title: Pure Large Cell Neuroendocrine Carcinoma of the Ovary with Metastasis to Cervix: A Rare Case Report and Review of Literature.
abstract: Ovarian Large Cell Neuroendocrine Carcinoma (LCNEC) is a recently described rare entity, which even more rarely occurs in a 'pure' form without any associated surface epithelial-stromal or germ cell component. Cervix metastasis of ovarian LCNEC has not been reported previously. We report here a case of ovarian LCNEC in a 35-year-old female who presented with abdominal pain and amenorrhea. Grossly the left ovary showed a solid cystic tumour measuring 6 cm in diameter. Histological examination showed a pure LCNEC without any associated component, confirmed by immunohistochemistry. Metastatic tumour deposits with numerous lymphovascular emboli were identified in the cervix. A comprehensive review of literature along with the various differential diagnosis is discussed.
authors: Assistant Professor, Department of Pathology, Govt Medical College , Kota, Rajasthan, India .
authors: Lakshmi
authors: L
authors: Agarwal
authors: Senior Resident, Department of Pathology, Govt Medical College , Kota, Rajasthan, India .
authors: Bhawna
authors: B
authors: Gupta
authors: Senior Resident, Department of Pathology, Govt Medical College , Kota, Rajasthan, India .
authors: Ayushi
authors: A
authors: Jain
keywords: Cervical metastasis; Poor prognosis; Pure