title: Experimental Models of Oral Biofilms Developed on Inert Substrates: A Review of the Literature.
abstract: The oral ecosystem is a very complex environment where more than 700 different bacterial species can be found. Most of them are organized in biofilm on dental and mucosal surfaces. Studying this community is important because a rupture in stability can lead to the preeminence of pathogenic microorganisms, causing dental decay, gingivitis, or periodontitis. The multitude of species complicates biofilm analysis so its reproduction, collection, and counting are very delicate. The development of experimental models of dental biofilms was therefore essential and multiplein vitrodesigns have emerged, each of them especially adapted to observing biofilm formation of specific bacteria within specific environments. The aim of this review is to analyze oral biofilm models.
authors.affiliation: Université de Bordeaux, 16 Cours de la Marne, 33082 Bordeaux, France.
authors.forename: Lopez-Nguyen
authors.initials: LN
authors.lastname: Darrene
authors.affiliation: Université de Bordeaux, 16 Cours de la Marne, 33082 Bordeaux, France; ISVV, EA 4577 Unité de Recherche Oenologie, Institut Polytechnique de Bordeaux, Université de Bordeaux, 33140 Villenave d'Ornon, France.
authors.forename: Badet
authors.identifier: 0000-0003-3518-8608
authors.initials: B
authors.lastname: Cecile
mesh_terms: D001419:Bacteria / Q000254:growth & development*; D001422:Bacterial Adhesion / Q000502:physiology; D061249:Batch Cell Culture Techniques / Q000379:methods; D018441:Biofilms / Q000254:growth & development*; D040761:Biomimetic Materials / Q000737:chemistry*; D018929:Cell Culture Techniques / Q000379:methods*; D009055:Mouth / Q000382:microbiology*; D012463:Saliva / Q000382:microbiology*