title: Isolation and phylogenetic analysis of canine distemper virus among domestic dogs in Vietnam.
abstract: Canine distemper virus (CDV) is one of the most serious pathogens found in many species of carnivores, including domestic dogs. In this study, hemagglutinin (H) genes were detected in five domestic Vietnamese dogs with diarrhea, and two CDVs were successfully isolated from dogs positive for H genes. The complete genome of one isolate, CDV/dog/HCM/33/140816, was determined. Phylogenetic analysis showed that all Vietnamese CDVs belonged to the Asia-1 genotype. In addition, the H proteins of Vietnamese CDV strains were the most homologous to those of Chinese CDVs (98.4% to 99.3% identity). These results indicated that the Asia-1 genotype of CDV was the predominant genotype circulating among the domestic dog population in Vietnam and that transboundary transmission of CDV has occurred between Vietnam and China.
authors.affiliation: Laboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
authors.forename: Dung Van
authors.initials: DV
authors.lastname: Nguyen
authors.forename: Junko
authors.initials: J
authors.lastname: Suzuki
authors.forename: Shohei
authors.initials: S
authors.lastname: Minami
authors.forename: Kenzo
authors.initials: K
authors.lastname: Yonemitsu
authors.forename: Nao
authors.initials: N
authors.lastname: Nagata
authors.forename: Ryusei
authors.initials: R
authors.lastname: Kuwata
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shimoda
authors.forename: Chien Kim
authors.initials: CK
authors.lastname: Vu
authors.forename: Thuy Quoc
authors.initials: TQ
authors.lastname: Truong
authors.forename: Ken
authors.initials: K
authors.lastname: Maeda
mesh_terms: D000818:Animals; D004216:Distemper / Q000235:genetics / Q000821:virology*; D004217:Distemper Virus, Canine / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D004283:Dog Diseases / Q000821:virology*; D004285:Dogs; D016679:Genome, Viral; D006389:Hemagglutinins, Viral / Q000235:genetics; D010802:Phylogeny; D014744:Vietnam
chemical_list: D006389:Hemagglutinins, Viral