title: Diagnosis and Longitudinal Assessment of Osteoarthritis: Review of Available Imaging Techniques.
abstract: Osteoarthritis (OA) is a major chronic and global health care problem. Recent technological advances in imaging and postprocessing techniques have enhanced the understanding and characterization of the pathophysiology of this chronic and prevalent disease. Although plain radiograph remains the modality of choice for initial assessment of OA, recent studies have shown that advanced cross-sectional imaging can improve the early detection, grading, structural damage quantification, and risk stratification of OA. This article discusses the currently available evidence regarding both the conventional and novel imaging modalities that can be used for evaluation of patients with OA and its longitudinal assessment.
authors.affiliation: Division of Musculoskeletal Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, 601 North Caroline Street, JHOC 5165, Baltimore, MD 21287, USA. Electronic address: demehri2001@yahoo.com.
authors.forename: Shadpour
authors.initials: S
authors.lastname: Demehri
authors.affiliation: Department of Radiology, Quantitative Imaging Center, Boston University School of Medicine, Boston, MA, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Guermazi
authors.affiliation: Division of Rheumatology, University of Arizona Arthritis Center, University of Arizona, Tucson, AZ, USA.
authors.forename: C Kent
authors.initials: CK
authors.lastname: Kwoh
mesh_terms: D054893:Cone-Beam Computed Tomography; D018450:Disease Progression; D056973:Four-Dimensional Computed Tomography; D006801:Humans; D007596:Joints / Q000000981:diagnostic imaging*; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D010003:Osteoarthritis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011859:Radiography
keywords: 4-D CT; CBCT; Imaging; MRI; Osteoarthritis; PET; Radiographs