title: Macular Choroidal Thickness in Myopic Eyes with and without a Dome-Shaped Macula: A Case-Control Study.
abstract: OBJECTIVE
  Dome-shaped macula (DSM) has recently been described with myopic staphyloma, which may cause decreased vision. The purpose of this study was to evaluate the choroidal thickness of eyes with and eyes without DSM.
  
  
  METHODS
  A total of 26 eyes with DSM were paired based on axial length with 26 eyes without DSM. All patients underwent spectral-domain OCT examination using the 7-line EDI (enhanced depth imaging) protocol. The mean choroidal thickness was measured using Early Treatment Diabetic Retinopathy Study (ETDRS) grid areas.
  
  
  RESULTS
  Both nasal choroidal thickness and temporal choroidal thickness were significantly thinner in the DSM group (120.43 vs. 159.46 µm, p = 0.035, and 142.17 vs. 187.23 µm, p = 0.021, respectively). However, the mean central choroidal thickness did not differ (152.61 vs. 175.96 µm, p = 0.20). The ratio between central and peripheral choroidal thickness was very significantly elevated with DSM (1.18 ± 0.12 vs. 0.99 ± 0.09, p < 0.0001).
  
  
  CONCLUSIONS
  Choroidal thickness decreases at the periphery but not in the macular area with DSM. DSM seems not to be due to an inward protrusion of the globe but due to macular anatomical preservation in a growing staphyloma.
authors.affiliation: Hopitaux universitaires de Strasbourg, Strasbourg, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Soudier
authors.forename: Alain
authors.initials: A
authors.lastname: Gaudric
authors.forename: Vincent
authors.initials: V
authors.lastname: Gualino
authors.forename: Pascale
authors.initials: P
authors.lastname: Massin
authors.forename: Mathieu
authors.initials: M
authors.lastname: Nardin
authors.forename: Ramin
authors.initials: R
authors.lastname: Tadayoni
authors.forename: Claude
authors.initials: C
authors.lastname: Speeg-Schatz
authors.forename: David
authors.initials: D
authors.lastname: Gaucher
mesh_terms: D016022:Case-Control Studies; D002829:Choroid / Q000000981:diagnostic imaging*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000000981:diagnostic imaging*; D008297:Male; D047728:Myopia, Degenerative / Q000175:diagnosis* / Q000503:physiopathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity