title: Additional value of hybrid SPECT/CT systems in neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas.
abstract: The aim of this review was to evaluate the potential advantages of SPECT/CT hybrid imaging in the management of neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas. From the collected data, the superiority of fused images was observed as providing both functional/molecular and morphological imaging compared to planar imaging. This provided an improvement in diagnostic imaging, with significant advantages as regards: (1) precise locating of the lesions; (2) an improvement in characterization of the findings, resulting higher specificity, improved sensitivity, and overall greater accuracy, (3) additional anatomical information derived from the CT component; (4) CT-based attenuation correction and potential for volumetric dosimetry calculations, and (5) improvement on the impact on patient management (e.g. in better defining treatment plans, in shortening surgical operating times). It can be concluded that SPECT/CT hybrid imaging provides the nuclear medicine physician with a powerful imaging modality in comparison to planar imaging, providing essential information about the location of lesions, and high quality homogeneous images.
authors: Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, MI, USA; Nuclear Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
authors: K K
authors: KK
authors: Wong
authors: Department of Nuclear Medicine, Radiology, NeuroRadiology, Medical Physics, Clinical Laboratory, Molecular Laboratory, Microbiology, Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italy.
authors: S
authors: S
authors: Chondrogiannis
authors: Department of Nuclear Medicine, Hospital Clínic, Barcelona, Spain.
authors: D
authors: D
authors: Fuster
authors: Department of Nuclear Medicine, Hospital Clínic, Barcelona, Spain.
authors: C
authors: C
authors: Ruiz
authors: Department of Nuclear Medicine, Radiology, NeuroRadiology, Medical Physics, Clinical Laboratory, Molecular Laboratory, Microbiology, Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italy.
authors: M C
authors: MC
authors: Marzola
authors: Nuclear Medicine Department, University of Lyon, Lyon, France.
authors: F
authors: F
authors: Giammarile
authors: Department of Nuclear Medicine, University of Southern California, Los Angeles, CA, USA.
authors: P M
authors: PM
authors: Colletti
authors: Department of Nuclear Medicine, Radiology, NeuroRadiology, Medical Physics, Clinical Laboratory, Molecular Laboratory, Microbiology, Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italy. Electronic address: rubello.domenico@azisanrovigo.it.
authors: D
authors: D
authors: Rubello
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging; D006801:Humans; D009363:Neoplasm Proteins / Q000032:analysis; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging*; D015282:Octreotide / Q000031:analogs & derivatives; D010235:Paraganglioma / Q000000981:diagnostic imaging; D010673:Pheochromocytoma / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin / Q000032:analysis; D000072098:Single Photon Emission Computed Tomography Computed Tomography / Q000295:instrumentation / Q000379:methods*; D051598:Whole Body Imaging / Q000379:methods
chemical_list: D009363:Neoplasm Proteins; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; D015282:Octreotide
keywords: Adrenal tumors; Feocromocitoma; Hybrid systems; Imagen híbrida; Neuroendocrine tumors; Paraganglioma; Pheochromocytoma; SPECT/CT; SPECT/TC; Tumores adrenales; Tumores neuroendocrinos