title: Informed Consent: A Clinical Trials Perspective
abstract: The primary goal of the thousands of registered trials in cancer research is to extend survival. With evaluation of efficacy, safety, and tolerability, healthcare providers must ensure that the principles described in the Belmont Report are upheld and that patients are truly informed when signing a consent form. In this article, two cases are highlighted, and reasons for participating in clinical trials are discussed. Challenges, such as healthcare literacy, patients' dedication to their healthcare providers, and choosing between multiple trials, are also explored.
authors: College of Nursing, New York University in New York.
authors: Marilyn J
authors: 0000-0002-9561-6144
authors: MJ
authors: Hammer
authors: Rockefeller University.
authors: Patricia
authors: P
authors: Eckardt
authors: Memorial Sloan Kettering Cancer Center.
authors: Margaret
authors: M
authors: Barton-Burke
mesh_terms: D000293:Adolescent; D002986:Clinical Trials as Topic / Q000592:standards*; D005260:Female; D017408:Guidelines as Topic; D006801:Humans; D007258:Informed Consent / Q000941:ethics* / Q000592:standards*; D008297:Male; D009369:Neoplasms / Q000451:nursing*; D015399:Nursing Research / Q000941:ethics* / Q000592:standards*; D009859:Oncology Nursing / Q000592:standards*
keywords: biology of cancer; ethics; genetics; nursing research