Evaluation of Prostate Cancer with 11C-Choline PET/CT for Treatment Planning, Response Assessment, and Prognosis.
The aim of this review is to report on the value of11C-choline PET imaging as a diagnostic procedure for metastasis-directed therapies. Furthermore, the role of11C-choline PET/CT as a diagnostic tool for monitoring castration-resistant prostate cancer patients treated with systematic therapy is assessed. Finally, the role of11C-choline PET/CT in the prediction of survival in both castration-resistant prostate cancer patients and hormone-naïve patients is investigated.
Service of Nuclear Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; and.
Francesco
F
Ceci
Service of Nuclear Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; and paolo.castellucci@aosp.bo.it.
Paolo
P
Castellucci
Service of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Paola
P
Mapelli
Service of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Elena
E
Incerti
Service of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Maria
M
Picchio
Service of Nuclear Medicine, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; and.
Stefano
S
Fanti
D002794:Choline / Q000031:analogs & derivatives*; D019317:Evidence-Based Medicine; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000473:pathology / Q000517:prevention & control*; D009367:Neoplasm Staging; D017063:Outcome Assessment, Health Care / Q000379:methods; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy*; D019275:Radiopharmaceuticals
D019275:Radiopharmaceuticals; C447081:methyl carbon-11 choline; D002794:Choline
11C-choline PET/CT; PET-guided therapies; metastasis-directed therapies; salvage lymph node dissection; salvage radiotherapy