title: Bariatric manipulation of gastric arteries: A systematic review on the potential concept for treatment of obesity.
abstract: BACKGROUND
  Gastric artery embolization (GAE) has recently received attention as a minimally invasive intervention in bariatric setting.
  
  
  OBJECTIVE
  The current systematic review aimed to gather and categorizes the existing data in the literature regarding bariatric gastric artery manipulation. This will highlight the importance of this potential concept as a therapeutic modality.
  
  
  METHODS
  A PubMed/Medline search was conducted to identify animal and human studies investigating the effect of gastric artery manipulation on weight, ghrelin, obesity, and tissue adiposity.
  
  
  RESULTS
  A total of 9 studies including 6 animal experiments with 71 subjects and 3 human studies with a total of 25 patients were retrieved. Animal subjects underwent chemical embolization while particle embolization was only used in human subjects. Five animal studies and 1 human study reported decreased ghrelin concentration. Three animal experiments and 2 human studies showed a significant weight change following GAE. There was no report regarding a serious adverse event requiring surgical or interventional management.
  
  
  CONCLUSIONS
  Currently, data regarding the potential role of gastric artery manipulation in decreasing the ghrelin and potential weight loss is scarce.
authors.affiliation: Bariatric and Metabolic Institute, Department of Surgery, The Brooklyn Hospital Center, Icahn School of Medicine at Mount Sinai, Brooklyn, NY, USA.
authors.forename: Saeed
authors.initials: S
authors.lastname: Shoar
authors.affiliation: Bariatric and Metabolic Institute, Department of Surgery, The Brooklyn Hospital Center, Icahn School of Medicine at Mount Sinai, Brooklyn, NY, USA. Electronic address: saber6231@gmail.com.
authors.forename: Alan A
authors.initials: AA
authors.lastname: Saber
authors.affiliation: Faculty of Radiology, Department of Interventional Radiology, The Brooklyn Hospital Center, Icahn School of Medicine at Mount Sinai, Brooklyn, NY, USA.
authors.forename: Mohammaed
authors.initials: M
authors.lastname: Aladdin
authors.affiliation: Faculty of Surgery, Metabolic & Bariatric Surgery Department, Hamad Medical Corporation, Weill Cornell Medical College, Qatar.
authors.forename: Moataz M
authors.initials: MM
authors.lastname: Bashah
authors.affiliation: Faculty of Surgery, Metabolic & Bariatric Surgery Department, Hamad Medical Corporation, Weill Cornell Medical College, Qatar.
authors.forename: Mohammed J
authors.initials: MJ
authors.lastname: AlKuwari
authors.affiliation: Faculty of Surgery, Metabolic & Bariatric Surgery Department, Hamad Medical Corporation, Weill Cornell Medical College, Qatar.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Rizwan
authors.affiliation: Bariatric and Metabolic Institute, Section of Minimally Invasive Surgery, Cleveland Clinic Florida, Weston, FL, USA.
authors.forename: Raul J
authors.initials: RJ
authors.lastname: Rosenthal
mesh_terms: D000273:Adipose Tissue; D000818:Animals; D001158:Arteries; D001835:Body Weight; D004621:Embolization, Therapeutic / Q000379:methods*; D054439:Ghrelin / Q000378:metabolism; D006801:Humans; D009765:Obesity / Q000378:metabolism / Q000628:therapy*; D013270:Stomach / Q000098:blood supply*; D015431:Weight Loss
chemical_list: D054439:Ghrelin
keywords: Bariatric; Gastric artery embolization; Ghrelin; Obesity; Weight loss