title: Neuroinflammation in liver disease: sessional talks from ISHEN.
abstract: At the recent ISHEN ('International Symposium of Hepatic Encephalopathy & Nitrogen Metabolism') conference in London, a whole session was dedicated to our increasing awareness of the importance of inflammation in the brain - termed 'neuroinflammation', in the development of Hepatic Encephalopathy (HE) - the neurological manifestations of advanced liver disease. In this review our ISHEN speakers further discuss the content of their sessional presentations and more broadly we discuss our understanding of the role of neuroinflammation in HE pathogenesis.
authors.affiliation: Gastroenterology Department, Basildon & Thurrock University Hospitals, Basildon, UK. Gavin.Wright@btuh.nhs.uk.|Hepatology and Hepatobiliary Medicine, The Royal Free Hospital, Pond Street, London, NW3 2QG, UK. Gavin.Wright@btuh.nhs.uk.|University College London, Gower Street, London, WC1E 6BT, UK. Gavin.Wright@btuh.nhs.uk.
authors.forename: Gavin
authors.initials: G
authors.lastname: Wright
authors.affiliation: Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Canada.
authors.forename: Mark
authors.initials: M
authors.lastname: Swain
authors.affiliation: INSERM CIC IT 805, CHU Paris IdF Ouest - Hôpital Raymond Poincaré, 104 boulevard Raymond Poincaré, 92380, Garches, France.
authors.forename: Djillali
authors.initials: D
authors.lastname: Annane
authors.affiliation: Centre Hépato-Biliaire, Hôpital Paul Brousse, 12, avenue Paul vaillant Couturier, 94800, Villejuif, France.
authors.forename: Faouzi
authors.initials: F
authors.lastname: Saliba
authors.affiliation: GHU Paris-Sud - Hôpital Paul Brousse, 12 avenue Paul Vaillant-Couturier, 94804, Villejuif Cedex, France.
authors.forename: Didier
authors.initials: D
authors.lastname: Samuel
authors.affiliation: Liver Unit, Instiute of Digestive and Metabolic Diseases, Hopsital Clinic, University of Barcelona, Barcelona, Spain.
authors.forename: Vicente
authors.initials: V
authors.lastname: Arroyo
authors.affiliation: Department of Internal Medicine, Central Texas Veterans Healthcare System, VA Bld 205, 1901 South 1st Street, Temple, TX, 76504, USA.
authors.forename: Sharon
authors.initials: S
authors.lastname: DeMorrow
authors.affiliation: Departement of Hepatology, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Copenhagen, Denmark.
authors.forename: Anne
authors.initials: A
authors.lastname: Witt
mesh_terms: D000818:Animals; D001812:Blood-Brain Barrier / Q000378:metabolism / Q000473:pathology; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D003226:Congresses as Topic; D006501:Hepatic Encephalopathy / Q000453:epidemiology / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000453:epidemiology / Q000378:metabolism* / Q000473:pathology; D018836:Inflammation Mediators / Q000378:metabolism*; D038622:Internationality; D008107:Liver Diseases / Q000378:metabolism / Q000473:pathology
chemical_list: D018836:Inflammation Mediators
keywords: Ammonia; Cerebral Heamodynamics; Compensatory Antiinflammatory responses; Liver failure; Neuroinflammation; Systemic inflammatory responses