title: Frenchay dysarthria assessment (FDA-2) in Parkinson's disease: cross-cultural adaptation and psychometric properties of the European Portuguese version.
abstract: Hypokinetic dysarthria is a common symptom in those with Parkinson's disease (PD); there is currently no standardized or validated tool for assessing speech in this population. To translate into European Portuguese (EP) the FDA-2 and perform a cultural adaptation followed by an evaluation of its psychometric properties in PD in a sample of people with PD in different stages of disease progression. Translation, back-translation, experts' analysis, pre-test and final version test were performed. The EP version of the FDA-2 was administered to 80 people with PD (PwP) with dysarthria, feasibility and acceptability, reliability (internal consistency and inter-rater reliability) and validity (face and convergent) were measured. Overall, the EP-FDA-2 proved to be similar to the original demonstrating the same conceptual meanings, semantics, idiomatic and score equivalences. It has good feasibility (missing data <5 %), acceptability (ceiling and floor effects <15 %), a high reliability of the total score (0.94), an excellent inter-rater agreement for the total score (0.96) and moderate to large construct validity for 81 % of its items. It is well correlated with the gold standard for disease severity assessment in PD, the MDS-UPDRS. The EP-FDA-2 has shown the salient features of a valid tool that can be used by speech and language therapists in the assessment of dysarthria in PD in clinical practice as in the research field.
authors.affiliation: Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.|Campus Neurológico Sénior, Torres Vedras, Portugal.
authors.forename: Rita
authors.initials: R
authors.lastname: Cardoso
authors.affiliation: Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.|Department of Speech Therapy, Escola superior de Saúde de Alcoitão, Estoril, Portugal.
authors.forename: Isabel
authors.initials: I
authors.lastname: Guimarães
authors.affiliation: Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.|Campus Neurológico Sénior, Torres Vedras, Portugal.
authors.forename: Helena
authors.initials: H
authors.lastname: Santos
authors.affiliation: Campus Neurológico Sénior, Torres Vedras, Portugal.
authors.forename: Rita
authors.initials: R
authors.lastname: Loureiro
authors.affiliation: Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.|Campus Neurológico Sénior, Torres Vedras, Portugal.
authors.forename: Josefa
authors.initials: J
authors.lastname: Domingos
authors.affiliation: Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
authors.forename: Daisy
authors.initials: D
authors.lastname: de Abreu
authors.affiliation: Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
authors.forename: Nilza
authors.initials: N
authors.lastname: Gonçalves
authors.affiliation: Aix-Marseille Université/CNRS, Laboratoire Parole et Language (LPL), Aix-en-Provence, France.
authors.forename: Serge
authors.initials: S
authors.lastname: Pinto
authors.affiliation: Clinical Pharmacological Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal. joaquimjferreira@gmail.com.|Campus Neurológico Sénior, Torres Vedras, Portugal. joaquimjferreira@gmail.com.
authors.forename: Joaquim
authors.initials: J
authors.lastname: Ferreira
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003431:Cross-Cultural Comparison; D018450:Disease Progression; D004401:Dysarthria / Q000175:diagnosis* / Q000209:etiology*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010300:Parkinson Disease / Q000150:complications* / Q000175:diagnosis*; D011174:Portugal; D011594:Psychometrics; D015203:Reproducibility of Results; D014175:Translating
keywords: Dysarthria; Parkinsonism; Parkinson’s disease; Scale; Speech