Native Mitral Valve Endocarditis Caused byNeisseria elongatasubsp.nitroreducensin a Patient with Marfan Syndrome: First Case in Italy and Review of the Literature.
Neisseria elongata(NE) is an aerobic Gram-negative organism that constitutes part of the commensal human normal oropharyngeal flora. Although previously considered not to be pathogenic, it has been recognized as an occasional cause of significant infections in humans. We report here the first case in Italy of infective endocarditis of a native prolapsing mitral valve in a patient with Marfan syndrome, caused by NE subspeciesnitroreducenswhich has been rarely isolated from clinical specimens. The culprit organism has been confirmed by mass spectrometry directly from the positive blood culture, as previously reported. The amplified gene has been deposited in GenBank under accession number KT591873. In spite of the reported aggressive nature of NE, clinical remission was promptly obtained, there being no requirement for surgery.
Department of Cardiology, University Hospital P. Giaccone, Palermo, Italy.
Parrinello
P
Rossella
Department of Cardiology, University Hospital P. Giaccone, Palermo, Italy.
Carità
0000-0002-9583-9575
C
Patrizia
Department of Cardiac Surgery, University Hospital P. Giaccone, Palermo, Italy.
Triolo
T
Fabio Oreste
Department of Cardiology, University Hospital P. Giaccone, Palermo, Italy.
Trapani
T
Renato
Department of Radiology, University Hospital P. Giaccone, Palermo, Italy.
Grassedonio
G
Emanuele
Department of Cardiac Surgery, University Hospital P. Giaccone, Palermo, Italy.
Argano
A
Vincenzo
Department of Cardiology, University Hospital P. Giaccone, Palermo, Italy.
Novo
N
Giuseppina
Department of Cardiology, University Hospital P. Giaccone, Palermo, Italy.
Vallone
V
Silvana
Department of Sciences for Health Promotion and Mother and Child Care "G. D'Alessandro", University Hospital P. Giaccone, Palermo, Italy.
Fasciana
F
Teresa
Department of Radiology, University Hospital G. D'Annunzio, Chieti, Italy.
Verdecchia
V
Massimo
Department of Sciences for Health Promotion and Mother and Child Care "G. D'Alessandro", University Hospital P. Giaccone, Palermo, Italy.
Giammanco
G
Anna
Department of Radiology, University Hospital P. Giaccone, Palermo, Italy.
Midiri
M
Massimo
Department of Cardiology, University Hospital P. Giaccone, Palermo, Italy.
Novo
N
Salvatore