title: A Review on the Reversal of the Old and New Anticoagulants.
abstract: It is not uncommon for providers in the emergency department to take care of patients who are taking anticoagulant therapy in the outpatient setting. However, the bigger challenge is caring for these patients when they present with bleeding that could be secondary to 1 or more of these medications. In recent years, this class of medications has expanded from warfarin to include direct thrombin inhibitors and Factor Xa inhibitors. As this class of medications has evolved, so has the approach to the reversal of these agents. Thus, it is imperative that providers in the emergency department be familiar not only with the anticoagulants that patients may be taking in the outpatient setting but also with their reversal agents.
authors: University of Kentucky HealthCare, Lexington (Drs Bailey, Blackburn, and Horn); University of Kentucky College of Pharmacy, Lexington (Dr Bailey); Charleston Area Medical Center, Charleston, West Virginia (Drs Crowley and Schultz); University of Charleston School of Pharmacy, Charleston, West Virginia (Drs Crowley and Schultz); West Virginia University School of Pharmacy, Morgantown (Drs Crowley and Schultz); and St. Claire Regional Medical Center, Morehead, Kentucky (Dr Justice).
authors: Abby Mynatt
authors: AM
authors: Bailey
authors: Matthew C
authors: MC
authors: Blackburn
authors: John M
authors: JM
authors: Crowley
authors: Kari S
authors: KS
authors: Horn
authors: Amy E
authors: AE
authors: Schultz
authors: Stephanie Baker
authors: SB
authors: Justice
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D000931:Antidotes / Q000627:therapeutic use*; D004636:Emergency Service, Hospital; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control; D006801:Humans
chemical_list: D000925:Anticoagulants; D000931:Antidotes