Complementary Sources of Protein Functional Information: The Far Side of GO.
The GO captures many aspects of functional annotations, but there are other alternative complementary sources of protein function information. For example, enzyme functional annotations are described in a range of resources from the Enzyme Commission (E.C.) hierarchical classification to the Kyoto Encyclopedia of Genes and Genomes (KEGG) to the Catalytic Site Atlas amongst many others. This chapter describes some of the main resources available and how they can be used in conjunction with GO.
Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 1HT, UK. Nick.Furnham@lshtm.ac.uk.
Nicholas
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Furnham
D000818:Animals; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D004798:Enzymes / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D063990:Gene Ontology; D016678:Genome; D006801:Humans; D020407:Internet; D058977:Molecular Sequence Annotation / Q000379:methods; D000072417:Protein Domains; D060066:Protein Interaction Maps; D011506:Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D015398:Signal Transduction; D012984:Software
D004798:Enzymes; D011506:Proteins
Enzyme Commission (EC); Function similarity; Pathway annotation; Protein domain functions