title: Saliviruses-the first knowledge about a newly discovered human picornavirus.
abstract: The salivirus, first discovered in the year 2009, is a member of the large and growing family Picornaviridae. At present, the genus Salivirus contains 1 species Salivirus A and 2 genotypes, Salivirus A1 and Salivirus A2. Salivirus has been identified in humans and chimpanzees and may cause acute gastroenteritis in humans, having been detected in 0% to 8.7% of fecal samples collected from gastroenteritis in different human populations. Salivirus is ubiquitous in wastewater of human origin and river water specimens worldwide and represents a potential indicator human RNA virus for monitoring of environmental samples. This review summarizes the current knowledge on saliviruses including discovery, taxonomy, genome structure, and genetic diversity; covers all aspects of infection including epidemiology, molecular epidemiology, clinical feature, host species, environmental characteristics, and laboratory diagnosis; and gives a summary of possible future perspectives.
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Pécs, Hungary.|Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Reuter
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Pécs, Hungary.|Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Pankovics
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Pécs, Hungary.|Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary.
authors.forename: Ákos
authors.initials: Á
authors.lastname: Boros
mesh_terms: D000818:Animals; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000821:virology; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D002679:Pan troglodytes; D010849:Picornaviridae / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D010850:Picornaviridae Infections / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary* / Q000821:virology*; D018419:Primate Diseases / Q000821:virology; D045483:Rivers / Q000821:virology; D062065:Wastewater / Q000821:virology
chemical_list: D062065:Wastewater
keywords: gastroenteritis; human; picornavirus; salivirus; sewage