title: Giant Intrathoracic Meningocele and Breast Cancer in a Neurofibromatosis Type I Patient.
abstract: Intrathoracic meningoceles are relatively rare entities found in patients with neurofibromatosis type I (NF1). Given that both the BRCA1 and NF-1 genes are located on the same long arm of chromosome 17, one would expect concurrence of neurofibromatosis and breast cancer. However, incidence of such co-disorders is very rare in the literature. Here, the authors report a case of a 50-year-old female patient with NF-1 and concurrent cancer of the left breast, who had a huge bilobulated intrathoracic meningocele with thoracic dystrophic scoliosis, treated surgically via a posterior-only approach for the meningocele and spinal deformity in the same setting.
authors.affiliation: Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.
authors.forename: Hridayesh Pratap
authors.initials: HP
authors.lastname: Malla
authors.affiliation: Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.
authors.forename: Bong Jin
authors.initials: BJ
authors.lastname: Park
authors.affiliation: Department of Neurosurgery, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
authors.forename: Jun Seok
authors.initials: JS
authors.lastname: Koh
authors.affiliation: Department of Neurosurgery, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
authors.forename: Dae Jean
authors.initials: DJ
authors.lastname: Jo
keywords: Breast cancer; Meningocele; Neurofibromatosis