title: Dataset of mRNA levels for dopaminergic receptors, adrenoceptors and tyrosine hydroxylase in lymphocytes from subjects with clinically isolated syndromes.
abstract: This data article presents a dataset of mRNA levels for dopaminergic receptors, adrenoceptors and for tyrosine hydoxylase, the rate-limiting enzyme in the synthesis of catecholamines, in peripheral blood mononuclear cells as well as in CD4+ T effector and regulatory cells from subjects with clinically isolated syndromes (CIS), which is a first episode of neurological disturbance(s) suggestive of multiple sclerosis. CIS subjects are divided into two groups according to their eventual progression, after 12 months from CIS, to clinically established multiple sclerosis. The data reported are related to the article entitled "Dopaminergic receptors and adrenoceptors in circulating lymphocytes as putative biomarkers for the early onset and progression of multiple sclerosis" (M. Cosentino, M. Zaffaroni, M. Legnaro, R. Bombelli, L. Schembri, D. Baroncini, A. Bianchi, R. Clerici, M. Guidotti, P. Banfi, G. Bono, F. Marino, 2016) [1].
authors.affiliation: Center of Research in Medical Pharmacology, University of Insubria, Varese, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Cosentino
authors.affiliation: Multiple Sclerosis Center, Hospital ׳S. Antonio Abate׳, Gallarate, VA, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Zaffaroni
authors.affiliation: Center of Research in Medical Pharmacology, University of Insubria, Varese, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Legnaro
authors.affiliation: Center of Research in Medical Pharmacology, University of Insubria, Varese, Italy.
authors.forename: Raffaella
authors.initials: R
authors.lastname: Bombelli
authors.affiliation: Center of Research in Medical Pharmacology, University of Insubria, Varese, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Schembri
authors.affiliation: Multiple Sclerosis Center, Hospital ׳S. Antonio Abate׳, Gallarate, VA, Italy.
authors.forename: Damiano
authors.initials: D
authors.lastname: Baroncini
authors.affiliation: Multiple Sclerosis Center, Hospital ׳S. Antonio Abate׳, Gallarate, VA, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Bianchi
authors.affiliation: Neurological Department, Valduce Hospital, Como, Italy.
authors.forename: Raffaella
authors.initials: R
authors.lastname: Clerici
authors.affiliation: Neurological Department, Valduce Hospital, Como, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Guidotti
authors.affiliation: Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Banfi
authors.affiliation: Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Bono
authors.affiliation: Center of Research in Medical Pharmacology, University of Insubria, Varese, Italy.
authors.forename: Franca
authors.initials: F
authors.lastname: Marino
keywords: Adrenoceptors; CD4+ T effector lymphocytes; CD4+ T regulatory lymphocytes; Clinically isolated syndrome; Dopaminergic receptors; Multiple sclerosis; Peripheral blood mononuclear cells; mRNA levels