title: Secondary Metabolites from Acremonium Fungi: Diverse Structures and Bioactivities.
abstract: BACKGROUND
  Acremonium fungi have been isolated from various sources, such as soil, plants, and marine organisms.
  
  
  METHODS
  The species in Acremonium have been proved to be rich sources of novel and bioactive secondary metabolites. Up to now, 356 metabolites belonging to steroids (6 compounds), terpenoids (86), meroterpenoids (66), polyketides (89), alkaloids (28), peptides (75), and miscellaneous types (6) have been isolated from Acremonium fungi. These metabolites displayed a wide range of biological activities including antimicrobial, cytotoxic, antitumor, immunosuppressive, antioxidant, antiinflammatory, antimalarial, phytotoxic, tremorgenic, antiviral, neuritogenic, insecticidal and enzymesinhibiting activities.
  
  
  CONCLUSIONS
  This review highlights the structures and bioactivities of the secondary metabolites from Acremonium fungi reported until July 2016.
authors.forename: Jin
authors.initials: J
authors.lastname: Tian
authors.affiliation: Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, China.
authors.forename: Daowan
authors.initials: D
authors.lastname: Lai
authors.affiliation: Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, India.
authors.forename: Ligang
authors.initials: L
authors.lastname: Zhou
mesh_terms: D000164:Acremonium / Q000737:chemistry* / Q000378:metabolism; D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000962:Antimalarials / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D064210:Secondary Metabolism
chemical_list: D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000962:Antimalarials; D000970:Antineoplastic Agents; D000975:Antioxidants; D000998:Antiviral Agents; D004791:Enzyme Inhibitors; D007306:Insecticides
keywords: Acromonium fungi; alkaloids; bioactivities; marine organisms; secondary metabolites; β-lactam antibiotic