title: Comparing pattern scanning laser trabeculoplasty to selective laser trabeculoplasty: A randomized controlled trial.
abstract: OBJECTIVE
  To compare safety, tolerability and intraocular pressure (IOP)-lowering efficacy of pattern scanning laser trabeculoplasty (PSLT) with selective laser trabeculoplasty (SLT) in fellow eyes of untreated patients with glaucoma.
  
  
  METHODS
  Randomized controlled trial.
  
  
  METHODS
  Twenty-nine patients (58 eyes) with primary and secondary open angle glaucoma (OAG) were randomized to undergo PSLT or SLT in each eye.
  
  
  METHODS
  Pattern scanning laser trabeculoplasty was performed using the Pascal laser (Pascal Streamline 577; Topcon Inc., Tokyo, Japan). Patients' comfort level to treatment was assessed using a visual analogue scale (VAS). Follow-up visits were at week 1, month 1, 3 and 6. Success was defined as IOP reduction ≥20%.
  
  
  METHODS
  Safety, tolerability and IOP reduction.
  
  
  RESULTS
  The mean age of patients was 54.1 ± 15.5 years. Baseline IOP was similar between both groups (PSLT, 17.3 ± 4.0 mmHg; SLT, 16.8 ± 3.6 mmHg, p > 0.05). In the PSLT group, the mean IOP at 1, 3 and 6 months was 14.2 ± 3.5, 13.9 ± 2.6 and 14.0 ± 2.7 mmHg, respectively. In the SLT group, the mean IOP at 1, 3 and 6 months was 14.4 ± 4.1, 13.7 ± 3.2 and 13.7 ± 3.1 mmHg, respectively. The IOP reduction in the PSLT group was greater than the SLT group at 1 month (p < 0.01) and 3 months (p < 0.01). VAS score was better in PSLT eyes: 23.9 ± 20.5 (range, 0-82) than in SLT eyes: 50.4 ± 25.3 (range, 0-98) (p < 0.001). No serious adverse events were recorded.
  
  
  CONCLUSIONS
  Both laser modalities had similar safety and efficacy profiles while PSLT was better tolerated by patients.
authors: Department of Ophthalmology, University of Colorado School of Medicine, Denver, CO, USA.|Glaucoma Center, Montchoisi Clinic, Swiss Vision Network, Lausanne, Switzerland.
authors: Kaweh
authors: K
authors: Mansouri
authors: Glaucoma Sector, Department of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland.
authors: Tarek
authors: T
authors: Shaarawy
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D013997:Time Factors; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult
keywords: glaucoma; laser trabeculoplasty; pattern scanning laser trabeculoplasty; selective laser trabeculoplasty