title: Short-chain fatty acids in control of energy metabolism.
abstract: Short-chain fatty acids (SCFAs), especially acetate, propionate and butyrate, are the end products from the intestinal microbial fermentation of dietary fibers and resistant starch. It has been well documented that plasma and colonic SCFAs are associated with metabolic syndromes. Recently, the involvement of SCFAs in energy homeostasis regulation has been extensively studied. The importance of SCFAs on energy metabolism has highlighted the potential of modulating SCFAs as a nutritional target to prevent and counteract metabolism disorders and its associated diseases such as obesity and type 2 diabetes. Here, we summarize the current knowledge about the biological properties of SCFAs with their impact on the energy homeostasis.
authors: a College of Food Science , Fujian Agriculture and Forestry University , Fuzhou , Fujian , P.R. China.|b Translational & Experimental Medicine, Division of Biomedical Sciences, Warwick Medical School , University of Warwick , Coventry , UK.
authors: Jiamiao
authors: J
authors: Hu
authors: a College of Food Science , Fujian Agriculture and Forestry University , Fuzhou , Fujian , P.R. China.
authors: Shaoling
authors: S
authors: Lin
authors: a College of Food Science , Fujian Agriculture and Forestry University , Fuzhou , Fujian , P.R. China.
authors: Baodong
authors: B
authors: Zheng
authors: c School of Life Sciences , The Chinese University of Hong Kong , Shatin, New Territories , Hong Kong SAR.
authors: Peter C K
authors: PCK
authors: Cheung
mesh_terms: D000818:Animals; D004032:Diet; D004734:Energy Metabolism / Q000187:drug effects* / Q000502:physiology; D005232:Fatty Acids, Volatile / Q000494:pharmacology*; D006801:Humans
chemical_list: D005232:Fatty Acids, Volatile
keywords: GPR41/43; Short-chain fatty acids; energy homeostasis; gut health