title: Long-term Outcomes of Pediatric Penetrating Keratoplasty for Herpes Simplex Virus Keratitis.
abstract: OBJECTIVE
  To analyze the characteristics and long-term outcomes of patients that underwent pediatric penetrating keratoplasty (PPK) for herpes simplex virus (HSV) keratitis.
  
  
  METHODS
  Retrospective, interventional, consecutive case series.
  
  
  METHODS
  Observational report of outcomes and findings for 9 patients with history of HSV keratitis that underwent PPK and were followed in a single institution. Difference between the median preoperative and final best-corrected visual acuity (BCVA) was assessed and the outcomes are reported.
  
  
  RESULTS
  We included 9 eyes; median age at the moment of the PPK was 14 years. The median initial BCVA was 20/400 (range 20/60 to hand motion) and final was 20/50 (range 20/30 to 20/400) (P < .05). Follow-up was a median of 94 months. Complications in these patients included glaucoma (1), graft rejection (1), recurrence of disease (1), and amblyopia (3). No graft failures were present.
  
  
  CONCLUSIONS
  The long-term outcomes with PPK for HSV keratitis in children provide improvement in BCVA when not compromised by amblyopia.
authors.affiliation: Department of Cornea and Refractive Surgery, Instituto de Oftalmologia "Conde de Valenciana," Mexico City, Mexico.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Serna-Ojeda
authors.affiliation: Department of Cornea and Refractive Surgery, Instituto de Oftalmologia "Conde de Valenciana," Mexico City, Mexico.
authors.forename: Denise
authors.initials: D
authors.lastname: Loya-Garcia
authors.affiliation: Department of Cornea and Refractive Surgery, Instituto de Oftalmologia "Conde de Valenciana," Mexico City, Mexico.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Navas
authors.affiliation: Department of Cornea and Refractive Surgery, Instituto de Oftalmologia "Conde de Valenciana," Mexico City, Mexico.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Lichtinger
authors.affiliation: Department of Cornea and Refractive Surgery, Instituto de Oftalmologia "Conde de Valenciana," Mexico City, Mexico.
authors.forename: Arturo
authors.initials: A
authors.lastname: Ramirez-Miranda
authors.affiliation: Department of Cornea and Refractive Surgery, Instituto de Oftalmologia "Conde de Valenciana," Mexico City, Mexico. Electronic address: egraueh@gmail.com.
authors.forename: Enrique O
authors.initials: EO
authors.lastname: Graue-Hernandez
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D007223:Infant; D016849:Keratitis, Herpetic / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D015948:Keratoplasty, Penetrating / Q000379:methods*; D008297:Male; D012008:Recurrence; D012189:Retrospective Studies; D018139:Simplexvirus; D013997:Time Factors; D014792:Visual Acuity