Biochemical and Biophysical Understanding of Metal Ion Selectivity of DNAzymes.
This review summarizes research into the metal-binding properties of catalytic DNAzymes, towards the goal of understanding the structural properties leading to metal ion specificity. Progress made and insight gained from a range of biochemical and biophysical techniques are covered, and promising directions for future investigations are discussed.
Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Kevin
K
Hwang
Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Parisa
P
Hosseinzadeh
Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Yi
Y
Lu
Metalloenzymes; catalytic DNA; deoxyribozymes; metal ion selectivity; metal sensors; metal-nucleic acid interactions
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