title: PIFA-mediated ethoxyiodination of enamides with potassium iodide.
abstract: The regioselective ethoxyiodination of enamides was developed using PIFA in combination with potassium iodide in ethanol. The reaction proceeds regioselectively with excellent yields and diastereoselectivities, providing valuable synthons for further functionalisations. Control experiments were conducted, indicating that the transformation occurs through an ionic manifold involving an in situ generated hypoiodite species.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Univ. P.-Sud, Univ. Paris-Saclay, 1, av. de la Terrasse, 91198 Gif-sur-Yvette, France. robert.dodd@cnrs.fr kevin.cariou@cnrs.fr.
authors.forename: R
authors.initials: R
authors.lastname: Beltran
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Univ. P.-Sud, Univ. Paris-Saclay, 1, av. de la Terrasse, 91198 Gif-sur-Yvette, France. robert.dodd@cnrs.fr kevin.cariou@cnrs.fr.
authors.forename: S
authors.initials: S
authors.lastname: Nocquet-Thibault
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Univ. P.-Sud, Univ. Paris-Saclay, 1, av. de la Terrasse, 91198 Gif-sur-Yvette, France. robert.dodd@cnrs.fr kevin.cariou@cnrs.fr.
authors.forename: F
authors.initials: F
authors.lastname: Blanchard
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Univ. P.-Sud, Univ. Paris-Saclay, 1, av. de la Terrasse, 91198 Gif-sur-Yvette, France. robert.dodd@cnrs.fr kevin.cariou@cnrs.fr.
authors.forename: R H
authors.initials: RH
authors.lastname: Dodd
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Univ. P.-Sud, Univ. Paris-Saclay, 1, av. de la Terrasse, 91198 Gif-sur-Yvette, France. robert.dodd@cnrs.fr kevin.cariou@cnrs.fr.
authors.forename: K
authors.identifier: http://orcid.org/0000-0002-5854-9632
authors.initials: K
authors.lastname: Cariou