title: Tissue Integration of a Volume-Stable Collagen Matrix in an Experimental Soft Tissue Augmentation Model.
abstract: Reducing the need for a connective tissue graft by using an efficacious biomaterial is an important task for dental professionals and patients. This experimental study aimed to test the soft tissue response to a volume-stable new collagen matrix. The device demonstrated good stability during six different time points ranging from 0 to 90 days of healing with no alteration of the wound-healing processes. The 90-day histologic specimen demonstrates eventual replacement of most of the matrix with new connective tissue fibers.
authors.forename: Luca
authors.initials: L
authors.lastname: Ferrantino
authors.forename: Dieter
authors.initials: D
authors.lastname: Bosshardt
authors.forename: Myron
authors.initials: M
authors.lastname: Nevins
authors.forename: Giacomo
authors.initials: G
authors.lastname: Santoro
authors.forename: Massimo
authors.initials: M
authors.lastname: Simion
authors.forename: David
authors.initials: D
authors.lastname: Kim
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D003094:Collagen; D003238:Connective Tissue / Q000637:transplantation*; D004285:Dogs; D008437:Maxilla / Q000601:surgery*; D008567:Membranes, Artificial; D023421:Models, Animal; D013524:Surgical Flaps; D013536:Suture Techniques; D014081:Tooth Extraction; D020390:Tooth Socket / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology*
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D003094:Collagen