title: The Need and Potential of Inactivated Poliovirus Vaccine.
abstract: As the polio endgame progresses, the world will increasingly rely on inactivated polio vaccine (IPV) for protection against polio (wild and vaccine-related) and for risk mitigation during the phased removal of oral polio vaccine (OPV). IPV has already been introduced in most countries and strategies are underway to ensure the remaining OPV-only using countries succeed in introducing IPV in light of operational challenges. Questions remain as to the ideal dosing schedule for IPV in developing countries as well as the length of time for IPV to be administered beyond certification of eradication of wild polioviruses and total OPV withdrawal. IPV policies will likely evolve and new technologies will become available to meet unforeseen needs during this historical and unprecedented public health endeavor. Pediatricians in India have a crucial role to play in this global effort by supporting the overall polio eradication strategy and ensuring that all targeted children in India receive IPV.
authors: Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA, and Retired Professor of Clinical Virology, Christian Medical College, Vellore, Tamil Nadu, India. Correspondence to: Julie Garon, Emory University, School of Medicine, Division of Infectious Diseases, 1462 Clifton Road, Room 446, Atlanta, GA 30322, USA. julie.garon@emory.edu.
authors: Julie
authors: J
authors: Garon
authors: Walter
authors: W
authors: Orenstein
authors: T Jacob
authors: TJ
authors: John
mesh_terms: D002648:Child; D003906:Developing Countries; D060740:Disease Eradication / Q000379:methods*; D014943:Global Health; D006801:Humans; D011051:Poliomyelitis / Q000517:prevention & control / Q000821:virology; D011054:Poliovirus Vaccine, Inactivated; D011055:Poliovirus Vaccine, Oral / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D011054:Poliovirus Vaccine, Inactivated; D011055:Poliovirus Vaccine, Oral