title: PKA Has the Gall to Oppose NLRP3.
abstract: The involvement of the NLRP3 inflammasome in inflammatory diseases has generated interest in identifying endogenous mechanisms that inhibit NLRP3. In this issue of Immunity, Guo et al. (2016) reveal bile acids as negative regulators of the NLRP3 inflammasome.
authors.affiliation: Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany.
authors.forename: Christina J
authors.initials: CJ
authors.lastname: Groß
authors.affiliation: Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany. Electronic address: olaf.gross@tum.de.
authors.forename: Olaf
authors.initials: O
authors.lastname: Groß
mesh_terms: D000818:Animals; D006801:Humans; D017868:Cyclic AMP-Dependent Protein Kinases / Q000276:immunology / Q000378:metabolism; D058847:Inflammasomes / Q000276:immunology / Q000378:metabolism; D007249:Inflammation / Q000276:immunology / Q000378:metabolism; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein / Q000276:immunology / Q000378:metabolism
chemical_list: D017868:Cyclic AMP-Dependent Protein Kinases; D058847:Inflammasomes; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein