Hemodynamic Study of Three Patterns of Flaps on Rats with a Novel Panoramic Photographing Technique Involved.
BACKGROUND
No study heretofore has been conducted to investigate the hemodynamic characteristics of the perforator, perforator-plus, and random flaps on an animal model.


METHODS
Thirty Sprague-Dawley rats were equally divided into three groups: the perforator group, the perforator-plus group, and the random group. Laser Doppler flowmetry was adopted for measurement of blood perfusion of the flaps at six time points. Another nine rats were equally divided into three groups and underwent the corresponding surgery. On day 7, the flaps were photographed for calculation of the necrosis rate. The vascular network of flaps in each group was photographed immediately postoperatively and at days 3 and 7 after surgery with a special technique first proposed by us.


RESULTS
No significant difference in flap necrosis could be detected in the perforator and perforator-plus flaps. Other than on day 1, when perfusion of the perforator was significantly stronger than that of the perforator-plus flap, there was no significant difference between the perforator and perforator-plus flaps. The three perforasomes in the perforator and perforator-plus flaps could all survive because of considerable dilation of vessels. On day 7, the vascular network between the iliolumbar perforator and the sacrococcygeal perforators underwent tremendous enlargement in diameter in the random flap group.


CONCLUSIONS
The perforator flap and the perforator-plus flap are equal in blood perfusion. The survival of the random flap depends on the dilation of the vascular network between the pedicle and the nearest potential perforator.
Fujian and Fuzhou, People's Republic of China.|From the Anatomic Department and the Orthopedic Department, First Affiliated Hospital, Fujian Medical University; and the Anatomical Institution, Department of Orthopedics, General Hospital of People's Liberation Army Nanjing District.
Yuehong
Y
Zhuang
Fujian and Fuzhou, People's Republic of China.|From the Anatomic Department and the Orthopedic Department, First Affiliated Hospital, Fujian Medical University; and the Anatomical Institution, Department of Orthopedics, General Hospital of People's Liberation Army Nanjing District.
Yun
Y
Xie
Fujian and Fuzhou, People's Republic of China.|From the Anatomic Department and the Orthopedic Department, First Affiliated Hospital, Fujian Medical University; and the Anatomical Institution, Department of Orthopedics, General Hospital of People's Liberation Army Nanjing District.
Zhihai
Z
Wu
Fujian and Fuzhou, People's Republic of China.|From the Anatomic Department and the Orthopedic Department, First Affiliated Hospital, Fujian Medical University; and the Anatomical Institution, Department of Orthopedics, General Hospital of People's Liberation Army Nanjing District.
Lan
L
Xue
Fujian and Fuzhou, People's Republic of China.|From the Anatomic Department and the Orthopedic Department, First Affiliated Hospital, Fujian Medical University; and the Anatomical Institution, Department of Orthopedics, General Hospital of People's Liberation Army Nanjing District.
Yingying
Y
Tang
Fujian and Fuzhou, People's Republic of China.|From the Anatomic Department and the Orthopedic Department, First Affiliated Hospital, Fujian Medical University; and the Anatomical Institution, Department of Orthopedics, General Hospital of People's Liberation Army Nanjing District.
Heping
H
Zheng
Fujian and Fuzhou, People's Republic of China.|From the Anatomic Department and the Orthopedic Department, First Affiliated Hospital, Fujian Medical University; and the Anatomical Institution, Department of Orthopedics, General Hospital of People's Liberation Army Nanjing District.
Fang
F
Fang
D000818:Animals; D006439:Hemodynamics; D017078:Laser-Doppler Flowmetry; D008297:Male; D009336:Necrosis; D010781:Photography / Q000379:methods*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013524:Surgical Flaps / Q000098:blood supply* / Q000473:pathology / Q000601:surgery
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