title: Diabetes prevention: Reproductive age women affected by insulin resistance.
abstract: In the United States, 29.1 million people are affected by diabetes, of which 95% have type 2 diabetes. There has been a fivefold increase in type 2 diabetes in the latter half of the 20th century, an increase strongly linked to the obesity epidemic in the United States. In addition, insulin resistance affects 86 million Americans, or more than one-third of the adult population, as manifested by impaired fasting glucose tolerance with random glucose values ranging from ⩾100 to <126 mg/dL. In all, 90% of those affected by impaired fasting glucose tolerance or pre-diabetes are unaware of their metabolic derangement. Although impaired fasting glucose tolerance increases one's risk of developing type 2 diabetes, once identified, application of lifestyle changes by affected individuals may avoid or delay the onset of type 2 diabetes. For reproductive age women who are found to have impaired fasting glucose tolerance, lifestyle changes may be an effective tool to diminish the reproductive health consequences of insulin resistance related diseases.
authors.affiliation: Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Weill Cornell Medical College, New York, NY, USA.
authors.forename: Shadi
authors.initials: S
authors.lastname: Rezai
authors.affiliation: School of Medicine, St. George's University, Grenada, West Indies.
authors.forename: Stephen
authors.initials: S
authors.lastname: LoBue
authors.affiliation: Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Weill Cornell Medical College, New York, NY, USA Cassandra.henderson@nychhc.org.
authors.forename: Cassandra E
authors.initials: CE
authors.lastname: Henderson
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D005215:Fasting / Q000378:metabolism; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007333:Insulin Resistance; D011236:Prediabetic State / Q000503:physiopathology*; D014481:United States; D016387:Women's Health
chemical_list: D001786:Blood Glucose
keywords: Lifestyle changes; diabetes prevention; gestational diabetes; insulin resistance; medical nutrition therapy; preconception counseling; pregnancy; reproductive age women; type 2 diabetes mellitus