title: 18F-FDG-PET Correlates of Impulse Control Disorder in a Diabetic Patient.
abstract: BACKGROUND
  Studies have already shown that hyperglycemia and insulin resistance are significantly associated with the impairment of cerebral glucose metabolism that may secondary lead to cognitive disturbances. In this study, we aimed to evaluate the neurometabolic correlates of diabetes in a patient with Intermittent explosive disorder (IED).
  
  
  METHODS
  We have investigated the cerebral glucose metabolism via 2-[18F]-fluoro-2- deoxy-D-glucose positron emission tomography (FDG-PET) in a diabetic patient with aggressive outbursts.
  
  
  RESULTS
  We have found significantly reduced glucose uptake in left temporoparietal region, pontin area, and left nucleus lentiformis.
  
  
  CONCLUSIONS
  Our present results indicate decreased cerebral glucose metabolism in specific cerebral cortical and subcortical areas. The main limitation of this report is that, this is a single case study and that these findings need to be replicated in well- conducted randomized controlled studies by using additional neuroquantitative methods.
authors.affiliation: Istanbul-Medipol University, Department of Neurology, Istanbul,. Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Yulug
authors.forename: Lütfü
authors.initials: L
authors.lastname: Hanoglu
authors.forename: Ahmet Mithat
authors.initials: AM
authors.lastname: Tavlı
authors.forename: Tansel
authors.initials: T
authors.lastname: Cakir
authors.forename: Elmir
authors.initials: E
authors.lastname: Khanmammadov
authors.forename: Oktay
authors.initials: O
authors.lastname: Olmuscelik
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D019788:Fluorodeoxyglucose F18; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods*
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: Diabetes mellitus; FDG-PET; impulse control disorder.