title: [Botulinum toxin A induced protective ptosis for the treatment of recurrent epithelial defects in neurotrophic keratopathy].
abstract: In this article, a case of recurrent epithelial defects in neurotrophic keratopathy is described. Multiple abrasions of the corneal epithelium with a therapeutic contact lens, corneal stitches, and amniotic membrane transplantation in combination with artificial tears brought only short-term success. However, a botulinum toxin A induced protective ptosis could finally achieve permanent epithelial closure. As this case shows, protective ptosis can be a promising approach in spite of multiple previous ineffective therapeutic efforts.
authors.affiliation: Klinik für Augenheilkunde, Klinikum Region Hannover, Klinikum Nordstadt, Haltenhoffstr. 41, 30179, Hannover, Deutschland. alexander.schilimow@krh.eu.
authors.forename: A
authors.initials: A
authors.lastname: Schilimow
authors.affiliation: Klinik für Augenheilkunde, Klinikum Region Hannover, Klinikum Nordstadt, Haltenhoffstr. 41, 30179, Hannover, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Wiechens
mesh_terms: D001763:Blepharoptosis / Q000139:chemically induced*; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D003315:Cornea / Q000294:innervation*; D003316:Corneal Diseases / Q000628:therapy*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003929:Diabetic Neuropathies / Q000628:therapy*; D019573:Epithelium, Corneal / Q000294:innervation*; D005143:Eyelids / Q000187:drug effects; D005260:Female; D006801:Humans; D007267:Injections; D008875:Middle Aged; D011115:Polyneuropathies / Q000628:therapy*; D012008:Recurrence; D014606:Uveitis, Anterior / Q000628:therapy
chemical_list: D019274:Botulinum Toxins, Type A
keywords: Amniotic membrane transpantation; Botulinum toxin A; Corneal epithelial defects; Neurotrophic keratopathy; Protective ptosis