A single session of exhaustive exercise markedly decreases circulating levels of guanidinoacetic acid in healthy men and women.
We evaluated the effects of exercise on circulating concentrations of guanidinoacetic acid (GAA) and creatine in 23 healthy volunteers subjected to running to exhaustion and free-weight bench-press to volitional failure. Blood was taken before and following each exercise session. Running induced a significant decrease in serum GAA by 20.1% (P < 0.001), while free-weight exercise reduced GAA by 11.7% (P < 0.001), suggesting the possible use of serum GAA as a novel biomarker of exhaustion.
a Applied Bioenergetics Lab, Biomedical Sciences Department, Faculty of Sport and Physical Education, University of Novi Sad, Lovcenska 16, Novi Sad 21000, Serbia.
Valdemar
V
Stajer
a Applied Bioenergetics Lab, Biomedical Sciences Department, Faculty of Sport and Physical Education, University of Novi Sad, Lovcenska 16, Novi Sad 21000, Serbia.
Tatjana
T
Trivic
a Applied Bioenergetics Lab, Biomedical Sciences Department, Faculty of Sport and Physical Education, University of Novi Sad, Lovcenska 16, Novi Sad 21000, Serbia.
Patrik
P
Drid
b Faculty of Sciences, University of Novi Sad, Novi Sad 21000, Serbia.
Milan
M
Vranes
a Applied Bioenergetics Lab, Biomedical Sciences Department, Faculty of Sport and Physical Education, University of Novi Sad, Lovcenska 16, Novi Sad 21000, Serbia.|c University of Belgrade School of Medicine, Belgrade, Belgrade 11000, Serbia.
Sergej M
SM
Ostojic
bench press; bioenergetics; bioénergétique; courir jusqu’à épuisement; creatine; creatinine; créatine; créatinine; développé au banc; running-to-exhaustion