Intrauterine hematomas in the second and third trimesters associated with adverse pregnancy outcomes: a retrospective study.
OBJECTIVE
To carry out a retrospective study of the clinical features of patients with intrauterine hematoma in the second and third trimesters, and discuss the risk factors for poor pregnancy outcomes.


METHODS
A total of 398 patients who underwent routine examination in our hospital from January 2011 to December 2015 were classified into normal pregnancy (NP) group (N = 265) and adverse pregnancy (AP) group (N = 133), according to their pregnancy outcomes. Maternal clinical demographics, gestational age, location of hematoma, volume of hematoma, and accompanying contraction and vaginal bleeding were recorded.


RESULTS
The average age of pregnant women in the NP and AP groups was 28.25 ± 4.06 and 29.5 ± 5.06 years, respectively (p = 0.007). Gestational age at first detection of hematoma was 15.11 ± 5.13 weeks in the NP group compared with 21.22 ± 8.25 weeks in the AP group (p < 0.001). In the AP group, the incidence of retroplacental hematoma (54.1%) and palpable contractions (62.8%) was significantly higher than in the NP group (25.7% and 12.1%, respectively; p < 0.01). However, similar maternal parity or history of delivery, volume of hematoma and incidence of vaginal bleeding were found.


CONCLUSIONS
Intrauterine hematoma in the second and third trimesters is a sign of pathological pregnancy, resulting in adverse outcomes. Maternal age, gestational age at first diagnosis, location of hematoma and accompanying contraction are risk factors for poor pregnancy outcomes.
a Department of Obstetrics , Guangzhou Women and Children's Medical Center, Guangzhou Medical University , Guangzhou , China.
Wanqing
W
Ji
a Department of Obstetrics , Guangzhou Women and Children's Medical Center, Guangzhou Medical University , Guangzhou , China.
Weidong
W
Li
a Department of Obstetrics , Guangzhou Women and Children's Medical Center, Guangzhou Medical University , Guangzhou , China.
Shanshan
S
Mei
a Department of Obstetrics , Guangzhou Women and Children's Medical Center, Guangzhou Medical University , Guangzhou , China.
Ping
P
He
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006406:Hematoma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000473:pathology; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012189:Retrospective Studies; D012307:Risk Factors; D014463:Ultrasonography; D014592:Uterine Hemorrhage / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*
Intrauterine hematoma; pregnancy complications; second and third trimester