title: Post-bleaching sensitivity in patients with sickle cell disease.
abstract: Sickle cell disease (SCD) is a monogenic disease that affects millions of people worldwide. This study analyzed the effectiveness of bleaching and tooth sensitivity after in-office bleaching in patients with SCD. Forty volunteers were randomly assigned to four groups of 10 patients each (five with the SCD and five healthy controls) and treated using in-office bleaching with 35% hydrogen peroxide and different light activation protocols. No statistically significant difference was observed with relation to presence of tooth sensitivity, with or without use of a source of light for peroxide activation, and all bleaching therapies were effective, regardless of the technique employed and the presence/absence of sickle cell disease. The data showed that in-office dental bleaching is a viable alternative for improvement of oral esthetics for patients with SCD.
authors.affiliation: Department of Dentistry, Hemocentro de Alagoas, Brazil. gmlgat@uol.com.br.
authors.forename: Guacyra M
authors.initials: GM
authors.lastname: Lisboa
authors.affiliation: Department of Hematology, Hemocentro de Alagoas, Brazil.
authors.forename: Verónica L
authors.initials: VL
authors.lastname: Guedes
authors.affiliation: Department of Dentistry, Laboratório Central de Saúde Pública de Alagoas, Brazil.
authors.forename: Maria do R Ml
authors.initials: MD
authors.lastname: Luna
authors.affiliation: Department of Dentistry, Instituto de Atendimento e Estudos Odontológicos do Nordeste, Alagoas, Brazil.
authors.forename: Américo M
authors.initials: AM
authors.lastname: Carneiro
authors.affiliation: Department of Dental Prosthesis, School of Dentistry, University of São Paulo, Brasil.
authors.forename: Roberto C
authors.initials: RC
authors.lastname: Stegun
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications; D003807:Dentin Sensitivity / Q000209:etiology; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D014073:Tooth Bleaching; D055815:Young Adult
chemical_list: D006861:Hydrogen Peroxide
keywords: Esthetics; hydrogen peroxide; tooth bleaching