Abiotic stress miRNomes in the Triticeae.
The continued growth in world population necessitates increases in both the quantity and quality of agricultural production. Triticeae members, particularly wheat and barley, make an important contribution to world food reserves by providing rich sources of carbohydrate and protein. These crops are grown over diverse production environments that are characterized by a range of environmental or abiotic stresses. Abiotic stresses such as drought, heat, salinity, or nutrient deficiencies and toxicities cause large yield losses resulting in economic and environmental damage. The negative effects of abiotic stresses have increased at an alarming rate in recent years and are predicted to further deteriorate due to climate change, land degradation, and declining water supply. New technologies have provided an important tool with great potential for improving crop tolerance to the abiotic stresses: microRNAs (miRNAs). miRNAs are small regulators of gene expression that act on many different molecular and biochemical processes such as development, environmental adaptation, and stress tolerance. miRNAs can act at both the transcriptional and post-transcriptional levels, although post-transcriptional regulation is the most common in plants where miRNAs can inhibit the translation of their mRNA targets via complementary binding and cleavage. To date, expression of several miRNA families such as miR156, miR159, and miR398 has been detected as responsive to environmental conditions to regulate stress-associated molecular mechanisms individually and/or together with their various miRNA partners. Manipulation of these miRNAs and their targets may pave the way to improve crop performance under several abiotic stresses. Here, we summarize the current status of our knowledge on abiotic stress-associated miRNAs in members of the Triticeae tribe, specifically in wheat and barley, and the miRNA-based regulatory mechanisms triggered by stress conditions. Exploration of further miRNA families together with their functions under stress will improve our knowledge and provide opportunities to enhance plant performance to help us meet global food demand.
Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, MT, USA.
Burcu
B
Alptekin
School of Agriculture, Food and Wine, University of Adelaide, Adelaide, Australia.
Peter
P
Langridge
Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, MT, USA. hikmet.budak@montana.edu.
Hikmet
http://orcid.org/0000-0002-2556-2478
H
Budak
D001467:Hordeum / Q000235:genetics*; D035683:MicroRNAs / Q000235:genetics*; D013312:Stress, Physiological / Q000235:genetics*; D014908:Triticum / Q000235:genetics*
D035683:MicroRNAs
Abiotic stress; Barley; Drought; Wheat; miRNA
Plant Mol Biol. 2013 Nov;83(4-5):433-43
23864359
RNA. 2008 May;14(5):836-43
18356539
Plant Cell. 2008 Aug;20(8):2238-51
18682547
PLoS One. 2007 Feb 14;2(2):e219
17299599
EMBO J. 2009 Dec 2;28(23):3646-56
19816405
Nucleic Acids Res. 2013 Apr;41(8):4470-80
23470996
J Exp Bot. 2009;60(6):1537-53
19386614
Int J Genomics. 2014;2014:701596
24804192
Genetics. 2008 Nov;180(3):1275-88
18757930
Plant J. 2013 Dec;76(6):1030-44
