title: Cellular Imaging With MRI.
abstract: Cellular magnetic resonance imaging (MRI) is an evolving field of imaging with strong translational and research potential. The ability to detect, track, and quantify cells in vivo and over time allows for studying cellular events related to disease processes and may be used as a biomarker for decisions about treatments and for monitoring responses to treatments. In this review, we discuss methods for labeling cells, various applications for cellular MRI, the existing limitations, strategies to address these shortcomings, and clinical cellular MRI.
authors.affiliation: *Imaging Research Laboratories, Robarts Research Institute †Department of Medical Biophysics, Western University, London, Ontario, Canada.
authors.forename: Ashley V
authors.initials: AV
authors.lastname: Makela
authors.forename: Donna H
authors.initials: DH
authors.lastname: Murrell
authors.forename: Katie M
authors.initials: KM
authors.lastname: Parkins
authors.forename: Jenna
authors.initials: J
authors.lastname: Kara
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Gaudet
authors.forename: Paula J
authors.initials: PJ
authors.lastname: Foster
mesh_terms: D000818:Animals; D002477:Cells / Q000187:drug effects; D003287:Contrast Media / Q000494:pharmacology*; D005290:Ferric Compounds / Q000494:pharmacology; D066235:Fluorine-19 Magnetic Resonance Imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D053768:Metal Nanoparticles; D013194:Staining and Labeling
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; C000499:ferric oxide