title: Anaphylactic shock caused by intramuscular injection of midazolam during the perioperative period: a case report.
abstract: Although anaphylactic shock during the perioperative period is rare, it can be lethal due to severe cardiovascular and respiratory collapse. Midazolam is generally used as premedication for relieving anxiety about the operation, and the danger of anaphylactic shock after intramuscular injection is not widely recognized. We report the first case of anaphylactic shock occurring during the perioperative period after intramuscular injection of midazolam. Since anaphylactic shock after intramuscular injection can be of slow onset, the operation should be delayed if an anaphylactic reaction is suspected, even if the symptoms are limited. In addition, anesthesiologists should be prepared for the occurrence of anaphylaxis at any time in the perioperative period.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Hanyang University Hospital, Seoul, Korea.
authors.forename: Kyu Nam
authors.identifier: 0000-0003-2526-8348
authors.initials: KN
authors.lastname: Kim
authors.affiliation: Department of Anesthesiology and Pain Medicine, Hanyang University Hospital, Seoul, Korea.
authors.forename: Dong Won
authors.identifier: 0000-0003-2492-3144
authors.initials: DW
authors.lastname: Kim
authors.affiliation: Department of Anesthesiology and Pain Medicine, Hanyang University Hospital, Seoul, Korea.
authors.forename: Yeong Hun
authors.initials: YH
authors.lastname: Sin
authors.affiliation: Department of Anesthesiology and Pain Medicine, Hanyang University Hospital, Seoul, Korea.
authors.forename: Soo Kyung
authors.initials: SK
authors.lastname: Lee
keywords: Anaphylaxis; Intramuscular injections; Midazolam