title: Directing the Viedma ripening of ethylenediammonium sulfate using "Tailor-made" chiral additives.
abstract: Both enantiomers of trans-cyclohexane-1,2-diammonium sulfate and trans-1,2-diphenylethylenediammonium sulfate were used as "tailor-made" additives to direct the mirror-symmetry breaking in the attrition-enhanced deracemization (i.e. Viedma ripening) of conglomerate crystals of ethylenediammonium sulfate (EDS). Isothermal titration calorimetry (ITC) shows chiral recognition of (1R,2R)- and (1S,2S)-1,2-diphenylethylenediamine to EDS crystals where the enthalpy of adsorption of the (1R,2R)-isomer on l-EDS crystals is higher in comparison to that on d-EDS crystals. These results are consistent with a "rule of reversal" mechanism driving the chiral outcome of the Viedma ripening of EDS.
authors.affiliation: Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec H4B 1R6, Canada. Louis.Cuccia@concordia.ca.
authors.forename: Thi Phuong Thao
authors.initials: TP
authors.lastname: Nguyen
authors.affiliation: Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec H4B 1R6, Canada. Louis.Cuccia@concordia.ca.
authors.forename: Pui Shan Monica
authors.initials: PS
authors.lastname: Cheung
authors.affiliation: Bar-Ilan University, Department of Chemistry, Ramat Gan, Israel. Yitzhak.Mastai@biu.ac.il.
authors.forename: Liora
authors.initials: L
authors.lastname: Werber
authors.affiliation: Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec H4B 1R6, Canada. Louis.Cuccia@concordia.ca.
authors.forename: Jacinthe
authors.initials: J
authors.lastname: Gagnon
authors.affiliation: Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec H4B 1R6, Canada. Louis.Cuccia@concordia.ca.
authors.forename: Reajean
authors.initials: R
authors.lastname: Sivakumar
authors.affiliation: Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec H4B 1R6, Canada. Louis.Cuccia@concordia.ca.
authors.forename: Cameron
authors.initials: C
authors.lastname: Lennox
authors.affiliation: Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec H4B 1R6, Canada. Louis.Cuccia@concordia.ca.
authors.forename: Aaron
authors.initials: A
authors.lastname: Sossin
authors.affiliation: Bar-Ilan University, Department of Chemistry, Ramat Gan, Israel. Yitzhak.Mastai@biu.ac.il.
authors.forename: Yitzhak
authors.initials: Y
authors.lastname: Mastai
authors.affiliation: Department of Chemistry & Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec H4B 1R6, Canada. Louis.Cuccia@concordia.ca.
authors.forename: Louis A
authors.identifier: http://orcid.org/0000-0001-7999-2249
authors.initials: LA
authors.lastname: Cuccia