title: Trends in incidence and survival analysis in non-melanoma skin cancer from 1994 to 2012 in Girona, Spain: A population-based study.
abstract: BACKGROUND
  We present an epidemiological study focused on Non-melanoma skin cancers (NMSC), including squamous cell carcinoma (SCC), basal cell carcinoma (BCC), Merkel cell carcinoma (MCC), dermatofibrosarcoma protuberans (DFS) and adnexal and skin appendages neoplasm (ASAN), a neoplasm understudied in cancer registries.
  
  
  METHODS
  We analyze trends of incidence and survival of NMSC registered with the Cancer Registry of Girona, Spain.
  
  
  RESULTS
  We found 14389 cases of NMSC, accounting 3,474 SCC, 10729 BCC, 33 MCC, 61 DFSP and 71 ASAN. Incidence increased significantly in SCC and BCC with annual percentage of change of 1.6 and 1.5, respectively, but not in MCC, DFS or ASAN. Five-year relative survival for both sexes was 90.1% in SCC, 99.8% in BCC, 44.2% in MCC, 93.7% in DFS and 84% in ASAN.
  
  
  CONCLUSIONS
  Our study confirms the increasing incidence and good survival of SCC and BCC and enhances knowledge on the epidemiology of the less incidental NMSC.
authors.affiliation: Medical Oncology Department, Catalan Institute of Oncology, Girona, Spain; Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), Girona, Spain; Faculty of Medicine, University of Girona (UdG), Spain. Electronic address: jrubio@iconcologia.net.
authors.forename: J
authors.initials: J
authors.lastname: Rubió-Casadevall
authors.affiliation: Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan Department of Health, Government of Catalonia, Catalan Institute of Oncology, Girona, Spain.
authors.forename: A M
authors.initials: AM
authors.lastname: Hernandez-Pujol
authors.affiliation: Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), Girona, Spain; Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan Department of Health, Government of Catalonia, Catalan Institute of Oncology, Girona, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: Ferreira-Santos
authors.affiliation: Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan Department of Health, Government of Catalonia, Catalan Institute of Oncology, Girona, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Morey-Esteve
authors.affiliation: Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), Girona, Spain; Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan Department of Health, Government of Catalonia, Catalan Institute of Oncology, Girona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Vilardell
authors.affiliation: Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), Girona, Spain; Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan Department of Health, Government of Catalonia, Catalan Institute of Oncology, Girona, Spain; Research Group on Statistics, Econometrics and Health (GRECS), University of Girona (UdG), Spain.
authors.forename: G
authors.initials: G
authors.lastname: Osca-Gelis
authors.affiliation: Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), Girona, Spain; Faculty of Medicine, University of Girona (UdG), Spain; Dermatology Unit, University Hospital Josep Trueta, Catalan Institute of Health, Girona, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Vilar-Coromina
authors.affiliation: Descriptive Epidemiology, Genetics and Cancer Prevention Group, Biomedical Research Institute (IDIBGI), Girona, Spain; Epidemiology Unit and Girona Cancer Registry, Oncology Coordination Plan Department of Health, Government of Catalonia, Catalan Institute of Oncology, Girona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Marcos-Gragera
mesh_terms: D002280:Basal Cell Carcinoma / Q000453:epidemiology; D015266:Carcinoma, Merkel Cell / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000401:mortality; D013030:Spain / Q000453:epidemiology; D016019:Survival Analysis; D013997:Time Factors
keywords: Adnexal and Skin Appendage Neoplasm; Basal cell carcinoma; Cutaneous squamous cell carcinoma; Dermatofibrosarcoma Protuberans; Epidemiology; Incidence; Merkel Cell Carcinoma; Non melanoma skin cancer; Population-based Cancer Registry; Survival