Unusual atypical language lateralization.
Determining the language-dominant hemisphere is essential for planning epilepsy surgery. A 60-year-old right-handed woman with epilepsy since age 16 failed a partial right anterior lobectomy at age 21. Later, a brain MRI found extensive right-sided cortical dysplasia and periventricular heterotopia. Subsequently, prolonged video-EEG monitoring localized her seizures to the right temporoparietal region. Functional MRI was inconclusive in lateralizing her language, prompting a Wada test, which strongly lateralized language to the right. This unique case of atypical language representation in a right-handed individual with an extensive right-hemispheric congenital malformation and seizure focus illustrates the important thorough presurgical language assessment.
West Virginia University, Department of Neurology, 1 Medical Center Drive, Morgantown, WV 26506, United States.
Muhammad T
MT
Khan
West Virginia University, Department of Neurology, 1 Medical Center Drive, Morgantown, WV 26506, United States.
Roger
R
Oghlakian
West Virginia University, Department of Neurology, 1 Medical Center Drive, Morgantown, WV 26506, United States.
Mohamad Z
MZ
Koubeissi
Epileptic Disord. 2007 Jun;9(2):111-26
17525019
Epilepsia. 2009 Jun;50(6):1505-16
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