title: Herb-Drug Interactions: An Insight into Cardiovascular Diseases Based on Case Reports.
abstract: Cardiovascular patients frequently use herbal medicinal products, in order to contribute to the improvement of their chronic condition without medical intervention. However, they are likely to suffer from adverse effects from natural products and herb-drug interactions. In this work we present the results collected from a public campaign "Learning Health, among Plants and Medicines", carried out by the Observatory of Herb-Drug Interactions (www.oipm.uc.pt), to alert cardiovascular patients and healthcare providers for the potential occurrence of herb-drug interactions with cardiovascular therapy. From the data received, it was highlighted the prevalence of certain natural products used by many cardiovascular patients in Portugal, particularly goji berries, green tea, mangosteen and rooibos that have significant cardiovascular effects. For this reason their intake should be carefully monitored in these patients. This prevalence of consumption suggests a pattern in their use in Portugal and a prevention of herb-drug interactions should be carried out by the health professionals. The ending results also indicate that there is still a lack of knowledge about the possible risks of herbal products intake, which may adversely affect the health of any patient. Thus becomes clear the value of the role of health professionals in the screening of such interactions.
authors.affiliation: Observatory of Herb-Drug Interactions, Faculty of Pharmacy, University of Coimbra, Heath Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal.
authors.forename: Cheila
authors.initials: C
authors.lastname: Batista
authors.affiliation: Observatory of Herb-Drug Interactions, Faculty of Pharmacy, University of Coimbra, Heath Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal.
authors.forename: N R
authors.initials: NR
authors.lastname: Jesus
authors.affiliation: Observatory of Herb-Drug Interactions, Faculty of Pharmacy, University of Coimbra, Heath Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal.
authors.forename: Catia M
authors.initials: CM
authors.lastname: Silva
authors.affiliation: Coimbra Chemistry Center (FCT/UC), University of Coimbra, Rua Larga, Coimbra, Portugal.
authors.forename: Tiago P
authors.initials: TP
authors.lastname: Silva
authors.affiliation: Observatory of Herb-drug Interactions & Drug Discovery Group of Center for Pharmaceutical Studies, Laboratory of Pharmacognosy, Faculty of Pharmacy, University of Coimbra, Heath Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal.
authors.forename: Maria G
authors.initials: MG
authors.lastname: Campos
mesh_terms: D036903:Aspalathus / Q000009:adverse effects; D002318:Cardiovascular Diseases / Q000628:therapy*; D064420:Drug-Related Side Effects and Adverse Reactions; D029762:Garcinia mangostana / Q000009:adverse effects; D041743:Herb-Drug Interactions; D006801:Humans; D032305:Lycium / Q000009:adverse effects; D010946:Plants, Medicinal / Q000009:adverse effects*; D011174:Portugal; D013662:Tea / Q000009:adverse effects
chemical_list: D013662:Tea
keywords: Adverse effects; cardiovascular diseases; cardiovascular drugs; herbs; interactions; safety