title: Long-Term Survival of Primary Intracranial Plasmablastic Lymphoma: Case Report and Review of the Literature.
abstract: BACKGROUND
  Primary intracranial plasmablastic lymphoma (PIPBL) is a rare malignant tumor.
  
  
  METHODS
  We present a case of PIPBL in a 32-year-old man who complained of a progressive growing, painful mass on the right parieto-occipital part of head. Computed tomography and magnetic resonance imaging revealed a homogeneously enhanced mass with partial bone destruction. The patient underwent total resection and cranioplasty in one stage. Histopathologic examination showed large tumor cells with immunoblast-like nuclei. Immunohistochemical staining displayed CD38(+), CD138(+), Mum-1(+), CD20(-), and PAX-5(-). The patient received chemotherapy. The patient has survived more than 3.5 years after operation, with follow-up. We also review the clinical data, molecular pathologic traits, treatment, and prognosis of additional 6 cases with PIPBL in the literature.
  
  
  CONCLUSIONS
  This study provides important clinical information for the diagnosis and treatment of PIPBL.
authors: Department of Pharmacology, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, PR China.
authors: Hui
authors: H
authors: Ma
authors: Department of Neurosurgery, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, PR China.
authors: Ming-Hai
authors: MH
authors: Wei
authors: Department of Pathology, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, PR China.
authors: Hua-Min
authors: HM
authors: Qin
authors: Department of Neurosurgery, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, PR China.
authors: Guan-Yu
authors: GY
authors: Wang
authors: Department of Neurosurgery, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, PR China. Electronic address: huzengchun@hotmail.com.
authors: Zeng-Chun
authors: ZC
authors: Hu
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D000069293:Plasmablastic Lymphoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D015996:Survival Rate
keywords: Intracranial; Plasmablastic lymphoma; Prognosis; Therapy