Coexisting Cardiac and Hematologic Disorders.
Patients with concomitant cardiac and hematologic disorders presenting for noncardiac surgery are challenging. Anemic patients with cardiac disease should be approached in a methodical fashion. Transfusion triggers and target should be based on underlying symptomatology. The approach to anticoagulation management in patients with artificial heart valves, cardiac devices, or severe heart failure in the operative setting must encompass a complete understanding of the rationale of a patient's therapy as well as calculate the risk of changing this regimen. This article focuses common disorders and discusses strategies to optimize care in patients with coexisting cardiac and hematologic disease.
Department of Anesthesiology, Sidney Kimmel Medical College, Thomas Jefferson University, 111 South 11th Street, Philadelphia, PA 19107, USA. Electronic address: Jordan.Goldhammer@Jefferson.edu.
Jordan E
JE
Goldhammer
Department of Anesthesiology, Sidney Kimmel Medical College, Thomas Jefferson University, 111 South 11th Street, Philadelphia, PA 19107, USA.
Benjamin A
BA
Kohl
D000740:Anemia / Q000150:complications; D000755:Anemia, Sickle Cell / Q000150:complications; D000925:Anticoagulants / Q000627:therapeutic use; D001791:Blood Platelet Disorders / Q000150:complications; D006331:Heart Diseases / Q000150:complications*; D006333:Heart Failure / Q000150:complications; D006353:Heart-Assist Devices; D006402:Hematologic Diseases / Q000150:complications*; D006801:Humans
D000925:Anticoagulants
Anticoagulation management of severe heart failure; Cardiac manifestations of sickle cell disease; Essential thrombocytosis; Idiopathic thrombotic purpura; Perioperative anticoagulation management of artificial heart valves; Perioperative anticoagulation management of ventricular assist devices; Perioperative transfusion threshold