title: HLA-A, -B and -DRB1 genotyping and haplotype frequencies of 3892 cord blood units in the Hong Kong Chinese Cord Blood Registry.
abstract: HLA-A, -B and -DRB1 gene and haplotype frequencies have been calculated from 3892 southern Chinese unrelated cord blood units in a Hong Kong Cord Blood Registry. This is the first large-scale paper to report the distribution of A-B-DRB1 alleles in Hong Kong Chinese Cord Blood Units. This information is important for estimating the optimal and economically cost-effective donor size and likelihood of obtaining appropriately matched cord blood units for Chinese patients awaiting haematopoietic stem cell transplantation. The data are available in the Allele Frequencies Net Database under the population name ''Hong Kong Chinese Cord Blood Registry'' and the identifier (AFND003358).
authors: Division of Transplantation and Immunogenetics, Queen Mary Hospital, Hong Kong. Electronic address: kwoksy@ha.org.hk.
authors: Janette
authors: J
authors: Kwok
authors: Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong.
authors: Mengbiao
authors: M
authors: Guo
authors: Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong.
authors: Wanling
authors: W
authors: Yang
authors: Hong Kong Red Cross Blood Transfusion Service, Hong Kong.
authors: C K
authors: CK
authors: Lee
authors: Hong Kong Red Cross Blood Transfusion Service, Hong Kong.
authors: N K
authors: NK
authors: Chan
authors: Division of Transplantation and Immunogenetics, Queen Mary Hospital, Hong Kong.
authors: Jenny
authors: J
authors: Ho
authors: Division of Transplantation and Immunogenetics, Queen Mary Hospital, Hong Kong.
authors: W H
authors: WH
authors: Tang
authors: Division of Transplantation and Immunogenetics, Queen Mary Hospital, Hong Kong.
authors: Y S
authors: YS
authors: Chan
authors: Transplant Immunology, Royal Liverpool Hospital, Liverpool, UK.
authors: Derek
authors: D
authors: Middleton
authors: Department of Pathology, The University of Hong Kong, Hong Kong.
authors: L W
authors: LW
authors: Lu
authors: Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong.
authors: Godfrey C F
authors: GC
authors: Chan
mesh_terms: D044466:Asian People; D001771:Blood Banks; D005312:Fetal Blood / Q000637:transplantation; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D015234:HLA-A Antigens / Q000235:genetics*; D015235:HLA-B Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains / Q000235:genetics*; D006239:Haplotypes; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006723:Hong Kong; D006801:Humans; D012042:Registries
chemical_list: D015234:HLA-A Antigens; D015235:HLA-B Antigens; D059811:HLA-DRB1 Chains
keywords: Chinese; Cord blood; Gene frequency; HLA; Haplotype frequency; Hong Kong; Registry