Skeletonization of Left Internal Mammary Artery in Coronary Artery Bypass Grafting.
OBJECTIVE
To compare mean per-operative flow capacity between skeletonized and pedicled left internal mammary artery (LIMA) in patients undergoing coronary artery bypass grafting (CABG) surgery.


METHODS
Randomized control trial.


METHODS
Department of Cardiac Surgery, Armed Forces Institute of Cardiology and National Institute of Heart Diseases (AFIC-NIHD), Rawalpindi, Pakistan from February to August, 2013.


METHODS
Patients undergoing CABG for coronary artery disease, under 80 years, excluded by the exclusion criteria; and fulfilling the inclusion criteria were randomly assigned to two groups of 70 each. One group underwent skeletonized and the other underwent pedicled technique of LIMAharvesting. Free flow was checked just before anastamosis of each LIMAto the LAD, manually in blood flow in ml per minute during cardiopulmonary bypass by allowing it to bleed into a 100 ml container over 20 seconds. Aspecialized proforma was used to record the age, gender, weight, disease, type of IMA used, and free flow of the IMA. Data was analyzed using SPSS 18.


RESULTS
The mean age of the patients was 57.16 years in 40 patients, ranging from 36 to 75 years. Disease pattern analysis showed 5%, 10.7% and 84.3% single, double and triple vessel coronary artery disease, respectively. There was significantly higher free flow in the skeletonized group than the pedicled group (p=0.04).


CONCLUSIONS
Skeletonized IMAhad superior flow to pedicled IMAin addition to its traditional proven advantages, which justifies its further use as a conduit for myocardial revascularization.
Department of Cardiac Surgery,Armed Forces Institute of Cardiology and National Institute of Heart Diseases (AFIC-NIHD), Rawalpindi.
Muhammad Sohail
MS
Chaudhri
Department of Cardiac Surgery,Armed Forces Institute of Cardiology and National Institute of Heart Diseases (AFIC-NIHD), Rawalpindi.
Muhammad Usman Ali
MU
Shah
Department of Cardiac Surgery,Armed Forces Institute of Cardiology and National Institute of Heart Diseases (AFIC-NIHD), Rawalpindi.
Muhammad Imran
MI
Asghar
Department of Cardio-Thoracic Anesthesia,Armed Forces Institute of Cardiology and National Institute of Heart Diseases (AFIC-NIHD), Rawalpindi.
Rashad
R
Siddiqi
Department of Cardiac Surgery,Armed Forces Institute of Cardiology and National Institute of Heart Diseases (AFIC-NIHD), Rawalpindi.
Asif Mahmood
AM
Janjua
Department of Cardiac Surgery,Armed Forces Institute of Cardiology and National Institute of Heart Diseases (AFIC-NIHD), Rawalpindi.
Afsheen
A
Iqbal
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002315:Cardiopulmonary Bypass; D015331:Cohort Studies; D001026:Coronary Artery Bypass / Q000379:methods*; D003324:Coronary Artery Disease / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007387:Internal Mammary-Coronary Artery Anastomosis / Q000379:methods*; D008297:Male; D008323:Mammary Arteries / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D010154:Pakistan; D019275:Radiopharmaceuticals; D012039:Regional Blood Flow / Q000502:physiology*; D020858:Tissue and Organ Harvesting / Q000379:methods*; D016896:Treatment Outcome; D018924:Vascular Capacitance / Q000502:physiology; D014654:Vascular Patency / Q000502:physiology
D019275:Radiopharmaceuticals