[Cancer in adolescents and young adults in France: Epidemiology and pathways of care].
In adolescents and young adults (AYA), cancers are rare but represent the third significant cause of death. The aim of this paper was to investigate epidemiological data and pathways of care of AYA in France. During the 2000-2008 period, overall age-standardized incidence rates (ASR) were 254.1/106in 15-24-year-olds. The most frequently diagnosed cancers in male AYA were malignant gonadal germ-cell tumors and Hodgkin's lymphoma, and were melanoma, thyroid carcinoma and Hodgkin's disease in females. The ASR appeared stable over time. During the 2000-2004 period, the 5-year overall survival for all cancers was 81.8%, with differences between genders and age groups: 78.8% for males and 85.2% for females; 78.5% in 15-19-year-olds and 84.3% in 20-24-year-olds. Survival has significantly improved over time. During the 2006-2007 period, the pathways of care for French adolescent patients with cancer were heterogeneous: 82% were treated in an adult environment, 27% were included in clinical studies, and in 54% of cases the management decisions were taken in the context of a multidisciplinary team. Studies looking at management of AYA with cancer have shown a wide disparity and a lack of collaboration between adult oncologists and pediatric oncologist. An AYA cancer multidisciplinary interest group has been created to determine priorities and coordinate efforts to improve AYA cancer services and care.
CHU de Nancy, Registre national des tumeurs solides de l'enfant, Registre national des cancers de l'enfant, 54500 Vandœuvre-lès-Nancy, France; Université de Paris-Sorbonne, Inserm UMRS-1153, CRESS team 7, 75006 Paris, France. Electronic address: emmanuel.desandes@univ-lorraine.fr.
Emmanuel
E
Desandes
CHU de Nancy, Registre national des tumeurs solides de l'enfant, Registre national des cancers de l'enfant, 54500 Vandœuvre-lès-Nancy, France; Université de Paris-Sorbonne, Inserm UMRS-1153, CRESS team 7, 75006 Paris, France.
Brigitte
B
Lacour
Université de Paris-Sorbonne, Inserm UMRS-1153, CRESS team 7, 75006 Paris, France; Registre national des hémopathies de l'enfant, Registre national des cancers de l'enfant, 94805 Villejuif, France.
Jacqueline
J
Clavel
Faculté de médecine, Réseau français des registres de cancers (FRANCIM), 31000 Toulouse, France.
D000293:Adolescent; D017677:Age Distribution; D000367:Age Factors; D019091:Critical Pathways / Q000458:organization & administration; D019468:Disease Management; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D009369:Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy*; D010348:Patient Care Team; D012042:Registries / Q000706:statistics & numerical data; D017678:Sex Distribution; D013997:Time Factors; D055815:Young Adult
Adolescents; Cancer; Epidemiology; Jeunes adultes; Parcours de soins; Pathways of care; Young adults cancer; Épidémiologie