title: The First Reported Case of Recurrent Carcinoid Tumor in the External Auditory Canal.
abstract: Cutaneous neuroendocrine lesions of the external auditory canal (EAC) are exceptionally rare, with only five cases reported in the literature. In this case report, we present a patient with a recurrent carcinoid tumor in the EAC, which has yet to be described.
  
  
  
  A 38-year-old woman presenting with otalgia, aural fullness, and decreased hearing was found to have a recurrent EAC carcinoid tumor, 8-years after initial resection at an outside facility.
  
  
  
  The recurrent tumor involved much of the proximal, anterior bony ear canal and was trans-tympanic, extending to the middle ear and epitympanum; therefore, a lateral temporal bone resection was performed to ensure complete resection.
  
  
  
  Surgical pathology confirmed the presence a recurrent carcinoid tumor in the EAC, with immunohistochemistry positive for pancytokeratin (MAK6), CD56, and synaptophysin, with chromogranin showing rare cells positive for cytoplasmic granules. There was no evidence of metastasis.
  
  
  
  Lateral temporal bone resection was successful and the patient is being followed with annual imaging. The patient is considering future hearing rehabilitation with a bone anchored hearing device.
  
  
  
  This case report highlights the first known case of recurrent carcinoid tumor in the EAC, treated with lateral temporal bone resection. Clinical presentation, imaging, treatment, and pathology are reviewed along with a review of the literature.
authors.affiliation: *The University of Arizona College of Medicine †Department of Otolaryngology-Head and Neck Surgery ‡Department of Pathology §Department of Medical Imaging, University of Arizona College of Medicine, Tucson, Arizona.
authors.forename: Hilary C
authors.initials: HC
authors.lastname: McCrary
authors.forename: Erynne A
authors.initials: EA
authors.lastname: Faucett
authors.forename: Saranya
authors.initials: S
authors.lastname: Reghunathan
authors.forename: F Zahra
authors.initials: FZ
authors.lastname: Aly
authors.forename: Rihan
authors.initials: R
authors.lastname: Khan
authors.forename: Raymond F
authors.initials: RF
authors.lastname: Carmody
authors.forename: Abraham
authors.initials: A
authors.lastname: Jacob
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002276:Carcinoid Tumor / Q000473:pathology*; D004424:Ear Canal / Q000473:pathology / Q000601:surgery; D004428:Ear Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009364:Neoplasm Recurrence, Local / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor