title: Over or under: hydride attack at the metal versus the coordinated nitrosyl ligand in ferric nitrosyl porphyrins.
abstract: Hydride attack at a ferric heme-NO to give an Fe-HNO intermediate is a key step in the global N-cycle. We demonstrate differential reactivity when six- and five-coordinate ferric heme-NO models react with hydride. Although Fe-HNO formation is thermodynamically favored from this reaction, Fe-H formation is kinetically favored for the 5C case.
authors: Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, USA. grichteraddo@ou.edu.
authors: E G
authors: EG
authors: Abucayon
authors: Department of Biomedical Engineering, Chemistry and Biological Sciences, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, New Jersey 07030, USA. yong.zhang@stevens.edu.
authors: R L
authors: RL
authors: Khade
authors: Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, USA. grichteraddo@ou.edu.
authors: D R
authors: DR
authors: Powell
authors: Department of Chemistry, Southern Illinois University Edwardsville, Edwardsville, Illinois 62025, USA.
authors: M J
authors: MJ
authors: Shaw
authors: Department of Biomedical Engineering, Chemistry and Biological Sciences, Stevens Institute of Technology, Castle Point on Hudson, Hoboken, New Jersey 07030, USA. yong.zhang@stevens.edu.
authors: Y
authors: Y
authors: Zhang
authors: Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, USA. grichteraddo@ou.edu.
authors: G B
authors: GB
authors: Richter-Addo