Peripartum Cardiomyopathy in a Pakistani Cohort.
OBJECTIVE
To describe the demographics, risk factors, and clinical presentation in Pakistani patients with peripartum cardiomyopathy.


METHODS
A descriptive observational study.


METHODS
Rawalpindi Institute of Cardiology, Rawalpindi, from June 2014 to June 2015.


METHODS
Seventy patients meeting criteria of peripartum cardiomyopathy were included in the study. Adetailed history, physical examination and investigations were done. Epidemiologic data, risk factors, New York Heart Association (NYHA) class and echocardiographic findings were recorded. Statistical analyses were done using SPSS version 19.


RESULTS
The mean age was 28.66 ±4.57 years. Mean parity and weight was 3.04 ±1.7 and 60.97 ±12.40 Kg, respectively. Fifty-five (78.6%) cases were diagnosed in the postpartum period. Thirty-three (50.8%) and 31 patients (44.7%) presented in NYHA- III and IV classes, respectively. Pregnancy-induced hypertension was seen in 16 (22.9%) cases, diabetes in 6 (8.6%), and twin pregnancy in 2 (2.9%) cases. The mean hemoglobin and brain natriuretic peptide (BNP) was 11.26 ±1.61 gm/dl and 1583.70 ±1237.65 pg/ml, respectively. Echocardiography showed mean ejection fraction of 21.74 ±7.45%. Left ventricle systolic and diastolic diameters were 53.71 ±9.74 mm and 63.37 ±8.48 mm, respectively.


CONCLUSIONS
Peripartum cardiomyopathy was seen in younger women with higher parity and pregnancy induced hypertension, often manifesting in the postpartum period with NHYAclass III and IV status.
Department of Obstetric and Gynecology,Rawalpindi Institute of Cardiology, Rawal Road, Rawalpindi.
Rubab
R
Munir
Department of Cardiology,Rawalpindi Institute of Cardiology, Rawal Road, Rawalpindi.
Sajjad
S
Hussain
Department of Cardiology,Rawalpindi Institute of Cardiology, Rawal Road, Rawalpindi.
Azhar Mahmood
AM
Kayani
D000293:Adolescent; D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis* / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology; D004452:Echocardiography; D005260:Female; D006785:Hospitals, University; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology; D008423:Maternal Age; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010154:Pakistan / Q000453:epidemiology; D010298:Parity; D049590:Postpartum Period; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D011256:Pregnancy Outcome; D012307:Risk Factors; D016896:Treatment Outcome; D055815:Young Adult
D020097:Natriuretic Peptide, Brain