Hepatic capsular rupture in pregnancy.
The syndrome of haemolysis, elevated liver enzymes and low platelets is a rare condition specific to pregnancy, affecting approximately 5-20% of all pre-eclamptic pregnancies. Described here is a woman in her first pregnancy, who experienced an intrauterine death following a significant hepatic haematoma and capsular rupture, in the absence of classical clinical features suggestive of pre-eclampsia. The events that followed suggested haemolysis, elevated liver enzymes and low platelets syndrome as the likely diagnosis. The patient's clinical course highlights the difficulties that may be encountered when making decisions about pregnant women with complicated medical and obstetric issues.
John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Charlotte J
CJ
Frise
John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Peyton
P
Davis
John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Graham
G
Barker
John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Douglas
D
Wilkinson
John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Lucy
L
Mackillop
Liver failure; acute; elevated liver enzymes and low platelets syndrome; haemolysis; pregnancy