title: On keeping the right ER size.
abstract: The endoplasmic reticulum (ER) is the largest membrane-bound organelle in cells, and its size needs to be carefully controlled. Downsizing the ER by autophagy is now shown to involve Sec62, a protein that also helps to build up the organelle. This link suggests a molecular switch for ER size control.
authors: CellNetworks Cluster of Excellence and Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Heidelberg University, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany.
authors: Sebastian
authors: S
authors: Schuck
mesh_terms: D000818:Animals; D001343:Autophagy / Q000502:physiology*; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006801:Humans; D026901:Membrane Transport Proteins / Q000378:metabolism*; D015388:Organelles / Q000378:metabolism*; D021381:Protein Transport
chemical_list: D026901:Membrane Transport Proteins; C103676:SEC62 protein, human