NKp46 Is an NK Cell Fungicidal Pattern Recognition Receptor.
Natural killer (NK) cells are an important contributor to innate host defense because of their role in direct microbial recognition and killing. Vitenshtein et al. make an important contribution by demonstrating that NK cells kill Candida glabrata using the NK activating receptor, NKp46, which recognizes the Epa adhesins.
Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada; The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Canada. Electronic address: shusli@ucalgary.ca.
Shu Shun
SS
Li
Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada; The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Canada; Department of Medicine, University of Calgary, Calgary, Canada. Electronic address: cmody@ucalgary.ca.
Christopher H
CH
Mody
D007694:Killer Cells, Natural; D055627:Natural Cytotoxicity Triggering Receptor 1; D051192:Receptors, Pattern Recognition
D055627:Natural Cytotoxicity Triggering Receptor 1; D051192:Receptors, Pattern Recognition
fungi; innate immunity; natural cytotoxic receptors; natural killer cells