title: Multidisciplinary Management of Breast Cancer Brain Metastases.
abstract: This review summarizes the most up-to-date approach to the multidisciplinary management of patients with breast cancer brain metastases. A brief overview of the epidemiology and biology of breast cancer brain metastasis is provided. The perspectives of radiation oncology, neurosurgery, and medical oncology-and landmark studies from each discipline-are all discussed. We also offer practical tips to help guide the treating physician, including data on antiseizure medications. Finally, we introduce the concept of a multidisciplinary clinic that combines input from medical and radiation oncology, neurosurgery, and support services, which we developed at the University of North Carolina as a coordinated and optimal approach to the management of patients with this complex disease.
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Zagar
authors.forename: Amanda E D
authors.initials: AE
authors.lastname: Van Swearingen
authors.forename: Orit
authors.initials: O
authors.lastname: Kaidar-Person
authors.forename: Matthew G
authors.initials: MG
authors.lastname: Ewend
authors.forename: Carey K
authors.initials: CK
authors.lastname: Anders
mesh_terms: D000465:Algorithms; D001932:Brain Neoplasms / Q000401:mortality / Q000556:secondary* / Q000628:therapy*; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D003131:Combined Modality Therapy; D019091:Critical Pathways; D003663:Decision Trees; D018450:Disease Progression; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D033183:Interdisciplinary Communication; D010348:Patient Care Team; D011237:Predictive Value of Tests; D016896:Treatment Outcome