title: [Association between parental exposure to environmental risk factors and the risk of childhood acute lymphoblastic leukemia].
abstract: Objective:To investigate the association between parental environmental risk factors exposure and the risk for childhood acute lymphoblastic leukemia (ALL).Methods:A total of 179 ALL children cases were selected in Tianjin Blood Disease Hospital and 136 healthy children matched by age, gender and living place were selected in 2015 for a case control study. The data were analyzed with univariate and multivariate non conditional logistic regression models.Results:The results of multivariate logistic regression analysis indicated that sex, history of abortion, exposure in a smoking environment during pregnancy, catching a cold, taking antipyretic analgesics, maternal exposure to air purifying agent, father' s occupational exposure to petroleum products and home decoration during pregnancy were associated with the risk of childhood ALL (P<0.05) and the results of multivariate logistic regression analysis indicated that sex, history of abortion, catching a cold, father's occupational exposure to petroleum products and home decoration during pregnancy were associated with the risk of childhood ALL (P<0.05).Conclusion:The five factors including sex, history of abortion, catching a cold, father' s occupational exposure to petroleum products and home decoration during pregnancy were risk factors for childhood ALL.
authors.affiliation: Graduate School of Tianjin Medical University, Tianjin 300070, China.
authors.forename: J W
authors.initials: JW
authors.lastname: Zhang
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Zeng
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: L
authors.initials: L
authors.lastname: Zhao
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Gu
mesh_terms: D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005220:Fathers; D005260:Female; D006801:Humans; D007223:Infant; D016015:Logistic Models; D008297:Male; D018811:Maternal Exposure; D016273:Occupational Exposure; D018812:Paternal Exposure; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000453:epidemiology*; D011247:Pregnancy; D012307:Risk Factors; D014028:Tobacco Smoke Pollution
chemical_list: D014028:Tobacco Smoke Pollution