title: Tarsal Glandular Hyperplasia in Pachydermoperiostosis and Implications for Ptosis Correction.
abstract: Pachydermoperiostosis is a rare genetic disease that causes major bone and skin changes. Severe ptosis is a prominent finding in this peculiar condition. We report here 2 patients with typical features of pachydermoperiostosis. Their tarsal plates were enlarged and infiltrated by sebaceous gland tissue. One patient also displayed diffuse intratarsal lacrimal gland hyperplasia. As far as we know, this is the first report of ectopic lacrimal tissue in pachydermoperiostosis. Tarsal and skin morphologic changes should be addressed during ptosis correction in these patients.
authors: *Division of Oculoplastic and Orbit, Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery; and †Department of Pathology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
authors: Marlos R L
authors: MRL
authors: Silva
authors: Adriano
authors: A
authors: Baccega
authors: Ana Filipa
authors: AF
authors: Duarte
authors: Fernando
authors: F
authors: Chahud
authors: Antonio Augusto V
authors: AAV
authors: Cruz
mesh_terms: D000328:Adult; D001706:Biopsy; D019882:Blepharoplasty / Q000379:methods*; D001763:Blepharoptosis / Q000209:etiology / Q000601:surgery; D005143:Eyelids / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D010004:Osteoarthropathy, Primary Hypertrophic / Q000150:complications / Q000175:diagnosis