title: [Hospitalization rate in relation to severe complications of transrectal prostate biopsy: About 2715 patients biopsied].
abstract: OBJECTIVE
  To identify hospitalizations directly related to a complication occurring within 30 days following a transrectal prostate biopsy (PBP).
  
  
  OBJECTIVE
  Overall hospitalization rates, mortality rates, potential predisposing factors for complications.
  
  
  METHODS
  Single-center study including all patients who underwent PBP between January 2005 and January 2012. Any hospitalization occurring within 30 days of the PBP for urgent motive was considered potentially attributable to biopsy. We identified the reason for hospitalization with direct complications (urinary infection or fever, rectal bleeding, bladder caillotage, retention) and indirect (underlying comorbidities decompensation) of the biopsy. The contributing factors were anticoagulant or antiplatelet treatment well as waning immunity factors (corticosteroid therapy, HIV, chemotherapy or immunodulateur).
  
  
  RESULTS
  Among 2715 men who underwent PBP, there were 120 (4.4%) hospitalizations including 28 (1.03%) caused by the biopsy. Twenty-five (0.92%) were related to a direct complication of biopsy: 14 (56%) for urinary tract infection or fever including 1 hospitalization in intensive care, 5 (20%) for rectal bleeding which required several transfusions 1, 10 (40%) urinary retention and 3 (0.11%) for an indirect complication (2 coronary syndromes and 1 respiratory failure). Several direct complications were associated in 3 cases. Only two hospitalizations associated with rectal bleeding were taking an antiplatelet or anticoagulant. There was no association between hospitalization for urinary tract infections and a decreased immune status. The first death observed in our study occurred at D31 of pulmonary embolism (advanced metastatic patient with bladder cancer). Twenty (60.6%) patients urgently hospitalized did not have prostate cancer.
  
  
  CONCLUSIONS
  Within this large sample of patients the overall rate of hospitalization due to the realization of a PBP was 1%. It has not been found predictive of complications leading to hospitalization.
  
  
  METHODS
  4.
authors.affiliation: Service urologie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. Electronic address: blandine.tamarelle@chu-lyon.fr.
authors.forename: B
authors.initials: B
authors.lastname: Tamarelle
authors.affiliation: Service urologie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. Electronic address: paul.perrin@chu-lyon.fr.
authors.forename: P
authors.initials: P
authors.lastname: Perrin
authors.affiliation: Service urologie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. Electronic address: marian.devonec@chu-lyon.fr.
authors.forename: M
authors.initials: M
authors.lastname: Devonec
authors.affiliation: Service urologie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. Electronic address: philippe.paparel@chu-lyon.fr.
authors.forename: P
authors.initials: P
authors.lastname: Paparel
authors.affiliation: Service urologie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. Electronic address: alain.ruffion@chu-lyon.fr.
authors.forename: A
authors.initials: A
authors.lastname: Ruffion
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000009:adverse effects / Q000379:methods; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology*; D011467:Prostate / Q000473:pathology*; D012007:Rectum; D012720:Severity of Illness Index
keywords: Biopsie; Biopsy; Cancer; Causes; Complication; Hospitalisation; Hospitalization; Morbidity; Morbidité; Prostate