title: Daily Use of a Facial Broad Spectrum Sunscreen Over One-Year Significantly Improves Clinical Evaluation of Photoaging.
abstract: BACKGROUND
  Sunscreens are known to protect from sun damage; however, their effects on the reversal of photodamage have been minimally investigated.
  
  
  OBJECTIVE
  The aim of the prospective study was to evaluate the efficacy of a facial sun protection factor (SPF) 30 formulation for the improvement of photodamage during a 1-year use.
  
  
  METHODS
  Thirty-two subjects applied a broad spectrum photostable sunscreen (SPF 30) for 52 weeks to the entire face. Assessments were conducted through dermatologist evaluations and subjects' self-assessment at baseline and then at Weeks 12, 24, 36, and 52.
  
  
  RESULTS
  Clinical evaluations showed that all photoaging parameters improved significantly from baseline as early as Week 12 and the amelioration continued until Week 52. Skin texture, clarity, and mottled and discrete pigmentation were the most improved parameters by the end of the study (40% to 52% improvement from baseline), with 100% of subjects showing improvement in skin clarity and texture.
  
  
  CONCLUSIONS
  The daily use of a facial broad-spectrum photostable sunscreen may visibly reverse the signs of existing photodamage, in addition to preventing additional sun damage.
authors.affiliation: *Skin Research Center, Johnson & Johnson Consumer Companies, Inc., Skillman, New Jersey; †Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, New York; ‡KGL Skin Study Center, Broomall, Pennsylvania; §Pagnoni Consulting LLC.
authors.forename: Manpreet
authors.initials: M
authors.lastname: Randhawa
authors.forename: Steven
authors.initials: S
authors.lastname: Wang
authors.forename: James J
authors.initials: JJ
authors.lastname: Leyden
authors.forename: Gabriela O
authors.initials: GO
authors.lastname: Cula
authors.forename: Alessandra
authors.initials: A
authors.lastname: Pagnoni
authors.forename: Michael D
authors.initials: MD
authors.lastname: Southall
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D015595:Skin Aging / Q000187:drug effects* / Q000528:radiation effects*; D013472:Sunlight / Q000009:adverse effects*; D013473:Sunscreening Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D013473:Sunscreening Agents