Three-Dimensional DNA Nanostructures Assembled from DNA Star Motifs.
Tile-based DNA self-assembly is a promising method in DNA nanotechnology and has produced a wide range of nanostructures by using a small set of unique DNA strands. DNA star motif, as one of DNA tiles, has been employed to assemble varieties of symmetric one-, two-, three-dimensional (1, 2, 3D) DNA nanostructures. Herein, we describe the design principles, assembly methods, and characterization methods of 3D DNA nanostructures assembled from the DNA star motifs.
Department of Chemistry, Purdue University, West Lafayette, IN, 47907, USA.
Cheng
C
Tian
School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. chuanzhang@sjtu.edu.cn.
Chuan
C
Zhang
D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods; D009690:Nucleic Acid Conformation; D059372:Nucleotide Motifs / Q000235:genetics*
D004247:DNA
Atomic force microscopy; Cryogenic electron microscopy; DNA nanostructure; Dynamic light scattering; Gel electrophoresis; Self-assembly; Single particle reconstruction; Star motif; Three-dimensional (3D)