Probable metronidazole induced serum sickness-like reaction in a paediatric patient.
OBJECTIVE
Metronidazole (MTZ) is a commonly prescribed antibiotic and is generally well tolerated. To our knowledge, there has been only one case report linking MTZ with serum sickness-like reaction (SSLR).


METHODS
We report a probable case of SSLR following the administration of MTZ in a paediatric patient.


CONCLUSIONS
Serum sickness-like reaction may be associated with MTZ therapy, and this type of adverse drug reaction may be underreported in the literature. A prior case report and evaluation with the Naranjo algorithm indicating a 'probable' adverse drug reaction provide evidence to support this conclusion.
The University of Tennessee Health Science Center, Memphis, TN, USA.|Le Bonheur Children's Hospital, Memphis, TN, USA.
H Z
HZ
VanCleave
The University of Tennessee Health Science Center, Memphis, TN, USA. alicia.sanchez@lebonheur.org.|Le Bonheur Children's Hospital, Memphis, TN, USA. alicia.sanchez@lebonheur.org.
A C
AC
Sanchez
The University of Tennessee Health Science Center, Memphis, TN, USA.|Le Bonheur Children's Hospital, Memphis, TN, USA.
J A
JA
Lieberman
The University of Tennessee Health Science Center, Memphis, TN, USA.|Le Bonheur Children's Hospital, Memphis, TN, USA.
J T
JT
Ellenburg
Le Bonheur Children's Hospital, Memphis, TN, USA.
W A
WA
Mabry
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000009:adverse effects*; D012713:Serum Sickness / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D008795:Metronidazole
metronidazole; paediatrics; serum sickness-like reaction