title: The Use of Routine Blood Cultures in Pediatric Appendicitis.
abstract: OBJECTIVE
  To determine the proportion of true-positive blood culture results in children presenting to the ED with suspected appendicitis. To describe the current practice of obtaining blood cultures in children with suspected appendicitis.
  
  
  METHODS
  We performed a 2-year retrospective health record review of all children aged 2 through 17 years investigated for suspected appendicitis at a tertiary Pediatric Emergency Department. Subjects were identified by searching (a) institutional records for ICD-10-CA coding, (b) diagnostic imaging records of ultrasounds for appendicitis, and (c) surgical database records for nonincidental appendectomies. Abstracted demographic and clinical data were matched to regional laboratory services data to describe the performance and result of blood cultures.
  
  
  RESULTS
  Overall, 1315 children investigated for appendicitis were reviewed. Seven hundred fifty (57.0%) were girls, the average age was 11.7 years (SD, 4.0). Blood cultures were obtained in 288 (21.9%) of 1315 patients. Of the 11 (3.8%) cultures that were positive, only 1 (0.35%) was a true positive. Young age, high triage acuity, and presence of fever were associated with the acquisition of cultures (P < 0.001 for all). The proportion of children undergoing appendectomy and the negative appendectomy rate was similar between those with and without blood culture (P = 0.10 and P = 0.96, respectively).
  
  
  CONCLUSIONS
  True-positive blood cultures are very rare in children presenting to the ED with suspected appendicitis. Given the potential for false-positive cultures and the social/economic implications of initial testing/retesting of false positives, the use of routine blood cultures for children with suspected appendicitis is not supported.
authors.forename: Graham Cameron
authors.initials: GC
authors.lastname: Thompson
authors.forename: Ellen
authors.initials: E
authors.lastname: Morrison
authors.forename: Marshall
authors.initials: M
authors.lastname: Ross
authors.forename: Helena
authors.initials: H
authors.lastname: Liu
authors.forename: Otto G
authors.initials: OG
authors.lastname: Vanderkooi
authors.forename: Robin
authors.initials: R
authors.lastname: Eccles
mesh_terms: D000293:Adolescent; D001062:Appendectomy / Q000706:statistics & numerical data; D001064:Appendicitis / Q000175:diagnosis* / Q000601:surgery; D000071997:Blood Culture / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies