title: Impact of early-onset peritonitis on mortality and technique survival in peritoneal dialysis patients.
abstract: BACKGROUND
  Early onset peritonitis (EOP) is not uncommon in peritoneal dialysis patients. We aimed to compare the prognosis of EOP and non-EOP peritoneal dialysis patients.
  
  
  METHODS
  This study included subjects that underwent PD from January 1, 2004 to July 31, 2013. Patient characteristics were collected. EOP was defined as peritonitis occurring within 6 months after initiation of PD. Patient and technique survival were compared between EOP and non-EOP patients using Cox regression analyses.
  
  
  RESULTS
  In total, 189 subjects were included in this study. Patients were divided into EOP (n = 55) and non-EOP groups (n = 134). There was no significant difference in the causative organisms of peritonitis between the two groups. After adjusting for age, diabetes status, serum albumin level and residual renal function, the multivariable Cox regression model revealed that EOP was an independent risk factor for patient mortality (HR 2.03, RI 1.09-3.80, p = 0.026), technique failure (HR 1.69, RI 1.12-2.87, p = 0.015) and total survival (HR 1.73, RI 1.12-2.68, p = 0.013).
  
  
  CONCLUSIONS
  EOP was identified as an independent risk factor for mortality and technique failure in peritoneal dialysis patients.
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Feng
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Yancai
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Beifen
authors.initials: B
authors.lastname: Qiu
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Linseng
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Zhoubing
authors.initials: Z
authors.lastname: Zhan
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Shan
authors.initials: S
authors.lastname: Jiang
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Jinchang, Suzhou, 215000 Jiangsu China.
authors.forename: Huaying
authors.initials: H
authors.lastname: Shen
keywords: Early onset peritonitis; Mortality; Peritoneal dialysis