title: [Clinical features of malignant tumor liver infiltration with liver failure as initial clinical manifestation: a single-center retrospective analysis of 9 cases].
abstract: Objective:To investigate the clinical features of patients with liver failure caused by tumor diffuse liver infiltration.Methods:A retrospective analysis was performed for the clinical data of 1008 patients with liver failure who were admitted to our hospital from July 2009 to December 2015. Among these patients, 9 had acute liver failure caused by liver metastasis of malignant tumor. Their clinical manifestations, laboratory markers, clinical progress, and outcome were observed, and the clinical features were summarized.Results:Such patients were manifested as liver enlargement and rapid clinical progression, and imaging examination showed stenosis due to external compression in the inferior vena cava. The patients might be easily misdiagnosed with Budd-Chiari syndrome and had a poor prognosis, with a mortality rate as high as 100%.Conclusion:As for the liver failure patients with unexplained liver enlargement, the possibility of liver metastasis of malignant tumors should be considered. Liver biopsy should be performed as early as possible before the deterioration of liver function, in order to facilitate the targeted therapy for the primary tumor.
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: J P
authors: JP
authors: Liu
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: H B
authors: HB
authors: Ning
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: K
authors: K
authors: Li
authors: Department of Pathology, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: M Y
authors: MY
authors: Zhang
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: W
authors: W
authors: Li
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: C S
authors: CS
authors: Mao
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: H W
authors: HW
authors: Wu
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: Y
authors: Y
authors: Kang
authors: Department of Infectious Disease, Henan Province People's Hospital, Zhengzhou 450003, China.
authors: J
authors: J
authors: Shang
mesh_terms: D000328:Adult; D006502:Budd-Chiari Syndrome; D005260:Female; D006529:Hepatomegaly; D006801:Humans; D017093:Liver Failure; D017114:Liver Failure, Acute; D008113:Liver Neoplasms; D008297:Male; D012189:Retrospective Studies; D014682:Vena Cava, Inferior