title: [IgG4-associated diseases : Essentials for pathologists and radiologists].
abstract: Immunoglobulin G4-associated (IgG4) autoimmune diseases are systemic multiorgan diseases with variable clinical presentation. Principally, all organs can be affected. All IgG4-associated diseases have the same morphological correlate in common, which includes lymphoplasmacellular inflammation with abundant IgG4-positive plasma cells, obliterative phlebitis and storiform fibrosis, each with a variable manifestation. The exact pathogenesis is not yet completely understood; however, as in most cases glucocorticoids induce a prompt clinical response to therapy, this new multisystemic disease must be taken into consideration not only by pathologists but also by radiologists.
authors.affiliation: Institut für Pathologie, Ruhr-Universität Bochum, Bürkle-de-la-Camp Platz 1, 44789, Bochum, Deutschland. andrea.tannapfel@rub.de.
authors.forename: A
authors.initials: A
authors.lastname: Tannapfel
mesh_terms: D001327:Autoimmune Diseases / Q000000981:diagnostic imaging* / Q000276:immunology / Q000473:pathology*; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G
keywords: Biopsy; Lymphoplasmacellular inflammation; Multisystemic disease; Obliterative phlebitis; Storiform fibrosis