title: Controlled Release of Antimicrobial ClO2Gas from a Two-Layer Polymeric Film System.
abstract: We report a two-component label system comprising a chlorite-containing polymer film and an acid-containing polymer film that can release antimicrobial ClO2gas upon adhering the two films together to enable a reaction of the chlorite and acid under moisture exposure. The chlorite-containing film comprises a commercial acrylate-based pressure-sensitive adhesive polymer impregnated with sodium chlorite. The acid-containing film comprises a commercial poly(vinyl alcohol) polymer loaded with tartaric acid. Both of the films were prepared on low ClO2-absorbing substrate films from stable aqueous systems of the polymers with high reagent loading. Rapid and sustained releases of significant amounts of ClO2gas from the label system were observed in an in situ quantification system using UV-vis spectroscopy. It was found that the ClO2release is slower at a lower temperature and can be accelerated by moisture in the atmosphere and the films. Controlled release of ClO2gas from the label system was demonstrated by tailoring film composition and thickness. A model was developed to extract release kinetics and revealed good conversions of the label system. This two-component system can potentially be applied as a two-part label without premature release for applications in food packaging.
authors.affiliation: The Dow Chemical Company, Core Research and Development , 1702 Building, Midland, Michigan 48674, United States.
authors.forename: Zhifeng
authors.initials: Z
authors.lastname: Bai
authors.affiliation: The Dow Chemical Company, Core Research and Development , 2301 North Brazosport Boulevard, Freeport, Texas 77541, United States.
authors.forename: Diego E
authors.initials: DE
authors.lastname: Cristancho
authors.affiliation: The Dow Chemical Company, Core Research and Development , 1702 Building, Midland, Michigan 48674, United States.
authors.forename: Aaron A
authors.initials: AA
authors.lastname: Rachford
authors.affiliation: The Dow Chemical Company, Core Research and Development , 1702 Building, Midland, Michigan 48674, United States.
authors.forename: Amy L
authors.initials: AL
authors.lastname: Reder
authors.affiliation: The Dow Chemical Company, Core Research and Development , 2301 North Brazosport Boulevard, Freeport, Texas 77541, United States.
authors.forename: Alexander
authors.initials: A
authors.lastname: Williamson
authors.affiliation: The Dow Chemical Company, Core Research and Development , 1702 Building, Midland, Michigan 48674, United States.
authors.forename: Adam L
authors.initials: AL
authors.lastname: Grzesiak
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D002712:Chlorides / Q000737:chemistry* / Q000494:pharmacology; D003692:Delayed-Action Preparations / Q000737:chemistry* / Q000494:pharmacology; D018857:Food Packaging / Q000295:instrumentation*; D005740:Gases / Q000737:chemistry / Q000494:pharmacology; D011108:Polymers / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D002712:Chlorides; D003692:Delayed-Action Preparations; D005740:Gases; D011108:Polymers; C001599:chlorite
keywords: antimicrobial polymer; chlorine dioxide; controlled release; food packaging