title: Pilot randomized controlled trial to assess a physical therapy program on upper extremity function to counteract inactivity in chronic stroke.
abstract: In chronic stroke, feasible physical therapy (PT) programs are needed to promote function throughout life.
  
  
  
  This randomized controlled pilot trial investigated the feasibility and effect of a PT program composed of strengthening exercises with elastic bands and bimanual functional training, with clearly defined doses based on the rate of perceived exertion (Borg scale), to counteract inactivity in chronic stroke.
  
  
  
  Fifteen subjects > 6 month post-stroke were randomized to three-month of UE function training (UE group), or to lower extremity function training (LE group). At baseline (T0), post-intervention (T1) and three-month follow-up (T2) assessment included the Fugl-Meyer Assessment scale (FMA), Wolf Motor Function test (WMFT), grip strength, and muscle tone. Feasibility was also evaluated.
  
  
  
  The mixed-model ANOVAs revealed a significant interaction between the time and group factors for FMA (p < .001) and WMFT (p = .009). The UE group improved upper extremity function and motor recovery significantly more than the LE group. There was no significant interaction between treatment group and change in grip strength over time (p = .217). No between-group differences (p > .05) were found in muscle tone. In the UE group, the attendance rate was ≥85% for 71.4% of subjects and 85.7% showed high satisfaction. No adverse events were recorded. After treatment, adherence to the program was higher in the UE group.
  
  
  
  The suggested PT program may be useful to improve the paretic UE function and motor recovery in chronic stroke. Moreover, it may be helpful to facilitate lifelong active involvement of stroke subjects in exercise.
authors.affiliation: a Faculty of Physical Therapy, Department of Physical Therapy , University of Valencia , Valencia , Spain.
authors.forename: M Luz
authors.initials: ML
authors.lastname: Sánchez-Sánchez
authors.affiliation: a Faculty of Physical Therapy, Department of Physical Therapy , University of Valencia , Valencia , Spain.
authors.forename: Maria-Arántzazu
authors.initials: MA
authors.lastname: Ruescas-Nicolau
authors.affiliation: a Faculty of Physical Therapy, Department of Physical Therapy , University of Valencia , Valencia , Spain.|b Nueva Opción - Brain Damage Association , Valencia , Spain.
authors.forename: José-Antonio
authors.initials: JA
authors.lastname: Pérez-Miralles
authors.affiliation: a Faculty of Physical Therapy, Department of Physical Therapy , University of Valencia , Valencia , Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Marqués-Sulé
authors.affiliation: a Faculty of Physical Therapy, Department of Physical Therapy , University of Valencia , Valencia , Spain.
authors.forename: Gemma-Victoria
authors.initials: GV
authors.lastname: Espí-López
mesh_terms: D000368:Aged; D002908:Chronic Disease / Q000534:rehabilitation; D005081:Exercise Therapy / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010865:Pilot Projects; D016037:Single-Blind Method; D020521:Stroke / Q000628:therapy*; D000071939:Stroke Rehabilitation / Q000379:methods*; D034941:Upper Extremity / Q000503:physiopathology*
keywords: Function; Neurologic physical therapy; Physical inactivity; Resistance training; Stroke; Upper extremity