title: A comparative study of Sterofundin and Ringer lactate based infusion protocol in scoliosis correction surgery.
abstract: BACKGROUND
  A major change in anesthesia practice as regards to intraoperative infusion therapy is the present requirement. Switching over to balanced fluids can substantially decrease the incidence of lactic acidosis and hyperchloremic acidosis. The deleterious effects of unbalanced fluids are more recognizable during major surgeries. We prospectively studied the influence of Sterofundin (SF) and Ringer lactate (RL) on acid-base changes, hemodynamics, and readiness for extubation during scoliosis surgery.
  
  
  METHODS
  Thirty consecutive children posted for scoliosis surgery were randomized to receive either RL (n= 15) or SF (n= 15) as intraoperative fluid at 10 mg/kg/h. Fluid boluses were added according to the study fluid algorithm. Arterial blood was sampled and analyzed at hourly intervals during surgery. Red blood cell transfusion was guided by hematocrit below 27. Patients were followed for 24 h postoperatively in the Intensive Care Unit.
  
  
  RESULTS
  There was no statistically significant difference in the volume of infused fluid (2400 ± 512 ml in Group RL and 2200 ± 640 ml in Group SF. There were no significant changes in pH of patients infused with SF. Statistically, significant higher lactate levels were seen in RL-infused group. The strong ion difference was decreased in both groups, but it normalized earlier with SF.
  
  
  CONCLUSIONS
  SF-infused patients had nonremarkable changes in acid-base physiology in scoliosis surgery.
authors.affiliation: Department of Anesthesiology and Intensive Care, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
authors.forename: Ashima
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Anesthesiology and Intensive Care, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
authors.forename: Monu
authors.initials: M
authors.lastname: Yadav
authors.affiliation: Department of Anesthesiology and Intensive Care, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
authors.forename: B Rajesh
authors.initials: BR
authors.lastname: Kumar
authors.affiliation: Department of Anesthesiology and Intensive Care, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
authors.forename: P Sai
authors.initials: PS
authors.lastname: Lakshman
authors.affiliation: Department of Orthopedics, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
authors.forename: Raju
authors.initials: R
authors.lastname: Iyenger
authors.affiliation: Department of Anesthesiology and Intensive Care, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
authors.forename: Gopinath
authors.initials: G
authors.lastname: Ramchandran
keywords: Balanced; fluids; scoliosis; surgery