Neutrophil Lymphocyte Ratio as a Predictor of Left Ventricular Apical Thrombus in Patients with Myocardial Infarction.
OBJECTIVE
In this study, we examined the role of inflammatory parameters in an apical mural thrombus with a reduced ejection fraction due to large anterior myocardial infarction (MI).


METHODS
A total of 103 patients who had suffered from heart failure, 45 of whom had left ventricular apical thrombus (AT) after a large anterior MI, were enrolled in the study. A detailed clinical history was taken of each participant, biochemical inflammatory markers, which were obtained during admission, were analyzed and an echocardiographical and angiographical evaluation of specific parameters were performed.


RESULTS
There were no statistically significant differences in terms of age, gender, and history of hypertension, diabetes mellitus, and atrial fibrillation between both groups (p>0.05). Similarly there were no statistically significant differences in terms of biochemical and echocardiographic parameters (p>0.05). However, there were significant differences in terms of neutrophil lymphocyte ratio (p=0.032). After a multivariate regression analysis, neutrophil lymphocyte ratio (NLR) was an independent predictor of thrombus formation (β: 0.296, p=0.024). The NLR >2.74 had a 78% sensivity and 61% specifity in predicting thrombus in patients with a low left ventricular ejection fraction.


CONCLUSIONS
In this study, neutrophil lymphocyte ratios were significantly higher in patients with apical thrombus.
Department of Cardiology, Ataturk Training and Research Hospital, Ankara, Turkey.
Ahmet Goktug
AG
Ertem
Department of Cardiology, Ataturk Training and Research Hospital, Ankara, Turkey.
Filiz
F
Ozcelik
Department of Cardiology, Yildirim Beyazit University, Ankara, Turkey.
Haci Ahmet
HA
Kasapkara
Department of Cardiology, Ataturk Training and Research Hospital, Ankara, Turkey.
Cemal
C
Koseoglu
Department of Cardiology, Ataturk Training and Research Hospital, Ankara, Turkey.
Serdal
S
Bastug
Department of Cardiology, Yildirim Beyazit University, Ankara, Turkey.
Huseyin
H
Ayhan
Department of Cardiology, Ataturk Training and Research Hospital, Ankara, Turkey.
Cenk
C
Sari
Department of Cardiology, Yildirim Beyazit University, Ankara, Turkey.
Nihal
N
Akar Bayram
Department of Cardiology, Ataturk Training and Research Hospital, Ankara, Turkey.
Emine
E
Bilen
Department of Cardiology, Yildirim Beyazit University, Ankara, Turkey.
Tahir
T
Durmaz
Department of Cardiology, Yildirim Beyazit University, Ankara, Turkey.
Telat
T
Keles
Department of Cardiology, Yildirim Beyazit University, Ankara, Turkey.
Engin
E
Bozkurt
Inflammation; Myocardial infarction; Thrombus