title: Palladium-Catalyzed Multi-Component Reactions of N-Tosylhydrazones, 2-Iodoanilines and CO2towards 4-Aryl-2-Quinolinones.
abstract: A palladium-catalyzed three-component reaction between N-tosylhydrazones, 2-iodoanilines and atmospheric pressure CO2was developed whereby a tandem carbene migration insertion/lactamization strategy afforded 4-aryl-2-quinolinones in moderate to good yields. Notably, a wide range of functional groups were tolerated in this procedure. This protocol features the simultaneous formation of four novel bonds; two C-C, one C=C and one C-N (amide), representing an efficient methodology for incorporation of CO2into heterocycles.
authors: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, and Jiangsu Province Key Laboratory of Fine Petrochemical Engineering, Changzhou University, Gehu Road 1, Changzhou, 213164, P. R. China.
authors: Song
authors: S
authors: Sun
authors: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, and Jiangsu Province Key Laboratory of Fine Petrochemical Engineering, Changzhou University, Gehu Road 1, Changzhou, 213164, P. R. China.
authors: Wei-Ming
authors: WM
authors: Hu
authors: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, and Jiangsu Province Key Laboratory of Fine Petrochemical Engineering, Changzhou University, Gehu Road 1, Changzhou, 213164, P. R. China.
authors: Ning
authors: N
authors: Gu
authors: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, and Jiangsu Province Key Laboratory of Fine Petrochemical Engineering, Changzhou University, Gehu Road 1, Changzhou, 213164, P. R. China.
authors: Jiang
authors: J
authors: Cheng
keywords: 4-aryl-2-quinolinone; N-tosylhydrazone; carbon dioxide fixation; heterocycles; multi-component reaction