title: N-HO and N-HCl supported 1D chains of heterobimetallic CuII/NiII-SnIVcocrystals.
abstract: The Schiff base H2L1[N,N'-ethylenebis(3-methoxysalicylaldimine)] or H2L2[N,N'-ethylenebis(3-ethoxysalicylaldimine)] was reacted with MCl2·xH2O and SnCl4·5H2O to afford the supramolecular heterobimetallic systems (H2ED)2+·2[ML]·[SnCl6]2-[M = Cu, L = L1(1), L = L2(2); M = Ni, L = L1(3), L = L2(4); ED = 1,2-ethylenediamine], whose structures were established by single crystal X-ray analyses. Each structure includes different entities, viz. a mononuclear [CuL]/[NiL] neutral complex (coformer), a hexachlorostannate dianion [SnCl6]2-, a 1,2-ethylenediammonium dication (H2ED2+) and, only in 2 and 4, a methanol molecule. Based on the work of Grothe et al. (Cryst. Growth Des., 2016, 16, 3237-3243), compounds 1 and 3 are cocrystal salts, 2 and 4 are cocrystal salt solvates. The ionic pairs (H2ED)2+·[SnCl6]2-in 1-4 are encapsulated by the Cu- or Ni-complexes, and stabilized by N-HO and one N-HCl bond interactions leading to infinite 1D chains. The antimicrobial studies of 1-4 against yeasts (C. albicans and S. cerevisiae) and Gram-positive (S. aureus and E. faecalis) and -negative bacteria (P. aeruginosa and E. coli) indicate that the Ni2Sn systems (3 and 4) are more active than the analogous Cu2Sn ones (1 and 2).
authors: Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisbon, Portugal. h.susanta@gmail.com fatima.guedes@tecnico.ulisboa.pt pombeiro@tecnico.ulisboa.pt.
authors: Susanta
authors: S
authors: Hazra
authors: Ricardo
authors: R
authors: Meyrelles
authors: Adilia Januário
authors: AJ
authors: Charmier
authors: Patrícia
authors: P
authors: Rijo
authors: M Fátima C
authors: MF
authors: Guedes da Silva
authors: Armando J L
authors: AJ
authors: Pombeiro
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002177:Candidiasis / Q000188:drug therapy; D056831:Coordination Complexes / Q000737:chemistry* / Q000494:pharmacology; D003300:Copper / Q000737:chemistry* / Q000494:pharmacology; D003460:Crystallization; D018360:Crystallography, X-Ray; D006801:Humans; D008958:Models, Molecular; D009532:Nickel / Q000737:chemistry* / Q000494:pharmacology; D012545:Schiff Bases / Q000737:chemistry* / Q000494:pharmacology; D014001:Tin / Q000737:chemistry* / Q000494:pharmacology; D015003:Yeasts / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D056831:Coordination Complexes; D012545:Schiff Bases; D014001:Tin; D003300:Copper; D009532:Nickel