title: Immunity Status of Blood Donors RegardingToxoplasma gondiiInfection in a Low-Income District of Abidjan, Côte d'Ivoire, West Africa.
abstract: Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known,Toxoplasma gondiican be transmitted during transplantation or blood transfusion. The aim of this study is to determine the prevalence of IgG and IgMToxoplasma gondiiand to estimate the potential risk by blood products.Methods. This is a cross-sectional study on the research forToxoplasma gondiiantibodies (IgG and IgM) blood donors performed by ELISA.Results. An overall seroprevalence ofToxoplasma gondiiamong blood donors recruited was 67.92% (n= 72). Among these, 68 haveToxoplasma gondiiIgG (64.15%), 12Toxoplasma gondiiIgM (11.32%), and 4 (3.77%) both. The risk varies between 8 for 100000 and 172 for 100000 donations.Conclusion. The need to strengthen security measures for people multitransfused, immunocompromised, and pregnant women to reduce the transmission of toxoplasmosis is important.
authors: Immunology and Allergology Department, UFR Medical Sciences in Abidjan, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire; National Blood Transfusion Center, Abidjan, Côte d'Ivoire.
authors: Liliane
authors: 0000-0002-2345-5687
authors: L
authors: Siransy
authors: Immunology and Allergology Department, UFR Medical Sciences in Abidjan, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire.
authors: Sery Romuald
authors: SR
authors: Dasse
authors: Medical and Technical Parasitology Department, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire.
authors: Serge Pacôme
authors: SP
authors: Dou Gonat
authors: National Blood Transfusion Center, Abidjan, Côte d'Ivoire.
authors: Antoinette
authors: A
authors: Legbedji
authors: Immunology and Allergology Department, UFR Medical Sciences in Abidjan, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire.
authors: Koffi
authors: K
authors: N'guessan
authors: Immunology and Allergology Department, UFR Medical Sciences in Abidjan, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire.
authors: Patricia Ama
authors: PA
authors: Kouacou
authors: Immunology and Allergology Department, UFR Medical Sciences in Abidjan, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire.
authors: Richard
authors: R
authors: Yeboah
authors: Medical and Technical Parasitology Department, Felix Houphouet Boigny University, Abidjan, Côte d'Ivoire.
authors: Hervé
authors: H
authors: Menan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000913:Antibodies, Protozoan / Q000097:blood / Q000276:immunology; D001782:Blood Donors; D007560:Cote d'Ivoire / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D008297:Male; D008875:Middle Aged; D062486:Public Health Surveillance; D016036:Seroepidemiologic Studies; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology* / Q000276:immunology* / Q000469:parasitology; D055815:Young Adult
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007075:Immunoglobulin M