Differentiation of recurrent spinal ependymoma from postradiation treatment necrosis through multiparametric PET-MR and perfusion MRI.
A 67-year-old male presented with papilledema and back pain localized to the T10 level. Initial workup revealed multifocal spinal ependymoma which was resected and treated with external beam radiotherapy. Nine years after treatment, the patient had a relapse of back pain, and MRI was inconclusive in distinguishing posttreatment radiation necrosis from recurrent tumor. We present the first described report with the utilization of multiparametric positron emission tomography-magnetic resonance imaging and perfusion MRI to distinguish recurrent spinal ependymoma from radiation necrosis.
Diagnostic Neuroradiology, Department of Radiology, Cleveland, OH.
Mojgan
M
Hojjati
Diagnostic Neuroradiology, Department of Radiology, Cleveland, OH.
Vasant
V
Garg
Diagnostic Neuroradiology, Department of Radiology, Cleveland, OH.
Chaitra A
CA
Badve
Diagnostic Neuroradiology, Department of Radiology, Cleveland, OH.
Salim E
SE
Abboud
Department of Neurosurgery, Cleveland, OH.
Andrew E
AE
Sloan
Diagnostic Neuroradiology, Department of Radiology, Cleveland, OH. Electronic address: Leo.Wolansky@UHHospitals.org.
Leo J
LJ
Wolansky
D000368:Aged; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging; D009336:Necrosis / Q000000981:diagnostic imaging; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D011832:Radiation Injuries; D019275:Radiopharmaceuticals; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
Multiparametric PET-MRI; Perfusion MRI; Radiation necrosis; Spinal ependymoma