title: Patient-reported outcomes and aesthetic evaluation of root coverage procedures: a 12-month follow-up of a randomized controlled clinical trial.
abstract: To assess patient-reported outcome measures (PROMs), aesthetics and stability of root coverage procedures from a previous 6-month RCT after 1 year.
  
  
  
  Forty-five patients (90 recessions) had received a coronally advanced flap (CAF = control) only or a xenogeneic collagen matrix in addition (CAF + CMX = test). Visual analogue scales (VAS) and questionnaires were used for PROMs and the root coverage aesthetic score (RES) for professional aesthetic evaluations.
  
  
  
  VAS scores (patient satisfaction) amounted to 8.58 ± 1.86 (test) versus 8.38 ± 2.46 (control). Six patients preferred CAF + CMX concerning surgical procedure and aesthetics, six preferred CAF and 29 were equally satisfied. RES was 7.85 ± 2.42 for the test group versus 7.34 ± 2.90 for the controls. Root coverage (RC) was 76.28% for test and 75.05% for control defects. The mean increase in keratinized tissue width was higher in test (from 1.97 to 3.02 mm) than in controls (from 2.00 to 2.64 mm) (p = 0.0413). Likewise, test sites showed more gain in gingival thickness (0.52 mm) than control sites (0.27 mm) (p = 0.0023). Compared to 6 months, clinical outcomes were stable.
  
  
  
  Results for PROMs, RES and RC did not significantly differ between treatment groups. Thickness and width of keratinized tissue were enhanced following CAF + CMX compared to CAF alone.
authors.affiliation: Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Stefanini
authors.affiliation: Department of Periodontology, University of Bonn, Bonn, Germany.
authors.forename: Karin
authors.initials: K
authors.lastname: Jepsen
authors.affiliation: Department of Periodontology, Vita Salute San Raffaele University of Milan, Milan, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: de Sanctis
authors.affiliation: Department of Periodontology, University of Siena, Siena, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Baldini
authors.affiliation: Private Practice, Hamburg, Germany.
authors.forename: Björn
authors.initials: B
authors.lastname: Greven
authors.affiliation: Private Practice, Hamburg, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Heinz
authors.affiliation: Department of Periodontology, the Sahlgrenska Academy University of Gothenburg, Gothenburg, Sweden.
authors.forename: Jan
authors.initials: J
authors.lastname: Wennström
authors.affiliation: Department of Periodontology, the Sahlgrenska Academy University of Gothenburg, Gothenburg, Sweden.
authors.forename: Björn
authors.initials: B
authors.lastname: Cassel
authors.affiliation: Department of Periodontology, University of Madrid, Madrid, Spain.
authors.forename: Fabio
authors.initials: F
authors.lastname: Vignoletti
authors.affiliation: Department of Periodontology, University of Madrid, Madrid, Spain.
authors.forename: Mariano
authors.initials: M
authors.lastname: Sanz
authors.affiliation: Department of Periodontology, University of Bonn, Bonn, Germany.
authors.forename: Søren
authors.initials: S
authors.lastname: Jepsen
authors.affiliation: Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Zucchelli
mesh_terms: D003238:Connective Tissue; D004955:Esthetics, Dental; D005500:Follow-Up Studies; D005889:Gingival Recession; D006801:Humans; D000071066:Patient Reported Outcome Measures; D016896:Treatment Outcome
keywords: aesthetics; collagen (matrix); gingival recession; keratinized tissue; patient-centred outcomes; patient-reported outcomes; root coverage; tissue regeneration; xenograft