title: Anterior cruciate ligament rupture is associated with abnormal and asymmetrical lower limb loading during walking.
abstract: OBJECTIVE
  Anterior Cruciate Ligament (ACL) deficiency may result in abnormal lower limb loading with increased foot pronation. This study evaluated spatiotemporal parameters and plantar pressure distribution during walking in participants with and without an ACL rupture.
  
  
  METHODS
  Cross-sectional.
  
  
  METHODS
  Plantar pressure was measured in 42 unilateral ACL deficient (ACLD) participants and 32 healthy controls while walking barefoot. Spatiotemporal parameters, pressure distribution and center of pressure (CoP) during foot roll off were determined. Differences in spatiotemporal parameters and pressure distribution were analyzed using a Linear Mixed Model. CoP position was analyzed with one-way ANOVA.
  
  
  RESULTS
  ACLD participants had a longer contact time and earlier forefoot contact compared to controls. The ACLD side showed a shorter contact time and a faster roll off toward the forefoot compared to the ACL intact side. Compared to controls, ACLD participants had increased pressure under the medioproximal side of the midfoot. Within ACLD participants, the ACLD side had decreased pressure under the heel and increased pressure under the forefoot. Foot pronation was not different between groups or within ACLD participants. CoP of the ACLD participants was significantly more toward the toes during initial contact and toward the heel during foot flat.
  
  
  CONCLUSIONS
  Changes in lower limb loading during barefoot walking in ACLD participants are due to changes in roll off pattern, most likely in order to reduce anterior shear forces on the knee. Dynamic plantar pressure measurements may assist in evaluating and guiding interventions aimed at normalizing lower limb and knee biomechanics in ACL deficiency.
authors.affiliation: Institute of Sports Medicine, Peking University Third Hospital, PR China.
authors.forename: Hongshi
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Research, Development & Education, Sint Maartenskliniek, The Netherlands.
authors.forename: Noël
authors.initials: N
authors.lastname: Keijsers
authors.affiliation: Department of Rehabilitation Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address: h.l.d.horemans@erasmusmc.nl.
authors.forename: Herwin
authors.initials: H
authors.lastname: Horemans
authors.affiliation: Institute of Sports Medicine, Peking University Third Hospital, PR China.
authors.forename: Qinwei
authors.initials: Q
authors.lastname: Guo
authors.affiliation: Institute of Sports Medicine, Peking University Third Hospital, PR China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Yu
authors.affiliation: Department of Rehabilitation Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
authors.forename: Henk
authors.initials: H
authors.lastname: Stam
authors.affiliation: Department of Rehabilitation Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
authors.forename: Stephan
authors.initials: S
authors.lastname: Praet
authors.affiliation: Institute of Sports Medicine, Peking University Third Hospital, PR China. Electronic address: yingfang.ao@vip.sina.com.
authors.forename: Yingfang
authors.initials: Y
authors.lastname: Ao
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000070598:Anterior Cruciate Ligament Injuries / Q000503:physiopathology*; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D005528:Foot / Q000503:physiopathology*; D005684:Gait; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D008297:Male; D011403:Pronation; D016138:Walking; D016474:Weight-Bearing
keywords: Anterior cruciate ligament; Biomechanical phenomena; Gait; Knee; Plantar pressure; Spatio-temporal analysis