title: Transvection Arising from Transgene Interactions in Zebrafish.
abstract: There has been a rapid expansion in use of transgenic technologies in zebrafish. We report a novel example of transinteractions of genetic elements, or transvection. This interaction led to a novel expression pattern and illustrates a precautionary example regarding use of transgenes in zebrafish.
authors: Department of Pediatrics, Department of Neurobiology and Anatomy, University of Utah School of Medicine , Salt Lake City, Utah.
authors: Matthew D
authors: MD
authors: Keefe
authors: Department of Pediatrics, Department of Neurobiology and Anatomy, University of Utah School of Medicine , Salt Lake City, Utah.
authors: Joshua L
authors: JL
authors: Bonkowsky
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D004843:Epistasis, Genetic; D005786:Gene Expression Regulation; D049452:Green Fluorescent Proteins / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D024661:Potassium Channels, Inwardly Rectifying / Q000235:genetics / Q000378:metabolism; D011401:Promoter Regions, Genetic; D012045:Regulatory Sequences, Nucleic Acid; D019076:Transgenes; D015027:Zebrafish / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism
chemical_list: C489457:KCNJ2 protein, human; D024661:Potassium Channels, Inwardly Rectifying; D049452:Green Fluorescent Proteins
keywords: Gal4; UAS; transgenic; transvection; zebrafish