title: Palladium-catalyzed direct intermolecular silylation of remote unactivated C(sp3)-H bonds.
abstract: An efficient and convenient method has been developed to achieve direct silylation of unactivated remote primary or secondary C(sp3)-H bonds to form C-Si bonds with hexamethyldisilane (HMDS). This method highlights the emerging strategy to transform unactivated methyl or methylene into versatile functional groups in organic synthesis and provides a new method to construct functionalized C-Si bonds for synthetic chemistry.
authors.affiliation: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China. zhangsy16@sjtu.edu.cn.
authors.forename: Jin-Long
authors.initials: JL
authors.lastname: Pan
authors.forename: Quan-Zhe
authors.initials: QZ
authors.lastname: Li
authors.forename: Ting-Yu
authors.initials: TY
authors.lastname: Zhang
authors.forename: Si-Hua
authors.initials: SH
authors.lastname: Hou
authors.forename: Jun-Cheng
authors.initials: JC
authors.lastname: Kang
authors.forename: Shu-Yu
authors.initials: SY
authors.lastname: Zhang