title: Melanocytic Matrical Carcinoma Mimicking Melanoma.
abstract: Melanocytic matrical carcinoma is a very uncommon malignant neoplasm with follicular differentiation. The lesion often presents as a solitary nodule on sun-exposed skin of elderly patients. Histopathologically, it is characterized by proliferation of atypical matrical cells admixed with an increased number of melanocytes, and some atypical matrical cells may have cytoplasmic pigment. When melanocytic proliferation or melanin pigment is prominent, melanocytic metrical carcinoma can mimic melanoma. Here, we present a novel case of melanocytic matrical carcinoma mimicking melanoma in an 80-year-old man with our findings in histopathologic and immunohistochemical study.
authors.affiliation: Ackerman Academy of Dermatopathology, New York, NY.|Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Ji
authors.affiliation: Ackerman Academy of Dermatopathology, New York, NY.|Department of Dermatology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Ackerman Academy of Dermatopathology, New York, NY.
authors.forename: Patricia
authors.initials: P
authors.lastname: Heller
authors.affiliation: Ackerman Academy of Dermatopathology, New York, NY.
authors.forename: Ying
authors.initials: Y
authors.lastname: Guo
mesh_terms: D000369:Aged, 80 and over; D018280:Carcinoma, Skin Appendage / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006201:Hair Diseases / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology; D018294:Neoplasms, Adnexal and Skin Appendage / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology