Low cardiac output thyroid storm in a girl with Graves' disease.
A 15-year-old girl with Graves' disease presented with hypotension after methimazole and propranolol were re-started for hyperthyroidism. She was found to have pulmonary artery hypertension resulting in obstructive shock. Thyroid storm was diagnosed according to Burch and Wartofsky score. She was promptly treated with anti-thyroid drugs, inorganic iodide, corticosteroid, and respiratory support. Pulmonary hypertension was treated with inhaled nitric oxide until the clinical status improved. Propranolol was withdrawn due to poor cardiac function. We herein present a unique case of a difficult-to-treat Graves' disease presenting with severe pulmonary hypertension resulting in low cardiac output thyroid storm.
Division of Critical Care Medicine, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. marut.cha@mahidol.ac.th.
Marut
M
Chantra
Division of Cardiology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Alisa
A
Limsuwan
Division of Endocrinology and Metabolism, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Pat
P
Mahachoklertwattana
D000293:Adolescent; D002303:Cardiac Output, Low / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D013902:Radiography, Thoracic; D013318:Stroke Volume / Q000502:physiology*; D013958:Thyroid Crisis / Q000150:complications* / Q000175:diagnosis
Graves’ disease; hyperthyroidism; pulmonary hypertension; pulmonary hypertensive crisis; thyroid storm