title: The Movement Tracker: A Flexible System for Automated Movement Analysis in Invertebrate Model Organisms.
abstract: Phenotyping strategies in simple model organisms such as D. melanogaster and C. elegans are often broadly limited to growth, aging, and fitness. Recently, a number of physical setups and video tracking software suites have been developed to allow for accurate, quantitative, and high-throughput analysis of movement in flies and worms. However, many of these systems require precise experimental setups and/or fixed recording formats. We report here an update to the Parallel Worm Tracker software, which we termed the Movement Tracker. The Movement Tracker allows variable experimental setups to provide cross-platform automated processing of a variety of movement characteristics in both worms and flies and permits the use of simple physical setups that can be readily implemented in any laboratory. This software allows high-throughput processing capabilities and high levels of flexibility in video analysis, providing quantitative movement data on C. elegans and D. melanogaster in a variety of different conditions. © 2016 by John Wiley & Sons, Inc.
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Laurent
authors.initials: L
authors.lastname: Mouchiroud
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Sorrentino
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Evan G
authors.initials: EG
authors.lastname: Williams
authors.affiliation: Laboratory of Microsystems, École Polytechnique Fédérale de Lausanne, Switzerland, Lausanne, Switzerland.
authors.forename: Matteo
authors.initials: M
authors.lastname: Cornaglia
authors.affiliation: Laboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, Switzerland, Lausanne, Switzerland.
authors.forename: Michael V
authors.initials: MV
authors.lastname: Frochaux
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Tao
authors.initials: T
authors.lastname: Lin
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Amandine A
authors.initials: AA
authors.lastname: Nicolet-Dit-Félix
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Gopal
authors.initials: G
authors.lastname: Krishnamani
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Tarik
authors.initials: T
authors.lastname: Ouhmad
authors.affiliation: Laboratory of Microsystems, École Polytechnique Fédérale de Lausanne, Switzerland, Lausanne, Switzerland.
authors.forename: Martin A M
authors.initials: MAM
authors.lastname: Gijs
authors.affiliation: Laboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, Switzerland, Lausanne, Switzerland.
authors.forename: Bart
authors.initials: B
authors.lastname: Deplancke
authors.affiliation: Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Johan
authors.initials: J
authors.lastname: Auwerx
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D017173:Caenorhabditis elegans / Q000378:metabolism; D004331:Drosophila melanogaster / Q000378:metabolism; D008124:Locomotion / Q000502:physiology; D023421:Models, Animal; D012984:Software; D013223:Statistics as Topic / Q000295:instrumentation
keywords: C. elegans; D. melanogaster; aging; model organisms; movement; neurodegeneration; software