[Effect of autonomic denervation on the secretory function of submandibular glands].
Submandibular gland is innervated by sympathetic and parasympathetic nerves, both of which work synergistically to promote the salivation of the glands. However, denervation does not always produce an inhibitive effect. Regeneration secretion was put forward to describe the situation in which the glands after denervation were found to be supersensitive to the stimulation of several agonists of saliva secretion-related receptors. It is of clinical significance to get a good understanding of the secretory mechanism changes in the autonomically denervated submandibular gland. The present paper aims to review the studies on the denervation effects on the submandibular gland.
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
X M
XM
Zhang
Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
L L
LL
Wu
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
G Y
GY
Yu
Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Y
Y
Zhang
D017763:Autonomic Denervation; D003714:Denervation; D004558:Electric Stimulation; D010275:Parasympathetic Nervous System; D012463:Saliva; D012472:Salivation; D013363:Submandibular Gland