title: Neoatherosclerosis causing occlusive in-stent restenosis: Impact of intracoronary imaging in the intensity of lipid-lowering therapy.
abstract: The unique physical properties of optical coherence tomography (OCT) make it a useful technique in the study of restenosis mechanisms. In fact, OCT is able to differentiate between neointimal proliferation and neoatherosclerosis within the stent. We report a rare case of occlusive neoatherosclerosis presenting beyond one year after a successful drug-eluting stent implantation. The impact of OCT findings in the clinical decision making process is emphasized.
authors.affiliation: Department of Cardiology, Hospital Central de la Defensa, Madrid, Spain. Electronic address: docalcala@hotmail.com.
authors.forename: David
authors.initials: D
authors.lastname: Martí
authors.affiliation: Department of Cardiology, Hospital Central de la Defensa, Madrid, Spain.
authors.forename: Edurne
authors.initials: E
authors.lastname: López
authors.affiliation: Department of Cardiology, Hospital Central de la Defensa, Madrid, Spain.
authors.forename: Salvador
authors.initials: S
authors.lastname: Álvarez
authors.affiliation: Department of Cardiology, Hospital Central de la Defensa, Madrid, Spain.
authors.forename: Jorge
authors.initials: J
authors.lastname: Palazuelos
authors.affiliation: Department of Cardiology, Hospital Central de la Defensa, Madrid, Spain.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Rada
authors.affiliation: Department of Cardiology, Hospital Universitario de La Princesa, Madrid, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Alfonso
mesh_terms: D000368:Aged; D002317:Cardiovascular Agents / Q000008:administration & dosage; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D054059:Coronary Occlusion / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D054855:Drug-Eluting Stents; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000295:instrumentation*; D058226:Plaque, Atherosclerotic; D019233:Retreatment; D020123:Sirolimus / Q000008:administration & dosage / Q000031:analogs & derivatives; D015607:Stents; D013997:Time Factors; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents; D000960:Hypolipidemic Agents; C518022:umirolimus; D020123:Sirolimus
keywords: In-stent restenosis; Neoatherosclerosis; Optical coherence tomography