[Cushing syndrome in a HIV patient using inhaled steroids. Report of one case].
We report a 41-year-old man with HIV and a chronic obstructive pulmonary disease, treated for seven months with Fluticasone/Salmeterol and antiretroviral therapy (Lamivudine, Tenofovir, Atazanavir and Ritonavir). While using these medications, the patients developed a Cushing syndrome in a period of five months. After performing laboratory and imaging tests, it was concluded that the most probable cause of the syndrome was the interaction of inhaled steroids with Ritonavir. After discontinuing these medications the syndrome reverted in a period of 8 months.
Escuela de Postgrado, Facultad de Medicina, Universidad Católica del Maule, Talca, Chile, afriasoyarzun@gmail.com.
Alondra
A
Frías
Facultad de Medicina, Universidad Católica del Maule, Talca, Chile.
Alex
A
Ortiz
Facultad de Medicina, Universidad Católica del Maule, Talca, Chile.
Miriam
M
Soto
Servicio de Medicina, Hospital Regional de Talca, Talca, Chile.
Francisco
F
Muñoz
Servicio de Medicina, Hospital Regional de Talca, Talca, Chile.
Carolina
C
Chacón
D000328:Adult; D001993:Bronchodilator Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003480:Cushing Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D004347:Drug Interactions; D000068298:Fluticasone / Q000009:adverse effects* / Q000627:therapeutic use; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009330:Nebulizers and Vaporizers; D000068299:Salmeterol Xinafoate / Q000009:adverse effects* / Q000627:therapeutic use
D001993:Bronchodilator Agents; D017320:HIV Protease Inhibitors; D000068299:Salmeterol Xinafoate; D000068298:Fluticasone