title: Tuft Cells: New Players in Colitis.
abstract: A recent surge of interest in tuft cells, which are chemosensory intestinal epithelial cells, has uncovered new functional roles for these cells in colorectal cancer, metabolic signaling, and type 2 immunity. Here, we explore emerging evidence suggesting that tuft cells are critical for protection during enteric infections and inflammatory responses.
authors.affiliation: Department of Medicine, Division of Infectious Disease, University of Virginia, Charlottesville, VA 22908, USA.
authors.forename: Shaun P
authors.initials: SP
authors.lastname: Steele
authors.affiliation: Department of Medicine, Division of Infectious Disease, University of Virginia, Charlottesville, VA 22908, USA.
authors.forename: Stephanie J
authors.initials: SJ
authors.lastname: Melchor
authors.affiliation: Department of Medicine, Division of Infectious Disease, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: wap3g@virginia.edu.
authors.forename: William A
authors.initials: WA
authors.lastname: Petri
mesh_terms: D000818:Animals; D016360:Clostridioides difficile / Q000276:immunology; D003092:Colitis / Q000276:immunology* / Q000382:microbiology / Q000469:parasitology / Q000473:pathology*; D004761:Enterocolitis, Pseudomembranous / Q000150:complications / Q000276:immunology / Q000473:pathology; D004847:Epithelial Cells / Q000276:immunology / Q000382:microbiology / Q000469:parasitology / Q000473:pathology; D006373:Helminthiasis / Q000150:complications / Q000276:immunology / Q000473:pathology; D006376:Helminths / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D007413:Intestinal Mucosa / Q000276:immunology* / Q000382:microbiology / Q000469:parasitology / Q000473:pathology*; D007422:Intestines / Q000276:immunology / Q000382:microbiology / Q000469:parasitology / Q000473:pathology; D015398:Signal Transduction