Difference in dose-volumetric data between the analytical anisotropic algorithm, the dose-to-medium, and the dose-to-water reporting modes of the Acuros XB for lung stereotactic body radiation therapy.
The purpose of this study was to evaluate the difference in dose-volumetric data between the analytical anisotropic algorithms (AAA) and the two dose reporting modes of the Acuros XB, namely, the dose to water (AXB_Dw) and dose to medium (AXB_Dm) in lung stereotactic body radiotherapy (SBRT). Thirty-eight plans were generated using the AXB_Dm in Eclipse Treatment Planning System (TPS) and then recalculated with the AXB_Dw and AAA, using identical beam setup. A dose of 50 Gy in 4 fractions was prescribed to the isocenter and the planning target volume (PTV) D95%. The isocenter was always inside the PTV. The following dose-volumetric parameters were evaluated; D2%, D50%, D95%, and D98% for the internal target volume (ITV) and the PTV. Two-tailed paired Student's t-tests determined the statistical significance. Although for most of the parameters evaluated, the mean differences observed between the AAA, AXB_Dm, and AXB_Dw were statistically significant (p < 0.05), absolute differences were rather small, in general less than 5% points. The maximum mean difference was observed in the ITV D50% between the AXB_Dm and the AAA and was 1.7% points under the isocenter prescription and 3.3% points under the D95 prescription. AXB_Dm produced higher values than AXB_Dw with differences ranging from 0.4 to 1.1% points under isocenter prescription and 0.0 to 0.7% points under the PTV D95% prescription. The differences observed under the PTV D95% prescription were larger compared to those observed for the isocenter prescription between AXB_Dm and AAA, AXB_Dm and AXB_Dw, and AXB_Dw and AAA. Although statistically significant, the mean differences between the three algorithms are within 3.3% points.
Kyoto University. mampuya@kuhp.kyoto-u.ac.jp.
Wambaka A
WA
Mampuya
Mitsuhiro
M
Nakamura
Yoshinori
Y
Hirose
Kenji
K
Kitsuda
Takashi
T
Ishigaki
Takashi
T
Mizowaki
Masahiro
M
Hiraoka
D000465:Algorithms; D016880:Anisotropy; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D019047:Phantoms, Imaging; D016634:Radiosurgery; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods; D014867:Water / Q000737:chemistry*
D014867:Water
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