title: Utility of the adverse outcome pathway concept in drug development.
authors.affiliation: a Center for Alternatives to Animal Testing (CAAT) , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.|b Center for Alternatives to Animal Testing (CAAT), Pharmacology and Toxicology , University of Konstanz , Konstanz , Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Hartung
mesh_terms: D015195:Drug Design; D006801:Humans; D018570:Risk Assessment / Q000379:methods; D018675:Toxicity Tests / Q000379:methods*
keywords: Toxicology for the 21st century; chemicals; hazard; mechanistic toxicology; omics technologies