title: Scout-Based Automated Tube Potential Selection Technique (kV Assist) in Enhanced Chest Computed Tomography: Effects on Radiation Exposure and Image Quality.
abstract: OBJECTIVE
  The aim of our study was to assess radiation dose reduction and image quality for enhanced chest CT examinations with a scout-based automated tube potential selection technique (kV Assist) compared with a standard 120-kV protocol.
  
  
  METHODS
  Prospective study of enhanced chest CT examinations was performed in 100 consecutive patients with kV Assist and in 100 consecutive patients with conventional 120-kV protocol on a multislice CT (Discovery CT750 HD). The body mass index, CT dose index volume, and dose length product were recorded from the examination protocol. Image noise and CT value was measured on region of interest, signal-to-noise ratio, and contrast-to-noise ratio was calculated. The subjective image quality was assessed by two radiologists blinded to the respective protocol with the use of a 3-grade scale (3, superior quality; 2, moderate quality; 1, inferior quality).
  
  
  RESULTS
  With kV Assist, the percentages of patients being scanned using 80, 100, and 120 kV were 12.0%, 80.0%, and 8.0%, respectively. The kilovolt setting was related with body mass index (r = 0.565, P = 0.000). Compared with the conventional 120 kV protocol, kV Assist allowed for an overall average decrease of 30.6% in CT dose index volume (kV Assist, 11.05 ± 4.78 mGy; 120 kV, 15.92 ± 6.89 mGy) (P < 0.001) and 32.3% in dose length product (kV Assist, 386.41 ± 184.02 mGy cm; 120 kV, 571.14 ± 286.68 mGy cm) (P < 0.001). In the kV Assist, mean attenuation of regions of interest inside the aorta was significantly higher than that in 120-kV protocols (kV Assist, 310.27 ± 73.70 HU; 120 kV, 239.44 ± 47.65 HU) (P < 0.001), resulting in increased contrast-to-noise ratio (kV Assist, 26.69 ± 7.78; 120 kV, 21.38 ± 6.05) (P < 0.001). There was no significant difference in subjective image quality scores between the 2 groups.
  
  
  CONCLUSIONS
  The use of attenuation-based kV Assist technique enables significant dose reduction in enhanced chest CT scan while improving arterial enhancement and preserving image quality at adequate levels.
authors.affiliation: From the *Department of Diagnostic Radiology, and †PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People's Republic of China.
authors.forename: Meng
authors.initials: M
authors.lastname: Li
authors.forename: Shichao
authors.initials: S
authors.lastname: Feng
authors.forename: Ning
authors.initials: N
authors.lastname: Wu
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011829:Radiation Dosage; D000069079:Radiation Exposure / Q000706:statistics & numerical data*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D013902:Radiography, Thoracic / Q000295:instrumentation* / Q000379:methods*; D059629:Signal-To-Noise Ratio; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000379:methods*