Expression of the insulinoma-associated 1 (insm1) gene in Xenopus laevis tadpole retina and brain.
The insulinoma-associated 1 (insm1) gene is involved in the differentiation of several neuronal and endoderm derived cell types. insm1 is expressed in the retina and brain of several vertebrates including Xenopus laevis. We report the detailed expression pattern of insm1 in the X. laevis tadpole retina and brain. X. laevis insm1 is expressed in most of the ciliary marginal zone of the mature retina and the optic tectum, dorsal pallium, hypothalamus and preoptic areas of the developing tadpole brain. Overall, insm1 is expressed in regions of the tadpole brain and retina harboring populations of progenitor cells.
Graduate Program in Molecular, Cellular, and Developmental Biology, College of Biological Sciences, Ohio State University, Columbus, OH, USA.
Jennifer L
JL
Bosse
Graduate Program in Molecular, Cellular, and Developmental Biology, College of Biological Sciences, Ohio State University, Columbus, OH, USA; Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, College of Medicine, Ohio State University, Columbus, OH, USA. Electronic address: Heithem.El-Hodiri@NationwideChildrens.org.
Heithem M
HM
El-Hodiri
D000818:Animals; D001921:Brain / Q000254:growth & development* / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental / Q000235:genetics; D007814:Larva / Q000235:genetics / Q000254:growth & development; D012160:Retina / Q000254:growth & development* / Q000378:metabolism; D013234:Stem Cells / Q000378:metabolism; D014157:Transcription Factors / Q000096:biosynthesis* / Q000235:genetics; D029867:Xenopus Proteins / Q000096:biosynthesis* / Q000235:genetics; D014982:Xenopus laevis / Q000235:genetics* / Q000254:growth & development
C532313:INSM1 protein, Xenopus; D014157:Transcription Factors; D029867:Xenopus Proteins
Ciliary marginal zone; Dorsal pallium; Hypothalamus; Optic tectum; Xenopus laevis; insm1
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