Plant SnRK1 Kinases: Structure, Regulation, and Function.
SnRK1 is an evolutionarily conserved protein kinase complex that regulates energy homeostasis in plants. In doing so, it promotes tolerance to adverse environmental conditions and influences a large array of growth and developmental processes. SnRK1 shares clear structural and functional similarities with its orthologs, yeast SNF1 and mammalian AMPK, but has evolved unique features that presumably provide a better adaptation to an autotrophic lifestyle. In this chapter, we review current knowledge on SnRK1, an atypical member of the SNF1/AMPK family, providing insight into its structure, regulation, and functions.
Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156, Oeiras, Portugal.
Leonor
L
Margalha
Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156, Oeiras, Portugal.
Concetta
C
Valerio
Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156, Oeiras, Portugal. ebaena@igc.gulbenkian.pt.
Elena
E
Baena-González
D000222:Adaptation, Physiological / Q000235:genetics; D017360:Arabidopsis / Q000201:enzymology / Q000235:genetics*; D029681:Arabidopsis Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D004734:Energy Metabolism / Q000235:genetics; D018506:Gene Expression Regulation, Plant; D006706:Homeostasis; D010766:Phosphorylation; D055503:Protein Multimerization; D011499:Protein Processing, Post-Translational; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D021122:Protein Subunits / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D058207:Sumoylation; D054875:Ubiquitination
D029681:Arabidopsis Proteins; D017346:Protein Serine-Threonine Kinases; D021122:Protein Subunits; C531469:At3g01090 protein, Arabidopsis
Carbon allocation; Carbon metabolism; Energy signaling; Homeostasis; Plant; SNF1-related protein kinase (SnRK1); Stress