Saint Ioannis Lampadistis, the first possible case of blindness due to organic mercury poisoning in history.
Saint Ioannis Lampadistis is a Cypriot saint of the Greek Orthodox Church, widely venerated in his island of origin. He lived during the 11th century and was blinded by ingesting contaminated fish in the mountainous area of Galata, withdrew from civil life when he was 18, and died at the age of 22. The reason for his blindness remains unknown, though it is widely attributed to an unknown poison related to the copper mines of the region. As fish is the end reservoir of organic mercury, it is quite possible that his blindness was the result of heavy metal toxicity. Organic mercury is associated with CNS atrophy and hypoplasia, and blindness is a frequent presenting symptom. While not much is known about the saint's clinical symptoms (as his ecclestiastical biography focuses on his example and miracles), organic mercury poisoning could explain his sudden loss of vision, thus possibly making him the first-recorded case of organic mercury poisoning in history.
1 Department of Optics and Optometry, Technical Education Institute of Athens, Aegaleo, Greece.|2 Department of Pediatric Ophthalmology, Euroclinic Children's Hospital, Athens, Greece.
Kleonikos A
KA
Tsakiris
D001766:Blindness / Q000209:etiology / Q000266:history*; D018612:Byzantium; D003535:Cyprus; D049691:History, Medieval; D006801:Humans; D008297:Male; D020262:Mercury Poisoning, Nervous System / Q000150:complications / Q000175:diagnosis / Q000266:history*; D018597:Saints; D055815:Young Adult
St Ioannis Lampadistis; blindness; organic mercury poisoning