title: Toxicology in Reproductive Endocrinology.
abstract: Fertility relies on a series of time dependent events, which are largely regulated by hormones. Concentration and function of these hormones can be altered by exposure of consumed and environmental toxins. It is of important to consider the dose and timing of toxin exposures in assessing the impact of them on reproductive health, however the utility of laboratory assessment in this regard is not well established. General laboratory assessment of reproduction and infertility includes hormone evaluation (hCG, prolactin, TSH, free thyroxin, FSH, LH and androgens among others) and treatment is via various assisted reproductive technologies. Reduction and abstinence from exposure to toxins is recommended to improve reproductive health.
authors.affiliation: Department of Obstetrics and Gynecology, The C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI 48201, USA. Electronic address: rjeelani@med.wayne.edu.
authors.forename: Roohi
authors.initials: R
authors.lastname: Jeelani
authors.affiliation: Department of Pathology, Wayne State University School of Medicine, 540 East Canfield, Detroit, MI 48201, USA; Consolidated Laboratory Management Systems, 24555 Southfield Road, Southfield, MI 48075, USA.
authors.forename: Martin H
authors.initials: MH
authors.lastname: Bluth
authors.affiliation: Department of Obstetrics and Gynecology, The C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI 48201, USA.
authors.forename: Husam M
authors.initials: HM
authors.lastname: Abu-Soud
mesh_terms: D005298:Fertility / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007246:Infertility / Q000139:chemically induced* / Q000175:diagnosis; D027724:Reproductive Techniques, Assisted; D015813:Substance Abuse Detection / Q000379:methods*
keywords: Alcohol; Drugs; Environmental exposure; Health consequences; Infertility; Reproductive outcomes; Subfertility; Toxicology