title: Formal total synthesis of (±)-strictamine - the [2,3]-Stevens rearrangement for construction of octahydro-2H-2,8-methanoquinolizines.
abstract: For decades, akuammiline alkaloids have attracted synthetic chemists due to their intriguing molecular architecture. Among the different structural elements embedded in their carboskeleton, the methanoquinolizidine system constitutes the signature structural element of this alkaloid family. Herein, we describe a novel synthetic access to this system which relies on a [2,3]-Stevens rearrangement and results in the formal synthesis of strictamine.
authors.affiliation: Department of Chemistry, University of Konstanz, Universitätsstrasse 10, 78457 Konstanz, Germany. tanja.gaich@uni-konstanz.de.
authors.forename: Ruben
authors.initials: R
authors.lastname: Eckermann
authors.affiliation: Department of Chemistry, University of Konstanz, Universitätsstrasse 10, 78457 Konstanz, Germany. tanja.gaich@uni-konstanz.de.
authors.forename: Michael
authors.initials: M
authors.lastname: Breunig
authors.affiliation: Department of Chemistry, University of Konstanz, Universitätsstrasse 10, 78457 Konstanz, Germany. tanja.gaich@uni-konstanz.de.
authors.forename: Tanja
authors.initials: T
authors.lastname: Gaich