title: Obstetrical management of patients with extra-anatomic vascular bypass grafts due to Takayasu arteritis.
abstract: Little is known about the obstetrical management of patients with Takayasu arteritis (TA) who have undergone extra-anatomic vascular bypass (EAVB). We describe two cases of EAVB. Case 1 underwent EAVB due to renovascular hypertension associated with stenosis of the abdominal aorta, and Case 2 due to amaurosis fugax episodes associated with stenosis of the brachiocephalic and left common carotid arteries. Pregnancy outcomes were favorable for both cases, though the original symptoms recurred during the third trimester in each case, possibly due to increased blood flow to the pregnant uterus. Neither bypass occlusion nor anastomotic aneurysm formation was observed. Pregnancy outcomes of patients with EAVB due to TA are favorable, although pregnancies of patients with TA who have cardiovascular complications are associated with an increased risk of maternal and fetal morbidity. The obstetrical management of these patients, however, should include monitoring for complications related to the EAVB.
authors.affiliation: Department of Perinatal and Women's Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Miyasaka
authors.affiliation: Department of Perinatal and Women's Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Makiko
authors.identifier: http://orcid.org/0000-0002-1609-1360
authors.initials: M
authors.lastname: Egawa
authors.affiliation: Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Isobe
authors.affiliation: Department of Vascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Inoue
authors.affiliation: Department of Perinatal and Women's Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Toshiro
authors.initials: T
authors.lastname: Kubota
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006973:Hypertension / Q000517:prevention & control; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology* / Q000517:prevention & control / Q000601:surgery; D011256:Pregnancy Outcome; D013625:Takayasu Arteritis / Q000150:complications* / Q000601:surgery*; D014656:Vascular Surgical Procedures; D055815:Young Adult
keywords: Takayasu disease; anticoagulation; complications; extra-anatomic bypass graft; pregnancy