title: Acute Rheumatic Fever: Global Persistence of a Preventable Disease.
abstract: The persistence of acute rheumatic fever continues to be seen globally. Once thought to be eradicated in various parts of the world, the disease came back with a vengeance secondary to a lack of diligence on the part of providers. Today, the global burden of group A streptococcal infection, the culprit of the numerous sequelae manifested in acute rheumatic fever, is considerable. Although a completely preventable disease, rheumatic fever continues to exist. It is a devastating disease that involves long-term, multisystem treatment and monitoring for patients who were unsuccessful at eradicating the precipitating group A streptococcal infection. Prevention is the key to resolving the dilemma of the disease's global burden, yet the method to yield its prevention still remains unknown. Thus, meticulous attention to implementing proper treatment is the mainstay and remains a top priority.
authors: Francine
authors: F
authors: Bono-Neri
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D004334:Drug Administration Schedule; D005260:Female; D014943:Global Health; D006801:Humans; D008297:Male; D010612:Pharyngitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D012213:Rheumatic Fever / Q000188:drug therapy / Q000453:epidemiology* / Q000517:prevention & control; D055502:Secondary Prevention / Q000379:methods*; D013290:Streptococcal Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Acute rheumatic fever (ARF); Jones criteria; carditis; group A Streptococcus (GAS); pharyngitis