First description of herpes simplex virus type 1 epididymo-orchitis: A new clinical form of herpes simplex virus infection during septic shock?
Genital herpes is increasingly caused by herpes simplex virus type 1 (HSV-1), but recurrences are less frequent than with HSV-2. Distinguishing between primary genital infection and reactivation can be difficult, but HSV-1 more often causes severe primary infections and fewer recurrences. However, as virus reactivation is common during septic shock, a severe form of HSV-1 reactivation can occur in locations other than the lungs, which remain the most common site. The case of a 79-year-old Caucasian man who presented with HSV-1 epididymo-orchitis after three episodes of severe sepsis or septic shock in the context of acute biliary necrotizing pancreatitis is described. This is the first reported case of HSV-1 epididymo-orchitis due to virus reactivation during sepsis.
Department of Anesthesia and Intensive Care, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Dr Mélanie
DM
Fromentin
Department of Infectious Diseases, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Remy
R
Gauzit
Department of Anesthesia and Intensive Care, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Benoit
B
Gille
Department of Anesthesia and Intensive Care, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Charles Marc
CM
Samama
CT, computed tomography; ELISA, enzyme linked immunosorbent assay; Epididymo-orchitis; Health care-associated infection; Herpesviridae; ICU, intensive care unit; Immunosuppression; Necrotizing pancreatitis; PCR, polymerase chain reaction; SOFA, sepsis-related organ failure assessment score; Septic shock; WOPN, walled-off pancreatic necrosis
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