title: Palliative and End-of-Life Care in Myelodysplastic Syndromes.
abstract: A growing literature demonstrates that MDS is associated with significant impairments in overall quality of life. Given the poor prognosis for many patients with MDS, and the considerable morbidities associated with this disease, there is a critical need to address palliative and end-of-life care needs in this population. However, palliative and end-of-life care issues are under-represented in the MDS literature. In this article, we highlight a growing body of literature that demonstrates unmet palliative and end-of-life care needs in hematologic malignancies, including MDS, and highlight opportunities for further research and quality improvement initiatives to address unmet needs in MDS care.
authors.affiliation: Divisions of Hematology, Medical Oncology, and Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
authors.forename: Myles
authors.initials: M
authors.lastname: Nickolich
authors.affiliation: Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Areej
authors.initials: A
authors.lastname: El-Jawahri
authors.affiliation: Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA. thomas.leblanc@duke.edu.|DUMC, Box 2715, Durham, NC, 27710, USA. thomas.leblanc@duke.edu.
authors.forename: Thomas W
authors.initials: TW
authors.lastname: LeBlanc
mesh_terms: D016208:Databases, Factual; D019337:Hematologic Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D006801:Humans; D009190:Myelodysplastic Syndromes / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D010166:Palliative Care; D011788:Quality of Life
keywords: End-of-life care; Myelodysplastic syndromes; Palliative care; Quality of life