A Correction Formula for the ST-Segment Measurements of AC-Coupled Electrocardiograms.
The ST segment of an electrocardiogram (ECG) is very important for the correct diagnosis of an acute myocardial infarction. Most clinical ECGs are recorded using an ACcoupled ECG amplifier. It is well known, that first-order high-pass filters used for the AC coupling can affect the ST segment of an ECG. This effect is stronger the higher the filter's cut-off frequency is and the larger the QRS integral is. We present a formula that estimates these changes in the ST segment and therefore allows for correcting ST measurements that are based on an ACcoupled ECG.



The presented correction formula can be applied when only four parameters are known: the possibly estimated QRS area A, the QRS duration W, the beat-to-beat interval TRR, and the filter time constant T, further, the time point Tjto correct-after the J point-must be specified.



The formula is correct within 0.6% until 40% ms after the J point and within 6% until 80 ms after the J point.



It is not necessary to have the raw data available and the formula therefore opens up the possibility of reevaluating studies that are based on ACcoupled ECGs and compare the results of such studies with studies that are based on newer, DC-coupled ECGs.
Ramun
R
Schmid
Jonas L
JL
Isaksen
Remo
R
Leber
Hans-Jakob
HJ
Schmid
Gianluca
G
Generali
Roger
R
Abacherli
D000465:Algorithms; D016477:Artifacts; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004562:Electrocardiography / Q000379:methods*; D006801:Humans; D015203:Reproducibility of Results; D000072657:ST Elevation Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted