title: Selective arterial spin labeling in conjunction with phase-contrast acquisition for the simultaneous visualization of morphology, flow direction, and velocity of individual arteries in the cerebrovascular system.
abstract: In various cerebrovascular diseases the visualization of individual arteries and knowledge about their hemodynamic properties, like flow velocity and direction, can become important for an accurate diagnosis. Magnetic resonance angiography methods are intended to acquire this information, but often a single acquisition is not sufficient to retrieve all of this desired information.
  
  
  
  Using selective arterial spin labeling (ASL) methods, a single artery of interest can be tagged and visualized, whereas quantitative information about hemodynamics can be retrieved using phase-contrast techniques that are often limited regarding their selectivity. In this study, a method that allows for velocity mapping of individual arteries by incorporating phase-contrast preparation into selective ASL angiography measurements is presented. Several postprocessing steps are required to generate velocity and directional-encoded maps of selected arteries from the data acquired in a single scan.
  
  
  
  The method was successfully evaluated in healthy volunteers, and a first application in two selected patients is presented. In one patient, an aneurysm of the middle cerebral artery is investigated, and in the second patient it is used to visualize an arterio-venous malformation.
  
  
  
  Selective ASL imaging in conjunction with phase-contrast acquisition allows for investigating hemodynamic properties of individual arteries. Magn Reson Med 78:1469-1475, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
authors: Clinic for Radiology and Neuroradiology, UKSH Campus Kiel, Kiel, Germany.
authors: Thomas
authors: T
authors: Lindner
authors: Clinic for Radiology and Neuroradiology, UKSH Campus Kiel, Kiel, Germany.
authors: Naomi
authors: N
authors: Larsen
authors: Clinic for Radiology and Neuroradiology, UKSH Campus Kiel, Kiel, Germany.
authors: Olav
authors: O
authors: Jansen
authors: Philips GmbH Innovative Technologies, Research Laboratories, Hamburg, Germany.
authors: Michael
authors: M
authors: Helle
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology*; D002536:Cerebral Arteries / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged
keywords: angiography; arterial spin labeling; phase contrast; super selective; velocity mapping