title: Structural and oxidative stabilization of spray dried fish oil microencapsulates with gum arabic and sage polyphenols: Characterization and release kinetics.
abstract: The synergistic efficacy of gum arabic and sage polyphenols in stabilising capsule wall and protecting fish oil encapsulates from heat induced disruption and oxidative deterioration during spray drying was assessed. The emulsions prepared with sodium caseinate as wall polymer, gum arabic as wall co-polymer and sage extract as wall stabiliser was spray dried using a single fluid nozzle. Fish oil encapsulates stabilised with gum arabic and sage extract (SOE) exhibited significantly higher encapsulation efficiency compared to encapsulates containing gum arabic alone (FOE). Scanning electron microscopic and atomic force microscopic images revealed uniform encapsulates with good sphericity and smooth surface for SOE, compared to FOE powder. In vitro oil release of microencapsulates indicated negligible oil release in buffered saline whereas more than 80% of the oil loaded in encapsulates were released in simulated GI fluids. The encapsulates containing sage extract showed a lower rate of lipid oxidation during storage.
authors.affiliation: ICAR-Central Institute of Fisheries Technology (CIFT), Matsyapuri, Willington Island, Cochin 682 029, India. Electronic address: binsipk@yahoo.com.
authors.forename: P K
authors.initials: PK
authors.lastname: Binsi
authors.affiliation: ICAR-Central Institute of Fisheries Technology (CIFT), Matsyapuri, Willington Island, Cochin 682 029, India.
authors.forename: Natasha
authors.initials: N
authors.lastname: Nayak
authors.affiliation: ICAR-Indian Institute of Natural Resins and Gums, Namkum, Ranchi 834 010, India.
authors.forename: P C
authors.initials: PC
authors.lastname: Sarkar
authors.affiliation: ICAR-Mumbai Research Centre of CIFT, Sector-1, Vashi, Navi Mumbai, Maharashtra 400 703, India.
authors.forename: A
authors.initials: A
authors.lastname: Jeyakumari
authors.affiliation: ICAR-Central Institute of Fisheries Technology (CIFT), Matsyapuri, Willington Island, Cochin 682 029, India.
authors.forename: P
authors.initials: P
authors.lastname: Muhamed Ashraf
authors.affiliation: ICAR-Central Institute of Fisheries Technology (CIFT), Matsyapuri, Willington Island, Cochin 682 029, India.
authors.forename: George
authors.initials: G
authors.lastname: Ninan
authors.affiliation: ICAR-Central Institute of Fisheries Technology (CIFT), Matsyapuri, Willington Island, Cochin 682 029, India.
authors.forename: C N
authors.initials: CN
authors.lastname: Ravishankar
mesh_terms: D000818:Animals; D002214:Capsules / Q000737:chemistry; D002364:Caseins / Q000737:chemistry; D004042:Dietary Fats, Unsaturated; D004355:Drug Stability; D004655:Emulsions / Q000737:chemistry; D005395:Fish Oils / Q000008:administration & dosage* / Q000737:chemistry; D006170:Gum Arabic / Q000737:chemistry; D007700:Kinetics; D010084:Oxidation-Reduction; D059808:Polyphenols / Q000737:chemistry; D011208:Powders / Q000737:chemistry; D027543:Salvia officinalis / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D002214:Capsules; D002364:Caseins; D004042:Dietary Fats, Unsaturated; D004655:Emulsions; D005395:Fish Oils; D059808:Polyphenols; D011208:Powders; D006170:Gum Arabic
keywords: Fish oil encapsulates; Oxidation; Polyphenol; Sage extract