title: Metal-Free and Versatile Synthetic Routes to Natural and Synthetic Prodiginines from Boron Dipyrrin.
abstract: Prodiginines, as a family of bacterial alkaloids, possess a number of interesting biological activities. New, concise synthetic routes for the facile preparation of both synthetic and natural prodiginines in good yields have been developed, which use BODIPY functionalization reactions, such as condensation, nucleophilic substitution, and BF2deprotection. This new metal-free synthetic method opens the door toward a wide variety of C-ring functionalized prodiginines, including those that are not possible to obtain through current synthetic methods, for their advanced biological activities.
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Jin
authors: J
authors: Li
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Qian
authors: Q
authors: Zhang
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Jian
authors: J
authors: Yin
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Changjiang
authors: C
authors: Yu
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Kai
authors: K
authors: Cheng
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Yun
authors: Y
authors: Wei
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Erhong
authors: E
authors: Hao
authors: Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University , Wuhu 241000, China.
authors: Lijuan
authors: L
authors: Jiao