title: An innovative approach to treating vaginal mesh exposure after abdominal sacral colpopexy: endoscopic resection of mesh and platelet-rich plasma; initial experience in three women.
abstract: OBJECTIVE
  Polypropylene mesh exposure is uncommon after abdominal sacral colpopexy (ASC), but in case of symptomatic vaginal mesh exposure, surgery is needed. When treating it, care must be taken to completely remove the exposed mesh (EM), saving as much vaginal tissue as possible to avoid a subsequent shortened and narrowed vagina. In this video, we present a minimally invasive technique for treating EM after ASC using endoscopic mesh resection and autologous platelet-rich plasma (PRP) technology.
  
  
  METHODS
  Three women were referred to our outpatient clinic for vaginal vault mesh exposure after laparoscopic ASC with concomitant hysterectomy. All women underwent endoscopic bipolar PlasmaKinetic resection (BPR) of EM, and PRP gel was delivered in the surgical site to cover the gap left by the resection.
  
  
  RESULTS
  Mean operative time was 39.6 min. Surgery was uneventful in all cases. All women recovered sexual function, and nobody experienced relapsed pelvic organ prolapse at 1-year follow-up.
  
  
  CONCLUSIONS
  Our preliminary results show that BPR and PRP are safe, effective, and feasible for treating vaginal mesh exposure with conservation of anatomy and sexual function.
authors.affiliation: Department of Life Health & Environmental Sciences, University of L'Aquila, Urology Unit, "Giuseppe Mazzini" Hospital, Piazza Italia, 64100, Teramo, Italy. danielecastellani@tiscali.it.
authors.forename: Daniele
authors.initials: D
authors.lastname: Castellani
authors.affiliation: Department of Life Health & Environmental Sciences, University of L'Aquila, Urology Unit, "Giuseppe Mazzini" Hospital, Piazza Italia, 64100, Teramo, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Valloni
authors.affiliation: Department of Life Health & Environmental Sciences, University of L'Aquila, Urology Unit, "Giuseppe Mazzini" Hospital, Piazza Italia, 64100, Teramo, Italy.
authors.forename: Angela
authors.initials: A
authors.lastname: Piccirilli
authors.affiliation: Department of Life Health & Environmental Sciences, University of L'Aquila, Urology Unit, "Giuseppe Mazzini" Hospital, Piazza Italia, 64100, Teramo, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Paradiso Galatioto
authors.affiliation: Department of Life Health & Environmental Sciences, University of L'Aquila, Urology Unit, "Giuseppe Mazzini" Hospital, Piazza Italia, 64100, Teramo, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Vicentini
mesh_terms: D000282:Administration, Intravaginal; D000368:Aged; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D053657:Platelet-Rich Plasma; D011126:Polypropylenes; D013526:Surgical Mesh / Q000009:adverse effects*; D014621:Vagina / Q000601:surgery*
chemical_list: D011126:Polypropylenes
keywords: Mesh complication; Natural orifice endoscopic surgery; PlasmaKinetic energy; Platelet-rich gel; Platelet-rich plasma; Sacrocolpopexy