title: [Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Evaluating Diffuse Tumor Infiltration of Bone Marrow in Patients with Acute Leukemia].
abstract: OBJECTIVE
  To analyze the value of dynamic contrast-enhanced magnetic resonance imaging (CEMRI) for evaluating diffuse tumor infiltration of bone marrow in patients with acute leukemia (AL).
  
  
  METHODS
  From January 2010 to February 2016, 80 AL patients admitted in our hospital were chosen as AL patient group, 100 healthy people were chosen as control group, and all subjects were diagnosed with MRI and CEMRI. The Emax and Slope of ilium and vertebra lumbalis were compared between AI patient and control groups. The relation of Emax and Slope with protocells % was analyzed.
  
  
  RESULTS
  The Emax and Slope of AL patients were significantly higher than those of control group (P<0.05). After treatment, the Emax and Slope of CR/PR patients decreased significantly (P<0.05). Multiple regression analysis showed that the protocells %=-0.5632+0.0540 Emax+0.0056 Slope. The Emax and Slope of AL patients had significant correlation with Protocells %(P<0.05).
  
  
  CONCLUSIONS
  The results of CEMRI relate with pathological examination and treatment effect.
authors: Department of Radiology, The First Affiliated Hospital of Xiamen Univetsity, Xiamen 361000, Fujian Province, China.
authors: De-Hao
authors: DH
authors: Liu
authors: Department of Radiology, The First Affiliated Hospital of Xiamen Univetsity, Xiamen 361000, Fujian Province, China.
authors: Jing-Qun
authors: JQ
authors: Wang
authors: Department of Radiology, The First Affiliated Hospital of Xiamen Univetsity, Xiamen 361000, Fujian Province, China.
authors: Xiao-Qiang
authors: XQ
authors: Wu
authors: Department of Radiology, The First Affiliated Hospital of Xiamen Univetsity, Xiamen 361000, Fujian Province, China. E-mail: zhuangxiongjievip@163.com.
authors: Xiong-Jie
authors: XJ
authors: Zhuan
authors: Department of Hematology, The First Affiliated Hospital of Xiamen Univetsity, Xiamen 361000, Fujian Province, China.
authors: Yong
authors: Y
authors: Zhou
mesh_terms: D000208:Acute Disease; D000368:Aged; D001853:Bone Marrow; D003287:Contrast Media; D006801:Humans; D015470:Leukemia, Myeloid, Acute; D008279:Magnetic Resonance Imaging; D015999:Multivariate Analysis
chemical_list: D003287:Contrast Media