title: [Metabolism and cell cycle, two interconnected processes in bacteria].
abstract: To increase chances for a cell to survive in its natural environment, metabolism and cell cycle necessarily have to be interconnected. Indeed, cells need, on the one hand, to check their metabolic status before initiating a cell cycle step often energy-consuming, and, on the other hand, to complete some cell cycle steps before modifying their metabolism. Because bacteria do not differ from the rules, an increasing number of examples of connection between metabolism and cell cycle emerged these last years. Identifying metabolic enzymes as messengers coordinating metabolism and cell cycle allows the addition of another dimension to metabolic maps. Likewise, the very high conservation of these metabolic maps, from bacteria to human, allows inspiring research on tumor cells that are known to have an unrestrained cell cycle and a voracious appetite.
authors.affiliation: Bacterial Cell cycle and Development (BCcD), unité de recherche en biologie des micro-organismes (URBM), université de Namur (UNamur), 61 rue de Bruxelles, 5000 Namur, Belgique.
authors.forename: Régis
authors.initials: R
authors.lastname: Hallez
mesh_terms: D001412:Bacillus subtilis / Q000166:cytology / Q000378:metabolism; D001419:Bacteria / Q000166:cytology* / Q000378:metabolism*; D016935:Caulobacter crescentus / Q000166:cytology* / Q000378:metabolism*; D002453:Cell Cycle / Q000502:physiology*; D004261:DNA Replication; D004269:DNA, Bacterial / Q000096:biosynthesis; D004734:Energy Metabolism; D004926:Escherichia coli / Q000166:cytology / Q000378:metabolism; D006801:Humans; D009369:Neoplasms / Q000473:pathology
chemical_list: D004269:DNA, Bacterial