Risk assessment instruments for screening bone mineral density in a Mediterranean population.
OBJECTIVE
To evaluate the power of six osteoporosis-screening instruments in women in a Mediterranean country.


METHODS
Data concerning several osteoporosis risk factors were prospectively collected from 1000 postmenopausal women aged 42-87 years who underwent dual-energy X-ray absorptiometry (DEXA) screening. Six osteoporosis risk factor screening tools were applied to this sample to evaluate their performance and choose the most appropriate tool for the study population.


RESULTS
The most important screening tool for osteoporosis status was the Simple Calculated Osteoporosis Risk Estimation, which had an area under the curve (AUC) of 0.678, a sensitivity of 72%, and a specificity of 72%, with a cut-off point of 20.75. The most important screening tool for osteoporosis risk was the Osteoporosis Self-assessment Tool, which had an AUC of 0.643, a sensitivity of 77%, and a specificity of 46%, with a cut-off point of -2.9.


CONCLUSIONS
Some commonly used clinical risk instruments demonstrate high sensitivity for distinguishing individuals with DEXA-ascertained osteoporosis or reduced bone mineral density.
Sotirios Christodoulou, Georgios I Drosos, Athanasios Ververidis, Konstantinos Kazakos, Department of Orthopaedic Surgery, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, 68100 Alexandroupolis, Greece.
Sotirios
S
Christodoulou
Sotirios Christodoulou, Georgios I Drosos, Athanasios Ververidis, Konstantinos Kazakos, Department of Orthopaedic Surgery, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, 68100 Alexandroupolis, Greece.
Georgios I
GI
Drosos
Sotirios Christodoulou, Georgios I Drosos, Athanasios Ververidis, Konstantinos Kazakos, Department of Orthopaedic Surgery, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, 68100 Alexandroupolis, Greece.
Athanasios
A
Ververidis
Sotirios Christodoulou, Georgios I Drosos, Athanasios Ververidis, Konstantinos Kazakos, Department of Orthopaedic Surgery, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, 68100 Alexandroupolis, Greece.
Antonios
A
Galanos
Sotirios Christodoulou, Georgios I Drosos, Athanasios Ververidis, Konstantinos Kazakos, Department of Orthopaedic Surgery, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, 68100 Alexandroupolis, Greece.
George
G
Anastassopoulos
Sotirios Christodoulou, Georgios I Drosos, Athanasios Ververidis, Konstantinos Kazakos, Department of Orthopaedic Surgery, Democritus University of Thrace, University General Hospital of Alexandroupolis, Dragana, 68100 Alexandroupolis, Greece.
Konstantinos
K
Kazakos
Bone mineral density; Dual X-ray absorptiometry; Osteopenia; Osteoporosis; Risk assessment
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