Novel surgical techniques, regenerative medicine, tissue engineering and innovative immunosuppression in kidney transplantation.
On the 60thanniversary of the first successfully performed renal transplantation, we summarize the historical, current and potential future status of kidney transplantation. We discuss three different aspects with a potential significant influence on kidney transplantation progress: the development of surgical techniques, the influence of regenerative medicine and tissue engineering, and changes in immunosuppression. We evaluate the standard open surgical procedures with modern techniques and compare them to less invasive videoscopic as well as robotic techniques. The role of tissue engineering and regenerative medicine as a potential method for future kidney regeneration or replacement and the interesting search for novel solutions in the field of immunosuppression will be discussed. After 60 years since the first successfully performed kidney transplantation, we can conclude that the greatest achievements are associated with the development of surgical techniques and with planned systemic immunosuppression.
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; Chair of Surgical Oncology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Maciej
M
Nowacki
Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
Łukasz
Ł
Nazarewski
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Tomasz
T
Kloskowski
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Dominik
D
Tyloch
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Marta
M
Pokrywczyńska
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Katarzyna
K
Pietkun
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Arkadiusz
A
Jundziłł
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Janusz
J
Tyloch
Department of Geriatrics, Geriatric Research, Education, and Clinical Center, South Texas Veterans Healthcare System, San Antonio, TX, USA; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX, USA.
Samy L
SL
Habib
Chair of Urology, Department of Regenerative Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; Department of General and Oncological Urology, Nicolaus Copernicus Hospital, Torun, Poland.
Tomasz
T
Drewa
immunosuppression; kidney transplantation; novel surgical techniques; regenerative medicine; tissue engineering
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