title: Dynamics of West Nile virus evolution in mosquito vectors.
abstract: West Nile virus remains the most common cause of arboviral encephalitis in North America. Since it was introduced, it has undergone adaptive genetic change as it spread throughout the continent. The WNV transmission cycle is relatively tractable in the laboratory. Thus the virus serves as a convenient model system for studying the population biology of mosquito-borne flaviviruses as they undergo transmission to and from mosquitoes and vertebrates. This review summarizes the current knowledge regarding the population dynamics of this virus within mosquito vectors.
authors: Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. Electronic address: nathan.grubaugh@yahoo.com.
authors: Nathan D
authors: ND
authors: Grubaugh
authors: Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA. Electronic address: gregory.ebel@colostate.edu.
authors: Gregory D
authors: GD
authors: Ebel
mesh_terms: D000220:Adaptation, Biological; D000818:Animals; D000072138:Mosquito Vectors / Q000821:virology*; D009656:North America; D011157:Population Dynamics; D014902:West Nile virus / Q000235:genetics* / Q000254:growth & development*