title: Increasing dietary oat fibre decreases the permeability of intestinal mucus.
abstract: This study investigates the influence of the dietary fibre β-glucan on nutrient composition and mucus permeability. Pigs were fed a standard diet or a diet containing twice the β-glucan content for 3 days (n = 5 per group), followed by the collection of small intestinal mucus and tissue samples. Samples of the consumed diets were subjected toin vitrodigestion to determine β-glucan release, nutrient profile and assessment of mucus permeability.In vitrodigestion of the diets indicated that 90% of the β-glucan was released in the proximal small intestine. Measurements of intestinal mucus showed a reduction in permeability to 100 nm latex beads and also lipid from the digested enhanced β-glucan diet. The data from this study show for the first time that reducing mass transfer of bile and lipid through the intestinal mucus layer may be one way in which this decrease in bile reabsorption by soluble fibre is enabled.
authors: School of Food Science and Nutrition, University of Leeds, Leeds LS29JT, UK.
authors: Alan
authors: A
authors: Mackie
authors: Institute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UK.
authors: Neil
authors: N
authors: Rigby
authors: Easton Otley College, Easton, Norwich NR9 5DX, UK.
authors: Pascale
authors: P
authors: Harvey
authors: Institute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UK.
authors: Balazs
authors: B
authors: Bajka
keywords: Beta-glucan; Dietary fibre; Diffusion; Mucus; Permeability; Porcine