title: [Expert Meeting on COPD: Personalized Treatment of COPD - Wishful Thinking or Reality?]
abstract: Chronic obstructive pulmonary disease (COPD) is considered to be a complex and heterogeneous disease comprising multiple components. Its clinical presentation, pattern of functional disturbance, disease presentation and pathology varies tremendously between individuals despite the common feature of incompletely reversible airflow obstruction. It is therefore widely accepted that COPD is characterized by discriminable phenotypes that represent specific patterns of these disease features. COPD phenotypes are believed to correlate with outcome parameters such as severity of symptoms, exacerbations, functional loss or death and to require different treatment algorithms.This survey is the result of presentations that were given during an expert conference. It highlights the significance of major comorbidities, genetic, morphologic and inflammatory COPD-phenotypes and their impact on disease progression and treatment modalities.
authors.affiliation: Klinik für Pneumologie und Internistische Intensivmedizin, Klinikum Lüdenscheid.
authors.forename: J
authors.initials: J
authors.lastname: Lorenz
authors.affiliation: Pneumologie, Allergologie, Beatmungsmedizin, Universitätsklinikum des Saarlandes.
authors.forename: R
authors.initials: R
authors.lastname: Bals
authors.affiliation: Innere Medizin, Pneumologie, Internistische Intensivmedizin, Universitätsmedizin Greifswald.
authors.forename: R
authors.initials: R
authors.lastname: Ewert
authors.affiliation: Innere Medizin, Missionsärztliche Klinik Würzburg.
authors.forename: B
authors.initials: B
authors.lastname: Jany
authors.affiliation: Klinik für Innere Medizin, Schwerpunkt Pneumologie, Universitätsklinikum Marburg.
authors.forename: A R
authors.initials: AR
authors.lastname: Koczulla
authors.affiliation: Klinik für Pneumologie und Intensivmedizin, Klinikum St. Georg, Leipzig.
authors.forename: T
authors.initials: T
authors.lastname: Köhnlein
authors.affiliation: Klinik für Pneumologie und Allergologie, Krankenhaus Bethanien, Solingen.
authors.forename: W J
authors.initials: WJ
authors.lastname: Randerath
authors.affiliation: Medizinisch-wissenschaftliches Publizieren, Schwerin.
authors.forename: G
authors.initials: G
authors.lastname: Steinkamp
authors.affiliation: Pneumologisches Forschungsinstitut an der LungenClinic Großhansdorf.
authors.forename: H
authors.initials: H
authors.lastname: Watz
authors.affiliation: Klinik für Pneumologie, Medizinische Hochschule Hannover.
authors.forename: T
authors.initials: T
authors.lastname: Welte
mesh_terms: D003226:Congresses as Topic; D005104:Expert Testimony; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005858:Germany; D058990:Molecular Targeted Therapy / Q000379:methods*; D057285:Precision Medicine / Q000379:methods*; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy*