title: Transfusion medicine in the Formosa Fun Coast water park explosion: The role of combined tissue and blood banking.
abstract: The Formosa Fun Coast explosion, occurring in a recreational water park located in the Northern Taiwan on 27 June 2015, made 499 people burn-injured. For those who had severe burn trauma, surgical intervention and fluid resuscitation were necessary, and potential blood transfusion therapy could be initiated, especially during and after broad escharotomy. Here, we reviewed the literature regarding transfusion medicine and skin grafting as well as described the practicing experience of combined tissue and blood bank in the burn disaster in Taiwan. It was reported that patients who were severely burn-injured could receive multiple blood transfusions during hospitalization. Since the use of skin graft became a mainstay alternative for wound coverage after the early debridement of burn wounds at the beginning of the 20th century, the development of tissue banking program was initiated. In Taiwan, the tissue banking program was started in 2006. And the first combined tissue and blood bank was established in Far Eastern Memorial Hospital in 2010, equipped with the non-sterile, clean and sterile zones distinctly segregated with a unidirectional movement in the sterile area. The sterile zone was a class 10000 clean room equipped with high efficiency particulate air filter (HEPAF) and positive air pressure ventilation. The combined tissue and blood bank has been able to provide the assigned blood products and tissue graft timely and accurately, with the concepts of centralized management. In the future, the training of tissue and blood bank technicians would be continued and fortified, particularly on the regulation and quality control for further bio- and hemovigilance.
authors.affiliation: Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan; Department of Surgery, Far Eastern Memorial Hospital, New Taipei, Taiwan.
authors.forename: Chih-Chun
authors.initials: CC
authors.lastname: Chang
authors.affiliation: Taiwan Blood Services Foundation, Taiwan.
authors.forename: Chin-Chuan
authors.initials: CC
authors.lastname: Yeh
authors.affiliation: Department of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei, Taiwan; School of Medical Laboratory Science and Biotechnology, Taipei Medical University, Taipei, Taiwan; Graduate School of Biotechnology and Bioengineering, Yuan Ze University, Taoyuan, Taiwan(f)Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsinchu, Taiwan; Department of Medical Laboratory Science and Biotechnology, Yuanpei University, Hsinchu, Taiwan. Electronic address: jacpha@mail.femh.org.tw.
authors.forename: Fang-Yeh
authors.initials: FY
authors.lastname: Chu
mesh_terms: D001771:Blood Banks; D002056:Burns / Q000601:surgery*; D054597:Disaster Medicine / Q000379:methods* / Q000458:organization & administration*; D005107:Explosions; D006801:Humans; D000068316:Parks, Recreational; D013624:Taiwan; D014015:Tissue Banks
keywords: Biovigilance; Burn injury; Formosa Fun Coast explosion; Hemovigilance; Tissue bank