title: Breaking up Prolonged Sitting does not Alter Postprandial Glycemia in Young, Normal-Weight Men and Women.
abstract: A randomized, controlled, cross-over study was used to investigate the effects of breaking up prolonged sitting with low intensity physical activity on postprandial blood glucose concentrations in healthy, young, normal-weight adults. 14 men (n=6) and women (n=8) were assigned to 2.5 h of prolonged sitting (CON) and 2.5 h of prolonged sitting with 2-min bouts of walking every 20 min (LIPA). After ingesting a standardized test drink, capillary blood was sampled every 10 min to establish a postprandial blood glucose profile. Based on individual glucose responses, peak blood glucose, time-to-peak glucose, and incremental area under the glucose curve (iAUC) were determined. Paired sample t-tests were used to detect differences between trials. Peak blood glucose (p=0.55) and iAUC (CON: 252 mmol·L-1·2.5 h-1[163-340]; LIPA: 214 mmol·L-1·2.5 h-1[146-282];p=0.45) were not different between trials. Also, time-to-peak glucose was not different between LIPA and CON (p=0.37). Taking advantage of high temporal resolution blood glucose profiles, we showed that breaking up prolonged sitting with low-intensity physical activity does not alter the postprandial blood glucose response in young, healthy, normal-weight adults. Our results indicate that postprandial glycemic control is maintained during prolonged sitting in young, healthy adults.
authors.affiliation: Health Science and Technology, Aalborg University, Aalborg, Denmark.
authors.forename: R K
authors.initials: RK
authors.lastname: Hansen
authors.affiliation: Health Science and Technology, Aalborg University, Aalborg, Denmark.
authors.forename: J B
authors.initials: JB
authors.lastname: Andersen
authors.affiliation: Health Science and Technology, Aalborg University, Aalborg, Denmark.
authors.forename: A S
authors.initials: AS
authors.lastname: Vinther
authors.affiliation: Health Science and Technology, Aalborg University, Aalborg, Denmark.
authors.forename: U
authors.initials: U
authors.lastname: Pielmeier
authors.affiliation: Health Science and Technology, Aalborg University, Aalborg, Denmark.
authors.forename: R G
authors.initials: RG
authors.lastname: Larsen
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D008297:Male; D019518:Postprandial Period / Q000502:physiology*; D011187:Posture; D057185:Sedentary Behavior; D016138:Walking / Q000502:physiology*; D055815:Young Adult
chemical_list: D001786:Blood Glucose