title: Prevalence of hypothyroidism during pregnancy in a highly specialised referral centre in Mexico.
abstract: In order to determine the prevalence of overt and subclinical hypothyroidism, and isolated hypothyroxinemia during pregnancy, thyroid hormone reference values established by UMAE HGO4, IMSS in Mexico City and those suggested by the American Thyroid Association (ATA) were used. All pregnant patients, whose thyroid function was measured and whose pregnancy was monitored and resolved in UMAE HGO4, IMSS from 1 January to 31 December 2013, were included. Significant differences (p = .00419) were observed in the frequency of subclinical hypothyroidism, being higher when using ATA criteria (18.21% vs. 9.66%). The prevalence rate (UMAE HGO4 vs. ATA) for overt hypothyroidism was 1.11 vs. 1.63, for subclinical hypothyroidism 0.84 vs. 1.41 and for isolated hypothyroxinemia 3.17 vs. 2.79 per 1000 consults during the study period. Independently of prevalence rate, it is essential to provide information on the possible risks involved in pregnancy to all women of childbearing age at the time of hypothyroidism diagnosis.
authors.affiliation: a Unidad de Investigación Médica en Medicina Reproductiva, Coordinación de Investigación en Salud, Instituto Mexicano del Seguro Social, Laboratorio K, Colonia Tizapan San Angel, Delegación Álvaro Obregón , Ciudad de México.
authors.forename: Eunice
authors.initials: E
authors.lastname: López-Muñoz
authors.affiliation: b Servicio de Obstetricia, Unidad Médica de Alta Especialidad, Hospital de Gineco Obstetricia No. 4 Luis Castelazo Ayala, Instituto Mexicano del Seguro Social , Ciudad de México.
authors.forename: Jorge Antonio
authors.initials: JA
authors.lastname: Ibarra-Avalos
authors.affiliation: c Laboratorio Clínico, Unidad Médica de Alta Especialidad, Hospital de Gineco Obstetricia No. 4 Luis Castelazo Ayala, Instituto Mexicano del Seguro Social , Ciudad de México.
authors.forename: Rosario Guadalupe
authors.initials: RG
authors.lastname: Chan-Verdugo
authors.affiliation: d Unidad de Cuidados Intensivos Neonatales, Unidad Médica de Alta Especialidad, Hospital de Gineco Obstetricia No. 4 Luis Castelazo Ayala, Instituto Mexicano del Seguro Social , Ciudad de México.
authors.forename: Leovigildo
authors.initials: L
authors.lastname: Mateos-Sánchez
authors.affiliation: e Servicio de Perinatología, Unidad Médica de Alta Especialidad, Hospital de Gineco Obstetricia No. 4 Luis Castelazo Ayala, Instituto Mexicano del Seguro Social , Ciudad de México.
authors.forename: Olivia
authors.initials: O
authors.lastname: Sánchez-Rodríguez
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000453:epidemiology*; D008800:Mexico / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000209:etiology; D015995:Prevalence; D012017:Referral and Consultation / Q000706:statistics & numerical data
keywords: Isolated hypothyroxinemia; maternal hypothyroidism; overt hypothyroidism; pregnancy; prevalence; subclinical hypothyroidism