title: Executive summary of the joint position paper on renal denervation of the Cardiovascular and Interventional Radiological Society of Europe and the European Society of Hypertension.
abstract: Renal denervation (RDN) was reported as a novel exciting treatment for resistant hypertension in 2009. An initial randomized trial supported its efficacy and the technique gained rapid acceptance across the globe. However, a subsequent large blinded, sham arm randomized trial conducted in the USA (to gain Food and Drug Administration approval) failed to achieve its primary efficacy end point in reducing office blood pressure at 6 months. Published in 2014 this trial received both widespread praise and criticism. RDN has effectively stopped out with clinical trials pending further evidence. This joint consensus document representing the European Society of Hypertension and the Cardiovascular and Radiological Society of Europe attempts to distill the current evidence and provide future direction and guidance.
authors.affiliation: aInterventional Radiology, North Glasgow University Hospitals, Glasgow bDepartment of Radiology, St George's Hospital, London, United Kingdom cHypertension and Vascular Risk Unit, Department of Internal Medicine, Hospital Clínic (IDIBAPS), University of Barcelona, Barcelona, Spain dDepartment of Radiology, Beaumont Hospital, Dublin 9, Ireland eUniversity of Milano-Bicocca, Milano, Italy fDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague 4, Czech Republic gResearch Institute INCLIVA, University of Valencia and CIBERObn, ISCIII, Madrid, Spain hUniversity of Amsterdam, Department of Radiology, Academic Medical Centre Amsterdam, Amsterdam, The Netherlands iNational and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece jInstitute of Radiology, Klinikum Ingolstadt, Ingolstadt kUniversity Hospital Erlangen, Nephrology and Hypertension, Erlangen, Germany.
authors.forename: Jonathan G
authors.initials: JG
authors.lastname: Moss
authors.forename: Anna-Maria
authors.initials: AM
authors.lastname: Belli
authors.forename: Antonio
authors.initials: A
authors.lastname: Coca
authors.forename: Michael
authors.initials: M
authors.lastname: Lee
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mancia
authors.forename: Jan H
authors.initials: JH
authors.lastname: Peregrin
authors.forename: Josep
authors.initials: J
authors.lastname: Redon
authors.forename: Jim A
authors.initials: JA
authors.lastname: Reekers
authors.forename: Costas
authors.initials: C
authors.lastname: Tsioufis
authors.forename: Dierk
authors.initials: D
authors.lastname: Vorwerk
authors.forename: Roland E
authors.initials: RE
authors.lastname: Schmieder
mesh_terms: D001794:Blood Pressure; D032921:Consensus; D003329:Coronary Vasospasm / Q000601:surgery*; D003714:Denervation; D006801:Humans; D006973:Hypertension / Q000601:surgery*; D007668:Kidney / Q000294:innervation* / Q000503:physiopathology; D017410:Practice Guidelines as Topic; D003245:Consensus Statements as Topic