title: Acute effects of aerobic exercise intensity on arterial stiffness after glucose ingestion in young men.
abstract: Arterial stiffness increases after glucose ingestion. Acute low- and moderate-intensity aerobic exercise decreases arterial stiffness. However, the acute effects of 30 min of cycling at low- and moderate-intensity [25% (LE trial) and 65% (ME trial) peak oxygen uptake, respectively] on arterial stiffness at 30, 60 and 120 min of a postexercise glucose ingestion. Ten healthy young men (age, 22·4 ± 0·5 years) performed LE and ME trials on separate days in a randomized controlled crossover fashion. Carotid-femoral (aortic) pulse wave velocity (PWV), femoral-ankle (leg) PWV, carotid augmentation index (AIx) and carotid blood pressure (BP) (applanation tonometry), brachial and ankle BP (oscillometric device), heart rate (HR) (electrocardiography), blood glucose (UV-hexokinase method) and blood insulin (CLEIA method) levels were measured at before (baseline) and at 30, 60 and 120 min after the 75-g OGTT. Leg PWV, ankle pulse pressure and BG levels significantly increased from baseline after the 75-g OGTT in the LE trial (P<0·05), but not in the ME trial. Insulin levels and HR significantly increased from baseline after the 75-g OGTT in both trials (P<0·05). Aortic PWV, carotid AIx, brachial BP and carotid BP did not change from baseline after the 75-g OGTT in both trials. The present findings indicate that aerobic exercise at moderate intensity before glucose ingestion suppresses increases leg arterial stiffness after glucose ingestion.
authors.affiliation: Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, Japan.
authors.forename: Ryota
authors.initials: R
authors.lastname: Kobayashi
authors.affiliation: Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, Japan.
authors.forename: Yuto
authors.initials: Y
authors.lastname: Hashimoto
authors.affiliation: Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hatakeyama
authors.affiliation: Department of Exercise Physiology, Nippon Sport Science University, Tokyo, Japan.
authors.forename: Takanobu
authors.initials: T
authors.lastname: Okamoto
mesh_terms: D000367:Age Factors; D055109:Ankle Brachial Index; D001786:Blood Glucose / Q000378:metabolism; D002339:Carotid Arteries / Q000502:physiology*; D018592:Cross-Over Studies; D015444:Exercise / Q000502:physiology*; D005947:Glucose / Q000008:administration & dosage* / Q000378:metabolism; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008365:Manometry; D009119:Muscle Contraction; D063177:Pulse Wave Analysis; D012737:Sex Factors; D013997:Time Factors; D059289:Vascular Stiffness; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D007328:Insulin; D005947:Glucose
keywords: acute aerobic exercise; blood glucose; exercise intensity; glucose ingestion; leg arterial stiffness