title: Characteristics of HPV infection in women at risk in Western Algeria.
abstract: OBJECTIVE
  We aimed to characterize HPV infections and cervical lesions in Western Algeria.
  
  
  METHODS
  A total of 96 cervical samples obtained from women at risk of HPV infection (HIV-1-infected or presenting with a gynecological disease) were analyzed to characterize this infection and search for cytological abnormalities.
  
  
  RESULTS
  A total of 60% of women at risk had an HPV infection. The rate of high-risk HPV (HR-HPV) infection among these women was 84.5% and that of intraepithelial lesions was 29.3%. The frequency of HPV infection was significantly higher among HIV-1-infected patients. An association between the presence of HR-HPV and the polygamy of the partner was observed. An association between cytological abnormalities and the use of oral contraceptives was observed among HIV-1-infected women.
  
  
  CONCLUSIONS
  Given the high frequency of HPV infection in this at risk population, close monitoring and regular gynecological screening are essential.
authors.affiliation: Laboratoire de microbiologie appliquée à l'agro-alimentaire, au biomédical et à l'environnement (LAMAABE), université de Tlemcen, Ex. complexe biomédical, Imama, Bloc C, BP 119, 13000 Tlemcen, Algeria. Electronic address: aitsalemnabila@hotmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Masdoua
authors.affiliation: Laboratoire de microbiologie appliquée à l'agro-alimentaire, au biomédical et à l'environnement (LAMAABE), université de Tlemcen, Ex. complexe biomédical, Imama, Bloc C, BP 119, 13000 Tlemcen, Algeria.
authors.forename: L
authors.initials: L
authors.lastname: Boublenza
authors.affiliation: Laboratoire de microbiologie appliquée à l'agro-alimentaire, au biomédical et à l'environnement (LAMAABE), université de Tlemcen, Ex. complexe biomédical, Imama, Bloc C, BP 119, 13000 Tlemcen, Algeria.
authors.forename: H
authors.initials: H
authors.lastname: Hassaine
authors.affiliation: Unité Inserm 1058, université de Montpellier, 34093 Montpellier, France.
authors.forename: J
authors.initials: J
authors.lastname: Ngou
authors.affiliation: Laboratoire de microbiologie appliquée à l'agro-alimentaire, au biomédical et à l'environnement (LAMAABE), université de Tlemcen, Ex. complexe biomédical, Imama, Bloc C, BP 119, 13000 Tlemcen, Algeria.
authors.forename: A
authors.initials: A
authors.lastname: Nahet
authors.affiliation: Unité Inserm 1058, université de Montpellier, 34093 Montpellier, France.
authors.forename: M
authors.initials: M
authors.lastname: Segondy
authors.affiliation: Service d'infectiologie, CHU d'Oran, Oran, Algeria.
authors.forename: F
authors.initials: F
authors.lastname: Razik
authors.affiliation: Service d'épidémiologie et de médecine préventive, CHU de Tlemcen, Tlemcen, Algeria.
authors.forename: D
authors.initials: D
authors.lastname: Regagba
authors.affiliation: Laboratoire Herpès virus, papillomavirus et autres, département de virologie, institut Pasteur d'Algérie, Alger, Algeria.
authors.forename: N
authors.initials: N
authors.lastname: Sadouki
authors.affiliation: Laboratoire Herpès virus, papillomavirus et autres, département de virologie, institut Pasteur d'Algérie, Alger, Algeria.
authors.forename: D
authors.initials: D
authors.lastname: Mouhammedi
mesh_terms: D000328:Adult; D000368:Aged; D000462:Algeria / Q000453:epidemiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000453:epidemiology*; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000821:virology*; D055815:Young Adult
keywords: Algeria; Algérie; HIV-1; HPV; VIH-1