title: Inquilinus limosus in pulmonary disease: case report and review of the literature.
abstract: Inquilinus limosus is a slow growing, gram-negative, oxidase-positive, non-fermentative bacillus that is rarely isolated from clinical samples. When clinically identified, I. limosus is almost exclusively isolated from the respiratory tracts of patients with cystic fibrosis (CF). We report the first case of I. limosus isolation from a pulmonary specimen in an individual without a diagnosis of CF. A review of the English-language literature has been made and shows 33 cases (excluding the present report) in which I. limosus was isolated from the respiratory tracts of patients. Our patient, at 60years of age, is more than two decades older than the any previously reported patient. Similar to previous reports, the I. limosus isolated from her lungs demonstrated intrinsic multidrug resistance. The pathogenicity, clinical relevance, and optimal therapeutic management of I. limosus remains largely unknown due to its infrequent recovery from clinical samples.
authors.affiliation: Department of Laboratory Medicine, Cleveland Clinic, 9500 Euclid Ave, L25, Cleveland, OH 44195, USA. Electronic address: mchughk3@ccf.org.
authors.forename: Kelsey E
authors.initials: KE
authors.lastname: McHugh
authors.affiliation: Department of Laboratory Medicine, Cleveland Clinic, 9500 Euclid Ave, L25, Cleveland, OH 44195, USA.
authors.forename: Daniel D
authors.initials: DD
authors.lastname: Rhoads
authors.affiliation: Department of Laboratory Medicine, Cleveland Clinic, 9500 Euclid Ave, L25, Cleveland, OH 44195, USA.
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Wilson
authors.affiliation: Department of Pulmonary Medicine, Cleveland Clinic, 9500 Euclid Ave, L25, Cleveland, OH 44195, USA.
authors.forename: Kristin B
authors.initials: KB
authors.lastname: Highland
authors.affiliation: Department of Laboratory Medicine, Cleveland Clinic, 9500 Euclid Ave, L25, Cleveland, OH 44195, USA.
authors.forename: Sandra S
authors.initials: SS
authors.lastname: Richter
authors.affiliation: Department of Laboratory Medicine, Cleveland Clinic, 9500 Euclid Ave, L25, Cleveland, OH 44195, USA.
authors.forename: Gary W
authors.initials: GW
authors.lastname: Procop
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001431:Bacteriological Techniques; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D008969:Molecular Sequence Data; D010802:Phylogeny; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012244:Rhodospirillaceae / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S
keywords: Bronchoalveolar lavage; Cystic fibrosis; Gram negative; Inquilinus limosus; Inquilinus spp.; Nonfermenter