Electrophilic Fluorination of Secondary Phosphine Oxides and Its Application to P-O Bond Construction.
A novel and efficient electrophilic fluorination of secondary phosphine oxides with Selectfluor has been achieved. This transformation provides direct access to phosphoric fluorides in up to 92% yield under mild conditions. In addition, P-O bond construction via a one-pot coupling process of secondary phosphine oxides with water or alcohols in the presence of Selectfluor leads to the formation of phosphinic acids or phosphinates in up to 96% yield.
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Qian
Q
Chen
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Jiekun
J
Zeng
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Xinxing
X
Yan
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Yulin
Y
Huang
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Chunxiao
C
Wen
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Xingguo
X
Liu
School of Chemical Engineering and Light Industry, Guangdong University of Technology , Guangzhou, Guangdong 510006, China.
Kun
K
Zhang