title: An update on applications of nanostructured drug delivery systems in cancer therapy: a review.
abstract: Cancer is a main public health problem that is known as a malignant tumor and out-of-control cell growth, with the potential to assault or spread to other parts of the body. Recently, remarkable efforts have been devoted to develop nanotechnology to improve the delivery of anticancer drug to tumor tissue as minimizing its distribution and toxicity in healthy tissue. Nanotechnology has been extensively used in the advance of new strategies for drug delivery and cancer therapy. Compared to customary drug delivery systems, nano-based drug delivery method has greater potential in different areas, like multiple targeting functionalization, in vivo imaging, extended circulation time, systemic control release, and combined drug delivery. Nanofibers are used for different medical applications such as drug delivery systems.
authors.affiliation: a Department of Clinical Sciences, Tabriz Branch , Islamic Azad University , Tabriz , Iran.|b Young Researchers and Elite Club, Tabriz Branch , Islamic Azad University , Tabriz , Iran.|e Chemical Injuries Research Center , Baqiyatallah University of Medical Sciences , Tehran , Iran.
authors.forename: Seyed Mohsen
authors.initials: SM
authors.lastname: Aberoumandi
authors.affiliation: f Department of Chemistry, Shahrood Branch , Islamic Azad University , Shahrood , Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Mohammadhosseini
authors.affiliation: c Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Elham
authors.initials: E
authors.lastname: Abasi
authors.affiliation: c Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.|i Student Research Committee , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Sepideh
authors.initials: S
authors.lastname: Saghati
authors.affiliation: g Universal Scientific Education and Research Network (USERN) , Tabriz , Iran.|h Department of Basic Sciences , Science and Research Branch, Islamic Azad University , Tehran , Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Nikzamir
authors.affiliation: c Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.|d Biotechnology Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.|g Universal Scientific Education and Research Network (USERN) , Tabriz , Iran.|i Student Research Committee , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Akbarzadeh
authors.affiliation: e Chemical Injuries Research Center , Baqiyatallah University of Medical Sciences , Tehran , Iran.
authors.forename: Yunes
authors.initials: Y
authors.lastname: Panahi
authors.affiliation: c Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.|d Biotechnology Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Soodabeh
authors.initials: S
authors.lastname: Davaran
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000493:pharmacokinetics / Q000627:therapeutic use; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D049329:Nanostructures / Q000737:chemistry / Q000627:therapeutic use; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents
keywords: Nanofiber; cancer therapy; drug delivery; nanotechnology