title: Role of PET-CT in the assessment of myocardial viability in patients with left ventricular dysfunction.
abstract: OBJECTIVE
  Role of PET-CT in assessment of myocardial viability in patients with LV dysfunction.
  
  
  METHODS
  This prospective study included 120 patients with LV dysfunction who underwent 99mTechnetium-Sestamibi myocardial perfusion SPECT-CT and 18FFDG cardiac PET-CT. They also underwent serial echocardiography and coronary angiography along with myocardial perfusion and FDG PET study.
  
  
  RESULTS
  Thirty-three patients had single vessel disease, 48 had triple vessel disease, and rest had double vessel disease. Among 786 segments, matched defects were seen in 432 (55%) and mismatched defects in 354 (45%) segments. 78 patients were surgically managed, and 42 were medically managed. The change in LVEF after surgical management was statistically significant compared to medical management.
  
  
  CONCLUSIONS
  Viability assessment should be performed in patients who present after 12h of acute myocardial infarction or with LV dysfunction due to ischemic heart disease to decide upon appropriate surgical management.
authors: Consultant, Nuclear Medicine and PET-CT, Yashoda Hospital, Hyderabad, India.
authors: Madhur Kumar
authors: MK
authors: Srivatsava
authors: Department of Nuclear Medicine and PET-CT, Apollo Main Hospital, Chennai, India.
authors: M
authors: M
authors: Indirani
authors: Interventional Cardiologist, Dept of Cardiology, Apollo Main Hospital, 21, Greams Lane, Chennai 600006, India. Electronic address: drismurthy@gmail.com.
authors: I
authors: I
authors: Sathyamurthy
authors: Interventional Cardiologist, Dept of Cardiology, Apollo Main Hospital, 21, Greams Lane, Chennai 600006, India.
authors: G
authors: G
authors: Sengottuvelu
authors: Department of Nuclear Medicine and PET-CT, Apollo Main Hospital, Chennai, India.
authors: Avani S
authors: AS
authors: Jain
authors: Department of Nuclear Medicine and PET-CT, Apollo Main Hospital, Chennai, India.
authors: S
authors: S
authors: Shelley
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D011446:Prospective Studies; D019275:Radiopharmaceuticals / Q000494:pharmacology; D015203:Reproducibility of Results; D017256:Technetium Tc 99m Sestamibi / Q000494:pharmacology; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology*
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi
keywords: F-18 FDG cardiac PET-CT; LV dysfunction; Myocardial viability