title: The Clinical Application of Hydrogen as a Medical Treatment.
abstract: In recent years, it has become evident that molecular hydrogen is a particularyl effective treatment for various disease models such as ischemia-reperfusion injury; as a result, research on hydrogen has progressed rapidly. Hydrogen has been shown to be effective not only through intake as a gas, but also as a liquid medication taken orally, intravenously, or locally. Hydrogen's effectiveness is thus multifaceted. Herein we review the recent research on hydrogen-rich water, and we examine the possibilities for its clinical application. Now that hydrogen is in the limelight as a gaseous signaling molecule due to its potential ability to inhibit oxidative stress signaling, new research developments are highly anticipated.
authors: Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
authors: Atsuyoshi
authors: A
authors: Iida
authors: Nobuyuki
authors: N
authors: Nosaka
authors: Tetsuya
authors: T
authors: Yumoto
authors: Emily
authors: E
authors: Knaup
authors: Hiromichi
authors: H
authors: Naito
authors: Chihiro
authors: C
authors: Nishiyama
authors: Yasuaki
authors: Y
authors: Yamakawa
authors: Kohei
authors: K
authors: Tsukahara
authors: Michihisa
authors: M
authors: Terado
authors: Keiji
authors: K
authors: Sato
authors: Toyomu
authors: T
authors: Ugawa
authors: Atsunori
authors: A
authors: Nakao
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use; D005740:Gases / Q000627:therapeutic use; D006801:Humans; D006859:Hydrogen / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D018384:Oxidative Stress; D015398:Signal Transduction / Q000502:physiology
chemical_list: D000975:Antioxidants; D005740:Gases; D006859:Hydrogen