title: Ultrasonic Elastography Evaluation in Optic Neuritis.
abstract: OBJECTIVE
  In the present study, we attempted to determine whether ultrasonic elastography (USE) evaluation can be used in a diagnosis of optic neuritis (ON).
  
  
  METHODS
  Thirteen patients who each had one normal eye and one eye with a diagnosis of ON were included in the study. Ultrasonography (US) and USE examinations were performed on the affected and non-affected eyes of all participants. Optic nerve and adjacent fat tissue regions at the same depth were selected, and USE measurements were obtained. The optic nerve diameter was measured in both normal and affected eyes.
  
  
  RESULTS
  The mean USE values for the optic nerve were 2.58 ± 0.50 m/s in ON eyes and 1.91 ± 0.39 m/s in normal eyes (p = 0.001). The mean USE values for the optic-nerve adjacent tissue were 2.26 ± 0.45 m/s in ON eyes and 1.77 ± 0.22 m/s in normal eyes (p = 0.001). The mean optic-nerve diameter was 3.80 ± 1.09 mm in ON eyes and 3.28 ± 0.98 mm in normal eyes (p = 0.005).
  
  
  CONCLUSIONS
  USE may be considered an accessible, safe technique for the detection of significant optic-nerve tissue stiffness in ON and may be used an adjunctive tool for confirming this diagnosis.
authors.affiliation: a Departments of Ophthalmology , Yüzüncü Yıl University Medical Faculty , Van , Turkey.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Batur
authors.affiliation: b Departments of Radiology , Yüzüncü Yıl University Medical Faculty , Van , Turkey.
authors.forename: Abdussamet
authors.initials: A
authors.lastname: Batur
authors.affiliation: c Departments of Neurology , Yüzüncü Yıl University Medical Faculty , Van , Turkey.
authors.forename: Vedat
authors.initials: V
authors.lastname: Çilingir
authors.affiliation: a Departments of Ophthalmology , Yüzüncü Yıl University Medical Faculty , Van , Turkey.
authors.forename: Erbil
authors.initials: E
authors.lastname: Seven
authors.affiliation: d Yüzüncü Yıl Gazi University Medical Faculty Departments of Ophthalmology , Ankara , Turkey.
authors.forename: Adnan
authors.initials: A
authors.lastname: Çinal
authors.affiliation: b Departments of Radiology , Yüzüncü Yıl University Medical Faculty , Van , Turkey.
authors.forename: Aydin
authors.initials: A
authors.lastname: Bora
authors.affiliation: a Departments of Ophthalmology , Yüzüncü Yıl University Medical Faculty , Van , Turkey.
authors.forename: Tekin
authors.initials: T
authors.lastname: Yaşar
mesh_terms: D000293:Adolescent; D000328:Adult; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000000981:diagnostic imaging*; D009902:Optic Neuritis / Q000175:diagnosis*; D011446:Prospective Studies; D015203:Reproducibility of Results; D055815:Young Adult
keywords: Optic nerve optic nerve diameter; optic nerve stiffness; ultrasonic elastography; ultrasonography