title: Biomonitoring and exposure assessment of people living near or working at an Italian waste incinerator: methodology of the SPoTT study.
abstract: Only few studies on the health effect of waste incinerators were focused on human biomonitoring (HBM). Our aim is to describe a protocol for assessing early variation of selected items in a population group living close to a waste incinerator in Turin, Italy. A cohort of 394 subjects was randomly selected, among residents near the incinerator and residents far from it. To achieve this sample size, 765 subjects were contacted. The cohort was monitored before the start-up of the plant and will be followed up 1 and 3 years after, with measurements of respiratory function, selected blood and urine parameters including 19 metals, 17 congeners of PCDDs/Fs, 12 congeners of DL-PCBs, 30 congeners of NDL-PCBs, 11 OH-PAHs, specific hormones (T3, T4, TSH, cortisol and ACTH) and common health parameters. The same protocol is applied for plant workers and breeders living near the plant. Individual exposure to urban pollution and waste incinerator fallout were assessed through the use of mathematical models. Information on individual habits was assessed using a specific questionnaire. SPoTT is the first Italian study that adopts a longitudinal design of appropriate statistical power to assess health impacts of waste incinerator plants' emission. The initial results comparing the baseline to the first follow-up are due at the end of 2016.
authors.affiliation: Department of Epidemiology, ASL TO3, Via Sabaudia 164, 10095, Grugliasco, TO, Italy. antonella.bena@epi.piemonte.it.
authors.forename: Antonella
authors.initials: A
authors.lastname: Bena
authors.affiliation: Department of Epidemiology, ASL TO3, Via Sabaudia 164, 10095, Grugliasco, TO, Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Orengia
authors.affiliation: Department of Epidemiology and Environmental Health, Regional Environmental Protection Agency, Via Pio VII 9, Turin, Italy.
authors.forename: Ennio
authors.initials: E
authors.lastname: Cadum
authors.affiliation: Department of Epidemiology, ASL TO3, Via Sabaudia 164, 10095, Grugliasco, TO, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Farina
authors.affiliation: Department of Environment and Health, Italian National Institute of Health, Viale Regina Elena, 299, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Alimonti
authors.affiliation: Department of Environment and Health, Italian National Institute of Health, Viale Regina Elena, 299, Rome, Italy.
authors.forename: Beatrice
authors.initials: B
authors.lastname: Bocca
authors.affiliation: Department of Epidemiology and Environmental Health, Regional Environmental Protection Agency, Via Pio VII 9, Turin, Italy.
authors.forename: Monica
authors.initials: M
authors.lastname: Chiusolo
authors.affiliation: Department of the Environment and Primary Prevention, Italian National Institute of Health, Viale Regina Elena, 299, Rome, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: De Felip
authors.affiliation: Department of Epidemiology and Environmental Health, Regional Environmental Protection Agency, Via Pio VII 9, Turin, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Gandini
authors.affiliation: Department of the Environment and Primary Prevention, Italian National Institute of Health, Viale Regina Elena, 299, Rome, Italy.
authors.forename: Anna Laura
authors.initials: AL
authors.lastname: Iamiceli
authors.affiliation: Department of Environment and Health, Italian National Institute of Health, Viale Regina Elena, 299, Rome, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Pino
authors.affiliation: Department of Prevention, ASL TO3, Piazza San Francesco 4, Susa, Turin, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Procopio
authors.affiliation: Department of Prevention, ASL TO1, Via della Consolata 10, Turin, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Salamina
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods*; D005260:Female; D006801:Humans; D017745:Incineration; D007558:Italy; D008297:Male; D008670:Metals / Q000032:analysis* / Q000097:blood / Q000652:urine; D008875:Middle Aged; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000097:blood / Q000652:urine; D000072317:Polychlorinated Dibenzodioxins / Q000032:analysis* / Q000097:blood / Q000652:urine; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*
chemical_list: D008670:Metals; D000072317:Polychlorinated Dibenzodioxins; D011084:Polycyclic Aromatic Hydrocarbons; D011078:Polychlorinated Biphenyls
keywords: Biomonitoring; Metals; PAH; PCDD/F; Waste incinerator