title: Antimicrobial potential of green synthesized CeO2nanoparticles fromOlea europaealeaf extract.
abstract: This article reports the green fabrication of cerium oxide nanoparticles (CeO2NPs) usingOlea europaealeaf extract and their applications as effective antimicrobial agents.O. europaealeaf extract functions as a chelating agent for reduction of cerium nitrate. The resulting CeO2NPs exhibit pure single-face cubic structure, which is examined by X-ray diffraction, with a uniform spherical shape and a mean size 24 nm observed through scanning electron microscopy and transmission electron microscopy. Ultraviolet-visible spectroscopy confirms the characteristic absorption peak of CeO2NPs at 315 nm. Fourier transform infrared spectroscopy reflects stretching frequencies at 459 cm-1, showing utilization of natural components for the production of NPs. Thermal gravimetric analysis predicts the successful capping of CeO2NPs by bioactive molecules present in the plant extract. The antimicrobial studies show significant zone of inhibition against bacterial and fungal strains. The higher activities shown by the green synthesized NPs than the plant extract lead to the conclusion that they can be effectively used in biomedical application. Furthermore, reduction of cerium salt by plant extract will reduce environmental impact over chemical synthesis.
authors: Department of Biotechnology, Virtual University of Pakistan, Lahore, Pakistan.
authors: Qaisar
authors: Q
authors: Maqbool
authors: Department of Biotechnology, Virtual University of Pakistan, Lahore, Pakistan.
authors: Mudassar
authors: M
authors: Nazar
authors: Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
authors: Sania
authors: S
authors: Naz
authors: National Institute of Vacuum Science and Technology (NINVAST), Islamabad, Pakistan.
authors: Talib
authors: T
authors: Hussain
authors: Department of Biotechnology and Bioinformatics Lab., International Islamic University, Islamabad, Pakistan.
authors: Nyla
authors: N
authors: Jabeen
authors: Department of Chemistry, University of Sargodha, Sargodha, Pakistan.
authors: Rizwan
authors: R
authors: Kausar
authors: Department of Biotechnology and Bioinformatics Lab., International Islamic University, Islamabad, Pakistan.
authors: Sadaf
authors: S
authors: Anwaar
authors: Department of Physics, International Islamic University, Islamabad, Pakistan; Interdisciplinary Research Organization, University of Chakwal (UOC), Chakwal, Pakistan.
authors: Fazal
authors: F
authors: Abbas
authors: Department of Physics, International Islamic University, Islamabad, Pakistan.
authors: Tariq
authors: T
authors: Jan
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D002563:Cerium / Q000737:chemistry*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D055772:Green Chemistry Technology; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry; D031658:Olea / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts; C032786:cerium nitrate; D002563:Cerium; C030583:ceric oxide
keywords: FTIR; SEM; TEM; XRD; antibacterial; antifungal; green fabrication; nanomedicine