title: The Management of Hepatitis B in Liver Transplant Recipients.
abstract: Liver transplant (LT) is now an established indication for patients with chronic hepatitis B, mainly because of the development and use of hepatitis B immunoglobulin (HBIG) and oral antivirals for prophylaxis. The combination of low-dose HBIG and antivirals has been considered the standard prophylaxis regimen to prevent post-LT recurrence of hepatitis B. The important remaining issues are related to the long-term cost of HBIG and the risk of escape hepatitis B virus (HBV) mutants. Strategies for prevention of HBV after LT are constantly improving. With the availability of new nucleoside/nucleotide analogues, new post-LT strategies also should emerge.
authors.affiliation: Department of Surgery, University of California at Los Angeles, Los Angeles, CA, USA; Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. Electronic address: SSaab@mednet.ucla.edu.
authors.forename: Sammy
authors.initials: S
authors.lastname: Saab
authors.affiliation: Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
authors.forename: Ping-Yu
authors.initials: PY
authors.lastname: Chen
authors.affiliation: Department of Surgery, University of California at Los Angeles, Los Angeles, CA, USA.
authors.forename: Clara E
authors.initials: CE
authors.lastname: Saab
authors.affiliation: Department of Surgery, University of California at Los Angeles, Los Angeles, CA, USA; Huntington Medical Research Institutes, Pasadena, CA, USA.
authors.forename: Myron J
authors.initials: MJ
authors.lastname: Tong
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D019468:Disease Management; D014943:Global Health; D006509:Hepatitis B / Q000188:drug therapy / Q000453:epidemiology / Q000821:virology; D006515:Hepatitis B virus; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation; D066027:Transplant Recipients
chemical_list: D000998:Antiviral Agents
keywords: Antiviral therapy; Cirrhosis; Hepatitis B; Liver transplant