Aggressive cervical neuroblastoma with a rare paraneoplastic syndrome: A therapeutic dilemma.
Neuroblastoma is infrequently associated with paraneoplastic syndromes. Amongst the few, opsomyoclonus (Kinsbourne syndrome) is the most common neurological paraneoplastic syndrome and diarrhea secondary to increased secretion of vasoactive intestinal peptide (Kerner-Morrison syndrome), hormonal paraneoplastic syndrome. Hypothalamic dysfunction (HD) is a rare disorder and its manifestation as a paraneoplastic syndrome of neuroblastoma is uncommonly reported. We present an interesting case of an unrelenting cervical neuroblastoma associated with HD, which posed a therapeutic challenge.
Department of Pediatric Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
Sajid S
SS
Qureshi
Department of Pediatric Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
Monica
M
Bhagat
Department of Pediatric Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
Jay
J
Anam
Department of Pediatric Oncology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
Tushar
T
Vora
Cervical; hypothalamic dysfunction; neuroblastoma; paraneoplastic syndrome
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