title: One-Pot Synthesis and Transmembrane Chloride Transport Properties of C3-Symmetric Benzoxazine Urea.
abstract: One-pot synthesis of a C3-symmetric benzoxazine-based tris-urea compound is discussed.1H NMR titrations indicate a stronger Cl-binding compared that of Br-and I-by the receptor. Effective Cl-transport across liposomal membranes via a Cl-/X-antiport mechanism is confirmed. Theoretical calculation suggests that a few water molecules with N-H, C═O, and the aromatic ring of the receptor create a H-bonded polar cavity where a Cl-is recognized by O-H···Cl-interactions from five bridged water molecules.
authors: Department of Chemistry, Indian Institute of Science Education and Research Pune , Dr. Homi Bhabha Road, Pashan, Pune, 411008 Maharashtra, India.
authors: Arundhati
authors: A
authors: Roy
authors: Department of Chemistry, Indian Institute of Science Education and Research Pune , Dr. Homi Bhabha Road, Pashan, Pune, 411008 Maharashtra, India.
authors: Debasis
authors: D
authors: Saha
authors: Department of Chemistry, Indian Institute of Science Education and Research Pune , Dr. Homi Bhabha Road, Pashan, Pune, 411008 Maharashtra, India.
authors: Arnab
authors: A
authors: Mukherjee
authors: Department of Chemistry, Indian Institute of Science Education and Research Pune , Dr. Homi Bhabha Road, Pashan, Pune, 411008 Maharashtra, India.
authors: Pinaki
authors: P
authors: Talukdar