Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation.
SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour.
Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
A L M J
0000-0002-9994-7602
AL
van der Knijff-van Dortmont
Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
M
0000-0002-4306-654X
M
Dirckx
Department of Obstetrics and Gynaecology, Erasmus University Medical Centre, Rotterdam, Netherlands.
J J
JJ
Duvekot
Department of Cardiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
J W
JW
Roos-Hesselink
Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
A
A
Gonzalez Candel
Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
C D
CD
van der Marel
Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
G P
0000-0002-6460-1994
GP
Scoones
Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
V F R
VF
Adriaens
Department of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
I J J
0000-0001-9233-6385
IJ
Dons-Sinke
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