title: Stereoselective synthesis of 2,3,4-highly substituted oxetanes by intramolecular C-C bond forming Michael addition.
abstract: Stereoselective synthesis of 2,3,3,4-tetrasubstituted oxetanes via intramolecular allyl or benzyl anion four-membered ring cyclization of vinylogous urethane derivatives is presented. The resulting products featuring a β-pyrrolidinyl ester at C3 were readily transformed into the corresponding 3-α,β-unsaturated ester substituted oxetanes by Cope elimination reactions.
authors.affiliation: Department of Applied Chemistry, National Chiayi University, 300, Syuefu Road, Chiayi City 600, Taiwan. yjli@mail.ncyu.edu.tw and Genomics Research Center, Academia Sinica, 128, Section 2, Academia Road, Taipei 115, Taiwan.
authors.forename: Guo-Ming
authors.initials: GM
authors.lastname: Ho
authors.affiliation: Department of Applied Chemistry, National Chiayi University, 300, Syuefu Road, Chiayi City 600, Taiwan. yjli@mail.ncyu.edu.tw.
authors.forename: Yu-Jang
authors.identifier: http://orcid.org/0000-0002-6136-687X
authors.initials: YJ
authors.lastname: Li