title: Recent advances inEntamoebabiology: RNA interference, drug discovery, and gut microbiome.
abstract: In recent years, substantial progress has been made in understanding the molecular and cell biology of the human parasiteEntamoeba histolytica, an important pathogen with significant global impact. This review outlines some recent advances in theEntamoebafield in the last five years, focusing on areas that have not recently been discussed in detail: (i) molecular mechanisms regulating parasite gene expression, (ii) new efforts at drug discovery using high-throughput drug screens, and (iii) the effect of gut microbiota on amoebiasis.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA.
authors.forename: Pedro
authors.initials: P
authors.lastname: Morgado
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA.
authors.forename: Dipak
authors.initials: D
authors.lastname: Manna
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA.|Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
authors.forename: Upinder
authors.initials: U
authors.lastname: Singh
keywords: Entamoeba; amoebiasis; parasite; protozoa