title: Evaluating the Potential of Routine Blood Tests to Identify the Risk of Deep Vein Thrombosis: A 1-Year Monocenter Cohort Study.
abstract: Study on 295 consecutive medical patients to evaluate the potential of routine blood tests to identify the risk of deep vein thrombosis (DVT). The tests included in a DVT risk stratification model system were erythrocyte sedimentation rate, antithrombin III, C-reactive protein, D-dimer, and N-terminal pro-brain natriuretic peptide. The DVT risk stratification system was moderately prognostic (area under the curve: 0.838; 95% confidence interval: 0.771-0.904; P < .001), whereas its performance was as follows-sensitivity, 100%; specificity, 20%; positive predictive value, 21%; and negative predictive value, 100%. The prevalence of DVT and DVT + superficial thrombophlebitis was 7.5% and 3.1%, respectively. These routine blood tests may prove helpful to stratify the DVT risk in medical patients.
authors.affiliation: 1 Medical Angiology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi Hospital, Catania, Italy.
authors.forename: Salvatore Santo
authors.initials: SS
authors.lastname: Signorelli
authors.affiliation: 1 Medical Angiology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi Hospital, Catania, Italy.
authors.forename: Fiore
authors.initials: F
authors.lastname: Valerio
authors.affiliation: 1 Medical Angiology Unit, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi Hospital, Catania, Italy.
authors.forename: Castrogiovanni
authors.initials: C
authors.lastname: Davide
authors.affiliation: 2 Department of Medical, Surgical Sciences and Advanced Technologies, G.F. Ingrassia, University of Catania, Catania, Italy.
authors.forename: Gea
authors.initials: G
authors.lastname: Oliveri Conti
authors.affiliation: 2 Department of Medical, Surgical Sciences and Advanced Technologies, G.F. Ingrassia, University of Catania, Catania, Italy.
authors.forename: Fiore
authors.initials: F
authors.lastname: Maria
authors.affiliation: 3 Division of Internal Medicine Critical Areas, Garibaldi Hospital, Catania, Italy.
authors.forename: Morana
authors.initials: M
authors.lastname: Ignazio
authors.affiliation: 2 Department of Medical, Surgical Sciences and Advanced Technologies, G.F. Ingrassia, University of Catania, Catania, Italy.
authors.forename: Ferrante
authors.initials: F
authors.lastname: Margherita
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism*; D003955:Diagnostic Tests, Routine; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012306:Risk; D020246:Venous Thrombosis / Q000097:blood / Q000175:diagnosis*
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D002097:C-Reactive Protein
keywords: deep vein thrombosis; medical patients; risk; routine laboratory tests