title: [Analysis of screening for colorectal cancer high-risk groups in Harbin, China 2012-2015].
abstract: OBJECTIVE
  To evaluate the result of colorectal cancer screening for high-risk groups in Harbin, China from 2012 to 2015.
  
  
  METHODS
  According to the Project of National Colorectal Cancer Screening in Urban Area, epidemiological investigation and cancer risk evaluation established by National Cancer Center were performed among 40-69 years old residents in Harbin. Questionnaires were issued to assess high-risk groups for clinical screening, including colonoscope examination. The results of colorectal screening were evaluated in detail.
  
  
  RESULTS
  Project of Colorectal Cancer Screening in Urban Area was completed successfully from 2012 to 2015 in various districts of Harbin. The accomplishment of high-risk assessment included 3 017 people, while 2 996 people received the clinical screening, including 1 376 males and 1 629 females, from 40 to 69 (53.3±7.1) years old. Among 2 996 people, 1 158 cases of colorectal polyps(38.7%) were screened, including 36.6%(901/2 465) cases of age<60 and 48.4%(257/531) cases of age>60 years old with significant difference (χ2=19.19, P<0.01), and 47.6% (651/1 367) cases of male and 31.1%(507/1 629) cases of female with significant difference (χ2=85.33, P<0.01). Of 1 158 polyps patients, 141 received the pathological examination and 11 patients were diagnosed as colorectal cancer, accounting for 0.4% of overall screening people (11/2 996). All these 11 patients underwent operation by advice and the postoperative pathology results all indicated early adenocarcinoma. Furthermore, among 141 polyps patients, 97 cases of tubular adenoma were found, which were distributed as follows: 2 cases of cecum (2.1%), 14 cases of ascending colon(14.4%), 12 cases of transverse colon (12.4%), 15 cases of descending colon (15.5%), 35 cases of sigmoid colon (36.1%) and 19 cases of rectum(19.6%).
  
  
  CONCLUSIONS
  With the increase in age, the risk of colorectal polyps is significantly elevated. The males have higher incidence of colorectal polyps than the females. Adenoma mainly locates in the distal colon and rectum, especially in the sigmoid colon. Early screening for high-risk group can find out colorectal precancerosis and cancer, so the patients can receive early treatment.
authors: Dawei
authors: D
authors: Song
authors: Rui
authors: R
authors: Huang
authors: Tianyi
authors: T
authors: Ma
authors: Yinggang
authors: Y
authors: Chen
authors: Jiaying
authors: J
authors: Li
authors: Department of Colorectal Tumor Surgery, The Second Affiliated Hospital, Harbin Medical University, Harbin 150086, China. wxshan1208@126.com.
authors: Xishan
authors: X
authors: Wang
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D000236:Adenoma / Q000175:diagnosis*; D000368:Aged; D002432:Cecum; D002681:China; D044682:Colon, Ascending; D012809:Colon, Sigmoid; D044684:Colon, Transverse; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D015994:Incidence; D007417:Intestinal Polyps; D008297:Male; D008875:Middle Aged; D012007:Rectum; D012306:Risk; D011795:Surveys and Questionnaires