title: Sedentary behavior and residual-specific mortality.
abstract: Background:The purpose of this study was to examine the association of accelerometer-assessed sedentary behavior and residual-specific mortality.Methods:Data from the 2003-2006 National Health and Nutrition Examination Survey (NHANES) were used (N = 5536), with follow-up through 2011. Sedentary behavior was objectively measured over 7 days via accelerometry.Results:When expressing sedentary behavior as a 60 min/day increase, the hazard ratio across the models ranged from 1.07-1.40 (P < 0.05). There was evidence of an interaction effect between sedentary behavior and total physical activity on residual-specific mortality (Hazard ratiointeraction[HR] = 0.9989; 95% CI: 0.9982-0.9997; P = 0.008).Conclusion:Sedentary behavior was independently associated with residual-specific mortality. However, there was evidence to suggest that residual-specific mortality risk was a function of sedentary behavior and total physical activity. These findings highlight the need for future work to not only examine the association between sedentary behavior and health independent of total physical activity, but evaluate whether there is a joint effect of these two parameters on health.
authors.affiliation: Jackson Heart Study Vanguard Center of Oxford, Center for Health Behavior Research, Physical Activity Epidemiology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS 38677, USA.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Loprinzi
authors.affiliation: Center for Health Behavior Research, Physical Activity Epidemiology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS 38677, USA.
authors.forename: Meghan K
authors.initials: MK
authors.lastname: Edwards
authors.affiliation: Center for Health Behavior Research, Physical Activity Epidemiology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS 38677, USA.
authors.forename: Eveleen
authors.initials: E
authors.lastname: Sng
authors.affiliation: Mississippi Baptist Health Systems - Baptist Outpatient Cardiac Rehabilitation, Center for Health Behavior Research, Physical Activity Epidemiology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS 38677, USA.
authors.forename: Ovuokerie
authors.initials: O
authors.lastname: Addoh
keywords: Accelerometry; Epidemiology; Physical activity; Survival