The Olfactory Mosaic: Bringing an Olfactory Network Together for Odor Perception.
Olfactory perception and its underlying neural mechanisms are not fixed, but rather vary over time, dependent on various parameters such as state, task, or learning experience. In olfaction, one of the primary sensory areas beyond the olfactory bulb is the piriform cortex. Due to an increasing number of functions attributed to the piriform cortex, it has been argued to be an associative cortex rather than a simple primary sensory cortex. In fact, the piriform cortex plays a key role in creating olfactory percepts, helping to form configural odor objects from the molecular features extracted in the nose. Moreover, its dynamic interactions with other olfactory and nonolfactory areas are also critical in shaping the olfactory percept and resulting behavioral responses. In this brief review, we will describe the key role of the piriform cortex in the larger olfactory perceptual network, some of the many actors of this network, and the importance of the dynamic interactions among the piriform-trans-thalamic and limbic pathways.
Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Department of Child and Adolescent Psychiatry, New York University Langone Medical Center, New York, NY, USA.
Emmanuelle
E
Courtiol
Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Department of Child and Adolescent Psychiatry, New York University Langone Medical Center, New York, NY, USA.
Donald A
DA
Wilson
D006801:Humans; D008032:Limbic System / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D009833:Olfactory Pathways / Q000502:physiology*; D055696:Olfactory Perception / Q000502:physiology*; D066195:Piriform Cortex / Q000502:physiology*; D013788:Thalamus / Q000502:physiology*
limbic connection; network; odor; olfactory perception; piriform cortex; thalamocortical
Behav Neural Biol. 1994 Jan;61(1):1-18
7907468
Chem Senses. 2001 Jun;26(5):551-76
11418502
J Neurosci. 2013 Aug 14;33(33):13449-59
23946403
Jpn J Physiol. 1984;34(1):55-73
6328081
J Neurosci. 2008 May 14;28(20):5257-67
18480282
J Comp Neurol. 1978 Apr 15;178(4):711-40
632378
J Neurophysiol. 2014 Mar;111(6):1274-85
24353302
Science. 1981 Oct 2;214(4516):91-2
7280684
Cereb Cortex. 2015 Jan;25(1):180-91
23960200
Front Psychol. 2013 Oct 16;4:743
24137148
Brain Res Rev. 2009 Dec 11;62(1):109-26
19800366
J Comp Neurol. 1977 Jan 15;171(2):157-91
64477
Eur J Neurosci. 2006 Apr;23 (7):1801-10
16623837
J Neurophysiol. 1997 Jun;77(6):3326-39
9212278
Front Neural Circuits. 2012 Sep 19;6:69
23049500
J Integr Neurosci. 2013 Jun;12(2):201-19
23869861
Brain Res. 1988 Feb 23;442(1):180-4
3359252
Nat Neurosci. 2011 Nov 20;15(1):155-61
22101640
Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15206-11
17005727
J Neurophysiol. 1995 Aug;74(2):733-50
7472378
Neurosci Lett. 2011 Jun 22;497(2):69-73
21530613
Front Neural Circuits. 2015 Sep 18;9:49
26441548
Brain Res. 1989 Jan 30;478(2):257-68
2924130
J Comp Neurol. 1984 Feb 20;223(2):177-202
6200518
J Neurophysiol. 2003 Dec;90(6):3921-30
12917385
Nat Neurosci. 2008 Dec;11(12 ):1378-80
18978781
Prog Brain Res. 2004;145:207-31
14650918
J Neurosci. 2011 Jun 1;31(22):8123-33
21632934
Neuroreport. 2007 May 7;18(7):683-8
17426599
