title: Factors Associated With Delayed Graft Function and Their Influence on Outcomes of Kidney Transplantation.
abstract: BACKGROUND
  One of the main postoperative complications of kidney transplant is delayed graft function (DGF), which means absence of graft function after transplant or the need for dialysis during the first week post procedure. The occurrence of DGF currently in our hospital is high and has been attributed to a combination of many factors. The aim of this study was to evaluate the factors associated to DGF and their influence in the outcome of kidney transplants.
  
  
  METHODS
  Historical cohort of 150 patients transplanted with live or deceased donor kidneys from 2011 to 2013.
  
  
  RESULTS
  DGF was associated to time in dialysis and the number of recipient pre-transplant transfusions, donors age, serum creatinine level, use of vasoactive drugs in the donor, distance from place of organ retrieval and transplant center, and duration of cold ischemia time. DGF influenced post-transplantation outcome in regard to length of stay in intensive care, length of hospital stay, acute rejection episodes, and higher creatinine levels at discharge. Patients and graft survival were shorter in the DGF group.
  
  
  CONCLUSIONS
  There are multiple factors related to DGF, the most important being those related to donors, and organ storage. The most important factor related to the recipient was the dialysis vintage. We did not find a correlation between DGF and HLA-compatibility. DGF consequences are important, including worse graft function and survival, as well as impact in recipient morbidity and mortality.
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil. Electronic address: salazarfernanda@yahoo.com.br.
authors.forename: F
authors.initials: F
authors.lastname: Salazar Meira
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil; Faculdade de Ciências Econômicas. Master in Economia Aplicada. Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
authors.forename: J
authors.initials: J
authors.lastname: Zemiacki
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil.
authors.forename: A E
authors.initials: AE
authors.lastname: Figueiredo
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil.
authors.forename: L
authors.initials: L
authors.lastname: Viliano Kroth
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Saute Kochhann
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil.
authors.forename: D O
authors.initials: DO
authors.lastname: d'Avila
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Traesel
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Saitovitch
authors.affiliation: Programa de Pós-graduação em Medicina e Ciências da Saúde da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Nephrology: FAMED, FAENFI, IPB, HSL, Porto Alegre, Brazil.
authors.forename: C E
authors.initials: CE
authors.lastname: Poli-de-Figueiredo
mesh_terms: D000328:Adult; D050377:Cold Ischemia / Q000009:adverse effects; D051799:Delayed Graft Function / Q000209:etiology*; D005260:Female; D006084:Graft Rejection / Q000209:etiology; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013997:Time Factors; D014019:Tissue Donors; D016896:Treatment Outcome