The real-time fMRI neurofeedback based stratification of Default Network Regulation Neuroimaging data repository.
This data descriptor describes a repository of openly shared data from an experiment to assess inter-individual differences in default mode network (DMN) activity. This repository includes cross-sectional functional magnetic resonance imaging (fMRI) data from the Multi Source Interference Task, to assess DMN deactivation, the Moral Dilemma Task, to assess DMN activation, a resting state fMRI scan, and a DMN neurofeedback paradigm, to assess DMN modulation, along with accompanying behavioral and cognitive measures. We report technical validation from n=125 participants of the final targeted sample of 180 participants. Each session includes acquisition of one whole-brain anatomical scan and whole-brain echo-planar imaging (EPI) scans, acquired during the aforementioned tasks and resting state. The data includes several self-report measures related to perseverative thinking, emotion regulation, and imaginative processes, along with a behavioral measure of rapid visual information processing. Technical validation of the data confirms that the tasks deactivate and activate the DMN as expected. Group level analysis of the neurofeedback data indicates that the participants are able to modulate their DMN with considerable inter-subject variability. Preliminary analysis of behavioral responses and specifically self-reported sleep indicate that as many as 73 participants may need to be excluded from an analysis depending on the hypothesis being tested. The present data are linked to the enhanced Nathan Kline Institute, Rockland Sample and builds on the comprehensive neuroimaging and deep phenotyping available therein. As limited information is presently available about individual differences in the capacity to directly modulate the default mode network, these data provide a unique opportunity to examine DMN modulation ability in relation to numerous phenotypic characteristics.
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Amalia R
AR
McDonald
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Jordan
J
Muraskin
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Child Mind Institute, New York, NY, USA.
Nicholas T Van
NTV
Dam
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Caroline
C
Froehlich
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Benjamin
B
Puccio
Child Mind Institute, New York, NY, USA.
John
J
Pellman
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Boston, MA, USA.
Clemens C C
CCC
Bauer
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Alexis
A
Akeyson
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Melissa M
MM
Breland
The Mind Research Network, Albuquerque, New Mexico, USA; Department of Electrical and Computer Engineering, The University of New Mexico, Albuquerque, New Mexico, USA.
Vince D
VD
Calhoun
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Steven
S
Carter
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Tiffany P
TP
Chang
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Chelsea
C
Gessner
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Alyssa
A
Gianonne
Child Mind Institute, New York, NY, USA.
Steven
S
Giavasis
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Jamie
J
Glass
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Steven
S
Homann
The Mind Research Network, Albuquerque, New Mexico, USA.
Margaret
M
King
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Melissa
M
Kramer
The Mind Research Network, Albuquerque, New Mexico, USA.
Drew
D
Landis
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Alexis
A
Lieval
Virginia Tech Carilion Research Institute, Roanoke, VA, USA.
Jonathan
J
Lisinski
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Columbia University, Cognitive Neuroscience Division, Taub Institute and GH Sergeivesky Center, New York, NY, USA.
Anna
A
Mackay-Brandt
The Mind Research Network, Albuquerque, New Mexico, USA.
Brittny
B
Miller
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Laura
L
Panek
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Hayley
H
Reed
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Christine
C
Santiago
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Eszter
E
Schoell
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Richard
R
Sinnig
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Melissa
M
Sital
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Elise
E
Taverna
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Russell
R
Tobe
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Kristin
K
Trautman
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Betty
B
Varghese
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Lauren
L
Walden
The Mind Research Network, Albuquerque, New Mexico, USA.
Runtang
R
Wang
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Abigail B
AB
Waters
The Mind Research Network, Albuquerque, New Mexico, USA.
Dylan C
DC
Wood
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; The Child Study Center, NYU Langone Medical Center, New York, NY, USA.
F Xavier
FX
Castellanos
Department of Psychiatry, University of California - San Francisco, San Francisco, CA, USA.
Bennett
B
Leventhal
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
Stanley J
SJ
Colcombe
Virginia Tech Carilion Research Institute, Roanoke, VA, USA; School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA; Departments of Emergency Medicine and Emergency Radiology, Virginia Tech Carilion School of Medicine, Roanoke, VA, USA.
Stephen
S
LaConte
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Child Mind Institute, New York, NY, USA.
Michael P
MP
Milham
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Child Mind Institute, New York, NY, USA. Electronic address: ccraddock@nki.rfmh.org.
R Cameron
RC
Craddock
D000328:Adult; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D016208:Databases, Factual; D017352:Echo-Planar Imaging; D005260:Female; D006801:Humans; D007206:Individuality; D033181:Information Dissemination; D016247:Information Storage and Retrieval; D008279:Magnetic Resonance Imaging; D008297:Male; D001523:Mental Disorders / Q000503:physiopathology*; D008875:Middle Aged; D009434:Neural Pathways; D058765:Neurofeedback; D059906:Neuroimaging; D010641:Phenotype; D055815:Young Adult
Data sharing; Default mode network; Functional MRI; Neurofeedback; Real-time fMRI