title: Comparative assessment of selected intraoral microorganisms – potential factors for peri-surgical management complications
abstract: In this research, a comparative analysis of results of investigations involving different human populations, in terms of a relation between the oral cavity health and the species composition of mouth microbiota is reported. The purpose of this analysis was to identify and assess microorganisms that could cause health complications in patients with neoplasm requiring dental problem-related surgical management. The patients with the oral cancer surgically treated and those without neoplasm were assessed for their oral health: status of teeth, gingiva, periodontium, and occurrence of inflammatory processes. From each patient, microorganisms isolated of periodontium, dental plaque, and dental pocket swabs were identified in wet and stained microscopic preparations; standard microbiology in vitro techniques were also applied to determine the fungal and bacterial strains. The comparative analysis of results of direct microscopic examinations and in vitro cultures assessment indicated significant differences in prevalences of fungi, parasitic oral protozoans and bacteriae in particular patient’s groups. Yeast-like fungi belonging to Candida genus, mostly of C. albicans group, were identified in 93.75% patients with the oral cancer, while in 25% of individuals assessed without neoplasm. E. gingivalis amoebae were only found in 12.5% patients with the serious disease; no trichomonads were detected in all patients analyzed. Among bacteria species, potentially pathogenic Enterobacteriaceae were found in the patients with oral cancer. The pronounced shift in the microbiota species composition in the patients who needed prolonged treatment due to oral cavity cancer, compared to other generally healthy persons has been showed in this analysis.
authors: Clinic of Cranio-Maxillo-Facial and Oral Surgery and Implantology, Medical University of Warsaw, ul. Lindleya 4, 02-005 Warsaw, Poland
authors: Paweł J.
authors: PE
authors: Zawadzki
authors: Department of Pharmaceutical Microbiology, Medical University of Warsaw, ul. Oczki 3, 02-007 Warsaw, Poland
authors: Bohdan
authors: B
authors: Starościak
authors: Department of Orthodontics, Medical University of Warsaw, ul. Nowogrodzka 59, 02-005 Warsaw, Poland
authors: Konrad
authors: K
authors: Perkowski
authors: Department of Medical Biology, Medical University of Warsaw, ul. Nowogrodzka73, 02-018 Warsaw, Poland|Department of Disaster Medicine, Medical University of Warsaw, ul.Żwirki i Wigury 81, 02-091Warsaw, Poland
authors: Wanda
authors: W
authors: Baltaza
authors: Department of Medical Biology, Medical University of Warsaw, ul. Nowogrodzka73, 02-018 Warsaw, Poland
authors: Marcin
authors: M
authors: Padzik
authors: Department of Medical Biology, Medical University of Warsaw, ul. Nowogrodzka73, 02-018 Warsaw, Poland
authors: Krzysztof
authors: K
authors: Pionkowski
authors: Department of Medical Biology, Medical University of Warsaw, ul. Nowogrodzka73, 02-018 Warsaw, Poland
authors: Lidia
authors: L
authors: Chomicz
mesh_terms: D000368:Aged; D001419:Bacteria / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification*; D004747:Entamoeba / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D009059:Mouth Diseases / Q000601:surgery