Association between obstructive sleep apnea and metabolic syndrome: a meta-analysis.
Evidence suggests that obstructive sleep apnea (OSA) is related to metabolic syndrome; however, the relationship among metabolic syndrome parameters (blood pressure, fasting blood glucose (FBG), high density lipoprotein (HDL) and low density lipoprotein (LDL)) and OSA is unclear.



PRISMA guidelines were followed for this study. Medline, Cochrane, EMBASE and Google Scholar databases were searched until December 23, 2015, using following terms: obstructive sleep apnea, sleep apnea, OSA and metabolic syndrome.



Ten studies were included in the analysis which included 2053 patients. Patients with OSA had higher systolic blood pressure (SBP) (pooled standard mean difference (SMD) = 0.56, 95% CI, 0.40 to 0.71, P.
. kongdelei@126.com.
De-Lei
DL
Kong
Zheng
Z
Qin
Wei
W
Wang
Ying
Y
Pan
Jian
J
Kang
Jian
J
Pang
D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D002318:Cardiovascular Diseases / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D012044:Regression Analysis; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications*; D013599:Systole; D016896:Treatment Outcome; D055815:Young Adult
D001786:Blood Glucose; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL