The 1stBaltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 2016. Summary and Consensus Statements: Group I - Peri-Implantitis Aetiology, Risk Factors and Pathogenesis.
BACKGROUND
The task of Group 1 was to review and update the existing data concerning aetiology, risk factors and pathogenesis of peri-implantitis. Previous history of periodontitis, poor oral hygiene, smoking and presence of general diseases have been considered among the aetiological risk factors for the onset of peri-implant pathologies, while late dental implant failures are commonly associated with peri-implantitis and/or with the application of incorrect biomechanical forces. Special interest was paid to the bone cells dynamics as part of the pathogenesis of peri-implantitis.


METHODS
The main areas indagated by this group were as follows: influence of smoking, history of periodontitis and general diseases on peri-implantitis development, bio-mechanics of implant loading and its influence on peri-implant bone and cellular dynamics related to the pathogenesis of peri-implantitis. The systematic reviews and/or meta-analyses were registered in PROSPERO, an international prospective register of systematic reviews: http://www.crd.york.ac.uk/PROSPERO/. The literature in the corresponding areas of interest was screened and reported following the PRISMA (Preferred Reporting Item for Systematic Review and Meta-Analysis) Statement: http://www.prisma-statement.org/. Method of preparation of the systematic reviews, based on comprehensive search strategies, was discussed and standardized. The summary of the materials and methods employed by the authors in preparing the systematic reviews and/or meta-analyses is presented in Preface chapter.


RESULTS
The results and conclusions of the review process are presented in the respective papers. One systematic review with meta-analysis, three systematic reviews and one theoretical analysis were performed. The group's general commentaries, consensus statements, clinical recommendations and implications for research are presented in this article.
Department of Medical, Surgical and Health Sciences, University of Trieste Italy.
Claudio
C
Stacchi
Private Practice, Trieste Italy.
Francesca
F
Andolsek
Department of Maxillofacial Surgery, Lithuanian University of Health Sciences, Kaunas Lithuania.
Inesa
I
Astramskaite
Department of Medical, Surgical and Health Sciences, University of Trieste Italy.
Federico
F
Berton
Department of Medical, Surgical and Health Sciences, University of Trieste Italy.
Roberto
R
Di Lenarda
Faculty of Dental Medicine, University of Porto (FMDUP), Porto Portugal.
Maria Helena
MH
Fernandes
Department of Medical, Surgical and Health Sciences, University of Trieste Italy.
Andrea
A
Frassetto
Faculty of Dental Medicine, University of Porto (FMDUP), Porto Portugal.
Pedro de Sousa
PS
Gomes
Department of Oral and Dental Pathology, Lithuanian University of Health Sciences, Kaunas Lithuania.
Zygimantas
Z
Guobis
Department of Oral and Maxillofacial Surgery and Oral Medicine Faculty of Odontology, Malmö University Sweden.
Ryo
R
Jimbo
Department of Maxillofacial Surgery, Lithuanian University of Health Sciences, Kaunas Lithuania.
Gintaras
G
Juodzbalys
Department of Medical, Surgical and Health Sciences, University of Trieste Italy.
Aiman
A
Khoury
Department of Maxillofacial Surgery, Lithuanian University of Health Sciences, Kaunas Lithuania.
Ricardas
R
Kubilius
Prosthetic Dentistry and Stomatognathic Physiology, Research Unit of Oral Health Sciences, Faculty of Medicine, University of Oulu, Medical Research Center Oulu, Oulu University Hospital and University of Oulu Finland.
Ritva
R
Kuoppala
Private Practice, Cassano allo Ionio Italy.
Teresa
T
Lombardi
Department of Prosthodontics, Lithuanian Universty of Health Sciences, Kaunas Lithuania.
Julius
J
Maminskas
Department of Oral and Dental Pathology, Lithuanian University of Health Sciences, Kaunas Lithuania.
Ingrida
I
Pacauskiene
Department of Medical, Surgical and Health Sciences, University of Trieste Italy.
Giuseppe
G
Perinetti
Department of Maxillofacial Surgery, Lithuanian University of Health Sciences, Kaunas Lithuania.
Lukas
L
Poskevicius
Department of Maxillofacial Surgery, Lithuanian University of Health Sciences, Kaunas Lithuania.
Mindaugas
M
Pranskunas
Vilnius Implantology Center, Vilnius Lithuania.
Algirdas
A
Puisys
Prosthetic Dentistry and Stomatognathic Physiology, Research Unit of Oral Health Sciences, Faculty of Medicine, University of Oulu, Medical Research Center Oulu, Oulu University Hospital and University of Oulu Finland.
Aune
A
Raustia