title: Solid contact ion sensor with conducting polymer layer copolymerized with the ion-selective membrane for determination of calcium in blood serum.
abstract: A new solid contact ion selective electrode with intermediate conducting polymer (CP) layer formed by electropolymerization on a gold electrode of a bifunctional monomer, n-phenyl-ethylenediamine-methacrylamide (NPEDMA), which contains a methacrylamide group attached to aniline, is presented. The conducting polymer was studied by means of optical spectroscopy, cyclic voltammetry and potentiometric measurements. Ca2+-ion-selective membrane based on acrylated urethane polymer was shown to co-polymerize with the CP forming highly adhesive boundary that prevents formation of water layers between the CP and membrane, thus enhancing the stability and life-time of the sensor. The designed ion-selective electrode was successfully used for determination of total calcium ion concentration in blood serum samples.
authors: BioMEMS Group, Instituto de Microelectrónica de Barcelona, Centro Nacional de Microelectrónica (CSIC), Campus U.A.B., 08193, Bellaterra, Barcelona, Spain; Lab. Artificial Sensors Syst., ITMO University, Kronverskiy pr. 49, 197101, St. Petersburg, Russia.
authors: Natalia
authors: N
authors: Abramova
authors: Department of Chemical, Biological and Environmental Engineering, Escola d'Enginyeria, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain.
authors: Javier
authors: J
authors: Moral-Vico
authors: BioMEMS Group, Instituto de Microelectrónica de Barcelona, Centro Nacional de Microelectrónica (CSIC), Campus U.A.B., 08193, Bellaterra, Barcelona, Spain.
authors: Jordi
authors: J
authors: Soley
authors: BioMEMS Group, Instituto de Microelectrónica de Barcelona, Centro Nacional de Microelectrónica (CSIC), Campus U.A.B., 08193, Bellaterra, Barcelona, Spain.
authors: Cristina
authors: C
authors: Ocaña
authors: BioMEMS Group, Instituto de Microelectrónica de Barcelona, Centro Nacional de Microelectrónica (CSIC), Campus U.A.B., 08193, Bellaterra, Barcelona, Spain. Electronic address: andrei.bratov@imb-cnm.csic.es.
authors: Andrey
authors: A
authors: Bratov
mesh_terms: D002118:Calcium / Q000097:blood*; D006801:Humans; D017736:Ion-Selective Electrodes; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers; D002118:Calcium
keywords: Blood serum; Calcium ions; Conducting polymer; Solid-contact ion selective electrode