title: Tailored deep brain stimulation optimization for improved airway protective outcomes in Parkinson's disease.
abstract: There is no consensus regarding the effects of deep brain stimulation (DBS) surgery on swallowing outcomes in Parkinson's disease (PD). No prospective studies have compared airway protective outcomes following DBS to the subthalamic nucleus (STN) versus globus pallidus interna (GPi). A recent retrospective study described swallowing outcomes pre- and post-STN vs. GPi DBS in a cohort of 34 patients with PD. The results revealed that the patients who received GPi DBS maintained their swallowing function post-DBS, while those in the STN group significantly worsened in swallowing safety. As DBS surgery becomes a common management option in PD it is important to understand the impact of DBS on airway protective outcomes; especially given that aspiration pneumonia is the leading cause of death in this population. We present a case report in which optimizing DBS settings with the goal of improving laryngeal function resulted in immediate improvements to swallowing safety.
authors: Center for Movement Disorders and Neurorestoration, University of Florida, 3450 Hull Rd, Gainesville, FL 32607, USA; Laboratory for the Study of Upper Airway Dysfunction, Teachers College, Columbia University, 525 West 120 Street, New York, NY 10027, USA.
authors: Michelle S
authors: MS
authors: Troche
authors: Center for Movement Disorders and Neurorestoration, University of Florida, 3450 Hull Rd, Gainesville, FL 32607, USA; Laboratory for the Study of Upper Airway Dysfunction, Teachers College, Columbia University, 525 West 120 Street, New York, NY 10027, USA.
authors: Alexandra E
authors: AE
authors: Brandimore
authors: Center for Movement Disorders and Neurorestoration, University of Florida, 3450 Hull Rd, Gainesville, FL 32607, USA.
authors: Karen W
authors: KW
authors: Hegland
authors: Center for Movement Disorders and Neurorestoration, University of Florida, 3450 Hull Rd, Gainesville, FL 32607, USA.
authors: Pamela R
authors: PR
authors: Zeilman
authors: Center for Movement Disorders and Neurorestoration, University of Florida, 3450 Hull Rd, Gainesville, FL 32607, USA.
authors: Kelly D
authors: KD
authors: Foote
authors: Center for Movement Disorders and Neurorestoration, University of Florida, 3450 Hull Rd, Gainesville, FL 32607, USA.
authors: Michael S
authors: MS
authors: Okun
keywords: Parkinson's disease; aspiration; deep brain stimulation surgery; dysphagia; laryngoscopy; swallowing