[Use of chemotherapy during pregnancy].
The presence of malignant tumors during pregnancy complicates the management of both tumor and pregnancy, since any diagnostic or therapeutic intervention could imply risks that may bring on detrimental effects to fetus or mother. The risks involved in exposing a fetus to cytotoxic therapy are associated to gestational age and the time of in utero exposure to that therapy. Cancer treatment has two different objectives: local control by surgery and radiotherapy, and one that seeks to eradicate systemic disease through chemotherapy, immunotherapy, hormone therapy, or targeted therapies.
Departamento de Ginecología y Obstetricia, Centro Médico ABC, Ciudad de México, México. dbh1714@gmail.com.
Denise N
DN
Benardete-Harari
Janisse
J
Kershenovich-Gersson
Diego
D
Meraz-Ávila
Javier Andrés
JA
Galnares-Olalde
Emilio José
EJ
Olaya-Guzmán
D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000075202:Contraindications; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*; D011295:Prenatal Care / Q000379:methods*; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced
D000970:Antineoplastic Agents
Cancer; Chemotherapy; Pregnancy; Teratogenesis