Classic Kaposi's sarcoma - complete response to radiation therapy: a case report.
BACKGROUND
Classic Kaposi's sarcoma is a lymphatic endothelial cell neoplasm usually present on the skin of the upper and lower extremities. Although it commonly affects human immunodeficiency virus positive patients, there have been some human immunodeficiency virus negative cases reported. We report an uncommon presentation of stage IV classic Kaposi's sarcoma in an human immunodeficiency virus negative patient in Latin America with complete clinical response using only radiation therapy treatment.


METHODS
A 78-year-old Mexican man with no evidence of human immunodeficiency virus infection presented with a painful widespread dermatosis with maculopapular, nodular, violaceous lesions on his legs and ulcerated lesions on his feet. A biopsy confirmed the lesions as classic Kaposi's sarcoma. Radiotherapy treatment was delivered, prescribing a total dose of 30 Gy in 15 fractions with a complete clinical response within 15 months of follow-up.


CONCLUSIONS
This is an unusual case since it is uncommon to use radiation therapy as the single treatment in stage IV classic Kaposi's sarcoma; the efficacy of the treatment is shown in the impact in our patient's recurrence-free survival, local control, and palliation of our patient's symptoms.
Departments of Radiation Oncology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, 24096, Campeche, México. dr.kennet@hotmail.com.
Kennet
http://orcid.org/0000-0001-9506-6341
K
Ramírez
Departments of Radiation Oncology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, 24096, Campeche, México.
José
J
Zavala
Departments of Pathology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, 24096, Campeche, México.
David
D
Morán
Departments of Radiation Oncology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, 24096, Campeche, México.
Diana
D
Hernández
Departments of Radiation Oncology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, 24096, Campeche, México.
Alberto
A
Jiménez
D000368:Aged; D006801:Humans; D008297:Male; D011879:Radiotherapy Dosage; D012074:Remission Induction; D012514:Sarcoma, Kaposi / Q000473:pathology / Q000532:radiotherapy*; D012878:Skin Neoplasms / Q000473:pathology / Q000532:radiotherapy; D016896:Treatment Outcome
Case report; Classic Kaposi’s sarcoma; Kaposi’s sarcoma; Palliative radiotherapy in classic Kaposi’s sarcoma