title: Cobalt-Catalyzed Monoselective Ortho-C-H Functionalization of Carboxamides with Organoaluminum Reagent.
abstract: A simple triphenylphosphine-ligated cobalt catalyst is reported for the direct ortho-C-H methylation and ethylation of aromatic, heteroaromatic, alkenyl, and even aliphatic carboxamides with inexpensive organoaluminum reagents in the presence of a cheap alkyl chloride as oxidant. This reaction shows monoselectivity in contrast with previously established C-H methylation methodologies.
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang, Henan 473061, P. R. China.
authors.forename: Huiqiao
authors.initials: H
authors.lastname: Wang
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang, Henan 473061, P. R. China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang, Henan 473061, P. R. China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Wang
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang, Henan 473061, P. R. China.
authors.forename: Minghui
authors.initials: M
authors.lastname: He
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang, Henan 473061, P. R. China.
authors.forename: Kun
authors.initials: K
authors.lastname: Xu