title: Acute cardiac decompensation in a patient with beta-thalassemia and diabetes mellitus following cessation of chelation therapy.
abstract: Patients with higher liver iron stores are likely to have a worse cardiac outcome following noncompliance with chelation. Cardiovascular magnetic resonance identifies myocardial siderosis allowing optimization of iron chelation regimes. Diabetes puts thalassemic patients at increased risk of myocardial fibrosis. Dual chelation therapy with deferoxamine and deferiprone offers improved cardiac outcomes.
authors.affiliation: Department of Medicine King's College NHS Trust London UK.
authors.forename: Eirini
authors.initials: E
authors.lastname: Lioudaki
authors.affiliation: Department of Medicine King's College NHS Trust London UK.
authors.forename: Martin
authors.initials: M
authors.lastname: Whyte
keywords: Beta‐thalassemia major; chelation; diabetes; heart failure