Invasive Melanoma in a Patient with Congenital Ichthyosiform Erythroderma.
We describe the case of a 26-year-old woman with a history of congenital ichthyosiform erythroderma (CIE) who initially presented with a stage IIA amelanotic melanoma on her forearm that was surgically excised. We also review the literature on CIE-associated skin cancers and discuss the possible contribution of ichthyosis to the risk of cutaneous malignancies. Our findings emphasize the importance of close lifelong skin cancer screening in individuals with CIE and highlight the unique malignancy risk of these individuals.
Department of Dermatology, Stanford University Medical Center, Stanford, California.
Prajakta
P
Jaju
Department of Dermatology, Stanford University Medical Center, Stanford, California.
Roberto A
RA
Novoa
Department of Dermatology, Stanford University Medical Center, Stanford, California.|Dermatology Service, Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
Susan M
SM
Swetter
Department of Dermatology, Stanford University Medical Center, Stanford, California.
Kavita Y
KY
Sarin
D000328:Adult; D005260:Female; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000150:complications*; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery