The α7 nicotinic acetylcholine receptor agonist tropisetron counteracts ultraviolet A-mediated oxidative stress in human dermal fibroblasts.
Department of Dermatology, University of Münster, Münster, Germany.
Agatha
A
Stegemann
Department of Dermatology, University of Münster, Münster, Germany.
Markus
M
Böhm
D001952:Bridged-Ring Compounds / Q000494:pharmacology; D002374:Catalase / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D005347:Fibroblasts / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D020781:Matrix Metalloproteinase 1 / Q000378:metabolism; D019278:Matrix Metalloproteinase 3 / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects* / Q000528:radiation effects; D010865:Pilot Projects; D015595:Skin Aging / Q000187:drug effects*; D013141:Spiro Compounds / Q000494:pharmacology; D000077526:Tropisetron; D014466:Ultraviolet Rays; D064569:alpha7 Nicotinic Acetylcholine Receptor / Q000819:agonists*
C408128:AR-R 17779; D001952:Bridged-Ring Compounds; D007211:Indoles; D013141:Spiro Compounds; D064569:alpha7 Nicotinic Acetylcholine Receptor; D000077526:Tropisetron; D002374:Catalase; C511768:MMP3 protein, human; D019278:Matrix Metalloproteinase 3; C522360:MMP1 protein, human; D020781:Matrix Metalloproteinase 1
alpha7 acetylcholine receptor; antioxidative; oxidative stress; photoaging; ultraviolet A