Prevalence of Enterococcus faecalis mediated UTI and its current antimicrobial susceptibility pattern in Lahore, Pakistan.
To determine the prevalence of Enterococcus faecalis and recent trends in antimicrobial sensitivity profiling.



The study was conducted at Chughtais Lahore Lab, Lahore, Pakistan, from December 2013 to May 2014, and comprised urine specimens from suspected patients. Antimicrobial profiling of isolated strains of Enterococcus faecalis was determined by Kirby-Bauer disc-diffusion method.



Of the230 specimens, 161(70%) were positive for Enterococcus faecalis. The prevalence of Enterococcus faecalis-mediated urinary tract infections was 120(74.53%) in females and 41(25.46%) in males. Age-wise distribution of urinary tract infections among female patients was 41(34.16%) in >65 years age group. In males, the prevalence in the same age group was 19(46.34%). Besides, 145(90.09%) strains of Enterococcus faecalis exhibited resistance to gentamicin, 140(86.95%) to norfloxacin. Moreover, 138(85.71%) strains exhibited multi-drug resistance.



An overall pattern of drug resistance infections was observed in a majority of isolates.
Depatment of Microbiology and Molecular Genetics, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan.
Abid
A
Hussain
Depatment of Microbiology and Molecular Genetics, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan.
Muhammad
M
Sohail
Depatment of Microbiology and Molecular Genetics, University of the Punjab, Quaid-e-Azam Campus, Lahore, Pakistan.
Zaigham
Z
Abbas
D000368:Aged; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D013293:Enterococcus faecalis / Q000302:isolation & purification / Q000472:pathogenicity*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010154:Pakistan; D015995:Prevalence; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents
 Urinary tract infection, Enterococcus faecalis, Antimicrobial susceptibility.