Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (EBUS-TBNA) for Diagnosis of Mediastinal and Hilar Masses.
OBJECTIVE
To determine the sensitivity, specificity, negative and positive predictive values, and diagnostic accuracy of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (EBUS-TBNA).


METHODS
Across-sectional validation study.


METHODS
Department of Histopathology, Army Medical College, in collaboration with Department of Pulmonology, Military Hospital Rawalpindi, from March 2014 to March 2015.


METHODS
Cases of EBUS-TBNAcomprised of both TBNAs and cell block/biopsy of the same patients. Diagnosis was made on the TBNAslides and cell block/biopsy material. Taking biopsy/cell block as the gold standard, the data was analysed to calculate the sensitivity, specificity, negative and positive predictive values, and diagnostic accuracy of EBUSTBNA.


RESULTS
The sensitivity of EBUS-TBNAwas found to be 96.5%; whereas, specificity and positive predictive values were 100%. The negative predictive value was calculated at 50%. Diagnostic accuracy of the procedure was found to be 96.67%.


CONCLUSIONS
EBUS-TBNA is a sensitive and a specific test and is accurate in diagnosing mediastinal and hilar pathologies.
Department of Histopathology, Army Medical College, Rawalpindi.
Mehreen
M
Fatima
Department of Pulmonology, Army Medical College, Rawalpindi.
Muhammad Aslam
MA
Khan
Department of Histopathology, Army Medical College, Rawalpindi.
Shahid
S
Jamal
Department of Pulmonology, Army Medical College, Rawalpindi.
Jawad Khaliq
JK
Ansari
Department of Pulmonology, Military Hospital, Rawalpindi.
Muhammad Usman
MU
Ullah
D000328:Adult; D044963:Biopsy, Fine-Needle / Q000379:methods*; D001980:Bronchi / Q000000981:diagnostic imaging*; D001999:Bronchoscopy / Q000379:methods*; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008482:Mediastinum / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D018084:Ultrasonography, Interventional