Metabolic Genes within Cyanophage Genomes: Implications for Diversity and Evolution.
Cyanophages, a group of viruses specifically infecting cyanobacteria, are genetically diverse and extensively abundant in water environments. As a result of selective pressure, cyanophages often acquire a range of metabolic genes from host genomes. The host-derived genes make a significant contribution to the ecological success of cyanophages. In this review, we summarize the host-derived metabolic genes, as well as their origin and roles in cyanophage evolution and important host metabolic pathways, such as the light-dependent reactions of photosynthesis, the pentose phosphate pathway, nutrient acquisition and nucleotide biosynthesis. We also discuss the suitability of the host-derived metabolic genes as potential diagnostic markers for the detection of genetic diversity of cyanophages in natural environments.
School of The Environment and Safety Engineering, Jiangsu University, No. 301, Xuefu Road, Zhenjiang 212013, Jiangsu Province, China. gaofei@ujs.edu.cn.
E-Bin
EB
Gao
Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, No. 164, Xingangxi Road, Haizhu District, Guangzhou 5103401, Guangdong Province, China. huangyh@scsio.ac.cn.
Youhua
Y
Huang
ACS Key Laboratory of Algae Biology, Institute of Hydrobiology, Chinese Academy of Sciences, No. 7, Donghu South Road, Wuchang District, Wuhan 430072, Hubei Province, China. ningdegang@ihb.ac.cn.
Degang
D
Ning
cyanobacteria; cyanophage; diagnostic marker; genetic diversity; metabolism
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