title: Clinical Features and Complications of Scleritis in Chinese Patients.
abstract: OBJECTIVE
  To characterize the clinical features of scleritis in Chinese patients.
  
  
  METHODS
  The history, demographics, ocular findings, auxiliary examination findings, complications, systemic diseases and therapeutic effects were analyzed retrospectively.
  
  
  RESULTS
  The study included 124 male and 169 female patients with scleritis. Anterior and posterior scleritis were, respectively, found in 243 and 42 patients. The other eight patients had both anterior and posterior involvement. The mean age of scleritis onset was 39.4 years. Systemic diseases associated with scleritis mainly included rheumatoid arthritis (RA) (4.4%), ankylosing spondylitis (AS) (3.4%), and tuberculosis (1.7%). Anterior uveitis (23.7%), complicated cataract (16.7%), and intraocular hypertension (12.6%) were common complications of scleritis. Scleritis was controlled in 94.6% of the patients treated with corticosteroids combined with immunosuppressive agents.
  
  
  CONCLUSIONS
  Diffuse anterior scleritis was the most common scleritis entity in China. RA and AS were relatively common diseases associated with scleritis. Corticosteroids combined with immunosuppressive agents effectively controlled the disease.
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Peizeng
authors.initials: P
authors.lastname: Yang
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Zi
authors.initials: Z
authors.lastname: Ye
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Jihong
authors.initials: J
authors.lastname: Tang
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Liping
authors.initials: L
authors.lastname: Du
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Qingyun
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Jian
authors.initials: J
authors.lastname: Qi
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Liang
authors.initials: L
authors.lastname: Liang
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Lili
authors.initials: L
authors.lastname: Wu
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Chaokui
authors.initials: C
authors.lastname: Wang
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Mei
authors.initials: M
authors.lastname: Xu
authors.affiliation: a The First Affiliated Hospital of Chongqing Medical University , Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute , Chongqing , P.R. China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Tian
authors.affiliation: b University Eye Clinic Maastricht , Maastricht , the Netherlands.
authors.forename: Aize
authors.initials: A
authors.lastname: Kijlstra
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000150:complications; D044466:Asian People / Q000208:ethnology; D002648:Child; D002681:China / Q000453:epidemiology; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D009887:Ophthalmoscopy; D012189:Retrospective Studies; D015423:Scleritis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000208:ethnology; D013167:Spondylitis, Ankylosing / Q000150:complications; D014057:Tomography, X-Ray Computed
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents
keywords: Clinical characteristics; retrospective study; scleritis