Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity.
OBJECTIVE
Histiocytic sarcoma (HS) is an extraordinary rare tumor and it has an offensive clinical course. HS of the uterine cervix is a far uncommon tumor with just a few cases described so far. Here we presented a case of primary HS of the uterine cervix in a 62-year-old female initially misdiagnosed as large cell non-keratinizing squamous cell carcinoma. To the best of our knowledge, this is the first reported case of HS of the uterine cervix from Iran.


METHODS
The patient presented with post-menopausal vaginal bleeding. Further evaluations revealed the presence of a relatively large cervical mass that was sampled. Under the preliminary diagnosis of large cell non-keratinizing squamous cell carcinoma, the patient underwent radical surgery. Postoperative pathological examination confirmed the diagnosis of HS of the uterine cervix. The patient received chemotherapy.


CONCLUSIONS
Clinical presentations of HS of the uterine cervix are very similar to more common cervical tumors; as a result its diagnosis relies on immunohistochemical methods. A correct diagnose could lead to the proper and timely treatment.
Fariba
F
Binesh
Mojgan
M
Karimi-Zarchi
Mohammad Reza
MR
Vahidfar
Zahra Kargar
ZK
Hadgiabadi
D000970:Antineoplastic Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D054747:Histiocytic Sarcoma / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007044:Hysterectomy; D008796:Metrorrhagia / Q000209:etiology; D008875:Middle Aged; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy
D000970:Antineoplastic Agents