title: Cryptococcus gattii Genotype VGIIa Infection in an Immunocompetent Japanese Patient: A Case Report and Mini-review.
abstract: A 39-year-old man presented to our hospital with a four-week history of headache and a two-week history of low-grade fever. Chest X-rays showed a tumor of approximately 50 mm in size in the right lower field. A histopathological examination of a transbronchial lung biopsy specimen from the right S9/10 revealed numerous fungal elements that appeared as encapsulated yeast with clear halos. Gadolinium-enhanced brain magnetic resonance images showed multiple cerebral nodules. Cryptococcus gattii (Genotype VGIIa) was isolated from the bronchial lavage and cerebrospinal fluid specimens. The patient was an immunocompetent Japanese man who had not recently traveled to a C. gattii-endemic area.
authors.affiliation: Department of Respiratory Medicine, Kainan Hospital Aichi Prefectural Welfare Federation of Agricultural Cooperatives, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Nakao
authors.forename: Hideki
authors.initials: H
authors.lastname: Muramatsu
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Takahashi
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Niwa
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kagawa
authors.forename: Ryota
authors.initials: R
authors.lastname: Kurokawa
authors.forename: Kazuki
authors.initials: K
authors.lastname: Sone
authors.forename: Yuki
authors.initials: Y
authors.lastname: Uozumi
authors.forename: Misako
authors.initials: M
authors.lastname: Ohkusu
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Kamei
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Koga
mesh_terms: D000328:Adult; D003453:Cryptococcosis / Q000000981:diagnostic imaging* / Q000382:microbiology*; D056285:Cryptococcus gattii / Q000302:isolation & purification*; D006801:Humans; D007564:Japan; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed