A new C20-diterpenoid alkaloid from the lateral roots of Aconitum carmichaeli.
A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhibitory concentration of 8 μg/mL.
a School of Chemical Science and Technology , Yunnan University , Kunming , P.R. China.
Jing
J
Yu
a School of Chemical Science and Technology , Yunnan University , Kunming , P.R. China.
Tian-Peng
TP
Yin
a School of Chemical Science and Technology , Yunnan University , Kunming , P.R. China.
Jia-Peng
JP
Wang
a School of Chemical Science and Technology , Yunnan University , Kunming , P.R. China.
Rui-Feng
RF
Mei
a School of Chemical Science and Technology , Yunnan University , Kunming , P.R. China.
Le
L
Cai
a School of Chemical Science and Technology , Yunnan University , Kunming , P.R. China.
Zhong-Tao
ZT
Ding
D031841:Aconitum / Q000737:chemistry*; D000470:Alkaloids / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification; D001412:Bacillus subtilis / Q000187:drug effects; D004224:Diterpenes / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D013057:Spectrum Analysis
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D004224:Diterpenes
Aconitum carmichaeli; Ranunculaceae; antibacterial; carmichaedine; diterpenoid alkaloid