title: An Update on Biomedical Application of Nanotechnology for Alzheimer's Disease Diagnosis and Therapy.
abstract: Approximately 35 million people worldwide suffer from Alzheimer's disease (AD). The cellular uptake and specific transport of drugs and imaging agents to brain are common issues in the diagnosis and therapy of AD. New advances in nanotechnology have supplied favorable solutions to this issue. Various nanocarriers such as polymeric nanoparticles, liposomes, micelles, dendrimers and nanogels have been studied for the delivery of drugs and imaging agents to brain. This review presents a succinct discussion of the applications of nanotechnology for Alzheimer's disease diagnosis and therapy.
authors.affiliation: Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
authors.forename: Y
authors.initials: Y
authors.lastname: Panahi
authors.affiliation: Department of Chemistry, Shahrood Branch, Islamic Azad University, Shahrood, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Mohammadhosseini
authors.affiliation: Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: A J N
authors.initials: AJ
authors.lastname: Abadi
authors.affiliation: Stem Cell Research Center,Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Akbarzadeh
authors.affiliation: Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: H
authors.initials: H
authors.lastname: Mellatyar
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy*; D050091:Dendrimers / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems / Q000379:methods; D006801:Humans; D008081:Liposomes / Q000737:chemistry; D053758:Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods; D011108:Polymers / Q000737:chemistry
chemical_list: D050091:Dendrimers; D004337:Drug Carriers; D008081:Liposomes; D011108:Polymers