title: Interactive knowledge discovery with the doctor-in-the-loop: a practical example of cerebral aneurysms research.
abstract: Established process models for knowledge discovery find the domain-expert in a customer-like and supervising role. In the field of biomedical research, it is necessary to move the domain-experts into the center of this process with far-reaching consequences for both their research output and the process itself. In this paper, we revise the established process models for knowledge discovery and propose a new process model for domain-expert-driven interactive knowledge discovery. Furthermore, we present a research infrastructure which is adapted to this new process model and demonstrate how the domain-expert can be deeply integrated even into the highly complex data-mining process and data-exploration tasks. We evaluated this approach in the medical domain for the case of cerebral aneurysms research.
authors.affiliation: RISC Software GmbH - Research Unit Medical Informatics, Johannes Kepler University Linz, Hagenberg, Austria. dominic.girardi@risc.uni-linz.ac.at.
authors.forename: Dominic
authors.initials: D
authors.lastname: Girardi
authors.affiliation: Institute for Application Oriented Knowledge Processing, Johannes Kepler University Linz, Linz, Austria.
authors.forename: Josef
authors.initials: J
authors.lastname: Küng
authors.affiliation: Institute for Radiology, Campus Neuromed of the Medical University Linz, Linz, Austria.
authors.forename: Raimund
authors.initials: R
authors.lastname: Kleiser
authors.affiliation: Institute for Radiology, Campus Neuromed of the Medical University Linz, Linz, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Sonnberger
authors.affiliation: Institute for Radiology, Campus Neuromed of the Medical University Linz, Linz, Austria.
authors.forename: Doris
authors.initials: D
authors.lastname: Csillag
authors.affiliation: Institute for Radiology, Campus Neuromed of the Medical University Linz, Linz, Austria.
authors.forename: Johannes
authors.initials: J
authors.lastname: Trenkler
authors.affiliation: Research Unit HCI-KDD, Institute for Medical Informatics, Statistics and Documentation, Medical University Graz, Graz, Austria.
authors.forename: Andreas
authors.initials: A
authors.lastname: Holzinger
keywords: Doctor-in-the-loop; Expert-in-the-loop; Interactive machine learning; Knowledge discovery; Medical research; Process model