title: Epidemiology of Polymyalgia Rheumatica 2000-2014 and Examination of Incidence and Survival Trends Over 45 Years: A Population-Based Study.
abstract: To determine time trends in the incidence and survival of polymyalgia rheumatica (PMR) over a 15-year period in Olmsted County, Minnesota, and to examine trends in incidence of PMR in the population by comparing this time period to a previous incidence cohort from the same population base.
  
  
  
  All cases of incident PMR among Olmsted County, Minnesota residents in 2000-2014 were identified to extend the previous 1970-1999 cohort. Detailed review of all individual medical records was performed. Incidence rates were age- and sex-adjusted to the US white 2010 population. Survival rates were compared with the expected rates in the population of Minnesota.
  
  
  
  There were 377 incident cases of PMR during the 15-year study period. Of these, 64% were female and the mean age at incidence was 74.1 years. The overall age- and sex-adjusted annual incidence of PMR was 63.9 (95% confidence interval [95% CI] 57.4-70.4) per 100,000 population ages ≥50 years. Incidence rates increased with age in both sexes, but incidence fell after age 80 years. There was a slight increase in incidence of PMR in the recent time period compared to 1970-1999 (P = 0.063). Mortality among individuals with PMR was not significantly worse than that expected in the general population (standardized mortality ratio 0.70 [95% CI 0.57-0.85]).
  
  
  
  The incidence of PMR has increased slightly in the past 15 years compared to previous decades. Survivorship in patients with PMR is not worse than in the general population.
authors: Mayo Clinic College of Medicine, Rochester, Minnesota.
authors: Shafay
authors: S
authors: Raheel
authors: Mayo Clinic College of Medicine, Rochester, Minnesota.
authors: Izzat
authors: I
authors: Shbeeb
authors: Mayo Clinic College of Medicine, Rochester, Minnesota.
authors: Cynthia S
authors: CS
authors: Crowson
authors: Mayo Clinic College of Medicine, Rochester, Minnesota.
authors: Eric L
authors: EL
authors: Matteson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008910:Minnesota / Q000453:epidemiology; D011111:Polymyalgia Rheumatica / Q000175:diagnosis* / Q000453:epidemiology* / Q000401:mortality; D011159:Population Surveillance / Q000379:methods; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends; D013997:Time Factors