Sex differences in stroke: Review of current knowledge and evidence.
Stroke is a leading cause of death among women in the United States, and women are more affected by stroke than men. With women living longer than men, women experience not only a higher incidence of stroke but also more negative outcomes. Despite its lethal impact and high morbidity rate, the road from innovative bench research to improved clinical outcomes has been slow. This review explores the differential physiology, epidemiology, and clinical presentation of stroke between men and women, as well as the current status of laboratory and clinical data.
1 Texas A & M University College of Medicine, College Station, TX, USA.
Raghavendra L
RL
Girijala
1 Texas A & M University College of Medicine, College Station, TX, USA.
Farida
F
Sohrabji
2 Baylor College of Medicine, Houston, TX, USA.
Ruth L
RL
Bush
D000367:Age Factors; D000368:Aged; D000818:Animals; D002340:Carotid Artery Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D057510:Endovascular Procedures; D005260:Female; D054624:Health Status Disparities; D054625:Healthcare Disparities; D006801:Humans; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D012008:Recurrence; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
sex differences; stroke; women