24164652
Int J Mol Sci. 2012;13(3):2973-2984
22489137
Genetics. 2011 Aug;188(4):883-96
21625003
Plant Cell. 2006 Aug;18(8):2051-65
16861386
Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19683-8
22106253
Funct Integr Genomics. 2015 May;15(3):323-48
25480755
Mol Biol Rep. 2014 Jul;41(7):4623-9
24682922
Nat Rev Genet. 2013 Feb;14(2):100-12
23329111
Funct Integr Genomics. 2017 May;17(2-3):171-187
27032785
BMC Plant Biol. 2013 Dec 13;13:214
24330740
Mol Plant. 2014 Aug;7(8):1329-1349
24821718
Plant Cell Rep. 2006 Dec;25(12):1263-74
16858552
Plant Cell. 2007 Aug;19(8):2417-29
17704216
BMC Plant Biol. 2012 Nov 07;12:209
23134682
Mol Plant. 2013 Mar;6(2):423-43
23264558
New Phytol. 2014 Jun;202(4):1197-1211
24533947
J Exp Bot. 2012 Jan;63(2):1025-38
22025521
RNA. 2008 May;14(5):814-21
18367716
Physiol Mol Biol Plants. 2013 Jul;19(3):307-21
24431500
Front Plant Sci. 2014 Apr 22;5:151
24795738
Science. 2010 May 14;328(5980):872-5
20413459
Planta. 2011 Mar;233(3):471-84
21069383
J Exp Bot. 2011 Mar;62(5):1611-20
21357774
Biochim Biophys Acta. 2012 Feb;1819(2):120-8
21964328
J Exp Bot. 2011 Aug;62(12):4367-81
21610018
Trends Cell Biol. 2014 Apr;24(4):212-20
24231398
Plant Mol Biol. 2013 Sep;83(1-2):89-103
23443681
Curr Biol. 2005 Aug 23;15(16):1501-7
16111943
PLoS One. 2012;7(11):e48951
23155433
Plant Physiol. 2013 Jan;161(1):362-73
23154535
Food Chem. 2013 Feb 15;136(3-4):1470-7
23194550
Cell. 2009 Feb 20;136(4):669-87
19239888
Curr Biol. 2010 Jan 12;20(1):42-8
20015654
Science. 2011 Sep 2;333(6047):1311-4
21885785
Science. 2010 Feb 12;327(5967):818-22
20150489
J Exp Bot. 2015 Aug;66(15):4653-67
26002970
Curr Biol. 2010 Mar 23;20(6):506-12
20226671
Biomed Res Int. 2014;2014:303451
25243128
Genome Res. 2006 Apr;16(4):510-9
16520461
BMC Plant Biol. 2015 Jan 27;15:21
25623724
PLoS One. 2014 Jan 13;9(1):e84781
24454749
Plant Cell. 2013 Oct;25(10):3685-98
24104565
New Phytol. 2012 Sep;195(4):766-773
22846054
BMC Plant Biol. 2011 Nov 17;11:163
22094046
Curr Biol. 2011 Oct 11;21(19):1678-83
21962713
Curr Biol. 2001 May 15;11(10):747-57
11378384
Plant Cell. 2013 May;25(5):1555-72
23695981
Plant Physiol Biochem. 2011 Mar;49(3):346-51
21296583
Annu Rev Plant Biol. 2006;57:19-53
16669754
Trends Plant Sci. 2014 Jun;19(6):371-9
24630845
PLoS One. 2015 Nov 12;10(11):e0142799
26562166
Science. 2000 Mar 31;287(5462):2494-7
10741970
PLoS One. 2015 Sep 15;10(9):e0137990
26372557
J Cell Physiol. 2012 Sep;227(9):3163-8
22252306
Science. 2012 Sep 14;337(6100):1360-1364
22984074
Mol Plant Pathol. 2014 Dec;15(9):907-17
24823923
Biosci Biotechnol Biochem. 2010;74(7):1435-40
20622450
J Exp Bot. 2015 Apr;66(7):1749-61
25697792
Sci China Life Sci. 2015 Nov;58(11):1057-66
26563174
PLoS One. 2012;7(9):e41143
22984395
Plant Cell. 1991 Jul;3(7):719-35
1841726
PLoS One. 2012;7(7):e40859
22815845
Plant Cell Physiol. 2013 Dec;54(12):1931-50
24204022
Gene. 2011 Sep 1;483(1-2):22-8
21635942
Nucleic Acids Res. 2012 Jul;40(13):6241-54
22434877
BMC Biol. 2011 Nov 17;9:79
22093487
BMC Plant Biol. 2012 Nov 21;12:220
23171309
Front Plant Sci. 2015 Jul 22;6:542
26257752
BMC Plant Biol. 2010 Apr 13;10:64
20388194
Plant Cell. 2007 Mar;19(3):926-42
17400893
