title: Comparison of FNAC smears, cytospin smears, and cellblocks of transthoracic guided FNAC of suspected lung tumor: A study of 100 cases.
abstract: BACKGROUND
  Transthoracic guided fine needle aspiration cytology (FNAC) of clinically suspected lung tumors is an increasingly common procedure in diagnosis. Cytospin Smear and Cellblock preparations of available material are helpful in subtyping and confirming the diagnosis, and they can also be used for further studies, i.e., special stain and immunohistochemistry, etc.
  
  
  OBJECTIVE
  This research was undertaken to study the technique of guided transthoracic lung FNAC of clinically suspected lung tumors and the establish role of FNAC smears, cytospin smears, and cellblocks in the detection and typing of neoplastic lung lesions and correlation.
  
  
  METHODS
  Guided FNAC was taken from 100 cases of clinically suspected lung tumor and FNAC smears, cytospin smears, and cellblocks of aspirated material were studied over a period of 2 years from September 2011 to September 2013.
  
  
  RESULTS
  The material adequacies were 80% in FNAC smears, 83% in cytospin smears, and 89% in cellblocks. Additional information supported by cytospin smear and cellblock was 3% and 9%, respectively. Architectural preservation was better in FNAC smears (85%) and cellblocks (73.03%) than that in cytospin smears (31.33%). Morphological preservation was better in FNAC smears (90%) and cellblocks (75.28%) than that in cytospin smears (14.46%). Diagnostic accuracy was increased in the cellblocks and cytospin smears.
  
  
  CONCLUSIONS
  Cytospin smear was helpful when low cellular material was obtained, and the concomitant examination of cellblocks not only confirmed the diagnosis of malignancy but also helped in classifying the obtained material and allowed further study on the same.
authors.affiliation: Department of Pathology, MP Shah Government Medical College, Guru Govind Singh Government Hospital, Jamnagar, Gujarat, India.
authors.forename: Ankur Singh
authors.initials: AS
authors.lastname: Kshatriya
authors.affiliation: Department of Pathology, MP Shah Government Medical College, Guru Govind Singh Government Hospital, Jamnagar, Gujarat, India.
authors.forename: Pravina M
authors.initials: PM
authors.lastname: Santwani
keywords: Cellblock; cellblocks; cytospin; cytospin smear; lung tumors; transthoracic fine-needle aspiration cytology (FNAC); transthoracic lung FNAC