title: Human Split-Thickness Skin Allograft from Brain-Dead Donors.
abstract: BACKGROUND
  Looking for an appropriate skin substitute for temporary and permanent coverage of wounds remains one of the main obstacles of medical researchers.
  
  
  OBJECTIVE
  To investigate the rate of inflammation, symbiosis, and survival of grafted allograft skin from brain-dead donors (BDDs) in rabbits.
  
  
  METHODS
  After receiving negative serologic tests of BDDs, we prepared partial thickness skin grafts. They were then used in treating wounds of 5 rabbits in comparison with split-thickness skins taken from cardiac dead donors.
  
  
  RESULTS
  On histopathological examinations, we found no difference between the skins. All samples were separated from the baseline in 15-20 days.
  
  
  CONCLUSIONS
  Gamma-irradiated freeze-dried human split-thickness skin taken from BDDs is safe and can be used for the treatment of deep skin burns.
authors.affiliation: Iranian Tissue Bank Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Khodadadi
authors.affiliation: Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: O
authors.initials: O
authors.lastname: Olang
authors.affiliation: Molecular and Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Makhllough
authors.affiliation: Iranian Tissue Bank Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: B
authors.initials: B
authors.lastname: Nozary Heshmati
authors.affiliation: Iranian Tissue Bank Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: F
authors.initials: F
authors.lastname: Azmoudeh Ardalan
authors.affiliation: Iranian Tissue Bank Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: S A
authors.initials: SA
authors.lastname: Tavakoli
keywords: Biological dressings; Graft; Graft rejection; Inflammation; Survival; Symbiosis