ME-CAGEBIRDr,X-CPMG-HSQMBC. A phase sensitive, multiplicity edited long range HSQC with absorptive line shapes.
ME-CAGEBIRDr,X-CPMG-HSMBC pulse sequence is a phase sensitive, carbon multiplicity edited 2D-experiment for detecting heteronuclear correlations originating from long-range1H,13C-couplings,nJCH. The presented method allows measurement ofnJCH-values as well as is capable of separating different carbon types in subspectra (13C/13CH2and13CH/13CH3) with minimal amount of cross talk i.e. cross peaks from wrong carbon multiplicity. Pure lineshapes and clean subspectra are achieved by utilizing CPMG in polarization transfer period, CRISIS-approach in multiplicity editing period and zero-quantum filtration. The obtained spectral properties together with simple setup of the experiment make ME-CAGEBIRDr,X-CPMG-HSMBC a useful addition into synthetic organic chemistry oriented NMR-tool collection.
VERIFIN, Department of Chemistry, University of Helsinki, P.O. Box 55, FIN-00014 Helsinki, Finland.
Harri
H
Koskela
Department of Chemistry, University of Helsinki, P.O. Box 55, FIN-00014 Helsinki, Finland.
Ilkka
I
Kilpeläinen
Department of Chemistry, University of Helsinki, P.O. Box 55, FIN-00014 Helsinki, Finland. Electronic address: Sami.Heikkinen@helsinki.fi.
Sami
S
Heikkinen
CPMG; CRISIS; Carbon multiplicity edition; HSQMBC; Long-range coupling constants