Complete genome sequence of Bacillus thuringiensis serovar alesti BGSC 4C1, a typical strain with toxicity to Lepidoptera insects.
Bacillus thuringiensis serovar alesti was used to control caterpillars from 1970s. Here we reported the complete genome of BGSC 4C1, the type strain of this serovar. It has a circular chromosome and six plasmids. The largest plasmid pBMB267 contains five insecticidal crystal protein genes (two copies of cry1Ae, cry1Gb, cry2Ab, and a novel cry1M-type gene) and three vegetative insecticidal protein genes (a novel binary toxin gene operon vip1-vip2 and vip3Aa). Besides, the strain also has many genes encodeing virulence factors, and some secondary metabolite biosynthetic gene clusters involved in synthesis of antimicrobial peptides and bacteriocins. In addition, there is a poly γ-glutamate synthesis gene cluster, whose product is a candidate to control inflammasome-mediated disorders and potential in many other fields.
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Yueying
Y
Wang
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Jingjing
J
Fu
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Qian
Q
Zhu
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Lei
L
Zhu
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Jinshui
J
Zheng
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Hualin
H
Liu
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Donghai
D
Peng
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China.
Lifang
L
Ruan
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, Hubei, People's Republic of China. Electronic address: m98sun@mail.hzau.edu.cn.
Ming
M
Sun
D001413:Bacillus thuringiensis / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics; D061046:Biological Control Agents; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D016680:Genome, Bacterial / Q000235:genetics*; D007306:Insecticides; D010957:Plasmids; D017422:Sequence Analysis, DNA
D001426:Bacterial Proteins; D061046:Biological Control Agents; D004269:DNA, Bacterial; D007306:Insecticides
Alesti serovariety; Bacillus thuringiensis; Complete genome; Lepidoptera