title: SOME CLINICALLY IMPORTANT ERYTHROCYTE BLOOD GROUP ANTIGENS IN DONORS.
abstract: The distribution of erythrocyte blood group antigens was evaluated among 656 donors; samples were provided by the diagnostic laboratory "Medina" Ltd Health Centre of Batumi. Lab analysis of the sample was conducted by the immunogenetics laboratory at Batumi Shota Rustaveli State University. The frequency of the ABO allele system in donors was as follows: r (0.70), q (0.23), p (0.07). The distribution of Rhesus (Rh) factor in the donor population was as follows: Rh(-) was found among 16.3±1.43% of investigated donors; the Rh(+) phenotype was found in 83.7±1.43% of donors. Additionally, the CcDee phenotype frequency was 29.9±1.78%; CCD-ee was 17.2±1.47%; ccddee was 14.9±1.38%; and CcD-Ee was 13.9±1.34%; ccD-Ee phenotype was 11.1±1.22%; ccD-ee was 5.5±0.88%; same phenotype indicators -2.1±0.55 were observed for CcD-EE and ccD-EE; CCD-Ee was 1.4±0.45%, CCD-EE was 0.4±0.26%; and finally, the frequency of Ccddee phenotype amounts was 1.1±0.40%, ccddEe and CCddee phenotypes were both 0.2±0.17%. The analysis of the Kell system allele revealed a low frequency for the p allele at 0.05, whereas the frequency of the q allele was 0.95. This large epidemiologic analysis of donor blood provides valuable information for hematological and transfusion centers to inform the preparation of blood components for transfusion.
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia.
authors: I
authors: I
authors: Tsintsadze
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia.
authors: T
authors: T
authors: Gorgoshadze
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia.
authors: S
authors: S
authors: Donskov
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia.
authors: L
authors: L
authors: Akhvlediani
authors: Batumi Shota Rustaveli State University, Faculty of Natural Sciences and Health Care, Department of Biology, Georgia.
authors: M
authors: M
authors: Nagervadze
mesh_terms: D000017:ABO Blood-Group System / Q000097:blood / Q000235:genetics; D001782:Blood Donors; D001789:Blood Group Antigens / Q000097:blood / Q000235:genetics*; D001788:Blood Grouping and Crossmatching; D004912:Erythrocytes / Q000276:immunology*; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D007626:Kell Blood-Group System / Q000097:blood / Q000235:genetics; D010641:Phenotype; D012204:Rh-Hr Blood-Group System / Q000097:blood / Q000235:genetics
chemical_list: D000017:ABO Blood-Group System; D001789:Blood Group Antigens; D007626:Kell Blood-Group System; D012204:Rh-Hr Blood-Group System