title: Internal standards for use in the comprehensive analysis of polychlorinated aromatic hydrocarbons using gas chromatography combined with multiphoton ionization mass spectrometry.
abstract: To decrease health-risks to humans, non-toxic compounds were evaluated for use as internal standards for calibrating data obtained by gas chromatography/multiphoton ionization mass spectrometry (GC-MPI-MS) using an ultraviolet femtosecond laser as the ionization source. The retention time in the mass chromatogram was calibrated using a retention index, in which a series of n-alkanes was employed as internal standards for evaluating the retention times for polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs). To compensate for changes in signal intensity in MPI-MS, the dependence of signal intensity on the laser pulse energy was investigated for the dioxin-like compounds, in addition to five non-toxic aromatic hydrocarbons, that were used as internal standards. Based on their similar behavior,the non-toxic PCDD/PCDF, its13C-isotope, and pentachlorobenzene behave similarly, we conclude that they can be used for calibrating the signal intensities in MPI-MS.
authors.affiliation: College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, China; Division of International Strategy, Center of Future Chemistry, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan. Electronic address: adanli@ysu.edu.cn.
authors.forename: Adan
authors.initials: A
authors.lastname: Li
authors.affiliation: Division of International Strategy, Center of Future Chemistry, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
authors.forename: Totaro
authors.initials: T
authors.lastname: Imasaka
mesh_terms: D000473:Alkanes; D000072338:Dibenzofurans, Polychlorinated / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods / Q000592:standards; D006801:Humans; D011078:Polychlorinated Biphenyls / Q000032:analysis*; D000072317:Polychlorinated Dibenzodioxins / Q000032:analysis*; D012015:Reference Standards
chemical_list: D000473:Alkanes; D000072338:Dibenzofurans, Polychlorinated; D000072317:Polychlorinated Dibenzodioxins; D011078:Polychlorinated Biphenyls
keywords: Dioxin; Internal standard; Mass spectrometry; Multiphoton ionization