title: Multislice Spiral Perfusion Computed Tomography to Assess Pancreatic Vascularity in Mild Acute Pancreatitis.
abstract: OBJECTIVE
  This study aims to use perfusion computed tomography to compare pancreatic perfusion in mild acute pancreatitis (MAP) versus normal pancreas.
  
  
  METHODS
  This observational study included 39 patients with MAP and 18 patients with normal pancreatic function. Perfusion computed tomography parameters, including blood flow (BF), blood volume (BV), mean transit time, and permeability surface area product, were compared.
  
  
  RESULTS
  Both serum and urinary amylase levels were significantly higher in patients with MAP than in controls (all Ps < 0.05). Patients with MAP showed significantly lower BF and BV and higher mean transit time and permeability surface area product than the controls (all Ps < 0.05). Correlation analysis on the 39 patients with MAP revealed negative coefficients between serum amylase level and BF and BV values.
  
  
  CONCLUSIONS
  Pancreatic perfusion seems to be poorer, and pancreatic vascular leakage may increase in MAP compared with normally functioned pancreas.
authors.affiliation: From the *Department of Radiology, Tianjin Nankai Hospital; and †Department of Radiology, Tianjin Central Hospital of Gynecology and Obstetrics, Tianjin, China.
authors.forename: Chunjiang
authors.initials: C
authors.lastname: Tian
authors.forename: Xiangfeng
authors.initials: X
authors.lastname: Xu
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000098:blood supply* / Q000000981:diagnostic imaging*; D010195:Pancreatitis / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D036542:Tomography, Spiral Computed / Q000379:methods*