title: An Approach to Optically Pure Bridging Chiral p-tert-Butylcalix[4]arenes through a Homologous Anionic Ortho-Fries Rearrangement.
abstract: A novel efficient approach to optically pure bridging chiral calix[4]arenes through a homologous anionic ortho-Fries rearrangement of inherently chiral calix[4]arenes was presented for the first time. As a result, two pairs of N,N'-dimethylformamidyl-substituted bridging chiral p-tert-butylcalix[4]arene enantiomers were facilely obtained. Their absolute configurations were determined through ROESY analysis, ECD comparison, and X-ray crystallographic analysis.
authors: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University , 300070 Tianjin, People's Republic of China.
authors: Wen-Qiang
authors: WQ
authors: Xu
authors: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University , 300070 Tianjin, People's Republic of China.
authors: Wen-Shan
authors: WS
authors: Liu
authors: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University , 300070 Tianjin, People's Republic of China.
authors: Jiu-Xing
authors: JX
authors: Yan
authors: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University , 300070 Tianjin, People's Republic of China.
authors: Shi-Kun
authors: SK
authors: Ma
authors: School of Materials Science and Engineering, Sun Yat-Sen University , 510275 Guangzhou, People's Republic of China.
authors: Jing
authors: J
authors: Guo
authors: School of Materials Science and Engineering, Sun Yat-Sen University , 510275 Guangzhou, People's Republic of China.
authors: Jun-Min
authors: JM
authors: Liu
authors: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University , 300070 Tianjin, People's Republic of China.
authors: Run-Ling
authors: RL
authors: Wang
authors: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University , 300070 Tianjin, People's Republic of China.
authors: Shao-Yong
authors: SY
authors: Li