title: [Medico-economic evaluation of therapeutic strategies at hospital: A systematic review of French studies].
abstract: BACKGROUND
  Therapeutic innovation contributes to the increase of health care expenditures in France. Medico-economic evaluation has still a minor role in the decision-making for the registration of drugs and medical devices in hospitals. This study aimed to systematically review published works on medico-economic studies conducted within French hospitals.
  
  
  METHODS
  A literature review was carried out to search for medico-economic studies conducted by hospital teams on therapeutic or diagnostic strategies employed within French hospitals and published from 2010 to 2014. Quality assessment of selected studies was performed according to Drummond et al.'s checklist, which is also used within French guidelines.
  
  
  RESULTS
  Of the 44 analyzed articles, methods for identification and measure of costs and results complied with guidelines in 95 % of cases. For results interpretation, compliance was 91 %. Costs discounting (29 %) and the use of sensitivity analysis to account for results uncertainty (70 %) were the parameters with the lowest compliance to guidelines.
  
  
  CONCLUSIONS
  A good training of health professionals in using economic and statistic tools, and the transferability of results of medico-economic studies are essential and should be optimized to enable a broader use of medico-economic evaluation within the scope of decision-making in French hospitals.
authors.affiliation: Service pharmacie, hôpital d'instruction des armées Desgenettes, 108, boulevard Pinel, 69275 Lyon, France. Electronic address: int.amandine.baudouin@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Baudouin
authors.affiliation: Hospices civils de Lyon, délégation à la recherche clinique et à l'innovation, cellule innovation, Lyon/UMR CNRS 5510 Mateis, 59, boulevard Pinel, 69677 Bron cedex, France; Division of Health Sciences, Warwick Medical School, the University of Warwick, Coventry CV4 7AL, Royaume-Uni.
authors.forename: X
authors.initials: X
authors.lastname: Armoiry
authors.affiliation: Service pharmacie, hôpital d'instruction des armées Desgenettes, 108, boulevard Pinel, 69275 Lyon, France; Laboratoire parcours santé systémique, EAM 4129, université Claude-Bernard Lyon 1, quai des Célestins, 69002 Lyon, France.
authors.forename: C
authors.initials: C
authors.lastname: Dussart
mesh_terms: D003362:Cost-Benefit Analysis; D003933:Diagnosis; D004469:Economics, Hospital; D005602:France; D005102:Health Expenditures / Q000706:statistics & numerical data*; D006801:Humans
keywords: Drug evaluation; Hospital economics; Referencing; Référencement; Économie hospitalière; Évaluation de médicament