title: The Impact of Aerobic Exercise on Quality of Life in Women with Breast Cancer: A Randomized Controlled Trial.
abstract: BACKGROUND
  The women with breast cancer experience high rates of morbidity due to different treatments. The objective of this study was to evaluate the role of aerobic exercise in the quality of life (QoL) among women suffering from breast cancer in Hamadan, western Iran.
  
  
  METHODS
  Participants who had consummated the eligibility criteria were randomly assigned in exercise group (n=30) and control group (n=30). Written informed consent was obtained from all participants. The mean age was 42.70 ±9.6 and 43.50 ±8.60 yr old in exercise and control groups, respectively. The quality of life was assessed by two widely used standard questionnaires (EORTC QLQ-C30 and EORTC QLQ-BR23). The exercise group received supervised exercise 2 days per week for 10 weeks. Through two stages (before and after intervention) these groups were evaluated. Analyzing the data was performed by SPSS/20.0, using t-test, chi-squared and ANCOVA. P<0.05 was regarded as significant level.
  
  
  RESULTS
  The global health status QoL, based on EORTC QLQ-C30, developed significantly in the exercise group (48.76±24.96 vs. 81.79±16.34) in comparison with the controls (47.75 ±15.73 vs. 52.88 ±14.51) (P<0.001). The exercise intervention was associated with substantial development in total score of functions and symptoms of QoL using EORTC QLQ-BR23 (P<0.001).
  
  
  CONCLUSIONS
  The statistically and clinically crucial developments were indicated in functions and symptoms of QoL in response to exercise in breast cancer women.
authors.affiliation: Mother & Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Shobeiri
authors.affiliation: Mother & Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Seyedeh Zahra
authors.initials: SZ
authors.lastname: Masoumi
authors.affiliation: Department of Midwifery, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Azita
authors.initials: A
authors.lastname: Nikravesh
authors.affiliation: Department of Ergonomics, School of Public Health, Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran. dr_haidari@yahoo.com.
authors.forename: Rashid
authors.initials: R
authors.lastname: Heidari Moghadam
authors.affiliation: Department of Epidemiology, School of Public Health, Social Determinants of Health Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Manoochehr
authors.initials: M
authors.lastname: Karami
mesh_terms: D000328:Adult; D001943:Breast Neoplasms; D015444:Exercise; D005260:Female; D006304:Health Status; D006801:Humans; D007492:Iran; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires; D017741:Survivors
keywords: Breast Cancer; Exercise; Quality of Life; Women