title: Functional Mitral Regurgitation: Appraising the Evidence Behind Recommended Treatment Strategies.
abstract: Functional mitral regurgitation (MR) is the most common type of MR encountered in clinical practice. Because the disease arises from the ventricular aspect of the mitral valve apparatus, treatment therapies are less defined and outcomes are poor. In this review, the state of evidence for medical and surgical therapy in functional MR is appraised. Future directions for research in this area are also defined.
authors: Division of Cardiology, Department of Medicine, Duke University, Durham, NC, 27710, USA. zainab.samad@duke.edu.
authors: Zainab
authors: Z
authors: Samad
authors: Division of Cardiology, Department of Medicine, Duke University, Durham, NC, 27710, USA.|Duke Clinical Research Institute, Duke University, Durham, NC, USA.
authors: Eric J
authors: EJ
authors: Velazquez
mesh_terms: D018450:Disease Progression; D004452:Echocardiography; D019317:Evidence-Based Medicine; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000503:physiopathology / Q000601:surgery; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
keywords: Functional mitral regurgitation; Medical therapy; Mitraclip; Mitral valve replacement; Surgery