The enduring legacy of Alfred Gilman senior (1908-1984) to pharmacology and clinical medicine.
Alfred Gilman was best known for his co-authorship with Louis Goodman of the seminal textbook on pharmacology The Pharmacological Basis of Therapeutics in 1941. The book made the discipline of pharmacology relevant to clinical medicine by providing a link between the basic medical sciences and the practice of medicine. Gilman was also instrumental in establishing the use of chemotherapy in the treatment of cancer and made important contributions in areas related to renal function, acid-base balance, and diuretics. During the 1960s, he created a first rate department at the newly formed Albert Einstein College of Medicine. A superb lecturer, he commented incisively on issues related to pharmacology, therapeutics, and pathophysiology. Dr Gilman also provided a key link between academia and the pharmaceutical industry by serving as a consultant to several drug firms. The legacy of Alfred Gilman senior was continued by his son, Alfred Goodman Gilman, who became a Nobel Laureate.
Department of Pharmacology & Toxicology, Jacobs School of Medicine & Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Ronald P
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Rubin
D015510:Clinical Medicine / Q000266:history*; D003237:Connecticut; D049673:History, 20th Century; D009518:New York; D010600:Pharmacology / Q000266:history*; D014481:United States
Albert Einstein College of Medicine; Alfred Gilman; Bible of Pharmacology; chemotherapy