title: A case of IgG4-related tubulointerstitial nephritis and membranous glomerulonephritis during the clinical course of gastric cancer: Imaging features of IgG4-related kidney disease.
abstract: We describe an 81-year-old man with immunoglobulin G4-related disease (IgG4-RD) presenting with submandibular gland, lymph node, lung, kidney, aortic wall, and prostate lesions with concomitant gastric cancer. After curative surgical treatment of the gastric cancer, corticosteroid therapy for progressively decreasing renal function was started. Before starting steroid therapy, fluorodeoxyglucose positron emission tomography-computed tomography revealed multiple lesions of IgG4-RD but no metastasis of the cancer. However, the patient died 3 months after initiation of corticosteroid therapy because of recurrence of the gastric cancer. In this case, the imaging features of IgG4-tubulointerstitial nephritis dramatically changed during the clinical course of co-existing gastric cancer. The imaging features of the present case may provide clues to the pattern of spread of IgG4 lesions in the kidney.
authors: a Division of Rheumatology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Shigeto
authors: S
authors: Horita
authors: a Division of Rheumatology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Hiroshi
authors: H
authors: Fujii
authors: a Division of Rheumatology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Ichiro
authors: I
authors: Mizushima
authors: a Division of Rheumatology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Yuhei
authors: Y
authors: Fujisawa
authors: a Division of Rheumatology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Satoshi
authors: S
authors: Hara
authors: a Division of Rheumatology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Kazunori
authors: K
authors: Yamada
authors: b Department of Radiology , Kanazawa University Graduate School of Medical Science , Kanazawa , Japan.
authors: Dai
authors: D
authors: Inoue
authors: c Department of Nuclear Medicine , Kanazawa University , Kanazawa , Japan , and.
authors: Kenichi
authors: K
authors: Nakajima
authors: d Department of Human Pathology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Kenichi
authors: K
authors: Harada
authors: a Division of Rheumatology , Kanazawa University Graduate School of Medicine , Kanazawa , Japan.
authors: Mitsuhiro
authors: M
authors: Kawano
mesh_terms: D000369:Aged, 80 and over; D015433:Glomerulonephritis, Membranous / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D006801:Humans; D000077733:Immunoglobulin G4-Related Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D009395:Nephritis, Interstitial / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D000072078:Positron Emission Tomography Computed Tomography; D013274:Stomach Neoplasms / Q000150:complications*
keywords: Fluorodeoxyglucose positron emission tomography; IgG4; Malignancy; Membranous glomerulonephritis; Tubulointerstitial nephritis