title: Extracorporeal membrane oxygenation treatment of a H7N9-caused respiratory failure patient with mechanical valves replacement history: A case report.
abstract: BACKGROUND
  Patients with respiratory failure caused by H7N9 may benefit from veno-venous, veno-arterial, and veno-veno-arterial extracorporeal membrane oxygenation (ECMO) support.
  
  
  METHODS
  A 55-year-old male patient was suffering from H7N9-caused acute respiratory distress syndrome (ARDS). He had a mechanical mitral and aortic valve replacement surgery and was using warfarin for anticoagulation. After prolonged mechanical ventilation, oxygen saturation was not improved. Veno-veno ECMO was then applied. After 16 days of extracorporeal life support, the patient successfully weaned from ECMO, with relatively good pulmonary recovery.
  
  
  CONCLUSIONS
  This report demonstrates that ECMO support can help treating life-threatening diseases such as H7N9-associated ARDS. Because of his special mitral and aortic valve replacement surgery history and long duration of mechanical ventilation before ECMO, we report it as a separate case, hoping to provide some reference for ECMO treatment.
authors.affiliation: Department of Cardiothoracic Surgery, the First Affiliated Hospital, Zhejiang University Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.
authors.forename: Linfeng
authors.initials: L
authors.lastname: Qian
authors.forename: Junnan
authors.initials: J
authors.lastname: Zheng
authors.forename: Hongfei
authors.initials: H
authors.lastname: Xu
authors.forename: Liping
authors.initials: L
authors.lastname: Shi
authors.forename: Lanjuan
authors.initials: L
authors.lastname: Li
mesh_terms: D004279:DNA, Viral / Q000032:analysis*; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D006349:Heart Valve Diseases / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006801:Humans; D064766:Influenza A Virus, H7N9 Subtype / Q000235:genetics*; D007251:Influenza, Human / Q000150:complications* / Q000175:diagnosis / Q000821:virology; D008297:Male; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D004279:DNA, Viral