title: Biological Functions and Clinical Applications of Anti-Müllerian Hormone in Stallions and Mares.
abstract: Anti-Müllerian hormone (AMH) plays a major role in sexual differentiation, Leydig cell differentiation, and folliculogenesis. In addition, AMH has clinical value in equine practice. In stallions, AMH can serve as an endocrine marker for equine cryptorchidism and as an immunohistochemical marker for Sertoli cell tumors. Considering that AMH is also an ovarian specific product, intact mares can be differentiated from ovariectomized mares. Peripheral AMH concentrations reflect the follicular population in mares, and therefore, are useful in the assessment of ovarian reserve and reproductive life-span of aged mares. Last, AMH is particularly suitable as a diagnostic marker for equine granulosa cell tumors.
authors.affiliation: Department of Equine Science, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 114, Utrecht 3584 CM, The Netherlands. Electronic address: a.claes@uu.nl.
authors.forename: Anthony N J
authors.initials: AN
authors.lastname: Claes
authors.affiliation: Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, 1400 Nicholasville Road, Lexington, KY, 40546-0099 USA.
authors.forename: Barry A
authors.initials: BA
authors.lastname: Ball
mesh_terms: D000818:Animals; D054304:Anti-Mullerian Hormone / Q000097:blood / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood; D030762:Estrous Cycle / Q000502:physiology; D005260:Female; D006734:Horse Diseases / Q000097:blood; D006736:Horses / Q000502:physiology*; D008297:Male; D006080:Ovarian Follicle / Q000502:physiology
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Anti-Müllerian hormone; Cryptorchidism; Equine; Equine granulosa cell tumor; Mare; Ovarian reserve; Sertoli cell tumor; Stallion