title: DNA-templated silver nanoclusters: structural correlation and fluorescence modulation.
abstract: 12 years after the introduction of DNA-templated silver nanoclusters (DNA-AgNCs), exciting progress has been made and yet we are still in the midst of trying to fully understand this nanomaterial. The prominent excellence of DNA-AgNCs is undoubtedly its modulatable emission property, of which how variation in DNA templates causes emission tuning remains elusive. Based on the up-to-date DNA-AgNCs, we aim to establish the correlation between the structure/sequence of DNA templates and emission behaviour of AgNCs. Herein, we systematically present a wide-range of DNA-AgNCs based on the structural complexity of the DNA templates, including single-stranded DNA (ssDNA), double-stranded DNA (dsDNA), triple-stranded DNA (tsDNA) and DNA nanostructures. For each DNA category, we discuss the emission property, quantum yield and synthesis condition of the respective AgNCs, before cross-comparing the impact of different DNA scaffolds on the properties of AgNCs. A future outlook for this area is given as a conclusion. By putting the information together, this review may shed new light on understanding DNA-AgNCs while we are expecting continuous breakthroughs in this field.
authors.affiliation: School of Pharmacy, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia. SiuYee.New@nottingham.edu.my.
authors.forename: S Y
authors.identifier: http://orcid.org/0000-0003-4392-3852
authors.initials: SY
authors.lastname: New
authors.affiliation: School of Pharmacy, Faculty of Science, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia. SiuYee.New@nottingham.edu.my.
authors.forename: S T
authors.initials: ST
authors.lastname: Lee
authors.affiliation: Institute of Materials Research and Engineering, 2 Fusionopolis Way, Singapore 138634. xd-su@imre.a-star.edu.sg.
authors.forename: X D
authors.initials: XD
authors.lastname: Su
mesh_terms: D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D053768:Metal Nanoparticles; D009690:Nucleic Acid Conformation; D012834:Silver; D013050:Spectrometry, Fluorescence
chemical_list: D004277:DNA, Single-Stranded; D012834:Silver; D004247:DNA