Tethered capsule endomicroscopy: from bench to bedside at a primary care practice.
Due to the relatively high cost and inconvenience of upper endoscopic biopsy and the rising incidence of esophageal adenocarcinoma, there is currently a need for an improved method for screening for Barrett’s esophagus. Ideally, such a test would be applied in the primary care setting and patients referred to endoscopy if the result is suspicious for Barrett’s. Tethered capsule endomicroscopy (TCE) is a recently developed technology that rapidly acquires microscopic images of the entire esophagus in unsedated subjects. Here, we present our first experience with clinical translation and feasibility of TCE in a primary care practice. The acceptance of the TCE device by the primary care clinical staff and patients shows the potential of this device to be useful as a screening tool for a broader population.
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United StatesbHarvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, United StatescStrasbourg University, CNRS, ICube Laboratory, 1 Place de l'Hopital, Strasbourg 67091, France.
Michalina J
MJ
Gora
Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, United StatesdMassachusetts General Hospital, Division of General Internal Medicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Leigh H
LH
Simmons
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United StateseInstitut des Maladies de l'Appareil Digestif, CHU Nantes, Hôtel Dieu, place Alexis Ricordeau, Nantes 44000, France.
Lucille
L
Quénéhervé
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Catriona N
CN
Grant
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Robert W
RW
Carruth
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Weina
W
Lu
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Aubrey
A
Tiernan
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United StatesbHarvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, United States.
Jing
J
Dong
Massachusetts General Hospital, Division of General Internal Medicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Beth
B
Walker-Corkery
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Amna
A
Soomro
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United StatesbHarvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, United States.
Mireille
M
Rosenberg
Massachusetts General Hospital, Division of General Internal Medicine, 55 Fruit Street, Boston, Massachusetts 02114, United States.
Joshua P
JP
Metlay
Massachusetts General Hospital, Wellman Center for Photomedicine, 55 Fruit Street, Boston, Massachusetts 02114, United StatesbHarvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, United StatesfMassachusetts General Hospital, Department of Pathology, 55 Fruit Street, Boston, Massachusetts 02114, United StatesgHarvard-MIT Division of Health Sciences Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Guillermo J
GJ
Tearney
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