title: Oesophageal carcinoma: comparison of ex vivo high-resolution 3.0 T MR imaging with histopathological findings.
abstract: High-resolution magnetic resonance (MR) images clearly depict the normal oesophageal wall as consisting of eight layers, which correlates well with histopathological findings. In 56 (91.8%) of 61 lesions, the depth of oesophageal wall invasion determined through MR imaging was consistent with histopathological staging (r = 0.975, P < 0.001). The sensitivity, specificity and accuracy for the mucosa were 71.4%, 98.1%, and 95.1%, respectively, and the corresponding values for the submucosa were 82.4%, 95.5%, and 91.8%; for the muscularis propria, the sensitivity, specificity and accuracy were 100%, 95.7%, and 96.7%, respectively, and for the adventitia, these values were 100%, 100%, and 100%. The Cohen k values for interobserver agreement were excellent: K = 0.839, P < 0.001 (observer 1 vs. observer 2); K = 0.908, P < 0.001 (observer 1 vs. observer 3); and K = 0.885, P < 0.01 (observer 2 vs. observer 3). High-resolution ex vivo MR images obtained with a 3.0 T scanner can be used to precisely evaluate oesophageal carcinoma invasion and provide good diagnostic sensitivity, specificity and accuracy.
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Center of Thoracic Tumor, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Center of Thoracic Tumor, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Sen
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Dapeng
authors.initials: D
authors.lastname: Shi
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Shewei
authors.initials: S
authors.lastname: Dou
authors.affiliation: Department of Pathology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Pathology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Tingyi
authors.initials: T
authors.lastname: Sun
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Peigang
authors.initials: P
authors.lastname: Ning
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Cuihua
authors.initials: C
authors.lastname: Zhao
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Ziyuan
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Feifei
authors.initials: F
authors.lastname: Gao
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Linlin
authors.initials: L
authors.lastname: Li
authors.affiliation: GE Healthcare China, Beijing 100176, China.
authors.forename: Dandan
authors.initials: D
authors.lastname: Zheng
authors.affiliation: Department of Radiology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.|Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China.
authors.forename: Shaocheng
authors.initials: S
authors.lastname: Zhu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D009092:Mucous Membrane / Q000473:pathology; D012680:Sensitivity and Specificity