title: Diagnosis and Management of Deep Vein Thrombosis and Pulmonary Embolism in Pregnancy.
abstract: Pregnancy-associated venous thromboembolism (PAVTE) consists of deep vein thrombosis and pulmonary embolism (PE) occurring during pregnancy or in the postpartum period. This condition is common and is a major source of morbidity in a population which is young and otherwise relatively healthy. Timely diagnosis and treatment are crucial in ensuring satisfactory patient outcomes. Diagnostic strategies for pregnancy-associated PE in particular require careful consideration of maternal and fetal risks. Low-molecular-weight heparins currently form the mainstay of treatment; however, there are uncertainties around optimal dosing of these agents in certain settings (e.g., obesity). This review discusses the diagnosis and suggested treatment of PAVTE.
authors.affiliation: Department of Haematology, Monash Health and Monash University, Clayton, Victoria, Australia.
authors.forename: Ashwini
authors.initials: A
authors.lastname: Bennett
authors.affiliation: Department of Haematology, Monash Health and Monash University, Clayton, Victoria, Australia.
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Chunilal
mesh_terms: D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D011655:Pulmonary Embolism / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D020246:Venous Thrombosis / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D006495:Heparin, Low-Molecular-Weight