From Protein-RNA Predictions toward a Peptide-RNA Code.
The RNA field is undergoing a renaissance, with a deluge of proteins being identified to bind RNA. Two reports now introduce proteome-wide approaches that identify the peptides that are crosslinked to RNA (Castello et al., 2016; He et al., 2016).
Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Kristopher W
KW
Brannan
Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Molecular Engineering Laboratory, A(∗)STAR, Singapore. Electronic address: geneyeo@ucsd.edu.
Gene W
GW
Yeo
D000818:Animals; D001665:Binding Sites; D002843:Chromatin / Q000737:chemistry* / Q000378:metabolism / Q000528:radiation effects; D015870:Gene Expression; D006801:Humans; D051379:Mice; D000066450:Mouse Embryonic Stem Cells / Q000166:cytology / Q000378:metabolism* / Q000528:radiation effects; D009687:Nuclear Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D009690:Nucleic Acid Conformation; D010449:Peptide Mapping / Q000379:methods; D055668:Photochemical Processes; D011485:Protein Binding; D000072417:Protein Domains; D020543:Proteome / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D022661:RNA, Untranslated / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D014466:Ultraviolet Rays
D002843:Chromatin; D009687:Nuclear Proteins; D020543:Proteome; D022661:RNA, Untranslated; D016601:RNA-Binding Proteins