title: Mental Health Comorbidity in MS: Depression, Anxiety, and Bipolar Disorder.
abstract: Among individuals with multiple sclerosis (MS), mental health comorbidities play a significant role in contributing to secondary disability and detracting from quality of life. This review examines current evidence surrounding three mental health issues of particular relevance to MS: depression, anxiety, and bipolar disorder. We review what is known of the prevalence, correlates, screening mechanisms, and current treatment of each issue and provide recommendations for future areas of research.
authors.affiliation: Rehabilitation Care Service, VA Puget Sound Health Care System, 1660 S. Columbian Way, Seattle, WA, 98108, USA. Aaron.Turner@va.gov.|Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA. Aaron.Turner@va.gov.
authors.forename: Aaron P
authors.initials: AP
authors.lastname: Turner
authors.affiliation: Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.|Department of Neurology, University of Washington, Seattle, WA, USA.
authors.forename: Kevin N
authors.initials: KN
authors.lastname: Alschuler
authors.affiliation: Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Abbey J
authors.initials: AJ
authors.lastname: Hughes
authors.affiliation: Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Meghan
authors.initials: M
authors.lastname: Beier
authors.affiliation: Rehabilitation Care Service, VA Puget Sound Health Care System, 1660 S. Columbian Way, Seattle, WA, 98108, USA.|Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.|Department of Epidemiology, University of Washington, Seattle, WA, USA.
authors.forename: Jodie K
authors.initials: JK
authors.lastname: Haselkorn
authors.affiliation: Rehabilitation Care Service, VA Puget Sound Health Care System, 1660 S. Columbian Way, Seattle, WA, 98108, USA.
authors.forename: Alicia P
authors.initials: AP
authors.lastname: Sloan
authors.affiliation: Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.
authors.forename: Dawn M
authors.initials: DM
authors.lastname: Ehde
mesh_terms: D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D001714:Bipolar Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D006801:Humans; D008603:Mental Health; D009103:Multiple Sclerosis / Q000453:epidemiology*; D015995:Prevalence; D011788:Quality of Life
keywords: Anxiety; Bipolar disorder; Depression; Multiple sclerosis