title: [Topical corticosteroids as a therapeutic alternative in linear immunoglobulin A bullous dermatosis in childhood: case report].
abstract: Linear immunoglobulin A dermatosis of childhood is a rare autoimmune disorder. Its etiology remains unknown, although it has been linked to drugs, infections, immunological diseases and lymphoproliferative processes. We report the case of a 6 year old girl who consulted for perioral bullous lesions without other symptoms. Neither treatment with mupirocin nor methylprednisolone therapy achieved remission of cutaneous lesions. Skin biopsy showed a linear immunoglobulin A dermatosis. It was not possible to start treatment with dapsone because of a partial glucose-6-phosphate dehydrogenase deficiency, so topical treatment was maintained with good evolution of lesions. Linear immunoglobulin A dermatosis is a rare disease whose differential diagnosis includes other bullous diseases. Pathology is essential for diagnosis. When treatment with dapsone is not possible, topical corticosteroids may be an alternative, either alone or associated with other treatments.
authors.affiliation: Servicio de Dermatología, Hospital García Orcoyen, Estella, España. fj.gil.saenz@cfnavarra.es.
authors.forename: Francisco José
authors.initials: FJ
authors.lastname: Gil Sáenz
authors.affiliation: Servicio de Dermatología, Hospital García Orcoyen, Estella, España.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Durán Urdániz
authors.affiliation: Servicio de Pediatría, Hospital García Orcoyen, Estella, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Fernández Galar
authors.affiliation: Servicio de Dermatología, Hospital García Orcoyen, Estella, España.
authors.forename: Juan Gimeno
authors.initials: JG
authors.lastname: Ballester
authors.forename: Ana
authors.initials: A
authors.lastname: Herrero Varasa
authors.affiliation: Servicio de Dermatología, Hospital García Orcoyen, Estella, España.
authors.forename: Rosa
authors.initials: R
authors.lastname: Garcés Bordege
mesh_terms: D000287:Administration, Topical; D002648:Child; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D062027:Linear IgA Bullous Dermatosis / Q000188:drug therapy*; D008775:Methylprednisolone / Q000008:administration & dosage*
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone
keywords: Dapsone; Glucose-6-phosphate dehydrogenase; Linear IgA dermatosis; Topical corticosteroids