title: Ginseng in Dermatology: A Review.
abstract: Ginseng has gained fame as one of the most popular herbs originating from Eastern countries. Among different species which are known as ginseng, Panax ginseng C. A. Mey. (Korean or Asian ginseng) is the most frequently used one. Ginsenosides have been proposed to account for most of the biological activities of ginseng. The widely appreciated health-promoting effect of ginseng pertains to the beneficial effects of this plant against immune, cardiovascular and sexual diseases and cancer. In addition, there are some new aspects of the pharmacological activity of this plant which justify its use in dermatologic diseases. In dermatology, ginseng has been investigated mechanistically for its therapeutic effects in photoaging, wound and injury, skin cancer, dermatitis, hair loss, alopecia and cold hypersensitivity. Here, we reviewed experimental and clinical studies exploring the therapeutic efficacy of ginseng and ginsenosides in the field of dermatology.
authors: Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Sarvenaz
authors: S
authors: Sabouri-Rad
authors: Department of Dermatology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Sara
authors: S
authors: Sabouri-Rad
authors: Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Amirhossein
authors: A
authors: Sahebkar
authors: Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Zahra
authors: Z
authors: Tayarani-Najaran
mesh_terms: D049109:Cell Proliferation / Q000187:drug effects; D003880:Dermatology; D036145:Ginsenosides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D005894:Panax / Q000737:chemistry* / Q000378:metabolism; D012871:Skin Diseases / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology
chemical_list: D036145:Ginsenosides
keywords: Ginseng; cancer; cold hyper sensitivity; dermatitis; dermatology; hair loss; photoaging; wound