title: Contemporary Role of Radiotherapy in the Management of Primary Penile Tumors and Metastatic Disease.
abstract: Squamous cell cancer of the penis is a radiocurable malignancy all too often managed solely by partial or total penectomy. Effective management of the primary tumor while preserving penile morphology and function is a priority. External radiotherapy and brachytherapy have a role to play in the definitive management of the primary tumor. Surgical nodal staging remains a cornerstone of management because it is the strongest predictor of survival, and inguinal status determines pelvic management. Postoperative radiotherapy of the regional nodes for high-risk pathology is indicated. Chemoradiotherapy should be considered as neoadjuvant treatment for unresectable nodes or as definitive management.
authors.affiliation: Department of Surgery, Center for the Southern Interior, British Columbia Cancer Agency, 399 Royal Avenue, Kelowna V1Y5L3, British Columbia, Canada. Electronic address: jcrook@bccancer.bc.ca.
authors.forename: Juanita
authors.initials: J
authors.lastname: Crook
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000556:secondary / Q000601:surgery*; D003131:Combined Modality Therapy; D019468:Disease Management; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D010412:Penile Neoplasms / Q000473:pathology / Q000532:radiotherapy*
keywords: Brachytherapy; Combined chemoradiotherapy; Penile cancer; Penile cancer clinical trials; Postoperative radiotherapy; Radiotherapy; Radiotherapy management of regional lymph nodes; Surface mold radiotherapy