title: Incidence of Endemic Burkitt Lymphoma in Three Regions of Mozambique.
abstract: Data on the burden and incidence of endemic Burkitt lymphoma (eBL) across Mozambique are scarce. We retrospectively retrieved information on eBL cases from reports of the three main hospitals of Mozambique: Maputo Central Hospital (MCH), Beira Central Hospital (BCH), and Nampula Central Hospital (NCH) between 2004 and 2014. For 2015, we prospectively collected information of new eBL cases attending these hospitals. A total of 512 eBL cases were reported between 2004 and 2015: 153 eBL cases were reported in MCH, 195 in BCH, and 164 in NCH. Mean age of cases was 6.9 years (standard deviation = 2.8); 63% (319/504) of cases were males. For 2015, the estimated incidence rate of eBL was 2.0, 1.7, and 3.9 per 106person-year at risk in MCH, BCH, and NCH, respectively. Incidence was higher in NCH (northern Mozambique), where intensity of malaria transmission is higher. Data presented show that eBL is a common pediatric malignancy in Mozambique, as observed in neighboring countries.
authors: ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. cocallaghan@creal.cat.|Universitat Pompeu Fabra (UPF), Barcelona, Spain.|CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
authors: Cristina
authors: C
authors: O'Callaghan-Gordo
authors: CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Unit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
authors: Delphine
authors: D
authors: Casabonne
authors: Serviço de Anatomia Patológica, Hospital Central do Maputo, Maputo, Mozambique.|Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique.
authors: Carla
authors: C
authors: Carrilho
authors: Serviço de Anatomia Patológica, Hospital Central da Beira, Beira, Mozambique.|Universidade Católica de Moçambique, Beira, Mozambique.
authors: Josefo
authors: J
authors: Ferro
authors: Serviço de Anatomia Patológica, Hospital Central do Maputo, Maputo, Mozambique.|Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique.|Programa Nacional de Controle do Cancro, Ministério da Saúde, Maputo, Mozambique.
authors: Cesaltina
authors: C
authors: Lorenzoni
authors: Serviço de Anatomia Patológica, Hospital Central do Nampula, Nampula, Mozambique.|Faculdade de Ciências de Saúde, Universidade Lúrio, Nampula, Mozambique.
authors: Clesio
authors: C
authors: Zaqueu
authors: Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
authors: Augusto
authors: A
authors: Nhabomba
authors: ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
authors: Ruth
authors: R
authors: Aguilar
authors: Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.|ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
authors: Quique
authors: Q
authors: Bassat
authors: CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Unit of Infections and Cancer (UNIC), IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, Spain.
authors: Sílvia
authors: S
authors: de Sanjosé
authors: Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.|ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
authors: Carlota
authors: C
authors: Dobaño
authors: ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.|Universitat Pompeu Fabra (UPF), Barcelona, Spain.|CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona, Spain.
authors: Manolis
authors: M
authors: Kogevinas
mesh_terms: D000293:Adolescent; D002051:Burkitt Lymphoma / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D009073:Mozambique / Q000453:epidemiology; D012189:Retrospective Studies