title: Pseudomelanosis duodeni: is there a common denominator?
abstract: A 76-year-old female patient with a past medical history of diabetes mellitus, stage 3 chronic renal failure and iron deficiency anemia was referred for esophagogastroduodenoscopy (EGD) for evaluation of solid food dysphagia. She had been on oral therapy with ferrous sulfate for several years. Besides a Schatzki's ring the EGD revealed a duodenal mucosa with black-speckled pigmentation. Biopsies were performed and disclosed the deposition of brown (hemosiderin) pigment within macrophages in the lamina propria of normal villi. This endoscopic appearance is called pseudomelanosis duodeni (PD).
authors.affiliation: Gastrenterology, Centro Hospitalar São João, Portugal.
authors.forename: Rosa
authors.initials: R
authors.lastname: Coelho
authors.affiliation: Gastroenterology, Centro Hospitalar São João, Portugal.
authors.forename: Armando
authors.initials: A
authors.lastname: Ribeiro
authors.affiliation: Pathology, Centro Hospitalar São João, Portugal.
authors.forename: Roberto
authors.initials: R
authors.lastname: Silva
authors.affiliation: Pathology, Centro Hospitalar São João, Portugal.
authors.forename: Elisabete
authors.initials: E
authors.lastname: Rios
authors.affiliation: Gastroenterology, Centro Hospitalar São João, Portugal.
authors.forename: Marco
authors.initials: M
authors.lastname: Silva
authors.affiliation: Gastroenterology, Centro Hospitalar S. João, Portugal.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Macedo
mesh_terms: D000368:Aged; D001706:Biopsy; D004378:Duodenal Diseases / Q000175:diagnosis / Q000473:pathology*; D004386:Duodenum / Q000473:pathology; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D008548:Melanosis / Q000175:diagnosis / Q000473:pathology*