title: Rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation in Saudi Arabia.
abstract: Rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) is a rare disease, but could be fatal if not diagnosed early. It mimics many other diseases and it may take few years after the onset of rapid obesity to have the other clinical features. Therefore, any patient with rapid-onset obesity after the age of 2 years should have high index of suspicion and long term follow up. We report a case of ROHHAD in Saudi Arabia and we highlight the clinical features and the importance of early diagnosis and management.
authors.affiliation: Department of Pediatric, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail. dr.adelalharbi@gmail.com.
authors.forename: Adel S
authors.initials: AS
authors.lastname: Al-Harbi
authors.forename: Abdullah
authors.initials: A
authors.lastname: Al-Shamrani
authors.forename: Baha A
authors.initials: BA
authors.lastname: Al-Shawwa
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000175:diagnosis*; D015992:Body Mass Index; D002648:Child; D042241:Early Diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007027:Hypothalamic Diseases / Q000175:diagnosis*; D007040:Hypoventilation / Q000175:diagnosis*; D009035:Mothers; D010845:Obesity Hypoventilation Syndrome / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D010375:Pedigree; D011175:Positive-Pressure Respiration / Q000379:methods; D012529:Saudi Arabia; D016896:Treatment Outcome