title: Overview of the Novel and Improved Pulmonary Ventilation-Perfusion Imaging Applications in the Era of SPECT/CT.
abstract: OBJECTIVE
  In this article, we describe the concepts of ventilation-perfusion planar, SPECT, and SPECT/CT and outline the advantages of integrated ventilation-perfusion SPECT/CT over planar imaging. We present an overview of the traditional and new applications of ventilation-perfusion scintigraphy.
  
  
  CONCLUSIONS
  SPECT/CT has improved the diagnostic accuracy of ventilation-perfusion imaging and opened the door for a new spectrum of applications.
authors.affiliation: 1 Department of Radiology, University of New Mexico, Albuquerque, NM.
authors.forename: Saeed
authors.initials: S
authors.lastname: Elojeimy
authors.affiliation: 2 Department of Radiology, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195.
authors.forename: Irene
authors.initials: I
authors.lastname: Cruite
authors.affiliation: 3 Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Bowen
authors.affiliation: 3 Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA.
authors.forename: Jing
authors.initials: J
authors.lastname: Zeng
authors.affiliation: 2 Department of Radiology, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195.
authors.forename: Hubert
authors.initials: H
authors.lastname: Vesselle
mesh_terms: D000280:Administration, Inhalation; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D015203:Reproducibility of Results; D012120:Respiration Disorders / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D000072098:Single Photon Emission Computed Tomography Computed Tomography / Q000295:instrumentation / Q000379:methods*; D014692:Ventilation-Perfusion Ratio
chemical_list: D019275:Radiopharmaceuticals
keywords: SPECT; SPECT/CT; perfusion; planar; pulmonary; ventilation