title: Research progress of long noncoding RNA in China.
abstract: RNA is essential for all kingdoms of life and exerts important functions beyond transferring genetic information from DNA to protein. With the advent of the state-of-the-art deep sequencing technology, a large portion of noncoding transcripts in eukaryotic genomes has been broadly identified. Among them, long noncoding RNAs (lncRNAs) have been emerged as a new class of RNA molecules that have regulatory potential in a variety of physiological and pathological processes. Here we summarize recent research progresses that have been made by scientists in China on lncRNAs, including their biogenesis, functional implication and the underlying mechanism of action at the current stage. © 2016 IUBMB Life, 68(11):887-893, 2016.
authors.affiliation: State Key Laboratory of Molecular Biology, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.|University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Yu-Hang
authors.initials: YH
authors.lastname: Xing
authors.affiliation: State Key Laboratory of Molecular Biology, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Bai
authors.affiliation: State Key Laboratory of Molecular Biology, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.|University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Chu-Xiao
authors.initials: CX
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Molecular Biology, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.|University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Shi-Bin
authors.initials: SB
authors.lastname: Hu
authors.affiliation: Shanghai Information Center for Life Sciences, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Meihua
authors.initials: M
authors.lastname: Ruan
authors.affiliation: State Key Laboratory of Molecular Biology, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China. linglingchen@sibcb.ac.cn.|School of Life Science, ShanghaiTech University, Shanghai, China. linglingchen@sibcb.ac.cn.|University of Chinese Academy of Sciences, Beijing, China. linglingchen@sibcb.ac.cn.
authors.forename: Ling-Ling
authors.initials: LL
authors.lastname: Chen
mesh_terms: D000818:Animals; D015706:Bibliometrics; D035843:Biomedical Research / Q000592:standards*; D063646:Carcinogenesis / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D002681:China; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D058996:Quality Improvement; D034622:RNA Interference; D062085:RNA, Long Noncoding / Q000502:physiology*
chemical_list: D062085:RNA, Long Noncoding
keywords: China; Long noncoding RNAs; biogenesis; circular RNAs; lncRNAs