title: Sinus Augmentation by Platelet-Rich Fibrin Alone: A Report of Two Cases with Histological Examinations.
abstract: In sinus floor augmentation of an atrophic posterior maxilla, platelet-rich fibrin (PRF) has been used as a graft material. We herein report two cases with histological evaluations of PRF after the surgery. The first case was a 28-year-old female with an atrophic right posterior maxilla who was treated with sinus floor augmentation and simultaneous implant placement using PRF as the sole graft material in our hospital. Twenty-four months after surgery, the implant was unfortunately removed because of occlusal overloading by parafunctional habits. During implant replacement, a tissue sample was obtained from the site of augmentation with PRF and was evaluated histologically. The second case was a 58-year-old man with severe alveolar atrophy of the right maxilla who underwent lateral sinus augmentation using only PRF in a two-stage procedure in our hospital. Samples were obtained at the second-stage surgery and histological examinations were performed. As a result, new bone formation was confirmed histologically in both cases. Our findings show that the use of PRF as a graft material during sinus floor augmentation induces natural bone regeneration.
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Naofumi
authors: 0000-0003-4017-2360
authors: N
authors: Aoki
authors: Hakata Dental Clinic, Fukuoka 812-0011, Japan.
authors: Takeo
authors: T
authors: Kanayama
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Michinori
authors: M
authors: Maeda
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Koichiro
authors: K
authors: Horii
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Hironori
authors: H
authors: Miyamoto
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Keinoshin
authors: K
authors: Wada
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Yasutaka
authors: Y
authors: Ojima
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Tsukasa
authors: T
authors: Tsuchimochi
authors: Department of Oral Maxillofacial Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
authors: Yasuyuki
authors: Y
authors: Shibuya