Neuroticism and Fatigue 3 Months After Ischemic Stroke: A Cross-Sectional Study.
To examine the relation between neuroticism and fatigue in Chinese patients with stroke.



Cross-sectional study.



Acute stroke unit.



Survivors of ischemic stroke (N=191) recruited from the acute stroke unit between May 1, 2010, and September 1, 2011.



Not applicable.



The personality trait of neuroticism was measured with the neuroticism subscale of the Chinese version of the NEO Five-Factor Inventory. The level of fatigue was measured with the Fatigue Assessment Scale. The National Institutes of Health Stroke Scale, Geriatric Depression Scale, Barthel Index, and Mini-Mental State Examination were administered to obtain demographic and clinical information.



Fatigue severity 3 months after stroke positively correlated with Geriatric Depression Scale and NEO Five-Factor Inventory neuroticism scores and negatively correlated with the Barthel Index score.



Neuroticism, independent of depressive symptoms, is a predictor of fatigue severity 3 months after stroke. Interventions such as psychological screening programs are warranted for early detection of patients at high risk of poststroke depression.
Department of Psychiatry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Chieh Grace
CG
Lau
Department of Psychiatry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong. Electronic address: tangwk@cuhk.edu.hk.
Wai Kwong
WK
Tang
Department of Psychiatry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Xiang Xin
XX
Liu
Department of Psychiatry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Hua Jun
HJ
Liang
Department of Psychiatry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Yan
Y
Liang
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Vincent
V
Mok
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Adrian
A
Wong
School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Perth, Australia; The University of Notre Dame Australia/Marian Center, Perth, Australia.
Gabor S
GS
Ungvari
Department of Neurology, G.G. Kuvatov's Republican Clinical Hospital, Ufa, Russia.
Mansur A
MA
Kutlubaev
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Ka Sing
KS
Wong
D000368:Aged; D001008:Anxiety Disorders / Q000209:etiology* / Q000523:psychology*; D005221:Fatigue / Q000209:etiology* / Q000523:psychology*; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D000075384:Neuroticism; D012307:Risk Factors; D020521:Stroke / Q000150:complications* / Q000523:psychology*; D013997:Time Factors
Fatigue; Neuroticism; Personality; Rehabilitation; Stroke