title: G2 arrest of cell cycle ensures a determination process of sensory mother cell formation in Drosophila.
abstract: In Drosophila, the sensory mother cells of macrochaetes are chosen from among the mitotically quiescent clusters of cells in wing imaginal discs, where other cells are proliferating. The pattern of cyclin A, one of the G2 cyclins, reveals that mitotically quiescent clusters of cells are arrested in G2. When precocious mitoses are induced during sensory mother cell determination by the ectopic expression of string, a known G2/M transition regulator, the formation of sensory mother cells is disturbed, resulting in the loss of macrochaetes in the adult notum. This suggests that G2 arrest of the cell cycle ensures the proper determination of sensory mother cells.
authors.affiliation: Laboratory of Biology, Iwamizawa Campus, Hokkaido University of Education, Iwamizawa 068, Japan, , , , , , JP.
authors.forename: K
authors.initials: K
authors.lastname: Kimura
authors.affiliation: Laboratory of Biology, Iwamizawa Campus, Hokkaido University of Education, Iwamizawa 068, Japan, , , , , , JP.
authors.forename: Akiko
authors.initials: A
authors.lastname: Usui-Ishihara
authors.affiliation: Laboratory of Biology, Iwamizawa Campus, Hokkaido University of Education, Iwamizawa 068, Japan, , , , , , JP.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Usui
keywords: Cyclin A; Determination; Drosophila; Key words Cell cycle; Sensory mother cell