title: Feasibility of viral dust infection via air movement and dispersion of dried viral particles from the floor.
abstract: The contributions of splash from vomiting and the dispersion of dried-up virus from a contaminated floor surface to community gastroenteritis outbreaks caused by Norovirus (NoV) were evaluated, using Feline calicivirus (FCV) as an NoV surrogate. There was no difference in the size distribution of FCV-containing particles around 0.75 µm) collected from a virus-sprayed chamber 1 and 12 hr after nebulization. FCV clearly dispersed after hitting a floor surface contaminated with dried virus. These results suggest that NoV can likely form airborne droplet nuclei, and dust may be the main route of infection transmission. J. Med. Virol. 89:931-935, 2017. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Tokyo Metropolitan Institute of Public Health, Shinjuku, Tokyo, Japan.
authors.forename: Kohji
authors.initials: K
authors.lastname: Mori
authors.affiliation: Tokyo Metropolitan Institute of Public Health, Shinjuku, Tokyo, Japan.
authors.forename: Aya
authors.initials: A
authors.lastname: Onuki
authors.affiliation: Tokyo Metropolitan Institute of Public Health, Shinjuku, Tokyo, Japan.
authors.forename: Fumio
authors.initials: F
authors.lastname: Kanou
authors.affiliation: Tokyo Metropolitan Institute of Public Health, Shinjuku, Tokyo, Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Akiba
authors.affiliation: Tokyo Metropolitan Institute of Public Health, Shinjuku, Tokyo, Japan.
authors.forename: Yukinao
authors.initials: Y
authors.lastname: Hayashi
authors.affiliation: Graduate School of Medicine, Chiba University, Chiba, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shirasawa
authors.affiliation: Tokyo Metropolitan Institute of Public Health, Shinjuku, Tokyo, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Sadamasu
mesh_terms: D000392:Air Movements; D000818:Animals; D017250:Caliciviridae Infections / Q000635:transmission; D017927:Calicivirus, Feline / Q000302:isolation & purification*; D003890:Desiccation; D018562:Disease Transmission, Infectious; D004391:Dust; D004783:Environmental Microbiology; D005430:Floors and Floorcoverings; D006801:Humans; D008962:Models, Theoretical; D014771:Virion / Q000302:isolation & purification*
chemical_list: D004391:Dust
keywords: generalized infection; horizontal transmission; viral excretion