title: Molecular Breast Imaging for Screening in Dense Breasts: State of the Art and Future Directions.
abstract: OBJECTIVE
  The purposes of this review are to discuss the motivation for supplemental screening, to address molecular breast imaging (MBI) radiation dose concerns, and to provide an updated guide to current MBI technology, clinical protocols, and screening performance. Future directions of MBI are also discussed.
  
  
  CONCLUSIONS
  MBI offers detection of mammographically occult cancers in women with dense breasts. Although MBI has been under investigation for nearly 15 years, it has yet to gain widespread adoption in breast screening.
authors.affiliation: 1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55955.
authors.forename: Carrie B
authors.initials: CB
authors.lastname: Hruska
mesh_terms: D015502:Absorptiometry, Photon; D014408:Biomarkers, Tumor / Q000378:metabolism*; D000071060:Breast Density; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism*; D055088:Early Detection of Cancer / Q000639:trends*; D005260:Female; D005544:Forecasting; D006801:Humans; D008327:Mammography / Q000639:trends*; D057054:Molecular Imaging / Q000639:trends*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor
keywords: breast density; breast screening; molecular breast imaging; radiation risk