A Radial Actin Network in Apical Constriction.
Contractile actomyosin networks are central to cell shape change, rearrangements, and migration during animal tissue morphogenesis. In this issue of Developmental Cell, Coravos and Martin (2016) report that the actin network is radially polarized in apically constricting cells, suggesting a constriction model similar to the contraction mechanism in muscle sarcomeres.
Institute for Developmental Biochemistry, Medical School, University of Göttingen, 37077 Göttingen, Germany.
Zhiyi
Z
Lv
Institute for Developmental Biochemistry, Medical School, University of Göttingen, 37077 Göttingen, Germany. Electronic address: joerg.grosshans@medizin.uni-goettingen.de.
Jörg
J
Großhans
D000199:Actins; D000205:Actomyosin; D000818:Animals; D016764:Cell Polarity; D003250:Constriction; D009024:Morphogenesis
D000199:Actins; D000205:Actomyosin