title: Transarterial Chemoembolization Monotherapy in Combination with Radiofrequency Ablation or Percutaneous Ethanol Injection for Hepatocellular Carcinoma.
abstract: OBJECTIVE
  To evaluate whether combined transarterial chemoembolization (TACE) with radiofrequency ablation (RFA) or percutaneous ethanol injection (PEI) for hepatocellular carcinoma (HCC) have superior efficacy to transarterial chemoembolization (TACE) alone a retrospective review was conducted.
  
  
  METHODS
  During January 2009 to March 2013, 108 patients with hepatocellular carcinoma underwent TACE or combined therapies (TACE+RFA or TACE+PEI). The long-term survival rates were evaluated in those patients by various statistical analyses.
  
  
  RESULTS
  The cumulative survival rates in the combined TACE+RFA/PEI group were significantly superior to those in the TACE alone group. When the comparison among the groups was restricted to patients with two or three tumors fulfilling the Milan criteria, significantly greater prolongation of survival was observed in the combined TACE+ RFA/PEI group than in the RFA/PEI alone group.
  
  
  CONCLUSIONS
  In terms of the effect on the survival period, combined TACE+ RFA/PEI therapy was more effective than TACE monotherapy, and also more effective than PEI or RFA monotherapy in cases with multiple tumors.
authors: Department of Interventional Radiology, Subei Peopleandapos;s Hospital of Jiangsu Province, Clinical Hospital of Yangzhou University, Yangzhou, China E-mail : huangxinen06@163.com, whycn77sina.com.
authors: Chuan
authors: C
authors: Xu
authors: Peng-Hua
authors: PH
authors: Lv
authors: Xin-En
authors: XE
authors: Huang
authors: Shu-Xiang
authors: SX
authors: Wang
authors: Ling
authors: L
authors: Sun
authors: Fu-An
authors: FA
authors: Wang
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000601:surgery* / Q000628:therapy*; D017115:Catheter Ablation / Q000379:methods; D016461:Chemoembolization, Therapeutic / Q000379:methods; D003131:Combined Modality Therapy / Q000379:methods; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery* / Q000628:therapy*; D008297:Male; D012189:Retrospective Studies; D015996:Survival Rate
chemical_list: D000431:Ethanol