title: Dimensions of tinnitus-related complaints reported by patients and their significant others: protocol for a systematic review.
abstract: Over 70 million people in Europe and >50 million people in the USA are reported to experience tinnitus (the sensation of noise in the absence of any corresponding sound source). Tinnitus is a multidimensional concept. Individual patients may report different profiles of tinnitus-related symptoms which may each require a tailored management approach and an appropriate measure of therapeutic benefit. This systematic review concerns the patient perspective and has the purpose to find what symptoms are reported by people who experience tinnitus and by their significant others.
  
  
  
  This protocol lays out the methodology to define what dimensions of tinnitus-related symptoms patients and their significant others report as being a problem. Methods are defined according to the Preferred Reporting Items for Systematic reviews and Meta-analyses for Protocols (PRISMA-P) 2015 and data will be collated in a narrative synthesis. Findings will contribute to the eventual establishment of a Core Domain Set for clinical trials of tinnitus.
  
  
  
  No ethical issues are foreseen. Findings will be reported at national and international ENT and audiology conferences and in a peer-reviewed journal.
  
  
  
  CRD42015020629.
authors.affiliation: ENT Department, Hospital Cuf Infante Santo-Nova Medical School, Lisbon, Portugal.
authors.forename: Haúla
authors.initials: H
authors.lastname: Haider
authors.affiliation: Nottingham Hearing Biomedical Research Unit, National Institute for Health Research (NIHR), Nottingham, UK.|Otology and Hearing group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Fackrell
authors.affiliation: Department of Audiovestibular Medicine, Halliwell Health and Children's Centre, Bolton NHS Foundation Trust, Bolton, UK.
authors.forename: Veronica
authors.initials: V
authors.lastname: Kennedy
authors.affiliation: Nottingham Hearing Biomedical Research Unit, National Institute for Health Research (NIHR), Nottingham, UK.|Otology and Hearing group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Hall
mesh_terms: D015897:Comorbidity; D006801:Humans; D011788:Quality of Life; D012107:Research Design; D018454:Spouses / Q000523:psychology*; D000078202:Systematic Reviews as Topic; D014012:Tinnitus / Q000453:epidemiology / Q000523:psychology / Q000628:therapy; D006113:United Kingdom; D014481:United States
keywords: QUALITATIVE RESEARCH; STATISTICS & RESEARCH METHODS