title: [Study of the Immunological Stress Caused by Breast Surgery Methods].
abstract: To determine the role of immunosuppressive acidic protein(IAP)in the host defense of surgical patients, we investigated the kinetics of the post-operative elevation of IAP, as well as factors influencing the increase in serum IAP concentration, in 17 patients who underwent breast surgery. IAP was not increased in the pre-operation phase, post-operation phase, or 2 weeks after surgery, byvarious breast surgerymethods. In contrast, IL-6 was increased in the post-operation phase byall breast surgerymethods. IL-6 correlated with anesthesia time. These results suggest that breast surgical methods are less immunologicallyinvasive than other major surgery.
authors.affiliation: Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Hirano
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sakurai
authors.forename: Shigeru
authors.initials: S
authors.lastname: Fujisaki
authors.forename: Keita
authors.initials: K
authors.lastname: Adachi
authors.forename: Shuhei
authors.initials: S
authors.lastname: Suzuki
authors.forename: Yuki
authors.initials: Y
authors.lastname: Masuo
authors.forename: Saki
authors.initials: S
authors.lastname: Nagashima
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Hara
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Enomoto
authors.forename: Ryouichi
authors.initials: R
authors.lastname: Tomita
authors.forename: Kenji
authors.initials: K
authors.lastname: Gonda
mesh_terms: D001943:Breast Neoplasms / Q000276:immunology* / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000601:surgery*; D008207:Lymphatic Metastasis; D008408:Mastectomy / Q000379:methods*; D008875:Middle Aged; D013312:Stress, Physiological
chemical_list: C508600:IL6 protein, human; D015850:Interleukin-6