title: Predictive Value of HRT Stereometric Parameters and Blue-on-Yellow Perimetry Global Indices in Glaucoma-suspected Subjects.
abstract: To determine subtle changes of Heidelberg retina tomography (HRT) stereometric parameters and blue-on-yellow (B/Y) perimetry global indices for the early diagnosis of glaucoma in suspected subjects.
  
  
  
  Cross-sectional data on 174 eyes of 87 subjects from a larger cohort, attending the Glaucoma Department of the "G. Gennimatas" General Hospital of Athens from January 2004 to February 2014, were used in the study. Subjects were assigned to 3 groups: (a) "normals" not requiring treatment throughout the study (group 1), (b) suspects who developed glaucoma and required treatment during the study (group 2), and (c) patients with incipient glaucoma (group 3). Specific HRT and B/Y perimetry variables were compared among the 3 groups.
  
  
  
  Significant differences were established for the following HRT parameters: "reference height" differed significantly between groups 1 and 2 and groups 1 and 3; "cup shape measure" differed significantly between groups 1 and 2 and groups 2 and 3. B/Y perimetry global index "mean deviation" significantly distinguished group 2 from groups 1 and 3.
  
  
  
  The results of the present study suggest the predictive value of the HRT stereometric parameters "reference height" and "cup shape measure" and of the B/Y perimetry global index "mean deviation" in glaucoma-suspected subjects; further corroboration through longitudinal studies is warranted.
authors: *First Division of Ophthalmology, Faculty of Medicine, National and Kapodistrian University of Athens, Athens †Vardinoyiannion Eye Institute of Crete, Faculty of Medicine, University of Crete, Heraklion Crete, Greece.
authors: Konstantinos
authors: K
authors: Rallis
authors: George D
authors: GD
authors: Kymionis
authors: Ilias
authors: I
authors: Georgalas
authors: Marilita M
authors: MM
authors: Moschos
authors: Chryssanthi
authors: C
authors: Koutsandrea
authors: Michael A
authors: MA
authors: Grentzelos
authors: Dimitris
authors: D
authors: Papaconstantinou
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D005901:Glaucoma / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D011237:Predictive Value of Tests; D014054:Tomography / Q000379:methods*; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000502:physiology*