Factors influencing time to case registration for youth with type 1 and type 2 diabetes: SEARCH for Diabetes in Youth Study.
The development of a sustainable pediatric diabetes surveillance system for the United States requires a better understanding of issues related to case ascertainment.



Using the SEARCH for Diabetes in Youth registry, we examined whether time from diabetes diagnosis to case registration differed by diabetes type, patient demographics, and the type of provider reporting the case to the study. Plots for time from diagnosis to registration were developed, and differences by key variables were examined using the log-rank test.



Compared with time to registration for type 1 cases, it took 2.6 (95% confidence interval [CI], 2.5-2.6) times longer to register 50% of type 2 diabetes cases, and 2.3 (95% CI, 2.0-2.5) times longer to register 90% of type 2 cases. For type 1 diabetes cases, a longer time to registration was associated with older age, minority race/ethnicity, and cases, where the referring provider was not an endocrinologist. For type 2 diabetes cases, older age, non-Hispanic white race/ethnicity, and cases reported by providers other than an endocrinologist took longer to identify and register.



These findings highlight the need for continued childhood diabetes surveillance to identify future trends and influences on changes in prevalence and incidence.
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora. Electronic address: Tessa.Crume@ucdenver.edu.
Tessa L
TL
Crume
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora.
Richard F
RF
Hamman
Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC.
Scott
S
Isom
Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC.
Jennifer
J
Talton
Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC.
Jasmin
J
Divers
School of Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill.
Elizabeth J
EJ
Mayer-Davis
School of Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill.
Victor W
VW
Zhong
Department of Epidemiology and Biostatistics, University of South Carolina, Columbia.
Angela D
AD
Liese
Division of Diabetes Translation, Centers for Disease Control and Prevention, Hyattsville, MD.
Sharon
S
Saydah
Division of Endocrinology, Children's Hospital Medical Center, Cincinnati, OH.
Debra A
DA
Standiford
Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena.
Jean M
JM
Lawrence
Department of Pediatric Endocrinology, Children's Hospital & Regional Medical Center, University of Washington, Seattle.
Catherine
C
Pihoker
Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora.
Dana
D
Dabelea
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000453:epidemiology*; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D020380:Needs Assessment; D015995:Prevalence; D044469:Racial Groups / Q000706:statistics & numerical data*; D012042:Registries; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors; D018709:Statistics, Nonparametric; D014481:United States / Q000453:epidemiology; D055815:Young Adult
Case ascertainment; Diabetes in youth; Surveillance; Type 1 diabetes; Type 2 diabetes
J Clin Endocrinol Metab. 2011 Jan;96(1):159-67
20962021
Diabetologia. 1998 Aug;41(8):904-10
9726592
J Pediatr. 1996 May;128(5 Pt 1):608-15
8627431
Am J Epidemiol. 2013 Oct 1;178(7):1106-13
23887044
Diabetes Care. 2011 Jul;34(7):1628-33
21636800
J Pediatr Endocrinol Metab. 2007 Oct;20(10):1093-107
18051928
Int J Circumpolar Health. 2012 May 07;71(0):1-7
22584517
Control Clin Trials. 2004 Oct;25(5):458-71
15465616
JAMA. 2014 May 7;311(17):1778-86
24794371
Diabetes Care. 1998 Aug;21(8):1278-81
9702433
Diabet Med. 2013 Feb;30(2):170-8
23075321
JAMA. 2007 Jun 27;297(24):2765-6
17595280