Loss of HCN channel mediated Ihcurrent following seizures accounts for movement dysfunction.
a Department of Physiology , University of Kentucky , Lexington , KY , USA.|b Epilepsy Center, University of Kentucky , Lexington , KY , USA.|c Department of Cell Biology and Anatomy , University of Calgary , Calgary , Alberta , Canada.|d Hotchkiss Brain Institute , Calgary , Alberta , Canada.
Jeffery A
JA
Boychuk
c Department of Cell Biology and Anatomy , University of Calgary , Calgary , Alberta , Canada.|d Hotchkiss Brain Institute , Calgary , Alberta , Canada.
G Campbell
0000-0002-8462-355X
GC
Teskey
D000818:Animals; D054815:Cyclic Nucleotide-Gated Cation Channels; D005552:Forelimb; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; D019579:Neocortex; D012377:Rodentia; D012640:Seizures
D054815:Cyclic Nucleotide-Gated Cation Channels; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Hyperpolarisation-activated; Ih current; cyclic nucleotide-gated (HCN) channels; forelimb behavior; intracortical microstimulation; motor cortex