A Rare Case of Hepatitis C-Associated Cryoglobulinemic Duodenal Vasculitis.
Intestinal involvement of cryoglobulinemia is an uncommon manifestation and marker of severe vasculitis. We describe the case of a woman admitted to our service for management of acute renal failure and progressive gastrointestinal symptoms after initiating hepatitis C virus treatment with ribavirin and sofosbuvir 4 weeks prior. With an undetectable hepatitis C viral load and persistent symptoms despite hepatitis C virus therapy cessation, an upper endoscopy revealed duodenal sloughing, erythema, and bleeding, sparking suspicion for recurrence of cryoglobulinemic vasculitis.
Division of Gastroenterology, Department of Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Shivali
S
Berera
Department of Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Alexandra
A
Gomez
Department of Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Kevin
K
Dholaria
Division of Hepatology, Department of Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Leopoldo R
LR
Arosemena
Divison of Nephrology, Department of Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Marco A
MA
Ladino-Avellaneda
Department of Pathology, Department of Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Laura
L
Barisoni
Division of Hepatology, Department of Internal Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
Kalyan R
KR
Bhamidimarri