title: Cross-cultural adaptation and validation of the disease specific questionnaire OQLQ in Serbian patients with malocclusions.
abstract: BACKGROUND
  Dentofacial disorders may potentially significantly affect the quality of life. Objectives of this study were to validate translated and culturally adapted Orthognatic Quality of Life Questionnaire (OQLQ) on a cohort of Serbian patients with malocclusions.
  
  
  METHODS
  The questionnaire was validated in 111 consecutive patients with malocclusions, seen between December 2014 and February 2015 at the Clinic of Orthodontics, Faculty of Dental Medicine, University of Belgrade. Clinical validity was assessed comparing the mean scores for the four subscales of the OQLQ and mean PAR pre-treatment score. In order to assess whether the allocation of items in the subscales corresponds to their distribution in the original questionnaire, an exploratory factor analysis (principal component analysis with varimax rotation) was conducted.
  
  
  RESULTS
  The results of the internal consistency analysis demonstrated good relationships between the items; Cronbach's alpha coefficients for the four subscales were highly significant (p<0.001) (0.88-0.91). All items were significantly correlated between baseline and the retest (6 weeks after). The correlations between the PAR and all four domains of the OQLQ were all significant (p<0.01). The loading weights obtained in the exploratory factor analysis showed that this model revealed four factors with eigenvalue greater than 1, explaining the 64.0% of the cumulative variance. The majority of the items (86.4%) in the Serbian version of the OQLQ presented the highest loading weight in the subscales assigned by the OQLQ developer.
  
  
  CONCLUSIONS
  The psychometric properties of the OQLQ (Serbian version) have exceptional internal consistency and reproducibility as an instrument for evaluation of dental malocclusions. Additionally, this questionnaire may be useful as a supplementary outcome measure in persons with malocclusions.
authors.affiliation: University of Belgrade, Faculty of Medicine, Institute of Epidemiology, Visegradska 26A, 11000 Belgrade, Serbia.
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Vucic
authors.affiliation: University of Belgrade, Faculty of Medicine, Institute of Epidemiology, Visegradska 26A, 11000 Belgrade, Serbia.
authors.forename: Branislav
authors.initials: B
authors.lastname: Glisic
authors.affiliation: University of Belgrade, Faculty of Medicine, Institute of Epidemiology, Visegradska 26A, 11000 Belgrade, Serbia.
authors.forename: Darija
authors.initials: D
authors.lastname: Kisic-Tepavcevic
authors.affiliation: University of Belgrade, Faculty of Medicine, Institute of Epidemiology, Visegradska 26A, 11000 Belgrade, Serbia.
authors.forename: Uros
authors.initials: U
authors.lastname: Vucic
authors.affiliation: University of Belgrade, Faculty of Medicine, Institute of Epidemiology, Visegradska 26A, 11000 Belgrade, Serbia.
authors.forename: Jelena
authors.initials: J
authors.lastname: Drulovic
authors.affiliation: University of Belgrade, Faculty of Medicine, Institute of Epidemiology, Visegradska 26A, 11000 Belgrade, Serbia.
authors.forename: Tatjana
authors.initials: T
authors.lastname: Pekmezovic
keywords: OQLQ; malocclusions; quality of life; validation