title: Metastasis of colon cancer to the thyroid and cervical lymph nodes: a case report.
abstract: The incidence of thyroid metastasis among colorectal cancer patients is extremely rare. We report a case of colonic adenocarcinoma metastasis to the thyroid gland with treatment of lung and liver metastases, in a 61-year-old woman with a history of colon cancer. She showed a thyroid mass related to a 3-month history of hoarseness. Physical and imaging examinations disclosed a diffuse large thyroid mass with swollen cervical lymph nodes. Fine-needle aspiration cytology of the thyroid mass suggested malignancy. The patient underwent total thyroidectomy. Histopathological examination and immunohistochemical staining revealed adenocarcinoma, which was consistent with a diagnosis of metastases from primary colon cancer to the thyroid and cervical lymph nodes. At 2 years after thyroid surgery, the patient has been continuing outpatient chemotherapy for the lung and liver metastases. Thyroidectomy appeared to both relieve the patient and prevent local symptoms.
authors.affiliation: Department of Surgery, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan. shiminami-gi@umin.net.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Minami
authors.affiliation: Department of Surgery, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Inoue
authors.affiliation: Department of Pathology, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Junji
authors.initials: J
authors.lastname: Irie
authors.affiliation: Department of Clinical Oncology, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Mine
authors.affiliation: Department of Surgery, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tada
authors.affiliation: Department of Surgery, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Hirabaru
authors.affiliation: Department of Surgery, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Noda
authors.affiliation: Department of Surgery, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Ito
authors.affiliation: Department of Surgery, Nagasaki Harbor Medical Center City Hospital, 6-39 shinchi-machi, Nagasaki, 850-8555, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Haraguchi
keywords: Colon cancer; Metastasis; Thyroid