title: Rare case of T-cell lymphoma presenting as acute myelopathy.
abstract: Acute myelopathy is a rare presentation of systemic T-cell lymphoma. We present the case of a man aged 68 years with a diffuse erythematous maculopapular rash, followed by lower extremity paresthesias and progressive lower extremity weakness. Spinal MRI showed longitudinally extensive T2 hyperintensity with diffuse contrast enhancement. An atypical clonal T-lymphocyte population was identified in cerebrospinal fluid, peripheral blood and bone marrow aspirate, indicating a malignant T-cell lymphoproliferative disorder. The patient was treated with intrathecal and systemic chemotherapy. Unfortunately, he was not responsive to chemotherapy.
authors: Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
authors: Verena Clarissa
authors: VC
authors: Samara
authors: Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
authors: Adam
authors: A
authors: de Havenon
mesh_terms: D000208:Acute Disease; D000368:Aged; D003287:Contrast Media; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D016399:Lymphoma, T-Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000209:etiology*
chemical_list: D003287:Contrast Media