Renaut Corpuscles or Peripheral Nerve Infarcts? A Historical Overview.
Renaut corpuscles are cylindrical hyaline structures that arise from the peripheral nerve perineurium and project into the endoneurium. Despite their earlier accurate description in the French and German literature, Kernohan and Woltman (1938) reported very similar structures as "nerve infarcts" in a case series of vasculitic neuropathy. Krücke (1955) deserves credit for discovering this error and further explaining how peripheral nerves react differently (from brain parenchyma) to ischemia. We tried to elucidate the reason why Kernohan and Woltman, and others, made this scientific error by describing the historical evolution of our understanding of the structure and function of Renaut corpuscles.
Department of Neurology,Mayo Clinic,Rochester MN,55905,USA.
Mohamed
M
Kazamel
Department of Neurology,Mayo Clinic,Rochester MN,55905,USA.
Christopher J
CJ
Boes
D000818:Animals; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D010523:Peripheral Nervous System Diseases / Q000266:history / Q000473:pathology*
History of neuropathology; Joseph-Louis Renaut; Renaut bodies; Renaut corpuscles; Wilhelm Krücke