title: Functional role of apoptosis in oral diseases: An update.
abstract: Cell death appears to be a basic biological phenomenon which is maintained by the human body. The term apoptosis, also known as programmed cell death, is characterized by several unique morphological and biochemical features. Apoptosis and its different forms are essential for tissue homeostasis. Alteration in molecular mechanisms involved in apoptotic signaling contributes to a vast range of oral diseases. An understanding of the regulation of apoptosis has led to the development of many therapeutic approaches and better management of oral diseases. The review updates us the correlation between apoptosis in normal oral tissues and oral diseases.
authors.affiliation: Department of Oral Pathology, Institute of Dental Studies and Technologies, Modinagar, Uttar Pradesh, India.
authors.forename: Akansha
authors.initials: A
authors.lastname: Misra
authors.affiliation: Department of Oral Medicine and Radiology, Institute of Dental Studies and Technologies, Modinagar, Uttar Pradesh, India.
authors.forename: Shalu
authors.initials: S
authors.lastname: Rai
authors.affiliation: Department of Oral Medicine and Radiology, Institute of Dental Studies and Technologies, Modinagar, Uttar Pradesh, India.
authors.forename: Deepankar
authors.initials: D
authors.lastname: Misra
keywords: Bax/B-cell lymphoma 2; caspase; death domain; precancer; programmed cell death; tumorigenesis