title: [Current diagnostics and therapy recommendations for ocular basal cell carcinoma].
abstract: The treatment options for basal cell carcinoma (BCC) have recently been augmented with the introduction of novel chemotherapeutic drugs. New S2 guidelines on the disease have also been published. The aim of this article is to present a comprehensive state of the art description of the features of ocular BCC and an overview of the various therapeutic options. Particular emphasis is placed on the clinical signs, the diagnostic tools to identify periocular BCC and interpretation of the different histopathological subtypes. Tumor staging, TNM classification, interdisciplinary tumor conference reviews as well as psycho-oncological services play an important role in patients with pronounced periocular BCC. Surgical removal with a histological R0 resection is an important component of therapy options in this disease and includes the microsurgical excision into healthy tissue and the subsequent covering of the defect. A special focus of this article is the treatment of locally extensive and metastasized BCC.
authors.affiliation: Augenklinik - Universitätsklinikum Knappschaftskrankenhaus Bochum, Ruhr-Universität Bochum, In der Schornau 23-25, 44892, Bochum, Deutschland. vk@rub.de.
authors.forename: V
authors.initials: V
authors.lastname: Kakkassery
authors.affiliation: Augenklinik, Universitätsklinikum Bonn, Bonn, Deutschland.
authors.forename: K U
authors.initials: KU
authors.lastname: Loeffler
authors.affiliation: Klinik für Dermatologie, Venerologie und Allergologie - St. Josef-Hospital, Ruhr-Universität Bochum, Bochum, Deutschland.|Klinik für Plastische Chirurgie, Katholische Kliniken, Ruhrhalbinsel Essen, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Sand
authors.affiliation: Zentrum für Augenheilkunde, Universitätsklinikum zu Köln, Köln, Deutschland.
authors.forename: K R
authors.initials: KR
authors.lastname: Koch
authors.affiliation: Zentrum für Augenheilkunde, Universitätsklinikum zu Köln, Köln, Deutschland.
authors.forename: A M
authors.initials: AM
authors.lastname: Lentzsch
authors.affiliation: Institut für Pathologie, Ruhr-Universität Bochum, Bochum, Deutschland.
authors.forename: A C
authors.initials: AC
authors.lastname: Nick
authors.affiliation: Radio-Onkologie, Ruhr-Universität Bochum, Bochum, Deutschland.
authors.forename: I A
authors.initials: IA
authors.lastname: Adamietz
authors.affiliation: Zentrum für Augenheilkunde, Universitätsklinikum zu Köln, Köln, Deutschland.
authors.forename: L M
authors.initials: LM
authors.lastname: Heindl
mesh_terms: D002280:Basal Cell Carcinoma / Q000175:diagnosis* / Q000628:therapy*; D062109:Dermatologic Surgical Procedures / Q000592:standards; D019317:Evidence-Based Medicine; D005134:Eye Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008495:Medical Oncology / Q000592:standards*; D008866:Microsurgery / Q000592:standards; D013508:Ophthalmologic Surgical Procedures / Q000592:standards; D009885:Ophthalmology / Q000592:standards*; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome
keywords: Chemotherapeutic drugs; Histology; Microsurgery; Pathology; Tumors