title: Primary monophasic synovial sarcoma of the pleura: Neoadjuvant chemotherapy followed by complete resection.
abstract: We describe a rare case of primary pleural synovial sarcoma in a 27-year-old man with a 4-month history of dry cough and left-sided chest pain. A CT scan showed a large cystic mass in the left pleural cavity. The patient underwent two video-assisted thoracoscopic biopsies and the diagnosis of synovial sarcoma of the pleura was established. After neoadjuvant chemotherapy, which resulted in a partial response, the tumor was completely resected with extrapleural pneumonectomy. Pathological findings showed less than 5% of viable cancer and free surgical margins. The patient is clinically well 24 months after surgery, with no evidence of recurrent disease.
authors.affiliation: Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.
authors.forename: Ramiro G M
authors.initials: RG
authors.lastname: Silva
authors.affiliation: Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.
authors.forename: Jefferson L
authors.initials: JL
authors.lastname: Gross
authors.affiliation: Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.
authors.forename: Rodrigo A
authors.initials: RA
authors.lastname: Silva
authors.affiliation: Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.
authors.forename: Fabio J
authors.initials: FJ
authors.lastname: Haddad
authors.affiliation: Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.
authors.forename: Riad N
authors.initials: RN
authors.lastname: Younes
authors.affiliation: Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.
authors.forename: Vasco M
authors.initials: VM
authors.lastname: Cruz
authors.affiliation: Surgical Oncology, A.C. Camargo Hospital, São Paulo, Brazil Department of Thoracic Surgery, A.C. Camargo Hospital, São Paulo, Brazil.
authors.forename: Antonio B M
authors.initials: AB
authors.lastname: Avertano-Rocha
keywords: Immunochemistry; pleura; pneumonectomy; synovial sarcoma