Gallium-68 in Medical Imaging.
Over the past several years, Positron Emission Tomography (PET) imaging agents labeled with ;68Gallium (68Ga) have undergone a significant increase in clinical utilization. 68Ga is conveniently produced from a germanium-68/gallium-68 (68Ge/68Ga) generator. Because of the compact size and ease of use of the generator, 68Ga labeled compounds may be more cost-effective than PET radioisotopes that are cyclotron-produced. The convenient half-life of 68Ga (T1/2=68 min) provides sufficient radioactivity for various PET imaging applications, while delivering acceptable radiation doses to patients. This chapter summarizes the emerging clinical utilization of 68Ga-based radiotracers in medical imaging.
Lucia
L
Martiniova
Louis De
L
Palatis
Elba
E
Etchebehere
University of Texas MD Anderson Cancer Center, 1400 Pressler, Unit Number: 1483, Houston, TX 7703, USA.
Gregory
G
Ravizzini
D005710:Gallium Radioisotopes / Q000737:chemistry* / Q000494:pharmacology*; D006207:Half-Life; D006801:Humans; D049268:Positron-Emission Tomography / Q000379:methods*; D011829:Radiation Dosage; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
D005710:Gallium Radioisotopes; D019275:Radiopharmaceuticals
68Gallium; PSMA.; generator; neuroendocrine tumors; positron emission tomography; somatostatin receptor scintigraphy