title: The family Rhabdoviridae: mono- and bipartite negative-sense RNA viruses with diverse genome organization and common evolutionary origins.
abstract: The family Rhabdoviridae consists of mostly enveloped, bullet-shaped or bacilliform viruses with a negative-sense, single-stranded RNA genome that infect vertebrates, invertebrates or plants. This ecological diversity is reflected by the diversity and complexity of their genomes. Five canonical structural protein genes are conserved in all rhabdoviruses, but may be overprinted, overlapped or interspersed with several novel and diverse accessory genes. This review gives an overview of the characteristics and diversity of rhabdoviruses, their taxonomic classification, replication mechanism, properties of classical rhabdoviruses such as rabies virus and rhabdoviruses with complex genomes, rhabdoviruses infecting aquatic species, and plant rhabdoviruses with both mono- and bipartite genomes.
authors: Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St. Lucia, Queensland 4072, Australia. Electronic address: r.dietzgen@uq.edu.au.
authors: Ralf G
authors: RG
authors: Dietzgen
authors: Institute of Plant Science and Resources, Okayama University, Kurashiki, 710-0046, Japan.
authors: Hideki
authors: H
authors: Kondo
authors: Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, USA.
authors: Michael M
authors: MM
authors: Goodin
authors: U.S. Geological Survey, Western Fisheries Research Centre, Seattle, WA, USA.
authors: Gael
authors: G
authors: Kurath
authors: Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX, 77555, USA.
authors: Nikos
authors: N
authors: Vasilakis
mesh_terms: D000818:Animals; D058893:DNA Barcoding, Taxonomic; D019143:Evolution, Molecular; D014644:Genetic Variation; D016679:Genome, Viral; D054884:Host-Pathogen Interactions; D010802:Phylogeny; D010942:Plant Viruses / Q000145:classification / Q000502:physiology; D014176:Protein Biosynthesis; D012328:RNA Viruses / Q000145:classification / Q000502:physiology; D012367:RNA, Viral; D012209:Rhabdoviridae / Q000145:classification* / Q000502:physiology*; D014158:Transcription, Genetic; D014714:Vertebrates; D014779:Virus Replication
chemical_list: D012367:RNA, Viral
keywords: Diversity; Genome organization; Negative-sense RNA virus; Replication; Rhabdovirus; Taxonomy