title: The immunocompromised oncohematological critically ill patient: considerations in severe infections.
abstract: Sepsis and septic shock remain a major cause of mortality among critically ill patient. This is particularly relevant among cancer patients as highlighted by different series showing that up to one in five patients admitted to intensive care units (ICU) with sepsis have cancer, and also, sepsis is a leading reason for ICU admission in patients with cancer. The classic predictors of mortality among these patients (such as cancer lineage, neutropenia degree, or bone marrow transplantation history) have changed during the last decades, and they should no longer be used to rule out ICU admission. Instead, a newer approach to these patients should be performed taking into account organ failure assessment and prior performance status. When a doubt exists about the criteria for ICU admission, not only a trial of ICU management should be proposed to assert that no patients are withhold of the opportunity for recovering from the acute condition, but also an early admission, to prevent more derangement, and thus impact on mortality.
authors.affiliation: Department of Critical Care, Vall d' Hebron University Hospital, Barcelona, Spain;; Department of Medicine, Universitat Autónoma de Barcelona (UAB), Barcelona, Spain.
authors.forename: Belén
authors.initials: B
authors.lastname: Encina
authors.affiliation: Department of Medicine, Universitat Autónoma de Barcelona (UAB), Barcelona, Spain;; Department of Critical Care, Hospital Especialidades Médicas de la Salud, San Luis Potosí, México.
authors.forename: Leonel
authors.initials: L
authors.lastname: Lagunes
authors.affiliation: Department of Critical Care, Hospital de Sabadell - Parc Taulí Universitary Health Corporation, Barcelona, Spain.
authors.forename: Marc
authors.initials: M
authors.lastname: Morales-Codina
keywords: Sepsis; critically ill; hematological; immunocompromised; oncological; septic shock