title: Asymmetric Acute Motor Axonal Neuropathy With Unilateral Tongue Swelling Mimicking Stroke.
abstract: A 60-year-old man presented with acute onset of left hemiparesis and left hypoglossal nerve palsy with ipsilateral tongue swelling. He then progressed to tetraparesis in a few days. Cerebrospinal fluid showed cell protein dissociation. A nerve conduction study showed motor axonal neuropathy with sensory sparing. A subsequent blood test revealed anti-GD1b IgG antibody positivity. He was diagnosed to have acute motor axonal neuropathy (AMAN) and treated with a course of intravenous immunoglobulin with slow improvement. This is probably the first AMAN with asymmetrical presentation mimicking stroke reported in the literature in detail. The anti-GD1b IgG antibody is also not commonly associated with AMAN.
authors: Department of Medicine and Geriatrics, Tuen Mun Hospital, Tuen Mun, NT, Hong Kong.
authors: Man Sum
authors: MS
authors: Chi
authors: Shi Hon
authors: SH
authors: Ng
authors: Lok Yiu
authors: LY
authors: Chan
mesh_terms: D001323:Autoantibodies / Q000276:immunology; D003937:Diagnosis, Differential; D018450:Disease Progression; D005732:Gangliosides / Q000276:immunology; D020275:Guillain-Barre Syndrome / Q000276:immunology; D006801:Humans; D020437:Hypoglossal Nerve Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009431:Neural Conduction; D011115:Polyneuropathies / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D011782:Quadriplegia / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D020521:Stroke / Q000175:diagnosis*
chemical_list: D001323:Autoantibodies; D005732:Gangliosides; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; C033851:ganglioside, GD1b