title: Total synthesis of (±)-ganocins B and C.
abstract: The first total synthesis of structurally unique polycyclic phenolic meroterpenoids, ganocins B and C is reported. The synthesis features gold-catalyzed intramolecular cascade cyclization to construct the C/D ring bearing an angular methyl group, diastereoselective Michael addition, and acid-mediated one-pot Robinson cyclization/deprotection/isomerization.
authors: School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
authors: Yao
authors: Y
authors: Liu
authors: School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
authors: Chu-Jun
authors: CJ
authors: Zhou
authors: School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100191, China. liqingj3@mail.sysu.edu.cn wanghg3@mail.sysu.edu.cn.
authors: Qingjiang
authors: Q
authors: Li
authors: School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
authors: Honggen
authors: H
authors: Wang
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D003500:Cyclization; D013237:Stereoisomerism; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D013729:Terpenes