title: Disparities in cancer epidemiology and care delivery among Brazilian indigenous populations.
abstract: To assess aspects related to cancer in indigenous population.
  This is a retrospective study developed in a public university hospital. We included patients with 18 or more years of age, diagnosed with solid tumors, and followed between 2005 and 2015. Clinical features were assessed by descriptive statistics, and survival was evaluated by Kaplan-Meier curves and multivariate Cox regression.
  Fifty patients were included. The cancer incidence was 15.73 per 100,000. The mean age at diagnosis was 54 years and most patients were female (58%). Cancer of the cervix (28%) and prostate (16%) were the most common. The mean time between the onset of symptoms and the diagnosis was 9 months and from diagnosis to the treatment was 3.4 months. Disease diagnosed at stage IV (17%) had worse overall survival (HR: 11.4; p<0.05). The 5-year survival rate ranged from 88% for prostate cancer to 0% for lung cancer. All 5-year survival rates were lower as compared to other populations.
  The most prevalent cancer sites were cervix and prostate. Disease stage and primary site were prognostic factors.
  Avaliar os aspectos relacionados a câncer em populações indígenas.
  Estudo retrospectivo conduzido em um hospital universitário público. Foram incluídos pacientes com 18 anos ou mais, diagnosticados com tumores sólidos e acompanhados entre 2005 e 2015. Os aspectos clínicos foram avaliados por meio de estatística descritiva, e a sobrevida foi avaliada por meio de curvas de Kaplan-Meier e regressão multivariada de Cox.
  Foram incluídos 50 pacientes. A incidência de câncer foi 15,73 por 100 mil. A média de idade ao diagnóstico foi 54 anos, e a maioria era do sexo feminino (58%). O câncer de colo uterino (28%) e o de próstata (16%) foram os mais frequentes. O tempo médio entre o início dos sintomas e o diagnóstico foi 9 meses, e entre o diagnóstico e o tratamento, de 3,4 meses. Doença diagnosticada no estágio IV (17%) resultou em pior sobrevida global (HR: 11,4; p<0,05). A sobrevida em 5 anos variou de 88% para o câncer de próstata a 0% para pulmão. Todas as taxas de sobrevida em 5 anos foram menores em comparação a outras populações.
  Os locais mais frequentes de neoplasia foram colo de útero e próstata. O estágio da doença e o sítio primário foram fatores prognósticos.
authors.affiliation: Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Pedro Nazareth
authors.initials: PN
authors.lastname: Aguiar
authors.affiliation: Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Gustavo Trautman
authors.initials: GT
authors.lastname: Stock
authors.affiliation: Centro Paulista de Oncologia, São Paulo, SP, Brazil.
authors.forename: Gilberto de Lima
authors.initials: GL
authors.lastname: Lopes
authors.affiliation: Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Michelle Samora de
authors.initials: MS
authors.lastname: Almeida
authors.affiliation: Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Hakaru
authors.initials: H
authors.lastname: Tadokoro
authors.affiliation: Universidade Paulista, São Paulo, SP, Brazil.
authors.forename: Bárbara de Souza
authors.initials: BS
authors.lastname: Gutierres
authors.affiliation: Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors.forename: Douglas Antônio
authors.initials: DA
authors.lastname: Rodrigues
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D003695:Delivery of Health Care / Q000706:statistics & numerical data; D005260:Female; D006303:Health Services, Indigenous / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007199:Indians, South American / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000453:epidemiology* / Q000208:ethnology / Q000628:therapy; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000208:ethnology / Q000473:pathology; D012189:Retrospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000208:ethnology / Q000473:pathology; D055815:Young Adult