title: Imaging Evaluation and Relative Significance in Cases of Cervical Disk Allografting: Radiographic Character After Total Disk Transplantation.
abstract: The clinical and radiologic data of total disk allografting (TDA) cases were collected and analyzed to explore the correlation between neurological function improvements and imaging changes.
  
  
  
  The aim of the study was to assess the medium-term and long-term outcome and radiographic character after TDA, and, furthermore, to explore the significance of the changes of imaging signs after the transplantation.
  
  
  
  Spinal fusion may result in the adjacent segment degeneration. The anxiousness urged the necessity for the development of TDA to reduce the risk of adjacent segment degeneration. Both animal studies and recent clinical trials have shown promising results to support the use of intervertebral disk allograft as a natural mobile disk replacement.
  
  
  
  The conditions of 13 cases that underwent TDA after cervical discectomy were recorded in detail. Axial symptoms and neurological function in various periods were assessed, and, meanwhile, radiologic examination was performed for the comprehensive evaluation of the relevant indicators before and after surgery.
  
  
  
  (1) There was significant improvement in the neurological function after TDA. Postoperatively, the Visual Analog Score of axial symptoms did not increase significantly. (2) Both the entire and local segment maintained a satisfactory curve after allografting. There was no obvious correlation between the neurological function recovery and the cervical curve. Besides, the motion of the cervical spine did not change postoperatively. (3) Postoperatively, the spinal cord area at the index level increased significantly, whereas the signal value of the transplanted disk decreased sharply.
  
  
  
  (1) Disk allografting is one of the effective and safe methods in treating the diseases of cervical disk herniation. (2) Although some degeneration occurs in the transplanted disk, the allograft can still be alive and can successfully maintain and improve the biological characters of the cervical spine in both radiologic and practical aspects.
authors.affiliation: *Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an †Department of Orthopaedics, Navy General Hospital, Beijing, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Ding
authors.forename: Di-Ke
authors.initials: DK
authors.lastname: Ruan
authors.forename: Qing
authors.initials: Q
authors.lastname: He
authors.forename: Li Sheng
authors.initials: LS
authors.lastname: Hou
authors.forename: Jian Ning
authors.initials: JN
authors.lastname: Lin
authors.forename: Hong Peng
authors.initials: HP
authors.lastname: Cui
mesh_terms: D000328:Adult; D002574:Cervical Vertebrae / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000000981:diagnostic imaging* / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D010147:Pain Measurement; D011859:Radiography; D016059:Range of Motion, Articular; D013123:Spinal Fusion / Q000379:methods*; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed; D059145:Total Disc Replacement / Q000379:methods*; D014184:Transplantation, Homologous / Q000379:methods; D016896:Treatment Outcome