Near-Infrared Fluorescence-Enhanced Optical Tomography.
Fluorescence-enhanced optical imaging using near-infrared (NIR) light developed forin vivomolecular targeting and reporting of cancer provides promising opportunities for diagnostic imaging. The current state of the art of NIR fluorescence-enhanced optical tomography is reviewed in the context of the principle of fluorescence, the different measurement schemes employed, and the mathematical tools established to tomographically reconstruct the fluorescence optical properties in various tissue domains. Finally, we discuss the recent advances in forward modeling and distributed memory parallel computation to provide robust, accurate, and fast fluorescence-enhanced optical tomography.
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA.
Banghe
0000-0002-8870-1455
B
Zhu
Optical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL 33174, USA.
Anuradha
0000-0002-6094-5909
A
Godavarty
D005453:Fluorescence; D006801:Humans; D008962:Models, Theoretical; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D041622:Tomography, Optical / Q000379:methods*