Metastatic Malignant Pilomatrixoma in an 8-Year-Old Girl Misdiagnosed as a Recurrent Pilomatrixoma.
Malignant pilomatrixoma or pilomatrix carcinoma is a rare, locally aggressive malignant neoplasm, derived from the hair follicle with a high propensity for local recurrence. Only a few cases of metastatic pilomatrixoma have been described in the literature. Till date, only 17 cases have been reported in the English-language medical literature, most commonly occurring associated with local recurrence in adults. We report the first case in children of a metastatic malignant pilomatrixoma in an 8-year-old girl presenting with a recurrent pilomatrix carcinoma of the forehead with metastases in cervical and parotid lymph nodes.
*Fundación Universitaria de Ciencias de la Salud, Bogotá, Colombia; and Departments of † Dermatology, and ‡Pathology, Hospital de San José, Bogotá, Colombia.
Mario N
MN
Otero
Carolina P
CP
Trujillo
Rafael
R
Parra-Medina
Samuel D
SD
Morales
D014408:Biomarkers, Tumor / Q000032:analysis; D002648:Child; D003951:Diagnostic Errors; D005260:Female; D006201:Hair Diseases / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis / Q000175:diagnosis* / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D018296:Pilomatrixoma / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology
D014408:Biomarkers, Tumor