Adequacy of Using a Three-Item Questionnaire to Determine Zygosity in Chinese Young Twins.
The present study examined the adequacy of a three-item parent questionnaire in determining the zygosity of young Chinese twins and whether there was any association between parent response accuracy and some demographic variables. The sample consisted of 334 pairs of same-sex Chinese twins aged from 3 to 11 years. Three scoring methods, namely the summed score, logistic regression, and decision tree, were employed to evaluate parent response accuracy of twin zygosity based on single nucleotide polymorphism (SNP) information. The results showed that all three methods achieved high level of accuracy ranging from 91 to 93 % which was comparable to the accuracy rates in previous Chinese twin studies. Correlation results also showed that the higher the parents' education level or the family income was, the more likely parents were able to tell correctly that their twins are identical or fraternal. The present findings confirmed the validity of using a three-item parent questionnaire to determine twin zygosity in a Chinese school-aged twin sample.
Department of Psychology, The University of Hong Kong, Hong Kong SAR, China. shhoc@hku.hk.
Connie Suk-Han
0000-0001-5533-8621
CS
Ho
Department of Psychology, The University of Hong Kong, Hong Kong SAR, China.
Mo
M
Zheng
Department of Applied Social Sciences, City University of Hong Kong, Hong Kong SAR, China.
Bonnie Wing-Yin
BW
Chow
Department of Psychological Studies, The Education University of Hong Kong, Hong Kong SAR, China.
Simpson W L
SW
Wong
Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China.
Cadmon K P
CK
Lim
The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong SAR, China.
Mary M Y
MM
Waye
D000328:Adult; D044466:Asian People; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents; D020641:Polymorphism, Single Nucleotide; D015203:Reproducibility of Results; D012107:Research Design; D011795:Surveys and Questionnaires; D014427:Twins / Q000145:classification* / Q000235:genetics* / Q000523:psychology* / Q000706:statistics & numerical data; D014429:Twins, Dizygotic / Q000235:genetics / Q000523:psychology; D014430:Twins, Monozygotic / Q000235:genetics / Q000523:psychology
Chinese; Parent questionnaire; Young twins; Zygosity