title: Rapid onset of hemophagocytic lymphohistiocytosis in a patient with refractory chronic lymphocytic leukemia treated with ibrutinib.
authors.affiliation: a Division of Hematology and Hematologic Malignancies , Huntsman Cancer Hospital, University of Utah , Salt Lake City , UT , USA.
authors.forename: Austin
authors.initials: A
authors.lastname: Poole
authors.affiliation: b Department of Pathology ARUP Laboratories , University of Utah , Salt Lake City , UT , USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Girard
authors.affiliation: b Department of Pathology ARUP Laboratories , University of Utah , Salt Lake City , UT , USA.
authors.forename: Frederic
authors.initials: F
authors.lastname: Clayton
authors.affiliation: a Division of Hematology and Hematologic Malignancies , Huntsman Cancer Hospital, University of Utah , Salt Lake City , UT , USA.
authors.forename: Srinivas K
authors.initials: SK
authors.lastname: Tantravahi
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D001344:Autopsy; D001706:Biopsy; D002869:Chromosome Aberrations; D019008:Drug Resistance, Neoplasm; D017809:Fatal Outcome; D015322:Gene Rearrangement, B-Lymphocyte; D006801:Humans; D016130:Immunophenotyping; D017404:In Situ Hybridization, Fluorescence; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010880:Piperidines; D047428:Protein Kinase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D011720:Pyrazoles / Q000009:adverse effects* / Q000627:therapeutic use; D011743:Pyrimidines / Q000009:adverse effects* / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D010880:Piperidines; D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D011743:Pyrimidines; C551803:ibrutinib; D000225:Adenine