title: Soft-tissue amyloidoma with associated plasmacytoma.
abstract: Soft tissue amyloidoma with features similar to plasmacytoma, in absence of systemic amyloidosis, is an extremely rare finding. We hereby report the case of a 77 year old man who presented with a painless, nodular swelling on chest wall, diagnosed as soft tissue amyloidoma with plasma cell infiltration. Congo red staining was done to prove the presence of amyloid which showed characteristic "apple-green" birefringence on polarized microscopy. The plasma cells were monoclonal in origin as demonstrated by serum protein and immunofixation electrophoresis. To the best of our knowledge, this is the second such reported case. However close follow up is required, as this patient may develop multiple myeloma in future.
authors.affiliation: Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
authors.forename: Bibhas Saha
authors.initials: BS
authors.lastname: Dalal
authors.affiliation: Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
authors.forename: Piyabi
authors.initials: P
authors.lastname: Sarkar
authors.affiliation: Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
authors.forename: Namrata
authors.initials: N
authors.lastname: Maity
authors.affiliation: Nilam Diagnostic Centre, Kolkata, West Bengal, India.
authors.forename: Sayed Mahmood
authors.initials: SM
authors.lastname: Nadeem
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D001798:Blood Proteins / Q000032:analysis; D004586:Electrophoresis; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008853:Microscopy; D010954:Plasmacytoma / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D013909:Thorax / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D001798:Blood Proteins