Validation of noninvasive hemoglobin measurements using co-oximetry in anesthetized dogs.
New technology allows noninvasive measurement of total hemoglobin (Hb) in humans through use of multiple wavelength co-oximetry. This monitor is now available to the veterinary market but no studies have been performed to validate its use in animals. This study investigated the use of co-oximetry to measure Hb in anesthetized dogs by comparing "gold standard" Hb measurements from a laboratory (LabHb) with those measured by the co-oximeter (SpHb). Bland-Altman analysis showed that the monitor had a bias of -3.01 (SpHb values were lower than LabHb values) and that 64.5% of measured SpHb values were greater than 20 g/L different from their associated LabHb values. Based on the results of this study, use of co-oximetry to measure Hb in anesthetized dogs is not accurate enough to direct treatment. Further studies are warranted in other animal species and under other clinical conditions.
Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6.
Matt R
MR
Read
Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6.
Jenna
J
Rondeau
Department of Veterinary Clinical and Diagnostic Sciences, University of Calgary Faculty of Veterinary Medicine, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6.
Grace P S
GP
Kwong
D000758:Anesthesia / Q000662:veterinary; D000818:Animals; D004285:Dogs; D005260:Female; D006454:Hemoglobins / Q000032:analysis*; D008297:Male; D008991:Monitoring, Physiologic / Q000662:veterinary; D010092:Oximetry / Q000662:veterinary*; D015203:Reproducibility of Results
D006454:Hemoglobins