title: The Sequestration of Oxy-Polybrominated Diphenyl Ethers in the Nudibranchs Miamira magnifica and Miamira miamirana.
abstract: A series of oxy-polybrominated diphenyl ethers (O-PBDEs) has been isolated from the extracts ofMiamira magnificaandMiamira miamiranacollected from Queensland, Australia.M. magnificasequesters the new OH-PBDE1and six known OH-PBDEs containing four to six bromines (2-7).M. miamiranaalso accumulates known tribromo- and tetrabromo OMe-PBDEs8-10in both mantle and viscera tissues. To date,Miamirais the only genus of the family Chromodorididae that is known to incorporate O-PBDEs, rather than terpenes, in the mantle where the metabolites may play a putative role in chemical defense. The extract ofM. magnificawas tested in a brine shrimp lethality assay and exhibited an LD50of 58 μg/mL.
authors: School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia 4072, QLD, Australia. ariyanti.dewi@uqconnect.edu.au.|Research and Development Center for Marine and Fisheries Product Competitiveness and Biotechnology, Ministry of Marine Affairs and Fisheries, Jakarta 10260, Indonesia. ariyanti.dewi@uqconnect.edu.au.
authors: Ariyanti S
authors: AS
authors: Dewi
authors: School of Biological Sciences, The University of Queensland, St. Lucia 4072, QLD, Australia. k.cheney@uq.edu.au.
authors: Karen L
authors: KL
authors: Cheney
authors: School of Biological Sciences, The University of Queensland, St. Lucia 4072, QLD, Australia. holly.urquhart@uqconnect.edu.au.
authors: Holly H
authors: HH
authors: Urquhart
authors: School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia 4072, QLD, Australia. j.blanchfield@uq.edu.au.
authors: Joanne T
authors: JT
authors: Blanchfield
authors: School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia 4072, QLD, Australia. m.garson@uq.edu.au.
authors: Mary J
authors: MJ
authors: Garson
mesh_terms: D000818:Animals; D001156:Artemia / Q000187:drug effects; D005247:Feeding Behavior / Q000187:drug effects; D005399:Fishes; D049851:Gastropoda / Q000737:chemistry*; D055768:Halogenated Diphenyl Ethers / Q000737:chemistry* / Q000378:metabolism*; D007928:Lethal Dose 50; D011075:Polybrominated Biphenyls / Q000737:chemistry* / Q000378:metabolism*; D011793:Queensland; D013729:Terpenes / Q000378:metabolism; D014874:Water Pollutants, Chemical
chemical_list: D055768:Halogenated Diphenyl Ethers; D011075:Polybrominated Biphenyls; D013729:Terpenes; D014874:Water Pollutants, Chemical
keywords: Chromodorididae; Miamira magnifica; Miamira miamirana; nudibranch; oxy-polybrominated diphenyl ethers