title: Neurosyphilis With Normal Pressure Hydrocephalus and Dementia Paralytica: Serial Clinical, Laboratory and Radiological Correlations in the 21st Century.
abstract: We report a case of a 46-year-old man presenting with a progressive cognitive decline, ataxic gait, urinary incontinence for 4 months and neuroimaging consistent with normal pressure hydrocephalus. The atypical presentation of a progressively worsening dysphasia and a right hemiparesis dismissed as a vascular event 1 month earlier associated with normal pressure hydrocephalus prompted further investigations confirming neurosyphilis also manifesting as dementia paralytica. Treatment using consensus guidelines led to resumption of activities of daily living. Neurosyphilis, considered rare in the neuroimaging era, must still be considered a reversible cause of dementia and other neurological manifestations in contemporary neurological practice.
authors.affiliation: Neurology Unit.
authors.forename: Kamille
authors.initials: K
authors.lastname: Abdool
authors.affiliation: Neurology Unit.
authors.forename: Karan
authors.initials: K
authors.lastname: Seegobin
authors.affiliation: Neurology Unit.
authors.forename: Kanterpersad
authors.initials: K
authors.lastname: Ramcharan
authors.affiliation: Neurology Unit.
authors.forename: Adrian
authors.initials: A
authors.lastname: Alexander
authors.affiliation: Neurology Unit.
authors.forename: Leandra
authors.initials: L
authors.lastname: Julien-Legen
authors.affiliation: Infectious Disease Unit, San Fernando Teaching Hospital, University of the West Indies.
authors.forename: Stanley Lawrence
authors.initials: SL
authors.lastname: Giddings
authors.affiliation: Infectious Disease Unit, San Fernando Teaching Hospital, University of the West Indies.
authors.forename: Samuel
authors.initials: S
authors.lastname: Aboh
authors.affiliation: Radiology Department, University of the West Indies , Trinidad and Tobago.
authors.forename: Fidel
authors.initials: F
authors.lastname: Rampersad
keywords: Neuroradiology; Neurosyphilis; Normal Pressure Hydrocephalus; Syphilis