title: Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography.
abstract: The purpose of this study was to explore the relationship between cerebral amyloid deposition and overall clinical factors including cognitive functions in geriatric depression by using ¹⁸F-florbetaben positron emission tomography. Thirteen subjects aged over 60 years who had a history of major depressive disorder and also had subjective memory complaint were included. Of all subjects, 3 subjects judged as amyloid positive, and the others judged as amyloid negative. Their memory, visuospatial functions and attention abilities were negatively correlated with amyloid deposition in specific brain regions, but their language and recognition abilities were not correlated with any region. The amyloid deposition of the whole brain region was significantly negatively correlated with immediate memory.
authors: Department of Psychiatry, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Korea.
authors: Hye-Geum
authors: HG
authors: Kim
authors: Department of Nuclear Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Korea.
authors: Eun-Jung
authors: EJ
authors: Kong
authors: Department of Psychiatry, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Korea.
authors: Eun-Jin
authors: EJ
authors: Cheon
authors: Department of Nuclear Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
authors: Hae-Won
authors: HW
authors: Kim
authors: Department of Psychiatry, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Korea.
authors: Bon-Hoon
authors: BH
authors: Koo
keywords: Alzheimer disease; Amyloid positron emission tomography; Geriatric depression; Subjective memory complaint