title: Current best practice in the evaluation and management of malignant pleural effusions.
abstract: Malignant pleural effusions (MPEs) are an important cause of cancer-related mortality and morbidity. It is a heterogeneous group of conditions, which leads to debilitating symptoms and confers a poor prognosis. Recent well-designed randomized trials have provided a broader evidence base for an expanding range of treatment options. Together, with new prognostic scoring systems and a greater understanding of how different patient phenotypes respond to treatment, this allows greater personalization of management. This article will discuss the current evidence on evaluation and management of MPEs.
authors: Academic Respiratory Unit, University of Bristol, Bristol, UK.
authors: Steven
authors: S
authors: Walker
authors: Academic Respiratory Unit, University of Bristol, Bristol, UK.
authors: Anna C
authors: AC
authors: Bibby
authors: Academic Respiratory Unit, University of Bristol, Southmead Road, Bristol BS10 5NB, UK.
authors: Nick A
authors: NA
authors: Maskell
mesh_terms: D006801:Humans; D010641:Phenotype; D016066:Pleural Effusion, Malignant / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D057285:Precision Medicine / Q000379:methods*; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D012107:Research Design
keywords: indwelling pleural catheter; malignant; mesothelioma; pleural disease; pleural effusion; pleurodesis