title: Current Role of Radiotherapy for Renal-Cell Carcinoma: Review.
abstract: Surgery is the standard of care for patients with renal-cell carcinoma (RCC). Radiotherapy (RT) can decrease the risk of local recurrence after surgery and can lead to excellent outcomes in patients unfit for surgery. We reviewed clinical experience with various forms of RT, including conventional fractionated RT and intraoperative radiotherapy (IORT) as adjunct to surgery, hypofractionated high-dose stereotactic body radiotherapy (SBRT), and particle therapy in unresectable RCC. We discuss future directions for using RT in the treatment of RCC. We encourage clinicians to incorporate RT modalities in prospective clinical trials.
authors: Ulyanovsk Regional Cancer Center, Radiotherapy Department, Ulyanovsk Oblast, Russia. Electronic address: natalieden@hotbox.ru.
authors: Natalia
authors: N
authors: Dengina
authors: Kidney Cancer Research Bureau, Moscow, Russia.
authors: Ilya
authors: I
authors: Tsimafeyeu
authors: Oregon Health and Science University Knight Cancer Institute, Portland, OR.
authors: Timur
authors: T
authors: Mitin
mesh_terms: D002292:Carcinoma, Renal Cell / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D007430:Intraoperative Care; D007680:Kidney Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D000069473:Radiation Dose Hypofractionation; D016634:Radiosurgery; D016896:Treatment Outcome
keywords: Intraoperative radiotherapy; Particle therapy; Radioresistance; Radiosensitivity; Stereotactic body radiotherapy; Targeted therapy