title: Summary of the Update Session on Clinical Neurotoxicity Studies.
abstract: During the Fifth Pediatric Anesthesia Neurodevelopmental Assessment Symposium, experts and stakeholders met to present and discuss recent advances made in the study of neurodevelopmental outcomes after exposure to anesthetic drugs in infants and children. This article summarizes the update of 5 ongoing clinical studies: General Anesthesia compared to Spinal Anesthesia, Toxicity of Remifentanil and Dexmedetomidine, Mayo Anesthesia Safety in Kids, the University of California San Francisco human cohort study, and Columbia University Medical Center Neonatal Magnetic Resonance Imaging study. The purpose of this summary is to discuss the contributions and limitations of these studies, how they fit into the published literature, and what questions remain to be answered.
authors: Departments of *Anesthesiology#Psychiatry, Columbia University College of Physicians and Surgeons, New York, NYDepartments of †Anesthesiology‡Pediatrics, Mayo Clinic College of Medicine, Rochester, MN§Department of Anesthesiology, Harvard Medical School, Boston, MA∥Department of Anesthesiology and Department of Pediatrics, Baylor College of Medicine, Houston, TX¶Department of Anesthesiology and Perioperative Care, University of California San Francisco School of Medicine, San Francisco, CA.
authors: Teeda
authors: T
authors: Pinyavat
authors: David O
authors: DO
authors: Warner
authors: Randall P
authors: RP
authors: Flick
authors: Mary Ellen
authors: ME
authors: McCann
authors: Dean B
authors: DB
authors: Andropoulos
authors: Danquig
authors: D
authors: Hu
authors: Jeffrey W
authors: JW
authors: Sall
authors: Marisa N
authors: MN
authors: Spann
authors: Caleb
authors: C
authors: Ing
mesh_terms: D000777:Anesthetics / Q000009:adverse effects*; D001921:Brain / Q000187:drug effects*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D020258:Neurotoxicity Syndromes / Q000209:etiology* / Q000503:physiopathology
chemical_list: D000777:Anesthetics