title: Establishment of reference intervals for procalcitonin in healthy pregnant women of Chinese population.
abstract: OBJECTIVE
  To establish reference intervals (RIs) for procalcitonin (PCT) in healthy pregnant women of Chinese population.
  
  
  METHODS
  Serum PCT levels were measured by electrochemiluminescence immunoassay (ECLIA) in 1246 healthy Chinese women, including 124 cases in the first trimester, 128 cases in the second trimester, 125 cases in the third trimester, 125 cases of vaginal delivery, 124 cases at the 3rd day after vaginal delivery, 122 cases at the 10th day after vaginal delivery, 126 cases with Cesarean delivery, 126 cases at the 3rd day after Cesarean delivery, 124 cases at the 10th day after Cesarean delivery, and 122 cases involving non-pregnant women. All cases were independent. The RIs for PCT were defined using nonparametric 95% intervals.
  
  
  RESULTS
  The RIs for PCT were 0.018-0.051μg/L for the first and second trimester; 0.020-0.152μg/L for the third trimester; 0.022-0.195μg/L for vaginal delivery; 0.019-0.021μg/L for Cesarean delivery; 0.049-5.537μg/L and 0.020-0.148μg/L for 3rd and 10th days after vaginal delivery, respectively; 0.022-0.724μg/L and 0.024-0.129μg/L for the 3rd and 10th days after Cesarean delivery, respectively; and 0.015-0.061μg/L for non-pregnant healthy women.
  
  
  CONCLUSIONS
  The RIs for PCT in pregnant women by trimester, days postpartum, and mode of delivery were established, thus providing a clinical reference for doctors.
authors: Department of Obstetrics and Gynecology, Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.
authors: Yun
authors: Y
authors: Hu
authors: Department of Obstetrics and Gynecology, Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.
authors: Mengyuan
authors: M
authors: Yang
authors: Department of Obstetrics and Gynecology, Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.
authors: Yang
authors: Y
authors: Zhou
authors: Department of Obstetrics and Gynecology, Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China. Electronic address: dingyiling_csu@163.com.
authors: Yiling
authors: Y
authors: Ding
authors: Department of clinical Laboratory, Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.
authors: Zhongyuan
authors: Z
authors: Xiang
authors: Department of Obstetrics and Gynecology, Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.
authors: Ling
authors: L
authors: Yu
mesh_terms: D000328:Adult; D044466:Asian People; D015992:Body Mass Index; D002116:Calcitonin / Q000097:blood*; D005260:Female; D006801:Humans; D011247:Pregnancy; D012016:Reference Values
chemical_list: D002116:Calcitonin
keywords: Pregnant women; Procalcitonin; Reference intervals