Therapeutic evaluation of "Ayush Tulsi Jiwan Plus" oil for chronic musculoskeletal pain relief.
BACKGROUND
Chronic pain of musculoskeletal origin is a very common symptom and has major effect on the physical, mental, and economic aspects of the patients. There is always a crave among physicians and patients for effective analgesic, curable preparation that can be locally applied.


OBJECTIVE
The aim of this study is to assess the efficacy and safety of "Ayush Tulsi Jiwan Plus" oil in chronic pain management of musculoskeletal origin.


METHODS
Fifty patients of chronic musculoskeletal pain of unknown origin of mild to moderate condition were advised to apply "Ayush Tulsi Jiwan Plus" oil locally twice daily for 6 weeks and examined weekly. After completion of the treatment, the efficacy of the therapy was assessed on the basis of the subjective criteria such as perception of pain, tenderness, swelling, and joint mobility.


RESULTS
In this study, mean baseline score versus last visit score of pain (2.84 ± 0.68 vs. 1.33 ± 0.76), tenderness (1.64 ± 0.74 vs. 0.36 ± 0.56), and swelling (0.64 ± 0.85 vs. 0.38 ± 0.66) was significantly decreased, and also clinical improvement was seen in the study participants along with no evidence of adverse drug reactions.


CONCLUSIONS
The analysis of the overall effect of this "Ayush Tulsi Jiwan Plus" oil preparation was found efficacious and topically safe in chronic pain conditions. However, further study will be required with larger sample size and in heterogeneous population to elicit long-term effect of this polyherbal preparation.
Department of Pharmacology, IMS and SUM Hospital, SOA University, Bhubaneswar, Odisha, India.
Kunal
K
Sharma
Department of Orthopaedics, IMS and SUM Hospital, SOA University, Bhubaneswar, Odisha, India.
Jagannath
J
Sahoo
Central Research Institute of Ayurveda Drugs Development (Under CCRAS, New Delhi), Salt Lake, Kolkata, West Bengal, India.
Dipsundar
D
Sahu
Department of Samhita Sharir, Institute of Post Graduate Ayurveda Medical Educations and Research, Shyamadas Vaidya Shastra Pith Hospital, Kolkata, West Bengal, India.
Abichal
A
Chattopadhyay
Department of Pharmacology, IMS and SUM Hospital, SOA University, Bhubaneswar, Odisha, India.
Sanjay
S
Kumar
Department of Pharmacology, IMS and SUM Hospital, SOA University, Bhubaneswar, Odisha, India.
Sudhanshu Sekhar
SS
Mishra
Ayush Tulsi Jiwan Plus; chronic musculoskeletal pain; polyherbal oil