title: High incidence of activating STAT5B mutations in CD4-positive T-cell large granular lymphocyte leukemia.
authors.affiliation: Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
authors.forename: Emma I
authors.initials: EI
authors.lastname: Andersson
authors.affiliation: Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tanahashi
authors.affiliation: Division of Hematology, Department of Internal Medicine, and.|Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Nodoka
authors.initials: N
authors.lastname: Sekiguchi
authors.affiliation: Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
authors.forename: Vanessa Rebecca
authors.initials: VR
authors.lastname: Gasparini
authors.affiliation: Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Bortoluzzi
authors.affiliation: Division of Hematology, Department of Internal Medicine, and.
authors.forename: Toru
authors.initials: T
authors.lastname: Kawakami
authors.affiliation: Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Matsuda
authors.affiliation: Department of Medicine and Clinical Sciences, Gunma University School of Medicine, Maebashi, Japan.
authors.forename: Takeki
authors.initials: T
authors.lastname: Mitsui
authors.affiliation: Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
authors.forename: Samuli
authors.initials: S
authors.lastname: Eldfors
authors.affiliation: Computational Genomics Laboratory, Department of Molecular Medicine, University of Padova, Padova, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Bortoluzzi
authors.affiliation: Computational Genomics Laboratory, Department of Molecular Medicine, University of Padova, Padova, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Coppe
authors.affiliation: Computational Genomics Laboratory, Department of Molecular Medicine, University of Padova, Padova, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Binatti
authors.affiliation: Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
authors.forename: Sonja
authors.initials: S
authors.lastname: Lagström
authors.affiliation: Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
authors.forename: Pekka
authors.initials: P
authors.lastname: Ellonen
authors.affiliation: Department of Medical Science Technology, School of Health Sciences at Fukuoka, International University of Health and Welfare, Fukuoka, Japan.
authors.forename: Noriyasu
authors.initials: N
authors.lastname: Fukushima
authors.affiliation: Division of Hematology, Department of Internal Medicine, and.
authors.forename: Sayaka
authors.initials: S
authors.lastname: Nishina
authors.affiliation: Division of Hematology, Department of Internal Medicine, and.
authors.forename: Noriko
authors.initials: N
authors.lastname: Senoo
authors.affiliation: Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Sakai
authors.affiliation: Division of Hematology, Department of Internal Medicine, and.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Nakazawa
authors.affiliation: Department of Medicine, Queen Mary Hospital, Hong Kong, China.
authors.forename: Yok-Lam
authors.initials: YL
authors.lastname: Kwong
authors.affiliation: University of Virginia Cancer Center, University of Virginia, Charlottesville, VA.
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Loughran
authors.affiliation: Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.
authors.forename: Jaroslaw P
authors.initials: JP
authors.lastname: Maciejewski
authors.affiliation: Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.|Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland; and.
authors.forename: Satu
authors.identifier: 0000-0002-0816-8241
authors.initials: S
authors.lastname: Mustjoki
authors.affiliation: Department of Clinical Laboratory Investigation, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.|Division of Hematology, Department of Internal Medicine, and.|Department of Biomedical Laboratory Sciences, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Ishida
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015496:CD4-Positive T-Lymphocytes; D005260:Female; D006801:Humans; D015994:Incidence; D054066:Leukemia, Large Granular Lymphocytic / Q000453:epidemiology / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009154:Mutation; D009363:Neoplasm Proteins / Q000235:genetics* / Q000378:metabolism; D050799:STAT5 Transcription Factor / Q000235:genetics* / Q000378:metabolism
chemical_list: D009363:Neoplasm Proteins; D050799:STAT5 Transcription Factor; C494095:STAT5B protein, human