title: Does oocyte donation compared with autologous oocyte IVF pregnancies have a higher risk of preeclampsia?
abstract: The aim of this study was to evaluate whether pregnancies resulting from oocyte donation have a higher risk of preeclampsia compared with pregnancies after IVF using autologous oocytes. Propensity score matching on maternal age and parity was carried out on a one to one basis, and a total of 144 singleton pregnancies resulting in delivery beyond 22 gestational weeks, achieved by oocyte donation, were compared with 144 pregnancies achieved through IVF and intracytoplasmic sperm injection with the use of autologous oocytes. All pregnancies were achieved after fresh embryo transfer. Obstetric and neonatal outcomes were compared for each pregnancy. Singleton pregnancies after oocyte donation were associated with a significantly higher risk for preeclampsia (OR 2.4, CI 1.02 to 5.8; P = 0.046), as well as for pregnancy-induced hypertension (OR 5.3, CI 1.1 to 25.2; P = 0.036), and caesarean delivery (OR 2.3, CI 1.4 to 3.7; P = 0.001) compared with pregnancies using autologous oocytes.
authors: Fertility Clinic, Department of Obstetrics and Gynecology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium. Electronic address: nonika.tarlatzi@gmail.com.
authors: Theoni B
authors: TB
authors: Tarlatzi
authors: Fertility Clinic, Department of Obstetrics and Gynecology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
authors: Romain
authors: R
authors: Imbert
authors: Fertility Clinic, Department of Obstetrics and Gynecology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
authors: Beatriz
authors: B
authors: Alvaro Mercadal
authors: Fertility Clinic, Department of Obstetrics and Gynaecology, Erasme Hospital, Research Laboratory on Human Reproduction, Université Libre de Bruxelles, Brussels, Belgium.
authors: Isabelle
authors: I
authors: Demeestere
authors: Women's and Children's Health, St George Hospital, University of New South Wales, NSW, Australia.
authors: Christos A
authors: CA
authors: Venetis
authors: Fertility Clinic, Department of Obstetrics and Gynecology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
authors: Yvon
authors: Y
authors: Englert
authors: Fertility Clinic, Department of Obstetrics and Gynecology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
authors: Anne
authors: A
authors: Delbaere
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D046110:Hypertension, Pregnancy-Induced; D007246:Infertility / Q000150:complications*; D018587:Oocyte Donation; D009865:Oocytes / Q000166:cytology*; D010053:Ovary / Q000502:physiology; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000453:epidemiology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012306:Risk; D020554:Sperm Injections, Intracytoplasmic
keywords: neonatal outcomes; obstetric outcomes; oocyte donation; preeclampsia; pregnancy-induced hypertension