title: A comparison between capsule endoscopy and double balloon enteroscopy using propensity score-matching analysis in patients with previous obscure gastrointestinal bleeding.
abstract: BACKGROUND
  Recently, diagnosis of obscure gastrointestinal bleeding (OGIB) has improved greatly due to introduction of capsule endoscopy (CE) and double balloon enteroscopy (DBE). However, the efficacy of CE over DBE in patients with previous OGIB remains unclear. This study aimed to compare, in terms of diagnostic yield, the efficacy of DBE with that of CE in patients with previous OGIB.
  
  
  METHODS
  We enrolled 223 consecutive patients with previous OGIB who were treated between May 2007 and March 2012. We retrospectively evaluated the respective diagnostic yields of CE and DBE in patients with previous OGIB using propensity score-matching analysis. We compared the diagnostic yield of CE with that of DBE.
  
  
  RESULTS
  The diagnostic yields were 41.9% in DBE group and 11.6% in CE group, respectively (p < .01). On logistic regression analysis, DBE was significantly superior to CE after matching (Odds ratio [OR], 4.25; 95% confidence interval [CI], 1.43-12.6; p < .01), even after adjustment for propensity score (OR, 5.65; 95% CI, 1.56?20.5; p < .01).
  
  
  CONCLUSIONS
  Our results indicate that DBE might be more useful and perhaps safer than CE in achieving a positive diagnosis in patients with previous OGIB.
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kakiya
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Shiba
authors.affiliation: b Department of Gastroenterology , Minami Osaka Hospital , Osaka , Japan.
authors.forename: Junichi
authors.initials: J
authors.lastname: Okamoto
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Kato
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Minamino
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Ominami
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Shusei
authors.initials: S
authors.lastname: Fukunaga
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Nagami
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Sugimori
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tanigawa
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Yamagami
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Toshio
authors.initials: T
authors.lastname: Watanabe
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Kazunari
authors.initials: K
authors.lastname: Tominaga
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Fujiwara
authors.affiliation: a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Arakawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D053704:Capsule Endoscopy / Q000379:methods*; D058582:Double-Balloon Enteroscopy / Q000379:methods*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis*; D006801:Humans; D007564:Japan; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D057216:Propensity Score; D012189:Retrospective Studies
keywords: Capsule endoscopy; double-balloon enteroscopy; previous obscure gastrointestinal bleeding; propensity score-matching analysis