title: A multidisciplinary approach to giant soft tissue sarcoma of the chest wall: A case report.
abstract: BACKGROUND
  Soft tissue sarcomas of the chest wall are exceptionally rare entities that present as painless slow growing masses. Resection is often precarious due to involvement of vital structures, and patients are left with large chest wall defects postoperatively requiring extensive reconstruction.
  
  
  METHODS
  We present a case report of a 29 year-old man who presented with a giant soft tissue sarcoma of the chest that had been growing slowly for one year prior to presentation. The patient had a biopsy that was positive for sarcoma, and PET CT demonstrated a large lobulated mass in the left chest wall with an SUV of 6.7. He received 50Gy of radiation therapy; however, the mass continued to grow in size. He subsequently underwent an en-bloc resection of the mass with latissimus and serratus muscle primary reconstruction. Final pathology showed a 27cm high-grade fibrosarcoma with prominent myxoid component. To our knowledge, this is the largest soft tissue sarcoma of the chest wall reported in the literature. Postoperatively, the patient received 6 cycles of adjuvant chemotherapy.
  
  
  CONCLUSIONS
  Surgery is the mainstay of treatment, and chemotherapy and radiation are used in specific circumstances. Risk of recurrence is dependent on many factors, including histologic subtype, grade, and size of tumor. Long term surveillance with physical exam and imaging is recommended.
  
  
  CONCLUSIONS
  We feel that the multidisciplinary approach is crucial for optimal management of large soft tissue sarcomas. We recommend this approach to all patients with chest wall sarcomas.
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX, United States.
authors.forename: Catherine H
authors.initials: CH
authors.lastname: Davis
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX, United States.
authors.forename: Halim
authors.initials: H
authors.lastname: Yammine
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX, United States; Weill Cornell Medical College, Houston Methodist Hospital, Houston, TX, United States.
authors.forename: Puja G
authors.initials: PG
authors.lastname: Khaitan
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX, United States.
authors.forename: Edward Y
authors.initials: EY
authors.lastname: Chan
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX, United States; Weill Cornell Medical College, Houston Methodist Hospital, Houston, TX, United States. Electronic address: mpkim@houstonmethodist.org.
authors.forename: Min P
authors.initials: MP
authors.lastname: Kim
keywords: Case report; Chest wall tumor; Soft tissue sarcoma; Thoracic surgery