title: Myocardial T2 Mapping in Patients With Hypertrophic Cardiomyopathy.
abstract: OBJECTIVE
  The aim of this study was to evaluate the usefulness of T2 mapping for detecting myocardial injuries in patients with hypertrophic cardiomyopathy (HCM).
  
  
  METHODS
  Twenty-one HCM patients and 7 healthy volunteers were examined. The T2 values were measured at hyperintense areas (high-T2 areas) identified with T2 mapping, at late gadolinium enhancement (LGE) areas, and in nullified myocardium of the HCM patients. The associations between T2 values and laboratory data or LGE areas were assessed.
  
  
  RESULTS
  High-T2 areas had significantly greater T2 values than LGE areas (P < 0.05) and nullified areas (P < 0.01) of HCM and normal myocardium (P < 0.01). The presence of high-T2 areas was associated with an increase in troponin T levels (P = 0.02), and T2 values correlated with the levels of brain natriuretic peptide (P = 0.036, r = 0.86).
  
  
  CONCLUSIONS
  T2 mapping identified myocardial injuries suggested by the laboratory data in HCM.
authors.affiliation: From the *Department of Radiology, Nippon Medical School; †Department of Radiology, Nihon University Hospital, Nihon University School of Medicine; and ‡Department of Cardiology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Amano
authors.forename: Fumi
authors.initials: F
authors.lastname: Yanagisawa
authors.forename: Masaki
authors.initials: M
authors.lastname: Tachi
authors.forename: Hidenobu
authors.initials: H
authors.lastname: Hashimoto
authors.forename: Shogo
authors.initials: S
authors.lastname: Imai
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Kumita
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006321:Heart / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D005682:Gadolinium