An overview of psoriatic arthritis - epidemiology, clinical features, pathophysiology and novel treatment targets.
Psoriatic arthritis is a chronic inflammatory joint disease occurring in a subgroup of patients suffering from psoriasis. This article gives an overview of the complexity of psoriatic arthritis, looking at several aspects of this heterogeneous disease, such as epidemiology, important clinical features and comorbidities as well as current concepts of the pathophysiology and subsequent insights in novel treatment targets.
Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. andreas.kerschbaumer@meduniwien.ac.at.|Karl Landsteiner Institute for Autoimmune Diseases and Rheumatology, Kundratstraße 3, 1100, Vienna, Austria. andreas.kerschbaumer@meduniwien.ac.at.
Andreas
A
Kerschbaumer
Karl Landsteiner Institute for Autoimmune Diseases and Rheumatology, Kundratstraße 3, 1100, Vienna, Austria.
Karl H
KH
Fenzl
Karl Landsteiner Institute for Autoimmune Diseases and Rheumatology, Kundratstraße 3, 1100, Vienna, Austria.|2nd Medical Department with Rheumatology, Osteology and Geriatrics, Kundratstraße 3, 1100, Vienna, Austria.
Ludwig
L
Erlacher
Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Daniel
D
Aletaha
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D015535:Arthritis, Psoriatic / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D015897:Comorbidity; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D006801:Humans; D015994:Incidence; D007249:Inflammation / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D058990:Molecular Targeted Therapy / Q000379:methods; D012307:Risk Factors; D063189:Symptom Assessment / Q000379:methods*; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents
Clinical aspects; Epidemiology; Pathophysiology; Psoriatic arthritis; Treatment