SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES.
Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections.
Universidade Federal do Ceará-UFC, Departamento de Química Analítica e Físico-Química Grupo de Química de Materiais Avançados(GQMAT). Campus do Pici, CP 12100, 60451-970 Fortaleza, CE, Brazil. E-mails: afraniocunha7@gmail.com; maome@superig.com.br; aubersonfarmaufc@gmail.com; pbafechine@gmail.com.|Universidade Federal do Ceará-UFC, Departamento de Análises Clínicas, Laboratório de Microbiologia de Leveduras. Fortaleza, CE, Brazil. E-mails: afraniocunha70@gmail.com; cecinhya@gmail.com; aubersonfarmaufc@gmail.com; microufc@gmail.com; iedaufc@gmail.com; menezes@ufc.br.
Francisco Afrânio
FA
Cunha
Universidade Federal do Ceará-UFC, Departamento de Análises Clínicas, Laboratório de Microbiologia de Leveduras. Fortaleza, CE, Brazil. E-mails: afraniocunha70@gmail.com; cecinhya@gmail.com; aubersonfarmaufc@gmail.com; microufc@gmail.com; iedaufc@gmail.com; menezes@ufc.br.
Kamila Rocha
KR
Maia
Universidade Federal do Ceará-UFC, Departamento de Química Analítica e Físico-Química Grupo de Química de Materiais Avançados(GQMAT). Campus do Pici, CP 12100, 60451-970 Fortaleza, CE, Brazil. E-mails: afraniocunha7@gmail.com; maome@superig.com.br; aubersonfarmaufc@gmail.com; pbafechine@gmail.com.
Eduardo José Jucá
EJ
Mallman
Universidade Federal do Ceará-UFC, Departamento de Análises Clínicas, Laboratório de Microbiologia de Leveduras. Fortaleza, CE, Brazil. E-mails: afraniocunha70@gmail.com; cecinhya@gmail.com; aubersonfarmaufc@gmail.com; microufc@gmail.com; iedaufc@gmail.com; menezes@ufc.br.
Maria da Conceição Dos Santos Oliveira
MD
Cunha
Universidade Federal do Ceará-UFC, Departamento de Análises Clínicas, Laboratório de Microbiologia de Leveduras. Fortaleza, CE, Brazil. E-mails: afraniocunha70@gmail.com; cecinhya@gmail.com; aubersonfarmaufc@gmail.com; microufc@gmail.com; iedaufc@gmail.com; menezes@ufc.br.
Antonio Auberson Martins
AA
Maciel
Universidade Federal do Ceará-UFC, Departamento de Análises Clínicas, Laboratório de Microbiologia de Leveduras. Fortaleza, CE, Brazil. E-mails: afraniocunha70@gmail.com; cecinhya@gmail.com; aubersonfarmaufc@gmail.com; microufc@gmail.com; iedaufc@gmail.com; menezes@ufc.br.
Ieda Pereira de
IP
Souza
Universidade Federal do Ceará-UFC, Departamento de Análises Clínicas, Laboratório de Microbiologia de Leveduras. Fortaleza, CE, Brazil. E-mails: afraniocunha70@gmail.com; cecinhya@gmail.com; aubersonfarmaufc@gmail.com; microufc@gmail.com; iedaufc@gmail.com; menezes@ufc.br.
Everardo Albuquerque
EA
Menezes
Universidade Federal do Ceará-UFC, Departamento de Química Analítica e Físico-Química Grupo de Química de Materiais Avançados(GQMAT). Campus do Pici, CP 12100, 60451-970 Fortaleza, CE, Brazil. E-mails: afraniocunha7@gmail.com; maome@superig.com.br; aubersonfarmaufc@gmail.com; pbafechine@gmail.com.
Pierre Basílio Almeida
PB
Fechine
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