title: Multifunctional Mesoporous Carbon Capsules and their Robust Coatings for Encapsulation of Actives: Antimicrobial and Anti-bioadhesion Functions.
abstract: We present the synthesis and applications of multifunctional hollow porous carbon spheres with well-ordered pore architecture and ability to encapsulate functional nanoparticles. In the present work, the applications of hollow mesoporous carbon capsules (HMCCs) are illustrated in two different contexts. In the first approach, the hollow capsule core is used to encapsulate silver nanoparticles to impart antimicrobial characteristics. It is shown that silver-loaded HMCCs (concentration ∼100 μg/mL) inhibit the growth and multiplication of bacterial colonies of Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) up to 96% and 83%, respectively. In the second part, the fabrication of hierarchical micro- and nanostructured superhydrophobic coatings of HMCCs (without encapsulation with silver nanoparticles) is evaluated for anti-bioadhesion properties. Studies of protein adsorption and microorganism and platelet adhesion have shown a significant reduction (up to 100%) for the HMCC-based superhydrophobic surfaces compared with the control surfaces. Therefore, this unique architecture of HMCCs and their coatings with the ability to encapsulate functional materials make them a promising candidate for a variety of applications.
authors: Department of Chemical Engineering and Centre of Nanosciences, Indian Institute of Technology Kanpur , Kanpur-208016, India.
authors: Gargi
authors: G
authors: Mishra
authors: Department of Chemical Engineering and Centre of Nanosciences, Indian Institute of Technology Kanpur , Kanpur-208016, India.
authors: Nitesh
authors: N
authors: Mittal
authors: Department of Chemical Engineering and Centre of Nanosciences, Indian Institute of Technology Kanpur , Kanpur-208016, India.
authors: Ashutosh
authors: A
authors: Sharma
mesh_terms: D000900:Anti-Bacterial Agents; D002214:Capsules; D002244:Carbon / Q000737:chemistry*; D053768:Metal Nanoparticles; D016062:Porosity; D012834:Silver
chemical_list: D000900:Anti-Bacterial Agents; D002214:Capsules; D012834:Silver; D002244:Carbon
keywords: anti-bioadhesion; antimicrobial; mesoporous carbon capsules; silver encapsulation; superhydrophobic