title: What Role Does Allergy Play in Chronic Ear Disease and Laryngitis?
abstract: IgE-mediated allergy plays a well-established role in both nasal and pulmonary diseases due to the common epithelium and shared mediator responses of the upper and lower airways. This "unified airway" concept has also been described in other sites within the head and neck that contain similar respiratory mucosa: the middle ear and the larynx. This review will highlight the data suggesting a role for IgE-mediated allergic disease in chronic laryngopharyngeal and middle ear disease and the role for allergy testing to aid in diagnosis and treatment of these disorders.
authors: Department of Otolaryngology- Head and Neck Surgery, Boston University School of Medicine, 820 Harrison Avenue, Boston, MA, 02118, USA.
authors: Michael P
authors: MP
authors: Platt
authors: Department of Otolaryngology- Head and Neck Surgery, Boston University School of Medicine, 820 Harrison Avenue, Boston, MA, 02118, USA. christopher.brook@bmc.org.
authors: Christopher D
authors: CD
authors: Brook
authors: Department of Otolaryngology- Head and Neck Surgery, Boston University School of Medicine, 820 Harrison Avenue, Boston, MA, 02118, USA.
authors: Jacob
authors: J
authors: Kuperstock
authors: Department of Otolaryngology - Head and Neck Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
authors: John H
authors: JH
authors: Krouse
mesh_terms: D002908:Chronic Disease; D004427:Ear Diseases / Q000209:etiology*; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D007827:Laryngitis / Q000209:etiology*
keywords: Allergic laryngitis; Allergic rhinitis; Chronic ear disease; IgE-mediated allergy; Middle ear disease; Unified airway