title: Carotid Artery Stenting for Acute Ischemic Stroke Patients after Intravenous Recombinant Tissue Plasminogen Activator Treatment.
abstract: We herein report three ischemic stroke patients who underwent emergency carotid artery stenting after receiving intravenous tissue plasminogen activator (t-PA) treatment. All patients received antiplatelet medications immediately before stent placement for loading as well as dual antiplatelet therapy after stenting. Under high-dose and dual antiplatelet therapy, none of the three patients showed symptomatic intracranial hemorrhaging. However, one case showed reocclusion of the placed stent after acute thrombosis. As a result, new treatment strategies for the use of antiplatelet agents during emergency stent placement must be developed, particularly for patients who have received intravenous t-PA therapy.
authors.affiliation: Department of Neurology, Saitama Medical University International Medical Center, Japan.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Deguchi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Neki
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Yamane
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Ishihara
authors.forename: Norio
authors.initials: N
authors.lastname: Tanahashi
authors.forename: Masaki
authors.initials: M
authors.lastname: Takao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002339:Carotid Arteries / Q000601:surgery*; D006801:Humans; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D015607:Stents; D020521:Stroke / Q000188:drug therapy* / Q000601:surgery*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage
chemical_list: D010975:Platelet Aggregation Inhibitors; D010959:Tissue Plasminogen Activator