title: The new Zero-P implant can effectively reduce the risk of postoperative dysphagia and complications compared with the traditional anterior cage and plate: a systematic review and meta-analysis.
abstract: The low-profile angle-stable spacer Zero-P is a new kind of cervical fusion system that is claimed to limit the potential drawbacks and complications. The purpose of this meta-analysis was to compare the clinical and radiological results of the new Zero-P implant with those of the traditional anterior cage and plate in the treatment of symptomatic cervical spondylosis, and provides clinicians with evidence on which to base their clinical decision making.
  
  
  
  The following electronic databases were searched: PMedline, PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, Evidence Based Medicine Reviews, VIP, and CNKI. Conference posters and abstracts were also electronically searched. The efficacy was evaluated in intraoperative time, intraoperative blood loss, fusion rate and dysphagia.
  
  
  
  For intraoperative time and intraoperative blood loss, the meta-analysis revealed that the Zero-P surgical technique is not superior to the cage and plate technique . For fusion rate, the two techniques both had good bone fusion, however, this difference is not statistically significant. For decrease of JOA and dysphagia, the pooled data showed that the Zero-P surgical technique is superior to the cage and plate technique.
  
  
  
  Zero-P interbody fusion can attain good clinical efficacy and a satisfactory fusion rate in the treatment of symptomatic cervical spondylosis. It also can effectively reduce the risk of postoperative dysphagia and its complications. However, owing to the lack of long-term follow-up, its long-term efficacy remains unknown.
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China.|Department of Bone Tumor Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
authors.forename: Mengchen
authors.initials: M
authors.lastname: Yin
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China.
authors.forename: Junming
authors.initials: J
authors.lastname: Ma
authors.affiliation: Department of Bone Tumor Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Huang
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Xia
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China.
authors.forename: Qixing
authors.initials: Q
authors.lastname: Shen
authors.affiliation: Department of Bone Tumor Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
authors.forename: Chenglong
authors.initials: C
authors.lastname: Zhao
authors.affiliation: Department of Bone Tumor Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
authors.forename: Jun
authors.initials: J
authors.lastname: Tao
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China.
authors.forename: Ni
authors.initials: N
authors.lastname: Chen
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China.
authors.forename: Zhingxing
authors.initials: Z
authors.lastname: Yu
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China.
authors.forename: Jie
authors.initials: J
authors.lastname: Ye
authors.affiliation: Department of Orthopaedics, LongHua hospital, Shanghai university of Traditional Chinese Medicine, Shanghai, People's Republic of China. mw2218@126.com.
authors.forename: Wen
authors.initials: W
authors.lastname: Mo
authors.affiliation: Department of Bone Tumor Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China. jianruxiao83@163.com.
authors.forename: Jianru
authors.initials: J
authors.lastname: Xiao
mesh_terms: D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D001860:Bone Plates / Q000009:adverse effects; D002574:Cervical Vertebrae / Q000601:surgery; D000066491:Clinical Decision-Making; D003680:Deglutition Disorders / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D016268:Internal Fixators / Q000009:adverse effects*; D061646:Operative Time; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011184:Postoperative Period; D011475:Prosthesis Failure; D011859:Radiography; D013123:Spinal Fusion / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D055009:Spondylosis / Q000601:surgery*; D016896:Treatment Outcome
keywords: Cage; Cervical spine; Cervical spondylosis; Systematic review; Zero-P plate