title: Macroporous Poly(GMA-co-EGDMA) for Enzyme Stabilization.
abstract: One of the most used procedures for enzyme stabilization is immobilization. Although immobilization on solid supports has been pursued since the 1950s, there are no general rules for selecting the best support for a giving application. A macroporous copolymer of ethylene glycol dimethacrylate and glycidyl methacrylate (poly (GMA-co-EGDMA)) is a carrier consisting of macroporous beads for immobilizing enzymes of industrial potential for the production of fine chemicals and pharmaceuticals.
authors: Division of Experimental Therapeutics, Department of Medicine, Columbia University, 630 West 168th Street, P&S 8-436, New York, NY, 10032, USA. nm2729@columbia.edu.
authors: Nenad B
authors: NB
authors: Milosavić
authors: Department of Biochemistry, Faculty of Chemistry, University of Belgrade, Studentski trg 16, Belgrade, 11000, Serbia.
authors: Radivoje M
authors: RM
authors: Prodanović
authors: Department of Biochemistry, Faculty of Chemistry, University of Belgrade, Studentski trg 16, Belgrade, 11000, Serbia.
authors: Dušan
authors: D
authors: Velićković
authors: Department of Biochemistry, Faculty of Chemistry, University of Belgrade, Studentski trg 16, Belgrade, 11000, Serbia.
authors: Aleksandra
authors: A
authors: Dimitrijević
mesh_terms: D001234:Aspergillus niger / Q000737:chemistry / Q000201:enzymology* / Q000378:metabolism; D003432:Cross-Linking Reagents / Q000737:chemistry*; D004795:Enzyme Stability; D004800:Enzymes, Immobilized / Q000737:chemistry* / Q000378:metabolism; D005026:Ethylene Glycols / Q000737:chemistry*; D005027:Ethylene Oxide / Q000737:chemistry; D005087:Glucan 1,4-alpha-Glucosidase / Q000737:chemistry* / Q000378:metabolism; D005976:Glutaral / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry*; D010084:Oxidation-Reduction; D016062:Porosity
chemical_list: D003432:Cross-Linking Reagents; D004800:Enzymes, Immobilized; D005026:Ethylene Glycols; D008689:Methacrylates; C526534:poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate); D005087:Glucan 1,4-alpha-Glucosidase; D005027:Ethylene Oxide; D005976:Glutaral
keywords: Covalent immobilization; Enzyme stabilization; Glutaraldehyde; Macroporous; Periodate; Poly (GMA-co-EGDMA)