title: VOLUME-RENDERED ANGIOGRAPHIC AND STRUCTURAL OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF MACULAR TELANGIECTASIA TYPE 2.
abstract: OBJECTIVE
  To evaluate multimodal imaging including volume-rendered angiographic and structural optical coherence tomography of macular telangiectasia Type 2 (MacTel2) for right-angle vein complexes, macular cavitations, and signs of deeper retinal vascular invasion.
  
  
  METHODS
  Retrospective review of imaging performed in a community-based retinal referral center. The eyes were scanned using optical coherence tomography using split-spectrum amplitude-decorrelation techniques to derive flow information. These data were extracted and used to create volume-rendered images of the retinal vasculature with integrated structural information derived from the component optical coherence tomographic images.
  
  
  RESULTS
  There were 24 eyes of 16 patients who had a mean age of 61.8 years. Right-angle veins seemed in association with vascular proliferation external to the deep vascular plexus. The origin of a right-angle vein was surrounded by a stellate arrangement of radiating retinal vessels apparently caused by contraction of surrounding tissue in the temporal macula. Cavitations were found in the fovea and varied in size and configuration from one examination to the next. Many smaller cavitations, called microcavitations, were seen in the surrounding macula. Vascular invasion occurred into the subretinal space.
  
  
  CONCLUSIONS
  There are contractile features of the tissue in the temporal macula and the number, size, and temporal variations in the cavitations have not been in not mentioned in previous published descriptions of MacTel2. Vascular invasion of deeper layers occurred in the temporal macula through the outer nuclear layer. Volume-rendered angiographic and structural optical coherence tomography offers unprecedented ability to examine the vascular interrelationships their associations with cavitations in the macula.
authors.affiliation: *Vitreous, Retina, Macula Consultants of New York, New York, New York; †The LuEster T. Mertz Retina Research Laboratory, New York, New York; and ‡Department of Ophthalmology, Fondation Asile des Aveugles, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland.
authors.forename: Richard F
authors.initials: RF
authors.lastname: Spaide
authors.forename: Mihoko
authors.initials: M
authors.lastname: Suzuki
authors.forename: Lawrence A
authors.initials: LA
authors.lastname: Yannuzzi
authors.forename: Alexandre
authors.initials: A
authors.lastname: Matet
authors.forename: Francine
authors.initials: F
authors.lastname: Behar-Cohen
mesh_terms: D000368:Aged; D000072226:Computed Tomography Angiography; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D015861:Retinal Neovascularization / Q000175:diagnosis*; D058456:Retinal Telangiectasis / Q000175:diagnosis*; D012171:Retinal Vessels / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence