Recent Progress Toward the Synthesis of Trifluoromethyl- and Difluoromethyl-Substituted Cyclopropanes.
This Minireview describes recent advances toward the synthesis of trifluoromethyl- and difluoromethyl-substituted cyclopropanes. Synthetic methodologies using [2+1] cycloaddition, ring-contraction, and ring-closure cyclopropanations since 2010 are reported.
Normandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.
Maxence
M
Bos
Normandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.
Thomas
T
Poisson
Normandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.
Xavier
X
Pannecoucke
Centre in Green Chemistry and Catalysis, Faculty of Arts and Sciences, Department of Chemistry, Université de Montréal, PO Box 6128, Station Downtown, Montréal, Québec, H3C 3J7, Canada.
André B
AB
Charette
Normandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.
Philippe
P
Jubault
difluoromethyl; fluorine; substituted cyclopropanes; synthetic methods; trifluoromethyl