Evaluation of pituitary function in cases with the diagnosis of pediatric mild traumatic brain injury: Cross-sectional study.
BACKGROUND
This study was to determine whether pituitary dysfunction occurs after head trauma in children or not and which axis is affected more; to define the association of pituitary dysfunction with the severity of head trauma and duration time after the diagnosis of head trauma.


METHODS
In this study, 24 children who were diagnosed with head trauma were evaluated regarding pituitary dysfunction. In all cases, after 12 h fasting, serum cortisol, fT3, fT4, thyroid-stimulating hormone, prolactin, insulin-like growth factor-1, serum sodium, urine density, follicle-stimulating hormone, luteinizing hormone, in female cases E2, in male cases, TT levels were determined.


RESULTS
Mean age of children was 9.5 ± 3.1 years, 14 children (58.3%) had mild, 9 children (37.5%) had moderate, and 1 children (4.2%) had severe head trauma according to the Glasgow coma scale. Mean duration time after head trauma was 29.4 ± 9.8 months. In all cases, no pathologic condition was determined in the pituitary hormonal axis. In one children (4.2%), low basal cortisol level was found. There were no children with hormonal deficiency in this study.


CONCLUSIONS
Although pituitary dysfunction after head trauma may develop in the early period, some may present in the late period; therefore, all cases should be followed up at outpatient clinics for a longer period.
Department of Pediatrics, School of Medicine, Trakya University, Edirne, Turkey.
Hakan
H
Aylanç
Department of Pediatric Endocrinology, School of Medicine, Trakya University, Edirne, Turkey.
Filiz
F
Tütüncüler
Department of Biostatistics and Medical Informatics, School of Medicine, Trakya University, Edirne, Turkey.
Necdet
N
Süt
Child; head trauma; pituitary dysfunction; traumatic brain injury
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