title: Coronary artery disease prevalence and outcome in patients hospitalized with acute heart failure: an observational report from seven Middle Eastern countries.
abstract: OBJECTIVE
  The purpose of this study was to report prevalence, clinical characteristics, precipitating factors, management and outcome of patients with coronary artery disease (CAD) among patients hospitalized with heart failure (HF) in seven Middle Eastern countries and compare them to non-CAD patients.
  
  
  METHODS
  Data were derived from Gulf CARE (Gulf aCute heArt failuRe rEgistry), a prospective multicenter study of 5005 consecutive patients hospitalized with acute HF during February-November 2012 in 7 Middle Eastern countries.
  
  
  RESULTS
  The prevalence of CAD among Acute Heart Failure (AHF) patients was 60.2% and varied significantly among the 7 countries (Qatar 65.7%, UAE 66.6%, Kuwait 68.0%, Oman 65.9%, Saudi Arabia 62.5%, Bahrain 52.7% and Yemen 49.1%) with lower values in the lower income countries. CAD patients were older and more likely to have diabetes, hypertension, dyslipidemia and chronic kidney disease. Moreover, CAD patients were more likely to have history of cerebrovascular and peripheral vascular disease when compared to non-CAD patients. In-hospital mortality rates were comparable although CAD patients had more frequent re-hospitalization and worse long-term outcome. However, CAD was not an independent predictor of poor outcome.
  
  
  CONCLUSIONS
  The prevalence of CAD amongst patients with HF in the Middle East is variable and may be related to healthcare sources. Regional and national studies are needed for assessing further the impact of various etiologies of HF and for developing appropriate strategies to combat this global concern.
authors.affiliation: a Department of Cardiology , Al-khor Hospital, Hamad Medical Corporation , Doha , Qatar.
authors.forename: Amar M
authors.initials: AM
authors.lastname: Salam
authors.affiliation: b Department of Cardiology , Royal Hospital , Muscat , Oman.
authors.forename: Kadhim
authors.initials: K
authors.lastname: Sulaiman
authors.affiliation: c Department of Pharmacology & Clinical Pharmacy , Sultan Qaboos University , Muscat , Oman.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Al-Zakwani
authors.affiliation: d College of Medicine , Mohammed Bin Rashid Medical University , Dubai , United Arab Emirates.
authors.forename: Alawi
authors.initials: A
authors.lastname: Alsheikh-Ali
authors.affiliation: e Sabah Alahmad Cardiac Center , Kuwait , Kuwait.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Aljaraallah
authors.affiliation: f Department of Cardiology and Cardiovascular Surgery , King Saud University , Riyadh , Saudi Arabia.
authors.forename: Husam
authors.initials: H
authors.lastname: Al Faleh
authors.affiliation: g Department of Cardiology , Prince Salman Hospital , Riyadh , Saudi Arabia.
authors.forename: Abdelfatah
authors.initials: A
authors.lastname: Elasfar
authors.affiliation: b Department of Cardiology , Royal Hospital , Muscat , Oman.
authors.forename: Prasanth
authors.initials: P
authors.lastname: Panduranga
authors.affiliation: a Department of Cardiology , Al-khor Hospital, Hamad Medical Corporation , Doha , Qatar.
authors.forename: Rajvir
authors.initials: R
authors.lastname: Singh
authors.affiliation: h Department of Genetic Medicine and Department of Medicine , Weill Cornell Medical College in Qatar , Doha , Qatar.
authors.forename: Charbel
authors.initials: C
authors.lastname: Abi Khalil
authors.affiliation: i Department of Adult Cardiology and Cardiovascular Surgery , Heart Hospital, Hamad Medical Corporation , Doha , Qatar.
authors.forename: Jassim
authors.initials: J
authors.lastname: Al Suwaidi
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002317:Cardiovascular Agents / Q000627:therapeutic use; D015897:Comorbidity; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008877:Middle East / Q000453:epidemiology; D010359:Patient Readmission; D015995:Prevalence; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors
chemical_list: D002317:Cardiovascular Agents
keywords: Coronary artery disease; Middle East; heart failure; morbidity; mortality