title: An usual cause of elliptocytosis.
abstract: We report a 60-year-old adult case with a normocytic normochromic regenerative anemia discovered incidentally. The objectification of elliptocytosis accompanied by splenomegaly, a collagen myelofibrosis and the presence of the mutation JAK2V617F allowed the diagnosis of primary myelofibrosis with atypical initial presentation. The causes of elliptocytoses are discussed.
authors.affiliation: Service d'hématologie biologique, Pôle laboratoires, Centre hospitalier universitaire de Nancy, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Broséus
authors.affiliation: Service d'hématologie et médecine interne, Pôle spécialités médicales, Centre hospitalier universitaire de Nancy, France.
authors.forename: Gabrielle
authors.initials: G
authors.lastname: Roth-Guépin
authors.affiliation: Service d'hématologie et médecine interne, Pôle spécialités médicales, Centre hospitalier universitaire de Nancy, France.
authors.forename: Maud
authors.initials: M
authors.lastname: D'Aveni-Piney
authors.affiliation: Service d'hématologie et médecine interne, Pôle spécialités médicales, Centre hospitalier universitaire de Nancy, France.
authors.forename: Aurore
authors.initials: A
authors.lastname: Perrot
authors.affiliation: Service d'hématologie biologique, Pôle laboratoires, Centre hospitalier universitaire de Nancy, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Lesesve
authors.affiliation: Service d'hématologie biologique, Pôle laboratoires, Centre hospitalier universitaire de Nancy, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Perrin
mesh_terms: D000740:Anemia / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D004612:Elliptocytosis, Hereditary / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D033162:Incidental Findings; D053614:Janus Kinase 2 / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009154:Mutation; D055728:Primary Myelofibrosis / Q000150:complications / Q000175:diagnosis / Q000235:genetics
chemical_list: C507924:JAK2 protein, human; D053614:Janus Kinase 2
keywords: anaemia; elliptocytes; primary myelofibrosis