A Closer Look at Fractional Flow Reserve in Complex Anatomic Subsets: Left Main Disease, Bifurcation Lesions, and Saphenous Vein Grafts.
Fractional flow reserve (FFR) is a well-validated tool for determining the functional significance of a coronary artery stenosis, facilitating clinical decisions regarding the need for revascularization. FFR-guided revascularization improves clinical and economic outcomes. However, its application remains challenging in certain complex anatomic subsets, including left main coronary artery stenosis, bifurcation disease, and saphenous vein graft disease. This article reviews recent data supporting the use of FFR in these complex anatomic subsets.
Cedars-Sinai Medical Center, Division of Cardiology, Los Angeles, CA.
David C
DC
Lange
University of California, Irvine and VA Long Beach, Irvine, CA.
Morton J
MJ
Kern
D001783:Blood Flow Velocity; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000503:physiopathology* / Q000601:surgery*; D023903:Coronary Restenosis / Q000503:physiopathology* / Q000601:surgery*; D003657:Decision Making; D053805:Fractional Flow Reserve, Myocardial; D006083:Graft Occlusion, Vascular / Q000503:physiopathology; D006801:Humans; D009204:Myocardial Revascularization / Q000379:methods*; D012501:Saphenous Vein / Q000637:transplantation*