title: Microwave-gated dynamic nuclear polarization.
abstract: Dissolution dynamic nuclear polarization (D-DNP) has become a method of choice to enhance signals in nuclear magnetic resonance (NMR). Recently, we have proposed to combine cross-polarization (CP) with D-DNP to provide high polarization P(13C) in short build-up times. In this paper, we show that switching microwave irradiation off for a few hundreds of milliseconds prior to CP can significantly boost the efficiency. By implementing microwave gating,13C polarizations on sodium [1-13C]acetate as high as 64% could be achieved with a polarization build-up time constant as short as 160 s. A polarization of P(13C) = 78% could even be reached for [13C]urea.
authors: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, 1015 Lausanne, Switzerland.
authors: Aurélien
authors: A
authors: Bornet
authors: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, 1015 Lausanne, Switzerland.
authors: Arthur
authors: A
authors: Pinon
authors: Département de Chimie, Ecole Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolécules (LBM), 24 rue Lhomond, 75005 Paris, France and Sorbonne Universités, UPMC Univ Paris 06, Ecole Normale Supérieure, CNRS, Laboratoire des Biomolécules (LBM), Paris, France.
authors: Aditya
authors: A
authors: Jhajharia
authors: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, 1015 Lausanne, Switzerland and Département de Chimie, Ecole Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolécules (LBM), 24 rue Lhomond, 75005 Paris, France and Sorbonne Universités, UPMC Univ Paris 06, Ecole Normale Supérieure, CNRS, Laboratoire des Biomolécules (LBM), Paris, France.
authors: Mathieu
authors: M
authors: Baudin
authors: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, 1015 Lausanne, Switzerland and Département de Chimie, Ecole Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolécules (LBM), 24 rue Lhomond, 75005 Paris, France and Sorbonne Universités, UPMC Univ Paris 06, Ecole Normale Supérieure, CNRS, Laboratoire des Biomolécules (LBM), Paris, France.
authors: Xiao
authors: X
authors: Ji
authors: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, 1015 Lausanne, Switzerland.
authors: Lyndon
authors: L
authors: Emsley
authors: Département de Chimie, Ecole Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolécules (LBM), 24 rue Lhomond, 75005 Paris, France and Sorbonne Universités, UPMC Univ Paris 06, Ecole Normale Supérieure, CNRS, Laboratoire des Biomolécules (LBM), Paris, France.
authors: Geoffrey
authors: G
authors: Bodenhausen
authors: Department of Electrical Engineering, Technical University of Denmark, Lyngby 2800, Denmark and GE Healthcare, Brøndby 2605, Denmark.
authors: Jan Henrik
authors: JH
authors: Ardenkjaer-Larsen
authors: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, 1015 Lausanne, Switzerland and Bruker BioSpin AG, Industriestrasse 26, 8117 Fällanden, Switzerland and Université de Lyon, Université Claude Bernard Lyon 1, CNRS, ENS de Lyon, Institut des Sciences Analytiques, UMR 5280, 5 rue de la Doua, 69100 Villeurbanne, France. sami.jannin@univ-lyon1.fr.
authors: Sami
authors: S
authors: Jannin