Biospecimen Sharing Among Hispanic Women in a Safety-Net Clinic: Implications for the Precision Medicine Initiative.
Biospecimen donation is key to the Precision Medicine Initiative, which pioneers a model for accelerating biomedical research through individualized care. Personalized medicine should be made available to medically underserved populations, including the large and growing US Hispanic population. We present results of a study of 140 Hispanic women who underwent a breast biopsy at a safety-net hospital and were randomly assigned to receive information and request for consent for biospecimen and data sharing by the patient's physician or a research assistant. Consent rates were high (97.1% and 92.9% in the physician and research assistant arms, respectively) and not different between groups (relative risk [RR] = 1.05, 95% confidence interval [CI] = 0.96 to 1.10). Consistent with a small but growing literature, we show that perceptions of Hispanics' unwillingness to participate in biospecimen sharing for research are not supported by data. Safety-net clinics and hospitals offer untapped possibilities for enhancing participation of underserved populations in the exciting Precision Medicine Initiative.
Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.|Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA.
Jesse N
JN
Nodora
Department of Surgery, Maricopa Medical Center, Phoenix, AZ, USA.
Ian K
IK
Komenaka
Department of Surgery, Maricopa Medical Center, Phoenix, AZ, USA.
Marcia E
ME
Bouton
Department of Biomedical Informatics, University of California, San Diego, La Jolla, CA, USA.
Lucila
L
Ohno-Machado
Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Richard
R
Schwab
Department of Biomedical Informatics, University of California, San Diego, La Jolla, CA, USA.
Hyeon-Eui
HE
Kim
Department of Biomedical Informatics, University of California, San Diego, La Jolla, CA, USA.
Claudiu
C
Farcas
Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Giovanna
G
Perez
Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.|Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA.
Maria
M
Elena Martinez
D000328:Adult; D018070:Biological Specimen Banks; D001706:Biopsy; D001940:Breast / Q000473:pathology*; D003299:Cooperative Behavior; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D033181:Information Dissemination; D007258:Informed Consent; D008875:Middle Aged; D057285:Precision Medicine; D011897:Random Allocation; D064876:Safety-net Providers; D035862:Vulnerable Populations
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