title: Indian Herbs for the Treatment of Neurodegenerative Disease.
abstract: Ayurveda, an ancient system of medicine that is indigenous to India, is believed to be the world's oldest comprehensive health-care system and is now one of the most recognized and widely practiced disciplines of alternative medicine in the world. Medicinal herbs have been in use for treating diseases since ancient times in India. Ayurvedic therapies with medicinal herbs and herbomineral products generally provide relief without much adverse effects even after prolonged administration. Neurodegenerative disorders are a major cause of mortality and disability, and increasing life spans represent one of the key challenges of medical research. Ayurvedic medicine describes most neurodegenerative diseases and has defined a number of plants with therapeutic benefits for the treatment of neurodegenerative diseases having antioxidant activities. In this chapter, the role of four important Ayurvedic medicinal plants, viz., Withania somnifera (ashwagandha), Bacopa monnieri (brahmi), Centella asiatica (gotu kola), and Mucuna pruriens (velvet bean), on neurodegenerative diseases are discussed.
authors.affiliation: Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA. Padmanabhan.Mannangatti@vcuhealth.org.
authors.forename: Padmanabhan
authors.initials: P
authors.lastname: Mannangatti
authors.affiliation: Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.
authors.forename: Kamalakkannan Narasimha
authors.initials: KN
authors.lastname: Naidu
mesh_terms: D006801:Humans; D007194:India; D008515:Medicine, Ayurvedic; D019636:Neurodegenerative Diseases / Q000628:therapy*; D008517:Phytotherapy; D010946:Plants, Medicinal
keywords: Ayurveda; Bacopa monnieri; Centella asiatica; Mucuna pruriens; Neurodegenerative disorders; Withania somnifera