: Supan
authors.identifier: 0000-0002-3938-6057
authors.initials: S
authors.lastname: Tungjitkusolmun
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D001808:Blood Vessels / Q000473:pathology*; D003198:Computer Simulation; D004529:Egg White; D004553:Electric Conductivity; D004867:Equipment Design; D020342:Finite Element Analysis; D006358:Hot Temperature; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008872:Microwaves; D015233:Models, Statistical; D016062:Porosity; D012984:Software; D013552:Swine