title: Data analytics for continuous renal replacement therapy: historical limitations and recent technology advances.
abstract: OBJECTIVE
  Dialysis is a highly quantitative therapy involving large volumes of both clinical and technical data. While automated data collection has been implemented for chronic dialysis, this has not been done for acute kidney injury patients treated with continuous renal replacement therapy (CRRT).
  
  
  METHODS
  After a brief review of the fundamental aspects of electronic medical records (EMRs), a new tool designed to provide clinicians with individualized CRRT treatment data is analyzed, with emphasis on its quality assurance capabilities.
  
  
  RESULTS
  The first platform addressing the problem of data collection and management with current CRRT machines (Sharesource system; Baxter Healthcare) is described. The system provides connectivity for the Prismaflex CRRT machine and enables both EMR connectivity and therapy analytics with 2 basic components: the connect module and the report module.
  
  
  CONCLUSIONS
  The enormous amount of data in CRRT should be collected and analyzed to enable adequate clinical decisions. Current CRRT technology presents significant limitations with consequent lack of rigorous analysis of technical data and relevant feedback. From a quality assurance perspective, these limitations preclude any systematic assessment of prescription and delivery trends that may be adversely affecting clinical outcomes. A detailed assessment of current practice limitations is provided together with several possible ways to address such limitations by a new technical tool.
authors.affiliation:  School of Biomedical Engineering, Purdue University, West Lafayette, IN - USA.| Department of Mechanical Engineering, University of Washington, Seattle, WA - USA.
authors.forename: William R
authors.initials: WR
authors.lastname: Clark
authors.affiliation:  International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza - Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Garzotto
authors.affiliation:  International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza - Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Neri
authors.affiliation:  International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza - Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Lorenzin
authors.affiliation:  International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza - Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Zaccaria
authors.affiliation:  International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza - Italy.| Department of Nephrology, San Bortolo Hospital, Vicenza - Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Ronco
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy*; D003625:Data Collection / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D017582:Renal Replacement Therapy / Q000295:instrumentation / Q000379:methods*