title: [CONDYDAV: A multicentre observational study of patients presenting external genital warts in France].
abstract: BACKGROUND
  Since 2007 in France, human papilloma virus (HPV) vaccination has been licensed for use as a vaccine against HPV 6, 11, 16 and 18. The impact on the epidemiology of external genital warts (EGWs) in a large population remains unclear.
  
  
  OBJECTIVE
  To determine epidemiologic and clinical features of patients presenting EGWs in France in the era of HPV vaccination.
  
  
  METHODS
  In this prospective, observational study, we analyzed clinical features and treatments between January 1st, 2012 and March 31, 2012 for patients consulting for EGWs at 15 STI clinics throughout France.
  
  
  RESULTS
  A total of 372 men and 111 women were included; mean age 31.2 years. The women were younger than the men (31.7 and 28.9 years respectively P<0.05). Among the patients, 416 (85.7%) were heterosexual, 13 bisexual and 54 (11.2%) homosexual, including one female. Males reported more sexual partners in the last 12 months (more than 3 partners in 32.6% versus 11.9%, P<0.01). Among the men, 230 had involvement of the penis alone and 46 had involvement of the anus alone. Seventy-six patients had EGWs of the anus, and of these 26 were MSM. In females, 76 had an infection of the vulva alone and 22 co-infection of the vulva and anus. MSM and females were at higher risk than heterosexual males for anal involvement (P<0.0001 and P=0.004, respectively). Three women had been vaccinated: two with Gardasil®and one with Cervarix®. Cryotherapy was the preferred treatment.
  
  
  CONCLUSIONS
  With the advent of HPV vaccination, a global strategy for the prevention and treatment of EGW should be implemented.
authors.affiliation: Département de dermatologie, CIDDIST Tarnier, hôpital Cochin, 89, rue d'Assas, 75006 Paris, France. Electronic address: johan.chanal@hotmail.fr.
authors.forename: J
authors.initials: J
authors.lastname: Chanal
authors.affiliation: Centre des MST, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Fouéré
authors.affiliation: CIDDIST, hôpital de la Croix-Rousse, 103, Grande Rue de la Croix-Rousse, 69004 Lyon, France.
authors.forename: F
authors.initials: F
authors.lastname: Yassir-Oria
authors.affiliation: Centre des IST, hôpital la Grave, 7, place Lange, 31300 Toulouse, France.
authors.forename: N
authors.initials: N
authors.lastname: Spenatto
authors.affiliation: CIDDIST, hôpital Bichat, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Bouscarat
authors.affiliation: Département de dermatologie, hôpital Saint-Eloi, 80, avenue Augustin-Fliche, 34090 Montpellier, France.
authors.forename: E
authors.initials: E
authors.lastname: Picot
authors.affiliation: CDAG/CIDDIST Saint-Adrien, 10, rue Saint-Adrien, 13008 Marseille, France.
authors.forename: P
authors.initials: P
authors.lastname: Martinet
authors.affiliation: DGAS/DPMISP, conseil général 13, 13000 Marseille, France.
authors.forename: C
authors.initials: C
authors.lastname: Vernay-Vaisse
authors.affiliation: Département de dermatologie, hôpital Jean-Mermoz, 3, boulevard Alexandre-Fleming, 25030 Besançon cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Pelletier
authors.affiliation: Département de dermatologie, hôpital Jean-Mermoz, 3, boulevard Alexandre-Fleming, 25030 Besançon cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Courtieu
authors.affiliation: CIDDIST, centre hospitalier de Tourcoing, 155, rue du Président-Coty, 59200 Tourcoing, France.
authors.forename: V
authors.initials: V
authors.lastname: Baclet
authors.affiliation: CIDDIST de Nantes, 44000 Nantes, France.
authors.forename: C
authors.initials: C
authors.lastname: Bernier
authors.affiliation: Conseil départemental des Bouches-du-Rhône, 52, avenue de Saint-Just, 13004 Marseille, France.
authors.forename: D
authors.initials: D
authors.lastname: Aymar-Moulene
authors.affiliation: Département de médecine interne, centre hospitalier régional, 1, rue de la Porte-Madeleine, 45000 Orléans, France.
authors.forename: F
authors.initials: F
authors.lastname: Dupuis-Fourdan
authors.affiliation: CDAG de Nice, 06000 Nice, France.
authors.forename: A
authors.initials: A
authors.lastname: Passeron
authors.affiliation: Département de dermatologie, centre hospitalier Le Mans, 194, avenue Rubillard, 72037 Le Mans, France.
authors.forename: C
authors.initials: C
authors.lastname: Bara-Passot
authors.affiliation: CIDDIST de Nancy, 54000 Nancy, France.
authors.forename: A-L
authors.initials: AL
authors.lastname: Pinault
authors.affiliation: Département de dermatologie, hôpital universitaire, 2, avenue Maréchal-Foch, 29200 Brest, France.
authors.forename: L
authors.initials: L
authors.lastname: Misery
authors.affiliation: Centre des MST, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Janier
authors.affiliation: Département de dermatologie, CIDDIST Tarnier, hôpital Cochin, 89, rue d'Assas, 75006 Paris, France. Electronic address: nicolas.dupin@aphp.fr.
authors.forename: N
authors.initials: N
authors.lastname: Dupin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001004:Anus Diseases / Q000453:epidemiology* / Q000628:therapy; D003218:Condylomata Acuminata / Q000453:epidemiology* / Q000628:therapy; D017679:Cryotherapy; D005260:Female; D005602:France / Q000453:epidemiology; D005831:Genital Diseases, Female / Q000453:epidemiology* / Q000628:therapy; D005832:Genital Diseases, Male / Q000453:epidemiology* / Q000628:therapy; D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012747:Sexual Partners; D019529:Sexuality / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18
keywords: Anogenital warts; Condyloma acuminata; Condylomes; Dispensaires antivénériens; Epidemiology; France; Épidémiologie