title: Sequence-identification ofCandidaspecies isolated from candidemia.
abstract: BACKGROUND
  Candidaspecies are the most prevalent cause of invasive fungal infections such as candidemia. Candidemia is a lethal fungal infection among immunocompromised patients worldwide. Main pathogen isCandida albicansbut a global shift in epidemiology toward non-albicansspecies have reported. Species identification is imperative for good management of candidemia as a fatal infection. The aim of the study is to identifyCandidaspp. obtained from candidemia and determination of mortality rate among this population.
  
  
  METHODS
  The study was performed during February 2014 to March 2015 in Tehran, Iran. Two-hundred and four blood cultures were evaluated for fungal bloodstream infection. Identification of isolates was carried out using phenotypic tests and polymerase chain reaction sequencing technique.
  
  
  RESULTS
  Twenty-two out of 204 patients (10.8%) had candidemia.Candida parapsilosiswas the most prevalent species (45.4%), followed byC. albicans(31.8%) andCandida glabrata(22.7%). Male to female sex ratio was 8/14.
  
  
  CONCLUSIONS
  The emergence of resistant strains ofCandidaspecies should be considered by physicians to decrease the mortality of this fatal fungal infection by appropriate treatment.
authors.affiliation: Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Naeimeh
authors.initials: N
authors.lastname: Fathi
authors.affiliation: Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Rasoul
authors.initials: R
authors.lastname: Mohammadi
authors.affiliation: Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mohammad Amin
authors.initials: MA
authors.lastname: Tabatabaiefar
authors.affiliation: Department of Biology, School of Applied Sciences, Imam Hossein University, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Ghahri
authors.affiliation: Department of Biology, Ashkezar Branch, Islamic Azad University, Ashkezar, Yazd, Iran.
authors.forename: Seyedeh Zahra
authors.initials: SZ
authors.lastname: Sadrossadati
keywords: Candida parapsilosis; candidemia; sequencing