title: Multiple giant cell tumors of bone arising from multiple fatty tumors.
abstract: We describe a patient with a history of giant cell tumor who over the course of 18 years developed multiple fat containing osseous lesions in the pelvis and spine. Two of these lesions subsequently evolved into biopsy proven giant cell tumor of bone. To our knowledge, this phenomenon of giant cell tumors evolving from fat containing lesions has not been described.
authors: Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Yawkey 6E, 55 Fruit Street, Boston, MA, 02114, USA.
authors: Alireza
authors: A
authors: Eajazi
authors: Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Yawkey 6E, 55 Fruit Street, Boston, MA, 02114, USA. akheterpal@mgh.harvard.edu.
authors: Arvin
authors: A
authors: Kheterpal
authors: Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Yawkey 6E, 55 Fruit Street, Boston, MA, 02114, USA.
authors: Susan
authors: S
authors: Kattapuram
authors: Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Warren 2, 55 Fruit Street, Boston, MA, USA.
authors: Gunnlaugur Petur
authors: GP
authors: Nielsen
authors: Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Yawkey 6E, 55 Fruit Street, Boston, MA, 02114, USA.
authors: Daniel Ira
authors: DI
authors: Rosenthal
mesh_terms: D000328:Adult; D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008068:Lipomatosis / Q000473:pathology*; D008297:Male; D010386:Pelvic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy
keywords: Bone; Fatty tumor; Giant cell tumor (GCT); Multifocal; Recurrent