title: De novo assembly of plant body plan: a step ahead of Deadpool.
abstract: While in the movie Deadpool it is possible for a human to recreate an arm from scratch, in reality plants can even surpass that. Not only can they regenerate lost parts, but also the whole plant body can be reborn from a few existing cells. Despite the decades old realization that plant cells possess the ability to regenerate a complete shoot and root system, it is only now that the underlying mechanisms are being unraveled. De novo plant regeneration involves the initiation of regenerative mass, acquisition of the pluripotent state, reconstitution of stem cells and assembly of regulatory interactions. Recent studies have furthered our understanding on the making of a complete plant system in the absence of embryonic positional cues. We review the recent studies probing the molecular mechanisms of de novo plant regeneration in response to external inductive cues and our current knowledge of direct reprogramming of root to shoot and vice versa. We further discuss how de novo regeneration can be exploited to meet the demands of green culture industries and to serve as a general model to address the fundamental questions of regeneration across the plant kingdom.
authors: School of Biology Indian Institute of Science Education and Research Thiruvananthapuram Kerala 695016 India.
authors: Abdul
authors: A
authors: Kareem
authors: School of Biology Indian Institute of Science Education and Research Thiruvananthapuram Kerala 695016 India.
authors: Dhanya
authors: D
authors: Radhakrishnan
authors: School of Biology Indian Institute of Science Education and Research Thiruvananthapuram Kerala 695016 India.
authors: Yash
authors: Y
authors: Sondhi
authors: School of Biology Indian Institute of Science Education and Research Thiruvananthapuram Kerala 695016 India.
authors: Mohammed
authors: M
authors: Aiyaz
authors: School of Biology Indian Institute of Science Education and Research Thiruvananthapuram Kerala 695016 India.
authors: Merin V
authors: MV
authors: Roy
authors: Department of Applied Biological Science Faculty of Science and Technology Tokyo University of Science 2641 Yamazaki Noda Chiba 278-8510 Japan.
authors: Kaoru
authors: K
authors: Sugimoto
authors: School of Biology Indian Institute of Science Education and Research Thiruvananthapuram Kerala 695016 India.
authors: Kalika
authors: K
authors: Prasad
keywords: auxin; callus; cytokinin; de novo organogenesis; pluripotency; regeneration; stem cells; transdifferentiation