title: Efficacy of Adenine in the Treatment of Leukopenia and Neutropenia Associated with an Overdose of Antipsychotics or Discontinuation of Lithium Carbonate Administration: Three Case Studies.
abstract: Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients with leukopenia and neutropenia caused by an antipsychotic overdose or discontinuation of lithium carbonate, in whom adenine administration ameliorated the white blood cell and neutrophil counts. The progress of patients suggests that adenine is effective in cases of leukopenia and neutropenia associated with lithium carbonate discontinuation and an antipsychotic overdose.
authors: Department of Pharmacy, Hospital Bando, Bando, Japan.
authors: Takashi
authors: T
authors: Tomita
authors: Department of Pharmacy, Hospital Bando, Bando, Japan.
authors: Hidekazu
authors: H
authors: Goto
authors: Faculty of Pharmacy, Iwaki Meisei University, Iwaki, Japan.
authors: Kenji
authors: K
authors: Sumiya
authors: Department of Internal Medicine, Hospital Bando, Bando, Japan.
authors: Tadashi
authors: T
authors: Yoshida
authors: Department of Psychiatry, Hospital Bando, Bando, Japan.
authors: Katsuya
authors: K
authors: Tanaka
authors: Department of Pharmacy, Hospital Bando, Bando, Japan.|Faculty of Health Sciences, Tsukuba International University, Tsuchiura, Japan.
authors: Yukinao
authors: Y
authors: Kohda
keywords: Adenine; Antipsychotic agents; Leukopenia; Lithium carbonate; Neutropenia