title: [Pneumococcal disease in adults: Risk levels and vaccine recommendations].
abstract: There are currently two anti-pneumococcal vaccines available for use in adults: the classical 23-valent polysaccharide pneumococcal vaccine (PPV23) and the new 13-valent pneumococcal conjugate vaccine (PCV13). The main advantage of the PCV13 is the potentially better immunogenicity, with its major disadvantages being the higher cost and the lower serotype-coverage than the PPV23. The currently available scientific evidence supports the following basic recommendations: (i)among adults with greatest risk (basically asplenia and immunocompromised), a dual vaccination (PCV13+PPV23) is recommended; (ii)among adults with increased risk (basically persons >65years-old and patients 15-64years with chronic pulmonary or heart disease, diabetes and/or alcoholism), a single vaccination with PPV23 is recommended (single dose in primo-vaccinated >65years; re-vaccination at 5-10years in those primo-vaccinated <65years-old); and (iii) in the rest of adults (risk normal/low) vaccination is not recommended.
authors.affiliation: Direcció d'Atenció Primària Camp de Tarragona, Institut Català de la Salut, Tarragona, España.
authors.forename: Angel
authors.initials: A
authors.lastname: Vila-Córcoles
authors.affiliation: Direcció d'Atenció Primària Camp de Tarragona, Institut Català de la Salut, Tarragona, España. Electronic address: oochoa.tarte.ics@gencat.cat.
authors.forename: Olga
authors.initials: O
authors.lastname: Ochoa-Gondar
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000517:prevention & control*; D022242:Pneumococcal Vaccines; D017410:Practice Guidelines as Topic; D018570:Risk Assessment; D055815:Young Adult
chemical_list: C538862:13-valent pneumococcal vaccine; C414006:23-valent pneumococcal capsular polysaccharide vaccine; D022242:Pneumococcal Vaccines
keywords: Adultos; Adults; Anti-pneumococcal vaccine; Enfermedad neumocócica; Pneumococcal disease; Recomendaciones; Recommendations; Vacunación antineumocócica