title: Impact of gender and sleep position on relationships between anthropometric parameters and obstructive sleep apnea syndrome.
abstract: OBJECTIVE
  Considering the mechanisms by which obesity affects obstructive sleep apnea syndrome (OSAS) and the differences of fat distribution depending on gender, associations between anthropometric parameters, and OSAS may differ depending on gender or sleep position. We analyzed the impact of gender and sleep position on the relationship between fat distribution and development of OSAS.
  
  
  METHODS
  One thousand thirty-two consecutive subjects were analyzed. Recorded anthropometric measurements and overnight polysomnographic data of the subjects were reviewed retrospectively. The presence of OSAS was defined by the respiratory disturbance index (RDI) ≥5 with documented symptoms of excessive daytime sleepiness.
  
  
  RESULTS
  Eight hundred fifty-eight males and 174 females were included. Male subjects had significantly higher body mass index (BMI), larger waist circumference (WC), and lower percent of overall body fat (P < 0.0001, P < 0.0001, and P < 0.0001, respectively). The severity of OSAS was significantly higher in male subjects (RDI 26.9 ± 22.4 in males vs. 10.2 ± 13.8 in females, P < 0.0001). In male subjects, BMI, WC, and overall body fat were significantly associated with severity of OSAS and had larger impacts on supine RDI than lateral RDI. Overall body fat was not associated with severity of OSAS in female subjects, and there were no significant differences of the associations between all anthropometric parameters and RDIs depending on sleep position.
  
  
  CONCLUSIONS
  Evaluation of the correlation of anthropometric data with severity of OSAS should consider sleep position as well as gender.
authors.affiliation: Department of Otolaryngology, Keimyung University School of Medicine, Daegu, South Korea.
authors.forename: Jong In
authors.initials: JI
authors.lastname: Jeong
authors.affiliation: Biostatistics and Clinical Epidemiology Center, Samsung Medical Center, Seoul, South Korea.
authors.forename: Seonhye
authors.initials: S
authors.lastname: Gu
authors.affiliation: Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkunkwan University, Seoul, South Korea.
authors.forename: Juhee
authors.initials: J
authors.lastname: Cho
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, South Korea.
authors.forename: Sang Duk
authors.initials: SD
authors.lastname: Hong
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, South Korea.
authors.forename: Su Jin
authors.initials: SJ
authors.lastname: Kim
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, South Korea.
authors.forename: Hun-Jong
authors.initials: HJ
authors.lastname: Dhong
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, South Korea.
authors.forename: Seung-Kyu
authors.initials: SK
authors.lastname: Chung
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, South Korea. siamkhy@gmail.com.
authors.forename: Hyo Yeol
authors.initials: HY
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D050218:Body Fat Distribution; D006970:Disorders of Excessive Somnolence / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000175:diagnosis*; D017286:Polysomnography; D011187:Posture; D012189:Retrospective Studies; D012737:Sex Factors; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis*; D000070263:Sleep Hygiene; D013223:Statistics as Topic
keywords: Body fat distribution; Gender; Obstructive sleep apnea; Sleep position