title: Intravitreal bevacizumab role in the treatment of macular edema secondary to retinal vasoproliferative tumor in a patient with neurofibromatosis type 1.
abstract: Objective:To report a case of neurofibromatosis-1 (NF-1) with retinal vasoproliferative tumor (RVPT) and macular edema and exudation that was successfully treated with intravitreal bevacizumab (IVB).Method:A retrospective case report of patient with neurofibromatosis, retinal vasoproliferative tumor and macular edema who received three monthly intravitreal injections of bevacizumab. Optical coherence tomography (OCT) and fluorescein angiography (FAG) before and three months after treatment were done.Results:Macular edema and exudation of the right eye was effectively resolved with IVB injection and vascularity of RVPT significantly decreased after treatment with IVB.Conclusion:Macular edema and exudation secondary to RVPT in patients with NF-1 could be successfully treated with IVB.
authors.affiliation: Ophthalmic research center, Shahid Beheshti University of Medical Science, Tehran, Iran.
authors.forename: Ramin
authors.initials: R
authors.lastname: Nourinia
authors.affiliation: Ophthalmic research center, Shahid Beheshti University of Medical Science, Tehran, Iran.
authors.forename: Tahmineh
authors.initials: T
authors.lastname: Motevasseli
authors.affiliation: Ophthalmic research center, Shahid Beheshti University of Medical Science, Tehran, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Tofighi
keywords: intravitreal bevacizumab; macular edema; neurofibromatosis; vasoproliferative mass