11C- or 18F-Choline PET/CT for Imaging Evaluation of Biochemical Recurrence of Prostate Cancer.
Recurrence of prostate cancer is suspected when an increase in the prostate-specific antigen level is detected after radical treatment; the recurrence could be local relapse, distant relapse, or both. Differentiation between the two patterns of relapse is critical for choosing the proper treatment strategy. Choline PET/CT could be of help in discriminating patients with local, lymph node, and bone recurrences, thus having an impact on patient management.
Unit of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy; and.
Paola
P
Mapelli
Unit of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy; and.
Elena
E
Incerti
Unit of Nuclear Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Francesco
F
Ceci
Unit of Nuclear Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Paolo
P
Castellucci
Unit of Nuclear Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Stefano
S
Fanti
Unit of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy; and picchio.maria@hsr.it.
Maria
M
Picchio
D002794:Choline / Q000031:analogs & derivatives*; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000473:pathology / Q000517:prevention & control; D017063:Outcome Assessment, Health Care / Q000379:methods; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy*; D019275:Radiopharmaceuticals; D016896:Treatment Outcome
D019275:Radiopharmaceuticals; C516370:fluoromethylcholine; C447081:methyl carbon-11 choline; D002794:Choline
11C-choline; 18F-choline; PET/CT; biochemical recurrence; prostate cancer