Photoelectrochemical enzymatic biosensors.
Enzymatic biosensors have been valuable bioanalytical devices for analysis of diverse targets in disease diagnosis, biological and biomedical research, etc. Photoelectrochemical (PEC) bioanalysis is a recently emerged method that promptly becoming a subject of new research interests due to its attractive potential for future bioanalysis with high sensitivity and specificity. PEC enzymatic biosensors integrate the inherent sensitivities of PEC bioanalysis and the selectivity of enzymes and thus share their both advantages. Currently, PEC enzymatic biosensors have become a hot topic of significant research and the recent impetus has grown rapidly as demonstrated by increased research papers. Given the pace of advances in this area, this review will make a thorough discussion and survey on the fundamentals, sensing strategies, applications and the state of the art in PEC enzymatic biosensors, followed by future prospects based on our own opinions. We hope this work could provide an accessible introduction to PEC enzymatic biosensors for any scientist.
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation, Center of Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, Jiangsu, PR China. Electronic address: zww@nju.edu.cn.
Wei-Wei
WW
Zhao
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation, Center of Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, Jiangsu, PR China.
Jing-Juan
JJ
Xu
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation, Center of Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, Jiangsu, PR China.
Hong-Yuan
HY
Chen
D000818:Animals; D055162:Biocatalysis; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D006801:Humans; D008027:Light; D008958:Models, Molecular; D055668:Photochemical Processes
Bioanalysis; Biosensors; Enzyme; Photoelectrochemical; Review