title: Omalizumab in the Treatment of Chronic Inducible Urticaria.
abstract: Omalizumab is a recombinant humanized monoclonal antibody that inhibits immunoglobulin E. It has been approved for the treatment of severe asthma and chronic spontaneous urticaria refractory to other treatments. Its use in the management of chronic inducible urticaria (a type triggered by certain stimuli) is still considered off-label, although this use has been discussed in some consensus papers. This review brings together case reports and case series describing the use of omalizumab to treat chronic inducible urticaria. We analyze the most important aspects of the cases and the outcomes reported. The results seem to position omalizumab as a potentially effective, safe treatment alternative in some cases of chronic inducible urticaria.
authors.affiliation: Servicio de Dermatología, Hospital Universitario de La Princesa, Madrid, España. Electronic address: somniem@gmail.com.
authors.forename: P
authors.initials: P
authors.lastname: Chicharro
authors.affiliation: Servicio de Dermatología, Hospital Universitario de La Princesa, Madrid, España.
authors.forename: P
authors.initials: P
authors.lastname: Rodríguez
authors.affiliation: Servicio de Dermatología, Hospital Universitario de La Princesa, Madrid, España.
authors.forename: D
authors.initials: D
authors.lastname: de Argila
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D008297:Male; D008875:Middle Aged; D000069444:Omalizumab / Q000627:therapeutic use*; D010812:Physical Stimulation / Q000009:adverse effects; D014581:Urticaria / Q000188:drug therapy* / Q000209:etiology; D055815:Young Adult
chemical_list: D000069444:Omalizumab; D007073:Immunoglobulin E
keywords: Cholinergic urticaria; Chronic inducible urticaria; Cold urticaria; Delayed pressure urticaria; Heat urticaria; Omalizumab; Solar urticaria; Urticaria colinérgica; Urticaria crónica inducible; Urticaria por calor; Urticaria por frío; Urticaria por presión retardada; Urticaria solar