title: Impact of Body Mass Index on Outcomes of In Vitro Fertilization/Intracytoplasmic Sperm Injection Among Polycystic Ovarian Syndrome Patients.
abstract: BACKGROUND
  The aim of this study is to assess the effect of body mass index (BMI) on outcomes of in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) among polycystic ovarian syndrome (PCOS) and non-PCOS patients.
  
  
  METHODS
  This was a retrospective cohort study that was performed in the Second Hospital of Hebei Medical University. Patients who were under 35 years old were included in the study and were divided into four groups based on their BMI. The number of retrieved oocytes, implantation rate, clinical pregnancy rate, miscarriage rate and live births among PCOS and non-PCOS patients were compared between different BMIs.
  
  
  RESULTS
  IVF/ICSI pregnancies in obese PCOS women had a considerably higher risk of miscarriage and low rate of clinical pregnancy than in non-obese PCOS pregnancies. However, in non-PCOS patient, obesity significantly elevated miscarriage rate but did not affect clinical pregnancy rate.
  
  
  CONCLUSIONS
  Obesity in PCOS patients led to poor outcomes of IVF/ICSI.
authors.affiliation: Department of Reproduction, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
authors.forename: Na
authors.initials: N
authors.lastname: Cui
authors.forename: Huixia
authors.initials: H
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Yueming
authors.initials: Y
authors.lastname: Xu
authors.forename: Lei
authors.initials: L
authors.lastname: Jiang
authors.forename: Aimin
authors.initials: A
authors.lastname: Yang
authors.forename: Guimin
authors.initials: G
authors.lastname: Hao
mesh_terms: D000328:Adult; D015992:Body Mass Index; D010064:Embryo Implantation; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D011085:Polycystic Ovary Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000706:statistics & numerical data*; D016896:Treatment Outcome