A fluorescent probe for the selective detection of creatinine in aqueous buffer applicable to human blood serum.
A naphthalimide-based fluorescence light-up probe, FCP-Pd, has been designed and synthesized for selective detection and quantitation of creatinine in PBS buffer of pH 7.2 at 37 °C with a 'turn-on' response over a variety of interfering metal ions and/or anions and several biologically significant species. This probe is highly effective in estimating creatinine in human blood serum, which confirms the reliability and accuracy of this new system to be applied in clinical and toxicological analysis.
Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713104, West Bengal, India. pabitracc@yahoo.com.
Siddhartha
S
Pal
Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713104, West Bengal, India. pabitracc@yahoo.com.
Somenath
S
Lohar
Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713104, West Bengal, India. pabitracc@yahoo.com.
Manjira
M
Mukherjee
Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713104, West Bengal, India. pabitracc@yahoo.com.
Pabitra
P
Chattopadhyay
Department of Chemistry, SambhuNath College, Labpur, Birbhum 731303, West Bengal, India. dharachem@gmail.com.
Koushik
K
Dhara
D003404:Creatinine / Q000032:analysis* / Q000097:blood*; D005456:Fluorescent Dyes / Q000032:analysis* / Q000737:chemistry*; D006801:Humans; D053644:Naphthalimides / Q000032:analysis / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D005456:Fluorescent Dyes; D053644:Naphthalimides; D014867:Water; D003404:Creatinine