title: Surgical Strategy and Facial Nerve Outcomes in Petrous Bone Cholesteatoma.
abstract: To review the classification and management of petrous bone cholesteatomas (PBCs) at our center and the outcomes of facial nerve (FN) management in these lesions.
  
  
  
  This was a retrospective study. The setting was a quaternary referral center for skull base pathology in Italy. A total of 200 patients with 201 PBCs were included in the study. All patients diagnosed radiologically with PBCs were classified according to the Sanna classification. All patients were surgically treated and followed up with radiology. The main outcome measures - classification of PBCs, the surgical approach used, disease control, and FN outcomes - were analyzed.
  
  
  
  Supralabyrinthine PBCs were the most common type with 92 cases (45.8%) followed by the massive PBCs with 72 cases (35.8%). Preservation of preoperative FN function was highest in the infralabyrinthine (72.2%) and infralabyrinthine-apical (73.3%) types. The transotic approach was used in 66 cases (32.8%) in this series. The modified transcochlear approach type A was applied in 55 cases (27.3%). Active management of the nerve (rerouting, anastomosis, or grafting) was required in 53 cases (26.4%). Postoperatively, of the 116 cases with FN House-Brackmann grade I and II, 107 cases (92.2%) retained the same grade or improved. Recurrence was seen in 7 cases (3.5%). The mean duration of follow-up was 6.3 years.
  
  
  
  Radical disease clearance must take precedence over hearing and FN preservation in PBCs. Active FN management, including rerouting, end-to-end anastomosis, and cable nerve grafting, routinely come to play in the surgical management of PBCs, and the postoperative FN results after such interventions can be satisfactory in most cases.
authors.affiliation: Gruppo Otologico, Department of Otology and Skull Base Surgery, Piacenza, Italy.
authors.forename: Sampath Chandra
authors.initials: SC
authors.lastname: Prasad
authors.forename: Gianluca
authors.initials: G
authors.lastname: Piras
authors.forename: Enrico
authors.initials: E
authors.lastname: Piccirillo
authors.forename: Abdelkader
authors.initials: A
authors.lastname: Taibah
authors.forename: Alessandra
authors.initials: A
authors.lastname: Russo
authors.forename: Jingchun
authors.initials: J
authors.lastname: He
authors.forename: Mario
authors.initials: M
authors.lastname: Sanna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001847:Bone Diseases / Q000601:surgery*; D002648:Child; D002781:Cholesteatoma / Q000601:surgery*; D005154:Facial Nerve / Q000601:surgery; D005155:Facial Nerve Diseases / Q000453:epidemiology / Q000517:prevention & control* / Q000601:surgery; D020220:Facial Nerve Injuries / Q000453:epidemiology / Q000517:prevention & control* / Q000601:surgery; D005260:Female; D006309:Hearing; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D010579:Petrous Bone / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control* / Q000601:surgery; D012008:Recurrence; D012189:Retrospective Studies; D055815:Young Adult