title: An Investigation of Antibacterial Resistance Patterns AmongAcinetobacter baumanniiandPseudomonas aeruginosaIsolates Collected from Intensive Care Units of a University-Affiliated Hospital in Ahvaz, Iran.
abstract: BACKGROUND
  In recent decades, multidrug-resistant non-fermenting Gram-negative pathogens, particularlyAcinetobacter baumanniiandPseudomonas aeruginosa, have been recognized as a major cause of healthcare-associated and nosocomial infections and outbreaks.
  
  
  OBJECTIVE
  The aim of this study was to determine the prevalence and pattern of antibiotic resistance inA. baumanniiandP. aeruginosaisolates collected from intensive care units (ICUs).
  
  
  METHODS
  One hundred fifty-five clinical isolates, including 80 (51.6%) isolates ofA. baumanniiand 75 (48.4%) isolates ofP. aeruginosa, from hospitalized patients in the ICUs of a teaching hospital in Ahvaz, Iran, were collected from January 1 to December 30, 2013. The organisms were identified with conventional bacteriological methods, and antimicrobial susceptibility testing was performed on all isolates in accordance with clinical laboratory and standards institute (CLSI) guidelines.
  
  
  RESULTS
  The maximum resistance rates amongA. baumanniiisolates were observed for ciprofloxacin and trimethoprim-sulfamethoxazole (96.9% and 95.2%, respectively). ForP. aeruginosaisolates, the maximum resistance rates were reported for ceftriaxone and trimethoprim-sulfamethoxazole (97.2% and 92.4%, respectively).
  
  
  CONCLUSIONS
  The majority ofA. baumanniiandP. aeruginosaisolates were found to be resistant to commonly recommended antibiotics. Therefore, surveillance of antibiotic consumption and proper antibiotic administration guidelines are essential for preventing major outbreaks in the future.
authors: Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Farrokh
authors: F
authors: Izadpour
authors: Department of Pathology, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Nastaran
authors: N
authors: Ranjbari
authors: Neonatal Intensive Care Unit (NICU), Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Mohammad-Reza
authors: MR
authors: Aramesh
authors: Health Research Institute, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran; Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Mojtaba
authors: M
authors: Moosavian
authors: Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran; School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Shiva
authors: S
authors: ShahAli
authors: Department of Pathology, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Farzaneh
authors: F
authors: Larki
authors: Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Hamed
authors: H
authors: Tabesh
authors: Department of Pathology, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Afrooz
authors: A
authors: Morvaridi
keywords: Acinetobacter baumannii; Intensive Care Unit; Pseudomonas aeruginosa; Resistance; Susceptibility