title: Giant Adrenal Cavernous Hemangioma in a Patient with Familial Adenomatous Polyposis.
abstract: Adrenal hemangioma is an uncommon benign vascular tumor that is often discovered incidentally. It has never been reported in association with familial adenomatous polyposis. We report a case of a 60-year old man with a history of familial adenomatous polyposis, in whom a huge retroperitoneal cyst of 18x17 cm was discovered during routine radiologic evaluation. Because of the impossibility of ruling out the presence of malignancy, surgical cystectomy was performed, associated to a scheduled total colectomy. Pathological examination revealed that the cyst corresponded to an adrenal cavernous hemangioma. Colonic adenomas did not show signs of degeneration. Screening for adenomatous polyposis coli(APC)gene mutation was not carried out. As familial adenomatous polyposis is known to involve a variety of extracolonic manifestations, this finding raises the suspicion of a possible variant of this syndrome including adrenal hemangioma. An extensive study based on a larger patient series with genetic exploration is necessary.
authors: Pathology Department, Med Tahar Maamouri Hospital, Tunis El Manar University , Tunis, Tunisia.
authors: Dhouha
authors: D
authors: Bacha
authors: Pathology Department, Med Tahar Maamouri Hospital, Tunis El Manar University , Tunis, Tunisia.
authors: Abir
authors: A
authors: Chaabane
authors: Pathology Department, Med Tahar Maamouri Hospital, Tunis El Manar University , Tunis, Tunisia.
authors: Fatma
authors: F
authors: Khanche
authors: Pathology Department, Med Tahar Maamouri Hospital, Tunis El Manar University , Tunis, Tunisia.
authors: Saloua
authors: S
authors: Néchi
authors: Surgery Department, Med Tahar Maamouri Hospital, Tunis El Manar University , Tunis, Tunisia.
authors: Hassen
authors: H
authors: Touinsi
authors: Pathology Department, Med Tahar Maamouri Hospital, Tunis El Manar University , Tunis, Tunisia.
authors: Emna
authors: E
authors: Chelbi
keywords: Hemangioma; adrenal gland; cavernous; familial adenomatous polyposis