title: Detection of Astrovirus in Historical Cases of European Sporadic Bovine Encephalitis, Switzerland 1958-1976.
abstract: European sporadic bovine encephalitis is a frequent diagnosis in neurologically diseased cattle, but its etiology remained unresolved. Usingin situhybridization, we have detected a recently discovered neurotropic bovine astrovirus in historical tissues in a high proportion of brain samples of affected cattle. Our results suggest that astroviruses were already involved in the pathogenesis of the disease several decades ago, but have gone undetected.
authors: DCR-VPH, Division of Neurological Sciences, NeuroCenter, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
authors: Senija
authors: S
authors: Selimovic-Hamza
authors: DCR-VPH, Division of Neurological Sciences, NeuroCenter, University of Bern , Bern , Switzerland.
authors: Ilias G
authors: IG
authors: Bouzalas
authors: DCR-VPH, Division of Neurological Sciences, NeuroCenter, University of Bern , Bern , Switzerland.
authors: Marc
authors: M
authors: Vandevelde
authors: DCR-VPH, Division of Neurological Sciences, NeuroCenter, University of Bern , Bern , Switzerland.
authors: Anna
authors: A
authors: Oevermann
authors: DCR-VPH, Division of Neurological Sciences, NeuroCenter, University of Bern , Bern , Switzerland.
authors: Torsten
authors: T
authors: Seuberlich
keywords: archive; astrovirus; cattle; encephalitis; historical; neurological disease