title: Investigation of Nerve Conduction Studies of Carpal Tunnel Syndrome Cases With Different Risk Factors: An Electrodiagnostic Study.
abstract: OBJECTIVE
  The aim of this study was to determine whether there are electrodiagnostic differences between carpal tunnel syndrome (CTS) patients with diabetes mellitus, CTS + hypothyroidism (HT), CTS + fibromyalgia syndrome, CTS + rheumatoid arthritis (RA), and idiopathic CTS cases, by comparing nerve conduction studies.
  
  
  METHODS
  This research examined electrophysiologic studies of 47 untreated HT + CTS, 47 diabetes mellitus + CTS, 49 RA + CTS, 52 fibromyalgia syndrome + CTS, 50 idiopathic CTS cases, and a healthy control group of 50 individuals (a total of 293 patients and 433 hands with CTS).
  
  
  RESULTS
  There were no significant differences between the groups in terms of sex and age. There was no significant difference between the CTS groups-in terms of numbers-with mild, moderate, and severe CTS. When the CTS groups were compared with the control group, in all CTS groups on both left and right hands, there was a significant prolongation in median motor latency and median sensory latency (in the 3rd finger); also a significant decrease in median sensory velocity in the 3rd finger. In diabetes mellitus, HT, and RA groups, the median motor amplitudes in both hands were significantly decreased compared with the idiopathic group. There was a moderate significant negative correlation between disease duration and median motor amplitudes (of both right and left sides) in RA (right; P = 0.028, r = 0.761, left; P = 0.041, r = 0.694) and HT groups (right; P = 0.035, r = 0.637, left; P = 0.049, r = 0.697).
  
  
  CONCLUSIONS
  Electrodiagnostic results showed both demyelinating injury and axonal damage in diabetes mellitus, HT, and RA patients with CTS, in these patients during treatment for CTS. Early treatment planning should include the risk factor diseases.
authors.affiliation: *Department of Neurology, Faculty of Medicine, Trakya University, Edirne, Turkey; †Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Trakya University, Edirne, Turkey; ‡Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Gaziosmanpaşa University, Tokat, Turkey; and §Department of Neurology, Faculty of Medicine, Gaziosmanpaşa University, Tokat, Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Solmaz
authors.forename: Selçuk
authors.initials: S
authors.lastname: Yavuz
authors.forename: Ahmet
authors.initials: A
authors.lastname: İnanr
authors.forename: Dürdane
authors.initials: D
authors.lastname: Aksoy
authors.forename: Elmas
authors.initials: E
authors.lastname: Pektaş
authors.forename: Aslan
authors.initials: A
authors.lastname: Tekataş
authors.forename: Semiha G
authors.initials: SG
authors.lastname: Kurt
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications / Q000503:physiopathology; D002349:Carpal Tunnel Syndrome / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000503:physiopathology; D004568:Electrodiagnosis / Q000379:methods; D005260:Female; D005356:Fibromyalgia / Q000150:complications / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000503:physiopathology; D008297:Male; D008475:Median Nerve / Q000503:physiopathology*; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology*; D012307:Risk Factors; D012720:Severity of Illness Index; D014459:Ulnar Nerve / Q000503:physiopathology*