Borane-Catalyzed Transfer Hydrogenations of Pyridines with Ammonia Borane.
With the use of ammonia borane as a hydrogen source, a borane catalyzed metal-free transfer hydrogenation of pyridines was successfully realized for the first time to furnish a variety of piperidines in 44-88% yields with moderate to excellent cis-selectivities. The ease in handling without requiring high pressure H2makes this transfer hydrogenation practical and useful.
State Key Laboratory of Chemical Resource, Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology , Beijing 100029, China.
Qiwen
Q
Zhou
State Key Laboratory of Chemical Resource, Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology , Beijing 100029, China.
Lanqiong
L
Zhang
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|University of Chinese Academy of Sciences , Beijing 100049, China.
Wei
W
Meng
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|University of Chinese Academy of Sciences , Beijing 100049, China.
Xiangqing
X
Feng
State Key Laboratory of Chemical Resource, Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology , Beijing 100029, China.
Jing
J
Yang
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|University of Chinese Academy of Sciences , Beijing 100049, China.
Haifeng
H
Du