Mitochondria-targeted fluorescent polymersomes for drug delivery to cancer cells.
Mitochondria is an attractive target to deliver anticancer drugs. We have synthesized a cationic triphenylphosphonium ion conjugated fluorescent polymer which self-assembles into nanosized polymersomes and targets the encapsulated anticancer drug doxorubicin to cancer cell mitochondria.
Department of Pharmaceutical Science, North Dakota State University, Fargo ND, USA.
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Kulkarni
Department of Pharmaceutical Science, North Dakota State University, Fargo ND, USA.
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Haldar
College of health professions, North Dakota State University, Fargo ND, USA.
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Confeld
College of health professions, North Dakota State University, Fargo ND, USA.
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CJ
Langaas
Department of Pharmaceutical Science, North Dakota State University, Fargo ND, USA.
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Yang
Department of Pharmaceutical Science, North Dakota State University, Fargo ND, USA.
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Qian
Department of Pharmaceutical Science, North Dakota State University, Fargo ND, USA.
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Mallik