title: Assignment of oxime and hydrazone configuration using1H-15N and13C-15N coupling measurements at natural abundance.
abstract: Measurement of1H-15N and13C-15N coupling constants at natural abundance is demonstrated to be a reliable and generic method to determine the configuration of oximes, hydrazines, and related systems. Data on1H-15N and13C-15N coupling constants on a variety of systems obtained at natural abundance confirm the geometric dependence of the measured1H-15N and13C-15N coupling constants. In addition, we summarize a simple "decision-tree" for determining configuration based on practical considerations of sample quantity, solubility, and complexity. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: DuPont Crop Protection, Stine Haskell Research Center, P.O. Box 30, Newark, DE, 19714, USA.
authors.forename: Mike
authors.initials: M
authors.lastname: Kline
authors.affiliation: DuPont Crop Protection, Stine Haskell Research Center, P.O. Box 30, Newark, DE, 19714, USA.
authors.forename: Dawn
authors.initials: D
authors.lastname: Pierce
authors.affiliation: DuPont Crop Protection, Stine Haskell Research Center, P.O. Box 30, Newark, DE, 19714, USA.
authors.forename: Steve
authors.initials: S
authors.lastname: Cheatham
keywords: 13C-15N coupling constant; 1H-15N coupling constant; HCNMBC; HSQMBC; configuration; oxime