title: Diabetic peripheral neuropathy and prevalence of erectile dysfunction in Japanese patients aged <65 years with type 2 diabetes mellitus: The Dogo Study.
abstract: Only limited epidemiological evidence exists regarding the relationship between diabetic neuropathy and erectile dysfunction (ED) among Japanese patients with type 2 diabetes mellitus. To investigate the relationship between diabetic neuropathy and ED among Japanese patients with type 2 diabetes mellitus, a multicenter cross-sectional study was conducted in 287 male Japanese patients with type 2 diabetes mellitus, age (19-65 years). Diabetic neuropathy was diagnosed if the patients showed two or more of the following three characteristics: neuropathic symptoms, decreased or disappeared Achilles tendon reflex and/or abnormal vibration perception. ED, moderate to severe ED, and severe ED were defined as present when a subject had a Sexual Health Inventory for Men score <22, <12 and <8, respectively. The prevalence values of diabetic neuropathy and severe ED were 47.0 and 39.0%, respectively. Diabetic neuropathy was independently positively associated with severe ED, but not ED and moderate ED: the adjusted odds ratio was 1.90 (95% confidence interval: 1.08-3.38). No relationships were found between diabetic retinopathy or diabetic nephropathy and ED. Diabetic neuropathy is positively associated with severe erectile dysfunction among Japanese type 2 diabetes mellitus patients aged <65 years.
authors: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.|Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Shitsukawa, Toon, Japan.
authors: S
authors: S
authors: Furukawa
authors: Department of Internal Medicine, Yawatahama General City Hospital, Yawatahama, Japan.
authors: T
authors: T
authors: Sakai
authors: Department of Internal Medicine, Matsuyama Shimin Hospital, Otemachi, Matsuyama, Japan.
authors: T
authors: T
authors: Niiya
authors: Department of Internal Medicine, Saiseikai Matsuyama Hospital, Matsuyama, Japan.
authors: H
authors: H
authors: Miyaoka
authors: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.
authors: T
authors: T
authors: Miyake
authors: Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.
authors: S
authors: S
authors: Yamamoto
authors: Department of Public Health, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan.
authors: K
authors: K
authors: Maruyama
authors: Department of Internal Medicine, Ehime Prefectural Central Hospital, Matsuyama, Japan.
authors: T
authors: T
authors: Ueda
authors: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.|Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.
authors: H
authors: H
authors: Senba
authors: Department of Internal Medicine, Matsuyama Shimin Hospital, Otemachi, Matsuyama, Japan.
authors: Y
authors: Y
authors: Todo
authors: Department of Internal Medicine, Saiseikai Saijo Hospital, Saijo, Japan.
authors: M
authors: M
authors: Torisu
authors: Department of Internal Medicine, Ehime Niihama Hospital, Niihama, Japan.
authors: H
authors: H
authors: Minami
authors: Department of Internal Medicine, Saiseikai Imabari Hospital, Imabari, Japan.
authors: M
authors: M
authors: Onji
authors: Department of Public Health, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan.
authors: T
authors: T
authors: Tanigawa
authors: Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.
authors: B
authors: B
authors: Matsuura
authors: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.
authors: Y
authors: Y
authors: Hiasa
authors: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Japan.|Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Shitsukawa, Toon, Japan.
authors: Y
authors: Y
authors: Miyake
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003929:Diabetic Neuropathies / Q000453:epidemiology*; D007172:Erectile Dysfunction / Q000453:epidemiology*; D006801:Humans; D007564:Japan; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010410:Penile Erection; D011446:Prospective Studies; D012307:Risk Factors; D057566:Self Report; D012720:Severity of Illness Index; D055815:Young Adult