title: Weight loss after head and neck cancer: A dynamic relationship with depressive symptoms.
abstract: Weight loss and depressive symptoms are critical head and neck cancer outcomes, yet their relation over the illness course is unclear.
  
  
  
  Associations between self-reported depressive symptoms and objective weight loss across the year after head and neck cancer diagnosis were examined using growth curve modeling techniques (n = 564).
  
  
  
  A reciprocal covariation pattern emerged-changes in depressive symptoms over time were associated with same-month changes in weight loss (t [1148] = 2.05; p = .041), and changes in weight loss were associated with same-month changes in depressive symptoms (t [556] = 2.43; p = .015). To the extent that depressive symptoms increased, patients lost incrementally more weight than was lost due to the passage of time and vice versa. Results also suggested that pain and eating-related quality of life might explain the reciprocal association between depressive symptoms and weight loss.
  
  
  
  In head and neck cancer, a transactional interplay between depressive symptoms and weight loss unfolds over time. © 2016 Wiley Periodicals, Inc. Head Neck 39: 370-379, 2017.
authors.affiliation: Department of Psychology, The University of Iowa, Iowa City, Iowa.
authors.forename: Julia R
authors.initials: JR
authors.lastname: Van Liew
authors.affiliation: Department of Psychology, The University of Nebraska - Lincoln, Lincoln, Nebraska.
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Brock
authors.affiliation: Department of Psychology, The University of Iowa, Iowa City, Iowa.|Department of Internal Medicine, The University of Iowa College of Medicine, Iowa City, Iowa.
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Christensen
authors.affiliation: Department of Otolaryngology - Head and Neck Surgery, The University of Iowa College of Medicine, Iowa City, Iowa.
authors.forename: Lucy Hynds
authors.initials: LH
authors.lastname: Karnell
authors.affiliation: Department of Otolaryngology - Head and Neck Surgery, The University of Iowa College of Medicine, Iowa City, Iowa.
authors.forename: Nitin A
authors.initials: NA
authors.lastname: Pagedar
authors.affiliation: Department of Otolaryngology, Grande Ronde Hospitals and Clinics, La Grande, Oregon.
authors.forename: Gerry F
authors.initials: GF
authors.lastname: Funk
mesh_terms: D000368:Aged; D015331:Cohort Studies; D015897:Comorbidity; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology / Q000601:surgery; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D018570:Risk Assessment; D057566:Self Report; D014481:United States / Q000453:epidemiology; D015431:Weight Loss
keywords: depressive symptoms; head and neck cancer; nutrition; weight loss