title: Short-term and middle-term evaluation of laparoscopic hepatectomies compared with open hepatectomies: A propensity score matching analysis.
abstract: OBJECTIVE
  To compare short-term results between laparoscopic hepatectomy and open hepatectomy using a propensity score matching.
  
  
  METHODS
  A patient in the laparoscopic liver resection (LLR) group was randomly matched with another patient in the open liver resection (OLR) group using a 1:1 allocated ratio with the nearest estimated propensity score. Patients of the LLR group without matches were excluded. Matching criteria included age, gender, body mass index, American Society of Anesthesiologists score, potential co-morbidities, hepatopathies, size and number of nodules, preoperative chemotherapy, minor or major liver resections. Intraoperative and postoperative data were compared in both groups.
  
  
  RESULTS
  From January 2012 to January 2015, a total of 241 hepatectomies were consecutively performed, of which 169 in the OLR group (70.1%) and 72 in the LLR group (29.9%). The conversion rate was 9.7% (n= 7). The mortality rate was 4.2% in the OLR group and 0% in the LLR group. Prior to and after propensity score matching, there was a statistically significant difference favorable to the LLR group regarding shorter operative times (185 minvs247.5 min;P= 0.002), less blood loss (100 mLvs300 mL;P= 0.002), a shorter hospital stay (7 dvs9 d;P= 0.004), and a significantly lower rate of medical complications (4.3%vs26.4%;P< 0.001).
  
  
  CONCLUSIONS
  Laparoscopic liver resections seem to yield better short-term and mid-term results as compared to open hepatectomies and could well be considered a privileged approach and become the gold standard in carefully selected patients.
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Untereiner
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Cagnet
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Memeo
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Vito
authors.initials: V
authors.lastname: De Blasi
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Stylianos
authors.initials: S
authors.lastname: Tzedakis
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Tullio
authors.initials: T
authors.lastname: Piardi
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Francois
authors.initials: F
authors.lastname: Severac
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Didier
authors.initials: D
authors.lastname: Mutter
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Reza
authors.initials: R
authors.lastname: Kianmanesh
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Marescaux
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Daniele
authors.initials: D
authors.lastname: Sommacale
authors.affiliation: Xavier Untereiner, Riccardo Memeo, Vito De Blasi, Stylianos Tzedakis, Francois Severac, Didier Mutter, Jacques Marescaux, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Strasbourg, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Pessaux
keywords: Colorectal metastases; Hepatocellular carcinoma; Laparoscopic hepatectomy; Liver resection; Morbidity and mortality; Open hepatectomy; Propensity score matching