title: Fine needle aspiration in intraocular metastasis from pleuropulmonary blastoma. A case report and a review of the literature.
abstract: Pleuropulmonary blastoma (PPB) is a rare primitive intrathoracic malignant neoplasm that occurs almost exclusively in children and adolescents. PPB is classified into three types according to the presence of cystic and solid areas. We report a case of PPB with an intraocular metastasis diagnosed by fine needle aspiration (FNA): 3-year-old female was treated for type II PPB by neoadjuvant chemotherapy and surgery. Four years later, she presented with an intraocular lesion. To differentiate between metastasis or other malignancy, a transcleral FNA was performed and showed two cellular populations represented by roundish malignant cells and spindle-shaped cells. The patient was treated with chemotherapy and diode laser ablation. A year later, the patient had enucleation and rare residual cells were found on the histological specimen. Patient remains disease-free 66 months after the last surgical treatment. Diagn. Cytopathol. 2017;45:156-160. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Pathology, Institut Curie, Paris, France.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Costa
authors.affiliation: Pathology, Institut Curie, Paris, France.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Klijanienko
authors.affiliation: Ophtalmology, Institut Curie, Paris, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Desjardins
authors.affiliation: Ophtalmology, Institut Curie, Paris, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Cassoux
authors.affiliation: Pathology, Hôpital Trousseau, Tours, France.
authors.forename: Marie Christine
authors.initials: MC
authors.lastname: Machet
authors.affiliation: Pediatrics, Institut Curie, Paris, France.
authors.forename: Helene
authors.initials: H
authors.lastname: Pacquement
mesh_terms: D044963:Biopsy, Fine-Needle; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000473:pathology* / Q000556:secondary; D005260:Female; D006801:Humans; D018202:Pulmonary Blastoma / Q000473:pathology*
keywords: fine needle aspiration; metastasis; pleuropulmonary blastoma; transcleral puncture