title: Sleep duration, daytime napping, markers of obstructive sleep apnea and stroke in a population of southern China.
abstract: Sleep habits are associated with stroke in western populations, but this relation has been rarely investigated in China. Moreover, the differences among stroke subtypes remain unclear. This study aimed to explore the associations of total stroke, including ischemic and hemorrhagic type, with sleep habits of a population in southern China. We performed a case-control study in patients admitted to the hospital with first stroke and community control subjects. A total of 333 patients (n = 223, 67.0%, with ischemic stroke; n = 110, 23.0%, with hemorrhagic stroke) and 547 controls were enrolled in the study. Participants completed a structured questionnaire to identify sleep habits and other stroke risk factors. Least absolute shrinkage and selection operator (Lasso) and multiple logistic regression were performed to identify risk factors of disease. Incidence of stroke, and its subtypes, was significantly associated with snorting/gasping, snoring, sleep duration, and daytime napping. Snorting/gasping was identified as an important risk factor in the Lasso logistic regression model (Lasso' β = 0.84), and the result was proven to be robust. This study showed the association between stroke and sleep habits in the southern Chinese population and might help in better detecting important sleep-related factors for stroke risk.
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Wen
authors.affiliation: Department of Sports, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Fu-Hua
authors.initials: FH
authors.lastname: Pi
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Pi
authors.initials: P
authors.lastname: Guo
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Wen-Ya
authors.initials: WY
authors.lastname: Dong
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Yu-Qing
authors.initials: YQ
authors.lastname: Xie
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Xiang-Yu
authors.initials: XY
authors.lastname: Wang
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Fang-Fang
authors.initials: FF
authors.lastname: Xia
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Shao-Jie
authors.initials: SJ
authors.lastname: Pang
authors.affiliation: Department of neurology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Yan-Chun
authors.initials: YC
authors.lastname: Wu
authors.affiliation: Department of neurology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Wang
authors.affiliation: Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China.
authors.forename: Qing-Ying
authors.initials: QY
authors.lastname: Zhang
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D002681:China; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000208:ethnology / Q000503:physiopathology; D000070263:Sleep Hygiene / Q000145:classification / Q000502:physiology; D012913:Snoring / Q000175:diagnosis* / Q000208:ethnology / Q000503:physiopathology; D020521:Stroke / Q000145:classification / Q000175:diagnosis* / Q000208:ethnology / Q000503:physiopathology; D011795:Surveys and Questionnaires