title: Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy.
abstract: Malignant salivary gland tumors are rare in children, mostly represented by low-grade mucoepidermoid carcinomas. For these patients, long-term survival rates above 95% are reported after surgical resection. Here we report a case of a 9-year-old girl with a high grade locally advanced mucoepidermoid carcinoma undergoing adjuvant radiotherapy and chemotherapy after surgery. We emphasize the controversy and lack of evidence-based indication for these highly toxic adjuvant therapy modalities in children.
authors.affiliation: Department of Oncology and Pediatric Hematology, University Hospital Virgen de la Arrixaca , Murcia, Spain.
authors.forename: Olga Micol
authors.initials: OM
authors.lastname: Martínez
authors.affiliation: Department of Oncology and Pediatric Hematology, University Hospital Virgen de la Arrixaca , Murcia, Spain.
authors.forename: Elena Daghoum
authors.initials: ED
authors.lastname: Dorado
authors.affiliation: Department of Maxillofacial Surgery, University Hospital Virgen de la Arrixaca , Murcia, Spain.
authors.forename: María Dolores Amorós
authors.initials: MD
authors.lastname: García
authors.affiliation: Department of Pathology, University Hospital Virgen de la Arrixaca , Murcia, Spain.
authors.forename: María Isabel Oviedo
authors.initials: MI
authors.lastname: Ramírez
authors.affiliation: Department of Radiotherapy Oncology, University Hospital Virgen de la Arrixaca , Murcia, Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: de la Fuente Muñoz
authors.affiliation: Department of Oncology and Pediatric Hematology, University Hospital Virgen de la Arrixaca , Murcia, Spain.
authors.forename: Jose Luis Fuster
authors.initials: JL
authors.lastname: Soler
keywords: High-grade; carcinoma; children; mucoepidermoyd