title: Progressive and self-limiting neurodegenerative disorders in Africa: a new prominent field of research led by South Africa but without strong health policy.
abstract: BACKGROUND
  Neurodegenerative disorders are involved in mortality and morbidity of every country. A high prevalence is estimated in Africa. Neurodegenerative disorders are defined by a progressive or self-limiting alteration of neurons implied in specific functional and anatomical functions. It encompasses a various range of clinical disorders from self-limiting to progressive. Focus on public health policies and scientific research is needed to understand the mechanisms to reduce this high prevalence. We use bibliometrics and mapping tools to explore the area studies and countries involved in scientific research on neurodegenerative disorders in Africa.
  
  
  METHODS
  We used two databases: Web of Science and Pubmed. We analyzed the journals, most cited articles, authors, publication years, organizations, funding agencies, countries and keywords in Web of Science Core collection database and publication years and Medical Subject Headings in Pubmed database. We mapped the data using VOSviewer.
  
  
  RESULTS
  We accessed 44 articles published between 1975 and 2014 in Web of Science Core collection Database and 669 from Pubmed database. The majority of which were after 2006. The main countries involved in research on neurodegenerative disorders in Africa the USA, the United Kingdom, France and South Africa representing the main network collaboration. Clinical neurology and Genetics hereditary are the main Web of Science categories whereas Neurosciences and Biochemistry and Molecular Biology are the main Web of Science categories for the general search "neurodegenerative disorders" not restrained to Africa. This is confirmed by Medical Subject Headings analysis from Pubmed with one more area study: Treatment.
  
  
  CONCLUSIONS
  Neurodegenerative disorders research is leaded by South Africa with a network involving the USA, the UK, as well as African countries such Zambia. The chief field that emerged was on patient and hereditary as well as treatment. Public health policies were lacking fields in research whereas prevalence is estimated to be important in every country. New 17 sustainable development goals of the United Nations could help in this way.
authors.affiliation: CHU Grenoble Alpes, F-38000, Grenoble, France.
authors.forename: Brice
authors.initials: B
authors.lastname: Poreau
mesh_terms: D000349:Africa; D035843:Biomedical Research / Q000458:organization & administration* / Q000706:statistics & numerical data; D016208:Databases, Factual; D006291:Health Policy; D006801:Humans; D019636:Neurodegenerative Diseases / Q000453:epidemiology / Q000517:prevention & control*; D015995:Prevalence; D011634:Public Health; D013019:South Africa
keywords: Neurodegenerative disorders; morbidity; mortality; strong health policy