Hourly peak PM2.5concentration associated with increased cardiovascular mortality in Guangzhou, China.
Hourly peak concentration may capture health effects of ambient fine particulate matter pollution (PM2.5) better than daily averages. We examined the associations of hourly peak concentration of PM2.5with cardiovascular mortality in Guangzhou, China. We obtained daily data on cardiovascular mortality and hourly PM2.5concentrations in Guangzhou from 19 January 2013 through 30 June 2015. Generalized additive models were applied to evaluate the associations with adjustment for potential confounding factors. Significant associations were found between hourly peak concentrations of PM2.5and cardiovascular mortality, particularly from ischemic heart diseases (IHD) and cerebrovascular diseases (CBD). Every 10 μg/m3increment of hourly peak PM2.5at lag 03 day was associated with a 1.15% (95% CI: 0.67%, 1.63%); 1.02% (95% CI: 0.30%, 1.74%) and 1.09% (95% CI: 0.27%, 1.91%) increase in mortalities from total cardiovascular diseases, IHD and CBD, respectively. The effects remained after adjustment for daily mean PM2.5and gaseous air pollutants, though there was a high correlation between PM2.5peak and PM2.5mean (correlation coefficient=0.95). No significant association was observed for acute myocardial infarction (AMI). In addition to daily mean concentration of PM2.5, hourly peak concentration of PM2.5might be one important risk factor of cardiovascular mortality and should be considered as an important air pollution indicator when assessing the possible cardiovascular effects of PM2.5.
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Hualiang
H
Lin
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Tao
T
Liu
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Jianpeng
J
Xiao
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Weilin
W
Zeng
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Lingchuan
L
Guo
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Xing
X
Li
Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Yanjun
Y
Xu
Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Yonghui
Y
Zhang
College for Public Health and Social Justice, Saint Louis University, Saint Louis, Missouri, USA.
Jen Jen
JJ
Chang
College for Public Health and Social Justice, Saint Louis University, Saint Louis, Missouri, USA.
Michael G
MG
Vaughn
College for Public Health and Social Justice, Saint Louis University, Saint Louis, Missouri, USA.
Zhengmin Min
ZM
Qian
Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Wenjun
W
Ma
D000393:Air Pollutants / Q000009:adverse effects*; D000397:Air Pollution / Q000009:adverse effects*; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000401:mortality*; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000401:mortality; D002681:China / Q000453:epidemiology; D004784:Environmental Monitoring; D006801:Humans; D017202:Myocardial Ischemia; D010316:Particle Size; D052638:Particulate Matter / Q000009:adverse effects*; D016012:Poisson Distribution; D012307:Risk Factors
D000393:Air Pollutants; D052638:Particulate Matter