title: Polyostotic Fibrous Dysplasia in McCune-Albright Syndrome Demonstrated on 68Ga-DOTATATE PET/CT.
abstract: A 33-year-old woman with McCune-Albright syndrome was referred for a Ga-DOTATATE PET/CT study for evaluation and staging of a biopsy-proven pancreatic tail neuroendocrine tumor. The scan demonstrated intense focal octreopeptide uptake corresponding to the known neuroendocrine tumor at the pancreatic tail/splenic hilum. There was no evidence of octreopeptide-avid metastases. Diffuse octreopeptide uptake was demonstrated in multiple bones involving the right side of the skeleton. The concurrent CT demonstrated corresponding expansile lucent changes consistent with the known fibrous dysplasia.
authors.affiliation: From the *Nuclear Medicine and PET Department, Nepean Hospital, Penrith; and †Nepean Medical School, University of Sydney, New South Wales, Australia.
authors.forename: Grace
authors.initials: G
authors.lastname: Hennessy
authors.forename: Deepa
authors.initials: D
authors.lastname: Shetty
authors.forename: Han
authors.initials: H
authors.lastname: Loh
authors.forename: Chuong
authors.initials: C
authors.lastname: Bui
authors.forename: Ken
authors.initials: K
authors.lastname: Le
authors.forename: Robert
authors.initials: R
authors.lastname: Mansberg
mesh_terms: D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging; D005260:Female; D005359:Fibrous Dysplasia, Polyostotic / Q000000981:diagnostic imaging*; D006801:Humans; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging; D009942:Organometallic Compounds / Q000008:administration & dosage; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000008:administration & dosage
chemical_list: D009942:Organometallic Compounds; D019275:Radiopharmaceuticals; C513399:gallium Ga 68 dotatate