title: Acute onset blindness: a case of optic neuritis and review of childhood optic neuritis.
abstract: Optic neuritis (ON) is an acquired disorder of the optic nerve due to inflammation, demyelination or degeneration. We report a child who presented with acute onset bilateral visual loss who, following a diagnosis of ON, was treated and had excellent visual recovery. Paediatric ON is considered to be different clinical entity to adult ON. Although in children ON is usually parainfectious or postinfectious, it can be the first presenting feature of multiple sclerosis or neuromyelitis optica spectrum disease. In this paper, we discuss the literature on treatment of ON and prediction of risk of recurrence.
authors.affiliation: Department of Paediatric Neurology, Evelina London Children's Hospital at Guy's and St Thomas' NHS Trust, London, UK.
authors.forename: Sithara
authors.initials: S
authors.lastname: Ramdas
authors.affiliation: Children's Eye Department, Guy's and St Thomas' NHS Trust, London, UK.
authors.forename: Danny
authors.initials: D
authors.lastname: Morrison
authors.affiliation: Department of Paediatric Neurology, Evelina London Children's Hospital at Guy's and St Thomas' NHS Trust, London, UK.
authors.forename: Michael
authors.initials: M
authors.lastname: Absoud
authors.affiliation: Department of Paediatric Neurology, Evelina London Children's Hospital at Guy's and St Thomas' NHS Trust, London, UK.
authors.forename: Ming
authors.initials: M
authors.lastname: Lim
mesh_terms: D000208:Acute Disease; D000284:Administration, Oral; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001766:Blindness / Q000209:etiology*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009902:Optic Neuritis / Q000150:complications* / Q000175:diagnosis; D011239:Prednisolone / Q000008:administration & dosage
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone