title: Structural pathology is not related to patient-reported pain and function in patients undergoing meniscal surgery.
abstract: BACKGROUND
  The relationship between meniscal tears and other joint pathologies with patient-reported symptoms is not clear. We investigated associations between structural knee pathologies identified at surgery with preoperative knee pain and function in patients undergoing arthroscopic meniscal surgery.
  
  
  METHODS
  This study included 443 patients from the Knee Arthroscopy Cohort Southern Denmark (KACS), a prospective cohort following patients 18 years or older undergoing arthroscopic meniscal surgery at 4 hospitals between 1 February 2013 and 31 January 2014. Patient-reported outcomes, including the Knee Injury and Osteoarthritis Outcome Score (KOOS), were obtained by online questionnaires prior to surgery. Knee pathology was assessed by the operating surgeons using a modified version of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) classification of meniscal tears questionnaire, supplemented with information extracted from surgery reports. Following hypothesis-driven preselection of candidate variables, backward elimination regressions were performed to investigate associations between patient-reported outcomes and structural knee pathologies.
  
  
  RESULTS
  Regression models only explained a small proportion of the variability in self-reported pain and function (adjusted R2=0.10-0.12) and this association was mainly driven by age, gender and body mass index.
  
  
  CONCLUSIONS
  Specific meniscal pathology and other structural joint pathologies found at meniscal surgery were not associated with preoperative self-reported pain and function in patients with meniscal tears questioning inferences made about a direct relationship between these. Our findings question the role of arthroscopic surgery to address structural pathology as a means to improve patient-reported outcomes in patients having surgery for a meniscal tear.
authors.affiliation: Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.|Department of Orthopaedics, Lillebaelt Hospital, Kolding, Denmark.
authors.forename: Simon Maretti
authors.initials: SM
authors.lastname: Tornbjerg
authors.affiliation: Department of Orthopaedics, Lillebaelt Hospital, Kolding, Denmark.
authors.forename: Nis
authors.initials: N
authors.lastname: Nissen
authors.affiliation: Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Clinical Epidemiology Unit, Lund University, Lund, Sweden.|Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, Massachusetts, USA.
authors.forename: Martin
authors.initials: M
authors.lastname: Englund
authors.affiliation: Department of Orthopaedics and Traumatology, Odense University Hospital, Odense, Denmark.
authors.forename: Uffe
authors.initials: U
authors.lastname: Jørgensen
authors.affiliation: Department of Orthopaedics, Lillebaelt Hospital, Vejle, Denmark.
authors.forename: Jeppe
authors.initials: J
authors.lastname: Schjerning
authors.affiliation: Faculty of Medicine, Department of Clinical Sciences Lund, Orthopaedics, Lund University, Lund, Sweden.
authors.forename: L Stefan
authors.initials: LS
authors.lastname: Lohmander
authors.affiliation: Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
authors.forename: Jonas Bloch
authors.initials: JB
authors.lastname: Thorlund
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000209:etiology*; D001182:Arthroscopy / Q000009:adverse effects; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology; D007718:Knee Injuries / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008592:Menisci, Tibial / Q000601:surgery*; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000473:pathology*; D011446:Prospective Studies; D057566:Self Report; D000070600:Tibial Meniscus Injuries / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Arthroscopy; Knee; Meniscus; Surgery