title: The evaluation of non-ischemic dilated cardiomyopathy with T1 mapping and ECV methods using 3T cardiac MRI.
abstract: OBJECTIVE
  The aim of this study was to examine the correlation between ventricular function and the extracellular volume fraction (ECV) in patients with non-ischemic dilated cardiomyopathy (NIDCM) using 3.0 T magnetic resonance imaging (MRI). We also hypothesized that native T1 and ECV values would be increased in patients with NIDCM, independent of the left ventricular ejection fraction (LVEF). The findings of our study could lead to further studies of the follow-up protocols.
  
  
  METHODS
  In total, 53 consecutive dilated cardiomyopathy patients who had undergone cardiac MRI were functionally evaluated and underwent tissue characterization.
  
  
  RESULTS
  The mean native T1 value was 1235 ± 10 ms, and the mean ECV value was 35.4 ± 2.7% in the myocardia. The LVEF values ranged from 29 to 44%. No significant correlations were observed between functional analysis measurements and native T1 or ECV values.
  
  
  CONCLUSIONS
  Our results showed that myocardial fibrosis is unrelated to cardiac functional findings in NIDCM patients. Therefore, we propose that these patients should be evaluated using MRI and tissue characterization techniques, in addition to cardiac functional analysis.
authors: Department of Radiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Radyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey. ayseyazici@yahoo.com.
authors: Cemile Ayşe
authors: http://orcid.org/0000-0002-9442-4802
authors: CA
authors: Görmeli
authors: Department of Radiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Radyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey.
authors: Zeynep Maraş
authors: ZM
authors: Özdemir
authors: Department of Radiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Radyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey.
authors: Ayşegül Sağır
authors: AS
authors: Kahraman
authors: Department of Cardiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Kardiyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey.
authors: Jülide
authors: J
authors: Yağmur
authors: Department of Cardiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Kardiyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey.
authors: Ramazan
authors: R
authors: Özdemir
authors: Department of Biostatistics, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Biyoistatistik Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey.
authors: Cemil
authors: C
authors: Çolak
mesh_terms: D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D018450:Disease Progression; D005260:Female; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D013997:Time Factors; D016277:Ventricular Function, Left
keywords: Cardiac magnetic resonance imaging; Extracellular volume fraction; Left ventricular ejection fraction; Myocardial fibrosis; Nonischemic dilated cardiomyopathy; T1 mapping