title: [Stomal Cancer Recurrency, A Clinic-Pathological Consideration].
abstract: Objectives:Analysis of pre-operative tracheostomy and circumjacent tumour free margins as risk factors in the development of stomal recurrent disease after (pharyngo)laryngectomy.Material and Methods:124 patients after (pharyngo)laryngectomy were analyzed for disease related data and tumour samples were analyzed for tumour free margins. The overall cohort was divided into patients with/withour pre-operative tracheostomy.Results:18 patients suffered from recurrent disease (10 stomal, 8 distant metastases). Advanced T-status, female gender, and sub-/glottic tumour manifestation resulted in a higher rate of prior tracheostomy. Pre-operative tracheostomy did not influence the development of stomal recurrency. R0 resection was achieved in 94% of our patients, with significant reduced tumour free margins in patients with stomal recurrency (p=0.002)Conclusion:Pre-operative tracheostomy did not influence the development of stomal recurrent disease. The clinical identification of ventral soft tissue infiltration should result in extensive surgical concepts.
authors.affiliation: Hals-Nasen-Ohrenklinik und Poliklinik, Technische Universität München, München.
authors.forename: S
authors.initials: S
authors.lastname: Teutsch
authors.affiliation: Hals-Nasen-Ohrenklinik und Poliklinik, Technische Universität München, München.
authors.forename: M
authors.initials: M
authors.lastname: Bas
authors.affiliation: Hals-Nasen-Ohrenklinik und Poliklinik, Technische Universität München, München.
authors.forename: H
authors.initials: H
authors.lastname: Bier
authors.affiliation: Hals-Nasen-Ohrenklinik und Poliklinik, Technische Universität München, München.
authors.forename: A
authors.initials: A
authors.lastname: Knopf
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D000072662:Margins of Excision; D008875:Middle Aged; D037981:Neck Dissection; D009364:Neoplasm Recurrence, Local / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D009959:Oropharyngeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D010611:Pharyngectomy; D011183:Postoperative Complications / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D011300:Preoperative Care; D012189:Retrospective Studies; D012307:Risk Factors; D054047:Surgical Stomas / Q000473:pathology*; D014139:Tracheostomy