title: ESTIMATING BASAL ENERGY EXPENDITURE IN LIVER TRANSPLANT RECIPIENTS: THE VALUE OF THE HARRIS-BENEDICT EQUATION.
abstract: Reliable measurement of basal energy expenditure (BEE) in liver transplant (LT) recipients is necessary for adapting energy requirements, improving nutritional status and preventing weight gain. Indirect calorimetry (IC) is the gold standard for measuring BEE. However, BEE may be estimated through alternative methods, including electrical bioimpedance (BI), Harris-Benedict Equation (HBE), and Mifflin-St. Jeor Equation (MSJ) that carry easier applicability and lower cost.
  
  
  
  To determine which of the three alternative methods for BEE estimation (HBE, BI and MSJ) would provide most reliable BEE estimation in LT recipients.
  
  
  
  Prospective cross-sectional study including dyslipidemic LT recipients in follow-up at a 735-bed tertiary referral university hospital. Comparisons of BEE measured through IC to BEE estimated through each of the three alternative methods (HBE, BI and MSJ) were performed using Bland-Altman method and Wilcoxon Rank Sum test.
  
  
  
  Forty-five patients were included, aged 58±10 years. BEE measured using IC was 1664±319 kcal for males, and 1409±221 kcal for females. Average difference between BEE measured by IC (1534±300 kcal) and BI (1584±377 kcal) was +50 kcal (p=0.0384). Average difference between the BEE measured using IC (1534±300 kcal) and MSJ (1479.6±375 kcal) was -55 kcal (p=0.16). Average difference between BEE values measured by IC (1534±300 kcal) and HBE (1521±283 kcal) was -13 kcal (p=0.326). Difference between BEE estimated through IC and HBE was less than 100 kcal for 39 of all 43patients.
  
  
  
  Among the three alternative methods, HBE was the most reliable for estimating BEE in LT recipients.
authors.affiliation: Postgraduate Program in Surgical Sciences.
authors.forename: Andressa S
authors.initials: AS
authors.lastname: Pinto
authors.affiliation: Postgraduate Program in Surgical Sciences.|Division of Gastrointestinal Surgery and Liver and Pancreas Transplantation.
authors.forename: Marcio F
authors.initials: MF
authors.lastname: Chedid
authors.affiliation: Unit of Dietary Therapy.
authors.forename: Léa T
authors.initials: LT
authors.lastname: Guerra
authors.affiliation: Division of Gastroenterology and Hepatology.
authors.forename: Mario R
authors.initials: MR
authors.lastname: Álvares-DA-Silva
authors.affiliation: Division of Gastroenterology and Hepatology.
authors.forename: Alexandre de
authors.initials: A
authors.lastname: Araújo
authors.affiliation: Division of Medical Statistics, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
authors.forename: Luciano S
authors.initials: LS
authors.lastname: Guimarães
authors.affiliation: Division of Gastrointestinal Surgery and Liver and Pancreas Transplantation.
authors.forename: Ian
authors.initials: I
authors.lastname: Leipnitz
authors.affiliation: Division of Gastrointestinal Surgery and Liver and Pancreas Transplantation.
authors.forename: Aljamir D
authors.initials: AD
authors.lastname: Chedid
authors.affiliation: Postgraduate Program in Surgical Sciences.|Division of Gastrointestinal Surgery and Liver and Pancreas Transplantation.
authors.forename: Cleber R P
authors.initials: CR
authors.lastname: Kruel
authors.affiliation: Division of Gastrointestinal Surgery and Liver and Pancreas Transplantation.
authors.forename: Tomaz J M
authors.initials: TJ
authors.lastname: Grezzana-Filho
authors.affiliation: Postgraduate Program in Surgical Sciences.|Division of Gastrointestinal Surgery and Liver and Pancreas Transplantation.
authors.forename: Cleber D P
authors.initials: CD
authors.lastname: Kruel
mesh_terms: D003430:Cross-Sectional Studies; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D055641:Mathematical Concepts; D008875:Middle Aged; D011446:Prospective Studies