title: Actinobacillus ureae:an unusual cause of tree-in-bud pattern in a case of pneumonia on lung computed tomographic scan-first clinical case report and review of the literature from India.
abstract: A 62-year-old man with asthma sought care for intermittent fever, cough with expectoration, breathlessness and orthopnoea with grunting. Computed tomography revealed clusters of centrilobular nodules on both sides with a tree-in-bud appearance and mild diffuse bronchial wall thickening. Sputum sample grew pure colonies ofActinobacillus ureaewhich was confirmed by MALDI-TOF and 16SrRNA gene sequencing. A. ureae may be an additional bacteriologic causative agent of the tree-in-bud pattern on computed tomographic scan.
authors.affiliation: Department of Microbiology, India.
authors.forename: R
authors.initials: R
authors.lastname: Dawar
authors.affiliation: Ambedkar Centre for Biomedical Research (ACBR), University of Delhi, Delhi, India.
authors.forename: D
authors.initials: D
authors.lastname: Nagarjuna
authors.affiliation: Department of Internal Medicine, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Gupta
authors.affiliation: Department of Internal Medicine, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India.
authors.forename: N P
authors.initials: NP
authors.lastname: Ghonge
authors.affiliation: Department of Microbiology, India.
authors.forename: R
authors.initials: R
authors.lastname: Sardana
keywords: 16sRNA sequencing; Actinobacillus; Bronchial asthma; MALDI-TOF; Pneumonia; Tree in bud appearance