J Exp Bot. 2014 Nov;65(20):6123-35
25183744
Plant Physiol. 2013 Mar;161(3):1375-91
23292790
Planta. 2003 Nov;218(1):1-14
14513379
Dev Biol. 2006 Jan 1;289(1):3-16
16325172
Silence. 2010 Jun 09;1(1):12
20534119
Plant Sci. 2012 Jan;182:87-93
22118619
Front Plant Sci. 2015 Apr 24;6:267
25964789
Plant Physiol. 2012 Jun;159(2):721-38
22508932
ScientificWorldJournal. 2013 Jun 06;2013:361921
23844392
Plant Sci. 2015 Sep;238:273-85
26259194
Funct Integr Genomics. 2015 Sep;15(5):523-31
26113396
PLoS One. 2014 Mar 26;9(3):e92456
24671003
Plant Signal Behav. 2013 Mar;8(3):e23488
23333957
RNA. 2008 Dec;14(12):2455-9
18952822
Plant J. 2014 Feb;77(3):367-79
24274116
PLoS One. 2012;7(12):e50261
23227161
Curr Opin Biotechnol. 2015 Apr;32:130-135
25531270
New Phytol. 2014 Apr;202(1):270-286
24383411
Nature. 2010 Mar 25;464(7288):628-32
20208518
J Plant Physiol. 2011 Sep 15;168(14):1685-93
21665325
Plant Physiol Biochem. 2016 Apr;101:60-67
26854408
J Nucleic Acids. 2014;2014:570176
25180085
Appl Biochem Biotechnol. 2015 Nov;177(6):1299-312
26315134
Front Plant Sci. 2015 Apr 10;6:232
25914709
Nature. 2012 Nov 29;491(7426):711-6
23075845
Plant Cell Rep. 2010 Aug;29(8):835-44
20490502
Plant Physiol Biochem. 2014 Jul;80:90-6
24735552
Funct Integr Genomics. 2009 Aug;9(3):377-96
19330365
Physiol Mol Biol Plants. 2012 Oct;18(4):287-300
24082491
Plant Physiol. 2011 Jul;156(3):1016-24
21562333
BMC Plant Biol. 2011 Jan 10;11:5
21219599
Plant Cell. 2000 Dec;12(12):2351-2366
11148283
Gene. 2015 Jan 25;555(2):178-85
25445264
Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15594-8
19717432
Plant Mol Biol. 2013 Apr;81(6):525-39
23430564
Plant Cell. 2011 Apr;23(4):1249-63
21467582
Plant Physiol. 2011 Aug;156(4):2053-68
21653783
Genomics Proteomics Bioinformatics. 2014 Apr;12(2):64-71
24769055
Plant Cell Environ. 2009 Mar;32(3):220-36
19054353
Biol Direct. 2012 May 08;7:15
22569316
Curr Opin Cell Biol. 2009 Jun;21(3):367-76
19243928
Phytochemistry. 2015 Apr;112:122-9
25027646
Nat Rev Genet. 2007 Apr;8(4):272-85
17363976
PLoS One. 2012;7(11):e48445
23133634
New Phytol. 2013 Dec;200(4):1102-15
23915383
Genet Mol Res. 2013 Oct 07;12(4):4213-21
24114216
Front Plant Sci. 2015 Nov 19;6:1012
26635838
Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8795-800
18550839
Trends Plant Sci. 2015 Jan;20(1):33-40
25153038
Cell. 2005 Apr 22;121(2):207-21
15851028
RNA Biol. 2014;11(9):1099-104
25483033
J Exp Bot. 2014 May;65(8):2119-35
24604734
Plant Cell. 2014 Apr 11;26(4):1764-1780
24728648
J Exp Bot. 2012 Oct;63(16):5903-18
22962679
BMC Genomics. 2009 Dec 30;10:643
20042113
Nature. 2010 May 20;465(7296):316-21
20410882
Plant Sci. 2015 Jun;235:1-13
25900561
Plant Signal Behav. 2010 Aug;5(8):995-8
20724818
Genomics Inform. 2014 Dec;12(4):261-7
25705168
Science. 2004 Mar 12;303(5664):1626-32
15016989
Plant Physiol. 2010 Aug;153(4):1859-70
20498336
Nat Rev Genet. 2015 Apr;16(4):237-51
25752530
Annu Rev Plant Biol. 2013;64:137-59
23330790
Plant J. 2015 Aug;83(4):673-85
26096676
Plant Cell. 2012 Dec;24(12):4777-92
23275578
Plant Cell Environ. 2015 Nov;38(11):2195-207
25392907
Brief Funct Genomics. 2016 Jan;15(1):65-71
26148500
J Exp Bot. 2002 Jan;53(366):1-11
11741035
Cell. 2009 Feb 6;136(3):461-72
