AcCNET (Accessory Genome Constellation Network): comparative genomics software for accessory genome analysis using bipartite networks.
AcCNET (Accessory genome Constellation Network) is a Perl application that aims to compare accessory genomes of a large number of genomic units, both at qualitative and quantitative levels. Using the proteomes extracted from the analysed genomes, AcCNET creates a bipartite network compatible with standard network analysis platforms. AcCNET allows merging phylogenetic and functional information about the concerned genomes, thus improving the capability of current methods of network analysis. The AcCNET bipartite network opens a new perspective to explore the pangenome of bacterial species, focusing on the accessory genome behind the idiosyncrasy of a particular strain and/or population.



AcCNET is available under GNU General Public License version 3.0 (GPLv3) from http://sourceforge.net/projects/accnet CONTACT: : valfernandez.vf@gmail.comSupplementary information: Supplementary data are available at Bioinformatics online.
Department of Microbiology, Ramón y Cajal University Hospital, Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain.|Join Unit of Antibiotic Resistance and Bacterial Virulence Associated with the Spanish National Research Council (CSIC).|CIBER in Epidemiology and Public Health (CIBER-ESP), Madrid, Spain.
Val F
VF
Lanza
Department of Microbiology, Ramón y Cajal University Hospital, Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain.|Join Unit of Antibiotic Resistance and Bacterial Virulence Associated with the Spanish National Research Council (CSIC).|CIBER in Epidemiology and Public Health (CIBER-ESP), Madrid, Spain.
Fernando
F
Baquero
Departamento de Biología Molecular, Universidad de Cantabria and Instituto de Biomedicina y Biotecnología de Cantabria IBBTEC (UC-CSIC), Santander, Spain.
Fernando
F
de la Cruz
Department of Microbiology, Ramón y Cajal University Hospital, Ramón y Cajal Health Research Institute (IRYCIS), Madrid, Spain.|Join Unit of Antibiotic Resistance and Bacterial Virulence Associated with the Spanish National Research Council (CSIC).|CIBER in Epidemiology and Public Health (CIBER-ESP), Madrid, Spain.
Teresa M
TM
Coque
D001419:Bacteria / Q000235:genetics; D016680:Genome, Bacterial; D023281:Genomics / Q000379:methods*; D054892:Metagenome; D010802:Phylogeny; D020543:Proteome; D012984:Software
D020543:Proteome