title: Comparative effects of in ovo versus subcutaneous administration of the Marek's disease vaccine and pre-placement holding time on the post-hatch performance of Ross 708 broilers1,2,3.
abstract: Effects of 2 types of methods of administration (moa; in ovo or s.c.) of the Marek's disease (MD) vaccine and 4 and 18 h pre-placement holding times (pht) on the performance of male broilers through 48 d of age were investigated. Ross 708 broiler hatching eggs (3,900) were either in ovo-vaccinated at 18 d of incubation or chicks from eggs that were not in ovo-injected were vaccinated s.c. at hatch, and chicks from each moa group were held for one of the 2 pht. In ovo injections (50 μL) were delivered by a commercial multi-egg injector and s.c. injections (0.2 mL) were delivered by an automatic pneumatic s.c. injector. Sixteen birds were assigned to each of 15 replicate floor pens belonging to each of the 4 moa and pht combination groups. Mortality and BW gain were determined at weekly intervals, and feed consumption and conversion were determined in the zero to 14, 14 to 28, 28 to 42, and 42 to 48 d age intervals. No interactive effects between moa and pht were observed for any variable, and mortality was not significantly affected by moa or pht. The 14 to 28 d feed consumption and 14 to 21 d BW gain of s.c.-vaccinated birds were lower than that of in ovo-vaccinated birds, and the increase in pht from 4 to 18 h decreased feed consumption through 28 d post hatch and BW gain through 35 d post hatch. Overall, the performances of male Ross 708 broilers through 48 d of age in response to in ovo and s.c. injections of the MD vaccine were comparable, and delays in hatchling placement should be less that 18 h in duration. Furthermore, despite the decrease in BW gain through 35 d associated with the reduction in feed consumption through 28 d in response to the 14 h increase in pht, in ovo injection did not exacerbate the effect of the increase in pht.
authors: Department of Poultry Science, Mississippi State University, Mississippi State, MS 39762.
authors: E D
authors: ED
authors: Peebles
authors: Zoetis, 1040 Swabia Court, Research Triangle Park, NC 27709.
authors: T M
authors: TM
authors: Barbosa
authors: Zoetis, 1040 Swabia Court, Research Triangle Park, NC 27709.
authors: T S
authors: TS
authors: Cummings
authors: Zoetis, 1040 Swabia Court, Research Triangle Park, NC 27709.
authors: J
authors: J
authors: Dickson
authors: Department of Poultry Science, Mississippi State University, Mississippi State, MS 39762.
authors: S K
authors: SK
authors: Womack
authors: Department of Mathematical Sciences, Clemson University, Clemson, SC 29634.
authors: P D
authors: PD
authors: Gerard
mesh_terms: D000818:Animals; D002645:Chickens / Q000254:growth & development*; D007267:Injections / Q000662:veterinary; D007279:Injections, Subcutaneous / Q000662:veterinary; D008297:Male; D022501:Marek Disease Vaccines / Q000008:administration & dosage* / Q000009:adverse effects; D010063:Ovum; D015430:Weight Gain
chemical_list: D022501:Marek Disease Vaccines
keywords: broiler; holding time; in ovo injection; performance; vaccination