title: The ROVT Elan Valved Biplex Conduits for the Reconstruction of the Right Ventricular Outflow Tract.
abstract: The reconstruction of the right ventricular outflow tract (RVOT) system represents a considerable challenge for both manufacturers and surgeons because the patients requiring this type of devices have a very diverse set of anatomical challenges that can lead to complications and subsequent early device failures. We conducted an indepth investigation of a porcine-valve conduit explanted from a patient following an adverse event. A control device was analyzed as a reference. The rapid aging of the porcine valve in the right side of the heart together with major thrombus formation raises several questions. The difficulties encountered with materials used and also the design features of the conduits are once again highlighted. This group of patients continues to increase in number due to success in the surgical outcomes in early childhood. Therefore, there is a greater demand for an appropriate device. However, much work is still needed to achieve this goal, and the best approach to achieving success remains unanswered.
authors.affiliation: Departments of Surgery and Radiology, Faculty of Medicine, Laval University, Axe Medecine Regeneratrice, Centre de Recherche, CHU, Quebec, (QC) Canada.
authors.forename: Robert
authors.initials: R
authors.lastname: Guidoin
authors.affiliation: Key Laboratory of Textile Science and Technology of the Ministry of Education, College of Textile, Donghua University, Shanghai, China.
authors.forename: Yijun
authors.initials: Y
authors.lastname: Fu
authors.affiliation: Department of Vascular Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China; Department of Surgery, Laval University and Division of Regenerative Medicine CHU de Quebec Research Center, Quebec, Quebec City, Canada.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.affiliation: Cardiothoracic Surgery, Leeds General Infirmary Leeds, West Yorkshire, United Kingdom.
authors.forename: Nihal
authors.initials: N
authors.lastname: Weerasena
authors.affiliation: Departments of Surgery and Radiology, Faculty of Medicine, Laval University, Axe Medecine Regeneratrice, Centre de Recherche, CHU, Quebec, (QC) Canada.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Bourget
authors.affiliation: INRS, Energie, materiaux et communications, Varennes (QC) Canada.
authors.forename: Royston
authors.initials: R
authors.lastname: Paynter
authors.affiliation: Departments of Surgery and Radiology, Faculty of Medicine, Laval University, Axe Medecine Regeneratrice, Centre de Recherche, CHU, Quebec, (QC) Canada.
authors.forename: Xinxin
authors.initials: X
authors.lastname: Li
authors.affiliation: Key Laboratory of Textile Science and Technology of Ministry of Education and College of Textiles, Donghua University, Shanghai, PR. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Lin
authors.affiliation: Key Laboratory of Textile Science and Technology of the Ministry of Education, College of Textile, Donghua University, Shanghai, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.affiliation: Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
authors.forename: Boyin
authors.initials: B
authors.lastname: Qin
authors.affiliation: Vascular Surgery, St. Boniface General Hospital and Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
authors.forename: Randolph
authors.initials: R
authors.lastname: Guzman
authors.affiliation: Department of Surgery, Faculty of Medicine, Laval University Quebec, QC, Canada.
authors.forename: Denis
authors.initials: D
authors.lastname: Desaulniers
authors.affiliation: Departments of Surgery and Radiology, Faculty of Medicine, Laval University, Axe Medecine Regeneratrice, Centre de Recherche, CHU, Quebec, (QC) Canada.
authors.forename: Guy
authors.initials: G
authors.lastname: Dionne
authors.affiliation: Departments of Surgery and Radiology, Faculty of Medicine, Laval University, Axe Medecine Regeneratrice, Centre de Recherche, CHU, Quebec, (QC) Canada.
authors.forename: Lucie
authors.initials: L
authors.lastname: Germain
authors.affiliation: Departments of Surgery and Radiology, Faculty of Medicine, Laval University, Axe Medecine Regeneratrice, Centre de Recherche, CHU, Quebec, (QC) Canada.
authors.forename: Ze
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D006330:Heart Defects, Congenital; D006350:Heart Valve Prosthesis; D006352:Heart Ventricles / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D011475:Prosthesis Failure; D019651:Plastic Surgery Procedures; D013552:Swine; D014694:Ventricular Outflow Obstruction