The Disability Rate of 5-Year Post-Stroke and Its Correlation Factors: A National Survey in China.
Few studies on long-term functional outcome have been conducted in post-stroke patients in China. The objective of this study was to conduct a nationwide survey in China to investigate the 5-year prevalence of post-stroke disability and its correlation factors. A total of 893 patients with ischemic stroke were included. Demographic, clinical and neuro-imaging information were collected with standardized instruments that assessed stroke severity, depression, cognitive impairment, stroke recurrence and physical disability. Disability was assessed with the modified Ranking Score (mRS), of which a cutoff score ≥2 indicates disability. Statistical analysis included chi-square tests, two independent samples t-tests, Mann-Whitney U test and multiple logistic regression analysis. The frequency of disability in this study population was 45%. Multivariate analyses revealed that older age, lower education level, previous history of stroke, stroke severity at admission, depression, cognitive impairment at 3 months, and stroke recurrence within 5 years follow up were all significantly associated with post-stroke disability. The disability rate in 5-year post-stroke was high in Chinese patients. Treatment of depression, secondary prevention of stroke and rehabilitation may benefit disabled patients with stroke in China.
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|Department of Neuropsychiatry & Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Yang
Y
Yang
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Yu-Zhi
YZ
Shi
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|Department of Neuropsychiatry & Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Ning
N
Zhang
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Shuo
S
Wang
University of Notre Dame Australia / Marian Centre, Perth, Australia.|School of Psychiatry & Clinical Neurosciences, University of Western Australia, Perth, Australia.
Gabor S
GS
Ungvari
Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia.
Chee H
CH
Ng
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Yi-Long
YL
Wang
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Xing-Quan
XQ
Zhao
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Yong-Jun
YJ
Wang
Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|Department of Neuropsychiatry & Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.|China National Clinical Research Center for Neurological Diseases, Beijing, China.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
Chun-Xue
CX
Wang
Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Yu-Tao
YT
Xiang
D002545:Brain Ischemia / Q000150:complications; D016009:Chi-Square Distribution; D002681:China; D003072:Cognition Disorders / Q000150:complications; D003866:Depressive Disorder / Q000150:complications; D004185:Disability Evaluation; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011446:Prospective Studies; D020127:Recovery of Function / Q000502:physiology; D020521:Stroke / Q000150:complications*; D000071939:Stroke Rehabilitation / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D013997:Time Factors