title: Characteristics of exogenous carbon monoxide deliveries.
abstract: Carbon monoxide (CO) has long been considered an environmental pollutant and a poison. Exogenous exposure to amounts of CO beyond the physiologic level of the body can result in a protective or adaptive response. However, as a gasotransmitter, endogenous CO is important for multiple physiologic functions. To date, at least seven distinct methods of delivering CO have been utilized in animal and clinical studies. In this mini-review, we summarize the exogenous CO delivery methods and compare their advantages and disadvantages.
authors.affiliation: Department of Navy Aeromedicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, China; Department of Hyperbaric Oxygen, Navy General Hospital, Beijing, China.
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Hu
authors.affiliation: Department of Hyperbaric Oxygen, Navy General Hospital, Beijing, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Sun
authors.affiliation: Department of Navy Aeromedicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, China.
authors.forename: Zhou-Heng
authors.initials: ZH
authors.lastname: Ye
authors.affiliation: Department of Navy Aeromedicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, China.
authors.forename: Xue-Jun
authors.identifier: 0000-0003-2387-5531
authors.initials: XJ
authors.lastname: Sun
keywords: CO-releasing molecules; carbon monoxide; carboxyhemoglobin; delivery methods; exogenous