Ocular dirofilariasis by Dirofilaria immitis in a child in Iran: A case report and review of the literature.
This report describes a rare case of ophthalmic dirofilariasis in a 2-year-old boy with redness, irritation, pain and foreign body sensation in the right eye. Slit lamp examination demonstrated a thread-like whitish nematode in the anterior chamber of the right eye that twisted around itself. The nematode worm (35mm long and 150-200μm width) was removed surgically. The presence of the smooth cuticular surface without longitudinal ridges and the vulva showed that it could be a female Diroflaria immitis. PCR amplification was done to verify the Diroflaria species. PCR amplification and sequence analysis of mitochondrial 12S rDNA confirmed that recovered worm was D. immitis. Ocular dirofilariasis caused by D. immitis is very rare, but it must be considered in humans living in endemic areas.
Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran; Department of Parasitology and Mycology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Hadi
H
Mirahmadi
Al-Zahra Eye Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Alireza
A
Maleki
Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Raheleh
R
Hasanzadeh
Department of Parasitology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Mohammad Bagher
MB
Ahoo
Department of Parasitology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Iraj
I
Mobedi
Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Students Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: Alirostami1984@gmail.com.
Ali
A
Rostami
D000818:Animals; D000867:Anterior Chamber / Q000469:parasitology; D002675:Child, Preschool; D004275:DNA, Ribosomal; D004183:Dirofilaria immitis / Q000235:genetics / Q000302:isolation & purification*; D004184:Dirofilariasis / Q000175:diagnosis / Q000469:parasitology*; D015822:Eye Infections, Parasitic / Q000175:diagnosis / Q000469:parasitology*; D006801:Humans; D007492:Iran; D008297:Male; D016133:Polymerase Chain Reaction; D000072776:Slit Lamp Microscopy
D004275:DNA, Ribosomal
Diroflaria immitis; Iran; Ocular dirofilariasis