title: Outcomes of off-pump versus on-pump coronary artery bypass graft surgery in patients with severely dilated left ventricle.
abstract: BACKGROUND
  Currently, off-pump coronary artery bypass (OPCAB) grafting has been the standard procedure for surgical revascularization in patients with coronary artery disease (CAD). This study aimed to examine the safety and applicability of OPCAB compared with on-pump coronary artery bypass (ONCAB) in patients with severely dilated left ventricle.
  
  
  METHODS
  A retrospective study of giant left ventricle patients [left ventricular end diastolic diameter (LVEDD) ≥ VE mm] undergoing coronary bypass grafting from 2009 through 2015 at a single center was conducted. Preoperative and intraoperative risk factors, and postoperative outcomes were analyzed. Survival analysis was carried to analyze survival rate during follow-up.
  
  
  RESULTS
  A total of 24 patients underwent ONCAB, and 26 underwent OPCAB. Both groups had similar preoperative profiles. Two cases from each group died during in-hospital time. In comparison to OPCAB, there was longer operation and post-surgery intubation time and more renal dysfunction in ONCAB group (P<0.05). One-year survival between OPCAB and ONCAB were not significantly different (87.5%vs. 92.3%, P>0.05).
  
  
  CONCLUSIONS
  OPCAB is a safe and feasible alternative for CAD patients with giant left ventricle, offering a significant advantage over ONCAB with regards to renal function, operation duration and length of ventilation.
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Sen
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Wenhui
authors.initials: W
authors.lastname: Gong
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Qi
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Zezhe
authors.initials: Z
authors.lastname: Yuan
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Anqing
authors.initials: A
authors.lastname: Chen
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Junfeng
authors.initials: J
authors.lastname: Cai
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Mi
authors.initials: M
authors.lastname: Zhou
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Ye
authors.affiliation: Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School, Shanghai 200025, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhao
keywords: Dilated left ventricle; coronary artery bypass grafting (CABG); coronary artery disease (CAD)