title: Body fat and blood rheology: Evaluation of the association between different adiposity indices and blood viscosity.
abstract: BACKGROUND
  In recent years, new measures of body adiposity have been introduced: lipid accumulation product (LAP), body adiposity index (BAI) and body shape index (ABSI). These indices have been demonstrated to better associate with cardiovascular disease than other measures of adiposity.
  
  
  OBJECTIVE
  The aim of the present study was to evaluate if LAP or BAI better associate with blood viscosity than other measures of adiposity (body mass index, BMI; waist circumference, WC; waist-to-hip ratio, W/HR; waist-to-height ratio, W/HtR).
  
  
  METHODS
  344 subjects were recruited for the present investigation. Exclusion criteria were: diabetes, elevated triglycerides, smoking and drug use. Blood lipids and glucose were measured by routine methods. Blood and plasma viscosity were measured by a cone-plate viscometer. Adiposity measures were computed as previously described.
  
  
  RESULTS
  In simple correlation analyses, blood viscosity (BV) correlated with BMI, BAI, and LAP in males and with LAP in females. Correlations between plasma viscosity and adiposity indices were weak and not statistically significant. Other variables significantly related with BV were: gender, HDL- and LDL-Cholesterol, and triglycerides (p < 0.05). In multiple regression analysis only LAP was associated with BV.
  
  
  CONCLUSIONS
  Our data suggest that LAP index is strongly associated to blood viscosity. This result, along with previous evidence, identifies LAP index as a potential cardiovascular risk marker.
authors.forename: Cesare
authors.initials: C
authors.lastname: Tripolino
authors.forename: Concetta
authors.initials: C
authors.lastname: Irace
authors.forename: Claudio
authors.initials: C
authors.lastname: Carallo
authors.forename: Faustina Barbara
authors.initials: FB
authors.lastname: Scavelli
authors.forename: Agostino
authors.initials: A
authors.lastname: Gnasso
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D050154:Adiposity / Q000502:physiology*; D001809:Blood Viscosity / Q000502:physiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D012212:Rheology; D012307:Risk Factors
keywords: Blood rheology; adiposity indices; cardiovascular risk