title: Influenza SIRS with Minimal Pneumonitis.
abstract: Although systemic inflammatory response syndrome (SIRS) is a known complication of severe influenza pneumonia, it has been reported very rarely in patients with minimal parenchymal lung disease. We here report a case of severe SIRS, anasarca, and marked vascular phenomena with minimal or no pneumonitis. This case highlights that viruses, including influenza, may cause vascular dysregulation causing SIRS, even without substantial visceral organ involvement.
authors.affiliation: Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine , New Haven, CT , USA.
authors.forename: Shruti
authors.initials: S
authors.lastname: Erramilli
authors.affiliation: Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine , New Haven, CT , USA.
authors.forename: Praveen
authors.initials: P
authors.lastname: Mannam
authors.affiliation: Lawrence and Memorial Hospital , New London, CT , USA.
authors.forename: Constantine A
authors.initials: CA
authors.lastname: Manthous
keywords: ARDS; endothelium; influenza; neuraminidase inhibitors; systemic inflammatory response syndrome