title: New Horizons in Pediatric Psychopharmacology.
abstract: Preclinical Research Recent advances in pediatric psychopharmacology have been rather uneven. Increased use of psychotropic drugs among the pediatric population has raised concerns regarding their inappropriate use and safety. While clinical trials have been conducted on various pediatric psychopharmacological drugs, there has been an insignificant amount of importance to innovation in holistic treatment. A rational approach toward elucidating the various challenges would be contingent on the convergence of the development of novel efficacious psychotropic drugs with concrete conceptual frameworks and guidelines fostering enhanced outcomes. A research infrastructure concerning the relevance of the clinician's perspective, combining drugs with alternative therapies, the need for pediatric specific formulations and relevance of these in developing countries provides a basis on which innovative treatment/development can be constructed. The current commentary highlights these comprehensive and targeted treatment guidelines as aspects necessary for building the future of the field. Drug Dev Res 77 : 474-478, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: National Brain Research Center, Manesar, Gurgaon, 122051, India.
authors.forename: Sarah
authors.initials: S
authors.lastname: Khan
authors.affiliation: National Brain Research Center, Manesar, Gurgaon, 122051, India.
authors.forename: Vijaylaxmi
authors.initials: V
authors.lastname: Rathore
authors.affiliation: King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah, 21589, Kingdom of Saudi Arabia.
authors.forename: Shahida
authors.initials: S
authors.lastname: Khan
mesh_terms: D000293:Adolescent; D002648:Child; D055808:Drug Discovery; D006694:Holistic Health; D006801:Humans; D065886:Neurodevelopmental Disorders / Q000188:drug therapy* / Q000628:therapy; D017410:Practice Guidelines as Topic; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D011619:Psychotropic Drugs
keywords: drug development; pediatric psychopharmacology