title: Ruthenium-Catalyzed C-H Arylation of Diverse Aryl Carboxylic Acids with Aryl and Heteroaryl Halides.
abstract: Ruthenium ligated to tricyclohexylphosphine or di-tert-butylbipyridine catalyzes the arylation of carboxylic acids with diverse aryl halides (iodide, bromide, and triflate; aryl and heteroaryl). In addition, arylations with 2-iodophenol formed benzochromenones, carboxylate was shown to be a stronger donor than an amide, and the arylation of a pyridine carboxylate was demonstrated. Stoichiometric studies demonstrated that the added ligand is required for reaction with the electrophile but not the C-H bond.
authors.affiliation: University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Liangbin
authors.initials: L
authors.lastname: Huang
authors.affiliation: University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Weix
mesh_terms: D002264:Carboxylic Acids / Q000138:chemical synthesis*; D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D006846:Hydrocarbons, Halogenated; D011725:Pyridines; D012428:Ruthenium