title: Comparison of short-term refractive surgery outcomes after wavefront-guided versus non-wavefront-guided LASIK.
abstract: OBJECTIVE
  To evaluate and compare visual and refractive outcomes after laser-assisted in situ keratomileusis (LASIK) surgery for the correction of myopia or myopic astigmatism using 3 different treatment protocols.
  
  
  METHODS
  We included 736 eyes of 369 patients (age 18-62 years) divided into 3 groups: 235 eyes of 118 patients (MEL80 group) undergoing LASIK using optimized aspheric ablation profiles (MEL80 excimer laser; Carl Zeiss Meditec), 248 eyes of 124 patients (Wavescan group) undergoing wavefront-guided (WFG) LASIK (STAR S4IR excimer laser + Wavescan aberrometer; Abbott Medical Optics), and 253 eyes of 127 patients (iDesign group) undergoing WFG LASIK (STAR S4IR excimer laser + iDesign system; Abbott Medical Optics). Visual and refractive outcomes were evaluated 2 months after surgery.
  
  
  RESULTS
  A total of 91% (215/235), 95% (237/248), and 99% (251/253) of eyes achieved a postoperative uncorrected distance visual acuity of 0.0 logMAR (≈20/20) in the MEL80, Wavescan, and iDesign groups, respectively. Postoperative spherical equivalent (SE) was within ±0.5 D in 95% (223/235), 98% (242/248), and 100% (253/253) of eyes in these same 3 groups, respectively. Likewise, manifest cylinder was below 0.50 D in 95% (223/235), 97% (241/248), and 100% (253/253) of eyes. Significant differences in postoperative SE and cylinder were found between the MEL80 and iDesign groups (p&lt;0.05).
  
  
  CONCLUSIONS
  All evaluated LASIK treatment protocols are predictable and effective for the correction of myopia. The treatment planned with a high resolution aberrometer obtained the best postoperative refractive outcomes.
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria.
authors.forename: Sarah
authors.initials: S
authors.lastname: Moussa
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria.
authors.forename: Alois
authors.initials: A
authors.lastname: Dexl
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria.
authors.forename: Eva Maria
authors.initials: EM
authors.lastname: Krall
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria.
authors.forename: Marie
authors.initials: M
authors.lastname: Dietrich
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria.
authors.forename: Eva-Maria
authors.initials: EM
authors.lastname: Arlt
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria.
authors.forename: Günther
authors.initials: G
authors.lastname: Grabner
authors.affiliation: Department of Ophthalmology and Optometry, Paracelsus Medical University of Salzburg, Salzburg - Austria.
authors.forename: Josef
authors.initials: J
authors.lastname: Ruckhofer
mesh_terms: D057128:Aberrometry; D000293:Adolescent; D000328:Adult; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology*; D012189:Retrospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult