[Long-term results of severe acute pancreatitis management].
OBJECTIVE
To assess the long-term results and quality of life of patients after different medical and tactical approaches in treatment of severe acute pancreatitis.


METHODS
Long-term outcomes were studied in 210 patients with severe acute pancreatitis for the period 2003-2013. There were 144 (68.6%) men.


RESULTS
The quality of life of patients undergoing both aseptic (GIQLI - 112.9±1.3 points) and infected (GIQLI - 108.8±2.2 points) destructive complications of severe pancreatitis is lower (p=0.00001) compared with healthy population. Reccurence of acute pancreatitis was observed in 27.6% of patients. Diabetes mellitus developed in 40.5% and 23.6% of patients after infected and aseptic complications of severe pancreatitis respectively. Exocrine insufficiency was detected in 32.6% and 38.2% of patients who underwent aseptic and infected complications respectively. Postoperative hernia was observed in 30.8% of patients. Herewith, hernias (p<0.05) are predominantly formed after open operations (73,6%) than minimally invasive procedures (2.6%). Chronic pseudocyst was detected in 13.0% of patients after aseptic complications of severe pancreatitis and in 17.6% after infected complications.


CONCLUSIONS
Quality of life and long-term outcomes are better in patients who were treated using only conservative methods and/or minimally invasive surgical interventions.
Russian Medical Academy of Postgraduate Education; Sklifosovsky Research Institute of Emergency Care, Moscow, Russia.
A S
AS
Ermolov
Russian Medical Academy of Postgraduate Education.
D A
DA
Blagovestnov
Sklifosovsky Research Institute of Emergency Care, Moscow, Russia.
M L
ML
Rogal
Russian Medical Academy of Postgraduate Education.
D A
DA
Omel Yanovich
D000328:Adult; D000368:Aged; D000072700:Conservative Treatment / Q000379:methods / Q000706:statistics & numerical data; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000209:etiology; D019468:Disease Management; D010188:Exocrine Pancreatic Insufficiency / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D000069451:Long Term Adverse Effects / Q000453:epidemiology / Q000209:etiology / Q000523:psychology; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods / Q000706:statistics & numerical data; D010043:Outcome and Process Assessment, Health Care; D010192:Pancreatic Pseudocyst / Q000453:epidemiology / Q000209:etiology; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications / Q000453:epidemiology / Q000628:therapy; D011788:Quality of Life; D012008:Recurrence; D012426:Russia / Q000453:epidemiology