Associations between sleep duration and abnormal serum lipid levels: data from the Korean National Health and Nutrition Examination Survey (KNHANES).
Shorter or longer sleep duration has been reported to be associated with abnormal serum lipid levels, but the findings have been inconsistent. This study examined associations between sleep duration and abnormal serum lipid levels in a Korean adult population.



This study used the data of 13,609 people aged ≥20 years from the Korean National Health and Nutrition Examination Survey (KNHANES) in 2010-2012. Sleep duration was classified into five groups: ≤5, 6, 7 (reference category), 8, and ≥9 hours. The serum concentrations of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride were measured and defined in terms of abnormal serum lipid levels. Multiple logistic regressions were performed to determine the associations between sleep duration and abnormal serum lipid levels. The covariates included age, sex, education, marital status, current smoking, alcohol consumption, physical activity, body mass index, hypertension, diabetes, depressive symptoms, and stress level.



Self-reported sleep duration of ≤5 hours was significantly associated with high TC and high LDL-C levels in unadjusted models, but after adjusting for age and sex, the statistical significance disappeared. On the other hand, after adjusting for covariates, self-reported sleep duration of ≥9 h was significantly associated with low HDL-C levels (odds ratio = 1.30; 95% confidence interval = 1.09-1.54).



These findings suggest that longer sleep duration is associated with low HDL-C levels among Korean adults.
Department of Biomedical Science, Chonnam National University Medical School, Gwangju, Republic of Korea.
Hee-Young
HY
Shin
Division of Clinical Pharmacology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Gaeun
G
Kang
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.
Sung-Wan
SW
Kim
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.
Jae-Min
JM
Kim
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.
Jin-Sang
JS
Yoon
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea. Electronic address: isshin@chonnam.ac.kr.
Il-Seon
IS
Shin
D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D056910:Republic of Korea; D012890:Sleep / Q000502:physiology*; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol
Cholesterol; Dyslipidemia; Korea; Lipid; Sleep