ArabidopsisFORGETTER1 mediates stress-induced chromatin memory through nucleosome remodeling.
Plants as sessile organisms can adapt to environmental stress to mitigate its adverse effects. As part of such adaptation they maintain an active memory of heat stress for several days that promotes a more efficient response to recurring stress. We show that this heat stress memory requires the activity of theFORGETTER1 (FGT1) locus, withfgt1mutants displaying reduced maintenance of heat-induced gene expression.FGT1encodes theArabidopsis thalianaorthologue of Strawberry notch (Sno), and the protein globally associates with the promoter regions of actively expressed genes in a heat-dependent fashion. FGT1 interacts with chromatin remodelers of the SWI/SNF and ISWI families, which also display reduced heat stress memory. Genomic targets of the BRM remodeler overlap significantly with FGT1 targets. Accordingly, nucleosome dynamics at loci with altered maintenance of heat-induced expression are affected infgt1. Together, our results suggest that by modulating nucleosome occupancy, FGT1 mediates stress-induced chromatin memory.
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Krzysztof
K
Brzezinka
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Simone
S
Altmann
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Hjördis
H
Czesnick
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Philippe
P
Nicolas
Max-Planck-Institute for Molecular Plant Physiology, Potsdam, Germany.
Michal
http://orcid.org/0000-0002-1289-6858
M
Gorka
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Eileen
E
Benke
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Tina
T
Kabelitz
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Felix
F
Jähne
Max-Planck-Institute for Molecular Plant Physiology, Potsdam, Germany.
Alexander
A
Graf
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Christian
http://orcid.org/0000-0002-1450-1864
C
Kappel
Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Isabel
http://orcid.org/0000-0001-5633-8068
I
Bäurle
A. thaliana; DExD/H helicase; chromatin memory; chromosomes; genes; heat stress; nucleosome remodeling; plant biology; priming
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