title: Three-dimensional phase contrast magnetic resonance imaging validated to assess pulmonary artery flow in patients with chronic thromboembolic pulmonary hypertension.
abstract: In this study, three-dimensional phase contrast magnetic resonance imaging (3D-PC MRI), a novel technique, was validated to assess pulmonary artery (PA) flow in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The MR data of PAs from 3D-PC and two-dimensional PC (2D-PC) from before and after treatment for 3 patients with CTEPH were retrospectively analyzed. Additionally, 3D- and 2D-PC MR scans of PA were performed in 5 healthy volunteers. Correlation of stroke volumes (SVs) obtained by 3D-PC and 2D-PC was analyzed using Pearson's correlation coefficients. There was an excellent correlation in the SV of main PA, left PA and right PA between 3D-PC and 2D-PC (main PA: r = 0.91, p < 0.01, left PA: r = 0.72, p < 0.01 and right PA: r = 0.77, p < 0.01). In conclusion, 3D-PC MRI was able to accurately quantify the PA flow in patients with CTEPH.
authors: Department of Radiological Technology, Faculty of Fukuoka Medical Technology, Teikyo University, 6-22 Misaki-machi, Omuta, Fukuoka, Japan. kawakubo@fmt.teikyo-u.ac.jp.
authors: Masateru
authors: M
authors: Kawakubo
authors: Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.|Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors: Hiroshi
authors: H
authors: Akamine
authors: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors: Yuzo
authors: Y
authors: Yamasaki
authors: Philips Electronics Japan, Ltd, Tokyo, Japan.
authors: Atsushi
authors: A
authors: Takemura
authors: Department of Advanced Cardiovascular Regulation and Therapeutics, Center for Disruptive Cardiovascular Medicine, Kyushu University, Fukuoka, Japan.
authors: Kohtaro
authors: K
authors: Abe
authors: Department of Cardiovascular Medicine, Kyushu University Hospital, Fukuoka, Japan.
authors: Kazuya
authors: K
authors: Hosokawa
authors: Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors: Junji
authors: J
authors: Morishita
authors: Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
authors: Michinobu
authors: M
authors: Nagao
mesh_terms: D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000000981:diagnostic imaging* / Q000503:physiopathology; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011655:Pulmonary Embolism / Q000150:complications*; D012189:Retrospective Studies
keywords: 3-dimensional phase contrast MRI; Chronic thromboembolic pulmonary hypertension; Magnetic resonance imaging; Pulmonary artery flow