title: [Clinical Characteristics of 223 Chinese Patients with Hemophilia in A Medical Center of Gansu Province in China].
abstract: OBJECTIVE
  To analyze the clinical characteristics, diagonsis and treatment of patients with hemophilia in Gansu province of China.
  
  
  METHODS
  The clinical data of 223 cases of hemophilia in our center between January 2010 and May 2015 were collected and analyzed retrospectively, these 223 cases of hemophilia were from 14 cities in Gansu and neighboring provinces, including 203 cases of hemophili A (HA) and 20 cases of hemophili B (HB), among them 222 cases were male, only 1 female(HA), 177 cases were from Rural areas (79.4%).
  
  
  RESULTS
  The median age of first bleeding was 2 years old, and the average age of confirmed as hemophilia was 5.6±6.5 years, the delayed time of diagnoses of HA and HB was 2.50±4.91 and 2.07±4.76 years, respetively, among all the patients 168 caese complicated with joint hemorrhage (75.3%), 123 cases with joint deformities (55.2%). 91.6% of the patients were treated according to demand, the HBV and HCV infection rates were 1.7% and 6.2% respectively. The first-visited hospital of 86.9% patients was hospitalized below 3 grade of level, only 15.9% of these patients were considered to diagnose as hemophili.
  
  
  CONCLUSIONS
  The accurate level of diagnosis rate for hemophiliacs in Gansu province is low, the delay time of diagnosis is longer, the ratios of complicated joint hemorrhage, total accumulative joint deformity were high, HCV infection rate is also high.
authors: Department of Hematology, The First Hospital of Lanzhou University,Lanzhou 730000, Gansu Province, China.
authors: Xiao-Li
authors: XL
authors: Mou
authors: Department of Hematology, The First Hospital of Lanzhou University,Lanzhou 730000, Gansu Province, China.
authors: Yue
authors: Y
authors: Zhao
authors: Department of Hematology, The First Hospital of Lanzhou University,Lanzhou 730000, Gansu Province, China.
authors: Ze-Hua
authors: ZH
authors: Chen
authors: Department of Hematology, The First Hospital of Lanzhou University,Lanzhou 730000, Gansu Province, China.
authors: Yong-Qiang
authors: YQ
authors: Ding
authors: Department of Hematology, The First Hospital of Lanzhou University,Lanzhou 730000, Gansu Province, China.
authors: Ming
authors: M
authors: Li
authors: Department of Hematology, The First Hospital of Lanzhou University,Lanzhou 730000, Gansu Province, China.
authors: Ming-Feng
authors: MF
authors: Jia
authors: Department of Hematology, The First Hospital of Lanzhou University,Lanzhou 730000, Gansu Province, China. E-mail:xiyaming02@163.com.
authors: Ya-Ming
authors: YM
authors: Xi
mesh_terms: D002675:Child, Preschool; D002681:China; D005260:Female; D006467:Hemophilia A; D006470:Hemorrhage; D006801:Humans; D008297:Male; D012189:Retrospective Studies