The Complete Response to Targeted Drugs Without Surgery or Radiotherapy: A Case of Pituitary Metastasis From Renal Cell Carcinoma.
Pituitary gland metastasis was seen in elderly patients, and the incidence of pituitary metastasis is 1% to 4% of all cancer patients. Renal cell carcinoma is a primary malignancy in only 2.6% of pituitary metastases. We reported a 50-year-old man with pituitary metastasis from renal cell carcinoma that had signs of diabetes insipidus. He had multiple lesions in both lungs, and bone scan involved L12 and L1 vertebrates. He was treated with combination bevacizumab 600 mg/month and sunitinib 50 mg/D for four weeks with two weeks rest for 6 months. Treatment with targeted drugs without surgery of pituitary or radiotherapy improved metastatic renal cell carcinoma in the patient.
Department of Hematology-Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mehrdad
M
Payandeh
Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Masoud
M
Sadeghi
Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Edris
E
Sadeghi
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000473:pathology; D003919:Diabetes Insipidus / Q000209:etiology; D006801:Humans; D007211:Indoles / Q000008:administration & dosage; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010902:Pituitary Gland / Q000473:pathology; D010911:Pituitary Neoplasms / Q000188:drug therapy* / Q000556:secondary; D011758:Pyrroles / Q000008:administration & dosage; D000077210:Sunitinib
D007211:Indoles; D011758:Pyrroles; D000077210:Sunitinib
Diabetes insipidus; Pituitary metastasis; Renal cell carcinoma; Sunitinib