Endoscopic ultrasound-guided techniques for diagnosing pancreatic mass lesions: Can we do better?
The diagnostic approach to a possible pancreatic mass lesion relies first upon various non-invasive imaging modalities, including computed tomography, ultrasound, and magnetic resonance imaging techniques. Once a suspect lesion has been identified, tissue acquisition for characterization of the lesion is often paramount in developing an individualized therapeutic approach. Given the high prevalence and mortality associated with pancreatic cancer, an ideal approach to diagnosing pancreatic mass lesions would be safe, highly sensitive, and reproducible across various practice settings. Tools, in addition to radiologic imaging, currently employed in the initial evaluation of a patient with a pancreatic mass lesion include serum tumor markers, endoscopic retrograde cholangiopancreatography, and endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). EUS-FNA has grown to become the gold standard in tissue diagnosis of pancreatic lesions.
Andrew C Storm, Linda S Lee, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, United States.
Andrew C
AC
Storm
Andrew C Storm, Linda S Lee, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, United States.
Linda S
LS
Lee
D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods; D004724:Endoscopy / Q000379:methods*; D019160:Endosonography / Q000379:methods; D019317:Evidence-Based Medicine / Q000379:methods; D006470:Hemorrhage / Q000000981:diagnostic imaging; D006801:Humans; D007239:Infections / Q000000981:diagnostic imaging; D009367:Neoplasm Staging / Q000379:methods; D010179:Pancreas / Q000000981:diagnostic imaging; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging*; D010195:Pancreatitis / Q000000981:diagnostic imaging; D015995:Prevalence; D016032:Randomized Controlled Trials as Topic; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods*
Endoscopic ultrasound; Endoscopy; Fine needle aspiration; Pancreatic cancer; Pancreatic mass