title: New lignan glycosides from Justicia procumbens.
abstract: Four new lignan glycosides (1-4), named procumbenosides I, K, L, and M, together with cleistanthin B (5) reported for the first time in the genus Justicia, and 5 other known arylnaphthalene lignan glycosides (6-10) were isolated from the whole plant of Justicia procumbens. The structures of the new compounds were elucidated by extensive one-dimensional (1D) and two-dimensional (2D) NMR experiments and mass spectrometry. Procumbenoside M (4) was a rare sesquilignan glycoside never previously reported in the species of Justicia. The paper also provided insight into the conformational equilibria existing in the lignan glycosides of the plant.
authors: a Department of Medicinal Chemistry , Beijing Institute of Radiation Medicine , Beijing 100850 , China.|b Disinfection Evaluation Research Center , Beijing Institute of Disease Prevention and Control , Beijing 100071 , China.
authors: Hong
authors: H
authors: Jin
authors: c School of Life Science , Tsinghua University , Beijing 100084 , China.
authors: Shu
authors: S
authors: Yang
authors: a Department of Medicinal Chemistry , Beijing Institute of Radiation Medicine , Beijing 100850 , China.
authors: Jun-Xing
authors: JX
authors: Dong
mesh_terms: D027901:Acanthaceae / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D027902:Justicia / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D006027:Glycosides; D017705:Lignans
keywords: Acanthaceae; Justicia procumbens; conformational equilibria; lignan glycosides; sesquilignan glycoside