title: Effect of mobile phone radiation on pentylenetetrazole-induced seizure threshold in mice.
abstract: OBJECTIVE
  Scientific interest in potential mobile phone impact on human brain and performance has significantly increased in recent years. The present study was designed to evaluate the effects of mobile phone radiation on seizure threshold in mice.
  
  
  METHODS
  BALB/c male mice were randomly divided into three groups: control, acute, and chronic mobile phone radiation for 30, 60, and 90 min with frequency 900 to 950 MHz and pulse of 217 Hz. The chronic group received 30 days of radiation, while the acute group received only once. The intravenous infusion of pentylenetetrazole (5 mg/ml) was used to induce seizure signs.
  
  
  RESULTS
  Although acute mobile radiation did not change seizure threshold, chronic radiation decreased the clonic and tonic seizure thresholds significantly.
  
  
  CONCLUSIONS
  Our data suggests that the continued and prolonged contact with the mobile phone radiation might increase the risk of seizure attacks and should be limited.
authors.affiliation: Physiology Research Center, Kashan University of Medical Sciences, Kashan, Iran; Department of Neurology, Kashan University of Medical Sciences, Kashan, Iran.
authors.forename: Ebrahim
authors.initials: E
authors.lastname: Kouchaki
authors.affiliation: Department of Neurology, Kashan University of Medical Sciences, Kashan, Iran.
authors.forename: Morteza
authors.initials: M
authors.lastname: Motaghedifard
authors.affiliation: Physiology Research Center, Kashan University of Medical Sciences, Kashan, Iran; Department of Pharmacology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Banafshe
keywords: Mice; Mobile phone radiation; Pentylenetetrazole; Seizure