title: Ultrasound-guided transcervical radiofrequency ablation for symptomatic uterine adenomyosis.
abstract: OBJECTIVE
  To retrospectively evaluate the midterm outcomes of transvaginal ultrasound-guided radiofrequency ablation (RFA) for the treatment of symptomatic uterine adenomyosis.
  
  
  METHODS
  87 patients with symptomatic uterine adenomyosis, who met the inclusion criteria, were enrolled in our study from January 2013 to October 2015. All of the patients underwent transvaginal ultrasound-guided RFA and were followed up for 12 months. Assessment end points included uterus volume reduction rate, lesion regression rate, dysmenorrhoeal score, symptom severity score (SSS) and adverse events.
  
  
  RESULTS
  In all 87 patients, 81 patients fulfilled the follow-up evaluations post-ablation. The mean uterine volume reduction rate was 35.8% at 1 month, 40.8% at 6 months and 41.2% at 12 months post-ablation. Dysmenorrhoea and SSS statistically significantly declined. Reintervention rate was 18.5%. Two patients developed intrauterine adhesion after ablation. No serious complications including penetration or burn injuries of the nearby organs were observed.
  
  
  CONCLUSIONS
  Ultrasound-guided RFA might be a safe and effective minimally invasive alternative in the treatment of symptomatic adenomyosis. Advances in knowledge: This is the first study to evaluate the efficacy and safety of ultrasound-guided RFA for the treatment of adenomyosis to our knowledge. This is also the first study to provide various changes of intrauterine cavity after this treatment.
authors: Department of Gynecology, PLA Rocket Force General Hospital, Beijing, China.
authors: Ning
authors: N
authors: Hai
authors: Department of Gynecology, PLA Rocket Force General Hospital, Beijing, China.
authors: Qingxiang
authors: Q
authors: Hou
authors: Department of Gynecology, PLA Rocket Force General Hospital, Beijing, China.
authors: Xiaoping
authors: X
authors: Ding
authors: Department of Gynecology, PLA Rocket Force General Hospital, Beijing, China.
authors: Xiangping
authors: X
authors: Dong
authors: Department of Gynecology, PLA Rocket Force General Hospital, Beijing, China.
authors: Meijuan
authors: M
authors: Jin
mesh_terms: D062788:Adenomyosis / Q000473:pathology / Q000601:surgery*; D000328:Adult; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods; D002681:China; D015331:Cohort Studies; D004412:Dysmenorrhea / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D057086:High-Intensity Focused Ultrasound Ablation / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology / Q000601:surgery*; D061214:Patient Safety; D018579:Patient Selection; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome