Management Scheme for Cerebral Wegener Granulomatosis: An Unusual Pseudotumoral Skull Base Pathology.
Granulomatosis with polyangiitis (Wegener disease) is a rare antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis that seldom involves brain and meninges. We present a case of a 35-year-old woman with granulomatosis with polyangiitis involving the brain and the meninges. The histologic diagnosis required a complete resection of the lesion. Despite the possibility of postoperative wound infection, surgery was mandatory to ascertain the diagnostic and to treat locally.
Department of Neurosurgery, Lariboisière Hospital, Paris, France; Paris-Diderot, Paris-Cité-Sorbone University, Paris, France. Electronic address: annelaure.bernat@aphp.fr.
Anne Laure
AL
Bernat
Department of Neurosurgery, Lariboisière Hospital, Paris, France; Paris-Diderot, Paris-Cité-Sorbone University, Paris, France.
Etienne
E
Lefevre
Paris-Diderot, Paris-Cité-Sorbone University, Paris, France; Department of Internal Medicine, Lariboisière Hospital, Paris, France.
Damien
D
Sène
Paris-Diderot, Paris-Cité-Sorbone University, Paris, France; Department of ENT, Lariboisière Hospital, Paris, France.
Philippe
P
Herman
Paris-Diderot, Paris-Cité-Sorbone University, Paris, France; Department of Pathology, Lariboisière Hospital, Paris, France.
Homa Adle
HA
Biassette
Department of Neurosurgery, Lariboisière Hospital, Paris, France; Paris-Diderot, Paris-Cité-Sorbone University, Paris, France.
Sébastien
S
Froelich
D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D001927:Brain Diseases / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D003399:Craniotomy; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006104:Granuloma, Plasma Cell / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D019291:Skull Base / Q000601:surgery*; D014057:Tomography, X-Ray Computed
D019268:Antibodies, Antineutrophil Cytoplasmic
Granuloma; Neurosurgical resection; cerebral granulomatosis