Predisposing factors for pancreatic adenocarcinoma: What is the role of imaging?
Early detection of pancreatic adenocarcinoma is the goal of imaging, enabling curative surgery. The identification of high-grade dysplastic precursor lesions is even more beneficial. Two forms are now better known: pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasm (IPMN). To detect these lesions with imaging, we need to know the patterns associated with them. A screening program could then be used to pinpoint them. This program could not be applied to the entire population. Identifying patients with an increased risk of pancreas adenocarcinoma is the first step of such screening.
Radiology Department, Beaujon Hospital, 100, boulevard General-Leclerc, 92110 Clichy, France. Electronic address: marie-pierre.vullierme@aphp.fr.
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Vullierme
Radiology Department, Beaujon Hospital, 100, boulevard General-Leclerc, 92110 Clichy, France.
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Lagadec
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000453:epidemiology*; D065311:Adenocarcinoma in Situ / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology*; D021441:Carcinoma, Pancreatic Ductal / Q000000981:diagnostic imaging / Q000453:epidemiology*; D015984:Causality; D002760:Cholangiopancreatography, Endoscopic Retrograde; D049448:Cholangiopancreatography, Magnetic Resonance; D019983:Guideline Adherence; D006801:Humans; D008279:Magnetic Resonance Imaging; D008403:Mass Screening; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011230:Precancerous Conditions / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology*; D014057:Tomography, X-Ray Computed
CT; IPMN; MRI; PanIN; Pancreas adenocarcinoma