title: Retinal pigment epithelium wound healing after traumatic choroidal rupture.
abstract: OBJECTIVE
  The aim of this study was to investigate wound healing in the retinal pigment epithelium (RPE) after traumatic indirect choroidal rupture using fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (SD-OCT).
  
  
  METHODS
  A total of 14 eyes of 14 patients with traumatic indirect choroidal rupture were included. Baseline and last follow-up FAF images were compared to evaluate the extent of RPE healing after choroidal rupture, and associated morphologic characteristics were examined by SD-OCT.
  
  
  RESULTS
  The size of the RPE lesion was reduced in five eyes. The change occurred in the fovea in four eyes and in the macula in three eyes. The change was noted in both the fovea and the macula in two eyes; in these cases, the changes were more prominent in the fovea than in the macula. Extra-macular lesions and lesions with deep choroidal involvement did not show any reduction in size. Choroidal neovascularization (CNV) developed in seven eyes. There was no extra-macular CNV.
  
  
  CONCLUSIONS
  Retinal pigment epithelium (RPE) wound healing after traumatic choroidal rupture is affected by location and extent of the lesion.
authors: Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea.|Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.
authors: Joo Youn
authors: JY
authors: Shin
authors: Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.
authors: Byunghoon
authors: B
authors: Chung
authors: Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea.
authors: Yun Hyup
authors: YH
authors: Na
authors: Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea.
authors: Jonghyun
authors: J
authors: Lee
authors: Department of Ophthalmology, Konkuk University School of Medicine, Seoul, South Korea.
authors: Hyewon
authors: H
authors: Chung
authors: Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.
authors: Suk Ho
authors: SH
authors: Byeon
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002829:Choroid / Q000293:injuries*; D020256:Choroidal Neovascularization / Q000209:etiology / Q000473:pathology; D005131:Eye Injuries / Q000150:complications / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D055213:Retinal Pigment Epithelium / Q000293:injuries / Q000473:pathology*; D012189:Retrospective Studies; D012421:Rupture; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods*; D014945:Wound Healing; D055815:Young Adult
keywords: choroidal rupture; fundus autofluorescence; optical coherence tomography; retinal pigment epithelium; wound healing