title: Merging photoredox with copper catalysis: decarboxylative difluoroacetylation of α,β-unsaturated carboxylic acids with ICF2CO2Et.
abstract: A photoredox-/copper-catalyzed decarboxylative difluoroacetylation reaction of α,β-unsaturated carboxylic acids has been developed. This reaction produces a variety of difluoroalkylated alkenes in moderate to excellent yields and exhibits satisfactory stereoselectivity and a broad substrate scope at ambient temperature. Furthermore, this decarboxylative difluoroacetylation protocol provides efficient and environment friendly access to the difluoroalkylated alkenes.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liuxuey@lzu.edu.cn.
authors.forename: Heng-Rui
authors.initials: HR
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liuxuey@lzu.edu.cn.
authors.forename: Dao-Qian
authors.initials: DQ
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liuxuey@lzu.edu.cn.
authors.forename: Ya-Ping
authors.initials: YP
authors.lastname: Han
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liuxuey@lzu.edu.cn.
authors.forename: Yi-Feng
authors.identifier: http://orcid.org/0000-0002-2747-9598
authors.initials: YF
authors.lastname: Qiu
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liuxuey@lzu.edu.cn.
authors.forename: Dong-Po
authors.initials: DP
authors.lastname: Jin
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liuxuey@lzu.edu.cn.
authors.forename: Xue-Yuan
authors.initials: XY
authors.lastname: Liu