Nonalcoholic fatty liver disease, association with cardiovascular disease and treatment. (I). Nonalcoholic fatty liver disease and its association with cardiovascular disease.
Non-alcoholic fatty liver disease (NAFLD) comprises a series of histologically lesions similar to those induced by alcohol consumption in people with very little or no liver damage. The importance of NAFLD is its high prevalence in the Western world and, from the point of view of the liver, in its gradual progression from steatosis to steatohepatitis, cirrhosis, and liver cancer. During the last decade it has been observed that NAFLD leads to an increased cardiovascular risk with acceleration of arteriosclerosis and events related to it, being the main cause of its morbidity and mortality. This review, updated to January 2016, consists of two parts, with the first part analysing the association of NAFLD with cardiovascular disease.
Unidad de Lípidos, Servicio de Medicina Interna, Hospital San Pedro, Logroño, España. Electronic address: abrea@riojasalud.es.
Ángel
Á
Brea
Unidad de Lípidos y Riesgo Vascular, Servicio de Medicina Interna, Hospital Universitario de Bellvitge, Idibell. CiberObn, L'Hospitalet de Llobregat, Barcelona, España.
Xavier
X
Pintó
Servicio de Endocrinología, Hospital Clínico , Valencia, España.
Juan F
JF
Ascaso
Atención Primaria, Área Sanitaria de Delicias, Zaragoza, España.
Mariano
M
Blasco
Centro de Salud de Bembibre, Bembibre, León, España.
Ángel
Á
Díaz
Departamento de Medicina, Universidad de Málaga.
Pedro
P
González-Santos
Servicio de Endocrinología, Hospital Universitario Dr. Peset, Universitat de València , Valencia, España.
Antonio
A
Hernández Mijares
Atención Primaria, Centro de Salud de Prosperidad, Madrid, España.
Teresa
T
Mantilla
Unidad de Lípidos, Servicio de Medicina Interna, Hospital General Universitario Gregorio Marañón, Universidad Complutense , Madrid, España.
Jesús
J
Millán
Unidad de Lípidos y Riesgo Vascular, Servicio de Endocrinología y Nutrición, Hospital del Mar, Universitat Autònoma de Barcelona , Barcelona, España.
Juan
J
Pedro-Botet
D050197:Atherosclerosis / Q000209:etiology* / Q000401:mortality; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000401:mortality; D018450:Disease Progression; D006801:Humans; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications* / Q000401:mortality / Q000503:physiopathology; D012307:Risk Factors
Arteriosclerosis; Atherosclerosis; Cardiovascular diseases; Cardiovascular risk; Enfermedad del hígado graso no alcohólica; Enfermedades cardiovasculares; Esteatohepatitis no alcohólica; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Riesgo cardiovascular; Tratamiento; Treatment