title: Pyrexia of unknown origin in clinical practice.
abstract: This article revisits concepts of pyrexia of unknown origin to reflect current clinical practice. It describes the evolution of the term, in line with the changing spectrum and pace of investigations, and introduces key questions that may be used to evaluate a pyrexia of unknown origin.
authors.affiliation: Specialist Trainee and Academic Clinical Fellow in the Department of Infectious Diseases and Microbiology, Royal Free Hospital, London NW3 2QG.
authors.forename: Tehmina
authors.initials: T
authors.lastname: Bharucha
authors.affiliation: Academic Foundation Year 2 in the Department of Virology, Royal Free Hospital, London.
authors.forename: Beatrice
authors.initials: B
authors.lastname: Cockbain
authors.affiliation: Infectious Diseases Consultant in the Hospital for Tropical Diseases, University College London Hospital NHS Foundation Trust and Faculty of Infectious Diseases and Tropical Medicine London School of Hygiene and Tropical Medicine, London.
authors.forename: Michael
authors.initials: M
authors.lastname: Brown
mesh_terms: D005335:Fever of Unknown Origin / Q000209:etiology*; D006801:Humans; D007239:Infections / Q000150:complications*; D007249:Inflammation / Q000150:complications*; D009369:Neoplasms / Q000150:complications*