title: Screening of Oral Potentially Malignant Disorders Using Exfoliative Cytology: A Diagnostic Modality.
abstract: Objective. Oral exfoliative cytology (OEC) has been implemented in the diagnosis of pathologic lesions for ages. The present study was undertaken to evaluate the cytomorphological features of some of the commonest potentially malignant disorders (leukoplakia, lichen planus, and oral submucous fibrosis) through a simple procedure and illustrate its importance in mass screening.Materials and Method. A total of 160 subjects with 25-50 years of age were included in the study. Among them, 40 were clinically diagnosed with oral leukoplakia, 40 were diagnosed with oral lichen planus, 40 were diagnosed with oral submucous fibrosis, and 40 were in the control group. The prepared smears were subjected to Papanicolaou stain and analyzed microscopically for the evaluation of the cytomorphological features.Results and Discussion. When analyzed microscopically, 36 (90%) out of the 40 oral leukoplakic lesions showed Class II cytological features whereas 4 (10%) revealed Class I features. Among 40 patients with oral lichen planus, 26 (65%) showed Class II features while the remaining 14 (35%) revealed Class I features. In 40 subjects with oral submucous fibrosis, 32 (80%) showed Class II features while the other 8 (20%) showed Class I features. All the 40 control subjects showed Class I features. Thus, OEC can be widely advocated as an addition to clinical conclusion and an adjunct to biopsy.
authors.affiliation: Department of Oral Pathology & Microbiology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal 721645, India.
authors.forename: Arpita
authors.identifier: 0000-0003-4382-0351
authors.initials: A
authors.lastname: Kabiraj
authors.affiliation: Department of Oral Medicine & Radiology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal 721645, India.
authors.forename: Tanya
authors.identifier: 0000-0002-9664-4999
authors.initials: T
authors.lastname: Khaitan
authors.affiliation: Department of Periodontics, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal 721645, India.
authors.forename: Debarati
authors.initials: D
authors.lastname: Bhowmick
authors.affiliation: Department of Oral Medicine & Radiology, Kamineni Institute of Dental Sciences, Narketpally, Andhra Pradesh 508254, India.
authors.forename: Uday
authors.initials: U
authors.lastname: Ginjupally
authors.affiliation: Department of Biochemistry, IQ City Medical College, Durgapur, West Bengal 713206, India.
authors.forename: Aritri
authors.initials: A
authors.lastname: Bir
authors.affiliation: Department of Dentistry, Jawaharlal Nehru Medical College & Hospital, Kalyani, West Bengal 74123, India.
authors.forename: Kushal
authors.initials: K
authors.lastname: Chatterjee