Magnetic silica nanocomposites for magnetic hyperthermia applications.
This article summarises nearly all magnetic silica nanocomposites that have been synthesised for biomedical applications and evaluated under alternating magnetic field (AMF) from the point of view of heat generation. The use of these nanocomposites as a drug delivery system for remote control of drug release via applying AMF is described. Different parameters that affect the magnetic properties and, therefore, affect the amount of generated heat and the fact that sometimes these parameters are in conflict with each other are discussed. This review article presents insight into the synthesis of nanocomposites with optimal characteristics and use of them in optimal conditions to achieve the optimal magnetic properties for magnetic hyperthermia.
a Nanotechnology Research Center, School of Pharmacy , Mashhad University of Medical Sciences , Mashhad , Iran.
Legha
L
Ansari
a Nanotechnology Research Center, School of Pharmacy , Mashhad University of Medical Sciences , Mashhad , Iran.
Bizhan
B
Malaekeh-Nikouei
Drug delivery; hyperthermia; magnetic nanoparticles; nanocomposites; silica