title: Diastereoselective Intramolecular [3 + 2]-Annulation of Donor-Acceptor Cyclopropane with Imine-Assembling Hexahydropyrrolo[3,2-c]quinolinone Scaffolds.
abstract: An intramolecular [3 + 2]-annulation of amide-linked donor-acceptor cyclopropane with in situ-generated imine is described. As a result, diverse hexahydropyrrolo[3,2-c]quinolinones, as the tricyclic core of martinellines, were efficiently assembled in good to excellent yield (up to 93%) with a good diastereomeric ratio (up to 98:2).
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Jun-An
authors: JA
authors: Xiao
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Jie
authors: J
authors: Li
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Peng-Ju
authors: PJ
authors: Xia
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Zhao-Fang
authors: ZF
authors: Zhou
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Zhao-Xu
authors: ZX
authors: Deng
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Hao-Yue
authors: HY
authors: Xiang
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Xiao-Qing
authors: XQ
authors: Chen
authors: College of Chemistry and Chemical Engineering, Central South University , Changsha 410083, P. R. China.
authors: Hua
authors: H
authors: Yang