Confined Growth of Metal Nanoparticles Within 3D DNA Origami Molds.
Manufacturing prescribed shaped metal nanoparticles promises emerging applications in plasmonics, energy, and disease diagnosis. The key to the shape-controllable synthesis is generating local environments encoded with prescribed geometrical information. Here, we describe a general strategy that uses 3D self-assembled DNA origami as mold to confine the casting growth of metal nanoparticle. By transferring the shape information from DNA cavities to metal nanoparticles, metal nanoparticles with prescribed shapes, dimensions, and surface binding features could be rationally designed and synthesized.
Wyss Institute for Biologically Inspired Engineering, Harvard University, CLSB 5th Floor, 3 Blackfan Circle, Boston, MA, 02115, USA. wei_sun@hms.harvard.edu.|Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA. wei_sun@hms.harvard.edu.
Wei
W
Sun
Wyss Institute for Biologically Inspired Engineering, Harvard University, CLSB 5th Floor, 3 Blackfan Circle, Boston, MA, 02115, USA.|Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA.
Jie
J
Shen
D004247:DNA / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods
D004247:DNA
Confined growth; DNA origami; Metal nanoparticle