Hepatitis E in Norway: seroprevalence in humans and swine.
In Norway, no published data on seroprevalence of hepatitis E virus (HEV) in humans and swine exists. Serum samples from blood donors, veterinarians, swine farm workers and swine were analysed by ELISA to estimate the seroprevalence of HEV in Norway and to investigate the association between direct contact with swine and HEV seroprevalence in humans. The seroprevalence of HEV IgG antibodies was 30% (24/79) in farm workers, 13% (21/163) in veterinarians, 14% (162/1200) in blood donors and 90% (137/153) in swine. Our results show a high seroprevalence of HEV in humans and swine in Norway. HEV seroprevalence in farm workers and blood donors increased with age, and veterinarians working with swine were twice as likely to be HEV seropositive compared to other veterinarians. High HEV seroprevalence in farm workers and veterinarians working with swine support previous reports suggesting swine as a reservoir for HEV infections in humans in Europe.
Norwegian Institute of Public Health,Department of Infectious Disease Epidemiology,Oslo,Norway.
H
H
Lange
Norwegian Institute of Public Health,Department of Virology,Oslo,Norway.
J
J
Øverbø
Norwegian Institute of Public Health,Department of Infectious Disease Epidemiology,Oslo,Norway.
K
K
Borgen
Norwegian Institute of Public Health,Department of Virology,Oslo,Norway.
S
S
Dudman
Norwegian Institute of Public Health,Department of Virology,Oslo,Norway.
G
G
Hoddevik
Norwegian Veterinary Institute,Oslo,Norway.
A M
AM
Urdahl
Norwegian Institute of Public Health,Department of Infectious Disease Epidemiology,Oslo,Norway.
L
L
Vold
Norwegian Veterinary Institute,Oslo,Norway.
S K
SK
Sjurseth
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006508:Hepatitis Antibodies / Q000097:blood; D016751:Hepatitis E / Q000453:epidemiology* / Q000662:veterinary*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D016273:Occupational Exposure; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology*; D055815:Young Adult
D006508:Hepatitis Antibodies; D007074:Immunoglobulin G
Estimating; hepatitis E; prevalence of disease; serology; zoonoses
Emerg Infect Dis. 2012 Aug;18(8):1358-60
22840183
BMC Res Notes. 2012 Apr 25;5:190
22534364
BMJ. 1990 Jun 9;300(6738):1475-6
2115383
J Clin Virol. 2013 Dec;58(4):624-8
24183927
BMC Vet Res. 2014 Jun 16;10:133
24934984
Emerg Infect Dis. 2011 Dec;17(12):2309-12
22172156
Vet Microbiol. 2013 Dec 27;167(3-4):394-402
24238666
J Clin Virol. 2013 Nov;58(3):504-8
24084601
Clin Infect Dis. 2008 Oct 15;47(8):1026-31
18781880
Int J Environ Res Public Health. 2013 Sep 25;10(10):4507-33
24071919
J Med Virol. 2010 May;82(5):799-805
20336757
Emerg Infect Dis. 2014 Nov;20(11):1914-7
25340881
Lancet. 2014 Nov 15;384(9956):1729-30
25078305
Curr Infect Dis Rep. 2014 Apr;16(4):399
24585215
Med Microbiol Immunol. 2012 May;201(2):239-44
21773797
Int J Food Microbiol. 2015 Jan 16;193:29-33
25462920
Food Environ Virol. 2015 Sep;7(3):213-23
26003323
Transfusion. 2014 Dec;54(12):3092-6
24889277
Vet Microbiol. 2010 Nov 20;146(1-2):144-9
20554125
J Clin Virol. 2013 Dec;58(4):629-34
24210958
Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9860-5
9275216
Curr Opin Virol. 2014 Feb;4:91-6
24513966
PLoS One. 2015 Mar 09;10(3):e0119576
25751574
Vet Res. 2010 Nov-Dec;41(6):46
20359452
Lancet. 2012 Jun 30;379(9835):2477-2488
22549046
Clin Microbiol Rev. 2014 Jan;27(1):116-38
24396139