Heightened early-attentional stimulus orienting and impulsive action in men with antisocial personality disorder.
We tested whether enhanced stimulus orienting operationalized as N1 and P2 auditory evoked potentials to increasing loudness (50-90 dB clicks) could be associated with trait impulsivity (Barratt Impulsiveness Scale, BIS-11), impulsive action (commission error on the Immediate Memory Task), or impulsive choice (immediate responses on temporal discounting tasks). We measured N1 and P2 loudness sensitivity in a passive listening task as linear intensity-sensitivity slopes in 36 men with antisocial personality disorder with a history of conviction for criminal conduct and 16 healthy control men. Across all subjects, regression analyses revealed that a steeper P2 slope predicted higher IMT commission error/correct detection ratio, and lower stimulus discriminability (A-prime). These associations were also found within both groups. These relationships suggest an association between enhanced early stimulus orienting (P2), impulsive action (response inhibition), and impaired signal-noise discriminability (A-prime).
Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Blvd, Houston, TX, 77030, USA. Marijn.Lijffijt@bcm.edu.
Marijn
http://orcid.org/0000-0001-5760-1729
M
Lijffijt
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1941 East Road, Houston, TX, 77030, USA.
Scott D
SD
Lane
Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Blvd, Houston, TX, 77030, USA.|Mental Health Care Line, Michael E. DeBakey VA Medical Center, Houston, TX, USA.
Sanjay J
SJ
Mathew
Hope and Healing Center, 717 Sage Road, Houston, TX, 77056, USA.
Matthew S
MS
Stanford
Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Blvd, Houston, TX, 77030, USA.|Mental Health Care Line, Michael E. DeBakey VA Medical Center, Houston, TX, USA.
Alan C
AC
Swann
D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000503:physiopathology*; D001288:Attention / Q000502:physiology*; D004192:Discrimination, Psychological; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D006801:Humans; D007175:Impulsive Behavior / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011571:Psychoacoustics; D018709:Statistics, Nonparametric; D055815:Young Adult
Aggression; Augmenting–reducing; Conduct disorder; Crime; Evoked potential; Impulsivity
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