title: When conventional treatment fails: the role of intravenous immunoglobulin in recurrent pregnancy loss secondary to antiphospholipid syndrome.
abstract: Recurrent pregnancy loss (RPL) is a well-recognized complication of antiphospholipid syndrome (APS). First line therapy consists of low dose aspirin and heparin. Despite conventional therapy some women fail to achieve a successful pregnancy outcome. We describe the case of a patient who had two live births following intravenous immunoglobulin therapy despite previous failure with conventional therapy for RPL in the setting of APS. We will summarize the available literature on intravenous immunoglobulin for this indication.
authors.affiliation: Greenslopes Private Hospital, Newdegate St, Greenslopes, Qld 4102.
authors.forename: Jacklyn
authors.initials: J
authors.lastname: Chay
authors.affiliation: Royal Brisbane and Women's Hospital, Butterfield St, Herston, Qld 4029, Australia.
authors.forename: Karin
authors.initials: K
authors.lastname: Lust
authors.affiliation: Royal Brisbane and Women's Hospital, Butterfield St, Herston, Qld 4029, Australia.
authors.forename: Paul
authors.initials: P
authors.lastname: Kubler
authors.affiliation: Royal Brisbane and Women's Hospital, Butterfield St, Herston, Qld 4029, Australia.
authors.forename: Leonie
authors.initials: L
authors.lastname: Callaway
keywords: IVIG; antiphospholipid syndrome; recurrent pregnancy loss