title: Approach Based on Polyelectrolyte-Induced Nanoassemblies for Enhancing Sensitivity of Pyrenyl Probes.
abstract: We have developed a unique approach for enhancing the sensitivity of pyrenyl probes based on polyelectrolyte-induced nanoassemblies and explored its sensing application toward 2,4,6-trinitrophenol (TNP). The key issue of the method is the formation of the nanoassemblies which possess high-density charges, specific surface area, and inner hydrophobic regions. These properties would help increase the loading of analytes and promote probe-analyte interactions, thereby leading to the prominent enhancement of the sensitivity. In the course of TNP detection, pyrene nanoassemblies can bind TNP efficiently through cooperative noncovalent interactions including electrostatic, π-π stacking, and charge-transfer interactions, resulting in the distinct fluorescent responses of pyrene moieties. This system has excellent selectivity and sensitivity for TNP detection. The detection limit is as low as 5 nM. It may be used for monitoring the TNP concentrations in real-world samples.
authors.affiliation: Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences , Beijing 100049, China.
authors.forename: Zhiyi
authors.initials: Z
authors.lastname: Yao
authors.affiliation: School of Materials Science and Engineering, Zhengzhou University , Zhengzhou 450052, China.
authors.forename: Yadong
authors.initials: Y
authors.lastname: Qiao
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology , Changsha 410114, China.
authors.forename: Haiqin
authors.initials: H
authors.lastname: Liang
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology , Changsha 410114, China.
authors.forename: Wenqi
authors.initials: W
authors.lastname: Ge
authors.affiliation: School of Materials Science and Engineering, Zhengzhou University , Zhengzhou 450052, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology , Changsha 410114, China.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Cao
authors.affiliation: Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences , Beijing 100049, China.
authors.forename: Hai-Chen
authors.initials: HC
authors.lastname: Wu