title: Acute generalised exanthematous pustulosis (AGEP)-a potential pitfall for the acute physician.
abstract: Acute generalised exanthematous pustulosis is a rare drug-induced dermatosis with an incidence of 1-5 cases per million cases per year, characterised by the appearance of hundreds of sterile pustules over erythematous and oedematous skin. Fever and neutrophilia are usually present. It has a rapid course and usually resolves following discontinuation of the precipitating drug or as a result of topical corticosteroid treatment. A patient with AGEP, who presented with generalized pustulosis lesions after the use of Flucloxacillin for cellulitis is described, along with the management and differential diagnosis of this condition.
authors.forename: T A
authors.initials: TA
authors.lastname: Cranga
authors.forename: M A
authors.initials: MA
authors.lastname: Simpson
authors.forename: P
authors.initials: P
authors.lastname: Featherstone
mesh_terms: D000208:Acute Disease; D056150:Acute Generalized Exanthematous Pustulosis / Q000453:epidemiology* / Q000209:etiology* / Q000473:pathology; D015331:Cohort Studies; D004636:Emergency Service, Hospital; D004638:Emergency Treatment / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D035583:Rare Diseases; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D028761:Withholding Treatment