title: Lipedematous alopecia: clinical and histological analysis of the first male Chinese.
abstract: BACKGROUND
  Lipedematous alopecia (LA) is a rare disorder clinically characterized by a thick boggy scalp and varying severity of hair loss, which primarily occurs in black female adults. In this study, we reported one male adult Chinese diagnosed with lipedematous alopecia for the first time.
  
  
  METHODS
  A Chinese male, aged 20 years old, admitted to Shandong Provincial Hospital for Skin Diseases was diagnosed with LA. Clinical, histological and imaging data were collected and analyzed. Literature review was performed.
  
  
  RESULTS
  Skin biopsy and pathological examination revealed the signs of increased subcutaneous adipose tissue, slight perivascular mononuclear infiltration into superficial dermis, adipocyte disruption and mucin deposition. CT scan demonstrated diffuse thickening of subcutaneous tissue in the occipital region. The symptoms were not significantly alleviated after 6-month combined therapy of prednisone and acupuncture.
  
  
  CONCLUSIONS
  We reported one male Chinese of LA, who was the first case reported in China. Clinical and pathological findings of this case deepened the understanding of LA.
authors: Shandong Provincial Hospital for Skin Diseases, Shandong University, Jinan, 250022 Shandong Province People's Republic of China ; Department of Dermatology, Jining No. 1 People's Hospital, Jining, Shandong Province People's Republic of China.
authors: Wei
authors: W
authors: Wang
authors: Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, No. 27397 Jingshi Road, Jinan, 250022 Shandong Province People's Republic of China.
authors: Guizhi
authors: G
authors: Zhou
authors: Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, No. 27397 Jingshi Road, Jinan, 250022 Shandong Province People's Republic of China.
authors: Yanfang
authors: Y
authors: Zhang
authors: Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, No. 27397 Jingshi Road, Jinan, 250022 Shandong Province People's Republic of China.
authors: Changping
authors: C
authors: Yu
authors: Shandong Provincial Hospital for Skin Diseases, Shandong University, Jinan, 250022 Shandong Province People's Republic of China ; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, No. 27397 Jingshi Road, Jinan, 250022 Shandong Province People's Republic of China.
authors: Furen
authors: F
authors: Zhang
keywords: Histological examination; Lipedematous alopecia; Male; Skin biopsy