title: Residue Analysis of Benzobicyclon in Soil and Sediment Samples by Ultra High-Performance Liquid Chromatography-Tandem Mass Spectrometry.
abstract: A reliable and rapid method was developed to determine benzobicyclon residue in different soil and sediment samples. After extraction via a modified quick, easy, cheap, effective, rugged, and safe method, samples were purified by SPE cleanup with HLB cartridges. Quantitative determination was performed by ultra-HPLC (UPLC)-tandem MS (MS/MS) in electrospray positive ionization and multiple reaction monitoring modes. When samples were fortified at concentrations of 5, 50, and 500 µg/L, recoveries of 80.2 to 114.5% were obtained, with the repeatability (intraday RSDr) and reproducibility (interday RSDR) <14.1 and <21.4%, respectively. The instrumental LODs and LOQs for matrix-matched standards and the method LOQs for sample test were 0.19-1.34 μg/L, 0.64-4.48 μg/L, and 0.32-2.24 μg/kg, respectively. The linear range was 5-1000 μg/L (R2 > 0.99). The established UPLC-MS/MS method was applied in the detection of benzobicyclon in real soil samples, which were collected during the supervised field trial. Results showed that the maximum concentration of benzobicyclon in the soil was 4.87 mg/kg and its degradation half-life (t0.5) was 6.7 days. Generally, the proposed method could be an effective tool for controlling and monitoring the risks posed by benzobicyclon to human health and environmental safety.
authors.affiliation: Zhejiang University, Institute of Pesticide and Environmental Toxicology, Hangzhou 310058, People's Republic of China.
authors.forename: Qianqian
authors.initials: Q
authors.lastname: Sun
authors.affiliation: Zhejiang University, Institute of Pesticide and Environmental Toxicology, Hangzhou 310058, People's Republic of China.
authors.forename: Yihu
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Zhejiang University, Institute of Pesticide and Environmental Toxicology, Hangzhou 310058, People's Republic of China.
authors.forename: Chunxia
authors.initials: C
authors.lastname: Tian
authors.affiliation: Zhejiang University, Institute of Pesticide and Environmental Toxicology, Hangzhou 310058, People's Republic of China.
authors.forename: Wenjun
authors.initials: W
authors.lastname: Gui
authors.affiliation: Zhejiang University, Institute of Pesticide and Environmental Toxicology, Hangzhou 310058, People's Republic of China.
authors.forename: Yirong
authors.initials: Y
authors.lastname: Guo
authors.affiliation: Zhejiang University, Institute of Pesticide and Environmental Toxicology, Hangzhou 310058, People's Republic of China.
authors.forename: Guonian
authors.initials: G
authors.lastname: Zhu
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D019015:Geologic Sediments / Q000737:chemistry*; D010573:Pesticide Residues / Q000032:analysis*; D012987:Soil / Q000737:chemistry*; D013450:Sulfones / Q000032:analysis*; D053719:Tandem Mass Spectrometry
chemical_list: D001643:Bridged Bicyclo Compounds; D010573:Pesticide Residues; D012987:Soil; D013450:Sulfones; C000603422:benzobicyclon