title: Versatile Catalytic Hydrogenation Using A Simple Tin(IV) Lewis Acid.
abstract: Despite the rapid development of frustrated Lewis pair (FLP) chemistry over the last ten years, its application in catalytic hydrogenations remains dependent on a narrow family of structurally similar early main-group Lewis acids (LAs), inevitably placing limitations on reactivity, sensitivity and substrate scope. Herein we describe the FLP-mediated H2activation and catalytic hydrogenation activity of the alternative LA iPr3SnOTf, which acts as a surrogate for the trialkylstannylium ion iPr3Sn+, and is rapidly and easily prepared from simple, inexpensive starting materials. This highly thermally robust LA is found to be competent in the hydrogenation of a number of different unsaturated functional groups (which is unique to date for main-group FLP LAs not based on boron), and also displays a remarkable tolerance to moisture.
authors: Department of Chemistry, Imperial College London, London, SW7 2AZ, UK.
authors: Daniel J
authors: DJ
authors: Scott
authors: Department of Chemistry, Imperial College London, London, SW7 2AZ, UK.
authors: Nicholas A
authors: NA
authors: Phillips
authors: Department of Chemistry, Imperial College London, London, SW7 2AZ, UK.
authors: Joshua S
authors: JS
authors: Sapsford
authors: Department of Chemistry, Imperial College London, London, SW7 2AZ, UK.
authors: Arron C
authors: AC
authors: Deacy
authors: Department of Chemistry, Imperial College London, London, SW7 2AZ, UK.
authors: Matthew J
authors: 0000-0002-1767-7072
authors: MJ
authors: Fuchter
authors: Department of Chemistry, Imperial College London, London, SW7 2AZ, UK.
authors: Andrew E
authors: 0000-0002-5575-7866
authors: AE
authors: Ashley
keywords: catalysis; frustrated Lewis pairs; hydrogenation; stannylium; tin