title: Revised guideline for the diagnosis and treatment of acquired idiopathic generalized anhidrosis in Japan.
abstract: Acquired idiopathic generalized anhidrosis (AIGA) is characterized by an acquired impairment in total body sweating despite exposure to heat or exercise. Severe cases may result in heatstroke. Most cases of AIGA have been reported in Asia, especially in Japan. However, there is limited information on the epidemiology of this condition, and no diagnostic criteria or appropriate treatment options have been established. This guideline was developed to fill this gap. It contains information on the etiology, diagnosis, evaluation of disease severity and evidence-based recommendations for the treatment of AIGA. Appropriate treatment according to disease severity may relieve the clinical manifestations and emotional distress experienced by patients with AIGA.
authors: Department of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan.|Department of Dermatology, National Defense Medical College, Saitama, Japan.
authors: Takichi
authors: T
authors: Munetsugu
authors: Department of Dermatology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan.
authors: Tomoko
authors: T
authors: Fujimoto
authors: Department of Dermatology, Aichi Medical University, Aichi, Japan.
authors: Yuichiro
authors: Y
authors: Oshima
authors: Department of Clinical Laboratory Investigation, Shinshu University, Nagano, Japan.
authors: Kenji
authors: K
authors: Sano
authors: Department of Dermatology, School of Medicine, Osaka University, Suita, Japan.
authors: Hiroyuki
authors: H
authors: Murota
authors: Department of Dermatology, National Defense Medical College, Saitama, Japan.
authors: Takahiro
authors: T
authors: Satoh
authors: Department of Physiology, Aichi Medical University, Aichi, Japan.
authors: Satoshi
authors: S
authors: Iwase
authors: Department of Neurology, Chiba University, Chiba, Japan.
authors: Masato
authors: M
authors: Asahina
authors: Department of Neurology, Saitama Medical University, Saitama, Japan.
authors: Yoshihiko
authors: Y
authors: Nakazato
authors: Department of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan.
authors: Hiroo
authors: H
authors: Yokozeki
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D001706:Biopsy; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006633:Histamine Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007007:Hypohidrosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology; D007073:Immunoglobulin E / Q000097:blood; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D007564:Japan / Q000453:epidemiology; D011788:Quality of Life; D012955:Societies, Medical; D013817:Thermography
chemical_list: D004365:Drugs, Chinese Herbal; D005938:Glucocorticoids; D006633:Histamine Antagonists; D007166:Immunosuppressive Agents; C080903:sairei-to; D007073:Immunoglobulin E
keywords: acquired idiopathic generalized anhidrosis; anhidrosis; disease severity; guideline; hypohidrosis