title: Ochrobactrum anthropiKeratitis with Focal Descemet's Membrane Detachment and Intracorneal Hypopyon.
abstract: Purpose. To describe a unique case ofO. anthropikeratitis associated with a rare manifestation of Descemet's membrane detachment and intracorneal hypopyon and to discuss challenges in diagnosis and management.Methods. Best-corrected visual acuity was measured with Snellen letters. Corneal scrapings were performed and aerobic, viral, herpetic, acid-fast bacilli,Acanthamoeba,and fungal stains and cultures were obtained. Following evisceration, tissue was evaluated for histologic features and again stained for bacteria, mycobacteria,Acanthamoeba, fungi, and viral particles.Results. Initial presentation to our institute was notable for a corneal ulcer, focal Descemet's membrane detachment, and intracorneal hypopyon. Speciation of initial corneal scrapes revealedOchrobactrum anthropiand initial management included fortified tobramycin. Despite medical therapy, the patient developed a corneal perforation and required subsequent evisceration.Conclusion.O. anthropiis an emerging ocular pathogen that has not been previously reported in cases of keratitis. As this pathogen becomes increasingly recognized as a source of ocular infections, it is important to identify and treat aggressively to avoid vision-threatening disease.
authors: Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.
authors: Nandini
authors: N
authors: Venkateswaran
authors: Flaum Eye Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
authors: Rachel A F
authors: RA
authors: Wozniak
authors: Flaum Eye Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Center for Visual Science, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
authors: Holly B
authors: 0000-0001-6238-4044
authors: HB
authors: Hindman