title: Critical care provision after colorectal cancer surgery.
abstract: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of organ support. The aim of this study was to identify pre-operative risk factors that increased the likelihood of this occurring.
  
  
  
  This is a retrospective observational study of all 6441 patients who underwent colorectal cancer surgery within the West of Scotland Region between 2005 and 2011. Logistic regression was employed to determine factors associated with receiving postoperative organ support.
  
  
  
  A total of 610 (9 %) patients received organ support. Multivariate analysis identified age ≥65, male gender, emergency surgery, social deprivation, heart failure and type II diabetes as being independently associated with organ support postoperatively. After adjusting for demographic and clinical factors, patients with metastatic disease appeared less likely to receive organ support (p = 0.012).
  
  
  
  Nearly one in ten patients undergoing CRC surgery receive organ support in the post operative period. We identified several risk factors which increase the likelihood of receiving organ support post operatively. This is relevant when consenting patients about the risks of CRC surgery.
authors.affiliation: Undergraduate Medical School, School of Medicine, University of Glasgow, Glasgow, UK.
authors.forename: C D
authors.initials: CD
authors.lastname: Dale
authors.affiliation: West of Scotland Cancer Surveillance Unit, Public Health Research Group, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
authors.forename: P
authors.initials: P
authors.lastname: McLoone
authors.affiliation: West of Scotland Cancer Surveillance Unit, Public Health Research Group, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
authors.forename: B
authors.initials: B
authors.lastname: Sloan
authors.affiliation: Anaesthesia, Critical Care and Pain Medicine, School of Medicine, Glasgow Royal Infirmary, Glasgow, Scotland, UK.
authors.forename: J
authors.initials: J
authors.lastname: Kinsella
authors.affiliation: West of Scotland Cancer Surveillance Unit, Public Health Research Group, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
authors.forename: D
authors.initials: D
authors.lastname: Morrison
authors.affiliation: Anaesthesia, Critical Care and Pain Medicine, School of Medicine, Glasgow Royal Infirmary, Glasgow, Scotland, UK. kpuxty@nhs.net.
authors.forename: K
authors.initials: K
authors.lastname: Puxty
authors.affiliation: Anaesthesia, Critical Care and Pain Medicine, School of Medicine, Glasgow Royal Infirmary, Glasgow, Scotland, UK.
authors.forename: T
authors.initials: T
authors.lastname: Quasim
mesh_terms: D000367:Age Factors; D000368:Aged; D015179:Colorectal Neoplasms / Q000601:surgery*; D003422:Critical Care / Q000379:methods*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009362:Neoplasm Metastasis; D011182:Postoperative Care / Q000379:methods*; D011184:Postoperative Period; D012189:Retrospective Studies; D012307:Risk Factors; D012606:Scotland; D012737:Sex Factors
keywords: Colorectal cancer; ICU; Organ support; Surgery