Designing Micro- and Nanoswimmers for Specific Applications.
Self-propelled colloids have emerged as a new class of active matter over the past decade. These are micrometer sized colloidal objects that transduce free energy from their surroundings and convert it to directed motion. The self-propelled colloids are in many ways, the synthetic analogues of biological self-propelled units such as algae or bacteria. Although they are propelled by very different mechanisms, biological swimmers are typically powered by flagellar motion and synthetic swimmers are driven by local chemical reactions, they share a number of common features with respect to swimming behavior. They exhibit run-and-tumble like behavior, are responsive to environmental stimuli, and can even chemically interact with nearby swimmers. An understanding of self-propelled colloids could help us in understanding the complex behaviors that emerge in populations of natural microswimmers. Self-propelled colloids also offer some advantages over natural microswimmers, since the surface properties, propulsion mechanisms, and particle geometry can all be easily modified to meet specific needs. From a more practical perspective, a number of applications, ranging from environmental remediation to targeted drug delivery, have been envisioned for these systems. These applications rely on the basic functionalities of self-propelled colloids: directional motion, sensing of the local environment, and the ability to respond to external signals. Owing to the vastly different nature of each of these applications, it becomes necessary to optimize the design choices in these colloids. There has been a significant effort to develop a range of synthetic self-propelled colloids to meet the specific conditions required for different processes. Tubular self-propelled colloids, for example, are ideal for decontamination processes, owing to their bubble propulsion mechanism, which enhances mixing in systems, but are incompatible with biological systems due to the toxic propulsion fuel and the generation of oxygen bubbles. Spherical swimmers serve as model systems to understand the fundamental aspects of the propulsion mechanism, collective behavior, response to external stimuli, etc. They are also typically the choice of shape at the nanoscale due to their ease of fabrication. More recently biohybrid swimmers have also been developed which attempt to retain the advantages of synthetic colloids while deriving their propulsion from biological swimmers such as sperm and bacteria, offering the means for biocompatible swimming. In this Account, we will summarize our effort and those of other groups, in the design and development of self-propelled colloids of different structural properties and powered by different propulsion mechanisms. We will also briefly address the applications that have been proposed and, to some extent, demonstrated for these swimmer designs.
Institute for Bioengineering of Catalonia (IBEC) , Baldiri i Reixac 10-12, 08028 Barcelona, Spain.|Max-Planck-Institut für Intelligente Systeme , Heisenbergstr. 3, D-70569 Stuttgart, Germany.
Jaideep
J
Katuri
Max-Planck-Institut für Intelligente Systeme , Heisenbergstr. 3, D-70569 Stuttgart, Germany.|School of Materials Science and Engineering, Harbin Institute of Technology Shenzhen Graduate School , 518055 Shenzhen, China.
Xing
X
Ma
Max-Planck-Institut für Intelligente Systeme , Heisenbergstr. 3, D-70569 Stuttgart, Germany.
Morgan M
MM
Stanton
Institute for Bioengineering of Catalonia (IBEC) , Baldiri i Reixac 10-12, 08028 Barcelona, Spain.|Max-Planck-Institut für Intelligente Systeme , Heisenbergstr. 3, D-70569 Stuttgart, Germany.|Institució Catalana de Recerca i Estudis Avancats (ICREA) , Pg. Lluís Companys 23, 08010 Barcelona, Spain.
Samuel
S
Sánchez
D018407:Bacterial Physiological Phenomena; D003102:Colloids; D006801:Humans; D008297:Male; D049329:Nanostructures; D013094:Spermatozoa / Q000502:physiology
D003102:Colloids