title: Increasing observation rates in low-risk pediatric immune thrombocytopenia using a standardized clinical assessment and management plan (SCAMP®).
abstract: An observational approach is recommended in newly diagnosed children with immune thrombocytopenia (ITP) at low risk of bleeding; however, there is no standard definition of risk. A standardized clinical assessment and management plan (SCAMP®), a modifiable practice guideline, was implemented and revised (SCAMP-1 and SCAMP-2) and applied to 71 newly diagnosed patients with ITP. The Buchanan and Adix bleeding score guided treatment and was modified by stratifying by low- and high-risk grade 3 bleeding in SCAMP-2. Observation rates increased from 40% to 74% from SCAMP-1 to SCAMP-2 (P < 0.05) with no bleeding complications. We propose a modified bleeding score that increased observation rates in low-risk patients with ITP.
authors: Pediatric Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
authors: Michelle L
authors: ML
authors: Schoettler
authors: Institute for Relevant Clinical Data Analytics, Boston, Massachusetts.
authors: Dionne
authors: D
authors: Graham
authors: Program for Patient Safety and Quality, Boston Children's Hospital, Boston, Massachusetts.
authors: Wen
authors: W
authors: Tao
authors: Program for Patient Safety and Quality, Boston Children's Hospital, Boston, Massachusetts.
authors: Margaret
authors: M
authors: Stack
authors: Program for Patient Safety and Quality, Boston Children's Hospital, Boston, Massachusetts.
authors: Elaine
authors: E
authors: Shu
authors: Institute for Relevant Clinical Data Analytics, Boston, Massachusetts.
authors: Lauren
authors: L
authors: Kerr
authors: Pediatric Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
authors: Ellis J
authors: EJ
authors: Neufeld
authors: Pediatric Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
authors: Rachael F
authors: RF
authors: Grace
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019468:Disease Management; D005260:Female; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D010347:Patient Care Planning; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome
keywords: bleeding; guideline; immune thrombocytopenia; pediatrics; treatment