title: Assessment of clinicopathological features, evaluation of treatment, and prognosis of clear cell and serous papillary endometrial carcinoma.
abstract: We aimed to evaluate and compare the clinical and pathological features, diagnosis, treatment, and prognosis of uterine papillary serous carcinoma (UPSC) and clear-cell carcinoma (CC).
  
  
  
  Thirty-four patients who were operated on for UPSC and CC carcinoma at the İzmir Tepecik Research and Teaching Hospital, between January 1983 and December 2014, were included. Patients were evaluated for the following factors: age, gravidity, parity, preoperative CA-125, tumor size, myometrial and lymphovascular invasion, lymph node tumor metastasis, presence of atypical cells in peritoneal cytology, pathology results, operation types, whether or not they received postoperative adjuvant therapy, prognosis, and death rate.
  
  
  
  The stage of the disease was the main factor affecting disease-free and the overall survival. Cisplatin-based chemotherapy was partially effective in patients with postoperative recurrence, while postoperative adjuvant radiotherapy proved to be more effective in preventing relapse.
  
  
  
  The studied parameters generally were concordant with the literature but, due to the relatively small sample size, more comprehensive and multicenter studies are needed to generate valid results.
authors.affiliation: Tepecik Obstetrics and Gynaecology Training and Research Hospital, Obstetrics and Gynaecology Unit, Izmir, Turkey Erzincan University Medical Faculty, Gynaecology and Obstetrics Department, Erzincan, Turkey. mehmet_kulhan@yahoo.com.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kulhan
authors.forename: Gozde
authors.initials: G
authors.lastname: Kulhan
authors.forename: Umit
authors.initials: U
authors.lastname: Nayki
authors.forename: Cenk
authors.initials: C
authors.lastname: Nayki
authors.forename: Pasa
authors.initials: P
authors.lastname: Ulug
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sipahi
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yildirim
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018394:CA-125 Antigen / Q000097:blood; D002291:Carcinoma, Papillary / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D005260:Female; D020073:Gravidity; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010298:Parity; D018714:Radiotherapy, Adjuvant; D016019:Survival Analysis
chemical_list: D018394:CA-125 Antigen
keywords: clear-cell carcinoma; endometrial tumors; papillary cell carcinoma