Human meningitis due to Streptococcus suis in Lomé, Togo: a case report.
Streptococcus suis is a zoonotic pathogen which represents the leading cause of meningitis in Southeast Asia and an emerging pathogen in the Western world, the main risk factor for infection being contact with pigs. In Africa, the prevalence of S. suis infections in swine and humans is largely unrecognized, with only one recent report of a limited case series.



We describe a human case of meningitis due to S. suis in a 32-year-old man living in Togo. The patient had no particular medical history and no risk factors for immunodeficiency but reported regular contact with pork products. Using specific immunological and molecular methods, we characterized the isolate as S. suis serotype 2, ST1, one the most prevalent and virulent clone worldwide. The outcome was favorable after one week of adapted antibiotic therapy but the patient was left with severe hearing disorders.



This work highlights the emergence of this pathogen in Africa and reinforces the need for accurate epidemiological and surveillance studies of S. suis infections and for educating clinicians and exposed groups in non-endemic countries.
Centre de Biologie Moléculaire et d'Immunologie, Université de Lomé, BP 101, Lomé, Togo.|Service de Microbiologie, Centre Hospitalier Universitaire Sylvanus Olympio, Tokoin Hôpital, BP 57, Lomé, Togo.
Mireille
M
Prince-David
Centre de Biologie Moléculaire et d'Immunologie, Université de Lomé, BP 101, Lomé, Togo.|Service de Microbiologie, Centre Hospitalier Universitaire Sylvanus Olympio, Tokoin Hôpital, BP 57, Lomé, Togo.
Mounerou
M
Salou
Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, 22440, Ploufragan, France.|Université Bretagne Loire, 22440, Ploufragan, France.
Corinne
C
Marois-Créhan
Service de Neurologie, Centre Hospitalier Universitaire Campus, BP 30284, Lomé, Togo.
Komi
K
Assogba
Service de Bactériologie, Hôpitaux Universitaires Paris Centre, site Cochin, 75679, Paris cedex 14, France.|Centre National de Référence des Streptocoques, Hôpital Cochin, 75679, Paris cedex 14, France.
Céline
C
Plainvert
Service de Neurologie, Centre Hospitalier Universitaire Campus, BP 30284, Lomé, Togo.
Koffi A
KA
Balogou
Service de Bactériologie, Hôpitaux Universitaires Paris Centre, site Cochin, 75679, Paris cedex 14, France.|Centre National de Référence des Streptocoques, Hôpital Cochin, 75679, Paris cedex 14, France.|Université Paris Descartes, 75006, Paris, France.
Claire
C
Poyart
Service de Bactériologie, Hôpitaux Universitaires Paris Centre, site Cochin, 75679, Paris cedex 14, France. asmaa.tazi@cch.aphp.fr.|Centre National de Référence des Streptocoques, Hôpital Cochin, 75679, Paris cedex 14, France. asmaa.tazi@cch.aphp.fr.|Université Paris Descartes, 75006, Paris, France. asmaa.tazi@cch.aphp.fr.
Asmaa
0000-0001-9531-9177
A
Tazi
D000328:Adult; D000818:Animals; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D000069466:Red Meat / Q000382:microbiology; D065288:Serogroup; D013290:Streptococcal Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D017011:Streptococcus suis / Q000302:isolation & purification / Q000472:pathogenicity*; D013552:Swine; D014012:Tinnitus / Q000188:drug therapy / Q000209:etiology; D014037:Togo
Capsular serotype; Case report; Meningitis; Neurologic sequelae; Streptococcus suis; Zoonosis