title: HIV and Bone Complications: Understudied Populations and New Management Strategies.
abstract: The higher risk of osteoporosis and fracture associated with HIV infection and certain antiretrovirals has been well established and the need for risk stratification among older adults increasingly recognized. This review focuses upon emerging data on bone complications with HIV/HCV coinfection, in children and adolescents, and with pre-exposure prophylaxis (PrEP), as well as new management strategies to minimize the negative effects of ART on bone.
authors.affiliation: Division of Infectious Diseases, Columbia University Medical Center, 630 w168th street PH8-876, New York, NY, 10032, USA. mty4@cumc.columbia.edu.
authors.forename: Michael T
authors.initials: MT
authors.lastname: Yin
authors.affiliation: Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University, 1830 East Monument Street, Suite 333, Baltimore, MD, 21287, USA.
authors.forename: Todd T
authors.initials: TT
authors.lastname: Brown
mesh_terms: D015519:Bone Density; D060085:Coinfection; D050723:Fractures, Bone / Q000517:prevention & control*; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D010024:Osteoporosis / Q000139:chemically induced / Q000276:immunology* / Q000503:physiopathology; D012307:Risk Factors
keywords: Bone; Bone loss; Bone mineral density; Children and adolescents; Fracture; HIV/HCV coinfection; Osteoporosis; Peak bone mass; PrEP; Tenofovir