title: Systematic evaluation on the effectiveness of conjugated linoleic acid in human health.
abstract: The term CLA (conjugated linoleic acid) corresponds to a mixture of positional and geometric isomers of linoleic acid. Two of these isomers (9c, 11t and 10t, 12c) have biological activity. The milk and dairy products are the most abundant source of conjugated linoleic acid, which refers to a group of positional and geometric isomers of CLA (CLA 18:2 cis-9, cis-12). The following research aims to approach aspects regarding the CLA, as well as its relationship with diseases. Conjugated linoleic acids have been studied for their beneficial effects in the prevention and treatment of many diseases, including obesity, cancer, diabetes, and cardiovascular diseases. Scientific information put together the physiological properties of CLA, which serves as inputs to claim their potential as functional ingredients to be used in the prevention and control of several chronic metabolic disorders.
authors.affiliation: a Departamento de Ciência e Tecnologia de Alimentos Endereço , Endereço, Campus Universitário - Centro de Ciências Rurais Prédio , Santa Maria , Brazil.
authors.forename: Gitane
authors.initials: G
authors.lastname: Fuke
authors.affiliation: a Departamento de Ciência e Tecnologia de Alimentos Endereço , Endereço, Campus Universitário - Centro de Ciências Rurais Prédio , Santa Maria , Brazil.
authors.forename: José Laerte
authors.initials: JL
authors.lastname: Nornberg
mesh_terms: D000818:Animals; D016588:Anticarcinogenic Agents / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use; D001823:Body Composition; D002908:Chronic Disease / Q000517:prevention & control*; D003611:Dairy Products; D019587:Dietary Supplements; D019317:Evidence-Based Medicine; D055951:Functional Food; D006801:Humans; D007333:Insulin Resistance; D044243:Linoleic Acids, Conjugated / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use*; D050356:Lipid Metabolism; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D016588:Anticarcinogenic Agents; D044243:Linoleic Acids, Conjugated
keywords: Conjugated linoleic acid; benefit; dairy; health