New devices and techniques for endoscopic closure of gastrointestinal perforations.
Gastrointestinal perforations, which need to be managed quickly, are associated with high morbidity and mortality. Treatments used to close these perforations range from surgery to endoscopic therapy. Nowadays, with the development of new devices and techniques, endoscopic therapy is becoming more popular. However, there are different indications and clinical efficacies between different methods, because of the diverse properties of endoscopic devices and techniques. Successful management also depends on other factors, such as the precise location of the perforation, its size and the length of time between the occurrence and diagnosis. In this study, we performed a comprehensive review of various devices and introduced the different techniques that are considered effective to treat gastrointestinal perforations. In addition, we focused on the different methods used to achieve successful closure, based on the literature and our clinical experiences.
Yue Li, Jian-Hua Wu, Yan Meng, Qiang Zhang, Wei Gong, Si-De Liu, Department of Gastroenterology, Guangdong Provincial Key Laboratory of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Yue
Y
Li
Yue Li, Jian-Hua Wu, Yan Meng, Qiang Zhang, Wei Gong, Si-De Liu, Department of Gastroenterology, Guangdong Provincial Key Laboratory of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Jian-Hua
JH
Wu
Yue Li, Jian-Hua Wu, Yan Meng, Qiang Zhang, Wei Gong, Si-De Liu, Department of Gastroenterology, Guangdong Provincial Key Laboratory of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Yan
Y
Meng
Yue Li, Jian-Hua Wu, Yan Meng, Qiang Zhang, Wei Gong, Si-De Liu, Department of Gastroenterology, Guangdong Provincial Key Laboratory of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Qiang
Q
Zhang
Yue Li, Jian-Hua Wu, Yan Meng, Qiang Zhang, Wei Gong, Si-De Liu, Department of Gastroenterology, Guangdong Provincial Key Laboratory of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Wei
W
Gong
Yue Li, Jian-Hua Wu, Yan Meng, Qiang Zhang, Wei Gong, Si-De Liu, Department of Gastroenterology, Guangdong Provincial Key Laboratory of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Si-De
SD
Liu
D000007:Abdominal Injuries / Q000209:etiology / Q000601:surgery*; D003106:Colon / Q000601:surgery; D004386:Duodenum / Q000601:surgery; D019723:Endoscopes; D016099:Endoscopy, Gastrointestinal / Q000295:instrumentation* / Q000379:methods*; D004939:Esophageal Perforation / Q000209:etiology / Q000601:surgery*; D004947:Esophagus / Q000601:surgery; D005340:Fibrinogen / Q000737:chemistry; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery*; D008670:Metals / Q000737:chemistry; D010969:Plastics; D015607:Stents; D013525:Surgical Instruments; D013917:Thrombin / Q000737:chemistry; D016896:Treatment Outcome
D008670:Metals; D010969:Plastics; D005340:Fibrinogen; D013917:Thrombin
Devices; Endoscopic closure; Gastrointestinal perforations; Techniques; Treatment
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