Development and Validation of a Photonumeric Scale for Evaluation of Facial Skin Texture.
BACKGROUND
A validated scale is needed for objective and reproducible comparisons of facial skin roughness before and after aesthetic treatment in practice and in clinical studies.


OBJECTIVE
To describe the development and validation of the 5-point photonumeric Allergan Skin Roughness Scale.


METHODS
The scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each grade. The clinical significance of a 1-point score difference was evaluated in a review of image pairs representing varying differences in severity. Interrater and intrarater reliability was evaluated in a live-subject validation study (N = 290) completed during 2 sessions occurring 3 weeks apart.


RESULTS
A score difference of ≥1 point was shown to reflect a clinically meaningful difference (mean [95% confidence interval] absolute score difference 1.09 [0.96-1.23] for clinically different image pairs and 0.53 [0.38-0.67] for not clinically different pairs). Intrarater agreement between the 2 validation sessions was almost perfect (weighted kappa = 0.83). Interrater agreement was almost perfect during the second rating session (0.81, primary end point).


CONCLUSIONS
The Allergan Skin Roughness Scale is a validated and reliable scale for physician rating of midface skin roughness.
*Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut; †Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada; ‡Allergan plc, Irvine, California; §Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada; ‖Division of Dermatology, University of California at Los Angeles, Los Angeles, California; ¶UC Davis Medical Group, Sacramento, California; #Peloton Advantage, LLC, Parsippany, New Jersey.
Lisa
L
Donofrio
Alastair
A
Carruthers
Bhushan
B
Hardas
Diane K
DK
Murphy
Jean
J
Carruthers
Derek
D
Jones
Jonathan M
JM
Sykes
Lela
L
Creutz
Ann
A
Marx
Sara
S
Dill
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005145:Face; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010781:Photography; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D012867:Skin / Q000033:anatomy & histology / Q000473:pathology*; D055815:Young Adult
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