title: The inositols and polycystic ovary syndrome.
abstract: This review describes the rationale, biochemical, and clinical data related to the use of inositols in polycystic ovary syndrome (PCOS). It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol (MDI), with randomized controlled trials conducted in women with PCOS, and utilizes these data to suggest pragmatic indications and methods for using MDI combination in PCOS. Rationally crafted inositol combinations have a potential role to play in maintaining metabolic, endocrine, and reproductive health in women with PCOS.
authors.affiliation: Department of Obstetrics, Bharti Hospital, Karnal, Haryana, India.
authors.forename: Bharti
authors.initials: B
authors.lastname: Kalra
authors.affiliation: Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kalra
authors.affiliation: Department of Obstetrics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: J B
authors.initials: JB
authors.lastname: Sharma
keywords: D-chiro-inositol; diabetes; infertility; metabolic syndrome; myo-inositol; ovarian paradox; ovulation; polycystic ovary syndrome