Polymicrobial infections involving clinically relevant Gram-negative bacteria and fungi.
Interactions between fungi and bacteria and their relevance to human health and disease have recently attracted increased attention in biomedical fields. Emerging evidence shows that bacteria and fungi can have synergistic or antagonistic interactions, each with important implications for human colonization and disease. It is now appreciated that some of these interactions may be strategic and helps promote the survival of one or both microorganisms within the host. This review will shed light on clinically relevant interactions between fungi and Gram-negative bacteria. Mechanism of interaction, host immune responses, and preventive measures will also be reviewed.
Biomedicine Discovery Institute, Department of Microbiology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
Sanjiveeni
S
Dhamgaye
Biomedicine Discovery Institute, Department of Microbiology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.|Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Yue
Y
Qu
Biomedicine Discovery Institute, Department of Microbiology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.|Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Anton Y
AY
Peleg
D000898:Antibiosis / Q000502:physiology; D001422:Bacterial Adhesion; D018441:Biofilms / Q000254:growth & development*; D060085:Coinfection; D005204:Farnesol / Q000378:metabolism; D005658:Fungi / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity*; D006090:Gram-Negative Bacteria / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity*; D016905:Gram-Negative Bacterial Infections / Q000276:immunology* / Q000382:microbiology; D054884:Host-Pathogen Interactions; D007777:Lactobacillaceae / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity*; D009181:Mycoses / Q000276:immunology* / Q000382:microbiology; D010619:Phenazines / Q000378:metabolism; D013559:Symbiosis / Q000502:physiology; D010738:Type C Phospholipases / Q000096:biosynthesis / Q000378:metabolism; D014774:Virulence
D010619:Phenazines; D005204:Farnesol; D010738:Type C Phospholipases