title: Airway Management in a Patient with Wolf-Hirschhorn Syndrome.
abstract: We present a case of a 3-month-old female with Wolf-Hirschhorn syndrome (WHS) undergoing general anesthesia for laparoscopic gastrostomy tube placement with a focus on airway management. WHS is a rare 4p microdeletion syndrome resulting in multiple congenital abnormalities, including craniofacial deformities. Microcephaly, micrognathia, and glossoptosis are common features in WHS patients and risk factors for a pediatric airway that is potentially difficult to intubate. We discuss anesthesia strategies for airway preparation and management in a WHS patient requiring general anesthesia with endotracheal intubation.
authors.affiliation: Department of Anesthesiology, Duke University Medical Center, DUMC 3094, Durham, NC 27710, USA.
authors.forename: John F
authors.identifier: 0000-0002-1587-1541
authors.initials: JF
authors.lastname: Gamble
authors.affiliation: Department of Anesthesiology, Duke University Medical Center, DUMC 3094, Durham, NC 27710, USA.
authors.forename: Dinesh J
authors.identifier: 0000-0003-1158-3232
authors.initials: DJ
authors.lastname: Kurian
authors.affiliation: Department of Anesthesiology, Duke University Medical Center, DUMC 3094, Durham, NC 27710, USA.
authors.forename: Andrea G
authors.initials: AG
authors.lastname: Udani
authors.affiliation: Department of Anesthesiology, Duke University Medical Center, DUMC 3094, Durham, NC 27710, USA.
authors.forename: Nathaniel H
authors.identifier: 0000-0003-0230-0499
authors.initials: NH
authors.lastname: Greene