Mass spectrometry in life science research.
Investigating complex signatures of biomolecules by mass spectrometry approaches has become indispensable in molecular life science research. Nowadays, various mass spectrometry-based omics technologies are available to monitor qualitative and quantitative changes within hundreds or thousands of biological active components, including proteins/peptides, lipids and metabolites. These comprehensive investigations have the potential to decipher the pathophysiology of disease development at a molecular level and to monitor the individual response of pharmacological treatment or lifestyle intervention.
a Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center , Duesseldorf , Germany and.
Stefan
S
Lehr
b Institute for Clinical Diabetology, German Diabetes Center , Duesseldorf , Germany.
Daniel
D
Markgraf
D000818:Animals; D001690:Biological Science Disciplines; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D057170:Translational Research, Biomedical
2DE; Mass spectrometry; proteomics