Use of MultiColor imaging in the assessment of suspected papilledema in 20 consecutive children.
To investigate the use of MultiColor Scanning Laser Imaging as an adjunct to traditional imaging modalities in the assessment of children with suspected disk swelling.



In this study of 20 consecutive children with suspected papilledema, MultiColor imaging was performed on all patients in addition to fundus examination, fundus autofluorescence, disk spectral domain optical coherence tomography (SD-OCT), and disk retinal nerve fiber layer thickness (RNFL) measurement. Diagnoses were determined in all 20 patients, and all images were evaluated by a medical retina specialist.



Of the 20 cases (average age 11 years [range, 5-16 years]; 10 males), papilledema was confirmed in 11 (55%) and pseudopapilledema diagnosed in 9 (45%). Of pseudopapilledema cases, there were 4 cases of optic disk drusen, 2 hypermetropic disks, 2 "crowded disks," and 1 anomalous disk. In patients with true papilledema, on the combined MultiColor image, a green shift in the form of an elevated green ring was seen consistently. This ring was also hyperreflective on the blue and green images and surrounded a central "shadow," which was seen best on near infrared reflectance (NIR). The disk margins and vasculature were obscured on the combined, green, blue, and NIR images. These changes were not present in the pseudopapilledema cases.



MultiColor imaging of disks with papilledema shows characteristic changes that may prove useful in differentiating true papilledema from pseudopapilledema. It is therefore a useful adjunct to traditional disk imaging modalities in assessing children with suspected disk swelling.
Queen Alexandra Hospital, Portsmouth, United Kingdom. Electronic address: andrew.malem@cantab.net.
Andrew
A
Malem
University Hospital Southampton NHS Foundation Trust, United Kingdom.
Gabriella
G
De Salvo
University Hospital Southampton NHS Foundation Trust, United Kingdom.
Stephanie
S
West
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009412:Nerve Fibers; D009898:Optic Disk; D015594:Optic Disk Drusen; D010211:Papilledema / Q000000981:diagnostic imaging*; D012165:Retinal Ganglion Cells; D041623:Tomography, Optical Coherence