title: Enamel Matrix Derivative Proteins in Combination with a Flapless Approach for Periodontal Regeneration of Intrabony Defects: A 2-Year Prospective Case Series.
abstract: The present case series evaluated the potential benefits of a flapless approach in the regenerative treatment of residual deep intrabony defects. In each of 11 patients, one periodontal defect with an intrabony component of ≥ 3 mm was treated regeneratively using enamel matrix derivative combined with a closed surgical technique. Clinical and radiographic parameters were recorded at baseline and at 12 and 24 months postoperatively. All defects experienced favorable clinical and radiographic outcomes at the 24-month follow-up. When considering only sites located in the anterior region, all experienced complete pocket closure.
authors.forename: Mario
authors.initials: M
authors.lastname: Aimetti
authors.forename: Francesco
authors.initials: F
authors.lastname: Ferrarotti
authors.forename: Giulia
authors.initials: G
authors.lastname: Mariani
authors.forename: Adriano
authors.initials: A
authors.lastname: Fratini
authors.forename: Marta
authors.initials: M
authors.lastname: Giraudi
authors.forename: Federica
authors.initials: F
authors.lastname: Romano
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000188:drug therapy* / Q000601:surgery*; D055113:Chronic Periodontitis / Q000188:drug therapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D003746:Dental Enamel Proteins / Q000494:pharmacology*; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins