title: Peritoneal dialysis for the management of pediatric patients with acute kidney injury.
abstract: Renal replacement therapy (RRT) is the most important supportive measure used in the management of acute kidney injury (AKI). Peritoneal dialysis (PD) is a safe, simple and inexpensive procedure and has been used in pediatric AKI patients, ranging from neonates to adolescents. It is the modality of choice for RRT in developing countries with cost constraints and limited resources. However, its use has declined with the availability of newer types of extracorporeal modalities for RRT in the developed world. Much controversy exists regarding the dosing and adequacy of PD in the management of AKI. Data in infants and children have shown that PD can provide adequate clearance, ultrafiltration and correction of metabolic abnormalities even in those who are critically ill. Although there are no prospective studies in children, data from retrospective studies reveal no differences in mortality rates between different modalities of RRT. In this review, we discuss the advantages and limitations of PD, indications for acute PD, strategies to improve the efficiency of acute PD and outcomes of PD in children with AKI.
authors: Department of Pediatric Nephrology, St. John's Medical College Hospital, Bengaluru, Karnataka, India, 560034. anil.vasudevan@sjri.res.in.
authors: Anil
authors: A
authors: Vasudevan
authors: Rainbow Children's Hospital, Bengaluru, India.
authors: Kishore
authors: K
authors: Phadke
authors: Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.|Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore, Singapore.
authors: Hui-Kim
authors: HK
authors: Yap
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D057785:Catheters; D002648:Child; D016638:Critical Illness; D003906:Developing Countries; D006330:Heart Defects, Congenital / Q000601:surgery; D017583:Hemodiafiltration / Q000009:adverse effects / Q000191:economics / Q000379:methods* / Q000639:trends; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010530:Peritoneal Dialysis / Q000009:adverse effects / Q000191:economics / Q000379:methods* / Q000639:trends; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000628:therapy; D018805:Sepsis / Q000150:complications; D061665:Time-to-Treatment; D016896:Treatment Outcome
keywords: Acute kidney injury; Peritoneal dialysis; Prescription; Renal replacement therapy