title: Current progress toward vaccine and passive immunization approaches for Strongyloides spp.
abstract: Strongyloides stercoralis is a helminth parasite that can infect millions of people worldwide, particularly in tropical, subtropical and temperate regions with poor sanitation. Several aspects of epidemiology, biology and host-parasite interactions of S. stercoralis have been studied, and substantial knowledge has been acquired; however, very few studies on immunotherapeutic control strategies to prevent infection and disease in humans have been conducted. Therefore, this article reviews the current progress and targets toward vaccine and passive immunization approaches for Strongyloides spp.
authors: Departamento de Microbiologia, Imunologia e Parasitologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil.
authors: Marcelo Arantes
authors: MA
authors: Levenhagen
authors: Departamento de Biotecnologia, Genética e Biologia Celular, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
authors: Hélio
authors: H
authors: Conte
authors: Departamento de Microbiologia, Imunologia e Parasitologia, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil. Electronic address: costacruz@ufu.br.
authors: Julia Maria
authors: JM
authors: Costa-Cruz
mesh_terms: D000818:Animals; D006790:Host-Parasite Interactions / Q000276:immunology; D006801:Humans; D007116:Immunization, Passive / Q000379:methods; D017171:Strongyloides stercoralis / Q000276:immunology*; D013322:Strongyloidiasis / Q000276:immunology* / Q000517:prevention & control*; D014612:Vaccines / Q000276:immunology*
chemical_list: D014612:Vaccines
keywords: Passive immunization; Strongyloides spp.; Strongyloidosis; Vaccine