Islet Cell Transplantation and Alternative Therapies.
Even though type 2 diabetes rates plateaued, type 1 diabetes continues to increase. Pancreas transplantation is a treatment modality for patients who suffer hypoglycemic unawareness or complications from diabetes. Islet cell transplantation success rates have improved with modification and advances in isolation, transplantation, and new immunosuppression regimens. The new cell sources as well as delivery ways are explored and being tested in human trials.
Endocrinology and Metabolism Institute, Cleveland Clinic, 9500 Euclid Avenue, F20, Cleveland, OH 44195, USA. Electronic address: hatipob@ccf.org.
Betul
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Hatipoglu
D002986:Clinical Trials as Topic; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D003924:Diabetes Mellitus, Type 2 / Q000601:surgery*; D006801:Humans; D016381:Islets of Langerhans Transplantation; D016035:Pancreas Transplantation
Beta cells; Islet transplantation; Pancreas transplantation; Type 1 diabetes