The effects on plasma L-arginine levels of combined oral L-citrulline and L-arginine supplementation in healthy males.
We investigated the effects of combining 1 g of l-citrulline and 1 g of l-arginine as oral supplementation on plasma l-arginine levels in healthy males. Oral l-citrulline plus l-arginine supplementation more efficiently increased plasma l-arginine levels than 2 g of l-citrulline or l-arginine, suggesting that oral l-citrulline and l-arginine increase plasma l-arginine levels more effectively in humans when combined.
a Healthcare Products Development Center , KYOWA HAKKO BIO CO.,LTD , Tsukuba , Japan.
Takashi
T
Suzuki
a Healthcare Products Development Center , KYOWA HAKKO BIO CO.,LTD , Tsukuba , Japan.
Masahiko
M
Morita
b Division of Health Science , Nagoya University Graduate School of Medicine , Nagoya , Japan.
Toshio
T
Hayashi
a Healthcare Products Development Center , KYOWA HAKKO BIO CO.,LTD , Tsukuba , Japan.
Ayako
A
Kamimura
D000284:Administration, Oral; D000328:Adult; D001120:Arginine / Q000008:administration & dosage / Q000097:blood* / Q000494:pharmacology*; D002956:Citrulline / Q000008:administration & dosage* / Q000494:pharmacology*; D019587:Dietary Supplements; D004347:Drug Interactions; D006801:Humans; D008297:Male; D055815:Young Adult
D002956:Citrulline; D001120:Arginine
combination effect; l-arginine, l-citrulline, human; oral intake