title: Possible influence of the environmental pollutant bisphenol A on the cardiometabolic risk factors.
abstract: Bisphenol A (BPA) is a ubiquitous environmental pollutant which is often associated with various health issues. In this study 103 healthy female volunteers in reproductive age from Serbian north province Vojvodina were enrolled and examined for the BPA exposure in the urine samples after 12 h of fasting. BPA was found in 35.92 % (37/103) of subjects. Statistically significant increment in waist circumference (p = 0.045) and waist-to-height ratio (p = 0.037) was observed among the BPA positive women in comparison with the women who had the same energetic balance and had not been exposed to BPA. Linear correlation was obtained between the BPA concentration in urine samples and body mass index (r2= 0.35, p = 0.003) waist circumference (r2= 0.21, p = 0.02) and waist-to-height ratio (r2= 0.25, p = 0.01) among the obese. High energetic intake and reduced physical activity additionally pronounced BPA positive association with obesity. No statistically significant difference was observed in triglycerides, HDL and LDL cholesterol levels between the BPA exposed and BPA non-exposed female volunteers.
authors: a Faculty of Medicine, Department of Pharmacy , University of Novi Sad , Novi Sad , Serbia.
authors: Nataša
authors: N
authors: Milošević
authors: b Faculty of Medicine , University of Novi Sad , Novi Sad , Serbia.
authors: Vladimir
authors: V
authors: Jakšić
authors: a Faculty of Medicine, Department of Pharmacy , University of Novi Sad , Novi Sad , Serbia.
authors: Jan
authors: J
authors: Sudji
authors: c Faculty of Medicine , Clinical Center of Vojvodina, Emergency Center, University of Novi Sad , Novi Sad , Serbia.
authors: Bojan
authors: B
authors: Vuković
authors: d Faculty of Medicine, Clinic for Endocrinology, Diabetes and Metabolic Diseases , Clinical Center of Vojvodina, University of Novi Sad , Novi Sad , Serbia.
authors: Tijana
authors: T
authors: Ičin
authors: a Faculty of Medicine, Department of Pharmacy , University of Novi Sad , Novi Sad , Serbia.
authors: Nataša
authors: N
authors: Milić
authors: d Faculty of Medicine, Clinic for Endocrinology, Diabetes and Metabolic Diseases , Clinical Center of Vojvodina, University of Novi Sad , Novi Sad , Serbia.
authors: Milica
authors: M
authors: Medić Stojanoska
mesh_terms: D000293:Adolescent; D000328:Adult; D001559:Benzhydryl Compounds / Q000633:toxicity / Q000652:urine*; D003430:Cross-Sectional Studies; D004781:Environmental Exposure; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000633:toxicity / Q000652:urine*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000139:chemically induced / Q000453:epidemiology*; D056128:Obesity, Abdominal / Q000139:chemically induced / Q000453:epidemiology; D010636:Phenols / Q000633:toxicity / Q000652:urine*; D012307:Risk Factors; D055771:Serbia / Q000453:epidemiology; D055815:Young Adult; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004785:Environmental Pollutants; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Bisphenol A; cardiometabolic risk factors; emerging substances; endocrine disrupting chemicals; obesity