title: How to treat a fulminant erysipelas and sepsis caused by Myroides odoratimimus: case report and literature review.
abstract: We report a case of a 77-year old male who developed a fulminant erysipelas and sepsis, caused by Myroides odoratimimus. Selecting the optimal antibiotic therapy for the treatment of infections with M. odoratimimus is challenging due to limited clinical experience with this micro-organism and its reported multidrug-resistance. Review of previous studies concerning in vitro antibacterial susceptibility and clinical experience with M. odoratimimus resulted in six case reports describing bacteremia, soft tissue and bone infections, pneumonia and urinary tract infections. In vitro susceptibility to aminoglycosides, fluoroquinolones and trimethoprim/sulfamethoxazole is variable. Treatment of M. odoratimimus infections should be based on antimicrobial susceptibility testing results. In a majority of the case reports, including the present one, treatment with fluoroquinolones proved to be a good therapeutic option.
authors.affiliation: a Department of Microbiology and Immunology, Laboratory of Bacteriology and Mycology , KU Leuven - University of Leuven, University Hospitals Leuven , Leuven , Belgium.
authors.forename: Philippe
authors.initials: P
authors.lastname: Willems
authors.affiliation: b Department of Intensive Care , University Hospitals Leuven , Leuven , Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Muller
authors.affiliation: a Department of Microbiology and Immunology, Laboratory of Bacteriology and Mycology , KU Leuven - University of Leuven, University Hospitals Leuven , Leuven , Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Verhaegen
authors.affiliation: a Department of Microbiology and Immunology, Laboratory of Bacteriology and Mycology , KU Leuven - University of Leuven, University Hospitals Leuven , Leuven , Belgium.
authors.forename: Veroniek
authors.initials: V
authors.lastname: Saegeman
authors.affiliation: a Department of Microbiology and Immunology, Laboratory of Bacteriology and Mycology , KU Leuven - University of Leuven, University Hospitals Leuven , Leuven , Belgium.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Desmet
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004886:Erysipelas / Q000188:drug therapy* / Q000382:microbiology; D045826:Flavobacteriaceae Infections / Q000188:drug therapy*; D024841:Fluoroquinolones / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D018805:Sepsis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones
keywords: Antimicrobial susceptibility testing; Erysipelas; Flavobacterium odoratimimus; Myroides odoratimimus; Sepsis