Marine copepod cytochrome P450 genes and their applications for molecular ecotoxicological studies in response to oil pollution.
Recently, accidental spills of heavy oil have caused adverse effects in marine organisms. Oil pollution can induce damages on development and reproduction, linking with detrimental effects on diverse molecular levels of genes and proteins in plankton and fish. However, most information was mainly focused on marine vertebrates and consequently, limited information was available in marine invertebrates. Furthermore, there is still a lack of knowledge bridging in vivo endpoints with the functional regulation of cytochrome P450 (CYP) genes in response to oil spill pollution in marine invertebrates. In this paper, adverse effects of oil spill pollution in marine invertebrates are summarized with the importance of CYP genes as a potential biomarker, applying for environmental monitoring to detect oil spill using marine copepods.
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea.
Jeonghoon
J
Han
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea; Marine Chemistry and Geochemistry Research Center, Korea Institute of Ocean Science and Technology, Ansan 15627, South Korea.
Eun-Ji
EJ
Won
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea.
Hye-Min
HM
Kang
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea.
Min-Chul
MC
Lee
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea; Department of Chemistry, College of Natural Sciences, Hanyang University, Seoul 04763, South Korea.
Chang-Bum
CB
Jeong
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea.
Hui-Su
HS
Kim
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea.
Dae-Sik
DS
Hwang
Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea. Electronic address: jslee2@skku.edu.
Jae-Seong
JS
Lee
D000818:Animals; D060829:Arthropod Proteins / Q000235:genetics* / Q000378:metabolism; D033342:Copepoda / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism; D054750:Ecotoxicology / Q000379:methods*; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods*; D059392:Petroleum Pollution / Q000009:adverse effects*
D060829:Arthropod Proteins; D003577:Cytochrome P-450 Enzyme System
Cytochrome P450 (CYP); Paracyclopina nana; Tigriopus japonicus; Water accommodated fraction (WAF); copepod