Application of Traditional Chinese Medical Herbs in Prevention and Treatment of Respiratory Syncytial Virus.
Respiratory syncytial virus (RSV) is a common viral pathogen of the lower respiratory tract, which, in the absence of effective management, causes millions of cases of severe illness per year. Many of these infections develop into fatal pneumonia. In a review of English and Chinese medical literature, recent traditional Chinese medical herb- (TCMH-) based progress in the area of prevention and treatment was identified, and the potential anti-RSV compounds, herbs, and formulas were explored. Traditional Chinese medical herbs have a positive effect on inhibiting viral attachment, inhibiting viral internalization, syncytial formation, alleviation of airway inflammation, and stimulation of interferon secretion and immune system; however, the anti-RSV mechanisms of TCMHs are complicated, which should be further investigated.
Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China; Institute of Pediatrics, The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Li Li
LL
Lin
Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China; Institute of Pediatrics, The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China; Jiangsu Engineering Research Center for Efficient Delivery System of TCM, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jin Jun
0000-0001-8079-7950
JJ
Shan
Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China; Institute of Pediatrics, The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Tong
T
Xie
Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China; Institute of Pediatrics, The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jian Ya
JY
Xu
Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China; Institute of Pediatrics, The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Cun Si
CS
Shen
Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China; Jiangsu Engineering Research Center for Efficient Delivery System of TCM, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Liu Qing
LQ
Di
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Jia Bin
JB
Chen
Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China; Institute of Pediatrics, The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China; Jiangsu Engineering Research Center for Efficient Delivery System of TCM, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Shou Chuan
0000-0002-5260-6130
SC
Wang
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