title: Rapid Initiation of Antiretrovirals in Two Newly Diagnosed HIV-infected Infants.
abstract: We report our experience with 2 infants with in utero HIV-1 infection who began very early combination antiretroviral therapy within 4 hours of birth. Further neonatal studies of antiretroviral pharmacokinetics (PKs), safety, efficacy and treatment strategies are critically needed for the development of more potent regimens for use in HIV-infected infants.
authors.affiliation: From the *Department of Pediatrics, Boston University School of Medical, Boston, Massachusetts; †Section of Pediatric Infectious Diseases, Boston Medical Center, Boston, Massachusetts; and ‡Division of Infectious Diseases, Department of Pediatrics, Emory University, Atlanta, Georgia.
authors.forename: Diana F
authors.initials: DF
authors.lastname: Clarke
authors.forename: Inci
authors.initials: I
authors.lastname: Yildirim
authors.forename: Ellen R
authors.initials: ER
authors.lastname: Cooper
mesh_terms: D044966:Anti-Retroviral Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology / Q000821:virology*; D015497:HIV-1 / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D012367:RNA, Viral / Q000097:blood; D061665:Time-to-Treatment; D019562:Viral Load
chemical_list: D044966:Anti-Retroviral Agents; D012367:RNA, Viral