title: Pulmonary Cryptococcoma Masquerading as Lung Cancer.
abstract: We report a case of pulmonary cryptococcoma, in an adult with recently detected diabetes, mimicking as lung cancer. A 45-year-old gentleman with past history of pulmonary tuberculosis presented with fever, cough with expectoration, pleuritic chest pain and hemoptysis. Chest radiograph and computed tomography revealed right lower lobe mass which significantly enhanced on contrast administration. Ultrasound guided biopsy was done which on histopathological examination showed non-necrotizing granulomas with narrow-based budding yeast cells suggestive of cryptococcosis. Detailed work-up for dissemination of infection was negative. A dramatic response to anti-fungal treatment was observed and the patient is doing fine on follow-up.
authors.affiliation: Department of Medicine.
authors.forename: Satyajit
authors.initials: S
authors.lastname: Pawar
authors.affiliation: Department of Medicine.
authors.forename: Vanishri
authors.initials: V
authors.lastname: Ganakumar
authors.affiliation: Department of Medicine.
authors.forename: Saket
authors.initials: S
authors.lastname: Jha
authors.forename: R
authors.initials: R
authors.lastname: Ragesh
authors.affiliation: Department of Medicine.
authors.forename: Animesh
authors.initials: A
authors.lastname: Ray
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi.
authors.forename: Aanchal
authors.initials: A
authors.lastname: Kakkar
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi.
authors.forename: M C
authors.initials: MC
authors.lastname: Sharma
authors.affiliation: Department of Medicine.
authors.forename: S K
authors.initials: SK
authors.lastname: Sharma
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D002637:Chest Pain / Q000000981:diagnostic imaging*; D003371:Cough / Q000209:etiology; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D015725:Fluconazole / Q000627:therapeutic use; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole