title: Antibiotic Resistance in Pediatric Urinary Tract Infections.
abstract: Urinary tract infections (UTIs) are a common problem in pediatric patients. Resistance to common antibiotic agents appears to be increasing over time, although resistance rates may vary based on geographic region or country. Prior antibiotic exposure is a pertinent risk factor for acquiring resistant organisms during a first UTI and recurrent UTI. Judicious prescribing of antibiotics for common pediatric conditions is needed to prevent additional resistance from occurring. Complex pediatric patients with histories of hospitalizations, prior antibiotic exposure, and recurrent UTIs are also at high risk for acquiring UTIs due to extended spectrum beta-lactamase-producing organisms. Data regarding the impact of in vitro antibiotic susceptibility testing interpretation on UTI treatment outcomes is lacking.
authors.affiliation: Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University School of Pharmacy, Smith Building, Room 435, 410 N 12th Street, P.O. Box 980533, Richmond, VA, 23298, USA. jsstultz@vcu.edu.
authors.forename: Jeremy S
authors.initials: JS
authors.lastname: Stultz
authors.affiliation: Department of Pathology, Virginia Commonwealth University Health System, Richmond, VA, 23298, USA.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Doern
authors.affiliation: Department of Pediatrics, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, 23298, USA.
authors.forename: Emily
authors.initials: E
authors.lastname: Godbout
keywords: Extended spectrum beta-lactamases; Microbial sensitivity tests; Pediatric; Urinary tract infections