title: Case of Pediatric Bullous Systemic Lupus Erythematosus Treated with Intravenous Immunoglobulin.
abstract: This is a case report of a 16-year-old girl recently diagnosed with systemic lupus erythematosus (SLE) who presented with multiple blisters on the face, hands, arms, legs, trunk, and vaginal and oral mucosa. Skin biopsy was consistent with bullous SLE (BSLE). Dapsone is often the first-line treatment option for BSLE, but the patient's history of anemia and leukopenia and long-term immunosuppression requirement for her systemic symptoms raised concerns about dapsone and bone marrow toxicity, especially hemolytic anemia and agranulocytosis. She was started on intravenous immunoglobulin (IVIG), 2 g/kg divided over 3 days, with significant improvement in her cutaneous symptoms. IVIG is a treatment option for BSLE patients in whom agents such as dapsone are contraindicated.
authors: Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Margit
authors: M
authors: Juhász
authors: Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Megan
authors: M
authors: Rogge
authors: Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Mary
authors: M
authors: Chen
authors: Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Annette
authors: A
authors: Czernik
authors: Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Soo
authors: S
authors: Jung Kim
authors: Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.|Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Lauren
authors: L
authors: Geller
mesh_terms: D000293:Adolescent; D003622:Dapsone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008178:Lupus Erythematosus, Cutaneous / Q000473:pathology / Q000628:therapy*; D012867:Skin / Q000473:pathology*
chemical_list: D016756:Immunoglobulins, Intravenous; D003622:Dapsone