title: Association between the triglyceride to high-density lipoprotein cholesterol ratio and insulin resistance in Korean adolescents: a nationwide population-based study.
abstract: BACKGROUND
  Studies have suggested the triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) as a surrogate marker of insulin resistance. However, few studies have examined the association between TG/HDL-C and insulin resistance in the general adolescent population. This study aimed to examine the association between TG/HDL-C and insulin resistance in a nationally representative sample of Korean adolescents.
  
  
  METHODS
  A total of 2649 participants aged 12-18 years were selected from the 2007 to 2010 Korean National Health and Nutrition Examination Survey (KNHANES). Insulin resistance was defined as the homeostatic model assessment of insulin resistance (HOMA-IR) values greater than the 80th percentile.
  
  
  RESULTS
  The mean values of most cardiometabolic variables increased proportionally with TG/HDL-C quartiles. Compared to individuals in the lowest TG/HDL-C quartile, the odds ratio for insulin resistance for individuals in the highest quartile was 2.91 in boys and 2.38 in girls after adjusting for confounding variables.
  
  
  CONCLUSIONS
  This study suggests that TG/HDL-C could be a convenient marker for identifying Korean adolescents with insulin resistance.
authors.forename: Jae-Min
authors.initials: JM
authors.lastname: Park
authors.forename: Jee-Yon
authors.initials: JY
authors.lastname: Lee
authors.forename: Jae June
authors.initials: JJ
authors.lastname: Dong
authors.forename: Duk-Chul
authors.initials: DC
authors.lastname: Lee
authors.forename: Yong-Jae
authors.initials: YJ
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000067697:Adolescent Health / Q000208:ethnology; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000150:complications / Q000453:epidemiology / Q000208:ethnology / Q000378:metabolism*; D002648:Child; D008076:Cholesterol, HDL / Q000097:blood*; D015986:Confounding Factors, Epidemiologic; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000208:ethnology; D008297:Male; D009749:Nutrition Surveys; D050177:Overweight / Q000150:complications / Q000453:epidemiology / Q000208:ethnology / Q000378:metabolism*; D063766:Pediatric Obesity / Q000150:complications / Q000453:epidemiology / Q000208:ethnology / Q000378:metabolism*; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood*; D055105:Waist Circumference / Q000208:ethnology
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; D014280:Triglycerides