An extremely rare case of prenatally diagnosed absent both aortic and pulmonary valves.
We describe a case of absent aortic and pulmonary valves, diagnosed at 16.4 weeks of gestation. Fetal echocardiography showed cardiomegaly with dilated both ventricles. No valve leaflets were observed in the aorta and pulmonary artery, and a typical to-and-fro flow pattern was noted in both great arteries on color Doppler imaging. Fetal hydrops was also detected. Follow-up ultrasonographic evaluation at 19 weeks demonstrated intrauterine fetal death. Postmortem autopsy revealed the absence of both aortic and pulmonary valve leaflets. To the best of our knowledge, this is the earliest diagnosed case of absent both aortic and pulmonary valves and only the second case to be diagnosed prenatally.
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hyeon Kyeong
HK
Yeon
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Mi-Young
0000-0003-2691-4954
MY
Lee
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Sun-Young
SY
Yoon
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hee Jung
HJ
Jung
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Ji Eun
JE
Park
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jae-Yoon
JY
Shim
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hye-Sung
HS
Won
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Pil-Ryang
PR
Lee
Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Ahm
A
Kim
Aortic valve; Congenital heart disease; Prenatal diagnosis; Pulmonary valve
Fetal Diagn Ther. 2015 ;38(4):307-14
25170850
J Am Coll Cardiol. 1994 May;23 (6):1452-8
8176106
Ultrasound Obstet Gynecol. 2013 Feb;41(2):162-7
22605612
Pediatr Cardiol. 1991 Apr;12(2):114-7
1866330
Heart. 1996 Jan;75(1):98-100
8624884
Heart Vessels. 1994;9(1):49-55
8113158