title: High-flow humidified nasal oxygenation vs. standard face mask oxygenation.
abstract: Ten healthy volunteers received oxygen for 1 min, 2 min and 3 min at 10 l.min-1via a face mask, or humidified oxygen at 60 l.min-1via nasal prongs (OptiflowTM) with the mouth closed and with the mouth open. The mean (SD) end-tidal oxygen partial pressure after 3 min face mask and Optiflow oxygenation, with mouth closed and open, were: 88.5 (6.2) kPa; 85.6 (6.4) kPa and 48.7 (26.4) kPa, respectively, p = 0.001. The equivalent mean (SD) transcutaneous oxygen partial pressures were: 34.6 (5.4) kPa; 36.4 (6.5) kPa and 25.5 (15.7) kPa, respectively, p = 0.03. High-flow humidified nasal oxygenation for 3 min with the mouth closed was as effective as 3 min face mask oxygenation.
authors.affiliation: Anaesthetic Department, Royal Perth Hospital, Perth, Western Australia, Australia. aranipillai@doctors.org.uk.
authors.forename: A
authors.initials: A
authors.lastname: Pillai
authors.affiliation: Anaesthetic Department, University Hospitals of Coventry and Warwickshire NHS Trust, Coventry, UK.
authors.forename: V
authors.initials: V
authors.lastname: Daga
authors.affiliation: Anaesthetic Department, Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: J
authors.initials: J
authors.lastname: Lewis
authors.affiliation: Anaesthetic Department, Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: M
authors.initials: M
authors.lastname: Mahmoud
authors.affiliation: Anaesthetic Department, University Hospitals of Leicester NHS Trust, Leicester, UK.
authors.forename: M
authors.initials: M
authors.lastname: Mushambi
authors.affiliation: Anaesthetic Department, Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: D
authors.initials: D
authors.lastname: Bogod
mesh_terms: D000293:Adolescent; D000328:Adult; D001785:Blood Gas Monitoring, Transcutaneous; D000072601:Cannula; D018592:Cross-Over Studies; D006801:Humans; D006813:Humidity; D008397:Masks; D010102:Oxygen Inhalation Therapy / Q000295:instrumentation / Q000379:methods*; D010313:Partial Pressure; D055815:Young Adult
keywords: high-flow humidified nasal oxygen; pre-oxygenation; transcutaneous oxygen monitoring