Two New Pyripyropenes from the Marine Fungus Fusarium lateritium 2016F18-1.
Two new pyripyropenes, 13-dehydroxy-1,11-deacetylpyripyropene A (1) and 1-deacetylpyripyropene A (2), together with six known compounds, were isolated from a marine fungus Fusarium lateritium 2016F18-1 which was associated with the sponge Phyllospongia foliascens. Their structures were established mainly based on NMR and MS data. Their cytotoxic activities against human cancer cells CNE1, CNE2, HONE1, SUNE1, GLC82, and HL7702 were evaluated.
School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, P. R. China.
Qing-Xiang
QX
Cao
School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, P. R. China.
Jun-Hua
JH
Wei
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Cancer Center, Sun Yat-sen University, Guangzhou, 510060, P. R. China.
Rong
R
Deng
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Cancer Center, Sun Yat-sen University, Guangzhou, 510060, P. R. China.
Gong-Kan
GK
Feng
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Cancer Center, Sun Yat-sen University, Guangzhou, 510060, P. R. China.
Xiao-Feng
XF
Zhu
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, P. R. China.|Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou, 510006, P. R. China.
Wen-Jian
WJ
Lan
School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, P. R. China.
Hou-Jin
HJ
Li
D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D005670:Fusarium / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D011725:Pyridines / Q000737:chemistry* / Q000633:toxicity; D012717:Sesquiterpenes / Q000737:chemistry* / Q000633:toxicity
C000616674:1-deacetylpyripyropene A; C000616691:13-dehydroxy-1,11-deacetylpyripyropene A; D011725:Pyridines; D012717:Sesquiterpenes

Fusarium lateritium
; Cytotoxic activities; Marine fungus; Pyripyropene