title: Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages.
abstract: The data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS-TOF/TOF. All newborns were separated into three gestational age groups, "Very Preterm" 29-32 weeks, "Moderate Preterm" 33-36 weeks, and, "Term" ≥37weeks. From each newborn, blood was drawn three times from birth to 1 month life. High-abundant serum proteins were depleted, and the minority ones were separated by 2DE and analyzed for significant expression differences. The data reflect analytic and clinic variables analyzed globally and categorized by gestational age in relation to IUGR and the optimization of conditions for 2-DE separation. The data from this study are related to the research article entitled "Alterations of Protein Expression in Serum of Infants with Intrauterine Growth Restriction and Different Gestational Ages" (M.D. Ruis-González, M.D. Cañete, J.L. Gómez-Chaparro, N. Abril, R. Cañete, J. López-Barea, 2015) [1]. The present dataset of serum IUGR newborn proteome can be used as a reference for any study involving intrauterine growth restriction during the first month of life.
authors.affiliation: Neonatology Unit, Pediatrics Service, Reina Sofía University Hospital, Andalusian Health Service, Menéndez Pidal Avenue, 14004 Córdoba, Spain.
authors.forename: M D
authors.initials: MD
authors.lastname: Ruiz-González
authors.affiliation: Maimonides Institute of Biomedical Research of Córdoba (IMIBIC), Menendez Pidal Avenue, 14004 Córdoba, Spain.
authors.forename: M D
authors.initials: MD
authors.lastname: Cañete
authors.affiliation: Experimental Unit Córdoba District, Andalusian Health Service, Isla Lanzarote s/n, 14011 Córdoba, Spain.
authors.forename: J L
authors.initials: JL
authors.lastname: Gómez-Chaparro
authors.affiliation: Epidemiology Unit Córdoba District, Andalusian Health Service, Isla Lanzarote s/n, 14011 Córdoba, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Torronteras
authors.affiliation: Department of Biochemistry and Molecular Biology, Severo Ochoa Building, Rabanales Campus, University of Córdoba, A4 highway, Km 396a, 14071 Córdoba, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Abril
authors.affiliation: Pediatric Endocrinology Section, Pediatrics Service, Reina Sofía University Hospital, Andalusian Health Service, Menéndez Pidal Avenue, 14004 Córdoba, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Cañete
authors.affiliation: Department of Biochemistry and Molecular Biology, Severo Ochoa Building, Rabanales Campus, University of Córdoba, A4 highway, Km 396a, 14071 Córdoba, Spain.
authors.forename: J L
authors.initials: JL
authors.lastname: López-Barea
keywords: Human newborn; Intrauterine growth restriction; Proteomics; Serum proteins; Venous blood