title: DETECTION OF CTX-M GENE ANTIBIOTICS RESISTANCE IN KLEBSIELLA PNEUMONIA ISOLATES OF HOSPITALS IN ADJARA (GEORGIA).
abstract: Research describing the epidemiology of antibiotic resistant microbes is vital to the proactive development of new antimicrobial agents. In the last years, CTX-M extended-spectrum β-lactamases (ESBLs) have emerged worldwide and have replaced classical TEM and SHV-type ESBLs in many countries. CTX-M-15 is currently the most frequent, with a pandemic distribution, and its rapid spread is facilitated by incorporation of resistance genes in mobile genetic elements. The ESBL is efficacious in Gram-negative bacteria and thus closely associated with nosocomial environments, often colonizing the intestines, particularly in older and dependent patients. Little is known about the CTX-M ESBLs among Klebsiella pneumonia in Adjara. Our paper describes the detected and characterized ESBLs among Klebsiella pneumonia isolates from patients in two different hospitals in Adjara.
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia; University of Porto - Pharmacy Faculty, Department of Microbiology, Portugal; Health Superior Institute of Alto Ave, Portugal; Adjara National Center for Disease Control and Public Health, Batumi, Georgia; Eliava Institute of Bacteriophage, Tbilisi, Georgia.
authors: T
authors: T
authors: Koiava
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia; University of Porto - Pharmacy Faculty, Department of Microbiology, Portugal; Health Superior Institute of Alto Ave, Portugal; Adjara National Center for Disease Control.
authors: D
authors: D
authors: Gonçalves
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia; University of Porto - Pharmacy Faculty, Department of Microbiology, Portugal; Health Superior Institute of Alto Ave, Portugal; Adjara National Center for Disease Control.
authors: J
authors: J
authors: Palmeira
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia; University of Porto - Pharmacy Faculty, Department of Microbiology, Portugal; Health Superior Institute of Alto Ave, Portugal; Adjara National Center for Disease Control.
authors: K
authors: K
authors: Arobelidze
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia; University of Porto - Pharmacy Faculty, Department of Microbiology, Portugal; Health Superior Institute of Alto Ave, Portugal; Adjara National Center for Disease Control.
authors: M
authors: M
authors: Tediashvili
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia; University of Porto - Pharmacy Faculty, Department of Microbiology, Portugal; Health Superior Institute of Alto Ave, Portugal; Adjara National Center for Disease Control.
authors: L
authors: L
authors: Akhvlediani
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia; University of Porto - Pharmacy Faculty, Department of Microbiology, Portugal; Health Superior Institute of Alto Ave, Portugal; Adjara National Center for Disease Control.
authors: H
authors: H
authors: Ferreira
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003428:Cross Infection / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D005798:Genes, Bacterial; D005846:Georgia (Republic); D006761:Hospitals; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D018440:beta-Lactam Resistance / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases