Cost-benefit of appointment-based medication synchronization in community pharmacies.
OBJECTIVE
To evaluate the cost-benefit of appointment-based medication synchronization (ABMS) offered in community pharmacies for patients taking chronic medications to prevent negative outcomes associated with hyperlipidemia, hypertension, and diabetes.


METHODS
Decision-tree analysis based on published literature and publicly available data.


METHODS
Program benefits were based on linking published findings of improvements in medication adherence due to the implementation of an ABMS program to a claims-based study of disease-related medical costs associated with different levels of adherence. The direct cost of the program-increased medication utilization as a result of improved adherence-was calculated from publicly available prescription pricing data. Benefit-cost ratios were assessed from a payer perspective over a 1-year time frame.


RESULTS
Additional medication expenditures due to improved adherence associated with ABMS enrollment were offset by lower disease-specific medical costs. Medical savings per additional dollar spent on medications ranged from approximately $1 to $37 depending on the medication and medication class considered. ABMS was most cost-beneficial for metformin and statins. Sensitivity analyses showed that cost-benefit was significantly impacted by medication costs and any service fees associated with ABMS.


CONCLUSIONS
ABMS programs have been shown to increase medication adherence in patients taking chronic medications. These programs were shown to have a significant cost-benefit for healthcare payers by reducing medical utilization and costs. Payers should consider supporting the provision of these programs in community pharmacies.
Julie A
JA
Patterson
Virginia Commonwealth University School of Pharmacy, Department of Pharmacotherapy and Outcomes Sciences, McGuire Hall, Room 213, PO Box 980533, 1112 East Clay St, Richmond, VA 23298-0533. E-mail: daholdfo@vcu.edu.
David A
DA
Holdford
Kunai
K
Saxena
D003157:Community Pharmacy Services; D003362:Cost-Benefit Analysis; D003663:Decision Trees; D006801:Humans; D055118:Medication Adherence; D059065:Medication Reconciliation / Q000191:economics*; D014481:United States