Combined Central and Peripheral Demyelination.
Demyelinating disorders are very common, but remains isolated to the part of nervous system they involve. However, infrequently, combined involvement of central and peripheral nervous system with demyelinating process have been described. We report one such rare case, with possible theories of common etiological basis. We present a middle aged male patient with Chronic Inflammatory Demyelinating Polyneuropathy(CIDP), who responded to immuno-modulation. Subsequently, he developed Acute Transverse Myelitis (ATM). Recently a common substrate protein, NF186 has been described as responsible for this rare clinical entity.
Asst. Prof.
Pranav B
PB
Joshi
Prof.
Sudhir V
SV
Shah
Asso. Prof.
Mayank A
MA
Patel
Senior Resident, Department of neurology, V.S. General Hospital, Ahmedabad, Gujarat.
Shailesh
S
Shailesh
D002493:Central Nervous System Diseases / Q000150:complications*; D003711:Demyelinating Diseases / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000150:complications*