title: Gastric Metastasis of Breast Cancer: A Case Series.
abstract: Gastric metastasis is rare but it can be the initial symptom of cancer. The second leading cause of this type of metastasis is breast cancer. A lack of clinical signs and nonspecific side effects of the treatment of primary tumors can lead to the misdiagnosis of metastatic gastric cancer. Upper gastrointestinal endoscopy with biopsy and immunohistochemistry should be used for diagnosis. Treatment is palliative; it includes chemo, endocrine, and radiation therapies. Four patients with breast cancer and gastric metastasis were identified. All the patients tested positive for estrogen and progesterone receptors, and received chemotherapy and hormone therapy. One patient underwent surgery and two received radiation therapy. Patients with breast cancer and gastrointestinal symptoms should be investigated for gastric metastasis, given its morbidity and negative impact on quality of life.
authors.affiliation: Department of Oncology, Hospital Sírio Libanês, Unidade Brasília , Brasil.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Dos Santos Fernandes
authors.affiliation: Department of Oncology, Hospital Sírio Libanês, Unidade Brasília , Brasil.
authors.forename: Luiza D
authors.initials: LD
authors.lastname: Batista Bugiato Faria
authors.affiliation: School of Medicine, Catholic University of Brasília , Brasil.
authors.forename: Isadora
authors.initials: I
authors.lastname: de Assis Pereira
authors.affiliation: School of Medicine, Catholic University of Brasília , Brasil.
authors.forename: Natália C Moreira
authors.initials: NC
authors.lastname: Neves
authors.affiliation: School of Medicine, Catholic University of Brasília , Brasil.
authors.forename: Yasmine Oliveira
authors.initials: YO
authors.lastname: Vieira
authors.affiliation: Department of Oncology, Hospital Sírio Libanês, Unidade Brasília , Brasil.
authors.forename: Alessandro I Cavalcanti
authors.initials: AI
authors.lastname: Leal
keywords: Breast cancer; chemotherapy; gastric metastasis; hormonal therapy; immunohistochemistry