title: Circuits for presaccadic visual remapping.
abstract: Saccadic eye movements rapidly displace the image of the world that is projected onto the retinas. In anticipation of each saccade, many neurons in the visual system shift their receptive fields. This presaccadic change in visual sensitivity, known as remapping, was first documented in the parietal cortex and has been studied in many other brain regions. Remapping requires information about upcoming saccades via corollary discharge. Analyses of neurons in a corollary discharge pathway that targets the frontal eye field (FEF) suggest that remapping may be assembled in the FEF's local microcircuitry. Complementary data from reversible inactivation, neural recording, and modeling studies provide evidence that remapping contributes to transsaccadic continuity of action and perception. Multiple forms of remapping have been reported in the FEF and other brain areas, however, and questions remain about the reasons for these differences. In this review of recent progress, we identify three hypotheses that may help to guide further investigations into the structure and function of circuits for remapping.
authors.affiliation: Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, North Carolina; hri.rao@gmail.com.
authors.forename: Hrishikesh M
authors.initials: HM
authors.lastname: Rao
authors.affiliation: Department of Neurobiology, Duke School of Medicine, Duke University, Durham, North Carolina; and.
authors.forename: J Patrick
authors.identifier: 0000-0001-5696-4667
authors.initials: JP
authors.lastname: Mayo
authors.affiliation: Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, North Carolina.|Department of Neurobiology, Duke School of Medicine, Duke University, Durham, North Carolina; and.|Center for Cognitive Neuroscience, Duke University, Durham, North Carolina.
authors.forename: Marc A
authors.identifier: 0000-0001-5061-763X
authors.initials: MA
authors.lastname: Sommer
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D006801:Humans; D009415:Nerve Net / Q000502:physiology; D010775:Photic Stimulation; D012438:Saccades / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology; D014795:Visual Pathways / Q000502:physiology*
keywords: eye movements; perception; remapping; saccades; vision