title: Successful Treatment of Ascites using a Denver®Peritoneovenous Shunt in a Patient with Paroxysmal Nocturnal Hemoglobinuria and Budd-Chiari syndrome.
abstract: A 56-year-old man was diagnosed with aplastic anemia and paroxysmal nocturnal hemoglobinuria at 43 years of age and treatment with cyclosporin A was started. Liver cirrhosis, ascites, and thrombus in the hepatic veins were found at 56 years of age and Budd-Chiari syndrome (BCS) was diagnosed according to angiography findings. He was treated with diuretics and paracentesis was performed several times, but with limited efficacy. A Denver®peritoneovenous shunt (PVS) was inserted into the right jugular vein; his ascites and renal function improved immediately and his general condition has remained good for 12 months since starting the above treatment regimen. A PVS is a treatment option for ascites due to BCS.
authors.affiliation: Institute of Gastroenterology, Department of Internal Medicine, Tokyo Women's Medical University, Japan.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Kogiso
authors.forename: Etsuko
authors.initials: E
authors.lastname: Hashimoto
authors.forename: Taito
authors.initials: T
authors.lastname: Ito
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Hara
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ikarashi
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Kodama
authors.forename: Makiko
authors.initials: M
authors.lastname: Taniai
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Torii
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yoshinaga
authors.forename: Satoru
authors.initials: S
authors.lastname: Morita
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Junji
authors.initials: J
authors.lastname: Tanaka
authors.forename: Shuji
authors.initials: S
authors.lastname: Sakai
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Tokushige
mesh_terms: D000741:Anemia, Aplastic / Q000150:complications*; D001201:Ascites / Q000150:complications / Q000601:surgery*; D006502:Budd-Chiari Syndrome / Q000150:complications / Q000601:surgery*; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications / Q000601:surgery*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008297:Male; D008875:Middle Aged; D010536:Peritoneovenous Shunt; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000150:complications / Q000601:surgery*