title: The contribution of Helicobacter pylori to excess gastric cancer in Indigenous and Pacific men: a birth cohort estimate.
abstract: BACKGROUND
  The reasons for higher gastric cancer incidence rates in indigenous populations are debated.
  
  
  METHODS
  We quantify the role of Helicobacter pylori in excess gastric cancer incidence in Māori and Pacific men in New Zealand. Age-standardized gastric cancer rate ratios for 1981-2004 were calculated in Māori and Pacific men compared with European/other men born in 1926-1940 and in 1941-1955. Rate ratios were then compared with those restricted to H. pylori prevalent populations.
  
  
  RESULTS
  H. pylori contributed substantially to excess gastric cancer incidence in Māori men (50%, 61%) and Pacific men (71%, 82%) in both cohorts.
  
  
  CONCLUSIONS
  Policy should focus on reducing the acquisition and prevalence of H. pylori infection in these populations.
authors.affiliation: Department of Public Health, University of Otago, PO Box 7343, Wellington, New Zealand. andrea.teng@otago.ac.nz.
authors.forename: Andrea M
authors.initials: AM
authors.lastname: Teng
authors.affiliation: Department of Public Health, University of Otago, PO Box 7343, Wellington, New Zealand.
authors.forename: Tony
authors.initials: T
authors.lastname: Blakely
authors.affiliation: Department of Public Health, University of Otago, PO Box 7343, Wellington, New Zealand.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Baker
authors.affiliation: Department of Public Health, University of Otago, PO Box 7343, Wellington, New Zealand.
authors.forename: Diana
authors.initials: D
authors.lastname: Sarfati
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D016481:Helicobacter Infections / Q000150:complications / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010139:Pacific Islands / Q000453:epidemiology; D044382:Population Groups; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000382:microbiology*
keywords: Chronic infection; Disparity; Gastric cancer; Inequity; Noncardia cancer