title: Bacteremic vs nonbacteremic urinary tract infection in children.
abstract: OBJECTIVE
  Bacteremia is an uncommon complication of urinary tract infection (UTI). The aim of this study was to identify risk factors for bacteremic UTI in pediatric patients.
  
  
  METHODS
  The medical records of all pediatric patients with UTI between 2013 and 2014 were retrospectively reviewed. Pediatric patients with accompanying bacteremia were compared with pediatric patients with no bacteremia.
  
  
  RESULTS
  Five hundred twenty-seven cases of UTI were identified. Blood cultures were taken in 464, 26 (5.6%) of which also were bacteremic. Pediatric patients with bacteremia were more likely to be male (58% vs 28%, P<.01), to be younger than 3 months (54% vs 31%, P=.02), and to have higher creatinine (average 0.77±0.97 vs 0.34±0.24, P<.01). Pediatric patients with bacteremia had higher rate of underlying urologic conditions. The following variables were included in multivariate analysis: age <3months, sex, ethnicity, method of urine collection, creatinine, and underlying urologic conditions. Only creatinine (odds ratio, 3.67; 95% confidence interval, 1.69-8.11) was found as an independent risk factor for bacteremia.
  
  
  CONCLUSIONS
  High creatinine at presentation is a risk factor that might aid in early identification of pediatric patients with high risk for bacteremia and its complications.
authors.affiliation: Pediatric Department and Infectious Diseases Unit, Shaare Zedek Medical Center affiliated with Hebrew University-Hadassah School of Medicine, Jerusalem, Israel. Electronic address: orlimegged@yahoo.com.
authors.forename: Orli
authors.initials: O
authors.lastname: Megged
mesh_terms: D000367:Age Factors; D018912:Arabs / Q000706:statistics & numerical data; D016470:Bacteremia / Q000453:epidemiology*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood*; D004927:Escherichia coli Infections / Q000097:blood / Q000453:epidemiology*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric / Q000706:statistics & numerical data; D007557:Israel / Q000453:epidemiology; D007585:Jews / Q000706:statistics & numerical data; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D014552:Urinary Tract Infections / Q000097:blood / Q000453:epidemiology*; D059349:Urine Specimen Collection / Q000379:methods*; D014570:Urologic Diseases / Q000453:epidemiology*
chemical_list: D003404:Creatinine