title: Influence of Hormonal Changes on Audiologic Examination in Normal Ovarian Cycle Females: An Analytic Study.
abstract: IntroductionThere is only limited information from previous studies that suggest that auditory function may be influenced by hormones. Recent advances in the field have exposed the potential role of hormones in modulating the auditory system.ObjectiveThis study aims to investigate the relationship between menstrual cycle and outer hair cell function with audiological examination.MethodsThis is an analytic study with a cross-sectional design. The sampling was a systematic random sampling. We found 49 women with normal menstrual cycle and collected their data through interviews, physical examination, and examination of the ear, with otoscopic and other routine otorhinolaryngology examinations. We evaluated Tympanometry, distortion-product otoacoustic emissions (DPOAE), and pure tone audiometry.ResultsWe found the audiometric threshold worse in the follicular phase than other phases at 4000 Hz of the right ear, and in the ovulation was found best than any other phases at 1000 Hz of the left ear with significant difference. We found significant difference of DPOAE between ovulation time and follicular phase at 3000 Hz and 1000 Hz in the left ear and between ovulation and luteal phased at 2000 Hz, 3000 Hz and 5000 Hz in the right ear and at 1000 Hz in the left ear withp< 0.05.ConclusionThe result of this study showed that only a small part of audiometry threshold had a significant difference between each menstrual phase. In other words, we found no correlation between menstrual and audiometry threshold. Nonetheless, there is a correlation between menstrual cycle phase and DPOAE amplitude.
authors.affiliation: Department of Otorhinolaryngology, Universitas Sumatera Utara, Medan, North Sumatera, Indonesia.
authors.forename: Indri
authors.initials: I
authors.lastname: Adriztina
authors.affiliation: Department of Otorhinolaryngology, Universitas Sumatera Utara, Medan, North Sumatera, Indonesia.
authors.forename: Adlin
authors.initials: A
authors.lastname: Adnan
authors.affiliation: Department of Obstetrics and Gynecology, Universitas Sumatera Utara, Medan, North Sumatera, Indonesia.
authors.forename: Ichwanul
authors.initials: I
authors.lastname: Adenin
authors.affiliation: Department of Otorhinolaryngology, Universitas Sumatera Utara, Medan, North Sumatera, Indonesia.
authors.forename: Siti Hajar
authors.initials: SH
authors.lastname: Haryuna
authors.affiliation: Department of Epidemiology training research advocacy and teaching, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia.
authors.forename: Sorimuda
authors.initials: S
authors.lastname: Sarumpaet
keywords: DPOAE; follicular phase; luteal phase; menstrual cycle; ovulation