title: Concise Review: The Use of Adipose-Derived Stromal Vascular Fraction Cells and Platelet Rich Plasma in Regenerative Plastic Surgery.
abstract: Tissue engineering has emerged at the intersection of numerous disciplines to meet a global clinical need for technologies to promote the regeneration of tissues. Recently, many authors have focused their attention on mesenchymal stem/stromal cells (MSCs) for their capacity to differentiate into many cell lineages. The most widely studied cell types are bone marrow mesenchymal stem cells and adipose-derived stem cells (ASCs), which display similar results. Biomaterials, cells, and growth factors are needed to design a regenerative plastic surgery approach in the treatment of organ and tissue defects, but not all tissues are created equal. The aim of this article is to describe the advances in tissue engineering through the use of ASCs, platelet rich plasma, and biomaterials to enable regeneration of damaged complex tissue. Stem Cells 2017;35:117-134.
authors.affiliation: Plastic and Reconstructive Surgery, University of Rome "Tor Vergata", Rome, Italy.|Plastic and Reconstructive Surgery, Catholic University "Our Lady of Good Counsel", Tirane, Albania.
authors.forename: Pietro
authors.initials: P
authors.lastname: Gentile
authors.affiliation: Anatomic Pathology Institute, University of Rome "Tor Vergata", Rome, Italy.
authors.forename: Maria Giovanna
authors.initials: MG
authors.lastname: Scioli
authors.affiliation: Anatomic Pathology Institute, University of Rome "Tor Vergata", Rome, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Bielli
authors.affiliation: Anatomic Pathology Institute, University of Rome "Tor Vergata", Rome, Italy.
authors.forename: Augusto
authors.initials: A
authors.lastname: Orlandi
authors.affiliation: Plastic and Reconstructive Surgery, University of Rome "Tor Vergata", Rome, Italy.
authors.forename: Valerio
authors.initials: V
authors.lastname: Cervelli
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D006801:Humans; D053657:Platelet-Rich Plasma / Q000378:metabolism*; D012038:Regeneration; D017154:Stromal Cells / Q000166:cytology / Q000378:metabolism; D013518:Surgery, Plastic; D023822:Tissue Engineering
keywords: Adipose-derived stem cells; Biomaterials; Platelet rich plasma; Regenerative medicine; Stromal vascular fraction; Tissue engineering