title: The Effect of Mineral Trioxide Aggregate Mixed with Chlorhexidine as Direct Pulp Capping Agent in Dogs Teeth: A Histologic Study.
abstract: BACKGROUND
  The aim of the present investigation was to compare the efficacy of mineral trioxide aggregate (MTA) and 0.2% chlorhexidine (CHX) mixture to pure MTA, as a pulp capping material.
  
  
  METHODS
  The pulp of 24 lateral incisors and canines from four dogs were exposed and capped either with MTA or MTA+0.2% CHX. After 2 months the animals were sacrificed and the teeth were prepared for histological evaluation in terms of calcified bridge formation, the degree of inflammation and presence of necrosis. The Fisher's exact test was used for data analysis.
  
  
  RESULTS
  The results showed that formation of complete calcified bridge in MTA specimens was significantly more than MTA+CHX (P<0.05). No significant difference was found in the degree of inflammation and necrosis between MTA and MTA+CHX groups (P>0.05).
  
  
  CONCLUSIONS
  Mixing MTA with CHX as pulp capping agent had a significant negative impact on formation of calcified bridge on directly capped dog's teeth.
authors: Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman, Iran.
authors: Hamed
authors: H
authors: Manochehrifar
authors: Oral and Dental Diseases Research Center, Dental School, Kerman University of Medical Sciences, Kerman, Iran.
authors: Masoud
authors: M
authors: Parirokh
authors: Oral and Dental Diseases Research Center, Dental School, Kerman University of Medical Sciences, Kerman, Iran.
authors: Sina
authors: S
authors: Kakooei
authors: Department of Clinical Sciences, Veterinary Medicine School, Shahid Bahonar University of Kerman, Iran.
authors: Mohammad Mehdi
authors: MM
authors: Oloomi
authors: Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Saeed
authors: S
authors: Asgary
authors: Dental Research Center, Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran , Iran.
authors: Mohammad Jafar
authors: MJ
authors: Eghbal
authors: Endodontic Department, Shahid Beheshti Dental School, Tehran, Iran.
authors: Fatemeh
authors: F
authors: Mashhadi Abbas
keywords: Chlorhexidine; Mineral Trioxide Aggregate; Pulp Capping; Vital Pulp Therapy