Should we resect peri-lesional hemosiderin deposits when performing lesionectomy in patients with cavernoma-related epilepsy (CRE)?
In this review, the authors perform a database search and summarize and discuss all eligible studies that provide (subgroup) analysis of the postoperative seizure outcome of patients with cavernoma-related epilepsy undergoing sole lesionectomy or lesionectomy including the hemosiderin rim. Based on the currently available data, the authors conclude that if surgical treatment of cavernoma-related epilepsy is performed, the peri-lesional hemosiderin should be resected. However, cases of eloquent or multiple localization or widespread hemosiderin deposit in which a complete resection is challenging should undergo a specific preoperative work-up.
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45121, Essen, Germany. philipp.dammann@uk-essen.de.|Department of Neurosurgery, University Hospital Geneva, Geneva, Switzerland. philipp.dammann@uk-essen.de.
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P
Dammann
Department of Neurosurgery, University Hospital Geneva, Geneva, Switzerland.
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C
Schaller
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45121, Essen, Germany.
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U
Sure
D001921:Brain / Q000601:surgery*; D004827:Epilepsy / Q000601:surgery*; D006392:Hemangioma, Cavernous / Q000601:surgery*; D006485:Hemosiderin / Q000378:metabolism*; D006801:Humans; D011184:Postoperative Period; D016896:Treatment Outcome
D006485:Hemosiderin
CCM; CRE; Cavernoma; Cavernous malformation; Epilepsy; Hemosiderin