Membrane binding, endocytic trafficking and intracellular fate of high-affinity antibodies to gangliosides GD1a and GM1.
Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC, UNC-CONICET), Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Fernando M
FM
Ruggiero
Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC, UNC-CONICET), Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Aldo A
AA
Vilcaes
Department of Neurology, Mishima Hospital, Niigata, Japan.
Nobuhiro
N
Yuki
Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC, UNC-CONICET), Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.. Electronic address: daniotti@dqb.fcq.unc.edu.ar.
José L
JL
Daniotti
D000089982:ADP-Ribosylation Factor 6; D020727:ADP-Ribosylation Factors / Q000235:genetics / Q000276:immunology; D000818:Animals; D000911:Antibodies, Monoclonal / Q000378:metabolism*; D000915:Antibody Affinity; D001324:Autoantigens / Q000276:immunology / Q000378:metabolism; D001692:Biological Transport; D016466:CHO Cells; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000276:immunology / Q000378:metabolism*; D003412:Cricetulus; D004705:Endocytosis / Q000276:immunology*; D011992:Endosomes / Q000276:immunology / Q000378:metabolism; D005677:G(M1) Ganglioside / Q000276:immunology / Q000378:metabolism*; D005732:Gangliosides / Q000276:immunology / Q000378:metabolism*; D015870:Gene Expression; D006801:Humans; D007700:Kinetics; D051379:Mice; D018345:Mice, Knockout; D057054:Molecular Imaging; D009474:Neurons / Q000166:cytology / Q000276:immunology / Q000378:metabolism; D011485:Protein Binding; D059008:Time-Lapse Imaging
D000089982:ADP-Ribosylation Factor 6; D000911:Antibodies, Monoclonal; D001324:Autoantigens; D005732:Gangliosides; C021298:ganglioside, GD1a; D005677:G(M1) Ganglioside; D020727:ADP-Ribosylation Factors
Anti-ganglioside antibody; Autoimmune neuropathy; Endocytosis; Ganglioside; Intracellular trafficking