title: Plugged percutaneous biopsy of the liver in living-donor liver transplantation recipients suspected to have graft rejection.
abstract: Background Percutaneous biopsy is a widely-accepted technique for acquiring histologic samples of the liver. When there is concern for bleeding, plugged percutaneous biopsy (PPB) may be performed, which involves embolization of the biopsy tract. Purpose To evaluate the efficacy and safety of PPB of the liver in patients suspected to have graft rejection after living-donor liver transplantation (LDLT). Material and Methods During January 2007 and December 2013, 51 patients who underwent PPB of the liver under the suspicion of post-LDLT graft rejection were retrospectively analyzed. A total of 73 biopsies were performed. Biopsy was performed with a 17-gauge core needle and 18-gauge cutting needle. The needle tract was embolized using gelatin sponge (n = 44) or N-butyl cyanoacrylate (NBCA) (n = 29). The specimens were reviewed to determine their adequacy for histologic diagnosis. We reviewed all medical records after PPB. Results Specimens were successfully acquired in all procedures (100%). They were adequate for diagnosis in 70 cases (95.9%) and inadequate in three (1.3%). Average of 9.8 complete portal tracts was counted per specimen. One minor complication (1.4%) occurred where the patient had transient fever after the procedure. Conclusion PPB is easy and safe to perform in LDLT recipients and provides high diagnostic yield.
authors.affiliation: 1 Department of Radiology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Sung Jung
authors.initials: SJ
authors.lastname: Kim
authors.affiliation: 1 Department of Radiology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Je Hwan
authors.initials: JH
authors.lastname: Won
authors.affiliation: 2 Department of Pathology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Young Bae
authors.initials: YB
authors.lastname: Kim
authors.affiliation: 3 Department of Hepatobiliary Surgery and Liver Transplantation, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Hee-Jung
authors.initials: HJ
authors.lastname: Wang
authors.affiliation: 3 Department of Hepatobiliary Surgery and Liver Transplantation, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Bong-Wan
authors.initials: BW
authors.lastname: Kim
authors.affiliation: 4 Department of Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
authors.forename: Haeryoung
authors.initials: H
authors.lastname: Kim
authors.affiliation: 1 Department of Radiology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Jinoo
authors.initials: J
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000009:adverse effects / Q000379:methods; D002648:Child; D002675:Child, Preschool; D004621:Embolization, Therapeutic; D005260:Female; D006084:Graft Rejection / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
keywords: Liver; image-guided biopsy; interventional; liver transplantation; living donors; radiology