title: A macromolecular cyclometalated gold(iii) amphiphile displays long-lived emissive excited state in water: self-assembly and in vitro photo-toxicity.
abstract: We report an amphiphilic macromolecule containing a cyclometalated gold(iii) complex that self-assembles into nano-sized micelles and also displays a long-lived emissive triplet excited state with a lifetime of 84 μs in degassed water. This amphiphilic AuIIIcomplex exhibits good biocompatibility and activity towards in vitro photo-toxicity, as well as enhanced permeability and retention effects in vivo.
authors: State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. cmche@hku.hk.
authors: Feng
authors: F
authors: Wang
authors: Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry (TIPC), Chinese Academy of Sciences, Beijing 100190, China.
authors: Minhuan
authors: M
authors: Lan
authors: State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. cmche@hku.hk.
authors: Wai-Pong
authors: WP
authors: To
authors: State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. cmche@hku.hk.
authors: Kai
authors: K
authors: Li
authors: State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. cmche@hku.hk.
authors: Chun-Nam
authors: CN
authors: Lok
authors: Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry (TIPC), Chinese Academy of Sciences, Beijing 100190, China.
authors: Pengfei
authors: P
authors: Wang
authors: State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. cmche@hku.hk and HKU-Shenzhen Institute of Research and Innovation, Shenzhen 518053, China.
authors: Chi-Ming
authors: CM
authors: Che