title: Substrate-Controlled Selectivity Switch in the Three-Component Coupling Involving Arynes, Aromatic Tertiary Amines, and CO2.
abstract: The transition-metal-free multicomponent coupling involving arynes, aromatic tertiary amines, and CO2is reported. The reaction exhibits switchable selectivity depending on the electronic nature of the aromatic amines used. With amines bearing electron-releasing/neutral groups as the nucleophilic trigger, the reaction afforded 2-arylamino benzoates via a nitrogen to oxygen alkyl group migration. Employing electron-deficient amines in the reaction furnished 2-aminoaryl benzoates proceeding via the aryl to aryl amino group migration resembling a Smiles rearrangement.
authors.affiliation: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors.forename: Sachin Suresh
authors.initials: SS
authors.lastname: Bhojgude
authors.affiliation: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors.forename: Tony
authors.initials: T
authors.lastname: Roy
authors.forename: Rajesh G
authors.initials: RG
authors.lastname: Gonnade
authors.affiliation: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors.forename: Akkattu T
authors.initials: AT
authors.lastname: Biju