title: [Effect of impaired tissue function on pharmacokinetics of anti-osteoporotic drugs.]
abstract: It is necessary to achieve pharmacotherapy appropriate to individual patient with respect to effectiveness and safety. Since drugs are given to patients with various kinds of diseases and conditions, in which pharmacokinetics greatly changes, we need to understand the relationship between pharmacokinetics and patient's condition, minimizing the individual differences in drug efficacy and toxicity. In this report, I outline the alteration of pharmacokinetics of anti-osteoporotic drugs in patients with various diseases and conditions.
authors: Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Hokuriku University, Japan.
authors: Tatsuo
authors: T
authors: Takahashi
mesh_terms: D050071:Bone Density Conservation Agents / Q000493:pharmacokinetics*; D006801:Humans; D007677:Kidney Function Tests; D008107:Liver Diseases / Q000150:complications; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy*
chemical_list: D050071:Bone Density Conservation Agents