Propofol-remifentanil is More Effective than Propofol-fentanyl in Decreasing Intraoperative Blood Loss during Sagittal Split Ramus Osteotomy.
This study retrospectively compared blood loss during sagittal split ramus osteotomy in patients receiving propofol-remifentanil (R group) and those receiving propofol-fentanyl (F group). All patients underwent sagittal split ramus osteotomy under general anesthesia during the 3-year 4-month period between October 2007 and February 2011 in an operating room at Tokyo Dental College Suidobashi Hospital. Blood loss in the R group was significantly less than that in the F group. Mean arterial pressure and heart rate, measured at 20 and 15 min after tracheal intubation, respectively, were both lower in the R group. No marked change was observed in blood pressure in the R group under general anesthesia, however. Volume of urine was also larger in the R group. The results of this study suggest that remifentanil is effective in reducing intraoperative blood loss during sagittal split ramus osteotomy.
Department of Dental Anesthesiology, Tokyo Dental College.
Toshiyuki
T
Handa
Takaaki
T
Onodera
Yoshifumi
Y
Honda
Yoshihiko
Y
Koukita
Tatsuya
T
Ichinohe
D000328:Adult; D000768:Anesthesia, General / Q000379:methods* / Q000706:statistics & numerical data*; D062186:Arterial Pressure / Q000187:drug effects; D016063:Blood Loss, Surgical / Q000517:prevention & control* / Q000706:statistics & numerical data; D005260:Female; D005283:Fentanyl / Q000627:therapeutic use*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D059229:Osteotomy, Sagittal Split Ramus / Q000009:adverse effects*; D010880:Piperidines / Q000627:therapeutic use*; D015742:Propofol / Q000627:therapeutic use; D000077208:Remifentanil; D012189:Retrospective Studies; D014041:Tokyo; D014556:Urine
D010880:Piperidines; D000077208:Remifentanil; D005283:Fentanyl; D015742:Propofol