Visible-Light-Induced Cascade Reaction of Isocyanides and N-Arylacrylamides with Diphenylphosphine Oxide via Radical C-P and C-C Bond Formation.
An effective photoredox-mediated tandem phosphorylation/cyclization reaction of diphenylphosphine oxide with three types of radical acceptors leads to P(O)Ph2-containing phenanthridines, isoquinolines, and indolin-2-ones by formation of both C-P and C-C bonds. [Ir(ppy)2(dtbpy)]PF6(1 mol %) was used as the catalyst, CsF or Cs2CO3as the base, and K2S2O8as the oxidant. A series of functional groups can be tolerated at room temperature. Moderate to good yields were generated.
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, Jiangsu 210023, China.
Chun-Xiao
CX
Li
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, Jiangsu 210023, China.
De-Shuang
DS
Tu
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, Jiangsu 210023, China.
Rui
R
Yao
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, Jiangsu 210023, China.
Hong
H
Yan
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing, Jiangsu 210023, China.
Chang-Sheng
CS
Lu