title: [Pharmacokinetics of selective estrogen receptor modulators(SERMs).]
abstract: Selective estrogen receptor modulators(SERMs), or estrogen receptor agonists/antagonists(ERAAs), are a class of compounds that function as estrogen receptor(ER)agonists or antagonists tissue-dependently. Two types of SERMs are currently used in Japan to treat osteoporosis, raloxifene(RLX:Evista)and bazedoxifene(BZA:Viviant). This article describes the pharmacokinetics of these two drugs.
authors: Department of Women's Health, Tokyo Medical and Dental University, Japan.
authors: Masakazu
authors: M
authors: Terauchi
mesh_terms: D000284:Administration, Oral; D000375:Aging; D005260:Female; D006801:Humans; D007674:Kidney Diseases; D008297:Male; D010024:Osteoporosis / Q000188:drug therapy; D017698:Postmenopause; D020845:Selective Estrogen Receptor Modulators / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics* / Q000627:therapeutic use; D012727:Sex Characteristics
chemical_list: D020845:Selective Estrogen Receptor Modulators