title: An analysis of factors affecting the mercury content in the human femoral bone.
abstract: The study was carried out to determine the content of mercury in bone tissue of the proximal femur (head and neck bone) of 95 patients undergoing total hip replacement due to osteoarthritis, using CF-AFS analytical technique. Furthermore, the investigations were aimed at assessing the impact of selected factors, such as age, gender, tobacco smoking, alcohol consumption, exposure to chemical substance at work, type of degenerative changes, clinical evaluation and radiological parameters, type of medications, on the concentration of mercury in the head and neck of the femur, resected in situ. Mercury was obtained in all samples of the head and neck of the femur (n = 190) in patients aged 25-91 years. The mean content of mercury for the whole group of patients was as follows: 37.1 ± 35.0 ng/g for the femoral neck and 24.2 ± 19.5 ng/g for the femoral head. The highest Hg contents were found in femoral neck samples, both in women and men, and they amounted to 169.6 and 176.5 ng/g, respectively. The research showed that the mercury content of bones can be associated with body mass index, differences in body anatomy, and gender. The uses of statistical analysis gave the possibility to define the influence of factors on mercury content in human femoral bones.
authors.affiliation: Faculty of Chemistry, Department of Analytical Chemistry, Adam Mickiewicz University in Poznań, Umultowska 89b, 61-614, Poznan, Poland. anettazf@amu.edu.pl.
authors.forename: A
authors.initials: A
authors.lastname: Zioła-Frankowska
authors.affiliation: Department of Spondyloorthopaedics and Biomechanics of the Spine, W. Dega University Hospital, Poznan University of Medical Sciences, 28 Czerwca 1956 135/147, 61-545, Poznan, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Dąbrowski
authors.affiliation: Department of Spondyloorthopaedics and Biomechanics of the Spine, W. Dega University Hospital, Poznan University of Medical Sciences, 28 Czerwca 1956 135/147, 61-545, Poznan, Poland.
authors.forename: Ł
authors.initials: Ł
authors.lastname: Kubaszewski
authors.affiliation: Department of Orthopedic and Traumatology, W. Dega University Hospital, Poznan University of Medical Sciences, 28 Czerwca 1956 135/147, 61-545, Poznan, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Rogala
authors.affiliation: Faculty of Chemistry, Department of Water and Soil Analysis, Adam Mickiewicz University in Poznań, Umultowska 89b, 61-614, Poznan, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Kowalski
authors.affiliation: Faculty of Chemistry, Department of Water and Soil Analysis, Adam Mickiewicz University in Poznań, Umultowska 89b, 61-614, Poznan, Poland. marcin.frankowski@amu.edu.pl.
authors.forename: M
authors.identifier: http://orcid.org/0000-0001-6315-3758
authors.initials: M
authors.lastname: Frankowski
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D004784:Environmental Monitoring; D005260:Female; D005270:Femur Head / Q000737:chemistry*; D005272:Femur Neck / Q000737:chemistry*; D006621:Hip Joint / Q000737:chemistry*; D006801:Humans; D008297:Male; D008628:Mercury / Q000032:analysis*; D008875:Middle Aged
chemical_list: D008628:Mercury
keywords: Body mass index; CV-AFS technique; Environment factors; Femoral bone; Mercury