title: para-Selective Alkylation of Benzamides and Aromatic Ketones by Cooperative Nickel/Aluminum Catalysis.
abstract: We report a method that ensures the selective alkylation of benzamides and aromatic ketones at the para-position via cooperative nickel/aluminum catalysis. Using a bulky catalyst/cocatalyst system allows reactions between benzamides and alkenes to afford the corresponding para-alkylated products. The origin of the high para-selectivity has also been investigated by density functional theory calculations.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University , Kyoto 615-8510, Japan.
authors.forename: Shogo
authors.initials: S
authors.lastname: Okumura
authors.affiliation: Fukui Institute for Fundamental Chemistry, Kyoto University , Sakyo-ku, Kyoto 606-8103, Japan.
authors.forename: Shuwei
authors.initials: S
authors.lastname: Tang
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University , Kyoto 615-8510, Japan.
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Saito
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University , Kyoto 615-8510, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Semba
authors.affiliation: Fukui Institute for Fundamental Chemistry, Kyoto University , Sakyo-ku, Kyoto 606-8103, Japan.
authors.forename: Shigeyoshi
authors.initials: S
authors.lastname: Sakaki
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University , Kyoto 615-8510, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nakao