Psychometric validation of the electronic chronic pain questions (eCPQ) in a primary care setting.
Collecting data that helps evaluate different types of pain may improve physicians' decision-making with regard to treatment selection and on-going monitoring of patients. To date, no chronic pain assessments have been widely implemented in primary care. The aim of this study was to psychometrically validate the electronic Chronic Pain Questions (eCPQ) in a primary care setting.



All men and women ≥18 years arriving at two similar primary care clinics in southeastern Michigan were invited to participate. Clinic staff verbally administered the eCPQ to patients and recorded their answers into the electronic medical record (EMR) prior to physician consultation with results available for physician review. Concurrent validity was assessed using Spearman correlations between eCPQ and patient-completed ancillary measures. Known-group validity was assessed by stratifying patients on self-reported chronic pain as well as by pain diagnosis (i.e. ICD-9 codes). To compare patients with chronic pain versus no chronic pain t-tests and chi-square tests were performed. Reproducibility was assessed between interviewer- and self-administration over time.



A total of 534 patients were invited to participate and 455 patients consented to take part in the study (85.2% response rate); 395 patients had analyzable eCPQ data; 70.1% were Caucasian; 68.1% female; mean age was 43.4; 52.7% (n = 208) self-reported chronic pain. Correlations between eCPQ and ancillary measures supported concurrent validity. Excellent discrimination between groups was evidenced based on self-reported chronic pain and ICD-9 diagnosis. Patients with self-reported chronic pain reported significantly (p < .0001) higher pain ratings and greater interference with usual activities, sleep, and mood than those without chronic pain. Test-retest reliability between modes (interviewer- vs. self-administration) was excellent as was reproducibility based on self-administration of the eCPQ at two separate time points. Key limitations: Discriminant validity was determined by comparing participants based on ICD codes. Utilizing ICD codes to identify individuals with chronic pain may not be a reliable approach as it is dependent upon providers accurately and consistently entering chronic pain diagnoses in the EMR.



The eCPQ has sound psychometric measurement properties, including concurrent validity, discriminant validity, and reproducibility. The eCPQ appears to be useful to identify patients with chronic pain and to assess and monitor symptoms over time.
a Outcomes Research, Evidera , Bethesda , MD , USA.
Karin S
KS
Coyne
a Outcomes Research, Evidera , Bethesda , MD , USA.
Brooke M
BM
Currie
b Pfizer Inc. , New York , NY , USA.
Sean
S
Donevan
b Pfizer Inc. , New York , NY , USA.
Marina
M
Brodsky
b Pfizer Inc. , New York , NY , USA.
Michael J
MJ
Asmus
b Pfizer Inc. , New York , NY , USA.
Daniel W
DW
Krichbaum
b Pfizer Inc. , New York , NY , USA.
Joseph C
JC
Cappelleri
b Pfizer Inc. , New York , NY , USA.
Rozelle
R
Hegeman-Dingle
b Pfizer Inc. , New York , NY , USA.
Alesia
A
Sadosky
b Pfizer Inc. , New York , NY , USA.
Samuel Z
SZ
Whipple
c Clinical Outcomes Solutions , Folkestone , UK.
Claire
C
Burbridge
d Oakland University William Beaumont School of Medicine , Rochester , MI , USA.
Elie
E
Mulhem
d Oakland University William Beaumont School of Medicine , Rochester , MI , USA.
J Bruce
JB
Hillenberg
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D059350:Chronic Pain / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011320:Primary Health Care; D011594:Psychometrics; D015203:Reproducibility of Results
Chronic pain; eCPQ; primary care; psychometric; reproducibility; validity