title: Natural Occurrence of Alternaria Toxins in the 2015 Wheat from Anhui Province, China.
abstract: The exposure toAlternariatoxins from grain and grain-based products has been reported to be related to human esophageal cancer in China. In this study, a total of 370 freshly harvested wheat kernel samples collected from Anhui province of China in 2015 were analyzed for the fourAlternariatoxins tenuazonic acid (TeA), tentoxin (TEN), alternariol (AOH) and alternariol monomethyl ether (AME) by high performance liquid chromatography-tandem mass spectrometry method (HPLC-MS/MS). TeA was the predominant toxin detected followed by TEN, AOH and AME. The concentrations of the fourAlternariatoxins varied geographically. The samples from Fuyang district showed higher TEN concentration levels than the other regions studied (p< 0.05). Furthermore, 95% (352/370) of the wheat samples were positive for more than one type ofAlternariatoxins. Positive correlation was observed between concentration levels of TeA and TEN, AOH and AME, TeA and AOH, and the total dibenzopyrone derivatives (AOH + AME) and TeA. Results indicate that there is a need to set the tolerance limit forAlternariatoxins in China, and more data on the contamination of these toxins in agro-products is required.
authors: Key Laboratory of Food Safety Risk Assessment, Ministry of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China. wenjingxu_vip@163.com.|Institute of Nutrition and Food Hygiene, West China College of Public Health, Sichuan University, Chengdu 610041, China. wenjingxu_vip@163.com.
authors: Wenjing
authors: W
authors: Xu
authors: Key Laboratory of Food Safety Risk Assessment, Ministry of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China. hanxiaomin@cfsa.net.cn.
authors: Xiaomin
authors: X
authors: Han
authors: Key Laboratory of Food Safety Risk Assessment, Ministry of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China. lifengqin@cfsa.net.cn.
authors: Fengqin
authors: F
authors: Li
authors: Institute of Nutrition and Food Hygiene, West China College of Public Health, Sichuan University, Chengdu 610041, China. lishizhang_56@163.com.
authors: Lishi
authors: L
authors: Zhang
mesh_terms: D000528:Alternaria; D002681:China; D002851:Chromatography, High Pressure Liquid; D004784:Environmental Monitoring; D005506:Food Contamination / Q000032:analysis; D009183:Mycotoxins / Q000032:analysis*; D053719:Tandem Mass Spectrometry; D014908:Triticum / Q000737:chemistry*
chemical_list: D009183:Mycotoxins
keywords: Alternaria toxins; China; HPLC-MS/MS; wheat