title: Venous Thromboembolism in Brain Tumor Patients.
abstract: Venous thromboembolism (VTE) is a common medical condition, particularly after surgical interventions. Many studies have shown that development of VTE, including both deep vein thrombosis (DVT) and pulmonary embolism (PE), is more common in surgical patients with cancer than in patients without cancer. This chapter focuses on VTE in brain tumor patients, including their pathogenesis, presentation, diagnosis, and treatment. Topics discussed included a brief overview of VTE followed by an in-depth discussion of the VTE risks brain tumor patients face in the post-operative period. We conclude with a summary of various recommendations on VTE prophylaxis and a discussion of the controversial nature of VTE chemoprophylaxis for patients undergoing transcranial operations for brain tumors.
authors.affiliation: Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 15 Francis Street - PBB3, Boston, MA, 02115, USA.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Jeraq
authors.affiliation: Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 15 Francis Street - PBB3, Boston, MA, 02115, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Cote
authors.affiliation: Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 15 Francis Street - PBB3, Boston, MA, 02115, USA. trsmith@partners.org.
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Smith
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D048228:Intermittent Pneumatic Compression Devices; D019635:Neurosurgical Procedures / Q000009:adverse effects; D017410:Practice Guidelines as Topic; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D012307:Risk Factors; D053828:Stockings, Compression; D054556:Venous Thromboembolism / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy*
chemical_list: D000925:Anticoagulants; D006493:Heparin
keywords: Anti-coagulation; Brain surgery; Brain tumors; Deep venous thrombosis; Neurosurgery; Prophylaxis; Pulmonary embolism; Thromboprophylaxis; Venous thromboembolism