An Update on Kaposi's Sarcoma: Epidemiology, Pathogenesis and Treatment.
Kaposi's sarcoma is an angioproliferative neoplasm which has undergone considerable epidemiologic change since the original description by Moritz Kaposi in the late 1800s. This opportunistic neoplasm gained widespread notoriety within the US during the height of the AIDS epidemic, where it was frequently found co-occurring with opportunistic infections. With the advent of modern antiretroviral therapies, as well as an increasing number of individuals on immunosuppression for autoimmune disease or organ transplantation, the landscape of the immunocompromised individual has changed. It is now important for clinicians to be mindful of Kaposi's sarcoma manifesting in a growing variety of clinical contexts.
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA.
Paul
P
Curtiss
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA.
Lauren C
LC
Strazzulla
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA. alvin.friedman-kien@nyumc.org.
Alvin E
AE
Friedman-Kien
Acquired immunodeficiency syndrome; Human immunodeficiency virus; Immunosuppression; Kaposi’s sarcoma