title: Differentiation of essential oils in Atractylodes lancea and Atractylodes koreana by gas chromatography with mass spectrometry.
abstract: Atractylodes rhizome is a valuable traditional Chinese medicinal herb that comprises complex several species whose essential oils are the primary pharmacologically active component. Essential oils of Atractylodes lancea and Atractylodes koreana were extracted by hydrodistillation, and the yield was determined. The average yield of essential oil obtained from A. lancea (2.91%) was higher than that from A. koreana (2.42%). The volatile components of the essential oils were then identified by a gas chromatography with mass spectrometry method that demonstrated good precision. The method showed clear differences in the numbers and contents of volatile components between the two species. 41 and 45 volatile components were identified in A. lancea and A. koreana, respectively. Atractylon (48.68%) was the primary volatile component in A. lancea, while eudesma-4(14)-en-11-ol (11.81%) was major in A. koreana. However, the most significant difference between A. lancea and A. koreana was the major component of atractylon and atractydin. Principal component analysis was utilized to reveal the correlation between volatile components and species, and the analysis was used to successfully discriminate between A. lancea and A. koreana samples. These results suggest that different species of Atractylodes rhizome may yield essential oils that differ significantly in content and composition.
authors: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.|Pharmacy College, Liaoning Medical University, Jinzhou, China.
authors: Qiutao
authors: Q
authors: Liu
authors: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.|Pharmacy College, Liaoning Medical University, Jinzhou, China.
authors: Shanshan
authors: S
authors: Zhang
authors: Chia Tai Tianqing Pharmaceutical Group Co., Ltd, Nanjing, China.
authors: Xihui
authors: X
authors: Yang
authors: PLA Institute of Chinese Materia Medica, 302 Hospital of People's Liberation Army, Beijing, China.
authors: Ruilin
authors: R
authors: Wang
authors: Pharmacy College, Liaoning Medical University, Jinzhou, China.
authors: Weiying
authors: W
authors: Guo
authors: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
authors: Weijun
authors: W
authors: Kong
authors: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
authors: Meihua
authors: M
authors: Yang
mesh_terms: D031174:Atractylodes / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D013058:Mass Spectrometry; D009822:Oils, Volatile / Q000032:analysis*; D010938:Plant Oils / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; D010938:Plant Oils
keywords: Atractylodes rhizome; Essential oils; Multicomponent analysis; Principal component analysis; Traditional Chinese medicine