title: High-capacity hollow porous dummy molecular imprinted polymers using ionic liquid as functional monomer for selective recognition of salicylic acid.
abstract: The existence of strong intramolecular hydrogen bond in salicylic acid (SA) weakens its intermolecular hydrogen bonding with functional monomer, then it is a challenge work to fabricate molecularly imprinted polymers (MIPs) for SA recognition with high capacity and good selectivity. Here, hollow porous dummy MIPs (HPDMIPs) were prepared using benzoic acid (BA) as dummy template, ionic liquid (i.e. 1-vinyl-3-methylimidazolium chloride) as functional monomer, and MCM-48 as sacrificial support. Factors that affected adsorption, such as type of template and porogen, mole ratio of template-functional monomer-cross-linker and type of binding solvent, were optimized in detail. Multiple strong interactions between SA and ionic liquid in HPDMIPs deduced higher binding capacity (29.75mg/g), imprinting factor (5.61) and selectivity than any previously reported MIPs by traditional or surface imprinting technology. The large surface area (543.9m2/g) with hollow porous structure resulted in faster kinetic binding (25min). The equilibrium data fitted well to Freundlich equation and the adsorption process could be described by pseudo-second order model. Finally, HPDMIPs were successfully applied to selectively extract and enrich SA from Actinidia chinensis with a relatively high recovery (84.6-94.5%).
authors.affiliation: School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, PR China. Electronic address: xhy330@126.com.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Xiang
authors.affiliation: College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China; Key Laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Zhangjiajie 427000, PR China.
authors.forename: Mijun
authors.initials: M
authors.lastname: Peng
authors.affiliation: College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China.
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.affiliation: Key Laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Zhangjiajie 427000, PR China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Peng
authors.affiliation: College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, PR China. Electronic address: shuyshi@gmail.com.
authors.forename: Shuyun
authors.initials: S
authors.lastname: Shi
mesh_terms: D029042:Actinidia / Q000737:chemistry; D000327:Adsorption; D052578:Ionic Liquids / Q000737:chemistry*; D007700:Kinetics; D015233:Models, Statistical; D054802:Molecular Imprinting; D011108:Polymers / Q000737:chemistry*; D020156:Salicylic Acid / Q000032:analysis* / Q000302:isolation & purification*
chemical_list: D052578:Ionic Liquids; D011108:Polymers; D020156:Salicylic Acid
keywords: Dummy template; Hollow porous structure; Molecularly imprinted polymers; Salicylic acid; Selective extraction