title: A Shake&Read distance-based microfluidic chip as a portable quantitative readout device for highly sensitive point-of-care testing.
abstract: Despite the rapid development of point-of-care testing (POCT) devices in recent years, quantitative POCT is still not readily available. Herein, we developed a simple, disposable and equipment-free quantitative POCT platform, the Shake&Read distance-based microfluidic Chip (S&R-μChip), for visual quantitative POCT and demonstrated its use in Enzyme-Linked Immunosorbent Assay (ELISA) for the detection of disease biomarkers.
authors: MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
authors: Yi
authors: Y
authors: Xie
authors: MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, P. R. China. zylin@fzu.edu.cn.
authors: Xiaofeng
authors: X
authors: Wei
authors: Xiamen University Affiliated Keji High School, Xiamen 361005, P. R. China.
authors: Qizhen
authors: Q
authors: Yang
authors: MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
authors: Zhichao
authors: Z
authors: Guan
authors: MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
authors: Dan
authors: D
authors: Liu
authors: MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
authors: Xuan
authors: X
authors: Liu
authors: MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
authors: Leiji
authors: L
authors: Zhou
authors: MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
authors: Zhi
authors: Z
authors: Zhu
authors: MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, P. R. China. zylin@fzu.edu.cn.
authors: Zhenyu
authors: Z
authors: Lin
authors: MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
authors: Chaoyong
authors: C
authors: Yang
mesh_terms: D015415:Biomarkers / Q000032:analysis; D004194:Disease; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D046210:Microfluidic Analytical Techniques; D000067716:Point-of-Care Testing
chemical_list: D015415:Biomarkers