title: Gene Regulation: Activation through Space.
abstract: A recent study visualizes nascent RNAs in live Drosophila embryos to establish a connection between enhancer strength and the frequency of transcriptional bursts. Interestingly, one enhancer can simultaneously activate two core promoters, challenging models of enhancer-core-promoter communication via direct protein-protein contacts.
authors.affiliation: Research Institute of Molecular Pathology, Vienna Biocenter, Dr. Bohr-Gasse 7, 1030 Vienna, Austria.
authors.forename: Felix
authors.initials: F
authors.lastname: Muerdter
authors.affiliation: Research Institute of Molecular Pathology, Vienna Biocenter, Dr. Bohr-Gasse 7, 1030 Vienna, Austria. Electronic address: stark@starklab.org.
authors.forename: Alexander
authors.initials: A
authors.lastname: Stark
mesh_terms: D000818:Animals; D004330:Drosophila / Q000235:genetics*; D029721:Drosophila Proteins / Q000235:genetics; D004742:Enhancer Elements, Genetic; D005786:Gene Expression Regulation; D011401:Promoter Regions, Genetic; D015533:Transcriptional Activation
chemical_list: D029721:Drosophila Proteins