title: Allergic contact dermatitis caused by the preservative 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one in black trousers.
authors.affiliation: Department of Dermatology, Osaka City University, Graduate School of Medicine, Osaka, 545-8585, Japan. o9oo3618749@med.osaka-cu.ac.jp.
authors.forename: Ayano
authors.initials: A
authors.lastname: Umekoji
authors.affiliation: Department of Dermatology, Osaka City University, Graduate School of Medicine, Osaka, 545-8585, Japan.
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Fukai
authors.affiliation: Department of Dermatology, Osaka City University, Graduate School of Medicine, Osaka, 545-8585, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Sowa-Osako
authors.affiliation: Department of Dermatology, Osaka City University, Graduate School of Medicine, Osaka, 545-8585, Japan.
authors.forename: Marina
authors.initials: M
authors.lastname: Manabe
authors.affiliation: Consumer Product Safety Technology Division, National Institute of Technology and Evaluation, Product Safety Technology Centre, Osaka, 559-0034, Japan.
authors.forename: Maki
authors.initials: M
authors.lastname: Kikugawa
authors.affiliation: Biosafety Analysis Division, National Institute of Technology and Evaluation, Biological Resource Centre, Tokyo, 151-0066, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Ishii
authors.affiliation: Biosafety Analysis Division, National Institute of Technology and Evaluation, Biological Resource Centre, Tokyo, 151-0066, Japan.
authors.forename: Kazumi
authors.initials: K
authors.lastname: Sasaki
authors.affiliation: Department of Dermatology, Osaka City University, Graduate School of Medicine, Osaka, 545-8585, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tsuruta
mesh_terms: D000328:Adult; D003020:Clothing / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D005260:Female; D006801:Humans; D007564:Japan; D007868:Leg Dermatoses / Q000209:etiology*; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D013844:Thiazoles / Q000009:adverse effects*
chemical_list: D011310:Preservatives, Pharmaceutical; D013844:Thiazoles; C080469:Kathon 930
keywords: 2-methyl-4-isothiazolin-3-one (MI); 2-octyl-isothiazol-3-one (OIT); 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT); 5-chloro-2-(2,4-dichlorophenoxyl)phenol (Triclosan); 5-chloro-2-methyl-4-isothiazolin-3-one (MCI); CAS no. 64359-81-5; case report; mixture 3:1 MCI/MI