title: Reference values of cardiac ventricular structure and function by steady-state free-procession MRI at 3.0T in healthy adult chinese volunteers.
abstract: To establish normal reference values of left ventricular (LV) and right ventricular (RV) dimension, volume, mass, and ejection fraction in a Chinese population using cardiac magnetic resonance imaging (MRI).
  
  
  
  A total of 120 (60 males; 60 females; 23-83 years) healthy Han Chinese subjects without cardiovascular disease or risk factors were recruited. They underwent comprehensive MRI examination at 3.0T. LV/RV morphology and function were evaluated by steady-state free-procession (SSFP) sequence. Parameters were analyzed according to a standard postprocessing protocol.
  
  
  
  Significant differences in LV size, mass, volume, and ejection fraction (EF) between sexes were noted (all P < 0.05). After indexing using body surface area (BSA), LV end-diastolic volume (EDV), and LV mass index were greater in males than in females (76.5 vs. 68.7 mL/m, P < 0.001; 52.9 vs. 45.1 g/m, P < 0.001; respectively). LVEF was lower in males than in females (64.6% vs. 67.1%, P = 0.007, respectively). RV volume was higher and RVEF lower in males compared with females (75.3 vs. 62.7 mL/m, P < 0.001; 59.9% vs. 62.6%, P = 0.001, respectively). Age was associated significantly with indices of LV and RV volume in females (left ventricular end-diastolic volume index: r = -0.41 P = 0.001; left ventricular end-systolic volume index: r = -0.37 P = 0.004; left ventricular end-diastolic volume index: r = -0.53 P < 0.001; right ventricular end-systolic volume index: r = -0.43 P < 0.001), but not in males (all P > 0.05).
  
  
  
  These data suggest that sex and age affect ventricular parameters in healthy Han Chinese subjects without cardiovascular disease or risk factors.
  
  
  
  2 Technical Efficacy: Stage 2 J. MAGN. RESON. IMAGING 2017;45:1684-1692.
authors.affiliation: Cardiology Division, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Lei
authors.affiliation: Cardiology Division, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
authors.affiliation: Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
authors.forename: Yuchi
authors.initials: Y
authors.lastname: Han
authors.affiliation: Radiology Department, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Cheng
authors.affiliation: Radiology Department, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Jiayu
authors.initials: J
authors.lastname: Sun
authors.affiliation: Cardiology Division, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Luo
authors.affiliation: Cardiology Division, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Yang
authors.affiliation: Cardiology Division, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Dong
authors.affiliation: Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Key Laboratory for MRI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
authors.forename: Yiochu
authors.initials: Y
authors.lastname: Chung
authors.affiliation: Cardiology Division, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
authors.forename: Yucheng
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology / Q000502:physiology*; D002681:China / Q000453:epidemiology; D005260:Female; D006334:Heart Function Tests / Q000592:standards*; D006352:Heart Ventricles / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000592:standards*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012737:Sex Factors; D013318:Stroke Volume; D016276:Ventricular Function / Q000502:physiology*; D055815:Young Adult
keywords: 3.0T; dimension; mass; normal reference; steady-state free precession; volume