title: Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
abstract: The goal of biomarker research is to identify clinically valid markers. Despite decades of research there has been disappointingly few molecules or techniques that are in use today. The "1st International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer: Innovation and Implementation", was held June 16th and 17th 2016, at the Knowledge Center of the St. Olavs Hospital in Trondheim, Norway, under the auspices of the Norwegian University of Science and Technology (NTNU) and the HUNT biobank and research center. The Symposium attracted approximately 100 attendees and invited speakers from 12 countries and 4 continents. In this Symposium original research and overviews on diagnostic, predictive and prognostic cancer biomarkers in serum, plasma, urine, pleural fluid and tumor, circulating tumor cells and bioinformatics as well as how to implement biomarkers in clinical trials were presented. Senior researchers and young investigators presented, reviewed and vividly discussed important new developments in the field of clinical biomarkers of cancer, with the goal of accelerating biomarker research and implementation. The excerpts of this symposium aim to give a cutting-edge overview and insight on some highly important aspects of clinical cancer biomarkers to-date to connect molecular innovation with clinical implementation to eventually improve patient care.
authors.affiliation: Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, USA.
authors.forename: Ana I
authors.initials: AI
authors.lastname: Robles
authors.affiliation: Department of Community Medicine, UiT The Artic University of Norway, Tromsø, Norway.
authors.forename: Karina Standahl
authors.initials: KS
authors.lastname: Olsen
authors.affiliation: Department of Pathology and Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, USA.
authors.forename: Dana W T
authors.initials: DW
authors.lastname: Tsui
authors.affiliation: Department of Medical Oncology, School of MedicineUniversity of Crete, Heraklion, Greece.
authors.forename: Vassilis
authors.initials: V
authors.lastname: Georgoulias
authors.affiliation: National Centre for Asbestos Related Disease, University of Western Australia, Perth, Australia.
authors.forename: Jenette
authors.initials: J
authors.lastname: Creaney
authors.affiliation: Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Katalin
authors.initials: K
authors.lastname: Dobra
authors.affiliation: Department of Clinical Medicine, Institute of Pathology, Aalborg University Hospital, Aalborg University, Aalborg, Denmark.
authors.forename: Mogens
authors.initials: M
authors.lastname: Vyberg
authors.affiliation: Department of Immunology and Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Nagahiro
authors.initials: N
authors.lastname: Minato
authors.affiliation: Department of Pathology, Johns Hopkins University, Baltimore, USA.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Anders
authors.affiliation: Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway.
authors.forename: Anne-Lise
authors.initials: AL
authors.lastname: Børresen-Dale
authors.affiliation: Department of Molecular Cell Biology & Toxicology, Cancer Center School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China.
authors.forename: Jianwei
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Department of Computer and Information Science, NTNU, Trondheim, Norway.
authors.forename: Pål
authors.initials: P
authors.lastname: Sætrom
authors.affiliation: Molecular Histology Bioneer A/S, Hørsholm, Denmark.
authors.forename: Boye Schnack
authors.initials: BS
authors.lastname: Nielsen
authors.affiliation: Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
authors.forename: Michaela B
authors.initials: MB
authors.lastname: Kirschner
authors.affiliation: Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
authors.forename: Hans E
authors.initials: HE
authors.lastname: Krokan
authors.affiliation: Department of Thoracic/Head and Neck Medical Oncology, MD Anderson, Houston, USA.
authors.forename: Vassiliki
authors.initials: V
authors.lastname: Papadimitrakopoulou
authors.affiliation: Department of Computer Science, University of Crete, Heraklion, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Tsamardinos
authors.affiliation: Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. oluf.roe@ntnu.no.|Cancer Clinic, Department of SurgeryLevanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway. oluf.roe@ntnu.no.|Department of Clinical Medicine, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark. oluf.roe@ntnu.no.
authors.forename: Oluf D
authors.initials: OD
authors.lastname: Røe
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood / Q000378:metabolism* / Q000652:urine; D019992:Databases as Topic; D006801:Humans; D038622:Internationality; D009369:Neoplasms / Q000097:blood / Q000473:pathology / Q000652:urine; D009664:Norway; D015203:Reproducibility of Results
chemical_list: D014408:Biomarkers, Tumor
keywords: Bioinformatics; Circulating biomarkers; Circulating tumor cells; DNA repair; Early detection; Early diagnosis