Profile of cognitive function in adults with duchenne muscular dystrophy.
BACKGROUND
Several studies have examined intellectual functioning of boys with duchenne muscular dystrophy (DMD). However, little is known about the remaining cognitive weaknesses in adults with DMD.


OBJECTIVE
The purpose of this study was to investigate the profile of cognitive functioning that is characteristics of adults with DMD.


METHODS
Twenty-four subscales from the Wechsler Adult Intelligence Scale III (WAIS-III), the Clinical Assessment for Attention (CAT), and the Wechsler Memory Scale Revised (WMS-R) were used to assess participants with DMD (N=15; mean age=30.4years).


RESULTS
Scores for Picture Completion, Arithmetic, Matrix Reasoning, Symbol Search, Letter-Number Sequencing, and Digit Span of the WAIS-III; all CAT scores, and Logical Memory and Delayed Logical Memory from the WMS-R were significantly deficient in adults with DMD in comparison to the normal population.


CONCLUSIONS
The ability to sequentially process auditory and visual information remains impaired in adults with DMD.
Okinawa International University, Ginowan, Ginowan-shi, Okinawa, Japan. Electronic address: y.ueda@okiu.ac.jp.
Yukihiko
Y
Ueda
National Hospital Organization Okinawa National Hospital, Ganeko, Ginowan-shi, Okinawa, Japan.
Shugo
S
Suwazono
Okinawa International University, Ginowan, Ginowan-shi, Okinawa, Japan.
Sino
S
Maedo
School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima-shi, Kagoshima, Japan.
Itsuro
I
Higuchi
D000328:Adult; D001288:Attention / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D005260:Female; D006801:Humans; D007360:Intelligence / Q000502:physiology*; D007361:Intelligence Tests; D008297:Male; D008568:Memory / Q000502:physiology*; D020388:Muscular Dystrophy, Duchenne / Q000503:physiopathology*; D014888:Wechsler Scales; D055815:Young Adult
Cognitive function; Duchenne muscular dystrophy; Neuropsychological profile; Sequential processing