title: Molecular characterization of ESBL-producing Escherichia coli isolates from hospital- and community-acquired infections in NW Mexico.
abstract: We investigated the molecular characteristics of ESBL-producing E. coli (ESBL-PEc) isolates from two hospitals and community settings in Ciudad Obregon, Sonora, Mexico. Between 2011 and 2014, thirty-seven ESBL-PEc isolates were collected. The major encoded ESBL was the blaCTX-M-15gene (97%); followed by 13.5% of the blaSHV-12gene, and 5.5% encoded the blaTLA-1gene. The PMQR gene aac(6´)-Ib-cr was detected in 97% of the isolates and the qnrB gene, in one isolate. The ESBL-PEc isolates corresponded to phylogenetic group B2, ST131. Our results highlight the dissemination of ESBL-PEc isolates in northwest Mexico (Ciudad Obregon, Sonora).
authors: Actual address: Departamento de Ciencias Agronómicas y Veterinarias, Instituto Tecnológico de Sonora, Cajeme, Mexico; Instituto Nacional de Salud Pública, Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Departamento de Diagnóstico Epidemiológico, Cuernavaca, Morelos, Mexico.
authors: Ana Laura
authors: AL
authors: Miranda-Romero
authors: Instituto Nacional de Salud Pública, Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Departamento de Diagnóstico Epidemiológico, Cuernavaca, Morelos, Mexico. Electronic address: jsilva@insp.mx.
authors: Jesus
authors: J
authors: Silva-Sanchez
authors: Instituto Nacional de Salud Pública, Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Departamento de Diagnóstico Epidemiológico, Cuernavaca, Morelos, Mexico.
authors: Ulises
authors: U
authors: Garza-Ramos
authors: Instituto Nacional de Salud Pública, Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Departamento de Diagnóstico Epidemiológico, Cuernavaca, Morelos, Mexico.
authors: Humberto
authors: H
authors: Barrios
authors: Instituto Nacional de Salud Pública, Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Departamento de Diagnóstico Epidemiológico, Cuernavaca, Morelos, Mexico.
authors: Alejandro
authors: A
authors: Sánchez-Pérez
authors: Instituto Nacional de Salud Pública, Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Departamento de Diagnóstico Epidemiológico, Cuernavaca, Morelos, Mexico.
authors: Fernando
authors: F
authors: Reyna-Flores
mesh_terms: D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004926:Escherichia coli / Q000145:classification / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D005798:Genes, Bacterial; D005838:Genotype; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D010802:Phylogeny; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases
keywords: Hospital and community isolates; PMQR; Quinolone resistance; β-Lactamases