Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature.
We report a rare case of diffuse large B-cell lymphoma (DLBCL) of the lacrimal sac in a 50-year-old male. The incidence of primary ocular lymphoma is low and it is considered a rare disease. Moreover, reports of ocular DLBCL are uncommon and the disease remains poorly characterized. Our patient presented for management of osteomyelitis and was incidentally found to have a painless swelling and cyst around his right eye. A PET/CT scan revealed hypermetabolic activity within the lacrimal sac and a subsequent excisional biopsy of the mass yielded histopathology consistent with DLBCL. Consequently, the patient underwent treatment with R-CHOP therapy. The patient responded well to chemotherapy with a substantial shrinkage in tumor burden and the disease remained localized. Herein, we present a rare case of primary ocular lymphoma, highlight the importance of early diagnosis, and review current treatment modalities.
Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USA.
Kevin
0000-0002-9351-2317
K
Zarrabi
Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USA.
Ved
0000-0003-0772-4354
V
Desai
Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USA.
Brandom
B
Yim
Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USA.
Theodore G
TG
Gabig
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