title: The comparison between the serum level of interleukin-6 in women with acute ovarian torsion and other causes of lower abdominal pain.
abstract: The aim of this study was to investigate the role of serum Interleukin-6 (IL-6) as a predictive value to make decision for surgical interventions when ovarian torsion (OT) is suspected. This study was performed on 284 women with lower abdominal pain. IL-6 levels were compared between OT (n = 67, 23.6%) and control groups (n = 217, 76.4%). For the purpose of diagnosis of OT, sensitivity and specificity of IL-6 at the cut-off point of 9.6 pg/ml were 41.79 and 82.49%, respectively. Patients with ovarian masses on ultrasound and IL-6 >9.6 pg/ml were found to be 24 times more likely to develop OT. Patients with serum IL-6 >9.6 pg/ml who lacked blood flow in ovarian Doppler ultrasound had 40.75 times higher risk of developing OT. It seems that simultaneous use of Doppler ultrasound and serum IL-6 levels can be helpful for early diagnosis of OT and making decision for surgical intervention.
authors.affiliation: a Department of Obstetrics and Gynaecology , Kermanshah University of Medical Sciences, Imam Reza hospital , Kermanshah , Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Zangene
authors.affiliation: a Department of Obstetrics and Gynaecology , Kermanshah University of Medical Sciences, Imam Reza hospital , Kermanshah , Iran.
authors.forename: Atefeh
authors.initials: A
authors.lastname: Ashoori Barmchi
authors.affiliation: b Department of Biostatistics and Epidemiology , Kermanshah University of Medical Sciences , Kermanshah , Iran.
authors.forename: Mansour
authors.initials: M
authors.lastname: Rezaei
authors.affiliation: a Department of Obstetrics and Gynaecology , Kermanshah University of Medical Sciences, Imam Reza hospital , Kermanshah , Iran.
authors.forename: Firoozeh
authors.initials: F
authors.lastname: Veisi
mesh_terms: D015746:Abdominal Pain / Q000097:blood* / Q000175:diagnosis / Q000209:etiology; D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D010049:Ovarian Diseases / Q000097:blood* / Q000175:diagnosis; D010053:Ovary / Q000000981:diagnostic imaging / Q000473:pathology*; D012372:ROC Curve; D012680:Sensitivity and Specificity; D014102:Torsion Abnormality / Q000097:blood* / Q000175:diagnosis; D018608:Ultrasonography, Doppler; D055815:Young Adult
chemical_list: D015415:Biomarkers; D015850:Interleukin-6
keywords: Ovarian torsion; abdominal pain; interleukin-6