Evaluating Recall and Recognition Memory Using the Montreal Cognitive Assessment: Applicability for Alzheimer's and Huntington's Diseases.
We sought to investigate whether the Montreal Cognitive Assessment (MoCA) could provide a brief assessment of recall and recognition using Huntington disease (HD) and Alzheimer disease (AD) as disorders characterized by different memory deficits. This study included 80 participants with HD, 64 participants with AD, and 183 community-dwelling control participants. Random-effects hierarchical logistic regressions were performed to assess the relative performance of the normal control (NC), participants with HD, and participants with AD on verbal free recall, cued recall, and multiple-choice recognition on the MoCA. The NC participants performed significantly better than participants with AD at all the 3 levels of assessment. No difference existed between participants with HD and NC for cued recall, but NC participants performed significantly better than participants with HD on free recall and recognition. The participants with HD performed significantly better than participants with AD at all the 3 levels of assessment. The MoCA appears to be a valuable, brief cognitive assessment capable of identifying specific memory deficits consistent with known differences in memory profiles.
Department of Neurosciences, University of California, San Diego, CA, USA cavanliew@yahoo.com.|Department of Psychology, San Diego State University, San Diego, CA, USA.
Charles
C
Van Liew
Joint Doctoral Program in Clinical Psychology, University of California, San Diego/San Diego State University, San Diego, CA, USA.
Maya S
MS
Santoro
Department of Neurosciences, University of California, San Diego, CA, USA.
Jody
J
Goldstein
Department of Neurosciences, University of California, San Diego, CA, USA.
Shea
S
Gluhm
Joint Doctoral Program in Clinical Psychology, University of California, San Diego/San Diego State University, San Diego, CA, USA.
Paul E
PE
Gilbert
Department of Neurosciences, University of California, San Diego, CA, USA.
Jody
J
Corey-Bloom
D000368:Aged; D000544:Alzheimer Disease / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000150:complications / Q000503:physiopathology*; D008297:Male; D008569:Memory Disorders / Q000209:etiology / Q000503:physiopathology*; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D021641:Recognition, Psychology / Q000502:physiology*
Alzheimer disease; Huntington disease; Montreal Cognitive Assessment (MoCA); recall; recognition
J Psychiatr Res. 1975 Nov;12(3):189-98
1202204
Mov Disord. 2010 Feb 15;25(3):401-4
20108371
Mov Disord. 2008 Jan 30;23(2):297-9
18044697
Arch Neurol. 1993 Apr;50(4):374-9
8460958
J Huntingtons Dis. 2013;2(3):305-13
25062678
Mov Disord. 1996 Mar;11(2):136-42
8684382
Appl Neuropsychol Adult. 2013;20(1):33-40
23373682
Dement Geriatr Cogn Disord. 2014;37(1-2):95-103
24107412
J Int Neuropsychol Soc. 2001 Jan;7(1):33-44
11253840
Mov Disord. 2013 Oct;28(12):1744-7
23798501
Mov Disord. 2008 May 15;23(7):1043-1046
18381646
Neurobiol Dis. 2012 Jun;46(3):590-6
22484304
Front Biosci (Schol Ed). 2013 Jan 01;5(1):1-18
23277034
Brain Cogn. 1988 Jun;7(3):335-47
2969744
Mov Disord. 2010 Oct 15;25(13):2229-33
20721924
Am J Alzheimers Dis Other Demen. 2015 Mar;30(2):145-52
24990889
Prog Neurobiol. 2008 Nov;86(3):141-55
18824075
Alzheimers Dement. 2013 Sep;9(5):529-37
23260866
Int Psychogeriatr. 2016 May;28(5):825-32
26620850
J Neurol. 2004 Aug;251(8):935-42
15316797
Int J Geriatr Psychiatry. 2016 Mar;31(3):264-72
26177715
Alzheimers Dement. 2013 May;9(3):284-94
22841497
Brain Cogn. 1990 Jul;13(2):282-95
2143907
Psychon Bull Rev. 2002 Sep;9(3):426-37
12412885
J Clin Exp Neuropsychol. 1990 Oct;12(5):729-44
2147923
J Am Geriatr Soc. 2005 Apr;53(4):695-9
15817019
Int J Geriatr Psychiatry. 2009 Feb;24(2):197-201
18850670
Cold Spring Harb Perspect Med. 2012 Apr;2(4):a006171
22474609
Int J Geriatr Psychiatry. 2010 Feb;25(2):111-20
19582756