Commandeering Channel Voltage Sensors for Secretion, Cell Turgor, and Volume Control.
Control of cell volume and osmolarity is central to cellular homeostasis in all eukaryotes. It lies at the heart of the century-old problem of how plants regulate turgor, mineral and water transport. Plants use strongly electrogenic H+-ATPases, and the substantial membrane voltages they foster, to drive solute accumulation and generate turgor pressure for cell expansion. Vesicle traffic adds membrane surface and contributes to wall remodelling as the cell grows. Although a balance between vesicle traffic and ion transport is essential for cell turgor and volume control, the mechanisms coordinating these processes have remained obscure. Recent discoveries have now uncovered interactions between conserved subsets of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that drive the final steps in secretory vesicle traffic and ion channels that mediate in inorganic solute uptake. These findings establish the core of molecular links, previously unanticipated, that coordinate cellular homeostasis and cell expansion.
Laboratory of Plant Physiology and Biophysics, Bower Building, University of Glasgow, Glasgow, G12 8QQ, UK.
Rucha
R
Karnik
Laboratory of Plant Physiology and Biophysics, Bower Building, University of Glasgow, Glasgow, G12 8QQ, UK.
Sakharam
S
Waghmare
Laboratory of Plant Physiology and Biophysics, Bower Building, University of Glasgow, Glasgow, G12 8QQ, UK.
Ben
B
Zhang
Laboratory of Plant Physiology and Biophysics, Bower Building, University of Glasgow, Glasgow, G12 8QQ, UK.
Emily
E
Larson
Laboratory of Plant Physiology and Biophysics, Bower Building, University of Glasgow, Glasgow, G12 8QQ, UK.
Cécile
C
Lefoulon
Centro de Bioinformatica y Simulacion Molecular, Universidad de Talca, Casilla 721, Talca, Chile.
Wendy
W
Gonzalez
Laboratory of Plant Physiology and Biophysics, Bower Building, University of Glasgow, Glasgow, G12 8QQ, UK. Electronic address: michael.blatt@glasgow.ac.uk.
Michael R
MR
Blatt
D001692:Biological Transport / Q000235:genetics / Q000502:physiology*; D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D015221:Potassium Channels / Q000235:genetics / Q000378:metabolism; D011485:Protein Binding; D050600:SNARE Proteins / Q000235:genetics / Q000378:metabolism
D010940:Plant Proteins; D015221:Potassium Channels; D050600:SNARE Proteins
K(+) channels; SNARE protein; Sec1-Munc18 protein; plant cell turgor; secretion; voltage-dependent; volume control