title: Capsular Switching and Other Large-Scale Recombination Events in Invasive Sequence Type 1 Group B Streptococcus.
abstract: We report several cases of recombination events leading to capsular switching among sequence type (ST) 1 group B Streptococcus strains. These strains otherwise shared a common genome backbone with serotype V ST1 strains. However, the genomes of ST1 serotype V strains and those of serotypes VI, VII, and VIII strains differed substantially.
authors: Alefiya
authors: A
authors: Neemuchwala
authors: Sarah
authors: S
authors: Teatero
authors: Taryn B T
authors: TB
authors: Athey
authors: Allison
authors: A
authors: McGeer
authors: Nahuel
authors: N
authors: Fittipaldi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016667:Bacterial Capsules / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D058885:Multilocus Sequence Typing; D009864:Ontario / Q000453:epidemiology; D010802:Phylogeny; D011159:Population Surveillance; D011995:Recombination, Genetic; D065288:Serogroup; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000145:classification* / Q000235:genetics*; D000073336:Whole Genome Sequencing; D055815:Young Adult
keywords: bacteria; capsular switching; group B Streptococcus; recombination; streptococci; whole-genome sequencing