title: Attitudes toward antipsychotic medications as a useful feature in exploring medication non-adherence in schizophrenia.
abstract: To investigate the interest in the attitudes toward antipsychotic medication in exploring medication non-adherence.
  
  
  
  Schizophrenic patients (N=120) completed the Beliefs about Medicines Questionnaire and measures of medication adherence, and clinical outcomes. Comparison between four attitudinal groups and logistic regressions were performed.
  
  
  
  High level of adherence varied significantly between attitudinal groups (Accepting, 70%; Indifferent, 63%; Ambivalent, 50%; Sceptical, 14%; p<0.001). Poor insight and psychic side effects were the most significant predictors of negative beliefs.
  
  
  
  The attitudinal groups approach could facilitate the identification of patients with non-adherence and determine individual targets of interventions to improve negative beliefs.
authors.affiliation: CHU Clermont-Ferrand, University of Auvergne, EA 7280, Clermont-Ferrand, France; Fondation FondaMental, Créteil, France. Electronic address: lsamalin@chu-clermontferrand.fr.
authors.forename: Ludovic
authors.initials: L
authors.lastname: Samalin
authors.affiliation: CHU Clermont-Ferrand, University of Auvergne, EA 7280, Clermont-Ferrand, France.
authors.forename: Ingrid
authors.initials: I
authors.lastname: de Chazeron
authors.affiliation: CHU Clermont-Ferrand, University of Auvergne, EA 7280, Clermont-Ferrand, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Blanc
authors.affiliation: Fondation FondaMental, Créteil, France; University of Paris Est-Créteil, Val-de-Marne, France.
authors.forename: Lore
authors.initials: L
authors.lastname: Brunel
authors.affiliation: Fondation FondaMental, Créteil, France; University of Paris Est-Créteil, Val-de-Marne, France; Pôle de psychiatrie des hôpitaux universitaires H Mondor, INSERM U955, Eq Psychiatrie Translationnelle, Créteil, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Fond
authors.affiliation: CHU Clermont-Ferrand, University of Auvergne, EA 7280, Clermont-Ferrand, France; Fondation FondaMental, Créteil, France.
authors.forename: Pierre-Michel
authors.initials: PM
authors.lastname: Llorca
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001294:Attitude to Health; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D011795:Surveys and Questionnaires
chemical_list: D014150:Antipsychotic Agents
keywords: Adherence; Antipsychotic; Attitudes; Beliefs; Necessity-concerns framework; Schizophrenia