title: Low-grade papillary adenocarcinoma of nasopharynx with expression of thyroid transcription factor-1: Case report and review of literature.
abstract: Low-grade papillary adenocarcinomas with expression of thyroid transcription factor-1 (TTF-1) are rare tumors of the nasopharynx, with only a few cases reported in the literature. These tumors have an excellent prognosis following complete surgical excision. We report a 13-year-old boy with this rare tumor in the nasopharynx. The patient underwent complete surgical excision of the tumor and was on follow-up without evidence of recurrence.
authors.affiliation: Division of Pediatric Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
authors.forename: Binitha
authors.initials: B
authors.lastname: Rajeswari
authors.affiliation: Division of Pediatric Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
authors.forename: Reghu K
authors.initials: RK
authors.lastname: Sukumaran Nair
authors.affiliation: Division of Pediatric Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
authors.forename: Kusumakumary
authors.initials: K
authors.lastname: Parukuttyamma
authors.affiliation: Division of Pathology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India.
authors.forename: Anitha
authors.initials: A
authors.lastname: Mathews
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D000293:Adolescent; D014408:Biomarkers, Tumor / Q000032:analysis; D006257:Head / Q000000981:diagnostic imaging; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008853:Microscopy; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D009305:Nasopharynx / Q000473:pathology*; D009687:Nuclear Proteins / Q000032:analysis*; D000074482:Thyroid Nuclear Factor 1; D014057:Tomography, X-Ray Computed; D014157:Transcription Factors / Q000032:analysis*; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; C000614412:NKX2-1 protein, human; D009687:Nuclear Proteins; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors