title: A Scoring Instrument to Predict the Survival Prognoses of Patients with Metastatic Epidural Spinal Cord Compression from Gynecological Malignancies.
abstract: To design a scoring instrument for rating overall survival (OS) of patients with metastatic epidural sinal cord compression (MESCC) from gynecological malignancies.
  
  
  
  In 22 patients treated with radiotherapy alone for MESCC from gynecological malignancies, ten factors were analyzed for effects on OS. Factors significantly associated with OS on multivariate analysis were included in a scoring instrument.
  
  
  
  On multivariate analyses, no visceral metastases (p=0.004) and affection of 1-2 vertebrae (p=0.012) were significant. Scoring points for each factor were 0 or 1, depending on OS rates. After summing, scores of 0 (n=6), 1 (n=9) or 2 points (n=9) were obtained. OS rates were 0%, 78% and 100%, respectively, at 3 months and 0%, 33% and 86%, respectively, at 6 months (p<0.001).
  
  
  
  An instrument was developed for estimating the lifespan of patients with MESCC from gynecological malignancies. This instrument can support physicians when picking an individual treatment.
authors: Department of Radiation Oncology, University of Lübeck, Lübeck, Germany.|Medical Practice of Radiotherapy and Radiation Oncology, Hannover, Germany.
authors: Stefan
authors: S
authors: Janssen
authors: Department of Radiation Oncology, University Medical Center Eppendorf, Hamburg, Germany.
authors: Amira
authors: A
authors: Bajrovic
authors: Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.
authors: Steven E
authors: SE
authors: Schild
authors: Department of Radiation Oncology, University of Lübeck, Lübeck, Germany rades.dirk@gmx.net.
authors: Dirk
authors: D
authors: Rades
mesh_terms: D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D013117:Spinal Cord Compression / Q000209:etiology*; D013125:Spinal Neoplasms / Q000556:secondary*; D015996:Survival Rate
keywords: Gynecological cancer; MESCC; overall survival; radiotherapy; scoring instrument