title: Common Inflammatory Disorders and Neoplasia of the Ileal Pouch: A Review of Histopathology.
abstract: Ileal pouch-anal anastomosis (IPAA) is the standard restorative procedure after proctocolectomy in patients with ulcerative colitis (UC) who require colectomy. The ileal pouch is susceptible to a variety of insults including mechanical injury, ischemia, fecal stasis, and infectious agents. In addition, the development of recurrent and idiopathic inflammatory bowel disease and neoplasia may occur in the ileal pouch. Although clinical, endoscopic, and radiographic examination can diagnose many ileal pouch diseases, histologic examination plays an essential role in diagnosis and management, particularly in cases with antibiotic refractory chronic pouchitis and pouch neoplasia.
authors: Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
authors: David Hernandez
authors: DH
authors: Gonzalo
authors: Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
authors: Amy L
authors: AL
authors: Collinsworth
authors: Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
authors: Xiuli
authors: X
authors: Liu
keywords: Diagnosis; Histopathology; Ileal pouch; Inflammatory disorder; Neoplasia; Pouchitis; Ulcerative colitis