Acrokeratosis verruciformis of Hopf - Case report.
A 54 year-old woman with a 3-year history of rheumatoid arthritis (RA) consulted us because of weight loss, fever and skin eruption. On physical examination, erythematous plaques with a pseudo-vesicular appearance were seen on the back of both shoulders. Histological examination was consistent with rheumatoid neutrophilic dermatosis (RND). After three days of prednisone treatment, the skin eruption resolved. RND is a rare cutaneous manifestation of seropositive RA, characterized by asymptomatic, symmetrical erythematous plaques with a pseudo-vesicular appearance. Histology characteristically reveals a dense, neutrophilic infiltrate with leucocitoclasis but without other signs of vasculitis. Lesions may resolve spontaneously or with RA treatment. This case illustrates an uncommon skin manifestation of active rheumatoid arthritis.
Instituto Lauro de Souza Lima (ILSL) - Bauru, SP, Brazil.
Tatiana Cristina Pedro Cordeiro de
TC
Andrade
Instituto Lauro de Souza Lima (ILSL) - Bauru, SP, Brazil.
Gardênia Viana da
GV
Silva
Instituto Lauro de Souza Lima (ILSL) - Bauru, SP, Brazil.
Tatiane Meira Pinho
TM
Silva
Instituto Lauro de Souza Lima (ILSL) - Bauru, SP, Brazil.
Ana Cecília Versiani Duarte
AC
Pinto
Instituto Lauro de Souza Lima (ILSL) - Bauru, SP, Brazil.
Adauto José Ferreira
AJ
Nunes
Instituto Lauro de Souza Lima (ILSL) - Bauru, SP, Brazil.
Antônio Carlos Ceribelli
AC
Martelli
D017255:Acitretin / Q000627:therapeutic use; D007644:Darier Disease / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000473:pathology; D010212:Papilloma / Q000473:pathology*
D007641:Keratolytic Agents; D017255:Acitretin