title: MIToS.jl: mutual information tools for protein sequence analysis in the Julia language.
abstract: MIToS is an environment for mutual information analysis and a framework for protein multiple sequence alignments (MSAs) and protein structures (PDB) management in Julia language. It integrates sequence and structural information through SIFTS, making Pfam MSAs analysis straightforward. MIToS streamlines the implementation of any measure calculated from residue contingency tables and its optimization and testing in terms of protein contact prediction. As an example, we implemented and tested a BLOSUM62-based pseudo-count strategy in mutual information analysis.
  
  
  
  The software is totally implemented in Julia and supported for Linux, OS X and Windows. It's freely available on GitHub under MIT license: http://mitos.leloir.org.ar .
  
  
  
  diegozea@gmail.com or cmb@leloir.org.ar.
  
  
  
  Supplementary data are available at Bioinformatics online.
authors: Structural Bioinformatics Unit, Fundación Instituto Leloir, C1405BWE, Ciudad Autónoma de Buenos Aires, Argentina.
authors: Diego J
authors: DJ
authors: Zea
authors: Structural Bioinformatics Unit, Fundación Instituto Leloir, C1405BWE, Ciudad Autónoma de Buenos Aires, Argentina.
authors: Diego
authors: D
authors: Anfossi
authors: Center for Biological Sequence Analysis, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.|Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, 1650 San Martín, Buenos Aires, Argentina.
authors: Morten
authors: M
authors: Nielsen
authors: Structural Bioinformatics Unit, Fundación Instituto Leloir, C1405BWE, Ciudad Autónoma de Buenos Aires, Argentina.
authors: Cristina
authors: C
authors: Marino-Buslje
mesh_terms: D006801:Humans; D011487:Protein Conformation; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software