title: Ziprasidone Augmentation in an Adolescent with Obsessive Compulsive Disorder: A Case Report.
abstract: Obsessive compulsive disorder (OCD) is characterized by recurrent, unwanted thoughts (obsessions) and/or repetitive behaviors (compulsions). Although selective serotonin reuptake inhibitors are widely used to treat OCD, only half of the patients respond well. Several potentiation strategies including off-label use of antipsychotics (mostly risperidone, quetiapine) have been tried. Ziprasidone is an atypical antipsychotic with the best affinity ratio of 5 HT2A/D2and 5HT2C/D2receptors. There is a limited data on ziprasidone in pediatric groups. The case described in the following is an example for the augmentation with ziprasidone to treatment refractory OCD.
authors.affiliation: Dr. Demirkaya, MD, Assistant Professor, Child and Adolescent Psychiatry, Adnan Menderes University Faculty of Medicine, Aydin, Turkey. Dr. Alyanak, MD, Professor, Child and Adolescent Psychiatry, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey.
authors.forename: Sevcan Karakoç
authors.initials: SK
authors.lastname: Demirkaya
authors.affiliation: Dr. Demirkaya, MD, Assistant Professor, Child and Adolescent Psychiatry, Adnan Menderes University Faculty of Medicine, Aydin, Turkey. Dr. Alyanak, MD, Professor, Child and Adolescent Psychiatry, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey.
authors.forename: Behiye
authors.initials: B
authors.lastname: Alyanak
keywords: augmentation; obsessive compulsive disorder; ziprasidone