68Ga-DOTANOC Focal Pulmonary Activity With No Corresponding CT Abnormality.
A 28-year-old woman with medullary thyroid cancer treated with total thyroidectomy and bilateral central and right lateral neck nodal resection postoperatively had increasing calcitonin and carcinoembryonic antigen values. A Ga-DOTANOC PET/CT study performed showed tracer-avid disease in the neck, mediastinal, and hilar lymph nodes. However, there were 3 tracer-avid foci in the lungs bilaterally, suggestive of lung metastases but with no corresponding abnormalities on low-dose CT. A negative contrast-enhanced CT of the lungs along with clinical and radiological follow-up confirmed that the lung activity was artifactual, demonstrating the possibility of Ga-DOTANOC-avid iatrogenic pulmonary microembolism.
From the *Nuclear Medicine Department, and †Radiology Department Royal Liverpool University Hospital, Liverpool, United Kingdom.
Emmanouil
E
Panagiotidis
Nagabhushan
N
Seshadri
Rashika
R
Fernando
Priya
P
Healey
Sobhan
S
Vinjamuri
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005710:Gallium Radioisotopes / Q000009:adverse effects*; D006801:Humans; D007049:Iatrogenic Disease; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D009942:Organometallic Compounds / Q000009:adverse effects*; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D011655:Pulmonary Embolism / Q000209:etiology*; D014057:Tomography, X-Ray Computed
C504894:68Ga-DOTANOC; D005710:Gallium Radioisotopes; D009942:Organometallic Compounds