Fully Regressive Melanoma: A Case Without Metastasis.
Fully regressive melanoma is a phenomenon in which the primary cutaneous melanoma becomes completely replaced by fibrotic components as a result of host immune response. Although 10 to 35 percent of cases of cutaneous melanomas may partially regress, fully regressive melanoma is very rare; only 47 cases have been reported in the literature to date. AH of the cases of fully regressive melanoma reported in the literature were diagnosed in conjunction with metastasis on a patient. The authors describe a case of fully regressive melanoma without any metastases at the time of its diagnosis. Characteristic findings on dermoscopy, as well as the absence of melanoma on final biopsy, confirmed the diagnosis.
Service de dermatologie, université catholique de Lille, hôpital Saint-Vincent-de-Paul, Lille, France;
Eric
E
Ehrsam
Department of Radiology, Northwestern University, Chicago, Illinois;
Joseph R
JR
Kallini
Service de dermatologie, université catholique de Lille, hôpital Saint-Vincent-de-Paul, Lille, France;
Damien
D
Lebas
Veterans Affairs Medical Center, Brooklyn, New York;
Amor
A
Khachemoune
Service de dermatologie, université catholique de Lille, hôpital Saint-Vincent-de-Paul, Lille, France;
Philippe
P
Modiano
Anatomopathologiste à Lille, Nordpathologie, Lille, France.
Hervé
H
Cotten
J Eur Acad Dermatol Venereol. 2008 Apr;22(4):514-5
18363926
J Interferon Cytokine Res. 1998 Jan;18(1):33-9
9475665
J Interferon Cytokine Res. 1999 Feb;19(2):171-7
10090402
Int J Cancer. 1997 Jul 17;72(2):241-7
9219827
Am J Clin Pathol. 2005 Jul;124(1):37-48
15923172
Br J Dermatol. 2005 May;152(5):1039-44
15888167
Arch Surg. 1997 May;132(5):553-6
9161401
J Natl Cancer Inst. 2001 Jul 18;93(14):1047-8
11459861
Ann Dermatol Venereol. 2007 Jun-Jul;134(6-7):521-5
17657177
Semin Surg Oncol. 1998 Jun;14(4):272-5
9588719
J Am Acad Dermatol. 2001 Oct;45(4):579-86
11568750
Br J Dermatol. 2008 Jun;158(6):1224-9
18341656
J Am Acad Dermatol. 2005 Jul;53(1):89-100
15965428
Histopathology. 1992 Apr;20(4):315-22
1577409