A case report of a deep surgical site infection with Terrisporobacter glycolicus/T. Mayombei and review of the literature.
BACKGROUND
There are increasing data regarding Terrisporobacter glycolicus as an emerging anaerobic pathogen. However, the few published cases to date usually report it as part of a polymicrobial infection. Here, we describe the first reported monomicrobial surgical site infection with this bacterium. Identification methods, taxonomy, and clinical management of this rarely identified pathogen are also discussed.


METHODS
A previously healthy 66-year-old sustained an open olecranon fracture of his left arm after trauma. He subsequently underwent open reduction and internal fixation (ORIF), with insertion of an olecranon locking plate and two locking screws. Ten days after surgery, the patient developed increasing pain at the surgical site and noted green discharge from the wound. Culture of the wound discharge yielded grew a pure Gram-positive anaerobe identified by the RapidANA® microbial identification system as C. difficile (profile 000010, 99.1 % probability). Reference laboratory testing identified the isolate as T. glycolicus/mayombei (previously designated as Clostridium glycolicum/mayombei) by 16S rRNA gene sequencing and as Clostridium glycolicum by MALDI-TOF mass spectrometry. The patient received an 8-week course of moxifloxacin and metronidazole with an excellent clinical response at 12 months' follow-up.


CONCLUSIONS
We describe the case of a deep surgical site infection with T. glycolicus/mayombei (formerly known as Clostridium glycolicum and Clostridium mayombei, respectively), which extends our knowledge of the clinical spectrum of this pathogen. The isolate was misidentified by phenotypic identification methods.
Division of Infectious Diseases and Department of Medical Microbiology, Glen site, McGill University Health Centre, 1001 Boulevard Décarie, Room E05. 1811.2, Montreal, Quebec, H4A 3J1, Canada. matthew.cheng@mail.mcgill.ca.|J.D. MacLean Centre for Tropical Diseases, McGill University Health Centre, Montreal, Canada. matthew.cheng@mail.mcgill.ca.
Matthew P
MP
Cheng
Laboratoire de santé publique du Québec, McGill University Health Centre, Montreal, Canada.
Marc-Christian
MC
Domingo
Laboratoire de santé publique du Québec, McGill University Health Centre, Montreal, Canada.
Simon
S
Lévesque
Division of Infectious Diseases and Department of Medical Microbiology, Glen site, McGill University Health Centre, 1001 Boulevard Décarie, Room E05. 1811.2, Montreal, Quebec, H4A 3J1, Canada.|J.D. MacLean Centre for Tropical Diseases, McGill University Health Centre, Montreal, Canada.
Cedric P
CP
Yansouni
Clostridium glycolicum; MALDI-TOF; PCR; Surgical site infection; Terrisporobacter glycolicus; Terrisporobacter mayombei
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