title: Serum anti-mullerian hormone: Correlation with the ovarian follicular dynamics in healthy mice.
abstract: To evaluate the relationship between serum anti-Mullerian hormone and follicular dynamics in mice.
  
  
  
  This experimental study was conducted in November, 2014 at the Dow University of Health Sciences, Karachi, and comprised laboratory-bred albino mice. They were sacrifised under anaesthesia and blood was collected via cardiac puncture to assess anti-Mullerian hormone while ovaries were collected for morphometric analyses. SPSS 19 was used for data analysis.
  
  
  
  There were 20 mice with a mean weight of 25±1.89 grams, while weight of the ovaries obtained from these mice was 9.6±0.92mg. The mean serum anti-Mullerian hormone was 29.89±9.7ng/ml. On average, there were 87.8+13.54 primordial follicles, 51.85±8.36 primary, 20.35±5.57 secondary, 11.30±3.38 early antral and 3.05 ± 1.27 late antral follciles (p<0.001; p=0.06)..
  
  
  
  Association of anti-Mullerian hormone with follicle dynamics reflected its role as a true ovarian reserve marker. Its assessment was of great significance in infertile women as well as young patients receiving chemotherapy.
authors.affiliation: Bilogical and Biomedical Sciences, Aga Khan University, Karachi, Pakistan.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Jamil
authors.affiliation: Department of Anatomy, Dow University of Health Sciences, Karachi.
authors.forename: Khalida
authors.initials: K
authors.lastname: Perveen
authors.affiliation: Bilogical and Biomedical Sciences, Aga Khan University, Karachi, Pakistan.
authors.forename: Rabia
authors.initials: R
authors.lastname: Malik
authors.affiliation: Department of Histopathology, Dow University of Health Sciences, Karachi, Pakistan.
authors.forename: Lubna
authors.initials: L
authors.lastname: Avesi
mesh_terms: D000818:Animals; D054304:Anti-Mullerian Hormone / Q000097:blood* / Q000378:metabolism; D015415:Biomarkers; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000097:blood*; D051379:Mice; D006080:Ovarian Follicle / Q000378:metabolism*; D010053:Ovary
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Anti-Mullerian hormone, Ovarian reserve, Follicular dynamics.