The use of serum beta-hydroxybutyrate to determine whether nursery pigs selected on the basis of clinical signs are anorexic.
The process of weaning pigs alters intestinal structures and influences piglet behavior, which can result in anorexia. When housed in large groups, affected pigs can be difficult to identify at an early stage. The clinical signs of anorexia include loss in body condition (thinness) and repetitive oral behavior (chomping). The objective of this study was to determine if pigs identified at 4 to 7 days post-weaning on the basis of clinical signs were anorexic based on elevated serum beta-hydroxybutyrate (BHB) levels (ketosis). A total of 240 pigs from 8 farms (30 pigs per farm) were selected based on observation of their abnormal oral behavior (Chomp;n= 10), poor body condition, (Thin;n= 10), or healthy appearance (Control;n= 10). Standard laboratory testing and a ketone handheld meter were used to measure BHB levels and were compared using non-parametric receiver operating characteristic analyses. Most pigs selected based on clinical signs were not anorexic as confirmed by their normal BHB levels.
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario (Perri, O'Sullivan, Friendship); Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan (Harding).
Amanda M
AM
Perri
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario (Perri, O'Sullivan, Friendship); Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan (Harding).
Terri L
TL
O'Sullivan
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario (Perri, O'Sullivan, Friendship); Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan (Harding).
John C S
JC
Harding
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario (Perri, O'Sullivan, Friendship); Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan (Harding).
Robert M
RM
Friendship
D020155:3-Hydroxybutyric Acid / Q000097:blood*; D000818:Animals; D000855:Anorexia / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D005260:Female; D008297:Male; D013552:Swine; D013553:Swine Diseases / Q000097:blood* / Q000175:diagnosis; D013851:Thinness / Q000097:blood / Q000662:veterinary
D020155:3-Hydroxybutyric Acid