title: An Investigation of Topics and Trends of Tracheal Replacement Studies Using Co-Occurrence Analysis.
abstract: This study evaluated tracheal regeneration studies using scientometric and co-occurrence analysis to identify the most important topics and assess their trends over time. To provide the adequate search options, PubMed, Scopus, and Web of Science (WOS) were used to cover various categories such as keywords, countries, organizations, and authors. Search results were obtained by employing Bibexcel. Co-occurrence analysis was applied to evaluate the publications. Finally, scientific maps, author's network, and country contributions were depicted using VOSviewer and NetDraw. Furthermore, the first 25 countries and 130 of the most productive authors were determined. Regarding the trend analysis, 10 co-occurrence terms out of highly frequent words were examined at 5-year intervals. Our findings indicated that the field of trachea regeneration has tested different approaches over the time. In total, 65 countries have contributed to scientific progress both in experimental and clinical fields. Special keywords such as tissue engineering and different types of stem cells have been increasingly used since 1995. Studies have addressed topics such as angiogenesis, decellularization methods, extracellular matrix, and mechanical properties since 2011. These findings will offer evidence-based information about the current status and trends of tracheal replacement research topics over time, as well as countries' contributions.
authors.affiliation: 1 Tracheal Diseases Research Center (TDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences , Tehran, Iran .
authors.forename: Fariba
authors.initials: F
authors.lastname: Ghorbani
authors.affiliation: 2 Sabzevar University of Medical Sciences, Faculty of Medicine, Sabzevar, Iran .
authors.forename: Mansoureh
authors.initials: M
authors.lastname: Feizabadi
authors.affiliation: 1 Tracheal Diseases Research Center (TDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences , Tehran, Iran .
authors.forename: Roya
authors.initials: R
authors.lastname: Farzanegan
authors.affiliation: 3 University of Zabol, Faculty of Humanities, Department of Information Science and Knowledge Studies, Zabol, Iran .
authors.forename: Esmaeil
authors.initials: E
authors.lastname: Vaziri
authors.affiliation: 4 Department of Tissue Engineering & Applied Cell Sciences, School of Advanced Technologies in Medicine , Tehran, Iran .
authors.forename: Saeed
authors.initials: S
authors.lastname: Samani
authors.affiliation: 5 Faculty of Health, York University , Toronto, Canada .
authors.forename: Seyedamirmohammad
authors.initials: S
authors.lastname: Lajevardi
authors.affiliation: 4 Department of Tissue Engineering & Applied Cell Sciences, School of Advanced Technologies in Medicine , Tehran, Iran .
authors.forename: Lida
authors.initials: L
authors.lastname: Moradi
authors.affiliation: 1 Tracheal Diseases Research Center (TDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences , Tehran, Iran .
authors.forename: Mohammad Behgam
authors.initials: MB
authors.lastname: Shadmehr
mesh_terms: D000818:Animals; D003299:Cooperative Behavior; D019992:Databases as Topic; D006801:Humans; D011642:Publications / Q000639:trends*; D023822:Tissue Engineering / Q000379:methods* / Q000639:trends*; D014132:Trachea / Q000502:physiology*
keywords: regeneration; replacement; scientometrics; therapeutic substitution; trachea; transplantation; trends