Migraine and Mental Health in a Population-Based Sample of Adolescents.
OBJECTIVE
To explore the relationship between migraine and anxiety disorders, mood disorders and perceived mental health in a population-based sample of adolescents.


METHODS
The Canadian Community Health Survey (CCHS) is a cross-sectional health survey sampling a nationally representative group of Canadians. In this observational study, data on all 61,375 participants aged 12-19 years from six survey cycles were analyzed. The relationships between self-reported migraine, perceived mental health, and mood/anxiety disorders were modeled using univariate and multivariate logistic regression. The migraine-depression association was also explored in a subset of participants using the Composite International Diagnostic Interview-Short Form (CIDI-SF) depression scale.


RESULTS
The odds of migraine were higher among those with mood disorders, with the strongest association in 2011-2 (adjusted odds ratio [aOR]=4.59; 95% confidence interval [CI 95%]=3.44-6.12), and the weakest in 2009-10 (aOR=3.06, CI 95%=2.06-4.55). The migraine-mood disorders association was also significant throughout all cycles, other than 2011-2, when the CIDI-SF depression scale was employed. The odds of migraine were higher among those with anxiety disorders, with the strongest association in 2011-2 (aOR=4.21, CI 95%=3.31-5.35) and the weakest in 2010 (aOR=1.87, CI 95%=1.10-3.37). The inverse association between high perceived mental health and the odds of migraine was observed in all CCHS cycles, with the strongest association in 2011-2 (aOR=0.58, CI 95%=0.48-0.69) and the weakest in 2003-4 (aOR=0.75, CI 95%=0.62-0.91).


CONCLUSIONS
This study provides evidence, derived from a large population-based sample of adolescents, for a link between migraine and mood/anxiety disorders.
1Department of Public Health and Preventive Medicine,School of Epidemiology,University of Ottawa,Ottawa,Ontario,Canada.
Serena L
SL
Orr
1Department of Public Health and Preventive Medicine,School of Epidemiology,University of Ottawa,Ottawa,Ontario,Canada.
Beth K
BK
Potter
1Department of Public Health and Preventive Medicine,School of Epidemiology,University of Ottawa,Ottawa,Ontario,Canada.
Jinhui
J
Ma
1Department of Public Health and Preventive Medicine,School of Epidemiology,University of Ottawa,Ottawa,Ontario,Canada.
Ian
I
Colman
D000293:Adolescent; D002170:Canada / Q000453:epidemiology; D018672:Community Health Planning; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D016015:Logistic Models; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology*; D008603:Mental Health; D008881:Migraine Disorders / Q000453:epidemiology* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012111:Residence Characteristics
Anxiety; adolescents; anxiety disorders; depression; headache; migraine; mood disorders