title: Predicting outcome after percutaneous balloon mitral commissurotomy : Role of neutrophil-lymphocyte ratio.
abstract: BACKGROUND
  The value of the neutrophil-lymphocyte ratio (NLR) along with the severity of mitral stenosis (MS) in predicting the outcome of percutaneous balloon mitral commissurotomy (PBMC) has not been studied.
  
  
  METHODS
  Patients with severe MS undergoing PBMC between 2013 and 2014 in a university hospital were prospectively enrolled. Complete blood cell count was obtained upon admission and NLRs were calculated. The correlations between NLR with immediate PBMC success and restenosis in 1 year were evaluated.
  
  
  RESULTS
  In all, 102 patients (80 women) with a mean age of 44.5 ± 13.1 years were enrolled in the study. NLR on admission was 2.6 ± 0.8 and mitral valve area (MVA) was 0.89 ± 0.18 cm2. Patients with a lower MVA at baseline had a higher NLR (p = 0.016). The rate of immediate success was 63 % for PBMC. There was no difference in NLR between patients with regard to early and late failures, as well as those who developed restenosis of the valve. Smaller valve area and the rate of valvular dilatation during PBMC were the only independent factors that predicted early and late failure, respectively.
  
  
  CONCLUSIONS
  NLR at the time of treatment was not useful in predicting procedural outcome or restenosis during follow-up of patients undergoing PBMC.
authors: Cardiovascular Research Center, Tabriz University of Medical Science, Tabriz, Iran.
authors: A
authors: A
authors: Separham
authors: Cardiovascular Research Center, Tabriz University of Medical Science, Tabriz, Iran.|Dept. of Anesthesiology, University at Buffalo, 77 Goodell Street, Suite #510, 14203, Buffalo, NY, USA.
authors: L
authors: L
authors: Pourafkari
authors: Cardiovascular Research Center, Tabriz University of Medical Science, Tabriz, Iran.
authors: H
authors: H
authors: Bodagh
authors: Cardiovascular Research Center, Tabriz University of Medical Science, Tabriz, Iran.
authors: S
authors: S
authors: Ghaffari
authors: Cardiovascular Research Center, Tabriz University of Medical Science, Tabriz, Iran.
authors: N
authors: N
authors: Aslanabadi
authors: Dept. of Anesthesiology, University at Buffalo, 77 Goodell Street, Suite #510, 14203, Buffalo, NY, USA. nnader@buffalo.edu.
authors: N D
authors: ND
authors: Nader
mesh_terms: D000328:Adult; D063126:Balloon Valvuloplasty / Q000379:methods*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000276:immunology / Q000628:therapy*; D009504:Neutrophils / Q000276:immunology*; D011237:Predictive Value of Tests; D012008:Recurrence; D012307:Risk Factors; D016896:Treatment Outcome
keywords: Balloon valvuloplasty; Mitral valve stenosis; Outcome; Percutaneous coronary intervention; Rheumatic heart disease