title: [SICI-GISE Position paper: Use of Absorb BVS in clinical practice].
abstract: Drug-eluting stents (DES) are the current gold standard for percutaneous treatment of coronary artery disease. However, DES are associated with a non-negligible risk of long-term adverse events related to persistence of foreign material in the coronary artery wall. In addition, DES implantation causes permanent caging of the native vessel, thus impairing normal vasomotricity and the possibility of using non-invasive coronary imaging or preforming subsequent bypass surgery. On the contrary, coronary bioresorbable stents (BRS) may provide temporary mechanical support to coronary wall without compromising the subsequent recovery of normal vascular physiology, and have the potential to prevent late adverse events related to permanent elements. Several types of BRS have been introduced into clinical practice in Europe or are being tested. However, most of available clinical data relate to a single BRS, the Absorb bioresorbable Vascular Scaffold (Absorb BVS) (Abbott Vascular, Santa Clara, CA). Despite encouraging clinical results, no societal guidelines are available on the use of BRS in clinical practice.A panel of Italian expert cardiologists assembled under the auspices of the Italian Society of Interventional Cardiology (SICI-GISE) for comprehensive discussion and consensus development, with the aim to provide recommendations on the use of bioresorbable stents in terms of clinical indications, procedural aspects, post-percutaneous coronary angioplasty pharmacologic treatment and follow-up. Based on current evidence and BRS availability in Italian cath-labs, the panel decided unanimously to provide specific recommendations for the Absorb BVS device. These recommendations do not necessarily extend to other BRS, unless specified, although significant overlap may exist with Absorb BVS, particularly in terms of clinical rationale.
authors.affiliation: Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari, Policlinico Universitario, Padova.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Tarantini
authors.affiliation: Dipartimento Cardio-Toraco-Vascolare, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna.
authors.forename: Francesco
authors.initials: F
authors.lastname: Saia
authors.affiliation: Dipartimento Cardiovascolare, Ospedale Ferrarotto, Università degli Studi, Catania.
authors.forename: Piera
authors.initials: P
authors.lastname: Capranzano
authors.affiliation: Cardiologia Interventistica, A.O. Fatebenefratelli, Milano.
authors.forename: Bernardo
authors.initials: B
authors.lastname: Cortese
authors.affiliation: Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari, Policlinico Universitario, Padova.
authors.forename: Marco
authors.initials: M
authors.lastname: Mojoli
authors.affiliation: Cardiologia Interventistica, Azienda Sanitaria Locale Torino 2, Torino.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Boccuzzi
authors.affiliation: Dipartimento di Cardiologia, A.O. Ospedali Riuniti, Foggia.
authors.forename: Andrea
authors.initials: A
authors.lastname: Cuculo
authors.affiliation: Cardiologia Interventistica, Ospedale S. Giovanni di Dio, Agrigento.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Geraci
authors.affiliation: Cardiologia Interventistica, Ospedale Moriggia Pelascini, Gravedona (CO).
authors.forename: Alessio
authors.initials: A
authors.lastname: Mattesini
authors.affiliation: Emodinamica, ASST Grande Ospedale Metropolitano Niguarda, Milano.
authors.forename: Jacopo
authors.initials: J
authors.lastname: Oreglia
authors.affiliation: Dipartimento di Cardiologia, Policlinico Casilino, Roma.
authors.forename: Francesco
authors.initials: F
authors.lastname: Summaria
authors.affiliation: Dipartimento di Cardiologia, IRCCS Policlinico S. Donato, S. Donato Milanese (MI).
authors.forename: Luca
authors.initials: L
authors.lastname: Testa
authors.affiliation: U.O. Cardiologia Diagnostica ed Interventistica, Fondazione Toscana "Gabriele Monasterio", Ospedale del Cuore, Massa.
authors.forename: Sergio
authors.initials: S
authors.lastname: Berti
authors.affiliation: Dipartimento di Scienze Biomediche Avanzate, Università degli Studi "Federico II", Napoli.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Esposito
authors.affiliation: Dipartimento Cardiovascolare, Ospedale Ferrarotto, Università degli Studi, Catania.
authors.forename: Alessio
authors.initials: A
authors.lastname: La Manna
authors.affiliation: U.O.C. Cardiologia, Azienda USL Toscana Sudest, Grosseto.
authors.forename: Ugo
authors.initials: U
authors.lastname: Limbruno
authors.affiliation: U.O.C. Cardiologia Interventistica, Anthea Hospital, GVM Care & Research, Bari.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Marchese
authors.affiliation: Dipartimento Cardiovascolare, Ospedale Cardarelli, Napoli.
authors.forename: Ciro
authors.initials: C
authors.lastname: Mauro
authors.affiliation: Laboratorio di Emodinamica, U.O. Cardiologia, Ospedale G.B. Morgagni-L. Pierantoni, Forlì.
authors.forename: Fabio
authors.initials: F
authors.lastname: Tarantino
authors.affiliation: Dipartimento Cardiovascolare, Ospedali Riuniti, Università degli Studi, Trieste.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Salvi
authors.affiliation: Cardiologia Interventistica, AOU Careggi, Firenze.
authors.forename: Gennaro
authors.initials: G
authors.lastname: Santoro
authors.affiliation: Dipartimento di Cardiologia, Ospedale degli Infermi, Rivoli (TO).
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Varbella
authors.affiliation: Cardiologia Interventistica, Ospedale S. Camillo-Forlanini, Roma.
authors.forename: Roberto
authors.initials: R
authors.lastname: Violini
authors.affiliation: Dipartimento Cardiovascolare, ASST Papa Giovanni XXIII, Bergamo.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Musumeci
mesh_terms: D020341:Absorbable Implants; D002309:Cardiology; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D003324:Coronary Artery Disease / Q000628:therapy*; D054855:Drug-Eluting Stents; D006801:Humans; D007558:Italy; D062645:Percutaneous Coronary Intervention; D018570:Risk Assessment; D012307:Risk Factors; D012955:Societies, Medical; D013997:Time Factors; D054457:Tissue Scaffolds
chemical_list: D002317:Cardiovascular Agents