Subjective experience of inner speech in aphasia: Preliminary behavioral relationships and neural correlates.
Many individuals with aphasia describe anomia with comments like "I know it but I can't say it." The exact meaning of such phrases is unclear. We hypothesize that at least two discrete experiences exist: the sense of (1) knowing a concept, but failing to find the right word, and (2) saying the correct word internally but not aloud (successful inner speech, sIS). We propose that sIS reflects successful lexical access; subsequent overt anomia indicates post-lexical output deficits. In this pilot study, we probed the subjective experience of anomia in 37 persons with aphasia. Self-reported sIS related to aphasia severity and phonological output deficits. In multivariate lesion-symptom mapping, sIS was associated with dorsal stream lesions, particularly in ventral sensorimotor cortex. These preliminary results suggest that people with aphasia can often provide meaningful insights about their experience of anomia and that reports of sIS relate to specific lesion locations and language deficits.
Department of Neurology, Georgetown University, Washington, DC, United States. Electronic address: mef231@georgetown.edu.
Mackenzie E
ME
Fama
Department of Neurology, Georgetown University, Washington, DC, United States.
William
W
Hayward
Department of Neurology, Georgetown University, Washington, DC, United States.
Sarah F
SF
Snider
Department of Neurology, Georgetown University, Washington, DC, United States.
Rhonda B
RB
Friedman
Department of Neurology, Georgetown University, Washington, DC, United States; Research Division, MedStar National Rehabilitation Hospital, Washington, DC, United States.
Peter E
PE
Turkeltaub
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000849:Anomia / Q000150:complications / Q000473:pathology / Q000503:physiopathology* / Q000523:psychology*; D001037:Aphasia / Q000150:complications / Q000473:pathology / Q000503:physiopathology* / Q000523:psychology*; D005260:Female; D006801:Humans; D007807:Language Tests; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D057566:Self Report; D066191:Sensorimotor Cortex / Q000473:pathology / Q000503:physiopathology; D013060:Speech
Anomia; Aphasia; Inner speech; Language; Lesion-symptom mapping; Self-report; Stroke
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