Rapid biosensing tools for cancer biomarkers.
The present review critically discusses the latest developments in the field of smart diagnostic systems for cancer biomarkers. A wide coverage of recent biosensing approaches involving aptamers, enzymes, DNA probes, fluorescent probes, interacting proteins and antibodies in vicinity to transducers such as electrochemical, optical and piezoelectric is presented. Recent advanced developments in biosensing approaches for cancer biomarker owes much credit to functionalized nanomaterials due to their unique opto-electronic properties and enhanced surface to volume ratio. Biosensing methods for a plenty of cancer biomarkers has been summarized emphasizing the key principles involved.
Laboratory of Bioluminescent Biotechnologies, Department of Biophysics, Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 79 Svobodny prospect, Krasnoyarsk 660041, Russia.
Rajeev
R
Ranjan
Laboratory of Bioluminescent Biotechnologies, Department of Biophysics, Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 79 Svobodny prospect, Krasnoyarsk 660041, Russia; Institute of Biophysics SB RAS, Akademgorodok 50/50, Krasnoyarsk 660036, Russia. Electronic address: esimbekova@yandex.ru.
Elena N
EN
Esimbekova
Laboratory of Bioluminescent Biotechnologies, Department of Biophysics, Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 79 Svobodny prospect, Krasnoyarsk 660041, Russia; Institute of Biophysics SB RAS, Akademgorodok 50/50, Krasnoyarsk 660036, Russia.
Valentina A
VA
Kratasyuk
D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D015374:Biosensing Techniques / Q000191:economics / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D046210:Microfluidic Analytical Techniques / Q000191:economics / Q000295:instrumentation / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis*; D019095:Point-of-Care Systems; D013997:Time Factors
D014408:Biomarkers, Tumor
Biosensor; Cancer biomarker; Functional nanomaterials; Microfluidics; Point-of-care devices