title: A rare case of a pineoblastoma with a rhabdomyoblastic component.
abstract: Pineal anlage tumor (PAT) is a rare subtype of pineoblastoma (PB), which shows a poor prognosis. We report a case of a 5-year-old boy with PB with a rhabdomyoblastic component. He presented at a local clinic with vomiting and was transferred to our hospital following discovery of a pineal mass. An endoscopic biopsy was performed and was diagnosed as a PB with a rhabdomyoblastic component. Histopathology of PAT is characterized by both neuroectodermal and ectomesenchymal differentiation, and only a few confirmed cases have been reported. Although the histopathological features of the reported case resembled that of PAT, the ectomesenchymal component in the presented case was only a rhabdomyoblastic one. Therefore, we have diagnosed this case as PB with a rhabdomyoblastic component. As PAT is a rare pineal tumor, clinical, histopathological and genetic evaluation of additional cases is needed to define the characteristics of PAT as one of the pineal gland tumors.
authors: Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors: Taku
authors: T
authors: Homma
authors: Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.|Department of Pathology, Nihon University Hospital, Chiyoda, Tokyo, Japan.
authors: Akihiro
authors: A
authors: Hemmi
authors: Department of Neurological Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors: Takashi
authors: T
authors: Ohta
authors: Division of Oncologic Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors: Yoshiaki
authors: Y
authors: Kusumi
authors: Department of Neurological Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors: Atsuo
authors: A
authors: Yoshino
authors: Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors: Hiroyuki
authors: H
authors: Hao
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010870:Pineal Gland / Q000000981:diagnostic imaging / Q000473:pathology*; D010871:Pinealoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D012206:Rhabdomyolysis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*
keywords: medullomyoblastoma; pineal anlage tumor; pineal gland; pineoblastoma; rhabdomyoblastic component