Parvovirus B19 Infection Presenting as Pre-B-Cell Acute Lymphoblastic Leukemia: A Transient and Progressive Course in Two Children.
Parvovirus B19 is the causative agent of various forms of hematologic diseases such as aplastic crisis in patients with hemolytic anemia, aplastic anemia, hypoplastic anemia, and idiopathic thrombocytopenic purpura. In addition, parvovirus B19 infection may precede or be associated with acute lymphoblastic leukemia (ALL). The authors present two cases of parvovirus B19 infection and bone marrow infiltration with pre-B-cell lymphoblasts; one patients was diagnosed as having ALL, and the other patient, with neurologic findings, showed total resolution of the blastic morphology and phenotype.
From the *Hematology Unit, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey; and †Neurology Unit, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Sevgi
S
Yetgin
Mualla
M
Çetin
Deniz
D
Aslan
Emel
E
Öyürek
Banu
B
Anlar
Duygu
D
Uçkan