title: Influence of Obesity on Liver Transplantation Outcomes.
abstract: OBJECTIVE
  The aim of this work was to determine the impact of obesity on the morbidity and mortality of liver transplantation (LT) recipients.
  
  
  METHODS
  A single-center, observational-cohort, retrospective study was conducted in patients undergoing LT from January 2008 to December 2014 to compare complications and survival between those with body mass index (BMI) <35 kg/m2and those with BMI ≥35 kg/m2.
  
  
  RESULTS
  The study included 170 patients: 162 (95.3%) with BMI <35 kg/m2and 8 (4.7%) with BMI ≥35 kg/m2. The groups significantly differed in overall mortality and graft survival: The risk of death was 3.54-fold higher (95% confidence interval, 1.39-9.03) and the mean graft survival was shorter (61 vs 21 mo; P = .001) in the group with BMI ≥35 kg/m2. The groups did not significantly differ in rates of biliary complications, arterial and portal vein thrombosis, retransplantation or reintervention, intraoperative requirement for blood products, length of intensive care unit stay, or post-reperfusion syndrome or rejection rates.
  
  
  CONCLUSIONS
  Although no significant differences were found between these groups in post-transplantation complications, BMI ≥35 kg/m2emerged as a mortality risk factor in these patients.
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain. Electronic address: by_andrea_1989@hotmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Molina Raya
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: A
authors.initials: A
authors.lastname: García Navarro
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: C
authors.initials: C
authors.lastname: San Miguel Méndez
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Domínguez Bastante
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: M T
authors.initials: MT
authors.lastname: Villegas Herrera
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: K
authors.initials: K
authors.lastname: Granero
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Becerra Massare
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Villar Del Moral
authors.affiliation: Research Support Unit, Fundación para la Investigación Biosanitaria de Andalucía Oriental, Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Expósito
authors.affiliation: Unit of HBP Surgery and Liver Transplant, Virgen de las Nieves University Complex, Granada, Spain.
authors.forename: Y
authors.initials: Y
authors.lastname: Fundora Suárez
mesh_terms: D000328:Adult; D015992:Body Mass Index; D015331:Cohort Studies; D005260:Female; D006085:Graft Survival; D006801:Humans; D016031:Liver Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome