title: Role of fluoro-2-deoxyglucose positron emission tomography for the detection of gastrointestinal tract lesions in patients with lung cancer.
abstract: BACKGROUND
  The purpose of this study was to clarify the clinical characteristics of lung cancer patients with abnormal accumulation of fluoro-2-deoxyglucose (FDG) in the gastrointestinal tract imaged by positron emission tomography (PET).
  
  
  METHODS
  Of 1071 consecutive patients with primary lung cancer who underwent PET from October 2005 through to March 2010, 25 patients (2.3%) showed localized abnormal FDG accumulation in the gastrointestinal tract. We retrospectively compared the location of abnormal accumulation in the gastrointestinal tract, the maximum standardized uptake value in 1 hour, and final clinical diagnosis.
  
  
  RESULTS
  Of the 25 cases, 12 (48%) were true PET-positive cases (esophageal cancer in one case, gastric cancer in one, colorectal cancer in seven, gastrointestinal stromal tumor in one, and lung cancer metastasis to the stomach and small intestine in one patient each). The 13 cases with false PET-positives were gastric polyp in one, gastritis in four, colon polyp in two, diverticulitis in one, and normal physiological accumulation in five. There was also a significant difference between malignancy and benign intestinal accumulation excluding the stomach (P = 0.002).
  
  
  CONCLUSIONS
  PET was useful for screening the gastrointestinal tract (except the stomach) for malignancy in lung cancer patients.
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Isobe
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Hata
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Sakaguchi
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Keita
authors.initials: K
authors.lastname: Sato
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Go
authors.initials: G
authors.lastname: Sano
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Keishi
authors.initials: K
authors.lastname: Sugino
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Sakamoto
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Yujiro
authors.initials: Y
authors.lastname: Takai
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Shibuya
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Keigo
authors.initials: K
authors.lastname: Takagi
authors.affiliation: Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, JapanDepartment of Chest Surgery, Toho University Omori Medical Center, Tokyo, JapanDepartment of Surgical Pathology, Toho University Omori Medical Center, Tokyo, Japan.
authors.forename: Sakae
authors.initials: S
authors.lastname: Homma
keywords: Double cancer; FDG-PET; gastrointestinal tract cancer; lung cancer; metastasis of the gastrointestinal tract