title: An initial waitlist-controlled trial of the unified protocol for the treatment of emotional disorders in adolescents.
abstract: A substantial proportion of adolescents are non-responders to well-established treatments for anxiety and depression, and many existent approaches do not adequately address comorbidity. There is a need to develop and evaluate unified treatments for adolescents that flexibly address higher order factors shared among internalizing or emotional disorders. The Unified Protocol for the Treatment of Emotional Disorders in Adolescents (UP-A) is a transdiagnostic treatment that targets shared vulnerability and maintenance factors in a flexible format. This study examined initial outcomes of a randomized, waitlist-controlled trial of the UP-A. The UP-A outperformed waitlist at mid-treatment with respect to disorder severity and functional impairment, and there was a significant treatment effect in favor of the UP-A on all outcome measures at post-treatment. Within-subjects analyses collapsing across participants revealed significant improvements on outcome measures over time. Results support further study of the UP-A and its potential efficacy in treating adolescent anxiety and depression.
authors: University of Miami, Department of Psychology, 5665 Ponce de Leon Blvd, Flipse Building, Room 315, Coral Gables, FL 33146, United States. Electronic address: j.ehrenreich@miami.edu.
authors: Jill
authors: J
authors: Ehrenreich-May
authors: Southern Methodist University, Department of Psychology, PO Box 750442, Dallas, TX 75275-0442, United States. Electronic address: drosenfi@mail.smu.edu.
authors: David
authors: D
authors: Rosenfield
authors: Tufts University, Department of Psychology, 490 Boston Avenue, Medford, MA 02155, United States. Electronic address: Alexander.Queen@tufts.edu.
authors: Alexander H
authors: AH
authors: Queen
authors: University of Miami, Department of Psychology, 5665 Ponce de Leon Blvd., Flipse Building, Coral Gables, FL 33146, United States. Electronic address: s.kennedy2@miami.edu.
authors: Sarah M
authors: SM
authors: Kennedy
authors: University of Miami, Department of Psychology, 5665 Ponce de Leon Blvd., Flipse Building, Coral Gables, FL 33146, United States. Electronic address: cara.remmes@gmail.com.
authors: Cara S
authors: CS
authors: Remmes
authors: Boston University, Center for Anxiety and Related Disorders, 648 Beacon Street, Boston, MA 02215, United States. Electronic address: dhbarlow@bu.edu.
authors: David H
authors: DH
authors: Barlow
mesh_terms: D000293:Adolescent; D001007:Anxiety / Q000523:psychology / Q000628:therapy; D001008:Anxiety Disorders / Q000523:psychology / Q000628:therapy*; D002648:Child; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003863:Depression / Q000523:psychology / Q000628:therapy; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D016896:Treatment Outcome
keywords: Adolescent; Anxiety; CBT; Depression; Transdiagnostic