Serial investigation of continuous glucose monitoring in a very low birth weight infant with transient late-onset hyperglycemia.
Transient late-onset hyperglycemia was detected in a very low birth weight (VLBW) infant (gestational age 28 weeks, birth weight 1,082 g) by routine point-of-care glucose monitoring.　The infant had no clinical symptom.　Serial continuous glucose monitoring (CGM) was conducted for 3 days at 31, 35, and 39 weeks' post conceptual age.　The difference values between the maximum and minimum blood glucose levels during the interval from one enteral feeding to the next enteral feeding were 32.3±14.3 mg/dL, 47.5±22.9 mg/dL, and 27.5±12.9 mg/dL for the 1st, 2nd, and 3rdCGM, respectively.　The serial change in the values was statistically significant (p<0.01).CGM is widely used as a routine clinical practice, which is true even in VLBW infants.　Hyperglycemic events detected by only once of CGM in otherwise healthy preterm infants have already been reported on larger numbers of patients.　To our knowledge, this is the first report that the change of glucose intolerance in a VLBW infant with transient late-onset hyperglycemia was investigated by serial CGM.
Department of Neonatal Medicine, Japanese Red Cross Musashino Hospital.
Toshihiko
T
Nakamura
Daisuke
D
Hatanaka
Mari
M
Nakamura
Michiko
M
Kusakari
Hidehiro
H
Takahashi
Takashi
T
Kamohara
D017668:Age of Onset; D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000097:blood*; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000097:blood*
D001786:Blood Glucose