title: Case of Six-Year Disease-Free Survival with Undifferentiated Carcinoma of the Pancreas.
abstract: Undifferentiated carcinoma of the pancreas (UDC) is rare and has a dismal prognosis. Here, we report a case of 6-year disease-free survival with a mixed type of UDC and UDC with osteoclast-like giant cells, with a high mitotic index as well as perineural, lymphatic, vessel, and diaphragmatic invasion. The patient underwent radical distal pancreatectomy and was subsequently treated with adjuvant chemotherapy using gemcitabine plus S-1 followed by maintenance chemotherapy with oral tegafur-uracil. The patient has been doing well with no evidence of recurrence for more than 6 years after surgery.
authors.affiliation: Department of Surgery, IMS Ota Central General Hospital, Ota, Japan; Department of Surgery, Konosu Kyosei Hospital, Konosu, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Saito
authors.affiliation: Department of Surgery, Konosu Kyosei Hospital, Konosu, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kashiyama
authors.affiliation: Department of Surgery, Konosu Kyosei Hospital, Konosu, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Murohashi
authors.affiliation: Department of Surgery, IMS Ota Central General Hospital, Ota, Japan.
authors.forename: Kazunari
authors.initials: K
authors.lastname: Sasaki
authors.affiliation: Department of Surgery, IMS Ota Central General Hospital, Ota, Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Misawa
authors.affiliation: Department of Surgery, IMS Ota Central General Hospital, Ota, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Ohwada
keywords: Drug therapy; Pancreatic carcinoma; Undifferentiated carcinoma