title: Palladium-catalyzed Mizoroki-Heck-type reactions of [Ph2SRfn][OTf] with alkenes at room temperature.
abstract: The first Pd-catalyzed Mizoroki-Heck-type reaction of [Ph2SRfn][OTf] with alkenes is described. The reaction of [Ph2SRfn][OTf] (Rfn= CF3, CH2CF3) with alkenes in the presence of 10 mol% Pd[P(t-Bu)3]2and TsOH at room temperature provided the corresponding phenylation products in good to high yields. The bases that benefit the traditional Mizoroki-Heck reactions severely inhibited the transformation with [Ph2SRfn][OTf], whereas acids significantly improved the reaction. This protocol supplies a new class of cross-coupling partners for Mizoroki-Heck-type reactions and gains important insights into the reactivity of phenylsulfonium salts either with or without fluorine-containing alkyl groups as the promising phenylation reagents in organic synthesis.
authors.affiliation: School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China. cpzhang@whut.edu.cn.
authors.forename: Shi-Meng
authors.initials: SM
authors.lastname: Wang
authors.affiliation: School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China. cpzhang@whut.edu.cn.
authors.forename: Hai-Xia
authors.initials: HX
authors.lastname: Song
authors.affiliation: School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China. cpzhang@whut.edu.cn.
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Wang
authors.affiliation: School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China. cpzhang@whut.edu.cn.
authors.forename: Nan
authors.initials: N
authors.lastname: Liu
authors.affiliation: School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China. cpzhang@whut.edu.cn.
authors.forename: Hua-Li
authors.initials: HL
authors.lastname: Qin
authors.affiliation: School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China. cpzhang@whut.edu.cn.
authors.forename: Cheng-Pan
authors.initials: CP
authors.lastname: Zhang