title: Leukemic infiltration presenting as myocardial hypertrophy after complete remission of acute myeloid leukemia.
abstract: Here, we report a rare case of isolated leukemic infiltrate of the myocardium (extramedullary involvement) presenting as restrictive cardiomyopathy in a patient in complete remission of acute myeloid leukemia. It was evaluated with multimodality imaging studies (echocardiography and cardiac MRI) and further confirmed by pathology. The present case highlights the importance of maintaining a high degree of clinical suspicion when evaluating patients with progressive ventricular hypertrophy of unknown cause, including recognition of the potential involvement by recurrent hematologic malignancy.
authors: Cardiovascular Center, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors: Mi-Hyang
authors: http://orcid.org/0000-0003-0224-5178
authors: MH
authors: Jung
authors: Department of Pathology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors: Youn-Ho
authors: YH
authors: Lee
authors: Department of Pathology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors: Kyo-Young
authors: KY
authors: Lee
authors: Cardiovascular Center, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors: Hae Ok
authors: HO
authors: Jung
authors: Cardiovascular Center, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors: Ho-Joong
authors: HJ
authors: Youn
mesh_terms: D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis* / Q000209:etiology; D004452:Echocardiography / Q000379:methods*; D006801:Humans; D006984:Hypertrophy; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D017254:Leukemic Infiltration / Q000175:diagnosis*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D012074:Remission Induction
keywords: echocardiography; left ventricular hypertrophy; leukemia; restrictive cardiomyopathy