title: Olympic Genes on the Podium?
abstract: Despite some advances, it remains largely unknown how the millions of variations in the human genome influence athletic performance (especially in endurance events), and no single genetic test can really predict sports talent. However, there is experimental evidence from animal research that selecting for even a simple characteristic such as running ability can produce comparatively large and rapid changes in performance. That such selection has not been specifically documented in humans is more evidence of the limits of physiology-archeology than of the unlikelihood of selection for physical abilities. Here, the authors argue that top Olympians are likely genetically gifted individuals who in addition have numerous contributors to the "complex trait" of being an athletic champion that may not necessarily depend on defined genetic variations.
authors.forename: Fabian
authors.initials: F
authors.lastname: Sanchis-Gomar
authors.forename: Helios
authors.initials: H
authors.lastname: Pareja-Galeano
authors.forename: Jose A
authors.initials: JA
authors.lastname: Rodriguez-Marroyo
authors.forename: Jos J
authors.initials: JJ
authors.lastname: de Koning
authors.forename: Alejandro
authors.initials: A
authors.lastname: Lucia
authors.forename: Carl
authors.initials: C
authors.lastname: Foster
mesh_terms: D001076:Aptitude; D054874:Athletic Performance / Q000502:physiology*; D003163:Competitive Behavior / Q000502:physiology; D005838:Genotype; D006801:Humans; D011110:Polymorphism, Genetic
keywords: athlete; genomic variants; performance; sport