title: Immunohistochemical expression of vascular endothelial growth factor in orofacial lesions - A review.
abstract: Angiogenesis is considered to be an important biological process in disease progression and tumorigenesis. Among the various factors associated with angiogenesis, vascular endothelial growth factor (VEGF) is a leading candidate. VEGF induces the proliferation, differentiation, and migration of vascular endothelial cells, increases capillary permeability, and enhances endothelial cell survival by preventing apoptosis. This article reviews and highlights the role of VEGF in health, and various oral diseases.
authors.affiliation: Senior Lecturer, Department of Oral Pathology, Rama Dental College, Kanpur, U.P., India.
authors.forename: Bhavana
authors.initials: B
authors.lastname: Gupta
authors.affiliation: Professor and Head, Department of Oral Pathology, King George's Medical University, Lucknow, India.
authors.forename: Shaleen
authors.initials: S
authors.lastname: Chandra
authors.affiliation: Associate Professor, Department of Oral Pathology, Chandra Dental College, Lucknow, U.P., India.
authors.forename: Vineet
authors.initials: V
authors.lastname: Raj
authors.affiliation: Professor, Department of Periodontology, Rama Dental College and Hospital, Kanpur, India.
authors.forename: Vivek
authors.initials: V
authors.lastname: Gupta
keywords: Angiogenesis; Oral cancer; Oral diseases; Oral squamous cell carcinoma (OSCC); Vascular endothelial growth factor (VEGF)