[Association of waist-to-hip ratio with chronic kidney disease in non-diabetic subjects].
To explore the relationship between waist-to-hip ratio (WHR) and chronic kidney disease (CKD) in non-diabetic subjects and compare the difference between male and female subjects.



We performed a cross-sectional survey among 2142 community-based southern Chinese participants without diabetes from June to October 2012. We divided all the participants into 4 groups according to the gender-specific quartiles of WHR. Logistic regression models were used to explore the associations of WHR with CKD in these subjects.



In the unadjusted model, WHR was significantly associated with CKD in women (OR=7.29, 95% CI: 3.56-16.32, P<0.001), and the association was still significant (OR=6.13, 95% CI: 2.56-15.20, P=0.003 ) after adjustment for the potential confounders (including age, history of hypertension, coronary heart disease, current smoker, physical inactivity, education level, systolic blood pressure, diastolic blood pressure, serum triglyceride, serum high density lipoprotein, blood glucose, and BMI). The odds ratio (OR) for having CKD in the highest versus lowest quartile of WHR levels was 2.44 (95% CI: 0.98-4.97, P=0.103) in men in the unadjusted model.



WHR levels are associated with CKD in non-diabetic women but not in non-diabetic male subjects.
Department of Nephrology, Institute of Nephrology and Urology, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.E-mail: 15622190940@163.com.
Qin
Q
Zhou
Yong-Qiang
YQ
Li
Shuang-Shuang
SS
Zhu
Xin-Yu
XY
Liu
Xiao-Fei
XF
Shao
Bin
B
Li
Xiao-Hong
XH
Wang
Ying
Y
Zhang
Hong-Lei
HL
Wang
Jia-Min
JM
Li
Kang-Ping
KP
Deng
Qin
Q
Liu
He-Qun
HQ
Zou
D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity; D016017:Odds Ratio; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012307:Risk Factors; D049629:Waist-Hip Ratio