title: Good weight loss responders and poor weight loss responders after Roux-en-Y gastric bypass: clinical and nutritional profiles.
abstract: BACKGROUND
  Bariatric surgery is one of the main treatments for severity obesity, but weight regain after surgery is an important issue.
  
  
  OBJECTIVE
  To compare the clinical and nutritional profiles of good and poor weight loss responders in the late postoperative period after bariatric surgery.
  
  
  METHODS
  A cross-sectional study with patients undergoing Roux-en-Y gastric bypass in a University Hospital. Patients were divided into good weight loss responders (GWLR) and poor weight loss responders (PWLR) defined as ≥ 50% or < 50% excess weight loss (EWL), respectively, at least 2 years post-surgery.
  
  
  RESULTS
  The sample included 204 individuals (87.7% women; mean age 50.15 ± 11.1 years; mean time after surgery 67.38 ± 30.76 months). Two years post-surgery, 71.1% were considered GWLR and 28.9% PWLR (mean EWL 72.33% ± 13.86%, and 35.06% ± 12.10%, respectively; p = 0.000). Weight regain was < 10% for 36.3% of patients, 10.1-20% for 36.3%, and > 20% for 21.3%, compared with the lowest post-surgery weight. Among PWLR, 49.0% regained > 20% of the lowest post-surgery weight. GWLR lost most weight at all time points analyzed (p < 0.05). GWLR presented improvement or remission of diabetes, dyslipidemia and hypertension more frequently compared to PWLR (p < 0.05). Eating patterns was similar between GWLR and PWLR (p > 0.05, study's power 100%). Quality of life improved in 79.5% of the total study sample, with greater improvements in the GWLR (p < 0.05).
  
  
  CONCLUSIONS
  Greater weight loss correlated with improved remission in comorbidities and better quality of life.
authors.affiliation: Internal Medicine and Health Sciences, Hospital de Clínicas. Federal University of Parana (UFPR). Curitiba. Parana. gisele.nutri.farias@gmail.com.
authors.forename: Gisele
authors.initials: G
authors.lastname: Farias
authors.forename: Rubia D
authors.initials: RD
authors.lastname: Thieme
authors.forename: Laila M
authors.initials: LM
authors.lastname: Teixeira
authors.forename: Maria Emilia V D
authors.initials: ME
authors.lastname: Heyde
authors.forename: Solange C
authors.initials: SC
authors.lastname: Bettini
authors.forename: Rosana B
authors.initials: RB
authors.lastname: Radominski
mesh_terms: D000328:Adult; D000368:Aged; D050110:Bariatric Surgery; D003430:Cross-Sectional Studies; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D009767:Obesity, Morbid / Q000601:surgery; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome; D015431:Weight Loss; D055815:Young Adult
keywords: Gastric bypass.  Long-term  post-surgery. Weight  loss. Nutrition.  Co-morbidity.