Gliosarcoma: A rare variant of glioblastoma multiforme in paediatric patient: Case report and review of literature.
Gliosarcoma is rare central nervous system tumour and a variant of glioblastoma multiforme with bimorphic histological pattern of glial and sarcomatous differentiation. It occurs in elderly between 5(th) and 6(th) decades of life and extremely rare in children. It is highly aggressive tumour and managed like glioblastoma multiforme. A 12-year-old female child presented with complaints of headache and vomiting from 15 d and blurring of vision from 3 d. Magnetic resonance imaging of brain shows heterogeneous mass in right parieto-occipital cortex. A right parieto-occipito-temporal craniotomy with complete excision of mass revealed a primary glioblastoma on histopathological investigation. Treatment consists of maximum surgical excision followed by adjuvant radiotherapy. The etiopathogenesis, treatment modalities and prognosis is discussed. The available literature is also reviewed.
Ugan Singh Meena, Sumit Sharma, Sanjeev Chopra, Shashi Kant Jain, Department of Neurosurgery, Swai Man Singh Medical College, Rajasthan 302004, India.
Ugan Singh
US
Meena
Ugan Singh Meena, Sumit Sharma, Sanjeev Chopra, Shashi Kant Jain, Department of Neurosurgery, Swai Man Singh Medical College, Rajasthan 302004, India.
Sumit
S
Sharma
Ugan Singh Meena, Sumit Sharma, Sanjeev Chopra, Shashi Kant Jain, Department of Neurosurgery, Swai Man Singh Medical College, Rajasthan 302004, India.
Sanjeev
S
Chopra
Ugan Singh Meena, Sumit Sharma, Sanjeev Chopra, Shashi Kant Jain, Department of Neurosurgery, Swai Man Singh Medical College, Rajasthan 302004, India.
Shashi Kant
SK
Jain
Glioblastoma multiforme; Paediatric gliosarcoma; Radiotherapy; Surgery
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