title: Robotic Intracorporeal Padua Ileal Bladder: Surgical Technique, Perioperative, Oncologic and Functional Outcomes.
abstract: Robot-assisted radical cystectomy (RARC) with intracorporeal neobladder reconstruction is a challenging procedure. The need for surgical skills and the long operative times have led to concern about its reproducibility.
  
  
  
  To illustrate our technique for RARC and totally intracorporeal orthotopic Padua ileal bladder.
  
  
  
  From August 2012 to February 2014, 45 patients underwent this technique at a single tertiary referral centre.
  
  
  
  RARC, extended pelvic lymph node dissection, and intracorporeal partly stapled neobladder. Surgical steps are demonstrated in the accompanying video.
  
  
  
  Demographics, clinical, and pathological data were collected. Perioperative, 2-yr oncologic and 2-yr functional outcomes were reported.
  
  
  
  Intraoperative transfusion or conversion to open surgery was not necessary in any case and intracorporeal neobladder was successfully performed in all 45 patients. Median operative time was 305min (interquartile range [IQR]: 282-345). Median estimated blood loss was 210ml (IQR: 50-250). Median hospital stay was 9 d (IQR: 7-12). The overall incidence of perioperative, 30-d and 180-d complications were 44.4%, 57.8%, and 77.8%, respectively, while severe complications occurred in17.8%, 17.8%, and 35.5%, respectively. Two-yr daytime and night-time continence rates were 73.3% and 55.5%, respectively. Two-yr disease free survival, cancer specific survival, and overall survival rates were 72.5%, 82.3%, and 82.4%, respectively. The small sample size and high caseload of the centre might affect the reproducibility of these results.
  
  
  
  Our experience supports the feasibility of totally intracorporeal neobladder following RARC. Operative times and perioperative complication rates are likely to be reduced with increasing experience.
  
  
  
  We report the outcomes of our first 45 consecutive patients who underwent robot-assisted radical cystectomy with intracorporeal neobladders. Perioperative, oncologic, and functional outcomes support this technique as a feasible and safe surgical option in tertiary referral centres.
authors: Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy. Electronic address: puldet@gmail.com.
authors: Giuseppe
authors: G
authors: Simone
authors: Department of Urology, Campus Biomedico University, Rome, Italy.
authors: Rocco
authors: R
authors: Papalia
authors: Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.
authors: Leonardo
authors: L
authors: Misuraca
authors: Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.
authors: Gabriele
authors: G
authors: Tuderti
authors: Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.
authors: Francesco
authors: F
authors: Minisola
authors: Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.
authors: Mariaconsiglia
authors: M
authors: Ferriero
authors: Department of Radiology, "Regina Elena" National Cancer Institute, Rome, Italy.
authors: Giulio
authors: G
authors: Vallati
authors: Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.
authors: Salvatore
authors: S
authors: Guaglianone
authors: Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.
authors: Michele
authors: M
authors: Gallucci
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical; D002295:Carcinoma, Transitional Cell / Q000601:surgery*; D015653:Cystectomy / Q000009:adverse effects / Q000379:methods*; D018572:Disease-Free Survival; D053207:Diurnal Enuresis / Q000209:etiology; D005260:Female; D006801:Humans; D007082:Ileum / Q000637:transplantation*; D007902:Length of Stay; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D053206:Nocturnal Enuresis / Q000209:etiology; D061646:Operative Time; D011183:Postoperative Complications / Q000209:etiology; D065287:Robotic Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D015996:Survival Rate; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014549:Urinary Incontinence / Q000209:etiology; D016476:Urinary Reservoirs, Continent / Q000009:adverse effects / Q000502:physiology
keywords: Bladder cancer; Intracorporeal urinary diversion; Orthotopic neobladder; Padua ileal bladder; Radical cystectomy; Robotic intracorporeal neobladder; Robotic surgery