title: Feasibility of a low concentration test bolus in CT angiography.
abstract: OBJECTIVE
  To investigate the feasibility of using a low-concentration test bolus in abdominal aorta computed tomography (CT) angiography (CTA).
  
  
  METHODS
  In 10 patients referred for CTA of the abdominal aorta with a body mass index (BMI) ≤28 kg/m2, a standard test bolus of 10 ml contrast medium (CM; 350 mg iodine/ml) was compared with a low-concentration test bolus (5 ml CM; 350 mg iodine/ml; 1:1 diluted with saline) in terms of time to peak enhancement (tPE) and peak enhancement (PE).
  
  
  RESULTS
  No significant differences were found between the standard and low-concentration test bolus in terms of tPE and PE.
  
  
  CONCLUSIONS
  A low-concentration test bolus (5 ml, 1:1 diluted with saline) is feasible in patients with a BMI ≤28 kg/m2.
authors.affiliation: University of Twente, MIRA-Institute for Biomedical Technology and Technical Medicine, Drienerlolaan 5, 7522 NB Enschede, The Netherlands; Department of Radiology, Jeroen Bosch Hospital, Henri Dunantstraat 1, 5223 GZ, 's-Hertogenbosch, The Netherlands. Electronic address: w.h.nijhof@gmail.com.
authors.forename: W H
authors.initials: WH
authors.lastname: Nijhof
authors.affiliation: University of Twente, MIRA-Institute for Biomedical Technology and Technical Medicine, Drienerlolaan 5, 7522 NB Enschede, The Netherlands.
authors.forename: M M
authors.initials: MM
authors.lastname: Jansen
authors.affiliation: Department of Radiology, Jeroen Bosch Hospital, Henri Dunantstraat 1, 5223 GZ, 's-Hertogenbosch, The Netherlands.
authors.forename: G J
authors.initials: GJ
authors.lastname: Jager
authors.affiliation: University of Twente, MIRA-Institute for Biomedical Technology and Technical Medicine, Drienerlolaan 5, 7522 NB Enschede, The Netherlands.
authors.forename: C H
authors.initials: CH
authors.lastname: Slump
authors.affiliation: Department of Radiology, Jeroen Bosch Hospital, Henri Dunantstraat 1, 5223 GZ, 's-Hertogenbosch, The Netherlands.
authors.forename: M J C M
authors.initials: MJ
authors.lastname: Rutten
mesh_terms: D001012:Aorta, Abdominal / Q000000981:diagnostic imaging*; D000072226:Computed Tomography Angiography / Q000379:methods*; D003287:Contrast Media / Q000008:administration & dosage*; D005240:Feasibility Studies; D006801:Humans; D061330:Multidetector Computed Tomography / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*; D015203:Reproducibility of Results; D014283:Triiodobenzoic Acids / Q000008:administration & dosage*
chemical_list: D003287:Contrast Media; D014283:Triiodobenzoic Acids; C054871:ioversol