Renal replacement therapy in Europe-a summary of the 2010 ERA-EDTA Registry Annual Report.
BACKGROUND
This study provides a summary of the 2010 European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report (available at www.era-edta-reg.org).


METHODS
This report includes data on renal replacement therapy (RRT) using data from the national and regional renal registries in 29 countries in Europe and bordering the Mediterranean Sea. Individual patient data were received from 27 registries, whereas 18 registries contributed data in aggregated form. We present incidence and prevalence of RRT, transplant rates, survival probabilities and expected remaining lifetimes. The latter two are solely based on individual patient records.


RESULTS
In 2010, the overall incidence rate of RRT for end-stage renal disease (ESRD) among all registries reporting to the ERA-EDTA Registry was 123 per million population (pmp) (n= 91 798). The highest incidence rate was reported by Turkey (252pmp) and the lowest reported by Montenegro (21 pmp). The overall prevalence of RRT for ESRD at 31 December 2010 among all registries reporting to the ERA-EDTA Registry was 741 pmp (n= 551 005). The prevalence varied from 124 pmp in Ukraine to 1580 pmp in Portugal. The overall number of renal transplantations performed in 2010 among all registries was 29.2 pmp (n= 21 740). The highest overall transplant rate was reported from Spain, Cantabria (73 pmp), whereas the highest transplant rate for living donor kidneys was reported from the Netherlands (28 pmp). For patients who started RRT between 2001 and 2005, the unadjusted 5-year patient survival on RRT was 46.2% [95% confidence interval (CI) 46.0-46.3], and on dialysis 38.6% (95% CI 38.5-38.8). The unadjusted 5-year patient survival after the first renal transplantation performed between 2001 and 2005 was 86.6% (95% CI 86.1-87.1) for deceased donor kidneys and 94.1% (95% CI 93.4-94.8) for living donor kidneys.
ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Anneke
A
Kramer
ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Vianda S
VS
Stel
Dirección General de Planificación y Aseguramiento, Gobierno de Aragón, Spain.
José Maria
JM
Abad Diez
Dirección General de Salud Pública, Principado de Asturias, Spain.
Ramón
R
Alonso de la Torre
Oficina de Coordinación de Trasplantes, Servicio Gallego de Salud (SERGAS), Galicia, Spain.
Encarnación
E
Bouzas Caamaño
Nephrology and Dialysis Department, University Clinic for Internal Diseases, Sestre Milosrdnice Clinical Hospital Centre, School of Medicine, University of Zagreb, Zagreb, Croatia.
Svjetlana
S
Čala
Nephrology Service, Hospital del Mar, Catalonia, Barcelona, Spain.
Higini
H
Cao Baduell
Coordinación Autonómica de Trasplantes, Servicios de Apoyo del SAS, Sevilla, Andalusia, Spain.
Pablo
P
Castro de la Nuez
Department of Internal Medicine, P.Stradins Clinical University Hospital, Riga, Latvia.
Harijs
H
Cernevskis
French-Belgian ESRD Registry, Brussels, Belgium.
Frederic
F
Collart
REIN registry, Agence de la biomédecine, Saint Denis La Plaine Cedex, Paris, France.
Cécile
C
Couchoud
Dept of Nephrology, Dialysis & Hypertension, AZ Nikolaas, Sint-Niklaas, Belgium.
Johan
J
de Meester
School of Medicine, University of Belgrade, Belgrade, Serbia.
Ljubica
L
Djukanovic
Valencian Region Renal Registry (REMRENAL), Dir. Gral. Investigacion y Salud Publica, Conselleria de Sanitat, Valencia, Spain.
Manuel
M
Ferrer-Alamar
Department of Nephrology, Helsinki University Central Hospital, Helsinki, Finland; Finnish Registry for Kidney Diseases, Helsinki, Finland.
Patrik
P
Finne
Nephrology Research Group, Centre for Public Health, Queen's University and Regional Nephrology Unit, Belfast City Hospital, Belfast, UK.
