title: A Review of Topical Diclofenac Use in Musculoskeletal Disease.
abstract: Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed medications for the treatment of musculoskeletal disorders. Osteoarthritis is the most common form of arthritis in humans and its prevalence rises with age. Oral NSAIDs have potential associated toxicities that must be monitored for and can limit the use of these drugs in certain populations including people of older age. Topical NSAIDs are now being recognized as an option for the treatment strategy of osteoarthritis. We review the efficacy and safety of one of the most common topical NSAIDS, topical diclofenac, for the treatment of osteoarthritis.
authors.affiliation: Division of Rheumatology, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan S7N 0W8, Canada. bindu.nair@saskatoonhealthregion.ca.
authors.forename: Bindu
authors.initials: B
authors.lastname: Nair
authors.affiliation: Division of Rheumatology, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan S7N 0W8, Canada. r.gjevre@usask.ca.
authors.forename: Regina
authors.initials: R
authors.lastname: Taylor-Gjevre
keywords: NSAIDs; diclofenac; musculoskeletal; osteoarthritis