title: Fraction of Inspired Oxygen Delivered by Elisée™ 350 Turbine Transport Ventilator With a Portable Oxygen Concentrator in an Austere Environment.
abstract: BACKGROUND
  Management of critically ill patients in austere environments is a logistic challenge. Availability of oxygen cylinders for the mechanically ventilated patient may be difficult in such a context. One solution is to use a ventilator able to function with an oxygen concentrator (OC).
  
  
  METHODS
  We tested two Elisée™ 350 ventilators paired with SeQual Integra 10-OM oxygen concentrators (OC) (Chart Industries, http://www .chartindustries.com) and evaluated the delivered fraction of inspired oxygen (Fio2). Ventilators were connected to a test lung and Fio2 was measured and indicated by the ventilator. Continuous oxygen was generated by the OC from 0.5L/min to 10L/min, and administered by the specific inlet port of the ventilator. Several combinations of ventilator settings were evaluated to determine the factors affecting the delivered Fio2.
  
  
  RESULTS
  The Elisée 350 turbine ventilator is able to deliver a high Fio2 when functioning with an OC. However, modifications of the ventilator settings such as an increase in minute ventilation, inspiratory-to-expiratory ratio, and positive end-expiratory pressure affect delivered Fio2 despite steady-state oxygen flow from the concentrator.
  
  
  CONCLUSIONS
  OCs provide an alternative to oxygen cylinders for delivering high Fio2 with a turbine ventilator. Nevertheless, Fio2 must be monitored continuously, since it decreases when minute ventilation is increased.
authors.forename: Erwan
authors.initials: E
authors.lastname: d'Aranda
authors.forename: Julien
authors.initials: J
authors.lastname: Bordes
authors.forename: Boris
authors.initials: B
authors.lastname: Bourgeois
authors.forename: Jared
authors.initials: J
authors.lastname: Clay
authors.forename: Pierre
authors.initials: P
authors.lastname: Esnault
authors.forename: Pierre-Julien
authors.initials: PJ
authors.lastname: Cungi
authors.forename: Philippe
authors.initials: P
authors.lastname: Goutorbe
authors.forename: Eric
authors.initials: E
authors.lastname: Kaiser
authors.forename: Eric
authors.initials: E
authors.lastname: Meaudre
mesh_terms: D016638:Critical Illness / Q000628:therapy; D004867:Equipment Design; D006801:Humans; D008887:Military Medicine / Q000295:instrumentation*; D010102:Oxygen Inhalation Therapy / Q000295:instrumentation*; D012122:Ventilators, Mechanical; D014857:Warfare