title: Endovascular repair of abdominal aortic aneurysms.
abstract: Endovascular repair of abdominal aortic aneurysms is an important technique in the vascular surgeon's armamentarium, which has created a seismic shift in the management of aortic pathology over the past two decades. In comparison to traditional open repair, the endovascular approach is associated with significantly improved perioperative morbidity and mortality. The early survival benefit of endovascular abdominal aortic aneurysm repair is sustained up to 3 years postoperatively, but longer-term life expectancy remains poor regardless of operative modality. Nonetheless, most abdominal aortic aneurysms are now repaired using endovascular stent grafts. The technology is not perfect as several postoperative complications, namely endoleak, stent-graft migration, and graft limb thrombosis, can develop and therefore lifelong imaging surveillance is required. In addition, a postoperative inflammatory response has been documented after endovascular repair of aortic aneurysms; the clinical significance of this finding has yet to be determined. Subsequently, the safety and applicability of endovascular stent grafts are likely to improve and expand with the introduction of newer-generation devices and with the simplification of fenestrated systems.
authors.affiliation: Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: darnaoutakis@partners.org.
authors.forename: Dean J
authors.initials: DJ
authors.lastname: Arnaoutakis
authors.affiliation: Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Martin
authors.initials: M
authors.lastname: Zammert
authors.affiliation: St. George's Vascular Institute, University of London, London, England, UK.
authors.forename: Alan
authors.initials: A
authors.lastname: Karthikesalingam
authors.affiliation: Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Belkin
mesh_terms: D000758:Anesthesia / Q000592:standards; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D057510:Endovascular Procedures; D006801:Humans; D015607:Stents / Q000592:standards
keywords: abdominal/surgery; aortic aneurysm; endoleak; endovascular procedure; postoperative complications; treatment outcome