title: Cervical Decompression Surgery for Cervical Spondylotic Myelopathy and Concomitant Hypertension: A Multicenter Prospective Cohort Study.
abstract: METHODS
  We performed decompression surgery or conservative treatments on 135 cervical spondylotic myelopathy (CSM) patients with concomitant hypertension and did follow-up assessments up to 1 year to examine the change of blood pressure, spinal cord function, and cervical pain.
  
  
  OBJECTIVE
  The aim of this study was to determine whether concomitant hypertension is relieved after decompression surgery, and whether it is related to the improvement of spinal cord function or cervical pain.
  
  
  BACKGROUND
  In clinical practice, we often found that some patients with CSM have concomitant hypertension. Interestingly, after CSM was treated successfully by decompression surgery, some patients' high blood pressure returned to normal range even without oral medications.
  
  
  METHODS
  We enrolled 135 CSM patients with hypertension, 103 of whom received decompression surgery, and remaining 32 patients accepted conservative treatments. We did follow-up assessments at 3, 6, and 12 months. The primary endpoints were changes of blood pressure, and secondary endpoints were changes of modified Japanese Orthopedic Association (mJOA) score and cervical pain visual analogue scale (VAS). Spearman correlation coefficients were calculated between changes in systolic blood pressure (SBP) and mJOA scores, VAS scores.
  
  
  RESULTS
  In patients with decompression surgery, the significant decrease in both SBP and diastolic blood pressure (DBP) that was seen 3 months and sustained through subsequent visit at 12 months. Paired-samples t test showed that both SBP and DBP were significantly lower than baseline blood pressure at all time points after procedure (P < 0.001). Significant correlation was found between the improvement rates of mJOA score and changes in SBP (r = -0.579, P < 0.001). But the correlation between changes in VAS score and changes in SBP was not significant (r = 0.58, P = 0.571).
  
  
  CONCLUSIONS
  Cervical decompression surgery could reduce concomitant high blood pressure in CSM patients, indicating a significant association between the decrease in blood pressure and the improvement of spinal cord function.
  
  
  METHODS
  2.
authors: Department of Orthopaedics, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.|Department of Orthopeadics, Pingjin Hospital, Logistics College of Armed Police Forces, Tianjin, China.
authors: Liang
authors: L
authors: Yang
authors: Department of Orthopeadics, Changzheng Hospital, Shanghai, China.
authors: Cheng
authors: C
authors: Yang
authors: Department of Spinal Surgery, General Hospital of Armed Police Force, Beijing, China.
authors: Xiaodong
authors: X
authors: Pang
authors: Department of Spinal Surgery, General Hospital of Armed Police Force, Beijing, China.
authors: Duanming
authors: D
authors: Li
authors: Department of Orthopeadics, Changzheng Hospital, Shanghai, China.
authors: Xiongsheng
authors: X
authors: Chen
authors: Department of Orthopeadics, Changzheng Hospital, Shanghai, China.
authors: Jiangang
authors: J
authors: Shi
authors: Department of Orthopeadics, Changzheng Hospital, Shanghai, China.
authors: Xuhui
authors: X
authors: Zhou
authors: Department of Orthopeadics, 304th Hospital, Beijing, China.
authors: Ye
authors: Y
authors: Wu
authors: Department of Orthopeadics, 304th Hospital, Beijing, China.
authors: Xiang
authors: X
authors: Lu
authors: Department of Spinal Surgery, General Hospital of Armed Police Force, Beijing, China.
authors: Hong
authors: H
authors: Yang
authors: Department of Orthopeadics, Changzheng Hospital, Shanghai, China.
authors: Lianshun
authors: L
authors: Jia
authors: Department of Spinal Surgery, General Hospital of Armed Police Force, Beijing, China.
authors: Baogan
authors: B
authors: Peng
mesh_terms: D000368:Aged; D002574:Cervical Vertebrae / Q000601:surgery*; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013118:Spinal Cord Diseases / Q000209:etiology / Q000601:surgery*; D055009:Spondylosis / Q000150:complications / Q000601:surgery*