title: Do CAD/CAM dentures really release less monomer than conventional dentures?
abstract: OBJECTIVE
  Computer-aided design (CAD)/computer-aided manufacturing (CAM) dentures are assumed to have more favourable material properties than conventionally fabricated dentures, among them a lower methacrylate monomer release. The aim of this study was to test this hypothesis.
  
  
  METHODS
  CAD/CAM dentures were generated from ten different master casts by using four different CAD/CAM systems. Conventional, heat-polymerised dentures served as control group. Denture weight and volume were measured; the density was calculated, and the denture surface area was assessed digitally. The monomer release after 7 days of water storage was measured by high-performance liquid chromatography.
  
  
  RESULTS
  Whole You Nexteeth and Wieland Digital Dentures had significantly lower mean volume and weight than conventional dentures. Baltic Denture System and Whole You Nexteeth had a significantly increased density. Baltic Denture System had a significantly smaller surface area. None of the CAD/CAM dentures released significantly less monomer than the control group.
  
  
  CONCLUSIONS
  All tested dentures released very low amounts of methacrylate monomer, but not significantly less than conventional dentures. A statistically significant difference might nevertheless exist in comparison to other, less recommendable denture base materials, such as the frequently used autopolymerising resins.
  
  
  CONCLUSIONS
  CAD/CAM denture fabrication has numerous advantages. It enables the fabrication of dentures with lower resin volume and lower denture weight. Both could increase the patient comfort. Dentures with higher density might exhibit more favourable mechanical properties. The hypothesis that CAD/CAM dentures release less monomer than conventional dentures could, however, not be verified.
authors.affiliation: University Hospital for Dental Prosthetics and Restorative Dentistry, Medical University of Innsbruck, MZA, Anichstr. 35, A-6020, Innsbruck, Austria.
authors.forename: Patricia-Anca
authors.initials: PA
authors.lastname: Steinmassl
authors.affiliation: Institute of Analytical Chemistry and Radiochemistry, University of Innsbruck, CCB, Innrain 80, A-6020, Innsbruck, Austria.
authors.forename: Verena
authors.initials: V
authors.lastname: Wiedemair
authors.affiliation: Institute of Analytical Chemistry and Radiochemistry, University of Innsbruck, CCB, Innrain 80, A-6020, Innsbruck, Austria.
authors.forename: Christian
authors.initials: C
authors.lastname: Huck
authors.affiliation: University Hospital for Dental Prosthetics and Restorative Dentistry, Medical University of Innsbruck, MZA, Anichstr. 35, A-6020, Innsbruck, Austria.
authors.forename: Florian
authors.initials: F
authors.lastname: Klaunzer
authors.affiliation: University Hospital for Cranio-Maxillofacial and Oral Surgery, Medical University of Innsbruck, MZA, Anichstr. 35, A-6020, Innsbruck, Austria. otto.steinmassl@i-med.ac.at.
authors.forename: Otto
authors.initials: O
authors.lastname: Steinmassl
authors.affiliation: University Hospital for Dental Prosthetics and Restorative Dentistry, Medical University of Innsbruck, MZA, Anichstr. 35, A-6020, Innsbruck, Austria.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Grunert
authors.affiliation: University Hospital for Dental Prosthetics and Restorative Dentistry, Medical University of Innsbruck, MZA, Anichstr. 35, A-6020, Innsbruck, Austria.
authors.forename: Herbert
authors.initials: H
authors.lastname: Dumfahrt
mesh_terms: D002851:Chromatography, High Pressure Liquid; D017076:Computer-Aided Design; D003764:Dental Materials / Q000737:chemistry*; D003779:Denture Design; D008422:Materials Testing; D020366:Methylmethacrylate / Q000737:chemistry*
chemical_list: D003764:Dental Materials; D020366:Methylmethacrylate
keywords: CAD/CAM dentistry; Complete dentures; Monomer release; PMMA