Mortality related to tuberculosis-HIV/AIDS co-infection in Brazil, 2000-2011: epidemiological patterns and time trends.
Co-infection of tuberculosis (TB)-HIV/AIDS is a persistent public health problem in Brazil. This study describes epidemiological patterns and time trends of mortality related to TB-HIV/AIDS co-infection. Based on mortality data from 2000-2011 (almost 12.5 million deaths), 19,815 deaths related to co-infection were analyzed. The average age-adjusted mortality rate was 0.97 deaths/100,000 inhabitants. The highest mortality rates were found among males, those in economically productive age groups, black race/color and residents of the South region. There was a significant reduction in the mortality coefficient at the national level (annual average percent change: -1.7%; 95%CI: -2.4; -1.0), with different patterns among regions: increases in the North, Northeast and Central regions, a reduction in the Southeast and a stabilization in the South. The strategic integration of TB-HIV/AIDS control programmes is fundamental to reduce the burden of mortality related to co-infection in Brazil.
Universidade Federal do Ceará, Fortaleza, Brasil.
Mauricélia da Silveira
MD
Lima
Universidade Federal do Ceará, Fortaleza, Brasil.|Instituto Federal de Educação, Ciência e Tecnologia do Ceará, Caucaia, Brasil.
Francisco Rogerlândio
FR
Martins-Melo
Universidade Federal do Ceará, Fortaleza, Brasil.|James Cook University, Townsville, Australia.
Jorg
J
Heukelbach
Universidade Federal do Ceará, Fortaleza, Brasil.
Carlos Henrique
CH
Alencar
Universidade Federal do Ceará, Fortaleza, Brasil.
Reagan Nzundu
RN
Boigny
Universidade Federal do Ceará, Fortaleza, Brasil.
Alberto Novaes
AN
Ramos
D000163:Acquired Immunodeficiency Syndrome / Q000401:mortality*; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D060085:Coinfection / Q000401:mortality*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D017678:Sex Distribution; D012959:Socioeconomic Factors; D062206:Spatial Analysis; D014376:Tuberculosis / Q000401:mortality*; D055815:Young Adult