Alleviated negative rather than positive attentional bias in patients with depression in remission: an eye-tracking study.
Objective To investigate attentional bias toward happy and sad faces in remitted depressed (RD) patients compared with healthy control (HC) subjects. Methods This cross-sectional study enrolled RD patients and sex- and age-matched HC subjects. Eye movement data were acquired for all study participants while free viewing a 2 × 2 matrix of emotional faces. The attentional bias toward different emotional faces and whether the attention maintenance components generated attentional bias in the RD patients were analysed by comparing the attentional modes of the RD group with the HC group. Results A total of 27 RD patients and 27 HC subjects were analysed in this study. The RD and HC groups exhibited no significant differences toward first fixation location and initial attentional maintenance. In later attentional maintenance, the RD group showed significantly less attentional bias toward happy faces, but there were no significant differences in their attentional bias toward sad faces, compared with the HC group. Conclusions This present study showed that the negative attentional bias of RD patients was successfully eased, but their positive attentional bias was still insufficient.
1 The International Web Intelligence Consortium (WIC) Institute, Beijing University of Technology, Beijing, China.|2 The Beijing International Collaboration Base on Brain Informatics and Wisdom Services, Beijing, China.|3 The Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China.
Mi
M
Li
1 The International Web Intelligence Consortium (WIC) Institute, Beijing University of Technology, Beijing, China.|2 The Beijing International Collaboration Base on Brain Informatics and Wisdom Services, Beijing, China.|3 The Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China.
Shengfu
S
Lu
4 Mood Disorders Centre & China Clinical Research Centre for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.|5 Centre of Depression, Beijing Institute for Brain Disorders, Beijing, China.
Gang
G
Wang
4 Mood Disorders Centre & China Clinical Research Centre for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.|6 Beijing Key Laboratory for Mental Disorders, Beijing, China.
Lei
L
Feng
4 Mood Disorders Centre & China Clinical Research Centre for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Bingbing
B
Fu
1 The International Web Intelligence Consortium (WIC) Institute, Beijing University of Technology, Beijing, China.|2 The Beijing International Collaboration Base on Brain Informatics and Wisdom Services, Beijing, China.|3 The Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China.|7 Department of Life Science and Informatics, Maebashi Institute of Technology, Maebashi-City, Japan.
Ning
N
Zhong
D001288:Attention; D000070379:Attentional Bias / Q000502:physiology*; D003430:Cross-Sectional Studies; D003863:Depression / Q000523:psychology*; D003866:Depressive Disorder / Q000523:psychology*; D005133:Eye Movements; D005149:Facial Expression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
Remitted depression; attentional bias; emotion; eye tracking
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