A Rare Case of S310F Somatic ERBB2 Mutation in a HER2-Nonamplified Breast Cancer.
Department of Medicine, University at Buffalo, Buffalo, NY.
Sakshi
S
Jasra
Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY.
Mateusz
M
Opyrchal
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Larry
L
Norton
Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY. Electronic address: Rutika.Mehta@RoswellPark.org.
Rutika
R
Mehta
D000368:Aged; D000818:Animals; D000074322:Antineoplastic Agents, Immunological / Q000494:pharmacology / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics* / Q000556:secondary / Q000628:therapy; D001940:Breast / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000235:genetics* / Q000556:secondary / Q000628:therapy; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D017024:Chemotherapy, Adjuvant / Q000379:methods; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D005260:Female; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics* / Q000556:secondary / Q000628:therapy; D008327:Mammography; D015412:Mastectomy, Segmental; D009154:Mutation; D000072078:Positron Emission Tomography Computed Tomography; D018714:Radiotherapy, Adjuvant; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000235:genetics*; D021701:Sentinel Lymph Node Biopsy; D000068878:Trastuzumab / Q000494:pharmacology / Q000627:therapeutic use*; D016896:Treatment Outcome
D000074322:Antineoplastic Agents, Immunological; D018719:Erb-b2 Receptor Tyrosine Kinases; D000068878:Trastuzumab; C508053:ERBB2 protein, human
Immunohistochemistry; Neratinib; Personalized medicine; Pertuzumab; Trastuzumab