title: Embryonic ring closure: Actomyosin rings do the two-step.
abstract: Actomyosin rings drive numerous closure processes, but the mechanisms by which they contract are still poorly understood. In this issue, Xue and Sokac (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201608025) show that actomyosin ring closure during Drosophila melanogaster cellularization uses two steps, only one of which involves Myosin-2.
authors: Massachusetts Institute of Technology, Cambridge, MA 02139 acmartin@mit.edu.
authors: Adam C
authors: AC
authors: Martin
mesh_terms: D000199:Actins / Q000378:metabolism; D000205:Actomyosin / Q000378:metabolism*; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D029721:Drosophila Proteins / Q000378:metabolism; D004331:Drosophila melanogaster / Q000196:embryology* / Q000378:metabolism*; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D008954:Models, Biological; D009218:Myosins / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D000199:Actins; D029721:Drosophila Proteins; D000205:Actomyosin; D009218:Myosins