title: The effect of tobacco use on outcomes of laparoscopic and open ventral hernia repairs: a review of the NSQIP dataset.
abstract: Tobacco smoking is a known risk factor for complications after major surgical procedures. The full effect of tobacco use on these complications has not been studied over large populations for ventral hernia repairs. This effect is more important as the preoperative conditioning, and optimization of patients is adopted. We sought to use the prospectively collected ACS-NSQIP dataset to evaluate respiratory and infectious complications for patients undergoing both laparoscopic and open ventral hernia repairs.
  
  
  
  The ACS-NSQIP dataset was queried for patients who underwent open or laparoscopic ventral hernia repairs, by primary procedure CPT codes, between years 2009-2012. Smoking use was registered as defined by the ACS-NSQIP, as both a current smoker (within the prior 12 months) or as a history of smoking (having ever smoked). Univariate and multivariate analyses were used to investigate postoperative complications for 30-day morbidity and mortality by smoking status while adjusting for preoperative risk factors.
  
  
  
  The majority of cases were open, 82 %, compared to laparoscopic 18 %. Sex was evenly distributed with 58 % female and 42 % male; however, there was a difference in the distribution of current smokers (p = 0.03). On analysis there were significantly more respiratory complications (p = 0.0003) and infectious complications (p < 0.0001). When controlling for sex, age, and type of surgery, using logistic regression, there were associations between smoking in the prior 12 months and respiratory complications, including pneumonia (p < 0.0001), and re-intubation (p < 0.0001). Similar associations were seen on logistic regression if a patient ever smoked; including pneumonia (p < 0.0001), re-intubation (p < 0.0001), and failure to wean (p < 0.0001).
  
  
  
  Smoking tobacco, both current and historical use, leads to an increase in both respiratory and infectious complications. As more centers try to preoperatively condition patients for elective hernia repairs, it is important to note that patients may never return to the baseline outcomes of patients who never smoked.
authors.affiliation: Department of General Surgery, Professional Building, Suite 810, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL, 60612, USA. John_C_Kubasiak@rush.edu.|, 1750 W Harrison St, Jelke Bldg 785, Chicago, IL, 60612, USA. John_C_Kubasiak@rush.edu.
authors.forename: John C
authors.initials: JC
authors.lastname: Kubasiak
authors.affiliation: Department of General Surgery, Professional Building, Suite 810, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL, 60612, USA.
authors.forename: Mackenzie
authors.initials: M
authors.lastname: Landin
authors.affiliation: Department of General Surgery, Professional Building, Suite 810, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL, 60612, USA.
authors.forename: Scott
authors.initials: S
authors.lastname: Schimpke
authors.affiliation: Department of General Surgery, Professional Building, Suite 810, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL, 60612, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Poirier
authors.affiliation: Department of General Surgery, Professional Building, Suite 810, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL, 60612, USA.
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Myers
authors.affiliation: Department of General Surgery, Professional Building, Suite 810, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL, 60612, USA.
authors.forename: Keith W
authors.initials: KW
authors.lastname: Millikan
authors.affiliation: Department of General Surgery, Professional Building, Suite 810, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL, 60612, USA.
authors.forename: Minh B
authors.initials: MB
authors.lastname: Luu
mesh_terms: D000328:Adult; D000787:Angina Pectoris / Q000453:epidemiology; D015897:Comorbidity; D016208:Databases, Factual; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006555:Hernia, Ventral / Q000453:epidemiology / Q000601:surgery*; D059685:Herniorrhaphy / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D010535:Laparoscopy / Q000379:methods; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016491:Peripheral Vascular Diseases / Q000453:epidemiology; D011014:Pneumonia / Q000453:epidemiology*; D011183:Postoperative Complications / Q000453:epidemiology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology*; D013530:Surgical Wound Infection / Q000453:epidemiology; D000073869:Tobacco Smoking; D014481:United States / Q000453:epidemiology
keywords: Incisional hernia; NSQIP; Smoking; Ventral hernia