Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge.
BACKGROUND
Dentine hypersensitivity is a common problem attributed by patent dentinal tubules. Ingredients incorporated in toothpastes aim to occlude patent dentinal tubules to minimize the dentine hypersensitivity. However, frequent consumption of acidic soft drinks may reverse the dentinal tubules' occlusion. In this in vitro study, the efficacy of dentinal tubules occluded by commercially available toothpastes to withstand different durations of an acidic soft drink challenge was investigated.


METHODS
One hundred and twenty dentine discs were divided into three groups. The discs from each group were brushed with toothpaste containing bioactive glass, arginine and control toothpaste. Each group was then divided into four subgroups and exposed to acidic soft drink over four different time durations.


RESULTS
The scoring and the percentage of occluded dentinal tubules by Novamin-containing toothpaste was significantly better compared with arginine or the control toothpaste. Acidic soft drink challenge reduced the extent of dentinal tubules occlusion along with time. Dentinal tubules occluded by Novamin-containing toothpaste withstand the acidic challenge comparatively for a longer period.


CONCLUSIONS
The findings demonstrated that occlusion of dentinal tubules is more efficient by the bioactive glass-containing toothpaste and thus may contribute to its better resistance to acidic soft drink challenge.
Department of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
M M
MM
Bakri
Department of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.|Department of Oral Physiology, School of Dentistry, Matsumoto Dental University, Shiojiri, Nagano, Japan.
M Z
MZ
Hossain
Department of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
F A
FA
Razak
Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
Z H
ZH
Saqina
Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
A A
AA
Misroni
Department of Community Oral Health and Clinical Prevention, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
N
N
Ab-Murat
Department of Oral Physiology, School of Dentistry, Matsumoto Dental University, Shiojiri, Nagano, Japan.
J
J
Kitagawa
Department of Community Oral Health and Clinical Prevention, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
R B
RB
Saub
D000143:Acids; D001120:Arginine / Q000494:pharmacology; D002253:Carbonated Beverages; D003804:Dentin; D057133:Dentin Desensitizing Agents / Q000494:pharmacology*; D003806:Dentin Permeability / Q000187:drug effects; D003807:Dentin Sensitivity / Q000188:drug therapy*; D005898:Glass; D006801:Humans; D008855:Microscopy, Electron, Scanning; D013997:Time Factors; D014070:Tooth / Q000187:drug effects / Q000648:ultrastructure*; D014100:Toothpastes / Q000494:pharmacology*
D000143:Acids; D057133:Dentin Desensitizing Agents; C510984:NovaMin; D014100:Toothpastes; D001120:Arginine
Acidic soft drink challenge; arginine-containing toothpaste; bioactive glass (Novamin)-containing toothpaste; dentinal tubule; dentine hypersensitivity