title: Data describing inhibitory profiles of sugars against hemagglutination by the botulinum toxin complex ofClostridium botulinumserotypes C and D.
abstract: Serotype C and D ofClostridium botulinumproduce botulinum toxin complex (TC), which is comprised of botulinum neurotoxin, nontoxic nonhemagglutinin, and hemagglutinins (HAs). The TC is capable of aggregating equine erythrocytes via interaction between one of the HAs, namely HA-33, and sugar chains on the cell surface. This hemagglutination is inhibited by specific sugars. In this data article, we used four TCs from serotype C and D strains. The hemagglutination-inhibiting effects of 18 sugars and 8 glycoproteins were studied. The purified TC was mixed with the sugar to enable binding of the sugar to the TC; then, the erythrocytes were added to the mixture. Specific binding between the sugar and TC resulted in inhibition of cell aggregation. Here, data illustrating the inhibitory effects of various sugars and glycoproteins against hemagglutination induced by TC ofC. botulinumserotypes C and D are presented.
authors.affiliation: Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri 099-2493, Japan.
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Sagane
authors.affiliation: Groupwide Research and Development, Noevir Co., Ltd., 112-1, Okadacho, Higashiohmi 527-8588, Japan.
authors.forename: Minoru
authors.initials: M
authors.lastname: Ito
authors.affiliation: Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri 099-2493, Japan.
authors.forename: Keita
authors.initials: K
authors.lastname: Miyata
authors.affiliation: Department of Nutritional Science and Food Safety, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.
authors.forename: Tomonori
authors.initials: T
authors.lastname: Suzuki
authors.affiliation: Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri 099-2493, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Niwa
authors.affiliation: Department of Bioproduction, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri 099-2493, Japan.
authors.forename: Suguru
authors.initials: S
authors.lastname: Oguri
authors.affiliation: Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri 099-2493, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Watanabe
keywords: Botulinum toxin complex; Clostridium botulinum; Hemagglutinin; Sugar recognition