title: FlyBase at 25: looking to the future.
abstract: Since 1992, FlyBase (flybase.org) has been an essential online resource for the Drosophila research community. Concentrating on the most extensively studied species, Drosophila melanogaster, FlyBase includes information on genes (molecular and genetic), transgenic constructs, phenotypes, genetic and physical interactions, and reagents such as stocks and cDNAs. Access to data is provided through a number of tools, reports, and bulk-data downloads. Looking to the future, FlyBase is expanding its focus to serve a broader scientific community. In this update, we describe new features, datasets, reagent collections, and data presentations that address this goal, including enhanced orthology data, Human Disease Model Reports, protein domain search and visualization, concise gene summaries, a portal for external resources, video tutorials and the FlyBase Community Advisory Group.
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA sian@morgan.harvard.edu.
authors: L Sian
authors: 0000-0002-6700-3797
authors: LS
authors: Gramates
authors: Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
authors: Steven J
authors: SJ
authors: Marygold
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: Gilberto Dos
authors: GD
authors: Santos
authors: Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
authors: Jose-Maria
authors: JM
authors: Urbano
authors: Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
authors: Giulia
authors: G
authors: Antonazzo
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: Beverley B
authors: BB
authors: Matthews
authors: Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
authors: Alix J
authors: AJ
authors: Rey
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: Christopher J
authors: CJ
authors: Tabone
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: Madeline A
authors: MA
authors: Crosby
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: David B
authors: DB
authors: Emmert
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: Kathleen
authors: K
authors: Falls
authors: Department of Biology, Indiana University, Bloomington, IN 47405, USA.
authors: Joshua L
authors: JL
authors: Goodman
authors: Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.
authors: Yanhui
authors: Y
authors: Hu
authors: Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
authors: Laura
authors: L
authors: Ponting
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: Andrew J
authors: AJ
authors: Schroeder
authors: Department of Biology, Indiana University, Bloomington, IN 47405, USA.
authors: Victor B
authors: VB
authors: Strelets
authors: Department of Biology, Indiana University, Bloomington, IN 47405, USA.
authors: Jim
authors: J
authors: Thurmond
authors: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors: Pinglei
authors: P
authors: Zhou
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D004195:Disease Models, Animal; D004330:Drosophila / Q000235:genetics*; D056726:Genetic Association Studies; D023281:Genomics / Q000379:methods*; D006801:Humans; D064878:Web Browser