title: Total Synthesis of Coprinol.
abstract: The first synthesis of coprinol has been achieved from 2-methoxy-3,5-dimethylbenzaldehyde via the intermediacy of an indanone derivative where dialkylation, Friedel-Crafts acylation, demethylation, and regioselective formation of a primary -OH group from a chloroacetyl group are the key steps.
authors.affiliation: Centre for Applied Chemistry, Central University of Jharkhand , Brambe, Ranchi 835205, India.
authors.forename: Muthiah
authors.initials: M
authors.lastname: Suresh
authors.affiliation: Centre for Applied Chemistry, Central University of Jharkhand , Brambe, Ranchi 835205, India.
authors.forename: Navin
authors.initials: N
authors.lastname: Kumar
authors.affiliation: School of Chemistry, University of Hyderabad , Central University P.O., Hyderabad 500046, India.
authors.forename: Gorre
authors.initials: G
authors.lastname: Veeraraghavaiah
authors.affiliation: Centre for Applied Chemistry, Central University of Jharkhand , Brambe, Ranchi 835205, India.
authors.forename: Sunit
authors.initials: S
authors.lastname: Hazra
authors.affiliation: Centre for Applied Chemistry, Central University of Jharkhand , Brambe, Ranchi 835205, India.
authors.forename: Raj Bahadur
authors.initials: RB
authors.lastname: Singh
mesh_terms: D000215:Acylation; D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001547:Benzaldehydes; D012717:Sesquiterpenes; C426845:coprinol