title: Short-term exposure to ambient fine particulate matter (PM2,5 and PM10) and the risk of heart rhythm abnormalities and stroke.
abstract: Results of epidemiological studies suggest a significant impact of ambient particulate matter air pollution (PM10 and PM2,5) on the health of the population. Increased level of these pollutants is connected with increased rate of daily mortality and hospitalizations due to cardiovascular diseases. Among analyzed health effects, heart arrhythmias and stroke are mentioned most frequently. The aim of the study was to present the current knowledge of potential influence of the exposure to fine particulate matter on the presence of arrhythmias and strokes. Subject literature review suggests, that there is a link between short-term exposure to fine dust and the occurrence of arrhythmias. Results of previous studies indicates that this exposure may lead to significant electrophysiological changes in heart, resulting in higher susceptibility to cardiac rhythm abnormalities. In case of stroke, a stronger correlation between number of hospitalizations and death cases and exposure to fine dust was seen for ischaemic stroke than for haemorhhagic stroke. In addition, a significantly more harmful impact of the exposure to ultra particles (particles of aerodynamic diameter below 2,5 μm) has been confirmed. Among important mechanisms responsible for observed health impact of particulate matter there are: induction and intensification of inflammation, increased oxidative stress, increased autonomic nervous system activity, vasoconstriction, rheological changes and endothelial dysfunction. Among people of higher susceptibility to fine dust negative health impact are: elderly (over 65 years old), obese people, patients with respiratory and cardiovascular diseases, patients with diabetes and those with coagulation disorders. For further improvement of general health status, actions aimed at reducing the risk associated with fine dust and at the same time at continuing studies to clarify the biological mechanisms explaining the influence of fine dust on human health are necessary.
authors.affiliation: Katedra i Zakład Epidemiologii, Wydział Lekarski w Katowicach, Śląski Uniwersytet Medyczny.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Kowalska
authors.affiliation: Koło Naukowe przy Katedrze i Zakładzie Epidemiologii, Wydział Lekarski w Katowicach, Śląski Uniwersytet Medyczny.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Kocot
mesh_terms: D000367:Age Factors; D000393:Air Pollutants / Q000009:adverse effects* / Q000633:toxicity; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D052638:Particulate Matter / Q000009:adverse effects* / Q000633:toxicity; D012307:Risk Factors; D020521:Stroke / Q000139:chemically induced* / Q000453:epidemiology; D013997:Time Factors
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter