title: Fractionation, preliminary structural characterization and bioactivities of polysaccharides from Sargassum pallidum.
abstract: Sargassum pallidum polysaccharides were fractioned using a DEAE-Sepharose fast-flow column and four polysaccharide fractions (SP-P1, SP-P2, PV-P3 and SP-P4) were obtained. Structural analyses indicated that SP-P2 and SP-P4 had higher molecular weights than SP-P1 and SP-P3. SP-P2, SP-P3 and SP-P4 comprised of fucose, rhamnose, arabinose, galactose, glucose, xylose, and mannose in a similar molar ratio, while SP-P1 did not contain arabinose. SP-P2 and SP-P4 had a similar number of (1→6) or (1→) glycosidic linkages (1→2) or (1→4) glycosidic linkages and (1→3) glycosidic linkages, while SP-P1 and SP-P3 contained a small number of (1→3) glycosidic linkages. SP-P2 exhibited better bioactivities than SP-P1, SP-P3 and SP-P4, including antioxidant, anti-hemolysis inhibitory, α-amylase and α-glucosidase inhibitory and antiproliferative activities. These data suggest that S. pallidum has four polysaccharide fractions with different structural features and bioactivities and SP-P2 has potential to be explored as a functional food or complementary medicine.
authors.affiliation: School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Li
authors.affiliation: School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China.
authors.forename: Xiangshi
authors.initials: X
authors.lastname: Li
authors.affiliation: School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China; Department of Food Science, Stocking Hall, Cornell University, Ithaca, NY 14853, USA. Electronic address: feyoulijun@scut.edu.cn.
authors.forename: Lijun
authors.initials: L
authors.lastname: You
authors.affiliation: School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China. Electronic address: lfxfu@scut.edu.cn.
authors.forename: Xiong
authors.initials: X
authors.lastname: Fu
authors.affiliation: School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China; Department of Food Science, Stocking Hall, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Rui Hai
authors.initials: RH
authors.lastname: Liu
mesh_terms: D002236:Carbohydrate Conformation; D005591:Chemical Fractionation; D011134:Polysaccharides / Q000737:chemistry*; D044647:Sargassum / Q000737:chemistry*
chemical_list: D011134:Polysaccharides
keywords: Bioactivities; Polysaccharides; Sargassum pallidum; Structural characteristics