title: Seven years of radionuclide laboratory at IMC - important achievements.
abstract: For many important research topics in polymer science the use of radionuclides brings significant benefits concerning nanotechnology, polymer drug delivery systems, tissue engineering etc. This contribution describes important achievements of the radionuclide laboratory at Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic (IMC) in the area of polymers for biomedical applications. Particular emphasis will be given to water-soluble polymer carriers of radionuclides, thermoresponsive polymer radionuclide carriers, thermoresponsive polymers for local brachytherapy, polymer scaffolds modified with (radiolabeled) peptides and polymer copper chelators for the therapy of Wilson´s disease.
authors.affiliation: Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic. mhruby@centrum.cz.
authors.forename: M
authors.initials: M
authors.lastname: Hrubý
authors.forename: J
authors.initials: J
authors.lastname: Kučka
authors.forename: J
authors.initials: J
authors.lastname: Pánek
authors.forename: P
authors.initials: P
authors.lastname: Štěpánek
mesh_terms: D001918:Brachytherapy; D002614:Chelating Agents / Q000627:therapeutic use; D003300:Copper / Q000302:isolation & purification; D004337:Drug Carriers; D006527:Hepatolenticular Degeneration / Q000188:drug therapy; D006801:Humans; D010455:Peptides; D011108:Polymers; D011868:Radioisotopes
chemical_list: D002614:Chelating Agents; D004337:Drug Carriers; D010455:Peptides; D011108:Polymers; D011868:Radioisotopes; D003300:Copper