title: A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile).
abstract: BACKGROUND
  Matricaria recuitta chamomillais a plant that grows and is cultivated in some parts of Iran. The aim of this study was to overview the therapeutic effects of this valuable plant. This systematic review was aimed to introduceMatricaria recuitta chamomile, its chemical compounds, and its traditional usages.
  
  
  METHODS
  This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. The initial search strategy identified about 87 references. In this study, 69 studies were accepted for further screening and met all our inclusion criteria [in English, full text, therapeutic effects ofMatricaria recuitta chamomilla Land dated mainly from the year 1990 to 2016]. The search terms were "Matricaria recuitta chamomilla L.," "therapeutic properties," "pharmacological effects."
  
  
  RESULTS
  It is commonly used for its antioxidant, antimicrobial, antidepressant, anti-inflammatory, antidiarrheal activities, angiogenesis activity, anticarcinogenic, hepatoprotective, and antidiabetic effects. Besides, it is beneficial for knee osteoarthritis, ulcerative colitis, premenstrual syndrome, and gastrointestinal disorders.
  
  
  CONCLUSIONS
  Matricaria recuitta chamomilla L. is widely used for therapeutic and nontherapeutic purposes that trigger its significant value. Various combinations and numerous medicinal properties of its extract, oil, and leaves demand further studies about other useful and unknown properties of this multipurpose plant.
authors: M.D., Gynecologist, Fellowship of Infertility, Assistant Professor, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
authors: Sepide
authors: S
authors: Miraj
authors: MD, Assistant Professor of Rheumatology and internal medicine, Department of Rheumatology, Internal Medicine, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors: Samira
authors: S
authors: Alesaeidi
keywords: Matricaria recuitta chamomilla L; alternative and complementary medicine; pharmacognosy; phytochemicals; therapeutic effects