title: Synthesis and physico-chemical characterization of modified starches from banana (Musa AAB) and its biological activities in diabetic rats.
abstract: This study describes a simple method of preparation and physico-chemical properties of modified starches (type-3 resistant starches) from banana (Musa AAB), and the modified starches investigated as functional food with a beneficial effect on type-2 diabetes. RS3 was prepared using a method combined with debranching modification and physical modification; native and modifies starches were characterized by scanning electron microscope (SEM), powder X-ray diffraction (XRD), differential scanning calorimetry (DSC) and rapid visco analyzer (RVA). Use of the enzymatic and physical modification methodology, improved the yield of RS (26.62%) from Musa AAB. A reduced viscosity and swelling power; increased transition temperatures, water absorption capacity and solubility index with B-type crystalline pattern and loss of granular appearance were observed during the debranching modification and physical modification. The modified starches exhibited beneficial health effects in diabetic and HFD rats who consumed it. These results recommend that dietary feeding of RS3 was effective in the regulation of glucose and lipid profile in serum and suppressing the oxidative stress in rats under diabetic and HFD condition. This current study provides new bioactive starches, with potential applications in the food and non-food industries.
authors: Department of Food Science and Technology, Pondicherry University, Puducherry 605014, India; School of Life Sciences and Biotechnology, Korea University, Seoul 136701, Republic of Korea. Electronic address: koteswarreddychagam@gmail.com.
authors: Chagam Koteswara
authors: CK
authors: Reddy
authors: Department of Food Science and Technology, Pondicherry University, Puducherry 605014, India.
authors: M
authors: M
authors: Suriya
authors: Department of Food Science and Technology, Pondicherry University, Puducherry 605014, India.
authors: P V
authors: PV
authors: Vidya
authors: Department of Food Science and Technology, Pondicherry University, Puducherry 605014, India. Electronic address: shprieya@gmail.com.
authors: Sundaramoorthy
authors: S
authors: Haripriya
mesh_terms: D000818:Animals; D001786:Blood Glucose; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D006003:Glycogen / Q000378:metabolism; D007004:Hypoglycemic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000960:Hypolipidemic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D028521:Musa / Q000737:chemistry*; D018384:Oxidative Stress; D017207:Rats, Sprague-Dawley; D012995:Solubility; D013213:Starch / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D000960:Hypolipidemic Agents; D013213:Starch; D006003:Glycogen
keywords: Amylose; Banana; Diabetes; Modification; Pullulanase; Resistant starch