Differentiation of subtypes of renal cell carcinoma: dynamic contrast-enhanced magnetic resonance imaging versus diffusion-weighted magnetic resonance imaging.
OBJECTIVE
The objective was to compare the performance of dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) magnetic resonance (MR) imaging in the differentiation of subtypes of renal cell carcinoma (RCC).


METHODS
This study included 45 renal tumors of clear cell (n=36) and non-clear-cell (n=9) RCC. The contrast enhancement ratios (CERs) and the apparent diffusion coefficient (ADC) values on MR imaging were compared between the clear cell and non-clear-cell RCC groups.


RESULTS
In the comparison of diagnostic performance between DCE and DW MR imaging, areas under the curves were 0.968 and 0.797 for the CERs of the corticomedullary and the ADC value.


CONCLUSIONS
The CER of the corticomedullary phase was more reliable in distinguishing between clear cell and non-clear-cell RCCs.
Department of Radiology, Kawasaki Medical School, Kurashiki, Japan. Electronic address: jiro@med.kawasaki-m.ac.jp.
Akira
A
Yamamoto
Department of Radiology, Kawasaki Medical School, Kurashiki, Japan.
Tsutomu
T
Tamada
Department of Radiology, Kawasaki Medical School, Kurashiki, Japan.
Katsuyoshi
K
Ito
Department of Radiology, Kawasaki Medical School, Kurashiki, Japan.
Teruki
T
Sone
Department of Radiology, Kawasaki Medical School, Kurashiki, Japan.
Akihiko
A
Kanki
Department of Radiology, Kawasaki Medical School, Kurashiki, Japan.
Daigo
D
Tanimoto
Department of Radiology, Kawasaki Medical School, Kurashiki, Japan.
Yasufumi
Y
Noda
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
D003287:Contrast Media
Contrast-enhanced imaging; Diffusion-weighted imaging; Renal cell carcinoma; Subtype