title: Fluorescent Detection of Phosphate Ion via a Tetranuclear Zinc Complex Supported by a Tetrakisquinoline Ligand and μ4-PO4Core.
abstract: The tetrakisquinoline ligand HT(6-MeO8Q)HPN (N,N,N',N'-tetrakis(6-methoxy-8-quinolylmethyl)-2-hydroxy-1,3-propanediamine) exhibited Zn2+-induced fluorescence enhancement with high specificity and sensitivity (IZn/I0= 57 and ICd/IZn= 6% in the presence of 2 equiv of Zn2+; LOD (limit of detection) = 15 nM). This ligand also exhibited fluorescence enhancement specific to inorganic phosphate (PO43-) in DMF-HEPES buffer (50 mM HEPES, 100 mM KCl, pH = 7.5) (1:1) in the presence of 2 equiv of Zn2+. The structure of the unprecedented tetranuclear zinc complex with a μ4-PO4bridge was elucidated by X-ray crystallography as the key species responsible for fluorescence enhancement.
authors: Yuji
authors: Y
authors: Mikata
authors: Risa
authors: R
authors: Ohnishi
authors: Risa
authors: R
authors: Nishijima
authors: National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.
authors: Hideo
authors: H
authors: Konno