title: Copper-catalyzed cascade annulation between α-bromocarbonyls and biaryl or (Z)-arylvinylacetylenes enabling a direct synthesis of dibenzocycloheptanes and related compounds.
abstract: Copper-catalyzed cascade annulation of γ,δ-unsaturated α-bromocarbonyls with biaryl or (Z)-arylvinylacetylenes is presented, giving an expeditious access to dibenzocycloheptanes and related compounds in moderate to high yields. It provides a novel method for the one-pot synthesis of cycloheptane and cycloheptene-fused polycyclic scaffolds featuring a rare 7-endo-trig radical cyclization.
authors.affiliation: Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P. R. China. gangguo@zjnu.cn.
authors.forename: Danyang
authors.initials: D
authors.lastname: Lu
authors.affiliation: Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P. R. China. gangguo@zjnu.cn.
authors.forename: Yimei
authors.initials: Y
authors.lastname: Wan
authors.affiliation: Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P. R. China. gangguo@zjnu.cn.
authors.forename: Lichun
authors.initials: L
authors.lastname: Kong
authors.affiliation: Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P. R. China. gangguo@zjnu.cn.
authors.forename: Gangguo
authors.initials: G
authors.lastname: Zhu