title: First case of chromoblastomycosis due to Phoma insulana.
abstract: Chromoblastomycosis is a chronic infection, caused by pigmented fungi affecting skin and subcutaneous tissues characterized by verrucous nodules or plaques. Fonsecaea pedrosoi and Cladophialophora carrionii are the prevalent agents in the endemic areas. Phoma is an uncommon agent of human infection and involved mainly with phaeohyphomycosis cases. The case of a patient with a history of laceration in foot followed by verrucous aspect and scaly lesions, which had evolved for 27 years is presented. On physical examination disease was clinically compatible with chromoblastomycosis and the microscopic examination of scales showed fumagoid cells. On culture a dematiaceous fungus was grown. The agent was confirmed to be Phoma insulana based on its morphology and PCR-sequencing. This fungal agent has not been previously reported in association with this pathology.
authors.affiliation: Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, D.F., Mexico. Electronic address: frank-hh@comunidad.unam.mx.
authors.forename: Francisca
authors.initials: F
authors.lastname: Hernández-Hernández
authors.affiliation: Facultad de Ciencias Químicas, Universidad Autónoma «Benito Juárez», Oaxaca, Mexico.
authors.forename: Jaime
authors.initials: J
authors.lastname: Vargas-Arzola
authors.affiliation: Facultad de Ciencias Químicas, Universidad Autónoma «Benito Juárez», Oaxaca, Mexico.
authors.forename: Oliver Pedro
authors.initials: OP
authors.lastname: Ríos-Cruz
authors.affiliation: Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, D.F., Mexico.
authors.forename: Erika
authors.initials: E
authors.lastname: Córdova-Martínez
authors.affiliation: Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, D.F., Mexico.
authors.forename: Patricia
authors.initials: P
authors.lastname: Manzano-Gayosso
authors.affiliation: Facultad de Ciencias Químicas, Universidad Autónoma «Benito Juárez», Oaxaca, Mexico.
authors.forename: Aristeo
authors.initials: A
authors.lastname: Segura-Salvador
mesh_terms: D000368:Aged; D001203:Ascomycota / Q000302:isolation & purification* / Q000472:pathogenicity; D002862:Chromoblastomycosis / Q000209:etiology / Q000382:microbiology*; D017809:Fatal Outcome; D018409:Foot Injuries / Q000150:complications / Q000382:microbiology*; D006801:Humans; D022125:Lacerations / Q000150:complications / Q000382:microbiology; D007871:Leg Ulcer / Q000150:complications / Q000469:parasitology; D008297:Male; D009198:Myiasis / Q000150:complications; D012775:Shoes / Q000009:adverse effects; D013997:Time Factors; D016312:Treatment Refusal; D014946:Wound Infection / Q000209:etiology / Q000382:microbiology*
keywords: Chromoblastomycosis; Chromomycosis; Cromoblastomicosis; Cromomicosis; Micosis subcutáneas; Phoma insulana; Phoma spp.; Subcutaneous mycosis