title: Fabrication of multifunctional CaP-TC composite coatings and the corrosion protection they provide for magnesium alloys.
abstract: Two major problems with magnesium (Mg) alloy biomaterials are the poor corrosion resistance and infection associated with implantation. In this study, a novel calcium phosphate (CaP)/tetracycline (TC) composite coating for Mg implants that can both improve the corrosion resistance of Mg and release a drug in a durable way is reported. Scanning electron microscope (SEM) images showed that TC additives make the CaP coating more compact and uniform. Electrochemical tests indicated CaP/TC coatings can provide excellent corrosion protection for Mg alloy substrates. Besides, TC additives can also provide effective prevention of bone infection and inflammation due to its broad-spectrum antibacterial properties. The one-step hydrothermal process reported here greatly simplified the multi-step fabrication of smart coatings reported previously.
authors.affiliation: .
authors.forename: Cui
authors.initials: C
authors.lastname: Tan
authors.affiliation: .
authors.forename: Xiaoxu
authors.initials: X
authors.lastname: Zhang
authors.affiliation: .
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
mesh_terms: D000497:Alloys / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003343:Corrosion; D006801:Humans; D008274:Magnesium / Q000737:chemistry*; D019736:Prostheses and Implants / Q000592:standards*
chemical_list: D000497:Alloys; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; C020243:calcium phosphate; D008274:Magnesium
keywords: Mg alloys; antibacterial; biomaterials; corrosion