Cytotoxic effects of bulk fill composite resins on human dental pulp stem cells.
Five bulk fill composite resins, including SDR, Tetric EvoCeram Bulk Fill (TEC), X-trafil (XTF), Sonic Fill (SF), Filtek Bulk Fill (FBF), were used in this study. Human dental pulp stem cells were cultured in 12-well culture dishes (3 × 104 cells per cm(2)) and stored in an incubator at 37°C and 5% CO2 for 1 day. On days 1, 7, 14, and 21 of co-culture, viable cells were measured using a WST-1 assay. Lower cell viability was observed with XTF and SDR bulk fill composite resins compared to the control group during the WST-1 assay. Although bulk fill composite resins provide advantages in practical applications, they are limited by their cytotoxic properties. (J Oral Sci 58, 299-305, 2016).
Department of Restorative Dentistry, Faculty of Dentistry, University of Inonu.
Reyhan
R
Şişman
Ayça
A
Aksoy
Muhammet
M
Yalçın
Erdal
E
Karaöz
D003782:Dental Pulp / Q000166:cytology / Q000187:drug effects*; D006801:Humans; D019279:Resin Cements / Q000009:adverse effects*; D013234:Stem Cells / Q000187:drug effects*
D019279:Resin Cements