Treatment Duration After Acute Symptomatic Seizures in Neonates: A Multicenter Cohort Study.
We aimed to define determinants of duration of treatment for acute symptomatic neonatal seizures in a contemporary multicenter observational cohort study. After adjustment for potential confounders, only study site and seizure etiology remained significantly associated with the chance of continuing antiseizure medication after discharge to home.
Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI. Electronic address: shellhaa@med.umich.edu.
Renée A
RA
Shellhaas
Department of Neurology, Children's National Health System, George Washington University School of Medicine, Washington, DC.
Taeun
T
Chang
Departments of Neurology and Pediatrics, Stanford University, Palo Alto, CA.
Courtney J
CJ
Wusthoff
Department of Neurology, Boston Children's Hospital, Boston, MA.
Janet S
JS
Soul
Departments of Neurology and Pediatrics, The Perelman School of Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.
Shavonne L
SL
Massey
Department of Neurology, Massachusetts General Hospital, Boston, MA.
Catherine J
CJ
Chu
Departments of Neurology and Pediatrics, University of California San Francisco Benioff Children's Hospital, University of California San Francisco, San Francisco, CA.
M Roberta
MR
Cilio
Departments of Neurology and Pediatrics, Stanford University, Palo Alto, CA.
Sonia L
SL
Bonifacio
Departments of Neurology and Pediatrics, The Perelman School of Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.
Nicholas S
NS
Abend
Department of Neurology, Children's National Health System, George Washington University School of Medicine, Washington, DC.
Tammy N
TN
Tsuchida
Departments of Neurology and Pediatrics, University of California San Francisco Benioff Children's Hospital, University of California San Francisco, San Francisco, CA; Department of Epidemiology and Biostatistics; University of California San Francisco, San Francisco, CA.
Hannah C
HC
Glass
D000927:Anticonvulsants / Q000627:therapeutic use*; D015331:Cohort Studies; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011446:Prospective Studies; D012042:Registries; D012640:Seizures / Q000188:drug therapy* / Q000209:etiology; D013997:Time Factors
D000927:Anticonvulsants
EEG; critical care; electroencephalogram; epilepsy; hypoxic-ischemic encephalopathy; infant; neonatal encephalopathy; neonatal seizures; neurocritical care