title: Association between the Gensini Score and Carotid Artery Stenosis.
abstract: OBJECTIVE
  The aim of this study was to evaluate the association between the extent of coronary artery disease assessed by the Gensini score and/or the SYNTAX score and the significant carotid stenosis in patients undergoing coronary artery bypass grafting (CABG).
  
  
  METHODS
  A total of 225 patients who had carotid doppler ultrasonography prior to CABG were included retrospectively. Significant coronary artery disease was assumed as a lumen diameter stenosis of ≥50% in any of the major epicardial coronary arteries. The severity of carotid stenosis was determined by B-mode and duplex ultrasonography. Clinically significant carotid stenosis was defined as peak systolic velocity greater than 125 cm/s.
  
  
  RESULTS
  The mean value of SYNTAX score and Gensini score was highest in patients allocated to significant carotid stenosis (22.98±7.32, p<0.001 and 77.40±32.35, p<0.001, respectively). The other risk factors for significant carotid stenosis were found to be male gender (p=0.029), carotid bruit (p<0.001), diabetes (p=0.021), left main disease (p=0.002), 3-vessel disease (p=0.008), chronic total coronary occlusion (p=0.001), and coronary artery calcification (p=0.001) in univariate analysis. However, only the Gensini score (odds ratio[OR]=1.030, p=0.004), carotid bruit (OR=0.068, p<0.001), and male gender (OR=0.190, p=0.003) were the independent predictors. The Gensini score cut off value predicting significant carotid stenosis was 50.5 with 77% sensitivity (p<0.001).
  
  
  CONCLUSIONS
  The Gensini score may be used to identify patients at high risk for significant carotid stenosis prior to CABG.
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Anil
authors.initials: A
authors.lastname: Avci
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Fidan
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Mehmet Mustafa
authors.initials: MM
authors.lastname: Tabakçı
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Toprak
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Elnur
authors.initials: E
authors.lastname: Alizade
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Emrah
authors.initials: E
authors.lastname: Acar
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Emrah
authors.initials: E
authors.lastname: Bayam
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Muhammet
authors.initials: M
authors.lastname: Tellice
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Naser
authors.affiliation: Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Kargın
keywords: Carotid artery disease; Coronary atherosclerosis; Doppler ultrasonography