title: Visible-light-mediated generation of nitrile oxides for the photoredox synthesis of isoxazolines and isoxazoles.
abstract: Visible-light photoredox catalysis enables the synthesis of biologically relevant isoxazolines and isoxazoles from hydroxyimino acids. The process shows broad functional group compatibility and mechanistic and computational studies support a visible-light-mediated generation of nitrile oxides by two sequential oxidative single electron transfer processes.
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. daniele.leonori@manchester.ac.uk.
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Svejstrup
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. daniele.leonori@manchester.ac.uk.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Zawodny
authors.affiliation: AstraZeneca, Silk Road Business Park, Macclesfield SK10 2NA, UK.
authors.forename: James J
authors.initials: JJ
authors.lastname: Douglas
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. daniele.leonori@manchester.ac.uk.
authors.forename: Damon
authors.initials: D
authors.lastname: Bidgeli
authors.affiliation: Department of Chemistry, Faculty of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
authors.forename: Nadeem S
authors.initials: NS
authors.lastname: Sheikh
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK. daniele.leonori@manchester.ac.uk.
authors.forename: Daniele
authors.initials: D
authors.lastname: Leonori