title: Clinical predictors of early acute respiratory distress syndrome in trauma patients.
abstract: BACKGROUND
  The objectives of this study were to examine the incidence and severity of early acute respiratory distress syndrome (ARDS) according to the Berlin Definition and to identify risk factors associated with the development of early post-traumatic ARDS.
  
  
  METHODS
  A 2.5-year retrospective database of adult trauma patients who required mechanical ventilation for greater than 48 hours at a level 1 trauma center was analyzed for variables predictive of early (<48 hours after injury), mild, moderate, and severe ARDS and in-hospital mortality.
  
  
  RESULTS
  Of 305 patients, 59 (19.3%) developed early ARDS: mild, 27 (45.8%); moderate, 26 (44.1%); and severe, 6 (10.1%). Performance of an emergent thoracotomy, blunt mechanism, and fresh frozen plasma administration were independently associated with the development of early ARDS. ARDS was not predictive of mortality.
  
  
  CONCLUSIONS
  Trauma patients with blunt mechanism, who receive fresh frozen plasma, or undergo thoracotomy, are at risk of developing early ARDS.
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: Michael P
authors: MP
authors: O'Leary
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: Jessica A
authors: JA
authors: Keeley
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: Arthur
authors: A
authors: Yule
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: Caitlyn
authors: C
authors: Suruki
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: David S
authors: DS
authors: Plurad
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: Ashkan
authors: A
authors: Moazzez
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: Angela L
authors: AL
authors: Neville
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA.
authors: Brant A
authors: BA
authors: Putnam
authors: Harbor-UCLA Medical Center, Department of Surgery, 1000 West Carson Street Box 461, Torrance, CA 90502, USA. Electronic address: dekim@dhs.lacounty.gov.
authors: Dennis Y
authors: DY
authors: Kim
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D014193:Trauma Centers; D014947:Wounds and Injuries / Q000150:complications* / Q000401:mortality / Q000628:therapy
keywords: Acute respiratory distress syndrome; Predictors; Trauma