Management of familial benign chronic pemphigus.
Benign familial chronic pemphigus or Hailey-Hailey disease is caused by an autosomal dominant mutation in theATP2C1gene leading to suprabasilar acantholysis. The disease most commonly affects intertriginous areas symmetrically. The chronic nature of the disease and multiple recurrences make the disease bothersome for patients and a treatment challenge for physicians. Treatments include topical and/or systemic agents and surgery including laser. This review summarizes the available treatment options.
Department of Dermatology and Cutaneous Surgery, University of Miami-Miller School of Medicine, Miami, FL, USA.
Harleen
H
Arora
Department of Dermatology and Cutaneous Surgery, University of Miami-Miller School of Medicine, Miami, FL, USA.
Fleta N
FN
Bray
Department of Dermatology and Cutaneous Surgery, University of Miami-Miller School of Medicine, Miami, FL, USA.
Jessica
J
Cervantes
Department of Dermatology and Cutaneous Surgery, University of Miami-Miller School of Medicine, Miami, FL, USA.
Leyre A
LA
Falto Aizpurua
Hailey–Hailey disease; corticosteroids; dermabrasion; familial benign chronic pemphigus; laser
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