title: Secondary Merkel Cell Carcinoma Arising From a Graft Donor Site.
abstract: Merkel cell carcinoma (MCC) is a highly aggressive cutaneous neuroendocrine tumour that is increasing in incidence. We report a case of a 92-year-old white man on long-term immunosuppression for temporal arteritis who presented with a Merkel cell tumour on his left cheek. A wide local excision was performed and the defect was reconstructed with a full-thickness skin graft. Four years later, the patient re-presented with a Merkel cell tumour arising from the right supraclavicular donor site. To our knowledge, this is the first report of a recurrence of MCC into a donor site. This has important implications as a reminder of planning fresh surgical instruments and needle inoculation for reconstruction if there is any clinical suspicion of MCC to prevent iatrogenic spread.
authors: 1 Lister Hospital, East & North Hertfordshire NHS Trust, Stevenage, UK.
authors: Fatima
authors: F
authors: Aloraifi
authors: 1 Lister Hospital, East & North Hertfordshire NHS Trust, Stevenage, UK.
authors: Stephen
authors: S
authors: Mulgrew
authors: 1 Lister Hospital, East & North Hertfordshire NHS Trust, Stevenage, UK.
authors: Nick K
authors: NK
authors: James
mesh_terms: D000369:Aged, 80 and over; D015266:Carcinoma, Merkel Cell / Q000601:surgery*; D002610:Cheek; D005153:Facial Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D009333:Neck; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000628:therapy; D012878:Skin Neoplasms / Q000601:surgery*; D016038:Skin Transplantation; D060053:Transplant Donor Site / Q000473:pathology*
keywords: Merkel cell tumour; donor site morbidity; skin graft; tumour seeding