title: Rebuilding motor function of the spinal cord based on functional electrical stimulation.
abstract: Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience. The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology. In this study, the locations of motor function sites in the lumbosacral spinal cord were determined with functional electrical stimulation technology. A three-dimensional map of the lumbosacral spinal cord comprising the relationship between the motor function sites and the corresponding muscle was drawn. Based on the individual experimental parameters and normalized coordinates of the motor function sites, the motor function sites that control a certain muscle were calculated. Phasing pulse sequences were delivered to the determined motor function sites in the spinal cord and hip extension, hip flexion, ankle plantarflexion, and ankle dorsiflexion movements were successfully achieved. The results show that the map of the spinal cord motor function sites was valid. This map can provide guidance for the selection of electrical stimulation sites during the rebuilding of motor function after spinal cord injury.
authors.affiliation: Electronic Information School, Nantong University, Nantong, Jiangsu Province, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.
authors.forename: Xiao-Yan
authors.identifier: 0000-0003-4551-186X
authors.initials: XY
authors.lastname: Shen
authors.affiliation: Electronic Information School, Nantong University, Nantong, Jiangsu Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Du
authors.affiliation: Electronic Information School, Nantong University, Nantong, Jiangsu Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.affiliation: Medical School, Nantong University, Nantong, Jiangsu Province, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Chen
keywords: ankle dorsiflexion; ankle plantarflexion; functional electrical stimulation; hip extension movement; hip flexion movement; lumbosacral spinal cord; motor function sites; movement control; nerve regeneration; neural regeneration; rebuilding motor function; spinal cord; spinal cord injury