title: Bloodstream Infection Due to CTX-M-15 and TEM-1 Extended-Spectrum β-Lactamase-Producing Salmonella enterica serovar Virchow ST16.
abstract: A 57-year-old man presented with high fever and diarrhea. A blood culture revealed the presence of a Group C nontyphoidal Salmonella (NTS) isolate. On Salmonella serotyping, the isolate was identified as Salmonella enterica serovar Virchow. Its sequence type was determined to be ST16 by sequence analysis of 7 different housekeeping genes. The blaCTX-Mgroup 1 and blaTEMgenes were amplified using multiplex PCR assay for detecting extended-spectrum β-lactamases (ESBL) genes. Sequences of both amplicons were respectively identical to CTX-M-15- and TEM-1-encoding genes. Since NTS is a cause of foodborne illness outbreaks in communities and an important cause of community-acquired bloodstream infection, clinicians should consider ESBL- or AmpC-producing NTS species in the differential diagnosis.
authors: Department of Internal Medicine, Chonbuk National University.|Research Institute of Clinical Medicine, Chonbuk National University.|Biomedical Research Institute of Chonbuk National University Hospital.
authors: Jeong-Hwan
authors: JH
authors: Hwang
authors: Biosafety Reference Center and College of Veterinary Medicine, Chonbuk National University.
authors: Gee-Wook
authors: GW
authors: Shin
authors: Department of Internal Medicine, Chonbuk National University.
authors: Joo-Hee
authors: JH
authors: Hwang
authors: Department of Internal Medicine, Chonbuk National University.|Research Institute of Clinical Medicine, Chonbuk National University.|Biomedical Research Institute of Chonbuk National University Hospital.
authors: Chang-Seop
authors: CS
authors: Lee
mesh_terms: D016470:Bacteremia / Q000382:microbiology*; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D060885:Multiplex Polymerase Chain Reaction; D012480:Salmonella Infections / Q000382:microbiology*; D019779:Salmonella enterica / Q000145:classification / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D065288:Serogroup; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases; C034413:beta-lactamase TEM-1
keywords: CTX-M-15; Salmonella enterica serovar Virchow; TEM-1