title: Repeated sessions of transcranial direct current stimulation evaluation on fatigue and daytime sleepiness in Parkinson's disease.
abstract: Parkinson is a common and disabling disease that affects patient's and career's quality of life. Unfortunately, medications, such as dopaminergic and sedative-hypnotic drugs, as an effective treatment have unwilling side effects. Recently, Transcranial Direct Current Stimulation (tDCS) in conjunction with medication becomes popular as a complementary safe treatment and several studies have proved its effectiveness on controlling motor and specially non-motor aspects of Parkinson's disease. In this randomized double-blind parallel study, 23 patients with Parkinson's disease divided into two groups of real tDCS plus occupational therapy and sham tDCS plus occupational therapy and the effects of therapeutic sessions (eight sessions tDCS with 0.06 mA/cm2current, 20 min on dorsolateral prefrontal cortex) were evaluated on fatigue and daytime sleepiness just after therapeutic course and in 3-month follow-up. tDCS had a significant effect on fatigue and no effect on daytime sleepiness reduction in patients with Parkinson's disease. tDCS is an effective and safe complementary treatment on fatigue reduction in Parkinson's disease.
authors: Neuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: Bijan
authors: B
authors: Forogh
authors: Neuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: Maryam
authors: M
authors: Rafiei
authors: Neuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: Amin
authors: A
authors: Arbabi
authors: Department of Neurology, Firoozgar hospitalIran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: Mohammad Reza
authors: MR
authors: Motamed
authors: Neuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: Seyed Pezhman
authors: SP
authors: Madani
authors: Burn Research Center, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran. dr.sajadi_pmr@yahoo.com.
authors: Simin
authors: S
authors: Sajadi
mesh_terms: D000328:Adult; D000359:Aftercare; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D006970:Disorders of Excessive Somnolence / Q000209:etiology / Q000628:therapy*; D004311:Double-Blind Method; D005221:Fatigue / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009788:Occupational Therapy; D017063:Outcome Assessment, Health Care; D010300:Parkinson Disease / Q000150:complications / Q000628:therapy*; D065908:Transcranial Direct Current Stimulation / Q000379:methods*
keywords: Daytime sleepiness; Fatigue; Parkinson’s disease; Transcranial direct current stimulation