title: Bio Fabrication of Silver Nanoparticle from Argemone mexicana for the Control of Aedes albopictus and their Antimicrobial Activity.
abstract: BACKGROUND
  Plant synthesized silver nanoparticles give rapid control on mosquito larvae of dengue vector, Aedes albopictus. AgNPs synthesized from the plant, Argemone mexicana for the control of larvae and these nanoparticles inhibit the growth of microbes are broad spectrum of nanoparticle activities.
  
  
  METHODS
  Nanoparticles were subjected to analysis by UV-vis spectrophotometry, Fourier transform infrared spectroscopy, scanning electron microscopy and transmission electron microscopy. Furthermore, laboratory evaluation of plant mediated nano-particle carried out lethal toxicity on Aedes albopictus. The characterization studies confirmed the spherical shape and size (5-50 nm) of silver nano-particles.
  
  
  RESULTS
  The efficacy of AgNPs was tested at concentration of 2 to 10 ppm against L1 to L4 larval instar of A. albopictus. The LC50 followed by LC90 values were (L1) 5.24, 8.66; (L2) 5.56, 8.85; (L3) 6.20, 10.01 and (L4) 7.04, 10.92 at 10 ppm of silver nanoparticle, whereas LC50 (LC90) values of (L1) 7.63, 11.58; (L2) 8.17, 11.88; 8.80, 12.82 and 8.94, 12.26 at 10 ppm of plant extract alone treated larvae, respectively. The mortality rates were positively correlated with the concentration of AgNPs. Significant (P<0.05) high square value changes in the larval mortality were also recorded between the period of exposure against all larval instar of A. albopictus. Silver nanoparticles were also tested for antimicrobial activity and significant toxicity inhibition was observed against the gram positive microbes and it exhibited mild toxicity against P. aeroginosa.
  
  
  CONCLUSIONS
  Plant, A. mexicana synthesized silver nano-particles are rapid and potential mosquito larvicidal as well as antimicrobial agents. Finding of our results support that silver nanoparticles can be prepared in a simple and cost-effective manner and are suitable for bio-formulation against mosquitoes and microbes.
authors: Division of Medical Entomology, Department of Zoology, Bharathiar University, Coimbatore-641 046, Tamil Nadu, India. kamal410@yahoo.com.
authors: Siva
authors: S
authors: Kamalakannan
authors: Sivapunyam
authors: S
authors: Ananth
authors: Kadarkarai
authors: K
authors: Murugan
authors: Kalimuthu
authors: K
authors: Kovendan
authors: Marimuthu
authors: M
authors: Ramar
authors: Ponnan
authors: P
authors: Arumugam
authors: Balamurugan
authors: B
authors: Chandramohan
authors: Vellingiri
authors: V
authors: Balachandar
mesh_terms: D000330:Aedes; D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D031674:Argemone / Q000737:chemistry*; D004285:Dogs; D007814:Larva / Q000187:drug effects; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry; D012834:Silver / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D012834:Silver