title: Synthesis of quinazolines from 2-aminobenzylamines with benzylamines and N-substituted benzylamines under transition metal-free conditions.
abstract: This work reports the synthesis of quinazolines from 2-aminobenzylamines with N-substituted benzylamines in the presence of molecular iodine. The developed methodology works smoothly under transition-metal free, additive free and solvent free conditions. The use of O2as a green oxidant makes it a greatly economical, green and sustainable protocol. Moreover, no aqueous work up is required thereby enhancing the efficiency. A series of quinazoline derivatives were synthesized successfully in good to excellent yields.
authors: Department of Chemistry, Institute of Chemical Technology (ICT), Mumbai, India. bm.bhanage@gmail.com bm.bhanage@ictmumbai.edu.in.
authors: Abhishek R
authors: AR
authors: Tiwari
authors: Bhalchandra M
authors: BM
authors: Bhanage