title: Cocaine-induced very late stent thrombosis.
abstract: Cocaine misuse is a known cause of acute coronary syndrome (ACS). Management of these patients has always been a challenge due to medication compliance and eventual risk of stent thrombosis. However, even cocaine misusers who are compliant with dual antiplatelet therapy have been reported to have stent thrombosis. All cases of cocaine-induced stent thrombosis reported in the literature have occurred within first year of stent placement (acute, subacute or late). We report a first case of very late stent thrombosis in a 54-year-old active cocaine misuser who presented with ST segment elevation myocardial infarction, which was successfully managed with percutaneous transluminal coronary angioplasty. A review of all the reported cases of cocaine-induced stent thrombosis is also discussed. Given the high mortality associated with stent thrombosis, treatment option for cocaine misusers presenting with ACS should be conservative when possible. If percutaneous coronary intervention is needed, bare metal stent should be preferred.
authors.affiliation: Department of Cardiology, New York Medical College at St Joseph's Regional Medical Center, Paterson, New Jersey, USA.
authors.forename: Priyank
authors.initials: P
authors.lastname: Shah
authors.affiliation: Department of Internal Medicine, New York Medical College at St Joseph's Regional Medical Center, Paterson, New Jersey, USA.
authors.forename: Rahul
authors.identifier: http://orcid.org/0000-0001-7323-5837
authors.initials: R
authors.lastname: Vasudev
authors.affiliation: Department of Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey, USA.
authors.forename: Ahmad Hisham
authors.initials: AH
authors.lastname: Abuarqoub
authors.affiliation: Department of Cardiology, New York Medical College at St Joseph's Regional Medical Center, Paterson, New Jersey, USA.
authors.forename: Fayez
authors.initials: F
authors.lastname: Shamoon
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D003042:Cocaine / Q000009:adverse effects*; D019970:Cocaine-Related Disorders / Q000150:complications; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000139:chemically induced / Q000000981:diagnostic imaging; D003328:Coronary Thrombosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D018765:Dopamine Uptake Inhibitors / Q000009:adverse effects*; D006083:Graft Occlusion, Vascular / Q000139:chemically induced* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D000072657:ST Elevation Myocardial Infarction / Q000000981:diagnostic imaging / Q000628:therapy*; D015607:Stents; D041623:Tomography, Optical Coherence
chemical_list: D018765:Dopamine Uptake Inhibitors; D003042:Cocaine