title: Metastatic giant basal cell carcinoma: a case report.
abstract: Basal cell carcinoma is the most common skin cancer, characterised by a slow growing behavior, metastasis are extremely rare, and it occurs in less than 0, 1% of all cases. Giant basal cell carcinoma is a rare form of basal cell carcinoma, more aggressive and defined as a tumor measuring more than 5 cm at its largest diameter. Only 1% of all basal cell carcinoma develops to a giant basal cell carcinoma, resulting of patient's negligence. Giant basal cell carcinoma is associated with higher potential of metastasis and even death, compared to ordinary basal cell carcinoma. We report a case of giant basal cell carcinoma metastaticin lung occurring in a 79 years old male patient, with a fatal evolution after one course of systemic chemotherapy. Giant basal cell carcinoma is a very rare entity, early detection of these tumors could prevent metastasis occurrence and improve the prognosis of this malignancy.
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Khadija
authors: K
authors: Bellahammou
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Asmaa
authors: A
authors: Lakhdissi
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Othman
authors: O
authors: Akkar
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Fadoua
authors: F
authors: Rais
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Benhmidou
authors: B
authors: Naoual
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Ibrahim
authors: I
authors: Elghissassi
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Hind
authors: H
authors: M'rabti
authors: Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Hassan
authors: H
authors: Errihani
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002280:Basal Cell Carcinoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D009362:Neoplasm Metastasis; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents
keywords: Giant basal cell carcinoma; metastasis; prognosis