title: [The significance of peripheral blood natural killer cell surface CD107a,NKG2D and serum sMICA in patients with extranodal NK/T cell lymphoma, nasal type].
abstract: The expression of CD107a,NKG2D on the surface of natural killer (NK) cells and serum soluble major histocompatibility complex class Ⅰ chain-related A (sMICA) level in patients with extranodal NK/T cell lymphoma, nasal type (ENKL) were detected.We found that CD107aexpression was reduced on the surface of NK cells, suggesting impaired NK cell activity in ENKL patients, which may result from decreased NKG2D expression.
authors: Department of Hematology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: J X
authors: JX
authors: Liu
authors: J W
authors: JW
authors: Wang
authors: X Y
authors: XY
authors: Cui
mesh_terms: D015395:Histocompatibility Antigens Class I / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology* / Q000378:metabolism*; D054391:Lymphoma, Extranodal NK-T-Cell / Q000097:blood / Q000276:immunology* / Q000473:pathology; D055655:NK Cell Lectin-Like Receptor Subfamily K / Q000378:metabolism*; D009669:Nose Neoplasms / Q000097:blood / Q000276:immunology* / Q000473:pathology
chemical_list: D015395:Histocompatibility Antigens Class I; C527085:KLRK1 protein, human; C099187:MHC class I-related chain A; D055655:NK Cell Lectin-Like Receptor Subfamily K