title: Senescence and Cancer: In the Name of Immunosuppression.
abstract: Senescent cells and cancer cells recruit immunosuppressive myeloid cells. In this issue of Cancer Cell, Eggert et al. report that senescent cells recruit immature myeloid cells (iMCs) through the secretion of the CCL2 cytokine and that these iMCs have pro- or anti-tumorigenic activities, depending on the cellular context.
authors.affiliation: Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain. Electronic address: sllanos@cnio.es.
authors.forename: Susana
authors.initials: S
authors.lastname: Llanos
authors.affiliation: Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain. Electronic address: mserrano@cnio.es.
authors.forename: Manuel
authors.initials: M
authors.lastname: Serrano
mesh_terms: D016922:Cellular Senescence; D016207:Cytokines; D006801:Humans; D007108:Immune Tolerance; D022423:Myeloid Cells; D009369:Neoplasms
chemical_list: D016207:Cytokines