Rhodium-catalyzed P-P bond exchange reaction of diphosphine disulfides.
A rhodium-catalyzed exchange reaction of diphosphine disulfides, a diphosphine oxide, and a diphosphine is developed. Various symmetric diphosphine disulfides containing alkyl and phenyl groups are exchanged, giving equilibrium mixtures, from which unsymmetric diphosphine disulfides are readily separated by silica gel chromatography. The resulting unsymmetric diphosphine disulfide is regioselectively added to an aldehyde.
Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai, 980-8578, Japan. yama@m.tohoku.ac.jp arisawa@m.tohoku.ac.jp.
Mieko
M
Arisawa
Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai, 980-8578, Japan. yama@m.tohoku.ac.jp arisawa@m.tohoku.ac.jp.
Tomoki
T
Yamada
Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai, 980-8578, Japan. yama@m.tohoku.ac.jp arisawa@m.tohoku.ac.jp.
Saori
S
Tanii
Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai, 980-8578, Japan. yama@m.tohoku.ac.jp arisawa@m.tohoku.ac.jp.
Yuta
Y
Kawada
Department of Chemistry, Graduate School of Sciences, Tohoku University, Aoba, Sendai, 980-8578, Japan.
Hisako
H
Hashimoto
Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai, 980-8578, Japan. yama@m.tohoku.ac.jp arisawa@m.tohoku.ac.jp.
Masahiko
M
Yamaguchi