Economic and care considerations of Marfan syndrome.
Marfan syndrome is a rare multisystem disease of the connective tissue, which affects multiple organ systems. advances in healthcare have doubled the life-expectancy of patients over the past three decades. to date, there is no comprehensive review that consolidates economic considerations and care for marfan patients. Areas covered: Present research suggests that there may be a link between treatment pattern, disease progression and economic costs of Marfan syndrome. It indicates that an early detection of the disease and preventive interventions achieve a dual aim. From a patient perspective, it may reduce the amount of emergency surgery or intervention, and inpatient stays. In addition, it slows disease progression, lowers lifestyle restrictions, reduces psychological stress, and improves health-related quality of life. Expert commentary: Early detection and preventive measures are likely to achieve a dual aim by simultaneously containing costs and reducing the number and length of inpatient stays.
a Hamburg Center for Health Economics , Universität Hamburg , Hamburg , Germany.
Carl Rudolf
CR
Blankart
a Hamburg Center for Health Economics , Universität Hamburg , Hamburg , Germany.
Ricarda
R
Milstein
b University Heart Center Hamburg , University Hospital Eppendorf , Hamburg , Germany.
Meike
M
Rybczynski
b University Heart Center Hamburg , University Hospital Eppendorf , Hamburg , Germany.
Helke
H
Schüler
b University Heart Center Hamburg , University Hospital Eppendorf , Hamburg , Germany.
Yskert
Y
von Kodolitsch
D018450:Disease Progression; D017048:Health Care Costs; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007902:Length of Stay; D008017:Life Expectancy; D008019:Life Style; D008382:Marfan Syndrome / Q000191:economics / Q000503:physiopathology / Q000628:therapy*; D011788:Quality of Life; D013315:Stress, Psychological / Q000209:etiology
FBN1; Loeys-Dietz syndrome; Marfan syndrome; TGFBR2; costs; decision-making; economy; gene; healthcare; surgery