The effects of molecular diffusion in spatially encoded magnetic resonance imaging.
In spatially encoded MRI, the signal is acquired sequentially for different coordinates. In particular for single-scan acquisitions in inhomogeneous fields, spatially encoded methods improve the image quality compared to traditional k-space encoding. Previously, much attention has been paid in order to homogenize T2losses across the sample. In this work, we investigate the effects of diffusion on the image quality in spatially encoded MRI. We show that losses due to diffusion are often not uniform along the spatially encoded dimension, and how to adapt spatially encoded sequences in order to obtain uniformly diffusion-weighted images.
Département de Chimie, École Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolecules (LBM), 24 rue Lhomond, 75005 Paris, France; Sorbonne Universités, UPMC Univ. Paris 06, École Normale Supérieure, CNRS, Laboratoire des Biomolecules (LBM), Paris, France.
Sina
S
Marhabaie
Département de Chimie, École Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolecules (LBM), 24 rue Lhomond, 75005 Paris, France; Sorbonne Universités, UPMC Univ. Paris 06, École Normale Supérieure, CNRS, Laboratoire des Biomolecules (LBM), Paris, France; Institut des Sciences et Ingéniérie Chimiques, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Geoffrey
G
Bodenhausen
Département de Chimie, École Normale Supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Laboratoire des Biomolecules (LBM), 24 rue Lhomond, 75005 Paris, France; Sorbonne Universités, UPMC Univ. Paris 06, École Normale Supérieure, CNRS, Laboratoire des Biomolecules (LBM), Paris, France. Electronic address: Philippe.Pelupessy@ens.fr.
Philippe
P
Pelupessy
Diffusion artifacts; Echo planar imaging; RASER; Single scan MRI; Spatially encoded MRI