title: A negative view of menopause: does the type of symptom matter?
abstract: OBJECTIVE
  To assess the association between the type of symptom and women's self-reported view of menopause.
  
  
  METHODS
  The study was conducted at Mayo Clinic, Rochester MN, between January 2006 and October 2014. Women aged 40-64 were included. Data from 1420 women were analyzed in a cross-sectional design. The Menopause Health Questionnaire was used for symptom assessment. Odds ratios (ORs) and population attributable risk (PAR) (OR × percent frequency) were calculated for each symptom. Logistic regression analyses were performed with the view of menopause as the dependent variable.
  
  
  RESULTS
  Anxiety (2.34), depressed mood (2.24), irritability (2.22), vaginal itching (2.27), crying spells (2.1) and breast tenderness (2.08) were associated with highest odds of having a negative view of menopause. Highest PAR (population impact) symptoms were anxiety (22.27), weight gain (20.66), fatigue (20.28) and irritability (19.41). Hot flushes and night sweats, although common, were not associated with a negative view of menopause (OR 1.3 and 1.16; PAR 3.85 and 4.42, respectively).
  
  
  CONCLUSIONS
  Mood symptoms, vaginal itching, weight gain, breast tenderness and fatigue, although less common than hot flushes, were noted to have greater association with a negative view of menopause. Specifically addressing these symptoms during menopausal consultation may improve patient satisfaction and outcomes.
authors.affiliation: a Women's Health Clinic, Division of General Internal Medicine , Mayo Clinic , Rochester , MN , USA.
authors.forename: R
authors.initials: R
authors.lastname: Sood
authors.affiliation: a Women's Health Clinic, Division of General Internal Medicine , Mayo Clinic , Rochester , MN , USA.
authors.forename: C
authors.initials: C
authors.lastname: Kuhle
authors.affiliation: a Women's Health Clinic, Division of General Internal Medicine , Mayo Clinic , Rochester , MN , USA.
authors.forename: E
authors.initials: E
authors.lastname: Kapoor
authors.affiliation: a Women's Health Clinic, Division of General Internal Medicine , Mayo Clinic , Rochester , MN , USA.
authors.forename: J
authors.initials: J
authors.lastname: Rullo
authors.affiliation: a Women's Health Clinic, Division of General Internal Medicine , Mayo Clinic , Rochester , MN , USA.
authors.forename: J
authors.initials: J
authors.lastname: Thielen
authors.affiliation: a Women's Health Clinic, Division of General Internal Medicine , Mayo Clinic , Rochester , MN , USA.
authors.forename: K
authors.initials: K
authors.lastname: Frohmader
authors.affiliation: b Biomedical Statistics and Informatics, Division of Health Sciences Research , Mayo Clinic , Rochester , MN , USA.
authors.forename: K
authors.initials: K
authors.lastname: Mara
authors.affiliation: b Biomedical Statistics and Informatics, Division of Health Sciences Research , Mayo Clinic , Rochester , MN , USA.
authors.forename: D
authors.initials: D
authors.lastname: Schroeder
authors.affiliation: a Women's Health Clinic, Division of General Internal Medicine , Mayo Clinic , Rochester , MN , USA.
authors.forename: S
authors.initials: S
authors.lastname: Faubion
mesh_terms: D000328:Adult; D000339:Affect; D001007:Anxiety; D001290:Attitude; D003430:Cross-Sectional Studies; D003863:Depression / Q000523:psychology; D005221:Fatigue / Q000523:psychology; D005260:Female; D019584:Hot Flashes; D006801:Humans; D007508:Irritable Mood; D059373:Mastodynia / Q000523:psychology; D008593:Menopause / Q000502:physiology* / Q000523:psychology*; D008875:Middle Aged; D011537:Pruritus / Q000523:psychology; D011795:Surveys and Questionnaires; D013546:Sweating; D014623:Vaginal Diseases / Q000523:psychology; D015430:Weight Gain
keywords: Hot flush; menopausal symptoms; menopause; symptom bother; vasomotor symptoms; view of menopause