title: A case of rhino-orbital mucormycosis in diabetes with haematogenous cerebral spread.
abstract: We document the first case of haematogenous cerebral spread inRhizopus arrhizusrhino-orbital mucormycosis, and of posaconazole related adrenal insufficiency. A patient presenting with diabetic ketoacidosis and sinusitis was treated with right medial maxillectomy, ethmoidectomy and IV liposomal amphotericin. Orbital exenteration was performed after intraorbital spread of infection. IV caspofungin and posaconazole was added but complicated by adrenal insufficiency. MRI revealed a new left lentiform nucleus and thalamus rim-enhancing lesion indicating haematogenous cerebral spread.
authors.affiliation: Department of Diabetes and Endocrinology, Westmead Hospital, Westmead 2145, Australia.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Snaith
authors.affiliation: Department of Diabetes and Endocrinology, Westmead Hospital, Westmead 2145, Australia; Sydney Medical School, The University of Sydney, Sydney 2006, Australia.
authors.forename: Kharis
authors.initials: K
authors.lastname: Burns
authors.affiliation: Department of Infectious Diseases and Microbiology, Westmead Hospital, Westmead 2145, Australia.
authors.forename: Jen
authors.initials: J
authors.lastname: Kok
authors.affiliation: Sydney Medical School, The University of Sydney, Sydney 2006, Australia; Department of Infectious Diseases and Microbiology, Westmead Hospital, Westmead 2145, Australia.
authors.forename: Sharon
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Diabetes and Endocrinology, Westmead Hospital, Westmead 2145, Australia; Sydney Medical School, The University of Sydney, Sydney 2006, Australia.
authors.forename: N Wah
authors.initials: NW
authors.lastname: Cheung
keywords: Adrenal insufficiency; Diabetes; Diabetic ketoacidosis; Mucormycosis; Posaconazole