title: Pigmented Pindborg tumor of the maxilla: A case report.
abstract: The calcifying epithelial odontogenic tumor (CEOT), also known as the Pindborg tumor, is a benign locally invasive neoplasm. Common variants of CEOT include noncalcifying, Langerhans cell, bone and cementum forming and clear cell, which have a prognostic significance. Pigmented variants are known to occur in other odontogenic tumors. However, a definitive pigmented variant of CEOT has not been reported in literature so far. Here, we report the first case of pigmented Pindborg tumor arising from the maxilla in a young female. The pigment was demonstrated as melanin by staining and confirmed by immunohistochemistry. The pigmented variant of CEOT did not recur within 18 months postsurgery. Our report indicates that it is essential to recognize the pigmented variant. We discuss the common variants of CEOT and potential histogenesis of the pigmented variant. Further studies are required to reveal the histogenesis of melanocytes and their pathological significance in the odontogenic tumors.
authors.affiliation: Department of Pathology, Metropolis Healthcare Ltd., Chennai, India.
authors.forename: Subashchandrabose
authors.initials: S
authors.lastname: Priya
authors.affiliation: Department of Pathology, Metropolis Healthcare Ltd., Chennai, India.
authors.forename: Lakshmikanth Ramiah
authors.initials: LR
authors.lastname: Madanagopaal
authors.affiliation: Department of Pathology, Chennai Medical College Hospital and Research Centre, Trichy, Tamil Nadu, India.
authors.forename: Venkaterwaran
authors.initials: V
authors.lastname: Sarada
keywords: Calcifying epithelial odontogenic tumor; melanin; odontogenic tumors; pigmented Pindborg tumor