Risk of statin therapy in elderly.
A meta-analysis of younger patients included in randomized trials found good evidence that statins reduce vascular events and mortality in people with high cholesterol and the risk of coronary heart disease. The use pf statin in the elderly prevents the disease but can exert considerable side effects.
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Ginter
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Kajaba
D000367:Age Factors; D000368:Aged; D002423:Cause of Death; D002784:Cholesterol / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood / Q000401:mortality; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy* / Q000401:mortality; D012016:Reference Values; D012307:Risk Factors; D014451:Ubiquinone / Q000097:blood; D018631:ras Proteins / Q000097:blood
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D014451:Ubiquinone; D002784:Cholesterol; D018631:ras Proteins