Metastatic Crohn disease clinically reminiscent of erythema nodosum on the right leg.
Cutaneous manifestations are well-recognized complications of Crohn disease (CD) that can be divided into disease-specific and reactive conditions. One of the most common reactive conditions is erythema nodosum (EN), which presents as subcutaneous tender nodules most often on the legs. On the other hand, metastatic Crohn disease (MCD) is a rare cutaneous manifestation of CD defined as the presence of noncaseating granulomas that are not contiguous with the gastrointestinal (GI) tract. The clinical presentation of MCD is variable; however, lesions often are located on the legs and genital region. We report the case of a 21-year-old woman with a 6-year history of CD who presented with MCD clinically simulating EN.
Department of Dermatology, Hanyang University Hospital, College of Medicine, Seoul, Korea.
Hyun C
HC
Park
Department of Dermatology, Hanyang University Hospital, College of Medicine, Seoul, Korea.
Hyun W
HW
Kim
Department of Pathology, Hanyang University Hospital, College of Medicine, Seoul, Korea.
Chan G
CG
Park
Department of Dermatology, Hanyang University Hospital, College of Medicine, Seoul, Korea.
Joo Y
JY
Ko
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D003113:Colonoscopy / Q000379:methods; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D004893:Erythema Nodosum / Q000175:diagnosis*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006099:Granuloma / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D007866:Leg; D019804:Mesalamine / Q000008:administration & dosage*; D008795:Metronidazole / Q000008:administration & dosage*; D012867:Skin / Q000473:pathology*; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D008795:Metronidazole; D019804:Mesalamine