title: Lymphomas-Part 1.
abstract: Primary central nervous system lymphomas are aggressive, high-cell-density tumors. There is recent increase in their incidence in immunocompetent patients. Knowledge of imaging findings on computed tomography and conventional MR imaging is important to suggest the diagnosis. Moreover, information obtained from advanced MR imaging techniques, such as diffusion-weighted imaging, diffusion tensor imaging, MR spectroscopy, perfusion-weighted imaging, and dynamic contrast-enhanced studies, increases diagnostic confidence and helps distinguish them from other aggressive intracranial tumors. This article discusses typical imaging findings of primary and secondary central nervous system lymphomas on computed tomography and conventional MR imaging, advanced MR imaging techniques, and changes related to steroid therapy.
authors.affiliation: Radiologic Department, Clínica Felippe Mattoso, Fleury Medicina Diagnóstica, Avenida das Américas 700, sala 320, Barra Da Tijuca, Rio De Janeiro, Rio De Janeiro CEP 22640-100, Brazil; Radiologic Department, Clínica IRM-Ressonância Magnética, Rua Capitão Salomão, Humaitá, Rio De Janeiro, Rio De Janeiro CEP 22271-040, Brazil. Electronic address: larabrandao.rad@terra.com.br.
authors.forename: Lara A
authors.initials: LA
authors.lastname: Brandão
authors.affiliation: Division of Neuroradiology, Department of Radiology, University of North Carolina School of Medicine, Room 3326, Old Infirmary Building, Manning Drive, Chapel Hill, NC 27599-7510, USA.
authors.forename: Mauricio
authors.initials: M
authors.lastname: Castillo
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging*; D009682:Magnetic Resonance Spectroscopy; D059906:Neuroimaging / Q000379:methods*; D014057:Tomography, X-Ray Computed
keywords: CNS lymphoma; Diffusion tensor imaging; Diffusion-weighted imaging; Dynamic contrast enhanced MR imaging; Imaging findings in lymphoma; MR spectroscopy; Perfusion-weighted imaging; Posttreatment evaluation