title: What is the effect of pill burden on adherence to HIV antiretroviral therapy?
abstract: Antiretroviral therapy (ART) is a combination treatment involving three or more antiretroviral agents for patients with HIV. ART has reduced HIV-related morbidity and mortality via single-tablet or multiple-tablet regimens. Single-tablet regimens, with their lower pill burdens, have demonstrated higher adherence rates, improved viral suppression, and reduced resource use compared with multiple-tablet regimens. In addition, select newer ARTs do not require the high levels of adherence for viral load suppression required by older ART formulations.
authors: S. Scott Sutton is a professor in the Department of Clinical Pharmacy and Outcomes Sciences in the South Carolina College of Pharmacy at the University of South Carolina in Columbia, S.C. Divya Ahuja is an associate professor in the University of South Carolina School of Medicine. Joseph Magagnoli is a statistician in the Dorn Research Institute at the Veterans Affairs Medical Center in Columbia, S.C. The authors have disclosed no potential conflicts of interest, financial or otherwise.
authors: S Scott
authors: SS
authors: Sutton
authors: Divya
authors: D
authors: Ahuja
authors: Joseph
authors: J
authors: Magagnoli
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D019562:Viral Load
chemical_list: D019380:Anti-HIV Agents