title: Congenital bronchopulmonary malformation: CT histopathological correlation.
abstract: BACKGROUND
  This study evaluated the accuracy of postnatal computed tomography (CT) imaging in the identification of congenital bronchopulmonary malformation (BPM) in comparison with histopathological analysis.
  
  
  METHODS
  CT scans of prenatally diagnosed BPMs from 24 patients with available histology were analysed retrospectively. The CT images were reviewed blinded to histological findings by two radiologists. Specific diagnosis was assigned based on predetermined criteria. The accuracy of CT was evaluated.
  
  
  RESULTS
  The agreement rate in CT diagnosis between two radiologists was 100%. In 75% the lesions were located in the lower lobes. An overlap of 71% in CT and histopathological diagnoses was reached. The least matching diagnosis was type 2 CPAM.
  
  
  CONCLUSIONS
  Contrast enhanced chest CT is very accurate in characterizing the BPM spectrum and provides important information on lesion type and structure.
authors.affiliation: Department of Radiology, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
authors.forename: Martin
authors.initials: M
authors.lastname: Kyncl
authors.affiliation: Department of Radiology, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
authors.forename: Martin
authors.initials: M
authors.lastname: Koci
authors.affiliation: Department of Radiology, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
authors.forename: Lea
authors.initials: L
authors.lastname: Ptackova
authors.affiliation: Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
authors.forename: Ludmila
authors.initials: L
authors.lastname: Hornofova
authors.affiliation: Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
authors.forename: Fabian
authors.initials: F
authors.lastname: Ondrej
authors.affiliation: Department of Paediatric Surgery, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
authors.forename: Jiri
authors.initials: J
authors.lastname: Snajdauf
authors.affiliation: Department of Paediatric Surgery, 2nd Faculty of Medicine, Charles University in Prague and Faculty Hospital Motol, Prague, Czech Republic.
authors.forename: Marcela
authors.initials: M
authors.lastname: Pychova
mesh_terms: D002675:Child, Preschool; D003287:Contrast Media; D005260:Female; D006801:Humans; D007223:Infant; D008168:Lung / Q000002:abnormalities* / Q000000981:diagnostic imaging; D008297:Male; D015619:Respiratory System Abnormalities / Q000000981:diagnostic imaging / Q000473:pathology; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000592:standards*
chemical_list: D003287:Contrast Media
keywords: bronchopulmonary malformation; computed tomography; histopathological findings; predetermined criteria