title: Effect of Dissection and Reconstruction of Palatal Muscles on Morphological Features and Ultrastructure of the Oral Musculature in Cats.
abstract: The study was designed to determine the effect of dissection and reconstruction of palatal muscles on muscle morphology in cats. 27 cats were randomly divided into three groups according to the extent of muscle dissection from the palatal midline. All dissections were performed from the posterior border of the hard palate, and the muscles were allowed to reconstruct over time. The morphological features were determined by hematoxylin and eosin staining of tissue sections, and ultrastructure was observed under a transmission electron microscope. As a result, no obvious differences were evident in the morphological features or ultrastructure of animals in the <1/3rd and 1/3rd-2/3rd area groups. In the >2/3rd area group, the muscles fibers were disordered and inflammatory cell infiltration and naïve muscle cells were found at one month after surgery. At the second and third month after surgery, the muscle fibers showed regular alignment, the naïve muscle fibers gradually matured, and the number of infiltrating inflammatory cells decreased. Muscle ultrastructure analysis revealed that myocommata were correctly aligned, and the Z line was more distinct. In conclusion, extensive dissection of palatal muscles does not result in fibrosis. Injury to oral musculature can be repaired and the musculature regenerated over time.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Han
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Qi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
authors.forename: Wenguang
authors.identifier: 0000-0003-1508-1766
authors.initials: W
authors.lastname: Xu
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Shen
authors.affiliation: State Key Laboratory of Oral Diseases, Department of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
authors.forename: Bing
authors.identifier: 0000-0002-7795-3235
authors.initials: B
authors.lastname: Shi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
authors.forename: Yong
authors.identifier: 0000-0002-0656-1728
authors.initials: Y
authors.lastname: Lu
mesh_terms: D000818:Animals; D002415:Cats; D004210:Dissection; D008297:Male; D019647:Oral Surgical Procedures; D010156:Palatal Muscles / Q000473:pathology / Q000601:surgery* / Q000648:ultrastructure*; D019651:Plastic Surgery Procedures / Q000379:methods*; D016896:Treatment Outcome