title: Time Trends in Lifetime Incidence Rates of First-Time Diagnosed Bipolar and Depressive Disorders Across 16 Years in Danish Psychiatric Hospitals: A Nationwide Study.
abstract: OBJECTIVE
  There is conflicting evidence as to whether or not the incidences of affective disorders are on the rise. The aim of the present study was to identify time trends across 16 years in the incidences of affective disorders in a nationwide sample.
  
  
  METHODS
  Using the Danish Psychiatric Central Research Registry, age- and sex-adjusted incidence rates of diagnosed affective disorders in Danish psychiatric hospitals using ICD-10 classification were calculated per 100,000 person-years for the population aged 4-65 years during the period 1995-2010.
  
  
  RESULTS
  Incidence rates of diagnosed bipolar disorder increased from 11.5 to 24.5, and there was an increase from 86.2 to 189.7 per 100,000 person-years for depression. Time trends were most pronounced for individuals up to 29 years of age. A sizeable part of the increase in incidence rates could be attributed to an increase in the total number of persons diagnosed in psychiatry.
  
  
  CONCLUSIONS
  Time trends in incidence rates showed an increase for bipolar disorder and depressive disorders across 16 years, but found that some of the observed increase in incidence rates was related to a more widespread trend in Danish society of seeking and receiving psychiatric assistance.
authors: Research Unit for Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark.
authors: Christina Mohr
authors: CM
authors: Jensen
authors: Department of Child and Adolescent Psychiatry, Neumuensterallee 9, University of Zurich, CH-8032 Zurich, Switzerland. hc.steinhausen@kjpd.uzh.ch.|Research Unit for Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark.|Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland.|Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland.
authors: Hans-Christoph
authors: HC
authors: Steinhausen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D003718:Denmark / Q000453:epidemiology; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006778:Hospitals, Psychiatric / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D012042:Registries / Q000706:statistics & numerical data*; D013997:Time Factors; D055815:Young Adult