Ovarian Fibroma: A Clinico-pathological Study of 23 Cases with Review of Literature.
The purpose of this study was to correlate the clinical findings, RMI-4 index and frozen section, in cases of ovarian fibroma with the final histopathology.



This is a retrospective study of clinical and pathological features of 23 patients of ovarian fibroma. The patient's age ranged from 34 to 66 years (mean-49 years). The most common presenting symptom was abdominal pain. On clinical examination, the mean size of ovarian tumor was 9.5 cm, CA-125 levels were found to be raised in 14 patients, and it was associated with ascites in 10 patients. USG showed a well-circumscribed mass (with a mean size of 14 cm), on the left side in 14 cases and on the right side in 9 patients. RMI-4 was calculated in all the patients, and it revealed the possibility of a benign histology in 17 patients. All patients underwent exploratory laparotomy with the removal of ovarian tumor followed by frozen section examination. All but one (22/23) patient had positive correlation among frozen section and final histopathological findings.



Ovarian fibroma generally tends to occur in post-menopausal women. All the patients in our study of ovarian fibroma were symptomatic, with the presence of palpable mass in majority of patients. RMI-4 Index correlated very well with benign nature of disease. Frozen section has an invaluable role at surgery; fertility-conserving surgery is the choice in young women.



Clinical findings, RMI-4 Index and frozen section, play vital roles before and during surgery in cases of benign ovarian tumors.
Department of Gynaecologic Oncology, Gujarat Cancer And Research Institute, Civil Hospital Lines, Asarwa, Ahmedabad, 380016 Gujarat India ; Flat A/1604, Shah Arcade-2, Rani Sati Marg, Near Western Express Highway, Malad East, Mumbai, 400097 Maharashtra India.
Nikhil Sadanand
0000-0003-1465-3582
NS
Parwate
Department of Gynaecologic Oncology, Gujarat Cancer And Research Institute, Civil Hospital Lines, Asarwa, Ahmedabad, 380016 Gujarat India.
Shilpa M
SM
Patel
Department of Gynaecologic Oncology, Gujarat Cancer And Research Institute, Civil Hospital Lines, Asarwa, Ahmedabad, 380016 Gujarat India.
Ruchi
R
Arora
Department of Gynaecologic Oncology, Gujarat Cancer And Research Institute, Civil Hospital Lines, Asarwa, Ahmedabad, 380016 Gujarat India.
Monisha
M
Gupta
Frozen section; Histopathological findings; Ovarian fibroma; RMI-4 index