Gastric GIST or gastric schwannoma-A diagnostic dilemma in a young female.
BACKGROUND
Gastrointestinal stromal tumor (GIST) is the commonest mesenchymal tumor of GI tract and 60-70% of it seen in the stomach, whereas Gastric schwannoma is a benign, slow growing and one of the rare neoplasms of stomach. Age distribution, clinical, radiological features and gross appearance of both tumors are similar.


METHODS
We report a rare case of gastric schwannoma in a 20-year-old girl, who underwent subtotal gastrectomy with the suspicion of a GIST preoperatively but later confirmed to be gastric schwannoma postoperatively after immunohistochemical study.


CONCLUSIONS
Accordingly, the differential diagnosis for gastric submucosal mass should be gastric schwannoma. Furthermore, Gastric schwannoma is a benign neoplasm with excellent prognosis after surgical resection, whereas 10-30% of GIST has malignant behavior. Therefore, it is important to distinguish between gastric schwannoma and GIST so as to make an accurate diagnosis for optimally guide treatment options.


CONCLUSIONS
Due to the paucity of gastric schwannoma, the index of suspicion for this diagnosis is low. So it is important to include gastric schwannoma in the differential diagnosis when preoperative imaging studies reveal submucosal exophytic gastric mass and after resection of the tumor with a negative margin, it should be sent for immunohistochemical study for confirmation of diagnosis.
Department of General Surgery, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: sudhirsandhya2021@gmail.com.
Sudhir Kumar
SK
Mohanty
Department of General Surgery, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: drmaniinbbsr@gmail.com.
Kumarmani
K
Jena
Department of General Surgery, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: drtanmaya1987@gmail.com.
Tanmaya
T
Mahapatra
Department of General Surgery, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: drjrd88@gmail.com.
Jyoti Ranjan
JR
Dash
Department of General Surgery, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: dibyasingh54@gmail.com.
Dibyasingh
D
Meher
Department of General Surgery, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: dr.ajaxjohn00@gmail.com.
Ajax
A
John
Department of Pathology, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: dr.manjushreenayak@gmail.com.
Manjushree
M
Nayak
Department of Pathology, S.C.B. Medical College, Cuttack, Odisha, 753007, India. Electronic address: shafqat.bano@gmail.com.
Shafqat
S
Bano
CD117; GIST; Immunohistochemichal study; S100; Schwannoma
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