title: Implementation of Arithmetic and Nonarithmetic Functions on a Label-free and DNA-based Platform.
abstract: A series of complex logic gates were constructed based on graphene oxide and DNA-templated silver nanoclusters to perform both arithmetic and nonarithmetic functions. For the purpose of satisfying the requirements of progressive computational complexity and cost-effectiveness, a label-free and universal platform was developed by integration of various functions, including half adder, half subtractor, multiplexer and demultiplexer. The label-free system avoided laborious modification of biomolecules. The designed DNA-based logic gates can be implemented with readout of near-infrared fluorescence, and exhibit great potential applications in the field of bioimaging as well as disease diagnosis.
authors.affiliation: Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Wang
authors.affiliation: Research Center for Analytical Sciences, College of Sciences, Northeastern University, Shenyang 110819, China.
authors.forename: Mengqi
authors.initials: M
authors.lastname: He
authors.affiliation: Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
authors.forename: Ronghuan
authors.initials: R
authors.lastname: He
authors.affiliation: Research Center for Analytical Sciences, College of Sciences, Northeastern University, Shenyang 110819, China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
mesh_terms: D039301:Computers, Molecular; D004247:DNA / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D008128:Logic; D055641:Mathematical Concepts; D053768:Metal Nanoparticles; D010087:Oxides / Q000737:chemistry; D012834:Silver / Q000737:chemistry
chemical_list: D010087:Oxides; D012834:Silver; D006108:Graphite; D004247:DNA