title: Reproducibility, interchangeability of measures, time to measure stabilization, and reference values of two tissue oximeters in healthy volunteers.
abstract: This study aimed to compare two tissue oximeters, the INVOS 5100c and the Equanox 7600, in terms of their reproducibility and the interchangeability of their measures. In a randomized order, three measurements were taken at six different sites on both sides of the body in 53 healthy volunteers. Intraclass correlation coefficients (ICC) and within-subject standard deviation (Sw) were calculated for each device. The ICCs were compared using Fisher r-to-z transformation and the Sw were compared using paired-sample t-tests. We found no difference between the reproducibility of the INVOS {ICC=0.92 [95% confidence interval (CI) 0.90 to 0.93]} and Equanox [ICC=0.90 (95% CI 0.88 to 0.93)] in terms of ICCs (p=0.06). However, the Equanox [Sw=1.96 (95% CI 1.91 to 2.02)] showed a better Sw than the INVOS [Sw=2.11 (95% CI 2.05 to 2.17)] (p=0.019). Also, when compared directly to stable condition, the readings produced by the two oximeters varied considerably [ICC 0.43 (95% CI 0.36 to 0.49)]. When taken individually, both tissue oximeters displayed good reproducibility, the Equanox being slightly better than the INVOS in terms of absolute reproducibility. However, when compared, the oximeters showed poor interdevices agreement. Reference values were also described.
authors.affiliation: Université de Montréal, Faculty of Medicine, Department of Family Medicine and Emergency Medicine, 5400 Gouin Ouest, Montréal H4J 1C5, Canada.
authors.forename: Alexis
authors.initials: A
authors.lastname: Cournoyer
authors.affiliation: Université de Montréal, Faculty of Medicine, Department of Anesthesia and Critical Care Division, 5000 Bélanger, Montréal H1T 1C8, Canada.
authors.forename: André
authors.initials: A
authors.lastname: Denault
authors.affiliation: Université de Montréal, Faculty of Nursing, 2375 Côte-Ste-Catherine, Montréal H3T 1A8, Canada.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Cossette
authors.affiliation: Montréal Health Innovations Coordinating Center, 4100 Molson #400, Montréal H1Y 3N1, Canada.
authors.forename: Annik
authors.initials: A
authors.lastname: Fortier
authors.affiliation: Université de Montréal, Faculty of Medicine, Department of Family Medicine and Emergency Medicine, 5400 Gouin Ouest, Montréal H4J 1C5, Canada.
authors.forename: Raoul
authors.initials: R
authors.lastname: Daoust
authors.affiliation: Université de Montréal, Faculty of Medicine, Department of Family Medicine and Emergency Medicine, 5400 Gouin Ouest, Montréal H4J 1C5, Canada.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Iseppon
authors.affiliation: Université de Montréal, Faculty of Medicine, Department of Family Medicine and Emergency Medicine, 5400 Gouin Ouest, Montréal H4J 1C5, Canada.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Chauny
authors.affiliation: Université de Montréal, Faculty of Medicine, Department of Family Medicine and Emergency Medicine, 5400 Gouin Ouest, Montréal H4J 1C5, Canada.
authors.forename: Eric
authors.initials: E
authors.lastname: Notebaert
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry / Q000295:instrumentation / Q000379:methods* / Q000592:standards*; D011446:Prospective Studies; D012016:Reference Values; D012039:Regional Blood Flow / Q000502:physiology; D015203:Reproducibility of Results; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D055815:Young Adult