title: The Bethesda System for Reporting Thyroid Cytopathology: Proposed Modifications and Updates for the Second Edition from an International Panel.
abstract: The Bethesda System for Reporting Thyroid Cytology (TBSRTC) was proposed in 2007 at the National Cancer Institute Thyroid Fine Needle Aspiration State of the Art and Science Conference held in Bethesda, Maryland. The aim was to address the inconsistent and sometimes confusing reporting terminologies used for thyroid FNA throughout the world. The TBSRTC consists of 6 diagnostic categories, each associated with an implied risk of malignancy that translates directly into a clinical management algorithm. Since the publication of the TBSRTC cytology Atlas in January 2010, considerable experience has been gained regarding its application in cytology practice, clinical impact, and limitations. In conjunction with the International Academy of Cytology (IAC), an international panel composed of sixteen cytopathologists and an endocrinologist with special interest in thyroid cytology, including several co-authors of the 2010 TBSRTC Atlas, was created to: (1) analyze the current worldwide impact of TBSRTC, (2) report on the current state of TBSRTC based upon a review of the published literature, and (3) provide possible recommendations for a future update of TBSRTC. Herein, we summarize the panel's deliberations and key recommendations that our panel hopes will be useful during the preparation of the second edition of TBSRTC.
authors.affiliation: Department of Pathology, Geneva University Hospitals, Geneva, Switzerland.
authors.forename: Marc
authors.initials: M
authors.lastname: Pusztaszeri
authors.forename: Esther Diana
authors.initials: ED
authors.lastname: Rossi
authors.forename: Manon
authors.initials: M
authors.lastname: Auger
authors.forename: Zubair
authors.initials: Z
authors.lastname: Baloch
authors.forename: Justin
authors.initials: J
authors.lastname: Bishop
authors.forename: Massimo
authors.initials: M
authors.lastname: Bongiovanni
authors.forename: Ashish
authors.initials: A
authors.lastname: Chandra
authors.forename: Beatrix
authors.initials: B
authors.lastname: Cochand-Priollet
authors.forename: Guido
authors.initials: G
authors.lastname: Fadda
authors.forename: Mitsuyoshi
authors.initials: M
authors.lastname: Hirokawa
authors.forename: SoonWon
authors.initials: S
authors.lastname: Hong
authors.forename: Kennichi
authors.initials: K
authors.lastname: Kakudo
authors.forename: Jeffrey F
authors.initials: JF
authors.lastname: Krane
authors.forename: Ritu
authors.initials: R
authors.lastname: Nayar
authors.forename: Sareh
authors.initials: S
authors.lastname: Parangi
authors.forename: Fernando
authors.initials: F
authors.lastname: Schmitt
authors.forename: William C
authors.initials: WC
authors.lastname: Faquin
mesh_terms: D044963:Biopsy, Fine-Needle / Q000379:methods; D003581:Cytodiagnosis / Q000379:methods; D006801:Humans; D012306:Risk; D013961:Thyroid Gland / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology*