title: Outdated risk assessment in a family with Duchenne dystrophy: Implications for duty to reassess.
abstract: Carrier risk assessment for Duchenne muscular dystrophy (DMD) is necessary to counsel women at risks of developing cardiomyopathy and having a child with DMD. Comprehensive molecular testing for dystrophin gene mutations has only been available since 20031; women counseled earlier have outdated risk assessments. We present a 5-generation family in whom results of familial mutation testing for DMD newly identified 10 obligate carriers and 28 women at risk to be carriers for DMD.
authors.affiliation: Parent Project Muscular Dystrophy (L.B.), Hackensack, NJ; and Department of Neurology (L.B., S.R.), University of Michigan, Ann Arbor.
authors.forename: Lauren
authors.initials: L
authors.lastname: Bogue
authors.affiliation: Parent Project Muscular Dystrophy (L.B.), Hackensack, NJ; and Department of Neurology (L.B., S.R.), University of Michigan, Ann Arbor.
authors.forename: Sindhu
authors.initials: S
authors.lastname: Ramchandren