title: Spatial Memory in the Progeny of Rats Subjected to Different Types of Experimental Preeclampsia.
abstract: Spatial memory was studied in 2-month-old offspring of rats subjected to different types of experimental preeclampsia (replacement of drinking water with 1.8% NaCl from day 1 to 21 of gestation or intraperitoneal administration of non-selective NO-synthase inhibitor L-NAME to pregnant rats in a daily dose of 25 mg/kg for 7 days on gestation days 14-20). Spatial memory was evaluated in an elevated 8-arm radial maze. Both types of experimental preeclampsia impaired spatial (long-term and short-term) memory and can be used in the development of drugs correcting negative effects of this pregnancy complication on memory.
authors.affiliation: Volgograd State Medical University, Volgograd, Russia.
authors.forename: V N
authors.initials: VN
authors.lastname: Perfilova
authors.affiliation: Volgograd State Medical University, Volgograd, Russia. g.a.zhakupova@yandex.ru.
authors.forename: G A
authors.initials: GA
authors.lastname: Zhakupova
authors.affiliation: Volgograd State Medical University, Volgograd, Russia.
authors.forename: L I
authors.initials: LI
authors.lastname: Lashchenova
authors.affiliation: Volgograd State Medical University, Volgograd, Russia.|Research Institute for Pharmacology of Volgograd State Medical University, Volgograd, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Lebedeva
authors.affiliation: Volgograd State Medical University, Volgograd, Russia.
authors.forename: I N
authors.initials: IN
authors.lastname: Tyurenkov
mesh_terms: D000818:Animals; D005260:Female; D018782:Maze Learning; D008569:Memory Disorders / Q000209:etiology*; D011225:Pre-Eclampsia / Q000523:psychology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000209:etiology* / Q000523:psychology; D051381:Rats; D065852:Spatial Memory
keywords: experimental preeclampsia; spatial memory