title: A case of severe pyruvate kinase deficiency in a primigravida: successful outcome.
abstract: Pyruvate kinase deficiency (PKD) is a rare non-spherocytic type of haemolytic anaemia. During pregnancy, women with severe PKD are at increased risk of infection, thrombosis, hypertension, fetal growth restriction and anaemia. Management of such cases requires close collaboration between a haematologist and an obstetrician. We report a case of severe PKD in pregnancy with good maternal and fetal outcome.
authors.affiliation: Obstetrics & Gynaecology, Queen's Hospital, Rom Valley Way, Romford, Essex, RM7 0AG.
authors.forename: Sahar
authors.initials: S
authors.lastname: Mohamed
authors.affiliation: Obstetrics & Gynaecology, Queen's Hospital, Rom Valley Way, Romford, Essex, RM7 0AG.
authors.forename: Kenga
authors.initials: K
authors.lastname: Sivarajah
authors.affiliation: Consultant Obstetrician, Queen's Hospital, Rom Valley Way, Romford, Essex, RM7 0AG.
authors.forename: Seema
authors.initials: S
authors.lastname: Chakravarti
keywords: haematology; high-risk pregnancy; maternal-fetal medicine