title: Reproductive dysfunctions in viral hepatitis.
abstract: The viral hepatitis abnormalities in the female reproductive system are due to hepatic and extrahepatic damage. On the background of HBV- and HCV-infections, menstrual disorders prevail in the structure of reproductive system pathology; disorders of reproductive function in the form of pregnancy loss and infertility are detected in each second case. Depression of T-cell immunity in the immune status is observed in the patients with intact reproductive function. When miscarriage was in past medical history then divergent changes subpopulations of lymphocytes are found. When patients have infertility, signify depression of T-cell immunity is observed with a decrease in total T-cells, T-helper cells and active lymphocytes.
authors.affiliation: a Scientific Center of Obstetric, Gynecology and Perinatology , Almaty , Kazakhstan.
authors.forename: A M
authors.initials: AM
authors.lastname: Kurmanova
authors.affiliation: b Kazakh National Medical University , Almaty , Kazakhstan and.
authors.forename: G M
authors.initials: GM
authors.lastname: Kurmanova
authors.affiliation: c Reproduction Medicine Institute , Almaty , Kazakhstan.
authors.forename: V N
authors.initials: VN
authors.lastname: Lokshin
mesh_terms: D000022:Abortion, Spontaneous / Q000097:blood* / Q000209:etiology; D000328:Adult; D005260:Female; D006525:Hepatitis, Viral, Human / Q000097:blood* / Q000150:complications; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000209:etiology; D018655:Lymphocyte Count
keywords: Immunity; reproductive dysfunction; viral hepatitis