title: Epidemiology of American Tegumentary Leishmaniasis andTrypanosoma cruziInfection in the Northwestern Argentina.
abstract: Background. Endemic areas of tegumentary leishmaniasis (TL) in Salta, Argentina, present some overlap zones with the geographical distribution of Chagas disease, with mixed infection cases being often detected.Objectives. The purpose of this study was to determine the magnitude ofLeishmaniasp. infection and potential associated risk factors, the serologic prevalence ofT. cruzi,and the presence ofT. cruzi-Leishmaniasp. mixed infection in a region of the northwest of Argentina.Methods. Cross-sectional studies were conducted to detect TL prevalence andT. cruziseroprevalence. A case-control study was conducted to examine leishmaniasis risk factors.Results. Prevalence of TL was 0.17%, seroprevalence ofT. cruziinfection was 9.73%, and mixed infection proportion-within the leishmaniasic patients group-was 16.67%. The risk factors associated with TL transmission were sex, age, exposure to bites at work, staying outdoors more than 10 hours/day, bathing in the river, and living with people who had lesions or were infected during the study.Discussion. The endemic pattern of TL seems to involve exposure of patients to vectors in wild as well as peridomestic environment. Cases ofT. cruziinfection are apparently due to migration. Therefore, a careful epidemiological surveillance is necessary due to the contraindication of antimonial administration to chagasic patients.
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina.
authors: Carlos L
authors: CL
authors: Hoyos
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina.
authors: Silvana P
authors: SP
authors: Cajal
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina.
authors: Marisa
authors: M
authors: Juarez
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina; Instituto de Patología Experimental (IPE-CONICET), Facultad de Ciencias de la Salud, Universidad Nacional de Salta, 4400 Salta, Argentina.
authors: Jorge D
authors: JD
authors: Marco
authors: Instituto de Patología Experimental (IPE-CONICET), Facultad de Ciencias de la Salud, Universidad Nacional de Salta, 4400 Salta, Argentina.
authors: Anahí M
authors: AM
authors: Alberti D'Amato
authors: Instituto de Biología de la Altura (InBiAl), Universidad Nacional de Jujuy, Jujuy, Argentina.
authors: Melina
authors: M
authors: Cayo
authors: Instituto de Biología de la Altura (InBiAl), Universidad Nacional de Jujuy, Jujuy, Argentina.
authors: Irma
authors: I
authors: Torrejón
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina; Cátedra de Química Biológica, Facultad de Ciencias Naturales, Universidad Nacional de Salta, 4400 Salta, Argentina.
authors: Rubén O
authors: RO
authors: Cimino
authors: Instituto de Patología Experimental (IPE-CONICET), Facultad de Ciencias de la Salud, Universidad Nacional de Salta, 4400 Salta, Argentina.
authors: Patricio
authors: P
authors: Diosque
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina; Instituto de Patología Experimental (IPE-CONICET), Facultad de Ciencias de la Salud, Universidad Nacional de Salta, 4400 Salta, Argentina.
authors: Alejandro J
authors: 0000-0001-9054-1211
authors: AJ
authors: Krolewiecki
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina; Cátedra de Química Biológica, Facultad de Ciencias Naturales, Universidad Nacional de Salta, 4400 Salta, Argentina.
authors: Julio R
authors: JR
authors: Nasser
authors: Instituto de Investigaciones en Enfermedades Tropicales, Sede Regional Orán, Universidad Nacional de Salta, 4530 Salta, Argentina; Instituto de Investigaciones en Energía no Convencional (INENCO-CONICET), Universidad Nacional de Salta, 4400 Salta, Argentina.
authors: José F
authors: 0000-0003-3994-1265
authors: JF
authors: Gil
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001118:Argentina / Q000453:epidemiology; D016022:Case-Control Studies; D014355:Chagas Disease / Q000453:epidemiology; D002648:Child; D060085:Coinfection / Q000453:epidemiology / Q000469:parasitology*; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005843:Geography; D006801:Humans; D007896:Leishmaniasis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D065947:Rainforest; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D014329:Tropical Climate; D014349:Trypanosoma cruzi; D014352:Trypanosomiasis / Q000453:epidemiology*; D055815:Young Adult