title: Designing for cleanability: The effects of material, surface roughness, and the presence of blood test soil and bacteria on devices.
abstract: Cleaning reusable medical devices removes organic and inorganic soil, which allows for effective disinfection and sterilization. However, it is not always clear what variables to consider when validating cleaning. This study compared the ability of 3 different cleaning agents (ie, water, alcohol, and bleach) to remove bacteria (ie, vegetative and spores) and artificial blood test soil from 2 common device materials: polypropylene and ultra-high-molecular-weight polyethylene. There was a complex interaction between bacteria, soil, and surface roughness.
authors: Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD.
authors: Elizabeth A
authors: EA
authors: Gonzalez
authors: Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD. Electronic address: Poulomi.Nandy@fda.hhs.gov.
authors: Poulomi
authors: P
authors: Nandy
authors: Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD.
authors: Anne D
authors: AD
authors: Lucas
authors: Laboratory of Microbiology and Infection Control, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD.
authors: Victoria M
authors: VM
authors: Hitchins
mesh_terms: D001419:Bacteria / Q000302:isolation & purification*; D003666:Decontamination / Q000379:methods; D004203:Disinfection / Q000379:methods; D004866:Equipment Contamination; D004864:Equipment and Supplies; D006403:Hematologic Tests; D006801:Humans; D013499:Surface Properties
keywords: Bacterial adhesion; Reprocessing; Reusable medical device; Synthetic soil