title: [Assessment and intervention thresholds to detect cases at risk of osteoporosis and fragility fractures with FRAX® in a mexican population for the first level of healthcare].
abstract: OBJECTIVE
  To estimate the evaluation and intervention thresholds using FRAX® in Mexican population.
  
  
  METHODS
  Probabilities for a mayor fracture using the Mexican FRAX® version to estimate the evaluation and intervention thresholds using clinical scenarios were obtained in both sexes 40 years and over. Projections for 2020 were done to estimate the number of patients at the intervention level taking the osteoporosis prevalence in Mexicans aged 50 years and over.
  
  
  RESULTS
  The cutoffs for the intervention thresholds were 2.6%-20.0%. Individuals with thresholds above these probabilities are amenable for intervention. The assessment thresholds range from 1.2-3.2% to 12.5-24.4% for 40 to 90 years. According to projections of our population, approximately three million people are susceptible to intervention by 2020.
  
  
  CONCLUSIONS
  The use of FRAX® thresholds of intervention and evaluation developed in this study will be useful in the primary care level for case detection at high risk of fragility fracture.
authors: Unidad de Epidemiología Clínica, Hospital Infantil Federico Gómez, Facultad de Medicina, UNAM, Ciudad de México, México.
authors: Patricia
authors: P
authors: Clark
authors: Laboratorio de Genética, Instituto Nacional de Rehabilitación, Ciudad de México, México.
authors: Esperanza
authors: E
authors: Ramírez-Pérez
authors: Centro de Estudios Económicos y Sociales en Salud, Hospital Infantil Federico Gómez, Ciudad de México, México.
authors: Alfonso
authors: A
authors: Reyes-López
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D015519:Bone Density; D005260:Female; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D015995:Prevalence; D011336:Probability; D012016:Reference Values; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors