title: Management of gynaecologic plasmacytoma: A review article.
abstract: In contrast to multiple myeloma (MM) which exhibits diffuse bone marrow and other organ involvement, solitary plasmacytomas carry a favourable prognosis. Extramedullary plasmacytomas (EMP) are a unique form of plasma cell neoplasms. These tumours are rare in the female reproductive tract. Only 24 cases of gynaecologic plasmacytomas were reported to date (7 cases were solitary plasmacytomas and 17 cases were either part of disseminated MM with involvement of a gynaecologic organ or were lacking complete work-up to rule out MM). The standard care of gynaecologic solitary EMP is surgical resection alone when feasible. Adjuvant radiation therapy may be considered for adverse prognostic factors such as positive resection margins. MM with gynaecologic organ involvement should be managed with systemic therapy and defer local therapies to symptomatic progression.
authors.affiliation: a Department of Radiation Oncology , Henry Ford Hospital , Detroit , MI , USA.
authors.forename: Aharon M
authors.initials: AM
authors.lastname: Feldman
authors.affiliation: b Department of Pathology , Henry Ford Hospital , Detroit , MI , USA.
authors.forename: Ziying
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: c Division of Gynaecologic Oncology, Department of Women's Health Services , Henry Ford Hospital , Detroit , MI , USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Buekers
authors.affiliation: a Department of Radiation Oncology , Henry Ford Hospital , Detroit , MI , USA.
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Elshaikh
mesh_terms: D005260:Female; D005833:Genital Neoplasms, Female / Q000628:therapy*; D006801:Humans; D009101:Multiple Myeloma / Q000628:therapy*; D010954:Plasmacytoma / Q000628:therapy*
keywords: Extramedullary; multiple myeloma; ovarian neoplasms; plasmacytoma; uterine neoplasms; vaginal neoplasms