title: Cryptoporic acid S, a new drimane-type sesquiterpene ether of isocitric acid from the fruiting bodies of Cryptoporus volvatus.
abstract: A new drimane-type sesquiterpene with an isocitric acid moiety, cryptoporic acid S (1), together with six known compounds, cryptoporic acid D (2), β-sitosterol (3), β-daucosterol (4), stigmast-4-en-3-one (5), ergosterol (6), and (22E,24R)-ergosta-7,22-diene-3β,5α,6β-triol (7), was isolated from the fruiting bodies of Cryptoporus volvatus. The structures of these compounds were established on the basis of UV, IR, MS, 1D and 2D NMR analysis. In the meanwhile, compounds 1 and 2 were evaluated for antioxidant activity using the methods of 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity (DPPH-RSA) and ferric reducing antioxidant power (FRAP) assay, and they exhibited moderate antioxidant activities.
authors.affiliation: a Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100193 , China.
authors.forename: Jun-Chi
authors.initials: JC
authors.lastname: Wang
authors.affiliation: a Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100193 , China.
authors.forename: Guang-Zhi
authors.initials: GZ
authors.lastname: Li
authors.affiliation: a Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100193 , China.
authors.forename: Na
authors.initials: N
authors.lastname: Lv
authors.affiliation: a Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100193 , China.
authors.forename: Lian-Gang
authors.initials: LG
authors.lastname: Shen
authors.affiliation: b Xinjiang Institute of Chinese Materia Medica and Ethical Materia Medica , Urumqi 830002 , China.
authors.forename: Lei-Ling
authors.initials: LL
authors.lastname: Shi
authors.affiliation: a Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100193 , China.
authors.forename: Jian-Yong
authors.initials: JY
authors.lastname: Si
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D002681:China; D055453:Coriolaceae / Q000737:chemistry*; D004875:Ergosterol / Q000737:chemistry; D004987:Ethers; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D007523:Isocitrates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D010851:Picrates / Q000494:pharmacology; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012855:Sitosterols / Q000737:chemistry; D013265:Stigmasterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D004987:Ethers; D007523:Isocitrates; D010851:Picrates; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D012855:Sitosterols; C000621766:cryptoporic acid S; C437376:drimane; C488470:stigmast-4-en-3-one; C069196:cryptoporic acid D; C025473:gamma-sitosterol; D013265:Stigmasterol; C034219:isocitric acid; C004931:1,1-diphenyl-2-picrylhydrazyl; D004875:Ergosterol
keywords: Cryptoporus volvatus; Polyporaceae; antioxidant activity; cryptoporic acid derivatives; sesquiterpene