title: Correlations between impulsiveness and biochemical parameters in women with polycystic ovary syndrome.
abstract: OBJECTIVE
  The aim of this study was to investigate the relationship between anger, impulsiveness, and biochemical parameters (testosterone, insulin, insulin resistance) in women with polycystic ovary syndrome.
  
  
  METHODS
  We recruited 84 women diagnosed with polycystic ovary syndrome according to the Rotterdam diagnostic criteria. Psychiatric interviews were performed using the Structured Clinical Interview for DSM-IV Axis I Disorders. The Barratt Impulsiveness Scale and the State Trait Anger Expression Inventory were also administered to each participant. Lastly, the women's biochemical parameters, which included total testosterone, free androgen index, dehydroepiandrosterone sulfate, insulin and insulin resistance, thyroid functions, and prolactin, were measured.
  
  
  RESULTS
  A statistically significant correlation was found between participants' increasing total testosterone levels and total impulsiveness scores, and their increasing free androgen index levels and motor and non-planning-related impulsiveness (r=0.24, p=0.027; r=0.27, p=0.015; and r=0.26, p=0.017, respectively). High insulin and insulin resistance levels were associated with high non-planning-related impulsiveness scores (r=0.26, p=0.018; and r=0.26, p=0.019). Lastly, high trait anger and anger expression scores were related to high total testosterone and insulin and insulin resistance levels.
  
  
  CONCLUSIONS
  Androgens and glucose dysregulation seemingly affect anger expression as well as the attentional, motor, and non-planning-related impulsiveness of women with polycystic ovary syndrome.
authors: Psychiatry Department, Sakarya University, Sakarya Training and Research Hospital, Turkey.
authors: Esra
authors: E
authors: Özdil Demiryürek
authors: Psychiatry Department, Bolu Mental and Psychiatric Disease Hospital, Turkey. Electronic address: md.atillatekin@gmail.com.
authors: Atilla
authors: A
authors: Tekin
authors: Psychiatry Department, Şişli Hamidiye Etfal Training and Research Hospital, Turkey.
authors: Engin
authors: E
authors: Çakmak
authors: Gynaecology and Obstetrics Department, Şişli Hamidiye Etfal Training and Research Hospital, Turkey.
authors: Osman
authors: O
authors: Temizkan
authors: Psychiatry Department, Şişli Hamidiye Etfal Training and Research Hospital, Turkey.
authors: Oğuz
authors: O
authors: Karamustafalıoğlu
authors: Gynaecology and Obstetrics Department, Şişli Hamidiye Etfal Training and Research Hospital, Turkey.
authors: Sibel
authors: S
authors: Gökova
authors: Neurology Department, Sakarya University, Sakarya Training and Research Hospital, Turkey.
authors: Enes
authors: E
authors: Demiryürek
mesh_terms: D000293:Adolescent; D000328:Adult; D000728:Androgens / Q000097:blood; D015897:Comorbidity; D003430:Cross-Sectional Studies; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood; D003865:Major Depressive Disorder / Q000453:epidemiology*; D019263:Dysthymic Disorder / Q000453:epidemiology*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D006946:Hyperinsulinism / Q000209:etiology*; D007333:Insulin Resistance; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology*; D000072861:Phobia, Social / Q000453:epidemiology*; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology / Q000378:metabolism / Q000503:physiopathology / Q000523:psychology*; D011388:Prolactin / Q000097:blood; D011569:Psychiatric Status Rating Scales; D013739:Testosterone / Q000097:blood; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000728:Androgens; D013739:Testosterone; D019314:Dehydroepiandrosterone Sulfate; D011388:Prolactin
keywords: Androgen; Anger; Impulsiveness; Insulin; Polycystic ovary syndrome