[Urinary incontinence and sexual dysfunction after treatment of localized prostate cancer: Results from a population aged less than 65years old].
BACKGROUND
An increasing number of patients with prostate cancer (PC) are diagnosed and treated. The aim of this study was to investigate urinary incontinence (UI) and sexual dysfunction (SD) two years after treatment for localized prostate cancer (PC).


METHODS
This study followed all cases of localized PC diagnosed between 2008 and 2009 in men aged≤65years old and still alive two years after treatment. In total, 437 men were recruited. Data were collected using a standardized questionnaire and by cross-checking with data from the cancer registry. Descriptive and comparative analyses were performed to evaluate persisting UI and SD at 2years.


RESULTS
At two years after treatment, UI was persistent in 48.8%; 41.2% had used urinary protections, and 39.2% had used at least 1 pad/day; 55.2% reported financial difficulties for purchasing protective pads. In total, 22.7% did not consult a specialist for UI. SD was persistent in 82.8%; 30.4% did not consult a specialist for SD. SD had a negative impact on the sex life of patients and their partners. After adjustment for cancer stage, prostatectomy was significantly associated with persisting UI and SD at two years.


CONCLUSIONS
Two years after treatment, rates of persisting UI and/or SD remain high. Treatment by prostatectomy was significantly associated with an increased risk of persisting adverse effects at two years. The different toxicities between treatments should be presented to patients before initiating therapy in order to encourage the patient to contributed to shared treatment decision-making.
Registre des tumeurs de l'Hérault, 208, avenue des apothicaires, 34298 Montpellier, France. Electronic address: faiza.bessaoud@orange.fr.
Faïza
F
Bessaoud
Institut universitaire de recherche clinique (IURC), 641, avenue du Doyen-Gaston-Giraud, 34093 Montpellier cedex, France.
Mattéa
M
Orsini
Centre hospitalo-universitaire, hôpital Lapeyronie, service d'urologie, 345, rue du Muscadet, 34090 Montpellier, France.
François
F
Iborra
Clinique Beau-Soleil, service d'urologie, 119, rue de Lodève, 34070 Montpellier, France.
Xavier
X
Rebillard
Clinique Beau-Soleil, service d'urologie, 119, rue de Lodève, 34070 Montpellier, France.
Antoine
A
Faix
Centre régional de lutte contre le cancer (CRLCC), 208, avenue des Apothicaires, 34298 Montpellier, France.
Maryvonne
M
Soulier
Institut universitaire de recherche clinique (IURC), 641, avenue du Doyen-Gaston-Giraud, 34093 Montpellier cedex, France.
Jean-Pierre
JP
Daurès
Registre des tumeurs de l'Hérault, 208, avenue des apothicaires, 34298 Montpellier, France.
Brigitte
B
Trétarre
D000367:Age Factors; D007172:Erectile Dysfunction / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D011468:Prostatectomy / Q000009:adverse effects*; D011471:Prostatic Neoplasms / Q000628:therapy*; D012747:Sexual Partners; D011795:Surveys and Questionnaires; D013997:Time Factors; D014549:Urinary Incontinence / Q000453:epidemiology* / Q000209:etiology
Cancer de la prostate; Dysfonctionnement sexuel; Incontinence urinaire; Prostate cancer; Sexual dysfunction; Traitements; Treatment; Urinary incontinence