title: Evaluation of maternal liver elasticity by acoustic radiation force impulse elastosonography in hypertensive disorders of pregnancy: a preliminary descriptive study.
abstract: OBJECTIVE
  To compare maternal liver elasticity scores by Acoustic Radiation Force Impulse (ARFI) elastosonography in healthy and preeclamptic pregnancies and its association with the severity of the disease.
  
  
  METHODS
  Forty-two healthy, 33 mild, 33 severe preeclamptic and 28 pregnant women with Hemolysis, Elevated Liver enzymes and Low Platelets (HELLP) syndrome were included into the study. Maternal liver elasticity was measured by ARFI elastosonography at the first day of puerperium. The maternal and neonatal outcomes of the patients were retrieved from the medical records.
  
  
  RESULTS
  The ARFI-Mean liver elastosonography scores of controls and mild preeclamptic women were lower than severe preeclamptic and HELLP syndrome women (p: 0.001). The mean ARFI elastosonography score >1.22 m/s indicated the effect of severe preeclampsia on maternal liver elasticity with 72.7% sensitivity and 74.7% specificity (Area under curve [AUC], 0.835, 95% confidence interval [CI], 0.757-0.913). The mean ARFI elastosonography score >1.31 m/s indicated the effect of HELLP syndrome on maternal liver elasticity with 78.6% sensitivity and 75.9% specificity (AUC, 0.794, 95% CI, 0.695-0.892).
  
  
  CONCLUSIONS
  The maternal liver becomes stiffer in severe preeclampsia and HELLP syndrome measured by ARFI elastosonography. The increased maternal liver ARFI scores may alert the obstetrician about the possible maternal puerperal morbidity.
authors.affiliation: a Department of Obstetrics and Gynecology , Yuzuncu Yil University , Van , Turkey and.
authors.forename: Orkun
authors.initials: O
authors.lastname: Cetin
authors.affiliation: a Department of Obstetrics and Gynecology , Yuzuncu Yil University , Van , Turkey and.
authors.forename: Erbil
authors.initials: E
authors.lastname: Karaman
authors.affiliation: b Department of Radiology , Faculty of Medicine, Yuzuncu Yil University , Van , Turkey.
authors.forename: Harun
authors.initials: H
authors.lastname: Arslan
authors.affiliation: a Department of Obstetrics and Gynecology , Yuzuncu Yil University , Van , Turkey and.
authors.forename: Ali
authors.initials: A
authors.lastname: Kolusarı
authors.affiliation: a Department of Obstetrics and Gynecology , Yuzuncu Yil University , Van , Turkey and.
authors.forename: Recep
authors.initials: R
authors.lastname: Yıldızhan
authors.affiliation: b Department of Radiology , Faculty of Medicine, Yuzuncu Yil University , Van , Turkey.
authors.forename: Mesut
authors.initials: M
authors.lastname: Ozgokce
authors.affiliation: b Department of Radiology , Faculty of Medicine, Yuzuncu Yil University , Van , Turkey.
authors.forename: Abdussamet
authors.initials: A
authors.lastname: Batur
authors.affiliation: b Department of Radiology , Faculty of Medicine, Yuzuncu Yil University , Van , Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Akbudak
mesh_terms: D000328:Adult; D054459:Elasticity Imaging Techniques; D005260:Female; D017359:HELLP Syndrome / Q000000981:diagnostic imaging*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging*; D011225:Pre-Eclampsia / Q000000981:diagnostic imaging*; D011247:Pregnancy; D055815:Young Adult
keywords: Acoustic Radiation Force Impulse; Pregnancy; elastosonography; maternal liver; preeclampsia