title: I-Cubed (Infection, Immunity, and Inflammation) and the Human Microbiome.
abstract: Medical science is just now realizing the full importance of the microbial world. Thanks to developments such as low-cost high-throughput sequencing of microbial communities comprising the human microbiome, the identity and function of unculturable microbes are being unveiled. Public health officials and neuroepidemiology researchers will be called on to guide the understanding of I-Cubed illnesses and the implications of the human microbiome for communicable and noncommunicable diseases, as the natural history is appreciated and the responsiveness of given medical and neurologic disorders to a variety of medical approaches, including strong antibiotics and immune-modulatory therapy is established.
authors.affiliation: Division of Neuroepidemiology, Department of Neurology, New York University School of Medicine, New York, NY, USA; College of Global Public Health, New York University, New York, NY, USA. Electronic address: youngd01@nyu.edu.
authors.forename: David S
authors.initials: DS
authors.lastname: Younger
mesh_terms: D006801:Humans; D007109:Immunity / Q000276:immunology / Q000502:physiology*; D007239:Infections / Q000453:epidemiology / Q000382:microbiology* / Q000503:physiopathology; D007249:Inflammation / Q000453:epidemiology / Q000382:microbiology* / Q000503:physiopathology; D064307:Microbiota / Q000235:genetics / Q000502:physiology*
keywords: Human microbiome; I-Cubed; Immunity; Infection; Inflammation; Neurology; Public health