title: A coacervative extraction based on single-chain and double-chain cationic surfactants.
abstract: A coacervative extraction (CAE) with the common cationic surfactants dodecyltrimethylammonium bromide (DTAB) and didodecyldimethylammonium bromide (DDAB) was firstly developed. Notable characteristics of the CAE was the use of low concentration of salt (0.1molL-1NaBr) at ambient temperature and without the requirement of organic solvent. The CAE was based on phase separation due to the neutralization of the surface charge of the micelle by electrostatic interaction with the predominant common counter ion (bromide). The coacervative phase was subjected to an optimized micellar liquid chromatography with UV (MLC-UV) method without any treatments. The method was applied to the determination of penicillins including amoxicillin, ampicillin, penicillin-G, oxacillin, and cloxacillin in milk samples. Method detection limits (MDLs) from standard were 0.5-2ngmL-1, and 40-80-fold analyte enrichment were obtained. The CAE-MLC-UV has shown to be of high potential for the analysis of five penicillins in milk with recoveries >90%.
authors: Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
authors: Chunyapuk
authors: C
authors: Kukusamude
authors: Australian Centre for Research on Separation Science (ACROSS), School of Physical Sciences-Chemistry, University of Tasmania, Hobart 7001, Australia.
authors: Joselito P
authors: JP
authors: Quirino
authors: Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: supalax@kku.ac.th.
authors: Supalax
authors: S
authors: Srijaranai
mesh_terms: D000818:Animals; D001965:Bromides / Q000737:chemistry; D002853:Chromatography, Liquid; D057230:Limit of Detection; D008823:Micelles; D008892:Milk / Q000737:chemistry; D010406:Penicillins / Q000032:analysis; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D012997:Solvents; D055672:Static Electricity; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D001965:Bromides; D008823:Micelles; D010406:Penicillins; D000644:Quaternary Ammonium Compounds; D012997:Solvents; D013501:Surface-Active Agents; C046112:didodecyldimethylammonium; C022806:dodecyltrimethylammonium
keywords: Coacervative extraction; Micellar liquid chromatography; Milk; Penicillins