title: Central or Peripheral Precocious Puberty: Diagnostic Difficulties.
abstract: BACKGROUND
  An underlying identifiable organic cause is present in up to 50% cases of central precocious puberty in male patients.
  
  
  METHODS
  A 7-years-8-months-old presented with delayed puberal development. Analytical examinations showed suppressed basal and stimulated levels of testosterone, LH and FSH. Abdominal ultrasound and contrast cranial magnetic resonance results were initially negative.
  
  
  RESULTS
  Germinoma was found on cranial computer tomography.
  
  
  CONCLUSIONS
  There is often a wide time-lapse between symptoms and diagnosis of germinoma, so frequent monitoring is vital.
authors: Departments of *Endocrinology and Nutrition, and #Pediatric Endocrinology; Hospital Universitario Miguel Servet, Spain. Correspondence to: Dr María Eugenia López Valverde. Endocrinology and Nutrition, Hospital Universitario Miguel Servet, Spain. eukane_lpz@hotmail.com.
authors: María Eugenia López
authors: ME
authors: Valverde
authors: Ana Villamañán
authors: AV
authors: Montero
authors: Aránzazu Garza
authors: AG
authors: Espí
authors: Antonio de Arriba
authors: AA
authors: Muñoz
mesh_terms: D002648:Child; D005640:Follicle Stimulating Hormone / Q000097:blood; D018237:Germinoma / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010871:Pinealoma / Q000150:complications / Q000000981:diagnostic imaging; D011629:Puberty, Precocious; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone