title: Resistin may be an independent predictor of subclinical atherosclerosis formale smokers.
abstract: To investigate whether resistin is associated with early atherosclerosis in male smokers. The present study consecutively enrolled 50 male smokers. Their serum resistin contents were detected with enzyme linked immunosorbent assay (ELISA), and subclinical atherosclerosis indices, including carotid inner middle thickness (IMT) and arterial elasticity indices (C1 and C2), were measured. The association between serum resistin levels and IMT, C1 and C2 were respectively evaluated with the Pearson's correlation coefficient method. The results showed that the serum resistin level had a positive association with IMT (r = 0.307, p = .030), but were both inversely associated with C1 (r = -0.440, p = .001) and C2 (r = -0.381, p = .006). These associations remained significant even after adjustment for cardiovascular confounders. In conclusion, serum resistin concentration was independently associated with early atherosclerosis in male smokers.
authors: a Institute of Endemic Disease, Xi'an Jiao Tong University College of Medicine , Xi'an City , Shaanxi Province , China.
authors: Ying
authors: Y
authors: He
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Xiao-Jun
authors: XJ
authors: Bai
authors: c Department of Internal Medicine , The Second Affiliated Hospital of Xi'an Medical the College , Xi'an City , Shaanxi Province , China.
authors: Fen-Xia
authors: FX
authors: Li
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Li-Hong
authors: LH
authors: Fan
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Jie
authors: J
authors: Ren
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Qi
authors: Q
authors: Liang
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Hong-Bing
authors: HB
authors: Li
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Ling
authors: L
authors: Bai
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Hong-Yan
authors: HY
authors: Tian
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Fen-Ling
authors: FL
authors: Fan
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Gang
authors: G
authors: Tian
authors: b Department of Cardiology , The First Affiliated Hospital of Xi'an Jiao Tong University , Shaanxi Province , China.
authors: Ai-Qun
authors: AQ
authors: Ma
authors: a Institute of Endemic Disease, Xi'an Jiao Tong University College of Medicine , Xi'an City , Shaanxi Province , China.
authors: Jinghong
authors: J
authors: Chen
mesh_terms: D001158:Arteries / Q000502:physiology; D050197:Atherosclerosis / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D059168:Carotid Intima-Media Thickness; D004548:Elasticity; D006801:Humans; D008297:Male; D008875:Middle Aged; D052243:Resistin / Q000097:blood*; D012907:Smoking / Q000009:adverse effects*
chemical_list: C499624:RETN protein, human; D052243:Resistin
keywords: Resistin; arterial elasticity; atherosclerosis; intima media thickness; smoking