title: [Fundus autofluorescence. Has it a place in the management of diabetic macular edema?]
abstract: OBJECTIVE
  Analyze the characteristics of fundus autofluorescence of diabetic macular edema and study the association between these characteristics and visual function.
  
  
  METHODS
  Our study included 18 patients (28 eyes) with clinically significant diabetic macular edema. All patients had a complete eye examination with a fundus autofluorescence imaging and optical coherence tomography. The central macular thickness and central macular volume were measured. The integrity of the inner segment-outer segment junction and the integrity of the external limiting membrane were also evaluated in the same area.
  
  
  RESULTS
  Among the 28 eyes studied, 8 had normal autofluorescence. The remaining 20 eyes had abnormal autofluorescence: a hyper-cystoid autofluorescence in 5 eyes (25%), hyper-spot autofluorescence in 8 eyes (40%), and hypo-irregular autofluorescence in 5 eyes (25%). Best corrected visual acuity was significantly better in patients with normal autofluorescence and those with hyper-cystoid autofluorescence. There was no significant difference in central macular thickness (P=0.186) and central macular volume (P=0.191) between the four groups.
  
  
  CONCLUSIONS
  The autofluorescence is a simple, fast, and non-invasive technique for the study of diabetic macular edema with good correlation to the visual function as well as to the extent of damage to the retina. It is, therefore, a possible alternative to other invasive imaging techniques in particular in the long term monitoring of diabetic macular edema.
authors: Service d'ophtalmologie, CHU Mohamed Taher Maamouri de Nabeul, Mrezgua, 8000 Nabeul, Tunisie.
authors: W
authors: W
authors: Zbiba
authors: Service d'ophtalmologie, CHU Mohamed Taher Maamouri de Nabeul, Mrezgua, 8000 Nabeul, Tunisie. Electronic address: baba.atef@gmail.com.
authors: A
authors: A
authors: Baba
authors: Service d'ophtalmologie, CHU Mohamed Taher Maamouri de Nabeul, Mrezgua, 8000 Nabeul, Tunisie.
authors: E
authors: E
authors: Bouayed
authors: Service d'ophtalmologie, CHU Mohamed Taher Maamouri de Nabeul, Mrezgua, 8000 Nabeul, Tunisie.
authors: A
authors: A
authors: Daldoul
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003930:Diabetic Retinopathy / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008269:Macular Edema / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D061848:Optical Imaging; D011237:Predictive Value of Tests; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D058609:Visual Field Tests
keywords: Autofluorescence du fond d’œil; Diabetic macular edema; Fundus autofluorescence; Œdème maculaire diabétique