title: The addicted brain: imaging neurological complications of recreational drug abuse.
abstract: Recreational drug abuse represents a serious public health problem. Neuroimaging traditionally played a secondary role in this scenario, where it was limited to detecting acute vascular events. However, thanks to advances in knowledge about disease and in morphological and functional imaging techniques, radiologists have now become very important in the diagnosis of acute and chronic neurological complications of recreational drug abuse. The main complications are neurovascular disease, infection, toxicometabolic disorders, and brain atrophy. The nonspecific symptoms and denial of abuse make the radiologist's involvement fundamental in the management of these patients. Neuroimaging makes it possible to detect early changes and to suggest an etiological diagnosis in cases with specific patterns of involvement. We aim to describe the pattern of abuse and the pathophysiological mechanisms of the drugs with the greatest neurological repercussions as well as to illustrate the depiction of the acute and chronic cerebral complications on conventional and functional imaging techniques.
authors: Área Clínica de Imagen Médica, Hospital Universitario y Politécnico La Fe, Valencia, España. Electronic address: montoyafilardi@gmail.com.
authors: A
authors: A
authors: Montoya-Filardi
authors: Área Clínica de Imagen Médica, Hospital Universitario y Politécnico La Fe, Valencia, España.
authors: M
authors: M
authors: Mazón
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging* / Q000187:drug effects; D001927:Brain Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*; D005260:Female; D006801:Humans; D013287:Illicit Drugs / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D059906:Neuroimaging; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D013287:Illicit Drugs
keywords: Atrofia; Atrophy; Biochemical mechanisms; Drogas de abuso; Functional imaging; Hemorragia; Imagen funcional; Infarction; Infarto; Leucoencefalopatía; Leukoencephalopathy; Magnetic resonance imaging; Marchiafava-Bignami; Mecanismo bioquímico; Recreational drugs; Resonancia magnética; hemorrhage