South-east Asian Zika virus strain linked to cluster of cases in Singapore, August 2016.
Zika virus (ZIKV) is an ongoing global public health emergency with 70 countries and territories reporting evidence of ZIKV transmission since 2015. On 27 August 2016, Singapore reported its first case of local ZIKV transmission and identified an ongoing cluster. Here, we report the genome sequences of ZIKV strains from two cases and find through phylogenetic analysis that these strains form an earlier branch distinct from the recent large outbreak in the Americas.
Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore.
Sebastian
S
Maurer-Stroh
Tze-Minn
TM
Mak
Yi-Kai
YK
Ng
Shiau-Pheng
SP
Phuah
Roland G
RG
Huber
Jan K
JK
Marzinek
Daniel A
DA
Holdbrook
Raphael Tc
RT
Lee
Lin
L
Cui
Raymond Tp
RT
Lin
D001210:Asia, Southeastern / Q000453:epidemiology; D016000:Cluster Analysis; D004196:Disease Outbreaks; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D058974:Phylogeography; D011634:Public Health; D012367:RNA, Viral / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D012846:Singapore; D000071244:Zika Virus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D000071243:Zika Virus Infection / Q000635:transmission / Q000821:virology
D012367:RNA, Viral
Flaviviridae, viral infections; Singapore; Zika virus; outbreaks; surveillance; vector-borne infections
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