title: [Heart transplantation for the treatment of isolated left ventricular myocardial noncompaction. First case in Mexico].
abstract: BACKGROUND
  Myocardial noncompaction of the left ventricle is a congenital cardiomyopathy characterised by left ventricular hypertrabeculation and prominent intertrabecular recesses. The incidence ranges from 0.15% to 2.2%. Clinical manifestations include heart failure, arrhythmias, and stroke. Prognosis is fatal in most cases. Heart transplantation is a therapeutic option for this cardiomyopathy, and few had been made worldwide.
  
  
  METHODS
  The case is presented of a 20 year-old male with noncompacted myocardium of the left ventricle, who had clinical signs of heart failure. His functional class was IV on the New York Heart Association scale. He was successfully transplanted. Its survival to 15 months is optimal in class I New York Heart Association, and endomyocardial biopsies have been reported without evidence of acute rejection.
  
  
  CONCLUSIONS
  It is concluded that heart transplantation modified the natural history and improved survival in patients with this congenital heart disease.
authors: Clínica de Trasplante de Órganos Torácicos. Unidad Médica de Alta Especialidad, Hospital General Gaudencio González Garza, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors: Hugo Jesús
authors: HJ
authors: Zetina-Tun
authors: Dirección General. Unidad Médica de Alta Especialidad, Hospital General Gaudencio González Garza, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Ciudad de México, México. Electronic address: gcareaga3@gmail.com.
authors: Guillermo
authors: G
authors: Careaga-Reyna
authors: Departamento de Cirugía Cardiotorácica. Unidad Médica de Alta Especialidad, Hospital General Gaudencio González Garza, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors: José
authors: J
authors: Galván-Díaz
authors: Departamento de Anatomía Patológica, Unidad Médica de Alta Especialidad, Hospital de Especialidades Antonio Fraga Mouret, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors: Magdalena
authors: M
authors: Sánchez-Uribe
mesh_terms: D002317:Cardiovascular Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004452:Echocardiography; D016027:Heart Transplantation; D006801:Humans; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D055815:Young Adult
chemical_list: D002317:Cardiovascular Agents
keywords: Cardiopatía congénita; Congenital cardiomyopathy; Heart failure; Heart transplantation; Insuficiencia cardiaca; Miocardio no compactado del ventrículo izquierdo; Myocardial noncompaction of the left ventricle; Trasplante cardiaco