title: Modified Cognitive Behavior Therapy for Severe, Treatment-Resistant Obsessive-Compulsive Disorder in an Adolescent With Autism Spectrum Disorder.
abstract: There is a high rate of comorbidity between obsessive-compulsive disorder (OCD) and autism spectrum disorders (ASD). Standard cognitive-behavior therapy (CBT) protocols have been shown to be less effective in treating OCD in young people with ASD than in typically developing youth. This case study describes the treatment of an adolescent boy with severe, treatment-resistant OCD and ASD using a modified CBT approach. Modifications to a standard evidence-based CBT for OCD protocol included extended psychoeducation about anxiety; regular home-based sessions; and increased involvement of systems, including family and school. Multi-informant outcome data indicated significant improvements in OCD symptoms over the course of treatment with gains being maintained over a 12-month follow-up period. These findings demonstrate the potential efficacy of modified CBT for pediatric OCD in the context of ASD.
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London. georgina.1.krebs@kcl.ac.uk.|OCD and Related Disorders Clinic for Young People, South London and Maudsley NHS Foundation Trust. georgina.1.krebs@kcl.ac.uk.
authors.forename: Georgina
authors.initials: G
authors.lastname: Krebs
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London.
authors.forename: Kim
authors.initials: K
authors.lastname: Murray
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London.|OCD and Related Disorders Clinic for Young People, South London and Maudsley NHS Foundation Trust.
authors.forename: Amita
authors.initials: A
authors.lastname: Jassi
mesh_terms: D000293:Adolescent; D000067877:Autism Spectrum Disorder / Q000628:therapy*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000628:therapy*; D012720:Severity of Illness Index
keywords: autism spectrum disorder; cognitive behavior therapy; exposure with response prevention; obsessive-compulsive disorder