". . . I've Gone Through This My Own Self, So I Practice What I Preach . . . ".
There has not been enough study of the processes by which site staff help participating community members and potential participants to understand complicated concepts for HIV vaccine trials. This article describes strategies reported in six focus group discussions with Community Advisory Board members, educators, and consent counselors at an active HIV vaccine trial site in South Africa. Thematic analysis identified a considerable range of strategies, and findings suggest that such staff do not only try to promote understanding of critical information but also try to build trust in communicated information, to respect cultural differences, and to promote voluntariness. Findings also suggest occasional tensions between these implicit goals. Actual engagement and consent encounters at HIV vaccine trial sites should be observed, recorded, and analyzed; and the relationship between practices and valued outcomes should be assessed. These efforts may help to make consent-related encounters as "potent" as possible given finite resources.
1 HIV AIDS Vaccines Ethics Group, University of KwaZulu-Natal, Pietermaritzburg South Africa.
Catherine
C
Slack
1 HIV AIDS Vaccines Ethics Group, University of KwaZulu-Natal, Pietermaritzburg South Africa.
Siya
S
Thabethe
1 HIV AIDS Vaccines Ethics Group, University of KwaZulu-Natal, Pietermaritzburg South Africa.
Graham
G
Lindegger
2 South African Research Ethics Training Initiative (SARETI), University of KwaZulu-Natal, Pietermaritzburg, South Africa.
Limba
L
Matandika
3 University of Toronto, Ontario, Canada.
Peter A
PA
Newman
1 HIV AIDS Vaccines Ethics Group, University of KwaZulu-Natal, Pietermaritzburg South Africa.
Philippa
P
Kerr
1 HIV AIDS Vaccines Ethics Group, University of KwaZulu-Natal, Pietermaritzburg South Africa.|2 South African Research Ethics Training Initiative (SARETI), University of KwaZulu-Natal, Pietermaritzburg, South Africa.
Doug
D
Wassenaar
4 University of Cape Town, South Africa.
Surita
S
Roux
4 University of Cape Town, South Africa.
Linda-Gail
LG
Bekker
D016915:AIDS Vaccines; D026683:Advisory Committees; D035843:Biomedical Research / Q000941:ethics*; D003142:Communication; D055812:Community-Based Participatory Research; D003159:Community-Institutional Relations; D032882:Comprehension; D003469:Culture; D032984:Ethics, Research; D017144:Focus Groups; D015658:HIV Infections; D006801:Humans; D007258:Informed Consent; D012108:Research Personnel; D035842:Research Subjects; D012111:Residence Characteristics; D013019:South Africa; D035502:Trust; D014838:Volunteers
D016915:AIDS Vaccines
clinical trials; communication in research; comprehension; ethics in HIV-prevention trials; informed consent; stakeholder engagement