title: Absorption of bovine angiogenin into peripheral blood of rats orally administered milk basic protein.
abstract: Bovine angiogenin is a major component of the bone resorption inhibitory activity of milk basic protein (MBP). The intestinal absorption of bovine angiogenin was investigated in a rat model, where it was detected in an intact form in the peripheral blood after the oral administration of MBP. This finding demonstrates that orally administered bovine angiogenin is absorbed without being degraded.
authors.affiliation: a Milk Science Research Institute, Megmilk Snow Brand Co., Ltd , Kawagoe , Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Ishida
authors.affiliation: a Milk Science Research Institute, Megmilk Snow Brand Co., Ltd , Kawagoe , Japan.
authors.forename: Takehiko
authors.initials: T
authors.lastname: Yasueda
authors.affiliation: a Milk Science Research Institute, Megmilk Snow Brand Co., Ltd , Kawagoe , Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Murakami
authors.affiliation: a Milk Science Research Institute, Megmilk Snow Brand Co., Ltd , Kawagoe , Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Kato
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002417:Cattle; D007408:Intestinal Absorption; D008297:Male; D008894:Milk Proteins / Q000008:administration & dosage* / Q000493:pharmacokinetics; D017207:Rats, Sprague-Dawley; D012259:Ribonuclease, Pancreatic / Q000097:blood* / Q000493:pharmacokinetics*
chemical_list: D008894:Milk Proteins; C046366:angiogenin; D012259:Ribonuclease, Pancreatic
keywords: MBP; absorption; angiogenin; bone metabolism; milk basic protein