title: Current and emerging therapies in premature ejaculation: Where we are coming from, where we are going.
abstract: Premature ejaculation is the most common form of sexual dysfunction among men. The pathophysiology of premature ejaculation appears to be multifactorial, implicating the need for multimodal therapeutic regimens to successfully treat premature ejaculation. Multiple treatment regimens have been shown to be effective in extending the time between penetration and ejaculation. These treatment modalities include everything from behavioral modifications and medications to diet alterations and major surgery. The goal of the present article was to review the commonly used treatment regimens used in the treatment of premature ejaculation, as well as to introduce and discuss the newest treatment routines under study for the treatment of premature ejaculation.
authors.affiliation: Department of Urology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Martin
authors.affiliation: Department of Urology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
authors.forename: Hunter
authors.initials: H
authors.lastname: Nolen
authors.affiliation: Department of Urology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Podolnick
authors.affiliation: Department of Urology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
authors.forename: Run
authors.initials: R
authors.lastname: Wang
mesh_terms: D026881:Acupuncture / Q000379:methods; D000779:Anesthetics, Local / Q000008:administration & dosage; D000818:Animals; D001521:Behavior Therapy / Q000379:methods*; D002944:Circumcision, Male; D004195:Disease Models, Animal; D004542:Ejaculation / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D010413:Penis / Q000187:drug effects / Q000294:innervation / Q000601:surgery*; D058986:Phosphodiesterase 5 Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D061686:Premature Ejaculation / Q000209:etiology / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D017367:Selective Serotonin Reuptake Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D000068760:Serotonin and Noradrenaline Reuptake Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D016896:Treatment Outcome; D014646:Varicocele / Q000150:complications / Q000601:surgery*; D015013:Yoga
chemical_list: D000779:Anesthetics, Local; D058986:Phosphodiesterase 5 Inhibitors; D010936:Plant Extracts; D017367:Selective Serotonin Reuptake Inhibitors; D000068760:Serotonin and Noradrenaline Reuptake Inhibitors
keywords: ejaculation; premature; therapy; treatment