Delayed diagnosis of bullous pyoderma gangrenosum with acute myelogenous leukemia.
Pyoderma gangrenosum (PG) is a rare, but serious neutrophilic dermatosis characterized by recurrent painful cutaneous ulcerations. It is commonly associated with inflammatory bowel disease, rheumatoid arthritis, and hematological malignancies. Because laboratory evaluations and histologic features of PG are nonspecific, diagnosis is based on the clinical features of the ulcer and requires exclusion of other conditions that cause such ulceration. The disease responds to glucocorticoids, immunosuppressives, and anti-inflammatory drugs. We present a 30-year-old man with acute myelogenous leukemia (subtype M5) and bullous PG. Treatment with high-dose prednisolone was successful.
Department of Dermatology, Inönü University, Malatya, Turkey.
S
S
Sener
Department of Dermatology, Malatya State Hospital, Malatya, Turkey.
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G
Sarac
Department of Dermatology, Malatya State Hospital, Malatya, Turkey.
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N
Altunisik
Department of Infectious Disease, School of Medicine, Inönü University, Malatya, Turkey.
Y
Y
Bayindir
D000328:Adult; D057210:Delayed Diagnosis; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology
D005938:Glucocorticoids; D011239:Prednisolone