title: Calcified synovial metastasis in the knee from renal cell carcinoma: a case report.
abstract: We present the case of an 83-year-old man who had painful swelling of right knee for 6 months. Radiographs showed a large intra-articular soft-tissue mass with small calcifications, whereas MRI detected a multilobulated intra-articular tumor with bone erosions at the distal femur. Histopathology of ultrasound-guided biopsy specimen of the synovial mass revealed it to be a poorly differentiated metastatic carcinoma. Abdominal computed tomography with intravenous contrast medium administration found a heterogeneously enhancing large right renal mass with calcifications, which was shown to be a renal cell carcinoma on histopathology. No metastases were found elsewhere. To our knowledge, this is the first reported case with MRI findings of a calcified intra-articular synovial metastasis from renal cell carcinoma.
authors.affiliation: Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515- Holcombe Blvd, Unit 1475, Houston, TX, 77030, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: McConnell
authors.affiliation: Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515- Holcombe Blvd, Unit 1475, Houston, TX, 77030, USA. radiokumar@hotmail.com.
authors.forename: Rajendra
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515- Holcombe Blvd, Unit 1475, Houston, TX, 77030, USA.
authors.forename: Behrang
authors.initials: B
authors.lastname: Amini
authors.affiliation: Department of Orthopaedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors.forename: Patrick P
authors.initials: PP
authors.lastname: Lin
authors.affiliation: Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors.forename: Wei-Lien
authors.initials: WL
authors.lastname: Wang
mesh_terms: D000369:Aged, 80 and over; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000556:secondary*; D003287:Contrast Media; D003937:Diagnosis, Differential; D006801:Humans; D061705:Image-Guided Biopsy; D007680:Kidney Neoplasms / Q000473:pathology*; D007719:Knee Joint; D008279:Magnetic Resonance Imaging; D008297:Male; D013584:Sarcoma, Synovial / Q000000981:diagnostic imaging* / Q000556:secondary*
chemical_list: D003287:Contrast Media
keywords: Calcified intra-articular metastasis; Calcified renal cell carcinoma; Calcified synovial tumor; Synovial metastasis