Ofuji disease: a rare dermatosis and its challenging therapeutic approach.
Eosinophilic pustular folliculitis (EPF) or Ofuji disease is a rare dermatosis, prone to recurrence and chronicity. The peak incidence occurs in the third decade of life and its exact etiology remains unknown. Evidence suggests that the expression of adhesion molecules and the production of cytokines activate the follicular unit, but the stimulus that triggers these changes remains unclear. The three clinical variants reported in the literature include classic EPF, immunosuppression-associated EPF, and infancy-associated EPF. We report a case of eosinophilic pustular folliculitis with peculiar epidemiological characteristics, which represents a challenging therapeutic scenario.
Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
Fernanda Freitas de
FF
Brito
Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
Antonio Carlos Ceribelli
AC
Martelli
Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
Maria Lopes Lamenha Lins
ML
Cavalcante
Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
Ana Cecília Versiani Duarte
AC
Pinto
Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
Gabriela
G
Itimura
Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
Cleverson Teixeira
CT
Soares
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004802:Eosinophilia / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005499:Folliculitis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006098:Granulocytes / Q000473:pathology; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications; D012008:Recurrence; D012872:Skin Diseases, Vesiculobullous / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007213:Indomethacin