title: Outcomes with type 2 myocardial infarction compared with non-ischaemic myocardial injury.
abstract: To identify patients with type 2 myocardial infarction (MI) and patients with non-ischaemic myocardial injury (NIMI) and to compare their prognosis with those of patients with type 1 MI.
  
  
  
  A retrospective observational study was performed in 1010 patients admitted to the emergency department of a university hospital with at least one troponin I test between 2012 and 2013. Participants were identified using laboratory records and divided into three groups: type 1 MI (rupture of atheromatous plaque), type 2 MI (imbalance between myocardial oxygen supply and/or demand) and NIMI (patients who did not meet diagnostic criteria for type 1 or type 2 MI). Clinical characteristics and 2-year outcomes were analysed.
  
  
  
  Patients with type 2 MI and NIMI were older, with higher proportion of women and more comorbidities than patients with type 1 MI. Absolute mortality and the adjusted risk for all-cause mortality in both groups were significantly higher than that of patients with type 1 MI (39.7%, HR: 1.41 95% CI 1.02 to 1.94, p=0.038 and 40.0%, HR: 1.54 95% CI 1.16 to 2.04, p=0.002, respectively). Patients with type 2 MI and NIMI tended to present more readmissions due to heart failure (16.5%, HR: 1.55 95% CI 0.87 to 2.76, p=0.133 and 12.3%, HR: 1.15 95% CI 0.70 to 1.90, p=0.580) and less readmission rates due to acute coronary syndrome (ACS) than patients with type 1 MI (2.1%, HR: 0.11 95% CI 0.04 to 0.31, p<0.001 and 4.3%, HR: 0.22 95% CI 0.12 to 0.41, p<0.001), CONCLUSIONS: Patients diagnosed with type 2 MI and NIMI have higher rates of mortality and lower readmission rates for ACS compared with patients with type 1 MI.
authors.affiliation: Department of Cardiology, Joan XXIII University Hospital, Tarragona, Spain.|Pere Virgili Health Research Institute, Rovira i Virgili University, Tarragona, Spain.
authors.forename: German
authors.identifier: 0000-0001-9667-7507
authors.initials: G
authors.lastname: Cediel
authors.affiliation: Department of Cardiology, Joan XXIII University Hospital, Tarragona, Spain.|Pere Virgili Health Research Institute, Rovira i Virgili University, Tarragona, Spain.
authors.forename: Maribel
authors.initials: M
authors.lastname: Gonzalez-Del-Hoyo
authors.affiliation: Department of Cardiology, Joan XXIII University Hospital, Tarragona, Spain.|Pere Virgili Health Research Institute, Rovira i Virgili University, Tarragona, Spain.
authors.forename: Anna
authors.initials: A
authors.lastname: Carrasquer
authors.affiliation: Department of Clinical Analysis, Joan XXIII University Hospital, Tarragona, Spain.
authors.forename: Rafael
authors.initials: R
authors.lastname: Sanchez
authors.affiliation: Pere Virgili Health Research Institute, Rovira i Virgili University, Tarragona, Spain.|Emergency Department, Joan XXIII University Hospital, Tarragona, Spain.
authors.forename: Carme
authors.initials: C
authors.lastname: Boqué
authors.affiliation: Department of Cardiology, Joan XXIII University Hospital, Tarragona, Spain.|Pere Virgili Health Research Institute, Rovira i Virgili University, Tarragona, Spain.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Bardají
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D018450:Disease Progression; D004636:Emergency Service, Hospital; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D010359:Patient Readmission; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D019210:Troponin I / Q000097:blood; D015854:Up-Regulation
chemical_list: D015415:Biomarkers; D019210:Troponin I