title: A new bookmark of the mitotic genome in embryonic stem cells.
abstract: Embryonic stem cells maintain pluripotency through countless mitoses. A recent report shows that the transcription factor Esrrb remains bound to chromatin during mitosis, including at regulatory regions that support pluripotency. Mitotic chromatin occupancy by Esrrb might stabilize the defining transcriptional programmes of embryonic stem cells through cell division.
authors: Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
authors: Chris C-S
authors: CC
authors: Hsiung
authors: Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
authors: Gerd A
authors: GA
authors: Blobel
mesh_terms: D000818:Animals; D002843:Chromatin / Q000378:metabolism*; D053595:Embryonic Stem Cells / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D016678:Genome; D006801:Humans; D008938:Mitosis / Q000235:genetics*; D011485:Protein Binding; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D002843:Chromatin; D014157:Transcription Factors