Impaired Spatial Learning is Associated with Disrupted Integrity of the White Matter in Akt3 Knockout Mice.
State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
He
H
Wang
Department of Physiology, Nanjing Medical University, Nanjing, China.
Bao-Feng
BF
Zhang
Department of Physiology, Nanjing Medical University, Nanjing, China.
Ting-Ting
TT
Zhang
State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Long
L
Wang
State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Xiao-Yan
XY
Zou
Department of Neurology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu Province, China.
Yun
Y
Xu
Department of Physiology, Nanjing Medical University, Nanjing, China.
Ling
L
Chen
State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Gui-Quan
GQ
Chen
D000818:Animals; D007150:Immunohistochemistry; D018345:Mice, Knockout; D004676:Myelin Basic Protein / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt / Q000172:deficiency* / Q000235:genetics; D065853:Spatial Learning / Q000502:physiology*; D065852:Spatial Memory / Q000502:physiology; D066127:White Matter / Q000378:metabolism* / Q000473:pathology*
C499047:Mbp protein, mouse; D004676:Myelin Basic Protein; C514862:Akt1 protein, mouse; C491753:Akt3 protein, mouse; D051057:Proto-Oncogene Proteins c-akt
J Biol Chem. 2003 Aug 22;278(34):32124-31
12783884
Mol Cell Biol. 2005 Mar;25(5):1869-78
15713641
Development. 2005 Jul;132(13):2943-54
15930105
Cell. 2007 Jun 29;129(7):1261-74
17604717
Am J Hum Genet. 2007 Aug;81(2):292-303
17668379
J Neurosci. 2010 Sep 29;30(39):13066-77
20881124
J Pathol. 2011 Sep;225(1):54-62
21598254
Biochem Soc Trans. 2011 Aug;39(4):881-5
21787317
J Cereb Blood Flow Metab. 2015 Jun;35(6):1005-14
25669904
CNS Neurosci Ther. 2016 Mar;22(3):244-7
26804055