title: Bacteriophages of Yersinia pestis.
abstract: Bacteriophage play many varied roles in microbial ecology and evolution. This chapter collates a vast body of knowledge and expertise on Yersinia pestis phages, including the history of their isolation and classical methods for their isolation and identification. The genomic diversity of Y. pestis phage and bacteriophage islands in the Y. pestis genome are also discussed because all phage research represents a branch of genetics. In addition, our knowledge of the receptors that are recognized by Y. pestis phage, advances in phage therapy for Y. pestis infections, the application of phage in the detection of Y. pestis, and clustered regularly interspaced short palindromic repeats (CRISPRs) sequences of Y. pestis from prophage DNA are all reviewed here.
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, No. Dongdajie, Fengtai, Beijing, 100071, China. xnazhao@163.com.
authors.forename: Xiangna
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Bacteriology and Immunology, Medicum, Research Programs Unit, University of Helsinki, Helsinki, 00014, Finland.
authors.forename: Mikael
authors.initials: M
authors.lastname: Skurnik
mesh_terms: D000818:Animals; D001435:Bacteriophages / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D064112:Clustered Regularly Interspaced Short Palindromic Repeats / Q000235:genetics; D014644:Genetic Variation; D044404:Genomic Islands; D006801:Humans; D039002:Prophages / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D011991:Receptors, Virus / Q000502:physiology; D015010:Yersinia pestis / Q000821:virology*
chemical_list: D011991:Receptors, Virus
keywords: Bacteriophages; Detection and treatment; Genomic diversity; Receptors; Yersinia pestis