Shedding Light on Shingles: The Power of Prevention.
Shingles, or herpes zoster (HZ), is a common secondary infection caused by a reactivated varicella zoster virus (VZV). More than 95% of immunocompetent individuals aged at least 50 years are seropositive for VZV and are therefore at risk for developing HZ. Age-related increased incidence of HZ and its complications are thought to be related to the decline in cell-mediated immunity. Complications of HZ, which create a significant patient and economic burden, may be neurological, ophthalmological, dermatological, or visceral. HZ vaccination is essential for the prevention of HZ and its consequences. This CME activity reviews the clinical presentations and complications of HZ as well as discusses strategies for prevention (Online access: http://courses.elseviercme.com/shingles/626).
Dean and Professor, Physician Assistant Studies Gardner-Webb University, College of Health Sciences, Boiling Springs, North Carolina.
Lawrence
L
Herman
Professor of Pediatrics and Medicine, University of Colorado School of Medicine, Aurora.
Myron J
MJ
Levin
Vice Chair, Department of Infectious Disease, Cleveland Clinic, Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Ohio.
Susan
S
Rehm
D000367:Age Factors; D006562:Herpes Zoster / Q000175:diagnosis* / Q000276:immunology / Q000517:prevention & control; D053061:Herpes Zoster Vaccine / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology
D053061:Herpes Zoster Vaccine