title: A 63-Year-Old Man With Progressive Visual Symptoms.
abstract: A 63-year-old man presented with a 4-year history of insidious onset and gradual progression of visual symptoms including right homonymous hemianopsia, alexia, and simultanagnosia with preserved memory. Magnetic resonance imaging, perfusion single-photon emission computed tomography, and fluorodeoxyglucose positron emission tomographic scans revealed strikingly asymmetric left parieto-occipital abnormality. Neuropsychological testing was performed. The differential diagnosis, pathologic findings, genetic testing results, and diagnosis are discussed.
authors.affiliation: Sunnybrook Health Sciences Centre, Department of Neurology, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Sara B
authors.initials: SB
authors.lastname: Mitchell
authors.affiliation: Center for Human Genetic Research, Massachusetts General Hospital/Harvard Medical School, Boston.
authors.forename: Diane
authors.initials: D
authors.lastname: Lucente
authors.affiliation: Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston.
authors.forename: Mykol
authors.initials: M
authors.lastname: Larvie
authors.affiliation: Department of Pathology, Massachusetts General Hospital/Harvard Medical School, Boston.
authors.forename: M I
authors.initials: MI
authors.lastname: Cobos
authors.affiliation: Department of Pathology, Massachusetts General Hospital/Harvard Medical School, Boston.
authors.forename: Matthew
authors.initials: M
authors.lastname: Frosch
authors.affiliation: Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston.
authors.forename: Bradford C
authors.initials: BC
authors.lastname: Dickerson
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D018450:Disease Progression; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019636:Neurodegenerative Diseases / Q000150:complications; D015899:Tomography, Emission-Computed, Single-Photon; D014786:Vision Disorders / Q000000981:diagnostic imaging / Q000235:genetics / Q000503:physiopathology*