Epidemiology of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli in Japan: Characteristics of community-associated versus healthcare-associated ESBL E. coli.
Data on community-associated extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (CA-ESBLEC) infections in Japan are scarce. We compared the clinical and microbiological epidemiology of CA-ESBLEC infections with that of healthcare-associated-ESBLEC infections among 76 patients with ESBLEC infections. We identified a high prevalence (26%) of CA-ESBLEC infections in Japan; only a small proportion (15%) of patients with CA-ESBLEC infections had recent exposure to antibiotics.
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: kayokohayakawa@gmail.com.
Kayoko
K
Hayakawa
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Maki
M
Nagamatsu
Department of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan.
Kazuhisa
K
Mezaki
Infection Control and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Yuko
Y
Sugiki
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Satoshi
S
Kutsuna
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Nozomi
N
Takeshita
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Kei
K
Yamamoto
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Momoko
M
Mawatari
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Yoshihiro
Y
Fujiya
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Norio
N
Ohmagari
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017714:Community-Acquired Infections / Q000453:epidemiology*; D003428:Cross Infection / Q000453:epidemiology*; D004926:Escherichia coli / Q000201:enzymology*; D004927:Escherichia coli Infections / Q000201:enzymology / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D018709:Statistics, Nonparametric; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases
Antimicrobial resistance; CTX-M; Community-associated; Escherichia coli