Data from computational analysis of the peptide linkers in the MocR bacterial transcriptional regulators.
Detailed data from statistical analyses of the structural properties of the inter-domain linker peptides of the bacterial regulators of the family MocR are herein reported. MocR regulators are a recently discovered subfamily of bacterial regulators possessing an N-terminal domain, 60 residue long on average, folded as the winged-helix-turn-helix architecture responsible for DNA recognition and binding, and a large C-terminal domain (350 residue on average) that belongs to the fold type-I pyridoxal 5'-phosphate (PLP) dependent enzymes such aspartate aminotransferase. Data show the distribution of several structural characteristics of the linkers taken from bacterial species from five different phyla, namely Actinobacteria, Alpha-, Beta-, Gammaproteobacteria and Firmicutes. Interpretation and discussion of reported data refer to the article "Structural properties of the linkers connecting the N- and C- terminal domains in the MocR bacterial transcriptional regulators" (T. Milano, S. Angelaccio, A. Tramonti, M. L. Di Salvo, R. Contestabile, S. Pascarella, 2016) [1].
Dipartimento di Scienze biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, 00185 Roma, Italy.
Sebastiana
S
Angelaccio
Dipartimento di Scienze biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, 00185 Roma, Italy.
Teresa
T
Milano
Istituto di Biologia e Patologia Molecolari, Consiglio Nazionale delle Ricerche, 00185 Roma, Italy.
Angela
A
Tramonti
Dipartimento di Scienze biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, 00185 Roma, Italy.
Martino Luigi
ML
Di Salvo
Dipartimento di Scienze biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, 00185 Roma, Italy.
Roberto
R
Contestabile
Dipartimento di Scienze biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, 00185 Roma, Italy.
Stefano
S
Pascarella
Dyad propensity; Flexibility; GabR; Hydrophobicity; Linker engineering; Linker length; Linker peptide; MocR regulators; PdxR; Residue propensity
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