title: Symptom Management and Psychosocial Needs of Adults With Acute Myeloid Leukemia During Induction Treatment: A Pilot Study.
abstract: BACKGROUND
  Patients with a new diagnosis of acute myeloid leukemia (AML) are at risk of experiencing a high symptom burden due to the disease and its treatment, which includes a long period of hospitalization.
  
  
  OBJECTIVE
  The aim of this pilot work was to describe the multidimensional symptoms and health-related quality of life experienced by patients with a new diagnosis of AML across induction chemotherapy.
  
  
  METHODS
  A prospective, longitudinal descriptive study design was implemented to evaluate symptoms and health-related quality of life at the time of enrollment through 6 weeks postdiagnosis and identify who might be most at risk of experiencing high symptom burden.
  
  
  RESULTS
  A total of 19 participants were included in this analysis. Moderate to severe levels of distress were present in 25% to 50% of participants, depending on timing in treatment. Females and those with a previous history of a psychological disorder reported higher symptom burden during treatment.
  
  
  CONCLUSIONS
  Our findings indicate that adults with AML experience multiple distressing symptoms during the induction treatment.
  
  
  CONCLUSIONS
  Timely routine multidimensional assessment of symptoms in individuals undergoing induction chemotherapy treatment for AML is critical as they may be experiencing multiple concurrent symptoms. Additional research to advance symptom assessment and amelioration of distressing symptoms to improve health-related quality of life is needed in this unique population.
authors.affiliation: Author Affiliations: School of Nursing (Drs Albrecht and Elswick), and Massey Cancer Center (Dr Albrecht), Virginia Commonwealth University, Richmond; Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pennsylvania (Dr Boyiadzis); School of Nursing, University of Connecticut, Storrs (Dr Starkweather); School of Nursing, University of Pittsburgh, Pennsylvania (Dr Rosenzweig).
authors.forename: Tara A
authors.initials: TA
authors.lastname: Albrecht
authors.forename: Michael
authors.initials: M
authors.lastname: Boyiadzis
authors.forename: R K
authors.initials: RK
authors.lastname: Elswick
authors.forename: Angela
authors.initials: A
authors.lastname: Starkweather
authors.forename: Margaret
authors.initials: M
authors.lastname: Rosenzweig
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000523:psychology* / Q000628:therapy*; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000150:complications / Q000523:psychology; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D011594:Psychometrics / Q000295:instrumentation / Q000379:methods; D011788:Quality of Life / Q000523:psychology*; D057566:Self Report; D011795:Surveys and Questionnaires; D013577:Syndrome