title: Brazilian borreliosis with special emphasis on humans and horses.
abstract: Borreliosis caused by Borrelia burgdorferi sensu lato is a cosmopolitan zoonosis studied worldwide; it is called Lyme disease in many countries of the Northern Hemisphere and Lyme-like or Baggio-Yoshinari Syndrome in Brazil. However, despite the increasing number of suspect cases, this disease is still neglected in Brazil by the medical and veterinary communities. Brazilian Lyme-like borreliosis likely involves capybaras as reservoirs and Amblyomma and Rhipicephalus ticks as vectors. Thus, domestic animals can serve as key carriers in pathogen dissemination. This zoonosis has been little studied in horses in Brazil. The first survey was performed in the state of Rio de Janeiro, and this Brazilian Borreliosis exhibits many differences from the disease widely described in the Northern Hemisphere. The etiological agent shows different morphological and genetic characteristics, the disease has a higher recurrence rate after treatment with antibiotics, and the pathogen stimulates intense symptoms such as a broader immune response in humans. Additionally, the Brazilian zoonosis is not transmitted by the Ixodes ricinus complex. With respect to clinical manifestations, Baggio-Yoshinari Syndrome has been reported to cause neurological, cardiac, ophthalmic, muscle, and joint alterations in humans. These symptoms can possibly occur in horses. Here, we present a current panel of studies involving the disease in humans and equines, particularly in Brazil.
authors: Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal, São Paulo, SP, Brazil. Electronic address: basile.roberta@gmail.com.
authors: Roberta Carvalho
authors: RC
authors: Basile
authors: Universidade de São Paulo, Departamento de reumatologia, São Paulo, SP, Brazil.
authors: Natalino Hajime
authors: NH
authors: Yoshinari
authors: Universidade de São Paulo, Departamento de reumatologia, São Paulo, SP, Brazil.
authors: Elenice
authors: E
authors: Mantovani
authors: Universidade de São Paulo, Departamento de reumatologia, São Paulo, SP, Brazil.
authors: Virgínia Nazário
authors: VN
authors: Bonoldi
authors: Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal, São Paulo, SP, Brazil.
authors: Delphim da Graça
authors: DD
authors: Macoris
authors: Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal, São Paulo, SP, Brazil.
authors: Antonio de
authors: A
authors: Queiroz-Neto
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D025065:Borrelia burgdorferi / Q000235:genetics* / Q000276:immunology*; D001938:Brazil / Q000453:epidemiology; D006734:Horse Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology* / Q000635:transmission; D006736:Horses; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology* / Q000635:transmission; D015047:Zoonoses
chemical_list: D000900:Anti-Bacterial Agents
keywords: Baggio-Yoshinari Syndrome; Borrelia burgdorferi; Equine; Ticks; Zoonosis