title: Biotechnological intervention in betelvine (Piper betle L.): A review on recent advances and future prospects.
abstract: Betelvine (Piper betle L.) is cultivated for its deep green heart shaped leaf for (15-20) million Indian and 2 billion foreign consumers annually. The crop provides Rs (6000-7000) million of national income per year and at the same time leaves worth Rs (30-40) million is exported to other countries. The leaves are not only used directly for chewing purposes but also possesses antioxidant, anti-inflammatory, anti-apoptotic, anti-cancer and anti-microbial properties. Besides, the leaves also contain eugenol rich essential oil (1%-3%) which is the source for medicine, stimulant, antiseptic, tonic and other ayurvedic formulations. The essential oil also contains chavibetol, caryophyllene and methyl eugenol which are the potent source for preparation in ayurvedic medicine and herbal products. Cost of betelvine essential oil is 10$ per 5 mL. In spite of its great economical and medicinal importance betelvine is still neglected by the researchers for proper characterization and authentication for selection of elite landraces. Lack of awareness among people, use of same planting material for many generations, existing of many synonyms for a single landraces, no proper characterization of available landraces are some of the significant constraints for its commercialization. Our review endeavours a complete advance in the research on betelvine, existing lacunae for its proper characterization and commercial cultivation. It also attempts to provide a comprehensive account on biotechnological interventions made in betelvine aimed at complementing conventional programmes for improvement of this nutraceutically important cash crop.
authors: Centre of Biotechnology, School of Pharmaceutical Sciences, Siksha O Anusandhan University, Bhubaneswar 751003, Odisha, India.
authors: Suryasnata
authors: S
authors: Das
authors: Centre of Biotechnology, School of Pharmaceutical Sciences, Siksha O Anusandhan University, Bhubaneswar 751003, Odisha, India.
authors: Reena
authors: R
authors: Parida
authors: Centre of Biotechnology, School of Pharmaceutical Sciences, Siksha O Anusandhan University, Bhubaneswar 751003, Odisha, India.
authors: I
authors: I
authors: Sriram Sandeep
authors: Centre of Biotechnology, School of Pharmaceutical Sciences, Siksha O Anusandhan University, Bhubaneswar 751003, Odisha, India.
authors: Sanghamitra
authors: S
authors: Nayak
authors: Centre of Biotechnology, School of Pharmaceutical Sciences, Siksha O Anusandhan University, Bhubaneswar 751003, Odisha, India. Electronic address: sujatamohantyils@gmail.com.
authors: Sujata
authors: S
authors: Mohanty
keywords: Betelvine (Piper betle L.); Bioactivity; Commercial cultivation; Eugenol; Medicinal uses