title: Bioactive carbon-PEEK composites prepared by chemical surface treatment.
abstract: Polyetheretherketone (PEEK) has attracted much attention as an artificial intervertebral spacer for spinal reconstruction. Furthermore, PEEK plastic reinforced with carbon fiber has twice the bending strength of pure PEEK. However, the PEEK-based materials do not show ability for direct bone bonding, i.e., bioactivity. Although several trials have been conducted for enabling PEEK with bioactivity, few studies have reported on bioactive surface modification of carbon-PEEK composites. In the present study, we attempted the preparation of bioactive carbon-PEEK composites by chemical treatments with H2SO4and CaCl2. Bioactivity was evaluated by in vitro apatite formation in simulated body fluid (SBF). The apatite formation on the carbon-PEEK composite was compared with that of pure PEEK. Both pure PEEK and carbon-PEEK composite formed the apatite in SBF when they were treated with H2SO4and CaCl2; the latter showed higher apatite-forming ability than the former. It is conjectured that many functional groups able to induce the apatite nucleation, such as sulfo and carboxyl groups, are incorporated into the dispersed carbon phase in the carbon-PEEK composites.
authors: Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Japan. Electronic address: tmiya@life.kyutech.ac.jp.
authors: Toshiki
authors: T
authors: Miyazaki
authors: Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Japan.
authors: Chisato
authors: C
authors: Matsunami
authors: Frontier Research Academy for Young Researchers, Kyushu Institute of Technology, Japan.
authors: Yuki
authors: Y
authors: Shirosaki
mesh_terms: D001577:Benzophenones; D002244:Carbon / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008422:Materials Testing / Q000379:methods*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D013464:Sulfuric Acids / Q000737:chemistry*; D014867:Water / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D001577:Benzophenones; D007659:Ketones; D011108:Polymers; D013464:Sulfuric Acids; D014867:Water; C063834:polyetheretherketone; D011092:Polyethylene Glycols; D002244:Carbon; C033158:sulfuric acid
keywords: Apatite; Bioactivity; Carbon–PEEK composite; Polyetheretherketone (PEEK); Simulated body fluid (SBF); Surface treatment