title: Imaging of Paget's disease of bone.
abstract: Paget's disease of bone is a disorder of bone remodelling, leading to changes in the architecture and overall appearance of the bone. The disorder may be monostotic or polyostotic and affect any bone in the body, although most commonly it involves the spine, pelvis, skull and femur. This article explores the different imaging modalities used in the assessment of Paget's disease of bone in its different phases. The relative merits of each imaging modality is discussed with illustrative examples, in particular with respect to radiographs, nuclear medicine bone scan, computed tomography (CT) and magnetic resonance imaging (MRI).
authors.affiliation: The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, SY10 7AG, Oswestry, Gobowen, UK. naomi.winn@rjah.nhs.uk.
authors.forename: Naomi
authors.initials: N
authors.lastname: Winn
authors.affiliation: The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, SY10 7AG, Oswestry, Gobowen, UK.
authors.forename: Radhesh
authors.initials: R
authors.lastname: Lalam
authors.affiliation: The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, SY10 7AG, Oswestry, Gobowen, UK.
authors.forename: Victor
authors.initials: V
authors.lastname: Cassar-Pullicino
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D010001:Osteitis Deformans / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
keywords: CT; MRI; Nuclear medicine bone scan; Paget’s disease; Radiographs