title: Conclusions.
abstract: The abnormal findings in the pudgy mouse are remarkably similar to those in the severe case of human congenital scoliosis such as seen in the spondylocostal dysplasias. The pudgy mouse is an excellent model to study: (i) how gene mutations translate into three-dimensional structural abnormalities and (ii) which other factors contribute to the final deformities.
authors.affiliation: Laboratory for the Study of Skeletal Disorders, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Frederic
authors.initials: F
authors.lastname: Shapiro