title: Pd-Catalyzed C(sp3)-C(sp2) cross-coupling of Y(CH2SiMe3)3(THF)2with vinyl bromides and triflates.
abstract: Pd-Catalyzed C(sp3)-C(sp2) cross-coupling of Y(CH2SiMe3)3(THF)2with vinyl bromides and triflates has been developed for efficient synthesis of various allyltrimethylsilanes. The cross-coupling reaction was conducted at room temperature with low catalyst loading of either Pd(PPh3)4or Pd(PPh3)2Cl2, and exhibited high efficiency and a broad substrate scope. In combination with the cross-coupling by the Lewis-acid catalyzed Hosomi-Sakurai reaction, a novel three-component one-pot cascade reaction was then accomplished to deliver homoallylic alcohols and ethers with high regioselectivity and diastereoselectivity. The three-component reaction defined the yttrium complex as a novel one-carbon synthon, which could either trigger bifunctionalization of alkenes or link two electrophiles and would find applications in organic synthesis.
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. yaobo@bit.edu.cn xfli@bit.edu.cn.
authors.forename: Guilong
authors.initials: G
authors.lastname: Cai
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. yaobo@bit.edu.cn xfli@bit.edu.cn.
authors.forename: Zhibing
authors.initials: Z
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. yaobo@bit.edu.cn xfli@bit.edu.cn.
authors.forename: Wenchao
authors.initials: W
authors.lastname: Wu
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. yaobo@bit.edu.cn xfli@bit.edu.cn.
authors.forename: Bo
authors.initials: B
authors.lastname: Yao
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. yaobo@bit.edu.cn xfli@bit.edu.cn.
authors.forename: Shaowen
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. yaobo@bit.edu.cn xfli@bit.edu.cn.
authors.forename: Xiaofang
authors.identifier: http://orcid.org/0000-0003-0677-6689
authors.initials: X
authors.lastname: Li