title: Stevens-Johnson Syndrome Patient Received Combination Chemotherapy Gemcitabine, Cisplatin, and 5-FU for Biliary Tract Cancer.
abstract: Stevens-Johnson syndrome has been an acute, usually self-limiting disease of the skin and mucous membranes. This case report has presented an evidence of the development Stevens - Johnson syndrome associated with combination chemotherapy administration of 5FU, gemcitabin and cisplatin in a patient with biliary tract cancer. Our case was a 54-year-old woman patient, a case of biliary tract cancer who has developed more severe symptoms of Stevens-Johnson syndrome. Diagnosis has confirmed by skin biopsy of an affected area .The patient has improved with supportive care, and during 25 day occurred recovery. Although Stevens-Johnson syndrome has been a rare toxicity, physicians should pay a special attention to the monitoring of biliary tract cancer patients on combination chemotherapy with 5FU, cisplatin and gemcitabin.
authors.affiliation: Medical Oncologist-Hematologist, Associate Professor, Kermanshah University of Medical Sciences, Kermanshah, IR Iran.
authors.forename: Mozaffar
authors.initials: M
authors.lastname: Aznab
authors.affiliation: Assistant Professor, Kermanshah University of Medical Sciences, Kermanshah, IR Iran.
authors.forename: Mansour
authors.initials: M
authors.lastname: Khazaei
keywords: Chemotherapy; Malignancy; Stevens-Johnson Syndrome