title: Diagnosis, Therapy and Follow-up Care of Vulvar Cancer and its Precursors. Guideline of the DGGG and DKG (S2k-Level, AWMF Registry Number 015/059, November 2015.
abstract: Purpose:This is an official guideline, published and coordinated by the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO, Study Group for Gynecologic Oncology) of the Deutsche Krebsgesellschaft (DKG, German Cancer Society) and the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe (DGGG, German Society for Gynecology and Obstetrics). The number of cases with vulvar cancer is on the rise, but because of the former rarity of this condition and the resulting lack of literature with a high level of evidence, in many areas knowledge of the optimal clinical management still lags behind what would be required. This updated guideline aims to disseminate the most recent recommendations, which are much clearer and more individualized, and is intended to create a basis for the assessment and improvement of quality care in hospitals.Methods:This S2k guideline was drafted by members of the AGO Committee on Vulvar and Vaginal Tumors; it was developed and formally completed in accordance with the structured consensus process of the Association of Scientific Medical Societies in Germany (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften, AWMF).Recommendations:1. The incidence of disease must be taken into consideration. 2. The diagnostic pathway, which is determined by the initial findings, must be followed. 3. The clinical and therapeutic management of vulvar cancer must be done on an individual basis and depends on the stage of disease. 4. The indications for sentinel lymph node biopsy must be evaluated very carefully. 5. Follow-up and treatment for recurrence must be adapted to the individual case.
authors.affiliation: ehem. Frauenklinik Lukaskrankenhaus, Neuss.
authors.forename: H G
authors.initials: HG
authors.lastname: Schnürch
authors.affiliation: Frauenklinik, Klinikum Darmstadt, Darmstadt.
authors.forename: S
authors.initials: S
authors.lastname: Ackermann
authors.affiliation: Institut für Diagnostische und Interventionelle Radiologie, Universität Düsseldorf, Düsseldorf.
authors.forename: C D
authors.initials: CD
authors.lastname: Alt
authors.affiliation: Klinik für Gynäkologie und Geburtshilfe, Markus Krankenhaus, Frankfurt am Main.
authors.forename: J
authors.initials: J
authors.lastname: Barinoff
authors.affiliation: Katholisches Klinikum Oberhausen, Frauenklinik St. Clemens-Hospital, Oberhausen.
authors.forename: C
authors.initials: C
authors.lastname: Böing
authors.affiliation: Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe der Universität München, Campus Großhadern, München, Munich.
authors.forename: C
authors.initials: C
authors.lastname: Dannecker
authors.affiliation: Dysplasiezentrum in der Frauenarztpraxis Heussweg, Hamburg.
authors.forename: F
authors.initials: F
authors.lastname: Gieseking
authors.affiliation: Frauenklinik Luzerner Kantonsspital, Lucerne, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Günthert
authors.affiliation: Abteilung Gynäkologie und Geburtshilfe, Kreiskliniken Altötting - Burghausen, Altötting.
authors.forename: P
authors.initials: P
authors.lastname: Hantschmann
authors.affiliation: Institut für Pathologie des Universitätsklinikums Leipzig, Leipzig.
authors.forename: L C
authors.initials: LC
authors.lastname: Horn
authors.affiliation: ehem. Universitätsfrauenklinik Maistraße, Munich.
authors.forename: R
authors.initials: R
authors.lastname: Kürzl
authors.affiliation: Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe der Universität Köln, Cologne.
authors.forename: P
authors.initials: P
authors.lastname: Mallmann
authors.affiliation: Klinik und Poliklinik für Radioonkologie und Strahlentherapie der Universität Köln, Cologne.
authors.forename: S
authors.initials: S
authors.lastname: Marnitz
authors.affiliation: Universitätsfrauenklinik Erlangen, Erlangen.
authors.forename: G
authors.initials: G
authors.lastname: Mehlhorn
authors.affiliation: Universitätsfrauenklinik Erlangen, Erlangen.
authors.forename: C C
authors.initials: CC
authors.lastname: Hack
authors.affiliation: Universitätsfrauenklinik Erlangen, Erlangen.
authors.forename: M C
authors.initials: MC
authors.lastname: Koch
authors.affiliation: Klinik für Gynäkologie und Zentrum für Beckenbodenerkrankungen, Vivantes Klinikum Neukölln, Berlin.
authors.forename: U
authors.initials: U
authors.lastname: Torsten
authors.affiliation: Klinik für Gynäkologie und gynäkologische Onkologie, Universitätsfrauenklinik Mainz, Mainz.
authors.forename: W
authors.initials: W
authors.lastname: Weikel
authors.affiliation: Klinik und Poliklinik für Gynäkologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg.
authors.forename: L
authors.initials: L
authors.lastname: Wölber
authors.affiliation: Klinik für Frauenheilkunde und Geburtshilfe des Universitätsklinikums Düsseldorf, Düsseldorf.
authors.forename: M
authors.initials: M
authors.lastname: Hampl
keywords: diagnosis; therapy; vulvar cancer; vulvar intraepithelial neoplasia