title: Achievement of Cure with Gefitinib in Advanced Lung Adenocarcinoma Harboring an ActivatingEGFRMutation: A Case Report.
abstract: Tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) may achieve long-term survival in selected cases with advanced non-small cell lung cancer harboring activating mutations in theEGFRgene, but a cured case has not been reported yet. Here, we present the first case ofEGFR-mutated lung adenocarcinoma cured with an EGFR-TKI, as the 75-year-old Japanese man has achieved complete response with gefitinib treatment and has survived without tumor 10 years after termination of gefitinib treatment.
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Taiji
authors: T
authors: Kuwata
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Kazue
authors: K
authors: Yoneda
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Kenichi
authors: K
authors: Kobayashi
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Rintarou
authors: R
authors: Oyama
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Hiroki
authors: H
authors: Matumiya
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Shuichi
authors: S
authors: Shinohara
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Masaru
authors: M
authors: Takenaka
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Soichi
authors: S
authors: Oka
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Yasuhiro
authors: Y
authors: Chikaishi
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Naoko
authors: N
authors: Imanishi
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Koji
authors: K
authors: Kuroda
authors: Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors: Fumihiro
authors: F
authors: Tanaka
keywords: EGFR TKI; EGFR mutation; Lung cancer