title: Severe Neck and Face Edema in an Adolescent-Delayed Hypersensitivity Reaction to Hair Dye.
abstract: Allergic contact reactions to hair dyes arise mostly due to sensitization to para-phenylenediamine (PPD). Para-phenylenediamine, a derivative of p-nitroanaline, is widely used as an oxydizable hair dye and is also found in black henna tattoo. Subsequent exposure to PPD may lead to delayed type IV hypersensitivity reaction manifesting as acute contact dermatitis. Here, a 15-year-old girl is presented, who developed a hypersensitivity reaction after first exposure to hair dye. She was found to have been sensitized to PPD before, through application of black henna tatto.
authors.affiliation: From the *Department of Pediatric Allergy and †Department of Pediatric Allergy and Immunology, Dokuz Eylul University Hospital, Izmir, Turkey.
authors.forename: Sakine
authors.initials: S
authors.lastname: Işik
authors.forename: Sule
authors.initials: S
authors.lastname: Caglayan-Sözmen
authors.forename: Özden
authors.initials: Ö
authors.lastname: Anal
authors.forename: Özkan
authors.initials: Ö
authors.lastname: Karaman
authors.forename: Nevin
authors.initials: N
authors.lastname: Uzuner
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000799:Angioedema / Q000150:complications / Q000209:etiology; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D004487:Edema / Q000150:complications* / Q000209:etiology; D005145:Face / Q000473:pathology*; D005260:Female; D006202:Hair Dyes / Q000009:adverse effects*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D009333:Neck / Q000473:pathology*; D010328:Patch Tests / Q000379:methods; D010655:Phenylenediamines / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D006202:Hair Dyes; D010655:Phenylenediamines; C029728:4-phenylenediamine