Neural Mechanisms of Dorsal and Ventral Visual Regions during Text Reading.
When reading a narrative text, both the dorsal and ventral visual systems are activated. To illustrate the patterns of interactions between the dorsal and ventral visual systems in text reading, we conducted analyses of functional connectivity (FC) and effective connectivity (EC) in a left-hemispheric network for reading-driven functional magnetic resonance imaging (fMRI) and resting-state fMRI (rs-fMRI) data. In reading-driven fMRI (Experiment 1), we found significant FCs among the left middle frontal gyrus (MFG), the left intraparietal sulcus (IPS), and the visual word form area (VWFA), and there were top-down effects from the left MFG to the left IPS, from the left MFG to the VWFA, and from the left IPS to the VWFA. In rs-fMRI (Experiment 2), we identified FCs and ECs for MFG-IPS and IPS-VWFA connections. In addition, the brain-behavior relationship in resting states showed that the dorsal connection was more associated with reading fluency relative to lexical decision. The combination of two experiments revealed that the MFG-IPS and the VWFA-IPS connections were shared connections both in reading-driven fMRI and rs-fMRI, and that the MFG-VWFA was specific connectivity in reading-driven fMRI. These results suggest that top-down effects from the dorsal visual system to ventral visual system play an important role in text reading.
Beijing Key Lab of Learning and Cognition, Department of Psychology, Capital Normal UniversityBeijing, China; Beijing Advanced Innovation Center for Imaging Technology, Capital Normal UniversityBeijing, China; State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal UniversityBeijing, China.
Wei
W
Zhou
School of Psychology, Shaanxi Normal University Xi'an, China.
Xiaojuan
X
Wang
State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University Beijing, China.
Zhichao
Z
Xia
State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University Beijing, China.
Yanchao
Y
Bi
Department of Psychology and Center for Brain, Behavior and Cognition, Pennsylvania State University, University Park PA, USA.
Ping
P
Li
State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University Beijing, China.
Hua
H
Shu
dorsal visual region; effective connectivity; functional connectivity; text reading; ventral visual region
J Neurosci. 2013 Oct 2;33(40):15978-88
24089502
Brain Cogn. 2008 Dec;68(3):255-70
18835656
Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13507-12
17679691
J Neurosci. 2011 Jun 1;31(22):8239-47
21632945
Brain. 2000 Feb;123 ( Pt 2):291-307
10648437
Trends Cogn Sci. 2011 Jun;15(6):254-62
21592844
J Cogn Neurosci. 2013 Nov;25(11):1944-56
23691986
Nat Rev Neurosci. 2002 Mar;3(3):201-15
11994752
Neuroimage. 2006 Jun;31(2):513-9
16497520
Psychol Res. 2008 Nov;72(6):675-88
18936964
Neuroimage. 2010 May 1;50(4):1690-701
20079856
Biol Cybern. 2000 Jul;83(1):35-45
10933236
Neuroimage. 2003 Oct;20(2):693-712
14568445
PLoS One. 2015 May 27;10(5):e0124388
26017384
Cereb Cortex. 2010 Nov;20(11):2549-59
20139150
Exp Brain Res. 2009 Jan;192(3):489-97
19030851
Brain Connect. 2011;1(1):13-36
22432952
Annu Rev Psychol. 2005;56:57-87
15709929
Neuroimage. 2004 May;22(1):11-21
15109993
Science. 2007 Mar 30;315(5820):1860-2
17395832
Front Hum Neurosci. 2015 Sep 10;9:495
26441595
Neuropsychologia. 1971 Mar;9(1):97-113
5146491
Psychol Neurosci. 2009;2(2):111-123
21526132
J Cogn Neurosci. 2002 Nov 15;14(8):1184-99
12495525
Hum Brain Mapp. 2002 Apr;15(4):247-62
11835612
Neuroimage. 2008 Jul 15;41(4):1408-25
18499478
Cereb Cortex. 2012 Mar;22(3):537-49
21690259
Hum Brain Mapp. 2015 Jan;36(1):304-12
25196948
Annu Rev Neurosci. 2000;23:315-41
10845067
J Neurosci. 2008 Oct 1;28(40):10056-61
18829963
Neuropsychologia. 2013 Jul;51(8):1571-83
23707507
J Neurosci. 2015 Feb 25;35(8):3293-7
25716830
Brain. 2002 May;125(Pt 5):1054-69
11960895
PLoS One. 2011;6(9):e25031
21949842
Front Syst Neurosci. 2012 Mar 06;6:7
22408609
Cereb Cortex. 2013 Jan;23(1):223-9
22298730
Psychol Rev. 2001 Jan;108(1):204-56
11212628
Neuroimage. 2011 Sep 15;58(2):323-9
20202481
Sci Rep. 2015 Aug 03;5:12686
26235228
Brain Connect. 2012;2(1):25-32
22432927
Hum Brain Mapp. 2014 Apr;35(4):1668-80
23670980
Q J Exp Psychol (Hove). 2009 Aug;62(8):1457-506
19449261
PLoS One. 2014 Jun 10;9(6):e98860
24914775
J Neurolinguistics. 2015 Feb;33:172-186
26294811
PLoS One. 2013 Jul 04;8(7):e68910
23861951
J Neurosci. 2010 Nov 17;30(46):15535-45
21084608
Cereb Cortex. 2015 Oct;25(10):3502-14
25169986
J Psycholinguist Res. 2013 Oct;42(5):433-50
22923217
Front Hum Neurosci. 2014 Dec 23;8:1024
25566039
Front Hum Neurosci. 2013 Jul 29;7:384
23908615
Trends Neurosci. 1992 Jan;15(1):20-5
1374953
Front Syst Neurosci. 2010 May 14;4:13
20577591
J Neurosci. 2003 May 15;23 (10 ):3990-8
12764083
Neuroimage. 2014 Nov 15;102 Pt 2:848-60
25173413
Neuron. 2013 Aug 21;79(4):814-28
23972602
Front Comput Neurosci. 2011 Feb 08;5:5
21369354
Curr Opin Neurobiol. 1994 Apr;4(2):157-65
8038571
Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11073-8
17576922
Brain Res. 2008 Jan 16;1189:78-89
18068690
Cereb Cortex. 2015 Sep;25(9):2416-26
24642423
Trends Cogn Sci. 2010 Feb;14(2):57-63
20080053
Neuroimage. 2005 Mar;25(1):230-42
15734358
Neuroimage. 2004 May;22(1):466-76
15110040
Neuroimage. 2012 Aug 15;62(2):816-47
22584224
Cereb Cortex. 2014 Jun;24(6):1601-8
23382515
Neuroimage. 2000 Jun;11(6 Pt 1):805-21
10860804