title: Functional dissection of inhibitory microcircuits in the visual cortex.
abstract: Cerebral cortex contains various types of GABAergic neurons exerting local inhibition. Although the number of GABAergic inhibitory neurons is much smaller than glutamatergic excitatory neurons, they show greater diversity in their morphological and physiological properties. Genetic markers for distinct sub-classes of GABAergic neurons have been identified, and technical advances achieved in the past few decades have brought about a demonstration of a unique function of each sub-class of GABAergic neurons in the cortex. In particular, visual processing in the cortex requires inhibitory function of various GABAergic neurons. Here, we summarize current understandings on the function of inhibitory neurons in the cortex, especially focusing on their roles in visual processing.
authors.affiliation: Department of Biological Sciences, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.
authors.forename: Kwansoo
authors.initials: K
authors.lastname: Kim
authors.affiliation: Department of Biological Sciences, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.
authors.forename: Jae-Hyun
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Biological Sciences, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.
authors.forename: You-Hyang
authors.initials: YH
authors.lastname: Song
authors.affiliation: Department of Biological Sciences, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea. Electronic address: shlee1@kaist.ac.kr.
authors.forename: Seung-Hee
authors.initials: SH
authors.lastname: Lee
mesh_terms: D000200:Action Potentials; D000818:Animals; D059330:GABAergic Neurons / Q000502:physiology; D006801:Humans; D009433:Neural Inhibition; D014793:Visual Cortex / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology
keywords: Cortical microcircuit; GABAergic neurons; Inhibitory neurons; Orientation selectivity; Visual cortex; Visual processing