title: Report - Antibacterial activity of sea buckthorn (Hippophae rhamnoides L.) against methicillin resistant Staphylococcus aureus (MRSA).
abstract: Objective of the present study was to investigate the antibacterial activity of Sea buckthorn (Hippophae rhamnoides L.) berries and leaves against methicillin resistant Staphylococcus aureus (MRSA) by using the standard disc diffusion method. Chloroform, n-hexane and aqueous extract of the plant parts were used. Doses of 2mg/ml, 4 mg/ml and 6mg/ml were tested against the microorganism, and the zone of inhibition was compared against the standard drug vancomycin. Results indicated that n-hexane and chloroform extracts of berries and n-hexane extract leaves showed significant (p<0.05) antibacterial activity comparable with vancomycin. It was concluded from the study that extracts berries and leaves of Hippophae rhamnoides have antibacterial activity against MRSA.
authors.affiliation: Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan, Pakistan / Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
authors.forename: Muhammad Imran
authors.initials: MI
authors.lastname: Qadir
authors.affiliation: Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
authors.forename: Khizar
authors.initials: K
authors.lastname: Abbas
authors.affiliation: Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
authors.forename: Adnan
authors.initials: A
authors.lastname: Younus
authors.affiliation: Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.
authors.forename: Rehan Sadiq
authors.initials: RS
authors.lastname: Shaikh
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D052978:Disk Diffusion Antimicrobial Tests; D005638:Fruit; D031281:Hippophae / Q000737:chemistry; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves; D010946:Plants, Medicinal; D012997:Solvents / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D012997:Solvents