Discussion of 18F-FDG PET/CT imaging characteristics and diagnostic values of angioimmunoblastic T-cell lymphoma.
The aim of this study was to discuss18F-FDG PET/CT imaging characteristics and diagnostic values of angioimmunoblastic T-cell lymphoma (AITL). The PET/CT features of 24 cases of pathologically confirmed AITL were analyzed. The individual and total diagnostic values of 13 sites using computed tomography (CT) and positron emission tomography (PET)/CT were calculated. The maximum standard uptake value (SUVmax) of lesions with lymph node infiltration and extranodal organ infiltration were 5.4-25.1 (median, 9.7) and 1.5-12.5 (median, 5.5), respectively. The diagnostic sensitivity, specificity and accuracy of AITL using CT were 78.3%, 100%, and 87.8%, respectively; using PET/CT, these values were 98.9%, 100%, and 99.4%, respectively. One patient undergoing PET/CT staging was upstaged from stage II to III, and two patients were upstaged from stage III to IV. PET/CT is very valuable in the diagnosis and staging of AITL.
a Department of PET Center , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.
Dan
D
Shao
b Department of Radiology , Guangzhou First People's Hospital , Guangzhou , China.
Qiang
Q
Gao
c Department of Radiology , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.
Chang-Hong
CH
Liang
a Department of PET Center , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.
Shu-Xia
SX
Wang
D000328:Adult; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007119:Immunoblastic Lymphadenopathy / Q000000981:diagnostic imaging / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods; D049268:Positron-Emission Tomography; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D019788:Fluorodeoxyglucose F18
Immunoblastic lymphadenopathy; T cell; fluorodeoxyglucose F18; lymphoma; multidetector computed tomography; peripheral; positron emission tomography