Computation of Calcium Score With Dual-Energy Computed Tomography: A Phantom Study.
Dual-energy computed tomography (DECT) improves material and tissue characterization compared with single-energy CT; we sought to validate coronary calcium quantification in advancing cardiovascular DECT. In an anthropomorphic phantom, agreement between measurements was excellent, and Bland-Altman analysis demonstrated minimal bias. Compared with the known calcium mass for each phantom, calcium mass by DECT was highly accurate. Noncontrast DECT yields accurate calcium measures and warrants consideration in cardiac protocols for additional tissue characterizations.
From the Ohio State University Davis Heart and Lung Research Institute, Columbus, OH; †Department of Radiology, Weill Cornell Medical College, Dalio Institute of Cardiovascular Imaging, New York, NY; ‡Department of Epidemiology and Biostatistics, University of Maryland School of Public Health, College Park, MD; and §The Ohio State University Davis Heart and Lung Research Institute, Columbus, OH.
Vidhya
V
Kumar
James K
JK
Min
Xin
X
He
Subha V
SV
Raman
D017023:Coronary Angiography / Q000295:instrumentation / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D006801:Humans; D019047:Phantoms, Imaging; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015900:Radiography, Dual-Energy Scanned Projection / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*; D061205:Vascular Calcification / Q000000981:diagnostic imaging*
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