title: Post-treatment Surveillance for Stage I and II Non-small Cell Lung Cancer: Impact on Clinical Outcome.
abstract: Patients treated for early-stage non-small cell lung cancer (NSCLC) need post-treatment surveillance for detecting recurrence of disease. The aim of this study was to provide evidence for the appropriate follow-up.
  
  
  
  The overall survival (OS), 1- and 3-year survival and progression-free survival (PFS) were retrospectively compared between two imaging modality groups. One group received only chest radiographs (CR group) and one group received chest radiographs and at least one computed tomography scan (CT group).
  
  
  
  Patients in the CR group (n=50) had no inferior OS (hazard ratio (HR)=1.427, 95% confidence interval (CI)=0.755-2.695, p=0.273) and PFS (HR=1.156, 95% CI=0.645-2.069, p=0.627) compared to patients in the CT group (n=23). Both 1- and 3-year survival were equal in the two groups (HR=5.544, 95% CI=0.530-58.031, p=0.153 and HR=1.540, 95% CI=0.752-3.154, p=0.238, respectively).
  
  
  
  Follow-up with a chest radiography did not result in inferior clinical outcomes compared to follow-up with a CT scan.
authors: Department of Pulmonology, St. Antonius Hospital, Nieuwegein, the Netherlands.
authors: Renata
authors: R
authors: Karzijn
authors: Department of Pulmonology, St. Antonius Hospital, Nieuwegein, the Netherlands.
authors: Leonie
authors: L
authors: Alberts
authors: Department of Epidemiology and Statistics, St. Antonius Hospital, Nieuwegein, the Netherlands.
authors: Johannes C
authors: JC
authors: Kelder
authors: Department of Cardiothoracic Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands.
authors: Frederik N
authors: FN
authors: Hofman
authors: Department of Radiotherapy, University Medical Centre Utrecht, Utrecht, the Netherlands.
authors: Sherif Y
authors: SY
authors: El Sharouni
authors: Department of Pulmonology, St. Antonius Hospital, Nieuwegein, the Netherlands.
authors: Elisabeth A
authors: EA
authors: Kastelijn
authors: Department of Pulmonology, St. Antonius Hospital, Nieuwegein, the Netherlands f.schramel@antoniusziekenhuis.nl.
authors: Franz M N H
authors: FM
authors: Schramel
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: CT scan; Early-stage non-small cell lung cancer; chest radiography; overall survival; progression free survival; surveillance