title: The application of neuroimaging to social inequity and language disparity: A cautionary examination.
abstract: In the nascent field of the cognitive neuroscience of socioeconomic status (SES), researchers are using neuroimaging to examine how growing up in poverty affects children's neurocognitive development, particularly their language abilities. In this review we highlight difficulties inherent in the frequent use of reverse inference to interpret SES-related abnormalities in brain regions that support language. While there is growing evidence suggesting that SES moderates children's developing brain structure and function, no studies to date have elucidated explicitly how these neural findings are related to variations in children's language abilities, or precisely what it is about SES that underlies or contributes to these differences. This issue is complicated by the fact that SES is confounded with such linguistic factors as cultural language use, first language, and bilingualism. Thus, SES-associated differences in brain regions that support language may not necessarily indicate differences in neurocognitive abilities. In this review we consider the multidimensionality of SES, discuss studies that have found SES-related differences in structure and function in brain regions that support language, and suggest future directions for studies in the area of cognitive neuroscience of SES that are less reliant on reverse inference.
authors.affiliation: Department of Psychology, Stanford University, Stanford, CA 94305, USA. Electronic address: mellwoodlowe@stanford.edu.
authors.forename: Monica E
authors.initials: ME
authors.lastname: Ellwood-Lowe
authors.affiliation: Department of Psychology, Stanford University, Stanford, CA 94305, USA; Neurosciences Program, Stanford University, Stanford, CA 94305, USA.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Sacchet
authors.affiliation: Department of Psychology, Stanford University, Stanford, CA 94305, USA; Neurosciences Program, Stanford University, Stanford, CA 94305, USA.
authors.forename: Ian H
authors.initials: IH
authors.lastname: Gotlib
mesh_terms: D001076:Aptitude / Q000502:physiology; D001921:Brain / Q000254:growth & development*; D002648:Child; D002657:Child Development / Q000502:physiology*; D002675:Child, Preschool; D003467:Cultural Deprivation; D005260:Female; D006801:Humans; D007802:Language; D007804:Language Development; D008297:Male; D019303:Multilingualism; D059906:Neuroimaging / Q000639:trends*; D012923:Social Class
keywords: Childhood poverty; Development; Language; Neuroimaging; Reverse inference; Socioeconomic status (SES)