title: Nasal Fibrolipomatous Hamartoma, an Idiosyncratic Connective Tissue Malformation in an Infant.
abstract: We describe a congenital mass in the nasopharynx of an infant presenting with dyspnea and feeding difficulties. Magnetic resonance imaging demonstrated 2 separate polypoid nasal cavity masses that were endoscopically resected. Histologically, both lesions were composed of mature adipose tissue with broad fibrous bands and several foci of brown fat. PLAG-1 and HMGA-2 were negative by immunostains. The best diagnosis was a fibrolipomatous hamartoma.
authors.affiliation: a Pathology, Assaf Harofeh Medical Center , Zerifin , Israel.
authors.forename: Gratiana
authors.initials: G
authors.lastname: Hermann
authors.affiliation: b Otolaryngology-Head and Neck Surgery, Assaf Harofeh Medical Center , Zerifin , Israel.
authors.forename: Basel
authors.initials: B
authors.lastname: Jabarin
authors.affiliation: b Otolaryngology-Head and Neck Surgery, Assaf Harofeh Medical Center , Zerifin , Israel.
authors.forename: Tal
authors.initials: T
authors.lastname: Marom
authors.affiliation: c Neonatal Intensive Care Unit, Assaf Harofeh Medical Center , Zerifin , Israel.
authors.forename: Bernard
authors.initials: B
authors.lastname: Barzilay
authors.affiliation: d Pediatric Pulmonology Unit, Assaf Harofeh Medical Center , Zerifin , Israel.
authors.forename: Arnon
authors.initials: A
authors.lastname: Elizur
authors.affiliation: b Otolaryngology-Head and Neck Surgery, Assaf Harofeh Medical Center , Zerifin , Israel.
authors.forename: Ephraim
authors.initials: E
authors.lastname: Eviatar
authors.affiliation: b Otolaryngology-Head and Neck Surgery, Assaf Harofeh Medical Center , Zerifin , Israel.
authors.forename: Jacob
authors.initials: J
authors.lastname: Pitaro
mesh_terms: D017667:Adipocytes / Q000166:cytology; D002001:Adipose Tissue, Brown / Q000378:metabolism; D001921:Brain / Q000000981:diagnostic imaging; D003238:Connective Tissue / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism*; D003937:Diagnosis, Differential; D004724:Endoscopy; D005260:Female; D025743:HMGA2 Protein / Q000378:metabolism*; D006222:Hamartoma / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D016896:Treatment Outcome
chemical_list: D004268:DNA-Binding Proteins; D025743:HMGA2 Protein; C104382:PLAG1 protein, human
keywords: Infant; fibrolipomatous hamartoma; mass; nasal cavity