title: A Two-Step Method for Transferring Single-Walled Carbon Nanotubes onto a Hydrogel Substrate.
abstract: Carbon nanotube (CNT)-hydrogel nanocomposites are beneficial for various biomedical applications, such as nerve regeneration, tissue engineering, sensing, or implant coatings. Still, there are impediments to developing nanocomposites, including attaining a homogeneous CNT-polymer dispersion or patterning CNTs on hydrogels. While few approaches have been reported for patterning CNTs on polymeric substrates, these methods include high temperature, high vacuum or utilize a sacrificial layer and, hence, are incompatible with hydrogels as they lead to irreversible collapse in hydrogel structure. In this study, a novel two-step method is designed to transfer CNTs onto hydrogels. First, dense CNTs are grown on quartz substrates. Subsequently, hydrogel solutions are deposited on the quartz-grown CNTs. Upon gelation, the hydrogel with transferred CNTs is peeled from the quartz. Successful transfer is confirmed by scanning electron microscopy and indirectly by cell attachment. The efficient transfer is attributed to π-interactions pregelation between the polymers in solution and the CNTs.
authors.affiliation: Department of Biomedical Engineering, 3507 Lindell Blvd, St. Louis, MO, 63103, USA.
authors.forename: Mozhdeh
authors.initials: M
authors.lastname: Imaninezhad
authors.affiliation: Department of Physics, 3511 Laclede Ave, Saint Louis, MO, 63103, USA.
authors.forename: Irma
authors.initials: I
authors.lastname: Kuljanishvili
authors.affiliation: Department of Biomedical Engineering, 3507 Lindell Blvd, St. Louis, MO, 63103, USA.
authors.forename: Silviya Petrova
authors.initials: SP
authors.lastname: Zustiak
mesh_terms: D000818:Animals; D006801:Humans; D020100:Hydrogels / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D008855:Microscopy, Electron, Scanning; D053761:Nanocomposites / Q000008:administration & dosage / Q000737:chemistry / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D016716:PC12 Cells; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D051381:Rats; D023822:Tissue Engineering
chemical_list: D020100:Hydrogels; D037742:Nanotubes, Carbon; D011108:Polymers
keywords: biomaterials; carbon nanotubes; hydrogels; nanocomposites; polyacrylamide; polyethylene glycol