title: Rate of Retinal Detachment after Early Prophylactic Vitrectomy for Acute Retinal Necrosis.
abstract: OBJECTIVE
  To compare the rate of retinal detachment after acute retinal necrosis in eyes that underwent early vitrectomy versus no early vitrectomy.
  
  
  METHODS
  Charts of patients (61 eyes) who presented to Texas Retina Associates between January 1, 2006 and December 30, 2014 for acute retinal necrosis were reviewed. Charts with incomplete documentation or follow-up less than 6 months were excluded. Twenty-nine remaining eyes were divided into two groups: early vitrectomy and no early vitrectomy. Primary outcome measure was rate of retinal detachment.
  
  
  RESULTS
  Out of 29 eyes, 12 underwent early vitrectomy within 30 days of diagnosis and 17 either underwent vitrectomy after 30 days or did not undergo prophylactic vitrectomy at all. Three out of 12 eyes (25%) developed retinal detachment in the early vitrectomy group versus 10 out of 17 eyes (59%) in the no early vitrectomy group (p = 0.076).
  
  
  CONCLUSIONS
  Early vitrectomy within 30 days may prevent retinal detachment after acute retinal necrosis.
authors.affiliation: a Department of Ophthalmology , The University of Texas Southwestern Medical Center , Dallas , TX , Texas, USA.
authors.forename: Jason Mingyi
authors.initials: JM
authors.lastname: Huang
authors.affiliation: b University of St. Andrews, St. Andrews , Fife , UK.
authors.forename: Patrick
authors.initials: P
authors.lastname: Callanan
authors.affiliation: c Texas Retina Associates , Dallas , Texas , USA.
authors.forename: David
authors.initials: D
authors.lastname: Callanan
authors.affiliation: c Texas Retina Associates , Dallas , Texas , USA.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D006563:Herpes Zoster Ophthalmicus / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D006801:Humans; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000175:diagnosis / Q000517:prevention & control*; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy; D055815:Young Adult
keywords: Acute retinal necrosis; prophylactic vitrectomy; retinal detachment; visual acuity