title: Building Block Approach for the Synthesis of Sulfoximines.
abstract: A cross-coupling strategy for the preparation of novel sulfoximines via preformed sulfoximidoyl-containing building blocks has been developed. It allows obtaining a wide range of products in good yields under mild reaction conditions, and it can be applied in late-stage functionalizations, as demonstrated by the synthesis of a sulfoximine-based analogue of a recently reported potent valosine-containing protein inhibitor.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University , Landoltweg 1, D-52074 Aachen, Germany.
authors.forename: Anne-Dorothee
authors.initials: AD
authors.lastname: Steinkamp
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University , Landoltweg 1, D-52074 Aachen, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Wiezorek
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University , Landoltweg 1, D-52074 Aachen, Germany.
authors.forename: Felix
authors.initials: F
authors.lastname: Brosge
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University , Landoltweg 1, D-52074 Aachen, Germany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Bolm