Comparison of three monocular methods for measuring accommodative stimulus-response curves.
OBJECTIVE
The aim was to evaluate the repeatability of dynamic measurement of the accommodative stimulus-response curve (ASRC) at three different dioptric speeds using a modified instrument and its agreement with two other methods.


METHODS
Twenty-nine adults (23.5 ± 2.0 years) were enrolled in the study. ASRC was measured monocularly using three methods: dynamic and static measurement using a motorised Badal system mounted on an open-field auto-refractor (WAM-5500, Grand Seiko Co., Ltd, Japan) and the minus lens technique. Dynamic measurements were conducted at three dioptric stimulus speeds to simulate continuous stimuli for ASRC (0.25, 0.40 and 0.55 D/s), with three repetitions for each speed. All three types of ASRCs were fitted with third-degree polynomial equations. The slope and objective accommodative amplitude of the ASRC were analysed.


RESULTS
The repeatability of objective accommodative amplitude worsened as the speed of the stimuli increased. The repeatability of the slope was best at a speed of 0.40 D/s and worst at 0.55 D/s. The measurement method significantly influenced the objective accommodative amplitude values and slope (both, p < 0.001). The minus lens technique yielded the highest amplitude of accommodation (6.21 ± 0.84 D) and steepest slope (1.11 ± 0.14), followed by the static Badal method (5.60 ± 0.83 D and 0.89 ± 0.09 D). The objective accommodative amplitude decreased with increasing speed during dynamic measurements. There was no difference between the slopes at 0.25 D and 0.40 D/s (p > 0.05) and the slope was lowest at 0.55 D/s.


CONCLUSIONS
The accommodative stimulus-response curve values are method-dependent and the significant differences between three methods used to determine the ASRC based on slope and accommodative amplitude indicate that these methods are non-interchangeable. Using dynamic measurements, accommodative behaviour varies with the speed of dioptric-change of the stimulus. A speed of 0.40 D/s appears to be the best compromise in terms of time, results and repeatability for dynamic ASRC measurement.
School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.|WEIRC, WMU-Essilor International Research Centre, Wenzhou, Zhejiang, China.
Yunyun
Y
Chen
School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.|WEIRC, WMU-Essilor International Research Centre, Wenzhou, Zhejiang, China.
Wanqing
W
Jin
School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhili
Z
Zheng
School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.|WEIRC, WMU-Essilor International Research Centre, Wenzhou, Zhejiang, China.
Chuanchuan
C
Zhang
School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.|WEIRC, WMU-Essilor International Research Centre, Wenzhou, Zhejiang, China.
Huiling
H
Lin
WEIRC, WMU-Essilor International Research Centre, Wenzhou, Zhejiang, China.|R&D Optics Asia, Essilor International, Wenzhou, Zhejiang, China.
Björn
B
Drobe
School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.|WEIRC, WMU-Essilor International Research Centre, Wenzhou, Zhejiang, China.
Jinhua
J
Bao
School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.|WEIRC, WMU-Essilor International Research Centre, Wenzhou, Zhejiang, China.
Hao
H
Chen
D000065:Accommodation, Ocular; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D055815:Young Adult
accommodation; accommodative stimulus-response curve; objective accommodative amplitude; repeatability; slope