title: Phosphine-Catalyzed Enantioselective [4 + 3] Annulation of Allenoates with C,N-Cyclic Azomethine Imines: Synthesis of Quinazoline-Based Tricyclic Heterocycles.
abstract: With the use of a commercially available chiral phosphine as the catalyst, the first catalytic enantioselective [4 + 3] annulation of allenoates with C,N-cyclic azomethine imines is developed. The reaction works efficiently under mild reaction conditions to afford seven-membered ring-fused quinazoline-based tricyclic heterocycles in high yields with good to excellent diastereo- and enantioselectivities.
authors: Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
authors: Chunhao
authors: C
authors: Yuan
authors: Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
authors: Leijie
authors: L
authors: Zhou
authors: Institute of High Energy Physics, Chinese Academy of Science , Beijing 100049, P. R. China.
authors: Miaoren
authors: M
authors: Xia
authors: Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
authors: Zhanhu
authors: Z
authors: Sun
authors: Institute of High Energy Physics, Chinese Academy of Science , Beijing 100049, P. R. China.
authors: Dongqi
authors: D
authors: Wang
authors: Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.|Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University , Guiyang 550025, China.
authors: Hongchao
authors: H
authors: Guo