title: Impact of glucose control on early vein graft failure after coronary artery bypass grafting: one-month angiographic results.
abstract: To identify factors that determine early saphenous vein graft failure (VGF) within 1 month after coronary artery bypass grafting (CABG).
  
  
  
  Seven hundred forty-nine consecutive patients underwent primary isolated CABG with saphenous vein grafts at three Japanese centres from 1 January 2005 to 31 December 2014. According to angiographic findings within 1 month of CABG surgery, 63 patients (8.4%) developed early VGF. We examined the relationships between variables and early VGF by using multivariable logistic regression analysis.
  
  
  
  The preoperative clinical characteristics were similar between patients with and without early VGF, except for median preoperative haemoglobin A1c levels, which were significantly higher among patients with early VGF (6.7 vs 6.4%, P = 0.046). Additionally, anastomosis to the vessel with chronic total obstruction was performed more frequently among patients with early VGF (22/63 [34.9%] vs 140/686 [20.4%], P = 0.007), and myocardial infarction during the hospital admission occurred more frequently among patients with early VGF (4/63 [6.3%] vs 2/686 [0.3%], P < 0.0001). Results of multivariable analysis showed that the preoperative haemoglobin A1c level was associated with early VGF (odds ratio per unit increase, 1.30; 95% confidence interval, 1.06-1.60; P = 0.013).
  
  
  
  An increased preoperative haemoglobin A1c level was strongly associated with early VGF after CABG. Thus, VGF happened more frequently in patients with poorly controlled diabetes mellitus.
authors: Department of Cardiovascular Surgery, Toyohashi Heart Center, Toyohashi, Japan.
authors: Shinji
authors: S
authors: Ogawa
authors: Department of Cardiovascular Surgery, Nagoya Heart Center, Nagoya, Japan.
authors: Yasuhide
authors: Y
authors: Okawa
authors: Department of Cardiovascular Surgery, Toyohashi Heart Center, Toyohashi, Japan.
authors: Koshi
authors: K
authors: Sawada
authors: Department of Cardiovascular Surgery, Gifu Heart Center, Gifu, Japan.
authors: Yusuke
authors: Y
authors: Motoji
authors: Department of Cardiovascular Surgery, Toyohashi Heart Center, Toyohashi, Japan.
authors: Yoshihiro
authors: Y
authors: Goto
authors: Department of Cardiovascular Surgery, Nagoya Heart Center, Nagoya, Japan.
authors: Arishige
authors: A
authors: Kimura
authors: Department of Cardiovascular Surgery, Nagoya Heart Center, Nagoya, Japan.
authors: Mototsugu
authors: M
authors: Tamaki
authors: Department of Cardiovascular Surgery, Nagoya Heart Center, Nagoya, Japan.
authors: Yutaka
authors: Y
authors: Koyama
authors: Department of Cardiovascular Surgery, Toyohashi Heart Center, Toyohashi, Japan.
authors: Masanori
authors: M
authors: Yamamoto
authors: Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan.
authors: Toshiaki
authors: T
authors: Otsuka
authors: Department of Cardiovascular Surgery, Gifu Heart Center, Gifu, Japan.
authors: Takayoshi
authors: T
authors: Kato
authors: Department of Cardiovascular Surgery, Toyohashi Heart Center, Toyohashi, Japan.
authors: Syunsuke
authors: S
authors: Fukaya
authors: Department of Cardiovascular Surgery, Gifu Heart Center, Gifu, Japan.
authors: Tomohiro
authors: T
authors: Tsunekawa
authors: Department of Cardiovascular Surgery, Nagoya Heart Center, Nagoya, Japan.
authors: Hideki
authors: H
authors: Kitamura
authors: Department of Cardiovascular Surgery, Gifu Heart Center, Gifu, Japan.
authors: Shinji
authors: S
authors: Tomita
authors: Department of Cardiovascular Surgery, Toyohashi Heart Center, Toyohashi, Japan.
authors: Takahiko
authors: T
authors: Suzuki
mesh_terms: D000368:Aged; D001786:Blood Glucose; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000097:blood* / Q000000981:diagnostic imaging / Q000601:surgery*; D048909:Diabetes Complications / Q000097:blood / Q000150:complications; D005260:Female; D006085:Graft Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D012501:Saphenous Vein / Q000637:transplantation; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D001786:Blood Glucose
keywords: Coronary artery bypass graft surgery; Coronary disease; Diabetes mellitus; Myocardial revascularization; Saphenous vein graft