title: Update on Image-Guided Percutaneous Ablation of Breast Cancer.
abstract: OBJECTIVE
  The purpose of this article is to delineate the potential techniques for percutaneous ablation of breast cancer, discuss the advantages and disadvantages of each technique, and provide results from recent studies on these technologies. The techniques discussed are cryotherapy, laser irradiation, microwave irradiation, radiofrequency ablation, high-intensity focused ultrasound ablation, and irreversible electroporation.
  
  
  CONCLUSIONS
  Although percutaneous ablation techniques have some promising potential for less-invasive treatment of breast cancer, larger multicenter trials are needed to confirm their efficacy, especially in comparison with the reference standard of lumpectomy. The use of these techniques also leads to other remaining unanswered questions, including how to manage the axilla and which patients are the best candidates for these treatments.
authors.affiliation: 1 Department of Radiology and Imaging Sciences, Winship Cancer Institute, Emory University, 1701 Uppergate Dr, Ste C-1104, Atlanta, GA 30322.
authors.forename: Margaret M
authors.initials: MM
authors.lastname: Fleming
authors.affiliation: 1 Department of Radiology and Imaging Sciences, Winship Cancer Institute, Emory University, 1701 Uppergate Dr, Ste C-1104, Atlanta, GA 30322.
authors.forename: Anna I
authors.initials: AI
authors.lastname: Holbrook
authors.affiliation: 1 Department of Radiology and Imaging Sciences, Winship Cancer Institute, Emory University, 1701 Uppergate Dr, Ste C-1104, Atlanta, GA 30322.
authors.forename: Mary S
authors.initials: MS
authors.lastname: Newell
mesh_terms: D055011:Ablation Techniques / Q000379:methods*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D018274:Electroporation / Q000379:methods*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D016896:Treatment Outcome
keywords: breast cancer; cryoablation; high-intensity focused ultrasound; percutaneous ablation; radiofrequency ablation