title: Wide discrepancies in activated clotting times measured by two devices were detected for a patient with lupus anticoagulant in a cardiac surgery.
abstract: For a patient with lupus anticoagulant (LA), activated coagulation time (ACT) was measured with two different types of devices (HEMOCHRON®801 and HEMOCHRON®Jr).
  ACTs during heparinization measured with the HEMOCHRON®801 were over the range of measurement, while those with the HEMOCHRON®Jr. reflected an almost normal response to heparin.
  The phospholipid contained in an activating agent of the HEMOCHRON®Jr was suggested to have counteracted the effect of LA.
  It was indicated that the coagulation status for LA-positive patients might be better assessed by ACT measured with phospholipid in an activating agent, although careful interpretation is required.
authors.affiliation: Department of Anesthesiology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
authors.forename: Keika
authors.initials: K
authors.lastname: Miyazawa
authors.affiliation: Department of Anesthesiology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Otsuka
authors.affiliation: Department of Anesthesiology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Ishiguro
keywords: activated clotting time; antiphospholipid syndrome; cardiac surgery; lupus anticoagulant; phospholipid