Biosensing with Paper-Based Miniaturized Printed Electrodes-A Modern Trend.
From the bench-mark work on microfluidics from the Whitesides's group in 2007, paper technology has experienced significant growth, particularly regarding applications in biomedical research and clinical diagnostics. Besides the structural properties supporting microfluidics, other advantageous features of paper materials, including their versatility, disposability and low cost, show off the great potential for the development of advanced and eco-friendly analytical tools. Consequently, paper was quickly employed in the field of electrochemical sensors, being an ideal material for producing custom, tailored and miniaturized devices. Stencil-, inkjet-, or screen-printing are the preferential techniques for electrode manufacturing. Not surprisingly, we witnessed a rapid increase in the number of publications on paper based screen-printed sensors at the turn of the past decade. Among the sensing strategies, various biosensors, coupling electrochemical detectors with biomolecules, have been proposed. This work provides a critical review and a discussion on the future progress of paper technology in the context of miniaturized printed electrochemical biosensors.
UCIBIO, REQUIMTE, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Monte de Caparica, Portugal. c.silveira@fct.unl.pt.|Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa, Av. da República, 2780-157 Oeiras, Portugal. c.silveira@fct.unl.pt.
Célia M
CM
Silveira
UCIBIO, REQUIMTE, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Monte de Caparica, Portugal. tc.monteiro@campus.fct.unl.pt.
Tiago
T
Monteiro
UCIBIO, REQUIMTE, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Monte de Caparica, Portugal. mg.almeida@fct.unl.pt.|Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Instituto Superior de Ciências da Saúde Egas Moniz, Campus Universitário, Quinta da Granja, 2829-511 Caparica, Portugal. mg.almeida@fct.unl.pt.
Maria Gabriela
MG
Almeida
biosensors.; paper analytical device; printed electrodes; wax patterning
Nat Biotechnol. 2006 Aug;24(8):891-3
16900120
Angew Chem Int Ed Engl. 2007;46(8):1318-20
17211899
Anal Chem. 2009 Jul 15;81(14):5821-6
19485415
Anal Chem. 2008 Dec 1;80(23):9131-4
19551982
Colloids Surf B Biointerfaces. 2010 Apr 1;76(2):564-70
20097546
Lab Chip. 2010 Feb 21;10(4):477-83
20126688
Anal Chem. 2009 Aug 15;81(16):7091-5
20337388
Chem Soc Rev. 2010 May;39(5):1747-63
20419217
Analyst. 2010 May;135(5):845-67
20419231
Analyst. 2011 Jan 7;136(1):77-82
20871884
Biosens Bioelectron. 2012 Mar 15;33(1):309-12
22317834
PLoS Med. 2012;9(9):e1001306
22973183
Chem Soc Rev. 2013 Jan 21;42(2):450-7
23032871
Sensors (Basel). 2012;12(9):11505-26
23112667
Anal Chem. 2012 Nov 20;84(22):10071-6
23116304
Adv Biochem Eng Biotechnol. 2013;133:75-87
23192590
Anal Chim Acta. 2013 Jan 3;758:1-18
23245891
Bull World Health Organ. 2012 Dec 1;90(12):914-20
23284197
Chem Soc Rev. 2013 Apr 21;42(8):3184-96
23420144
Anal Bioanal Chem. 2013 Apr;405(11):3619-35
23430181
Anal Bioanal Chem. 2013 Apr;405(11):3423-6
23494271
Anal Bioanal Chem. 2013 Sep;405(24):7573-95
23604524
Lab Chip. 2013 Jun 21;13(12):2210-51
23652632
Anal Chim Acta. 2013 Jul 25;788:39-45
23845479
Biosens Bioelectron. 2014 Feb 15;52:13-9
24013212
Biosens Bioelectron. 2014 Feb 15;52:180-7
24055931
Biosens Bioelectron. 2014 Apr 15;54:585-97
24333570
Biosens Bioelectron. 2014 Jun 15;56:77-82
24469540
Nanotechnology. 2014 Mar 7;25(9):094006
24521980
Anal Chim Acta. 2014 Feb 27;813:90-6
24528665
Biosens Bioelectron. 2014 Nov 15;61:76-82
24858676
Analyst. 2014 Oct 7;139(19):4750-7
25089298
Clin Biochem Rev. 2014 Aug;35(3):155-67
25336761
Anal Chem. 2015 Jan 6;87(1):19-41
25375292
Talanta. 2015 Mar;134:194-199
25618657
Lab Chip. 2015 Jun 21;15(12):2538-58
25953427
Anal Chem. 2015 Sep 1;87(17):9009-15
26258588
Anal Chim Acta. 2015 Sep 3;891:136-43
26388372
Talanta. 2015 Dec 1;145:12-9
26459438
Biosens Bioelectron. 2016 May 15;79:193-7
26706941
Anal Bioanal Chem. 2016 Apr;408(11):2827-37
26780711
Sci Technol Adv Mater. 2013 Oct 18;14(5):054402
27877606
Pract Lab Med. 2015 Dec 09;4:22-29
28856189