title: Physical activity and lung function decline in adults with asthma: The HUNT Study.
abstract: People with asthma may seek advice about physical activity. However, the benefits of leisure time physical activity on lung function are unclear. We investigated the association between leisure time physical activity and lung function decline in adults with asthma.
  
  
  
  In a population-based cohort study in Norway, we used multiple linear regressions to estimate the annual mean decline in lung function (and 95% CI) in 1329 people with asthma over a mean follow-up of 11.6 years. The durations of light and hard physical activity per week in the last year were collected by questionnaire. Inactive participants did not report any light or hard activity, while active participants reported light or hard activity.
  
  
  
  The mean decline in forced expiratory volume in 1 s (FEV1) was 37 mL/year among inactive participants and 32 mL/year in active participants (difference: -5 mL/year (95% CI: -13 to 3)). The mean decline in forced vital capacity (FVC) was 33 mL/year among inactive participants and 31 mL/year in active participants (difference: -2 mL/year (95% CI: -11 to 7)). The mean decline in FEV1/FVC ratio was 0.36%/year among inactive participants and 0.22%/year in active participants (difference: -0.14%/year (95% CI: -0.27 to -0.01)). The mean decline in peak expiratory flow (PEF) was 14 mL/year among the inactive participants and 10 mL/year in active participants (difference: -4 mL/year (95% CI: -9 to 1)).
  
  
  
  We observed slightly less decline in lung function in physically active than inactive participants with asthma, particularly for FEV1, FEV1/FVC ratio and PEF.
authors.affiliation: Faculty of Medicine, Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Ben M
authors.initials: BM
authors.lastname: Brumpton
authors.affiliation: Faculty of Medicine, Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Arnulf
authors.initials: A
authors.lastname: Langhammer
authors.affiliation: Department of Circulation and Medical Imaging NTNU, Norwegian University of Science and Technology, Trondheim, Norway.|Department of Thoracic and Occupational Medicine, Trondheim University Hospital, Trondheim, Norway.
authors.forename: Anne H
authors.initials: AH
authors.lastname: Henriksen
authors.affiliation: Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.|Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Camargo
authors.affiliation: Faculty of Medicine, School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada.
authors.forename: Yue
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Faculty of Medicine, Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Pål R
authors.initials: PR
authors.lastname: Romundstad
authors.affiliation: Faculty of Medicine, Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Mai
mesh_terms: D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D015331:Cohort Studies; D018450:Disease Progression; D015444:Exercise / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D005541:Forced Expiratory Volume; D006801:Humans; D007899:Leisure Activities; D008297:Male; D008875:Middle Aged; D009664:Norway; D005082:Physical Exertion; D057185:Sedentary Behavior; D011795:Surveys and Questionnaires; D014797:Vital Capacity
keywords: forced expiratory volume in 1 s; forced vital capacity; leisure time; peak expiratory flow; prospective