title: Cochlear implantation in patients with definite Meniere's disease.
abstract: The exact pathomechanism of deafening in Meniere's disease (MD) is still unknown; intoxication of hair cells and neural damage from endolymphatic hydrops is discussed. In the literature, there are only a few reports on hearing outcome of MD patients after treatment with cochlear implantation (CI) whereby especially the comparison of MD vs. non-MD patients with CI differs. In this retrospective study, results in speech understanding [Freiburger Einsilber (FES65) and Hochmair-Schulz-Moser test in quiet (HSM) and in noise (HSM + 10 dB)] of 27 implanted MD patients were collected and compared to a matched standard CI cohort. Alternative diagnoses were excluded as far as possible by re-analyzing neuroradiologic imaging. After first fitting, MD patients showed significantly better results in FES and HSM testing compared to controls. At 1-year refitting, this effect could not be seen anymore. To conclude, cochlear implantation is a safe and effective treatment for deafness in MD patients. Results in speech understanding are at least equal compared to general CI recipients. To the best of our knowledge, this retrospective study examined the largest collective of CI users deafened by MD so far.
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany. prenzler.nils@mh-hannover.de.
authors: Nils Kristian
authors: http://orcid.org/0000-0003-3721-5585
authors: NK
authors: Prenzler
authors: Zentrum für Neuroradiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Eva
authors: E
authors: Bültmann
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Alexandros
authors: A
authors: Giourgas
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Melanie
authors: M
authors: Steffens
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Rolf Benedikt
authors: RB
authors: Salcher
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Stefan
authors: S
authors: Stolle
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Anke
authors: A
authors: Lesinski-Schiedat
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Thomas
authors: T
authors: Lenarz
authors: Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1a, 30625, Hannover, Germany.
authors: Martin
authors: M
authors: Durisin
mesh_terms: D001301:Audiometry, Pure-Tone; D016022:Case-Control Studies; D019929:Cochlear Implantation; D003054:Cochlear Implants; D003638:Deafness / Q000209:etiology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000150:complications*; D008875:Middle Aged; D012189:Retrospective Studies; D013067:Speech Perception; D013701:Temporal Bone / Q000000981:diagnostic imaging
keywords: Cochlear implant; Imaging; Meniere’s disease; Outcome; Speech understanding