title: Inorganic Nanoparticles for Image-Guided Therapy.
abstract: Recently, nanotechnology has provided significant advances in biomedical applications including diagnosis and therapy. In particular, nanoparticles have emerged as valuable outcomes of nanotechnology due to their unique physicochemical properties based on size, shape, and surface properties. Among them, a large amount of research has reported imaging and therapeutic applications using inorganic nanoparticles with special properties. Inorganic nanoparticles developed for imaging and therapy contain metal (Au), metal oxide (Fe3O4, WO3, WO2.9), semiconductor nanocrystal (quantum dots (QDs)), and lanthanide-doped upconversion nanoparticles (UCNPs). Based on their intrinsic properties, they can generate heat, reactive oxygen species (ROS), or energy transfer, so that they can be used for both imaging and therapy. In this review, we introduce biocompatible inorganic nanoparticles for image-guided thermal and photodynamic therapy, and discuss their promising results from in vitro and in vivo studies for biomedical applications.
authors: Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology , 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
authors: Hong Yeol
authors: HY
authors: Yoon
authors: Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology , 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.|School of Chemical Engineering, Sungkyunkwan University , 2066, Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
authors: Sangmin
authors: S
authors: Jeon
authors: Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology , 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.|School of Chemical Engineering, Sungkyunkwan University , 2066, Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
authors: Dong Gil
authors: DG
authors: You
authors: School of Chemical Engineering, Sungkyunkwan University , 2066, Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea.
authors: Jae Hyung
authors: JH
authors: Park
authors: Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology , 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.|KU-KIST Graduate School of Converging Science and Technology, Korea University , 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
authors: Ick Chan
authors: IC
authors: Kwon
authors: Department of Medical Lifescience, College of Medicine, The Catholic University of Korea , 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea.
authors: Heebeom
authors: H
authors: Koo
authors: Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology , 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
authors: Kwangmeyung
authors: K
authors: Kim
mesh_terms: D006801:Humans; D006979:Hyperthermia, Induced; D007287:Inorganic Chemicals / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D053758:Nanoparticles / Q000737:chemistry*; D045663:Quantum Dots
chemical_list: D007287:Inorganic Chemicals