title: [Obesity and obstructive sleep apnea in children].
abstract: Obesity, along with hypertrophy of the adenoids and the tonsils, represents one of the major risk factors for obstructive sleep apnea (OSA) in children. Obesity is associated with an increase in the prevalence and the severity of OSA and is a major factor in the persistence and aggravation of OSA over time. Neurocognitive dysfunction and abnormal behavior are the most important and frequent end-organ morbidities associated with OSA in children. Other deleterious consequences such as cardiovascular stress and metabolic syndrome are less common in children than in adults with OSA. Defining the exact role of obesity in OSA-associated end-organ morbidity in children is difficult because of the complex and multidimensional interactions between sleep in general, OSA, obesity, and metabolic dysregulation. This may explain why obesity itself has not been shown to be associated with a significant increase in OSA-associated end-organ morbidity. Obesity is linked to a decreased treatment efficacy and, in particular, of adenotonsillectomy. Peri- and postoperative complications are more common and more severe in obese children as compared with normal-weight controls. Continuous positive airway pressure (CPAP) is frequently needed, but compliance with CPAP is less optimal in obese children than in non-obese children. In conclusion, obesity represents a major public health problem worldwide; its prevention is one of the most efficient tools for decreasing the incidence and the morbidity associated with OSA in children.
authors: Unité de ventilation noninvasive et du sommeil de l'enfant, hôpital universitaire Necker-Enfants-Malades, AP-HP, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes, Paris, France; Équipe 13, Inserm U955, 94000 Créteil, France.
authors: A
authors: A
authors: Amaddeo
authors: Unité de ventilation noninvasive et du sommeil de l'enfant, hôpital universitaire Necker-Enfants-Malades, AP-HP, 149, rue de Sèvres, 75015 Paris, France.
authors: L
authors: L
authors: de Sanctis
authors: Unité de ventilation noninvasive et du sommeil de l'enfant, hôpital universitaire Necker-Enfants-Malades, AP-HP, 149, rue de Sèvres, 75015 Paris, France.
authors: J
authors: J
authors: Olmo Arroyo
authors: Centre du sommeil de l'Hôtel-Dieu, 75004 Paris, France; Hôpital pédiatrique de rééducation de Bullion, 78830 Bullion, France.
authors: J-P
authors: JP
authors: Giordanella
authors: Polyclinique du Tondu et clinique du sommeil, hôpital Pellegrin Bordeaux, 33000 Bordeaux, France.
authors: P-J
authors: PJ
authors: Monteyrol
authors: Unité de ventilation noninvasive et du sommeil de l'enfant, hôpital universitaire Necker-Enfants-Malades, AP-HP, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes, Paris, France; Équipe 13, Inserm U955, 94000 Créteil, France. Electronic address: brigitte.fauroux@aphp.fr.
authors: B
authors: B
authors: Fauroux
mesh_terms: D000233:Adenoidectomy; D002648:Child; D045422:Continuous Positive Airway Pressure; D006801:Humans; D063766:Pediatric Obesity / Q000150:complications*; D011183:Postoperative Complications; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000209:etiology* / Q000628:therapy; D014068:Tonsillectomy; D015431:Weight Loss