title: Primary pulmonary angiosarcoma: Three case reports and literature review.
abstract: Primary pulmonary angiosarcoma is a rare type of malignant vascular tumor with a very aggressive clinical course and a grim prognosis. To date, only a handful of cases have been reported in English literature. Its rarity and consequent low index of suspicion makes clinical diagnosis difficult. In this report we present three cases of primary pulmonary angiosarcoma with cough, hemoptysis, and progressive dyspnea to contribute to the sparse literature on this disease. A review is made of previous reports of primary pulmonary angiosarcomas, and the clinical characteristics, diagnosed method, treatment options, and prognosis of pulmonary angiosarcoma are also discussed.
authors.affiliation: Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.|Department of Respiratory Medicine, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Beijing, China.
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Ren
authors.affiliation: Department of Respiratory Medicine, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Beijing, China.|Department of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhu
authors.affiliation: Department of Respiratory Medicine, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Beijing, China.|Department of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Respiratory Medicine, Capital Medical University, Beijing, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Diao
authors.affiliation: Department of Respiratory Medicine, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Beijing, China.|Department of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
authors.forename: Yuhui
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D019468:Disease Management; D017809:Fatal Outcome; D005260:Female; D006394:Hemangiosarcoma / Q000000981:diagnostic imaging*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Angiosarcoma; biopsy; immunohistochemistry