Cytomegalovirus sinusitis complicated by orbital apex syndrome in an immunocompromised host.
Sinusitis in immunocompromised patients can be caused by a wide variety of pathogens, primarily bacterial and fungal in nature. Tissue invasion can extend into the orbital apex and result in ophthalmoplegia and blindness. We report the first histologically proven case, to our knowledge, caused by cytomegalovirus infection.
Division of Infectious Diseases, Kaiser Permanente Medical Center, Los Angeles, CA, USA.
Jim H
JH
Nomura
Department of Ophthalmology, Kaiser Permanente Medical Center, Los Angeles, CA, USA.
Knut
K
Eichhorn
Bone Marrow Transplant, Kaiser Permanente Medical Center, Los Angeles, CA, USA.
Thai M
TM
Cao
Bone Marrow Transplant, Kaiser Permanente Medical Center, Los Angeles, CA, USA.
Firoozeh
F
Sahebi
D000368:Aged; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D001766:Blindness / Q000209:etiology; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000821:virology; D004172:Diplopia / Q000209:etiology; D005094:Exophthalmos / Q000209:etiology; D017245:Foscarnet / Q000008:administration & dosage / Q000627:therapeutic use; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009915:Orbit / Q000000981:diagnostic imaging / Q000601:surgery; D012852:Sinusitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000821:virology; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014184:Transplantation, Homologous / Q000009:adverse effects; D020432:Trochlear Nerve Diseases / Q000209:etiology; D019562:Viral Load; D014775:Virus Activation; D015354:Vision, Low / Q000209:etiology
D000998:Antiviral Agents; D017245:Foscarnet
cytomegalovirus; orbital apex syndrome; sinusitis