title: Evaluation of the acceptability of a vaccine against herpes zoster in the over 50 years old: an Italian observational study.
abstract: The aim of the study was to evaluate awareness of the varicella zoster virus and the acceptability of the newly available herpes zoster (HZ) vaccine in the over 50 years old general population.
  
  
  
  The research was observational.
  
  
  
  The study was carried out in Ferrara by administering a questionnaire to patients of the Local Health Authority (LHA), general practitioners (GPs) and Public Health Department outpatient clinics.
  
  
  
  The questionnaire was completed by 1001 residents of Ferrara Province.
  
  
  
  Of the respondents, 98% and 95% (57% female) were aware of varicella and HZ, respectively, but 91% were unaware of the HZ vaccine. Nevertheless, 58% declared that they were in favour of vaccination in this regard, and the acceptability of the vaccine was positively affected by: age (p=0.005); knowing someone who had suffered from HZ (p=0.05); being in favour of vaccination in general (p<0.0001); receiving advice to do so from their GP (p<0.0001) and willingness to get vaccinated even on a fee-paying basis (p<0.0001). Indeed, most (73%) respondents were willing to pay to get vaccinated, indicating an ideal cost of €50. Higher education (p=0.04), being in favour of vaccinations in general (p<0.0001) and GP advice (p<0.0001) positively affected this choice. Furthermore, 61% of the participants initially unfavourable (p<0.0001) to this immunisation would change their decision not to vaccinate thanks to their GP's advice.
  
  
  
  This study assessed the level of awareness and the attitudes of the population aged over 50 years, highlighting aspects to be focused on in the promotion of the HZ vaccine.
authors: Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
authors: Nicoletta
authors: N
authors: Valente
authors: Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
authors: Silvia
authors: S
authors: Lupi
authors: Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
authors: Armando
authors: A
authors: Stefanati
authors: Department of Public Health, Ferrara Local Health Authority, Ferrara, Italy.
authors: Marisa
authors: M
authors: Cova
authors: Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
authors: Najada
authors: N
authors: Sulcaj
authors: Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
authors: Lucia
authors: L
authors: Piccinni
authors: Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
authors: Giovanni
authors: G
authors: Gabutti
mesh_terms: D000368:Aged; D004522:Educational Status; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006562:Herpes Zoster / Q000453:epidemiology / Q000517:prevention & control*; D053061:Herpes Zoster Vaccine / Q000627:therapeutic use*; D014645:Herpesvirus 3, Human / Q000276:immunology / Q000472:pathogenicity*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D014611:Vaccination / Q000706:statistics & numerical data*
chemical_list: D053061:Herpes Zoster Vaccine
keywords: Acceptability; Herpes Zoster; Vaccine