title: Retinal oxygen saturation before and after glaucoma surgery.
abstract: OBJECTIVE
  This study compared retinal vessel oxygen saturation before and after glaucoma surgery.
  
  
  METHODS
  Retinal oxygen saturation in glaucoma patients was measured using a non-invasive spectrophotometric retinal oximeter. Adequate image quality was found in 49 of the 108 consecutive glaucoma patients recruited, with 30 undergoing trabeculectomy, 11 EX-PRESS and eight trabeculotomy. Retinal oxygen saturation measurements in the retinal arterioles and venules were performed at 1 day prior to and at approximately 10 days after surgery. Statistical analysis was performed using a Student's t-test.
  
  
  RESULTS
  After glaucoma surgery, intraocular pressure (IOP) decreased from 19.8 ± 7.7 mmHg to 9.0 ± 5.7 mmHg (p < 0.001). Although oxygen saturation in retinal arterioles remained unchanged before and after surgery (104.7 ± 10.6% before and 105.4 ± 9.3% after surgery, p = 0.58), the oxygen saturation in the venules increased from 54.9 ± 7.4% to 57.4 ± 5.7% (p = 0.01).
  
  
  CONCLUSIONS
  Intraocular pressure (IOP) decreases caused by glaucoma surgery had an effect on the retinal venous oxygen saturation.
authors: Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.
authors: Eri
authors: E
authors: Nitta
authors: Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.
authors: Kazuyuki
authors: K
authors: Hirooka
authors: Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.
authors: Takeru
authors: T
authors: Shimazaki
authors: Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.
authors: Shino
authors: S
authors: Sato
authors: Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.
authors: Kaori
authors: K
authors: Ukegawa
authors: Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.
authors: Yuki
authors: Y
authors: Nakano
authors: Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.
authors: Akitaka
authors: A
authors: Tsujikawa
mesh_terms: D005260:Female; D005901:Glaucoma / Q000175:diagnosis / Q000378:metabolism* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry / Q000379:methods; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption; D011184:Postoperative Period; D057234:Preoperative Period; D012160:Retina / Q000378:metabolism*; D014130:Trabeculectomy; D014794:Visual Fields
chemical_list: D010100:Oxygen
keywords: glaucoma surgery; intraocular pressure; oxygen saturation; retinal oximetry