Exercise increases the level of plasma orexin A in humans.
BACKGROUND
The purpose of this research was to study the effects of exercise on the concentration of plasma orexin A, a peptide regulating several physiological functions.


METHODS
Blood samples were collected from participants (men, n=10; age: 24.4±2.93 years) 15, 0 min before the start of exercise, and 30, 45, 60 min after a cycle ergometer exercise at 75 W for 15 min. Also heart rate (HR), galvanic skin response (GSR), and rectal temperature were monitored.


RESULTS
The exercise induced a significant increase (p<0.01) in plasmatic orexin A with a peak at 30 min after the exercise bout, in association with an increase of the other three monitored variables: HR (p<0.01), GSR (p<0.05), and rectal temperature (p<0.01).


CONCLUSIONS
Our findings indicate that plasmatic orexin A is involved in the reaction to physical activity.
Giovanni
G
Messina
Giovanni
G
Di Bernardo
Andrea
A
Viggiano
Vincenzo
V
De Luca
Vincenzo
V
Monda
Antonietta
A
Messina
Sergio
S
Chieffi
Umberto
U
Galderisi
Marcellino
M
Monda
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001831:Body Temperature / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test / Q000379:methods; D005334:Fever / Q000097:blood; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D000068797:Orexins / Q000097:blood*; D055815:Young Adult
D015415:Biomarkers; D000068797:Orexins