title: The Diagnosis and Management of Early Deep Vein Thrombosis.
abstract: The diagnosis and management of an acute DVT is difficult and mistakes are often made. The cost to the National Health Service (NHS) of litigation arising from failure to diagnose and treat DVT early is substantial. Clinical diagnosis alone is often unreliable and a large proportion of DVT occurring in hospital are asymptomatic. In the United Kingdom, clinical scoring systems, D-dimer and ultrasound (US) imaging have all been adopted to aid diagnosis via DVT pathways. These pathways aim to exclude DVT only and often fail to actually address the cause of the symptoms once DVT is eventually cleared.
authors.affiliation: Academic Surgery Unit, University Hospital of South Manchester NHS Trust, 2nd Floor, Education and Research Centre, M23 9LT, Manchester, UK. vivak.hansrani@manchester.ac.uk.
authors.forename: Vivak
authors.initials: V
authors.lastname: Hansrani
authors.affiliation: Academic Surgery Unit, University Hospital of South Manchester NHS Trust, 2nd Floor, Education and Research Centre, M23 9LT, Manchester, UK.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Khanbhai
authors.affiliation: Academic Surgery Unit, University Hospital of South Manchester NHS Trust, 2nd Floor, Education and Research Centre, M23 9LT, Manchester, UK.
authors.forename: Charles
authors.initials: C
authors.lastname: McCollum
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D058070:Asymptomatic Diseases; D015415:Biomarkers / Q000097:blood; D003937:Diagnosis, Differential; D004487:Edema / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D008209:Lymphedema / Q000097:blood / Q000000981:diagnostic imaging* / Q000473:pathology; D010690:Phlebography; D012307:Risk Factors; D017539:Tunica Intima / Q000000981:diagnostic imaging / Q000473:pathology; D018616:Ultrasonography, Doppler, Duplex; D006113:United Kingdom; D014689:Venous Insufficiency / Q000097:blood / Q000000981:diagnostic imaging* / Q000473:pathology; D020246:Venous Thrombosis / Q000097:blood / Q000000981:diagnostic imaging* / Q000473:pathology / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D
keywords: Deep vein thrombosis; Diagnostic pathway; Swollen leg; Venous thromboembolism