title: Severe congenital cyclic neutropenia: A case report.
abstract: Congenital cyclic neutropenia syndrome is a constitutional genetic disorder which is characterized by very low number of neutrophils (neutropenia). Patients suffering from this disorder clinically present with neutropenia at early age, history of recurrent fever, ulcerations in the oral cavity, gingivitis, and other recurrent infections. This paper describes a case report of a child with recurrent mouth ulcers, fever, and later diagnosed with severe congenital cyclic neutropenia. This also emphasizes the importance of identification of rare causes of immunosuppressive conditions in children presenting with recurrent oral ulcers and poor dental hygiene, to prevent long-term complications of oral cavity and also morbidity and mortality secondary to neutropenic sepsis.
authors.affiliation: Department of Paedodontics and Preventive Dentistry, KLE University, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.
authors.forename: Vidyavathi H
authors.initials: VH
authors.lastname: Patil
authors.affiliation: Department of Paedodontics and Preventive Dentistry, KLE University, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.
authors.forename: Shivayogi M
authors.initials: SM
authors.lastname: Hugar
authors.affiliation: Department of Hemato-Oncology, KLE University, Dr. Prabhakar Kore Hospital, Belagavi, Karnataka, India.
authors.forename: Girish
authors.initials: G
authors.lastname: Balikai
authors.affiliation: Department of Paedodontics and Preventive Dentistry, ACPM Dental College, Dhule, Maharashtra, India.
authors.forename: Sudha
authors.initials: S
authors.lastname: Patil
keywords: Congenital neutropenia; elastase gene; oral hygiene; oral ulceration; periodontal breakdown