title: Opportunities for glyconanomaterials in personalized medicine.
abstract: In this feature article we discuss the particular relevance of glycans as components or targets of functionalized nanoparticles (NPs) for potential applications in personalized medicine but we will not enter into descriptions for their preparation. For a more general view covering the preparation and applications of glyconanomaterials the reader is referred to a number of recent reviews. The combination of glyco- and nanotechnology is already providing promising new tools for more personalized solutions to diagnostics and therapy. Current applications relevant to personalized medicine include drug targeting, localized radiation therapy, imaging of glycan expression of cancer cells, point of care diagnostics, cancer vaccines, photodynamic therapy, biosensors, and glycoproteomics.
authors.affiliation: CIC biomaGUNE, Glycotechnology Laboratory, Paseo Miramón 182, 20009 San Sebastian, Spain. nreichardt@cicbiomagune.es and CIBER BBN, Paseo Miramón 182, 20009 San Sebastian, Spain.
authors.forename: Niels-Christian
authors.initials: NC
authors.lastname: Reichardt
authors.affiliation: CIC biomaGUNE, Glycotechnology Laboratory, Paseo Miramón 182, 20009 San Sebastian, Spain. nreichardt@cicbiomagune.es.
authors.forename: Manuel
authors.initials: M
authors.lastname: Martín-Lomas
authors.affiliation: CIC biomaGUNE, Glycotechnology Laboratory, Paseo Miramón 182, 20009 San Sebastian, Spain. nreichardt@cicbiomagune.es.
authors.forename: Soledad
authors.initials: S
authors.lastname: Penadés
mesh_terms: D006801:Humans; D050997:Nanomedicine; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D011134:Polysaccharides / Q000096:biosynthesis / Q000737:chemistry*; D057285:Precision Medicine
chemical_list: D011134:Polysaccharides