Pyrrolic molecular rotors acting as viscosity sensors with high fluorescence contrast.
New pyrrolic viscosity sensors exhibit one order of magnitude higher fluorescence contrast compared to that of the conventional phenolic analogues due to the viscosity-sensitive rotation of the asymmetric pyrrole group and successfully demonstrate mapping of intracellular viscosity by fluorescence lifetime imaging microscopy.
Department of Molecular Science and Technology, Ajou University, Suwon 443-749, Korea. opilkwon@ajou.ac.kr.
Seung-Chul
SC
Lee
Center for Theragnosis, Korea Institute of Science and Technology (KIST), 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791, Korea. sehoonkim@kist.re.kr.
Jeongyun
J
Heo
Department of Molecular Science and Technology, Ajou University, Suwon 443-749, Korea. opilkwon@ajou.ac.kr.
Jong-Wan
JW
Ryu
Advanced Photonics Research Institute (APRI), Gwangju Institute of Science and Technology (GIST), 123 Cheomdangwagi-ro, Buk-gu, Gwangju 61005, Korea. vsepr@gist.ac.kr.
Chang-Lyoul
CL
Lee
Center for Theragnosis, Korea Institute of Science and Technology (KIST), 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791, Korea. sehoonkim@kist.re.kr.
Sehoon
S
Kim
Department of Mechanical Engineering, Ajou University, Suwon, 443-749, Korea.
Joon-Sung
JS
Tae
Department of Mechanical Engineering, Ajou University, Suwon, 443-749, Korea.
Byung-Ohk
BO
Rhee
Department of Molecular Science and Technology, Ajou University, Suwon 443-749, Korea. opilkwon@ajou.ac.kr.
Sang-Wook
SW
Kim
Department of Molecular Science and Technology, Ajou University, Suwon 443-749, Korea. opilkwon@ajou.ac.kr.
O-Pil
OP
Kwon