title: The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China.
abstract: The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P[8] (85/107, 79.4 %), which showed high sequence similarity to G9P[8] strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections.
authors.affiliation: Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming, 650500, Yunnan, China.|Department of Clinical Laboratory, First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan, China.
authors.forename: Ziqin
authors.initials: Z
authors.lastname: Dian
authors.affiliation: Department of Clinical Laboratory, Kunming Children's Hospital, Kunming, 650034, Yunnan, China.
authors.forename: Mao
authors.initials: M
authors.lastname: Fan
authors.affiliation: Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming, 650500, Yunnan, China.
authors.forename: Binghui
authors.initials: B
authors.lastname: Wang
authors.affiliation: Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming, 650500, Yunnan, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Feng
authors.affiliation: Department of Information Center, First People's Hospital of Yunnan province, Kunming, 650032, Yunnan, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Ji
authors.affiliation: Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming, 650500, Yunnan, China.
authors.forename: Shuwei
authors.initials: S
authors.lastname: Dong
authors.affiliation: Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming, 650500, Yunnan, China.
authors.forename: A-Mei
authors.initials: AM
authors.lastname: Zhang
authors.affiliation: Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming, 650500, Yunnan, China.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Clinical Laboratory, First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Niu
authors.affiliation: Faculty of Environmental Science and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming, 650500, Yunnan, China. oliverxia2000@aliyun.com.
authors.forename: Xueshan
authors.identifier: http://orcid.org/0000-0003-1120-8870
authors.initials: X
authors.lastname: Xia
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D017720:Molecular Epidemiology; D015995:Prevalence; D012401:Rotavirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology
keywords: Children; Epidemiology; Gastroenteritis; Genotype; Rotavirus A