title: Prevalence and Correlates of Peripheral Arterial Disease in Nigerians with Type 2 Diabetes.
abstract: Background. Peripheral arterial disease (PAD) is a major risk factor for nonhealing foot ulcers in people with diabetes. A number of traditional risk factors have been reported to be associated with PAD; however, there may be a need to consider nontraditional risk factors especially in some vulnerable populations. This study determined the prevalence and risk factors associated with PAD in diabetics.Methods. One hundred and fifty type 2 diabetics and an equal number of age- and sex-matched apparently healthy controls were studied. Assessment of PAD was made using history, palpation of lower limb vessels, and measurement of ankle-brachial index (ABI). Statistically significant differences between categorical and continuous variables were determined using Chi square (χ2) and Studentt-tests, respectively. Regression analysis was done to determine the associated risk factors for PAD.Results. Prevalence of PAD using ABI was 22.0% and 8.0% among diabetic and nondiabetic populations, respectively. Peripheral arterial disease was associated with age, male gender, waist circumference, and high-sensitivity C-reactive protein.Conclusion. This study highlights the high prevalence of PAD in people with type 2 diabetes mellitus and in apparently healthy controls; age, male gender, abdominal obesity, and high hs-CRP values were the associated risk factors.
authors: Department of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors: D O
authors: 0000-0002-9659-2658
authors: DO
authors: Soyoye
authors: Department of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors: R T
authors: RT
authors: Ikem
authors: Department of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors: B A
authors: 0000-0002-8242-3968
authors: BA
authors: Kolawole
authors: Department of Surgery, Ekiti State University, Ado-Ekiti, Nigeria.
authors: K S
authors: KS
authors: Oluwadiya
authors: Department of Haematology and Immunology, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors: R A
authors: RA
authors: Bolarinwa
authors: Department of Medicine, Federal Medical Centre, Lokoja, Nigeria.
authors: O J
authors: OJ
authors: Adebayo