A rare presentation of acute heart failure secondary to aggressive uterine leiomyosarcoma metastatic to the myocardium initially diagnosed as hypertrophic obstructive cardiomyopathy.
Uterine sarcoma is the cause of 3-9% of all uterine malignant neoplasms and has a 2-fold higher incidence in black women as compared to white women. Cellular atypia and abundant mitoses (≥10 per 10 high power fields) as seen in this patient are associated with an increased risk for metastases. Metastases to the heart are infrequently reported with a handful of cases in the literature. We present a case of a 51-year-old woman with aggressively metastatic uterine leiomyosarcoma causing acute heart failure 4 months after initial presentation.
Division of General Medicine, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA.
Michael
M
Karass
Division of General Medicine, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA.
Pratik
P
Mondal
Division of Oncology, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA.
Mohammad
M
Alkayem
Division of Cardiology, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA.
Amole
A
Ojo
Division of Cardiology, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA.
Wilbert S
WS
Aronow
Division of Oncology, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA.
Carmelo
C
Puccio
Uterine leiomyosarcoma; heart failure; myocardium