title: Clinical Development of Cell Therapies: Setting the Stage for Academic Success.
abstract: Cellular therapies have potential to treat a wide range of diseases with autologous immunotherapies showing unprecedented therapeutic promise in clinical trials. Such therapies are mainly developed by academic researchers applying small-scale production, targeting rare and unmet medical needs. Here, we highlight the clinical translation of immunotherapy product in an academic setting, which may serve as a success model for early academic development of cell-based therapeutics.
authors.affiliation: Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany.|Department of Nephrology and Internal Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Abou-El-Enein
authors.affiliation: Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany.|Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: H-D
authors.initials: HD
authors.lastname: Volk
authors.affiliation: Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany.|Department of Nephrology and Internal Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Reinke
mesh_terms: D000818:Animals; D064987:Cell- and Tissue-Based Therapy / Q000379:methods*; D002986:Clinical Trials as Topic; D006301:Health Services Needs and Demand; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D057170:Translational Research, Biomedical / Q000379:methods*