title: Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound.
abstract: Introduction. A number of studies suggest that oxygen-ozone therapy may have a role in the treatment of chronic, nonhealing, or ischemic wounds for its disinfectant and antibacterial properties. Nonhealing wounds are a significant cause of morbidity. Here we present a case of subcutaneous oxygen-ozone therapy used to treat a nonhealing postoperative wound in a young man during a period of 5 weeks.Case Presentation. A 46-year-old man had a motorcycle accident and underwent amputation of the right tibia and fibula. At the discharge he came to our attention to start rehabilitation treatment. At that time the wound was ulcerated but it was afebrile with no signs of inflammation and negativity to blood tests. At 2 months from the trauma despite appropriate treatment and dressing, the wound was slowly improving and the patient complained of pain. For this reason in addition to standard dressing he underwent oxygen-ozone therapy. After 5 weeks of treatment the wound had healed.Conclusion. In patients with nonhealing wounds, oxygen-ozone therapy could be helpful in speeding the healing and reducing the pain thanks to its disinfectant property and by the increase of endogenous oxygen free radicals' scavenging properties. Compared to standard dressing and other treatments reported in the literature it showed a shorter time of action.
authors.affiliation: Rehabilitation Unit, Azienda di Servizi alla Persona di Pavia, 27100 Pavia, Italy.
authors.forename: Irene
authors.initials: I
authors.lastname: Degli Agosti
authors.affiliation: Rehabilitation Unit, Azienda di Servizi alla Persona di Pavia, 27100 Pavia, Italy.
authors.forename: Elena
authors.identifier: 0000-0003-2693-2669
authors.initials: E
authors.lastname: Ginelli
authors.affiliation: Rehabilitation Unit, Azienda di Servizi alla Persona di Pavia, 27100 Pavia, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Mazzacane
authors.affiliation: Department of Public Health, Experimental and Forensic Medicine, School of Medicine, Endocrinology and Nutrition Unit, University of Pavia, Pavia, Italy.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Peroni
authors.affiliation: Section of Geriatrics, Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy.
authors.forename: Sandra
authors.initials: S
authors.lastname: Bianco
authors.affiliation: Section of Geriatrics, Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Guerriero
authors.affiliation: Section of Geriatrics, Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Ricevuti
authors.affiliation: Department of Public Health, Experimental and Forensic Medicine, School of Medicine, Endocrinology and Nutrition Unit, University of Pavia, Pavia, Italy.
authors.forename: Simone
authors.identifier: 0000-0002-2720-1473
authors.initials: S
authors.lastname: Perna
authors.affiliation: Department of Public Health, Experimental and Forensic Medicine, School of Medicine, Endocrinology and Nutrition Unit, University of Pavia, Pavia, Italy.
authors.forename: Mariangela
authors.identifier: 0000-0001-8336-4851
authors.initials: M
authors.lastname: Rondanelli