A two-center comparative study of plastic and lumen-apposing large diameter self-expandable metallic stents in endoscopic ultrasound-guided drainage of pancreatic fluid collections.
OBJECTIVE
Endoscopic ultrasound-guided drainage of walled-off pancreatic fluid collections (PFCs) (pseudocyst [PC]; walled-off necrosis [WON]) utilizes double pigtail plastic stents (PS) and the newer large diameter fully covered self-expandable stents (FCSEMS) customized for PFC drainage. This study examined the impact of type of stent on clinical outcomes and costs.


METHODS
Retrospective two-center study. Outcome variables were technical and clinical success, need for repeat procedures, need for direct endoscopic necrosectomy (DEN), and procedure-related costs.


RESULTS
A total of 49 (PC: 31, WON: 18) patients were analyzed. Initially, PS was used in 37 and FCSEMS in 12. Repeat transmural drainage was required in 14 (PS: 13 [9 treated with PS, 4 treated with FCSEMS]; FCSEMS: 1 [treated with PS]) due to stent migration (PS: 3; FCSEMS: 1) or inadequate drainage (PS: 10). Technical success was 100%. Initial clinical success was 64.9% (25/38) for PSversus91.7% (11/12) for FCSEMS (P= 0.074). With repeat transmural stenting, final clinical success was achieved in 94.6% and 100%, respectively (P= 0.411). Compared to FCSEMS, PS was associated with greater need for repeat drainage (34.2%vs. 6.3%,P= 0.032). The need for and frequency of DEN was similar between both groups, but PS required more frequent balloon dilatation. PS was significantly cheaper for noninfected PC. Costs were similar for infected PC and WON.


CONCLUSIONS
PS was associated with a higher need for a second drainage procedure to achieve clinical success. The use of FCSEMS did not increase procedural costs for infected PC and WON.
Department of Gastroenterology and Hepatology, Changi General Hospital, Simei, Singapore.
Tiing Leong
TL
Ang
Department of Medicine, Faculty of Medicine, Gastrointestinal Endoscopy Excellent Center, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Pradermchai
P
Kongkam
Department of Gastroenterology and Hepatology, Changi General Hospital, Simei, Singapore.
Andrew Boon Eu
AB
Kwek
Department of Medicine, Faculty of Medicine, Gastrointestinal Endoscopy Excellent Center, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Piyachai
P
Orkoonsawat
Department of Medicine, Faculty of Medicine, Gastrointestinal Endoscopy Excellent Center, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Rungsun
R
Rerknimitr
Department of Gastroenterology and Hepatology, Changi General Hospital, Simei, Singapore.
Kwong Ming
KM
Fock
Endosonography; endotherapy; necrosectomy; pancreatic necrosis; pseudocyst