title: Duplications of an iron-sulphur tripeptide leads to the formation of a protoferredoxin.
abstract: Based on UV-Vis, NMR, and EPR spectroscopies and DFT and molecular dynamics calculations, a model prebiotic [2Fe-2S] tripeptide was shown to accept and donate electrons. Duplications of the tripeptide sequence led to a protoferredoxin with increased stability. Duplications of primitive peptides may have contributed to the formation of contemporary ferredoxins.
authors: CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, Italy. mansy@science.unitn.it.
authors: Simone
authors: S
authors: Scintilla
authors: CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, Italy. mansy@science.unitn.it.
authors: Claudia
authors: C
authors: Bonfio
authors: CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, Italy. mansy@science.unitn.it.
authors: Luca
authors: L
authors: Belmonte
authors: CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, Italy. mansy@science.unitn.it.
authors: Michele
authors: M
authors: Forlin
authors: CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, Italy. mansy@science.unitn.it.
authors: Daniele
authors: D
authors: Rossetto
authors: Department of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Ave, Columbus, OH 43210, USA.
authors: Jingwei
authors: J
authors: Li
authors: Department of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Ave, Columbus, OH 43210, USA.
authors: James A
authors: JA
authors: Cowan
authors: Department of Chemistry, University of "Bari A. Moro", Via E. Orabona 4, 70125 Bari, Italy.
authors: Angela
authors: A
authors: Galliani
authors: Department of Chemistry, University of "Bari A. Moro", Via E. Orabona 4, 70125 Bari, Italy.
authors: Fabio
authors: F
authors: Arnesano
authors: Department of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
authors: Michael
authors: M
authors: Assfalg
authors: CIBIO, University of Trento, Via Sommarive 9, 38123 Povo, Italy. mansy@science.unitn.it.
authors: Sheref S
authors: http://orcid.org/0000-0003-2382-198X
authors: SS
authors: Mansy