Treatment of psoriasis with etanercept in immunocompromised patients: Two case reports.
Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF-α agent, without notable side-effects.
Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy clara.desimone@rm.unicatt.it.
Clara
C
De Simone
Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy.
Francesca
F
Perino
Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy.
Giacomo
G
Caldarola
Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy.
Magda
M
D'Agostino
Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy.
Ketty
K
Peris
Antitumour necrosis factor-α agents; comorbidities; etanercept; psoriasis; psoriatic arthritis
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