title: Evaluation of Syringomas by In Vivo Reflectance Confocal Microscopy: A Report of Two Cases.
abstract: Syringomas are benign adnexal tumors that are characterized histologically by the presence of small solid and cystic epithelial structures in the upper half of the reticular dermis. Reflectance confocal microscopy is a noninvasive diagnostic method that enables in vivo visualization of tissues with a resolution that approximates that of conventional histopathology. The use of this method in skin imaging over the past several years has improved dermatological diagnoses, creating the potential for its wide application in such diagnoses, especially for benign and malignant skin tumors. We describe its use in the diagnosis of syringoma in 2 patients and correlate the resulting clinical, histopathological, and digital reflectance confocal microscopy images.
authors.affiliation: *Department of Dermatology, University of São Paulo, São Paulo, Brazil; †Department of Pathology, Hospital Obrero, La Paz, Bolivia; and ‡Department of Pathology, Dental School, University of São Paulo, São Paulo, Brazil.
authors.forename: Marcela R
authors.initials: MR
authors.lastname: Jiménez
authors.forename: Helena
authors.initials: H
authors.lastname: Rocchetto
authors.forename: Paula S
authors.initials: PS
authors.lastname: Ferreira
authors.forename: Martin
authors.initials: M
authors.lastname: Sangueza
authors.forename: Silvia V
authors.initials: SV
authors.lastname: Lourenço
authors.forename: Marcello M S
authors.initials: MMS
authors.lastname: Nico
mesh_terms: D001706:Biopsy; D005260:Female; D006801:Humans; D018613:Microscopy, Confocal / Q000379:methods*; D011237:Predictive Value of Tests; D013544:Sweat Gland Neoplasms / Q000473:pathology*; D018252:Syringoma / Q000473:pathology*