title: Efficient and selective N-alkylation of amines with alcohols catalysed by manganese pincer complexes.
abstract: Borrowing hydrogen (or hydrogen autotransfer) reactions represent straightforward and sustainable C-N bond-forming processes. In general, precious metal-based catalysts are employed for this effective transformation. In recent years, the use of earth abundant and cheap non-noble metal catalysts for this process attracted considerable attention in the scientific community. Here we show that the selective N-alkylation of amines with alcohols can be catalysed by defined PNP manganese pincer complexes. A variety of substituted anilines are monoalkylated with different (hetero)aromatic and aliphatic alcohols even in the presence of other sensitive reducible functional groups. As a special highlight, we report the chemoselective monomethylation of primary amines using methanol under mild conditions.
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, Rostock 18059, Germany.|UMR 6226 CNRS-Université de Rennes 1 Institut des Sciences Chimiques de Rennes, Team Organometallics: Materials and Catalysis-Centre for Catalysis and Green Chemistry, campus de Beaulieu, 35042 Rennes, France.
authors.forename: Saravanakumar
authors.initials: S
authors.lastname: Elangovan
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, Rostock 18059, Germany.
authors.forename: Jacob
authors.initials: J
authors.lastname: Neumann
authors.affiliation: UMR 6226 CNRS-Université de Rennes 1 Institut des Sciences Chimiques de Rennes, Team Organometallics: Materials and Catalysis-Centre for Catalysis and Green Chemistry, campus de Beaulieu, 35042 Rennes, France.
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Sortais
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, Rostock 18059, Germany.
authors.forename: Kathrin
authors.initials: K
authors.lastname: Junge
authors.affiliation: UMR 6226 CNRS-Université de Rennes 1 Institut des Sciences Chimiques de Rennes, Team Organometallics: Materials and Catalysis-Centre for Catalysis and Green Chemistry, campus de Beaulieu, 35042 Rennes, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Darcel
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, Rostock 18059, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller