title: HSFY and ZNF280BY show copy number variations within 17 water buffalo populations.
abstract: Recent transcriptomic analysis of the bovine Y chromosome revealed abundant presence of multi-copy protein coding gene families on the male-specific region of the Y chromosome (MSY). Copy number variations (CNVs) of several MSY genes are closely related to semen quality and male reproduction in cattle. However, the CNVs of MSY genes in water buffalo are largely unknown. Therefore, this study aimed to investigate the CNVs of HSFY and ZNF280BY of 298 buffaloes from 17 populations distributed in China, Vietnam and Laos using quantitative PCR. Our results revealed that the median copy numbers of the HSFY and ZNF280BY genes were 47 (ranging from 20 to 145) and 269 (ranging from 73 to 974) respectively. In conclusion, this study indicated that HSFY and ZNF280BY showed abundant CNVs within swamp buffalo populations.
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: H
authors.initials: H
authors.lastname: Han
authors.affiliation: Shaanxi University of Technology, Hanzhong, Shaanxi, 723001, China.
authors.forename: T
authors.initials: T
authors.lastname: Zhang
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: T
authors.initials: T
authors.lastname: Sun
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Xi
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: N
authors.initials: N
authors.lastname: Chen
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: R
authors.initials: R
authors.lastname: Dang
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: X
authors.initials: X
authors.lastname: Lan
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.affiliation: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
authors.forename: C
authors.initials: C
authors.lastname: Lei
mesh_terms: D000818:Animals; D002020:Buffaloes / Q000097:blood / Q000145:classification / Q000235:genetics*; D002681:China; D056915:DNA Copy Number Variations; D005260:Female; D008297:Male; D011153:Population; D015534:Trans-Activators / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*; D014744:Vietnam; D014998:Y Chromosome
chemical_list: D015534:Trans-Activators; D014157:Transcription Factors
keywords: Y-linked genes; buffalo; copy number variations; multi-copy genes