Exercising control over bipolar disorder.
Following extensive research exercise has emerged as an effective treatment for major depressive disorder, and it is now a recognised therapy alongside other interventions. In contrast, there is a paucity of research examining the therapeutic effects of exercise for those with bipolar disorder. Given that dysfunctional reward processing is central to bipolar disorder, research suggests that exercise can perhaps be framed as a reward-related event that may have the potential to precipitate a manic episode. The behavioural activation system (BAS) is a neurobehavioural system that is associated with responding to reward and provides an appropriate framework to theoretically examine and better understand the effects of exercise treatment on bipolar disorder. This article discusses recent research findings and provides an overview of the extant literature related to the neurobiological underpinnings of BAS and exercise as they relate to bipolar disorder. This is important clinically because depending on mood state in bipolar disorder, we postulate that exercise could be either beneficial or deleterious with positive or negative effects on the illness. Clearly, this complicates the evaluation of exercise as a potential treatment in terms of identifying its optimal characteristics in this population.
Academic Department of Psychiatry, Kolling Institute, Northern Sydney Local Health District, St Leonards, New South Wales, Australia.|Sydney Medical School Northern, University of Sydney, Sydney, New South Wales, Australia.|CADE Clinic, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales, Australia.
Gin S
GS
Malhi
Academic Department of Psychiatry, Kolling Institute, Northern Sydney Local Health District, St Leonards, New South Wales, Australia.|Sydney Medical School Northern, University of Sydney, Sydney, New South Wales, Australia.|CADE Clinic, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, New South Wales, Australia.
Yulisha
Y
Byrow
D001519:Behavior / Q000502:physiology; D032763:Behavior Control / Q000379:methods; D035843:Biomedical Research / Q000639:trends; D001714:Bipolar Disorder / Q000503:physiopathology / Q000628:therapy*; D001921:Brain / Q000502:physiology; D003863:Depression / Q000628:therapy; D005081:Exercise Therapy; D005544:Forecasting; D006801:Humans
Soc Cogn Affect Neurosci. 2016 Aug;11(8):1310-6
27053768
J Affect Disord. 2014 Aug;165:24-30
24882173
J Affect Disord. 2012 Feb;136(3):634-42
22100131
Bipolar Disord. 2015 Dec;17 Suppl 2:3-20
26688287
Clin Psychol Rev. 2008 Oct;28(7):1188-205
18565633
Cochrane Database Syst Rev. 2013 Sep 12;(9):CD004366
24026850
Cogn Behav Ther. 2015;44(4):341-52
25794191
Psychother Psychosom. 2010;79(2):87-96
20051706
Can J Psychiatry. 2016 Sep;61(9):576-87
27486153
Dev Psychol. 2012 Sep;48(5):1488-500
22390662
Int J Bipolar Disord. 2013 Oct 1;1(1):24
24660139
Front Psychol. 2015 Mar 04;6:147
25788889
PLoS One. 2014 Jun 17;9(6):e100100
24936656
J Psychopharmacol. 2015 May;29(5):459-525
25969470
J Affect Disord. 2012 Dec 20;143(1-3):196-202
22884233
J Affect Disord. 2007 Aug;101(1-3):259-62
17182104
Neurosci Biobehav Rev. 2016 Feb;61:1-11
26657969
J Consult Clin Psychol. 1996 Apr;64(2):295-304
8871414
Curr Dir Psychol Sci. 2010 Jun 1;19(3):189-194
20606725
J Psychiatr Res. 2015 Feb;61:25-32
25439084
Aust N Z J Psychiatry. 2015 Dec;49(12):1087-206
26643054
Transl Psychiatry. 2016 May 17;6:e814
27187236
Curr Opin Psychiatry. 2015 Jan;28(1):7-12
25415499
Community Ment Health J. 2010 Dec;46(6):540-52
20012197
J Abnorm Psychol. 2012 May;121(2):339-351
22004113