title: A new experimental burn model with an infrared heater.
abstract: BACKGROUND
  This study was undertaken to develop new experimental burn injury model using conventional infrared heaters.
  
  
  METHODS
  21 Sprague-Dawley rats were divided into 3 groups. Portion of dorsal area was exposed to infrared radiation from distance of 50 cm to create burn injury. Length of exposure to heat for Group 1 was 5 minutes; Group 2 was exposed for 7½ minutes, and Group 3 was exposed for 10 minutes. Macroscopic and histopathological evaluations were utilized to demonstrate depth and characteristics of injury.
  
  
  RESULTS
  There was no burn injury in first group. Group 2 developed partial thickness burn, and result was full thickness burn injury in Group 3. In Groups 2 and 3 there was statistically significant difference in dermal collagen denaturation. Dermal injury depth was statistically significantly higher in Group 3 compared to Group 2.
  
  
  CONCLUSIONS
  New experimental burn injury model is described using conventional infrared heaters. Standard variables pertaining to model were defined to produce burn injuries at predictable depth: 10 minutes of exposure from 50 cm distance for full thickness burn, and 7½ minutes of exposure from the same distance for partial thickness injury.
authors.affiliation: Department of Plastic Reconstructive and Aesthetic Surgery, Kasımpaşa Military Hospital, İstanbul-Turkey. drserbulent@yahoo.com.
authors.forename: Serbülent
authors.initials: S
authors.lastname: Güzey
authors.affiliation: Department of Plastic Reconstructive and Aesthetic Surgery, Erzurum Military Hospital, Erzurum-Turkey.
authors.forename: Ahmet Demirhan
authors.initials: AD
authors.lastname: Dal
authors.affiliation: Department of Plastic Reconstructive and Aesthetic Surgery, Koru Hospital, Ankara-Turkey.
authors.forename: İsmail
authors.initials: İ
authors.lastname: Şahin
authors.affiliation: Department of Plastic Reconstructive and Aesthetic Surgery, Medical Park Hospital, İstanbul-Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Nişancı
authors.affiliation: Department of Pathology, Gülhane Military Medical Academy, Ankara-Turkey.
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Yavan
mesh_terms: D000818:Animals; D002056:Burns / Q000473:pathology*; D004195:Disease Models, Animal; D007259:Infrared Rays; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000293:injuries* / Q000473:pathology