title: The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report.
abstract: Abnormal uterine bleeding in a patient on maintenance hormonal therapy for breast cancer should raise concern for endometrial abnormalities including rare uterine metastasis from the breast. Hormonal receptor profile changes in metastatic lesions favoring human epidermal growth factor receptor 2 (HER2) overexpression may be involved in the pathogenesis of metastasis to the uterus.
authors.affiliation: Saba University School of Medicine The Bottom Saba Dutch Caribbean The Netherlands.
authors.forename: Melissa Y Y
authors.initials: MY
authors.lastname: Moey
authors.affiliation: Saba University School of Medicine The Bottom Saba Dutch Caribbean The Netherlands.
authors.forename: Omer A
authors.initials: OA
authors.lastname: Hassan
authors.affiliation: SSM Cancer Care St. Mary's Health Center St. Louis Missouri USA; Division of Hematology and Oncology Department of Internal Medicine Saint Louis University School of Medicine St. Louis Missouri USA.
authors.forename: Christos N
authors.initials: CN
authors.lastname: Papageorgiou
authors.affiliation: SSM Health St. Mary's Health Center St. Louis Missouri USA.
authors.forename: Stephanie L
authors.initials: SL
authors.lastname: Schnepp
authors.affiliation: SSM Health St. Mary's Health Center St. Louis Missouri USA; Division of Gynecologic Oncology Department of Obstetrics and Gynecology Saint Louis University School of Medicine St. Louis Missouri USA.
authors.forename: John T
authors.initials: JT
authors.lastname: Hoff
keywords: Human epidermal growth factor receptor 2; metastatic breast cancer; tamoxifen; uterus