title: Click inspired synthesis of triazole-linked vanillin glycoconjugates.
abstract: The 1,3-dipolar cycloaddition of deoxy-azido sugars 1 with alkyne derivatives of p-vanillin, 3-methoxy-4-(prop-2-ynyloxy)benzaldehyde (2) and 2-methoxy-1-(prop-2-ynyloxy)-4-((prop-2-ynyloxy)methyl)benzene) (4) to afford regioselective triazole-linked vanillinglycoconjugates 5 and 6 was investigated in the presence of CuI/DIPEA in dichloromethane. All the developed glycoconjugates were characterized on the basis of IR, NMR, and MS. Graphical abstract Triazolyl vanillin glycoconjugates via click chemistry.
authors.affiliation: Department of Chemistry, Centre of Advanced Study, Faculty of Science, Banaras Hindu University, Varanasi, -221005, India.|Center of Innovative and Applied Bioprocessing (CIAB), C-127, IInd Floor, Phase VIII, Industrial Area, SAS Nagar, Mohali, Punab, -160071, India.
authors.forename: Pratibha
authors.initials: P
authors.lastname: Dwivedi
authors.affiliation: Department of Chemistry, Centre of Advanced Study, Faculty of Science, Banaras Hindu University, Varanasi, -221005, India.
authors.forename: Kunj B
authors.initials: KB
authors.lastname: Mishra
authors.affiliation: Center of Innovative and Applied Bioprocessing (CIAB), C-127, IInd Floor, Phase VIII, Industrial Area, SAS Nagar, Mohali, Punab, -160071, India.
authors.lastname: Pritika
authors.affiliation: Department of Chemistry, Centre of Advanced Study, Faculty of Science, Banaras Hindu University, Varanasi, -221005, India. bbmchem@gmail.com.|Center of Innovative and Applied Bioprocessing (CIAB), C-127, IInd Floor, Phase VIII, Industrial Area, SAS Nagar, Mohali, Punab, -160071, India. bbmchem@gmail.com.
authors.forename: Bhuwan B
authors.initials: BB
authors.lastname: Mishra
authors.affiliation: Department of Chemistry, Centre of Advanced Study, Faculty of Science, Banaras Hindu University, Varanasi, -221005, India. tiwari_chem@yahoo.co.in.
authors.forename: Vinod K
authors.initials: VK
authors.lastname: Tiwari
mesh_terms: D001547:Benzaldehydes / Q000737:chemistry*; D057930:Click Chemistry / Q000379:methods*; D006001:Glycoconjugates / Q000138:chemical synthesis* / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D001547:Benzaldehydes; D006001:Glycoconjugates; D006027:Glycosides; D014230:Triazoles; C100058:vanillin
keywords: Carbohydrates; Click chemistry; Glycoconjugates; Vanillin