title: Segmental Surface Referencing during Intraoperative Three-dimensional Image-Guided Spine Navigation: An Early Validation with Comparison to Automated Referencing.
abstract: Study DesignInterventional human cadaver study.ObjectiveIntraoperative three-dimensional (3-D)-guided navigation improves spine instrumentation accuracy. However, image acquisition may need to be repeated with segment hypermobility or distant target from reference frame (RF). The current study evaluates the usefulness of internal metal fiducials (IMFs) as surface references in enhancing registration accuracy and avoiding repeating imaging.MethodsSix fresh-frozen cadaveric human torsos were utilized. Posterior C1-T2 exposure was done, and three IMFs were inserted per level; intraoperative 3-D images were then acquired. Two registration methods were utilized: autoregistration (AR, group 1) and point registration using IMF (IMFR, group 2). Registration accuracy was checked by identifying IMFs in both groups. Pedicle screws inserted into C2, C4, C5, and C7 based on the two registration methods (three cadavers each) with RF on C7 and then on C2.ResultsThe mean registration error was lower with IMFR compared with AR (0.35 ± 0.5 mm versus 2.02 ± 0.85 mm,p= 0.0001). Overall, 34 pedicle screws were inserted (AR, 18; IMFR, 16). Final screw placement was comparable using both techniques (p= 0.58). Lateral screws violations were observed in four IMFR screws (1 to 2 mm) as compared with five in AR group (2 to 3 mm). Reregistration after moving RF to C2 was possible using surface screws in IMFR group, thus avoiding new 3-D image acquisition.ConclusionDuring intraoperative 3-D navigation in spine procedures, surface fiducial registration using IMF provided superior accuracy over automated registration. It allowed repeat registration without repeating radiation during long spine segment instrumentations. More studies are needed to clarify both practical and clinical application of this method.
authors.affiliation: Division of Neurosurgery, Department of Surgery, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Amro F
authors.initials: AF
authors.lastname: Al-Habib
authors.affiliation: Neurospinal Unit, Department of Surgery, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
authors.forename: Salah
authors.initials: S
authors.lastname: Al-Akkad
keywords: O-arm; cervical spine; fiducial markers; pedicle screws; spine instrumentation; spine navigation