title: The Chronic Encephalopathy of Parry Romberg Syndrome and EnCoupe De Sabrewith a 31-Year-History in a West Indian Woman: Clinical, Immunologic and Neuroimaging Abnormalities.
abstract: We describe a case of Parry Romberg syndrome/en coupe de sabrein a woman whose disease started as seizures at age 8 but was diagnosed at the age 39. During these 31 years she got married, completed a first degree at university, had two successful pregnancies and has been gainfully employed. The features of generalized tonic-clonic seizures, autoimmune abnormalities, ocular abnormalities, morpheaen coup de sabreand brain imaging abnormalities were present. Areas of parietal lobe cerebral calcification were encountered on the computed tomographic scan and bilateral periventricular white matter changes on the magnetic resonance imaging with frontal, temporal and parietal lobe brain atrophy ipsilateral to the facial hemiatrophy. Clinical, immunologic and neuroradiological abnormalities are discussed. In some cases, this illness can run a benign and stable course.
authors.affiliation: Neurology Unit, San Fernando Teaching Hospital.
authors.forename: Karan
authors.initials: K
authors.lastname: Seegobin
authors.affiliation: Neurology Unit, San Fernando Teaching Hospital; University of the West Indies.
authors.forename: Kamille
authors.initials: K
authors.lastname: Abdool
authors.affiliation: Neurology Unit, San Fernando Teaching Hospital; University of the West Indies.
authors.forename: Kanterpersad
authors.initials: K
authors.lastname: Ramcharan
authors.affiliation: University of the West Indies; Rheumatology Unit, San Fernando Teaching Hospital.
authors.forename: Haramnauth
authors.initials: H
authors.lastname: Dyaanand
authors.affiliation: University of the West Indies; Radiology Department, University of the West Indies, Trinidad and Tobago.
authors.forename: Fidel
authors.initials: F
authors.lastname: Rampersad
keywords: Encephalopathy; Neuroradiology; Parry Romberg Syndrome; Rheumatology; West Indies