Diagnostic Errors and Laboratory Medicine - Causes and Strategies.
While the frequency of laboratory errors varies greatly, depending on the study design and steps of the total testing process (TTP) investigated, a series of papers published in the last two decades drew the attention of laboratory professionals to the pre- and post-analytical phases, which currently appear to be more vulnerable to errors than the analytical phase. In particular, a high frequency of errors and risk of errors that could harm patients has been described in both the pre-pre- and post-post-analytical steps of the cycle that usually are not under the laboratory control. In 2008, the release of a Technical Specification (ISO/TS 22367) by the International Organization for Standardization played a key role in collecting the evidence and changing the perspective on laboratory errors, emphasizing the need for a patient-centred approach to errors in laboratory testing.
Department of Laboratory Medicine, University-Hospital , Padova, Italy.
Mario
M
Plebani
brain-to-brain loop; diagnostic errors; laboratory medicine; laboratory-associated errors; patient safety; quality
Ann Intern Med. 2005 Jul 19;143(2):121-8
16027454
BMJ Qual Saf. 2013 Aug;22(8):672-80
23610443
J Gen Intern Med. 2011 Apr;26(4):393-8
21116868
Arch Pathol Lab Med. 2005 Oct;129(10):1252-61
16196513
Am J Clin Pathol. 1947 Nov;17(11):853-61
20269991
Ann Emerg Med. 2007 Feb;49(2):196-205
16997424
Clin Chem. 2012 Mar;58(3):638-42
22205692
Clin Chem. 2007 Jul;53(7):1338-42
17525103
Clin Chem. 1997 Aug;43(8 Pt 1):1352-6
9267313
Am J Clin Pathol. 2009 Feb;131(2):195-204
19141380
Ann Clin Biochem. 2010 Mar;47(Pt 2):101-10
19952034
Arch Intern Med. 2009 Jun 22;169(12):1123-9
19546413
Arch Intern Med. 2005 Jul 11;165(13):1493-9
16009864
Clin Chim Acta. 2009 Jun;404(1):28-31
19302996
Clin Chem Lab Med. 2013 Jan;51(1):187-95
23023884
Ann Intern Med. 2006 Oct 3;145(7):488-96
17015866
Clin Chem Lab Med. 2014 Jul;52(7):951-8
24622792
Qual Saf Health Care. 2008 Jun;17(3):194-200
18519626
Clin Chim Acta. 2009 Jun;404(1):16-23
19302995
J Gen Intern Med. 2012 Oct;27(10):1334-48
22183961
Clin Chem Lab Med. 2013 Apr;51(4):741-51
23435100
Clin Chem. 1997 Aug;43(8 Pt 1):1348-51
9267312
JAMA Intern Med. 2013 Mar 25;173(6):418-25
23440149
Am J Clin Pathol. 2011 Dec;136(6):829-33
22095366
Arch Intern Med. 2005 Mar 14;165(5):574-7
15767535
BMJ Qual Saf. 2013 Oct;22 Suppl 2:ii6-ii10
23955467
Am J Med. 2000 Oct 15;109(6):494-7
11042241
Clin Chem Lab Med. 2011 May;49(5):835-44
21342024
Arch Pathol Lab Med. 1996 Dec;120(12):1094-101
15456173
BMC Fam Pract. 2007 May 22;8:32
17519017
Clin Chem Lab Med. 2013 Jan;51(1):39-46
23089538