title: High Intensity Interval Training Reduces the Levels of Serum Inflammatory Cytokine on Women with Metabolic Syndrome.
abstract: Objectives:This study investigate the effects of a high intensity interval training (HIIT) and 2 weeks of detraining in functional and body composition parameters, lipoproteins, glucose metabolismand inflammation markers in postmenopausal women with metabolic syndrome (MS).Design:17 untrained women with MS underwent a HIIT program for 12 weeks.Methods:The training was performed in treadmills, 3 days per week, with intensity ranging from 70-90% of the maximum heart rate (HRmax) and 2 weeks untrained (inactive). Functional and body composition parameters were evaluated before and after the training, while maximal oxygen uptake, lipoprotein and inflammation markers were analyzed before, after training and also in detraining.Results:The HITT program resulted in changesparameters as glucose, HbA1cand NOx after training. In addition, a reduction in pro-inflammatory interleukins and an increase in IL-10 after the HIIT program were found. However, an increase in plasma levels of lipoprotein was found and body composition parameters remain unaltered.Besides, only 2 weeks of detraining are able to revert the effects on inflammatory parameters afforded by the HIIT program.Conclusions:The HIIT program used here positively affected inflammatory profile and other parameters, as glucose, HbA1cand NOx, on postmenopausal women with MS. Moreover, 2 weeks of detraining can reverse the beneficial effects of HIIT program. Our results point out the necessity to aply acontinuous HITT program, in order maintain the benefits detected, to post menopausal women with MS.
authors.affiliation: Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil.
authors.forename: F M
authors.initials: FM
authors.lastname: Steckling
authors.affiliation: Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil.
authors.forename: J B
authors.initials: JB
authors.lastname: Farinha
authors.affiliation: Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil.
authors.forename: D L D
authors.initials: DL
authors.lastname: Santos
authors.affiliation: Grupo de Investigación en Rendimiento Físico y Salud (IRyS), Escuela de Educación Física, Pontificia Universidad Católica de Valparaiso, Valparaiso, Chile.
authors.forename: G
authors.initials: G
authors.lastname: Bresciani
authors.affiliation: Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil.
authors.forename: J A
authors.initials: JA
authors.lastname: Mortari
authors.affiliation: Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil.
authors.forename: S T
authors.initials: ST
authors.lastname: Stefanello
authors.affiliation: Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil.
authors.forename: A A
authors.initials: AA
authors.lastname: Courtes
authors.affiliation: Programa de Pós-Graduação em Farmacologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Santa Maria, Brazil.
authors.forename: T
authors.initials: T
authors.lastname: Duarte
authors.affiliation: Universidade Luterana do Brazil, Brazil.
authors.forename: M M M F
authors.initials: MM
authors.lastname: Duarte
authors.affiliation: Departamento de Análises Clinicas e Toxicológicas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Brazil.
authors.forename: R N
authors.initials: RN
authors.lastname: Moresco
authors.affiliation: Departamento de Análises Clinicas e Toxicológicas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Brazil.
authors.forename: M S
authors.initials: MS
authors.lastname: Cardoso
authors.affiliation: Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil.
authors.forename: F A A
authors.initials: FA
authors.lastname: Soares
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D016207:Cytokines; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D000072696:High-Intensity Interval Training / Q000379:methods*; D006801:Humans; D007249:Inflammation / Q000097:blood* / Q000628:therapy*; D007378:Interleukins / Q000097:blood*; D024821:Metabolic Syndrome / Q000097:blood* / Q000628:therapy*; D008875:Middle Aged
chemical_list: D001786:Blood Glucose; D016207:Cytokines; D006442:Glycated Hemoglobin; D007378:Interleukins; C517652:hemoglobin A1c protein, human