title: A dual-functional supramolecular hydrogel based on a spiropyran-galactose conjugate for target-mediated and light-controlled delivery of microRNA into cells.
abstract: A supramolecular hydrogel formed by spiropyran conjugated galactose was developed for light-controlled release of miR-122 and target-mediated delivery of the miRNA into HepG2 cells cultured on top of the gel.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Xiao
authors.initials: X
authors.lastname: Xiao
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Jing
authors.initials: J
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Xingxing
authors.initials: X
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Lei
authors.initials: L
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Jinbo
authors.initials: J
authors.lastname: Li
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. njuzy@nju.edu.cn jinboli@nju.edu.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D001578:Benzopyrans / Q000737:chemistry*; D016503:Drug Delivery Systems; D005690:Galactose / Q000737:chemistry*; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D008027:Light; D035683:MicroRNAs / Q000235:genetics*; D009574:Nitro Compounds / Q000737:chemistry*
chemical_list: D001578:Benzopyrans; D020100:Hydrogels; D007211:Indoles; D035683:MicroRNAs; D009574:Nitro Compounds; C088184:spiropyran; D005690:Galactose