title: Insights in Hypothesis Testing and Making Decisions in Biomedical Research.
abstract: It is a fact thatpvalues are commonly used for inference in biomedical and other social fields of research. Unfortunately, the role ofpvalue is very often misused and misinterpreted; that is why it has been recommended the use of resampling methods, like the bootstrap method, to calculate the confidence interval, which provides more robust results for inference than doespvalue. In this review a discussion is made about the use ofpvalues through hypothesis testing and its alternatives using resampling methods to develop confidence intervals of the tested statistic or effect measure.
authors.affiliation: Collège de Villamont, Lausanne, Switzerland.
authors.forename: Varin
authors.initials: V
authors.lastname: Sacha
authors.affiliation: School of Health Science and Education, Harokopio University, Athens, Greece.
authors.forename: Demosthenes B
authors.initials: DB
authors.lastname: Panagiotakos
keywords: Biostatistics; Confidence intervals; Evidence based medicine; Resampling; p value