title: The ABCs of managing systolic heart failure: Past, present, and future.
abstract: Heart failure management is complex and constantly evolving. The American College of Cardiology and the American Heart Association (ACC/AHA) last issued evidence-based guidelines in 2013, and since then, new drugs and devices have been developed. This review presents an evidence-based approach to current heart failure management.
authors.affiliation: Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA. E-mail: isokwuosa@gmail.com.
authors.forename: Ike Stanley
authors.initials: IS
authors.lastname: Okwuosa
authors.affiliation: Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Oluseyi
authors.initials: O
authors.lastname: Princewill
authors.affiliation: Georgetown University School of Medicine, Washington, DC, USA.
authors.forename: Chiemeke
authors.initials: C
authors.lastname: Nwabueze
authors.affiliation: Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Lena
authors.initials: L
authors.lastname: Mathews
authors.affiliation: Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Steven
authors.initials: S
authors.lastname: Hsu
authors.affiliation: Director, Heart Failure Bridge Clinic, Advanced Heart Failure/Transplant Cardiology, Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.|Assistant Professor of Medicine, The Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Nisha A
authors.initials: NA
authors.lastname: Gilotra
authors.affiliation: Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Sabra
authors.initials: S
authors.lastname: Lewsey
authors.affiliation: Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Roger S
authors.initials: RS
authors.lastname: Blumenthal
authors.affiliation: Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: Stuart D
authors.initials: SD
authors.lastname: Russell
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000613:Aminobutyrates / Q000627:therapeutic use; D057911:Angiotensin Receptor Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001713:Biphenyl Compounds; D058409:Cardiac Resynchronization Therapy Devices; D017147:Defibrillators, Implantable; D004077:Digoxin / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D004338:Drug Combinations; D019317:Evidence-Based Medicine; D015444:Exercise; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices; D006801:Humans; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D017410:Practice Guidelines as Topic; D013599:Systole; D013777:Tetrazoles / Q000627:therapeutic use; D000068756:Valsartan
chemical_list: D000319:Adrenergic beta-Antagonists; D000613:Aminobutyrates; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D001713:Biphenyl Compounds; D004232:Diuretics; D004338:Drug Combinations; D000451:Mineralocorticoid Receptor Antagonists; D010446:Peptide Fragments; D013777:Tetrazoles; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain; D004077:Digoxin; D000068756:Valsartan; C549068:sacubitril and valsartan sodium hydrate drug combination