title: Adenoidectomy can improve obstructive sleep apnoea in young children: systematic review and meta-analysis.
abstract: OBJECTIVE
  To systematically search for studies reporting outcomes for adenoidectomy alone as a treatment for paediatric obstructive sleep apnoea and use the data to perform a meta-analysis.
  
  
  METHODS
  Nine databases, including PubMed and Medline, were systematically searched through to 1 April 2016. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement was followed.
  
  
  RESULTS
  A total of 1032 articles were screened and 126 full texts were reviewed. Three paediatric studies (47 patients) reported outcomes. Overall, apnoea-hypopnoea index values decreased from 18.1 ± 16.8 to 3.1 ± 5.5 events per hour (28 patients). Random-effects modelling demonstrated a mean difference of -14.43 events per hour (I2 = 23 per cent (low inconsistency)). The apnoea-hypopnoea index standardised mean difference was -1.14 (large magnitude of effect). The largest reduction in apnoea-hypopnoea index was observed in children aged less than 12 months (reduction of 56.6-94.9 per cent). Lowest oxygen saturation values improved from 80.0 ± 9.5 to 85.5 ± 6.0 per cent (13 children).
  
  
  CONCLUSIONS
  Adenoidectomy alone has improved obstructive sleep apnoea in children, especially in those aged less than 12 months; however, given the low number of studies, isolated adenoidectomy remains an area for additional research.
authors.affiliation: Otolaryngology - Head and Neck Surgery,Tripler Army Medical Center,Honolulu,Hawaii,USA.
authors.forename: L K
authors.initials: LK
authors.lastname: Reckley
authors.affiliation: Otolaryngology - Head and Neck Surgery,Tripler Army Medical Center,Honolulu,Hawaii,USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Song
authors.affiliation: Otolaryngology - Head and Neck Surgery,Tripler Army Medical Center,Honolulu,Hawaii,USA.
authors.forename: E T
authors.initials: ET
authors.lastname: Chang
authors.affiliation: Otolaryngology - Head and Neck Surgery,Tripler Army Medical Center,Honolulu,Hawaii,USA.
authors.forename: B B
authors.initials: BB
authors.lastname: Cable
authors.affiliation: Department of Otorhinolaryngology/Sleep Medicine Centre,Hospital CUF,Porto,Portugal.
authors.forename: V
authors.initials: V
authors.lastname: Certal
authors.affiliation: Otolaryngology - Head and Neck Surgery,Tripler Army Medical Center,Honolulu,Hawaii,USA.
authors.forename: M
authors.initials: M
authors.lastname: Camacho
mesh_terms: D000233:Adenoidectomy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D020181:Sleep Apnea, Obstructive / Q000601:surgery*; D016896:Treatment Outcome
keywords:  Systematic; Adenoidectomy; Meta-Analysis; Review; Sleep Apnea Syndromes