title: Boronate based fluorescence (ESIPT) probe for peroxynitrite.
abstract: A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester "protecting" unit. The "protecting" unit of the probe is removed by peroxynitrite to "turn-on" ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off-on response towards peroxynitrite, in HeLa and RAW 264.7 cells.
authors.affiliation: Department of Chemistry, University of Bath, BA2 7AY, UK. T.D.James@bath.ac.uk.
authors.forename: Adam C
authors.initials: AC
authors.lastname: Sedgwick
authors.affiliation: Department of Chemistry, University of Bath, BA2 7AY, UK. T.D.James@bath.ac.uk.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Sun
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Gyoungmi
authors.initials: G
authors.lastname: Kim
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Juyoung
authors.initials: J
authors.lastname: Yoon
authors.affiliation: Department of Chemistry, University of Bath, BA2 7AY, UK. T.D.James@bath.ac.uk.
authors.forename: Steven D
authors.initials: SD
authors.lastname: Bull
authors.affiliation: Department of Chemistry, University of Bath, BA2 7AY, UK. T.D.James@bath.ac.uk.
authors.forename: Tony D
authors.identifier: http://orcid.org/0000-0002-4095-2191
authors.initials: TD
authors.lastname: James