title: An extraordinary case of syphilis presenting with a labial ulcer.
abstract: In the differential diagnosis of patients with ulcers on the lips characteristics like the duration of the ulcer, number, size, depth, shape, base, margins, and distribution are considered. Such ulcers arise from many diseases particularly, viral and bacterial infections, malignancies can also be responsible. Classic syphilitic chancres are painless erosions settled on hard papule; these are evident in the genital area in more than 90% of patients. This study describes a case of a 38-year-old female patient presenting with a painful ulcer covering 3 quarters of the upper lip showing settlement on erythematous, edematous, and indurated plaque covered with hemorrhagic crusts. The aim of this study was to consider differences between the classic syphilitic chancre typically found in the genital region from extragenital chancres and to raise awareness of the possibility of primary syphilis when patients present with painful ulcers on the lip.
authors.affiliation: Department of Dermatology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey. E-mail. filizsvet@yahoo.com.
authors.forename: Filiz T
authors.initials: FT
authors.lastname: Demir
authors.forename: Kenyul
authors.initials: K
authors.lastname: Salaeva
authors.forename: Ilknur K
authors.initials: IK
authors.lastname: Altunay
authors.forename: Ozben
authors.initials: O
authors.lastname: Yalcın
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002081:Buttocks / Q000382:microbiology / Q000473:pathology; D002601:Chancre / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008047:Lip Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D010400:Penicillin G / Q000627:therapeutic use; D012725:Sexual Behavior; D013588:Syphilis Serodiagnosis / Q000379:methods; D016896:Treatment Outcome; D014210:Treponema pallidum / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G