title: Progenitor cells in sarcoidosis.
abstract: Sarcoidosis is a systemic disease of unknown initiating factor. In the pathogenesis of the disease it emphasizes the importance of genetic factors, specificity of inflammation and toll-like receptors. No less important cell in the development of lesions is fibrocyte, which creates the final image of the disease in the form of fibrosis of the lung parenchyma. Data from experimental and clinical studies indicate that the progenitor cell can turn into fibrocyte. This indicates the possibility of controlling the process, which is already implemented in practice in Lung Institute in Pittsburgh, USA. The results of these new therapies are encouraging and suggest a new way to treat patients with pulmonary pathology, including sarcoidosis.
authors.affiliation: EMC Medical Institute SA - Department of Internal Medicine and Lung Disease, Hospital st. Anna in Piaseczno, Poland.
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Płusa
mesh_terms: D006801:Humans; D012507:Sarcoidosis / Q000628:therapy*; D033581:Stem Cell Transplantation
keywords: Fibrocyte; progenitor cell; sakroidoza