title: Iron-Catalyzed Synthesis of Sulfur-Containing Heterocycles.
abstract: An iron-catalyzed synthesis of sulfur- and sulfone-containing heterocycles is reported. The method is based on the cyclization of readily available substrates and proceeded with high efficiency and diastereoselectivity. A variety of sulfur-containing heterocycles bearing moieties suitable for subsequent functionalization are prepared. Illustrative examples of such postcyclization modifications are also presented.
authors.affiliation: Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI)-UMR 8231, ESPCI Paris, CNRS, PSL Research University , 10 rue Vauquelin 75231 Paris Cedex 05, France.
authors.forename: Cyril
authors.initials: C
authors.lastname: Bosset
authors.affiliation: Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI)-UMR 8231, ESPCI Paris, CNRS, PSL Research University , 10 rue Vauquelin 75231 Paris Cedex 05, France.
authors.forename: Gauthier
authors.initials: G
authors.lastname: Lefebvre
authors.affiliation: Janssen Research & Development, Oncology Discovery Chemistry, Campus de Maigremont CS 10615 , 27106 Cedex, Val de Reuil, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Angibaud
authors.affiliation: Janssen Research & Development, Oncology Discovery Chemistry, Campus de Maigremont CS 10615 , 27106 Cedex, Val de Reuil, France.
authors.forename: Ian
authors.initials: I
authors.lastname: Stansfield
authors.affiliation: Janssen Research & Development, Janssen Pharmaceutica NV Turnhoutseweg 30, 2340 Beerse, Belgium.
authors.forename: Lieven
authors.initials: L
authors.lastname: Meerpoel
authors.affiliation: Janssen Research & Development, Oncology Discovery Chemistry, Campus de Maigremont CS 10615 , 27106 Cedex, Val de Reuil, France.
authors.forename: Didier
authors.initials: D
authors.lastname: Berthelot
authors.affiliation: Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI)-UMR 8231, ESPCI Paris, CNRS, PSL Research University , 10 rue Vauquelin 75231 Paris Cedex 05, France.
authors.forename: Amandine
authors.initials: A
authors.lastname: Guérinot
authors.affiliation: Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI)-UMR 8231, ESPCI Paris, CNRS, PSL Research University , 10 rue Vauquelin 75231 Paris Cedex 05, France.
authors.forename: Janine
authors.initials: J
authors.lastname: Cossy