Pancreatic Cancer Survival Outcomes at a Tertiary Medical Center Based on Sex and Geographic Location.
To describe the survival outcomes of patients with histologically proven primary pancreatic cancer based on geographic location and sex.



We conducted a retrospective review of medical records from 2009 through 2013 of patients with pancreatic cancer usingInternational Classification of Diseases, Ninth Revisioncode 157.9 andInternational Statistical Classification of Diseases, 10th Revisioncode C 25.9. The variables extracted included demographics, date of diagnosis, mode of diagnosis, duration, treatment methods, family history, history of chronic pancreatitis, and diabetes mellitus. ZIP codes were used to identify the geographic location of each subject, and rural urban commuting area codes were used to further classify the areas as metropolitan, micropolitan, small town, and rural. Population sizes were classified as metropolitan >50,000, micropolitan 10,000 to 49,999, small town 2500 to 9999, and rural <2500. Descriptive analysis and Kaplan-Meier survival for survival outcomes were performed with statistical significance identified asP< 0.05.



A total of 400 medical charts were extracted for review, 301 of which belonged to patients with primary pancreatic cancer. Of the 301 cases, we identified 175 men (58%), 125 women (41%), and 1 missing sex data. There were 280 whites (95%), 8 African Americans (2%), 2 Asian Americans (0.64%), 1 Hispanic American (0.34%) and 1 Native American (0.34%), with a mean age of 63.2 ± 12.6 years. Based on geography, there were 34%, 27%, 20%, and 19% in rural areas, metropolitans, small towns, and micropolitans, respectively. No statistically significant difference was noted in sex on survival outcomes (P= 0.85) or geography (P= 0.62). Additional analysis revealed no statistical significant difference between sexes when stratifying by location (P= 0.96).



There is no difference in survival outcomes of patients with primary pancreatic cancer based on sex or geographic location. Our survival outcomes differ from the national survival outcomes, which reveal that mortality in men is higher than it is in women.
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Anjana
A
Sathyamurthy
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Harleen
H
Chela
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Bhupinder
B
Romana
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Mohamad
M
Yousef
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Jessica
J
Winn
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Richard
R
Madsen
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Matthew
M
Bechtold
From the Division of Gastroenterology and Hepatology and Departments of Internal Medicine and Statistics, University of Missouri-Columbia School of Medicine, Columbia.
Akwi W
AW
Asombang
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology; D002277:Carcinoma / Q000401:mortality / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000401:mortality* / Q000473:pathology; D044469:Racial Groups / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012424:Rural Population / Q000706:statistics & numerical data; D017678:Sex Distribution; D013383:Suburban Population / Q000706:statistics & numerical data; D062606:Tertiary Care Centers; D014481:United States / Q000453:epidemiology; D014505:Urban Population / Q000706:statistics & numerical data