title: Recent Perioperative Pharmacological Prevention of Acute Kidney Injury after Cardiac Surgery: A Narrative Review.
abstract: Acute kidney injury (AKI) is a common and severe complication of cardiac surgery, and related rates of both hospitalization and long-term mortality are increasing. A number of studies have explored the preventive effects of perioperative pharmacological therapy on AKI after cardiac surgery. However, the mechanisms of AKI are multifaceted, and no universal treatment has been confirmed as beneficial. We review and analyze several current perioperative pharmacological therapies for AKI after cardiac surgery to identify promising preventive strategies.
authors: Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.
authors: Shurong
authors: S
authors: Li
authors: Medical Center of the Graduate School, Nanchang University, Nanchang, People's Republic of China.
authors: Shufang
authors: S
authors: Fu
authors: Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China.
authors: Yichen
authors: Y
authors: Xiao
authors: Department of Nephrology, The Second Affiliated Hospital of Nanchang University, No. 1, Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China. Ngaosixu@126.com.
authors: Gaosi
authors: G
authors: Xu
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D020927:Dexmedetomidine / Q000627:therapeutic use; D006801:Humans; D006835:Hydrazones / Q000627:therapeutic use; D019990:Perioperative Care / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D011724:Pyridazines / Q000627:therapeutic use; D012307:Risk Factors; D000077464:Simendan
chemical_list: D006835:Hydrazones; D011724:Pyridazines; D000077464:Simendan; D020927:Dexmedetomidine