title: Multimodality approach in the diagnosis and management of bilateral giant juvenile breast fibroadenoma.
abstract: Juvenile giant fibroadenoma is a very rare breast disease affecting young girls of premenarche and adolescent ages. It is a benign fibroepithelial tumour characterised by stromal and epithelial proliferation that causes rapidly growing breast mass. Bilateral symmetrical involvement is extremely rare. In this article, we describe this entity in a girl aged 13 years who presented with bilateral gigantically enlarged breasts. Ultrasonography and MRI showed large, multilobulated masses involving both breasts entirely. Endovascular embolisation of bilateral internal mammary arteries and lateral thoracic arteries supplying the masses was performed prior to surgery to reduce their vascularity. The patient subsequently underwent excision of bilateral breast masses and reduction mammoplasty. Histopathologically, bilateral breast masses were confirmed to be juvenile fibroadenomas.
authors.affiliation: Department of Radiology, Sri Ramachandra University Medical College, Chennai, Tamil Nadu, India.
authors.forename: Noora
authors.initials: N
authors.lastname: Rafeek
authors.affiliation: Department of Radiology, Sri Ramachandra University Medical College, Chennai, Tamil Nadu, India.
authors.forename: Rajeswaran
authors.initials: R
authors.lastname: Rangasami
authors.affiliation: Department of Plastic and Reconstructive Surgery, Sri Ramachandra University Medical College, Chennai, Tamil Nadu, India.
authors.forename: Kamakshi
authors.initials: K
authors.lastname: Dhanraj
authors.affiliation: Department of Neuro and Interventional Radiology, Sri Ramachandra University Medical College, Chennai, Tamil Nadu, India.
authors.forename: Santhosh
authors.initials: S
authors.lastname: Joseph
mesh_terms: D000293:Adolescent; D015901:Angiography, Digital Subtraction; D001706:Biopsy; D001940:Breast / Q000098:blood supply / Q000473:pathology; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D016462:Mammaplasty / Q000379:methods*; D014463:Ultrasonography