Optimisation of a Naviglio-assisted extraction followed by determination of piperine content in Piper longum extracts.
Studies were made to increase the yield of piperine extraction using Naviglio Extractor® solid-liquid dynamic extractor (SLDE) from fruits of Piper longum. The effects of ratio w/v were investigated and optimised for the best method. The maximum yield of piperine (317.7 mg/g) from P. longum fruits was obtained in SLDE 1:50 ethanol extract. Extraction yields of piperine obtained from Soxhlet extraction, decotion (International Organization for Standardization) and conventional maceration extraction methods were found to be 233.7, 231.8 and 143.6 mg/g, respectively. The results of the present study indicated that Naviglio Extractor® is an effective technique for the extraction of piperine from long pepper.
a Department of Pharmaceutical Sciences , University of Perugia , Perugia , Italy.
Giulia
G
Gigliarelli
a Department of Pharmaceutical Sciences , University of Perugia , Perugia , Italy.
Rita
R
Pagiotti
a Department of Pharmaceutical Sciences , University of Perugia , Perugia , Italy.
Diana
D
Persia
a Department of Pharmaceutical Sciences , University of Perugia , Perugia , Italy.
Maria Carla
MC
Marcotullio
D000470:Alkaloids / Q000032:analysis*; D052117:Benzodioxoles / Q000032:analysis*; D005638:Fruit / Q000737:chemistry; D031701:Piper / Q000737:chemistry*; D010880:Piperidines / Q000032:analysis*; D010936:Plant Extracts / Q000737:chemistry; D053284:Polyunsaturated Alkamides / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods*
D000470:Alkaloids; D052117:Benzodioxoles; D010880:Piperidines; D010936:Plant Extracts; D053284:Polyunsaturated Alkamides; C008922:piperine
Naviglio Extractor®; Piper longum; UV–VIS determination; extraction; piperine