title: Cutaneous manifestations of graft-versus-host disease: role of the dermatologist.
abstract: Graft-versus-host disease (GVHD) is the major complication of hematopoietic stem cell transplantation and is associated with high mortality in severe cases. The skin is one of the major organs affected in both acute and chronic GVHD. This review aims to elucidate the basic characteristics of GVHD, and the role and contribution of dermatologists in the care of patients with this condition.
authors.affiliation: Department of Medicine, Presence Saint Francis Hospital, University of Illinois, Evanston, IL, USA.
authors.forename: Sima
authors.initials: S
authors.lastname: Kavand
authors.affiliation: Department of Dermatology, Mayo Clinic College of Medicine, Rochester, MN, USA.
authors.forename: Julia S
authors.initials: JS
authors.lastname: Lehman
authors.affiliation: Department of Hematology, Mayo Clinic College of Medicine, Rochester, MN, USA.
authors.forename: Shahrukh
authors.initials: S
authors.lastname: Hashmi
authors.affiliation: Department of Dermatology, Mayo Clinic College of Medicine, Rochester, MN, USA.
authors.forename: Lawrence E
authors.initials: LE
authors.lastname: Gibson
authors.affiliation: Department of Dermatology, Mayo Clinic College of Medicine, Rochester, MN, USA.
authors.forename: Rokea A
authors.initials: RA
authors.lastname: El-Azhary
mesh_terms: D000208:Acute Disease; D065095:Calcineurin Inhibitors / Q000627:therapeutic use; D002908:Chronic Disease; D003880:Dermatology; D006086:Graft vs Host Disease / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D011701:PUVA Therapy; D017893:Photopheresis; D010819:Physician's Role; D012307:Risk Factors; D012871:Skin Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D013256:Steroids / Q000627:therapeutic use
chemical_list: D065095:Calcineurin Inhibitors; D016756:Immunoglobulins, Intravenous; D013256:Steroids
keywords: Graft-versus-host disease; hematology; immunology; leukemia; lymphoma; sclerosis; systemic disease; vacuolar interface dermatitis