title: A susceptibility locus for classical Hodgkin lymphoma at 8q24 near MYC/PVT1 predicts patient outcome in two independent cohorts.
authors.affiliation: Department of Haematology, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.|Centre de Recherche en Cancérologie de Lyon - INSERM U 1052/CNRS UMR 5286/Centre Léon Bérard, Lyon, France.|Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: Hervé
authors.initials: H
authors.lastname: Ghesquières
authors.affiliation: Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: Beth R
authors.initials: BR
authors.lastname: Larrabee
authors.affiliation: Department of Haematology, Hôpital Le Bocage-CHU Dijon, Dijon, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Casasnovas
authors.affiliation: Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Maurer
authors.affiliation: International Agency for Research on Cancer (IARC), Lyon, France.
authors.forename: James D
authors.initials: JD
authors.lastname: McKay
authors.affiliation: Division of Haematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Ansell
authors.affiliation: MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
authors.forename: Dorothy
authors.initials: D
authors.lastname: Montgomery
authors.affiliation: Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: Yan W
authors.initials: YW
authors.lastname: Asmann
authors.affiliation: MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
authors.forename: Katrina
authors.initials: K
authors.lastname: Farrell
authors.affiliation: Centre de Recherche en Cancérologie de Lyon - INSERM U 1052/CNRS UMR 5286/Centre Léon Bérard, Lyon, France.
authors.forename: Aurélie
authors.initials: A
authors.lastname: Verney
authors.affiliation: Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: Susan L
authors.initials: SL
authors.lastname: Slager
authors.affiliation: Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: Cristine
authors.initials: C
authors.lastname: Allmer
authors.affiliation: Department of Haematology, CHU Nancy-Brabois, Vandoeuvre, France.
authors.forename: Aurore
authors.initials: A
authors.lastname: Perrot
authors.affiliation: Department of Haematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker, Paris, France.
authors.forename: Richard
authors.initials: R
authors.lastname: Delarue
authors.affiliation: Division of Haematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Habermann
authors.affiliation: Lymphoid Malignancies Unit, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP) and University Paris Est, Créteil, France.
authors.forename: Jehan
authors.initials: J
authors.lastname: Dupuis
authors.affiliation: University of Iowa, Holden Comprehensive Cancer Center, Iowa City, IA, USA.
authors.forename: Brian K
authors.initials: BK
authors.lastname: Link
authors.affiliation: Department of Pathology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker, Paris, France.
authors.forename: Danielle
authors.initials: D
authors.lastname: Canioni
authors.affiliation: Department of Laboratory Medicine and Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Dogan
authors.affiliation: USC Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.
authors.forename: Wendy
authors.initials: W
authors.lastname: Cozen
authors.affiliation: MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
authors.forename: Ruth F
authors.initials: RF
authors.lastname: Jarrett
authors.affiliation: Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
authors.forename: James R
authors.initials: JR
authors.lastname: Cerhan
authors.affiliation: Department of Haematology, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.|Centre de Recherche en Cancérologie de Lyon - INSERM U 1052/CNRS UMR 5286/Centre Léon Bérard, Lyon, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Salles
mesh_terms: D002898:Chromosomes, Human, Pair 8; D016259:Genes, myc; D056426:Genetic Loci; D020022:Genetic Predisposition to Disease; D006689:Hodgkin Disease / Q000235:genetics* / Q000401:mortality*; D006801:Humans; D007976:Leupeptins; D020641:Polymorphism, Single Nucleotide; D011379:Prognosis; D062085:RNA, Long Noncoding; D016019:Survival Analysis
chemical_list: D007976:Leupeptins; C521123:PVT1 long-non-coding RNA, human; D062085:RNA, Long Noncoding; C063261:acetylleucyl-leucyl-norleucinal
keywords: 
  
  MYC
  
  ; 
  PVT1
  ; Hodgkin lymphoma; polymorphism; prognostic; susceptibility