title: Lifestyle chemistries from phones for individual profiling.
abstract: Imagine a scenario where personal belongings such as pens, keys, phones, or handbags are found at an investigative site. It is often valuable to the investigative team that is trying to trace back the belongings to an individual to understand their personal habits, even when DNA evidence is also available. Here, we develop an approach to translate chemistries recovered from personal objects such as phones into a lifestyle sketch of the owner, using mass spectrometry and informatics approaches. Our results show that phones' chemistries reflect a personalized lifestyle profile. The collective repertoire of molecules found on these objects provides a sketch of the lifestyle of an individual by highlighting the type of hygiene/beauty products the person uses, diet, medical status, and even the location where this person may have been. These findings introduce an additional form of trace evidence from skin-associated lifestyle chemicals found on personal belongings. Such information could help a criminal investigator narrowing down the owner of an object found at a crime scene, such as a suspect or missing person.
authors.affiliation: Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92037; pdorrestein@ucsd.edu abouslimani@ucsd.edu.
authors.forename: Amina
authors.initials: A
authors.lastname: Bouslimani
authors.affiliation: Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92037.
authors.forename: Alexey V
authors.initials: AV
authors.lastname: Melnik
authors.affiliation: Department of Pediatrics, University of California, San Diego, La Jolla, CA 92037.
authors.forename: Zhenjiang
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Department of Pediatrics, University of California, San Diego, La Jolla, CA 92037.
authors.forename: Amnon
authors.initials: A
authors.lastname: Amir
authors.affiliation: Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92037.
authors.forename: Ricardo R
authors.initials: RR
authors.lastname: da Silva
authors.affiliation: Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA 92093.
authors.forename: Mingxun
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA 92093.
authors.forename: Nuno
authors.initials: N
authors.lastname: Bandeira
authors.affiliation: Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92037.|Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.|SCiLS GmbH, 28359 Bremen, Germany.
authors.forename: Theodore
authors.initials: T
authors.lastname: Alexandrov
authors.affiliation: Department of Pediatrics, University of California, San Diego, La Jolla, CA 92037.|Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA 92093.|Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA 92307.
authors.forename: Rob
authors.initials: R
authors.lastname: Knight
authors.affiliation: Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92037; pdorrestein@ucsd.edu abouslimani@ucsd.edu.|Department of Pediatrics, University of California, San Diego, La Jolla, CA 92037.|Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA 92307.|Department of Pharmacology, University of California, San Diego, La Jolla,CA 92037.
authors.forename: Pieter C
authors.initials: PC
authors.lastname: Dorrestein
mesh_terms: D000328:Adult; D040421:Cell Phone; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005554:Forensic Medicine; D006225:Hand; D006801:Humans; D008019:Life Style; D015203:Reproducibility of Results; D012867:Skin / Q000737:chemistry; D053719:Tandem Mass Spectrometry / Q000379:methods*
keywords: lifestyle chemistries; phones; skin; trace evidence