title: Embryonal Rhabdomyosarcoma of the Oral Cavity.
abstract: A 19 year old female presents to the emergency room with right facial enlargement. Clinical examination revealed a soft tissue mass of the right buccal mucosa. Treated initially as infection, the patient later turned to clinic with now rapidly enlarging and intermittently painful mass. Computed tomography with contrast showed a low attenuated buccal mass with mild enhancement lateral to the right caudal maxilla and superior mandible. Biopsy was performed and microscopic examination showed cells with moderate pleomorphism with numerous atypical mitotic figures and occasional elongated "strap" cells with eccentric nuclei. Fluorescence in situ hybridization analysis revealed no rearrangement of the FKHR gene. The diagnosis of embryonal rhabdomyosarcoma was rendered. The patient was referred to the local children's hospital for definitive treatment.
authors.affiliation: Department of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA. mark.o.mcinturff.mil@mail.mil.
authors.forename: Mark
authors.identifier: http://orcid.org/0000-0003-3845-2224
authors.initials: M
authors.lastname: McInturff
authors.affiliation: Department of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA.
authors.forename: Anne
authors.initials: A
authors.lastname: Adamson
authors.affiliation: Department of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA.
authors.forename: Chadwick
authors.initials: C
authors.lastname: Donaldson
authors.affiliation: Department of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA.
authors.forename: Brenda L
authors.initials: BL
authors.lastname: Nelson
mesh_terms: D005260:Female; D006801:Humans; D009062:Mouth Neoplasms / Q000473:pathology*; D018233:Rhabdomyosarcoma, Embryonal / Q000473:pathology*; D055815:Young Adult
keywords: Buccal mucosa; Desmin; Embryonal rhabdomyosarcoma; Histology; MyoD1; Myogenin; Oral cavity