Biologically Inspired C-H and C=C Oxidations with Hydrogen Peroxide Catalyzed by Iron Coordination Complexes.
The development of catalysts for the selective oxidation of readily available hydrocarbons or organic precursors into oxygenated products is a long-standing goal in organic synthesis. In the last decade, some iron coordination complexes have shown the potential to fit this role. These catalysts can mimic the O-O activation mode of far more sophisticated iron oxygenase enzymes, generating powerful yet selective oxidants. In this review, we report state-of-the-art C-H and C=C oxidations catalyzed by non-heme iron complexes and H2O2as the oxidant. Finally, we briefly describe some novel oxidative reactivity and the perspectives of this chemistry.
Departament de Química I Institut de Química Computacional i Catàlisi (IQCC), Universitat de Girona, Facultat de Ciències, Campus de Montilivi, Girona, 17071, Spain.
Giorgio
http://orcid.org/0000-0003-4053-7673
G
Olivo
Departament de Química I Institut de Química Computacional i Catàlisi (IQCC), Universitat de Girona, Facultat de Ciències, Campus de Montilivi, Girona, 17071, Spain.
Olaf
http://orcid.org/0000-0001-6578-3163
O
Cussó
Departament de Química I Institut de Química Computacional i Catàlisi (IQCC), Universitat de Girona, Facultat de Ciències, Campus de Montilivi, Girona, 17071, Spain.
Miquel
http://orcid.org/0000-0001-6326-8299
M
Costas
C−H activation; dihydroxylation; epoxidation; iron; oxidation