title: Analysis of Pulmonary Function Test in Korean Patients With Duchenne Muscular Dystrophy: Comparison of Foreign and Korean Reference Data.
abstract: OBJECTIVE
  To determine the abnormal pulmonary function value in Korean Duchenne muscular dystrophy (DMD) patients, we performed a comparative analysis of the patients' pulmonary function value expressed as % of the overseas reference data and Korean healthy children and adolescent reference data.
  
  
  METHODS
  We performed pulmonary function test (PFT) in a total of 27 DMD patients. We compared the patients' FVC% and FEV1% of the overseas reference data with those of the Korean children and adolescent reference data. Also, we compared the patients' MIP% and MEP% of the prediction equation data with those of the Korean children and adolescent reference data.
  
  
  RESULTS
  Age of the subjects ranged from 8 to 16 years (12.03±2.27 years). The mean maximal expiratory pressure (MEP), maximal inspiratory pressure (MIP), vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and peak cough flow (PCF) were 36.93±9.5 cmH2O, 45.79±17.46 cmH2O, 1.4±0.43 L, 1.45±0.45 L, 1.40±0.41 L, and 206.25±61.21 L/min, respectively. The MIP%, MEP%, and FVC% of the Korean children and adolescent reference data showed statistically significant higher values than those of the prediction equation data.
  
  
  CONCLUSIONS
  We observed a clear numeric difference between Korean DMD patients' pulmonary function value expressed as % of the overseas data and inland data. To perform a precise assessment of respiratory function and to determine appropriate respiratory therapy, pulmonary function values of Korean DMD patients should be interpreted taking into account the inland normal pulmonary function test data.
authors.affiliation: Department of Rehabilitation Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
authors.forename: Tae Sik
authors.identifier: 0000-0001-7847-0561
authors.initials: TS
authors.lastname: Bang
authors.affiliation: Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
authors.forename: Woo Hyuk
authors.identifier: 0000-0001-7108-289X
authors.initials: WH
authors.lastname: Choi
authors.affiliation: Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
authors.forename: Sang Hun
authors.identifier: 0000-0003-4849-5228
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
authors.forename: Je-Sang
authors.identifier: 0000-0001-6617-3113
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Department of Rehabilitation Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
authors.forename: Soo-Yeon
authors.identifier: 0000-0001-5679-0126
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Department of Rehabilitation Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
authors.forename: Myung Jun
authors.identifier: 0000-0003-4010-0383
authors.initials: MJ
authors.lastname: Shin
authors.affiliation: Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Yong Beom
authors.identifier: 0000-0001-5026-1696
authors.initials: YB
authors.lastname: Shin
keywords: Duchenne muscular dystrophy; Reference values; Respiratory function test