title: Fournier's Gangrene and Negative Pressure Wound Therapy: A Case Report.
abstract: Fournier's gangrene is a rare disease that affects the genital, abdominal, and perineal regions and leads to death if not treated promptly.
  
  
  
  A 42-year-old, obese woman presented to the authors' department affected by Fournier's gangrene. In order to treat her abdominal and genital regions, the authors performed a surgical debridement followed by combined therapy with antibiotics and topical negative pressure wound therapy (NPWT) with instillation plus saline solution.
  
  
  
  The combined therapy, but most of all the application of the NPWT, cleaned and decontaminated the wounds. As a direct result of this decontamination, after 20 days, the patient was able to undergo surgery; after 40 days of follow-up, there was no sign of recurrence.
  
  
  
  Negative pressure wound therapy can be a good and useful treatment in the therapy of serious diseases and for the wound bed preparation in advance of surgery.
authors: Vincenzo
authors: V
authors: Vindigni
authors: Carlotta
authors: C
authors: Scarpa
authors: Erica
authors: E
authors: Dalla Venezia
authors: Franco
authors: F
authors: Bassetto
mesh_terms: D000005:Abdomen / Q000473:pathology*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods*; D005260:Female; D018934:Fournier Gangrene / Q000473:pathology / Q000628:therapy*; D005831:Genital Diseases, Female / Q000473:pathology / Q000628:therapy*; D006801:Humans; D054843:Negative-Pressure Wound Therapy; D009765:Obesity; D010502:Perineum / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents