title: A sub-minute electrophoretic method for simultaneous determination of naphazoline and zinc.
abstract: This paper reports for the first time, a method for simultaneous determination of naphazoline (NPZ) and zinc (Zn) using an analytical separation technique (capillary electrophoresis with capacitively coupled contactless conductivity detection -CE-C4D). A single run is possible every 55s (sampling rate=65h-1). The separation by CE-C4D was achieved on a fused silica capillary (50cm length - 10cm effective, 50μm i.d.) with a background electrolyte (BGE) composed by 20mmolL-1of 2-(morpholin-4-yl)ethane-1-sulfonic acid (MES) and 20mmolL-1of histidine (HIS) (pH 6.0). Detection limits were estimated at 20 and 30μmolL-1and recovery values for spiked samples were 98 and 102% for NPZ and Zn, respectively. The developed procedure was compared to HPLC (NPZ) and FAAS (Zn) and no statistically significant differences were observed (95% confidence level).
authors: Instituto de Química, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, 13400-970, Uberlândia, MG, Brazil.
authors: Michelle M A C
authors: MM
authors: Ribeiro
authors: Instituto de Química, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, 13400-970, Uberlândia, MG, Brazil.
authors: Thiago C
authors: TC
authors: Oliveira
authors: Instituto de Química, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, 13400-970, Uberlândia, MG, Brazil.
authors: Alex D
authors: AD
authors: Batista
authors: Instituto de Química, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, 13400-970, Uberlândia, MG, Brazil.
authors: Rodrigo A A
authors: RA
authors: Muñoz
authors: Instituto de Química, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, 13400-970, Uberlândia, MG, Brazil. Electronic address: emrichter@ufu.br.
authors: Eduardo M
authors: EM
authors: Richter
mesh_terms: D002851:Chromatography, High Pressure Liquid; D025802:Electric Capacitance; D004553:Electric Conductivity; D004573:Electrolytes / Q000737:chemistry; D019075:Electrophoresis, Capillary / Q000379:methods*; D057230:Limit of Detection; D009278:Naphazoline / Q000032:analysis*; D015032:Zinc / Q000032:analysis*
chemical_list: D004573:Electrolytes; D009278:Naphazoline; D015032:Zinc
keywords: Capillary electrophoresis; Contactless conductivity detection; Fast separation; Organic and inorganic compounds; Short column