title: Production of succinic acid from Basfia succiniciproducens up to the pilot scale from Arundo donax hydrolysate.
abstract: In the present work the recently isolated strain Basfia succiniciproducens BPP7 was evaluated for the production of succinic acid up to the pilot fermentation scale in separate hydrolysis and fermentation experiments on Arundo donax, a non-food dedicated energy crop. An average concentration of about 17g/L of succinic acid and a yield on consumed sugars of 0.75mol/mol were obtained demonstrating strain potential for further process improvement. Small scale experiments indicated that the concentration of acetic acid in the medium is crucial to improve productivity; on the other hand, interestingly, short-term (24h) adaptation to higher acetic acid concentrations, and strain recovery, were also observed.
authors.affiliation: Second University of Naples, Department of Experimental Medicine, Via de Crecchio 7, 80138 Naples, Italy. Electronic address: donatella.cimini@unina2.it.
authors.forename: Donatella
authors.initials: D
authors.lastname: Cimini
authors.affiliation: Second University of Naples, Department of Experimental Medicine, Via de Crecchio 7, 80138 Naples, Italy.
authors.forename: Ottavia
authors.initials: O
authors.lastname: Argenzio
authors.affiliation: Second University of Naples, Department of Experimental Medicine, Via de Crecchio 7, 80138 Naples, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: D'Ambrosio
authors.affiliation: National Research Council, Institute of Biomolecular Chemistry (ICB), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
authors.forename: Licia
authors.initials: L
authors.lastname: Lama
authors.affiliation: National Research Council, Institute of Biomolecular Chemistry (ICB), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Finore
authors.affiliation: Second University of Naples, Department of Experimental Medicine, Via de Crecchio 7, 80138 Naples, Italy.
authors.forename: Rosario
authors.initials: R
authors.lastname: Finamore
authors.affiliation: Department of Agricultural Sciences, Division of Microbiology, University of Naples Federico II, Via Università 100, 80055 Portici (Naples), Italy.
authors.forename: Olimpia
authors.initials: O
authors.lastname: Pepe
authors.affiliation: Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, via Cinthia, 4, 80126 Naples, Italy.
authors.forename: Vincenza
authors.initials: V
authors.lastname: Faraco
authors.affiliation: Second University of Naples, Department of Experimental Medicine, Via de Crecchio 7, 80138 Naples, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Schiraldi
mesh_terms: D019342:Acetic Acid; D000693:Anaerobiosis; D003470:Culture Media / Q000737:chemistry; D005285:Fermentation; D006868:Hydrolysis; D007218:Industrial Microbiology / Q000379:methods*; D015661:Pasteurellaceae / Q000378:metabolism*; D010865:Pilot Projects; D006109:Poaceae / Q000737:chemistry*; D019802:Succinic Acid / Q000378:metabolism*
chemical_list: D003470:Culture Media; D019802:Succinic Acid; D019342:Acetic Acid
keywords: Acetic acid; Arundo donax; Basfia succiniciproducens; Inhibitor; Pilot scale; Succinic acid