title: Expedient Cobalt-Catalyzed C-H Alkynylation of (Enantiopure) Benzylamines.
abstract: A unified strategy for cobalt-catalyzed ortho-C-H bond alkynylation of benzylamines is reported. Simple, commercially available CoBr2was used as a cobalt source. The developed alkynylation strategy is robust and efficient and has a broad substrate scope including 1°, 2°, and 3° benzylamines. The mechanistic study shows that C-H bond cleavage is reversible, and the kinetic study illustrates that the rate of reaction depends solely on the catalyst.
authors.affiliation: Academy of Scientific and Innovative Research , New Delhi 110 025, India.
authors.forename: Vinod G
authors.initials: VG
authors.lastname: Landge
authors.affiliation: Academy of Scientific and Innovative Research , New Delhi 110 025, India.
authors.forename: Siba P
authors.initials: SP
authors.lastname: Midya
authors.affiliation: Academy of Scientific and Innovative Research , New Delhi 110 025, India.
authors.forename: Jagannath
authors.initials: J
authors.lastname: Rana
authors.forename: Dinesh R
authors.initials: DR
authors.lastname: Shinde
authors.affiliation: Academy of Scientific and Innovative Research , New Delhi 110 025, India.
authors.forename: Ekambaram
authors.initials: E
authors.lastname: Balaraman