title: Tau Phosphorylation-Much More than a Biomarker.
abstract: Lasagna-Reeves et al. (2016) demonstrate that preventing the kinase Nuak1 from phosphorylating the microtubule-associated protein tau reduces the level of potentially pathogenic tau species in brain, a novel therapeutic strategy that could help counteract Alzheimer's disease and several other neurological disorders.
authors.affiliation: Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.
authors.forename: Sumihiro
authors.initials: S
authors.lastname: Maeda
authors.affiliation: Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA. Electronic address: lennart.mucke@gladstone.ucsf.edu.
authors.forename: Lennart
authors.initials: L
authors.lastname: Mucke
mesh_terms: D000544:Alzheimer Disease; D015415:Biomarkers; D001921:Brain; D010766:Phosphorylation; D016875:tau Proteins
chemical_list: D015415:Biomarkers; D016875:tau Proteins