title: How neuropsychology can improve the care of individual patients with epilepsy. Looking back and into the future.
abstract: Some of the roots of current clinical neuropsychology go back to the early days of epilepsy surgery. Looking back a huge number of publications have dealt with cognition in epilepsy. The major factors driving this work were questions relating to surgery, antiepileptic drugs and, more recently, also to underlying pathology. However, most factors affecting cognition in epilepsy have been discerned many years ago. The body of neuropsychological literature in this field has accumulated much knowledge, raising the question why, apart from epilepsy surgery settings, neuropsychology has still not been fully integrated in the routine care of patients with epilepsy. This review on the occasion of Seizure's 25th anniversary attempts to summarize clinically relevant diagnostic advances following a question guided, modular, and evidence-based approach. In doing so, we hope to attract the interest of readers to an exciting mode of assessment which does not only have theoretical but also practical relevance. The comorbidities of epilepsy are becoming an increasingly relevant topic. It is now widely accepted that, while epilepsy may be defined by the occurrence of epileptic seizures, these seizures represent only one of several possible sources of cognitive impairment. It is well-established that there are complex interactions between epilepsy, cognition and behavior, and that both seizures and problems with cognition or behavior may result from a common underlying pathology requiring treatment. With this review we aim to demonstrate that neuropsychology can make a highly valuable contribution to the care of individual patients by contributing to the diagnostic process and by serving as a tool for the monitoring of disease and treatment, thereby improving the quality and safety of patient care. On a national, European, and international level, first efforts are being made to homogenize diagnostics across epilepsy centers and countries in order to achieve a common language and core standards. This should improve communication within and outside the speciality, and help to generate the data required to allow the field to make further progress.
authors: University of Bonn, Department of Epileptology, Germany. Electronic address: C.Helmstaedter@uni-bonn.de.
authors: Christoph
authors: C
authors: Helmstaedter
authors: University of Bonn, Department of Epileptology, Germany.
authors: Juri-Alexander
authors: JA
authors: Witt
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D003072:Cognition Disorders / Q000209:etiology*; D004827:Epilepsy / Q000150:complications / Q000523:psychology / Q000628:therapy; D055317:Evidence-Based Practice; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009484:Neuropsychology / Q000266:history / Q000379:methods / Q000639:trends; D009493:Neurosurgery / Q000379:methods / Q000523:psychology
chemical_list: D000927:Anticonvulsants
keywords: Assessment; Cognition; Epilepsy; Etiology; Evidence based; Treatment