Transport of sulfacetamide and levofloxacin in granular porous media under various conditions: Experimental observations and model simulations.
Understanding the fate and transport of antibiotics in porous media can help reduce their contamination risks to soil and groundwater systems. In this work, batch and column experiments were conducted to determine the interactions between two representative antibiotics, sulfacetamide (SA) and levofloxacin (LEV), and sand porous media under various solution pH, humic acid (HA) concentration, grain size, and moisture content conditions. Batch sorption experimental results indicated that the sand had relatively strong bonding affinity to LEV, but little sorption of SA under different pH, HA concentration, grain size conditions. Results from the packed sand column experiments showed that SA had extremely high mobility in the porous media for all combinations of pH, HA concentration, grain size, and moisture content. The mass recovery of SA was higher than 98.5% in all the columns with the exception of the one packed with fine sand (97.2%). The retention of LEV in the columns was much higher and the recovery rates ranged from 0% to 71.1%. Decreases in solution pH, HA concentration, grain size, or moisture content reduced the mobility of LEV in the columns under the tested conditions. These results indicated that type of antibiotics and environmental conditions also played an important role in controlling their fate and transport in porous media. Mathematical models were applied to simulate and interpret experimental data, and model simulations described the interactions between the two antibiotics and sand porous media very well. Findings from this study elucidated the key factors and processes controlling the fate of SA and LEV in porous media, which can inform the prediction and assessment of the environmental risks of antibiotics.
Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Hydrosciences Department, Nanjing University, Nanjing 210023, China.
Shunan
S
Dong
Department of Agricultural and Biological Engineering, University of Florida, Gainesville, FL 32611, USA.
Bin
B
Gao
Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Hydrosciences Department, Nanjing University, Nanjing 210023, China. Electronic address: sunyy@nju.edu.cn.
Yuanyuan
Y
Sun
Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Hydrosciences Department, Nanjing University, Nanjing 210023, China.
Xiaoqing
X
Shi
Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Hydrosciences Department, Nanjing University, Nanjing 210023, China.
Hongxia
H
Xu
Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Hydrosciences Department, Nanjing University, Nanjing 210023, China.
Jianfeng
J
Wu
Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Hydrosciences Department, Nanjing University, Nanjing 210023, China. Electronic address: jcwu@nju.edu.cn.
Jichun
J
Wu
D000891:Anti-Infective Agents, Local; D000892:Anti-Infective Agents, Urinary; D004784:Environmental Monitoring; D060587:Groundwater / Q000737:chemistry; D064704:Levofloxacin / Q000032:analysis*; D008962:Models, Theoretical; D016062:Porosity; D012987:Soil / Q000737:chemistry; D012989:Soil Pollutants / Q000032:analysis*; D013409:Sulfacetamide / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D000891:Anti-Infective Agents, Local; D000892:Anti-Infective Agents, Urinary; D012987:Soil; D012989:Soil Pollutants; D014874:Water Pollutants, Chemical; D013409:Sulfacetamide; D064704:Levofloxacin
Antibiotics; Chemical of emerging concerns; Mobilization; Porous media; Retention