19203581
Int J Mol Sci. 2013 May 03;14(5):9643-84
23644891
BMC Genomics. 2007 Jul 18;8:242
17640358
Front Plant Sci. 2015 Jan 21;6:5
25653665
New Phytol. 2013 Aug;199(3):639-49
24010138
Curr Opin Biotechnol. 2015 Apr;32:113-120
25528276
Front Plant Sci. 2016 May 04;7:606
27200073
Plant Cell. 2013 Jul;25(7):2383-99
23881412
Cell. 2012 Sep 28;151(1):194-205
23000270
Plant J. 1999 Oct;20(1):89-99
10571868
PLoS One. 2011 May 03;6(5):e19212
21559273
Plant Cell Physiol. 2008 Nov;49(11):1634-44
18829588
Planta. 2012 Oct;236(4):1081-92
22569921
Planta. 2010 Jan;231(2):449-59
19943170
Cell. 2002 Aug 23;110(4):513-20
12202040
Annu Rev Plant Biol. 2003;54:183-206
14509968
Funct Integr Genomics. 2017 May;17(2-3):237-251
27562677
Mol Cell. 2014 Dec 4;56(5):696-707
25454948
J Integr Plant Biol. 2014 Mar;56(3):192-220
24417933
Front Plant Sci. 2014 Sep 16;5:474
25278950
Plant Signal Behav. 2012 Nov;7(11):1450-5
22990453
Plant Physiol Biochem. 2007 Aug;45(8):521-34
17560114
Biochim Biophys Acta. 2012 Feb;1819(2):97-103
22037288
Mol Genet Genomics. 2014 Dec;289(6):1289-306
25098419
Funct Integr Genomics. 2014 Jun;14(2):363-79
24395439
New Phytol. 2007;173(4):677-702
17286818
Genes Dev. 2006 Dec 15;20(24):3407-25
17182867
Biochem Biophys Res Commun. 2010 Jul 30;398(3):355-60
20599742
Plant Biotechnol J. 2015 Jan;13(1):2-13
24975557
BMC Plant Biol. 2012 Jul 28;12:120
22838835
Int J Mol Sci. 2015 Jul 13;16(7):15811-51
26184177
Funct Integr Genomics. 2015 Sep;15(5):587-98
26174050
Trends Plant Sci. 2015 Feb;20(2):124-33
25499025
Plant Physiol Biochem. 2010 Feb-Mar;48(2-3):153-9
20097571
Planta. 2000 Sep;211(4):575-82
11030557
New Phytol. 2015 May;206(3):913-931
25605349
J Exp Bot. 2012 Jan;63(1):203-14
21934119
Trends Plant Sci. 2013 Nov;18(11):601-10
23993483
Plant J. 2012 May;70(3):432-44
22248025
Genetics. 2012 Nov;192(3):763-74
23135324
Environ Sci Pollut Res Int. 2015 Mar;22(6):4056-75
25398215
Nucleic Acids Res. 2015 Jan;43(1):607-17
25514924
Nat Genet. 2010 Jun;42(6):545-9
20495564
Front Plant Sci. 2013 Jul 31;4:273
23914193
Cell. 2009 Aug 21;138(4):750-9
19703400
ScientificWorldJournal. 2013 Nov 11;2013:610721
24319376
Plant Biotechnol J. 2015 Apr;13(3):293-305
25583362
Plant Cell. 2014 Apr 25;26(4):1792-1807
24769482
Plant Cell. 2009 Nov;21(11):3421-35
19903869
Mol Plant Pathol. 2014 Apr;15(3):284-96
24128392
J Exp Bot. 2011 Feb;62(4):1455-66
21239377
Front Plant Sci. 2013 Apr 05;4:80
23577017
New Phytol. 2015 Apr;206(1):422-435
25425527
Funct Integr Genomics. 2010 Nov;10(4):493-507
20676715
Biotechnol Lett. 2011 Feb;33(2):403-9
20960221
Trends Plant Sci. 2007 Feb;12(2):71-9
17224300
BMC Plant Biol. 2012 Oct 05;12:182
23040172
Plant J. 2014 Apr;78(1):44-55
24460537
BMC Genomics. 2015 Mar 17;16:197
25888374
ScientificWorldJournal. 2013 May 15;2013:548246
23766697
PLoS One. 2014 Apr 18;9(4):e95489
24748226
OMICS. 2011 Nov;15(11):791-9
22122669
Nature. 2006 Aug 31;442(7106):1046-9
16892047
Brief Funct Genomics. 2015 May;14(3):189-98
24962995
DNA Res. 2013 Apr;20(2):109-25
23266877
Plant Mol Biol. 2013 May;82(1-2):113-29
23483290
Funct Integr Genomics. 2012 Nov;12(4):649-58
22585409
Nat Genet. 2004 Dec;36(12):1282-90
15565108