Limb-salvage treatment of en-block resected distal femoral tumors with endoprosthesis of all-polyethylene tibial component: a 9-year follow-up study.
OBJECTIVE
To evaluate the medium-term outcome of limb-salvage surgery using all-polyethylene tibial endoprosthetic replacement following en-block resection for distal femoral tumors.


METHODS
Forty-nine patients with distal femoral tumor were treated between June 2006 and June 2012. The follow-up period was 6-110 months (average 53.4 months). The prosthetic survival was analyzed using the Kaplan-Meier method. The classification of failure of limb salvage after reconstructive surgery for bone tumors was adapted. Limb function was evaluated with the scoring system of the Musculoskeletal Tumor Society (MSTS).


RESULTS
Complications were observed in six cases (12.2%). Four suffered infection around the prosthesis, of which two cases were treated with debridement, drainage, and antibiotics without removal of the prosthesis, and the other two cases underwent amputation. Two cases were identified as radiographically loose at 7 year follow-up and did not require revision surgery. One patient underwent amputation due to local recurrence. Failure of limb salvage occurred in nine cases (18.4%), of which two cases were of type 1A, two cases of type 2B, three cases of type 4A, one case of type 4B, and one case of type 5A. The mean MSTS score was 84.3%. Twelve cases died due to distant metastases (24.5%), and the average survival time for these patients was 13.5 months. Thirty-seven patients survived (75.5%), for whom the average follow-up time was 66.3 months and the 5-year prosthetic survival rate was 88.2%.


CONCLUSIONS
The outcome of medium-term and long-term clinical follow-up was satisfactory. All-polyethylene tibial endoprosthetic replacement following en-block resection can be an alternative method of limb salvage for distal femoral tumors.
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Fan
F
Tang
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Yong
Y
Zhou
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Li
L
Min
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Wenli
W
Zhang
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Rui
R
Shi
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Yi
Y
Luo
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Hong
H
Duan
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Chongqi
C
Tu
all-polyethylene tibia; distal femur; endoprosthetic replacement; limb salvage; tumor
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