title: Reconstruction for Skull Base Defect Using Fat-Containing Perifascial Areolar Tissue.
abstract: Skull base reconstruction is a challenging task. The method depends on the anatomical complexity and size of the defect. We obtained tissue by harvesting fat-containing perifascial areolar tissue (PAT) for reconstruction of limited skull base defects and volume augmentation. We demonstrated the effective option for reconstruction of limited skull base defects and volume augmentation. From October 2013 to November 2015, 5 patients underwent operations using fat-containing PAT to fill the defect in skull base and/or perform volume replacement in the forehead. Perifascial areolar tissue with 5- to 10-mm fat thickness was harvested from the inguinal region. The fat-containing PAT was grafted to the defect contacting the vascularized wound bed. Patients were followed up in terms of their clinical symptoms and postoperative magnetic resonance imaging findings. Four patients were treated using fat-containing PAT after tumor resection. One patient was treated for a posttraumatic forehead depression deformity. The fat-containing PAT included 5- to 9-mm fat thickness in all cases. The mean size of grafted PAT was 65.6 cm (28-140 cm). The mean follow-up period was 18.6 months (12-31 months). There was no notable complication. There was no donor site morbidity. We can harvest PAT with fat easily and obtain the sufficient volume to treat the defect. It also could be used with other reconstructive method, such as a free flap or a regional flap to fill the left dead space. Therefore, fat-containing PAT could be additional options to reconstruction of skull base defect.
authors.affiliation: From the *Department of Plastic and Reconstructive Surgery, Chosun University College of Medicine, Gwangju; †Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, and ‡Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Woo Young
authors.initials: WY
authors.lastname: Choi
authors.forename: Ki Wook
authors.initials: KW
authors.lastname: Sung
authors.forename: Young Seok
authors.initials: YS
authors.lastname: Kim
authors.forename: Jong Won
authors.initials: JW
authors.lastname: Hong
authors.forename: Tai Suk
authors.initials: TS
authors.lastname: Roh
authors.forename: Dae Hyun
authors.initials: DH
authors.lastname: Lew
authors.forename: Jong Hee
authors.initials: JH
authors.lastname: Chang
authors.forename: Kyu Sung
authors.initials: KS
authors.lastname: Lee
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D002817:Chordoma / Q000601:surgery*; D005205:Fascia / Q000637:transplantation*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D019291:Skull Base / Q000293:injuries / Q000601:surgery*; D019292:Skull Base Neoplasms / Q000601:surgery*; D016896:Treatment Outcome