title: Idiopathic neonatal hepatitis or extrahepatic biliary atresia? The role of liver biopsy.
abstract: Cholestasis in early infancy represents a diagnostic dilemma and most of these infants suffer either from extrahepatic biliary atresia or idiopathic neonatal hepatitis. Differentiation between the two conditions may be extremely difficult both clinically and biochemically, and a diagnostic liver biopsy is usually required. We report on a Sudanese infant who presented at the age of 4 weeks with prolonged cholestatic jaundice, abdominal ultrasound was inconclusive, HIDA scan was suggestive of extrahepatic biliary atresia and the diagnosis of idiopathic neonatal hepatitis was only reached by liver biopsy. The infant made full recovery on supportive treatment during a one year follow up period.
authors.affiliation: Department of Paediatrics and Child Health, Faculty of Medicine , University of Khartoum and Soba University Hospital , Sudan.
authors.forename: Abdelmoneim Em
authors.initials: AE
authors.lastname: Kheir
authors.affiliation: Department of Paediatrics , Soba University Hospital, Khartoum , Sudan.
authors.forename: Wisal Ma
authors.initials: WM
authors.lastname: Ahmed
authors.affiliation: Department of Paediatrics , Soba University Hospital, Khartoum , Sudan.
authors.forename: Israa
authors.initials: I
authors.lastname: Gaber
authors.affiliation: Department of Paediatrics , Soba University Hospital, Khartoum , Sudan.
authors.forename: Sara Ma
authors.initials: SM
authors.lastname: Gafer
authors.affiliation: Department of Pathology, Faculty of Medicine, University of Bahri , Sudan.
authors.forename: Badreldin M
authors.initials: BM
authors.lastname: Yousif
keywords: Conjugated hyperbilirubinemia; Giant-cell hepatitis; Idiopathic neonatal hepatitis; Liver biopsy