title: Crohn's disease-associated interstitial lung disease mimicking sarcoidosis: a case report and review of the literature.
abstract: Respiratory involvement in Crohn's disease (CD) is a rare manifestation known to involve the large and small airways, lung parenchyma, and pleura. The clinical presentation is nonspecific, and diagnostic tests can mimic other pulmonary diseases, posing a diagnostic challenge and delay in treatment. We report a case of a 60-year-old female with a history of CD and psoriatic arthritis who presented with dyspnea, fever, and cough with abnormal radiological findings. Diagnostic testing revealed an elevated CD4:CD8 ratio in the bronchoalveolar lavage fluid, and cryoprobe lung biopsy results showed non-necrotizing granulomatous inflammation. We describe here the second reported case of pulmonary involvement mimicking sarcoidosis in Crohn's disease and a review of the literature on the approaches to making a diagnosis of CD-associated interstitial lung disease.
authors.affiliation: University of Utah. cthao@medicine.nevada.edu.
authors.forename: Choua
authors.initials: C
authors.lastname: Thao
authors.forename: Amir
authors.initials: A
authors.lastname: Lagstein
authors.forename: Tadashi
authors.initials: T
authors.lastname: Allen
authors.forename: Huseyin Erhan
authors.initials: HE
authors.lastname: Dincer
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Kim
mesh_terms: D001706:Biopsy; D003424:Crohn Disease / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000503:physiopathology; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D008875:Middle Aged; D011237:Predictive Value of Tests; D012129:Respiratory Function Tests; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
keywords: Interstitial lung disease, Crohns disease, Sarcoidosis, Cryoprobe lung biopsy.