title: Hospital-wide comparison of health care-associated infection among 8 intensive care units: A retrospective analysis for 2010-2015.
abstract: Exploring the distribution of nosocomial pathogens among different categories of intensive care units (ICUs) is critical to improving the management of health care-associated infection (HAI). Despite both single- and multicenter studies, the nature of the variations of HAIs within various ICUs remains inadequately evaluated.
  
  
  
  Data on HAIs at our hospital during the period January 2010-December 2015 were collected from 8 ICUs, namely, respiratory, cardiovascular, neurology, neonatal, hematology, emergency, cardiothoracic surgery, and neurosurgery ICUs, at a tertiary hospital.
  
  
  
  We observed a cumulative HAI incidence of 15.6/1,000 patient-days among 6,254 cases of infection at the hospital, as well as obvious interunit variations in HAI distribution. Acinetobacter baumannii was the leading organism of infection in almost every ICU, especially in emergency, neurosurgery, and neonatal ICUs. The most common pathogens were Pseudomonas aeruginosa in the cardiothoracic surgery, emergency, and neonatal ICUs; Klebsiella pneumoniae and Escherichia coli in the neurosurgery, emergency, neonatal, and neurology ICUs; and Candida albicans in both neurology and emergency ICUs.
  
  
  
  Our findings revealed that A baumannii and P aeruginosa were the most common pathogens associated with invasive operations, whereas K pneumoniae and E coli were the most common pathogens in the medical ICUs.
authors.affiliation: Employee Health, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: DongMei
authors.initials: D
authors.lastname: Yue
authors.affiliation: Nursing Department, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
authors.forename: Caiping
authors.initials: C
authors.lastname: Song
authors.affiliation: Department of Hospital Infection Control, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.affiliation: The Clinical Laboratory of Hospital, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Cholestatic Liver Diseases Center, Digestive Diseases Institute of PLA, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Chai
authors.affiliation: Medical Research Center, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Luo
authors.affiliation: Bureau of Medical Administration, Southwest Hospital, Third Military Medical University, Chongqing, China. Electronic address: wuhao@tmmu.edu.cn.
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000453:epidemiology*; D003428:Cross Infection / Q000453:epidemiology*; D005260:Female; D006748:Hospital Departments; D006801:Humans; D015994:Incidence; D007223:Infant; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000453:epidemiology*; D012189:Retrospective Studies
keywords: Acinetobacter baumannii; Neonatal intensive care unit; Pseudomonas aeruginosa