title: Primary Pure Keratinising Squamous Cell Carcinoma: A Rare Malignancy with Aggressive Behaviour.
abstract: Primary well differentiated keratinising Squamous Cell Carcinoma (SCC) is a rare gall bladder malignancy accounting for 3.3% of all gall bladder carcinomas. Here we present a case of a 70-year-old female with complaints of dyspepsia and right upper quadrant pain for 3 months. Ultrasonography showed gall stones along with thickened and irregular gall bladder wall. Grossly an exophytic growth was noted involving large part of the body of gall bladder. Histological features were of well differentiated SCC with extensive keratinisation involving full thickness of the wall. No glandular component was seen. Metastasis from other primary was ruled out after thorough work-up. SCC of gall bladder has an infiltrative growth pattern and behaves aggressively. Early diagnosis plays the most important role in increasing the survival.
authors: Senior Resident, Department of Pathology, North Delhi Municipal Corporation Medical College & Hindu Rao Hospital , Delhi, India .
authors: Mansi
authors: M
authors: Chandna
authors: Medical Superintendent, Kasturba Hospital , New Delhi, India .
authors: Leela
authors: L
authors: Pant
authors: DNB Student, Department of Pathology, North Delhi Municipal Corporation Medical College & Hindu Rao Hospital , Delhi, India .
authors: Malini
authors: M
authors: Garg
authors: Senior Resident, Department of Pathology, North Delhi Municipal Corporation Medical College & Hindu Rao Hospital , Delhi, India .
authors: Garima
authors: G
authors: Singh
authors: Specialist, Department of Pathology, Hindu Rao Hospital , Delhi, India .
authors: Sompal
authors: S
authors: Singh
keywords: Adenosquamous; Chronic cholecystitis; Gall bladder carcinoma