title: Papillophlebitis versus paediatric venous thrombosis. A case with 46C/T polymorphism in the F12 coagulation gene.
abstract: METHODS
  An 8 year-old boy with no known diseases, with sudden loss of visual acuity (VA) in the left eye (LE).
  
  
  RESULTS
  VA 1 in right eye, and 0.1 in LE, discrete left relative afferent pupil defect (RAPD). Normal biomicroscopy. Funduscopy: congestive papilla, venous tortuosity, peripapillary haemorrhages with macular oedema in LE. The systemic study only revealed A C46Tpolymorphism in the F12 coagulation gene. He had a VA of 1 and normal funduscopy 8 months later.
  
  
  CONCLUSIONS
  Papillophlebitis is an inflammatory and non-ischaemic central retinal vein occlusion, ophthalmoscopically similar to central retinal vein thrombosis. The systemic study is essential to rule out underlying diseases.
authors: Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España. Electronic address: amparolinares_88@hotmail.com.
authors: A
authors: A
authors: Gargallo-Benedicto
authors: Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.
authors: M
authors: M
authors: Cerdà-Ibáñez
authors: Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.
authors: Á
authors: Á
authors: Olate-Pérez
authors: Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.
authors: R
authors: R
authors: Clemente-Tomás
authors: Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.
authors: I
authors: I
authors: Almor Palacios
authors: Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.
authors: J M
authors: JM
authors: Hervás Hernandis
authors: Servicio de Oftalmología, Hospital Clínico Universitario de Valencia, Valencia, España.
authors: A
authors: A
authors: Duch-Samper
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001766:Blindness / Q000209:etiology; D002648:Child; D003937:Diagnosis, Differential; D005174:Factor XII / Q000235:genetics*; D005175:Factor XII Deficiency; D006579:Heterozygote; D006801:Humans; D008297:Male; D020125:Mutation, Missense; D009898:Optic Disk / Q000098:blood supply*; D010689:Phlebitis / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D017354:Point Mutation; D031300:Retinal Vasculitis / Q000188:drug therapy / Q000235:genetics*; D012169:Retinal Vein; D020246:Venous Thrombosis / Q000175:diagnosis*
chemical_list: D000925:Anticoagulants; D005174:Factor XII
keywords: Central retinal vein occlusion; Genetic polymorphism; Oclusión vena central retina; Papillophlebitis; Papiloflebitis; Polimorfismo genético; Retinal vasculitis; Vasculitis retiniana