title: Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality?
abstract: The United Kingdom population is ageing. Half of patients requiring an emergency laparotomy are aged over 70, 20 % die within 30 days, and less than half receive good care. Frailty and delay in management are associated with poor surgical outcomes. P-POSSUM risk scoring is widely accepted, but its validity in patients aged over 70 undergoing emergency laparotomy is unclear.
  
  
  
  To assess if P-POSSUM risk stratification reliably predicts inpatient mortality in this group and establish whether those who died within 30 days received delayed care.
  
  
  
  Observational study of consecutive patients aged 70 and over fulfilling the National Emergency Laparotomy Audit criteria from a tertiary hospital. The predictive value of pre-operative P-POSSUM, ASA, lactate and other routine variables was assessed. Surgical review, decision to operate, consultant surgical review, antibiotic prescription, laparotomy and discharge or death time points were assessed by 30-day survival.
  
  
  
  One hundred and ninety-three patients were included. This represented 46.28 % of those undergoing an emergency laparotomy in our centre. Pre-operative P-POSSUM scoring, ASA grade and lactate were moderate predictors of mortality (AUC 0.784 and 0.771, respectively, lactate AUC 0.705, all p ≤ 0.001). No correlation existed between pre-operative P-POSSUM and days to death (p = 0.209), nor were there delays in key management timings in those who died in 30 days.
  
  
  
  P-POSSUM scoring may predict inpatient mortality with moderate discrimination. Addition of frailty scoring in this high-risk group might better identify those with a high risk of mortality after emergency laparotomy and would be a fertile area for further research.
authors: Emergency General Surgery Department, Southampton General Hospital, Southampton, UK. a.sharrock14@imperial.ac.uk.|Inflammation, Repair and Development Section, National Heart and Lung Institute, Imperial College, London, UK. a.sharrock14@imperial.ac.uk.
authors: Anna E
authors: AE
authors: Sharrock
authors: Anaesthetics Department, Southampton General Hospital, Southampton, UK.
authors: Jenny
authors: J
authors: McLachlan
authors: Anaesthetics Department, Southampton General Hospital, Southampton, UK.|General Intensive Care Department, Southampton General Hospital, Southampton, UK.
authors: Robert
authors: R
authors: Chambers
authors: Emergency General Surgery Department, Southampton General Hospital, Southampton, UK.
authors: Ian S
authors: IS
authors: Bailey
authors: Emergency General Surgery Department, Southampton General Hospital, Southampton, UK.
authors: James
authors: J
authors: Kirkby-Bott
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D004630:Emergencies; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D007813:Laparotomy / Q000401:mortality*; D008297:Male; D018570:Risk Assessment; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D019344:Lactic Acid