title: Association of Chlamydia pneumoniae immunoglobulin G antibodies with the risk of lung cancer among non-smoking women in Liaoning, China.
abstract: The role of Chlamydia pneumoniae in the cause of lung cancer is controversial. In this study, we investigated the association between C. pneumoniae immunoglobulin (Ig) G antibodies and risk of lung cancer among non-smoking women. C. pneumoniae IgG antibody levels were compared between 192 adult Chinese women who met the diagnostic criteria of lung cancer and 90 healthy controls. C. pneumoniae IgG antibodies were tested with the use of an enzyme-linked immunosorbent assay. The prevalence of C. pneumoniae IgG seropositivity was 61.98% of cases and 28.89% of controls (P < 0.05). According to the results of the multiple logistic analysis model, the odds ratios for C. pneumoniae IgG antibody seropositivity, body mass index, and educational levels were 3.919 (P < 0.001), 0.731 (P= 0.274), and 1.646 (P= 0.069), respectively. C. pneumoniae infection may be a risk factor for lung cancer.
authors.affiliation: Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China Liaoning Provincial Tumor Hospital, Shenyang, China Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Zhuang
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China Liaoning Provincial Tumor Hospital, Shenyang, China Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Su
authors.affiliation: Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China Liaoning Provincial Tumor Hospital, Shenyang, China Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Shi-Cheng
authors.initials: SC
authors.lastname: Yu
authors.affiliation: Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China Liaoning Provincial Tumor Hospital, Shenyang, China Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Yin
authors.affiliation: Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China Key Laboratory of Cancer Etiology and Intervention, University of Liaoning Province, Shenyang, China Liaoning Provincial Tumor Hospital, Shenyang, China Chinese Center for Disease Control and Prevention, Beijing, China.
authors.forename: Bao-Sen
authors.initials: BS
authors.lastname: Zhou
keywords: Chlamydia pneumoniae IgG antibodies; immunoglobulin; lung cancer