title: Pd-Catalyzed Carboamination of Alkylidenecyclopropanes: Synthesis of Congested Pyrrolidines and Piperidines.
abstract: The synthesis of densely functionalized N-heterocycles is an ongoing challenge in chemical synthesis. Herein, we report an efficient method for the construction of pyrrolidine and piperidine scaffolds using a palladium-catalyzed carboamination of alkylidenecyclopropanes.
authors.affiliation: Department of Chemistry and Biochemistry, Loyola University Chicago, 1068 West Sheridan Road, Chicago, IL, 60660, USA.
authors.forename: Phillip R
authors.identifier: http://orcid.org/0000-0003-3709-2749
authors.initials: PR
authors.lastname: Lazzara
authors.affiliation: Department of Chemistry and Biochemistry, Loyola University Chicago, 1068 West Sheridan Road, Chicago, IL, 60660, USA.
authors.forename: Keegan P
authors.identifier: http://orcid.org/0000-0001-7780-2800
authors.initials: KP
authors.lastname: Fitzpatrick
authors.affiliation: Department of Chemistry and Biochemistry, Loyola University Chicago, 1068 West Sheridan Road, Chicago, IL, 60660, USA.
authors.forename: Chad C
authors.identifier: http://orcid.org/0000-0002-8427-2358
authors.initials: CC
authors.lastname: Eichman
keywords: aminoarylation; carboamination; homogeneous catalysis; nitrogen heterocycles; palladium catalysis