title: NMR solution structure study of one saturated sulphur-containing amides from Glycosmis lucida.
abstract: One sulphur-containing amide (N-[2-(4-Hydroxyphenyl)-ethyl]-3-methanesulfonyl-N-methyl-propionamide) which was isolated from Glycosmis lucida Wall ex Huang had a different NMR profile with this kind of compounds' normal case. Based on the information obtained by nuclear magnetic resonance pectroscopy (NMR) and mass spectrometry (MS), its configurations in solution were investigated. The results indicated that the compound would have two stable configurations in solution as the double bond switched between C-N and C-O in an appropriate rate. This phenomenon was clearly exposed by the one dimension selective NOE (1D-NOE) experiments. This conclusion would play an active role in the structure analysis work of this kind of compounds.
authors.affiliation: a State Key Laboratory of Earth Surface Processes and Resource Ecology , Beijing Normal University , Beijing , China.|b Analytic and Testing Center , Beijing Normal University , Beijing , China.
authors.forename: Zhu-Feng
authors.initials: ZF
authors.lastname: Geng
authors.affiliation: a State Key Laboratory of Earth Surface Processes and Resource Ecology , Beijing Normal University , Beijing , China.
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.affiliation: c College of Chemistry , Beijing Normal University , Beijing , China.
authors.forename: Yin-Ping
authors.initials: YP
authors.lastname: Li
authors.affiliation: a State Key Laboratory of Earth Surface Processes and Resource Ecology , Beijing Normal University , Beijing , China.
authors.forename: Shan-Shan
authors.initials: SS
authors.lastname: Guo
authors.affiliation: a State Key Laboratory of Earth Surface Processes and Resource Ecology , Beijing Normal University , Beijing , China.
authors.forename: Chun-Xue
authors.initials: CX
authors.lastname: You
authors.affiliation: a State Key Laboratory of Earth Surface Processes and Resource Ecology , Beijing Normal University , Beijing , China.
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Zhang
authors.affiliation: a State Key Laboratory of Earth Surface Processes and Resource Ecology , Beijing Normal University , Beijing , China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: a State Key Laboratory of Earth Surface Processes and Resource Ecology , Beijing Normal University , Beijing , China.
authors.forename: Shu-Shan
authors.initials: SS
authors.lastname: Du
mesh_terms: D000577:Amides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013058:Mass Spectrometry; D015394:Molecular Structure; D027821:Rutaceae / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry; D013455:Sulfur / Q000737:chemistry
chemical_list: D000577:Amides; C000618955:N-(2-(4-Hydroxyphenyl)-ethyl)-3-methanesulfonyl-N-methyl-propionamide; D013449:Sulfonamides; D013455:Sulfur
keywords: NMR; NOE; solution structure; sulphur-containing amides