title: Failure of Risk-Adjustment by Test Method for C. difficile Laboratory-Identified Event Reporting.
abstract: Using an algorithm including both enzyme immunoassay (EIA) and nucleic acid amplification (NAAT) for Clostridium difficile infection (CDI) diagnosis, we found that the use of NAAT versus EIA almost doubled our hospital-onset CDI laboratory-identified (LabID) event standardized infection ratio (SIR). We recommend that the current risk adjustment approach be modified. Infect Control Hosp Epidemiol 2016:1-3.
authors.affiliation: 1Office of Clinical Quality,Safety,and Performance Improvement,University of Iowa Hospitals and Clinics,Iowa City,Iowa.
authors.forename: Alexandre R
authors.initials: AR
authors.lastname: Marra
authors.affiliation: 1Office of Clinical Quality,Safety,and Performance Improvement,University of Iowa Hospitals and Clinics,Iowa City,Iowa.
authors.forename: Michael B
authors.initials: MB
authors.lastname: Edmond
authors.affiliation: 3Division of Medical Microbiology,Department of Pathology,University of Iowa,Carver College of Medicine.
authors.forename: Bradley A
authors.initials: BA
authors.lastname: Ford
authors.affiliation: 2Division of Infectious Diseases,Department of Internal Medicine,University of Iowa,Carver College of Medicine,Iowa City,Iowa.
authors.forename: Loreen A
authors.initials: LA
authors.lastname: Herwaldt
authors.affiliation: 1Office of Clinical Quality,Safety,and Performance Improvement,University of Iowa Hospitals and Clinics,Iowa City,Iowa.
authors.forename: Abdullah R
authors.initials: AR
authors.lastname: Algwizani
authors.affiliation: 1Office of Clinical Quality,Safety,and Performance Improvement,University of Iowa Hospitals and Clinics,Iowa City,Iowa.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Diekema
mesh_terms: D000465:Algorithms; D016360:Clostridioides difficile; D003015:Clostridium Infections / Q000175:diagnosis*; D003428:Cross Infection / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques; D021141:Nucleic Acid Amplification Techniques; D020379:Risk Adjustment; D062606:Tertiary Care Centers