title: Infection in Bone Allograft Transplants.
abstract: Bone allografts are widely being used in clinical practice for bone reconstruction. They are considered to be the most preferred alternative to bone autografts, mainly due to their availability and the elimination of donor site morbidity. The risk of bacterial and viral disease transmission, albeit low, is one of the major concerns associated with bone allograft transplant. This review focuses on the epidemiologic and microbiologic aspects of bone allograft infections and the current prevention and treatment options. It also discusses the role of the regulatory authorities in ensuring the safety and efficacy of bone allografts.
authors.affiliation: From the Department of Orthopaedics, Faculty of Medicine, Comenius University in Bratislava and Children's University Hospital, Bratislava, Slovak Republic and the Institute of Anatomy, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
authors.forename: Radoslav
authors.initials: R
authors.lastname: Zamborsky
authors.forename: Andrey
authors.initials: A
authors.lastname: Svec
authors.forename: Martin
authors.initials: M
authors.lastname: Bohac
authors.forename: Miroslav
authors.initials: M
authors.lastname: Kilian
authors.forename: Milan
authors.initials: M
authors.lastname: Kokavec
mesh_terms: D064591:Allografts; D001424:Bacterial Infections / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control / Q000635:transmission; D016025:Bone Transplantation / Q000009:adverse effects*; D046148:Donor Selection; D006801:Humans; D009926:Organ Preservation; D018570:Risk Assessment; D012307:Risk Factors; D020858:Tissue and Organ Harvesting; D016896:Treatment Outcome; D014777:Virus Diseases / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission / Q000821:virology*