title: Modifying temporal expectations: Changing cortical responsivity to delayed self-initiated sensations with training.
abstract: The perceptual system makes a specific prediction regarding the timing of impending, self-initiated sensations to facilitate the attenuation of these sensations. The current study used electroencephalography to investigate whether temporal expectations can be modified with training. Participants underwent a button-press-for-tone task and evoked responses to the tones were measured. Fifty participants were randomly assigned to receive repeated exposure (training) to either immediate tones, or tones delayed by 100ms. Pre-training, N1 amplitude to delayed tones was significantly larger compared to immediate tones. However, while training to the immediate tone maintained a significant difference in N1 amplitude between the immediate and delayed tones post-training, this difference was eliminated when trained to the delayed tone. This suggests that participants' neural expectations regarding the anticipated timing of self-generated sensations can be modified with behavioural training. This result has implications for alleviating the subnormal sensory attenuation which has been observed in patients with schizophrenia.
authors.affiliation: School of Psychology, UNSW Australia, Sydney, 2052, Australia. Electronic address: ruth.elijah@unsw.edu.au.
authors.forename: Ruth B
authors.initials: RB
authors.lastname: Elijah
authors.affiliation: School of Psychology, UNSW Australia, Sydney, 2052, Australia.
authors.forename: Mike E
authors.initials: ME
authors.lastname: Le Pelley
authors.affiliation: School of Psychology, UNSW Australia, Sydney, 2052, Australia.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Whitford
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods / Q000523:psychology*; D000293:Adolescent; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D032763:Behavior Control; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D013998:Time Perception / Q000502:physiology*; D055815:Young Adult
keywords: Corollary discharge; Event-Related Potential (ERP); N1-suppression; Sensory attenuation; Temporal expectation