title: Aftereffects of Intense Low-Frequency Sound on Spontaneous Otoacoustic Emissions: Effect of Frequency and Level.
abstract: The presentation of intense, low-frequency (LF) sound to the human ear can cause very slow, sinusoidal oscillations of cochlear sensitivity after LF sound offset, coined the "Bounce" phenomenon. Changes in level and frequency of spontaneous otoacoustic emissions (SOAEs) are a sensitive measure of the Bounce. Here, we investigated the effect of LF sound level and frequency on the Bounce. Specifically, the level of SOAEs was tracked for minutes before and after a 90-s LF sound exposure. Trials were carried out with several LF sound levels (93 to 108 dB SPL corresponding to 47 to 75 phons at a fixed frequency of 30 Hz) and different LF sound frequencies (30, 60, 120, 240 and 480 Hz at a fixed loudness level of 80 phons). At an LF sound frequency of 30 Hz, a minimal sound level of 102 dB SPL (64 phons) was sufficient to elicit a significant Bounce. In some subjects, however, 93 dB SPL (47 phons), the lowest level used, was sufficient to elicit the Bounce phenomenon and actual thresholds could have been even lower. Measurements with different LF sound frequencies showed a mild reduction of the Bounce phenomenon with increasing LF sound frequency. This indicates that the strength of the Bounce not only is a simple function of the spectral separation between SOAE and LF sound frequency but also depends on absolute LF sound frequency, possibly related to the magnitude of the AC component of the outer hair cell receptor potential.
authors.affiliation: Division of Neurobiology, Department Biology II, University of Munich, 82152, Martinsried, Germany.
authors.forename: Lena
authors.initials: L
authors.lastname: Jeanson
authors.affiliation: Division of Neurobiology, Department Biology II, University of Munich, 82152, Martinsried, Germany.
authors.forename: Lutz
authors.initials: L
authors.lastname: Wiegrebe
authors.affiliation: German Centre for Vertigo and Balance Disorders (IFB), Grosshadern Medical Centre, University of Munich, 81377, Munich, Germany.|Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Centre, University of Munich, 81377, Munich, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Gürkov
authors.affiliation: German Centre for Vertigo and Balance Disorders (IFB), Grosshadern Medical Centre, University of Munich, 81377, Munich, Germany.|Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Centre, University of Munich, 81377, Munich, Germany.
authors.forename: Eike
authors.initials: E
authors.lastname: Krause
authors.affiliation: German Centre for Vertigo and Balance Disorders (IFB), Grosshadern Medical Centre, University of Munich, 81377, Munich, Germany. markus.drexl@med.uni-muenchen.de.|Department of Otorhinolaryngology, Head and Neck Surgery, Grosshadern Medical Centre, University of Munich, 81377, Munich, Germany. markus.drexl@med.uni-muenchen.de.
authors.forename: Markus
authors.identifier: http://orcid.org/0000-0002-0549-9846
authors.initials: M
authors.lastname: Drexl
mesh_terms: D000328:Adult; D001309:Auditory Threshold; D002118:Calcium / Q000378:metabolism; D005260:Female; D018072:Hair Cells, Auditory, Outer / Q000502:physiology; D006801:Humans; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D013016:Sound
chemical_list: D002118:Calcium
keywords: bounce phenomenon; cochlea; low-frequency sound; outer hair cells