title: Selective detection of dopamine with an all PEDOT:PSS Organic Electrochemical Transistor.
abstract: An all PEDOT:PSS Organic Electrochemical Transistor (OECT) has been developed and used for the selective detection of dopamine (DA) in the presence of interfering compounds (ascorbic acid, AA and uric acid, UA). The selective response has been implemented using a potentiodynamic approach, by varying the operating gate voltage and the scan rate. The trans-conductance curves allow to obtain a linear calibration plot for AA, UA and DA and to separate the redox waves associated to each compound; for this purpose, the scan rate is an important parameter to achieve a good resolution. The sensitivities and limits of detection obtained with the OECT have been compared with those obtained by potential step amperometric techniques (cyclic voltammetry and differential pulse voltammetry), employing a PEDOT:PSS working electrode: our results prove that the all-PEDOT:PSS OECT sensitivities and limits of detection are comparable or even better than those obtained by DPV, a technique that employs a sophisticate potential wave and read-out system in order to maximize the performance of electrochemical sensors and that can hardly be considered a viable readout method in practical applications.
authors.affiliation: Dipartimento di Chimica Industriale 'Toso Montanari', Università di Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
authors.forename: Isacco
authors.initials: I
authors.lastname: Gualandi
authors.affiliation: Dipartimento di Chimica Industriale 'Toso Montanari', Università di Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
authors.forename: Domenica
authors.initials: D
authors.lastname: Tonelli
authors.affiliation: Dipartimento di Chimica Industriale 'Toso Montanari', Università di Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Mariani
authors.affiliation: Dipartimento di Chimica Industriale 'Toso Montanari', Università di Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
authors.forename: Erika
authors.initials: E
authors.lastname: Scavetta
authors.affiliation: Dipartimento di Fisica e Astronomia, Università di Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Marzocchi
authors.affiliation: Dipartimento di Fisica e Astronomia, Università di Bologna, Viale Berti Pichat 6/2, 40127 Bologna, Italy.
authors.forename: Beatrice
authors.initials: B
authors.lastname: Fraboni
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D001205:Ascorbic Acid / Q000737:chemistry; D004298:Dopamine / Q000032:analysis*; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods*; D010084:Oxidation-Reduction; D011137:Polystyrenes / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013876:Thiophenes / Q000737:chemistry*; D014173:Transistors, Electronic; D014527:Uric Acid
chemical_list: D000596:Amino Acids; D011137:Polystyrenes; D013876:Thiophenes; C533756:poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate); D014527:Uric Acid; D001205:Ascorbic Acid; D004298:Dopamine