title: Transient arterial phase respiratory motion-related artifact in MR imaging of the liver: an analysis of four different gadolinium-based contrast agents.
abstract: OBJECTIVE
  The purpose was to compare hepatic arterial phase (HAP) respiratory motion artifact (RMA) between gadoxetate, gadobutrol, gadopentetate, and gadobenate.
  
  
  METHODS
  Two hundred cases of each gadolinium agent were included. RMA was assigned using 5-point Likert scale (1=no motion, 5=extreme motion) on precontrast and HAP. RMA increase (increase ≥1 on HAP from precontrast) was the outcome in logistic regression.
  
  
  RESULTS
  Odds of RMA increase for gadoxetate were 5.5 (P<.001), 3.6 (P=.034), and 9.5 (P<.001) times higher than gadobutrol, gadopentetate, and gadobenate, respectively. Gadolinium volume and dose were not independent predictors of RMA increase.
  
  
  CONCLUSIONS
  Gadoxetate has increased odds of RMA compared with other gadolinium agents; tight contrast bolus is not a contributor.
authors.affiliation: Department of Radiology, Montefiore Medical Center, 111 E 210th St., Bronx, NY 10467.
authors.forename: Mansi R
authors.initials: MR
authors.lastname: Shah
authors.affiliation: Department of Radiology, Montefiore Medical Center, 111 E 210th St., Bronx, NY 10467. Electronic address: mflusberg@gmail.com.
authors.forename: Milana
authors.initials: M
authors.lastname: Flusberg
authors.affiliation: Department of Radiology, Montefiore Medical Center, 111 E 210th St., Bronx, NY 10467.
authors.forename: Viktoriya
authors.initials: V
authors.lastname: Paroder
authors.affiliation: Department of Radiology, Montefiore Medical Center, 111 E 210th St., Bronx, NY 10467.
authors.forename: Alla M
authors.initials: AM
authors.lastname: Rozenblit
authors.affiliation: Department of Radiology, Montefiore Medical Center, 111 E 210th St., Bronx, NY 10467.
authors.forename: Victoria
authors.initials: V
authors.lastname: Chernyak
mesh_terms: D016477:Artifacts; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006499:Hepatic Artery; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging*; D008107:Liver Diseases / Q000000981:diagnostic imaging; D016015:Logistic Models; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives; D008875:Middle Aged; D009038:Motion; D009942:Organometallic Compounds; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C073590:gadolinium ethoxybenzyl DTPA; C064572:gadobenic acid; C090600:gadobutrol; D008536:Meglumine; D005682:Gadolinium; D019786:Gadolinium DTPA
keywords: Gadoxetate; Hepatic arterial phase; Respiratory motion artifact; Transient respiratory motion