Design of Self-Assembling Protein-Polymer Conjugates.
Protein-polymer conjugates are of particular interest for nanobiotechnology applications because of the various and complementary roles that each component may play in composite hybrid-materials. This chapter focuses on the design principles and applications of self-assembling protein-polymer conjugate materials. We address the general design methodology, from both synthetic and genetic perspective, conjugation strategies, protein vs. polymer driven self-assembly and finally, emerging applications for conjugate materials. By marrying proteins and polymers into conjugated bio-hybrid materials, materials scientists, chemists, and biologists alike, have at their fingertips a vast toolkit for material design. These inherently hierarchical structures give rise to useful patterning, mechanical and transport properties that may help realize new, more efficient materials for energy generation, catalysis, nanorobots, etc.
Department of Chemistry (0212), 900 West Campus Drive, Blacksburg, VA, 24061, USA.
Nathan A
NA
Carter
Department of Chemistry (0212), 900 West Campus Drive, Blacksburg, VA, 24061, USA.
Xi
X
Geng
Department of Chemistry (0212), 900 West Campus Drive, Blacksburg, VA, 24061, USA. tijana.grove@vt.edu.
Tijana Z
TZ
Grove
D053761:Nanocomposites / Q000737:chemistry*; D015202:Protein Engineering / Q000379:methods*; D011506:Proteins / Q000737:chemistry* / Q000235:genetics
D011506:Proteins
Bio-hybrid materials; Conjugation strategies; Molecular-scale interactions; Nanostructural design; Protein-polymer conjugates; Self-assembly