title: Two-year clinical outcomes in stable angina and acute coronary syndrome after percutaneous coronary intervention of left main coronary artery disease.
abstract: OBJECTIVE
  This study appraised the long term clinical outcomes of patients treated with percutaneous coronary intervention (PCI) for unprotected left main coronary artery (ULMCA) disease. There are limited data regarding long-term clinical outcomes after PCI for ULMCA disease.
  
  
  METHODS
  From 2001 to 2011, a total of 448 patients who underwent PCI for ULMCA disease and had 2-year clinical follow-up, were analyzed. The study patients were divided into two groups: group I (stable angina pectoris [SAP], n = 60, 48 men, 62 ± 10 years) and group II (acute coronary syndrome [ACS], n = 388, 291 men, 64 ± 10 years). We evaluated clinical and angiographic characteristics and major adverse cardiac events (MACE) during 2-year clinical follow-up.
  
  
  RESULTS
  Mean age of studied patients was 64 ± 10 years with 339 male patients. Average stent diameter was 3.6 ± 0.4 mm and stent length was 19.7 ± 6.3 mm. Stent implantation techniques and use of intravascular ultrasound guidance were not different between two groups. In-hospital mortality was 0% in group I and 7% in group II (p= 0.035). One-month mortality was 0% in group I and 7.7% in group II (p= 0.968). Two-year survival rate was 93% in the group I and 88.4% in the group II (p= 0.921). Predictive factors for 2-year MACE were hypertension, Killip class ≥ 3, and use of intra-aortic balloon pump by multivariate analysis.
  
  
  CONCLUSIONS
  Although in-hospital mortality rate was higher in ACS than in SAP, clinical outcomes during 2-year clinical follow-up were similar between SAP and ACS after PCI of ULMCA.
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Dae Young
authors.initials: DY
authors.lastname: Hyun
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Myung Ho
authors.initials: MH
authors.lastname: Jeong
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Doo Sun
authors.initials: DS
authors.lastname: Sim
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Yun Ah
authors.initials: YA
authors.lastname: Jeong
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Kyung Hoon
authors.initials: KH
authors.lastname: Cho
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Min Chul
authors.initials: MC
authors.lastname: Kim
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Hyun Kuk
authors.initials: HK
authors.lastname: Kim
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Hae Chang
authors.initials: HC
authors.lastname: Jeong
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Keun Ho
authors.initials: KH
authors.lastname: Park
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Young Joon
authors.initials: YJ
authors.lastname: Hong
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Jun Han
authors.initials: JH
authors.lastname: Kim
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Youngkeun
authors.initials: Y
authors.lastname: Ahn
authors.affiliation: The Heart Center of Chonnam National University Hospital and The Heart Research Center Nominated by Korea Ministry of Health and Welfare, Gwangju, Korea.
authors.forename: Jung Chaee
authors.initials: JC
authors.lastname: Kang
mesh_terms: D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D000368:Aged; D060050:Angina, Stable / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D018450:Disease Progression; D018572:Disease-Free Survival; D054855:Drug-Eluting Stents; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007423:Intra-Aortic Balloon Pumping / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D016016:Proportional Hazards Models; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
keywords: Coronary artery disease; Left main stem; Percutaneous coronary intervention