title: Asynchronous division by non-ring FtsZ in the gammaproteobacterial symbiont of Robbea hypermnestra.
abstract: The reproduction mode of uncultivable microorganisms deserves investigation as it can largely diverge from conventional transverse binary fission. Here, we show that the rod-shaped gammaproteobacterium thriving on the surface of the Robbea hypermnestra nematode divides by FtsZ-based, non-synchronous invagination of its poles-that is, the host-attached and fimbriae-rich pole invaginates earlier than the distal one. We conclude that, in a naturally occurring animal symbiont, binary fission is host-oriented and does not require native FtsZ to polymerize into a ring at any septation stage.
authors.affiliation: Department of Ecogenomics and Systems Biology, Archaeal Biology and Ecogenomics Division, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.|Max Planck Institute for Marine Microbiology, Celsiusstrasse 1, D-28359 Bremen, Germany.
authors.forename: Nikolaus
authors.identifier: http://orcid.org/0000-0001-7375-3749
authors.initials: N
authors.lastname: Leisch
authors.affiliation: Department of Ecogenomics and Systems Biology, Archaeal Biology and Ecogenomics Division, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
authors.forename: Nika
authors.initials: N
authors.lastname: Pende
authors.affiliation: Department of Ecogenomics and Systems Biology, Archaeal Biology and Ecogenomics Division, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
authors.forename: Philipp M
authors.initials: PM
authors.lastname: Weber
authors.affiliation: Max Planck Institute for Marine Microbiology, Celsiusstrasse 1, D-28359 Bremen, Germany.
authors.forename: Harald R
authors.initials: HR
authors.lastname: Gruber-Vodicka
authors.affiliation: Bacterial Cell Biology, Swammerdam Institute of Life Sciences, Faculty of Science, University of Amsterdam, Boelelaan 1108, 1081 HZ Amsterdam, Netherlands.
authors.forename: Jolanda
authors.initials: J
authors.lastname: Verheul
authors.affiliation: Bacterial Cell Biology, Swammerdam Institute of Life Sciences, Faculty of Science, University of Amsterdam, Boelelaan 1108, 1081 HZ Amsterdam, Netherlands.
authors.forename: Norbert O E
authors.initials: NO
authors.lastname: Vischer
authors.affiliation: Department of Ecogenomics and Systems Biology, Archaeal Biology and Ecogenomics Division, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
authors.forename: Sophie S
authors.initials: SS
authors.lastname: Abby
authors.affiliation: Max Planck Institute for Marine Microbiology, Celsiusstrasse 1, D-28359 Bremen, Germany.
authors.forename: Benedikt
authors.initials: B
authors.lastname: Geier
authors.affiliation: Bacterial Cell Biology, Swammerdam Institute of Life Sciences, Faculty of Science, University of Amsterdam, Boelelaan 1108, 1081 HZ Amsterdam, Netherlands.
authors.forename: Tanneke
authors.initials: T
authors.lastname: den Blaauwen
authors.affiliation: Department of Ecogenomics and Systems Biology, Archaeal Biology and Ecogenomics Division, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
authors.forename: Silvia
authors.initials: S
authors.lastname: Bulgheresi
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism*; D002455:Cell Division; D000073560:Chromadorea / Q000382:microbiology; D003598:Cytoskeletal Proteins / Q000378:metabolism*; D020563:Gammaproteobacteria / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*
chemical_list: D001426:Bacterial Proteins; D003598:Cytoskeletal Proteins; C071525:FtsZ protein, Bacteria