Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology.
Purpose. To compare the ocular surface symptoms and signs in an adult population of silicone-hydrogel (Si-Hy) contact lens (CL) wearers with another modality of CL wear, overnight orthokeratology (OK).Materials and Methods. This was a prospective and comparative study in which 31 myopic subjects were fitted with the same Si-Hy CL and 23 underwent OK treatment for 3 months. Dry eye questionnaire (DEQ) was filled in at the beginning of the study and then after 15 days, 1 month, and 3 months using each CL modality. The tear quality was evaluated with noninvasive tear break-up time. Tear production was measured with Schirmer test. Tear samples were collected with Schirmer strips being frozen to analyze the dinucleotide diadenosine tetraphosphate (Ap4A) concentration with High-Performance Liquid Chromatography (HPLC).Results. After refitting with ortho-k, a reduction in discomfort and dryness symptoms at the end of the day (p< 0.05,χ2) was observed. No significant changes were observed in Ap4A concentration in any group. Bulbar redness, limbal redness, and conjunctival staining increased significantly in the Si-Hy group (p< 0.05, Kruskal-Wallis test).Conclusion. Discomfort and dryness symptoms at the end of the day are lower in the OK CL group than in the Si-Hy CL group.
Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics (Optometry), School of Sciences, University of Minho, Gualtar, 4710-057 Braga, Portugal; Ocular Surface and Contact Lenses Research Group, University of Santiago de Compostela, Santiago de Compostela, 15782 A Coruña, Spain.
Nery
0000-0002-1341-1592
N
García-Porta
Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics (Optometry), School of Sciences, University of Minho, Gualtar, 4710-057 Braga, Portugal.
Laura
L
Rico-Del-Viejo
Department of Optics II (Optometry and Vision), School of Optics, Universidad Complutense de Madrid, Madrid, Spain.
Alba
A
Martin-Gil
Department of Optics II (Optometry and Vision), School of Optics, Universidad Complutense de Madrid, Madrid, Spain.
Gonzalo
0000-0003-0054-1731
G
Carracedo
Department of Optics II (Optometry and Vision), School of Optics, Universidad Complutense de Madrid, Madrid, Spain.
Jesus
0000-0002-9191-7679
J
Pintor
Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics (Optometry), School of Sciences, University of Minho, Gualtar, 4710-057 Braga, Portugal.
José Manuel
0000-0001-9050-4170
JM
González-Méijome
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