title: [Pulmonary rehabilitation as an effective method for optimizing therapeutic and preventive measures in patients with chronic obstructive pulmonary disease concurrent with metabolic syndrome].
abstract: OBJECTIVE
  to evaluate the impact of a pulmonary rehabilitation (PR) cycle based on patient education, smoking cessation, physical exercises, and balanced nutrition in addition to standard therapy for chronic obstructive pulmonary disease COPD in patients with this condition.
  
  
  METHODS
  70 patients (27 (38.6%) women and 43 (61.4%) men) aged 18 to 60 years (mean age, 48.31±0.64 years) with moderate COPD in remission concurrent with MS were examined. The comprehensive examination of the patients encompassed assessment of clinical, instrumental, and laboratory findings at baseline and 12 months. The patients were randomized into two groups: 1) 35 patients who underwent a RH cycle in addition to standard therapy for COPD; 2) 35 patients who received standard COPD treatment only.
  
  
  RESULTS
  Group 1 was found to have significant differences in reducing the number of patients with COPD exacerbations, emergency calls, hospitalizations, severity of clinical symptoms of COPD and their impact on the physical activity and health of the patients, as well as better quality of life and exercise tolerance.
  
  
  CONCLUSIONS
  The therapeutic and preventive measures for patients with COPD and MS should involve educational programs and physical trainings, which are developed, by taking into account of a comorbidity in order to optimize therapeutic and preventive measures and to improve quality of life in this category of patients.
authors.affiliation: N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia, Voronezh, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Budnevsky
authors.affiliation: N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia, Voronezh, Russia.
authors.forename: Ya V
authors.initials: YV
authors.lastname: Isaeva
authors.affiliation: N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia, Voronezh, Russia.
authors.forename: E Yu
authors.initials: EY
authors.lastname: Malysh
authors.affiliation: N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia, Voronezh, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Kozhevnikova
mesh_terms: D015897:Comorbidity; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D062072:Patient Acuity; D010353:Patient Education as Topic / Q000379:methods*; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation; D011788:Quality of Life; D012129:Respiratory Function Tests / Q000379:methods; D016540:Smoking Cessation / Q000379:methods*; D063189:Symptom Assessment; D016896:Treatment Outcome