title: Occurrence of Pseudocowpox virus associated to Bovine viral diarrhea virus-1, Brazilian Amazon.
abstract: In 2011, an outbreak of severe vesicular disease occurred in the state of Pará, Amazon region. Besides proliferative or verrucous lesions, cattle showed atypical clinical signs such as diarrhea and leading to death. The animals were submitted to clinical, pathological and molecular diagnosis, and laboratory tests have confirmed the presence of Pseudocowpox virus (PCPV), a Parapoxvirus genus member, and have also found Bovine viral diarrhea virus-1 (BVDV-1), probably causing persistent infection. The results of molecular diagnostics, followed by sequencing data demonstrated the circulation of both viruses (PCPV and BVDV-1) in an area previously affected by another poxvirus, as Vaccinia virus.The cocirculation between PCPV and BVDV-1 indicates a major concern for animal health because the clinical presentation can be a severe disease. This is the first detection of PCPV in the Brazilian Amazon.
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address: pedroaugustoalves@yahoo.com.br.
authors.forename: Pedro A
authors.initials: PA
authors.lastname: Alves
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Poliana O
authors.initials: PO
authors.lastname: Figueiredo
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Cairo H S
authors.initials: CHS
authors.lastname: de Oliveira
authors.affiliation: Universidade Federal do Pará, Castanhal, Pará, Brazil.
authors.forename: José D
authors.initials: JD
authors.lastname: Barbosa
authors.affiliation: Universidade Federal do Pará, Castanhal, Pará, Brazil.
authors.forename: Danillo H S
authors.initials: DHS
authors.lastname: Lima
authors.affiliation: Universidade Federal do Pará, Castanhal, Pará, Brazil.
authors.forename: Henrique A
authors.initials: HA
authors.lastname: Bomjardim
authors.affiliation: Universidade Federal do Pará, Castanhal, Pará, Brazil.
authors.forename: Natália S
authors.initials: NS
authors.lastname: Silva
authors.affiliation: Universidade Federal do Pará, Castanhal, Pará, Brazil.
authors.forename: Karinny F
authors.initials: KF
authors.lastname: Campos
authors.affiliation: Universidade Federal do Pará, Castanhal, Pará, Brazil.
authors.forename: Carlos Magno C
authors.initials: CMC
authors.lastname: Oliveira
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Edel Figueiredo
authors.initials: EF
authors.lastname: Barbosa-Stancioli
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Jônatas S
authors.initials: JS
authors.lastname: Abrahão
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Erna G
authors.initials: EG
authors.lastname: Kroon
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address: giliane@icb.ufmg.br.
authors.forename: Giliane
authors.initials: G
authors.lastname: de Souza Trindade
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000097:blood / Q000235:genetics; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000821:virology*; D001938:Brazil / Q000453:epidemiology; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology*; D060085:Coinfection / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D003967:Diarrhea; D030241:Diarrhea Virus 1, Bovine Viral / Q000235:genetics; D004196:Disease Outbreaks / Q000662:veterinary*; D010802:Phylogeny; D011213:Poxviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D010285:Pseudocowpox Virus / Q000235:genetics / Q000302:isolation & purification*; D060888:Real-Time Polymerase Chain Reaction; D017422:Sequence Analysis, DNA
chemical_list: D000956:Antigens, Viral