title: Seroprevalence of Toxoplasma gondii Among Pregnant Women in Northeast India.
abstract: Toxoplasma gondii infection is primarily asymptomatic and one third of world's population is estimated to be infected by this protozoan parasite. This study was carried out to determine the seroprevalence of T. gondii infection among pregnant women from north east India, where data on this important parasitic infection is scanty.
  
  
  
  A total of 1141 serum archival samples collected from antenatal clinic attendees in 2007-09, were screened for T. gondii IgG by ELISA and analyzed with their socio demographic information.
  
  
  
  The median age of the subjects were 25 years with an overall IgG seroprevalence of 48% (95% CI=45% to 51%). Seroprevalence was significantly associated with geographical location (p=0.000), among Mongoloids compared to Caucasoid (p=0.005), regular employees (p=0.003) or unskilled labors (p=0.04) compared to housewives, high or middle income group (p=0.003) compared to low income group and with increasing gravida (p=0.04). However on logistic regression analysis, only significant association was with geographical location (p=0.000) and occupation (unskilled labor) (p=0.04). Highest prevalence of 66.7% was noted among subjects with history of blood transfusion and lowest among Rh negative blood group (14.3%).
  
  
  
  T. gondii infection prevalence is high among pregnant women living in hilly states of northeast India, which warrants a detail investigation on congenital toxoplasmosis as well as its economic impact.
authors.affiliation: Scientist D.
authors.forename: Biswajyoti
authors.initials: B
authors.lastname: Borkakoty
authors.affiliation: Scientist E.
authors.forename: Dipankar
authors.initials: D
authors.lastname: Biswas
authors.affiliation: Scientist C.
authors.forename: Aniruddha
authors.initials: A
authors.lastname: Jakharia
authors.affiliation: Distinguished Scientist Chair, Regional Medical Research Centre for NE Region (ICMR), Dibrugarh, Assam.
authors.forename: Jagadish
authors.initials: J
authors.lastname: Mahanta
mesh_terms: D000293:Adolescent; D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007194:India / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood* / Q000453:epidemiology*; D012189:Retrospective Studies; D016036:Seroepidemiologic Studies; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000097:blood* / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G