title: Physical Activity and Kidney Injury in Pediatric and Young Adult Kidney Transplant Recipients.
abstract: To quantify physical activity and grip strength in pediatric kidney transplant recipients and describe attitudes about exercise and exercise counseling given concerns about allograft injury.
  
  
  
  This was a cross-sectional analysis of 101 kidney transplant recipients (7-21 years old) >6 months post-transplant. Patients completed the Physical Activity Questionnaire (PAQ). Grip strength was measured with a dynamometer. We asked about activity limitations and provider counseling. Univariate analysis and multiple linear regression were used to determine independent predictors of PAQ score and grip strength z score.
  
  
  
  We enrolled 101 of 122 eligible patients. Median PAQ score was 2.2 (range 0-5) and was lower compared with controls (P < .001). The average grip strength z score was -1.1 and -0.7 in the right and left hand, respectively. Predictors of lower grip strength were younger age (P = .036), non-African American race (P = .029), lower height z score (P = .010), and longer percentage of lifetime with kidney disease (P = .029). Although 49% and 67% limited exercise before and after transplant, respectively, 67% reported increased activity after transplant. By parent report, provider counseling included limiting certain activities (71%) and encouraging regular exercise (45%).
  
  
  
  Physical activity and grip strength are low after kidney transplant. Patients perceive an emphasis on exercise limitations rather than the benefits of regular exercise. Interventions that encourage physical activity may be beneficial.
authors.affiliation: Emory University School of Medicine, Atlanta, GA.
authors.forename: Mattie F
authors.initials: MF
authors.lastname: Wolf
authors.affiliation: Emory University School of Medicine, Atlanta, GA; Children's Healthcare of Atlanta, Atlanta, GA.
authors.forename: Roshan P
authors.initials: RP
authors.lastname: George
authors.affiliation: Emory University School of Medicine, Atlanta, GA; Children's Healthcare of Atlanta, Atlanta, GA.
authors.forename: Barry
authors.initials: B
authors.lastname: Warshaw
authors.affiliation: Emory University School of Medicine, Atlanta, GA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Wang
authors.affiliation: Emory University School of Medicine, Atlanta, GA; Children's Healthcare of Atlanta, Atlanta, GA. Electronic address: Lgreen6@emory.edu.
authors.forename: Larry A
authors.initials: LA
authors.lastname: Greenbaum
mesh_terms: D000293:Adolescent; D001265:Athletic Injuries / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D015444:Exercise; D005260:Female; D018737:Hand Strength; D006801:Humans; D007668:Kidney / Q000293:injuries*; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology*; D051436:Renal Insufficiency, Chronic / Q000503:physiopathology* / Q000601:surgery*; D055815:Young Adult
keywords: cardiovascular disease; chronic kidney disease; exercise; grip strength