title: Genome sequences and annotation of two urinary isolates ofE. coli.
abstract: The genusEscherichiaincludes pathogens and commensals. Bladder infections (cystitis) result most often from colonization of the bladder by uropathogenicE. colistrains. In contrast, a poorly defined condition called asymptomatic bacteriuria results from colonization of the bladder withE. colistrains without symptoms. As part of an on-going attempt to identify and characterize the newly discovered female urinary microbiota, we report the genome sequences and annotation of two urinary isolates ofE. coli: one (E78) was isolated from a female patient who self-reported cystitis; the other (E75) was isolated from a female patient who reported that she did not have symptoms of cystitis. Whereas strain E75 is most closely related to an avian extraintestinal pathogen, strain E78 is a member of a clade that includes extraintestinal strains often found in the human bladder. Both genomes are uncommonly rich in prophages.
authors: Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, 2160 South First Avenue, Maywood, IL 60153 USA.
authors: Travis K
authors: TK
authors: Price
authors: Bioinformatics Program, Loyola University Chicago, Chicago, IL USA.
authors: Arya
authors: A
authors: Mehrtash
authors: Bioinformatics Program, Loyola University Chicago, Chicago, IL USA ; Department of Biology, Loyola University Chicago, Chicago, IL USA.
authors: Laurynas
authors: L
authors: Kalesinskas
authors: Department of Biology, Loyola University Chicago, Chicago, IL USA.
authors: Kema
authors: K
authors: Malki
authors: Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, 2160 South First Avenue, Maywood, IL 60153 USA.
authors: Evann E
authors: EE
authors: Hilt
authors: Bioinformatics Program, Loyola University Chicago, Chicago, IL USA ; Department of Biology, Loyola University Chicago, Chicago, IL USA ; Department of Computer Science, Loyola University Chicago, Chicago, IL USA.
authors: Catherine
authors: C
authors: Putonti
authors: Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, 2160 South First Avenue, Maywood, IL 60153 USA.
authors: Alan J
authors: AJ
authors: Wolfe
keywords: Bladder; Enterobacteriaceae; Escherichia coli; Lower urinary tract symptoms; UPEC; Urinary tract infection