title: Calgary score and modified Calgary score in the differential diagnosis between neurally mediated syncope and epilepsy in children.
abstract: To evaluate the value of Calgary score and modified Calgary score in differential diagnosis between neurally mediated syncope and epilepsy in children. 201 children experienced one or more episodes of loss of consciousness and diagnosed as neurally mediated syncope or epilepsy were enrolled. Calgary score, modified Calgary score and receiver-operating characteristic curve were used to explore the predictive value in differential diagnosis. There were significant differences in median Calgary score between syncope [-4.00 (-6, 1)] and epilepsy [2 (-3, 5)] (z = -11.63, P < 0.01). When Calgary score ≥1, the sensitivity and specificity of differential diagnosis between syncope and epilepsy were 91.46 and 95.80 %, suggesting a diagnosis of epilepsy. There were significant differences in median modified Calgary score between syncope [-4.00 (-6, 1)] and epilepsy [3 (-3, 6)] (z = -11.71, P < 0.01). When modified Calgary score ≥1, the sensitivity and specificity were 92.68 and 96.64 %, suggesting a diagnosis of epilepsy. The sensitivity and specificity of modified Calgary score and Calgary score did not show significant differences (P > 0.05). Calgary score and modified Calgary score could be used to differential diagnosis between syncope and epilepsy in children.
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China.
authors.forename: Runmei
authors.initials: R
authors.lastname: Zou
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China.
authors.forename: Shuo
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Zhu
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China.
authors.forename: Lijia
authors.initials: L
authors.lastname: Wu
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Lin
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China.
authors.forename: Zhenwu
authors.initials: Z
authors.lastname: Xie
authors.affiliation: Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Changsha, 410011, Hunan, China. wangcheng2nd@126.com.
authors.forename: Cheng
authors.initials: C
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D001794:Blood Pressure / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D056152:Respiratory Rate / Q000502:physiology; D012680:Sensitivity and Specificity; D013575:Syncope / Q000175:diagnosis* / Q000503:physiopathology; D018667:Tilt-Table Test
keywords: Calgary score; Epilepsy; Neurally mediated syncope; Seizures