Regression of hepatocellular carcinoma after treatment with Sofosbuvir - A case report.
Spontaneous regression (SR) of hepatocellular carcinoma (HCC) is a rare event. Several factors have been suggested as the underlying mechanism but the exact pathogenesis is not understood. The role of sofosbuvir in HCC regression has not been established yet. We report here a case of a 59 years old male who developed HCC secondary to chronic HCV infection. He failed treatment with interferon but the tumour regressed completely after treatment of hepatitis C with sofosbuvir and ribavirin for 48 weeks.
Final Year Medical Students, Rawalpindi Medical College, Rawalpindi.
Shafaq
S
Mahmood
Final Year Medical Students, Rawalpindi Medical College, Rawalpindi.
Aleesha
A
Gul
Final Year Medical Students, Rawalpindi Medical College, Rawalpindi.
Tayyaba
T
Saif
D000998:Antiviral Agents / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005838:Genotype; D016174:Hepacivirus; D019698:Hepatitis C, Chronic; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012254:Ribavirin; D000069474:Sofosbuvir / Q000627:therapeutic use*; D016896:Treatment Outcome
D000998:Antiviral Agents; D012254:Ribavirin; D000069474:Sofosbuvir
Hepatocellular carcinoma, Spontaneous neoplasm regression, Hepatitis C, Sofosbuvir.