NUCLEAR FACTOR Y, Subunit C (NF-YC) Transcription Factors Are Positive Regulators of Photomorphogenesis in Arabidopsis thaliana.
Recent reports suggest that NF-Y transcription factors are positive regulators of skotomorphogenesis in Arabidopsis thaliana. Three NF-YC genes (NF-YC3, NF-YC4, and NF-YC9) are known to have overlapping functions in photoperiod dependent flowering and previous studies demonstrated that they interact with basic leucine zipper (bZIP) transcription factors. This included ELONGATED HYPOCOTYL 5 (HY5), which has well-demonstrated roles in photomorphogenesis. Similar to hy5 mutants, we report that nf-yc3 nf-yc4 nf-yc9 triple mutants failed to inhibit hypocotyl elongation in all tested light wavelengths. Surprisingly, nf-yc3 nf-yc4 nf-yc9 hy5 mutants had synergistic defects in light perception, suggesting that NF-Ys represent a parallel light signaling pathway. As with other photomorphogenic transcription factors, nf-yc3 nf-yc4 nf-yc9 triple mutants also partially suppressed the short hypocotyl and dwarf rosette phenotypes of CONSTITUTIVE PHOTOMORPHOGENIC 1 (cop1) mutants. Thus, our data strongly suggest that NF-Y transcription factors have important roles as positive regulators of photomorphogenesis, and in conjunction with other recent reports, implies that the NF-Y are multifaceted regulators of early seedling development.
Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States of America.
Zachary A
http://orcid.org/0000-0002-7225-0290
ZA
Myers
Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States of America.
Roderick W
RW
Kumimoto
Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States of America.
Chamindika L
CL
Siriwardana
Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States of America.
Krystal K
http://orcid.org/0000-0001-6325-5594
KK
Gayler
Bioo Scientific, Austin, Texas, United States of America.
Jan R
http://orcid.org/0000-0002-2920-9591
JR
Risinger
Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States of America.
Daniela
http://orcid.org/0000-0002-3601-9876
D
Pezzetta
Department of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, United States of America.
Ben F
BF
Holt Iii
Plant Cell. 1999 Mar;11(3):349-64
10072396
Trends Cell Biol. 1999 Feb;9(2):48-52
10087617
Curr Biol. 1999 Oct 7;9(19):1127-30
10531012
J Biol Chem. 1999 Dec 10;274(50):36009-14
10585491
Genes Dev. 2000 Feb 1;14(3):257-71
10673498
Nat Genet. 2000 May;25(1):25-9
10802651
Plant Physiol. 2000 Sep;124(1):39-45
10982420
Genes Dev. 2000 Sep 15;14(18):2377-91
10995393
Plant Cell. 2000 Nov;12(11):2061-74
11090209
Plant Physiol. 2000 Dec;124(4):1520-4
11115869
Mol Cell Biol. 2001 Feb;21(4):1239-48
11158310
Genes Dev. 2001 Oct 1;15(19):2613-25
11581165
Plant Cell. 2001 Dec;13(12):2589-607
11752374
Nat Biotechnol. 2002 Jan;20(1):87-90
11753368
Plant J. 2001 Dec;28(6):619-31
11851908
Genes Dev. 2002 May 15;16(10):1247-59
12023303
Plant J. 2002 Jun;30(6):711-9
12061902
Plant Physiol. 2002 Sep;130(1):234-43
12226503
Plant Cell. 1994 Dec;6(12):1731-1745
12244233
Plant Cell. 1994 Aug;6(8):1049-1064
12244265
Plant Cell. 2002 Dec;14(12):2985-94
12468722
Plant Cell. 2003 Jan;15(1):5-18
12509518
Nature. 2003 Jun 26;423(6943):995-9
12827204
Science. 2003 Aug 1;301(5633):653-7
12893945
Nature. 2003 Dec 4;426(6966):567-70
14654842
Cell Cycle. 2004 Feb;3(2):217-22
14712092
New Phytol. 2005 Feb;165(2):623-31
15720672
Genes Dev. 2005 Mar 1;19(5):593-602
15741320
Mol Cell Biol. 2005 Jul;25(13):5339-54
15964792
Plant J. 2005 Aug;43(3):356-70
16045472
Genes Dev. 2005 Dec 1;19(23):2811-5
16322556
Plant Cell. 2006 Jan;18(1):70-84
16339850
Plant J. 2006 May;46(3):462-76
16623906
