title: Magnetic Resonance Imaging and Spectroscopy in Cancer Theranostic Imaging.
abstract: With its exquisite anatomical resolution and wide-ranging functional imaging capabilities, magnetic resonance imaging (MRI) has found multiple applications in detection, staging, and monitoring treatment response in cancer. The metabolic information provided by magnetic resonance spectroscopy (MRS) is being actively investigated to complement MRI parameters, as well as existing biomarkers, in cancer detection and in monitoring response to treatment. Located at the interface of detection and therapy, theranostic imaging is a rapidly expanding new field that is showing significant promise for precision medicine of cancer. Innovations in the development of novel nanoparticles decorated with imaging reporters that can be used to deliver therapeutic cargo to specific cells and environments have provided new roles for MRI and MRS in theranostic imaging.
authors.affiliation: *JHU ICMIC Program, Division of Cancer Imaging Research, Russell H. Morgan Department of Radiology and Radiological Science †Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD.
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Penet
authors.forename: Jiefu
authors.initials: J
authors.lastname: Jin
authors.forename: Zhihang
authors.initials: Z
authors.lastname: Chen
authors.forename: Zaver M
authors.initials: ZM
authors.lastname: Bhujwalla
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging / Q000639:trends; D009369:Neoplasms / Q000000981:diagnostic imaging*; D013057:Spectrum Analysis / Q000639:trends; D000068936:Theranostic Nanomedicine / Q000639:trends