title: 7S Fragment of Type IV Collagen as a Serum Marker of Canine Liver Fibrosis.
abstract: The aim of this study was to assess whether the serum levels of the 7S fragment of type IV collagen may aid in diagnosing liver fibrosis in dogs. The study was carried out on 20 dogs with liver disease. Serum levels of the 7S fragment of type IV collagen were measured in all dogs. The analysis showed that healthy dogs and dogs with type 1, 2 and 3 liver fibrosis had low serum concentrations of the 7S fragment of type IV collagen compared to dogs with type 4 liver fibrosis. The study revealed that the assessment of serum levels of the 7S fragment of type IV collagen is useful in the diagnosis of advanced liver fibrosis and cirrhosis.
authors.forename: K
authors.initials: K
authors.lastname: Glińska-Suchocka
authors.forename: A
authors.initials: A
authors.lastname: Orłowska
authors.forename: K
authors.initials: K
authors.lastname: Kubiak
authors.forename: J
authors.initials: J
authors.lastname: Spużak
authors.forename: M
authors.initials: M
authors.lastname: Jankowski
mesh_terms: D000818:Animals; D015415:Biomarkers; D024141:Collagen Type IV / Q000737:chemistry*; D004283:Dog Diseases / Q000097:blood* / Q000175:diagnosis; D004285:Dogs; D005260:Female; D008103:Liver Cirrhosis / Q000097:blood / Q000662:veterinary*; D008297:Male
chemical_list: D015415:Biomarkers; D024141:Collagen Type IV