title: Low startle magnitude may be a behavioral marker of vulnerability to cocaine addiction.
abstract: Cocaine addicted men have low startle magnitude persisting during prolonged abstinence. Low startle rats show greater cocaine self-administration than high startle rats. Low startle may be a marker of a vulnerability to heightened cocaine-related behaviors in rats and similarly may be a marker of vulnerability to cocaine addiction in humans.
authors.affiliation: Department of Psychology, Emory University, 201 Dowman Drive, Atlanta, Georgia 30322.|Yerkes National Primate Research Center, 954 Gatewood Road, NE Atlanta, Georgia, 30329.
authors.forename: Marina G
authors.initials: MG
authors.lastname: Wheeler
authors.affiliation: Mental Health Service Line, Atlanta Veterans Affairs Medical Center, 1670 Clairmont Road, Decatur, Georgia, 30033.|Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 100 Woodruff Circle, Atlanta, Georgia, 30322.
authors.forename: Erica
authors.initials: E
authors.lastname: Duncan
authors.affiliation: Department of Psychology, Emory University, 201 Dowman Drive, Atlanta, Georgia 30322.|Yerkes National Primate Research Center, 954 Gatewood Road, NE Atlanta, Georgia, 30329.|Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 100 Woodruff Circle, Atlanta, Georgia, 30322.
authors.forename: Michael
authors.initials: M
authors.lastname: Davis
mesh_terms: D000818:Animals; D019970:Cocaine-Related Disorders / Q000503:physiopathology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012022:Reflex, Acoustic; D013216:Reflex, Startle
keywords: acoustic startle; cocaine; dopamine; novelty preference; self-administration