Comparison of power Doppler and thermography for the selection of thyroid nodules in which fine-needle aspiration biopsy is indicated.
OBJECTIVE
To compare two methods-power Doppler and thermography-for the analysis of nodule vascularization and subsequent selection of nodules to be biopsied.


METHODS
A total of 510 subjects with thyroid nodules were analyzed by power Doppler and submitted to fine-needle aspiration biopsy (FNAB). Thirty-seven patients were submitted to nodule excision (29 due to carcinoma or suspected carcinoma and 8 by patient choice). Among those patients, power Doppler had raised the suspicion of malignancy in 39 lesions, compared with 48 for FNAB. Another group, comprising 110 patients, underwent thermography, which raised the suspicion of malignancy in 124 thyroid nodules, as did FNAB. Malignant nodules were excised in all 110 of those patients (95 underwent nodulectomy and 15 underwent thyroidectomy), malignancy being confirmed by intraoperative examination of frozen biopsy samples.


RESULTS
In relation to the FNAB findings, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of power Doppler were 95.16%, 23.52%, 96.22%, 16.70%, and 89.51%, respectively, compared with 100%, 58.06%, 87.73%, 100%, and 89.51%, respectively, for thermography.


CONCLUSIONS
Thermography was more precise than was power Doppler for the selection of thyroid nodules to be biopsied.
PhD, Professor of Medicine at the Universidade de Ribeirão Preto (Unaerp), Ribeirão Preto, SP, Brazil.
Maria Lucia D'Arbo
ML
Alves
Doctoral Student in Environmental Technology, Professor of Engineering at the Universidade de Ribeirão Preto (Unaerp), Ribeirão Preto, SP, Brazil.
Manoel Henrique Cintra
MH
Gabarra
Thermography; Thyroid gland; Thyroid nodule/blood supply; Ultrasonography, Doppler