title: Enantioselective oxidative functionalization of the Csp3-H bond adjacent to a nitrogen atom for rapid access to β-hydroxyl-α-amino acid derivatives.
abstract: Highly chemoselective and enantioselective one-pot reactions involved in the oxidative functionalization of Csp3-H bonds adjacent to nitrogen atoms in N-aryl glycine esters were developed. The method provided rapid access to a variety of highly functionalized β-hydroxyl-α-amino acid derivatives from simple starting materials under mild conditions.
authors.affiliation: Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. syliu@sist.ecnu.edu.cn whu@chem.ecnu.edu.cn and Xiangya International Academy of Translational Medicine, Central South University, 172 Tongzipo Rd., Changsha, Hunan Province 410013, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Qiu
authors.affiliation: Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. syliu@sist.ecnu.edu.cn whu@chem.ecnu.edu.cn.
authors.forename: Xin
authors.initials: X
authors.lastname: Guo
authors.affiliation: Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. syliu@sist.ecnu.edu.cn whu@chem.ecnu.edu.cn.
authors.forename: Yu
authors.initials: Y
authors.lastname: Qian
authors.affiliation: Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. syliu@sist.ecnu.edu.cn whu@chem.ecnu.edu.cn.
authors.forename: Changcheng
authors.initials: C
authors.lastname: Jing
authors.affiliation: Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. syliu@sist.ecnu.edu.cn whu@chem.ecnu.edu.cn.
authors.forename: Chaoqun
authors.initials: C
authors.lastname: Ma
authors.affiliation: Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. syliu@sist.ecnu.edu.cn whu@chem.ecnu.edu.cn.
authors.forename: Shunying
authors.initials: S
authors.lastname: Liu
authors.affiliation: Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Rd., Shanghai, 200062, China. syliu@sist.ecnu.edu.cn whu@chem.ecnu.edu.cn.
authors.forename: Wenhao
authors.initials: W
authors.lastname: Hu