title: Coronary artery calcification in Korean patients with incident dialysis.
abstract: Patients with chronic kidney disease have an extremely high risk of developing cardiovascular disease (CVD). In patients with end-stage renal disease (ESRD), coronary artery calcification (CAC) is associated with increased mortality from CVD.
  
  
  
  The present study aimed to investigate the risk factors for CAC in Korean patients with incident dialysis. Data on 423 patients with ESRD who started dialysis therapy between December 2012 and March 2014 were obtained from 10 university-affiliated hospitals. CAC was identified by using noncontrast-enhanced cardiac multidetector computed tomography. The CAC score was calculated according to the Agatston score, with CAC-positive subjects defined by an Agatston score >0.
  
  
  
  Patients' mean age was 55.6 ± 14.6 years, and 64.1% were men. The CAC-positive rate was 63.8% (270 of 423). Results of univariate analyses showed significant differences in age, sex, etiology of ESRD and comorbid conditions according to the CAC score. However, results of multiple regression analysis showed that only a higher age was significantly associated with the CAC score. Receiver operating characteristic curves showed that the sensitivity and specificity of L-spine radiography for diagnosing CAC were 56% and 91%, respectively, for diagnosing CAC (area under the curve, 0.735).
  
  
  
  CAC was frequent in patients with incident dialysis, and multiple regression analysis showed that only age was significantly associated with the CAC score. In addition, L-spine radiography could be a helpful modality for diagnosing CAC in patients with incident dialysis.
authors.affiliation: Department of Internal Medicine, Gyeongsang National University College of Medicine, Changwon, Korea.
authors.forename: Eunjin
authors.initials: E
authors.lastname: Bae
authors.affiliation: Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.
authors.forename: Eun Yong
authors.initials: EY
authors.lastname: Seong
authors.affiliation: Department of Internal Medicine, Yonsei University Wonju College of Medicine, Kangwon, Korea.
authors.forename: Byoung-Geun
authors.initials: BG
authors.lastname: Han
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Dong Ki
authors.initials: DK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
authors.forename: Chun Soo
authors.initials: CS
authors.lastname: Lim
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Shin-Wook
authors.initials: SW
authors.lastname: Kang
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Cheol Whee
authors.initials: CW
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Chan-Duck
authors.initials: CD
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Chosun University Hospital, Gwangju, Korea.
authors.forename: Byung Chul
authors.initials: BC
authors.lastname: Shin
authors.affiliation: Department of Internal Medicine, Hallym University Sacred Heart Hospital, Pyeongchon, Korea.
authors.forename: Sung Gyun
authors.initials: SG
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Gachon University, Gil Hospital, Incheon, Korea.
authors.forename: Wookyung
authors.initials: W
authors.lastname: Chung
authors.affiliation: Department of Internal Medicine, Dongguk University Medical Center, Goyang, Korea.
authors.forename: Jae Yoon
authors.initials: JY
authors.lastname: Park
authors.affiliation: Medical Department, Sanofi-Aventis Korea, Seoul, Korea.
authors.forename: Joo Yeon
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Yon Su
authors.initials: YS
authors.lastname: Kim
mesh_terms: D002114:Calcinosis / Q000175:diagnosis*; D003324:Coronary Artery Disease / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D007723:Korea; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects* / Q000379:methods; D012307:Risk Factors
keywords: Cardiovascular disease; L-spine radiography; coronary artery calcification; end-stage renal disease