[Impact of PM2.5on daily outpatient numbers for respiratory diseases in Shenzhen, China].
Objective:To assess the association between the concentration of the air pollutant PM2.5and daily outpatient visits for respiratory disease.Methods:All records of daily outpatient visits to three hospitals in Shenzhen from January 1 to December 31, 2013 were collected. Daily air pollution monitoring and meteorology data from the same period were also collected in Shenzhen. The data were analyzed using a semiparametric generalized additive model with Poisson distribution of time series analysis controlling for long-term and seasonal trends, flu, DOW, public holidays, and meteorological factors. The excess risk(ER)of respiratory disease and its 95%CIvalue were calculated, along with the incremental increase of 10 μg/m3in PM2.5concentration.Results:Number of outpatient visits for respiratory diseases totaled 1 428 672(daily range: 1 790-5 228). The annual average PM2.5concentration was 40.2 μg/m3(daily range: 7.2-137.1 μg/m3). The lag1 factor had the most significant impact on the lag effect. We estimated that a 10 μ g/m3increase in day-before PM2.5concentration was associated with a 1.809%(95%CI: 1.709%-1.909%)ERof visits for respiratory disease. After controlling for other pollutants(NO2, CO, and O3), the effect remained stable. When NO2, CO, and O3were introduced separately, for every 10 μg/m3rise in PM2.5concentration, the excess risk of daily outpatient visits for respiratory disease was 1.814%(95%CI: 1.706%-1.923%), 2.780%(95%CI: 2.668%-2.892%), and 1.513%(95%CI: 1.403%-1.624%), respectively. With simultaneous control of NO2and O3, NO2and CO, and CO and O3, for every 10 μg/m3rise in PM2.5concentration, the excess risk of respiratory disease was 1.369%(95%CI: 1.242%-1.497%), 2.709%(95%CI: 2.590%-2.828%), and 2.577%(95%CI: 2.452%-2.702%), respectively. With simultaneous control of NO2, CO, and O3, for every 10 μg/m3rise in PM2.5concentration, the excess risk of respiratory disease was 2.370%(95%CI: 2.231%-2.509%).Conclusions:PM2.5can increase the risk of outpatient visits for respiratory disease in Shenzhen.
Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
C Q
CQ
Peng
J F
JF
Cai
S Y
SY
Yu
Z J
ZJ
Cao
Y X
YX
Liao
N
N
Liu
L
L
He
L
L
Zhang
J
J
Zheng
X M
XM
Shi
J Q
JQ
Cheng
D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D000397:Air Pollution / Q000009:adverse effects* / Q000032:analysis; D002681:China / Q000453:epidemiology; D004781:Environmental Exposure; D006801:Humans; D008685:Meteorological Concepts; D008962:Models, Theoretical; D010045:Outpatients / Q000706:statistics & numerical data*; D052638:Particulate Matter / Q000009:adverse effects* / Q000032:analysis; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000453:epidemiology; D012621:Seasons
D000393:Air Pollutants; D052638:Particulate Matter