title: ASXL1 mutations are frequent in de novo AML with trisomy 8 and confer an unfavorable prognosis.
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Xiangping
authors.initials: X
authors.lastname: Zong
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Hong
authors.initials: H
authors.lastname: Yao
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Lijun
authors.initials: L
authors.lastname: Wen
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Liang
authors.initials: L
authors.lastname: Ma
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Qinrong
authors.initials: Q
authors.lastname: Wang
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Zhiluo
authors.initials: Z
authors.lastname: Yang
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Tongtong
authors.initials: T
authors.lastname: Zhang
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Suning
authors.initials: S
authors.lastname: Chen
authors.affiliation: a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.|b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.
authors.forename: Wu
authors.initials: W
authors.lastname: Depei
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002898:Chromosomes, Human, Pair 8 / Q000235:genetics; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007951:Leukemia, Myeloid / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011379:Prognosis; D012097:Repressor Proteins / Q000235:genetics*; D014314:Trisomy / Q000235:genetics*; D055815:Young Adult
chemical_list: C473949:ASXL1 protein, human; D012097:Repressor Proteins