title: Cutaneous sarcoidosis masquerading as chronic cutaneous lupus erythematosus - case report.
abstract: Sarcoidosis is a multisystemic granulomatous disease of unknown origin. Chronic cutaneous lupus erythematosus (CCLE) is an autoimmune disease that is associated with autoantibody production and T-cell dysfunction. Cutaneous manifestations of sarcoidosis may mimic CCLE and vice versa making it difficult to reach a diagnosis clinically.
  
  
  
  We present a case of a 57-year-old woman with long-standing sarcoidosis who presented to clinic with diffuse painful plaques that were very distinct and suggestive of CCLE. She had a family history of both sarcoidosis and CCLE. The patient was immediately started on topical corticosteroids and oral hydroxychloroquine. Skin biopsy and the absence of direct immunofluorescence confirmed a skin manifestation of her previously diagnosed sarcoidosis, despite the clinical morphology favoring classic CCLE.
  
  
  
  Sarcoidosis may have diverse manifestations and may mimic other disease processes. A detailed history along with a low threshold for biopsy is important for determining a diagnosis.
authors.affiliation: SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 46, Brooklyn, NY, 11203, USA.
authors.forename: Marjon
authors.initials: M
authors.lastname: Vatanchi
authors.affiliation: SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 46, Brooklyn, NY, 11203, USA. kaivon.sobhani@downstate.edu.
authors.forename: Kaivon
authors.identifier: 0000-0003-0904-3202
authors.initials: K
authors.lastname: Sobhani
authors.affiliation: Cancer Treatment and Research Center, Mail Code 7876, 7979 Wurzbach Road, San Antonio, TX, 78229-4427, USA.
authors.forename: Valerie T
authors.initials: VT
authors.lastname: Fisher
authors.affiliation: Cancer Treatment and Research Center, Mail Code 7876, 7979 Wurzbach Road, San Antonio, TX, 78229-4427, USA.
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Meffert
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000473:pathology*; D008875:Middle Aged; D012507:Sarcoidosis / Q000473:pathology*
keywords: CCLE; Chronic cutaneous lupus erythematosus; DLE; Discoid lupus; Lupus; Sarcoidosis