Assessment of the extent of microcalcifications to predict the size of a ductal carcinoma in situ: comparison between tomosynthesis and conventional mammography.
OBJECTIVE
The objective was to determine if digital tomosynthesis of the breast (DBT) assesses the extension of ductal carcinoma in situ (DCIS) with higher precision than mammography (MG).


METHODS
The local ethics committee approved this retrospective study including 26 patients with DCIS, which were rated by three radiologists. Statistics were performed using intraclass correlation (ICC) for interreader agreement and the Pearson correlation for correlation of MG and DBT. Standard of reference was the histologic extension.


RESULTS
The ICC was excellent. Correlation between MG and histology was 0.879 (P<.01) and for DBT and histology was 0.914 (P<.01).


CONCLUSIONS
DBT provides a slightly better estimation of the size of a DCIS than MG.
Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland; Breast Center Zurich, Seefeldstrasse 214, 8008 Zurich, Switzerland. Electronic address: nicole.berger@usz.ch.
Nicole
N
Berger
Breast Center Zurich, Seefeldstrasse 214, 8008 Zurich, Switzerland. Electronic address: s.dubach@brustzentrum.ch.
Sibylle Dubach
SD
Schwizer
Institute of Surgical Pathology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: zsuzsanna.varga@usz.ch.
Zsuzsanna
Z
Varga
Breast Center Zurich, Seefeldstrasse 214, 8008 Zurich, Switzerland. Electronic address: c.rageth@brust-zentrum.ch.
Christoph
C
Rageth
Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: thomas.frauenfelder@usz.ch.
Thomas
T
Frauenfelder
Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: andreas.boss@usz.ch.
Andreas
A
Boss
D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008327:Mammography / Q000379:methods*; D008875:Middle Aged; D012189:Retrospective Studies
Breast; DCIS; Mammography; Microcalcification; Tomosynthesis