title: Study on the use of focus harmonic scalpel in thyroidectomies: is it useful also in preserving voice function?
abstract: The aim of this randomized study is to evaluate the real benefits of the FOCUS Harmonic Scalpel in total thyroidectomies compared with conventional ligation, regarding operative time, postoperative blood loss, length of stay and complications. Furthermore, as never seen in other studies, we studied the effects of using the FOCUS during thyroidectomy analyzing the vocal production of patients before and after surgery.
  
  
  
  We enrolled 361 patients who underwent total thyroidectomy from 2008 to 2014. It was a randomized clinical trial in which all the surgical procedures were performed by the same surgeon. Patients were randomized into two groups according to the haemostatic technique: 187 patients were included in a "conventional" group (C) in whom dissection and haemostasis were performed using conventional materials (Vicryl, stitches, V titanium hemostatic clips and monopolar or bipolar electrocautery); 174 patients were included in a group in which the FOCUS was used (F group).
  
  
  
  Our data show that the FOCUS allows a one-third time-saving vs. classic haemostasis. Moreover, the use of the FOCUS would allow reduced traction and reduced manipulation of the thyroid during surgery. Our data demonstrate that the rate of complications in the Focus group might not be significantly reduced. In our series, we noticed that the quantitative acoustic assessment of voice quality show important alterations in several parameters (Shim, Jitt, sPPQ, sAPQ studied with the Multi Dimensional Voice Program evaluation) between the C group and F group.
  
  
  
  The FOCUS Harmonic Scalpel reduces the operative time, post-operative blood loss and length of hospital stay in thyroidectomy. Besides, important vocal alterations after thyroidectomy seem more severe using the conventional technique instead of FOCUS.
authors.affiliation: Department of Sensory Organs, "Sapienza" University of Rome, Azienda Policlinico Umberto I, Rome, Italy. antonio.minni@uniroma1.it.
authors.forename: A
authors.initials: A
authors.lastname: Minni
authors.forename: D
authors.initials: D
authors.lastname: Rosati
authors.forename: C
authors.initials: C
authors.lastname: Cavaliere
authors.forename: A
authors.initials: A
authors.lastname: De Carlo
authors.forename: G
authors.initials: G
authors.lastname: Illuminati
authors.forename: V
authors.initials: V
authors.lastname: Scarano Catanzaro
authors.forename: M
authors.initials: M
authors.lastname: Bodoni
mesh_terms: D000328:Adult; D004564:Electrocoagulation; D005260:Female; D006801:Humans; D008026:Ligation; D008297:Male; D013525:Surgical Instruments; D013961:Thyroid Gland; D013965:Thyroidectomy / Q000379:methods*