title: Retention and Treatment Outcomes of an Undernutrition Program for HIV patients involving Ready-to-Use Therapeutic Food at Gondar University Hospital, Ethiopia: A Cross-Sectional Study.
abstract: BACKGROUND
  Despite global efforts to eradicate poverty and hunger, under-nutrition is still a major health problem, especially in Sub-Saharan Africa, where HIV/AIDS prevalence is also a serious burden.
  
  
  OBJECTIVE
  To assess the retention and outcomes of under-nutrition treatment program in Gondar University Hospital, Ethiopia.
  
  
  METHODS
  A cross-sectional study was conducted in HIV positive children and adults participating in the Ready-to-use Therapeutic Food (RUTF) treatment program at Gondar University Hospital ART clinic for one year from November 2012 to November 2013.
  
  
  METHODS
  Six hundred and thirty six patient records were followed-up for one year. Outcome variables were Mid-Upper Arm Circumference (MUAC) values measured as severe, moderate acute malnutrition, normal after treatment, non-respondent, relapsed and lost to follow-up using the hospital records of HIV positive children and adults eligible for the program.
  
  
  METHODS
  Univariate and multivariate analysis were performed to compute Crude Odds Ratio (COR) and Adjusted Odds Ratio (AOR). Statistical significance was set at p-value<0.05.
  
  
  RESULTS
  Among 636 clients, 44.2% achieved MUAC measures ≥ 125 mm for children and ≥ 21 cm for adults at 4 and 6 months. 70.1% of those were children while 29.9% of the 281 were adults. Moreover, a more positive initial response to ready-to-use therapeutic food was found among children as there was significant increase (p<0.05) in MUAC value after the second month of initiating treatment while adults achieved a significant (p<0.05, p<0.01) in MUAC at the 4(th) and 6(th) month respectively. There was a significant association between age, nutrition status and treatment outcome, while sex, HIV status, education and residency were not associated with treatment outcome.
  
  
  CONCLUSIONS
  Recovery and weight gain rates were below 50%. Defaulter rates were higher than the Sphere standards and recovery was better in children than adults. Integrated RUTF and HIV program and strict follow-up and education or counselling of HIV positive patients should be strengthened.
authors.affiliation: Lecturer, Department of Clinical Pharmacy, University of Gondar-College of Medicine and Health Sciences , Gondar, Ethiopia .
authors.forename: Akshaya Srikanth
authors.initials: AS
authors.lastname: Bhagavathula
authors.affiliation: Lecturer, Department of Clinical Pharmacy, University of Gondar-College of Medicine and Health Sciences , Gondar, Ethiopia .
authors.forename: Henok Getachew
authors.initials: HG
authors.lastname: Tegegn
authors.affiliation: Professor, Faculty of Health, World Health Collaborating Centre, University of Technology , Sydney, Australia .
authors.forename: Angela
authors.initials: A
authors.lastname: Dawson
authors.affiliation: Associate Professor, Department of Clinical Pharmacy, Fathima College of Pharmacy , UAE .
authors.forename: Asim Ahmed
authors.initials: AA
authors.lastname: Elnour
authors.affiliation: Associate Professor, Department of Internal Medicine, College of Medicine and Health Sciences - UAE University , Al Ain, UAE .
authors.forename: Abdulla
authors.initials: A
authors.lastname: Shehab
keywords: Malnutrition; Mid-upper arm circumference; Severe acute malnutrition