title: [Clinical features of respiratory distress syndrome in neonates of different gestational ages].
abstract: OBJECTIVE
  To study clinical features of respiratory distress syndrome (RDS) in neonates of different gestational ages (GA).
  
  
  METHODS
  According to GA, 133 neonates with RDS were classified into GA <34 weeks group (n=66), GA 34-36 weeks group (late preterm neonates; n=31), and GA ≥37 weeks group (full-term neonates; n=36). The mothers' medical history during pregnancy and the condition of the neonates at birth were retrospectively analyzed, and the clinical data were compared between groups.
  
  
  RESULTS
  Prenatal corticosteroids supplementation in the GA <34 weeks group was more common than that in the GA 34-36 weeks group (P<0.05). Compared with the GA ≥37 weeks group and the GA 34-36 weeks group, the GA <34 weeks group showed a significantly lower rate of primary diseases, a significantly later time of the development of dyspnea (P<0.05), and a higher rate of intraventricular hemorrhage (P<0.05). Serum albumin levels in the GA <34 weeks group were significantly lower than in the GA ≥37 weeks group (P<0.05). The GA ≥37 weeks group and the GA 34-36 weeks group showed a significantly higher reuse rate of pulmonary surfactant (P<0.05). Use of high-frequency oscillatory ventilation was more common in the GA ≥37 weeks group compared with the GA <34 weeks group (P<0.05).
  
  
  CONCLUSIONS
  The clinical features of RDS are different across neonates of different GA, suggesting that the pathogenesis of RDS may be different in neonates of different GA.
authors.affiliation: Department of Pediatrics, Sichuan Academy of Medical Sciences/Sichuan Provincial People's Hospital, Chengdu 610072, China. chen966888@aliyun.com.
authors.forename: Mao-Jun
authors.initials: MJ
authors.lastname: Li
authors.forename: Qing
authors.initials: Q
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: Shi
authors.forename: Qian
authors.initials: Q
authors.lastname: Yang
authors.forename: Bin-Zhi
authors.initials: BZ
authors.lastname: Tang
authors.forename: Chang-Hui
authors.initials: CH
authors.lastname: Chen
mesh_terms: D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012127:Respiratory Distress Syndrome, Newborn / Q000097:blood / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012709:Serum Albumin / Q000032:analysis
chemical_list: D012709:Serum Albumin