Preliminary Study on theIn vitroandIn vivoEffects ofAsparagopsis taxiformisBioactive Phycoderivates on Teleosts.
Several compounds from marine organisms have been studied for their potential use in aquaculture. Among the red algae,Asparagopsis taxiformisis considered one of the most promising species for the production of bioactive metabolites with numerous proposed applications. Here, thein vitroantibacterial activity, the easy handling and the absence of adverse effects on marine fish species are reported. Depending on the seasonal period of sampling, ethanol extracts ofA. taxiformisexhibited significantly different inhibitory activity against fish pathogenic bacteria. The extract obtained in late spring showed strong antibacterial activity againstAeromonas salmonicidasubsp.salmonicida, Vibrio alginolyticus, andV. vulnificus, and moderate activity againstPhotobacterium damselaesubsp.damselae, P. damselaesubsp.piscicida, V. harveyiandV. parahaemolyticus. Sea bass and gilthead sea bream were fed with pellets supplied with the alga and algal extracts. The absence of undesired effects on fish was demonstrated. Hematological and biochemical investigations allowed to confirm that the whole alga and its extracts could be proposed for a future application in aquaculture.
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Fabio
F
Marino
Department of Veterinary Sciences, University of Messina Messina, Italy.
Gianfranco
G
Di Caro
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Concetta
C
Gugliandolo
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Antonio
A
Spanò
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Caterina
C
Faggio
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Giuseppa
G
Genovese
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Marina
M
Morabito
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Annamaria
A
Russo
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina Messina, Italy.
Davide
D
Barreca
Department of Veterinary Sciences, University of Messina Messina, Italy.
Francesco
F
Fazio
Laboratory of Marine Biochemistry and Ecotoxixology, Department of Earth and Sea Sciences, University of Palermo Trapani, Italy.
Andrea
A
Santulli
Asparagopsis taxiformis; Dicentrarchus labrax; Sparus aurata; antibacterial activity; hematological parameters; oxidative stress; toxicity