title: Advocating for both Environmental and Clinical Approaches to Control Human Strongyloidiasis.
abstract: Strongyloidiasis is an underestimated disease caused by the soil-transmitted parasite of the genusStrongyloides. It is prevalent in socioeconomically disadvantaged communities and it is estimated that global infection could be as high as 370 million people. This paper explores current methods of strongyloidiasis treatment, which rely on administration of anthelminthic drugs. However these drugs cannot prevent reinfection and drug resistance has already been observed in veterinary models. This highlights the need for a combined approach for controllingStrongyloidesthat includes both clinical treatment and environmental control methods. Currently, nematicides are widely used to control plant parasites. The review suggests that due to the species' similarity and similar modes of action, these nematicides could also be used to control animal and human parasitic nematodes in the environment.
authors.affiliation: School of the Environment, Flinders University, GPO Box 2100, Adelaide 5001, Australia. mira.beknazarova@flinders.edu.au.
authors.forename: Meruyert
authors.initials: M
authors.lastname: Beknazarova
authors.affiliation: School of the Environment, Flinders University, GPO Box 2100, Adelaide 5001, Australia. harriet.whiley@flinders.edu.au.
authors.forename: Harriet
authors.initials: H
authors.lastname: Whiley
authors.affiliation: School of the Environment, Flinders University, GPO Box 2100, Adelaide 5001, Australia. kirstin.ross@flinders.edu.au.
authors.forename: Kirstin
authors.initials: K
authors.lastname: Ross
keywords: Strongyloides stercoralis; anthelminthic drugs; ivermectin; nematicides; resistance; strongyloidiasis