title: Why is neoadjuvant chemoradiation therapy underused for locally advanced rectal cancer?
authors.affiliation: a Department of Biosciences Laboratory , Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS , Meldola , Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Molinari
authors.affiliation: b Department of Medical Oncology , Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS , Meldola , Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Passardi
mesh_terms: D000367:Age Factors; D059186:Chemoradiotherapy, Adjuvant / Q000009:adverse effects / Q000592:standards / Q000706:statistics & numerical data*; D015897:Comorbidity; D019983:Guideline Adherence; D054625:Healthcare Disparities; D006801:Humans; D020360:Neoadjuvant Therapy / Q000009:adverse effects / Q000592:standards / Q000706:statistics & numerical data*; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D012307:Risk Factors; D016896:Treatment Outcome
keywords: Chemotherapy; multimodal treatment; neoadjuvant therapy; radiotherapy; rectal cancer