Altered Resting-State Signals in Patients with Acute Stroke In or Under the Thalamus.
Previous studies have suggested that cortical functional reorganization is associated with motor recovery after stroke and that normal afferent sensory information is very important in that process. In this study, we selected patients who had a stroke in or under the thalamus, with potentially impaired afferent sensory information and analyzed the differences between these patients and healthy controls at three levels: brain regions, the functional connectivity between brain areas, and the whole-brain functional network. Compared with healthy controls, regional homogeneities in the left middle temporal gyrus decreased and functional connectivity between the left middle temporal gyrus and the stroke area increased in the patients. However, there was no significant change in the whole-brain functional network. By focusing on stroke located in or under the thalamus, our study contributes to wider inquiries into understanding and treating stroke.
Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, and School of Life Sciences, University of Science and Technology of China, Hefei, 230026, China.
Lijun
L
Chen
Department of Medical Iconography, Anhui University of Chinese Medicine, Hefei, 230031, China.
Chuanfu
C
Li
Department of Medical Iconography, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China. yjszhaij@126.com.
Jian
J
Zhai
Department of Medical Iconography, Anhui University of Chinese Medicine, Hefei, 230031, China.
Anqin
A
Wang
Department of Medical Iconography, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, China.
Qin
Q
Song
Department of Medical Iconography, Provincial Hospital Affiliated to Anhui Medical University, Hefei, 230001, China.
Ying
Y
Liu
Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, and School of Life Sciences, University of Science and Technology of China, Hefei, 230026, China.
Ru
R
Ma
Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, and School of Life Sciences, University of Science and Technology of China, Hefei, 230026, China.
Long
L
Han
School of Humanities and Social Science, University of Science and Technology of China, Hefei, 230026, China.
Yamikani
Y
Ndasauka
Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, and School of Life Sciences, University of Science and Technology of China, Hefei, 230026, China.
Xiaoming
X
Li
Center of Medical Physics and Technology, Hefei Science Center, Chinese Academy of Sciences, Hefei, 230031, China.
Hai
H
Li
Chinese Academy of Sciences Key Laboratory of Brain Function and Disease, and School of Life Sciences, University of Science and Technology of China, Hefei, 230026, China. zxcustc@ustc.edu.cn.|School of Humanities and Social Science, University of Science and Technology of China, Hefei, 230026, China. zxcustc@ustc.edu.cn.|Center of Medical Physics and Technology, Hefei Science Center, Chinese Academy of Sciences, Hefei, 230031, China. zxcustc@ustc.edu.cn.|Center for Biomedical Engineering, University of Science and Technology of China, Hefei, 230027, China. zxcustc@ustc.edu.cn.
Xiaochu
X
Zhang
D000368:Aged; D002545:Brain Ischemia / Q000150:complications; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D012146:Rest; D020521:Stroke / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D013788:Thalamus / Q000000981:diagnostic imaging*
D010100:Oxygen
ReHo; Resting-state; Stroke; Thalamus
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