title: Dipeptidyl Peptidase-4, Wound Healing, Scarring, and Fibrosis.
abstract: Scarring and fibrosis are an enormous public health concern, resulting in excessive morbidity and mortality in addition to countless lost health care dollars. Recent advances in cell and developmental biology promise a better understanding of scarring and fibrosis and may translate to new clinical therapies.
authors: Stanford, Calif.; and Honolulu, Hawai'i.|From the Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine; the Institute for Stem Cell Biology and Regenerative Medicine, Stanford University; and the Department of Surgery, John A. Burns School of Medicine, University of Hawai'i.
authors: Michael S
authors: MS
authors: Hu
authors: Stanford, Calif.; and Honolulu, Hawai'i.|From the Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine; the Institute for Stem Cell Biology and Regenerative Medicine, Stanford University; and the Department of Surgery, John A. Burns School of Medicine, University of Hawai'i.
authors: Michael T
authors: MT
authors: Longaker
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000201:enzymology / Q000473:pathology; D002921:Cicatrix / Q000503:physiopathology* / Q000517:prevention & control; D003238:Connective Tissue / Q000378:metabolism; D018819:Dipeptidyl Peptidase 4 / Q000502:physiology*; D054873:Dipeptidyl-Peptidase IV Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D005347:Fibroblasts / Q000201:enzymology / Q000473:pathology*; D005355:Fibrosis / Q000201:enzymology / Q000517:prevention & control; D018398:Homeodomain Proteins / Q000235:genetics / Q000502:physiology; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology / Q000627:therapeutic use; D007249:Inflammation / Q000503:physiopathology / Q000517:prevention & control; D007674:Kidney Diseases / Q000201:enzymology / Q000473:pathology; D008103:Liver Cirrhosis / Q000201:enzymology / Q000473:pathology; D051379:Mice; D008822:Mice, Transgenic; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology*
chemical_list: D054873:Dipeptidyl-Peptidase IV Inhibitors; C080330:En1 protein, mouse; D018398:Homeodomain Proteins; D007004:Hypoglycemic Agents; C042807:DPP4 protein, human; D018819:Dipeptidyl Peptidase 4