title: Effect of whitening dentifrices: a double-blind randomized controlled trial.
abstract: The aim of this clinical study was to evaluate tooth color changes (ΔE) and tooth sensitivity (TS) associated with whitening dentifrices. Sixty participants were selected according to inclusion and exclusion criteria and then allocated to three groups (n = 20): Colgate Luminous White (G1), Close Up White Now (G2) and Sorriso dentifrice (G3-control). The participants were instructed to use only the provided dentifrice and toothbrush in standardized oral hygiene procedures for 4 weeks. ΔE was assessed by spectrophotometry (CIELab System) whereas TS was determined by a visual analog scale at baseline and weekly using four assessment points. The data were analyzed by two-way ANOVA and Tukey's post-hoc test and Friedman test (α = 0.05). ΔE (baseline-assessment point 4) showed no significant difference (p>0.05) across the groups: G1 (ΔE = 5.1), G2 (ΔE = 6.8), and G3 (ΔE = 4.4). Δb (baseline-assessment point 4) was significantly different (p < 0.05) in G2 (3.8) when compared to G1 (-0.2) and G3 (0.3). There was no significant difference (p > 0.05) in TS at baseline. Both the control and whitening dentifrices caused similar tooth color changes (ΔE). There was no significant TS during the study period.
authors.affiliation: Universidade de São Paulo (USP), School of Dentistry of Ribeirão Preto, Department of Dental Materials and Prosthodontics, Ribeirão Preto, SP, Brazil.
authors.forename: Karen
authors.initials: K
authors.lastname: Pintado-Palomino
authors.affiliation: Universidade de São Paulo (USP), School of Dentistry of Ribeirão Preto, Department of Dental Materials and Prosthodontics, Ribeirão Preto, SP, Brazil.
authors.forename: Cecília Vilela Matias
authors.initials: CV
authors.lastname: Vasconcelos
authors.affiliation: Universidade de São Paulo (USP), School of Dentistry of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
authors.forename: Roberto Juns da
authors.initials: RJ
authors.lastname: Silva
authors.affiliation: Universidade de São Paulo (USP), School of Dentistry of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
authors.forename: Andre Luiz de Macedo
authors.initials: AL
authors.lastname: Fressatti
authors.affiliation: Universidade de São Paulo (USP), School of Dentistry of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
authors.forename: Bianka Jurca Gonçalves da
authors.initials: BJ
authors.lastname: Motta
authors.affiliation: Universidade de São Paulo (USP), School of Dentistry of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
authors.forename: Fernanda de Carvalho Panzeri
authors.initials: FC
authors.lastname: Pires-DE-Souza
authors.affiliation: Universidade de São Paulo (USP), School of Dentistry of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
authors.forename: Camila
authors.initials: C
authors.lastname: Tirapelli
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003116:Color; D003802:Dentifrices / Q000009:adverse effects / Q000494:pharmacology*; D003807:Dentin Sensitivity / Q000139:chemically induced*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D013053:Spectrophotometry; D013997:Time Factors; D014073:Tooth Bleaching / Q000379:methods*; D058205:Tooth Bleaching Agents / Q000009:adverse effects / Q000494:pharmacology*; D016896:Treatment Outcome; D064232:Visual Analog Scale
chemical_list: D003802:Dentifrices; D058205:Tooth Bleaching Agents