title: Enantiospecific Aluminum-Catalyzed (3+2) Cycloaddition of Unactivated Aziridines with Isothiocyanates.
abstract: An Al(salen)Cl efficiently catalyzed the enantiospecific (3+2) cycloaddition of unactivated chiral aziridines with isothiocyanates to furnish functionalized iminothiazolidines at room temperature with 94-99% ee. The use of an aluminum Lewis acid as the catalyst, high enantiomeric purities, mild reaction conditions, broad substrate scope, and the high atom economy are the significant practical features.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati , Guwahati 781039, India.
authors.forename: Mani
authors.initials: M
authors.lastname: Sengoden
authors.affiliation: Department Chemistry, Graduate School of Science and Technology, Kumamoto University , 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Irie
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati , Guwahati 781039, India.
authors.forename: Tharmalingam
authors.initials: T
authors.lastname: Punniyamurthy