Congenital pulmonary airway malformation (CPAM) with initial presentation in an adult: a rare presentation of a rare disease.
Congenital pulmonary airway malformation (CPAM) is a rare congenital abnormality with unknown exact aetiology or clear genetic association. It is characterised by a failure of bronchial development and localised glandular overgrowth. Typically, it is diagnosed on prenatal ultrasound, only infrequently in children, and even less commonly in adults. We present a case of a 25-year-old man, with no previous lung diseases who presented with right-sided chest pain, fever and cough suggestive of pulmonary infection. Chest imaging, including CT scan, showed a large focal cystic mass within the right lower lobe along with ground glass opacities suggestive of CPAM. He was started on intravenous antibiotics. Bronchoscopy showed a large amount of pus in the right lung and bronchoalveolar lavage confirmed the microbiological diagnosis of methicillin-resistant Staphylococcus aureus. He improved with antibiotic treatment. He was discharged with 6-week course of antibiotics and follow-up afterward.
University of Missouri-Kansas City, Pulmonary/Critical Care, Kansas City, Missouri, USA.
Mohannad
M
Abu Omar
Department of Internal medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.
Emily
E
Tylski
Department of Internal medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.
Mouhanna
M
Abu Ghanimeh
University of Missouri-Kansas City, Pulmonary/Critical Care, Kansas City, Missouri, USA.
Ashraf
A
Gohar
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D018893:Bronchoalveolar Lavage / Q000379:methods; D001999:Bronchoscopy / Q000379:methods*; D002981:Clindamycin / Q000008:administration & dosage*; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D057915:Drug Substitution / Q000379:methods; D006801:Humans; D008168:Lung / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000382:microbiology; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification; D011023:Pneumonia, Staphylococcal / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D035583:Rare Diseases; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D014640:Vancomycin / Q000008:administration & dosage / Q000009:adverse effects
D000900:Anti-Bacterial Agents; D002981:Clindamycin; D014640:Vancomycin
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