title: Nutritional Deficiencies and Sarcopenia in Heart Failure: A Therapeutic Opportunity to Reduce Hospitalization and Death.
abstract: There is an expanding prevalence pool of heart failure (HF) due to the increasing prevalence of survivors of myocardial infarction, diabetes, hypertension, chronic kidney disease, and obesity. There is increasing interest in the role of nutrition in all forms of HF, given observations concerning micro- and macronutrient deficiencies, loss of lean body mass or sarcopenia, and their relationships with hospitalization and death. This review examines the relationships among loss of lean body mass, macro- and micronutrient intake, and the natural history of HF, particularly in the elderly, in whom the risks for all-cause rehospitalization, infection, falls, and mortality are increased. These risks are potentially modifiable through strategies that improve nutrition in this vulnerable population.
authors.affiliation: Baylor University Medical Center, Dallas, TX.|Baylor Heart and Vascular Institute, Dallas, TX.|Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, TX.|The Heart Hospital Baylor Plano, Plano, TX.
authors.forename: Peter A
authors.initials: PA
authors.lastname: McCullough
authors.affiliation: Baylor University Medical Center, Dallas, TX.
authors.forename: Mohammad Kazem
authors.initials: MK
authors.lastname: Fallahzadeh
authors.affiliation: Abbott Nutrition, Inc, Columbus, OH.
authors.forename: Refaat M
authors.initials: RM
authors.lastname: Hegazi
mesh_terms: D000367:Age Factors; D000368:Aged; D001823:Body Composition; D002423:Cause of Death; D005260:Female; D015577:Geriatric Assessment; D006333:Heart Failure / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D006760:Hospitalization; D006801:Humans; D008297:Male; D015596:Nutrition Assessment; D009748:Nutrition Disorders / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D009752:Nutritional Status; D015995:Prevalence; D012307:Risk Factors; D055948:Sarcopenia / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*