title: Chemical O-Glycosylations: An Overview.
abstract: The development of glycobiology relies on the sources of particular oligosaccharides in their purest forms. As the isolation of the oligosaccharide structures from natural sources is not a reliable option for providing samples with homogeneity, chemical means become pertinent. The growing demand for diverse oligosaccharide structures has prompted the advancement of chemical strategies to stitch sugar molecules with precise stereo- and regioselectivity through the formation of glycosidic bonds. This Review will focus on the key developments towards chemical O-glycosylations in the current century. Synthesis of novel glycosyl donors and acceptors and their unique activation for successful glycosylation are discussed. This Review concludes with a summary of recent developments and comments on future prospects.
authors: Department of Chemical Sciences Indian Institute of Science Education and Research (IISER) Kolkata Mohanpur Nadia 741246 India.
authors: Rituparna
authors: R
authors: Das
authors: Department of Chemical Sciences Indian Institute of Science Education and Research (IISER) Kolkata Mohanpur Nadia 741246 India.
authors: Balaram
authors: B
authors: Mukhopadhyay
keywords: catalysis; glycosylation reactions; promoters; protecting groups; stereoselectivity