title: Postoperative time dependent tibiofemoral articular cartilage contact kinematics during step-up after ACL reconstruction.
abstract: This study was to investigate the in vivo tibiofemoral cartilage contact locations before and after anterior cruciate ligament (ACL) reconstruction at 6 and 36 months. Ten patients with unilateral ACL injury were included. A step-up motion was analyzed using a combined magnetic resonance modeling and dual fluoroscopic imaging techniques. The preoperative (i.e. ACL deficient and healthy contralateral) and postoperative cartilage contact locations at 6 and 36 months were analyzed. Similar patterns of the cartilage contact locations during the step-up motion were found for the preoperative and postoperative knee states as compared to the preoperative healthy contralateral side. At the end of step-up motion, the medial contact locations at postoperative 36 months were more anterior when compared to the preoperative healthy contralateral (p=0.02) and 6 months postoperative knee states (p=0.01). The changes of the cartilage contact locations at 36 months after ACL reconstruction compared to the healthy contralateral side were strongly correlated with the changes at 6 months postoperatively. This study showed that the tibiofemoral cartilage contact locations of the knee changes with time after ACL reconstruction, implying an ongoing recovery process within the 36 months after the surgery. There could be an association between the short-term (6 months) and longer-term (36 months) contact kinematics after ACL reconstruction. Future studies need to investigate the intrinsic relationship between knee kinematics at different times after ACL reconstruction.
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States; Institute of Sports Medicine, Peking University Third hospital, North Garden Road, Haidian District, Beijing 100191, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Lin
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States.
authors.forename: Jing-Sheng
authors.initials: JS
authors.lastname: Li
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States.
authors.forename: Willem A
authors.initials: WA
authors.lastname: Kernkamp
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States.
authors.forename: Ali
authors.initials: A
authors.lastname: Hosseini
authors.affiliation: Department of Orthopedic Surgery, Busan Paik Hospital, College of Medicine, Inje University, 633-166 Gaegeum-dong, Busan Jin-gu, Busan 614-735, South Korea.
authors.forename: ChangWan
authors.initials: C
authors.lastname: Kim
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States; Department of Orthopaedics, Chinese PLA General Hospital, No. 28 Fuxin Road, Beijing 100853, China; Medical College, Nankai University, No. 94 Weijin Road, Tianjin 300071, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Yin
authors.affiliation: Department of Orthopedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
authors.forename: Lianxin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States.
authors.forename: Tsung-Yuan
authors.initials: TY
authors.lastname: Tsai
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States.
authors.forename: Peter
authors.initials: P
authors.lastname: Asnis
authors.affiliation: Bioengineering laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States. Electronic address: gli1@partners.org.
authors.forename: Guoan
authors.initials: G
authors.lastname: Li
mesh_terms: D000328:Adult; D016118:Anterior Cruciate Ligament / Q000473:pathology / Q000601:surgery; D000070598:Anterior Cruciate Ligament Injuries / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D059549:Anterior Cruciate Ligament Reconstruction; D001696:Biomechanical Phenomena; D002358:Cartilage, Articular / Q000473:pathology; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D000072799:Stair Climbing; D016896:Treatment Outcome; D055815:Young Adult
keywords: Anterior cruciate ligament reconstruction; Biomechanics; Cartilage contact; Osteoarthritis