title: Epilepsy surgery for pediatric low-grade gliomas of the cerebral hemispheres: neurosurgical considerations and outcomes.
abstract: BACKGROUND
  Pediatric low-grade tumors are found in roughly 1-3 % of patients with childhood epilepsy; seizures associated with these tumors are often medically refractory and often present a significant morbidity, greater than the presence of the tumor itself.
  
  
  CONCLUSIONS
  The unique morbidity of the seizures often requires an epilepsy surgical approach over a standard oncologic resection to achieve a reduction in morbidity for the child. Multiple quality-of-life studies have shown that unless a patient is seizure-free, they remain disabled throughout their life; the best way to achieve this in our patient population is with a multidisciplinary team approach with treatment goals focusing primarily on the epilepsy.
  
  
  CONCLUSIONS
  In those patients treated with gross total resection, roughly 80 % will have an Engel class I outcome and 90 % will achieve some reduction in seizure frequency with a significant improvement in quality of life.
authors.affiliation: Department of Neurosurgery, University of Tennessee Health Science Center, 847 Monroe Ave., Suite 427, Memphis, TN, 38163, USA. mbrow135@uthsc.edu.
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Brown
authors.affiliation: Department of Neurosurgery, University of Tennessee Health Science Center, 847 Monroe Ave., Suite 427, Memphis, TN, 38163, USA.|Semmes-Murphey Clinic, 6325 Humphreys Blvd, Memphis, TN, 38120, USA.
authors.forename: Frederick A
authors.initials: FA
authors.lastname: Boop
mesh_terms: D001932:Brain Neoplasms / Q000150:complications* / Q000523:psychology; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000209:etiology / Q000473:pathology / Q000601:surgery; D005260:Female; D007839:Functional Laterality / Q000235:genetics / Q000502:physiology*; D005910:Glioma / Q000150:complications* / Q000523:psychology; D006801:Humans; D008297:Male; D059906:Neuroimaging; D019635:Neurosurgical Procedures / Q000379:methods*; D011788:Quality of Life; D016896:Treatment Outcome
keywords: Epilepsy; Pediatric low-grade gliomas; Seizures