title: Effect of Combination of Non-Invasive Spinal Cord Electrical Stimulation and Serotonin Receptor Activation in Patients with Chronic Spinal Cord Lesion.
abstract: We analyzed the efficiency of percutaneous electrical stimulation of the spinal cord and serotonin receptor activation in rehabilitation of paralyzed patients. Four-week course of spinal cord electrical stimulation combined with mechanotherapy produced positive shifts in the status of chronically paralyzed patients. Serotonin receptor activation potentiated the effect of spinal cord stimulation and can be regarded as an additional neurorehabilitation option.
authors: I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, Moscow, Russia. tmoshonkina@gmail.com.
authors: T R
authors: TR
authors: Moshonkina
authors: St. Petersburg Research Institute of Phthisiopulmonology, the Ministry of Health, St. Petersburg, Russia.
authors: E Yu
authors: EY
authors: Shapkova
authors: I. P. Pavlov First St. Petersburg State Medical University, Ministry of Health, St. Petersburg, Russia.
authors: I A
authors: IA
authors: Sukhotina
authors: St. Petersburg Research Institute of Phthisiopulmonology, the Ministry of Health, St. Petersburg, Russia.
authors: D V
authors: DV
authors: Emeljannikov
authors: I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, Moscow, Russia.
authors: Yu P
authors: YP
authors: Gerasimenko
mesh_terms: D000328:Adult; D000368:Aged; D002065:Buspirone / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D059225:Nociception / Q000187:drug effects / Q000502:physiology; D011985:Receptors, Serotonin / Q000378:metabolism*; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use*; D013116:Spinal Cord / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D013119:Spinal Cord Injuries / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D062187:Spinal Cord Stimulation / Q000379:methods*; D055698:Touch Perception / Q000187:drug effects / Q000502:physiology; D016896:Treatment Outcome
chemical_list: D011985:Receptors, Serotonin; D017366:Serotonin Receptor Agonists; D002065:Buspirone
keywords: buspirone; complete and incomplete plegia; electric stimulation of the spinal cord; neurological performance