title: Clinical Outcomes of Endoscopic Removal in Patients with Colorectal Polypoid Leiomyomas.
abstract: OBJECTIVE
  Although polypoid leiomyomas in the colon and rectum are rare, they are increasingly detected during colonoscopy. The aim of this study was to evaluate the efficacy and clinical outcomes of endoscopic removal for colorectal polypoid leiomyoma.
  
  
  METHODS
  Data were retrospectively collected from 22 patients with polypoid leiomyoma arising from the muscularis mucosae in the colon and rectum who underwent endoscopic removal at single referral gastrointestinal endoscopy unit. Colonoscopic findings, endoscopic removal, success rates, complication rates (bleeding or perforation), pathologic characteristics, and recurrence rates were investigated.
  
  
  RESULTS
  Most polypoid leiomyomas were small asymptomatic lesions less than 1 cm. The tumors were located predominantly in the left colon. Ten leiomyomas were removed using cold biopsy forceps, and 12 were resected by conventional polypectomy or endoscopic mucosal resection. All tumors arose from or involved the muscularis mucosa. There were no complications, such as bleeding or perforation. No local remnant lesions were found in 19 patients who underwent at least one follow-up colonoscopy.
  
  
  CONCLUSIONS
  This case series represent cases of small colorectal polypoid leiomyoma that were safely removed endoscopically. An awareness of their endoscopic and clinic-pathological characteristics may provide safe treatment strategy for colonic leiomyomatous tumors of similar size in capable hands.
authors: Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University, Uijeongbu, Korea.
authors: Hyun Ho
authors: HH
authors: Choi
authors: Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University, Seoul, Korea.
authors: Young Seok
authors: YS
authors: Cho
authors: Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University, Uijeongbu, Korea.
authors: Soo Kyoung
authors: SK
authors: Choi
authors: Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University, Uijeongbu, Korea.
authors: Hyung Keun
authors: HK
authors: Kim
authors: Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University, Uijeongbu, Korea.
authors: Sung Soo
authors: SS
authors: Kim
authors: Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University, Uijeongbu, Korea.
authors: Hiun Suk
authors: HS
authors: Chae
authors: Department of Hospital Pathology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University, Uijeongbu, Korea.
authors: Ok Ran
authors: OR
authors: Shin
mesh_terms: D000199:Actins / Q000378:metabolism; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003111:Colonic Polyps / Q000473:pathology*; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D003893:Desmin / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: C541116:ACTA2 protein, human; D000199:Actins; D003893:Desmin
keywords: Colonic polyps; Colonoscopy; Colorectal neoplasms; Leiomyoma