Comparison of oral Lactobacillus and Streptococcus mutans between diabetic dialysis patients with non-diabetic dialysis patients and healthy people.
BACKGROUND
Diabetes is associated with higher rates of caries, on the other hand some studies have shown that renal failure can be protective against dental caries.


OBJECTIVE
In this study we compared oral Lactobacillus and Streptococcus mutans between diabetic dialysis and non-diabetic dialysis patients and the normal population.


METHODS
During November 2014 to January 2014, 85 people that referred to our medical care center entered the study. The sample included 30 diabetic dialysis, 28 non-diabetic dialysis patients and 27 healthy people. Oral saliva samples were obtained from their tongue and oral floor for microbiological examination. Patients' data were compared before and after dialysis.


RESULTS
The amount of Lactobacillus and S. mutans did not show a significant difference between the three groups (P=0.092 and P=0.966 for S. mutans and lactobacillus, respectively). A positive and meaningful correlation was seen between fasting blood sugar (FBS) levels and the amount of S. mutans in the diabetic dialysis group (P=0.023; r=0.413). A meaningful and positive correlation was also seen between the amount of blood urea nitrogen (BUN) after dialysis and the amount of oral S. mutans in the non-diabetic dialysis group (P=0.03; r=0.403).


CONCLUSIONS
Despite the differences in the prevalence of caries that have been reported between renal failure patients and diabetic patients, we did not find any significant difference between diabetic dialysis, non-diabetic dialysis patients and the healthy population, regarding their amount of oral cariogenic bacteria.
Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Fahimeh
F
Rezazadeh
Department of Bacteriology and Virology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
Abdollah
A
Bazargani
Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Jamshid
J
Roozbeh-Shahroodi
Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali
A
Pooladi
Non communicable Disease Research Center, Fasa University of Medical Sciences, Fasa, Iran ; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Peyman
P
Arasteh
Department of Bacteriology and Virology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
Khosro
K
Zamani
Dental caries; Diabetes mellitus; Dialysis; Lactobacillus; Renal failure; Streptococcus mutans
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