title: Feasibility and Safety of Robotic Peripheral Vascular Interventions: Results of the RAPID Trial.
abstract: The goal of this study was to evaluate the feasibility and safety of a robotic-assisted platform (CorPath 200, Corindus Vascular Robotics, Waltham, Massachusetts) for treating peripheral artery disease.
  
  
  
  A robotic-assisted platform for percutaneous coronary intervention is available for treating coronary artery disease.
  
  
  
  In this prospective single-arm trial, patients with symptomatic peripheral artery disease (Rutherford class 2 to 5) affecting the femoropoplital artery were enrolled. Endpoints evaluated were: 1) device technical success, defined as successful cannulation of the target vessel with the robotic system; 2) device safety, defined as absence of device related serious adverse event (hospitalization, prolonged hospitalization, life threatening, or resulted in death); and 3) clinical procedural success, defined as <50% residual stenosis without an unplanned switch to manual assistance or device-related serious adverse event in the periprocedural period.
  
  
  
  The study enrolled 20 subjects (65.5 ± 9.3 years of age; 70% male) with primarily Rutherford class 2 to 3 (90%) symptoms. A total of 29 lesions (lesion length: 33.1 ± 15.5 mm) were treated with the majority (89.7%) being located in the superficial femoral artery. Device technical success, safety and clinical procedural success were all 100% with provisional stenting required in 34.5% of lesions. Fluoroscopy time (7.1 ± 3.2 min) and contrast use (73.3 ± 9.2 ml) compared favorably with studies in similar patient cohorts. There were no adverse events associated with the use of the robotic system.
  
  
  
  These data demonstrate the feasibility and safety of using a robotic-assisted platform for performing peripheral arterial revascularization.
authors.affiliation: Division of Cardiovascular Medicine, Sulpizio Cardiovascular Center, University of California, San Diego, La Jolla, California. Electronic address: emahmud@ucsd.edu.
authors.forename: Ehtisham
authors.initials: E
authors.lastname: Mahmud
authors.affiliation: Division of Interventional Radiology, Medical University, Graz, Austria.
authors.forename: Florian
authors.initials: F
authors.lastname: Schmid
authors.affiliation: Division of Interventional Radiology, Medical University, Graz, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Kalmar
authors.affiliation: Division of Interventional Radiology, Medical University, Graz, Austria.
authors.forename: Hannes
authors.initials: H
authors.lastname: Deutschmann
authors.affiliation: Clinical Division of Angiologie, Medical University, Graz, Austria.
authors.forename: Franz
authors.initials: F
authors.lastname: Hafner
authors.affiliation: Clinical Division of Angiologie, Medical University, Graz, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Rief
authors.affiliation: Clinical Division of Angiologie, Medical University, Graz, Austria.
authors.forename: Marianne
authors.initials: M
authors.lastname: Brodmann
mesh_terms: D000368:Aged; D001317:Austria; D003251:Constriction, Pathologic; D003287:Contrast Media / Q000008:administration & dosage; D005240:Feasibility Studies; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D058729:Peripheral Arterial Disease / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011150:Popliteal Artery / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D015641:Radiography, Interventional; D065287:Robotic Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*
chemical_list: D003287:Contrast Media
keywords: PVI; interventions; peripheral artery disease; robotic assisted