Botulinum Toxin in the Management of Sialorrhoea in Acquired Brain Injury.
Sialorrhoea as a consequence of severe acquired brain injury can significantly negatively impact on quality of life. Medications used in its management have many side effects which can cause problems in the severely disabled. Botulinum toxin is an effective treatment of sialorrhoea in a number of neurological conditions but may also have a role to play in the management of sialorrhoea following severe ABI. We report on 4 cases of sialorrhoea following acquired brain injury causing a variety of problems, whose parotid glands were injected with Botulinum toxin type A (Dysport) 50mu each, under ultrasound guidance. All cases had a clinically and statistically significant reduction in drooling as measured by the teacher drooling scale (p=0.005) and carers Visual Analogue Scale (p=0.012). There were no side effects reported. Botulinum toxin is an effective treatment for sialorrhoea associated with acquired brain injury.
National Rehabilitation Hospital, Rochestown Ave, Dun Laoghaire, Co Dublin.
A
A
Carrol
National Rehabilitation Hospital, Rochestown Ave, Dun Laoghaire, Co Dublin.
B
B
McGlone
D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D001930:Brain Injuries / Q000150:complications*; D006801:Humans; D009422:Nervous System Diseases / Q000188:drug therapy; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D010306:Parotid Gland; D011788:Quality of Life; D012798:Sialorrhea / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A; C542869:abobotulinumtoxinA