title: Length and sequence effect on the B-Z transition of [d(A-T)n]2oligonucleotide induced by a cationic porphyrin.
abstract: trans-BMPyP induced the B-Z transition for alternated AT oligonucleotides as it was evident by inversed CD spectrum. The transition occurred simultaneously with appearance of the extensive stacking of porphyrin. Complete B-Z transition required at least 14 base-pairs long. Insertion of one or two GC base pairs prevented the B-Z transition.
authors.affiliation: Department of Chemistry, Yeungnam University, 212 Dae-dong, Gyeongsan City, Gyeong-buk 712-749, Republic of Korea.
authors.forename: Jong Heon
authors.initials: JH
authors.lastname: Shin
authors.affiliation: Department of Chemistry, Yeungnam University, 212 Dae-dong, Gyeongsan City, Gyeong-buk 712-749, Republic of Korea.
authors.forename: Yoon Mo
authors.initials: YM
authors.lastname: Hwang
authors.affiliation: Department of Chemistry, Yeungnam University, 212 Dae-dong, Gyeongsan City, Gyeong-buk 712-749, Republic of Korea.
authors.forename: Yoon Jung
authors.initials: YJ
authors.lastname: Jang
authors.affiliation: Department of Chemistry, Yeungnam University, 212 Dae-dong, Gyeongsan City, Gyeong-buk 712-749, Republic of Korea. Electronic address: seogkim@yu.ac.kr.
authors.forename: Seog K
authors.initials: SK
authors.lastname: Kim
mesh_terms: D001483:Base Sequence; D002412:Cations; D002942:Circular Dichroism; D059371:DNA, B-Form; D043542:DNA, Z-Form; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D009841:Oligonucleotides / Q000737:chemistry*; D011061:Poly A / Q000737:chemistry; D011071:Poly T / Q000737:chemistry; D011166:Porphyrins / Q000494:pharmacology*
chemical_list: D002412:Cations; D059371:DNA, B-Form; D043542:DNA, Z-Form; D009841:Oligonucleotides; D011166:Porphyrins; D011061:Poly A; D011071:Poly T; C008950:poly A-T
keywords: B-Z transition; Circular dichroism; Oligonucleotide; Porphyrin; Z-DNA