title: AP736 induces miR-125b expression for the efficient whitening and anti-ageing action in human epidermal cells.
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.|Department of Bionano Technology, Hanyang University, Ansan-si, Republic of Korea.
authors.forename: Heung Soo
authors.initials: HS
authors.lastname: Baek
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Jung-Ah
authors.initials: JA
authors.lastname: Hwang
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Il-Hong
authors.initials: IH
authors.lastname: Bae
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Kyu-Han
authors.initials: KH
authors.lastname: Kim
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Yung Hyup
authors.initials: YH
authors.lastname: Joo
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Yong Jin
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Hong-Ju
authors.initials: HJ
authors.lastname: Shin
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: John Hwan
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Young-Ho
authors.initials: YH
authors.lastname: Park
authors.affiliation: Department of Applied Chemistry, Hanyang University, Ansan-si, Republic of Korea.|Department of Bionano Technology, Hanyang University, Ansan-si, Republic of Korea.
authors.forename: Jin Woong
authors.initials: JW
authors.lastname: Kim
authors.affiliation: Amorepacific CO R&D Center, Yongin-si, Republic of Korea.
authors.forename: Chang Seok
authors.initials: CS
authors.lastname: Lee
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives* / Q000494:pharmacology; D001549:Benzamides / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D006801:Humans; D015603:Keratinocytes / Q000187:drug effects / Q000378:metabolism; D020782:Matrix Metalloproteinases / Q000378:metabolism; D008543:Melanins / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D008544:Melanocytes / Q000187:drug effects* / Q000378:metabolism; D035683:MicroRNAs / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism; D015595:Skin Aging / Q000187:drug effects; D062327:Skin Lightening Preparations / Q000494:pharmacology*
chemical_list: C000592311:5-adamantan-1-yl-N-(2,4-dihydroxybenzyl)-2,4-dimethoxybenzamide; D001549:Benzamides; C531888:MIRN125 microRNA, human; D008543:Melanins; D035683:MicroRNAs; D017382:Reactive Oxygen Species; D062327:Skin Lightening Preparations; D020782:Matrix Metalloproteinases; D000218:Adamantane