Inflammatory biomarkers of coronary heart disease.
Coronary heart disease (CHD), characterized by inflammation and accumulation of plaques mainly comprised of lipids, calcium and inflammatory cells in the walls of coronary arteries. CHD is exacerbated by specific cardiovascular risk factors, such as obesity, diabetes mellitus, and hypertension. The current review focuses on the critical role of traditional inflammatory biomarkers, including interleukin-6, C-reactive protein (CRP), complement, CD40 and myeloperoxidase (MPO), in the pathogenesis of CHD.
Department of Cardiology, Baotou Central Hospital, Baotou, China.
Hongyu
H
Li
Department of Radiology,Baotou Central Hospital, Baotou, China.
Kai
K
Sun
Department of Cardiology, Baotou Central Hospital, Baotou, China, ruiping_zhao@yahoo. com.
Ruiping
R
Zhao
Department of Surgery, Baotou Central Hospital, Baotou, China.
Jiang
J
Hu
Department of Cardiology, Baotou Central Hospital, Baotou, China.
Zhiru
Z
Hao
Department of Cardiology, Baotou Central Hospital, Baotou, China.
Fei
F
Wang
Department of Cardiology, Baotou Central Hospital, Baotou, China.
Yaojun
Y
Lu
Department of Cardiology, Baotou Central Hospital, Baotou, China.
Fu
F
Liu
Department of Cardiology, Baotou Central Hospital, Baotou, China.
Yong
Y
Zhang
D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism; D019013:CD40 Antigens / Q000097:blood; D023201:CD40 Ligand / Q000097:blood; D003165:Complement System Proteins / Q000378:metabolism; D003324:Coronary Artery Disease / Q000097:blood / Q000209:etiology; D003327:Coronary Disease / Q000097:blood* / Q000209:etiology; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D008955:Models, Cardiovascular; D009195:Peroxidase / Q000097:blood; D019947:Receptors, Interleukin-6 / Q000097:blood; D000685:Serum Amyloid A Protein / Q000378:metabolism
D015415:Biomarkers; D019013:CD40 Antigens; C508603:IL6R protein, human; D018836:Inflammation Mediators; D019947:Receptors, Interleukin-6; D000685:Serum Amyloid A Protein; D023201:CD40 Ligand; D003165:Complement System Proteins; D002097:C-Reactive Protein; D009195:Peroxidase