title: Current advances in electrospun gelatin-based scaffolds for tissue engineering applications.
abstract: The development of biomimetic highly-porous scaffolds is essential for successful tissue engineering. Electrospun nanofibers are highly versatile platforms for a broad range of applications in different research areas. In the biomedical field, micro/nanoscale fibrous structures have gained great interest for wound dressings, drug delivery systems, soft and hard-tissue engineering scaffolds, enzyme immobilization, among other healthcare applications. In this mini-review, electrospun gelatin-based scaffolds for a variety of tissue engineering applications, such as bone, cartilage, skin, nerve, and ocular and vascular tissue engineering, are reviewed and discussed. Gelatin blends with natural or synthetic polymers exhibit physicochemical, biomechanical, and biocompatibility properties very attractive for scaffolding. Current advances and challenges on this research field are presented.
authors.affiliation: Instituto de Investigaciones en Ciencia y Tecnología de Materiales, INTEMA (UNMdP-CONICET), Av. Juan B. Justo 4302, B7608FDQ Mar del Plata, Argentina.
authors.forename: Ana A
authors.initials: AA
authors.lastname: Aldana
authors.affiliation: Instituto de Investigaciones en Ciencia y Tecnología de Materiales, INTEMA (UNMdP-CONICET), Av. Juan B. Justo 4302, B7608FDQ Mar del Plata, Argentina. Electronic address: gabraham@fi.mdp.edu.ar.
authors.forename: Gustavo A
authors.initials: GA
authors.lastname: Abraham
mesh_terms: D005780:Gelatin / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry; D011108:Polymers; D023822:Tissue Engineering; D054457:Tissue Scaffolds
chemical_list: D011108:Polymers; D005780:Gelatin
keywords: Biopolymers; Electrospun scaffolds; Gelatin; Tissue engineering