title: Expanding nephron progenitors in vitro: a step toward regenerative medicine in nephrology.
abstract: With recent success in directed differentiation of nephron progenitors from mouse embryonic stem cells or human-induced pluripotent stem cells, the ability to expand these nephron progenitors is an important step toward regenerative medicine in nephrology. A recent publication reports the first successful attempt to propagate human nephron progenitors while retaining their potential to form both glomeruli and renal tubules.
authors.affiliation: Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Tanigawa
authors.affiliation: Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan. Electronic address: ryuichi@kumamoto-u.ac.jp.
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Nishinakamura
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques; D006801:Humans; D009398:Nephrology / Q000639:trends*; D009399:Nephrons / Q000166:cytology*; D044968:Regenerative Medicine / Q000639:trends*; D013234:Stem Cells / Q000502:physiology*