Prenatal diagnosis and early postnatal management of pyriform sinus cyst: experience at a single medical center in mainland China.
OBJECTIVE
The aim of this study was to determine whether prenatal diagnosis of pyriform sinus cyst can improve the prognosis of this disorder.


METHODS
A retrospective review was performed in 15 neonates with a pyriform sinus cyst seen at a single center between 2010 and 2014. Among the 15 cases, the diagnosis was made prenatally in eight cases (PreD), while the diagnosis was made postnatally in seven cases (PostD). Neonatal outcome was compared in the two subgroups.


RESULTS
The mean gestational age at diagnosis of PreD was 27 ± 6.8 weeks, while the mean age at admission of PostD was 10.1 ± 8.8 days. Cervical mass, fever, respiratory distress, and hoarseness were common symptoms. The mean duration of postoperative mechanical ventilation was 11.5 ± 13.9 and 100.71 ± 80.0 h, respectively, in PreD and PostD (p < 0.01). The average postoperative length of stay and the length of hospital stay were 11.3 ± 3.34 and 19.6 ± 4.41 days in PreD, and 15.14 ± 8.28 and 24.14 ± 8.51 days in PostD, respectively.


CONCLUSIONS
Prenatal diagnosis and timely postnatal sequential intervention were associated with less complications and shortened duration of postoperative mechanical ventilation. © 2016 John Wiley & Sons, Ltd.
Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical University, Guangzhou, China.
Wei
W
Zhong
Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical University, Guangzhou, China.
Zhe
http://orcid.org/0000-0001-9116-9722
Z
Wang
Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical University, Guangzhou, China.
Qiu-Ming
QM
He
Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical University, Guangzhou, China.
Ting-Ting
TT
Shi
Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical University, Guangzhou, China.
Jia-Kang
JK
Yu
Prenatal Diagnosis & Fetal Medicine Center, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical University, Guangzhou, China.
Guang-Lan
GL
Zhang
Prenatal Diagnosis & Fetal Medicine Center, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical University, Guangzhou, China.
Dong-Zhi
DZ
Li
D002681:China; D003560:Cysts / Q000151:congenital / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male; D010608:Pharyngeal Diseases / Q000151:congenital / Q000000981:diagnostic imaging* / Q000601:surgery; D011379:Prognosis; D056144:Pyriform Sinus / Q000000981:diagnostic imaging*; D012121:Respiration, Artificial / Q000706:statistics & numerical data; D012189:Retrospective Studies