title: Expanding frontiers in weight-control research explored by young investigators.
abstract: At the 93rd annual meeting of the Physiological Society of Japan, a symposium entitled "Expanding frontiers in weight-control research explored by young investigators" was organized. The latest research on weight control was presented by young up-and-coming investigators. The symposium consisted of the following presentations: Gastrointestinal brush cells, immunity, and energy homeostasis; Impact of a brown rice-derived bioactive product on feeding regulation and fuel metabolism; A novel G protein-coupled receptor-regulated neuronal signaling pathway triggers sustained orexigenic effects; and NMDA receptor co-agonist D-serine regulates food preference. These four talks presented at the symposium were summarized as a series of short reviews in this review.
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan. ayishi@mail.ecc.u-tokyo.ac.jp.
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Ishimaru
authors.affiliation: Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Internal Medicine), Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan. ch.kozuka@gmail.com.
authors.forename: Chisayo
authors.initials: C
authors.lastname: Kozuka
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan. anakaj@mail.ecc.u-tokyo.ac.jp.
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Nakajima
authors.affiliation: Laboratory for Metabolic Signaling. Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan. tsutomus@gunma-u.ac.jp.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sasaki
mesh_terms: D000818:Animals; D004734:Energy Metabolism / Q000502:physiology*; D041981:Gastrointestinal Tract / Q000378:metabolism*; D006801:Humans; D009474:Neurons / Q000378:metabolism; D009765:Obesity / Q000378:metabolism*; D012106:Research; D015398:Signal Transduction / Q000502:physiology*
keywords: Anorexia; Appetite; DREADD; Type 2 immune response; γ-Oryzanol