Clinical Effects of Krachaidum ( Kaempferia parviflora): A Systematic Review.
Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included. Even though results found that Krachaidum significantly increased hand grip strength and enhanced sexual erotic stimuli, these were based on only 2 studies and 1 study, respectively. With regard to harmful effects, we found no adverse events reported even when Krachaidum 1.35 g/day was used. Therefore, future studies of Krachaidum are needed with regards to both safety and efficacy outcomes.
1 University of Phayao, Phayao, Thailand.|2 Monash University Malaysia, Kuala Lumpur, Malaysia.|3 Naresuan University, Phitsanulok, Thailand.
Surasak
S
Saokaew
1 University of Phayao, Phayao, Thailand.
Preyanate
P
Wilairat
1 University of Phayao, Phayao, Thailand.
Paranya
P
Raktanyakan
3 Naresuan University, Phitsanulok, Thailand.
Piyameth
P
Dilokthornsakul
3 Naresuan University, Phitsanulok, Thailand.
Teerapon
T
Dhippayom
3 Naresuan University, Phitsanulok, Thailand.
Chuenjid
C
Kongkaew
3 Naresuan University, Phitsanulok, Thailand.
Rosarin
R
Sruamsiri
4 Department for Development of Thai Traditional and Alternative Medicine, Ministry of Public Health, Nonthaburi, Thailand.
Anchalee
A
Chuthaputti
2 Monash University Malaysia, Kuala Lumpur, Malaysia.|3 Naresuan University, Phitsanulok, Thailand.|5 University of Queensland, Brisbane, Queensland, Australia.|6 University of Wisconsin-Madison, WI, USA.
Nathorn
N
Chaiyakunapruk
D002986:Clinical Trials as Topic; D004734:Energy Metabolism / Q000187:drug effects; D015444:Exercise; D018737:Hand Strength; D006801:Humans; D010410:Penile Erection / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D030521:Zingiberaceae
D010936:Plant Extracts
Kaempferia parviflora; complementary and alternative medicine; systematic review
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