title: Cytomegalovirus.
abstract: Cytomegalovirus (CMV), the largest of the herpesviruses, causes a wide range of clinical syndromes, from asymptomatic infection to severe disease in immunocompromised hosts. Laboratory methods for diagnosis include molecular testing, antigenemia, culture, serology, and histopathology. Treatment of CMV infection and disease is indicated in selected immunocompromised hosts, and preventive approaches are indicated in high-risk groups. This chapter reviews the epidemiology, clinical aspects, and the laboratory diagnosis and management of CMV in immunocompromised hosts.
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: M Veronica
authors.initials: MV
authors.lastname: Dioverti
authors.affiliation: Division of Infectious Diseases, Department of Medicine.|The William J von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic College of Medicine, Rochester, MN 55905.
authors.forename: Raymund R
authors.initials: RR
authors.lastname: Razonable
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D019411:Clinical Laboratory Techniques / Q000379:methods*; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology*; D003955:Diagnostic Tests, Routine / Q000379:methods*; D004198:Disease Susceptibility; D006801:Humans; D016867:Immunocompromised Host
chemical_list: D000998:Antiviral Agents