title: Visual detection of single-nucleotide polymorphisms and DNA methyltransferase based on cation-exchange of CuS nanoparticles and click chemistry of functionalized gold nanoparticles.
abstract: A novel biosensor was developed based on the cation-exchange of CuS nanoparticles (NPs) and Cu(i)-based click chemistry of functionalized gold nanoparticles (AuNPs). As a proof-of-principle, novel applications of this method as a versatile biosensor for single-nucleotide polymorphisms (SNPs) and DNA methyltransferase (MTase) were presented.
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
authors: X R
authors: XR
authors: Zhang
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
authors: Y
authors: http://orcid.org/0000-0002-1006-9728
authors: Y
authors: Zhang
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
authors: F T
authors: FT
authors: Chen
authors: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
authors: Y
authors: Y
authors: Li
authors: Shandong Province Key Laboratory of Detection Technology for Tumor Makers, College of Chemistry and Chemical Engineering, Linyi University, Linyi 276000, P. R. China. shushzhang@126.com.
authors: S S
authors: SS
authors: Zhang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002151:Calorimetry / Q000379:methods*; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry*; D015254:DNA Modification Methylases / Q000378:metabolism*; D006046:Gold / Q000737:chemistry*; D007474:Ion Exchange; D053768:Metal Nanoparticles / Q000737:chemistry*; D020641:Polymorphism, Single Nucleotide
chemical_list: D006046:Gold; D003300:Copper; D015254:DNA Modification Methylases; C017846:cupric sulfide