title: Enantioselective Dearomative [3+2] Cycloaddition Reactions of Benzothiazoles.
abstract: A highly enantioselective dearomative [3+2] cycloaddition of benzothiazole has been successfully developed. A wide range of benzothiazoles and cyclopropane-1,1-dicarboxylates are suitable substrates for this reaction. The desired hydropyrrolo[2,1-b]thiazole compounds were obtained in excellent enantioselectivity and yields (up to 97 % ee and 97 % yield). With the same catalytic system, a highly efficient kinetic resolution of 2-substituted cyclopropane-1,1-dicarboxylates was also realized.
authors.affiliation: School of Environment, Henan Normal University, Xinxiang, 453007, China.|School of Chemistry and Chemical Engineering, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang, 453007, China.
authors.forename: Dong-Chao
authors.initials: DC
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang, 453007, China.
authors.forename: Ming-Sheng
authors.initials: MS
authors.lastname: Xie
authors.affiliation: School of Environment, Henan Normal University, Xinxiang, 453007, China. ghm@htu.edu.cn.|School of Chemistry and Chemical Engineering, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang, 453007, China. ghm@htu.edu.cn.
authors.forename: Hai-Ming
authors.initials: HM
authors.lastname: Guo
authors.affiliation: School of Chemistry and Chemical Engineering, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang, 453007, China.
authors.forename: Gui-Rong
authors.initials: GR
authors.lastname: Qu
authors.affiliation: School of Chemistry and Chemical Engineering, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang, 453007, China.
authors.forename: Meng-Cheng
authors.initials: MC
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, China. slyou@sioc.ac.cn.
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You
keywords: Lewis acids; cycloadditions; enantioselectivity; magnesium; small-ring compounds