title: Synthesis of Bifunctional Potassium Acyltrifluoroborates.
abstract: New bifunctional potassium acyltrifluoroborate (KAT) substrates have been synthesized in gram scale using optimized reaction conditions. Chemoselective transformation of functional groups in the presence of an acyltrifluoroborate has been demonstrated, and orthogonal reactions of bifunctional KAT reagents are reported. This allows for the incorporation of KAT moieties into peptides and dyes.
authors.affiliation: Laboratorium für Organische Chemie, Department of Chemistry and Applied Biosciences, ETH Zürich , 8093 Zürich, Switzerland.
authors.forename: Sizhou M
authors.initials: SM
authors.lastname: Liu
authors.affiliation: Laboratorium für Organische Chemie, Department of Chemistry and Applied Biosciences, ETH Zürich , 8093 Zürich, Switzerland.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Mazunin
authors.affiliation: Laboratorium für Organische Chemie, Department of Chemistry and Applied Biosciences, ETH Zürich , 8093 Zürich, Switzerland.
authors.forename: Vijaya R
authors.initials: VR
authors.lastname: Pattabiraman
authors.affiliation: Laboratorium für Organische Chemie, Department of Chemistry and Applied Biosciences, ETH Zürich , 8093 Zürich, Switzerland.
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Bode