Cytomegalovirus-induced collapsing focal segmental glomerulosclerosis.
Collapsing glomerulopathy is an aggressive morphologic variant of focal segmental glomerulosclerosis which typically presents with nephrotic syndrome and rapidly progressive renal failure. Most cases of collapsing glomerulopathy are associated with human immunodeficiency virus infection. We present a rare case of collapsing glomerulopathy associated with acute cytomegalovirus (CMV) infection in an immunocompetent host with improvement in renal function after the treatment of CMV with ganciclovir. CMV may be an under-recognized cause of collapsing glomerulopathy which may respond to antiviral treatment.
Department of Medicine , North Shore-LIJ Health Care System-Lenox Hill Hospital , New York, NY , USA.
Vanya
V
Grover
Department of Nephrology , North Shore-LIJ Health Care System-Lenox Hill Hospital , New York, NY , USA.
Meghana R
MR
Gaiki
Department of Nephrology , North Shore-LIJ Health Care System-Lenox Hill Hospital , New York, NY , USA.
Maria V
MV
DeVita
Department of Nephrology , North Shore-LIJ Health Care System-Lenox Hill Hospital , New York, NY , USA.
Joshua A
JA
Schwimmer
collapsing glomerulopathy; cytomegalovirus infection; focal segmental glomerulosclerosis