The Functional and Structural Neuroanatomy of Systems Consolidation for Autobiographical and Semantic Memory.
It is well established that patients with memory impairment have more difficulty retrieving memories from the recent past relative to the remote past and that damage to the medial temporal lobe (MTL) plays a key role in this pattern of impairment. The precise role of the MTL and how it may interact with other brain regions remains an area of active research. We investigated the role of structures in a memory network that supports remembering. Our chapter focuses on two types of memory: episodic memory and semantic memory. Findings from studies of patients with brain damage and neuroimaging studies in patients and healthy individuals were considered together to identify the functional and structural neuroanatomy of past remembrance.
Department of Psychology, University of California San Diego, San Diego, CA, 92093, USA.|Veteran Affairs San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA, 92161, USA.
Adam J O
AJO
Dede
Department of Psychiatry, University of California San Diego, San Diego, CA, 92093, USA. cnsmith@ucsd.edu.|Veteran Affairs San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA, 92161, USA. cnsmith@ucsd.edu.
Christine N
CN
Smith
D000818:Animals; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000502:physiology*; D061212:Memory, Episodic
Autobiographical memory; Connectivity; Lesion; Neuroimaging; Patient; Retrograde amnesia; Semantic memory