title: Current concepts for the diagnosis and management of eosinophilic granuloma of bone.
abstract: This review summarizes current concepts in the diagnosis and management of the patients with eosinophilic granuloma. Given the benign biology, the clinical course, and the pediatric group of patients that this condition more commonly affects, a treatment approach that carries a lower risk of complications while ensuring a successful cure is desirable. Variable treatment options have been reported with satisfactory results and a recurrence rate of less than 20 %. In this setting, symptomatic lesions that are accessible in the spine or the extremities may be treated with intralesional methylprednisolone injection after tissue biopsy for histological diagnosis.
authors: Department of Orthopedics, University of Bologna, Istituto Ortopedico Rizzoli, Via Pupilli, 40136, Bologna, Italy. andrea.angelini83@yahoo.it.
authors: Andrea
authors: A
authors: Angelini
authors: First Department of Orthopaedics, Athens University Medical School, ATTIKON University Hospital, Athens, Greece.
authors: Andreas F
authors: AF
authors: Mavrogenis
authors: Department of Radiology and Interventional Angiographic Radiology, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors: Eugenio
authors: E
authors: Rimondi
authors: Department of Radiology and Interventional Angiographic Radiology, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors: Giuseppe
authors: G
authors: Rossi
authors: Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy.
authors: Pietro
authors: P
authors: Ruggieri
mesh_terms: D001706:Biopsy; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D003131:Combined Modality Therapy; D019468:Disease Management; D004803:Eosinophilic Granuloma / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Bone tumors; Eosinophilic granuloma; Extremities; Methylprednisolone injection; Spine