title: Chromosome-Based blaOXA-48-Like Variants in Shewanella Species Isolates from Food-Producing Animals, Fish, and the Aquatic Environment.
abstract: Carbapenems are considered last-resort antibiotics in health care. Increasing reports of carbapenemase-producing bacteria in food-producing animals and in the environment indicate the importance of this phenomenon in public health. Surveillance for carbapenemase genes and carbapenemase-producing bacteria in Dutch food-producing animals, environmental freshwater, and imported ornamental fish revealed several chromosome-based blaOXA-48-like variants in Shewanella spp., including two new alleles, blaOXA-514and blaOXA-515Carbapenemase genes were not associated with mobile genetic elements or Enterobacteriaceae.
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands daniela.ceccarelli@wur.nl.
authors.forename: Daniela
authors.initials: D
authors.lastname: Ceccarelli
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Alieda
authors.initials: A
authors.lastname: van Essen-Zandbergen
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Kees T
authors.initials: KT
authors.lastname: Veldman
authors.affiliation: Dutch Food and Consumer Protection Authority, Utrecht, The Netherlands.
authors.forename: Nedzib
authors.initials: N
authors.lastname: Tafro
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Olga
authors.initials: O
authors.lastname: Haenen
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands.|Utrecht University, Faculty of Veterinary Medicine, Utrecht, The Netherlands.
authors.forename: Dik J
authors.initials: DJ
authors.lastname: Mevius
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002645:Chickens / Q000382:microbiology; D002876:Chromosomes, Bacterial; D024881:Drug Resistance, Bacterial / Q000187:drug effects / Q000235:genetics; D005399:Fishes / Q000382:microbiology*; D005516:Food Microbiology; D058751:Livestock / Q000382:microbiology*; D009426:Netherlands; D020592:Shewanella / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D013552:Swine / Q000382:microbiology; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases
keywords: OXA-48; Shewanella; antibiotic resistance; carbapenemase; carbapenems; fish; freshwater; livestock