title: Anaemia with inflammation responding to lenalidomide.
abstract: We present a case of a 73-year-old woman with transfusion-dependent anaemia thought to be secondary to an unidentifiable inflammatory condition. Anaemia evaluation including multiple bone marrow biopsies was unrevealing, with the exception of a non-specific elevation of her erythrocyte sedimentation rate and C-reactive protein. She had no identifiable inflammatory condition and did not meet the criteria for myelodysplastic syndrome. She was empirically treated with lenalidomide and achieved a complete response, suggesting that this immunomodulatory drug could potentially have a role in treating a subgroup of patients with immune-mediated anaemia.
authors.affiliation: Division of Hematology & Oncology, George Washington University Hospital, Washington DC, USA.
authors.forename: Faysal
authors.initials: F
authors.lastname: Haroun
authors.affiliation: Division of Hematology & Oncology, George Washington University Hospital, Washington DC, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Mener
authors.affiliation: George Washington University, School of Medicine and Health Sciences, Washington DC, USA.
authors.forename: Jacob
authors.initials: J
authors.lastname: Elkon
authors.affiliation: Division of Hematology & Oncology, George Washington University Hospital, Washington DC, USA.
authors.forename: Imad
authors.initials: I
authors.lastname: Tabbara
mesh_terms: D000368:Aged; D000740:Anemia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D007249:Inflammation / Q000209:etiology*; D000077269:Lenalidomide; D013792:Thalidomide / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D007155:Immunologic Factors; D013792:Thalidomide; D000077269:Lenalidomide