title: Status epilepticus: Using antioxidant agents as alternative therapies.
abstract: The epileptic state, or status epilepticus (SE), is the most serious situation manifested by individuals with epilepsy, and SE events can lead to neuronal damage. An understanding of the molecular, biochemical and physiopathological mechanisms involved in this type of neurological disease will enable the identification of specific central targets, through which novel agents may act and be useful as SE therapies. Currently, studies have focused on the association between oxidative stress and SE, the most severe epileptic condition. A number of these studies have suggested the use of antioxidant compounds as alternative therapies or adjuvant treatments for the epileptic state.
authors.affiliation: Laboratory of Neurosciences, National Institute of Pediatrics, Mexico City 04530, Mexico.
authors.forename: Liliana
authors.initials: L
authors.lastname: Carmona-Aparicio
authors.affiliation: Laboratory of Physiology of The Reticular Formation Reticular, National Institute of Neurology and Neurosurgery, Mexico City 14269, Mexico.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Zavala-Tecuapetla
authors.affiliation: Laboratory of Neuropharmacology of Natural Products, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
authors.forename: María Eva
authors.initials: ME
authors.lastname: González-Trujano
authors.affiliation: Department of Comparative Biology, Faculty of Sciences, National Autonomous University of Mexico, Mexico City 04150, Mexico.
authors.forename: Aristides Iii
authors.initials: AI
authors.lastname: Sampieri
authors.affiliation: Services of Endocrinology, National Institute of Pediatrics, Mexico City 04530, Mexico.
authors.forename: Hortencia
authors.initials: H
authors.lastname: Montesinos-Correa
authors.affiliation: Laboratory of Neurosciences, National Institute of Pediatrics, Mexico City 04530, Mexico.
authors.forename: Leticia
authors.initials: L
authors.lastname: Granados-Rojas
authors.affiliation: Military School of Graduate of Health, Multidisciplinary Research Laboratory, Secretariat of National Defense, Mexico City 11270, Mexico.
authors.forename: Esaú
authors.initials: E
authors.lastname: Floriano-Sánchez
authors.affiliation: Laboratory of Neurosciences, National Institute of Pediatrics, Mexico City 04530, Mexico.
authors.forename: Elvia
authors.initials: E
authors.lastname: Coballase-Urrutía
authors.affiliation: Laboratory of Neurosciences, National Institute of Pediatrics, Mexico City 04530, Mexico.
authors.forename: Noemí
authors.initials: N
authors.lastname: Cárdenas-Rodríguez
keywords: antioxidant agents; epilepsy; epileptic state; oxidative stress