title: Virucide properties of cold atmospheric plasma for future clinical applications.
abstract: Cold atmospheric plasma (CAP) has been repeatedly identified to bear powerful microbicidal efficacy on bacteria including multidrug resistant organisms and fungi on non-living surfaces, in biofilms as well as on contaminated and infected tissues. CAP furthermore was found to stimulate wound healing in chronic wounds and exerted anti-neoplastic effects on numerous tumor entities. Thus, CAP represents a promising medical tool for many clinical and therapeutic issues. Studies about CAP effects on virus particles recently were in arrears, but to date increasingly move into the focus of interest. Apparently, CAP treatment is followed by a promising virus inactivation and contributes to tissue regeneration. Here we review the current state of science concerning the so far investigated CAP effects on different virus species and virus-associated disorders. J. Med. Virol. 89:952-959, 2017. © 2017 Wiley Periodicals, Inc.
authors.affiliation: Department of Gynecology and Obstetrics, University Medicine Tübingen, Tübingen, Germany.|Department of Urology, University Medicine Greifswald, Greifswald, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Weiss
authors.affiliation: Department of Dermatology, University Medicine Greifswald, Greifswald, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Daeschlein
authors.affiliation: Department of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Kramer
authors.affiliation: Department of Urology, University Medicine Greifswald, Greifswald, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Burchardt
authors.affiliation: Department of Gynecology and Obstetrics, University Medicine Tübingen, Tübingen, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Brucker
authors.affiliation: Department of Gynecology and Obstetrics, University Medicine Tübingen, Tübingen, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Wallwiener
authors.affiliation: Department of Urology, University Medicine Greifswald, Greifswald, Germany.
authors.forename: M B
authors.initials: MB
authors.lastname: Stope
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D050296:Microbial Viability / Q000187:drug effects*; D058626:Plasma Gases / Q000494:pharmacology*; D014771:Virion / Q000187:drug effects*; D038301:Virus Inactivation
chemical_list: D000890:Anti-Infective Agents; D058626:Plasma Gases
keywords: CAP; cold atmospheric plasma; virus; virus inactivation; virus-associated disorders