title: Trigemino-Cervical Neuropathic Pain Relieved by Serially Repeated Peripheral Nerve Field Stimulation Without Tolerance: Case Report.
abstract: BACKGROUND
  With its relative simplicity and safety, peripheral nerve field stimulation (PNFS; PENS) is contributing to the re-emergence of peripheral nerve stimulation as an effective therapy for neuropathic pain (NPP).
  
  
  METHODS
  A 70-year-old woman had developed severe, medically refractory NPP unilaterally in the scalp and face 20 years earlier, following a maxillofacial surgical procedure. PNFS gave substantial relief of the pain and allodynia and was repeated successfully on a further 25 occasions over the subsequent five years. Tolerance did not develop.
  
  
  CONCLUSIONS
  Serially repeated PNFS can provide sustained relief of NPP over long periods, without tolerance, where a permanent implant may be inappropriate, unavailable, or declined.
authors.affiliation: Department of Neurosurgery, University Hospital of Wales, Cardiff, CF14 4XW, UK.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Simpson
authors.affiliation: Department of Neurosurgery, University Hospital of Wales, Cardiff, CF14 4XW, UK.
authors.forename: Ravindra
authors.initials: R
authors.lastname: Nannapaneni
mesh_terms: D000368:Aged; D005157:Facial Pain / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D009437:Neuralgia / Q000175:diagnosis / Q000628:therapy*; D010525:Peripheral Nerves / Q000473:pathology; D004561:Transcutaneous Electric Nerve Stimulation / Q000379:methods*; D016896:Treatment Outcome; D014276:Trigeminal Nerve / Q000473:pathology*
keywords: Allodynia; neuropathic pain; peripheral nerve field stimulation; tolerance; trigeminopathic pain