One-pot synthesis of nitrogen and sulfur co-doped carbon dots and its application for sensor and multicolor cellular imaging.
Nitrogen and sulfur co-doped carbon dots (N, S/C-dots) were prepared via one-pot hydrothermal treatment of citric acid and cystamine dihydrochloride. The as-prepared N, S/C-dots exhibited excellent excitation-wavelength-independent photoluminescence property and higher fluorescence quantum yield (QY) of 39.7% compared to C,N-dots (QY=2.6%) prepared using citric acid and 1,6-diaminohexane dihydrochloride as the precursor. The N, S/C-dots were well-dispersed in aqueous solution and showed good photoluminescence stabilities in different pH and temperature without any surface modification. Additionally, the fluorescence of N, S/C-dots can be quenched based on inner filter effect (IFE) upon the addition of Cr(VI) and showed good selectivity and sensitivity to Cr(VI). The detection for Cr(VI) exhibited a good linear correlation ranging from 1 to 80μM with a detection limit of 0.86μM. What's more, in comparison with other quantum dots and organic dyes, these N, S/C-dots were much more eco-friendly and can be used for multicolor bioimaging.
Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, China; Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. Electronic address: chenjc@swu.edu.cn.
Jiucun
J
Chen
Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, China.
Jianhua
J
Liu
Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, China.
Junzhi
J
Li
Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, China.
Liqun
L
Xu
Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, China.
Yajuan
Y
Qiao
D002244:Carbon / Q000737:chemistry*; D002857:Chromium / Q000032:analysis*; D019343:Citric Acid / Q000737:chemistry; D003538:Cystamine / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D008163:Luminescent Measurements; D057054:Molecular Imaging / Q000379:methods*; D009584:Nitrogen / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry* / Q000648:ultrastructure; D012996:Solutions; D013455:Sulfur / Q000737:chemistry*; D013696:Temperature; D014867:Water; D014873:Water Pollutants / Q000032:analysis*
D012996:Solutions; D014873:Water Pollutants; D014867:Water; D002857:Chromium; C074702:chromium hexavalent ion; D019343:Citric Acid; D013455:Sulfur; D002244:Carbon; D009584:Nitrogen; D003538:Cystamine
Bioimaging; Cr(VI) detection; Doped carbon dots; Fluorescence