title: Neuromuscular blockade in the elderly.
abstract: The aim of the presented review is to highlight the clinical problem of postoperative residual curarization (PORC) following general anaesthesia in the elderly. Possible complications of PORC are described along with age-induced changes in pharmacokinetics of long and intermediate-acting neuromuscular blocking agents. This is intended to facilitate the selection and to promote appropriate intraoperative use of muscle relaxants in patients over the age of 65 years.
authors: Department of Anaesthesiology and Intensive Care, Medical University of Łódź, Poland. mic.str@gmail.com.
authors: Michał
authors: M
authors: Stankiewicz-Rudnicki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000762:Anesthesia Recovery Period; D006801:Humans; D019148:Neuromuscular Blockade / Q000009:adverse effects / Q000379:methods*; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology*; D003473:Neuromuscular Nondepolarizing Agents / Q000494:pharmacology; D011183:Postoperative Complications
chemical_list: D009466:Neuromuscular Blocking Agents; D003473:Neuromuscular Nondepolarizing Agents
keywords: elderly patients; muscle relaxants; neuromuscular block; postoperative residual curarization; reversal