Cancer of the Esophagus and Esophagogastric Junction: An Eighth Edition Staging Primer.
This primer for eighth edition staging of esophageal and esophagogastric epithelial cancers presents separate classifications for the clinical (cTNM), pathologic (pTNM), and postneoadjuvant pathologic (ypTNM) stage groups, which are no longer shared. For pTNM, pT1 has been subcategorized as pT1a and pT1b for the subgrouping pStage I adenocarcinoma and squamous cell carcinoma. A new, simplified esophagus-specific regional lymph node map has been introduced. Undifferentiated histologic grade (G4) has been eliminated; additional analysis is required to expose histopathologic cell type. Location has been removed as a category for pT2N0M0 squamous cell cancer. The definition of the esophagogastric junction has been revised. ypTNM stage groups are identical for both histopathologic cell types, unlike those for cTNM and pTNM.
Cleveland Clinic, Cleveland, Ohio. Electronic address: ricet@ccf.org.
Thomas W
TW
Rice
University of Miami, Miami, Florida.
Hemant
H
Ishwaran
The University of Chicago, Chicago, Illinois.
Mark K
MK
Ferguson
Cleveland Clinic, Cleveland, Ohio.
Eugene H
EH
Blackstone
National Heart and Lung Institute, Imperial College, London, United Kingdom.
Peter
P
Goldstraw
D000230:Adenocarcinoma / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D004943:Esophagogastric Junction / Q000473:pathology*; D006801:Humans; D060787:Neoplasm Grading; D009367:Neoplasm Staging / Q000592:standards*; D011379:Prognosis
AJCC/UICC eighth edition staging; Esophageal cancer; Esophagogastric cancer; Staging