title: Primary B-Cell Mucosa-Associated Lymphoid Tissue Lymphoma of the Hard Palate and Parotid Gland: Report of One Case and Review of the Literature.
abstract: A 61-year-old woman was admitted to our hospital with an ulcerated palate mass and swelling of the right parotid gland. Incisional biopsy from the hard palate revealed an extranodal marginal zone B-cell lymphoma, also called mucosa-associated lymphoid tissue (MALT) lymphoma. Final diagnosis was MALT lymphoma of the parotid gland with concomitant involvement of an extremely seldom site of involvement: the hard palate. To our knowledge, this report illustrates the first case of MALT lymphoma of the hard palate and parotid gland without an underlying autoimmune disease. Rituximab-based combination regimen (R-CHOP) provided complete remission with total regression of mass lesions at the hard palate and parotid gland. At 44-month follow-up, there is no disease relapse. We adressed the manifestations and management of MALT lymphoma patients with involvement of salivary gland and oral cavity.
authors.affiliation: Division of Hematology, Department of Internal Medicine, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey.
authors.forename: Ipek
authors.initials: I
authors.lastname: Yonal-Hindilerden
authors.affiliation: Hematology Clinic, Istanbul Bakirkoy Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
authors.forename: Fehmi
authors.initials: F
authors.lastname: Hindilerden
authors.affiliation: Radiology Clinic, Istanbul Bakirkoy Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Arslan
authors.affiliation: Department of Pathology, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey.
authors.forename: Nalan
authors.initials: N
authors.lastname: Turan-Guzel
authors.affiliation: Department of Pathology, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey.
authors.forename: Ibrahim Oner
authors.initials: IO
authors.lastname: Dogan
authors.affiliation: Division of Hematology, Department of Internal Medicine, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey.
authors.forename: Meliha
authors.initials: M
authors.lastname: Nalcaci
keywords: Hard palate; MALT lymphoma; Parotid gland