title: Sjögren's syndrome associated with systemic lupus erythematosus.
abstract: Systemic lupus erythematosus and Sjögren's syndrome are chronic auto- inflammatory disorders which can lead to serious organ damage. Although systemic lupus erythematosus and Sjögren's syndrome were previously considered two forms of the same disease because of presence of clinical coexistence of these two conditions, the view that they are two different conditions with mutual characteristics has become prominent in recent years. In this paper, we reported a 16 year-old girl who was followed up with a diagnosis of Sjögren's syndrome for six years and then was observed to have overlap of systemic lupus erythematosus. In the baseline, she did not have any clinical or serological evidence for systemic lupus erythematosus. After six year, massive proteinuria and serological findings developed and systemic lupus erythematosus nephritis was diagnosed by kidney biopsy. Currently, systemic lupus erythematosus and Sjögren's syndrome cannot be differentiated definetely. We need more valuable diagnostic and classification criteria to differentiate these two important conditions.
authors.affiliation: Department of Pediatrics, Division of Pediatric Nephrology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Taşdemir
authors.affiliation: Department of Pediatrics, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
authors.forename: Chiar
authors.initials: C
authors.lastname: Hasan
authors.affiliation: Department of Pediatrics, Division of Pediatric Nephrology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
authors.forename: Ayşe
authors.initials: A
authors.lastname: Ağbaş
authors.affiliation: Department of Pediatrics, Division of Pediatric Rheumatology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
authors.forename: Özgür
authors.initials: Ö
authors.lastname: Kasapçopur
authors.affiliation: Department of Pediatrics, Division of Pediatric Nephrology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
authors.forename: Nur
authors.initials: N
authors.lastname: Canpolat
authors.affiliation: Department of Pediatrics, Division of Pediatric Nephrology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
authors.forename: Lale
authors.initials: L
authors.lastname: Sever
authors.affiliation: Department of Pediatrics, Division of Pediatric Nephrology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
authors.forename: Salim
authors.initials: S
authors.lastname: Çalışkan
keywords: Childhood; Sjögren’s syndrome; systemic lupus erythematosus