Examining the Proportion of Dietary Phosphorus From Plants, Animals, and Food Additives Excreted in Urine.
Phosphorus bioavailability is an emerging topic of interest in the field of renal nutrition that has important research and clinical implications. Estimates of phosphorus bioavailability, based on digestibility, indicate that bioavailability of phosphorus increases from plants to animals to food additives. In this commentary, we examined the proportion of dietary phosphorus from plants, animals, and food additives excreted in urine from four controlled-feeding studies conducted in healthy adults and patients with chronic kidney disease. As expected, a smaller proportion of phosphorus from plant foods was excreted in urine compared to animal foods. However, contrary to expectations, phosphorus from food additives appeared to be incompletely absorbed. The apparent discrepancy between digestibility of phosphorus additives and the proportion excreted in urine suggests a need for human balance studies to determine the bioavailability of different sources of phosphorus.
Center for Healthful Behavior Change, Department of Population Health, New York University School of Medicine, New York, New York. Electronic address: davidstjules@gmail.com.
David E
DE
St-Jules
Center for Healthful Behavior Change, Department of Population Health, New York University School of Medicine, New York, New York.
Ram
R
Jagannathan
Department of Suburban Dialysis, Davita, Inc., Denver, Colorado.
Lisa
L
Gutekunst
Division of Nephrology & Hypertension, University of California Irvine Medical Center, Orange, California.
Kamyar
K
Kalantar-Zadeh
Center for Healthful Behavior Change, Department of Population Health, New York University School of Medicine, New York, New York.
Mary Ann
MA
Sevick
D002611:Cheese / Q000032:analysis*; D004032:Diet; D005503:Food Additives / Q000008:administration & dosage; D006801:Humans; D008460:Meat / Q000032:analysis*; D016226:Phosphorus, Dietary / Q000493:pharmacokinetics / Q000652:urine*; D010945:Plants, Edible / Q000737:chemistry*; D051436:Renal Insufficiency, Chronic / Q000652:urine
D005503:Food Additives; D016226:Phosphorus, Dietary