title: Graft Reconditioning before Liver Transplantation.
abstract: BACKGROUND
  The high demand for livers for transplantation has led to organs of limited quality being accepted to expand the donor pool. This is associated with inferior outcomes due to more pronounced preservation injury. Accordingly, recent research has aimed to develop preservation modalities for improved preservation as well as strategies for liver viability assessment and liver reconditioning.
  
  
  METHODS
  The PubMed database was searched using the terms 'perfusion', 'liver', 'preservation', and 'reconditioning' in various combinations, and the according literature was reviewed.
  
  
  RESULTS
  Several perfusion techniques have been developed in recent years with the potential for liver reconditioning. Preclinical and first emerging clinical data suggest feasibility, safety, and superiority over the current gold standard of cold storage.
  
  
  CONCLUSIONS
  This review outlines current advances in the field of liver preservation with an emphasis on liver reconditioning methods.
authors.affiliation: General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany.
authors.forename: Dieter P
authors.initials: DP
authors.lastname: Hoyer
authors.affiliation: General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Minor
keywords: Extended criteria donors; Liver preservation; Liver viability assessment; Reconditioning