title: An inverse problem in estimating the laser irradiance and thermal damage in laser-irradiated biological tissue with a dual-phase-lag model.
abstract: The aim of this study is to solve an inverse heat conduction problem to estimate the unknown time-dependent laser irradiance and thermal damage in laser-irradiated biological tissue from the temperature measurements taken within the tissue. The dual-phase-lag model is considered in the formulation of heat conduction equation. The inverse algorithm used in the study is based on the conjugate gradient method and the discrepancy principle. The effect of measurement errors and measurement locations on the estimation accuracy is also investigated. Two different examples of laser irradiance are discussed. Results show that the unknown laser irradiance and thermal damage can be predicted precisely by using the present approach for the test cases considered in this study.
authors.affiliation: a Clean Energy Center, Department of Mechanical Engineering , Kun Shan University , Tainan , Taiwan, ROC.
authors.forename: Yu-Ching
authors.initials: YC
authors.lastname: Yang
authors.affiliation: a Clean Energy Center, Department of Mechanical Engineering , Kun Shan University , Tainan , Taiwan, ROC.
authors.forename: Haw-Long
authors.initials: HL
authors.lastname: Lee
authors.affiliation: a Clean Energy Center, Department of Mechanical Engineering , Kun Shan University , Tainan , Taiwan, ROC.
authors.forename: Win-Jin
authors.initials: WJ
authors.lastname: Chang
authors.affiliation: b Department of Aeronautics and Astronautics , National Cheng Kung University , Tainan , Taiwan, ROC.
authors.forename: Wen-Lih
authors.initials: WL
authors.lastname: Chen
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D007834:Lasers; D008962:Models, Theoretical; D009716:Numerical Analysis, Computer-Assisted; D013696:Temperature; D013814:Thermal Conductivity
keywords: Inverse problem; biological tissue; dual-phase-lag; laser irradiance