Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements.
Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is increasingly common. Novel tools for genetic manipulation of vectors, use of Wolbachia endosymbiotic bacteria, and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies, adding to strong interest in vector biology and genetics as well as vector-pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructure investment should be informed by the research community. A survey initiated by the European Horizon 2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key activities that are needed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such activities to be carried out. We summarize the most important findings of the survey which in particular reflect the priorities of researchers in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations.
a MRC-University of Glasgow Centre for Virus Research , Glasgow , UK.
Alain
A
Kohl
a MRC-University of Glasgow Centre for Virus Research , Glasgow , UK.
Emilie
E
Pondeville
a MRC-University of Glasgow Centre for Virus Research , Glasgow , UK.
Esther
E
Schnettler
b Department of Life Sciences , Imperial College London , London , UK.
Andrea
A
Crisanti
b Department of Life Sciences , Imperial College London , London , UK.
Clelia
C
Supparo
b Department of Life Sciences , Imperial College London , London , UK.
George K
GK
Christophides
c The European Molecular Biology Laboratory , The European Bioinformatics Institute, Wellcome Trust Genome Campus , Cambridge , UK.
Paul J
PJ
Kersey
c The European Molecular Biology Laboratory , The European Bioinformatics Institute, Wellcome Trust Genome Campus , Cambridge , UK.
Gareth L
GL
Maslen
d Laboratory of Entomology , Wageningen University and Research Centre , Wageningen , The Netherlands.
Willem
W
Takken
d Laboratory of Entomology , Wageningen University and Research Centre , Wageningen , The Netherlands.
Constantianus J M
CJ
Koenraadt
e Polo d'Innovazione di Genomica, Genetica e Biologia , Perugia , Italy.
Clelia F
CF
Oliva
f Centre de Recerca en Sanitat Animal (CReSA) , Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Campus UAB , Barcelona , Spain.
Núria
N
Busquets
f Centre de Recerca en Sanitat Animal (CReSA) , Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Campus UAB , Barcelona , Spain.
F Xavier
FX
Abad
g Arboviruses and Insect Vectors Unit, Department of Virology , Institut Pasteur , Paris cedex 15 , France.
Anna-Bella
AB
Failloux
h Department of Vector Biology , Max-Planck-Institut für Infektionsbiologie, Campus Charité Mitte , Berlin , Germany.
Elena A
EA
Levashina
i Integrative Entomology Group, Vector-borne Viral Diseases Programme , The Pirbright Institute , Surrey , UK.
Anthony J
AJ
Wilson
j Swiss National Centre for Vector Entomology, Institute of Parasitology , University of Zürich , Zürich , Switzerland.
Eva
E
Veronesi
k Department of Parasites and Insect Vectors , Institut Pasteur, Unit of Insect Vector Genetics and Genomics , Paris cedex 15 , France.
Maëlle
M
Pichard
k Department of Parasites and Insect Vectors , Institut Pasteur, Unit of Insect Vector Genetics and Genomics , Paris cedex 15 , France.
Sarah
S
Arnaud Marsh
l MIVEGEC "Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle" , UMR IRD224-CNRS5290-Université de Montpellier , Montpellier France.
Frédéric
F
Simard
k Department of Parasites and Insect Vectors , Institut Pasteur, Unit of Insect Vector Genetics and Genomics , Paris cedex 15 , France.|m CNRS Unit of Hosts, Vectors and Pathogens (URA3012) , Institut Pasteur , Paris cedex 15 , France.
Kenneth D
KD
Vernick
D000818:Animals; D001102:Arbovirus Infections / Q000517:prevention & control* / Q000635:transmission; D001103:Arboviruses / Q000502:physiology; D001179:Arthropod Vectors / Q000502:physiology*; D009033:Culicidae / Q000502:physiology*; D005060:Europe; D054884:Host-Pathogen Interactions; D006801:Humans; D008288:Malaria / Q000517:prevention & control* / Q000635:transmission; D010572:Pest Control, Biological; D010961:Plasmodium / Q000502:physiology; D012106:Research; D011795:Surveys and Questionnaires; D013987:Ticks / Q000502:physiology*; D020577:Wolbachia / Q000502:physiology
Community survey; Research infrastructures; Research requirements; Vector biology; Vector-borne diseases; Vector–pathogen interactions
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