title: Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone.
authors.affiliation: Department of Immunology Discovery, Genentech, South San Francisco, Calif.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Ramirez-Carrozzi
authors.affiliation: Department of Immunology Discovery, Genentech, South San Francisco, Calif.
authors.forename: Arivazhagan
authors.initials: A
authors.lastname: Sambandam
authors.affiliation: Department of Translational Immunology, Genentech, South San Francisco, Calif.
authors.forename: Meijuan
authors.initials: M
authors.lastname: Zhou
authors.affiliation: Department of Translational Immunology, Genentech, South San Francisco, Calif.
authors.forename: Donghong
authors.initials: D
authors.lastname: Yan
authors.affiliation: Department of Translational Immunology, Genentech, South San Francisco, Calif.
authors.forename: Jing
authors.initials: J
authors.lastname: Kang
authors.affiliation: Department of Translational Immunology, Genentech, South San Francisco, Calif.
authors.forename: Xiumin
authors.initials: X
authors.lastname: Wu
authors.affiliation: Department of Translational Immunology, Genentech, South San Francisco, Calif.
authors.forename: Eric
authors.initials: E
authors.lastname: Suto
authors.affiliation: Department of Pathology, Genentech, South San Francisco, Calif.
authors.forename: Miriam
authors.initials: M
authors.lastname: Baca
authors.affiliation: Department of Pathology, Genentech, South San Francisco, Calif.
authors.forename: Cary
authors.initials: C
authors.lastname: Austin
authors.affiliation: Department of Translational Immunology, Genentech, South San Francisco, Calif.
authors.forename: Min
authors.initials: M
authors.lastname: Xu
authors.affiliation: Department of Translational Immunology, Genentech, South San Francisco, Calif.
authors.forename: Wyne
authors.initials: W
authors.lastname: Lee
authors.affiliation: Department of Immunology Discovery, Genentech, South San Francisco, Calif. Electronic address: rajitap@gene.com.
authors.forename: Rajita
authors.initials: R
authors.lastname: Pappu
mesh_terms: D000818:Animals; D019138:Antibodies, Blocking / Q000276:immunology / Q000494:pharmacology*; D001249:Asthma / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D004195:Disease Models, Animal; D007249:Inflammation / Q000188:drug therapy / Q000235:genetics / Q000276:immunology / Q000473:pathology; D018793:Interleukin-13 / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000276:immunology; D000067596:Interleukin-33 / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000276:immunology; D051379:Mice; D018345:Mice, Knockout; D009559:Nippostrongylus / Q000276:immunology*; D015398:Signal Transduction / Q000187:drug effects*; D017206:Strongylida Infections / Q000188:drug therapy / Q000235:genetics / Q000276:immunology* / Q000473:pathology
chemical_list: D019138:Antibodies, Blocking; C506535:Il33 protein, mouse; D018793:Interleukin-13; D000067596:Interleukin-33