title: ACR Appropriateness Criteria® Adjuvant Management of Early-Stage Endometrial Cancer.
abstract: These consensus guidelines on adjuvant radiotherapy for early-stage endometrial cancer were developed from an expert panel convened by the American College of Radiology. The American College of Radiology Appropriateness Criteria® are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method; and Grading of Recommendations Assessment, Development, and Evaluation, or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment. After a review of the published literature, the panel voted on three variants to establish best practices for the utilization of imaging, radiotherapy, and chemotherapy after primary surgery for early-stage endometrial cancer.
authors.forename: Andrew O
authors.initials: AO
authors.lastname: Wahl
authors.forename: David K
authors.initials: DK
authors.lastname: Gaffney
authors.forename: Anuja
authors.initials: A
authors.lastname: Jhingran
authors.forename: Catheryn M
authors.initials: CM
authors.lastname: Yashar
authors.forename: Matthew
authors.initials: M
authors.lastname: Biagioli
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Elshaikh
authors.forename: Shruti
authors.initials: S
authors.lastname: Jolly
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Kidd
authors.forename: Larissa J
authors.initials: LJ
authors.lastname: Lee
authors.forename: Linna
authors.initials: L
authors.lastname: Li
authors.forename: David H
authors.initials: DH
authors.lastname: Moore
authors.forename: Gautam G
authors.initials: GG
authors.lastname: Rao
authors.forename: Ned L
authors.initials: NL
authors.lastname: Williams
authors.forename: William
authors.initials: W
authors.lastname: Small
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D001918:Brachytherapy / Q000009:adverse effects / Q000401:mortality / Q000592:standards*; D017024:Chemotherapy, Adjuvant / Q000592:standards; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D019317:Evidence-Based Medicine / Q000592:standards; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000592:standards; D006801:Humans; D008197:Lymph Node Excision / Q000592:standards; D008495:Medical Oncology / Q000592:standards*; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D011829:Radiation Dosage; D018787:Radiation Oncology / Q000592:standards; D018714:Radiotherapy, Adjuvant / Q000592:standards; D012307:Risk Factors; D016879:Salvage Therapy / Q000592:standards; D000071077:Surgical Oncology / Q000592:standards; D016896:Treatment Outcome