title: Chemical Components and Pharmacological Activities of Terpene Natural Products from the Genus Paeonia.
abstract: Paeoniais the single genus of ca. 33 known species in the familyPaeoniaceae, found in Asia, Europe and Western North America. Up to now, more than 180 compounds have been isolated from nine species of the genusPaeonia, including terpenes, phenols, flavonoids, essential oil and tannins. Terpenes, the most abundant naturally occurring compounds, which accounted for about 57% and occurred in almost every species, are responsible for the observed in vivo and in vitro biological activities. This paper aims to give a comprehensive overview of the recent phytochemical and pharmacological knowledge of the terpenes fromPaeoniaplants, and enlighten further drug discovery research.
authors.affiliation: Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education, School of Chemistry and Materials Science, Heilongjiang University, 74 Xue-Fu Road, Nan-Gang District, Harbin 150080, China. zhaodandan@hlju.edu.cn.|Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Sciences, Heilongjiang University, Harbin 150080, China. zhaodandan@hlju.edu.cn.|Heilongjiang University Hospital, Harbin 150080, China. zhaodandan@hlju.edu.cn.
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Zhao
authors.affiliation: Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Sciences, Heilongjiang University, Harbin 150080, China. lljianghd@163.com.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Jiang
authors.affiliation: Heilongjiang University Hospital, Harbin 150080, China. hylihd@163.com.
authors.forename: Hong-Yi
authors.initials: HY
authors.lastname: Li
authors.affiliation: Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education, School of Chemistry and Materials Science, Heilongjiang University, 74 Xue-Fu Road, Nan-Gang District, Harbin 150080, China. yanpf@vip.sina.com.
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Yan
authors.affiliation: Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Sciences, Heilongjiang University, Harbin 150080, China. ylzhanghd@163.com.
authors.forename: Yan-Long
authors.initials: YL
authors.lastname: Zhang
mesh_terms: D000777:Anesthetics / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000494:pharmacology; D000925:Anticoagulants / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D055808:Drug Discovery; D006801:Humans; D006993:Hypnotics and Sedatives / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D029596:Paeonia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000777:Anesthetics; D000893:Anti-Inflammatory Agents; D000925:Anticoagulants; D000970:Antineoplastic Agents; D000975:Antioxidants; D006993:Hypnotics and Sedatives; D010936:Plant Extracts; D013729:Terpenes
keywords: Genus Paeonia; chemical components; pharmacological activities; terpene