title: [Interosseous electrostimulation in a model of lengthening with external fixation].
abstract: BACKGROUND
  A fracture repair involves complex cellular processes. However, despite optimal treatment, some fractures heal slowly or do not repair. These complications support the need for innovative therapies. Electromagnetic stimulation is a non-invasive technology that could have a direct impact on many cellular pathways.
  
  
  OBJECTIVE
  To demonstrate the effectiveness of electro-stimulation by alternating current applied during bone elongation to accelerate the consolidation process for 30 days in an animal model.
  
  
  METHODS
  A device with closed circuit and graduated voltage was designed and kept in contact with the external fixator. Group A was elongated without electro-stimulation and group B was electro-stimulated since the beginning of the distraction. Radiographs were taken at 15 and 30 days post-surgical. Haematoxylin and eosin staining and Masson's trichrome stain were performed.
  
  
  RESULTS
  No significant difference were observed in bone density of group A (4.05±3.24, P=0.163). In group B there was a significant difference (61.06±20.17, P=0.03) in bone density. Group A maintained a fibrous tissue repair, with areas of cartilage and bone matrix. Group B had more organised tissue in the stages of bone repair.
  
  
  CONCLUSIONS
  Because there is a significant difference in the growth and callus formation at 15 and 30 days between groups, electro-stimulation could be considered as an adjuvant during bone elongation.
authors.affiliation: Servicio de Ortopedia y Traumatología, Hospital Universitario Dr. José E. González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México. Electronic address: doctorviko@hotmail.com.
authors.forename: Víctor
authors.initials: V
authors.lastname: Peña-Martínez
authors.affiliation: Servicio de Ortopedia y Traumatología, Hospital Universitario Dr. José E. González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
authors.forename: Jorge
authors.initials: J
authors.lastname: Lara-Arias
authors.affiliation: Servicio de Ortopedia y Traumatología, Hospital Universitario Dr. José E. González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
authors.forename: Félix
authors.initials: F
authors.lastname: Vilchez-Cavazos
authors.affiliation: Servicio de Ortopedia y Traumatología, Hospital Universitario Dr. José E. González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Álvarez-Lozano
authors.affiliation: Departamento de Histología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
authors.forename: Roberto
authors.initials: R
authors.lastname: Montes de Oca-Luna
authors.affiliation: Servicio de Ortopedia y Traumatología, Hospital Universitario Dr. José E. González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
authors.forename: Óscar
authors.initials: Ó
authors.lastname: Mendoza-Lemus
mesh_terms: D000818:Animals; D001852:Bone Lengthening / Q000379:methods*; D001842:Bone and Bones; D004285:Dogs; D004599:Electric Stimulation Therapy / Q000379:methods; D016267:External Fixators; D005592:Fracture Fixation; D023421:Models, Animal
keywords: Bone elongation; Electroestimulación interósea; Elongación ósea; External fixation; Fijación externa; Interosseous electro-stimulation