Left Ventricular Apical Aneurysm in a Cat With Primary Cardiomyopathy.
A 13-year-old female Persian cat died suddenly after severe respiratory distress. At necropsy, the changes were compatible with congestive heart failure. The heart was enlarged with a flabby and puckered sac-like aneurysm at the apex of the left ventricle. The apical zone showed a thin muscular wall arising from the free wall of the left ventricle connected to a bulged saccular area through a wide communication. Microscopically, the wall of the aneurysm was composed of fibrous connective tissue with neovascularization and sparse atrophied myocardial cells at the margins. A few isolated cardiomyocytes in the lesion stained positively for desmin, and the inner lining of the aneurysm had immunoreactivity to von Willebrand factor and CD31. Mature fibrous connective tissue was interspersed with degenerated and disorganized cardiomyocytes elsewhere in the myocardium, and many small myocardial arteries were tortuous and thickened. In this case of sudden death, the diagnosis was primary cardiomyopathy, with formation of a left ventricular apical aneurysm within an area of marked myocardial fibrosis and cardiomyocyte atrophy.
1 Posgrado Conjunto Agronomía-Veterinaria, Universidad Autónoma de Nuevo León, Ex-Hacienda el Canadá, Gral. Escobedo, N.L. México.
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Ramírez-Hernández
2 Hospital San José-Tecnológico de Monterrey, Laboratorio de Patología, Monterrey, N.L., México.
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Barbosa-Quintana
1 Posgrado Conjunto Agronomía-Veterinaria, Universidad Autónoma de Nuevo León, Ex-Hacienda el Canadá, Gral. Escobedo, N.L. México.
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Ramírez-Romero
D000818:Animals; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D017809:Fatal Outcome; D005260:Female; D006322:Heart Aneurysm / Q000473:pathology / Q000662:veterinary*; D006352:Heart Ventricles / Q000473:pathology*
apical aneurysm; cardiomyopathy; cats; diverticulum; heart failure; left ventricle