Takayasu arteritis (TA) first presenting with intestinal ischemia: a case report and review of gastrointestinal tract involvement (ischemic and non-ischemic) associated with TA.
Takayasu arteritis (TA) is a large vessel vasculitis involving the aorta and its major branches. Insidious inflammation usually results in gradual arterial narrowing; however, critical organ ischemia is rare. We describe a young male with TA who presented with acute mesenteric ischemia requiring intestinal resection, followed by critical limb ischemia. In our literature review, we identified intestinal gangrene as a rare manifestation of TA. However, intestinal ischemia as the first manifestation of TA has been scarcely reported in the literature. Also, ischemia of the intestine occurring together with critical limb ischemia is extremely unusual. Rheumatologists should be aware of TA as a rare cause of gastrointestinal vasculitis in young adults, which can be easily suspected by routinely examining all the peripheral pulses.
Department of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India. durgapmisra@gmail.com.
Durga Prasanna
DP
Misra
Department of Radiodiagnosis, JIPMER, Puducherry, 605006, India.
Nagarajan
N
Krishnan
Department of Pathology, JIPMER, Puducherry, 605006, India.
Debasis
D
Gochhait
Department of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.
Dantis
D
Emmanuel
Department of Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.
Vir Singh
VS
Negi
D000328:Adult; D041981:Gastrointestinal Tract / Q000000981:diagnostic imaging; D006801:Humans; D007422:Intestines / Q000098:blood supply* / Q000000981:diagnostic imaging; D007511:Ischemia / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D013625:Takayasu Arteritis / Q000150:complications* / Q000000981:diagnostic imaging
Gangrene; Gastrointestinal tract; Mesenteric ischemia; Takayasu arteritis