title: Late Presentation of HIV Infection: Prevalence, Trends, and the Role of HIV Testing Strategies in Guangzhou, China, 2008-2013.
abstract: Background. The prevalence, trends, and the role of different HIV testing strategies in late presentation of HIV infection in China were unknown.Methods. Data of newly reported HIV cases in Guangzhou between 2008 and 2013 was analyzed to examine the prevalence, trends, and characteristics of late presentation of HIV infection by three types of HIV testing strategies.Results. Overall, 53.2% (1412/2653) and 27.3% (724/2653) met the criteria of late presentation and presentation with advanced HIV disease. The overall trend of late presentation of HIV infection within the study period was declining. Late presentation was 62.9% in 2008 and dropped to 43.3% in 2013 (P< 0.001); presentation with advanced HIV disease was 40.3% in 2008 and dropped to 15.2% in 2013 (P< 0.001). Of the three testing strategies, PITC presented higher odds of both late presentation [AOR (95% CI): PITC versus VCT: 1.37 (1.09, 1.73); PITC versus MHT: 3.09 (2.16, 4.42)] and presentation with advanced HIV disease [AOR (95% CI): PITC versus VCT: 1.65 (1.29, 2.11); PITC versus MHT: 13.14 (8.47, 20.39)].Conclusions. Although the late presentation of HIV infection was declining, it was still high in Guangzhou. The worse situation among PITC cases urges the policy adjustment in medical settings to increase early HIV diagnosis.
authors.affiliation: Department of AIDS/STD Control and Prevention, Guangzhou Center for Disease Control and Prevention, No. 1, Qide Road, Jiahe, Baiyun District, Guangzhou, Guangdong Province 510440, China.
authors.forename: Weibin
authors.initials: W
authors.lastname: Cheng
authors.affiliation: University of North Carolina Project-China, No. 2, Lujing Road, Yuexiu District, Guangzhou, Guangdong Province 510095, China.
authors.forename: Weiming
authors.initials: W
authors.lastname: Tang
authors.affiliation: Department of AIDS/STD Control and Prevention, Guangzhou Center for Disease Control and Prevention, No. 1, Qide Road, Jiahe, Baiyun District, Guangzhou, Guangdong Province 510440, China.
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Han
authors.affiliation: University of North Carolina Project-China, No. 2, Lujing Road, Yuexiu District, Guangzhou, Guangdong Province 510095, China.
authors.forename: Thitikarn May
authors.initials: TM
authors.lastname: Tangthanasup
authors.affiliation: Department of AIDS/STD Control and Prevention, Guangzhou Center for Disease Control and Prevention, No. 1, Qide Road, Jiahe, Baiyun District, Guangzhou, Guangdong Province 510440, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Zhong
authors.affiliation: Department of AIDS/STD Control and Prevention, Guangzhou Center for Disease Control and Prevention, No. 1, Qide Road, Jiahe, Baiyun District, Guangzhou, Guangdong Province 510440, China.
authors.forename: Faju
authors.initials: F
authors.lastname: Qin
authors.affiliation: Department of AIDS/STD Control and Prevention, Guangzhou Center for Disease Control and Prevention, No. 1, Qide Road, Jiahe, Baiyun District, Guangzhou, Guangdong Province 510440, China.
authors.forename: Huifang
authors.identifier: 0000-0002-9492-5690
authors.initials: H
authors.lastname: Xu
mesh_terms: D015492:AIDS Serodiagnosis / Q000379:methods*; D000293:Adolescent; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D015496:CD4-Positive T-Lymphocytes / Q000821:virology; D002681:China / Q000453:epidemiology; D002947:Cities; D003140:Communicable Disease Control / Q000379:methods; D003625:Data Collection; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D015995:Prevalence; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents