title: Predictors of self-reported knee instability among patients with knee osteoarthritis: results of the Amsterdam osteoarthritis cohort.
abstract: The aims of the study were to (i) determine the prevalence and course of self-reported knee instability at 2-year follow-up and (ii) identify factors predictive of retention of self-reported knee instability among patients with established knee osteoarthritis (OA). Among 201 patients from the Amsterdam Osteoarthritis (AMS-OA) cohort, demographic characteristics, self-reported knee instability, muscle strength, proprioception, pain, and physical function were assessed at baseline and at 2 years. Exercise over the past 2 years was assessed by evaluating the medical files. The course of self-reported knee instability was determined in patients reporting instability at baseline. Baseline predictors of self-reported knee instability were determined by uni- and multivariable logistic regression analyses. At baseline, 123 (61 %) patients reported knee instability, and of these, 85 (64 %) patients reported instability 2 years later, while 38 (29 %) reported no instability 2 years later. Poor proprioception and high pain assessed at baseline predicted retention of self-reported knee instability at 2 years among patients with self-reported instability at baseline. Knee instability is highly prevalent among patients with knee osteoarthritis. In patients with self-reported knee instability, the majority retained instability over 2 years. Poor proprioception and high pain predicted retention of self-reported knee instability over time.
authors.affiliation: Amsterdam Rehabilitation Research Center | Reade, P.O. Box 58271, 1040 HG, Amsterdam, the Netherlands. m.vd.esch@reade.nl.
authors.forename: Martin
authors.initials: M
authors.lastname: van der Esch
authors.affiliation: Amsterdam Rehabilitation Research Center | Reade, P.O. Box 58271, 1040 HG, Amsterdam, the Netherlands.|Department of Rehabilitation Medicine, VU University Medical Center, Amsterdam, the Netherlands.|VU University Medical Center, EMGO Institute for Health and Care Research, Amsterdam, the Netherlands.
authors.forename: Marike
authors.initials: M
authors.lastname: van der Leeden
authors.affiliation: Amsterdam Rehabilitation Research Center | Reade, P.O. Box 58271, 1040 HG, Amsterdam, the Netherlands.
authors.forename: Leo D
authors.initials: LD
authors.lastname: Roorda
authors.affiliation: Amsterdam Rheumatology & Immunology Centre, Amsterdam Medical Center, Reade, VU University Medical Center, Amsterdam, the Netherlands.|Jan van Breemen Research Institute, Reade, Amsterdam, the Netherlands.
authors.forename: Willem F
authors.initials: WF
authors.lastname: Lems
authors.affiliation: Department of Rehabilitation Medicine, VU University Medical Center, Amsterdam, the Netherlands.|VU University Medical Center, EMGO Institute for Health and Care Research, Amsterdam, the Netherlands.|VU University Medical Center, Department of Psychiatry, Amsterdam, the Netherlands.
authors.forename: Joost
authors.initials: J
authors.lastname: Dekker
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D018771:Arthralgia / Q000453:epidemiology / Q000503:physiopathology; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007593:Joint Instability / Q000453:epidemiology / Q000503:physiopathology*; D007719:Knee Joint / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D009426:Netherlands; D020370:Osteoarthritis, Knee / Q000453:epidemiology / Q000503:physiopathology*; D010146:Pain / Q000175:diagnosis / Q000453:epidemiology; D059408:Pain Management; D010147:Pain Measurement / Q000379:methods; D015995:Prevalence; D011434:Proprioception; D012044:Regression Analysis; D057566:Self Report; D012720:Severity of Illness Index
keywords: Knee osteoarthritis; Muscle strength; Pain; Proprioception; Self-reported knee instability