title: Maximal oxygen uptake and exercise tolerance are improved in rats with heart failure subjected to low-level laser therapy associated with resistance training.
abstract: Exercise tolerance and maximal oxygen uptake (VO2max) are reduced in heart failure (HF). The influence of combined resistance training (RT) and low-level laser therapy (LLLT) on exercise tolerance and VO2maxin HF has not yet been explored. The aim of this study was to evaluate the influence of combined RT and LLLT on VO2maxand exercise tolerance in rats with HF induced by myocardial infarction (MI). Rats were allocated to sedentary sham (Sed-Sham, n = 12), sedentary heart failure (Sed-HF, n = 9), RT heart failure (RT-HF, n = 7) and RT associated with LLLT heart failure (RT + LLLT-HF, n = 7) groups. After MI or sham surgery, rats underwent a RT and LLLT protocol (applied immediately after RT) for 8 weeks. VO2maxand exercise tolerance were evaluated at the end of protocol. HF rats subjected to LLLT combined with RT showed higher VO2basal(41 %), VO2max(40 %), VO2reserve(39 %), run distance (46 %), time to exhaustion (30 %) and maximal velocity (22 %) compared with HF rats that underwent RT alone. LLLT associated with RT improved oxygen uptake and exercise tolerance compared with RT alone in HF rats.
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.|Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Vítor Scotta
authors.initials: VS
authors.lastname: Hentschke
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Lucas
authors.initials: L
authors.lastname: Capalonga
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.|Centro Universitário Franciscano (UNIFRA), Santa Maria, Rio Grande do Sul, Brazil.
authors.forename: Douglas Dalcin
authors.initials: DD
authors.lastname: Rossato
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Júlia Luíza
authors.initials: JL
authors.lastname: Perini
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.|Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Jadson Pereira
authors.initials: JP
authors.lastname: Alves
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.|Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Giuseppe Potrick
authors.initials: GP
authors.lastname: Stefani
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.|Departamento de Fisioterapia, Universidade do Estado de Santa Catarina (UDESC), Florianópolis, Santa Catarina, Brazil.
authors.forename: Marlus
authors.initials: M
authors.lastname: Karsten
authors.affiliation: Departamento de Farmacociências, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Mauro
authors.initials: M
authors.lastname: Pontes
authors.affiliation: Laboratório de Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, Brazil. pdallago@ufcspa.edu.br.|Departamento de Fisioterapia, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Rua Sarmento Leite, 245, 90050-170, Porto Alegre, RS, Brazil. pdallago@ufcspa.edu.br.
authors.forename: Pedro Dal
authors.initials: PD
authors.lastname: Lago
mesh_terms: D000818:Animals; D001835:Body Weight; D006332:Cardiomegaly / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D017079:Exercise Tolerance; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000401:mortality / Q000503:physiopathology / Q000532:radiotherapy*; D006439:Hemodynamics; D006801:Humans; D008099:Liver / Q000473:pathology; D028022:Low-Level Light Therapy / Q000009:adverse effects; D008168:Lung / Q000473:pathology; D008297:Male; D009203:Myocardial Infarction / Q000503:physiopathology / Q000532:radiotherapy; D010100:Oxygen / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D017208:Rats, Wistar; D055070:Resistance Training
chemical_list: D010100:Oxygen
keywords: Echocardiography; Functional capacity; Maximal exercise test; Myocardial infarction; Phototherapy