title: Mediastinal Mass with Hyper-eosinophilia in a Young Boy -A Diagnostic Dilemma.
abstract: Mediastinal masses in children comprises of a heterogeneous group of tumours. In such cases, biopsy and histological analysis are mandatory for planning of treatment. We have reported an unusual aetiology for a mediastinal mass in a young boy presenting with features of Superior Vena Caval Obstruction (SVCO) who also had marked blood and marrow eosinophilia mimicking Chronic Eosinophilic Leukaemia (CEL). We have also discussed the differential diagnoses of mediastinal tumours with hyper-eosinophilia and possible therapeutic implications.
authors.affiliation: Consultant Medical Oncologist, Assistant Professor in General Medicine, Andaman and Nicobar Island Institute of Medical Sciences , Port Blair, Andaman and Nicobar Islands, India .
authors.forename: Abdul Shahid Poovathum
authors.initials: AS
authors.lastname: Parambil
authors.affiliation: Assistant Professor, Department of Medical Oncology, Regional Cancer Centre , Trivandrum, Kerala, India .
authors.forename: Shruti
authors.initials: S
authors.lastname: Prem
authors.affiliation: Lecturer, Department of Pathology, Regional Cancer Centre , Trivandrum, Kerala, India .
authors.forename: Priya Mary
authors.initials: PM
authors.lastname: Jacob
authors.affiliation: Additional Professor, Department of Pathology, Regional Cancer Centre , Trivandrum, Kerala, India .
authors.forename: Rekha Appukuttan
authors.initials: RA
authors.lastname: Nair
keywords: Chest mass; Histiocytosis; Lymphadenopathy; Mediastinal tumour; Superior Vena Caval Obstruction