title: Quality of life after paediatric ischaemic stroke.
abstract: Paediatric arterial ischaemic stroke can lead to reduced quality of life (QoL). It is important to identify predictors of QoL to support recovery. We examined long-term QoL after arterial ischaemic stroke concerning different variables.
  
  
  
  Children registered in the Swiss Neuropediatric Stroke Registry and suffering from arterial ischaemic stroke between 2000 and 2008 were included. Two years post-stroke, assessments included intelligence quotient tests for cognitive impairment and modified Rankin Scale (mRS) for neurological impairment; 5 years post-stroke, the Kidscreen-27 was used for QoL, DSM-IV criteria screening was used for attention deficits, and the ABILHAND-Kids was used for manual motor skills. Age at stroke, sex, socioeconomic status, lesion characteristics, neuropsychological and motor outcome, and mRS were correlated with QoL measures.
  
  
  
  Seventy children were examined (49 males, 21 females; mean age 7y 2wks). Age at stroke, sex, socioeconomic status, and lesion characteristics did not influence QoL; IQ below average and attention deficits partially influenced QoL. The highest predictive value for QoL was found for manual motor impairment (p=0.002) and mRS scores (p=0.013). Combined motor, cognitive, and attention impairment negatively affected QoL (p=0.001).
  
  
  
  Neurological and cognitive impairments after paediatric arterial ischaemic stroke negatively influence QoL. Children with motor and neurological problems, as well as those with combined motor, cognitive, and attention problems, are at higher risk for low QoL.
authors: University Children's Hospital Bern, Bern, Switzerland.|Center for Cognition, Learning and Memory, University of Bern, Bern, Switzerland.
authors: Salome
authors: S
authors: Kornfeld
authors: University Children's Hospital Bern, Bern, Switzerland.|Center for Cognition, Learning and Memory, University of Bern, Bern, Switzerland.
authors: Martina
authors: M
authors: Studer
authors: University Children's Hospital Bern, Bern, Switzerland.
authors: Stephanie
authors: S
authors: Winkelbeiner
authors: University Children's Hospital Bern, Bern, Switzerland.
authors: Mária
authors: M
authors: Regényi
authors: University Children's Hospital Zürich, Zürich, Switzerland.
authors: Eugen
authors: E
authors: Boltshauser
authors: University Children's Hospital Bern, Bern, Switzerland.|Center for Cognition, Learning and Memory, University of Bern, Bern, Switzerland.
authors: Maja
authors: M
authors: Steinlin
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000704:Analysis of Variance; D002545:Brain Ischemia / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D007360:Intelligence; D008297:Male; D009460:Neurologic Examination; D010290:Parents / Q000523:psychology; D011788:Quality of Life / Q000523:psychology*; D012189:Retrospective Studies; D057566:Self Report; D012737:Sex Factors; D020521:Stroke / Q000209:etiology* / Q000523:psychology*