title: Alopecia universalis as a side effect of pegylated interferon α-ribavirin combination therapy for hepatitis C: a rare case report.
abstract: Pegylated interferon α and ribavirin therapy is associated with increased incidence of various systemic and cutaneous side effects. Among the side effects of this therapy, alopecia universalis is a rarely reported side effect which causes significant cosmetic concern to the patient. We report a rare case of alopecia universalis which developed eight weeks after discontinuation of this antiviral combination therapy. This gains importance because it is essential to sensitize the treating gastroenterologist and the dermatologist regarding this rare side effect.
authors.affiliation: a Department of Dermatology , Pt. B.D.Sharma, PGIMS , Rohtak , India.
authors.forename: Poonam
authors.initials: P
authors.lastname: Verma
authors.affiliation: a Department of Dermatology , Pt. B.D.Sharma, PGIMS , Rohtak , India.
authors.forename: Surabhi
authors.initials: S
authors.lastname: Dayal
authors.affiliation: a Department of Dermatology , Pt. B.D.Sharma, PGIMS , Rohtak , India.
authors.forename: V K
authors.initials: VK
authors.lastname: Jain
authors.affiliation: a Department of Dermatology , Pt. B.D.Sharma, PGIMS , Rohtak , India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Amrani
mesh_terms: D000328:Adult; D000505:Alopecia / Q000139:chemically induced*; D000998:Antiviral Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004359:Drug Therapy, Combination / Q000009:adverse effects; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000009:adverse effects*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000009:adverse effects; D012254:Ribavirin / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; D012254:Ribavirin; C417083:peginterferon alfa-2b
keywords: Alopecia universalis; Interferon; Ribavirin