title: Efficacy and Safety of Prophylactic Uterine Artery Embolization in Pregnancy Termination with Placenta Previa.
abstract: OBJECTIVE
  To appraise the efficacy and safety of prophylactic uterine artery embolization in pregnancy termination with placenta previa.
  
  
  METHODS
  A cohort of 54 consecutive patients with placenta previa underwent prophylactic uterine artery embolization before vaginal delivery from February 2012 to March 2015. Vaginal delivery was attempted in all patients. Cesarean section or hysterectomy was introduced when vaginal delivery failed.
  
  
  RESULTS
  Vaginal delivery succeeded in 50 patients (93.6%) and failed in 4 patients (6.4%), thereupon converted to cesarean delivery. No patients resorted to hysterectomy. Six patients (11.1%) underwent blood transfusion. None of clinical characteristics, including maternal age, gestational age, history of abortion, history of cesarean delivery, and volume of vaginal bleeding, was significantly associated with complete placenta previa (P > 0.05). However, patients with complete placenta previa had a significantly lower successful rate of vaginal delivery than did patients without complete placenta previa (81 vs 100%, P = 0.038). The rate of complications was 3.7%. No major complications were observed.
  
  
  CONCLUSIONS
  Uterine artery embolization is an effective and safe technique to assist pregnancy termination with placenta previa, which may lower the risk of cesarean section, hysterectomy, and blood transfusion.
authors.affiliation: Department of Interventional Therapy, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, Anhui, People's Republic of China. mediprg@bjmu.edu.cn.
authors.forename: Renguang
authors.initials: R
authors.lastname: Pei
authors.affiliation: Department of Interventional Therapy, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, Anhui, People's Republic of China.
authors.forename: Guoxiang
authors.initials: G
authors.lastname: Wang
authors.affiliation: Department of Interventional Therapy, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, Anhui, People's Republic of China.
authors.forename: Heping
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Interventional Therapy, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, Anhui, People's Republic of China.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Huang
authors.affiliation: Department of Interventional Therapy, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, Anhui, People's Republic of China.
authors.forename: Xiaoxing
authors.initials: X
authors.lastname: Yan
authors.affiliation: Department of Interventional Therapy, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, Anhui, People's Republic of China.
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Yang
mesh_terms: D000328:Adult; D002585:Cesarean Section; D015331:Cohort Studies; D036861:Delivery, Obstetric / Q000379:methods*; D005260:Female; D006801:Humans; D010923:Placenta Previa / Q000503:physiopathology*; D011247:Pregnancy; D016896:Treatment Outcome; D055988:Uterine Artery; D055357:Uterine Artery Embolization / Q000009:adverse effects* / Q000379:methods*; D014592:Uterine Hemorrhage / Q000517:prevention & control*; D014599:Uterus / Q000098:blood supply
keywords: Placenta previa; Pregnancy termination; Uterine artery embolization