Systemic inflammatory markers and sources of social support among older adults in the Memory Research Unit cohort.
Potential associations between systemic inflammation and social support received by a sample of 120 older adults were examined here. Inflammatory markers, cognitive function, social support and psychosocial wellbeing were evaluated. A structural equation modelling approach was used to analyse the data. The model was a good fitχ1082=256.13, p < 0.001; comparative fit index = 0.973; Tucker-Lewis Index = 0.962; root mean square error of approximation = 0.021; standardised root mean-square residual = 0.074). Chemokine levels were associated with increased age ( β = 0.276), receipt of less social support from friends ( β = -0.256) and body mass index ( β = -0.256). Results are discussed in relation to social signal transduction theory.
1 Trinity College, University of Dublin, Republic of Ireland.|2 Queen's University Belfast, UK.
Joanna
J
McHugh Power
1 Trinity College, University of Dublin, Republic of Ireland.
Sile
S
Carney
1 Trinity College, University of Dublin, Republic of Ireland.
Caoimhe
C
Hannigan
1 Trinity College, University of Dublin, Republic of Ireland.
Sabina
S
Brennan
1 Trinity College, University of Dublin, Republic of Ireland.
Hannah
H
Wolfe
1 Trinity College, University of Dublin, Republic of Ireland.
Marina
M
Lynch
2 Queen's University Belfast, UK.
Frank
F
Kee
1 Trinity College, University of Dublin, Republic of Ireland.
Brian
B
Lawlor
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000276:immunology*; D015992:Body Mass Index; D018925:Chemokines / Q000097:blood*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010549:Personal Satisfaction; D065840:Protective Factors; D012944:Social Support
D018925:Chemokines
age; health psychology; protective factors; quantitative methods