title: Microvascular invasion in hepatocellular carcinoma: is it predictable with a new, preoperative application of diffusion-weighted imaging?
abstract: OBJECTIVE
  The study aimed to explore the use of MRI in predicting the microvascular invasion (MVI) of hepatocellular carcinoma (HCC).
  
  
  METHODS
  The preoperative MRI and tissues of resected HCC patients were collected. The imaging characteristics that have previously been suggested and the mismatch between diffusion-weighted imaging (DWI) and T2-weighted imaging of regions, which the authors called DWI/T2 mismatch, were analyzed and compared with histopathological references.
  
  
  RESULTS
  A multivariate logistic regression analysis showed that DWI/T2 mismatch was an independent predictor of MVI.
  
  
  CONCLUSIONS
  The DWI/T2 mismatch can be a preoperative predictor of MVI for HCC.
authors.affiliation: Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China.
authors.forename: Chun
authors.initials: C
authors.lastname: Yang
authors.affiliation: Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China.
authors.forename: Heqing
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China.
authors.forename: Ruofan
authors.initials: R
authors.lastname: Sheng
authors.affiliation: Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Ji
authors.affiliation: Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China.
authors.forename: Shengxiang
authors.initials: S
authors.lastname: Rao
authors.affiliation: Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China. Electronic address: zengmengsu@outlook.com.
authors.forename: Mengsu
authors.initials: M
authors.lastname: Zeng
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D055806:Microvessels / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods; D012189:Retrospective Studies
keywords: Diffusion-weighted MRI; Hepatocellular carcinoma; Magnetic resonance imaging; Microvascular invasion