title: Two-year Follow-up of Volumetric-modulated Arc Therapy for Treating Internal Mammary Nodes in Locally Advanced Breast Cancer.
abstract: We evaluated dosimetric and clinical results of volumetric-modulated arc therapy (VMAT) treating internal mammary nodes (IMNs) in patients with locally advanced breast cancer.
  
  
  
  Between July 2012 and December 2013, treatment outcomes of 31 patients with stage III breast cancer treated with postoperative radiotherapy including the IMN field using VMAT were analyzed.
  
  
  
  The median follow-up was 25.2 months. VMAT showed good homogeneity and improved conformity. The incidence of lung toxicity of grade 2 or more was 3.2%, and cardiac toxicity was not observed. No patient developed local recurrence.
  
  
  
  VMAT appears safe for the treatment of locally advanced breast cancer including the IMN field.
authors.affiliation: Department of Radiation Oncology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Yi-Jun
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Department of Radiation Oncology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Kyubo
authors.initials: K
authors.lastname: Kim
authors.affiliation: Department of Radiation Oncology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Rena
authors.initials: R
authors.lastname: Lee
authors.affiliation: Department of Radiation Oncology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Jiyoung
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Radiation Oncology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Wonguen
authors.initials: W
authors.lastname: Jung
authors.affiliation: Department of Surgery, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Nam-Sun
authors.initials: NS
authors.lastname: Paik
authors.affiliation: Department of Surgery, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Byung-In
authors.initials: BI
authors.lastname: Moon
authors.affiliation: Department of Surgery, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
authors.forename: Woosung
authors.initials: W
authors.lastname: Lim
authors.affiliation: Department of Radiation Oncology, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea jihae.leee@gmail.com.
authors.forename: Jihae
authors.initials: J
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000528:radiation effects; D042361:Mammary Glands, Human / Q000473:pathology / Q000528:radiation effects; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000532:radiotherapy*; D009367:Neoplasm Staging; D050397:Radiotherapy, Intensity-Modulated
keywords: VMAT; breast cancer; internal mammary nodes