title: Blood pressure differences between office and home settings among Japanese normotensive subjects and hypertensive patients.
abstract: This study attempted to clarify the differences in blood pressure (BP) between the office (clinic) and home settings in patients with controlled, sustained, masked or white-coat hypertension. The following formula was used: office mean systolic BP (omSBP)-mean morning home SBP (mmhSBP)/office mean diastolic BP (omDBP)-mean morning home DBP (mmhDBP). The paired t-test was used for statistical analysis. The omSBP-mmhSBP/omDBP-mmhDBP calculation yielded the following results: among normotensive subjects, -1.1±11.2/-1.7±8.5 mm Hg (mean SBP and mean DBP were higher at home than in the office; n=451, P=0.038 in SBP, P=0.000 in DBP); in controlled hypertensive patients, -0.42±10.9/-2.2±8.2 mm Hg (n=1362, P=0.160 in SBP, P=0.000 in DBP); among sustained hypertensive patients, 5.6±14.7/0.048±9.9 mm Hg (n=1370, P=0.000 in SBP, P=0.857 in DBP); in masked hypertensive patients, -15.3±12.9/-9.3±9.5 mm Hg (n=1308, both P=0.000); and among white-coat hypertensive patients, 23.7±13.2/8.2±9.1 mm Hg (n=580, both P=0.000). Our results showed a difference of 5 mm Hg in SBP among sustained hypertensive patients, as recommended by the Japanese Society of Hypertension Guidelines for the Management of Hypertension; however, in other hypertensive patient types, the differences in SBP and DBP between office and home measurements differed by >5 mm Hg. Office and home BP measurements should be interpreted cautiously, keeping in mind the clinical setting.
authors.affiliation: Japanese Medical and Dental Practitioners for the Improvement of Medical Care, Tokyo, Japan.|Department of Clinical Research of Kanagawa Association of Medical and Dental Practitioners, Yokohama, Japan.
authors.forename: Hisao
authors.initials: H
authors.lastname: Mori
authors.affiliation: Japanese Medical and Dental Practitioners for the Improvement of Medical Care, Tokyo, Japan.|Department of Clinical Research of Kanagawa Association of Medical and Dental Practitioners, Yokohama, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ukai
authors.affiliation: Japanese Medical and Dental Practitioners for the Improvement of Medical Care, Tokyo, Japan.|Department of Clinical Research of Kanagawa Association of Medical and Dental Practitioners, Yokohama, Japan.
authors.forename: Hareaki
authors.initials: H
authors.lastname: Yamamoto
authors.affiliation: Japanese Medical and Dental Practitioners for the Improvement of Medical Care, Tokyo, Japan.|Department of Clinical Research of Kanagawa Association of Medical and Dental Practitioners, Yokohama, Japan.
authors.forename: Shouhei
authors.initials: S
authors.lastname: Yuasa
authors.affiliation: Japanese Medical and Dental Practitioners for the Improvement of Medical Care, Tokyo, Japan.|Department of Clinical Research of Kanagawa Association of Medical and Dental Practitioners, Yokohama, Japan.
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Suzuki
authors.affiliation: Japanese Medical and Dental Practitioners for the Improvement of Medical Care, Tokyo, Japan.|Department of Clinical Research of Kanagawa Association of Medical and Dental Practitioners, Yokohama, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Chin
authors.affiliation: Department of Clinical Research of Kanagawa Association of Medical and Dental Practitioners, Yokohama, Japan.
authors.forename: Takuma
authors.initials: T
authors.lastname: Katsumata
authors.affiliation: Yokohama Rousai Hospital, Japan Organization of Occupational Health and Safety, Yokohama, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Umemura
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D007564:Japan; D008297:Male; D008875:Middle Aged; D009819:Office Visits; D059466:White Coat Hypertension / Q000175:diagnosis* / Q000503:physiopathology