title: Reduction hybrid artifacts of EMG-EOG in electroencephalography evoked by prefrontal transcranial magnetic stimulation.
abstract: When prefrontal-transcranial magnetic stimulation (p-TMS) performed, it may evoke hybrid artifact mixed with muscle activity and blink activity in EEG recordings. Reducing this kind of hybrid artifact challenges the traditional preprocessing methods. We aim to explore method for the p-TMS evoked hybrid artifact removal.
  
  
  
  We propose a novel method used as independent component analysis (ICA) post processing to reduce the p-TMS evoked hybrid artifact. Ensemble empirical mode decomposition (EEMD) was used to decompose signal into multi-components, then the components were separated with artifact reduced by blind source separation (BSS) method. Three standard BSS methods, ICA, independent vector analysis, and canonical correlation analysis (CCA) were tested.
  
  
  
  Synthetic results showed that EEMD-CCA outperformed others as ICA post processing step in hybrid artifacts reduction. Its superiority was clearer when signal to noise ratio (SNR) was lower. In application to real experiment, SNR can be significantly increased and the p-TMS evoked potential could be recovered from hybrid artifact contaminated signal. Our proposed method can effectively reduce the p-TMS evoked hybrid artifacts.
  
  
  
  Our proposed method may facilitate future prefrontal TMS-EEG researches.
authors: Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, People's Republic of China.
authors: Yang
authors: Y
authors: Bai
authors: Xiaohong
authors: X
authors: Wan
authors: Ke
authors: K
authors: Zeng
authors: Yinmei
authors: Y
authors: Ni
authors: Lirong
authors: L
authors: Qiu
authors: Xiaoli
authors: X
authors: Li
mesh_terms: D000465:Algorithms; D016477:Artifacts; D003198:Computer Simulation; D004569:Electroencephalography / Q000379:methods* / Q000706:statistics & numerical data; D004576:Electromyography / Q000379:methods* / Q000706:statistics & numerical data; D004585:Electrooculography / Q000379:methods* / Q000706:statistics & numerical data; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D017397:Prefrontal Cortex / Q000502:physiology*; D025341:Principal Component Analysis; D015203:Reproducibility of Results; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio; D050781:Transcranial Magnetic Stimulation / Q000379:methods*; D055815:Young Adult