title: pyGeno: A Python package for precision medicine and proteogenomics.
abstract: pyGeno is a Python package mainly intended for precision medicine applications that revolve around genomics and proteomics. It integrates reference sequences and annotations from Ensembl, genomic polymorphisms from the dbSNP database and data from next-gen sequencing into an easy to use, memory-efficient and fast framework, therefore allowing the user to easily explore subject-specific genomes and proteomes. Compared to a standalone program, pyGeno gives the user access to the complete expressivity of Python, a general programming language. Its range of application therefore encompasses both short scripts and large scale genome-wide studies.
authors: Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada; Department of Biochemistry, Faculty of Medicine, Université de Montréal, Montreal, Canada.
authors: Tariq
authors: T
authors: Daouda
authors: Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada; Division of Hematology, Hôpital Maisonneuve-Rosemont, Montreal, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Canada.
authors: Claude
authors: C
authors: Perreault
authors: Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Canada; Department of Computer Science and Operations Research, Faculty of Arts and Sciences, Université de Montréal, Montreal, Canada.
authors: Sébastien
authors: S
authors: Lemieux
keywords: Bioinformatics; database; genetic polymorphisms; genomics; precision medicine; proteogenomics; proteomics; python