Antiseptics and Antibiotics for Surgical Wounds Healing by Secondary Intention: Summary of a Cochrane Review.
Do antiseptics and antibiotics benefit surgical wounds healing by secondary intention (SWHSI)?



No high-quality randomized clinical trials have addressed this question. Current evidence is limited and insufficient; it is uncertain whether treating SWHSI with antiseptics or antibiotics is beneficial.
Division of Nursing, Midwifery and Social Work, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, England.
Gill
G
Norman
Division of Nursing, Midwifery and Social Work, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, England.
Jo C
JC
Dumville
Institute of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, England3Department of Obstetrics and Gynaecology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, England.
Emma J
EJ
Crosbie
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000009:adverse effects; D004338:Drug Combinations; D019317:Evidence-Based Medicine; D017408:Guidelines as Topic; D006801:Humans; D006997:Hypochlorous Acid / Q000008:administration & dosage; D007455:Iodine / Q000008:administration & dosage; D009779:Occlusive Dressings; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D012973:Sodium Hypochlorite / Q000008:administration & dosage; D013392:Sucralfate / Q000008:administration & dosage; D013514:Surgical Procedures, Operative; D013530:Surgical Wound Infection / Q000628:therapy*; D014260:Triclosan / Q000008:administration & dosage; D014945:Wound Healing / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; C554598:dermacyn; D014260:Triclosan; D013392:Sucralfate; D006997:Hypochlorous Acid; D007455:Iodine; D012973:Sodium Hypochlorite