title: Effect of culture conditions on metabolites produced by the crinoid-derived fungus Aspergillus ruber 1017.
abstract: Two different culture media were used to cultivate fungus Aspergillus ruber 1017 and resulted in the isolation of one new compound (1) and 23 known compounds (2-24). Alkaloids were the major metabolite in soybean medium instead of anthraquinone from rice medium. The structures of these compounds were elucidated according to spectroscopic analysis and comparison with reported data. Antibacterial activities of compounds 1-12 against 12 aquatic bacteria were evaluated.
authors.affiliation: a School of Marine Sciences , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Yong-Fang
authors.initials: YF
authors.lastname: Li
authors.affiliation: b School of Chemistry and Chemical Engineering , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Xue-Bin
authors.initials: XB
authors.lastname: Wu
authors.affiliation: a School of Marine Sciences , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Shah-Iram
authors.initials: SI
authors.lastname: Niaz
authors.affiliation: a School of Marine Sciences , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Liu-Hong
authors.initials: LH
authors.lastname: Zhang
authors.affiliation: a School of Marine Sciences , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Zhi-Jian
authors.initials: ZJ
authors.lastname: Huang
authors.affiliation: b School of Chemistry and Chemical Engineering , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Yong-Cheng
authors.initials: YC
authors.lastname: Lin
authors.affiliation: a School of Marine Sciences , Sun Yat-Sen University , Guangzhou , P.R. China.|c South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: a School of Marine Sciences , Sun Yat-Sen University , Guangzhou , P.R. China.|d Key Laboratory of Functional Molecules from Oceanic Microorganisms, Department of Education of Guangdong Province , Sun Yat-Sen University , Guangzhou , P.R. China.
authors.forename: Lan
authors.initials: L
authors.lastname: Liu
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification / Q000378:metabolism; D000880:Anthraquinones / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001230:Aspergillus / Q000737:chemistry / Q000378:metabolism*; D001419:Bacteria / Q000187:drug effects; D003470:Culture Media / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012275:Oryza / Q000378:metabolism; D013025:Glycine max / Q000378:metabolism; D013057:Spectrum Analysis
chemical_list: D000470:Alkaloids; D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D003470:Culture Media
keywords: Aspergillus ruber; Crinoid; culture conditions