A combined self-assembly and calcination method for preparation of nanoparticles-assembled cobalt oxide nanosheets using graphene oxide as template and their application for non-enzymatic glucose biosensing.
Cobalt oxide (Co3O4)-based materials have been extensively investigated as efficient electrocatalysts for non-enzymatic glucose biosensing. The proper tuning the structure of Co3O4-based materials could improve sensing performances for glucose detection. Herein, we have developed a combined self-assembly and calcination method to prepare nanoparticles-assembled Co3O4nanosheets, which exhibit good sensing performances for glucose biosensing. The Co3O4nanosheets were prepared by the following three steps: (i) the Co2+modified graphene oxide (GO) was prepared by the self-assembly of Co2+and GO in aqueous solution firstly, and then Co2+modified GO film was obtained by vacuum filtration method; (ii) after calcination of Co2+modified GO film in N2atmosphere, Co3O4nanoparticles modified reduced GO (RGO) was obtained; (iii) finally, nanoparticles-assembled Co3O4nanosheets were obtained by calcination of Co3O4modified RGO in air to remove RGO template. Most importantly, Co3O4nanosheets exhibit good electrocatalytic activity for oxidation of glucose, leading to high-performance glucose sensor. The detection limit and linear range of Co3O4nanosheets-based glucose sensor in the present work are 0.15μM, and 1-50μM, respectively. Furthermore, such sensor also shows excellent selectivity for glucose detection, compared to the commonly interfering species including dopamine, and uric acid.
School of Materials Science and Engineering, Jilin University, Changchun 130012, PR China.
Haiyan
H
Zhang
College of Electronic Science and Engineering, Jilin University, Changchun 130012, PR China. Electronic address: liusen@jlu.edu.cn.
Sen
S
Liu
D015374:Biosensing Techniques; D001786:Blood Glucose / Q000032:analysis*; D003035:Cobalt / Q000737:chemistry*; D004298:Dopamine / Q000737:chemistry; D055664:Electrochemical Techniques; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*; D015203:Reproducibility of Results; D014527:Uric Acid / Q000737:chemistry
D001786:Blood Glucose; D010087:Oxides; D014527:Uric Acid; D003035:Cobalt; D006108:Graphite; C060728:cobalt oxide; D004298:Dopamine
Co(3)O(4) nanosheet; Glucose biosensing; Graphene oxide; Nanoparticles-assembled; Template