Functional connectivity patterns of normal human swallowing: difference among various viscosity swallows in normal and chin-tuck head positions.
Consuming thicker fluids and swallowing in the chin-tuck position has been shown to be advantageous for some patients with neurogenic dysphagia who aspirate due to various causes. The anatomical changes caused by these therapeutic techniques are well known, but it is unclear whether these changes alter the cerebral processing of swallow-related sensorimotor activity. We sought to investigate the effect of increased fluid viscosity and chin-down posture during swallowing on brain networks. 55 healthy adults performed water, nectar-thick, and honey thick liquid swallows in the neutral and chin-tuck positions while EEG signals were recorded. After pre-processing of the EEG timeseries, the time-frequency based synchrony measure was used for forming the brain networks to investigate whether there were differences among the brain networks between the swallowing of different fluid viscosities and swallowing in different head positions. We also investigated whether swallowing under various conditions exhibit small-world properties. Results showed that fluid viscosity affects the brain network in the Delta, Theta, Alpha, Beta, and Gamma frequency bands and that swallowing in the chin-tuck head position affects brain networks in the Alpha, Beta, and Gamma frequency bands. In addition, we showed that swallowing in all tested conditions exhibited small-world properties. Therefore, fluid viscosity and head positions should be considered in future swallowing EEG investigations.
Department of Electrical and Computer Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: ivj2@pitt.edu.
Iva
I
Jestrović
Department of Communication Science and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA, USA; Department of Otolaryngology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: jcoyle@pitt.edu.
James L
JL
Coyle
Department of Medicine, Division of Geratric Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: ksp9@pitt.edu.
Subashan
S
Perera
Department of Electrical and Computer Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: esejdic@ieee.org.
Ervin
E
Sejdić
D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000502:physiology*; D002680:Chin / Q000502:physiology; D003679:Deglutition / Q000502:physiology*; D060766:Drinking Water; D004569:Electroencephalography; D005260:Female; D000067030:Fruit and Vegetable Juices; D006801:Humans; D008297:Male; D008875:Middle Aged; D009434:Neural Pathways / Q000502:physiology; D011187:Posture / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D014783:Viscosity; D055815:Young Adult
D060766:Drinking Water
Brain networks; Dysphagia; EEG; Fluid viscosity; Swallowing
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