title: Herpes Simplex Encephalitis of the Parietal Lobe: A Rare Presentation.
abstract: A 69-year-old female with a history of breast cancer and hypertension presented with a rare case of herpes simplex encephalitis (HSE) isolated to her left parietal lobe. The patient's first biopsy was negative for herpes simplex virus (HSV) I/II antigens, but less than two weeks later, the patient tested positive on repeat biopsy. This initial failure to detect the virus and the similarities between HSE and symptoms of intracranial hemorrhage (ICH) suggests repeat testing for HSV in the presence of ICH. Due to the frequency of patients with extra temporal HSE, a diagnosis of HSE should be more readily considered, particularly when a patient may not be improving and a concrete diagnosis has not been solidified.
authors: Orthopedic Surgery, Swedish Neuroscience Institute ; Department of Trauma Surgery, BG University Hospital Bergmannsheil, Bochum, Germany.
authors: Christian
authors: C
authors: Fisahn
authors: Neurosurgery, Swedish Neuroscience Institute.
authors: Lara
authors: L
authors: Tkachenko
authors: Seattle Science Foundation ; Neurological Surgery, Wayne State University.
authors: Marc
authors: M
authors: Moisi
authors: Pathology, CellNetix.
authors: Steven
authors: S
authors: Rostad
authors: Anatomy, St. George's University School of Medicine.
authors: Randle
authors: R
authors: Umeh
authors: Anesthesiology and Critical Care, Houston Methodist Hospital.
authors: Michael E
authors: ME
authors: Zwillman
authors: Neurosurgery, Seattle Science Foundation.
authors: R Shane
authors: RS
authors: Tubbs
authors: Neurosurgery, Swedish Neuroscience Institute.
authors: Jeni
authors: J
authors: Page
authors: Neurosurgery, Swedish Neuroscience Institute.
authors: David W
authors: DW
authors: Newell
authors: Chief of Neurosurgery, Swedish Neuroscience Institute.
authors: Johnny B
authors: JB
authors: Delashaw
keywords: central nervous system; herpes simplex encephalitis; parietal lobe; virus