title: [A hybrid lesion: Low-grade fibromyxoid sarcoma (LGFMS) and sclerosing epithelioid fibrosarcoma (SEF)].
abstract: We report the case of a 34-year-old woman presenting a 10cm axillary mass diagnosed as hybrid tumor low-grade fibromyxoid sarcoma/sclerosing epithelioid fibrosarcoma. Microbiopsy for morphological and immunohistochemical analyses was associated with molecular analysis (FISH and PCR) to confirm the diagnosis.
authors.affiliation: Service de pathologie, institut Curie, 26, rue d'Ulm, 75248 Paris, France.
authors.forename: Carole
authors.initials: C
authors.lastname: Kesrouani
authors.affiliation: Service de pathologie, hôpital Foch, 40, rue Worth, 92150 Suresnes, France.
authors.forename: Leila
authors.initials: L
authors.lastname: Zemoura
authors.affiliation: Service de pathologie, institut Curie, hôpital René-Huguenin, 26, rue d'Ulm, 75248 Paris, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Trassard
authors.affiliation: Service de pathologie, institut Curie, 26, rue d'Ulm, 75248 Paris, France. Electronic address: marick.lae@curie.fr.
authors.forename: Marick
authors.initials: M
authors.lastname: Laé
mesh_terms: D000328:Adult; D001365:Axilla; D002148:Calmodulin-Binding Proteins / Q000032:analysis; D003131:Combined Modality Therapy; D005260:Female; D005354:Fibrosarcoma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D055264:Mucin-4 / Q000032:analysis; D009363:Neoplasm Proteins / Q000032:analysis; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D034802:RNA-Binding Protein EWS; D034702:RNA-Binding Protein FUS / Q000032:analysis; D016601:RNA-Binding Proteins / Q000032:analysis; D018714:Radiotherapy, Adjuvant; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy
chemical_list: D002148:Calmodulin-Binding Proteins; C500986:EWSR1 protein, human; C000599550:FUS protein, human; C524658:MUC4 protein, human; D055264:Mucin-4; D009363:Neoplasm Proteins; D034802:RNA-Binding Protein EWS; D034702:RNA-Binding Protein FUS; D016601:RNA-Binding Proteins
keywords: EWSR1; FUS; Fibrosarcome épithélioïde sclérosant; Low-grade fibromyxoid sarcoma; MUC4; Sarcome fibromyxoïde de bas grade; Sclerosing epithelioid fibrosarcoma