A noninvasive swallowing measurement system using a combination of respiratory flow, swallowing sound, and laryngeal motion.
The assessment of swallowing function is important for the prevention of aspiration pneumonia. We developed a new swallowing monitoring system that uses respiratory flow, swallowing sound, and laryngeal motion. We applied this device to 11 healthy volunteers and 10 patients with dysphagia. Videofluoroscopy (VF) was conducted simultaneously with swallowing monitoring using our device. We measured laryngeal rising time (LRT), the time required for the larynx to elevate to the highest position, and laryngeal activation duration (LAD), the duration between the onset of rapid laryngeal elevation and the time when the larynx returned to the lowest position. In addition, we evaluated the coordination between swallowing and breathing. We found that LAD was correlated with a VF-derived parameter, pharyngeal response duration (PRD) in healthy subjects (LAD: 959 ± 259 ms vs. PRD: 1062 ± 149 ms, r = 0.60); however, this correlation was not found in the dysphagia patients. LRT was significantly prolonged in patients (healthy subjects: 320 ± 175 ms vs.


METHODS
465 ± 295 ms, P < 0.001, t test). Furthermore, frequency of swallowing immediately after inspiration was significantly increased in patients. Therefore, the new device may facilitate the assessment of some aspects of swallowing dysfunction.
Department of Neurology, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan.|Clinical Research Center for Medical Equipment Development (CRCMeD), Kyoto University Hospital, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan.
Naomi
N
Yagi
Department of Neurology, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan.|Clinical Research Center for Medical Equipment Development (CRCMeD), Kyoto University Hospital, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan.|Department of Physiology, Division of Physiome, Hyogo College of Medicine, 1-1 Mukogawa-cho, Hyogo, Nishinomiya, 663-8501, Japan.
Shinsuke
S
Nagami
Department of Physiology, Division of Physiome, Hyogo College of Medicine, 1-1 Mukogawa-cho, Hyogo, Nishinomiya, 663-8501, Japan.
Meng-Kuan
MK
Lin
Murata Manufacturing Co., Ltd., 1-10-1, Higashikotari, Nagaokakyo, Kyoto, 617-8555, Japan.
Toru
T
Yabe
Wakakusa Tatsuma Rehabilitation Hospital, 1580 Oaza-tatsuma, Daito, Osaka, 574-0012, Japan.
Masataka
M
Itoda
Ashiya Municipal Hospital, 39-1 Asahigaoka-cho, Ashiya, Hyogo, 659-0012, Japan.
Takahisa
T
Imai
Department of Physiology, Division of Physiome, Hyogo College of Medicine, 1-1 Mukogawa-cho, Hyogo, Nishinomiya, 663-8501, Japan. yoku@hyo-med.ac.jp.
Yoshitaka
Y
Oku
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003679:Deglutition / Q000502:physiology*; D003680:Deglutition Disorders / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007830:Larynx / Q000502:physiology*; D008297:Male; D009038:Motion; D010614:Pharynx / Q000502:physiology*; D012123:Pulmonary Ventilation / Q000502:physiology*; D012119:Respiration; D013016:Sound
Coordination between swallowing and breathing; Deglutition apnea; Dysphagia; Swallowing
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