title: Platelet-rich fibrin: a boon in regenerative endodontics.
abstract: Research into regenerative dentistry has contributed momentum to the field of molecular biology. Periapical surgery aims at removing periapical pathology to achieve complete wound healing and regeneration of bone and periodontal tissue. Regenerative endodontic procedures are widely being added to the current armamentarium of pulp therapy procedures. The regenerative potential of platelets has been deliberated. Platelet-rich fibrin (PRF) is a wonderful tissue-engineering product and has recently gained much popularity due its promising results in wound healing bone induction. The features of this product are an attribute of platelets which, after cellular interactions, release growth factors and have shown application in diverse disciplines of dentistry. This paper is intended to shed light onto the various prospects of PRF and to provide clinical insight into regenerative endodontic therapy.
authors.affiliation: Department of Periodontology, Vasantdada Patil Dental College and Hospital, Kavalapur, India - drshouvik@rediffmail.com.
authors.forename: Priyanka D
authors.initials: PD
authors.lastname: Rebentish
authors.forename: Girish
authors.initials: G
authors.lastname: Umashetty
authors.forename: Harpreet
authors.initials: H
authors.lastname: Kaur
authors.forename: Trupthi
authors.initials: T
authors.lastname: Doizode
authors.forename: Mithun
authors.initials: M
authors.lastname: Kaslekar
authors.forename: Shouvik
authors.initials: S
authors.lastname: Chowdhury
mesh_terms: D001691:Biological Therapy / Q000379:methods*; D001792:Blood Platelets / Q000737:chemistry; D004708:Endodontics / Q000379:methods*; D005337:Fibrin / Q000494:pharmacology / Q000627:therapeutic use*; D048091:Guided Tissue Regeneration / Q000379:methods*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage; D059630:Mesenchymal Stem Cells / Q000187:drug effects; D018919:Neovascularization, Physiologic; D010485:Periapical Periodontitis / Q000628:therapy; D044968:Regenerative Medicine / Q000379:methods*; D014945:Wound Healing
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D005337:Fibrin