The ethanopharmacological aspect of carbon nanodots in turmeric smoke.
Smoke manifested ever since our ancient's lit fire; today it has evolved to become an environmental concern. However, medicinal smoke is still part of man's natural remedies, religious and cultural practices too. The Asiatic household practice of burning turmeric rhizomes to relieve nose and chest congestion is a well known yet never scientifically authenticated or studied practice. For the first time we investigate the components of these turmeric smudges, validate their antimicrobial and anticancer properties and their cell compatibility. With smoke there is always nanoparticulate carbon and turmeric smoke is no exception. If so, what is the role of the nano carbon (NC) in the turmeric smudge effect? This study isolated, characterized and exposed these secret natural NC undercover agents in turmeric smoke. Their unequivocal role in the ethanopharmocological activity of turmeric smudging has been demonstrated. This work opens a new avenue for use of such nano components of smoke for harnessing the ethanopharmacological property of various medicinal smokes, by excluding the smoke factor, through extracting the nano carbon material in them. This is a possibility to realizing the use of such naturally available nanomaterial, as an eco friendly substitute for the notorious anthropogenic nanomaterials.
Department of Bioresource and Food Science, Konkuk University, Seoul 143-701, Korea.
Sechul
S
Chun
Department of Bioresource and Food Science, Konkuk University, Seoul 143-701, Korea.
Manikandan
M
Muthu
Department of Bioresource and Food Science, Konkuk University, Seoul 143-701, Korea.
Enkhtaivan
E
Gansukh
DST Unit of Nanoscience (DST UNS), and Thematic Unit of Excellence (TUE), Department of Chemistry, Indian Institute of Technology Madras, Chennai - 600 036, India.
Pradeep
P
Thalappil
Department of Bioresource and Food Science, Konkuk University, Seoul 143-701, Korea.
Judy
J
Gopal
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002244:Carbon / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D030024:Curcuma / Q000737:chemistry*; D004285:Dogs; D005390:Fires; D006801:Humans; D061985:Madin Darby Canine Kidney Cells; D053758:Nanoparticles / Q000737:chemistry; D061848:Optical Imaging; D010946:Plants, Medicinal / Q000737:chemistry; D012906:Smoke / Q000032:analysis*
D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D012906:Smoke; D002244:Carbon