title: Experts Opinion on the Practical Use of Azathioprine and 6-Mercaptopurine in Inflammatory Bowel Disease.
abstract: The relevance of azathioprine and 6-mercaptopurine therapy in inflammatory bowel disease, Crohn's disease, and ulcerative colitis, has been challenged in recent publications. In this article, a panel of experts gives advice, based on the relevant literature, on indications and practical use of azathioprine/6-mercaptopurine, prevention, and management of drug adverse reactions and special situations such as vaccination, pregnancy, and lactation.
authors.affiliation: *Division of Gastroenterology, Hôpital Neuchâtelois, Neuchâtel, Switzerland;†Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland;‡Division of Gastroenterology Clinic for Visceral Surgery and Medicine, Inselspital Bern, Bern, Switzerland;§Division of Gastroenterology and Hepxatology, Saint-Antoine Hospital, Pierre et Marie Curie-Paris 6 University, Paris, France;‖Division of Gastroenterology, University Hospital of Basel, Basel, Switzerland;¶Division of Gastroenterology and Hepatology, Ospedale Regionale di Lugano, Lugano, Switzerland;**Division of Gastroenterology and Hepatology, Lindenhofspital Bern, Bern, Switzerland;††Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland;‡‡Division of Gastroenterology and Hepatology, Stadtspital Triemli, Zurich, Switzerland; and§§Crohn and Colitis Centre, Clinique La Source-Beaulieu, Lausanne, Switzerland.
authors.forename: Christian
authors.initials: C
authors.lastname: Mottet
authors.forename: Alain M
authors.initials: AM
authors.lastname: Schoepfer
authors.forename: Pascal
authors.initials: P
authors.lastname: Juillerat
authors.forename: Jacques
authors.initials: J
authors.lastname: Cosnes
authors.forename: Florian
authors.initials: F
authors.lastname: Froehlich
authors.forename: Vera
authors.initials: V
authors.lastname: Kessler-Brondolo
authors.forename: Frank
authors.initials: F
authors.lastname: Seibold
authors.forename: Gerhard
authors.initials: G
authors.lastname: Rogler
authors.forename: Stephan R
authors.initials: SR
authors.lastname: Vavricka
authors.forename: Pierre
authors.initials: P
authors.lastname: Michetti
mesh_terms: D001379:Azathioprine / Q000627:therapeutic use*; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003424:Crohn Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D015122:Mercaptopurine / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D011247:Pregnancy
chemical_list: D007166:Immunosuppressive Agents; D015122:Mercaptopurine; D001379:Azathioprine