title: Clinical features and psychiatric comorbidities of borderline personality disorder patients with versus without a history of suicide attempt.
abstract: Patients with borderline personality disorder (BPD) are at high risk for suicidal behavior. However, many BPD patients do not engage in suicidal behavior. In this study, we compared clinical features of BPD patients with or without a history of suicide attempts and healthy volunteers. Compared with healthy volunteers, both BPD groups had higher Affective Lability Scale (ALS), ALS - Depression-Anxiety Subscale, Barratt Impulsivity Scale (BIS), and Lifetime History of Aggression (LHA) scores and were more likely to have a history of temper tantrums. BPD suicide attempters had higher ALS, ALS - Depression-Anxiety Subscale and LHA scores and were more likely to have a history of non-suicidal self-injury or temper tantrums compared to BPD non-attempters. Also, BPD suicide attempters were more likely to have a history of comorbid major depressive disorder and less likely to have comorbid narcissistic personality disorder (NPD) in comparison to BPD non-attempters. About 50% of study participants in each BPD group had a history of comorbid substance use disorder (SUD). Our study indicates that BPD patients with a history of suicide attempt are more aggressive, affectively dysregulated and less narcissistic than BPD suicide non-attempters.
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Inpatient and Outpatient Psychiatry, James J. Peters VA Medical Center, Bronx, NY, United States. Electronic address: leo.sher@mssm.edu.
authors.forename: Leo
authors.initials: L
authors.lastname: Sher
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Amanda M
authors.initials: AM
authors.lastname: Fisher
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Caitlin H
authors.initials: CH
authors.lastname: Kelliher
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Inpatient and Outpatient Psychiatry, James J. Peters VA Medical Center, Bronx, NY, United States; Mental Illness Research, Education, and Clinical Center (MIRECC; VISN 2 South), James J. Peters VA Medical Center, Bronx, NY, United States.
authors.forename: Justin D
authors.initials: JD
authors.lastname: Penner
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Inpatient and Outpatient Psychiatry, James J. Peters VA Medical Center, Bronx, NY, United States; Mental Illness Research, Education, and Clinical Center (MIRECC; VISN 2 South), James J. Peters VA Medical Center, Bronx, NY, United States.
authors.forename: Marianne
authors.initials: M
authors.lastname: Goodman
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Inpatient and Outpatient Psychiatry, James J. Peters VA Medical Center, Bronx, NY, United States.
authors.forename: Harold W
authors.initials: HW
authors.lastname: Koenigsberg
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
authors.forename: Antonia S
authors.initials: AS
authors.lastname: New
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Inpatient and Outpatient Psychiatry, James J. Peters VA Medical Center, Bronx, NY, United States; Mental Illness Research, Education, and Clinical Center (MIRECC; VISN 2 South), James J. Peters VA Medical Center, Bronx, NY, United States.
authors.forename: Larry J
authors.initials: LJ
authors.lastname: Siever
authors.affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Mental Illness Research, Education, and Clinical Center (MIRECC; VISN 2 South), James J. Peters VA Medical Center, Bronx, NY, United States.
authors.forename: Erin A
authors.initials: EA
authors.lastname: Hazlett
mesh_terms: D000328:Adult; D001883:Borderline Personality Disorder / Q000453:epidemiology / Q000503:physiopathology*; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000503:physiopathology*; D013406:Suicide, Attempted / Q000523:psychology* / Q000706:statistics & numerical data; D055815:Young Adult
keywords: Affective lability; Borderline personality disorder; Depression; Narcissistic personality disorder; Suicide