title: Boston Type I Keratoprosthesis Implantation Following Autologous Submandibular Gland Transplantation for End Stage Ocular Surface Disorders.
abstract: OBJECTIVE
  To describe the results of Boston keratoprosthesis implantation in a patient with Stevens-Johnson syndrome following autologous submandibular gland transplantation.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  We report the case of a man diagnosed with Stevens-Johnson syndrome. Autologous submandibular gland transplantation was performed in the right eye in 2008 to ameliorate tear film deficiency. Due to the improvement in the microenvironment of the ocular surface, Boston keratoprosthesis implantation was performed in the right eye in 2011.
  
  
  RESULTS
  He maintained a VA of 20/100 for 12 months. At the last follow-up visit (54 months), his VA had declined to finger count level due to de novo glaucoma, which was treated with glaucoma drainage device implantation, cyclophotocoagulation and topical anti-glaucoma medications.
  
  
  CONCLUSIONS
  The procedures described provide patients with end-stage ocular surface disease an option to lessen the severity of keratoconjunctivitis sicca and to regain their VA.
authors.affiliation: a State Key Laboratory of Ophthalmology, Corneoplastic Unit , Zhongshan Ophthalmic Center, Sun Yat-sen University , Guangzhou , China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Gu
authors.affiliation: a State Key Laboratory of Ophthalmology, Corneoplastic Unit , Zhongshan Ophthalmic Center, Sun Yat-sen University , Guangzhou , China.
authors.forename: Jiajie
authors.initials: J
authors.lastname: Zhai
authors.affiliation: b Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology , Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University , Guangzhou , China.
authors.forename: Guiqing
authors.initials: G
authors.lastname: Liao
authors.affiliation: a State Key Laboratory of Ophthalmology, Corneoplastic Unit , Zhongshan Ophthalmic Center, Sun Yat-sen University , Guangzhou , China.
authors.forename: Jiaqi
authors.initials: J
authors.lastname: Chen
mesh_terms: D001187:Artificial Organs; D003315:Cornea; D003316:Corneal Diseases / Q000601:surgery*; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D013262:Stevens-Johnson Syndrome / Q000601:surgery*; D013363:Submandibular Gland / Q000637:transplantation*; D014182:Transplantation, Autologous; D014792:Visual Acuity / Q000502:physiology
keywords: Autologous submandibular gland transplantation; Boston keratoprosthesis; Stevens–Johnson syndrome; dry eye