title: Interaction between common antibiotics and a Shewanella strain isolated from an enhanced biological phosphorus removal activated sludge system.
abstract: With increasing production and consumption, more antibiotics are discharged into wastewater treatment plants and generally cannot be sufficiently removed. Because of the complexities of biological treatment processes, the fates of antibiotics and their effects on microorganisms, particularly those involved in the phosphorus removal system, are still unclear. Here, a Shewanella strain was isolated from an enhanced biological phosphorus removal (EBPR) system and was found to have the ability to remove phosphorus (P) and chemical oxygen demand (CODcr). Antibiotics affected the Shewanella strain through metabolism of the three main intracellular polymers, altering the ability of the strain to remove P and CODcr. These effects varied with the structure and concentration of the antibiotics. The Shewanella strain removed cefalexin and amoxicillin by degradation or adsorption, producing 2-hydroxy-3-phenyl pyrazine from cefalexin. This study enabled the recognition of the effect and removal of antibiotics during wastewater treatment.
authors.affiliation: School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Hang
authors.initials: H
authors.lastname: Liu
authors.affiliation: School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Yongkui
authors.initials: Y
authors.lastname: Yang
authors.affiliation: School of Environmental Science and Safety Engineering, Tianjin University of Technology, Tianjin 300384, China.
authors.forename: Yanhui
authors.initials: Y
authors.lastname: Ge
authors.affiliation: School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China. Electronic address: zhaolin@tju.edu.cn.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhao
authors.affiliation: School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Sha
authors.initials: S
authors.lastname: Long
authors.affiliation: School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Ruochun
authors.initials: R
authors.lastname: Zhang
mesh_terms: D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics*; D057919:Biological Oxygen Demand Analysis; D002506:Cephalexin / Q000493:pharmacokinetics; D010758:Phosphorus / Q000302:isolation & purification / Q000378:metabolism*; D012722:Sewage / Q000737:chemistry / Q000382:microbiology*; D020592:Shewanella / Q000187:drug effects / Q000302:isolation & purification / Q000378:metabolism*; D014865:Waste Disposal, Fluid / Q000379:methods*; D062065:Wastewater / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics
chemical_list: D000900:Anti-Bacterial Agents; D002506:Cephalexin; D010758:Phosphorus; D012722:Sewage; D062065:Wastewater; D014874:Water Pollutants, Chemical
keywords: Antibiotics; Biodegradation; Intracellular polymers; Nutrient removal; Shewanella