title: [Vaccine cold chain interruption in a primary care center and economic evaluation].
abstract: OBJECTIVE
  Cold chain control is one of the most important facts to ensure the effectiveness of vaccines links, which requires specific material and human resources for management. The principal objective is to evaluate the interruptions in cold chain of the last 6 years and the possible cost savings that would result in further improvements.
  
  
  METHODS
  A retrospective and descriptive study based on a review of all cold chain interruptions during the last 6 years, at Valdefierro Primary Health Center.
  
  
  RESULTS
  We had 5 interruptions, the maximum temperature reached was 23.1±3.4°C and the longest interruption lasted 25.2±20.7hours. 1611 vaccines were affected and 165 discarded. Total economic loss was 2.098,10 € and 33.611,64 € were savings. The electrical failure was the disruption cause in 5 cases.
  
  
  CONCLUSIONS
  Equipment and staff are essential. The center did some corrective actions, such as minimizing refrigerator time control, minimum stock control, considering population changes, and the center has requested a electrical supply system.
authors.affiliation: Enfermero especialista en Pediatría, Hospital Universitario Miguel Servet, Zaragoza, España. Electronic address: ilarena@salud.aragon.es.
authors.forename: Israel
authors.initials: I
authors.lastname: Larena Fernández
authors.affiliation: Pediatra, Hospital Barbastro, Huesca, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Vara Callau
authors.affiliation: Economista, Departamento de Economía Pública, Facultad de Economía, Universidad de Zaragoza , Zaragoza, España.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Peña Blasco
authors.affiliation: Enfermera especialista en Pediatría, Centro de Salud Valdefierro, Zaragoza, España.
authors.forename: Esther
authors.initials: E
authors.lastname: Atance Melendo
authors.affiliation: Enfermera especialista en Pediatría, Centro de Salud Valdefierro, Zaragoza, España.
authors.forename: Blanca
authors.initials: B
authors.lastname: Gay Gasanz
authors.affiliation: Pediatra, Centro de Salud Valdefierro, Zaragoza, España.
authors.forename: María Jesús Blasco
authors.initials: MJ
authors.lastname: Pérez-Aramendía
mesh_terms: D003362:Cost-Benefit Analysis; D011320:Primary Health Care; D012034:Refrigeration / Q000191:economics* / Q000379:methods* / Q000706:statistics & numerical data; D012189:Retrospective Studies; D014612:Vaccines
chemical_list: D014612:Vaccines
keywords: Drug stability; Economics nursing; Economía de la enfermería; Estabilidad de medicamentos; Gestión de recursos; Refrigeración; Refrigeration; Resources management; Vaccines; Vacunas