title: Iron(iii) chloride hexahydrate-promoted selective hydroxylation and chlorination of benzyl ketone derivatives for the construction of hetero-quaternary scaffolds.
abstract: A novel and tunable α-hydroxylation/α-chlorination of benzyl ketone derivatives has been developed for the construction of hetero-quaternary carbon centers by iron(iii) chloride hexahydrate mediated selective transformations through the application of different oxidants, especially the crystal water in the catalyst as an OH source is firstly reported in this hydroxylation.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, 730000, P.R. China. zhangfm@lzu.edu.cn.
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, 730000, P.R. China. zhangfm@lzu.edu.cn.
authors.forename: Rui
authors.initials: R
authors.lastname: Peng
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, 730000, P.R. China. zhangfm@lzu.edu.cn.
authors.forename: Wenxin
authors.initials: W
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou, 730000, P.R. China. zhangfm@lzu.edu.cn.
authors.forename: Fu-Min
authors.initials: FM
authors.lastname: Zhang
mesh_terms: D002712:Chlorides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D054879:Halogenation; D006900:Hydroxylation; D007659:Ketones / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D002712:Chlorides; D005290:Ferric Compounds; D007659:Ketones; D014867:Water; C024555:ferric chloride