title: Amine Catalysis for the Organocatalytic Diboration of Challenging Alkenes.
abstract: The generation of in situ sp2-sp3diboron adducts has revolutionised the synthesis of organoboranes. Organocatalytic diboration reactions have represented a milestone in terms of unpredictable reactivity of these adducts. However, current methodologies have limitations in terms of substrate scope, selectivity and functional group tolerance. Here a new methodology based on the use of simple amines as catalyst is reported. This methodology provides a completely selective transformation overcoming current substrate scope and functional/protecting group limitations. Mechanistic studies have been included in this report.
authors.affiliation: Department of Chemistry, University of Hull, Cottingham Road, HU6 7RX, Hull, UK.
authors.forename: Albert
authors.initials: A
authors.lastname: Farre
authors.affiliation: Department of Chemistry, University of Hull, Cottingham Road, HU6 7RX, Hull, UK.
authors.forename: Kaline
authors.initials: K
authors.lastname: Soares
authors.affiliation: Department of Chemistry, University of Hull, Cottingham Road, HU6 7RX, Hull, UK.
authors.forename: Rachel A
authors.initials: RA
authors.lastname: Briggs
authors.affiliation: Department of Chemistry, University of Hull, Cottingham Road, HU6 7RX, Hull, UK.
authors.forename: Angelica
authors.initials: A
authors.lastname: Balanta
authors.affiliation: Department of Chemistry, University of Hull, Cottingham Road, HU6 7RX, Hull, UK.
authors.forename: David M
authors.initials: DM
authors.lastname: Benoit
authors.affiliation: Department of Chemistry, University of Hull, Cottingham Road, HU6 7RX, Hull, UK.
authors.forename: Amadeu
authors.identifier: http://orcid.org/0000-0001-8978-8647
authors.initials: A
authors.lastname: Bonet
keywords: Lewis base; amines; density functional calculations; organoboron; organocatalysis