title: Recent Developments of Phototherapy Based on Graphene Family Nanomaterials.
abstract: Graphene-based nanomaterials have drawn abundant interest in various fields such as biomedicine in recent years. Thanks to the ultra-high surface area of single-layered graphene, higher molecular loading is obtained. In addition, easy modifications were acquired because of its ample oxygen-content functional groups. Owing to its excellent physical- chemical properties, graphene-based nanomaterials have been widely explored as novel nanovectors for disease theranostics. In this article, we gave a comprehensive review of graphenebased nanomaterials, including introduction about different members of graphene family nanomaterials (GFNs), various modifications, toxicity and biomedical applications of graphene- based derivatives. More attentions were given to phototherapy in this paper. The mechanisms of photothermal and photodynamic therapy were also offered. Finally, the prospects and challenges of the graphene-based nanomaterials were discussed in this review.
authors: Baomei
authors: B
authors: Zhang
authors: Yang
authors: Y
authors: Wang
authors: Department of Pharmacy, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
authors: Jiyong
authors: J
authors: Liu
authors: Department of Pharmaceutics, College of Pharmacy, Shandong University, 44 Wenhua Xilu, Jinan 250012, China.
authors: Guangxi
authors: G
authors: Zhai
mesh_terms: D000818:Animals; D006108:Graphite / Q000737:chemistry* / Q000633:toxicity; D006801:Humans; D050997:Nanomedicine / Q000379:methods*; D049329:Nanostructures; D010789:Phototherapy / Q000379:methods*
chemical_list: D006108:Graphite
keywords: GFNs; biomedical applications; modifications; multifunctional nanoformulations; phototherapy; toxicity