title: The use of electric, magnetic, and electromagnetic field for directed cell migration and adhesion in regenerative medicine.
abstract: Directed cell migration and adhesion is essential to embryonic development, tissue formation and wound healing. For decades it has been reported that electric field (EF), magnetic field (MF) and electromagnetic field (EMF) can play important roles in determining cell differentiation, migration, adhesion, and evenwound healing. Combinations of these techniques have revealed new and exciting explanations for how cells move and adhere to surfaces; how the migration of multiple cells are coordinated and regulated; how cellsinteract with neighboring cells, and also to changes in their microenvironment. In some cells, speed and direction are voltage dependent. Data suggests that the use of EF, MF and EMF could advance techniques in regenerative medicine, tissue engineering and wound healing. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 33:5-16, 2017.
authors: The Wake Forest Institute for Regenerative Medicine, Wake Forest Center for Integrative Medicine, Medical Center Blvd, Winston-Salem, NC.
authors: Christina L
authors: CL
authors: Ross
mesh_terms: D002448:Cell Adhesion; D002454:Cell Differentiation; D002465:Cell Movement; D058948:Cell Tracking / Q000379:methods*; D004560:Electricity; D004574:Electromagnetic Fields; D006801:Humans; D044968:Regenerative Medicine; D023822:Tissue Engineering / Q000379:methods; D014945:Wound Healing / Q000235:genetics
keywords: cathode and anode; guidance cues; polarization; scaffolds; wound healing