title: Copper Bioaccumulation and Depuration in Common Carp (Cyprinus carpio) Following Co-exposure to TiO2and CuO Nanoparticles.
abstract: Metal oxide nanoparticles (NPs), such as TiO2and CuO, are widely applied in an increasing number of products and applications, and therefore their release to the aquatic ecosystems is unavoidable. However, little is known about joint toxicity of different NPs on tissues of aquatic organisms, such as fish. This study was conducted to assess the uptake and depuration of Cu following exposure to CuO NPs in the presence of TiO2NPs in the liver, intestine, muscle, and gill of common carp, Cyprinus carpio. Carps with a mean total length of 23 ± 1.5 cm and mean weight of 13 ± 1.3 g were divided into 6 groups of 15 each (1 control group) and exposed to TiO2NPs, CuO NPs, and a mixture of TiO2and CuO NPs for periods of 20 days for uptake and 10 days for depuration. The determination of total Cu concentration was carried out by an ICP-OES. The order of Cu uptake in different tissues of the carps was liver > gill > muscle > intestine in both levels of CuO NPs alone; results showed that the total Cu concentrations in the presence of TiO2nanoparticles were increased and were in the sequence of liver > gill > intestine > muscle. In depuration period, Cu concentrations were decreased in all treatments in the sequence of gill > intestine > muscle > liver. Uptake of Cu in different tissues of common carp increased with increasing concentration and time and was tissues- and time-dependent. In conclusion, this study suggested that the uptake of Cu in the tissues of common carp increased in the joint presence of TiO2NPs.
authors.affiliation: Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.
authors.forename: Borhan
authors.initials: B
authors.lastname: Mansouri
authors.affiliation: Environmental Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
authors.forename: Afshin
authors.initials: A
authors.lastname: Maleki
authors.affiliation: Department of Fisheries, Faculty of Natural Resources, University of Kurdistan, Sanandaj, Iran.
authors.forename: Seyed Ali
authors.initials: SA
authors.lastname: Johari
authors.affiliation: Environmental Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Shahmoradi
authors.affiliation: Environmental Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
authors.forename: Ebrahim
authors.initials: E
authors.lastname: Mohammadi
authors.affiliation: Environmental Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
authors.forename: Siros
authors.initials: S
authors.lastname: Shahsavari
authors.affiliation: Environmental Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran. davaribehroz@gmail.com.|Department of Medical Entomology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. davaribehroz@gmail.com.
authors.forename: Behroz
authors.initials: B
authors.lastname: Davari
mesh_terms: D000818:Animals; D002347:Carps / Q000378:metabolism*; D003300:Copper / Q000378:metabolism* / Q000633:toxicity; D053758:Nanoparticles / Q000633:toxicity*; D014025:Titanium / Q000633:toxicity*; D018675:Toxicity Tests; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D014874:Water Pollutants, Chemical; C009495:titanium dioxide; D003300:Copper; D014025:Titanium; C030973:cupric oxide