title: [Advances in the research of LuxR family protein in quorum-sensing system of gram-negative bacteria].
abstract: Quorum sensing (QS) is a cell-density-dependent method for information transmission among bacteria, as well as a mechanism for the bacteria to adapt to environment. LuxR family protein plays a key role in gram-negative bacterial QS system as a kind of transcription regulators and participates in a variety of biological behaviors with LuxI protein and signal molecules, such as bioluminescence, biofilm formation, virulence factors production, and so on. The advances in the research of LuxR family protein in QS system of gram-negative bacteria were summarized in this review.
authors.affiliation: Department of Burns and Plastic Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: J
authors.initials: J
authors.lastname: Xiang
mesh_terms: D001419:Bacteria / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006090:Gram-Negative Bacteria; D053038:Quorum Sensing / Q000235:genetics*; D012097:Repressor Proteins; D015534:Trans-Activators; D014157:Transcription Factors
chemical_list: D001426:Bacterial Proteins; C085427:LuxI protein, Bacteria; D012097:Repressor Proteins; D015534:Trans-Activators; D014157:Transcription Factors; C064778:LuxR autoinducer binding proteins