title: Clinical Features and Prognosis of Herpetic Anterior Uveitis.
abstract: OBJECTIVE
  To evaluate clinical features, complications, visual outcomes and treatment modalities in patients clinically diagnosed with herpetic anterior uveitis (AU).
  
  
  METHODS
  We retrospectively reviewed the medical records of 67 patients seen at the Umraniye Training and Research Hospital, Ophthalmology Clinic, Uveitis and Cornea Department from January 2009 to June 2013.
  
  
  RESULTS
  Thirty-seven patients (55.2%) were female and 30 (44.7%) patients were male. The average follow-up period was 12.9 ± 10.6 months (range: 1-45 months). The most common ocular findings were granulomatous keratic precipitates (KPs) (82.2%), corneal involvement (62.6%), iris atrophy (41.7%) and transient elevated intraocular pressure (IOP) (40.2%). Recurrences were observed in 46.2% of the eyes and the median recurrence rate was 1.0 during the follow-up period. Topical steroids and oral antiviral (acyclovir) therapy were applied to all patients during active episodes. Long-term oral acyclovir was used in 29.8% of the patients. Recurrence rates were significantly lower in patients who used oral acyclovir for more than 6 months, whereas complications rates and final visual acuity did not show any difference between groups. Final visual acuity was better than 20/40 in 61.1% of eyes, and visual impairment was due to corneal scarring or cataract formation.
  
  
  CONCLUSIONS
  Herpetic AU can present with or without corneal involvement. Granulomatous KPs, iris atrophy and elevated IOP are important clinical findings for the diagnosis of cases without corneal involvement. Long-term oral acyclovir treatment (more than 6 months) and is important to decrease recurrence rates and possible complications. Visual prognosis is favorable in cases without corneal scarring.
authors: Ümraniye Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.
authors: Esra
authors: E
authors: Kardeş
authors: Ümraniye Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.
authors: Kansu
authors: K
authors: Bozkurt
authors: Ümraniye Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.
authors: Betül İlkay
authors: Bİ
authors: Sezgin Akçay
authors: Ümraniye Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.
authors: Cihan
authors: C
authors: Ünlü
authors: Ümraniye Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.
authors: Tuğba
authors: T
authors: Aydoğan Gezginaslan
authors: Ümraniye Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey.
authors: Ahmet
authors: A
authors: Ergin
keywords: Elevated intraocular pressure; granulomatous keratic precipitates; herpetic anterior uveitis; iris atrophy; oral acyclovir