title: A Case of Simultaneous Benign Metastasizing Leiomyomas and Disseminated Peritoneal Leiomyomatosis Following Endoscopic Power Morcellation for Uterine Disease.
abstract: Extrauterine spread of leiomyomas is rare and most commonly occurs in the lungs. We present a case of simultaneous metastatic leiomyomatosis to the lungs and peritoneal cavity following laparoscopic myomectomy with power morcellation. The patient presented to our institution for further management where she underwent a robotically assisted hysterectomy with bilateral salpingo-oophorectomy. Leiomyomatous implants measuring up to 2.4 cm were resected from bowel mesentery and bladder peritoneum. Subsequent serial computed tomography imaging confirmed stable pulmonary nodules without new intraperitoneal lesions. Increasing number of cases involving extrauterine spread of leiomyomas has been reported with the introduction of power morcellation. The exact pathogenesis is unknown but is likely multifactorial. We emphasize that although the incidence of spread of benign disease is low, it is important to recognize this phenomenon as we will likely continue to encounter similar cases in the coming years.
authors.affiliation: From the Departments of *Obstetrics and Gynecology, †Pathology, and ‡Pulmonology, Mayo Clinic Arizona, Phoenix, AZ.
authors.forename: Beau Y
authors.initials: BY
authors.lastname: Park
authors.forename: Kevin O
authors.initials: KO
authors.lastname: Leslie
authors.forename: Longwen
authors.initials: L
authors.lastname: Chen
authors.forename: Laszlo T
authors.initials: LT
authors.lastname: Vaszar
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Cornella
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy; D018231:Leiomyomatosis / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D000069577:Morcellation / Q000009:adverse effects*; D010534:Peritoneal Neoplasms / Q000473:pathology / Q000556:secondary*; D014057:Tomography, X-Ray Computed; D014591:Uterine Diseases / Q000473:pathology / Q000601:surgery; D063186:Uterine Myomectomy; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*