title: Metastasis in Adult Brain Tumors.
abstract: Metastatic cancer to the central nervous system is primarily deposited by hematogenous spread in various anatomically distinct regions: calvarial, pachymeningeal, leptomeningeal, and brain parenchyma. A patient's overall clinical status and the information needed to make treatment decisions are the primary considerations in initial imaging modality selection. Contrast-enhanced MR imaging is the preferred imaging modality. Morphologic MR imaging is limited to delineating anatomic deraignment of tissues. Dynamic susceptibility contrast-enhanced perfusion and diffusion-weighted physiology-based MR imaging sequences have been developed that complement morphologic MR imaging by providing additional diagnostic information.
authors.affiliation: Departments of Radiology and Advanced Imaging Research Center, Oregon Health and Science University, 3181 South West Sam Jackson Park Road, Portland, OR 97239, USA.
authors.forename: Ramon Francisco
authors.initials: RF
authors.lastname: Barajas
authors.affiliation: Departments of Neurological Surgery, Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Avenue, Long L200B, Box 0628, San Francisco, CA 94143, USA. Electronic address: soonmee.cha@ucsf.edu.
authors.forename: Soonmee
authors.initials: S
authors.lastname: Cha
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D003287:Contrast Media; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging; D059906:Neuroimaging / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media
keywords: Brain; DSC perfusion; MR Imaging; Metastasis