title: Design of multichannel functional near-infrared spectroscopy system with application to propofol and sevoflurane anesthesia monitoring.
abstract: Monitoring the changes of cerebral hemodynamics and the state of consciousness during general anesthesia (GA) is clinically important. There is a great need for developing advanced detectors to investigate the physiological processes of the brain during GA. We developed a multichanneled, functional near-infrared spectroscopy (fNIRS) system device and applied it to GA operation monitoring. The cerebral hemodynamic data from the forehead of 11 patients undergoing propofol and sevoflurane anesthesia were analyzed. The concentration changes of oxygenated hemoglobin, deoxygenated hemoglobin, total hemoglobin, and cerebral tissue heart rate were determined from the raw optical information based on the discrete stationary wavelet transform. This custom-made device provides an easy-to-build solution for continuous wave-fNIRS system, with customized specifications. The developed device has a potential value in cerebral monitoring in clinical settings.
authors.affiliation: Yanshan University , Institute of Electrical Engineering, No. 438 Hebei Street, Haigang District, Qinhuangdao 066004, China.
authors.forename: Zhenhu
authors.initials: Z
authors.lastname: Liang
authors.affiliation: Yanshan University , Institute of Electrical Engineering, No. 438 Hebei Street, Haigang District, Qinhuangdao 066004, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Gu
authors.affiliation: Yanshan University , Institute of Electrical Engineering, No. 438 Hebei Street, Haigang District, Qinhuangdao 066004, China.
authors.forename: Xuejing
authors.initials: X
authors.lastname: Duan
authors.affiliation: Yanshan University , Institute of Electrical Engineering, No. 438 Hebei Street, Haigang District, Qinhuangdao 066004, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Cheng
authors.affiliation: Department of Anesthesia , No. 1 Hospital of Qinhuangdao, No. 258 Wenhua Street, Haigang District, Qinhuangdao 066004, China.
authors.forename: Shujuan
authors.initials: S
authors.lastname: Liang
authors.affiliation: McLean Hospital , McLean Imaging Center, 115 Mill Street, Belmont, Massachusetts 02478, United States.
authors.forename: Yunjie
authors.initials: Y
authors.lastname: Tong
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, No. 19 Xinjiekou Wai Street, Haidian District, Beijing 100875, China; Beijing Normal University, Center for Collaboration and Innovation in Brain and Learning Sciences, No. 19 Xinjiekou Wai Street, Haidian District, Beijing 100875, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Li
keywords: cerebral hemodynamic; discrete stationary wavelet transform; functional near-infrared spectroscopy; general anesthesia