title: Prediction of post-operative pulmonary function after lobectomy for primary lung cancer: A comparison among counting method, effective lobar volume, and lobar collapsibility using inspiratory/expiratory CT.
abstract: OBJECTIVE
  To compare the predictabilities of postoperative pulmonary function after lobectomy for primary lung cancer among counting method, effective lobar volume, and lobar collapsibility.
  
  
  METHODS
  Forty-nine patients who underwent lobectomy for primary lung cancer were enrolled. All patients underwent inspiratory/expiratory CT and pulmonary function tests 2 weeks before surgery and postoperative pulmonary function tests 6-7 months after surgery. Pulmonary function losses (ΔFEV1.0and ΔVC) were calculated from the pulmonary function tests. Predictive postoperative pulmonary function losses (ppoΔFEV1.0and ppoΔVC) were calculated using counting method, effective volume, and lobar collapsibility. Correlations and agreements between ΔFEV1.0and ppoFEV1.0and those between ΔVC and ppoΔVC were tested among three methods using Spearman's correlation coefficient and Bland-Altman plots.
  
  
  RESULTS
  ΔFEV1.0and ppoΔFEV1.0insp-expwere strongly correlated (r=0.72), whereas ΔFEV1.0and ppoΔFEV1.0countand ΔFEV1.0and Pred. ΔFEV1.0eff.vol.were moderately correlated (r=0.50, 0.56). ΔVC and ppoΔVCeff.vol.(r=0.71) were strongly correlated, whereas ΔVC and ppoΔVCcount, and ΔVC and ppoΔVCinsp-expwere moderately correlated (r=0.55, 0.42).
  
  
  CONCLUSIONS
  Volumetry from inspiratory/expiratory CT data could be useful to predict postoperative pulmonary function after lobectomy for primary lung cancer.
authors: Department of Health Sciences, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: h-yabu@med.kyushu-u.ac.jp.
authors: Hidetake
authors: H
authors: Yabuuchi
authors: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: kawanami_01@mac.com.
authors: Satoshi
authors: S
authors: Kawanami
authors: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: kamitani@radiol.med.kyushu-u.ac.jp.
authors: Takeshi
authors: T
authors: Kamitani
authors: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: ymasato@radiol.med.kyushu-u.ac.jp.
authors: Masato
authors: M
authors: Yonezawa
authors: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: yyama@radiol.med.kyushu-u.ac.jp.
authors: Yuzo
authors: Y
authors: Yamasaki
authors: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: tora0228jp@yahoo.co.jp.
authors: Torahiko
authors: T
authors: Yamanouchi
authors: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: minagao@radiol.med.kyushu-u.ac.jp.
authors: Michinobu
authors: M
authors: Nagao
authors: Department of Surgery and Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: tatsuro@surg2.med.kyushu-u.ac.jp.
authors: Tatsuro
authors: T
authors: Okamoto
authors: Department of Clinical Radiology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. Electronic address: honda@radiol.med.kyushu-u.ac.jp.
authors: Hiroshi
authors: H
authors: Honda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D045853:Exhalation; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis* / Q000503:physiopathology; D011184:Postoperative Period; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012129:Respiratory Function Tests / Q000379:methods / Q000706:statistics & numerical data; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Forecasting; Lung neoplasms; Lung volume measurement; Multidetector computed tomography; Respiratory function tests