A Case for Distributed Control of Local Stem Cell Behavior in Plants.
The root meristem has a centrally located group of mitotically quiescent cells, to which current models assign a stem cell organizer function. However, evidence is emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges from the lack of cell displacement at the border of opposing differentiation gradients. We term this a "stagnation" model due to its reliance on passive mechanics. The position of stem cells is established by two opposing axes that reciprocally control each other's differentiation. Such broad tissue organization programs would allow plants, like some animal systems, to rapidly reconstitute stem cells from non-stem-cell tissues.
Department of Biology, Center for Genomics and Systems Biology, New York University, New York, NY 10003, USA.
Ramin
R
Rahni
The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University, Rehovot 76100, Israel.
Idan
I
Efroni
Department of Biology, Center for Genomics and Systems Biology, New York University, New York, NY 10003, USA. Electronic address: ken.birnbaum@nyu.edu.
Kenneth D
KD
Birnbaum
D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development; D029681:Arabidopsis Proteins / Q000096:biosynthesis / Q000235:genetics; D002454:Cell Differentiation / Q000235:genetics*; D018506:Gene Expression Regulation, Plant; D006706:Homeostasis / Q000235:genetics; D018519:Meristem / Q000235:genetics* / Q000254:growth & development; D018517:Plant Roots / Q000166:cytology / Q000235:genetics; D015398:Signal Transduction / Q000235:genetics; D013234:Stem Cells / Q000166:cytology*
D029681:Arabidopsis Proteins
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