title: Efficacy of an anti-CD22 antibody-monomethyl auristatin E conjugate in a preclinical xenograft model of precursor B-cell acute lymphoblastic leukemia.
authors.affiliation: a Department of Pediatrics , University of California , Davis , CA , USA.
authors.forename: Sakiko
authors.initials: S
authors.lastname: Yoshida
authors.affiliation: b Department of Internal Medicine , University of California , Davis , CA , USA.
authors.forename: Emily
authors.initials: E
authors.lastname: Tuscano
authors.affiliation: a Department of Pediatrics , University of California , Davis , CA , USA.
authors.forename: Connie
authors.initials: C
authors.lastname: Duong
authors.affiliation: a Department of Pediatrics , University of California , Davis , CA , USA.
authors.forename: Jong
authors.initials: J
authors.lastname: Chung
authors.affiliation: c Department of Public Health Sciences , University of California , Davis , CA , USA.
authors.forename: Yueju
authors.initials: Y
authors.lastname: Li
authors.affiliation: c Department of Public Health Sciences , University of California , Davis , CA , USA.
authors.forename: Laurel
authors.initials: L
authors.lastname: Beckett
authors.affiliation: b Department of Internal Medicine , University of California , Davis , CA , USA.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Tuscano
authors.affiliation: a Department of Pediatrics , University of California , Davis , CA , USA.
authors.forename: Noriko
authors.initials: N
authors.lastname: Satake
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000494:pharmacology*; D000074322:Antineoplastic Agents, Immunological / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D002675:Child, Preschool; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D006801:Humans; D018796:Immunoconjugates / Q000737:chemistry / Q000494:pharmacology*; D008297:Male; D051379:Mice; D058990:Molecular Targeted Therapy; D009842:Oligopeptides / Q000737:chemistry; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D051918:Sialic Acid Binding Ig-like Lectin 2 / Q000037:antagonists & inhibitors*; D023041:Xenograft Model Antitumor Assays
chemical_list: D000911:Antibodies, Monoclonal; D000074322:Antineoplastic Agents, Immunological; D018796:Immunoconjugates; D009842:Oligopeptides; D051918:Sialic Acid Binding Ig-like Lectin 2; C495575:monomethyl auristatin E