title: Point-to-Point Ultra-Remote Asymmetric Control with Flexible Linker.
abstract: An ultra-remote intramolecular (point-to-point) asymmetric control through 38 bonds (1,39-asymmetric induction) has been achieved by using the principle of direct supramolecular orientation of catalytic and reactive moieties in asymmetric autocatalysis. We found the highly stereoselective diisopropylzinc addition reaction using designed molecules possessing pyrimidine sites at each terminal of a conformationally flexible simple methylene chain.
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.|Research Center for Chirality, Research Institute for Science and Technology (RIST), Tokyo University of Science, Japan.|Department of Materials Science and Engineering, University of Fukui, Bunkyo, Fukui, 910-8507, Japan.
authors: Tsuneomi
authors: T
authors: Kawasaki
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.
authors: Yasuyuki
authors: Y
authors: Ishikawa
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.
authors: Yoshihiro
authors: Y
authors: Minato
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.
authors: Takashi
authors: T
authors: Otsuka
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.
authors: Shigeru
authors: S
authors: Yonekubo
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.|Graduate School of Science and Engineering, Ibaraki University, Bunkyo, Ibaraki, 310-8512, Japan.
authors: Itaru
authors: I
authors: Sato
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.|Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University, Shinjuku, Tokyo, 169-8555, Japan.
authors: Takanori
authors: T
authors: Shibata
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.|Research Center for Chirality, Research Institute for Science and Technology (RIST), Tokyo University of Science, Japan.
authors: Arimasa
authors: A
authors: Matsumoto
authors: Department of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.|Research Center for Chirality, Research Institute for Science and Technology (RIST), Tokyo University of Science, Japan.
authors: Kenso
authors: K
authors: Soai
keywords: 5-pyrimidyl alkanol; asymmetric amplification; intramolecular stereocontrol; remote asymmetric induction; stereoselective reaction