title: Stability research on polydopamine and immobilized albumin on 316L stainless steel.
abstract: In this study, the polydopamine (PDA) film was coated on polished 316Lss and then thermally treated at 150 °C (labeled as PDA-Th150), and the stability of coatings was also investigated. Straining test indicated that PDA-Th150 coating performed better in affording sufficient adherence to 316 L SS substrate. Moreover, both PDA and PDA-Th150 coating suffered slight swelling during immersion in deionized water (pH = 6.5). X-ray photoelectron spectroscopy results showed that during immersion, latent nucleophilic reaction via amines inside PDA coating occurred. This led to an enhanced cross-linking and thus gradually promoted the coating stability. Moreover, larger amount of bovine serum albumin (BSA) was immobilized onto PDA-Th150 coating and performed well in anti-platelet adhesion. A high retention of immobilized BSA was observed even after immersion for 30 days. These tests suggested that PDA was stable enough and performed well in surface functionalization, which might enrich the research and application of PDA.
authors.affiliation: School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.affiliation: School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
authors.forename: Lingxia
authors.initials: L
authors.lastname: Xie
authors.affiliation: School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
authors.forename: Jinchuan
authors.initials: J
authors.lastname: Deng
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
authors.forename: Weihua
authors.initials: W
authors.lastname: Zhuang
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
authors.forename: Rifang
authors.initials: R
authors.lastname: Luo
authors.affiliation: School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
authors.affiliation: School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Huang
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
authors.forename: Yunbing
authors.initials: Y
authors.lastname: Wang
keywords: X-ray photoelectron spectroscopy (XPS); catechol; polydopamine; stability; thermal