title: Cellular and Molecular Imaging Using Chemical Exchange Saturation Transfer.
abstract: Chemical exchange saturation transfer (CEST) is a powerful new tool well suited for molecular imaging. This technology enables the detection of low concentration probes through selective labeling of rapidly exchanging protons or other spins on the probes. In this review, we will highlight the unique features of CEST imaging technology and describe the different types of CEST agents that are suited for molecular imaging studies, including CEST theranostic agents, CEST reporter genes, and CEST environmental sensors.
authors.affiliation: *F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute †The Russell H. Morgan Department of Radiology and Radiological Sciences, Division of MR Research ‡Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD.
authors.forename: Michael T
authors.initials: MT
authors.lastname: McMahon
authors.forename: Assaf A
authors.initials: AA
authors.lastname: Gilad
mesh_terms: D003287:Contrast Media / Q000737:chemistry*; D006801:Humans; D008279:Magnetic Resonance Imaging; D057054:Molecular Imaging / Q000379:methods*; D000068936:Theranostic Nanomedicine
chemical_list: D003287:Contrast Media