title: Vision Restoration Becomes Druggable.
abstract: In this issue of Neuron, Tochitsky et al. (2016) have identified the mechanism by which small-molecule photoswitches enter and specifically activate retinal OFF-ganglion cells in degenerated retinas. This drug development is a tremendous step toward the treatment of blindness, regardless of the underlying mutation.
authors.affiliation: Center for Regenerative Therapies Dresden, TU Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.
authors.forename: Simon Darius
authors.initials: SD
authors.lastname: Klapper
authors.affiliation: Center for Regenerative Therapies Dresden, TU Dresden, Fetscherstrasse 105, 01307 Dresden, Germany. Electronic address: volker.busskamp@crt-dresden.de.
authors.forename: Volker
authors.initials: V
authors.lastname: Busskamp
mesh_terms: D000818:Animals; D017952:Ganglia, Invertebrate; D006801:Humans; D009154:Mutation; D009474:Neurons; D012160:Retina; D012162:Retinal Degeneration / Q000235:genetics*; D012165:Retinal Ganglion Cells