title: Prediction of Embolization Area after Conventional Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Using SYNAPSE VINCENT.
abstract: OBJECTIVE
  Transcatheter arterial chemoembolization (TACE) is one of the most effective therapeutic options for hepatocellular carcinoma (HCC) and it is important to protect residual liver function after treatment as well as the effect. To reduce the liver function deterioration, we evaluated the automatic software to predict the embolization area of TACE in 3 dimensions.
  
  
  METHODS
  Automatic prediction software of embolization area was used in chemoembolization of 7 HCCs. Embolization area of chemoembolization was evaluated within 1 week CT findings after TACE and compared simulated area using automatic prediction software.
  
  
  RESULTS
  The maximal diameter of these tumors is in the range 12-42 mm (24.6 ± 9.5 mm). The average time for detecting tumor-feeding branches was 242 s. The total time to detect tumor-feeding branches and simulate the embolization area was 384 s. All cases could detect all tumor-feeding branches of HCC, and the expected embolization area of simulation with automatic prediction software was almost the same as the actual areas, as shown by CT after TACE.
  
  
  CONCLUSIONS
  This new technology has possibilities to reduce the amount of contrast medium used, protect kidney function, decrease radiation exposure, and improve the therapeutic effect of TACE.
authors.forename: Chikara
authors.initials: C
authors.lastname: Ogawa
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Minami
authors.forename: Masahiro
authors.initials: M
authors.lastname: Morita
authors.forename: Teruyo
authors.initials: T
authors.lastname: Noda
authors.forename: Soichi
authors.initials: S
authors.lastname: Arasawa
authors.forename: Masako
authors.initials: M
authors.lastname: Izuta
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kubo
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Matsunaka
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tamaki
authors.forename: Mitsushige
authors.initials: M
authors.lastname: Shibatoge
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kudo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction / Q000379:methods; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D003287:Contrast Media; D005544:Forecasting; D019786:Gadolinium DTPA; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D018810:Magnetic Resonance Angiography / Q000379:methods; D061330:Multidetector Computed Tomography / Q000379:methods; D011172:Portography / Q000379:methods; D011873:Radiology Information Systems; D012984:Software
chemical_list: D003287:Contrast Media; C073590:gadolinium ethoxybenzyl DTPA; D019786:Gadolinium DTPA