Challenges in visceral leishmaniasis control and elimination in the developing countries: A review.
Leishmaniasis is a disease caused by an obligate intracellular protozoan that affects animals and human. Transmission is zoonotic and/or anthroponotic through the bite of an infected female sandfly. Control and elimination of visceral leishmaniasis (VL) require proper case detection, identification of reservoir hosts, and launching of effective vector control strategies in endemic areas. The aim of this review was to highlight the challenges in VL control in developing countries. Literatures pertaining to VL burden, diagnosis, prevention and control from the year 1969 to 2014 were systematically reviewed from PubMed, Scopus, Medline and Google scholar sources during July 2015. Poor vector control strategies, limited diagnostic services, drugs, treatments and lack of community awareness are the most important challenges in VL control and elimination especially in endemic areas. Absence of highly sensitive and specific tests, lack of trained man power, and community awareness are the major challenges in VL control. Therefore, proper case diagnosis, community mobilization and launching of effective vector control strategies in endemic areas are vital.
Department of Microbiology, Immunology and Parasitology, College of Medicine and Health Science, Bahir Dar University, Ethiopia.
Tadesse
T
Hailu
Department of Microbiology, Immunology and Parasitology, College of Medicine and Health Science, Bahir Dar University, Ethiopia.
Mulat
M
Yimer
Department of Microbiology, Immunology and Parasitology, College of Medicine and Health Science, Bahir Dar University, Ethiopia.
Wondemagegn
W
Mulu
Department of Microbiology, Immunology and Parasitology, College of Medicine and Health Science, Bahir Dar University, Ethiopia.
Bayeh
B
Abera
D003140:Communicable Disease Control / Q000379:methods* / Q000458:organization & administration*; D003906:Developing Countries; D003955:Diagnostic Tests, Routine / Q000379:methods; D060740:Disease Eradication / Q000379:methods* / Q000458:organization & administration*; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*