A new flavonol glycoside from the aerial parts of Epimedium koreanum Nakai.
A new prenylated flavonol glycoside (1) was isolated from a 95% methanol extract of the dried and powdered aerial parts of Epimedium koreanum Nakai (Herba Epimedii), along with seven previously known flavonoids (2-8). The chemical structure of the new compound (1) was established to be 5-hydroxy-4'-methoxy-8-(2-hydroxy-3-methyl-3-butenyl)flavone 3-O-α-l-rhamnopyranosyl-7-O-β-D-gluco pyranoside on the basis of spectroscopic methods. The antioxidant activities of these compounds were determined by the DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging assay and kaempferitrin (8) showed a high reactivity with DPPH.
a College of Pharmacy and Research Institute of Drug Development , Chonnam National University , Gwangju , Republic of Korea.
Fubo
F
Han
a College of Pharmacy and Research Institute of Drug Development , Chonnam National University , Gwangju , Republic of Korea.
Ik-Soo
IS
Lee
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification; D001713:Biphenyl Compounds; D034181:Epimedium / Q000737:chemistry*; D044948:Flavonols / Q000737:chemistry / Q000302:isolation & purification*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010851:Picrates; D035261:Plant Components, Aerial / Q000737:chemistry; D013057:Spectrum Analysis
D000975:Antioxidants; D001713:Biphenyl Compounds; D044948:Flavonols; D016166:Free Radical Scavengers; D006027:Glycosides; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl
Epimedium koreanum Nakai; antioxidant activity; flavonol glycoside