title: Graphene-based pipette tip solid-phase extraction with ultra-high performance liquid chromatography and tandem mass spectrometry for the analysis of carbamate pesticide residues in fruit juice.
abstract: Graphene-based pipette tip solid-phase extraction was combined with ultra-high performance liquid chromatography and tandem mass spectrometry for the determination of carbamate pesticide residues in fruit juice samples. Four milligrams of graphene was used as sorbent material to pack a 1000 μL pipette tip for the extraction of pirimicarb, propoxur, isoprocarb, fenobucarb, and diethofencarb from 3 mL of fruit juice sample. The whole extraction process was finished in 12 min, and the volume of eluent used was only 1.5 mL. Under the optimized conditions, good linear relationship (R > 0.999) and lower limits of detection (0.0022-0.033 ng/mL) were achieved. The recoveries at three spiked levels ranged from 80.90 to 124.60% with relative standard deviations less than 4.88%. Compared with commercially available sorbents including propylsulfonic acid silica, graphitized carbon black, and C18, graphene was superior in extraction efficiency. The proposed method is simple, rapid, sensitive, selective, and solvent saving.
authors.affiliation: Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, China.
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Shi
authors.affiliation: Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Li
authors.affiliation: Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Xu
authors.affiliation: Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, China.
authors.forename: Qingru
authors.initials: Q
authors.lastname: Huai
authors.affiliation: Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding, China.
authors.forename: Hongyi
authors.initials: H
authors.lastname: Zhang
mesh_terms: D002219:Carbamates / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D000067030:Fruit and Vegetable Juices / Q000032:analysis*; D006108:Graphite; D010573:Pesticide Residues / Q000302:isolation & purification*; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry
chemical_list: D002219:Carbamates; D010573:Pesticide Residues; D006108:Graphite
keywords: Carbamate pesticides; Fruit juice; Graphene; Pipette tip solid-phase extraction; Ultra-high performance liquid chromatography