title: Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients.
abstract: Objectives.To compare durability and survival after endovascular aneurysm repair (EVAR) and open repair (OR) of abdominal aortic aneurysms (AAAs) in young patients.Material and Methods.A retrospective study was conducted between 2005 and 2014 on all consecutive patients of 60 years of age or younger. Measures considered for analysis were reintervention related to AAA, laparotomy and access vessel injury during EVAR, and all-cause mortality during hospitalization and follow-up.Results.Seventy out of 119 patients were treated by OR (58.8%) and 49 (41.2%) by EVAR, 9 in off-label fashion (18.3%). Technical success was achieved in all cases. No AAA-related death was recorded. Overall in-hospital mortality was zero and the reintervention rate was 2.5% (3/119: 1/70 OR, 2/49 EVAR,p= 0.36). There is no death at 30-day or 1-year follow-up. Thirty-day reintervention rate was 1.6% (2/119; 0/70 OR, 2/49 EVAR,p= 0.16), while the 1-year rate was 2.5% (3/119; 1/70 OR, 2/49 EVAR,p= 0.36). At the mean follow-up of 56.8 ± 42.7 months, mortality and reintervention rates were 5.8% (7/119; 3/70 OR, 4/49 EVAR,p= 0.38) and 10% (12/119; 8/70 OR, 4/49 EVAR,p= 0.39), respectively. The overall reintervention rate, mortality, and freedom from adverse events did not differ between the two groups. No differences in outcome were recorded between patients treated by EVAR in on-label versus off-label fashion.Conclusion.Our (albeit limited) experience suggests that, in an unselected young patient population undergoing elective AAA repair, OR or EVAR can be performed safely with similar immediate and long term outcomes.
authors: Vascular and Endovascular Surgery Unit, Department of Surgery "Paride Stefanini", Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy.
authors: Pasqualino
authors: 0000-0002-1312-1915
authors: P
authors: Sirignano
authors: Vascular and Endovascular Surgery Unit, Department of Surgery "Paride Stefanini", Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy.
authors: Francesco
authors: F
authors: Speziale
authors: Vascular and Endovascular Surgery Unit, Department of Surgery "Paride Stefanini", Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy.
authors: Nunzio
authors: N
authors: Montelione
authors: Vascular and Endovascular Surgery Unit, Department of Surgery "Paride Stefanini", Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy.
authors: Chiara
authors: C
authors: Pranteda
authors: Vascular and Endovascular Surgery Unit, Department of Medicine Surgery and Neurological Sciences, Policlinico Le Scotte, University of Siena, 53100 Siena, Italy.
authors: Giuseppe
authors: G
authors: Galzerano
authors: Vascular and Endovascular Surgery Unit, Department of Surgery "Paride Stefanini", Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy.
authors: Wassim
authors: W
authors: Mansour
authors: Vascular and Endovascular Surgery Unit, Department of Surgery "Paride Stefanini", Policlinico Umberto I, "Sapienza" University of Rome, 00161 Rome, Italy.
authors: Enrico
authors: E
authors: Sbarigia
authors: Vascular and Endovascular Surgery Unit, Department of Medicine Surgery and Neurological Sciences, Policlinico Le Scotte, University of Siena, 53100 Siena, Italy.
authors: Carlo
authors: C
authors: Setacci
mesh_terms: D000704:Analysis of Variance; D017544:Aortic Aneurysm, Abdominal / Q000401:mortality* / Q000601:surgery*; D057510:Endovascular Procedures / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies