Real-time electronic adherence monitoring plus follow-up improves adherence compared with standard electronic adherence monitoring.
The impact of real-time electronic monitoring on antiretroviral therapy adherence warrants further study. We conducted an analysis of cohort participants that initially involved standard electronic adherence monitoring (EAM), followed by real-time EAM and home visits for sustained at least 48-h adherence interruptions. Immediately after switching between the two types of EAM, mean adherence among 112 participants increased from 84% to 93% and remained elevated for 6 months (P < 0.001). Real-time EAM is a promising approach for improving adherence.
aMassachusetts General Hospital Global Health and Harvard Medical School, Boston, Massachusetts, USA bMbarara University of Science and Technology, Mbarara, Uganda cEpicentre Mbarara Research Centre, Mbarara, Uganda dUniversity of California, San Francisco, California, USA.
Jessica E
JE
Haberer
Nicholas
N
Musinguzi
Alexander C
AC
Tsai
Yap
Y
Boum
Bosco M
BM
Bwana
Conrad
C
Muzoora
Peter W
PW
Hunt
Jeffrey N
JN
Martin
David R
DR
Bangsberg
D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D055118:Medication Adherence; D018670:Monitoring, Ambulatory / Q000379:methods*
D044966:Anti-Retroviral Agents