title: Aberrant gamma band cortical sources and functional connectivity in adolescents with psychogenic non-epileptic seizures: A preliminary report.
abstract: Psychogenic non-epileptic seizures (PNES) resemble epileptic seizures, but lack clinically evident abnormal electrical activity in the brain. We aimed to assess resting gamma spectral power, current source distribution and functional connectivity in adolescents with PNES. Interictal, 32 channels electroencephalographic recording of 15 adolescents with PNES was compared with 10 matched healthy controls. Spectral power, current source distribution and lagged linear coherence were assessed. Statistically significant gamma spectral power, cortical sources and connectivity pattern was found in some brain areas. Region specific aberrant gamma activity and its relationship to psychopathology are discussed.
authors.affiliation: KS Mani Center for Cognitive Neurosciences, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India. Electronic address: umesh.yes@hotmail.com.
authors.forename: Shreekantiah
authors.initials: S
authors.lastname: Umesh
authors.affiliation: KS Mani Center for Cognitive Neurosciences, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India. Electronic address: cricsai@gmail.com.
authors.forename: Sai Krishna
authors.initials: SK
authors.lastname: Tikka
authors.affiliation: KS Mani Center for Cognitive Neurosciences, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India. Electronic address: psynishant@gmail.com.
authors.forename: Nishant
authors.initials: N
authors.lastname: Goyal
authors.affiliation: KS Mani Center for Cognitive Neurosciences, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India. Electronic address: vinod_sinhacip@yahoo.co.in.
authors.forename: Vinod Kumar
authors.initials: VK
authors.lastname: Sinha
authors.affiliation: KS Mani Center for Cognitive Neurosciences, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India. Electronic address: sh.nizamie@gmail.com.
authors.forename: Shamshul Haque
authors.initials: SH
authors.lastname: Nizamie
mesh_terms: D000293:Adolescent; D001921:Brain / Q000503:physiopathology; D016022:Case-Control Studies; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D065818:Gamma Rhythm / Q000502:physiology*; D006801:Humans; D008297:Male; D010296:Parietal Lobe / Q000503:physiopathology; D011602:Psychophysiologic Disorders / Q000503:physiopathology*; D012146:Rest / Q000502:physiology; D012640:Seizures / Q000503:physiopathology*; D013702:Temporal Lobe / Q000503:physiopathology
keywords: Adolescents; Gamma oscillations; Psychogenic non-epileptic seizures