title: Sulfonylurea Poisoning in a Healthy Toddler.
abstract: Ingestion of sulfonylureas is life-threatening in toddlers and children due to its strong and prolonged hypoglycemic effect. The authors present a 15-mo-old boy with accidental ingestion of Glipizide who presented with encephalopathy, seizure and severe hypoglycemia. The management included parenteral dextrose and octreotide administration to maintain euglycemia, followed by complete neurological recovery within 24 h. Sulphonylurea intoxication should be considered in previously healthy toddlers and children presenting with hypoglycemia especially if any caregiver is on sulfonylurea drugs.
authors: Department of Pediatrics, Advanced Pediatrics Center, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
authors: Suresh
authors: S
authors: Kumar
authors: Department of Pediatrics, Advanced Pediatrics Center, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
authors: Abhijit
authors: A
authors: Choudhary
authors: Department of Pediatrics, Advanced Pediatrics Center, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
authors: Mahammad
authors: M
authors: Ali
authors: Department of Pediatrics, Advanced Pediatrics Center, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
authors: Vipul
authors: V
authors: Gupta
authors: Department of Pediatrics, Advanced Pediatrics Center, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India. mjshree@hotmail.com.
authors: Jayashree
authors: J
authors: Muralidharan
authors: Department of Pediatrics, Advanced Pediatrics Center, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
authors: Sunit C
authors: SC
authors: Singhi
mesh_terms: D005765:Gastrointestinal Agents / Q000627:therapeutic use; D005913:Glipizide / Q000506:poisoning*; D005947:Glucose / Q000627:therapeutic use; D006801:Humans; D007004:Hypoglycemic Agents / Q000506:poisoning*; D007223:Infant; D008297:Male; D015282:Octreotide / Q000627:therapeutic use
chemical_list: D005765:Gastrointestinal Agents; D007004:Hypoglycemic Agents; D005947:Glucose; D015282:Octreotide; D005913:Glipizide
keywords: Dextrose; Hypoglycemia; Octreotide; Sulfonylurea