title: Pre-surgical CT-assessment of neurogenic myositis ossificans of the hip and risk factors of recurrence: a series of 101 consecutive patients.
abstract: Neurogenic Myositis Ossificans (NMO) is a rare disabling pathology characterized by peri-articular heterotopic ossifications following severe peripheral or central nervous system injuries. It results in ankylosis and vessels or nerves compressions. Our study aimed to describe the pre-operative findings of patients with NMO of the hip using biphasic computerized tomography (CT).
  
  
  
  Between 2006 and 2012, we retrospectively analyzed 101 consecutive patients with hip NMO. We analyzed all CTs and surgical reports following a standardized grid depicting the osteoma and its relations with joint capsule, vessels and nerves and bone mineralization. We studied surgical complications and recurrence during follow-up. Chi2-test and Fischer's test were performed to compare qualitative values with respectively normal and non-normal distribution. Quantitative values were analyzed with a one factor analysis of variance (ANOVA) test. Agreement between pre-surgical CT and surgical observations was evaluated with Cohen's kappa test.
  
  
  
  Correlation between pre-operative CT and surgical findings was excellent regarding relationships with vessels (0,82) and was good concerning relationships with sciatic nerves (0.62) and with joint capsule (0.68). Close contact or disruption of joint capsule (p = 0.005), joint space narrowing (p = 0.007) and bone demineralization (p < 0.001) were correlated with NMO recurrence.
  
  
  
  Biphasic enhanced-CT allows pre-operative assessment of NMO with good correlation to surgical observations and helps prevent surgical complications.
authors.affiliation: APHP, Neuroradiology Department, Pitié-Salpêtrière Hospital, Paris, France.|Pierre and Marie Curie Faculty of Medicine, Sorbonne Universités, Paris, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Law-Ye
authors.affiliation: APHP, Radiology Department, Neuro-musculoskeletal Pole, Raymond Poincaré Hospital, 92380, Garches, France.|Versailles University, Paris-Saclay UMR 1179, End: icap, Saint-Quentin-en-Yvelines, France.
authors.forename: Chloé
authors.initials: C
authors.lastname: Hangard
authors.affiliation: APHP, Radiology Department, Neuro-musculoskeletal Pole, Raymond Poincaré Hospital, 92380, Garches, France.|Versailles University, Paris-Saclay UMR 1179, End: icap, Saint-Quentin-en-Yvelines, France.
authors.forename: Adrien
authors.initials: A
authors.lastname: Felter
authors.affiliation: APHP, Radiology Department, Neuro-musculoskeletal Pole, Raymond Poincaré Hospital, 92380, Garches, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Safa
authors.affiliation: APHP, Orthopedic surgery Department, Neuro-orthopedic Unit, Neuro-musculoskeletal Pole, Raymond Poincaré Hospital, 92380, Garches, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Denormandie
authors.affiliation: Versailles University, Paris-Saclay UMR 1179, End: icap, Saint-Quentin-en-Yvelines, France.|APHP, Rehabilitation Department and Pole, Raymond Poincaré Hospital, 92380, Garches, France.
authors.forename: François
authors.initials: F
authors.lastname: Genet
authors.affiliation: APHP, Radiology Department, Neuro-musculoskeletal Pole, Raymond Poincaré Hospital, 92380, Garches, France. robert.carlier@aphp.fr.|Versailles University, Paris-Saclay UMR 1179, End: icap, Saint-Quentin-en-Yvelines, France. robert.carlier@aphp.fr.|CIC 1429, Raymond Poincaré Hospital, 92380, Garches, France. robert.carlier@aphp.fr.
authors.forename: Robert-Yves
authors.initials: RY
authors.lastname: Carlier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000844:Ankylosis / Q000209:etiology / Q000517:prevention & control; D001177:Arthropathy, Neurogenic / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D009221:Myositis Ossificans / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D019637:Orthopedic Procedures / Q000009:adverse effects; D009999:Ossification, Heterotopic / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control; D011300:Preoperative Care / Q000379:methods; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult
keywords: Brain trauma; Neurogenic myositis ossificans; Osteoma; Paraplegia; Spinal cord injury