title: Beneficial Effects of UV-Radiation: Vitamin D and beyond.
abstract: Aside from its well-known effects on bone and mineral metabolism, vitamin D may also play an important role in extra-skeletal processes like immunologic diseases, cancer, or cardiovascular diseases. Even though meta-analyses showed that vitamin D supplementation reduces fractures, falls, and overall mortality, its potential benefits did not find universal acclaim. Several health care authorities published Recommended Dietary Allowances (RDAs) for vitamin D, most of them ranging from 600 to 800 international units (IU) per day, corresponding to a serum level of 25-hydroxyvitamin D of at least 20 ng/mL (50 nmol/L). However, studies conducted in the general population revealed a much lower overall intake of vitamin D than the proposed RDAs. Thus, strategies to increase the vitamin D intake in the general population, e.g., food fortification or vitamin D supplementation, are needed to match the existing evidence and recommendations. Therefore, several currently ongoing projects aim to investigate the effect of vitamin D supplementation in the general population and try to establish food-based solutions to improve vitamin D status.
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. christian.trummer@medunigraz.at.
authors: Christian
authors: C
authors: Trummer
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. marlene.pandis@medunigraz.at.
authors: Marlene
authors: M
authors: Pandis
authors: Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. nicolas.verheyen@medunigraz.at.
authors: Nicolas
authors: N
authors: Verheyen
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. martin.gruebler@gmx.net.|Department of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, Freiburgstrasse 8, Bern 3010, Switzerland. martin.gruebler@gmx.net.
authors: Martin R
authors: MR
authors: Grübler
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. martin.gaksch@gmail.com.
authors: Martin
authors: M
authors: Gaksch
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. barbara.obermayer@medunigraz.at.
authors: Barbara
authors: B
authors: Obermayer-Pietsch
authors: Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. andreas.tomaschitz@medunigraz.at.|Bad Gleichenberg Clinic, Schweizereiweg 4, Bad Gleichenberg 8344, Austria. andreas.tomaschitz@medunigraz.at.
authors: Andreas
authors: A
authors: Tomaschitz
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. thomas.pieber@medunigraz.at.
authors: Thomas R
authors: TR
authors: Pieber
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. stefan.pilz@medunigraz.at.
authors: Stefan
authors: S
authors: Pilz
authors: Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria. verena.schwetz@medunigraz.at.
authors: Verena
authors: V
authors: Schwetz
mesh_terms: D000058:Accidental Falls; D001842:Bone and Bones; D019587:Dietary Supplements; D005527:Food, Fortified; D006801:Humans; D014466:Ultraviolet Rays; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000378:metabolism / Q000528:radiation effects; D014808:Vitamin D Deficiency / Q000097:blood
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: 25(OH)D; UV-radiation; review; vitamin D