title: Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra.
authors: Department of Dermatology, Pisa University, Pisa, Italy.
authors: T
authors: T
authors: Oranges
authors: Division of Rheumatology, Bambino Gesu Children's Hospital, IRCCS, Rome, Italy.
authors: A
authors: A
authors: Insalaco
authors: Division of Dermatology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
authors: A
authors: A
authors: Diociaiuti
authors: Division of Dermatology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
authors: C
authors: C
authors: Carnevale
authors: Department of Cellular Biotechnologies and Hematology, Section of Molecular Genetics, Sapienza University, Rome, Italy.
authors: R
authors: R
authors: Strippoli
authors: Division of Dermatology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
authors: G
authors: G
authors: Zambruno
authors: Department of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
authors: P
authors: P
authors: Tomà
authors: Division of Dermatology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
authors: M
authors: M
authors: El Hachem
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy* / Q000209:etiology; D020083:Acquired Hyperostosis Syndrome / Q000150:complications / Q000188:drug therapy*; D000293:Adolescent; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D003875:Drug Eruptions / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein / Q000627:therapeutic use*; D015474:Isotretinoin / Q000009:adverse effects*; D008297:Male; D012074:Remission Induction; D012720:Severity of Illness Index
chemical_list: D018501:Antirheumatic Agents; D053590:Interleukin 1 Receptor Antagonist Protein; D015474:Isotretinoin