title: Cleft relapse and oronasal fistula after Furlow palatoplasty in infants with cleft palate: incidence and risk factors.
abstract: This study was performed to investigate the incidence of and risk factors for postoperative cleft relapse and oronasal fistula after Furlow palatoplasty in infants. Sixty-two infants with cleft palate, aged 6-12 months (mean 8.25 months), who underwent cleft repair by Furlow double opposing Z-plasty between March 2012 and August 2014, were enrolled in the study. Risk factors for postoperative cleft relapse and oronasal fistula after Furlow palatoplasty were identified by logistic regression analysis. The incidence rates of cleft relapse at 1 week and oronasal fistula at 3 months after surgery were 24.2% (15/62) and 9.7% (6/62), respectively. Among all of the variables screened, only the width of the cleft was significantly associated with the incidence of postoperative cleft relapse (P=0.001) and oronasal fistula (P=0.011); the incidence rates were positively correlated with the width of the cleft when it exceeded 6.8mm and 7.5mm, respectively. Based on these findings, in order to reduce the incidence of postoperative cleft relapse and oronasal fistula, Furlow repair is not recommended for patients with wide clefts. An appropriate angle between the Z-flap incision and the central axis, use of a bilateral relaxation incision, and postoperative nursing care can help reduce the incidence of postoperative cleft relapse.
authors: Guangzhou Women and Children's Medical Centre, Guangzhou 510623, Guangdong Province, China.
authors: F
authors: F
authors: Li
authors: Guangzhou Women and Children's Medical Centre, Guangzhou 510623, Guangdong Province, China. Electronic address: 18198907570@163.com.
authors: H-T
authors: HT
authors: Wang
authors: Guangzhou Women and Children's Medical Centre, Guangzhou 510623, Guangdong Province, China.
authors: Y-Y
authors: YY
authors: Chen
authors: Guangzhou Women and Children's Medical Centre, Guangzhou 510623, Guangdong Province, China.
authors: W-L
authors: WL
authors: Wu
authors: Guangzhou Women and Children's Medical Centre, Guangzhou 510623, Guangdong Province, China.
authors: J-Y
authors: JY
authors: Liu
authors: Guangzhou Women and Children's Medical Centre, Guangzhou 510623, Guangdong Province, China.
authors: J-S
authors: JS
authors: Hao
authors: Guangzhou Women and Children's Medical Centre, Guangzhou 510623, Guangdong Province, China.
authors: D-Y
authors: DY
authors: Luo
mesh_terms: D002972:Cleft Palate / Q000601:surgery*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D009668:Nose Diseases / Q000209:etiology*; D016155:Oral Fistula / Q000209:etiology*; D011183:Postoperative Complications / Q000209:etiology*; D012008:Recurrence; D012307:Risk Factors; D016896:Treatment Outcome
keywords: cleft palate; cleft relapse; fistula; furlow palatoplasty; infant