title: Prevalence of periprosthetic osteolysis after total hip replacement in patients with rheumatic diseases.
abstract: Periprosthetic osteolysis (PO) is a frequent complication in patients with joint implants. There are no data regarding the prevalence of PO in patients with rheumatoid arthritis (RA), juvenile chronic arthritis (JCA), ankylosing spondylitis (AS), and osteoarthritis (OA).
  
  
  OBJECTIVE
  To evaluate the prevalence of PO in patients with RA, JCA, AS, and OA, who have undergone total hip replacement (THR), and to identify factors associated with its development.
  
  
  METHODS
  The study included patients diagnosed with RA (ACR 1987), AS (modified New York criteria), JCA (European 1977 criteria), and osteoarthritis (OA) (ACR 1990 criteria) with unilateral or bilateral THR. Demographic, clinical, and therapeutic data were collected. Panoramic pelvic plain radiographs were performed, to determine the presence of PO at acetabular and femoral levels. Images were read by two independent observers.
  
  
  RESULTS
  One hundred twenty-two hip prostheses were analyzed (74 cemented, 30 cementless, and 18 hybrids). The average time from prosthesis implantation to pelvic radiograph was comparable among groups. PO was observed in 72 hips (59%). In 55% of cases, PO was detected on the femoral component, with a lower prevalence in RA (53%) vs AS (64.7%) and JCA (76.5%). Acetabular PO was more frequent in JCA patients (58.8%), compared with RA (11.6%) and OA (28.5%) patients (P= 0.0001 andP= 0.06, respectively). There was no significant association between the presence of PO and clinical, functional, or therapeutic features.
  
  
  CONCLUSIONS
  The prevalence of PO was 59%, being more frequent at the femoral level. Larger studies must be carried out to determine the clinical significance of radiologic PO.
authors: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors: Rodolfo
authors: R
authors: Perez Alamino
authors: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors: Carolina
authors: C
authors: Casellini
authors: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors: Andrea
authors: A
authors: Baňos
authors: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors: Emilce Edith
authors: EE
authors: Schneeberger
authors: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors: Susana Alicia
authors: SA
authors: Gagliardi
authors: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors: José Antonio
authors: JA
authors: Maldonado Cocco
authors: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors: Gustavo
authors: G
authors: Citera
keywords: ankylosing spondylitis; hip prosthesis; juvenile chronic arthritis; periprosthetic osteolysis; rheumatoid arthritis