title: Computational design and engineering of polymeric orthodontic aligners.
abstract: Transparent and removable aligners represent an effective solution to correct various orthodontic malocclusions through minimally invasive procedures. An aligner-based treatment requires patients to sequentially wear dentition-mating shells obtained by thermoforming polymeric disks on reference dental models. An aligner is shaped introducing a geometrical mismatch with respect to the actual tooth positions to induce a loading system, which moves the target teeth toward the correct positions. The common practice is based on selecting the aligner features (material, thickness, and auxiliary elements) by only considering clinician's subjective assessments. In this article, a computational design and engineering methodology has been developed to reconstruct anatomical tissues, to model parametric aligner shapes, to simulate orthodontic movements, and to enhance the aligner design. The proposed approach integrates computer-aided technologies, from tomographic imaging to optical scanning, from parametric modeling to finite element analyses, within a 3-dimensional digital framework. The anatomical modeling provides anatomies, including teeth (roots and crowns), jaw bones, and periodontal ligaments, which are the references for the down streaming parametric aligner shaping. The biomechanical interactions between anatomical models and aligner geometries are virtually reproduced using a finite element analysis software. The methodology allows numerical simulations of patient-specific conditions and the comparative analyses of different aligner configurations. In this article, the digital framework has been used to study the influence of various auxiliary elements on the loading system delivered to a maxillary and a mandibular central incisor during an orthodontic tipping movement. Numerical simulations have shown a high dependency of the orthodontic tooth movement on the auxiliary element configuration, which should then be accurately selected to maximize the aligner's effectiveness.
authors.affiliation: Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Barone
authors.affiliation: Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Paoli
authors.affiliation: Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy.
authors.forename: A V
authors.initials: AV
authors.lastname: Razionale
authors.affiliation: Department of Civil and Industrial Engineering, University of Pisa, Pisa, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Savignano
mesh_terms: D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D007180:Incisor; D003765:Models, Dental; D008962:Models, Theoretical; D009970:Orthodontics / Q000295:instrumentation*; D011108:Polymers; D012984:Software; D014087:Tooth Movement Techniques / Q000295:instrumentation*
chemical_list: D011108:Polymers
keywords: Computational engineering; Computer-aided design; Finite element analysis; Orthodontic treatment; Patient-specific modeling; Polymeric aligner