title: Proteomics Applications in Dental Derived Stem Cells.
abstract: At present, the existence of a variety of dental derived stem cells has been documented. These cells displayed promising clinical application potential not only for teeth and its surrounding tissue regeneration, but also for other tissues, such as nerve and bone regeneration. Proteomics is an unbiased, global informatics tool that provides information on all protein expression levels as well as post-translational modification in cells or tissues and is applicable to dental derived stem cells research. Over the last decade, considerable progress has been made to study the global proteome, secrotome, and membrane proteome of dental derived stem cells. Here, we present an overview of the proteomics studies in the context of stem cell research. Particular attention is given to dental derived stem cell types as well as current challenges and opportunities. J. Cell. Physiol. 232: 1602-1610, 2017. © 2016 Wiley Periodicals, Inc.
authors: College of Stomatology, Chongqing Medical University, Chongqing, China.|Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, Chongqing, China.|Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
authors: Jie
authors: J
authors: Li
authors: National Engineering Laboratory for Oral Regenerative Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
authors: Weidong
authors: W
authors: Tian
authors: College of Stomatology, Chongqing Medical University, Chongqing, China.|Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, Chongqing, China.|Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China.
authors: Jinlin
authors: J
authors: Song
mesh_terms: D000818:Animals; D003782:Dental Pulp / Q000166:cytology*; D006801:Humans; D020543:Proteome / Q000378:metabolism; D040901:Proteomics / Q000379:methods*; D057905:Stem Cell Research; D013234:Stem Cells / Q000378:metabolism*
chemical_list: D020543:Proteome