Bilateral optic neuropathy, acral gangrene and visceral ischaemia as a rare presentation of calciphylaxis: A case report.
We report a case with calciphylaxis very rarely presenting with bilateral optic neuropathy, acral gangrene and visceral ischaemia. Bilateral papilloedaema was found in a 43 year-old female with chronic renal failure. Acral dry gangrene was observed. Pathological examination of her amputated thumb revealed calcification, thrombi, obstructive endovascular fibrotic areas in the walls of arteries. She was diagnosed with calciphylaxis. Bilateral optic neuropathy was defined secondary to calciphylaxis. Abdominal computerized tomography revealed prominent calcifications in mesenteric, spleen and renal arteries. She died eight months after the diagnosis. Calciphylaxis should be considered in the differential diagnosis of the optic neuropathy.
Neurology Clinics, Ankara Ataturk Education and Research Hospital, Bilkent, Ankara, Turkey.
Hatice Ferhan
HF
Komurcu
Neurology Clinics, Ankara Ataturk Education and Research Hospital, Bilkent, Ankara, Turkey.
Emel
E
Basar
Rheumatology Clinics, Ankara Ataturk Education and Research Hospital, Bilkent, Ankara, Turkey.
Orhan
O
Kucuksahin
Neurology Clinics, Ankara Ataturk Education and Research Hospital, Bilkent, Ankara, Turkey.
Ebru
E
Uz
Pathology Clinics, Ankara Ataturk Education and Research Hospital, Bilkent, Ankara, Turkey.
Huban Sibel
HS
Orhun Yavuz
Neurology Clinics, Ankara Ataturk Education and Research Hospital, Bilkent, Ankara, Turkey.
Omer
O
Anlar
D000328:Adult; D002115:Calciphylaxis / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005734:Gangrene / Q000209:etiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology; D009901:Optic Nerve Diseases / Q000209:etiology; D014057:Tomography, X-Ray Computed
Acral gangrene, Calciphylaxis, Case report, Optic neuropathy, Renal failure, Visceral ischemia.

