title: Epidemiology and etiology of hand, foot, and mouth disease in Fujian province, 2008-2014.
abstract: Millions of cases of hand, foot, and mouth disease (HFMD) have been reported annually in mainland China since 2008. In this study, we investigated the epidemiology and etiology of an HFMD epidemic in Fujian province, which is located in subtropical southeastern China. Our study found similar epidemiological features of HFMD in southern areas of China, including seasonality and demographic distribution, as well as correlation between severity of illness and serotype. At least 22 serotypes of other enterovirus co-circulating with enterovirus 71 were found to belong to clade C4a, and those circulating with coxsackievirus A16 were associated with clades B1a and B1b.
authors: Division of Viral Disease, Fujian Provincial Center for Disease Prevention and Control, Fuzhou, 350001, Fujian, China.|Public Health School of Fujian Medical University, Fuzhou, 350004, Fujian, China.
authors: Yuwei
authors: Y
authors: Weng
authors: Division of Viral Disease, Fujian Provincial Center for Disease Prevention and Control, Fuzhou, 350001, Fujian, China.
authors: Wei
authors: W
authors: Chen
authors: Division of Viral Disease, Fujian Provincial Center for Disease Prevention and Control, Fuzhou, 350001, Fujian, China.
authors: Meng
authors: M
authors: Huang
authors: Division of Viral Disease, Fujian Provincial Center for Disease Prevention and Control, Fuzhou, 350001, Fujian, China.
authors: Wenxiang
authors: W
authors: He
authors: Division of Viral Disease, Fujian Provincial Center for Disease Prevention and Control, Fuzhou, 350001, Fujian, China.
authors: Kuicheng
authors: K
authors: Zheng
authors: Division of Viral Disease, Fujian Provincial Center for Disease Prevention and Control, Fuzhou, 350001, Fujian, China. yyshfjcdc@163.com.|Public Health School of Fujian Medical University, Fuzhou, 350004, Fujian, China. yyshfjcdc@163.com.
authors: Yansheng
authors: Y
authors: Yan
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004770:Enterovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D004769:Enterovirus Infections / Q000453:epidemiology* / Q000473:pathology / Q000635:transmission / Q000821:virology; D058872:Epidemics; D005260:Female; D006232:Hand, Foot and Mouth Disease / Q000453:epidemiology* / Q000473:pathology / Q000635:transmission / Q000821:virology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010802:Phylogeny; D012621:Seasons; D065288:Serogroup; D012720:Severity of Illness Index
keywords: Enterovirus; Epidemiology; Etiology; Hand, foot, and mouth disease