title: Rhodium/Silver-Cocatalyzed Transannulation of N-Sulfonyl-1,2,3-triazoles with Vinyl Azides: Divergent Synthesis of Pyrroles and 2 H-Pyrazines.
abstract: The first cyclization reaction between vinyl azides and N-sulfonyl-1,2,3-triazoles is reported. A Rh/Ag binary metal catalyst system proved to be necessary for the successful cyclization. By varying the structure of vinyl azides, such reaction allows the divergent synthesis of pyrroles and 2H-pyrazines. The cyclization reactions feature a broad substrate scope, good functional group tolerance, high reaction efficiency, and good to high product yields.
authors.affiliation: Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University, Renmin Str. 5268#, Changchun, 130024, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.affiliation: College of Pharmacy, Qiqihar Medical University, 333 Bukui Street, 161006, Qiqihar, China.
authors.forename: Ge
authors.initials: G
authors.lastname: Sun
authors.affiliation: Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University, Renmin Str. 5268#, Changchun, 130024, China.|State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
authors.forename: Xihe
authors.identifier: http://orcid.org/0000-0002-6694-6742
authors.initials: X
authors.lastname: Bi
mesh_terms: D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D011719:Pyrazines / Q000138:chemical synthesis / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D001386:Azides; D011719:Pyrazines; D011758:Pyrroles; D014230:Triazoles; D012834:Silver; D012238:Rhodium
keywords: pyrazines; pyrroles; rhodium; silver; sulfonyl-1,2,3-triazoles; vinyl azides