The Actin Cortex: A Bridge between Cell Shape and Function.
The cortical actin network controls many animal cell shape changes by locally modulating cortical tension. Recent work has provided insight into cortex components and regulators. However, how the network is reorganized in response to cellular signaling, and the role reorganization may play during cell state changes, remain to be determined.
Wellcome Trust/Medical Research Council Stem Cell Institute, University of Cambridge CB2 1QR, Cambridge, UK. Electronic address: kc370@cam.ac.uk.
Kevin J
KJ
Chalut
MRC-LMCB, University College London WC1E 6BT, London, UK; Institute for the Physics of Living Systems, University College London WC1E 6BT, London, UK. Electronic address: e.paluch@ucl.ac.uk.
Ewa K
EK
Paluch
D008841:Actin Cytoskeleton / Q000235:genetics* / Q000378:metabolism; D000199:Actins / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D048430:Cell Shape / Q000235:genetics; D006801:Humans; D009024:Morphogenesis / Q000235:genetics*; D015398:Signal Transduction
D000199:Actins