title: High serum ion levels in Conserve Plus big femoral head cemented total hip arthroplasty.
abstract: OBJECTIVE
  We report the short-term clinical, radiographic and ion level data of the Conserve Plus metal-on-metal (MoM) big femoral head (BFH) total hip arthroplasty (THA), used with a cemented cobalt-chrome (Co-Cr) Profemur Xm stem and a titanium (Ti) modular neck.
  
  
  RESULTS
  In a consecutive series of 40 hips, survivorship at 3 years was 92.5% with revision for any reason. Average Harris Hip Score was 91.3. There were no implant loosenings. No osteolysis was observed. 5 patients had signs of adverse local tissue reaction (ALTR); their clinical scores were not different from the whole cohort. All but 1 patient had their Co serum ion levels measured. The average Co level was 14,1 µg/l (range 0.9-29.0; median 13.0 µg/l). Clinical scores did not correlate with ion level data. A comparative group of 42 hip resurfacing arthroplasties from the same manufacturer had significantly lower serum Co levels: 1.51 µg/l (range 0.9-4.0; median 0.9 µg/l).
  
  
  CONCLUSIONS
  All patients with the MoM BFH THA design should be followed regularly and should have ion level testing.
authors.affiliation: Department of Orthopaedic Surgery, Jan Yperman Hospital, Ypres - Belgium.
authors.forename: Jan F A
authors.initials: JF
authors.lastname: Somers
authors.affiliation: Lab for Musculoskeletal Sciences and Technology, Department of Surgery and Cancer, Imperial College London, London - UK.
authors.forename: Catherine
authors.initials: C
authors.lastname: Van Der Straeten
authors.affiliation: Laboratory of Clinical Biology, Jan Yperman Hospital, Ypres - Belgium.
authors.forename: Luc
authors.initials: L
authors.lastname: De Coninck
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip; D002857:Chromium; D003035:Cobalt / Q000097:blood*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012086:Reoperation
chemical_list: D002857:Chromium; D003035:Cobalt