title: Percutaneous Acetabuloplasty for Metastatic Lesions to the Pelvis.
abstract: Metastatic lesions of the acetabulum can be painful and debilitating. First-line treatment is multimodal and consists of disease-specific chemotherapy, osteoclastic inhibitors, analgesics, and radiation therapy. When these therapies fail, surgical intervention usually is indicated and varies from regional defect stabilization to large periacetabular reconstructions that are demanding procedures with high rates of complications. Percutaneous cement augmentation (acetabuloplasty) of lesions in selected patients has been explored as a less invasive method of lesional control. This retrospective review included 11 patients with painful periacetabular lesions who underwent percutaneous acetabuloplasty using fluoroscopic guidance from 2007 to 2012, in addition to standard treatment with either radiation or chemotherapy, or a combination of both radiation and chemotherapy. Primary tumors included 4 multiple myeloma, 4 renal cell, and 3 breast malignancies. Mean procedure length was 58.4 minutes, and mean hospital stay was 1.4 days (range, 1-2 days). Mean blood loss was 33.4 mL, and there were no complications due to infection or cementation. Mean follow-up was 26.4 months (range, 3-36 months), with 2 patients dying from complications of underlying disease. All of the patients experienced pain relief following the procedure, with mean visual analog scale scores improving from 7.7 to 2.1 (P=.002). Postoperative Musculoskeletal Tumor Society and Oxford hip scores were obtained for 7 of 11 patients and demonstrated improvement. One patient underwent conversion to an acetabular reconstruction due to disease progression. This report demonstrates the effective use of a minimally invasive procedure to provide acute stability, pain relief, and good functional outcomes in patients with periacetabular metastatic lesions without pathologic fracture. [Orthopedics. 2017; 40(1):e170-e175.].
authors: Ryan A
authors: RA
authors: Durfee
authors: Scott A
authors: SA
authors: Sabo
authors: G Douglas
authors: GD
authors: Letson
authors: Odion
authors: O
authors: Binitie
authors: David
authors: D
authors: Cheong
mesh_terms: D065526:Acetabuloplasty / Q000379:methods*; D000077:Acetabulum / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D001843:Bone Cements / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000556:secondary / Q000601:surgery*; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000556:secondary / Q000601:surgery; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology / Q000601:surgery; D010388:Pelvis / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements