title: Biological Control of Mosquito Vectors: Past, Present, and Future.
abstract: Mosquitoes represent the major arthropod vectors of human disease worldwide transmitting malaria, lymphatic ﬁlariasis, and arboviruses such as dengue virus and Zika virus. Unfortunately, no treatment (in the form of vaccines or drugs) is available for most of these diseases andvectorcontrolisstillthemainformofprevention. Thelimitationsoftraditionalinsecticide-based strategies, particularly the development of insecticide resistance, have resulted in signiﬁcant efforts to develop alternative eco-friendly methods. Biocontrol strategies aim to be sustainable and target a range of different mosquito species to reduce the current reliance on insecticide-based mosquito control. In thisreview, weoutline non-insecticide basedstrategiesthat havebeenimplemented orare currently being tested. We also highlight the use of mosquito behavioural knowledge that can be exploited for control strategies.
authors.affiliation: Insect Behaviour Group, Department of Agriculture, Food and Environment, University of Pisa, Pisa 56124, Italy. benelli.giovanni@gmail.com.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Benelli
authors.affiliation: Department of Disease Control, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK. claire.jeffries@lshtm.ac.uk.
authors.forename: Claire L
authors.initials: CL
authors.lastname: Jeffries
authors.affiliation: Department of Disease Control, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK. thomas.walker@lshtm.ac.uk.
authors.forename: Thomas
authors.initials: T
authors.lastname: Walker
keywords: Wolbachia bacteria; arboviruses; boosted SIT (Sterile Insect Technique); copepods; larvivorous ﬁshes; mosquito-borne diseases; sex pheromones; sound traps; sterile insect technique; swarm manipulation