title: [Pyoderma gangrenosum and Sweet's syndrome : Cutaneous manifestations of autoinflammatory disorders].
abstract: Pyoderma gangrenosum and Sweet's syndrome are rare diseases that belong to the group of neutrophilic dermatoses and share several common characteristics. Although the two disorders differ clinically from each other, both diseases show pronounced dermal infiltration of neutrophils without evidence of primary vasculitis and respond well to immunosuppressive drugs. In addition, both diseases are often associated with other systemic and hematological disorders. Recent findings show that the neutrophil dermatoses can be considered as cutaneous manifestations of autoinflammation, demonstrating an interesting new aspect in the development of the diseases and additional therapeutic avenues.
authors: Klinik für Dermatologie, Universitätsspital Zürich, Gloriastr. 31, 8091, Zürich, Schweiz. barbara.meier2@usz.ch.
authors: B
authors: B
authors: Meier
authors: Klinik für Dermatologie, Universitätsspital Zürich, Gloriastr. 31, 8091, Zürich, Schweiz.
authors: J-T
authors: JT
authors: Maul
authors: Klinik für Dermatologie, Universitätsspital Zürich, Gloriastr. 31, 8091, Zürich, Schweiz.
authors: L E
authors: LE
authors: French
mesh_terms: D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D056660:Hereditary Autoinflammatory Diseases / Q000175:diagnosis* / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000175:diagnosis* / Q000188:drug therapy* / Q000276:immunology; D016463:Sweet Syndrome / Q000175:diagnosis* / Q000188:drug therapy* / Q000276:immunology; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents
keywords: Immune system; Immunosuppressants; Interleukin-1β; Neutrophilic dermatosis; Steroids