Dust Mite-Induced Perennial Allergic Rhinitis in Pediatric Patients and Sublingual Immunotherapy.
Allergic rhinitis (AR) is a common illness in children and can impair their quality of life. Furthermore, many children remain symptomatic despite maximizing systemic antihistamine and topical therapies. It is at this clinical juncture that immunotherapy may be considered. The efficacy and safety associated with both subcutaneous (SCIT) and sublingual (SLIT) approaches are reviewed and positioned as treatment options for pediatric patients, with specific focus on current literature as it relates to SLIT in children, including those with perennial allergic rhinitis. Although there is more extensive experience with SLIT treatment in Europe, grass and ragweed tablet forms of SLIT are approved in the US. Approaches to the care of pediatric patients with allergic rhinitis are presented.
Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.
Halie M
HM
Anderson
Johns Hopkins University School of Medicine, Baltimore, Md.
Robert A
RA
Wood
Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis. Electronic address: wwb@medicine.wisc.edu.
William W
WW
Busse
D000286:Administration, Sublingual; D000485:Allergens / Q000276:immunology / Q000627:therapeutic use*; D000818:Animals; D002648:Child; D003888:Desensitization, Immunologic / Q000379:methods*; D005062:European Union; D055317:Evidence-Based Practice; D006801:Humans; D007279:Injections, Subcutaneous; D006109:Poaceae / Q000276:immunology; D017410:Practice Guidelines as Topic; D039981:Pyroglyphidae / Q000276:immunology; D011788:Quality of Life; D065631:Rhinitis, Allergic / Q000276:immunology / Q000628:therapy*; D014481:United States
D000485:Allergens
Allergic rhinitis; Immunotherapy; Pediatric