title: Dual Intravitreal Injections With Foscarnet and Ganciclovir for Ganciclovir-Resistant Recurrent Cytomegalovirus Retinitis in a Congenitally Infected Infant.
abstract: Resistant strains of cytomegalovirus can be difficult to treat in cases of congenital cytomegalovirus retinitis. The authors describe a case of recurrent bilateral congenital cytomegalovirus retinitis in an immunocompetent newborn with ganciclovir resistance successfully treated uniquely with dual therapy of intravenous ganciclovir and foscarnet and dual intravitreal injections with ganciclovir and foscarnet. [J Pediatr Ophthalmol Strabismus. 2016;53:e58-e60.].
authors: Joseph D
authors: JD
authors: Boss
authors: Kevin
authors: K
authors: Rosenberg
authors: Rajiv
authors: R
authors: Shah
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D003587:Cytomegalovirus / Q000502:physiology; D017726:Cytomegalovirus Retinitis / Q000151:congenital / Q000175:diagnosis / Q000188:drug therapy*; D024882:Drug Resistance, Viral / Q000187:drug effects*; D004359:Drug Therapy, Combination; D005260:Female; D017245:Foscarnet / Q000627:therapeutic use*; D015774:Ganciclovir / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D058449:Intravitreal Injections; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy*; D012008:Recurrence; D019562:Viral Load; D014822:Vitreous Body / Q000821:virology
chemical_list: D000998:Antiviral Agents; D017245:Foscarnet; D015774:Ganciclovir