Protein-Based Hydrogels for Tissue Engineering.
The tunable mechanical and structural properties of protein-based hydrogels make them excellent scaffolds for tissue engineering and repair. Moreover, using protein-based components provides the option to insert sequences associated with promoting both cellular adhesion to the substrate and overall cell growth. Protein-based hydrogel components are appealing for their structural designability, specific biological functionality, and stimuli-responsiveness. Here we present highlights in the field of protein-based hydrogels for tissue engineering applications including design requirements, components, and gel types.
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.
Ashley C
AC
Schloss
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.
Danielle M
DM
Williams
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA. lynne.regan@yale.edu.|Department of Chemistry, Yale University, New Haven, CT, 06520, USA. lynne.regan@yale.edu.|Integrated Graduate Program in Physical and Engineering Biology, Yale University, New Haven, CT, 06520, USA. lynne.regan@yale.edu.
Lynne J
LJ
Regan
D020100:Hydrogels / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry*
D020100:Hydrogels; D011506:Proteins
Biocompatibility; Hydrogels; Mechanical properties; Protein engineering; Protein materials; Self-assembly; Smart biomaterials; Stimuli-responsive materials; Tissue engineering
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