title: Programmable Real-time Clinical Photoacoustic and Ultrasound Imaging System.
abstract: Photoacoustic imaging has attracted interest for its capacity to capture functional spectral information with high spatial and temporal resolution in biological tissues. Several photoacoustic imaging systems have been commercialized recently, but they are variously limited by non-clinically relevant designs, immobility, single anatomical utility (e.g., breast only), or non-programmable interfaces. Here, we present a real-time clinical photoacoustic and ultrasound imaging system which consists of an FDA-approved clinical ultrasound system integrated with a portable laser. The system is completely programmable, has an intuitive user interface, and can be adapted for different applications by switching handheld imaging probes with various transducer types. The customizable photoacoustic and ultrasound imaging system is intended to meet the diverse needs of medical researchers performing both clinical and preclinical photoacoustic studies.
authors.affiliation: Departments of Creative IT Engineering and Electrical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
authors.forename: Jeesu
authors.initials: J
authors.lastname: Kim
authors.affiliation: Departments of Creative IT Engineering and Electrical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
authors.forename: Sara
authors.initials: S
authors.lastname: Park
authors.affiliation: Departments of Creative IT Engineering and Electrical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
authors.forename: Yuhan
authors.initials: Y
authors.lastname: Jung
authors.affiliation: Alpinion Medical Systems, 72 Digital-Ro 26-Gil, Guro-Gu, Seoul, 08393, Republic of Korea.
authors.forename: Sunyeob
authors.initials: S
authors.lastname: Chang
authors.affiliation: Alpinion Medical Systems, 72 Digital-Ro 26-Gil, Guro-Gu, Seoul, 08393, Republic of Korea.
authors.forename: Jinyong
authors.initials: J
authors.lastname: Park
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, United States of America.
authors.forename: Yumiao
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, United States of America.
authors.forename: Jonathan F
authors.initials: JF
authors.lastname: Lovell
authors.affiliation: Departments of Creative IT Engineering and Electrical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
authors.forename: Chulhong
authors.initials: C
authors.lastname: Kim
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000000981:diagnostic imaging; D002645:Chickens; D003199:Computer Systems; D003287:Contrast Media; D004867:Equipment Design; D005260:Female; D041981:Gastrointestinal Tract / Q000000981:diagnostic imaging; D006801:Humans; D053844:Lasers, Solid-State; D049329:Nanostructures; D019047:Phantoms, Imaging; D061088:Photoacoustic Techniques / Q000295:instrumentation*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012984:Software; D014159:Transducers; D014463:Ultrasonography / Q000295:instrumentation*; D014584:User-Computer Interface
chemical_list: D003287:Contrast Media