Rare cause of acute hepatitis: a common energy drink.
A previously healthy man aged 50 years presented with malaise, anorexia, abdominal pain, nausea, vomiting, generalised jaundice, scleral icterus and dark urine. He was not on any prescription or over-the-counter medications, but reported drinking 4-5 energy drinks daily for 3 weeks prior to presentation. Physical examination revealed jaundice and right upper quadrant abdominal tenderness. Laboratory studies were remarkable for transaminitis and evidence of chronic hepatitis C infection. Ultrasound scan demonstrated an echogenic liver and diffuse gallbladder wall thickening. Liver biopsy showed severe acute hepatitis with bridging necrosis and marked cholestasis. The patient was treated supportively with complete resolution of his symptoms and marked improvement in his laboratory abnormalities. The development of acute hepatitis in this patient was likely secondary to excessive energy drink consumption. Energy drinks as well as other herbal/over-the-counter supplements should be considered by clinicians in the workup of patients with acute hepatitis, particularly once other aetiologies have been excluded.
Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA.
Jennifer Nicole
JN
Harb
Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Zachary A
ZA
Taylor
Division of Gastroenterology, Hepatology, & Nutrition, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Vikas
V
Khullar
Division of General Internal Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Maryam
M
Sattari
D000208:Acute Disease; D061215:Energy Drinks / Q000009:adverse effects*; D006505:Hepatitis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged