title: A novel type of cosavirus from children with nonpolio acute flaccid paralysis.
abstract: Human cosavirus (HCoSV) is a genus recently identified in the family Picornaviridae, which contains important pathogens to human health. Here, a novel type of HCoSV strain, cosavirus-zj-1 (GenBank no. KX545380), was identified in the fecal sample of a child with nonpolio acute flaccid paralysis (AFP) in China. Phylogenetic and sequence analyses suggested that this virus strain belonged to a new genotype in HCoSV B species. Our data show that surveillance of HCoSV is necessary for detecting viral agents in children with AFP, despite being the low detection rate.
authors.affiliation: The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, China. jszj_yangyan@sina.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Clinical Laboratory, Women and Children's Hospital of Huadu District, Guangzhou, Guangdong, 510800, China.
authors.forename: Aiping
authors.initials: A
authors.lastname: Ju
authors.affiliation: The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, China.
authors.forename: Xiaofen
authors.initials: X
authors.lastname: Xu
authors.affiliation: The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, China.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Cao
authors.affiliation: The Fourth Affiliated Hospital of Jiangsu University, 20 Zhengdong Road, Zhenjiang, Jiangsu, 212001, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Tao
mesh_terms: D002675:Child, Preschool; D002681:China; D016000:Cluster Analysis; D005243:Feces / Q000821:virology; D005838:Genotype; D006801:Humans; D010264:Paraplegia / Q000821:virology*; D010802:Phylogeny; D010849:Picornaviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D010850:Picornaviridae Infections / Q000821:virology*; D017422:Sequence Analysis, DNA
keywords: Complete genome; Human cosavirus; Phylogenetic analysis