Recurrent complicated urinary tract infection due to rare pathogen Sphingomonas paucimobilis: contamination or real deal?
Sphingomonas paucimobilis is an aerobic, oxidase-positive, yellow-pigmented, non-fermentative, Gram-negative opportunistic pathogen that rarely causes infections in humans. It is commonly found in nosocomial environments and, despite its low clinical virulence, it can be responsible for several different infections especially among patients with underlying disease. Here we describe a clinical case of a 46-year-old male paraplegic patient with a history of neurogenic bladder due to insulin-dependent diabetes mellitus and renal failure who was admitted to the urology clinic of a university hospital in Kirsehir, Turkey, with the complaints of urinary tract infection (UTI) including fever, chills, dysuria, abdominal and back pain. The urine culture was positive for Sphingomonas paucimobilis identified by the Vitek-2 system and the patient was successfully treated with oral co-trimoxazole 800/160 mg twice a day for ten days associated to cefixime and fosfomycin. A literature review of UTIs associated to Sphingomonas paucimobilis is reported as well.
Ahi Evran University Research and Training Hospital, Microbiology Department, Kirsehir, Turkey; Public Health Institution of Turkey, National Reference Laboratories of Microbiology, ara, Turkey.
Tulin
T
Demir
Ahi Evran University Research and Training Hospital, Urology Department, Kirsehir, Turkey.
Mumtaz
M
Dadali
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D020682:Cefixime / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000382:microbiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003928:Diabetic Nephropathies / Q000150:complications; D004198:Disease Susceptibility; D004359:Drug Therapy, Combination; D005578:Fosfomycin / Q000627:therapeutic use; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000453:epidemiology / Q000382:microbiology*; D010264:Paraplegia / Q000150:complications; D012008:Recurrence; D020578:Sphingomonas / Q000187:drug effects / Q000302:isolation & purification* / Q000472:pathogenicity; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D014421:Turkey / Q000453:epidemiology; D001750:Urinary Bladder, Neurogenic / Q000150:complications*; D014552:Urinary Tract Infections / Q000209:etiology / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D005578:Fosfomycin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D020682:Cefixime