title: Intracystic Primary Squamous Cell Carcinoma of the Breast: A Challenging Diagnosis.
abstract: We report a case of a 36-year-old woman that presented with a painful mass in the outer quadrants of the left breast that had grown rapidly. Physical examination revealed a well circumscribed elastic mass and breast ultrasound showed a cyst measuring 26 mm with vegetation growing on the inner wall. Microscopic evaluation, after fine needle aspiration cytology (FNAC), suggested benign lesion. Tumorectomy was performed and the final diagnosis was a pure squamous cell carcinoma (SCC) of the breast. A simple mastectomy with sentinel node biopsy was performed. The histological study of the specimen revealed residual SCC and the sentinel lymph node was negative. The patient received 6 cycles of adjuvant chemotherapy and adjuvant radiotherapy. Four years later, the patient is free of disease.
authors.affiliation: Gynaecology Service, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
authors.forename: Vera
authors.identifier: 0000-0003-3367-993X
authors.initials: V
authors.lastname: Ramos
authors.affiliation: Pathology Service, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
authors.forename: João
authors.initials: J
authors.lastname: Fraga
authors.affiliation: Pathology Service, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
authors.forename: Teresa
authors.initials: T
authors.lastname: Simões
authors.affiliation: Gynaecology Service, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
authors.forename: Margarida
authors.identifier: 0000-0001-8396-2667
authors.initials: M
authors.lastname: Figueiredo Dias