Codon optimality and mRNA decay.
Recent evidence indicates that codon optimality is a broad determinant of mRNA stability. A study by Radhakrishnan et al. in Cell raises the possibility that the conserved DEAD-box protein Dhh1 underlies the phenomenon.
Department of Chemistry and Biochemistry, University of Colorado Boulder, Boulder, CO 80303, USA.|Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, CO 80303, USA.
Yuriko
Y
Harigaya
Department of Chemistry and Biochemistry, University of Colorado Boulder, Boulder, CO 80303, USA.|Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, CO 80303, USA.
Roy
R
Parker
D003062:Codon; D011506:Proteins; D020871:RNA Stability; D012333:RNA, Messenger
D003062:Codon; D011506:Proteins; D012333:RNA, Messenger