title: Electrooptical Analysis of Microbial Cell Suspensions forDetermination of Antibiotic Resistance.
abstract: The effects of ampicillin; kanamycin, chloramphenicol, and tetracycline on electrophysical characteristics of cells of sensitive (ampicillin; kanamycin, chloramphenicol) and resistant (ampicillin; kanamycin, chloramphenicol, tetracycline) Escherichia coli strains were studied. Under the action of antibiotics sensitive and resistant E. coli strains acquire different electro-optical properties. Changes in suspension-orientational spectra, that are observed under the action of ampicillin; kanamycin, chloramphenicol, and tetracycline can be used in determination of antibiotic resistance of the studied bacterial strains. In our opinion, the methods of microbial suspension electro-optical analysis can be used in microbiology, mеdicinе, veterinary, and are an effective tool for solving the problems connected with determination of microbial cell antibiotic resistance.
authors.affiliation: Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, 410049, Russia. guliy_olga@mail.ru.|Vavilov's Saratov State Agrarian University, Saratov, 410012, Russia. guliy_olga@mail.ru.|Saratov Scientific and Research Veterinary Institute Russian Academy of Sciences, Saratov, 410028, Russia. guliy_olga@mail.ru.
authors.forename: Olga I
authors.initials: OI
authors.lastname: Guliy
authors.affiliation: Elosystems GbR, Berlin, Germany.
authors.forename: Victor D
authors.initials: VD
authors.lastname: Bunin
authors.affiliation: Saratov State Medical University, Saratov, 410012, Russia.
authors.forename: Vyacheslav I
authors.initials: VI
authors.lastname: Korzhenevich
authors.affiliation: Vavilov's Saratov State Agrarian University, Saratov, 410012, Russia.|Saratov Scientific and Research Veterinary Institute Russian Academy of Sciences, Saratov, 410028, Russia.
authors.forename: Alexey A
authors.initials: AA
authors.lastname: Volkov
authors.affiliation: Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, 410049, Russia.
authors.forename: Oleg V
authors.initials: OV
authors.lastname: Ignatov
mesh_terms: D000667:Ampicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016764:Cell Polarity / Q000187:drug effects; D002701:Chloramphenicol / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004560:Electricity; D004926:Escherichia coli / Q000187:drug effects* / Q000502:physiology; D007612:Kanamycin / Q000494:pharmacology; D008027:Light; D012542:Scattering, Radiation; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D007612:Kanamycin; D002701:Chloramphenicol; D000667:Ampicillin; D013752:Tetracycline
keywords: Ampicillin; Cells orientational spectrum; Chloramphenicol; Escherichia coli; Kanamycin; Tetracycline