Clinical spectrum and diagnostic pitfalls of multiple abnormal uptakes on bone scintigraphy.
Bone scintigraphy with technetium-99m (99mTc)-labeled diphosphonates is one of the most frequently performed radionuclide procedures. Accumulation of99mTc-labeled diphosphonate is well recognized to reflect conditions of accelerated bone turnover and metabolism. Therefore, it is a functional imaging modality for detecting metastatic bone tumors, metabolic bone disease, traumatic injury, and inflammation. This pictorial essay describes the possible patterns of distribution of abnormal uptake for differential diagnosis of metastatic bone tumor, as well as the diagnostic pitfalls of bone scintigraphy.
Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Fumihiro
F
Tsubaki
Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan. skur@med.kurume-u.ac.jp.
Seiji
S
Kurata
Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Shuji
S
Nagata
Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Kiminori
K
Fujimoto
Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Toshi
T
Abe
D001847:Bone Diseases / Q000000981:diagnostic imaging*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D004164:Diphosphonates; D006801:Humans; D011877:Radionuclide Imaging / Q000379:methods*; D019275:Radiopharmaceuticals; D013667:Technetium
D004164:Diphosphonates; D019275:Radiopharmaceuticals; D013667:Technetium
Bone scintigraphy; Metabolic disorder; Metastatic disease
Cancer. 1996 Oct 1;78(7):1388-94
8839543
J Nucl Med. 1993 Dec;34(12 ):2247-52
8254419
N Engl J Med. 2004 Apr 15;350(16):1655-64
15084698
Semin Nucl Med. 1997 Jul;27(3):291-305
9224668
Radiographics. 2003 Mar-Apr;23 (2):341-58
12640151
Semin Nucl Med. 2010 Jan;40(1):52-61
19958850
J Nucl Med. 1993 Dec;34(12 ):2241-6
8254418
J Natl Med Assoc. 2006 Jun;98 (6):950-3
16775919
Skeletal Radiol. 1989;18(7):493-505
2686039
Semin Nucl Med. 2013 Mar;43(2):102-13
23414826
J Nucl Med. 1993 Dec;34(12 ):2236-40
8254417
Eur J Radiol. 2014 Oct;83(10):1828-42
25043984
Semin Nucl Med. 2012 Jan;42(1):11-26
22117809