title: RELATIONSHIP BETWEEN THE PRESENCE OF HELICOBACTER PYLORI WITH INFLAMMATORY ENDOSCOPIC CHANGES IN GASTRODUODENAL MUCOSA.
abstract: The influence of Helicobacter pylori (HP) in inflammatory disorders of the digestive mucosa has been the subject of several studies since socioeconomic, personal and environmental factors were implicated in the bacteria transmission.
  
  
  
  To correlate the inflammatory endoscopic findings with HP infection and the onset of mucosal diseases mucous of the upper digestive tract.
  
  
  
  Comparative observational study, in which were collected data from 2247 patients who underwent upper endoscopy and biopsies for HP with urease test. The patients were divided into two groups: HP+ and HP- (control) in which endoscopic findings were observed for the following changes: esophagitis, esophageal ulcer, gastritis, erosive gastritis, gastric ulcer, bulboduodenitis, bulbar ulcer and without disease.
  
  
  
  As for esophagitis, there was little disparity in the distribution favorable to HP+ group (HP+ =67.11% and HP- =69.89%) and esophageal ulcer (HP+ =0% and HP- =0, 21%). Gastritis was favorable to HP- group (HP+ =78.34% and HP- =73.63%), as well as erosive gastritis (HP+ = 67,11% and HP- = 64,55%), in bulboduodenitis (HP+ =1,87% and HP- 1,23%), in gastric ulcer (HP+ =2,14% and HP- =2,03%) and in the absence of alterations in the HP+ group (4.81%) with the HP- control group (6,30%), in which there was little disproportion in favor of HP- group, but without statistical significance. As for the bulbar ulcer (HP +=10.16% and HP- =4.48%), there was statistically significant (p=0.00001).
  
  
  
  There is no difference between HP+ and HP- groups in inflammatory changes in endoscopic gastroduodenal mucosa, except for the relationship between HP and bulbar ulcer.
authors.affiliation: Postgraduate Program in Principles of Surgery, Evangelic Faculty of Paraná/University Evangelic Hospital of Curitiba/Medical Research Institute, Curitiba, PR, Brazil.|Gastrointestinal Endoscopy Service, 9 of July Hospital, São Paulo, SP, Brazil.
authors.forename: Irma Cláudia Saboya
authors.initials: IC
authors.lastname: Ribeiro
authors.affiliation: Postgraduate Program in Principles of Surgery, Evangelic Faculty of Paraná/University Evangelic Hospital of Curitiba/Medical Research Institute, Curitiba, PR, Brazil.
authors.forename: Luiz Fernandao
authors.initials: LF
authors.lastname: Kubrusly
authors.affiliation: Postgraduate Program in Principles of Surgery, Evangelic Faculty of Paraná/University Evangelic Hospital of Curitiba/Medical Research Institute, Curitiba, PR, Brazil.
authors.forename: Paulo Afonso Nunes
authors.initials: PA
authors.lastname: Nassif
authors.affiliation: Gastrointestinal Endoscopy Service, 9 of July Hospital, São Paulo, SP, Brazil.
authors.forename: Patrícia Fernanda Saboya
authors.initials: PF
authors.lastname: Ribeiro
authors.affiliation: Postgraduate Program in Principles of Surgery, Evangelic Faculty of Paraná/University Evangelic Hospital of Curitiba/Medical Research Institute, Curitiba, PR, Brazil.
authors.forename: Rodrigo de Oliveira
authors.initials: RO
authors.lastname: Veras
authors.affiliation: Postgraduate Program in Principles of Surgery, Evangelic Faculty of Paraná/University Evangelic Hospital of Curitiba/Medical Research Institute, Curitiba, PR, Brazil.
authors.forename: Aline
authors.initials: A
authors.lastname: Neppel
mesh_terms: D000328:Adult; D004382:Duodenitis / Q000382:microbiology* / Q000473:pathology*; D004384:Duodenoscopy; D004941:Esophagitis / Q000382:microbiology* / Q000473:pathology*; D005260:Female; D005753:Gastric Mucosa / Q000382:microbiology* / Q000473:pathology*; D005756:Gastritis / Q000382:microbiology* / Q000473:pathology*; D005773:Gastroscopy; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007413:Intestinal Mucosa / Q000382:microbiology* / Q000473:pathology*; D008297:Male