title: Orbital Cellulitis with Endogenous Panophthalmitis Caused by Methicillin-Sensitive Staphylococcus aureus in Pregnancy.
abstract: Orbital cellulitis along with panophthalmitis is uncommon. The causes are usually trauma-related or endogenous. The prognosis in terms of globe salvage is very poor, with most cases usually requiring enucleation or evisceration of the affected eye. Immunosuppression in some form is usually present, which accounts for the aggressive course of the infection. In this communication, we report on a case in a 25-year-old female, who in the second trimester of pregnancy had developed orbital cellulitis and panophthalmitis caused by methicillin-sensitive Staphylococcus aureus (MSSA), with the primary source of infection being cellulitis on her forearm following intravenous therapy for severe anemia. Despite intensive intravenous and topical antibiotics, she required an evisceration of the eye. However, the pregnancy continued uneventfully with the delivery of a full-term, healthy infant. Bacteremia, although rare in pregnancy, can cause endogenous panophthalmitis and orbital cellulitis, especially in a background of immunosuppresssion.
authors: Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital Sion.
authors: Simranjeet
authors: S
authors: Aulakh
authors: Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital Sion.|Advanced Eye Hospital & Institute, Sanpada, Maharashtra.
authors: Akshay
authors: A
authors: Gopinathan Nair
authors: Green Templeton College, University of Oxford.
authors: Rahul
authors: R
authors: Gandhi
authors: Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital Sion.
authors: Amit
authors: A
authors: H Palkar
authors: Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital Sion.
authors: Mihir
authors: M
authors: G Trivedi
authors: Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital Sion.
authors: Nayana
authors: N
authors: A Potdar
authors: Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital Sion.
authors: Chhaya
authors: C
authors: A Shinde
mesh_terms: D000328:Adult; D000740:Anemia / Q000150:complications / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D055499:Catheter-Related Infections / Q000150:complications; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D008712:Methicillin / Q000494:pharmacology; D054517:Orbital Cellulitis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010202:Panophthalmitis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013203:Staphylococcal Infections / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D008712:Methicillin
keywords: MSSA; bacteremia; orbital cellulitis; panophthalmitis; pregnancy