title: [Anti-thymocyte Globulin Therapy for Cases of Acute Rejection Following Lung Transplantation].
abstract: A 58-year-old male underwent right lung transplantation from a brain-dead donor, after which acute rejection developed that was resistant to steroid pulse therapy. Rabbit-derived anti-thymocyte globulin (rATG) therapy was successful for controlling the rejection. However, following that therapy, the patient was affected by an opportunistic infection and suffered from repeated empyema. It is important to pay attention to immunosuppressive agent levels in blood following treatment, because ATG is a potent immunosuppressive drug and its effects can continue for more than 6 months after administration.
authors.affiliation: Department of General Thoracic Surgery, Dokkyo Medical University, Tochigi, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Karube
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ito
authors.forename: Morimichi
authors.initials: M
authors.lastname: Nishihira
authors.forename: Takashi
authors.initials: T
authors.lastname: Inoue
authors.forename: Osamu
authors.initials: O
authors.lastname: Araki
authors.forename: Sumiko
authors.initials: S
authors.lastname: Maeda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Chida
mesh_terms: D000208:Acute Disease; D000818:Animals; D000961:Antilymphocyte Serum / Q000627:therapeutic use*; D006084:Graft Rejection / Q000276:immunology*; D006801:Humans; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D011817:Rabbits; D060168:Thymocytes / Q000276:immunology*; D014057:Tomography, X-Ray Computed
chemical_list: D000961:Antilymphocyte Serum