title: Regression of vascular calcification in a parathyroidectomized patient on dialysis with untreated hypocalcemia over 12-year follow-up .
abstract: Although some experimental targets involved in calcium deposition are emerging, no intervention has been described to reliably reverse vascular calcification (VC). We report a case of severe VC regression in a parathyroidectomized patient on hemodialysis over 12-year follow-up, highlighting the use of calcium-free phosphate binders and a 2.5 mEq/L calcium dialysate for reducing calcium loading, despite persistent asymptomatic hypocalcemia occurrences. This case suggests that phosphate-binder choice and calcium dialysate concentration could be influenced by other components of CKD-MBD besides biochemical parameters, such as the presence of VC, so concluding that asymptomatic hypocalcemia may not be as harmful as once supposed, and conferring greater prognostic weight to the presence of VC than to calcium levels. .
authors.forename: Pablo
authors.initials: P
authors.lastname: Molina
authors.forename: José L
authors.initials: JL
authors.lastname: Górriz
authors.forename: Sandra
authors.initials: S
authors.lastname: Beltrán
authors.forename: Belén
authors.initials: B
authors.lastname: Vizcaino
authors.forename: Luis M
authors.initials: LM
authors.lastname: Pallardo
mesh_terms: D002118:Calcium / Q000008:administration & dosage*; D002614:Chelating Agents / Q000627:therapeutic use*; D015314:Dialysis Solutions / Q000737:chemistry; D005500:Follow-Up Studies; D006801:Humans; D006996:Hypocalcemia / Q000628:therapy; D008297:Male; D008875:Middle Aged; D016105:Parathyroidectomy; D010710:Phosphates; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000628:therapy; D013997:Time Factors; D061205:Vascular Calcification / Q000209:etiology / Q000628:therapy*
chemical_list: D002614:Chelating Agents; D015314:Dialysis Solutions; D010710:Phosphates; D002118:Calcium