title: Extramedullary Plasmacytoma of the Gallbladder Detected on Fluorine 18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.
abstract: Extramedullary plasmacytoma is rare in patients with diagnosed multiple myeloma. Soft tissue plasmacytoma of the gallbladder is particularly uncommon and has been described in only a handful of cases. Diagnosis of gallbladder plasmacytoma with fluorine 18-fluorodeoxyglucose (F18-FDG) positron emission tomography/computed tomography (PET/CT) has not previously been reported. We present a 65-year-old female with a history of multiple myeloma who underwent a restaging F18-FDG-PET/CT which showed a focal area of hypermetabolic activity, corresponding to a nodular lesion within the posterior gallbladder wall. The patient underwent successful cholecystectomy, with surgical pathology revealing gallbladder plasmacytoma. A follow-up scan was negative for active malignancy. This is a novel case of gallbladder plasmacytoma diagnosed on whole-body F18-FDG PET/CT - thus demonstrating the clinical value of this imaging modality in staging, restaging, and surveillance for patients with multiple myeloma.
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
authors.forename: Asif Ali
authors.initials: AA
authors.lastname: Fakhri
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
authors.forename: Paul David
authors.initials: PD
authors.lastname: Rodrigue
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
authors.forename: Amena Fatima
authors.initials: AF
authors.lastname: Fakhri
keywords: Gallbladder; fluorine 18-fluorodeoxyglucose positron emission tomography/computed tomography; plasmacytoma