ANTISTAPHYBASE: database of antimicrobial peptides (AMPs) and essential oils (EOs) against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus.
Staphylococcus aureus and methicillin-resistant S. aureus are major pathogens. The antimicrobial peptides and essential oils (EOs) display narrow- or broad-spectrum activity against bacteria including these strains. A centralized resource, such as a database, designed specifically for anti-S. aureus/anti-methicillin-resistant S. aureus antimicrobial peptides and EOs is therefore needed to facilitate the comprehensive investigation of their structure/activity associations and combinations. The database ANTISTAPHYBASE is created to facilitate access to important information on antimicrobial peptides and essential peptides against methicillin-resistant S. aureus and S. aureus. At the moment, the database contains 596 sequences of antimicrobial peptides produced by diverse organisms and 287 essential oil records. It permits a quick and easy search of peptides based on their activity as well as their general, physicochemical properties and literature data. These data are very useful to perform further bioinformatic or chemometric analysis and would certainly be useful for the development of new drugs for medical use. The ANTISTAPHYBASE database is freely available at: https://www.antistaphybase.com/ .
Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia. zouheirabdelmajid@yahoo.fr.|Research Unit at Institute of Applied Biological Sciences Tunis (ISSBAT), Tunis, Tunisia. zouheirabdelmajid@yahoo.fr.
Abdelmajid
http://orcid.org/0000-0002-8212-0959
A
Zouhir
Faculty of Sciences of Gabes, University of gabes, Gabès, Tunisia.
Malek
M
Taieb
Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.|Research Unit at Institute of Applied Biological Sciences Tunis (ISSBAT), Tunis, Tunisia.
Mohamed Ashraf
MA
Lamine
Faculty of Sciences of Tunis, Université of El Manar , Tunis, Tunisia.
Ammar
A
Cherif
Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.|Research Unit at Institute of Applied Biological Sciences Tunis (ISSBAT), Tunis, Tunisia.
Taoufik
T
Jridi
Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.|Research Unit at Institute of Applied Biological Sciences Tunis (ISSBAT), Tunis, Tunisia.
Basma
B
Mahjoubi
Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.|Research Unit at Institute of Applied Biological Sciences Tunis (ISSBAT), Tunis, Tunisia.
Sarra
S
Mbarek
Institut des Nutraceutiques et des Aliments Fonctionnels (INAF), Université Laval, Quebec, Canada.
Ismail
I
Fliss
Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL, USA.
Adel
A
Nefzi
Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.|Research Unit at Institute of Applied Biological Sciences Tunis (ISSBAT), Tunis, Tunisia.
Khaled
K
Sebei
Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.|Research Unit at Institute of Applied Biological Sciences Tunis (ISSBAT), Tunis, Tunisia.
Jeannette
J
Ben Hamida
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D062313:Databases, Pharmaceutical; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects*; D009822:Oils, Volatile / Q000494:pharmacology*; D010455:Peptides / Q000737:chemistry / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D009822:Oils, Volatile; D010455:Peptides
Anti-MRSA EOs; Anti-MRSA peptides; Anti-S. aureus EOs; Anti-S. aureus peptides