title: Identification of a potential topoisomerase II "hotspot" DNA region in the DEK gene in two t(6;9)-positive therapy-related myeloid neoplasms.
authors.affiliation: Laboratory of Neuro-Oncoematology, Santa Lucia Foundation, Rome, Italy.|Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy.
authors.forename: Maria Liliana
authors.initials: ML
authors.lastname: Piredda
authors.affiliation: Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy.
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Catalano
authors.affiliation: Policlinico di tor Vergata, Rome, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Ciardi
authors.affiliation: Policlinico di tor Vergata, Rome, Italy.
authors.forename: Mariadomenica
authors.initials: M
authors.lastname: Divona
authors.affiliation: Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Cicconi
authors.affiliation: Policlinico di tor Vergata, Rome, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Panetta
authors.affiliation: Policlinico di tor Vergata, Rome, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Curzi
authors.affiliation: Laboratory of Neuro-Oncoematology, Santa Lucia Foundation, Rome, Italy.|Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy.|Laboratorios Dr. Moreira, Monterrey, Mexico.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Garza
authors.affiliation: Laboratory of Neuro-Oncoematology, Santa Lucia Foundation, Rome, Italy.|Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy.|Alfonso Martin Escudero Foundation, Madrid, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Martínez-Losada
authors.affiliation: Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Postorino
authors.affiliation: Laboratory of Neuro-Oncoematology, Santa Lucia Foundation, Rome, Italy.|Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Lo-Coco
authors.affiliation: Laboratory of Neuro-Oncoematology, Santa Lucia Foundation, Rome, Italy. nelnoguera@yahoo.com.ar.|Department of Biomedicine, "Tor Vergata" University, Via Montpellier 1, 00133, Rome, Italy. nelnoguera@yahoo.com.ar.
authors.forename: Nélida I
authors.initials: NI
authors.lastname: Noguera
mesh_terms: D001483:Base Sequence; D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics*; D004250:DNA Topoisomerases, Type II / Q000235:genetics*; D019008:Drug Resistance, Neoplasm; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000139:chemically induced / Q000188:drug therapy / Q000235:genetics*; D015513:Oncogene Proteins / Q000235:genetics*; D000075223:Poly-ADP-Ribose Binding Proteins; D059003:Topoisomerase Inhibitors / Q000627:therapeutic use*; D014178:Translocation, Genetic / Q000235:genetics*
chemical_list: D002868:Chromosomal Proteins, Non-Histone; C084738:DEK protein, human; D015513:Oncogene Proteins; D000075223:Poly-ADP-Ribose Binding Proteins; D059003:Topoisomerase Inhibitors; D004250:DNA Topoisomerases, Type II
keywords: DEK-NUP214; Genes; Genetic analysis; Secondary AML