title: Epidermotropic progression of melanoma during therapy with vemurafenib and trametinib.
authors.affiliation: Department of Oncology, Anatomic Pathology Unit, Geatano Rummo General Hospital, Benevento, Italy. Electronic address: gerardo.ferrara@libero.it.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Ferrara
authors.affiliation: Department of Anatomic Pathology, Santa Maria degli Angeli Hospital, Pordenone, Italy.
authors.forename: Veronica
authors.initials: V
authors.lastname: Cacitti
authors.affiliation: Laboratory of Clinical Research and Advanced Diagnostics, Istituto di Ricovero e Cura a Carattere Scientifico - Centro di Riferimento Oncologico della Basilicata (IRCCS - CROB), Rionero in Vulture, Italy.
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Improta
authors.affiliation: Department of Medical Oncology, Santa Maria degli Angeli Hospital, Pordenone, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Lo Re
authors.affiliation: Department of Dermatology, Santa Maria degli Angeli Hospital, Pordenone, Italy.
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Corradin
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D046169:Dermoscopy; D018450:Disease Progression; D057915:Drug Substitution; D004817:Epidermis / Q000473:pathology; D005355:Fibrosis; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage; D007211:Indoles / Q000008:administration & dosage; D008297:Male; D008545:Melanoma / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008548:Melanosis / Q000209:etiology; D020125:Mutation, Missense; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors / Q000235:genetics; D010091:Oximes / Q000008:administration & dosage; D047428:Protein Kinase Inhibitors / Q000008:administration & dosage; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors / Q000235:genetics; D011728:Pyridones / Q000008:administration & dosage; D011744:Pyrimidinones / Q000008:administration & dosage; D012074:Remission Induction; D012878:Skin Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D013379:Substrate Specificity; D013449:Sulfonamides / Q000008:administration & dosage; D000077484:Vemurafenib; D000096142:Cutaneous Malignant Melanoma
chemical_list: D007093:Imidazoles; D007211:Indoles; D009363:Neoplasm Proteins; D010091:Oximes; D047428:Protein Kinase Inhibitors; D011728:Pyridones; D011744:Pyrimidinones; D013449:Sulfonamides; D000077484:Vemurafenib; C560077:trametinib; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf; C561627:dabrafenib
keywords: dermoscopic digital monitoring; dermoscopy; histopathology; melanoma; trametinib; vemurafenib