title: Comparison of GreenLight laser and transurethral resection of the prostate baseline characteristics and outcomes: lessons learned from the Clinical Research Office of the Endourological Society GreenLight Laser Study.
abstract: BACKGROUND
  To compare baseline characteristics and outcomes of patients undergoing GreenLight laser vaporization (GL) or transurethral resection of the prostate (TURP) in a real life setting.
  
  
  METHODS
  In this prospective observational cohort, the Clinical Research Office of the Endourological Society (CROES) collected data of consecutive GL or TURP treated patients. Treatment involved one of three GL laser powers (80 W, 120 W or 180 W) based on availability in each participating centre, or TURP. Data on baseline characteristics as well as functional measures were collected at three time points: 6-12 weeks, 6, and 12months after surgery. Functional measures included urinary flow parameters, perceived prostate function (IPSS), perceived erectile function (IIEF-5) and complications.
  
  
  RESULTS
  Seven hundred thirteen patients underwent GL, and 234 patients underwent TURP. Overall, patients treated with GL show higher BMI, IIEF and medication use, together with lower urinary function (voided volume, incontinence, urinary retention) at baseline. After the procedure, despite higher antibiotic and antimuscarinic use and shorter hospital stay, readmission rates, PVR, PSA were higher, but Qmax, and IIEF were lower in the GL group. The rate of post-operative complications was 10.3% and 5.2% for the TURP and GL group, respectively (P=0.006).
  
  
  CONCLUSIONS
  We were unable to categorically state which procedure is superior. This observational study confirms that treatment decision for either TURP or GL is not based on patient characteristics.
authors.affiliation: Department of Urology, King's College Hospital, London, UK.
authors.forename: Gordon
authors.initials: G
authors.lastname: Muir
authors.affiliation: Department of Urology, Faculty and Teaching Hospital, Kralovske Vinohrady, Prague, Czech Republic.
authors.forename: Jiri
authors.initials: J
authors.lastname: Klecka
authors.affiliation: Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, OK, USA.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Culkin
authors.affiliation: Department of Urology, Center of Urology, Buenos Aires, Argentina.
authors.forename: Gabriel H
authors.initials: GH
authors.lastname: Barusso
authors.affiliation: Department of Urology, Isala Clinic, Zwolle, The Netherlands.
authors.forename: Jan
authors.initials: J
authors.lastname: Kums
authors.affiliation: Department of Urology, Asklepios Klinik St. Georg, Hamburg, Germany.
authors.forename: Claus
authors.initials: C
authors.lastname: Brunken
authors.affiliation: Department of Urology, Urology of Virginia, Eastern Virginia Medical School, Virginia Beach, VA, USA.
authors.forename: Gregg
authors.initials: G
authors.lastname: Eure
authors.affiliation: Department of Urology, Hospital General Royo Villanova, Zaragoza, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Rioja Sanz
authors.affiliation: Department of Urology, Advanced Urologic Surgery Institute, Madrid, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Gomez Sancha
authors.affiliation: Department of Urology, Private Lokman Hekim Hospitals, Etlik, Ankara, Turkey.
authors.forename: Muharrem M
authors.initials: MM
authors.lastname: Yildiz
authors.affiliation: Department of Urology, AMC University Hospital, Amsterdam, The Netherlands - J.J.delaRosette@amc.uva.nl.
authors.forename: Jean J
authors.initials: JJ
authors.lastname: de la Rosette
mesh_terms: D000368:Aged; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods*; D008297:Male; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000601:surgery*; D020728:Transurethral Resection of Prostate / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000209:etiology