A Randomised Clinical Trial to Compare Coaxial and Noncoaxial Techniques in Percutaneous Core Needle Biopsy of Renal Parenchyma.
OBJECTIVE
To compare the coaxial and noncoaxial techniques of renal parenchymal core needle biopsy.


METHODS
This is an institutional review board-approved randomised controlled trial comparing 83 patients (male, n = 49) who underwent renal parenchymal core biopsy with coaxial method and 83 patients (male, n = 40) with noncoaxial method. The rate of complications, the number of glomerular profiles, and the procedural time were evaluated in a comparison of the two methods. Correlation between the presence of renal parenchymal disease and the rate of complication was also evaluated.


RESULTS
The procedural time was significantly shorter in the coaxial technique (coaxial group, 5 ± 1 min; noncoaxial group, 14 ± 2 min; p < 0.001). The rates of complications for the coaxial method was significantly lower than the noncoaxial method (coaxial group, 10.8 %; noncoaxial group, 24.1 %; p = 0.025). There was no significant correlation between gender and the rate of complication. The number of glomerular profiles was significantly higher in patents who underwent renal biopsy with the coaxial method (coaxial group, 18.2 ± 9.1; noncoaxial group, 8.6 ± 5.5; p < 0.001). In the whole study population, the rate of complications was significantly higher in patients with a pathologic renal parenchyma compared to those with a normal parenchyma (19/71 vs. 10/95; p = 0.006).


CONCLUSIONS
Renal parenchymal biopsy using a coaxial needle is a faster and safer method with a lower rate of complications.
Department of Radiology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Ali
A
Babaei Jandaghi
Urology Research Center, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Mohammadkazem
M
Lebady
Urology Research Center, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Athar-Alsadat
AA
Zamani
Department of Community Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Abtin
A
Heidarzadeh
Urology Research Center, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Ali
A
Monfared
Department of Radiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. ramin_p2005@yahoo.com.
Ramin
R
Pourghorban
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
Coaxial; Complications; Image-guided biopsy; Kidney; Kidney glomerulus