title: Mg substituted apatite coating from alkali conversion of acidic calcium phosphate.
abstract: In this work, two solutions were developed: the first, rich in Ca2+, PO43-ions and the second, rich in Ca2+, PO43-and Mg2+, defined as Mg-modified precursor solution. For each Mg-modified precursor solution, the concentrations of Mg2+ions were progressively increased by 5%, 10% and 15%wt. The aims of this research were to investigate the influence of magnesium ions substitution in calcium phosphate coatings on titanium surface and to evaluate these coatings by bioactivity assay in McCoy culture medium. The obtained coatings were characterized by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) analysis, and the presence of Mg ions was confirmed by the inductively coupled plasma atomic emission spectroscopy (ICP) analysis. In vitro bioactivity assay in McCoy culture medium showed bioactivity after 14days in incubation for the HA and 10% Mg-monetite coatings. The high chemical stability of Mg-HA coatings was verified by the bioactivity assays, and no bone-like apatite deposition, characteristic of bioactivity, was observed for Mg-HA coatings, for the time period used in this study.
authors: Military Institute of Engineering-IME, Pça. Gen. Tiburcio, 80, P. Vermelha, Urca, Rio de Janeiro, R.J., Brazil. Electronic address: dnr.navarro@gmail.com.
authors: Daniel
authors: D
authors: Navarro da Rocha
authors: Military Institute of Engineering-IME, Pça. Gen. Tiburcio, 80, P. Vermelha, Urca, Rio de Janeiro, R.J., Brazil.
authors: Leila Rosa de Oliveira
authors: LR
authors: Cruz
authors: Rio de Janeiro State University - UERJ, Rio de Janeiro, R.J., Brazil.
authors: José Brant
authors: JB
authors: de Campos
authors: Military Institute of Engineering-IME, Pça. Gen. Tiburcio, 80, P. Vermelha, Urca, Rio de Janeiro, R.J., Brazil.
authors: Rubens L Santana Blazutti
authors: RL
authors: Marçal
authors: Department of Biomaterials and Biomimetics, New York University College of Dentistry (NYU), New York, NY, USA.
authors: Dindo Q
authors: DQ
authors: Mijares
authors: Department of Biomaterials and Biomimetics, New York University College of Dentistry (NYU), New York, NY, USA.
authors: Paulo G
authors: PG
authors: Coelho
authors: Military Institute of Engineering-IME, Pça. Gen. Tiburcio, 80, P. Vermelha, Urca, Rio de Janeiro, R.J., Brazil.
authors: Marcelo H
authors: MH
authors: Prado da Silva
mesh_terms: D000143:Acids / Q000737:chemistry; D000468:Alkalies / Q000737:chemistry*; D001031:Apatites / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D007477:Ions; D008274:Magnesium / Q000737:chemistry*; D008970:Molecular Weight; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000143:Acids; D000468:Alkalies; D001031:Apatites; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D007477:Ions; C020243:calcium phosphate; D008274:Magnesium; C494366:calcium phosphate, dibasic, dihydrate
keywords: Bioactivity; Brushite; Coating; Hydroxyapatite; Magnesium; Monetite