Systolic Blood Pressure on Admission and Mortality in Patients Hospitalized With Acute Heart Failure: Observations From the Gulf Acute Heart Failure Registry.
We investigated the role of systolic blood pressure (SBP) in relation to in-hospital and postdischarge mortality in patients admitted with acute heart failure (AHF). The SBP of 4848 patients aged ≥18 years admitted with AHF was categorized into 5 groups: ≤90, 91 to 119, 120 to 139, 140 to 161, and >161 mm Hg. After adjusting for several confounders, multivariate logistic regression models showed that admission SBP was a significant predictor of mortality among both patients with preserved left ventricular function (defined as left ventricular ejection fraction [LVEF] ≥40%) and patients with left ventricular dysfunction (LVEF <40%). The adjusted odds ratios of in-hospital, 3-month, and 1-year mortality in the lowest SBP groups were 7.06 (95% confidence interval [CI]: 3.28-15.20; P < .001), 2.59 (95% CI: 1.35-4.96; P = .004), and 3.10 (95% CI: 2.04-4.72; P < .001) times the odds in the highest admission group (SBP > 161 mm Hg), respectively. We conclude that low admission SBP is an independent predictor of mortality in patients with AHF. The higher the admission SBP, the better the prognosis, regardless of age or LVEF.
1 Directorate General of Primary Health Care, Ministry of Health, Muscat, Oman.
Jawad A
JA
Al-Lawati
2 Department of Cardiology, Royal Hospital, Muscat, Oman.|3 Director General of Specialized Medical Care, Ministry of Health, Muscat, Oman.
Kadhim J
KJ
Sulaiman
4 Department of Pharmacology and Clinical Pharmacy, College of Medicine and Health Sciences, Sultan Qaboos University and Gulf Health Research, Muscat, Oman.
Ibrahim
I
Al-Zakwani
5 Department of Medicine, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Alawi A
AA
Alsheikh-Ali
2 Department of Cardiology, Royal Hospital, Muscat, Oman.
Prashanth
P
Panduranga
6 Department of Cardiac Sciences, King Fahad Cardiac Centre, King Saud University, Riyadh, Saudi Arabia.
Khalid F
KF
Al-Habib
7 Department of Adult Cardiology, Hamad Medical Corporation and Qatar Cardiovascular Research Centre, Doha, Qatar.
Jassim
J
Al-Suwaidi
8 Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Wael
W
Al-Mahmeed
6 Department of Cardiac Sciences, King Fahad Cardiac Centre, King Saud University, Riyadh, Saudi Arabia.
Hussam
H
Al-Faleh
9 Department of Adult Cardiology, King Salman Heart Centre, King Fahad Medical City, Riyadh, Saudi Arabia.|10 Department of Cardiology, Tanta University, Tanta, Egypt.
Abdelfatah
A
El-Asfar
11 Department of Internal Medicine, Faculty of Medicine, Sana'a University, Sana'a, Yemen.
Ahmed
A
Al-Motarreb
12 Division of Cardiology, Al-Dabbous Cardiac Centre, Al Adan Hospital, Kuwait City, Kuwait.
Mustafa
M
Ridha
13 Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.
Bassam
B
Bulbanat
13 Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.
Mohammed
M
Al-Jarallah
14 Department of Cardiology, Dubai Hospital, Dubai, United Arab Emirates.
Nooshin
N
Bazargani
7 Department of Adult Cardiology, Hamad Medical Corporation and Qatar Cardiovascular Research Centre, Doha, Qatar.
Nidal
N
Asaad
15 Department of Cardiology, Mohammed Bin Khalifa Cardiac Centre, Al-Manamah, Bahrain.
Haitham
H
Amin
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000401:mortality*; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012042:Registries; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000401:mortality*
Arabs; Middle East; heart failure; mortality; systolic blood pressure