title: Distribution of Vaccine-Type Human Papillomavirus Does Not Differ by Race or Ethnicity Among Unvaccinated Young Women.
abstract: Previous studies have demonstrated racial and ethnic differences in the distribution of human papillomavirus (HPV) types among adult women with cervical precancers. The aim of this study was to determine whether the distribution of vaccine-targeted HPV types varies by race/ethnicity among unvaccinated young women.
  
  
  
  A secondary analysis was performed using data from four studies of sexually experienced, unvaccinated, 13-26-year-old women. Participants completed surveys and provided a cervicovaginal swab for HPV DNA testing. Multivariable logistic regression analyses were performed to examine whether race, ethnicity, and other factors were associated with type-specific HPV infection among the overall sample and among HPV-infected participants. Models controlled for age, HPV knowledge, sexual behaviors, substance use, and random study effect.
  
  
  
  The mean age of participants (N = 841) was 19.3 years; 64.4% were black and 8.9% Hispanic. Black women were more likely than white women to be positive for ≥1 HPV type (odds ratio [OR] 1.83, 95% CI 1.30-2.58) and Hispanic women were less likely than non-Hispanic women to be positive for ≥1 HPV type (OR 0.47, 95% CI 0.24-0.92). However, among all young women and HPV-infected women, neither race nor ethnicity was associated with positivity for HPV types targeted by the following vaccines: 2-valent (HPV16 and/or 18), 4-valent (HPV6, 11, 16, and/or 18), or 9-valent (HPV6, 11, 16, 18, 31, 33, 45, 52, and/or 58).
  
  
  
  The prevalence of HPV types targeted by the 2-valent, 4-valent, and 9-valent vaccines did not differ by race or ethnicity among all and among HPV-infected women in this sample.
authors.affiliation: 1 University of Cincinnati College of Medicine , Cincinnati, Ohio.
authors.forename: Dana
authors.initials: D
authors.lastname: Whittemore
authors.affiliation: 1 University of Cincinnati College of Medicine , Cincinnati, Ohio.|2 Department of Pediatrics, Cincinnati Children's Hospital Medical Center , Cincinnati, Ohio.
authors.forename: Lili
authors.initials: L
authors.lastname: Ding
authors.affiliation: 1 University of Cincinnati College of Medicine , Cincinnati, Ohio.|2 Department of Pediatrics, Cincinnati Children's Hospital Medical Center , Cincinnati, Ohio.
authors.forename: Lea E
authors.initials: LE
authors.lastname: Widdice
authors.affiliation: 3 Department of Medicine, Indiana University , Indianapolis, Indiana.
authors.forename: Darron A
authors.initials: DA
authors.lastname: Brown
authors.affiliation: 1 University of Cincinnati College of Medicine , Cincinnati, Ohio.|2 Department of Pediatrics, Cincinnati Children's Hospital Medical Center , Cincinnati, Ohio.
authors.forename: David I
authors.initials: DI
authors.lastname: Bernstein
authors.affiliation: 4 Departments of Oncology and Epidemiology and Biotatistics, McGill University , Montreal, Canada .
authors.forename: Eduardo L
authors.initials: EL
authors.lastname: Franco
authors.affiliation: 1 University of Cincinnati College of Medicine , Cincinnati, Ohio.|2 Department of Pediatrics, Cincinnati Children's Hospital Medical Center , Cincinnati, Ohio.
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Kahn
mesh_terms: D000293:Adolescent; D000328:Adult; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D054624:Health Status Disparities; D006801:Humans; D016015:Logistic Models; D015999:Multivariate Analysis; D027383:Papillomaviridae / Q000145:classification / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000627:therapeutic use*; D044469:Racial Groups / Q000706:statistics & numerical data*; D012725:Sexual Behavior / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines
keywords: epidemiology; ethnicity; human papillomavirus; race; vaccine