Familial Occurrence of Enteric Muco-Submucosal Elongated Polyp.
We report 2 cases of enteric muco-submucosal elongated polyps (EMSEPs) that presented with gastrointestinal bleeding. The 2 patients are siblings. They both had a history of percutaneous coronary intervention for coronary artery disease and were on dual antiplatelet therapy. They underwent endoscopic resection of the polyps, which displayed identical endoscopic and histological features compatible with EMSEP. This is the first report of familial occurrence of EMSEP, suggesting possible genetic involvement. It is also important to note that the use of antiplatelet agents appears to be a predisposing factor for gastrointestinal bleeding from EMSEP.
Division of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
Yuto
Y
Shimamura
Division of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
Kenji
K
Nakamura
Division of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
Takeshi
T
Okamoto
Division of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
Noriatsu
N
Imamura
Division of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
Naoki
N
Ishii
Division of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
Yoshiyuki
Y
Fujita