Diffuse type testicular seminoma in a stallion.
A 7-year-old stallion with progressive left testicular enlargement was presented. Grossly, the excised testicle measured 25 × 15 × 12 cm and weighed 3.7 kg. It was multinodular with a gray-white surface; however, the right testis was normal. Histologically, the neoplastic cells were disseminated diffusely in the tumoral stroma with a minimal fibrovascular stroma. Neoplastic cells were round to polygonal with abundant eosinophilic cytoplasm and large round to oval vesicular or hyperchromatic nucleous with a single prominent nucleolus. Immunohistochemically, the neoplastic cells were positive nuclear immunostaining for C-KIT and negative for OCT3/4. According to gross, histopathological, and immunohistochemical characteristics, the diffuse type of seminoma was diagnosed. Nine months later, the follow-up observation of the case showed that the tumor had no recurrence and metastasis.
Department of Pathobiology, Faculty of Veterinary Medicine, Lorestan University, Khorram Abad, Iran.
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Farjanikish
Department of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
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Sayari
Department of Clinical Studies, Faculty of Veterinary Medicine, Lorestan University, Khorram Abad, Iran.
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A
Raisi
Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran ; Shiraz Molecular Pathology Research Centre, Dr. Daneshbod Laboratory, Shiraz, Iran.
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Shirian
Histopathology; Immunohistochemistry; Seminoma; Stallion