title: Role of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of bronchogenic carcinoma: Experience of a single institution in China.
abstract: OBJECTIVE
  To evaluate diagnostic yield and the safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for mediastinal/hilar lymph nodes and intrapulmonary masses.
  
  
  METHODS
  Between July 2009 and February 2010, 95 patients with mediastinal/hilar lymphadenopathy and/or intrathoracic peritracheal or peribronchial masses detected with computed tomography underwent EBUS-TBNA. One hundred and twelve samples were obtained from lymph nodes (LNs) and 11 samples were obtained from intrapulmonary lesions. All patients had cytological evaluation by smears and/or tissue evaluation of aspiration specimens.
  
  
  RESULTS
  Out of the 95 patients, 60 had lung cancer, 58 of these patients were diagnosed using EBUS-TBNA without onsite cytology assistance, false negative in 2 cases. Sensitivity the of convex probe EBUS-TBNA method in distinguishing benign from malignant lymph nodes or thoracic mass was 96.67%. In the absence of any major complications the procedure was uneventful.
  
  
  CONCLUSIONS
  EBUS-TBNA seems a safe and effective technique in the diagnosis making bronchogenic carcinoma for mediastinal/hilar lymph nodes (LNs) and intrapulmonary masses.
authors.affiliation: Pulmonary Department, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Jiayuan
authors.initials: J
authors.lastname: Sun
authors.affiliation: Pulmonary Department, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Pulmonary Department, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Heng
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Pulmonary Department, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Shen
authors.affiliation: Pulmonary Department, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Aiqin
authors.initials: A
authors.lastname: Gu
authors.affiliation: Pulmonary Department, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Baohui
authors.initials: B
authors.lastname: Han
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D002681:China; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008875:Middle Aged
keywords: Endobronchial ultrasound; lung cancer; lymph node; transbronchial needle aspiration