Damian
D
Fogarty
Servicio Extremeño de Salud, Consejería de Salud y Política Social, Gobierno de Extremadura, Spain.
María
M
de Los Ángeles García Bazaga
Dr Carol Davila University of Medicine and Pharmacy, Dr Carol Davila Teaching Hospital of Nephrology, Bucharest, Romania.
Liliana
L
Garneata
Israel Society of Nephrology & Hypertension, Dept. of Nephrology & Hypertension, Meir Medical Center, Kfar-Saba, Israel.
Eliezer
E
Golan
Técnico de la Coordinación Autonómica de Trasplantes de Castilla y León, Spain.
Raquel
R
Gonzalez Fernández
Department of Nephrology B, Copenhagen University Hospital at Herlev, Herlev, Denmark.
James G
JG
Heaf
Department of Nephrology, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands.
Andries
A
Hoitsma
Hellenic Renal Registry, General Hospital of Athens "G.Gennimatas", Athens, Greece.
George A
GA
Ioannidis
Institute of Nephrology, Kiev, Ukraine.
Mykola
M
Kolesnyk
Austrian Dialysis and Transplantregistry, Rohr, Austria.
Reinhard
R
Kramar
The Norwegian Renal Registry, Dept. of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Torbjørn
T
Leivestad
Nephrology and Dialysis Unit, Azienda Ospedaliera Fatebenefratelli e Oftalmico, Milano, Italy.
Aurelio
A
Limido
General University Hospital, Department of Medicine - Strahov and Charles University Medical School, Institute of Biophysics and Informatics, Prague, Czech Republic.
Frantisek
F
Lopot
Portuguese Renal Disease Registry, Portuguese Society of Nephrology, Coimbra, Portugal.
Fernando
F
Macario
UNIPAR, Bilbao, Basque Country, Spain.
Ángela
Á
Magaz
Coordinador del Registro Español de Enfermos Renales, Spain.
Eduardo
E
Martín-Escobar
Scottish Renal Registry, Cirrus House, Abbotsinch, Paisley, Scotland, UK.
Wendy
W
Metcalfe
ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Marlies
M
Noordzij
Department of Internal Medicine, Tartu University, Tartu, Estonia.
Mai
M
Ots-Rosenberg
Division of Nephrology, Landspitali, The National University Hospital of Iceland and Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Runolfur
R
Palsson
Servicio de Nefrología, Hospital Universitario Valdecilla, Santander (Cantabria), Spain.
Celestino
C
Piñera
CNR-IBIM Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Renal and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy.
Maurizio
M
Postorino
Department of Internal Medicine, Hospital of Helsingborg, Helsingborg, Sweden.
Karl G
KG
Prutz
Nephrology and Haemodialysis Department, Clinical Center of Montenegro, Podgorica, Montenegro.
Marina
M
Ratkovic
Clinic for Hemodialysis, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Halima
H
Resic
Coordinador Autonómico de Trasplante de Órganos y Tejidos, Canarias, Spain.
Aurelio
A
Rodríguez Hernández
Polish Renal Registry, Department of Nephrology, Transplantology and Internal Disease, Medical University Gdansk, Gdansk, Poland.
Boleslaw
B
Rutkowski
Division of Nephrology, Department of Internal Medicine, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.
Kamil
K
Serdengeçti
Registro de Enfermos Renales de Castilla la Mancha, Spain.
Tomas Sierra
TS
Yebenes
Slovak Medical University, Bratislava, Slovakia.
Viera
V
Spustová
Macedonian Renal Registry, University Clinic of Nephrology, University "Sts. Cyril and Methodius" Skopje, Skopje, Republic of Macedonia.
Olivera
O
Stojceva-Taneva
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow, Russia; Moscow State University of Medicine and Dentistry, Moscow, Russia.
Natalia A
NA
Tomilina
ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Moniek W M
MW
van de Luijtgaarden
ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Karlijn J
KJ
van Stralen
Division of Nephrology, University Clinic, University of Würzburg, Würzburg, Germany.
Christoph
C
Wanner
ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Kitty J
KJ
Jager