No Adverse Effects After Radioiodine Treatment at 3 Weeks of Pregnancy.
Radioactive iodine is used for the treatment of hyperthyroidism. Because it accumulates in the fetal thyroid, its administration during pregnancy may cause severe and potentially irreversible hypothyroidism in neonates, with consequent mental retardation, and it is contraindicated during the whole pregnancy. We present a case of a pregnant woman inadvertently treated with 1 mCi (37 MBq) of I in the earliest period of pregnancy and subsequently gave birth to a male infant without signs or symptoms of hypothyroidism or any other damage. This case illustrates that when radioactive iodine administration happens around the third week of gestation pregnancy outcome can be normal.
From the *Division of Clinical Pharmacology, Department of Medicine, University Hospital Centre Zagreb, Zagreb; †Department of Biotechnology, University of Rijeka, Rijeka; and ‡School of Medicine, University of Zagreb, Zagreb, Croatia.
Matea
M
Radacic-Aumiler
Iva
I
Kraljickovic
Viktorija
V
Edeljic-Turk
Ksenija
K
Makar-Ausperger
Robert
R
Likic
Iveta
I
Simic
D005260:Female; D005333:Fetus / Q000187:drug effects / Q000528:radiation effects; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000532:radiotherapy*; D007037:Hypothyroidism / Q000209:etiology*; D007223:Infant; D007231:Infant, Newborn; D007457:Iodine Radioisotopes / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000532:radiotherapy*; D019275:Radiopharmaceuticals / Q000009:adverse effects* / Q000627:therapeutic use; D055815:Young Adult
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals