Shear accumulation as a means for evaluating risk of thromboembolic events in novel endovascular stent graft designs.
This study proposes to establish a simulation-based technique for evaluating shear accumulation in stent grafts and to use the technique to assess the performance of a novel branched stent graft system.



Computational fluid dynamics models, with transient boundary conditions, particle injection, and rigid walls, simplifying assumptions were developed and used to evaluate the shear accumulation in various stent graft configurations with a healthy aorta as comparison.



Shear streamlines are presented for the various configurations. Shear accumulation was also calculated for each configuration. The number of particles with shear accumulations >3.5 Pa-s for each configuration was compared with the shear accumulation values of commercially available mechanical aortic valves from the literature.



The stent graft configuration with the diaphragm does have particles with shear accumulation >3.5 Pa-s. However, the percentage of particles with shear accumulation above 3.5 Pa-s is less than the two commercially available mechanical aortic valves, and more surprisingly, is smaller than in the healthy aorta.
Department of Mechanical Engineering, South Dakota State University, Brookings, SDak.
Taylor
T
Suess
Sanford USD School of Medicine, Sanford Health, Sioux Falls, SDak.
Joseph
J
Anderson
Sanford USD School of Medicine, Sanford Health, Sioux Falls, SDak.
Andrea
A
Sherman
Sanford Vascular Surgery, Sanford Health, Sioux Falls, SDak.
Tyler
T
Remund
Sanford Vascular Surgery, Sanford Health, Sioux Falls, SDak.
Kathryn
K
Pohlson
Department of Biomedical Engineering, University of South Dakota, Sioux Falls, SDak.
Gopinath
G
Mani
Department of Mechanical Engineering, South Dakota State University, Brookings, SDak.
Stephen
S
Gent
Sanford Vascular Surgery, Sanford Health, Sioux Falls, SDak. Electronic address: patrick.kelly@sanfordhealth.org.
Patrick
P
Kelly
D001013:Aorta, Thoracic / Q000503:physiopathology / Q000601:surgery*; D001783:Blood Flow Velocity; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation*; D003198:Computer Simulation; D057510:Endovascular Procedures / Q000009:adverse effects* / Q000295:instrumentation*; D006801:Humans; D057446:Hydrodynamics; D008955:Models, Cardiovascular; D011474:Prosthesis Design; D011673:Pulsatile Flow; D012039:Regional Blood Flow; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents; D013314:Stress, Mechanical; D013923:Thromboembolism / Q000209:etiology* / Q000503:physiopathology