PLoS Genet. 2006 Jul;2(7):e106
16839183
Development. 2006 Aug;133(16):3213-22
16854975
Plant Cell Physiol. 2006 Aug;47(8):1023-34
16861711
Genes Dev. 2006 Nov 15;20(22):3084-8
17114582
Plant Cell. 2006 Nov;18(11):2971-84
17138697
Plant Physiol. 2007 Feb;143(2):902-11
17158584
Plant Physiol. 2007 Apr;143(4):1590-600
17322342
Plant Cell. 2007 Mar;19(3):731-49
17337630
Genes Dev. 2007 Aug 15;21(16):2100-11
17699755
Science. 1992 Dec 4;258(5088):1647-50
17742538
Plant Cell. 2007 Oct;19(10):3242-55
17965270
Science. 2007 Nov 23;318(5854):1302-5
18033885
Mol Cell Biol. 2008 Mar;28(6):2047-58
18212061
Plant Cell. 2008 Feb;20(2):292-306
18296627
EMBO J. 2008 Apr 23;27(8):1277-88
18388858
Planta. 2008 Oct;228(5):709-23
18600346
PLoS Genet. 2008 Aug 01;4(8):e1000143
18670649
Plant Cell. 2008 Sep;20(9):2324-38
18796637
Plant Physiol. 2009 Feb;149(2):625-41
19019982
Plant J. 2009 Jun;58(5):843-56
19207209
Bioinformatics. 2009 Jul 15;25(14):1754-60
19451168
Plant Cell. 2009 May;21(5):1341-59
19482971
Plant Signal Behav. 2008 Nov;3(11):986-8
19704428
Bioinformatics. 2010 Jan 1;26(1):139-40
19910308
Plant Cell. 2009 Nov;21(11):3416-20
19920209
Bioinformatics. 2010 Mar 1;26(5):589-95
20080505
Plant Cell. 2010 Mar;22(3):782-96
20207753
Plant J. 2010 Mar;61(6):982-91
20409272
Plant J. 2010 Aug;63(3):379-91
20487380
Plant Cell. 2010 Nov;22(11):3634-49
21097709
Plant Cell. 2010 Dec;22(12):4142-57
21139064
Plant J. 2011 Feb;65(3):346-58
21265889
Science. 2011 Apr 1;332(6025):103-6
21454788
PLoS One. 2011 Mar 29;6(3):e17896
21479270
J Biol Chem. 2011 Jul 15;286(28):25154-70
21592964
BMC Biotechnol. 2011 May 19;11:53
21595971
PLoS One. 2011;6(6):e21805
21738795
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16475-80
21930922
Biosci Biotechnol Biochem. 2011;75(10):2037-41
21979077
Mol Plant. 2012 Jul;5(4):876-88
22199235
Plant J. 2012 Aug;71(3):427-42
22429691
Nat Methods. 2012 Jun 28;9(7):676-82
22743772
J Biol Chem. 2012 Sep 7;287(37):31482-93
22801428
Trends Plant Sci. 2013 Mar;18(3):157-66
22939172
Plant Signal Behav. 2012 Dec;7(12):1718-20
23073004
PLoS One. 2012;7(10):e48138
23118940
Plant Cell. 2012 Nov;24(11):4590-606
23150635
Plant Cell. 2012 Dec;24(12):4777-92
23275578
Plant Cell Physiol. 2013 Jun;54(6):907-16
23503597
PLoS One. 2013;8(3):e59481
23527203
Genome Res. 2013 Aug;23(8):1195-209
23595228
Plant Cell. 2013 Apr;25(4):1243-57
23624715
Methods Mol Biol. 2014;1062:165-73
24057365
Plant Cell. 2013 Oct;25(10):3770-84
24179122
Front Plant Sci. 2013 Oct 29;4:413
24194740
Plant Physiol. 2014 Feb;164(2):841-52
24335334
Trends Plant Sci. 2014 Jul;19(7):460-70
24582145
PLoS Genet. 2014 Feb 27;10(2):e1004197
24586210
Plant Cell. 2014 Mar;26(3):1009-17
24610724
PLoS Genet. 2014 Jun 12;10(6):e1004416
24922306
Planta. 2014 Nov;240(5):1051-62
25074586
Nat Commun. 2014 Aug 08;5:4601
25105952
Plant Mol Biol Report. 2014;32(5):971-986
25190903
Nucleic Acids Res. 2015 Jan;43(Database issue):D1049-56
25428369
Enzymes. 2014;35:213-39
25740721
Genes Dev. 1989 Nov;3(11):1745-57
2606345
Mol Plant. 2016 Jan 4;9(1):113-125
26363272
Plant Physiol. 2015 Dec;169(4):2761-73
26432878
Plant Cell. 2015 Nov;27(11):3099-111
26566918
PLoS Genet. 2016 Dec 15;12(12):e1006496
27977687
Plant J. 1995 Mar;7(3):413-27
7757114
Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1624-8
7878029
Cell. 1994 Dec 16;79(6):1035-45
8001131
Plant Cell. 1994 May;6(5):613-28
8038602
Plant Cell. 1994 Apr;6(4):487-500
8205001
Mol Cell Biol. 1996 Jan;16(1):328-37
8524312
Genes Dev. 1997 Nov 15;11(22):2983-95
9367981
Gene. 1997 Oct 24;200(1-2):107-16
9373144
Annu Rev Cell Dev Biol. 1997;13:203-29
9442873
Plant Cell. 1998 May;10(5):673-83
9596629