title: Access to Thiazole via Copper-Catalyzed [3+1+1]-Type Condensation Reaction under Redox-Neutral Conditions.
abstract: A new strategy for thiazoles via copper-catalyzed [3+1+1]-type condensation reaction from oximes, anhydrides and potassiumthiocyanate (KSCN) is developed herein. The transformation has good functional group tolerance and various thiazoles were formed smoothly in good to excellent yields under mild reaction conditions. This process involves copper-catalyzed N-O/C-S bond cleavages, activation of vinyl sp2C-H bond, and C-S/C-N bond formations which are under redox-neutral conditions as well as operational simplicity.
authors: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors: Xiaodong
authors: X
authors: Tang
authors: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors: Jidan
authors: J
authors: Yang
authors: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors: Zhongzhi
authors: Z
authors: Zhu
authors: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors: Meifang
authors: M
authors: Zheng
authors: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors: Wanqing
authors: W
authors: Wu
authors: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors: Huanfeng
authors: H
authors: Jiang