title: Synthesis of macromolecular systems via lipase catalyzed biocatalytic reactions: applications and future perspectives.
abstract: Enzymes, being remarkable catalysts, are capable of accepting a wide range of complex molecules as substrates and catalyze a variety of reactions with a high degree of chemo-, stereo- and regioselectivity in most of the reactions. Biocatalysis can be used in both simple and complex chemical transformations without the need for tedious protection and deprotection chemistry that is very common in traditional organic synthesis. This current review highlights the applicability of one class of biocatalysts viz."lipases" in synthetic transformations, the resolution of pharmaceutically important small molecules including polyphenols, amides, nucleosides and their precursors, the development of macromolecular systems (and their applications as drug/gene carriers), flame retardants, polymeric antioxidants and nanocrystalline solar cells, etc.
authors: Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi 110 007, India. virparmar@gmail.com vparmar@inads.org parmar@cuh.ac.in amit.sep85@gmail.com.
authors: Amit
authors: A
authors: Kumar
authors: Abdullah
authors: A
authors: Khan
authors: Shashwat
authors: S
authors: Malhotra
authors: Ravi
authors: R
authors: Mosurkal
authors: Ashish
authors: A
authors: Dhawan
authors: Mukesh K
authors: MK
authors: Pandey
authors: Brajendra K
authors: BK
authors: Singh
authors: Rajesh
authors: R
authors: Kumar
authors: Ashok K
authors: AK
authors: Prasad
authors: Sunil K
authors: SK
authors: Sharma
authors: Lynne A
authors: LA
authors: Samuelson
authors: Ashok L
authors: AL
authors: Cholli
authors: Christophe
authors: C
authors: Len
authors: Nigel G J
authors: NG
authors: Richards
authors: Jayant
authors: J
authors: Kumar
authors: Rainer
authors: R
authors: Haag
authors: Arthur C
authors: AC
authors: Watterson
authors: Virinder S
authors: VS
authors: Parmar
mesh_terms: D000577:Amides / Q000138:chemical synthesis; D000975:Antioxidants / Q000138:chemical synthesis; D055162:Biocatalysis; D004337:Drug Carriers / Q000138:chemical synthesis; D005411:Flame Retardants / Q000138:chemical synthesis; D006801:Humans; D008049:Lipase / Q000737:chemistry*; D046911:Macromolecular Substances / Q000138:chemical synthesis*; D049329:Nanostructures / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis; D059808:Polyphenols / Q000138:chemical synthesis; D012993:Solar Energy
chemical_list: D000577:Amides; D000975:Antioxidants; D004337:Drug Carriers; D005411:Flame Retardants; D046911:Macromolecular Substances; D009705:Nucleosides; D059808:Polyphenols; D008049:Lipase