Investigational histone deacetylase inhibitors for treating pancreatic adenocarcinoma.
a Department of Internal Medicine I , Laboratory for Gastrointestinal Signal Transduction, UKSH Campus Kiel , Kiel , Germany.
Alexander
A
Arlt
b Institute for Experimental Cancer Research , Laboratory of Molecular Gastroenterology, - Christian-Albrechts-University & UKSH Campus Kiel , Kiel , Germany.
Heiner
H
Schäfer
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000201:enzymology / Q000473:pathology; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D015195:Drug Design; D015507:Drugs, Investigational / Q000494:pharmacology / Q000627:therapeutic use; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000201:enzymology / Q000473:pathology
D000970:Antineoplastic Agents; D015507:Drugs, Investigational; D056572:Histone Deacetylase Inhibitors
Drug resistance; epigenetic modulation; histone acetylation; pancreatic adenocarcinoma