title: Persistent Corneal Edema Associated With Subconjunctival 5-fluorouracil in an Infant With Primary Congenital Glaucoma.
abstract: A 3-month-old boy with primary congenital glaucoma developed a transient corneal endothelial opacity after needle bleb revision with adjunctive 5-fluorouracil. This case presents a rare toxicity that, although transient, is concerning due to the potential of amblyopia. The authors review prior cases of corneal opacity associated with 5-fluorouracil. [J Pediatr Ophthalmol Strabismus. 2016;53:e54-e57.].
authors: Gregory L
authors: GL
authors: Fu
authors: Janet L
authors: JL
authors: Alexander
authors: Osamah J
authors: OJ
authors: Saeedi
mesh_terms: D000963:Antimetabolites / Q000009:adverse effects*; D003228:Conjunctiva; D015715:Corneal Edema / Q000139:chemically induced*; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D006871:Hydrophthalmos / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D007223:Infant; D056965:Injections, Intraocular; D008297:Male; D009339:Needles
chemical_list: D000963:Antimetabolites; D005472:Fluorouracil