title: Effects of Ready-to-Eat-Cereals on Key Nutritional and Health Outcomes: A Systematic Review.
abstract: BACKGROUND
  In many countries breakfast cereals are an important component of breakfast. This systematic review assesses the contribution of consumption of ready-to eat cereal (RTEC) to the recommended nutrient intake. Furthermore, the effects of RTEC consumption on key health parameters are investigated as well as health promoting properties of RTEC.
  
  
  METHODS
  The Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and CINAHL have been searched up till 16th of June 2015. Randomized controlled trials were excluded if RTEC were used during hypocaloric diets, if RTEC were eaten at other times than breakfast and if breakfasts included other products than RTEC, milk and fruit. Observational studies were excluded when "breakfast cereals" were not defined or their definition included cooked cereals. From cross-sectional studies only data concerning energy and nutrient intake as well as micronutrient status were used.
  
  
  RESULTS
  From 4727 identified citations 64 publications met the inclusion criteria of which 32 were cross-sectional studies, eight prospective studies and 24 randomized controlled trials. Consumption of RTEC is associated with a healthier dietary pattern, concerning intake of carbohydrates, dietary fiber, fat and micronutrients, however total sugar intake is higher. Persons consuming RTEC frequently (≥ 5 times/week) have a lower risk of inadequate micronutrient intake especially for vitamin A, calcium, folate, vitamin B 6, magnesium and zinc. Evidence from prospective studies suggests that whole grain RTEC may have beneficial effects on hypertension and type 2 diabetes. Consumption of RTEC with soluble fiber helps to reduce LDL cholesterol in hypercholesterolemic men and RTEC fortified with folate can reduce plasma homocysteine.
  
  
  CONCLUSIONS
  One of the review's strengths is its thorough ex/inclusion of studies. Limitations are that results of observational studies were based on self-reported data and that many studies were funded by food-industry.
  
  
  CONCLUSIONS
  Consumption of RTEC, especially of fiber-rich or whole grain RTEC, is implicated with several beneficial nutritional and health outcomes. The effect on body weight, intestinal health and cognitive function needs further evaluation. Of concern is the higher total sugar intake associated with frequent RTEC consumption.
authors.affiliation: University Medical Center Groningen, University of Groningen, Center for Medical Biomics, Groningen, The Netherlands.|Nutrition Reviewed, Murnau, Germany.
authors.forename: Marion G
authors.initials: MG
authors.lastname: Priebe
authors.affiliation: Cereal Partners Worldwide, Lausanne 1008, Switzerland.
authors.forename: Jolene R
authors.initials: JR
authors.lastname: McMonagle
mesh_terms: D002318:Cardiovascular Diseases / Q000517:prevention & control; D003071:Cognition / Q000502:physiology; D016208:Databases, Factual; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control; D002523:Edible Grain; D002149:Energy Intake; D006801:Humans; D018977:Micronutrients / Q000008:administration & dosage*; D009753:Nutritive Value
chemical_list: D018977:Micronutrients