title: EEG-fMRI Study of Alpha-Stimulation Neurobiofeedback Training Course.
abstract: fMRI-EEG dynamics of brain activity in volunteers was studied during the course of EEG alpha-stimulation training (20 sessions). Twenty-three healthy men (20-35 years) were subjected to 3-fold mapping in a feedback loop (EEG alpha-rhythm biofeedback with acoustic reinforcement). This procedure was performed at the beginning, middle, and end of the course. During the first neurofeedback training session, deactivation (p<0.001) was found in the right angular gyrus, supramarginal, and superior temporal gyri, Brodmann area 39, and cerebellum. Activation (p<0.001) was observed in the medial frontal and cingulate gyri, motor areas of both hemispheres, and Brodmann area 32. During final (third) neurofeedback training session, we observed strong deactivation (p<0.05 with FDR) of zones responsible for spatial thinking and motor functions: left medial frontal and left medial temporal gyri; right postcentral, lingual, and superior frontal gyri; insula and right side of the cerebellum; and precuneus and cuneus (Brodmann areas 6, 9, 7, 31, 8, 13, and 22). Changes in the alpha wave power were most pronounced in the primary and secondary somatosensory cortex of the left hemisphere (Brodmann areas 2L and 5L).
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Novosibirsk, Russia. luydmilakozlova@yandex.ru.|Novosibirsk State University, Novosibirsk, Russia. luydmilakozlova@yandex.ru.
authors.forename: L I
authors.initials: LI
authors.lastname: Kozlova
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Novosibirsk, Russia.|Novosibirsk State University, Novosibirsk, Russia.
authors.forename: M B
authors.initials: MB
authors.lastname: Shtark
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Novosibirsk, Russia.|Novosibirsk State University, Novosibirsk, Russia.
authors.forename: M E
authors.initials: ME
authors.lastname: Mel'nikov
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Novosibirsk, Russia.
authors.forename: E G
authors.initials: EG
authors.lastname: Verevkin
authors.affiliation: International Tomography Center, Novosibirsk, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Savelov
authors.affiliation: International Tomography Center, Novosibirsk, Russia.
authors.forename: E D
authors.initials: ED
authors.lastname: Petrovskii
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D000513:Alpha Rhythm; D001931:Brain Mapping; D004569:Electroencephalography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D058765:Neurofeedback; D009778:Occipital Lobe / Q000502:physiology*; D013003:Somatosensory Cortex / Q000502:physiology*; D013702:Temporal Lobe / Q000502:physiology*; D055815:Young Adult
keywords: EEG-fMRI mapping; alpha waves; alpha-stimulation training; biofeedback