title: Neurodynamic treatment did not improve pain and disability at two weeks in patients with chronic nerve-related leg pain: a randomised trial.
abstract: OBJECTIVE
  In people with nerve-related leg pain, does adding neurodynamic treatment to advice to remain active improve leg pain, disability, low back pain, function, global perceived effect and location of symptoms?
  
  
  METHODS
  Randomised trial with concealed allocation and intention-to-treat analysis.
  
  
  METHODS
  Sixty participants with nerve-related leg pain recruited from the community.
  
  
  METHODS
  The experimental group received four sessions of neurodynamic treatment. Both groups received advice to remain active.
  
  
  METHODS
  Leg pain and low back pain (0, none, to 10, worst), Oswestry Disability Index (0, none, to 100, worst), Patient-Specific Functional Scale (0, unable to perform, to 30, able to perform), global perceived effect (-5 to 5) and location of symptoms were measured at 2 and 4 weeks after randomisation. Continuous outcomes were analysed by linear mixed models. Location of symptoms was assessed by relative risk (95% CI).
  
  
  RESULTS
  At 2 weeks, the experimental group did not have significantly greater improvement than the control group in leg pain (MD -1.1, 95% CI -2.3 to 0.1) or disability (MD -3.3, 95% CI -9.6 to 2.9). At 4 weeks, the experimental group experienced a significantly greater reduction in leg pain (MD -2.4, 95% CI -3.6 to -1.2) and low back pain (MD -1.5, 95% CI -2.8 to -0.2). The experimental group also improved significantly more in function at 2 weeks (MD 5.2, 95% CI 2.2 to 8.2) and 4 weeks (MD 4.7, 95% CI 1.7 to 7.8), as well as global perceived effect at 2 weeks (MD 2.5, 95% CI 1.6 to 3.5) and 4 weeks (MD 2.9, 95% CI 1.9 to 3.9). No significant between-group differences occurred in disability at 4 weeks and location of symptoms.
  
  
  CONCLUSIONS
  Adding neurodynamic treatment to advice to remain active did not improve leg pain and disability at 2 weeks.
  
  
  BACKGROUND
  NCT01954199. [Ferreira G, Stieven F, Araujo F, Wiebusch M, Rosa C, Plentz R, et al. (2016) Neurodynamic treatment did not improve pain and disability at two weeks in patients with chronic nerve-related leg pain: a randomised trial.Journal of Physiotherapy62: 197-202].
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Ferreira
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Fábio
authors.initials: F
authors.lastname: Stieven
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Francisco
authors.initials: F
authors.lastname: Araujo
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Matheus
authors.initials: M
authors.lastname: Wiebusch
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Carolina
authors.initials: C
authors.lastname: Rosa
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Plentz
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Silva
mesh_terms: D000328:Adult; D059350:Chronic Pain / Q000503:physiopathology / Q000628:therapy*; D004185:Disability Evaluation; D006233:Persons with Disabilities; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007866:Leg / Q000503:physiopathology*; D017116:Low Back Pain / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000503:physiopathology / Q000628:therapy*; D026741:Physical Therapy Modalities; D016896:Treatment Outcome
keywords: Low back pain; Manual therapy; Neurodynamic treatment; Sciatica; Slump test