title: [Evolution of type 2 diabetes and carbohydrate intolerance following bariatric surgery in a Mexican mestizo population].
abstract: BACKGROUND
  Bariatric surgery continues to be the best treatment for weight loss and control of obesity related comorbidities. Gastric bypass and sleeve gastrectomy have demonstrated to be the most effective surgeries, but this has not been established in a Mexican (non-American) population.
  
  
  OBJECTIVE
  To analyse the improvement in type 2 diabetes mellitus and carbohydrate intolerance in obese patients after bariatric surgery.
  
  
  METHODS
  A retrospective analysis was performed on the data collected prospectively between 2013 and 2015 on every obese patient with diabetes and carbohydrate intolerance submitted for bariatric surgery. Analysis was performed at baseline, and at 1, 3, 6, 9 and 12 months, and included metabolic, clinical, lipid, and anthropometrical parameters. A peri-operative and morbidity and mortality analysis was also performed. Remission rates for patients with diabetes were also established.
  
  
  RESULTS
  The analysis included 73 patients, 46 with diabetes and 27 with carbohydrate intolerance. Sixty-two patients were female with a mean age of 42 years. Baseline glucose and glycosylated haemoglobin were 123±34mg/dl and 6.8±1.6%, and at 12 months they were 90.1±8mg/dl and 5.4±0.3%, respectively. Diabetes remission was observed in 68.7% of patients, including 9.3% with partial remission and 21.8% with an improvement. There was also a significant improvement in all metabolic and non-metabolic parameters.
  
  
  CONCLUSIONS
  Bariatric surgery safely improves the metabolic status of patients with diabetes mellitus or carbohydrate intolerance during the first year, inducing high rates of complete remission. It has also shown a significant improvement on blood pressure, lipid, and anthropometric parameters during the first year of follow-up.
authors.affiliation: Clínica Integral de Cirugía para la Obesidad y Enfermedades Metabólicas del Hospital General Tláhuac, Secretaría de Salud del Distrito Federal, Ciudad de México, México.
authors.forename: Eva
authors.initials: E
authors.lastname: Ramírez-Avilés
authors.affiliation: Clínica Integral de Cirugía para la Obesidad y Enfermedades Metabólicas del Hospital General Tláhuac, Secretaría de Salud del Distrito Federal, Ciudad de México, México.
authors.forename: Omar
authors.initials: O
authors.lastname: Espinosa-González
authors.affiliation: Clínica Integral de Cirugía para la Obesidad y Enfermedades Metabólicas del Hospital General Tláhuac, Secretaría de Salud del Distrito Federal, Ciudad de México, México.
authors.forename: Mónica
authors.initials: M
authors.lastname: Amado-Galván
authors.affiliation: Clínica Integral de Cirugía para la Obesidad y Enfermedades Metabólicas del Hospital General Tláhuac, Secretaría de Salud del Distrito Federal, Ciudad de México, México.
authors.forename: Hernán
authors.initials: H
authors.lastname: Maydón-González
authors.affiliation: Clínica Integral de Cirugía para la Obesidad y Enfermedades Metabólicas del Hospital General Tláhuac, Secretaría de Salud del Distrito Federal, Ciudad de México, México.
authors.forename: Elisa
authors.initials: E
authors.lastname: Sepúlveda-Guerrero
authors.affiliation: Clínica Integral de Cirugía para la Obesidad y Enfermedades Metabólicas del Hospital General Tláhuac, Secretaría de Salud del Distrito Federal, Ciudad de México, México. Electronic address: zerrweck@yahoo.com.
authors.forename: Carlos
authors.initials: C
authors.lastname: Zerrweck-López
mesh_terms: D000328:Adult; D050110:Bariatric Surgery; D002239:Carbohydrate Metabolism, Inborn Errors / Q000150:complications / Q000601:surgery*; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008286:Malabsorption Syndromes / Q000150:complications / Q000601:surgery*; D008297:Male; D008800:Mexico; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D055815:Young Adult
keywords: Bariatric surgery; Bypass gástrico; Carbohydrate intolerance; Cirugía bariátrica; Diabetes mellitus tipo 2; Gastric bypass; Intolerancia a los carbohidratos; Manga gástrica; Remisión; Remission; Sleeve gastrectomy; Type 2 diabetes mellitus