[Endometriosis : An often unrecognized pain disorder].
Endometriosis is a chronic disease of women during their reproductive age. The most typical symptoms are dysmenorrhoea, dyspareunia, dysuria, cyclical and acyclical pelvic pain, bleeding disorders and infertility. These symptoms lead to significant impairment of the quality of life and economic burden. The prevalence is estimated to be 2-20 % of all women in this age and due to this fact, it is one of the most frequently benign gynecological diseases. Not all women suffer from severe symptoms, but more than 50 % require ongoing treatment. Beside the severe physical impairment due to the pain, the high recurrence rate of 50-80 % also after surgical and/or hormonal treatment is problematic. The interval between onset of symptoms and diagnosis is approximately 6-8 years. These problems are a consequence of lack of knowledge about the pathogenesis of the disease and the pain mechanisms as well as the lack of awareness of physicians in this field.
Klinik für Gynäkologie, Endometriosezentrum Charité, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland. sylvia.mechsner@charite.de.
S
S
Mechsner
D000328:Adult; D017281:Cost of Illness; D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D004414:Dyspareunia / Q000209:etiology / Q000523:psychology / Q000628:therapy; D053159:Dysuria / Q000209:etiology / Q000523:psychology / Q000628:therapy; D004715:Endometriosis / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000523:psychology / Q000628:therapy; D008597:Menstrual Cycle / Q000502:physiology; D017699:Pelvic Pain / Q000209:etiology / Q000523:psychology / Q000628:therapy; D011788:Quality of Life / Q000523:psychology; D012008:Recurrence
Dysmenorrhea; Dyspareunia; Dysuria; Infertility; Pelvic pain
Fertil Steril. 2001 Mar;75(3):489-95
11239529
Fertil Steril. 1991 Apr;55(4):759-65
2010001
Gynecol Endocrinol. 2009 Mar;25(3):149-58
19347704
J Reprod Med. 1996 Apr;41(4):220-4
8728071
Hum Reprod. 2003 Apr;18(4):760-6
12660268
Hum Reprod. 2001 Mar;16(3):561-6
11228229
Mol Hum Reprod. 2002 Dec;8(12):1103-10
12468643
Am J Obstet Gynecol. 1981 Jun 15;140(4):401-4
6894667
Fertil Steril. 1986 Nov;46(5):801-6
3781000
Hum Reprod. 2009 Apr;24(4):835-41
19136478
Fertil Steril. 2009 Jan;91(1):32-9
18367178
J Pain. 2003 Sep;4(7):372-80
14622679
Fertil Steril. 2006 Dec;86(6):1561-72
17056043
Fertil Steril. 2002 Oct;78(4):767-72
12372454
Biol Reprod. 2002 May;66(5):1505-14
11967217
Hum Reprod. 2002 Jul;17(7):1895-900
12093857
Fertil Steril. 2006 Sep;86(3):711-5
16782099
Obstet Gynecol. 1992 May;79(5 ( Pt 1)):743-6
1565359
Pancreatology. 2004;4(6):551-9; discussion 559-60
15550764
J Vis Exp. 2012 Dec 21;(70):null
23288271
J Minim Invasive Gynecol. 2006 Jul-Aug;13(4):342-4
16825079
Semin Reprod Endocrinol. 1997;15(3):251-61
9383834
N Engl J Med. 2009 Jan 15;360(3):268-79
19144942
Hum Reprod. 2000 Jan;15(1):4-7
10611178