title: Structural regulation by a G-quadruplex ligand increases binding abilities of G-quadruplex-forming aptamers.
abstract: We report that a G-quadruplex-specific compound induced structural changes in G-quadruplex-forming DNA aptamers and stabilized the folded structures, making them suitable for targeted proteins and enhancing their binding properties.
authors.affiliation: Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. ikebu@cc.tuat.ac.jp.
authors.forename: Kaori
authors.initials: K
authors.lastname: Tsukakoshi
authors.affiliation: Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. ikebu@cc.tuat.ac.jp.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Ikuta
authors.affiliation: Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. ikebu@cc.tuat.ac.jp.
authors.forename: Koichi
authors.initials: K
authors.lastname: Abe
authors.affiliation: School of Biotechnology and Bioscience, Tokyo University of Technology, 1404-1 Katakura-cho, Hachioji, Tokyo 192-0982, Japan.
authors.forename: Wataru
authors.initials: W
authors.lastname: Yoshida
authors.affiliation: Graduate School of Science and Engineering, Saitama University, Shimo-okubo 255, Sakura-ku, Saitama 338-8570, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Iida
authors.affiliation: Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. ikebu@cc.tuat.ac.jp.
authors.forename: Yue
authors.initials: Y
authors.lastname: Ma
authors.affiliation: Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. ikebu@cc.tuat.ac.jp.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Nagasawa
authors.affiliation: Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. ikebu@cc.tuat.ac.jp.
authors.forename: Koji
authors.initials: K
authors.lastname: Sode
authors.affiliation: Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan. ikebu@cc.tuat.ac.jp.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Ikebukuro