title: Detection and Prevention of Cognitive Decline.
abstract: Current diagnostic and treatment strategies for cognitive decline can help patients maintain cognitive ability and higher levels of function longer. Despite advances in detection and early treatment strategies, many patients do not receive proper assessments and available therapies. A systematic assessment strategy will increase the likelihood of an accurate diagnosis, which can facilitate pharmacologic and non-pharmacologic treatment plans that can have a meaningful impact on prognosis. Available data support the integration of healthy lifestyle strategies in the treatment plan to help to stabilize symptoms and potentially delay future cognitive decline. While investigators continue to pursue more effective detection, treatment, and prevention strategies, the scientific data support the use of symptomatic drug treatments and recommendations for healthy lifestyle behaviors to improve quality of life and potentially stave off future cognitive decline. Success of such healthy lifestyle programs involves educating participants on the connection between lifestyle and disease prevention, offering enjoyable exercises that target the patient's skill level, and providing feedback that motivates participants to continue their healthy behaviors so they become habits.
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, The UCLA Longevity Center, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA. Electronic address: gsmall@mednet.ucla.edu.
authors.forename: Gary W
authors.initials: GW
authors.lastname: Small
mesh_terms: D000368:Aged; D015415:Biomarkers; D060825:Cognitive Dysfunction / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics / Q000517:prevention & control; D003704:Dementia / Q000175:diagnosis / Q000517:prevention & control; D006801:Humans; D018697:Nootropic Agents / Q000627:therapeutic use; D011379:Prognosis; D040242:Risk Reduction Behavior
chemical_list: D015415:Biomarkers; D018697:Nootropic Agents
keywords: cognitive decline; diagnosis; prevention; treatment