A Prospective Study of Herpes Zoster in Children.
BACKGROUND
Herpes zoster (HZ) is a dermatomal viral infection, caused by reactivation of varicella zoster virus (VZV) that persists in the posterior root ganglion. HZ is uncommonly reported in immunocompetent children. It may be due to intrauterine VZV infection or secondary to postnatal exposure to VZV at an early age.


OBJECTIVE
Our study was to review clinico-epidemiological data for HZ in children for early diagnosis and treatment to prevent complications.


METHODS
A prospective observational study was conducted from January 2013 to December 2014. Consecutive cases clinically diagnosed as HZ in the pediatric age group were taken up.


RESULTS
We report the clinico-epidemiological study of 26 cases of HZ, their benign course and recovery among children.


CONCLUSIONS
HZ is a rare disease in childhood. Varicella in early childhood is a risk factor of HZ in immunocompromised and immunocompetent children. Childhood zoster occurs in either healthy or underlying immunodeficient children. The appearance of HZ in a young child does not always imply an underlying immunodeficiency or malignancy. But the identification of HZ with or without immunodeficiency is of prime importance from the treatment and prognostic point of view and should be considered in the differential diagnosis of vesicular eruptions. The prognosis is generally good in healthy children.
Department of Dermatology, Venereology and Leprosy, Gandhi Medical College, Hyderabad, Telangana, India.
Bhumesh Kumar
BK
Katakam
Department of Dermatology, Venereology and Leprosy, Gandhi Medical College, Hyderabad, Telangana, India.
Geeta
G
Kiran
Department of Dermatology, Venereology and Leprosy, Gandhi Medical College, Hyderabad, Telangana, India.
Udaya
U
Kumar
Children; herpes zoster; varicella zoster virus
N Engl J Med. 1982 Aug 12;307(7):393-7
6979711
Cochrane Database Syst Rev. 2014 Feb 06;(2):CD006866
24500927
Arch Dermatol. 2004 Oct;140(10):1268-72
15492192
Dermatol Online J. 2005 Dec 01;11(3):26
16409922
Herpes. 2007 Sep;14 Suppl 2:40-4
17939895
Lancet. 1994 Jun 18;343 (8912):1548-51
7802767
Can Fam Physician. 2011 Oct;57(10):1127-31
21998225
Clin Infect Dis. 2007 Jan 1;44 Suppl 1:S1-26
17143845
Postgrad Med. 2013 Sep;125(5):78-91
24113666
MMWR Recomm Rep. 2008 Jun 6;57(RR-5):1-30; quiz CE2-4
18528318
N Engl J Med. 1986 Jun 12;314(24):1542-6
3012334
Arch Intern Med. 1995 Aug 7-21;155(15):1605-9
7618983
Br J Cancer. 2004 Oct 4;91(7):1275-9
15328522
J Infect Dis. 2011 Feb 1;203(3):316-23
21177308
J Am Acad Dermatol. 1998 Aug;39(2 Pt 1):207-10
9704830
J Am Acad Dermatol. 2007 Dec;57(6 Suppl):S136-42
18021865
J Am Acad Dermatol. 1988 Jan;18(1 Pt 2):218-21
2448353
BMJ. 2003 Apr 5;326(7392):748-50
12676845