title: Quantitation of Tumor Angiogenesis In Vitro: An All-In-One Angiogenesis Assay.
abstract: In vitro angiogenesis systems enable the analysis of pro- or anti-angiogenic compounds. Most in vitro models do not reproduce the entire angiogenic cascade, from cell migration and proliferation to tube formation. Here, we describe an all-in-one angiogenesis assay that mimics the entire angiogenic cascade in vitro, rendering this model an ideal tool for the in vitro testing.
authors.affiliation: Faculty of Veterinary Medicine, Institute of Veterinary Anatomy, University of Leipzig, An den Tierkliniken 43, Leipzig, Germany. bahramsoltani@vetmed.uni-leipzig.de.
authors.forename: Mahtab
authors.initials: M
authors.lastname: Bahramsoltani
authors.affiliation: Department of Internal Medicine, HIV Translational Research Unit, Ghent University Hospital, Ghent, Belgium.
authors.forename: Ward
authors.initials: W
authors.lastname: De Spiegelaere
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods*; D002465:Cell Movement; D049109:Cell Proliferation; D042783:Endothelial Cells / Q000166:cytology / Q000473:pathology; D006801:Humans; D055806:Microvessels / Q000166:cytology* / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000473:pathology*
keywords: All-in-one assay; Angiogenic cascade; In vitro angiogenesis; Pro-angiogenic factors; Quantitation; Tumor-induced angiogenesis