Anthelmintics: From discovery to resistance II (San Diego, 2016).
The second scientific meeting in the series: "Anthelmintics: From Discovery to Resistance" was held in San Diego in February, 2016. The focus topics of the meeting, related to anthelmintic discovery and resistance, were novel technologies, bioinformatics, commercial interests, anthelmintic modes of action and anthelmintic resistance. Basic scientific, human and veterinary interests were addressed in oral and poster presentations. The delegates were from universities and industries in the US, Europe, Australia and New Zealand. The papers were a great representation of the field, and included the use of C. elegans for lead discovery, mechanisms of anthelmintic resistance, nematode neuropeptides, proteases, B. thuringiensis crystal protein, nicotinic receptors, emodepside, benzimidazoles, P-glycoproteins, natural products, microfluidic techniques and bioinformatics approaches. The NIH also presented NIAID-specific parasite genomic priorities and initiatives. From these papers we introduce below selected papers with a focus on anthelmintic drug screening and development.
Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA. Electronic address: rjmartin@iastate.edu.
Richard J
RJ
Martin
Department of Infectious Diseases, University of Georgia, Athens, GA 30602, USA.
Adrian J
AJ
Wolstenholme
Center for Discovery and Innovation in Parasitic Diseases Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Conor R
CR
Caffrey
D000818:Animals; D000871:Anthelmintics / Q000302:isolation & purification* / Q000494:pharmacology*; D055808:Drug Discovery / Q000379:methods / Q000639:trends; D004351:Drug Resistance; D006373:Helminthiasis / Q000188:drug therapy*; D006801:Humans
D000871:Anthelmintics
Anthelmintics; Drug discovery; Resistance; San Diego; Scientific meeting