Metronidazole Induced Encephalopathy.
Metronidazole is an antimicrobial used for the treatment of anaerobic bacterial and protozoal infections. Neurological toxicity due to metronidazole use has been a matter of concern and many case reports of neurotoxicity are being published. We report here a case of a 32 years old male chronic alcoholic with multiple liver abscesses and history of 6 weeks use of metronidazole presenting with multiple episodes of seizures, burning sensation of feet and altered sensorium. MRI Brain revealed characteristic and reversible involvement of dentate nuclei and splenium of corpus callosum, typical of metronidazole induced encephalopathy (MIE).
Resident.
Nisarg
N
Thakkar
Resident.
Bhaarat
Resident.
Ramesh
R
Chand
Sr. Professor.
Raman
R
Sharma
Assistant Professor.
Sunil
S
Mahavar
Professor.
Swati
S
Srivastava
Junior Specialist, Department of Medicine, SMS Medical College, Jaipur, Rajasthan.
Arvind
A
Palawat
D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000009:adverse effects*; D020258:Neurotoxicity Syndromes / Q000209:etiology*
D000890:Anti-Infective Agents; D008795:Metronidazole