title: [Renal denervation as treatment option for hypertension].
abstract: The rationale behind catheter-based renal denervation is that afferent and efferent renal nerves play a role in the pathogenesis and maintenance of high blood pressure, and that this can be prevented by blocking the function of the renal nerves. Since the introduction of catheter-based renal denervation, several observational and a small number of randomised controlled trials have been conducted. The available evidence does not allow for a definitive conclusion regarding its efficacy. There have been no serious side-effects reported. The development of this treatment concept has not been finalised; new trials have just commenced or will start in the near future.
authors: Universitair Medisch Centrum Utrecht, Utrecht.
authors: P J
authors: PJ
authors: Blankestijn
authors: M L
authors: ML
authors: Bots
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D018849:Controlled Clinical Trials as Topic; D006801:Humans; D006973:Hypertension / Q000503:physiopathology / Q000601:surgery*; D007668:Kidney / Q000294:innervation*; D013562:Sympathectomy / Q000379:methods*