title: Radioguided surgery and the GOSTT concept: From pre-operative image and intraoperative navigation to image-assisted excision.
abstract: Radio-guided surgery has been developed for application in those disease scheduled for surgical management, particularly in areas of complex anatomy. This is based on the use of pre-operative scintigraphic planar, tomographic and fused SPECT/CT images, and the possibility of 3D reconstruction for the subsequent intraoperative locating of active lesions using handheld devices (detection probes, gamma cameras, etc.). New tracers and technologies have also been incorporated into these surgical procedures. The combination of visual and acoustic signals during the intraoperative procedure has become possible with new portable imaging modalities. In daily practice, the images offered by these techniques and devices combine perioperative nuclear medicine imaging with the superior resolution of additional optical guidance in the operating room. In many ways they provide real-time images, allowing accurate guidance during surgery, a reduction in the time required for tissue location and an anatomical environment for surgical recognition. All these approaches have been included in the concept known as (radio) Guided intraOperative Scintigraphic Tumour Targeting (GOSTT). This article offers a general view of different nuclear medicine and allied technologies used for several GOSTT procedures, and illustrates the crossing of technological frontiers in radio-guided surgery.
authors: Department of Nuclear Medicine, University Hospital Clínic Barcelona, Barcelona, Spain.
authors: H
authors: H
authors: Bowles
authors: Department of Nuclear Medicine, University Hospital Clínic Barcelona, Barcelona, Spain.
authors: N
authors: N
authors: Sánchez
authors: Department of Nuclear Medicine, University Hospital Clínic Barcelona, Barcelona, Spain.
authors: A
authors: A
authors: Tapias
authors: Department of Nuclear Medicine, University Hospital Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.
authors: P
authors: P
authors: Paredes
authors: Department of Nuclear Medicine, University Hospital Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.
authors: F
authors: F
authors: Campos
authors: Department of Nuclear Medicine, University Hospital of Wurzburg, Wurzburg, Germany.
authors: C
authors: C
authors: Bluemel
authors: Interventional Molecular Imaging Laboratory and Nuclear Medicine Section, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands; Department of Nuclear Medicine, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
authors: R A
authors: RA
authors: Valdés Olmos
authors: Department of Nuclear Medicine, University Hospital Clínic Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address: svidalsicart@clinic.cat.
authors: S
authors: S
authors: Vidal-Sicart
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D011300:Preoperative Care; D011877:Radionuclide Imaging; D025321:Surgery, Computer-Assisted; D055815:Young Adult
keywords: Cirugía radioguiada; GOSTT (Guided intraOperative Scintigraphic Tumour Targeting); Ganglio centinela; Hybrid imaging; Imagen híbrida; Linfogammagrafía; Lymphoscintigraphy; Radio-guided surgery; Sentinel node