title: Sclerosing Orbital Inflammation Caused by Leishmania braziliensis.
abstract: Orbital biopsy of nonspecific orbital inflammation, commonly referred to as "orbital pseudotumor," typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of Leishmania braziliensis and DNA from the parasite.
authors: Department of Ophthalmology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil. akcruz@fmrp.usp.br aavecruz.fmrp@gmail.com.
authors: Antonio Augusto V
authors: AA
authors: Cruz
authors: Department of Cell and Molecular Biology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
authors: Eliza V C
authors: EV
authors: Alves-Ferreira
authors: Department of Ophthalmology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
authors: Gherusa
authors: G
authors: Milbratz-Moré
authors: Department of Pathology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
authors: Fernando
authors: F
authors: Chahud
authors: Department of Cell and Molecular Biology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
authors: Patricia C
authors: PC
authors: Ruy
authors: Department of Pathology, School of Medicine of University of São Paulo, Sao Paulo, Brazil.
authors: Maria Irma Seixas
authors: MI
authors: Duarte
authors: Department of Cell and Molecular Biology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil. akcruz@fmrp.usp.br aavecruz.fmrp@gmail.com.
authors: Angela Kaysel
authors: AK
authors: Cruz
mesh_terms: D000368:Aged; D006801:Humans; D007892:Leishmania braziliensis / Q000302:isolation & purification*; D008297:Male; D016727:Orbital Pseudotumor / Q000469:parasitology* / Q000473:pathology / Q000601:surgery