title: Goal-directed fluid management in free flap surgery for cancer of the head and neck.
abstract: BACKGROUND
  Goal-directed fluid management using stroke volume variation (SVV) analysis is not well studied in free flap reconstruction surgery in patients with head and neck cancer.
  
  
  METHODS
  Patients operated due to cancer of the head and neck with free flap reconstruction during 2008-2010 and 2012-2014 in Oulu University Hospital were retrospectively evaluated to determine the impact of SVV-guided fluid management on perioperative fluid balance, postoperative complications and hospital length of stay (LOS).
  
  
  RESULTS
  A total of 104 patients were included in the study and in 48 of them SVV was used to guide intraoperative fluid management. The SVV-guided fluid management led to significant reduction in intraoperative fluid load (6070 mL vs. 8185 mL) and hospital length of stay (11.5 vs. 14.0 days). There was no difference in the number of postoperative complications between the groups.
  
  
  CONCLUSIONS
  The SVV-guided fluid management reduces fluid administration in free flap reconstruction surgery with head and neck cancer.
authors.affiliation: Department of Anesthesia, Oulu University Hospital, Oulu, Finland - sanna.lahtinen@ppshp.fi.|Medical Research Centre and Research Group of Surgery, Anesthesia and Intensive Care, University of Oulu and Oulu University Hospital, Oulu, Finland - sanna.lahtinen@ppshp.fi.
authors.forename: Sanna L
authors.initials: SL
authors.lastname: Lahtinen
authors.affiliation: Medical Research Centre and Research Group of Surgery, Anesthesia and Intensive Care, University of Oulu and Oulu University Hospital, Oulu, Finland.|Department of Anesthesia, Division of Intensive Care Medicine, Oulu University Hospital, Oulu, Finland.
authors.forename: Janne H
authors.initials: JH
authors.lastname: Liisanantti
authors.affiliation: Department of Anesthesia and Intensive Care, Lapland Central Hospital, Rovaniemi, Finland.
authors.forename: Meri M
authors.initials: MM
authors.lastname: Poukkanen
authors.affiliation: Department of Anesthesia, Oulu University Hospital, Oulu, Finland.|Medical Research Centre and Research Group of Surgery, Anesthesia and Intensive Care, University of Oulu and Oulu University Hospital, Oulu, Finland.
authors.forename: Päivi A
authors.initials: PA
authors.lastname: Laurila
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D058752:Free Tissue Flaps / Q000601:surgery*; D006040:Goals; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D007430:Intraoperative Care; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D013318:Stroke Volume; D014882:Water-Electrolyte Balance