Ovarian endometriosis and vitamin D serum levels.
OBJECTIVE
The aim of this study was to assess the vitamin D serum level in women with ovarian endometriosis; specifically, a possible correlation between the dimensions of ovarian endometriomas and vitamin D serum levels was evaluated.


METHODS
This was an observational study of childbearing-age women diagnosed with singleton ovarian endometrioma from January 2015 to December 2015. Women diagnosed with multiple ovarian endometriomas or extraovarian endometriosis were excluded.


RESULTS
Forty-nine women constituted the initial study cohort. In these women, the mean (±SD) 25-OH-D3 serum level was 22.0 (±8.9) ng/ml, and 42 of them (85.7%) were diagnosed with hypovitaminosis D. In the "hypovitaminosis D women", the mean (± SD) diameter of ovarian endometriomas was 40.2 ± 22.6 mm, while in the "normal vitamin D serum level women" it was 26.7 ± 12.1 mm (p = 0.1). However, a significant linear correlation between 25-OH-D3 serum level and the diameter of ovarian endometriomas was found (r = -0.3, p = 0.03).


CONCLUSIONS
We found a relatively high rate of women with ovarian endometriosis and hypovitaminosis D. Interestingly, a significant linear correlation between 25-OH-D3 serum levels and the diameter of ovarian endometrioma emerged.
a Woman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche , Ancona , Italy.
Andrea
A
Ciavattini
a Woman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche , Ancona , Italy.
Matteo
M
Serri
a Woman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche , Ancona , Italy.
Giovanni
G
Delli Carpini
a Woman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche , Ancona , Italy.
Stefano
S
Morini
a Woman's Health Sciences Department, Gynecologic Section, Polytechnic University of Marche , Ancona , Italy.
Nicolò
N
Clemente
D000328:Adult; D002112:Calcifediol / Q000097:blood*; D015331:Cohort Studies; D004715:Endometriosis / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010049:Ovarian Diseases / Q000097:blood*; D014808:Vitamin D Deficiency / Q000097:blood*
D002112:Calcifediol
Endometriosis; hypovitaminosis D; ovarian endometrioma; vitamin D