Making better CRISPR libraries.
A new algorithm improves the performance of CRISPR-based genetic screens in mammals.
Biodynamic Optical Imaging Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.|Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, Peking University, Beijing, China.
Shiyou
S
Zhu
Biodynamic Optical Imaging Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.|Beijing Advanced Innovation Center for Genomics, Peking University, Beijing, China.|Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.
Wensheng
0000-0002-8053-2423
W
Wei
D000818:Animals; D064113:CRISPR-Cas Systems; D064112:Clustered Regularly Interspaced Short Palindromic Repeats; D015870:Gene Expression; D015723:Gene Library; D005820:Genetic Testing
CRISPR; chromosomes; computational biology; genes; genetic screening; human; nucleosomes; systems biology