title: Advances in Radiotherapy Management of Esophageal Cancer.
abstract: Radiation therapy (RT) as part of multidisciplinary oncologic care has been marked by profound advancements over the past decades. As part of multimodality therapy for esophageal cancer (EC), a prime goal of RT is to minimize not only treatment toxicities, but also postoperative complications and hospitalizations. Herein, discussion commences with the historical approaches to treating EC, including seminal trials supporting multimodality therapy. Subsequently, the impact of RT techniques, including three-dimensional conformal RT, intensity-modulated RT, and proton beam therapy, is examined through available data. We further discuss existing data and the potential for further development in the future, with an appraisal of the future outlook of technological advancements of RT for EC.
authors: Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA. vivek.verma@unmc.edu.
authors: Vivek
authors: V
authors: Verma
authors: Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. akmoreno@mdanderson.org.
authors: Amy C
authors: AC
authors: Moreno
authors: Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. shlin@mdanderson.org.
authors: Steven H
authors: SH
authors: Lin
keywords: esophageal cancer; intensity-modulated radiation therapy; proton beam therapy; three-dimensional conformal radiation therapy; trimodality therapy