title: Use of accelerometry to investigate physical activity in dogs receiving chemotherapy.
abstract: OBJECTIVE
  To perform a preliminary study to assess whether single-agent palliative or adjuvant chemotherapy has an impact on objectively measured physical activity in dogs.
  
  
  METHODS
  Fifteen dogs with neoplasia (treatment group) wore ActiGraph™ accelerometers for 5-day periods before, during and after receiving single-agent adjuvant or palliative chemotherapy. Mean 5-day total physical activity and time spent in three different intensities of activity (sedentary, light-moderate and vigorous) before, during and after receiving chemotherapy were compared to a group of 15 healthy dogs (control group). Results were also compared within the treatment group across time.
  
  
  RESULTS
  Prior to chemotherapy, treated dogs tended to be less active than control dogs. Treatment group dogs were slightly more active at restaging than they were prior to treatment but had similar activity levels to control dogs. Marked effects of chemotherapy on physical activity were not detected. Physical activity was slightly lower in treated dogs during chemotherapy when compared to control dogs but there was a slight increase in physical activity of treated dogs during chemotherapy when compared with pretreatment recordings. There was little change in the mean 5-day total physical activity between treated dogs during chemotherapy and at restaging but a mild decrease in time spent sedentary and increase in time spent in light-moderate activity at this comparison of time points.
  
  
  CONCLUSIONS
  Single-agent adjuvant or palliative chemotherapy had minimal impact on physical activity levels in dogs with neoplasia.
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH. jenny.helm@glasgow.ac.uk.
authors.forename: J
authors.initials: J
authors.lastname: Helm
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH.
authors.forename: A
authors.initials: A
authors.lastname: McBrearty
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH.
authors.forename: S
authors.initials: S
authors.lastname: Fontaine
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH.
authors.forename: R
authors.initials: R
authors.lastname: Morrison
authors.affiliation: School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH.
authors.forename: P
authors.initials: P
authors.lastname: Yam
mesh_terms: D061725:Accelerometry / Q000662:veterinary; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D004283:Dog Diseases / Q000188:drug therapy / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D008297:Male; D009369:Neoplasms / Q000188:drug therapy / Q000503:physiopathology / Q000662:veterinary*; D010805:Physical Conditioning, Animal; D011446:Prospective Studies; D011788:Quality of Life
chemical_list: D000970:Antineoplastic Agents