title: Imaging in Axial Spondyloarthritis: Evaluation of Inflammatory and Structural Changes.
abstract: The primary use of imaging focuses on diagnostic evaluation, and pelvic radiography is still the primary modality for evaluation of disease in the sacroiliac joints. Its unreliability and inability to directly assess inflammation has led to increasing use of MRI, which directly assesses inflammatory changes as well as the structural changes associated with inflammation. Both radiography and MRI have therefore been incorporated into new classification criteria designed to capture both early and established spondyloarthritis. Fat metaplasia on T1-weighted MRI is an important intermediary tissue on the pathway from inflammation to ankylosis in both the sacroiliac joints and spine.
authors.affiliation: Department of Medicine, University of Alberta, 562 Heritage Medical Research Building, Edmonton, Alberta T6G 2S2, Canada. Electronic address: walter.maksymowych@ualberta.ca.
authors.forename: Walter P
authors.initials: WP
authors.lastname: Maksymowych
mesh_terms: D001168:Arthritis / Q000000981:diagnostic imaging*; D001853:Bone Marrow; D018450:Disease Progression; D004487:Edema / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D011859:Radiography; D012444:Saccule and Utricle; D012446:Sacroiliac Joint / Q000000981:diagnostic imaging / Q000473:pathology*; D013131:Spine / Q000000981:diagnostic imaging*; D025242:Spondylarthropathies / Q000145:classification / Q000000981:diagnostic imaging; D013167:Spondylitis, Ankylosing / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
keywords: Ankylosis; Bone edema; Erosion; Fat metaplasia; MRI; Radiography