[Management of graft failure and erythroblastopenia in patients undergoing allogeneic hematopoietic stem cell transplantation: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Success of allogeneic hematopoietic stem cells transplantation requires both the underlying disease eradication and satisfying reconstitution of hematopoiesis from donor cells. However, reconstitution delays, secondary development or persistence of cytopenia are regularly observed and are potential causes of failure after allogeneic transplantation. These graft dysfunctions should be distinguished from non-engraftment/engraftment failure. Although these situations are relatively common, there is no consensus in the literature for their management. During the workshop of the SFGM-TC, the working group proposed recommendations from an analysis of the literature.
Institut de cancérologie Lucien-Neuwirth, service d'hématologie clinique, 42000 St-Etienne, France. Electronic address: jerome.cornillon@icloire.fr.
Jérôme
J
Cornillon
AP-HP, hôpital St-Louis, service d'hématologie - greffes de moelle, 75010 Paris, France.
Flore
F
Sicre de Fontbrune
Centre hospitalier-universitaire de Caen, institut d'hématologie de Basse-Normandie, 14003 Caen, France.
Sylvain
S
Chantepie
CHU de Lille, université Lille 2, LIRIC Inserm U995, 59000 Lille, France.
Valérie
V
Coiteux
CHU de Lille, université Lille 2, LIRIC Inserm U995, 59000 Lille, France.
Jordan
J
Gauthier
Hôpitaux universitaires de Genève, service d'hématologie, 1205 Genève, Suisse.
Stavroula
S
Masouridi-Levrat
CHU de Nancy, service d'hématologie, unité de transplantation médullaire allogénique, 54500 Nancy, France.
Cécile
C
Pochon
CHRU de Lille, service de médecine interne, unité d'immunologie clinique, 59000 Lille, France.
Louis
L
Terriou
CHU de Lille, université Lille 2, LIRIC Inserm U995, 59000 Lille, France.
Ibrahim
I
Yakoub-Agha
Université Paris 7, hôpital Robert-Debré, service d'hémato-immunologie, 75019 Paris, France.
Jean-Hugues
JH
Dalle
D006801:Humans; D017707:Erythrocyte Transfusion; D004912:Erythrocytes; D005602:France; D006084:Graft Rejection / Q000175:diagnosis / Q000628:therapy; D006402:Hematologic Diseases / Q000175:diagnosis / Q000628:therapy; D006410:Hematopoiesis; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D055031:Primary Graft Dysfunction / Q000175:diagnosis / Q000628:therapy; D012955:Societies, Medical; D014184:Transplantation, Homologous
Allogreffe de cellules souches hématopoïétiques; Bone marrow transplantation; Dysfonction du greffon; Erythroblastopenia; Graft dysfunction; Érythroblastopénie