title: Resolution of Pulsatile Tinnitus after Venous Sinus Stenting in Patients with Idiopathic Intracranial Hypertension.
abstract: OBJECTIVE
  Evaluate the role of venous sinus stenting in the treatment of pulsatile tinnitus among patients with Idiopathic Intracranial Hypertension (IIH) and significant venous sinus stenosis.
  
  
  METHODS
  A written informed consent approved by the Weill Cornell institutional review board was signed and obtained from the study participants. Thirty-seven consecutive patients with IIH and venous sinus stenosis who were treated with venous sinus stenting between Jan.2012-Jan.2016 were prospectively evaluated. Patients without pulsatile tinnitus were excluded. Tinnitus severity was categorized based on "Tinnitus Handicap Inventory" (THI) at pre-stent, day-0, 1-month, 3-month, 6-month, 12-month, 18-month and 2-year follow-up. Demographics, body-mass index (BMI), pre and post VSS trans-stenotic pressure gradient were documented. Statistical analysis performed using Pearson's correlation, Chi-square analysis and Fischer's exact test.
  
  
  RESULTS
  29 patients with a mean age of 29.5±8.5 years M:F = 1:28. Median (mean) THI pre and post stenting were: 4 (3.7) and 1 (1) respectively. Median time of tinnitus resolution post VSS was 0-days. There was significant improvement of THI (Δ Mean: 2.7 THI [95% CI: 2.3-3.1 THI], p<0.001) and transverse-distal sigmoid sinus gradient (Δ Mean: -15.3 mm Hg [95% CI: 12.7-18 mm Hg], p<0.001) post-stenting. Mean follow-up duration of 26.4±9.8 months (3-44 months). VSS was feasible in 100% patients with no procedural complications. Three-patients (10%) had recurrent sinus stenosis and tinnitus at mean follow-up of 12 months (6-30 months).
  
  
  CONCLUSIONS
  Venous sinus stenting is an effective treatment for pulsatile tinnitus in patients with IIH and venous sinus stenosis.
authors: Department of Neurological surgery, Division of Interventional Neuroradiology, New York Presbyterian Hospital / Weill Cornell Medical Center, New York, New York, United States of America.
authors: Srikanth
authors: http://orcid.org/0000-0003-2863-5094
authors: S
authors: Boddu
authors: Department of Ophthalmology, New York Presbyterian Hospital / Weill Cornell Medical Center, New York, New York, United States of America.
authors: Marc
authors: M
authors: Dinkin
authors: Department of Otolaryngology, New York Presbyterian Hospital / Weill Cornell Medical Center, New York, New York, United States of America.
authors: Maria
authors: M
authors: Suurna
authors: Department of Neurological surgery, Division of Interventional Neuroradiology, New York Presbyterian Hospital / Weill Cornell Medical Center, New York, New York, United States of America.
authors: Kelly
authors: K
authors: Hannsgen
authors: Department of Neurological surgery, Division of Interventional Neuroradiology, New York Presbyterian Hospital / Weill Cornell Medical Center, New York, New York, United States of America.
authors: Xem
authors: X
authors: Bui
authors: Department of Neurological surgery, Division of Interventional Neuroradiology, New York Presbyterian Hospital / Weill Cornell Medical Center, New York, New York, United States of America.
authors: Athos
authors: A
authors: Patsalides
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D003392:Cranial Sinuses / Q000601:surgery*; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015607:Stents; D014012:Tinnitus / Q000209:etiology / Q000628:therapy*; D055815:Young Adult