Platelet-derived Factor Concentrates with Hyaluronic Acid Scaffolds for Treatment of Deep Burn Wounds.
A deep burn wound is a critical condition that generally necessitates vascularized tissue coverage. We performed the injection of platelet-derived factor concentrates combined with non-cross-linked hyaluronic acid scaffolds for 2 patients with critical burn wounds with bone and tendon exposure and achieved successful healing. Hyaluronic acid was considered to have served as a controlled-release carrier of platelet-derived factors, being clinically effective for the treatment of deep burn wounds.
Department of Plastic Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; Department of Plastic Surgery, School of Medicine, University of Tokyo, Tokyo, Japan; Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan; and Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.
Takanobu
T
Mashiko
Department of Plastic Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; Department of Plastic Surgery, School of Medicine, University of Tokyo, Tokyo, Japan; Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan; and Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.
Toshiharu
T
Minabe
Department of Plastic Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; Department of Plastic Surgery, School of Medicine, University of Tokyo, Tokyo, Japan; Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan; and Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.
Tomomi
T
Yamakawa
Department of Plastic Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; Department of Plastic Surgery, School of Medicine, University of Tokyo, Tokyo, Japan; Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan; and Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.
Jun
J
Araki
Department of Plastic Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; Department of Plastic Surgery, School of Medicine, University of Tokyo, Tokyo, Japan; Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan; and Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.
Hitomi
H
Sano
Department of Plastic Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan; Department of Plastic Surgery, School of Medicine, University of Tokyo, Tokyo, Japan; Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan; and Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.
Kotaro
K
Yoshimura