title: Determination of 255 pesticides in edible vegetable oils using QuEChERS method and gas chromatography tandem mass spectrometry.
abstract: In this study, a simple and high-throughput method for determination of 255 pesticides in vegetable oils was developed based on QuEChERS sample preparation method combined with gas chromatography-triple quadrupole mass spectrometry. Different clean-up approaches were tested: A, 150 mg PSA + 150 mg C18; B, 250 mg PSA + 250 mg C18; C, 250 mg PSA + 250 mg C18 + 15 mg GCB; D, 250 mg PSA + 250 mg C18 + 50 mg GCB; and E, EMR-LipidTM. Best clean-up capacity was observed for EMR clean-up. The extraction procedures and parameters, including extraction time, solvent/sample ratio, and buffer system, were also thoroughly investigated and optimized. The limits of quantification (LOQ) ranged between 5 and 50 μg kg-1, and for the majority of the pesticides the LOQs were 5 μg kg-1, which were below the regulatory MRLs. Most recoveries at seven spiking levels were in the range of 70-120 % with RSDs <20 % indicating satisfactory accuracy. The coefficient of determination (r2) was >0.99 within the calibration linearity range of 2-500 μg L-1for the majority of the pesticides. This method was proved to be simple, sensitive, and effective, which can be applied for large-scale pesticide screening and quantification in vegetable oils.
authors.affiliation: Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin, 300191, China.
authors.forename: Zeying
authors.initials: Z
authors.lastname: He
authors.affiliation: Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin, 300191, China.
authors.forename: Yuehua
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin, 300191, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.affiliation: Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin, 300191, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Peng
authors.affiliation: Agilent Technologies (China) Company, Ltd., No. 3 Wang Jing Bei Road, Chao Yang District, Beijing, 100102, China.
authors.forename: Wenwen
authors.initials: W
authors.lastname: Wang
authors.affiliation: Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin, 300191, China. xwliu2006@163.com.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Liu
mesh_terms: D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D057230:Limit of Detection; D010575:Pesticides / Q000032:analysis*; D010938:Plant Oils / Q000737:chemistry*; D012015:Reference Standards; D015203:Reproducibility of Results; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry / Q000379:methods
chemical_list: D010575:Pesticides; D010938:Plant Oils
keywords: GC–MS/MS; Pesticide residue; QuEChERS; Vegetable oil