title: Towards the mechanical characterization of abdominal wall by inverse analysis.
abstract: The aim of this study is to characterize the passive mechanical behaviour of abdominal wall in vivo in an animal model using only external cameras and numerical analysis. The main objective lies in defining a methodology that provides in vivo information of a specific patient without altering mechanical properties. It is demonstrated in the mechanical study of abdomen for hernia purposes. Mechanical tests consisted on pneumoperitoneum tests performed on New Zealand rabbits, where inner pressure was varied from 0mmHg to 12mmHg. Changes in the external abdominal surface were recorded and several points were tracked. Based on their coordinates we reconstructed a 3D finite element model of the abdominal wall, considering an incompressible hyperelastic material model defined by two parameters. The spatial distributions of these parameters (shear modulus and non linear parameter) were calculated by inverse analysis, using two different types of regularization: Total Variation Diminishing (TVD) and Tikhonov (H1). After solving the inverse problem, the distribution of the material parameters were obtained along the abdominal surface. Accuracy of the results was evaluated for the last level of pressure. Results revealed a higher value of the shear modulus in a wide stripe along the craneo-caudal direction, associated with the presence of linea alba in conjunction with fascias and rectus abdominis. Non linear parameter distribution was smoother and the location of higher values varied with the regularization type. Both regularizations proved to yield in an accurate predicted displacement field, but H1obtained a smoother material parameter distribution while TVD included some discontinuities. The methodology here presented was able to characterize in vivo the passive non linear mechanical response of the abdominal wall.
authors.affiliation: Aragón Institute of Engineering Research (I3A), Universidad de Zaragoza, Spain. Electronic address: rsimon@unizar.es.
authors.forename: R
authors.initials: R
authors.lastname: Simón-Allué
authors.affiliation: Aragón Institute of Engineering Research (I3A), Universidad de Zaragoza, Spain; Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain.
authors.forename: B
authors.initials: B
authors.lastname: Calvo
authors.affiliation: Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Oberai
authors.affiliation: Mechanical Department, Boston University, Boston, MA, USA.
authors.forename: P E
authors.initials: PE
authors.lastname: Barbone
mesh_terms: D034861:Abdominal Wall / Q000502:physiology*; D000818:Animals; D001696:Biomechanical Phenomena; D004548:Elasticity; D020342:Finite Element Analysis; D011312:Pressure; D011817:Rabbits; D017568:Rectus Abdominis / Q000502:physiology; D013314:Stress, Mechanical
keywords: Abdominal wall; In-vivo tests; Inverse analysis; Mechanical properties; Nonlinear elasticity imaging; Patient specific behavior