Compression properties and dissolution of bioactive glass S53P4 and n-butyl-2 cyanoacrylate tissue adhesive-composite.
Bioactive glass (BG)-containing fiber-reinforced composite implants, typically screw-retained, have started to be used clinically. In this study, we tested the mechanical strength of composites formed by a potential implant adhesive of n-butyl-2-cyanoacrylate glue and BG S53P4 particles. Water immersion for 3, 10 or 30 days had no adverse effect on the compression strength. When cyanoacrylate glue-BG-composites were subjected to simulated body fluid immersion, the average pH rose to 7.52 (SD 0.066) from the original value of 7.35 after 7 days, and this pH increment was smaller compared to BG particle-group or fibrin glue-BG-composite group. Based on these results n-butyl-2 cyanoacrylate glue, by potentially producing a strong adhesion, might be considered a possible alternative for fixation of BG S53P4 containing composite implants. However, the mechanical and solubility properties of the cyanoacrylate glue may not encourage the use of this tissue adhesive with BG particles.
Department of Otorhinolaryngology - Head and Neck Surgery, Turku University Hospital and University of Turku, Turku, Finland.
Jussi
J
Sarin
BioCity, Turku Biomaterials Research Program, Turku Clinical Biomaterials Centre - TCBC, Finland.
Markus
M
Hiltunen
Process Chemistry Centre, Laboratory of Inorganic Chemistry, Åbo Akademi University, Finland.
Leena
L
Hupa
Department of Otorhinolaryngology - Head and Neck Surgery, Turku University Hospital and University of Turku, Turku, Finland.
Jaakko
J
Pulkkinen
BioCity, Turku Biomaterials Research Program, Turku Clinical Biomaterials Centre - TCBC, Finland.|Department of Biomaterials Science and Turku Clinical Biomaterials Centre - TCBC, Institute of Dentistry, University of Turku, and City of Turku Welfare Division, Oral Health Care, Turku, Finland.
Pekka K
PK
Vallittu
Bioactive glass; S53P4; compression strength; cyanoacrylate adhesive; tissue glue; water sorption