title: The role of growth factors in nerve regeneration.
abstract: Nerve injuries result in functional loss in the innervated organ or body parts, and recovery is difficult unless surgical treatment has been done. Different surgical treatments have been suggested for nerve repair. Tissue engineering related to growth factors has arisen as an alternative approach for triggering and improving nerve regeneration. Therefore, the aim of this review is to provide a comprehensive analysis related to growth factors as tools for optimizing the regeneration process. Studies and reviews on the use of growth factors for nerve regeneration were compiled over the course of the review. According to literature review, it may be concluded that growth factors from different sources present promising treatment related to nerve regeneration involved in neuronal differentiation, greater myelination and axonal growth and proliferation of specific cells for nerve repair.
authors.affiliation: Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayis University.
authors.forename: Mehmet Emin
authors.initials: ME
authors.lastname: Önger
authors.forename: Burcu
authors.initials: B
authors.lastname: Delibaş
authors.forename: Aysın Pınar
authors.initials: AP
authors.lastname: Türkmen
authors.forename: Erkan
authors.initials: E
authors.lastname: Erener
authors.forename: Berrin Zuhal
authors.initials: BZ
authors.lastname: Altunkaynak
authors.forename: Süleyman
authors.initials: S
authors.lastname: Kaplan
mesh_terms: D000818:Animals; D001369:Axons / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000494:pharmacology*; D009416:Nerve Regeneration / Q000187:drug effects*; D009474:Neurons / Q000166:cytology / Q000187:drug effects; D023822:Tissue Engineering
chemical_list: D036341:Intercellular Signaling Peptides and Proteins