Sleep Disorders, Restless Legs Syndrome, and Uremic Pruritus: Diagnosis and Treatment of Common Symptoms in Dialysis Patients.
Maintenance dialysis patients experience a high burden of physical and emotional symptoms that directly affect their quality of life and health care utilization. In this review, we specifically highlight common troublesome symptoms affecting dialysis patients: insomnia, restless legs syndrome, and uremic pruritus. Epidemiology, pathophysiology, and evidence-based current treatment are reviewed with the goal of providing a guide for diagnosis and treatment. Finally, we identify multiple additional areas of further study needed to improve symptom management in dialysis patients.
Division of Palliative Care, NYU School of Medicine, New York, NY; Division of Nephrology, NYU School of Medicine, New York, NY. Electronic address: jennifer.scherer@nyumc.org.
Jennifer S
JS
Scherer
Division of Nephrology, Department of Medicine, VA Eastern Colorado Health Care System, University of Colorado School of Medicine, Denver, CO; Division of Palliative Care, Department of Medicine, VA Eastern Colorado Health Care System, University of Colorado School of Medicine, Denver, CO.
Sara A
SA
Combs
Department of Nephrology, St. George Hospital, Kogarah, New South Wales, Australia.
Frank
F
Brennan
D000368:Aged; D006801:Humans; D008297:Male; D011537:Pruritus / Q000209:etiology* / Q000628:therapy; D006435:Renal Dialysis / Q000009:adverse effects*; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012893:Sleep Wake Disorders / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014511:Uremia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
Sleep disorders; chronic renal failure; dialysis; end-stage renal disease (ESRD); insomnia; kidney disease; quality of life (QoL); restless legs syndrome; review; symptom management; symptoms; uremic pruritus
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