Cre Recombinase Strains Used for the Study of Adipose Tissues and Adipocyte Progenitors.
Adipose tissues play important roles in whole body energy homeostasis and lifer span. Understanding the mechanisms of controlling adipose tissues development is significant for providing useful information to treat the worldwide epidemic of obesity and its associated metabolic diseases. Several different Cre transgenes have been generated and used for determining the origin of adipose tissues and the function of individual gene in regulating adipose growth and development. Here, we mainly review and discuss the efficiency and specific of those Cre recombinase mouse strains used for the study of adipose tissues and adipocyte progenitors. J. Cell. Physiol. 232: 2698-2703, 2017. © 2016 Wiley Periodicals, Inc.
College of Animal Sciences, Zhejiang University; The Key Laboratory of Molecular Animal Nutrition, Ministry of Education; Zhejiang Provincial Laboratory of Feed and Animal Nutrition, Hangzhou, Zhejiang, China.
Jiaqi
J
Liu
College of Animal Sciences, Zhejiang University; The Key Laboratory of Molecular Animal Nutrition, Ministry of Education; Zhejiang Provincial Laboratory of Feed and Animal Nutrition, Hangzhou, Zhejiang, China.
Ziye
Z
Xu
College of Animal Sciences, Zhejiang University; The Key Laboratory of Molecular Animal Nutrition, Ministry of Education; Zhejiang Provincial Laboratory of Feed and Animal Nutrition, Hangzhou, Zhejiang, China.
Weiche
W
Wu
College of Animal Sciences, Zhejiang University; The Key Laboratory of Molecular Animal Nutrition, Ministry of Education; Zhejiang Provincial Laboratory of Feed and Animal Nutrition, Hangzhou, Zhejiang, China.
Yizhen
Y
Wang
College of Animal Sciences, Zhejiang University; The Key Laboratory of Molecular Animal Nutrition, Ministry of Education; Zhejiang Provincial Laboratory of Feed and Animal Nutrition, Hangzhou, Zhejiang, China.
Tizhong
T
Shan
D017667:Adipocytes / Q000378:metabolism / Q000502:physiology*; D050156:Adipogenesis; D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D019070:Cell Lineage; D018507:Gene Expression Regulation, Developmental; D005819:Genetic Markers; D006801:Humans; D019426:Integrases / Q000235:genetics* / Q000378:metabolism; D008822:Mice, Transgenic; D010641:Phenotype; D013234:Stem Cells / Q000378:metabolism / Q000502:physiology*; D019076:Transgenes
D005819:Genetic Markers; C045073:Cre recombinase; D019426:Integrases