title: Bronchial schwannoma: a singular lesion as a cause of obstructive pneumonia.
abstract: Bronchial schwannomas are very rare pulmonary lesions, but its awareness is important to reach correct diagnosis and decide proper intervention. Clinical and radiological characteristics are mainly unspecific and pathological examination usually provides the definite diagnosis. In small lesions, endoscopic approach may be sufficient, but in large lesions associated with organising pneumonia surgical intervention may be required. Prognosis is typically favourable. We describe a case of a woman, aged 66 years, with productive cough and sporadic haemoptysis, dyspnoea, anorexia, excessive sweating and weight loss with 2 months evolution. CT scan showed a soft tissue dense lesion on the left hilum with 3.75 cm with 18-Fludeoxyglucose uptake. Left upper lobectomy was performed. Gross examination revealed a polypoid mass without necrosis, histologically showing cellular dense (Antoni A) and less dense (Antoni B) areas with Verocay bodies, slightly pleomorphic spindle cells, without mitotic activity and positive for S100 protein on immunohistochemistry.
authors: Department of Pathology, Hospitais da Universidade de Coimbra, Coimbra, Portugal.
authors: Rui Caetano
authors: RC
authors: Oliveira
authors: Hospitais da Universidade de Coimbra Centro de Cirurgia Cardiotoracica, Coimbra, Portugal.
authors: Tiago
authors: T
authors: Nogueira
authors: Coimbra's Medical College, Coimbra, Portugal.|Coimbra's Hospital and Universitary Center, Coimbra, Portugal.
authors: Vítor
authors: V
authors: Sousa
authors: Hospitais da Universidade de Coimbra, Coimbra, Portugal.
authors: Lina
authors: L
authors: Carvalho
mesh_terms: D000368:Aged; D000402:Airway Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D001984:Bronchial Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D064847:Multimodal Imaging; D009442:Neurilemmoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D000072078:Positron Emission Tomography Computed Tomography; D014057:Tomography, X-Ray Computed