Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002-2012).
The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002-2012), which followed a Greek adult population (aged 18-89years). A total n=317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.
Department of Nutrition and Dietetics, School of Health Science & Education, Harokopio University, 70 Eleftheriou Venizelou Ave, Athens 17671, Greece.
Konstantinos D
KD
Tambalis
Department of Nutrition and Dietetics, School of Health Science & Education, Harokopio University, 70 Eleftheriou Venizelou Ave, Athens 17671, Greece. Electronic address: d.b.panagiotakos@usa.net.
Demosthenes B
DB
Panagiotakos
Department of Nutrition and Dietetics, School of Health Science & Education, Harokopio University, 70 Eleftheriou Venizelou Ave, Athens 17671, Greece; Faculty of Health, University of Canberra, Canberra, Australian Capital Territory, Australia.
Ekavi N
EN
Georgousopoulou
Faculty of Health, University of Canberra, Canberra, Australian Capital Territory, Australia.
Duane D
DD
Mellor
First Cardiology Clinic, School of Medicine, University of Athens, 114 Vasilissis Sofias Ave, Athens 11527, Greece.
Christina
C
Chrysohoou
Department of Nutrition and Dietetics, School of Health Science & Education, Harokopio University, 70 Eleftheriou Venizelou Ave, Athens 17671, Greece.
Georgia-Maria
GM
Kouli
First Cardiology Clinic, School of Medicine, University of Athens, 114 Vasilissis Sofias Ave, Athens 11527, Greece.
Dimitrios
D
Tousoulis
First Cardiology Clinic, School of Medicine, University of Athens, 114 Vasilissis Sofias Ave, Athens 11527, Greece.
Christodoulos
C
Stefanadis
First Cardiology Clinic, School of Medicine, University of Athens, 114 Vasilissis Sofias Ave, Athens 11527, Greece.
Christos
C
Pitsavos
D000367:Age Factors; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D006115:Greece / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008019:Life Style; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking
CVD; Physical activity level; Prospective study