title: Toward an Evidence-Based, Operational Definition of Treatment-Resistant Depression: When Enough Is Enough.
authors: Washington University School of Medicine, St Louis, Missouri2John Cochran Veterans Affairs Medical Center, St Louis, Missouri.
authors: Charles R
authors: CR
authors: Conway
authors: Medical University of South Carolina, Charleston4Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina.
authors: Mark S
authors: MS
authors: George
authors: Columbia University, New York, New York.
authors: Harold A
authors: HA
authors: Sackeim
mesh_terms: D000928:Antidepressive Agents / Q000008:administration & dosage; D061218:Depressive Disorder, Treatment-Resistant / Q000628:therapy*; D004351:Drug Resistance; D019317:Evidence-Based Medicine; D006801:Humans; D019458:Insurance Coverage; D016032:Randomized Controlled Trials as Topic
chemical_list: D000928:Antidepressive Agents