title: 18F-Florbetaben: A New Tool for Amyloidosis Staging?
abstract: We report the case of a 73-year-old man with a documented (renal biopsy) light-chain amyloidosis (AL) imaged with F-AV-1 (F-florbetaben) compared with a volunteer. A cardiac amyloidosis was suspected. As it was an AL and not a transthyretin amyloidosis, F-FDG and F-florbetaben PET/CT were preferred to bone scan. F-FDG scintigraphy showed a focal cardiac hypermetabolism. In addition of the heart, F-florbetaben scintigraphy showed an intense spleen and thyroid pathologic uptake and a moderate salivary gland and kidney uptake. F-florbetaben PET/CT appears to be useful for staging systemic amyloidosis.
authors: From the *Nuclear Medicine Department, and †Nephrology Department, University Hospital, Nîmes; and ‡INSERM U1194, IRCM, Montpellier, France.
authors: Emmanuel
authors: E
authors: D'Estanque
authors: Benjamin
authors: B
authors: Chambert
authors: Olivier
authors: O
authors: Moranne
authors: Pierre Olivier
authors: PO
authors: Kotzki
authors: Vincent
authors: V
authors: Boudousq
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging* / Q000473:pathology; D000814:Aniline Compounds; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals; D013154:Spleen / Q000000981:diagnostic imaging; D013267:Stilbenes; D013961:Thyroid Gland / Q000000981:diagnostic imaging
chemical_list: D000814:Aniline Compounds; D019275:Radiopharmaceuticals; D013267:Stilbenes; C527756:4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbene