title: Dopamine polymerization promoted by a catecholase biomimetic CuII(μ-OH)CuIIcomplex containing a triazine-based ligand.
abstract: We describe herein the catecholase-like catalytic activity and dopamine polymerization by using a dinuclear [LCuII(μ-OH)2CuII](ClO4)2(1) complex where L is the dinucleating triazine-based ligand 6-chloro-N2,N2,N4,N4-tetrakis(pyridin-2-ylmethyl)-1,3,5-triazine-2,4-diamine. The kinetic parameters (kcat= 0.318 s-1, KM= 1.6 × 10-3mol L-1, and kcat/KM= 198.8 L s-1mol-1), mechanistic insights into the oxidation of 3,5-di-tert-butyl catechol and early characterization of poly(dopamine) are presented.
authors.affiliation: Laboratório de Bioinorgânica e Cristalografia, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil. ademir.neves@ufsc.br adailton.bortoluzzi@ufsc.br.
authors.forename: José A F
authors.initials: JA
authors.lastname: de Oliveira
authors.affiliation: Laboratório de Bioinorgânica e Cristalografia, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil. ademir.neves@ufsc.br adailton.bortoluzzi@ufsc.br.
authors.forename: Marcos P
authors.initials: MP
authors.lastname: da Silva
authors.affiliation: Laboratório de Bioinorgânica e Cristalografia, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil. ademir.neves@ufsc.br adailton.bortoluzzi@ufsc.br.
authors.forename: Bernardo
authors.initials: B
authors.lastname: de Souza
authors.affiliation: Laboratório de Bioinorgânica e Cristalografia, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil. ademir.neves@ufsc.br adailton.bortoluzzi@ufsc.br.
authors.forename: Tiago P
authors.identifier: http://orcid.org/0000-0003-4789-266X
authors.initials: TP
authors.lastname: Camargo
authors.affiliation: Departamento de Química, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil.
authors.forename: Bruno
authors.initials: B
authors.lastname: Szpoganicz
authors.affiliation: Laboratório de Bioinorgânica e Cristalografia, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil. ademir.neves@ufsc.br adailton.bortoluzzi@ufsc.br.
authors.forename: Ademir
authors.initials: A
authors.lastname: Neves
authors.affiliation: Laboratório de Bioinorgânica e Cristalografia, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil. ademir.neves@ufsc.br adailton.bortoluzzi@ufsc.br.
authors.forename: Adailton J
authors.initials: AJ
authors.lastname: Bortoluzzi
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D004156:Catechol Oxidase / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties; D014227:Triazines / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D007211:Indoles; D008024:Ligands; D011108:Polymers; D014227:Triazines; C568283:polydopamine; D003300:Copper; D004156:Catechol Oxidase