title: Electrochemical Determination of Albendazole at Glassy Carbon Electrode.
abstract: In this article, the electrochemical behavior on a glassy carbon electrode (GCE) was investigated and the electrochemical parameters of albendazole (ALB) were calculated. ALB effectively accumulated on the GCE surface and caused a pair of redox peaks at around 1.095 V and 1.028 V and an oxidation peak at 0.844 V (versus saturated calomel electrode) in 0.2 M phosphate buffer solution (pH 3.0). Under optimized conditions, the anodic peak current was linear to the ALB concentration the range of 1.5 × 10-7M to 4.0 × 10-5M. The regression equation was: Ipa (10-6A) = 0.79 [ALB] (μM) + 0.84 (R2 = 0.982). The detection limit 6.08 × 10-8M was obtained. The proposed method was successfully used to determine ALB content in tablet samples, with satisfactory results.
authors.affiliation: Parappa Channappa Jabin Science College, P.G. Department of Chemistry, Hubballi, India 580031.
authors.forename: Jayant I
authors.initials: JI
authors.lastname: Gowda
authors.affiliation: Parappa Channappa Jabin Science College, P.G. Department of Chemistry, Hubballi, India 580031.
authors.forename: Rahul B
authors.initials: RB
authors.lastname: Kantikar
authors.affiliation: Parappa Channappa Jabin Science College, P.G. Department of Chemistry, Hubballi, India 580031.
authors.forename: Devaraddi G
authors.initials: DG
authors.lastname: Harakuni
authors.affiliation: Parappa Channappa Jabin Science College, P.G. Department of Chemistry, Hubballi, India 580031.
authors.forename: Kirankumar Y
authors.initials: KY
authors.lastname: Jadhav
authors.affiliation: Parappa Channappa Jabin Science College, P.G. Department of Chemistry, Hubballi, India 580031.
authors.forename: Vinay C
authors.initials: VC
authors.lastname: Chanagoudar
authors.affiliation: Karnatak University, Post Graduation Department of Studies in Chemistry, Dharwad, India 580003.
authors.forename: Sharanappa T
authors.initials: ST
authors.lastname: Nandibewoor
mesh_terms: D015766:Albendazole / Q000032:analysis* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D055664:Electrochemical Techniques; D004566:Electrodes
chemical_list: D002244:Carbon; D015766:Albendazole