title: Is Hypovitaminosis D Associated with Stress Perception in the Elderly? A Nationwide Representative Study in Korea.
abstract: Hypovitaminosis D and stress are common problems among the elderly. The aim of this cross-sectional nationally representative study was to evaluate the association between hypovitaminosis D and stress perception using large-scale nationally representative data from the Korea National Health and Nutrition Examination Survey (2012-2013). In our study, a total of 1393 elders (≥65 years old) were included to evaluate the association between hypovitaminosis D and stress perception. Serum 25-hydroxyvitamin D levels were determined using radioimmunoassay, and perceived stress status was assessed by a self-reporting questionnaire. The association between hypovitaminosis D and stress perception according to sex was examined using logistic regression analysis. After multivariate adjustment for sociodemographic and lifestyle factors and comorbidities, hypovitaminosis D was significantly associated with perceived stress (odds ratio, 2.73; 95% confidence interval, 1.10-6.77;p= 0.029) among women; however, this association was not significant among men. Hypovitaminosis D was a risk factor for higher stress perception in older Korean women. Even though the role of vitamin D in stress perception is still unclear, we suggest screening for hypovitaminosis D among the elderly.
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. mieun0817@naver.com.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. mieun0817@naver.com.
authors: Mieun
authors: M
authors: Gwon
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. 03141998@naver.com.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. 03141998@naver.com.
authors: Young Jin
authors: YJ
authors: Tak
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. yujkim@pusan.ac.kr.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. yujkim@pusan.ac.kr.
authors: Yun Jin
authors: YJ
authors: Kim
authors: Medical Education Unit and Medical Research Institute, Pusan National University School of Medicine, Yangsan 626-870, Korea. saylee@pnu.edu.|Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National Yangsan Hospital, Yangsan 626-789, Korea. saylee@pnu.edu.
authors: Sang Yeoup
authors: SY
authors: Lee
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. eltidine@hanmail.net.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. eltidine@hanmail.net.
authors: Jeong Gyu
authors: JG
authors: Lee
authors: Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National Yangsan Hospital, Yangsan 626-789, Korea. dwjeong75@hanmail.net.
authors: Dong Wook
authors: DW
authors: Jeong
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. eeugus@hanmail.net.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. eeugus@hanmail.net.
authors: Yu Hyeon
authors: YH
authors: Yi
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. greatseunghun@hanmail.net.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. greatseunghun@hanmail.net.
authors: Seung Hoon
authors: SH
authors: Lee
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. hezera83@naver.com.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. hezera83@naver.com.
authors: Hye Rim
authors: HR
authors: Hwang
authors: Department of Family Medicine, Pusan National University School of Medicine, Busan 602-739, Korea. ylee23@daum.net.|Biomedical Research Institute, Pusan National University Hospital, Busan 602-739, Korea. ylee23@daum.net.
authors: Youngin
authors: Y
authors: Lee
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007118:Immunoassay; D016015:Logistic Models; D008297:Male; D009749:Nutrition Surveys; D016017:Odds Ratio; D056910:Republic of Korea; D012307:Risk Factors; D057566:Self Report; D012737:Sex Factors; D013315:Stress, Psychological / Q000097:blood / Q000209:etiology*; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications*
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: Korea; elderly; hypovitaminosis D; stress perception; vitamin D