Clinical and Laboratory Profile of Dengue Fever.
OBJECTIVE
Dengue fever is one of the most common arboviral mediated outbreaks reported with increased prevalence year after year with considerable morbidity and mortality. This study was designed to assess the clinical and biochemical parameters of dengue fever patients.


METHODS
Prospective observational study was undertaken among adult patients in a military hospital. Five hundred fiteen patients were studied and analysed. All patients who were NS1 antigen/IgM dengue positive were included in the study. Clinical features, hematological and biochemical parameters were noted.


RESULTS
Of the 515 patients studied, majority were males (72.81%). Fever was the major symptom (100%) followed by headache (94.75%), myalgia (90.67%), retroorbital pain (18.25%), conjunctival injection (39.41%), rash (37.86%), abdominal pain (24.46%), pleural effusion (20%) and ascites (16.31%). Significant derangements in platelet (69.51%), leucocyte counts (20.19%) and serum transaminases (88.54%) were noted. Mortality rate was 0.77%.


CONCLUSIONS
Fever associated with headache, retroorbital pain, erythematous morbilliform rash, conjunctival suffusion and itching in palms and soles along with thrombocytopenia, leucopenia, elevated liver transaminases should prompt a clinician on the possibility of dengue infection. Platelet transfusions have little role in management of dengue patients.
Department of Medicine, Military Hospital, Agra, Uttar Pradesh.
Rajesh
R
Deshwal
Department of Medicine, Military Hospital, Agra, Uttar Pradesh.
Md Ishaque
MI
Qureshi
Department of Medicine, Military Hospital, Agra, Uttar Pradesh.
Raj
R
Singh
D015746:Abdominal Pain / Q000209:etiology / Q000503:physiopathology; D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001201:Ascites / Q000209:etiology / Q000503:physiopathology; D001219:Aspartate Aminotransferases / Q000097:blood; D002648:Child; D003229:Conjunctival Diseases / Q000209:etiology / Q000503:physiopathology; D003715:Dengue / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D005076:Exanthema / Q000209:etiology / Q000503:physiopathology; D005260:Female; D005334:Fever / Q000209:etiology / Q000503:physiopathology; D006261:Headache / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D007970:Leukopenia / Q000097:blood / Q000209:etiology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D063806:Myalgia / Q000209:etiology / Q000503:physiopathology; D010996:Pleural Effusion / Q000209:etiology / Q000503:physiopathology; D011446:Prospective Studies; D013921:Thrombocytopenia / Q000097:blood / Q000209:etiology; D055815:Young Adult
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase