title: Neoplasia in 125 donkeys (Equus asinus): literature review and a survey of five veterinary schools in the United States and Canada.
abstract: A diagnosis of neoplasia was noted in 125 of 357 donkeys (35%) in our review of medical records from 5 veterinary schools in the United States and Canada. Equine sarcoid was the most common tumor in our study, accounting for 72% of all tumors and 82% of cutaneous tumors. Soft-tissue sarcomas were the second most common skin tumors. All other types of neoplasia were rare. Important differences in the occurrence of neoplasia in donkeys compared to horses included the rarity or absence of squamous cell carcinoma in any organ system and gray horse melanoma. Lymphosarcoma, the most common malignant tumor in horses, appears to be very rare in donkeys. We report several tumors in donkeys including melanocytoma, peripheral nerve sheath tumor, and gastrointestinal stromal tumor. Our data demonstrate commonalities as well as differences in neoplastic diseases of donkeys and horses. Understanding differences in carcinogenesis among these 2 closely related species can inform researchers pursuing pathogenic mechanisms of equine disease and inform veterinary diagnosticians regarding tumor prevalence.
authors.affiliation: Private pathology practice, Maupin, OR (Davis)College of Veterinary Medicine, Oregon State University, Corvallis, OR (Valentine, Gordon)College of Veterinary Medicine, Cornell University, Ithaca, NY (McDonough)Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO (Schaffer)Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Allen)Department of Pathology, Microbiology & Immunology, University of California-Davis, Davis, CA (Pesavento) cdavis.pathology@yahoo.com.
authors.forename: Corrine R
authors.initials: CR
authors.lastname: Davis
authors.affiliation: Private pathology practice, Maupin, OR (Davis)College of Veterinary Medicine, Oregon State University, Corvallis, OR (Valentine, Gordon)College of Veterinary Medicine, Cornell University, Ithaca, NY (McDonough)Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO (Schaffer)Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Allen)Department of Pathology, Microbiology & Immunology, University of California-Davis, Davis, CA (Pesavento).
authors.forename: Beth A
authors.initials: BA
authors.lastname: Valentine
authors.affiliation: Private pathology practice, Maupin, OR (Davis)College of Veterinary Medicine, Oregon State University, Corvallis, OR (Valentine, Gordon)College of Veterinary Medicine, Cornell University, Ithaca, NY (McDonough)Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO (Schaffer)Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Allen)Department of Pathology, Microbiology & Immunology, University of California-Davis, Davis, CA (Pesavento).
authors.forename: Emma
authors.initials: E
authors.lastname: Gordon
authors.affiliation: Private pathology practice, Maupin, OR (Davis)College of Veterinary Medicine, Oregon State University, Corvallis, OR (Valentine, Gordon)College of Veterinary Medicine, Cornell University, Ithaca, NY (McDonough)Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO (Schaffer)Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Allen)Department of Pathology, Microbiology & Immunology, University of California-Davis, Davis, CA (Pesavento).
authors.forename: Sean P
authors.initials: SP
authors.lastname: McDonough
authors.affiliation: Private pathology practice, Maupin, OR (Davis)College of Veterinary Medicine, Oregon State University, Corvallis, OR (Valentine, Gordon)College of Veterinary Medicine, Cornell University, Ithaca, NY (McDonough)Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO (Schaffer)Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Allen)Department of Pathology, Microbiology & Immunology, University of California-Davis, Davis, CA (Pesavento).
authors.forename: Paula A
authors.initials: PA
authors.lastname: Schaffer
authors.affiliation: Private pathology practice, Maupin, OR (Davis)College of Veterinary Medicine, Oregon State University, Corvallis, OR (Valentine, Gordon)College of Veterinary Medicine, Cornell University, Ithaca, NY (McDonough)Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO (Schaffer)Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Allen)Department of Pathology, Microbiology & Immunology, University of California-Davis, Davis, CA (Pesavento).
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Allen
authors.affiliation: Private pathology practice, Maupin, OR (Davis)College of Veterinary Medicine, Oregon State University, Corvallis, OR (Valentine, Gordon)College of Veterinary Medicine, Cornell University, Ithaca, NY (McDonough)Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO (Schaffer)Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Allen)Department of Pathology, Microbiology & Immunology, University of California-Davis, Davis, CA (Pesavento).
authors.forename: Patricia
authors.initials: P
authors.lastname: Pesavento
mesh_terms: D000818:Animals; D002170:Canada; D018397:Equidae; D006734:Horse Diseases / Q000145:classification / Q000453:epidemiology* / Q000209:etiology; D006736:Horses; D009369:Neoplasms / Q000145:classification / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*; D015995:Prevalence; D012582:Schools, Veterinary; D011795:Surveys and Questionnaires; D014481:United States
keywords: Ass; Equus asinus; burros; disease; donkeys; equine; neoplasia; review; tumor