title: Enantioselective synthesis of β-substituted chiral allylic amines via Rh-catalyzed asymmetric hydrogenation.
abstract: An asymmetric mono-hydrogenation of 2-acetamido-1,3-dienes catalyzed by a Rh-DuanPhos complex has been developed. This approach provides easy access to chiral allylic amines with excellent enantioselectivities and high regioselectivities. The products are valuable chiral building blocks for pharmaceuticals.
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, China. huilv@whu.edu.cn xumu@whu.edu.cn.
authors.forename: Qingli
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, China. huilv@whu.edu.cn xumu@whu.edu.cn.
authors.forename: Wenchao
authors.initials: W
authors.lastname: Gao
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, China. huilv@whu.edu.cn xumu@whu.edu.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Lv
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, China. huilv@whu.edu.cn xumu@whu.edu.cn and Department of Chemistry, South University of Science and Technology of China, Shenzhen, Guangdong 518055, China.
authors.forename: Xumu
authors.initials: X
authors.lastname: Zhang