title: Iliac Crest Fresh-Frozen Allografts Versus Autografts in Oral Pre-Prosthetic Bone Reconstructive Surgery: Histologic and Histomorphometric Study.
abstract: OBJECTIVE
  The aim of this work was to compare histologically bone biopsies obtained during dental implant placement in atrophic jaws reconstructed with fresh-frozen bone (FFB) or autologous bone blocks.
  
  
  METHODS
  Twenty partially or totally edentulous patients were treated either with iliac crest FFB grafts (14 patients; group A) or with iliac crest autografts (6 patients; group B). Seven to 9 months later, dental implants were placed in the reconstructed jaws and bone biopsies were harvested.
  
  
  RESULTS
  The reconstructive procedure was uneventful in 9 patients of group A and in all patients of group B. Samples from both groups did not show relevant differences concerning the proportion of lamellar bone, newly formed bone, and bone marrow. In group A, the decreasing proportion of blood vessels from the apical to the coronal portion, the larger amount of lacunae in the apical portion, and the fewer vessels in the coronal portion than in group B evoke an effort of the host bone to "integrate" the graft from the apical portion.
  
  
  CONCLUSIONS
  FFB cannot be considered as successful and safe in alveolar bone reconstruction as autogenous bone grafting.
authors.affiliation: *Associate Professor, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy. †Fellow, Unit of Oral Surgery, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy. ‡Fellow and Clinical Tutor, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy. §PhD Student, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy. ¶Post-doc, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy. ‖Associate Professor, Unit of Oral Surgery, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Dellavia
authors.forename: Michele
authors.initials: M
authors.lastname: Giammattei
authors.forename: Daniela
authors.initials: D
authors.lastname: Carmagnola
authors.forename: Federica
authors.initials: F
authors.lastname: Musto
authors.forename: Elena
authors.initials: E
authors.lastname: Canciani
authors.forename: Matteo
authors.initials: M
authors.lastname: Chiapasco
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D064591:Allografts / Q000473:pathology; D064592:Autografts / Q000473:pathology; D001706:Biopsy; D003757:Dental Implantation / Q000379:methods*; D005260:Female; D006801:Humans; D007085:Ilium / Q000637:transplantation*; D007568:Jaw / Q000473:pathology; D008297:Male; D063175:Mandibular Reconstruction / Q000379:methods*; D008875:Middle Aged; D056948:Orthognathic Surgical Procedures; D055815:Young Adult