Hepatoid Adenocarcinoma of the Urachus.
Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis.
Department of Pathology, University of Washington, Seattle, WA, USA.
Daniel Fernando
0000-0003-1517-0240
DF
Gallego
Department of Surgery, Mercy Medical Center, Baltimore, MD, USA.
Carlos
0000-0002-6125-3170
C
Muñoz
Department of Pathology, Fundacion Valle del Lili, Cali, Colombia.
Carlos Andrés
CA
Jimenez
Department of Pathology, Universidad del Valle, Cali, Colombia.
Edwin
E
Carrascal