title: Novel orbital findings of intracranial hypotension.
abstract: OBJECTIVE
  To determine whether orbital findings on routine brain MRI can be used to differentiate patients with intracranial hypotension from controls.
  
  
  METHODS
  The authors evaluated axial T2-weighted images for the amount of optic nerve sheath CSF and 3D-T1-weighted images for optic nerve angle of sixteen patients with intracranial hypotension and 60 controls.
  
  
  RESULTS
  Patients with intracranial hypotension demonstrated significantly decreased CSF in the optic nerve sheath. Optic nerve angle was higher in the intracranial hypotension group compared to controls.
  
  
  CONCLUSIONS
  Decreased optic nerve sheath CSF and straightened optic nerve angle are significantly more common in the setting of intracranial hypotension.
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University Medical Center, 1364 Clifton Rd NE, BG20, Atlanta, GA 30322, United States. Electronic address: johnfholbrook@gmail.com.
authors.forename: John F
authors.initials: JF
authors.lastname: Holbrook
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University Medical Center, 1364 Clifton Rd NE, BG20, Atlanta, GA 30322, United States.
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Hudgins
authors.affiliation: Departments of Ophthalmology and Neurology, Emory University Medical Center, The Emory Clinic Building B, 1365 Clifton Rd NE, Atlanta, GA 30322, United States.
authors.forename: Beau B
authors.initials: BB
authors.lastname: Bruce
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University Medical Center, 1364 Clifton Rd NE, BG20, Atlanta, GA 30322, United States.
authors.forename: Amit M
authors.initials: AM
authors.lastname: Saindane
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D019585:Intracranial Hypotension / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000000981:diagnostic imaging; D015203:Reproducibility of Results
keywords: CSF hypovolemia; Intracranial hypotension; Optic nerve angle; Optic nerve sheath; Orbit