title: RNA Binding: Getting Specific about Specificity.
abstract: Sequence-specific nucleic acid binding proteins do not recognize one sequence out of all possibilities; rather, they bind to many sequences with a range of affinities. In this issue of Cell Chemical Biology, Lin et al. (2016), describe the entire landscape of affinities between different RNA molecules and an RNA-binding protein, thus providing a comprehensive description of the factors affecting specificity.
authors: National Heart, Lung and Blood Institute, 50 South Drive, MSC 8012, Bethesda, MD 20892, USA. Electronic address: adrian.ferre@nih.gov.
authors: Adrian R
authors: AR
authors: Ferré-D'Amaré
mesh_terms: D012313:RNA; D016601:RNA-Binding Proteins; D043262:Ribonuclease P
chemical_list: D016601:RNA-Binding Proteins; D012313:RNA; D043262:Ribonuclease P