Neuron. 2011 Oct 6;72 (1):41-8
21982367
Electroencephalogr Clin Neurophysiol. 1984 Mar;57(3):270-6
6199188
J Neurophysiol. 2012 Feb;107(4):1222-9
22131370
Nat Neurosci. 2016 Jul;19(7):935-44
27182817
Science. 2002 Jul 19;297(5580):359-65
12130775
Brain Behav Evol. 1980;17(4):276-90
7397487
Nat Neurosci. 2003 Feb;6(2):196-202
12536208
J Comp Neurol. 2003 Mar 17;457(4):361-73
12561076
Electroencephalogr Clin Neurophysiol Suppl. 1987;40:468-72
2826105
Nat Rev Neurosci. 2010 Sep;11(9):628-41
20700142
Brain Res. 1997 Aug 22;766(1-2):39-49
9359585
J Neurophysiol. 1998 Mar;79(3):1425-40
9497422
J Neurosci. 2007 Feb 14;27(7):1534-42
17301162
J Neurophysiol. 1960 Mar;23:111-31
13824765
Nature. 1998 Mar 19;392(6673):282-6
9521322
Nat Neurosci. 2013 Aug;16(8):991-3
23792942
Chem Senses. 2001 Jun;26(5):585-94
11418504
Behav Neurosci. 1991 Feb;105(1):111-9
2025384
Psychophysiology. 1982 Jan;19(1):44-56
7058239
J Neurophysiol. 2000 Jan;83(1):537-51
10634894
Soc Neurosci. 2017 Feb;12 (1):32-49
26934130
J Neurophysiol. 1998 Aug;80(2):998-1001
9705487
J Neurophysiol. 2010 Dec;104(6):3231-9
20861440
Neurosci Lett. 1999 Nov 26;276(1):17-20
10586964
Cereb Cortex. 2000 Mar;10(3):295-307
10731224
Nat Neurosci. 2009 Jul;12 (7):932-8
19483688
Brain Res. 1996 Feb 26;710(1-2):69-78
8963680
J Neurophysiol. 2011 Dec;106(6):3136-44
21918001
J Physiol. 2015 Apr 1;593(7):1701-14
25604039
Neuron. 2009 Jun 25;62(6):850-61
19555653
Brain Behav Evol. 1980;17(4):255-75
7397486
Neuron. 2009 Sep 24;63(6):854-64
19778513
Brain Res Bull. 1984 Jun;12(6):669-88
6206930
Cereb Cortex. 2007 Jun;17 (6):1342-9
16882682
Chem Senses. 2000 Oct;25(5):561-73
11015328
Eur J Neurosci. 2003 Jun;17 (11):2457-61
12814377
J Neurophysiol. 1992 May;67(5):1222-9
1597708
Behav Neurosci. 1996 Jun;110(3):443-50
8888989
Brain Res. 1977 Jun 24;129(1):152-7
68803
J Neurophysiol. 1980 Jan;43(1):69-85
6766180
J Neurobiol. 1996 May;30(1):123-76
8727988
Sci Am. 1991 Feb;264(2):78-85
2000483
Physiol Behav. 2002 Dec;77(4-5):489-93
12526988
Neuroscience. 2008 Oct 15;156(3):781-7
18790020
Neuron. 2011 Nov 17;72 (4):506-19
22099455
Prog Brain Res. 2014;208:253-74
24767486
Neuroreport. 1995 Jul 10;6(10):1377-80
7488728
Behav Neurosci. 1998 Jun;112(3):541-53
9676972
Science. 2008 Mar 28;319(5871):1842-5
18369149
Cereb Cortex. 2007 Mar;17 (3):643-52
16699083
Synapse. 2006 Mar 1;59(3):135-43
16342059
J Anat. 1971 Oct;110(Pt 1):105-26
5140514
J Neurosci. 2009 Aug 19;29(33):10287-98
19692603
Behav Brain Res. 1987 Aug;25(2):117-29
3675824
Nat Commun. 2016 May 04;7:11546
27143299
Nature. 2014 Nov 13;515(7526):269-73
25383519
J Comp Neurol. 2005 Jul 25;488(2):224-31
15924345
Brain Res. 1990 Aug 13;525(1):175-9
1978790
Front Behav Neurosci. 2014 Apr 22;8:134
24795585
J Neurophysiol. 1995 Aug;74(2):751-62
7472379
Neuron. 2006 Aug 17;51(4):495-507
16908414
J Comp Neurol. 2004 Aug 30;476(4):414-28
15282713
J Physiol Paris. 2004 Jul-Nov;98 (4-6):467-78
16274975
Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16931-6
25385630
J Neurophysiol. 2006 Mar;95(3):1888-96
16251260
Front Neural Circuits. 2015 Dec 21;9:81
26733819
J Neurosci. 2016 Jun 1;36(22):5946-60
27251617
J Comp Neurol. 1983 Mar 20;215(1):63-77
6853766
Chem Senses. 2005 Jun;30(5):401-19
15829609