title: Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs: An Update.
abstract: After beta lactam antibiotics, hypersensitivity reactions to nonsteroidal antiinflammatory drugs are the second cause of hypersensitivity to drugs. Acute manifestations affect the respiratory tract (aspirin exacerbated respiratory disease), the skin (urticaria and angioedema), or are generalized (anaphylaxis). Correct diagnosis and treatment in order to prevent unnecessary morbidity and the potential risk of death from these severe reactions, and to provide proper medical advice on future drug use frequently requires the participation of allergology specialists familiar with these clinical conditions.
authors.affiliation: Allergy and Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela. sanchezbmario@gmail.com.
authors.forename: Mario
authors.initials: M
authors.lastname: Sánchez-Borges
authors.affiliation: Allergy and Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela. fercab@cantv.net.
authors.forename: Fernan
authors.initials: F
authors.lastname: Caballero-Fonseca
authors.affiliation: Allergy and Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela. arnaldocapriles@gmail.com.
authors.forename: Arnaldo
authors.initials: A
authors.lastname: Capriles-Hulett
authors.affiliation: Dermatology Service, Centro Médico de Caracas, Caracas, Venezuela. lagaveledo@gmail.com.
authors.forename: Luis
authors.initials: L
authors.lastname: González-Aveledo
keywords: anaphylaxis; asthma; drug reactions; non steroidal anti-inflammatory drugs (NSAIDs); urticaria and angioedema