title: Vestibular implants studied in animal models: clinical and scientific implications.
abstract: Damage to the peripheral vestibular system can result in debilitating postural, perceptual, and visual symptoms. A potential new treatment for this clinical problem is to replace some aspects of peripheral vestibular function with an implant that senses head motion and provides this information to the brain by stimulating branches of the vestibular nerve. In this review I consider animal studies performed at our institution over the past 15 years, which have helped elucidate how the brain processes information provided by a vestibular (semicircular canal) implant and how this information could be used to improve the problems experienced by patients with peripheral vestibular damage.
authors.affiliation: Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts; richard_lewis@meei.harvard.edu.|Department of Neurology, Harvard Medical School, Boston, Massachusetts; and.|Jenks Vestibular Physiology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts.
authors.forename: Richard F
authors.initials: RF
authors.lastname: Lewis
mesh_terms: D000818:Animals; D003054:Cochlear Implants; D004195:Disease Models, Animal; D004558:Electric Stimulation; D006801:Humans; D010465:Perception / Q000502:physiology; D004856:Postural Balance / Q000502:physiology; D015837:Vestibular Diseases / Q000503:physiopathology* / Q000601:surgery*
keywords: ataxia; implant; prosthesis; vertigo; vestibular system