title: Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa.
abstract: The migratory phenomenon in Portugal has become one of the main factors for the genetic variability. In the last few years, a new class of autosomal insertion/deletion markers-InDel-has attracted interest in forensic genetics. Since there is no data for InDel markers of Portuguese-speaking African countries (PALOP) immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with at least 30 InDel markers and to compare different groups of individuals/populations. We studied 454 bloodstain samples belonging to immigrant individuals from Angola, Guinea-Bissau, and Mozambique. DNA extraction was performed with the Chelex® 100 method. After extraction, all samples were typed with the Investigator® DIPplex method. Through the obtained results, allelic frequencies show that all markers are at Hardy-Weinberg equilibrium, and we can confirm that those populations show significant genetic distances between themselves, between them, and the host Lisboa population. Because of this, they introduce genetic variability in Lisboa population.
authors: Instituto Nacional de Medicina Legal e Ciências Forenses, Coimbra, Portugal.|Departamento de Genética e Biotecnologia, Universidade de Trás-os-Montes e Alto Douro, Vila Real, Portugal.
authors: Ana
authors: A
authors: Inácio
authors: Instituto Nacional de Medicina Legal e Ciências Forenses, Coimbra, Portugal.|Centro de Ciências Forenses (CENCIFOR), Coimbra, Portugal.
authors: Heloísa Afonso
authors: HA
authors: Costa
authors: Instituto Nacional de Medicina Legal e Ciências Forenses, Coimbra, Portugal.|Centro de Ciências Forenses (CENCIFOR), Coimbra, Portugal.
authors: Cláudia Vieira
authors: CV
authors: da Silva
authors: Instituto Nacional de Medicina Legal e Ciências Forenses, Coimbra, Portugal.|Centro de Ciências Forenses (CENCIFOR), Coimbra, Portugal.
authors: Teresa
authors: T
authors: Ribeiro
authors: Instituto Nacional de Medicina Legal e Ciências Forenses, Coimbra, Portugal.|Centro de Ciências Forenses (CENCIFOR), Coimbra, Portugal.
authors: Maria João
authors: MJ
authors: Porto
authors: Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.|Instituto Superior de Ciências da Saúde Egas Moniz, Monte de Caparica, Portugal.|Centro de Ciências Forenses (CENCIFOR), Coimbra, Portugal.
authors: Jorge Costa
authors: JC
authors: Santos
authors: Departamento de Genética e Biotecnologia, Universidade de Trás-os-Montes e Alto Douro, Vila Real, Portugal.
authors: Gilberto
authors: G
authors: Igrejas
authors: Instituto Nacional de Medicina Legal e Ciências Forenses, Coimbra, Portugal. aamorim@dlinml.mj.pt.|Instituto Superior de Ciências da Saúde Egas Moniz, Monte de Caparica, Portugal. aamorim@dlinml.mj.pt.|Faculdade de Ciências, Universidade de Lisboa, Lisbon, Portugal. aamorim@dlinml.mj.pt.|Centro de Ciências Forenses (CENCIFOR), Coimbra, Portugal. aamorim@dlinml.mj.pt.
authors: António
authors: A
authors: Amorim
mesh_terms: D000349:Africa / Q000208:ethnology; D016172:DNA Fingerprinting; D054242:Emigrants and Immigrants; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D054643:INDEL Mutation; D016133:Polymerase Chain Reaction; D011174:Portugal
chemical_list: D005819:Genetic Markers
keywords: InDel; Lisboa population; PALOP immigrants