Palladium-Catalyzed Decarbonylative Cross-Coupling of Azinecarboxylates with Arylboronic Acids.
The first palladium-catalyzed decarbonylative coupling of phenyl 2-azinecarboxylates and arylboronic acids is presented. The key for the development of this decarbonylative coupling is the use of Pd/dcype as a catalyst. A wide range of 2-azinecarboxylates can undergo the present coupling reaction to afford 2-arylazines. By combination with previously reported nickel-catalyzed decarbonylative coupling, we achieved a chemoselective sequential decarbonylative coupling of pyridine dicarboxylate to synthesize 2,4-diarylpyridine.
Department of Applied Chemistry, Waseda University , 3-4-1 Ohkubo, Shinjuku, Tokyo169-8555, Japan.
Kei
K
Muto
Central Research Laboratory Technology and Development Division, Kanto Chemicals Co., Inc., Saitama 340-0003, Japan.
Taito
T
Hatakeyama
Kenichiro
K
Itami
Department of Applied Chemistry, Waseda University , 3-4-1 Ohkubo, Shinjuku, Tokyo169-8555, Japan.
Junichiro
J
Yamaguchi