title: Short-term Outcomes of Induced Membrane Technique in Treatment of Long Bone Defects in Iran.
abstract: BACKGROUND
  Severe defects in long bones can be caused by several factors such as trauma that lead to open wound and secondary infections after surgery. Induced membrane technique is one of the therapeutic strategies that can be used for these patients. Due to importance of this method and lack of information about this technique in Iran.
  
  
  OBJECTIVE
  this study was performed to investigate technical strengths and weakness of induced membrane technique.
  
  
  METHODS
  This case series study conducted on 21 patients with bone defects in the femur and tibia and metatarsal bones referred to orthopedic clinic of Rasoul Akram Hospital, Tehran, Iran, for induced membrane surgery in 2012-2015. Demographic and clinical data were obtained using history, clinical examinations and observations for each patient. Union achievement was the main outcome of this study, which was confirmed by radiographic findings and physical examination. Obtained data was analyzed by SPSS ver. 16.
  
  
  RESULTS
  All patients were male except one and their mean age was 30.52 years old. Bone defects were in tibia, femur and metatarsus in 9, 9 and 3 patients, respectively. Three patients received soft tissue reconstruction with flap before induced membrane surgery. Age, defects size, cigarette addiction and drug use and delay to start the treatment had no significant effect on union status. In total, 90% of patients had successful surgery.
  
  
  CONCLUSIONS
  using induced membrane technique in patients with defects in their long bone such as tibia, femur and metatarsus would lead to high success for reconstruction.
authors.affiliation: Department of Orthopedics, Rasool-e-akram Hospital, Iran University of Medical Science, Tehran, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Yeganeh
authors.affiliation: Department of Orthopedics, Rasool-e-akram Hospital, Iran University of Medical Science, Tehran, Iran.
authors.forename: Mani
authors.initials: M
authors.lastname: Mahmodi
authors.affiliation: Department of Orthopedics, Rasool-e-akram Hospital, Iran University of Medical Science, Tehran, Iran.
authors.forename: Hosein
authors.initials: H
authors.lastname: Farahini
authors.affiliation: Department of Orthopedics, Rasool-e-akram Hospital, Iran University of Medical Science, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Moghtadaei
mesh_terms: D000328:Adult; D000368:Aged; D001843:Bone Cements / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods*; D003646:Debridement; D005260:Female; D005269:Femur; D006801:Humans; D007492:Iran; D008297:Male; D008682:Metatarsal Bones; D008875:Middle Aged; D009984:Orthopedic Fixation Devices; D019637:Orthopedic Procedures / Q000379:methods*; D010019:Osteomyelitis / Q000601:surgery*; D019904:Polymethyl Methacrylate / Q000008:administration & dosage / Q000627:therapeutic use; D019651:Plastic Surgery Procedures; D013524:Surgical Flaps; D013977:Tibia; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate
keywords: femur; induced membrane technique; metatarsus; tibia; union