title: The impact of resection method and patient factors on quality of life among stage IA non-small cell lung cancer surgical patients.
abstract: OBJECTIVE
  Given the increased number of treatment options for stage IA lung cancer patients, there is a growing body of literature that focuses on comparing each option's relative impact on quality of life (QoL). The current study seeks to further understand the differences in these patients' QoL according to surgical approach.
  
  
  METHODS
  Screening-diagnosed first primary pathologic stage IA non-small-cell lung cancer surgical patients from the I-ELCAP cohort who answered a baseline and 1-year follow-up QoL questionnaire (SF-12) were included in the analysis. Thoracotomy patients (N = 85) were compared with VATS patients (N = 15) using paired t-tests and analysis of variance tests.
  
  
  RESULTS
  Multivariate analyses indicated no differences in QoL change between the two groups from pre- to post-surgery. Physical and emotional role functioning significantly improved among VATS patients and worsened among thoracotomy patients. Among thoracotomy patients, a significant decrease in post-surgical physical QoL was observed only in those who underwent lobectomy (-3.3; 95% CI: -5.1,-1.5), not limited resection.
  
  
  CONCLUSIONS
  Although the sample size is small, preliminary findings underscore that changes in overall QoL are similar in VATS and thoracotomy stage IA lung cancer patients. Extension of the resection may be a more relevant factor on QoL post-surgery. J. Surg. Oncol. 2017;115:173-180. © 2016 Wiley Periodicals, Inc.
authors: Department of Occupational Medicine, Epidemiology and Prevention (OMEP), Hofstra Northwell School of Medicine, Great Neck, New York.
authors: Rebecca M
authors: RM
authors: Schwartz
authors: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Rowena
authors: R
authors: Yip
authors: Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Raja M
authors: RM
authors: Flores
authors: Department of Statistics, Stanford University, Stanford, California.
authors: Ingram
authors: I
authors: Olkin
authors: Population Health Science and Policy Department and Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Emanuela
authors: E
authors: Taioli
authors: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York.
authors: Claudia
authors: C
authors: Henschke
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000379:methods*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D020775:Thoracic Surgery, Video-Assisted / Q000379:methods*; D013908:Thoracotomy / Q000379:methods*; D016896:Treatment Outcome
keywords: VATS; limited resection; lobectomy; thoracotomy