title: Quality-of-life after bile duct injury: intraoperative detection is crucial. A national case-control study.
abstract: Existing reports on quality-of-life (QoL) after bile duct injury (BDI) are conflicting.
  
  
  
  Case-control study were QoL assessment was performed using SF-36 (36-item short Form health survey). Patients with BDI were compared to a matched control group (1:2) subject to cholecystectomy.
  
  
  
  In total 168 BDIs (0.3%) were eligible for participation and 64% returned SF-36. Median follow-up was 4.3 years. Intraoperative cholangiography was performed/attempted in 93% of BDI patients and 92% were diagnosed intraoperatively. Lesions <5 mm dominated (59%) and QoL was comparable for BDIs and controls (physical composite score PCS; p = 0.052 and mental composite score MCS; p = 0.478). Patients with an immediate intraoperative repair reported a better PCS than patients subjected to a later repair and/or referral (p = 0.002). No difference in SF-36 was detected when the BDI was repaired by the index compared to non-index surgeon (PCS p = 0.446, MCS p = 0.525).
  
  
  
  QoL after bile duct injury is comparable to uneventful cholecystectomy, as long as the injury is diagnosed intraoperatively. Immediate repair, in this cohort of mainly minor injuries, also performed by the index surgeon, resulted in similar QoL as in the control group. We suggest liberal use of cholangiography for early detection of BDI, and intraoperative repair whenever possible.
authors: Department of Surgery, Clinical Sciences, Lund University, Sweden. Electronic address: jenny.rystedt@med.lu.se.
authors: Jenny M L
authors: JM
authors: Rystedt
authors: Department of Surgery, Clinical Sciences, Lund University, Sweden.
authors: Agneta K
authors: AK
authors: Montgomery
mesh_terms: D000328:Adult; D000368:Aged; D001652:Bile Ducts / Q000000981:diagnostic imaging / Q000293:injuries* / Q000601:surgery; D016022:Case-Control Studies; D002763:Cholecystectomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011788:Quality of Life; D012042:Registries; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013548:Sweden; D013997:Time Factors; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000000981:diagnostic imaging / Q000209:etiology* / Q000523:psychology / Q000601:surgery