title: [Effect of extent of glottal incompetence on phonation in excised canine larynx models].
abstract: Objective:To compare the acoustic signal, mucosal wave and aerodynamic parameter (phonation threshold pressure, PTP) under different sub-glottal pressure (SGP) on the excised canine models with different extent of glottal incompetence.Methods:Perturbation measures and nonlinear dynamic measures were applied to analyze the acoustic signal (jitter, shimmer), mucosal wave [frequency(F), amplitude(A), phase(P)] and PTP from our study including 11 excised canine larynges with different extent of glottal incompetence (0 mm, 1 mm, 2 mm, 3 mm,n=11, respectively) under 1-4 kPa sub-glottal pressure.Results:There were significant differences between different groups in jitter, shimmer, amplitude, frequency and PTP under various SGPs and extent of glottal incompetence (allP<0.05), inversely, there was no significant difference inPbetween groups (P>0.05). Jitter and shimmer changed obviously when the SGP increased to 3 kPa in the control group and GI 1 mm group. Jitter and shimmer changed obviously when the SGP increased to 2 kPa in the GI 2 mm and 3 mm groups. The F and A of mucosal wave increased with increasing SGP, decreased with increasing GI, and thePchanged irregularly. There was statistically significant difference of PTP between different GI groups.Conclusions:The SGP and the extent of GI had obvious affection on the the acoustic signal, mucosal wave and aerodynamic parameters.
authors.affiliation: Department of Clinical Medicine, College of Medicine, Xiamen University, Xiamen 361005, China.
authors.forename: G H
authors.initials: GH
authors.lastname: Hou
authors.affiliation: Department of Clinical Medicine, College of Medicine, Xiamen University, Xiamen 361005, China.
authors.forename: R Q
authors.initials: RQ
authors.lastname: Wang
authors.affiliation: Department of Applied Marine Physics & Engineering, College of Ocean and Earth Science, Xiamen University, Xiamen 361005, China.
authors.forename: S
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of Applied Marine Physics & Engineering, College of Ocean and Earth Science, Xiamen University, Xiamen 361005, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Otorhinolaryngology, Xiamen University Zhongshan Hospital, Xiamen 361004, China.
authors.forename: X L
authors.initials: XL
authors.lastname: Xu
authors.affiliation: Department of Otorhinolaryngology, Xiamen University Zhongshan Hospital, Xiamen 361004, China.
authors.forename: P Y
authors.initials: PY
authors.lastname: Zhuang
mesh_terms: D000162:Acoustics; D000818:Animals; D004285:Dogs; D005931:Glottis / Q000503:physiopathology*; D007825:Laryngectomy; D007830:Larynx / Q000503:physiopathology / Q000601:surgery; D010699:Phonation / Q000502:physiology*; D011312:Pressure; D014681:Velopharyngeal Insufficiency / Q000503:physiopathology