Cancer treatment with nano-diamonds.
Diamond nano-particles find new and far-reaching applications in modern biomedical science and biotechnologies. Due to its excellent biocompatibility, nano-diamonds serve as versatile platforms that can be embedded within polymer-based microfilm devices. Nano-diamonds are complexed with a chemotherapeutic that enables sustained/slow release of the drug for a minimum of one month, with a significant amount of drug in reserve. This opens up the potential for highly localized drug release as a complementary and potent form of treatment with systemic injection towards the reduction of continuous dosing, and as such, attenuation of the often powerful side effects of chemotherapy. Nano-diamonds are quite economical, enabling the broad impact of these devices towards a spectrum of physiological disorders e.g. serving as a local chemotherapeutic patch, or as a pericardial device to suppress inflammation after open heart surgery. Nano-diamond patch could be used to treat a localized region where residual cancer cells might remain after a tumor is removed. Nano-diamonds can be used to explore a broad range of therapeutic classes, including additional small molecules, proteins, therapeutic antibodies, RNAi.
Amity Institute for Herbal Research and Studies, Block J-1, Room LG-13, Amity University UP, Sector-125, Noida-201313, India, charumicro@gmail.com.
Charu
C
Gupta
Amity Institute for Herbal Research and Studies, Amity University UP, Sector-125, Noida-201313, India.
Dhan
D
Prakash
Department of Zoology, R.G.P.G. College, Chippi Tank, Meerut-250001, India.
Sneh
S
Gupta
D000818:Animals; D006801:Humans; D058612:Nanodiamonds / Q000627:therapeutic use*; D009369:Neoplasms / Q000188:drug therapy*
D058612:Nanodiamonds