title: A TRIM16-Galactin3 Complex Mediates Autophagy of Damaged Endomembranes.
abstract: Selective autophagy, an essential process for maintaining intracellular homeostasis, depends on precise target recognition and local activation. Reporting in Developmental Cell, Chauhan et al. (2016) elegantly demonstrate that interaction between TRIM16 and Galectin3 orchestrates the recruitment of core autophagic factors and activates selective autophagy at the site of damaged endomembranes.
authors.affiliation: Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
authors.forename: Milana
authors.initials: M
authors.lastname: Fraiberg
authors.affiliation: Department of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: zvulun.elazar@weizmann.ac.il.
authors.forename: Zvulun
authors.initials: Z
authors.lastname: Elazar
mesh_terms: D001343:Autophagy; D006706:Homeostasis; D006801:Humans