title: Antibacterial effect of chlorhexidine-cetrimide combination, Salvia officinalis plant extract and octenidine in comparison with conventional endodontic irrigants.
abstract: The aim of the present study was to compare the antimicrobial effect of sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), a CHX/cetrimide solution (CHX+CTR), octenidine hydrochloride (OCT) and Salvia officinalis plant extract against Enterococcus faecalis. Seventy decoronated single-rooted human teeth were infected and divided into 6 test (n=10) and 2 control groups (n=5) (negative, sterile samples and positive, infected samples). Following irrigants were then applied to test groups: 2.5% NaOCl, 5.25% NaOCl, CHX, CHX+CTR, S. officinalis extract and OCT. The dentin chips were obtained from inner root canal walls and analyzed by counting the number of colony forming units (CFU). The 2.5% NaOCl, 5.25% NaOCl, CHX and OCT groups presented no bacterial growth (CFU=0). S. officinalis and CHX+CTR groups reduced the number of E. faecalis cells but could not eliminate all. OCT may have potential as an endodontic irrigant in treatment of infected root canals.
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Bezmialem Vakif University.
authors.forename: Mehmet Burak
authors.initials: MB
authors.lastname: Guneser
authors.forename: Makbule Bilge
authors.initials: MB
authors.lastname: Akbulut
authors.forename: Ayce Unverdi
authors.initials: AU
authors.lastname: Eldeniz
mesh_terms: D000900:Anti-Bacterial Agents; D002593:Cetrimonium Compounds; D002710:Chlorhexidine; D003786:Dental Pulp Cavity; D013293:Enterococcus faecalis; D006801:Humans; D010936:Plant Extracts; D012388:Root Canal Irrigants; D027543:Salvia officinalis; D012973:Sodium Hypochlorite
chemical_list: D000900:Anti-Bacterial Agents; D002593:Cetrimonium Compounds; D010936:Plant Extracts; D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite; D002710:Chlorhexidine