title: The Prevalence ofS. aureusSkin and Soft Tissue Infections in Patients with Pemphigus.
abstract: Pemphigus vulgaris are autoimmune blistering diseases that may result in significant morbidity and death. Immunosuppressive therapy of pemphigus vulgaris would predispose the patients to infections. The aim of this study was to assess the prevalence ofS. aureusinfection andPVLgene in patients with pemphigus admitted to dermatology clinic.Materials and Methods. This descriptive study was conducted on 196 pemphigus vulgaris patients (119 males, 77 females) admitted to dermatology clinic between 2014 and 2015. In this study, the diagnosis of pemphigus vulgaris was made by histology, immunofluorescence pattern of perilesional skin, and indirect immunofluorescence testing of serum. Data were collected through a questionnaire.Results. 59.1% of pemphigus vulgaris patients hadS. aureusinfection. 49 out of 116 were methicillin-resistant.PVLgene was detected in 25 out of 116S. aureuspositive patients.Conclusion. This is the first report ofS. aureusinfection in pemphigus patients in Iran. More than forty percent of isolates were methicillin-resistantS. aureus.PVLgene carried by methicillin-resistantS. aureuswas high in this study.
authors: Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
authors: Zeinab
authors: 0000-0003-2071-7060
authors: Z
authors: Fagheei Aghmiyuni
authors: Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
authors: Ahmad
authors: 0000-0002-7478-8895
authors: A
authors: Khorshidi
authors: Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran; Anatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran.
authors: Rezvan
authors: 0000-0001-7641-1998
authors: R
authors: Moniri
authors: Razi Hospital, Tehran University of Medical Sciences, Tehran 11996 63911, Iran.
authors: Tahereh
authors: T
authors: Soori
authors: Department of Statistics, Health Faculty, Kashan University of Medical Sciences, Kashan, Iran.
authors: Seyed Gholam Abbas
authors: SG
authors: Musavi