title: ESBL-Producing and Macrolide-Resistant Shigella sonnei Infections among Men Who Have Sex with Men, England, 2015.
abstract: In England in 2015, Shigella sonnei isolates from men who have sex with men produced extended-spectrum β-lactamases and exhibited macrolide resistance. Whole-genome sequencing showed a close relationship among the isolates, which harbored a plasmid that was previously identified in a shigellosis outbreak among this population but has acquired a mobile element.
authors: Piers
authors: P
authors: Mook
authors: Jacquelyn
authors: J
authors: McCormick
authors: Manpreet
authors: M
authors: Bains
authors: Lauren A
authors: LA
authors: Cowley
authors: Marie A
authors: MA
authors: Chattaway
authors: Claire
authors: C
authors: Jenkins
authors: Amy
authors: A
authors: Mikhail
authors: Gwenda
authors: G
authors: Hughes
authors: Richard
authors: R
authors: Elson
authors: Martin
authors: M
authors: Day
authors: Rohini
authors: R
authors: Manuel
authors: Jayshree
authors: J
authors: Dave
authors: Nigel
authors: N
authors: Field
authors: Gauri
authors: G
authors: Godbole
authors: Timothy
authors: T
authors: Dallman
authors: Paul
authors: P
authors: Crook
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D004405:Dysentery, Bacillary / Q000188:drug therapy / Q000453:epidemiology* / Q000266:history / Q000382:microbiology*; D004739:England / Q000453:epidemiology; D016680:Genome, Bacterial; D049674:History, 21st Century; D018451:Homosexuality, Male; D006801:Humans; D018942:Macrolides / Q000494:pharmacology*; D008297:Male; D008826:Microbial Sensitivity Tests; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide; D012764:Shigella sonnei / Q000145:classification / Q000187:drug effects* / Q000235:genetics*; D000073336:Whole Genome Sequencing; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; D001618:beta-Lactamases
keywords: ESBL; ESBL producers; England; MSM; STIs; Shigella; Shigella sonnei; antimicrobial resistance; bacteria; bacterial infections; extended-spectrum beta-lactamase; men who have sex with men; outbreaks; sexually transmitted infections