Gorham disease: lymphangiomatosis with massive osteolysis.
Gorham disease (also referred to as vanishing bone disease or idiopathic massive osteolysis) is a rare skeletal condition that results in the localized replacement of bone with angiomas and fibrosis. The etiology and most effective treatment for this nonhereditary condition remain controversial in the medical literature. To our knowledge, we present the first case of post-traumatic Gorham disease that includes MR imaging (before and after radiation therapy), post-radiation CT with evidence of treatment effect (sclerosis), as well as asymptomatic bilateral renal lymphangiomata.
Georgetown University School of Medicine, 3900 Reservoir Road, NW, Washington, DC 20057. Electronic address: rmr92@georgetown.edu.
Ryan M
RM
Renacci
NewYork-Presbyterian Hospital/Weill Cornell Medical College, 525 E. 68th Street, New York, NY 10065. Electronic address: rob9074@med.cornell.edu.
Roger J
RJ
Bartolotta
D000328:Adult; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000000981:diagnostic imaging*; D008202:Lymphangioma / Q000150:complications* / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D010015:Osteolysis, Essential / Q000150:complications* / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed
Gorham disease; Lymphangiomatosis; MRI; Radiation; Vanishing bone disease