Could Mean Platelet Volume Be a Reliable Indicator for Acute Mesenteric Ischemia Diagnosis? A Case-Control Study.
Objective. Acute mesenteric ischemia (AMI) is a disease, usually seen in elderly people and accompanied by comorbid diseases. Mean platelet volume (MPV), the significant indicator of platelet activation and function, is associated with AMI. In this study, we considered that we can use MPV as a reliable indicator in the diagnosis of AMI.Methods. This study was conducted among AMI patients with two control groups. Age, gender, MPV, platelet count, concomitant diseases, abdominal computed tomography, and patient outcomes were recorded for evaluation. Control group I contained 41 healthy patients whose ages-genders were matched. Control group II contained 41 patients with no AMI, whose ages-genders-concomitant diseases were matched.Results. Of the total 41 AMI patients, 22 were female and 19 were male. The average age of them was 72.12 ± 13.2 (44-91) years. MPV was significantly increased in the AMI (p= 0.001) and control group II (p< 0.001) in comparison with healthy control groups. In the comparison of the AMI patients with their matched controls for concomitant diseases, no statistical difference was found in the MPV values.Conclusion. MPV may be used as an indicator of AMI only if the patient has no concomitant diseases. The existence of a concomitant disease brings into question the reliability of high MPV values as a suitable indicator.
Department of Emergency Medicine, Izmir Bozyaka Training and Research Hospital, Bozyaka, Izmir, Turkey.
Vermi
V
Degerli
Department of Public Health, Ege University School of Medicine, Bornova, Izmir, Turkey.
Isil
I
Ergin
Department of Anaesthesiology and Reanimation, Izmir Bozyaka Training and Research Hospital, Bozyaka, Izmir, Turkey.
Fulya Yilmaz
0000-0002-6901-7404
FY
Duran
Department of Surgery, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Yenimahalle, 06200 Ankara, Turkey.
Mehmet Akif
MA
Ustuner
Department of Emergency Medicine, Izmir Bozyaka Training and Research Hospital, Bozyaka, Izmir, Turkey.
Ozgur
O
Duran
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D065666:Mesenteric Ischemia / Q000097:blood* / Q000473:pathology; D008875:Middle Aged
D015415:Biomarkers