title: Investigating the Genetic Basis of Social Conformity: The Role of the Dopamine Receptor 3 (DRD3) Gene.
abstract: BACKGROUND
  People often change their opinions or behavior to match the responses of others, a phenomenon known as social conformity. Conforming behavior varies substantially across individuals. However, little is known about the genetic basis underlying individual differences in social conformity. A recent study demonstrated an association between enhanced dopaminergic function and increased conforming behavior. Given the effect of the dopamine receptor 3 gene (DRD3) Ser9Gly polymorphism (rs6280) on dopamine release in the striatum, this study investigated to what extent this polymorphism affects conforming behavior.
  
  
  METHODS
  We categorized Han Chinese individuals according to the polymorphism and tested them with a facial-attractiveness rating task.
  
  
  RESULTS
  We found that individuals with a greater number of the Gly alleles, which are related to an increased dopamine release in the striatum, were more susceptible to social influence and more likely to change their ratings to match those of other people.
  
  
  CONCLUSIONS
  This finding demonstrates the importance of DRD3 Ser9Gly as a genetic basis for social conformity and in predicting individual differences in social learning.
authors: Center for Brain and Cognitive Sciences, Peking University, Beijing, China.
authors: Chunli
authors: C
authors: Zhao
authors: Jinting
authors: J
authors: Liu
authors: Pingyuan
authors: P
authors: Gong
authors: Jie
authors: J
authors: Hu
authors: Xiaolin
authors: X
authors: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000483:Alleles; D044466:Asian People / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D050637:Receptors, Dopamine D3 / Q000235:genetics*; D012919:Social Behavior; D012925:Social Conformity; D055815:Young Adult
chemical_list: C493593:DRD3 protein, human; D050637:Receptors, Dopamine D3