title: Effect of ROS Inhalation on Systemic and Local Hemodynamics in Rats.
abstract: The effects of inhalation of singlet oxygen mixture, dry and humidified ozone-oxygen mixture, and ozonated oils on heart rate variability as well as on the rate and control mechanisms of microcirculation were examined in rats. The most optimal were the responses of systemic and regional hemodynamics to inhalation of the gas produced by a generator of singlet oxygen and humidified ozone-oxygen mixtures. Singlet oxygen stabilized the cardiac rhythm and augmented microcirculation via activation of "internal" (endothelial and neurogenic) regulatory mechanisms.
authors.affiliation: Privolzhsky (Volga Region) Federal Medical Research Center, Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia. cryst-mart@yandex.ru.
authors.forename: A K
authors.initials: AK
authors.lastname: Martusevich
authors.affiliation: Privolzhsky (Volga Region) Federal Medical Research Center, Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia.
authors.forename: S P
authors.initials: SP
authors.lastname: Peretyagin
authors.affiliation: Privolzhsky (Volga Region) Federal Medical Research Center, Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Martusevich
authors.affiliation: Privolzhsky (Volga Region) Federal Medical Research Center, Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia.
authors.forename: P V
authors.initials: PV
authors.lastname: Peretyagin
mesh_terms: D000280:Administration, Inhalation; D000818:Animals; D004353:Drug Evaluation, Preclinical; D006339:Heart Rate / Q000187:drug effects; D008833:Microcirculation / Q000187:drug effects*; D010126:Ozone / Q000008:administration & dosage*; D051381:Rats; D026082:Singlet Oxygen / Q000008:administration & dosage*
chemical_list: D026082:Singlet Oxygen; D010126:Ozone
keywords: heart rate variability; microcirculation; ozone; reactive oxygen species; singlet oxygen