title: Silver-catalyzed nucleophilic substitution of aminals with ethyl diazoacetate: a new pathway to β-amino-α-diazoesters.
abstract: A novel silver-catalyzed nucleophilic substitution of aminals with ethyl diazoacetate producing β-amino-α-diazoesters has been developed. A series of aminals with different amino moieties and substituents were successfully incorporated in this reaction, which delivered a wide range of β-amino-α-diazocarbonyl compounds in the presence of a lower catalyst loading in 2 hours.
authors: State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China. hanmin@ustc.edu.cn.
authors: Jiawen
authors: J
authors: Li
authors: Guiping
authors: G
authors: Qin
authors: Hanmin
authors: H
authors: Huang