title: [Pulmonary manifestations in collagen vascular diseases].
abstract: OBJECTIVE
  Pulmonary complications are frequent in patients with collagen vascular diseases (CVD). Frequent causes are a direct manifestation of the underlying disease, side effects of specific medications and lung infections.
  
  
  METHODS
  The standard radiological procedure for the work-up of pulmonary pathologies in patients with CVD is multidetector computed tomography (MDCT) with thin-slice high-resolution reconstruction.
  
  
  METHODS
  The accuracy of thin-slice CT for the identification of particular disease patterns is very high. The pattern of usual interstitial pneumonia (UIP) representing the direct pulmonary manifestation of rheumatoid arthritis (RA) can be identified with a sensitivity of 45 % and a specificity of 96 %.
  
  
  RESULTS
  Both direct pulmonary manifestations, drug-induced toxicity and certain infections can have a similar appearance in thin-slice MDCT in various forms of CVD. Knowledge of the patterns and causes contributes to the diagnostic certainty.
  
  
  CONCLUSIONS
  At first diagnosis of a CVD and associated pulmonary symptoms thin-slice MDCT is recommended. Clinical, lung function and imaging follow-up examinations should be performed every 6-12 months depending on the results of the MDCT. In every case the individual CT morphological patterns of pulmonary involvement must be identified. The combination of information on the anamnesis, clinical and imaging results is a prerequisite for an appropriate disease management.
authors.affiliation: Abteilung für Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Thoraxklinik, Universitätsklinikum Heidelberg, Röntgenstr. 1, 69126, Heidelberg, Deutschland. monika.vogel@med.uni-heidelberg.de.|Translational Lung Research Center (TLRC), Universitätsklinikum Heidelberg, Heidelberg, Deutschland. monika.vogel@med.uni-heidelberg.de.
authors.forename: M N A
authors.initials: MN
authors.lastname: Vogel
authors.affiliation: Zentrum für interstitielle und seltene Lungenerkrankungen, Pneumologie und Beatmungsmedizin, Thoraxklinik, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.|Translational Lung Research Center (TLRC), Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Kreuter
authors.affiliation: Abteilung für Diagnostische und Interventionelle Radiologie, Radiologische Klinik, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.|Translational Lung Research Center (TLRC), Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
authors.forename: H-U
authors.initials: HU
authors.lastname: Kauczor
authors.affiliation: Abteilung für Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Thoraxklinik, Universitätsklinikum Heidelberg, Röntgenstr. 1, 69126, Heidelberg, Deutschland.|Abteilung für Diagnostische und Interventionelle Radiologie, Radiologische Klinik, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.|Translational Lung Research Center (TLRC), Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
authors.forename: C-P
authors.initials: CP
authors.lastname: Heußel
mesh_terms: D003095:Collagen Diseases / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging*; D061330:Multidetector Computed Tomography / Q000379:methods*; D013902:Radiography, Thoracic / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014652:Vascular Diseases / Q000000981:diagnostic imaging*
keywords: Causes; Computed tomography; Interstitial lung disease; Patterns; Pulmonary involvement