Anti-N-methyl-D-aspartate receptor encephalitis and drug abuse - the probable role of molecular mimicry or the overstimulation of CB receptors in a 17-year-old adolescent - case report.
Anti-N-methyl-D-aspartate encephalitis is an autoimmune disorder characterized by autoantibodies produced against NMDA receptors. We report the case of a 17-year-old drug user teenager who presented with altered mental scale, psychiatric symptoms and autonomic dysfunction. In the background we diagnosed NMDA encephalitis. We supposed that synthetic cannabinoids/drugs may have lead to the of trigger NMDA encephalitis via the altered activation of the immune system and molecular mimicry mechanism.
Department of Pediatrics, University of Pécs, Hungary. tenyi.tamas@pte.hu.
Lidia
L
Hau
Gyorgyi
G
Csabi
Barnabas
B
Rozsai
Jozsef
J
Stankovics
Tamas
T
Tenyi
Katalin
K
Hollody
D000293:Adolescent; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D001323:Autoantibodies; D006801:Humans; D001523:Mental Disorders / Q000209:etiology; D018716:Molecular Mimicry; D016194:Receptors, N-Methyl-D-Aspartate; D019966:Substance-Related Disorders / Q000150:complications*
D001323:Autoantibodies; D016194:Receptors, N-Methyl-D-Aspartate