title: Ocular Manifestations, Conventional Fundus Fluorescein Angiographic Findings, and Relationship Between Angiographic Findings and Visual Acuity in Behçet's Disease.
abstract: OBJECTIVE
  Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behçet's disease as well as the relationship between visual acuity and angiographic findings.
  
  
  METHODS
  Retrospective chart review of patients with Behçet's disease seen at the Farabi Eye Hospital.
  
  
  RESULTS
  Forty-six patients (92 eyes) with mean age of 33.41 ± 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively. Panuveitis was the most frequent type of uveitis (76%). Among patients with FA, vasculitis was the most common finding (87%) and it was significantly more severe among patients with visual acuity less than 20/200. Macular leakage (P = 0.001), arterial narrowing (P = 0.000), and posterior retinal vasculitis (P = 0.002) on FA were all associated with worsening final visual acuity.
  
  
  CONCLUSIONS
  The most common ocular findings in Behçet's disease were panuveitis and vasculitis. Location of vasculitis, arterial narrowing, and macular leakage on initial FA may predict visual prognosis.
authors.affiliation: a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Bazvand
authors.affiliation: a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zarei
authors.affiliation: b Retina Service, Department of Ophthalmology , Massachusetts Eye and Ear Infirmary, Harvard Medical School , Boston , MA , USA.
authors.forename: Nazanin
authors.initials: N
authors.lastname: Ebrahimiadib
authors.affiliation: a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Karkhaneh
authors.affiliation: b Retina Service, Department of Ophthalmology , Massachusetts Eye and Ear Infirmary, Harvard Medical School , Boston , MA , USA.
authors.forename: Samaneh
authors.initials: S
authors.lastname: Davoudi
authors.affiliation: a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Mahyar
authors.initials: M
authors.lastname: Soleimanzadeh
authors.affiliation: a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Elaheh
authors.initials: E
authors.lastname: Sharifian
authors.affiliation: a Eye Research Center, Farabi Eye Hospital , Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Ramak
authors.initials: R
authors.lastname: Roohipoor
authors.affiliation: b Retina Service, Department of Ophthalmology , Massachusetts Eye and Ear Infirmary, Harvard Medical School , Boston , MA , USA.
authors.forename: Bobeck S
authors.initials: BS
authors.lastname: Modjtahedi
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D005128:Eye Diseases / Q000209:etiology / Q000503:physiopathology; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000503:physiopathology; D031300:Retinal Vasculitis / Q000503:physiopathology; D012189:Retrospective Studies; D014605:Uveitis / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult
keywords: Autoimmune disease; macular edema; papillitis; uveitis; vasculitis