Cost Analysis of Ceramic Heads in Primary Total Hip Arthroplasty.
BACKGROUND
The advent of adverse local tissue reactions seen in metal-on-metal bearings, and the recent recognition of trunnionosis, have led many surgeons to recommend ceramic-on-polyethylene articulations for primary total hip arthroplasty. However, to our knowledge, there has been little research that has considered whether the increased cost of ceramic provides enough benefit over cobalt-chromium to justify its use. The primary purpose of this study was to compare the cost-effectiveness of ceramic-on-polyethylene implants and metal-on-polyethylene implants in patients undergoing total hip arthroplasty.


METHODS
Markov decision modeling was used to determine the ceramic-on-polyethylene implant revision rate necessary to be cost-effective compared with the revision rate of metal-on-polyethylene implants across a range of patient ages and implant costs. A different set of Markov models was used to estimate the national cost burden of choosing ceramic-on-polyethylene implants over metal-on-polyethylene implants for primary total hip arthroplasties. The Premier Research Database was used to identify 20,398 patients who in 2012 were ≥45 years of age and underwent a total hip arthroplasty with either a ceramic-on-polyethylene implant or a metal-on-polyethylene implant.


RESULTS
The cost-effectiveness of ceramic heads is highly dependent on the cost differential between ceramic and metal femoral heads and the age of the patient. At a cost differential of $325, ceramic-on-polyethylene bearings are cost-effective for patients <85 years of age. At a cost differential of $600, it is cost-effective to utilize ceramic-on-polyethylene bearings in patients <65 years of age, and, at a differential of $1,003, ceramic-on-polyethylene bearings are not cost-effective at any age.


CONCLUSIONS
The ability to recoup the initial increased expenditure of ceramic heads through a diminished lifetime revision cost is dependent on the price premium for ceramic and the age of the patient. A wholesale switch to ceramic bearings regardless of age or cost differential may result in an economic burden to the health system.


METHODS
Economic and decision analysis, Level III. See Instructions for Authors for a complete description of levels of evidence.
College of Health and Human Services (K.J.C.) and Belk College of Business (J.L.T.), University of North Carolina at Charlotte, Charlotte, North Carolina kjcarnes@uncc.edu.
Keith J
KJ
Carnes
OrthoCarolina Research Institute, Charlotte, North Carolina susan.odum@orthocarolina.com.
Susan M
SM
Odum
College of Health and Human Services (K.J.C.) and Belk College of Business (J.L.T.), University of North Carolina at Charlotte, Charlotte, North Carolina jtroyer@uncc.edu.
Jennifer L
JL
Troyer
OrthoCarolina Hip and Knee Center, Charlotte, North Carolina thomas.fehring@orthocarolina.com.
Thomas K
TK
Fehring
D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000191:economics*; D002516:Ceramics / Q000191:economics*; D003365:Costs and Cost Analysis; D005260:Female; D005270:Femur Head / Q000601:surgery; D006622:Hip Prosthesis / Q000191:economics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000191:economics / Q000601:surgery*; D011474:Prosthesis Design / Q000191:economics*; D011475:Prosthesis Failure; D012086:Reoperation