title: Germinated Pigmented Rice (Oryza Sativa L. cv. Superhongmi) Improves Glucose and Bone Metabolisms in Ovariectomized Rats.
abstract: The effect of germinated Superhongmi, a reddish brown pigmented rice cultivar, on the glucose profile and bone turnover in the postmenopausal-like model of ovariectomized rats was determined. The ovariectomized Sprague-Dawley rats were randomly divided into three dietary groups (n= 10): normal control diet (NC) and normal diet supplemented with non-germinated Superhongmi (SH) or germinated Superhongmi (GSH) rice powder. After eight weeks, the SH and GSH groups showed significantly lower body weight, glucose and insulin concentrations, levels of bone resorption markers and higher glycogen and 17-β-estradiol contents than the NC group. The glucose metabolism improved through modulation of adipokine production and glucose-regulating enzyme activities. The GSH rats exhibited a greater hypoglycemic effect and lower bone resorption than SH rats. These results demonstrate that germinated Superhongmi rice may potentially be useful in the prevention and management of postmenopausal hyperglycemia and bone turnover imbalance.
authors: Department of Food Science and Nutrition, Brain Korea 21 Plus, Kyungpook National University, Daegu 41566, Korea. zizibe0312@nate.com.
authors: Soo Im
authors: SI
authors: Chung
authors: Department of Agricultural Science, Korea National Open University, Seoul 03087, Korea. ryusn@knou.ac.kr.
authors: Su Noh
authors: SN
authors: Ryu
authors: Department of Food Science and Nutrition, Brain Korea 21 Plus, Kyungpook National University, Daegu 41566, Korea. mykang@knu.ac.kr.
authors: Mi Young
authors: MY
authors: Kang
mesh_terms: D054392:Adipokines / Q000096:biosynthesis; D000818:Animals; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism*; D001835:Body Weight / Q000187:drug effects; D001862:Bone Resorption / Q000097:blood* / Q000178:diet therapy; D001842:Bone and Bones / Q000187:drug effects* / Q000378:metabolism; D019587:Dietary Supplements; D004958:Estradiol / Q000097:blood; D005260:Female; D018525:Germination; D006003:Glycogen / Q000097:blood; D006943:Hyperglycemia / Q000097:blood* / Q000178:diet therapy / Q000201:enzymology; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D007328:Insulin / Q000097:blood; D012275:Oryza; D010052:Ovariectomy; D017698:Postmenopause; D011897:Random Allocation; D017207:Rats, Sprague-Dawley
chemical_list: D054392:Adipokines; D015415:Biomarkers; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D004958:Estradiol; D006003:Glycogen
keywords: Superhongmi; bone metabolism; germination; glucose; pigmented rice