title: Treatment of Acute Ischemic Stroke.
abstract: Although stroke declined from the third to fifth most common cause of death in the United States, the annual incidence and overall prevalence continue to increase. Since the available US Food and Drug Administration-approved treatment options are time dependent, improving early stroke care may have more of a public health impact than any other phase of care. Timely and efficient stroke treatment should be a priority for emergency department and prehospital providers. This article discusses currently available and emerging treatment options in acute ischemic stroke focusing on the preservation of salvageable brain tissue, minimizing complications, and secondary prevention.
authors.affiliation: Department of Emergency Medicine, The Warren Alpert Medical School of Brown University, 55 Claverick Street, 2nd Floor, Providence, RI 02903, USA. Electronic address: Matthew_Siket@brown.edu.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Siket
mesh_terms: D000208:Acute Disease; D002545:Brain Ischemia / Q000628:therapy*; D004636:Emergency Service, Hospital; D006801:Humans; D015424:Reperfusion; D020521:Stroke / Q000628:therapy*; D015912:Thrombolytic Therapy; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D010959:Tissue Plasminogen Activator
keywords: Acute ischemic stroke; Endovascular therapy; Intravenous thrombolysis; Reperfusion; Tissue plasminogen activator