Experimental Hepatocyte Transplantation in Pigs.
Technical issues of experimental hepatocyte transplantation in pigs, i.e., selection of animals, anesthesia, route of transplantation, and segment-specific transplantation have described.
Department of Organ Fabrication, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Eiji
E
Kobayashi
Division for Advanced Medical Sciences, National Center for Child Health and Development, 2-10-1 Ookura, Setagaya-ku, Tokyo, 157-8535, Japan. enosawa-s@ncchd.go.jp.
Shin
S
Enosawa
Department of Life Sciences, School of Agriculture, Meiji University, 1-1-1 Higashimita, Tama-ku, Kawasaki, 214-8571, Japan.
Hiroshi
H
Nagashima
D000818:Animals; D030801:Animals, Genetically Modified; D017690:Cell Transplantation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D005260:Female; D022781:Hepatocytes / Q000637:transplantation*; D008099:Liver / Q000033:anatomy & histology / Q000601:surgery*; D008297:Male; D023421:Models, Animal; D011169:Portal Vein / Q000601:surgery; D011182:Postoperative Care / Q000379:methods; D013552:Swine; D013556:Swine, Miniature / Q000502:physiology*; D020858:Tissue and Organ Harvesting / Q000295:instrumentation / Q000379:methods; D014471:Umbilical Veins / Q000601:surgery
Animal model; Intraportal injection; Pig; Segment-specific transplantation; Umbilical vein