title: Basics and applications of genome editing technology.
abstract: Genome editing with programmable site-specific nucleases is an emerging technology that enables the manipulation of targeted genes in many organisms and cell lines. Since the development of the CRISPR-Cas9 system in 2012, genome editing has rapidly become an indispensable technology for all life science researchers, applicable in various fields. In this seminar, we will introduce the basics of genome editing and focus on the recent development of genome editing tools and technologies for the modification of various organisms and discuss future directions of the genome editing research field, from basic to medical applications.
authors.affiliation: Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University.
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Naoaki
authors.initials: N
authors.lastname: Sakamoto
mesh_terms: D000818:Animals; D064112:Clustered Regularly Interspaced Short Palindromic Repeats; D004247:DNA / Q000235:genetics; D000072669:Gene Editing; D016678:Genome; D006801:Humans
chemical_list: D004247:DNA