title: Interferon β associated nephropathy in a Multiple Sclerosis patient: A case and review.
abstract: BACKGROUND
  Interferon beta (IFN β) subtypes are largely used as immunomodulatory agents in Multiple Sclerosis (MS) treatment. While being generally well tolerated, they can cause various side effects. Adverse effects related to kidney are rarely reported.
  
  
  METHODS
  We report a 32 years old male patient who developed nephrotic syndrome while receiving IFN β for MS. Biopsy showed focal segmental glomerulosclerosis. He went into remisson after cessation of drug and with the aid of angiotensin II antagonists. Here, we report this case and a review of similar cases reported in literature.
  
  
  CONCLUSIONS
  Although it's a rare adverse effect and tend to show good prognosis physicians should pay careful attention to symptoms and findings of nephropathy during follow ups of patients under treatment with these agents.
authors.affiliation: Department of Neurology, Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Tevfik Saglam Cad No:25/2, 34147 Bakirkoy, Istanbul, Turkey. Electronic address: musaozturk2001@yahoo.com.
authors.forename: Musa
authors.initials: M
authors.lastname: Ozturk
authors.affiliation: Department of Neurology, Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Tevfik Saglam Cad No:25/2, 34147 Bakirkoy, Istanbul, Turkey. Electronic address: fbasoglu_crh@hotmail.com.
authors.forename: Fulya
authors.initials: F
authors.lastname: Basoglu
authors.affiliation: Department of Nephrology, Bakirkoy Dr Sadi Konuk Reasaerch and Training Hospital, Tevfik Saglam Street No:11, 34147 Bakirkoy, Istanbul, Turkey. Electronic address: murvetyilmaz@hotmail.com.
authors.forename: Murvet
authors.initials: M
authors.lastname: Yilmaz
authors.affiliation: Department of Pathology, Sisli Hamidiye Etfal Research and Training Hospital, Halaskargazi Boulevard, Etfal Street, 34360 Sisli, Istanbul, Turkey. Electronic address: aaozagari@gmail.com.
authors.forename: Ayse Aysim
authors.initials: AA
authors.lastname: Ozagari
authors.affiliation: Department of Neurology, Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Tevfik Saglam Cad No:25/2, 34147 Bakirkoy, Istanbul, Turkey. Electronic address: baybas@gmail.com.
authors.forename: Sevim
authors.initials: S
authors.lastname: Baybas
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D006801:Humans; D000068556:Interferon beta-1a / Q000009:adverse effects* / Q000627:therapeutic use; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy / Q000473:pathology
chemical_list: D000276:Adjuvants, Immunologic; D000068556:Interferon beta-1a
keywords: Interferon beta; Multiple Sclerosis; Nephrotic syndrome