title: Rejuvenation of the perioral and lip regions with two new dermal fillers: The Italian experience with Vycross™Technology.
abstract: BACKGROUND
  Hyaluronic acid fillers are frequently used for maintenance of youthful appearance of perioral and lip region. The introduction of Juvederm®Volbella™with lidocaine and Juvederm®Volift™with lidocaine to the European aesthetic market in 2012 increased the options of fillers to be used and it appears to be a new solution to improve this area.
  
  
  OBJECTIVE
  the aim of this study is to demonstrate how to correct this area using two new dermal fillers: Juvederm®Volift™with lidocaine, and Juvederm®Volbella™with lidocaine, based on the experience of two Italian phycians.
  
  
  METHODS
  510 patients were enrolled, 195 were treated with Juvederm®Volbella™with Lidocaine, 160 with Juvederm®Volift™with lidocaine and 150 with both dermal fillers. Patients were photographed before and immediately after the treatment.
  
  
  RESULTS
  All patients were extremely satisfied with their treatments. There were no immediate or delayed complications with either of the dermal fillers when used alone, or in combination.
  
  
  CONCLUSIONS
  The dermal filler portfolio in Europe is among the largest and most varied available. ( 5 ) We propose here two new 15mg/ml and 17.5mg/ml hyaluronic acid fillers that utilize Vycross™technology, that are suitable for lip and perioral region. According to the severity of the wrinkles and to the lip augmentation that we want to obtain we can select either one filler or another.
authors.affiliation: a Dermatologist, Private Practice , Cagliari , Italy.
authors.forename: Lucia
authors.initials: L
authors.lastname: Calvisi
authors.affiliation: b SUNY Downwnstate Medical Center , Brooklyn , New York, USA.
authors.forename: Erin
authors.initials: E
authors.lastname: Gilbert
authors.affiliation: c Plastic Surgeon , Verona , Italy.
authors.forename: Davide
authors.initials: D
authors.lastname: Tonini
mesh_terms: D000328:Adult; D000779:Anesthetics, Local; D000067548:Dermal Fillers / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007558:Italy; D008012:Lidocaine; D008046:Lip; D008875:Middle Aged; D060052:Nasolabial Fold; D017060:Patient Satisfaction; D010781:Photography; D012060:Rejuvenation
chemical_list: D000779:Anesthetics, Local; D000067548:Dermal Fillers; D008012:Lidocaine
keywords: Dermal fillers; Juvederm Volbella with lidocaine; Juvederm Volift with lidocaine; hyaluronic acid