Effects of aqueous root extract of Carpolobia alba G. Don on sexual behaviour in adult male rats.
Several lines say that a number of natural products, mostly plant based, have been claimed to cure male sexual dysfunction. One of such botanicals is Carpolobia alba G. Don which is used in Cameroon to treat erectile dysfunction and related male sexual debilities. However, the traditional claim has not been scientifically tested. Thirty adult male rats (five groups of six animals) were orally treated daily with distilled water, sildenafil citrate (positive control), 75, 150, 300 mg/kg of C. alba G. Don roots aqueous extract. The erection and ejaculation properties were recorded on the first, seventh and fourteenth day of treatment by following copulation settings: number of erections (NE), mount frequency (MF), intromission frequency (IF), ejaculation frequency (EF), mount latency (ML), intromission latency (IL), ejaculation latency (EL), average interval of copulation (AIC) and post-ejaculatory interval (PEI). The extract resulted in an improvement of copulation parameters through significant reduction (p < .001) of PEI, ML and IL and significant increase (p < .001) in the NE, MF, IF, EF, EL and AIC. These results indicate a pro-erectile and pro-ejaculatory potential of aqueous root extract of this plant in male rats.
Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon.
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Kenmogne
Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon.
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B
Koloko
Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon.
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Hambe
Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde, Yaounde, Cameroon.
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Domkam
Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon.
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Ngaha Njila
Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon.
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Bend
Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon.
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Oundoum Oundoum
Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon. pmasso@yahoo.fr.
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Massoma Lembè
Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde, Yaounde, Cameroon.
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Dimo
D000818:Animals; D003307:Copulation / Q000187:drug effects; D004542:Ejaculation / Q000187:drug effects*; D008297:Male; D010410:Penile Erection / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots; D029608:Polygalaceae; D051381:Rats; D012726:Sexual Behavior, Animal / Q000187:drug effects*
D010936:Plant Extracts
Carpolobia alba G. Don; ejaculation; erectile dysfunction