title: Delphi consensus on the diagnosis and management of dyslipidaemia in chronic kidney disease patients: A post hoc analysis of the DIANA study.
abstract: OBJECTIVE
  This post hoc study analysed the perception of the relevance of chronic kidney disease (CKD) in dyslipidaemia screening and the choice of statin among primary care physicians (PCPs) and other specialists through a Delphi questionnaire.
  
  
  METHODS
  The questionnaire included 4blocks of questions concerning dyslipidaemic patients with impaired carbohydrate metabolism. This study presents the results of the impact of CKD on screening and the choice of statin.
  
  
  RESULTS
  Of the 497 experts included, 58% were PCPs and 42% were specialists (35, 7% were nephrologists). There was consensus by both PCPs and specialists, with no difference between PCPs and specialists, that CKD patients should undergo a dyslipidaemia screening and that the screening should be part of routine clinical practice. However, there was no consensus in considering the estimated glomerular filtration rate (eGFR) (although there was consensus among PCPs and nephrologists), or considering albuminuria when selecting a statin, or in determining albuminuria during follow-up after having initiated treatment with statins (although there was consensus among the nephrologists).
  
  
  CONCLUSIONS
  The consensus to analyse the lipid profile in CKD patients suggests acknowledgment of the high cardiovascular risk of this condition. However, the lack of consensus in considering renal function or albuminuria, both when selecting a statin and during follow-up, suggests a limited knowledge of the differences between statins in relation to CKD. Thus, it would be advisable to develop a guideline/consensus document on the use of statins in CKD.
authors.affiliation: Servicio de Nefrología, Hospital Clínic, Universitat de Barcelona, Red de Investigación Cardiovascular (RIC), Barcelona, España. Electronic address: acases@clinic.ub.es.
authors.forename: Aleix
authors.initials: A
authors.lastname: Cases Amenós
authors.affiliation: Unidad de Lípidos y Riesgo Vascular, Servicio de Endocrinología y Nutrición, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: Juan
authors.initials: J
authors.lastname: Pedro-Botet Montoya
authors.affiliation: Centro de Salud Palleter, Castellón, España.
authors.forename: Vicente
authors.initials: V
authors.lastname: Pascual Fuster
authors.affiliation: Servicio de Cardiología, Hospital Universitario Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, España.
authors.forename: Vivencio
authors.initials: V
authors.lastname: Barrios Alonso
authors.affiliation: Unidad de Lípidos, Servicio de Medicina Interna, Hospital Universitario de Bellvitge, Universitat de Barcelona, CIBERobn-ISCIII Barcelona, Barcelona, España.
authors.forename: Xavier
authors.initials: X
authors.lastname: Pintó Sala
authors.affiliation: Servicio de Endocrinología, Hospital Clínico Universitario, Universitat de València, Valencia, España.
authors.forename: Juan F
authors.initials: JF
authors.lastname: Ascaso Gimilio
authors.affiliation: Servicio de Medicina Interna, Hospital Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Jesús
authors.initials: J
authors.lastname: Millán Nuñez-Cortés
authors.affiliation: Centro de Salud de Repelega, Osakidetza, Portugalete (Vizcaya), España.
authors.forename: Adalberto
authors.initials: A
authors.lastname: Serrano Cumplido
mesh_terms: D000419:Albuminuria; D002318:Cardiovascular Diseases; D032921:Consensus; D003697:Delphi Technique; D050171:Dyslipidemias / Q000175:diagnosis* / Q000628:therapy*; D005919:Glomerular Filtration Rate; D006801:Humans; D008055:Lipids / Q000097:blood; D051436:Renal Insufficiency, Chronic / Q000150:complications*; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D008055:Lipids
keywords: Cardiovascular risk; Chronic kidney disease; Dislipidemia; Dyslipidaemia; Enfermedad renal crónica; Estatinas; Riesgo cardiovascular; Statins