title: Interferons as Therapy for Viral and Neoplastic Diseases: From Panacea to Pariah to Paragon.
abstract: For more than 20 years after the excitement engendered by their discovery in 1957 as antiviral agents, there were no significant clinical uses of interferons; however, following their cloning they have been employed as effective treatment for several viral, autoimmune, and neoplastic diseases.
authors.affiliation: Department of Pathology, F. Edward Hébert School of Medicine, USUHS/4301 Jones Bridge Rd, Bethesda, MD 20814, USA. rfriedman@usuhs.mil.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Friedman
authors.affiliation: Department of Pathology, F. Edward Hébert School of Medicine, USUHS/4301 Jones Bridge Rd, Bethesda, MD 20814, USA. scontente@usuhs.mil.
authors.forename: Sara
authors.initials: S
authors.lastname: Contente
keywords: cancer; clinical applications; infectious diseases; interferon; multiple sclerosis