title: Targeting tyrosine receptor kinase B in gliomas.
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Kelly V
authors.initials: KV
authors.lastname: Pinheiro
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Camila
authors.initials: C
authors.lastname: Alves
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Marienela
authors.initials: M
authors.lastname: Buendia
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Mirela S
authors.initials: MS
authors.lastname: Gil
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Amanda
authors.initials: A
authors.lastname: Thomaz
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Gilberto
authors.initials: G
authors.lastname: Schwartsmann
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Caroline Brunetto
authors.initials: CB
authors.lastname: de Farias
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.). rafaelroesler@hcpa.edu.br rafael.roesler@pq.cnpq.br.
authors.forename: Rafael
authors.initials: R
authors.lastname: Roesler
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Robert L
authors.initials: RL
authors.lastname: Bowman
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Qianghu
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Angel
authors.initials: A
authors.lastname: Carro
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Roel G W
authors.initials: RG
authors.lastname: Verhaak
authors.affiliation: Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).
authors.forename: Massimo
authors.initials: M
authors.lastname: Squatrito
mesh_terms: D005910:Glioma; D006801:Humans; D010766:Phosphorylation; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases; D017459:Receptors, Amino Acid; D014443:Tyrosine
chemical_list: D017459:Receptors, Amino Acid; C087659:tyrosine receptor; D014443:Tyrosine; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases