title: A new urticarial rash, diarrhoea and refractory hypotension in a man with a history of migraines.
abstract: We present the case of a man with a history of migraines treated with propanolol, referred with a rash, diarrhoea, vomiting and hypotension. Our case highlights how prior beta-blocker use may prolong anaphylaxis and cause refractory hypotension.
authors.affiliation: Royal Free London NHS Foundation Trust, London, UK drlucylamb@gmail.com.
authors.forename: Lucy
authors.initials: L
authors.lastname: Lamb
authors.affiliation: Institute of Immunity and Transplantation, University College London, London, UK.
authors.forename: David
authors.initials: D
authors.lastname: Lowe
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced / Q000150:complications; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007022:Hypotension / Q000175:diagnosis / Q000209:etiology; D008297:Male; D008881:Migraine Disorders / Q000150:complications / Q000188:drug therapy; D011433:Propranolol / Q000009:adverse effects / Q000627:therapeutic use; D053802:Tryptases / Q000097:blood; D014581:Urticaria / Q000175:diagnosis / Q000209:etiology
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol; D053802:Tryptases
keywords: Beta-blockers; prolonged anaphylaxis; refractory hypotension; tryptase