title: α Herpes Virus Infections Among Renal Transplant Recipients.
abstract: The α herpes viruses HSV-1, HSV-2, and VZV often reactivate in the setting of immune suppression after solid organ transplantation. Oral or genital mucocutaneous disease is the most common clinical manifestation of HSV disease while VZV manifests as varicella (or chickenpox) or reactivation herpes zoster, characterized by a diffuse rash, or a painful unilateral vesicular eruption in a dermatomal distribution, respectively. The diagnosis of HSV and VZV is primarily based on history and clinical presentation, although diagnostic tests may be necessary for atypical presentations of disease. Treatment usually involves oral or intravenous antiviral therapy, depending on severity of illness.
authors: Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN.
authors: Cybele Lara
authors: CL
authors: Abad
authors: Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN; The William J. Von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN. Electronic address: razonable.raymund@mayo.edu.
authors: Raymund R
authors: RR
authors: Razonable
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002644:Chickenpox / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control; D019433:Chickenpox Vaccine / Q000627:therapeutic use; D046508:Culture Techniques; D019085:Fluorescent Antibody Technique, Direct; D006084:Graft Rejection / Q000517:prevention & control*; D006561:Herpes Simplex / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D006562:Herpes Zoster / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control; D018259:Herpesvirus 1, Human; D018258:Herpesvirus 2, Human; D014645:Herpesvirus 3, Human; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D016133:Polymerase Chain Reaction; D012698:Serologic Tests; D014775:Virus Activation
chemical_list: D000998:Antiviral Agents; D019433:Chickenpox Vaccine; D007166:Immunosuppressive Agents
keywords: infection; kidney transplant; α virus