title: A New Role for Lyn in the CLL Microenvironment.
abstract: The role of Lyn, both a positive and a negative regulator of B and myeloid cells, in chronic lymphocytic leukemia (CLL) has not been well characterized. In this issue of Cancer Cell, Nguyen et al. demonstrated that Lyn in macrophages rather than in CLL cells is critical for the malignancy.
authors.affiliation: Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Shuai
authors.initials: S
authors.lastname: Dong
authors.affiliation: Division of Hematology, Department of Internal Medicine and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. Electronic address: john.byrd@osumc.edu.
authors.forename: John C
authors.initials: JC
authors.lastname: Byrd
mesh_terms: D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell; D008264:Macrophages; D022423:Myeloid Cells; D019061:src-Family Kinases
chemical_list: D019061:src-Family Kinases