title: [Neonatal use of propranolol for segmental facial hemangiomas].
abstract: BACKGROUND
  Segmental cervico facial hemangiomas are defined as those longer than 5 cm, affecting a specific facial area. These lesions can be eventually associated with the PHACE syndrome. Our aim is to propose neonatal treatment with propranolol, showing its efficacy/safety, given the scarce evidence on its neonatal use.
  
  
  METHODS
  After written informed consent, four patients with segmental facial hemangioma were treated with propranolol in the neonatal period. Adverse effects were registered during initial admission. Three of the four patients had PHACE syndrome. Propranolol was effective in 100% of patients, showing hemangioma´s involution without any adverse effect.
  
  
  CONCLUSIONS
  In our series, propranolol was effective and showed no side effects in the neonatal period. If propranolol benefits are greater than its risks, administration of the lowest effective dose is recommended, under hospital surveillance, starting shortly after diagnosis, in order to achieve improved efficacy.
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: V
authors: V
authors: Villamil
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: N A
authors: NA
authors: Méndez Aguirre
authors: Servicio de Servicio de Dermatología. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: T
authors: T
authors: Martínez Menchón
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: O
authors: O
authors: Girón Vallejo
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: M
authors: M
authors: Fernández Ibieta
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: P Y
authors: PY
authors: Reyes Ríos
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: I
authors: I
authors: Martínez Castaño
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: J
authors: J
authors: Rojas Ticona
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: A
authors: A
authors: Sánchez Sánchez
authors: Servicio de Radiodiagnóstico. Hospital Universitario Morales Meseguer. Murcia.
authors: L
authors: L
authors: Hernández Sánchez
authors: Servicio de Cirugía Pediátrica. Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.
authors: J I
authors: JI
authors: Ruiz Jiménez
keywords: Hemangioma; Neonatal; PHACE; Propranolol