title: Intraoperative electrophysiological evaluations of macular function during peripheral scleral indentation.
abstract: Scleral indentation is widely used to examine the peripheral fundus, however it can increase the intraocular pressure (IOP) to high levels which can then affect retinal function. We evaluated the effects of scleral indentation on the macular function electrophysiologically. Intraoperative focal macular electroretinograms (iFMERGs) were recorded with and without controlling the IOP in 7 eyes. Without IOP control, the IOP increased from 21.7 ± 4.9 to 92.7 ± 20.2 mmHg significantly (P = 0.020) and the amplitudes of the b-wave (from 6.29 ± 1.160 to 3.71 ± 1.98 uV, P = 0.007), on-photopic negative response (from 2.29 ± 0.99 to 0.72 ± 0.47 uV, on-PhNR, P = 0.005), and d-wave (from 2.57 ± 0.41 to 1.64 ± 0.69 uV, P = 0.007) decreased significantly soon after beginning the indentation. All values returned to the baseline levels after releasing the indentation. In the eyes with IOP controlled, the IOP and the amplitude of all components did not change significantly during and after the indentation except the on-PhNR amplitude which was significantly reduced during the indentation. The changes in the iFMERGs and macular function caused by scleral indentation were transient and reversible. The changes can be minimized by controlling the IOP.
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Goichi
authors.initials: G
authors.lastname: Akiyama
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 173-8605, Japan.|Matsumoto Eye Clinic, Tokushima, Japan.
authors.forename: Celso Soiti
authors.initials: CS
authors.lastname: Matsumoto
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Shinoda
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Gaku
authors.initials: G
authors.lastname: Terauchi
authors.affiliation: Matsumoto Eye Clinic, Tokushima, Japan.
authors.forename: Harue
authors.initials: H
authors.lastname: Matsumoto
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Emiko
authors.initials: E
authors.lastname: Watanabe
authors.affiliation: Division of Molecular and Cellular Biology, National Institute of Sensory Organs National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Iwata
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 173-8605, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Mizota
authors.affiliation: Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
authors.forename: Yozo
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004596:Electroretinography; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008266:Macula Lutea / Q000293:injuries* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D012591:Scleral Buckling / Q000009:adverse effects*; D014065:Tonometry, Ocular