title: The International Takotsubo Registry: Rationale, Design, Objectives, and First Results.
abstract: Takotsubo syndrome (TTS) was first described in Japan in 1990. The clinical presentation is similar to that of acute coronary syndrome (ACS). Cardiac enzymes are commonly elevated. A global initiative was launched and the InterTAK Registry was established to provide a systematic database. The major goals of the International Takotsubo Registry (InterTAK Registry) are to provide a comprehensive clinical characterization on natural history, treatment, and outcomes. We linked a biorepository to identify biomarkers for the diagnosis and prognosis and to investigate the genetic basis as well as disease-related factors. We focus on the rationale, objectives, design, and first results of the InterTAK Registry.
authors.affiliation: Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland. Electronic address: Jelena-Rima.Ghadri@usz.ch.
authors.forename: Jelena-R
authors.initials: JR
authors.lastname: Ghadri
authors.affiliation: Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland.
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Cammann
authors.affiliation: Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland.
authors.forename: Christian
authors.initials: C
authors.lastname: Templin
mesh_terms: D007391:International Cooperation; D007564:Japan; D011379:Prognosis; D012042:Registries; D012107:Research Design; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis* / Q000628:therapy*
keywords: Broken heart syndrome; Cardiomyopathy; Heart failure; International Takotsubo Registry; Takotsubo syndrome