title: Clinically Approved Nanoparticle Imaging Agents.
abstract: Nanoparticles are a new class of imaging agent used for both anatomic and molecular imaging. Nanoparticle-based imaging exploits the signal intensity, stability, and biodistribution behavior of submicron-diameter molecular imaging agents. This review focuses on nanoparticles used in human medical imaging, with an emphasis on radionuclide imaging and MRI. Newer nanoparticle platforms are also discussed in relation to theranostic and multimodal uses.
authors.affiliation: Department of Radiology, Stanford University Medical Center, Stanford, California; and.
authors.forename: Avnesh S
authors.initials: AS
authors.lastname: Thakor
authors.affiliation: Department of Nano Engineering, University of California-San Diego, San Diego, California.
authors.forename: Jesse V
authors.initials: JV
authors.lastname: Jokerst
authors.affiliation: Department of Radiology, Stanford University Medical Center, Stanford, California; and.
authors.forename: Pejman
authors.initials: P
authors.lastname: Ghanouni
authors.affiliation: Department of Radiology, Stanford University Medical Center, Stanford, California; and.
authors.forename: Jos L
authors.initials: JL
authors.lastname: Campbell
authors.affiliation: Department of Radiology, Stanford University Medical Center, Stanford, California; and.
authors.forename: Erik
authors.initials: E
authors.lastname: Mittra
authors.affiliation: Department of Radiology, Stanford University Medical Center, Stanford, California; and sgambhir@stanford.edu.
authors.forename: Sanjiv S
authors.initials: SS
authors.lastname: Gambhir
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods*; D017277:Drug Approval; D006801:Humans; D053758:Nanoparticles; D036103:Nanotechnology / Q000379:methods*
keywords: imaging and diagnostics; medical imaging; molecular imaging; nanoparticle; nanoparticles