title: Drug-eluting stents in superficial femoral artery treatment: could they be the standard of care?
abstract: Endovascular techniques have improved markedly over the past several decades. Plain old balloon angioplasty can only reach patencies around 40% after 1 year. Scaffolding stents have resulted in improved short-term results but encountered limitations for longer-term durability. With the introduction of drug-eluting technologies the process of intimal hyperplasia might be slowed, resulting in improved long-term patency results. At first, limus-eluting technologies were not able to transfer the enthusiasm from the coronaries to the infrainguinal vascular bed. However, the newer generation paclitaxel-eluting technologies perform significantly better in femoropopliteal arteries than their non-eluting or non-coated counterparts. The results of a prospective randomized trial comparing DES versus DCB is eagerly awaited. For the moment there seems, based on the meta-analysis, no difference between the two treatment modalities. Although, we need to keep in mind that DCB perform worse in long calcified lesions.
authors.affiliation: AZ Sint-Blasius Hospital, Dendermonde, Belgium - marc.bosiers@telenet.be.
authors.forename: Marc
authors.initials: M
authors.lastname: Bosiers
authors.forename: Koen
authors.initials: K
authors.lastname: Deloose
authors.forename: Joren
authors.initials: J
authors.lastname: Callaert
authors.forename: Patrick
authors.initials: P
authors.lastname: Peeters
authors.forename: Michel
authors.initials: M
authors.lastname: Bosiers
mesh_terms: D002317:Cardiovascular Agents / Q000008:administration & dosage*; D020099:Coated Materials, Biocompatible / Q000592:standards*; D003251:Constriction, Pathologic; D054855:Drug-Eluting Stents / Q000592:standards*; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation* / Q000592:standards*; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D058729:Peripheral Arterial Disease / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D011474:Prosthesis Design; D012307:Risk Factors; D059039:Standard of Care; D016896:Treatment Outcome; D062666:Vascular Access Devices / Q000592:standards; D014654:Vascular Patency
chemical_list: D002317:Cardiovascular Agents; D020099:Coated Materials, Biocompatible