Successful Delivery in a 39-Year-Old Patient with Anal Cancer after Fertility-Preserving Surgery Followed by Primary Chemoradiation and Low Anti-Mullerian Hormone Level.
Anal cancer was diagnosed in a 36-year-old nulliparous woman. Before chemoradiation was started, ovarian transposition and uterine fixation were performed in order to preserve capability for future parenthood. Despite of a low anti-Mullerian hormone level, IVF therapy was successful and resulted in a full-term delivery of a healthy baby by cesarean section. This is the first case report of successful pregnancy after full-dose pelvic radiation for anal cancer.
Department of Advanced Operative and Oncologic Gynecology, Asklepios Hospital Hamburg, Hamburg, Germany.
Christhardt
C
Köhler
Simone
S
Marnitz
Peter
P
Biel
Tim
T
Cordes
D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001005:Anus Neoplasms / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D059248:Chemoradiotherapy / Q000379:methods*; D005260:Female; D059247:Fertility Preservation / Q000379:methods*; D005307:Fertilization in Vitro; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D050498:Live Birth; D016685:Mitomycin / Q000008:administration & dosage; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010053:Ovary / Q000601:surgery; D011247:Pregnancy; D014599:Uterus / Q000601:surgery
D016685:Mitomycin; D054304:Anti-Mullerian Hormone; D005472:Fluorouracil