title: Occlusal rehabilitation in patients with congenitally missing teeth-dental implants, conventional prosthetics, tooth autotransplants, and preservation of deciduous teeth-a systematic review.
abstract: BACKGROUND
  Implant patients with congenitally missing teeth share some common charateristics and deserve special attention.
  
  
  METHODS
  The PICO question was "In patients with congenitally missing teeth, does an early occlusal rehabilitation with dental implants in comparison to tooth autotransplants, conventional prosthetics on teeth or preservation of deciduous teeth have better general outcomes in terms of survival, success and better patient centered outcomes in terms of quality of life, self-esteem, satisfaction, chewing function?" After electronic database search, a total of 63 relevant studies were eligible, of which 42 qualified for numerical data synthesis, 26 being retrospective studies. A data synthesis was performed by weighted means for survival/success/annual failure rates.
  
  
  RESULTS
  The mean survival of implants was 95.3 % (prosthesis survival 97.8 %), autotransplants 94.4 %, deciduous teeth 89.6 %, and conventional prostheses 60.2 %. The implant survival in children, adolescents, and adults was 72.4, 93.0, and 97.4 %. Annual failure rates of implants 3.317 %, autotransplants 1.061 %, deciduous teeth 0.908 %, and conventional prostheses 5.144 % indicated better results for natural teeth and more maintenance needs for the both prosthetic treatments. The mean OHIP score was 27.8 at baseline and a mean improvement of 14.9 score points was reported after implant prosthetics. The mean satisfaction rates were 93.4 (implants), 76.6 (conventional prostheses), 72.0 (autotransplants), and 65.5 % (orthodontic space closure).
  
  
  CONCLUSIONS
  In synopsis of general and patient-centered outcomes, implants yielded the best results, however, not in children <13 years. Autotransplants and deciduous teeth had low annual failure rates and are appropriate treatments in children and adolescents at low costs. Conventional prosthetics had lower survival/success rates than the other options. Due to heterogeneity and low number of studies, patient-reported outcomes in this review have to be interpreted with caution.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Red Cross Hospital, Hansteinstr. 29, D-34121, Kassel, Germany. Terheyden@rkh-kassel.de.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Terheyden
authors.affiliation: Department of Oral and Maxillofacial Surgery, Schleswig-Holstein University Hospital, Arnold-Heller-Straße 3, Haus 26, 2D-4105, Kiel, Germany.
authors.forename: Falk
authors.initials: F
authors.lastname: Wüsthoff
keywords: Anodontia; Congenitally missing teeth; Deciduous tooth; Dental implants; Ectodermal dysplasia; Hypodontia; Oligodontia; Tooth agenesis; Tooth aplasia; Tooth autotransplantation