title: [Sosnowsky's hogweed - toxicology and threat to health].
abstract: Sosnowsky's hogweed (Heracleum sosnowskyi Manden.) is a genus of plants in the family Apiaceae which also includes Giant Hogweed (Heracleum mantegazzianum Sommier and Levier). They are both found in Central Europe, mainly in neglected green areas or riversides. Sosnowsky's hogweed was brought to Poland from the Soviet Union in the 1950s to be used in animal feed production. Intended goals couldn't be achieved and the plant spread throughout grounds distant to the primarily cultivated lands. Sosnowsky's hogweed is especially hazardous in direct contact with human skin. It results from the content of photoallergic substances called furanocoumarins in its essential oil. Clinically it is presented as burns, mainly of 2nd and 3rd degree. They mostly occur on the face, upper and lower limbs. Typical symptoms include pain, redness, swelling and heat in the area of exposure. Their extent depends on burn's depth and area and also on time of exposure to plant's toxins. In this article we present Sosnowsky's hogweed's activity and its influence on human health.
authors.affiliation: Medical University of Wrocław, Poland: Faculty of Postgraduate Medical Training, Department and Clinic of Endocrinology, Diabetology and Isotope Therapy.
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Zdrojewicz
authors.affiliation: Medical University of Wrocław, Poland: Faculty of Medicine.
authors.forename: Marek
authors.initials: M
authors.lastname: Stebnicki
authors.affiliation: Medical University of Wrocław, Poland: Faculty of Medicine.
authors.forename: Michał
authors.initials: M
authors.lastname: Stebnicki
mesh_terms: D011564:Furocoumarins / Q000009:adverse effects / Q000633:toxicity*; D030002:Heracleum / Q000737:chemistry* / Q000633:toxicity; D006801:Humans; D017319:Photosensitizing Agents / Q000009:adverse effects / Q000633:toxicity*; D013471:Sunburn / Q000209:etiology*
chemical_list: D011564:Furocoumarins; D017319:Photosensitizing Agents
keywords: Heracleum sosnowskyi; Sosnowsky’s hogweed; burns; furanocoumarins