title: The vital prognosis of elderly adults living in a group home in their mid-eighties.
abstract: The purpose of the present study is to evaluate the vital prognoses of elderly people in their mid-eighties living in a group home (GH) compared to age- and sex-matched outpatient clinic (OPC) in an observational study conducted over 6 years. We investigated the association between mortality and general, cardiac, and nutritional parameters, including eicosapentaenoic acid (EPA) in 54 GH residents (83 ± 8 years old) and 57 OPC attendees (83 ± 5 years old). Kaplan-Meier curves and Cox proportional hazard ratio analyses were used to assess the association between EPA drug administration and mortality in the GH residents and OPC attendees, respectively. The 54 GH residents had higher mortality and poorer nutritional states, as indicated by lower EPA/arachidonic acid values (median 0.20 vs 0.55, p < 0.001), and BMI under the condition without EPA drug administration (1800 mg daily) than did the OPC group. The significant factors that differed between survivors and deceased in the GH residents and OPC attendees were nutritional and cardiac factors. Cox proportional hazard ratio analysis confirmed that a possible determinant of the prognosis was a lower incidence of EPA drug administration and lower hemoglobin in GH. Kaplan-Meier curves and Cox proportional hazard ratio analyses revealed that EPA drug administration significantly reduced the relative mortality by 82 % in the GH residents (p < 0.001) but not in the OPC attendees. The vital prognosis in individuals from GHs was potentially improved by EPA drug administration, which was not the case in the OPC group; however, further prospective studies are needed.
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Kikue
authors.initials: K
authors.lastname: Todoroki
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Yoshimori
authors.initials: Y
authors.lastname: Ikeya
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Sayato
authors.initials: S
authors.lastname: Fukui
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Chiharu
authors.initials: C
authors.lastname: Tanaka
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Kaori
authors.initials: K
authors.lastname: Sekine
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Imazeki
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Shizuma
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Fukuyama
authors.affiliation: Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan. coronary@is.icc.u-tokai.ac.jp.
authors.forename: Hidezo
authors.initials: H
authors.lastname: Mori
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016718:Arachidonic Acid / Q000378:metabolism; D015118:Eicosapentaenoic Acid / Q000378:metabolism; D005260:Female; D016352:Group Homes / Q000706:statistics & numerical data*; D006321:Heart / Q000502:physiology; D006801:Humans; D008297:Male; D009752:Nutritional Status / Q000502:physiology; D011379:Prognosis; D016016:Proportional Hazards Models
chemical_list: D016718:Arachidonic Acid; D015118:Eicosapentaenoic Acid
keywords: Eicosapentaenoic acid; Geriatric medicine; Nutrition; Preventive medicine; Prognosis