New Validated Signal-averaging-based Electrocardiography Method to Determine His-ventricle Interval.
OBJECTIVE
The signal-averaging (SA) technique is used to record high-resolution electrocardiograms (HRECGs) showing cardiac micropotentials. We aimed to develop a non-invasive signal-averaging-based portable bedside device to determine His-ventricle interval.


METHODS
After amplifying the HRECG recordings, signal duration and voltage can be measured up to four decimal precision. To validate our system, comparison of the invasively and non-invasively determined HV intervals has been performed in 20 patients.


RESULTS
Our workgroup has developed a system capable of displaying and measuring cardiac micropotentials on storable ECG. Neither related paired-sample T-test (p=0.263) nor Wilcoxon's non-parametric signed ranks test (p=0.245) showed significant deviations of the HV intervals. Furthermore, related paired-sample T-test showed strong correlation (corr=0.910, p<0.001) between HV intervals determined by electrophysiology (EP) and non-invasive measurements.


CONCLUSIONS
Our research group managed to assemble and validate an easy to use device capable of determining HV intervals even under ambulatory conditions.
Department of Public Health Medicine, Medical School, University of Pécs, Pécs, Hungary balazs.nemeth@aok.pte.hu.|Zsigmondy Vilmos SPA Hospital, Harkány, Hungary.
Balázs
B
Németh
Hungarian Academy of Sciences, Budapest, Hungary.
Lóránd
L
Kellényi
Department of Obstetrics and Gynecology, Kaposi Mór Teaching Hospital, Kaposvár, Hungary.
István
I
Péterfi
Heart Institute, Medical School, University of Pécs, Pécs, Hungary.
Tamás
T
Simor
Heart Institute, Medical School, University of Pécs, Pécs, Hungary.
Diána
D
Ruzsa
Heart Institute, Medical School, University of Pécs, Pécs, Hungary.
Holczer
H
Lőrinc
Department of Public Health Medicine, Medical School, University of Pécs, Pécs, Hungary.
István
I
Kiss
Zsigmondy Vilmos SPA Hospital, Harkány, Hungary.
Iván
I
Péter
Zsigmondy Vilmos SPA Hospital, Harkány, Hungary.|Heart Institute, Medical School, University of Pécs, Pécs, Hungary.
Zénó
Z
Ajtay
D000328:Adult; D002036:Bundle of His / Q000502:physiology*; D054849:Cardiac Electrophysiology; D002320:Cardiovascular Physiological Phenomena; D004562:Electrocardiography / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013614:Tachycardia, Paroxysmal / Q000175:diagnosis / Q000503:physiopathology; D013615:Tachycardia, Sinoatrial Nodal Reentry / Q000175:diagnosis / Q000503:physiopathology; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000503:physiopathology
Cardiac electrophysiology; high-resolution electrocardiography; risk stratification