title: A Highly Efficient Copper-Mediated Radioiodination Approach Using Aryl Boronic Acids.
abstract: A convenient and quantitative radioiodination method by copper-mediated cross-coupling of aryl boronic acids was developed. The mild labeling conditions, ready availability of the boronic acid substrate, simple operation, broad functional group tolerance and excellent radiochemical yield (RCY) make this a practical strategy for radioiodine labeling without further purification.
authors.affiliation: Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, P. R. China.
authors.forename: Pu
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, P. R. China.
authors.forename: Rongqiang
authors.initials: R
authors.lastname: Zhuang
authors.affiliation: Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, P. R. China.
authors.forename: Zhide
authors.initials: Z
authors.lastname: Guo
authors.affiliation: Zhongshan Hospital Affiliated of Xiamen University, Xiamen, 361004, P. R. China.
authors.forename: Xinhui
authors.initials: X
authors.lastname: Su
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (USA), Bethesda, Maryland, 20892, USA.
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
authors.affiliation: Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, P. R. China.
authors.forename: Xianzhong
authors.identifier: http://orcid.org/0000-0001-8591-8301
authors.initials: X
authors.lastname: Zhang
keywords: copper catalysts; molecular imaging; radiochemistry; radioiodination; radiopharmaceuticals