title: Portrait of Candida Species Biofilm Regulatory Network Genes.
abstract: Most cases of candidiasis have been attributed to Candida albicans, but Candida glabrata, Candida parapsilosis and Candida tropicalis, designated as non-C. albicans Candida (NCAC), have been identified as frequent human pathogens. Moreover, Candida biofilms are an escalating clinical problem associated with significant rates of mortality. Biofilms have distinct developmental phases, including adhesion/colonisation, maturation and dispersal, controlled by complex regulatory networks. This review discusses recent advances regarding Candida species biofilm regulatory network genes, which are key components for candidiasis.
authors.affiliation: Centre of Biological Engineering (CEB), University of Minho, Braga, Portugal.
authors.forename: Daniela
authors.initials: D
authors.lastname: Araújo
authors.affiliation: Centre of Biological Engineering (CEB), University of Minho, Braga, Portugal.
authors.forename: Mariana
authors.initials: M
authors.lastname: Henriques
authors.affiliation: Centre of Biological Engineering (CEB), University of Minho, Braga, Portugal. Electronic address: soniasilva@deb.uminho.pt.
authors.forename: Sónia
authors.initials: S
authors.lastname: Silva
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D002175:Candida / Q000254:growth & development / Q000472:pathogenicity*; D002177:Candidiasis / Q000382:microbiology / Q000473:pathology*; D002448:Cell Adhesion / Q000502:physiology*; D006801:Humans; D025301:Hyphae / Q000235:genetics / Q000254:growth & development*
keywords: Candida species; biofilm; regulatory genes