title: Minimizing Hazards Associated With Live-Virus Immunotherapeutic Cancer Vaccines.
abstract: Therapeutic cancer vaccines that use attenuated vaccinia viruses as delivery vectors are undergoing clinical trials at dozens of sites internationally. Even in an attenuated form, these live viruses can cause severe illness if they are accidentally transmitted to immunocompromised people, pregnant women, or people with certain skin conditions. Oncology nurses should become familiar with how to manage patients' vaccine injection sites to minimize these risks to patients' close contacts and the community at large. .
authors.affiliation: National Cancer Institute, National Institutes of Health.
authors.forename: Sheri
authors.initials: S
authors.lastname: McMahon
mesh_terms: D019496:Cancer Vaccines / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000009:adverse effects / Q000379:methods; D017758:Infectious Disease Transmission, Patient-to-Professional / Q000517:prevention & control; D008297:Male; D009369:Neoplasms / Q000276:immunology / Q000628:therapy; D016272:Occupational Health; D009859:Oncology Nursing / Q000193:education*; D010353:Patient Education as Topic / Q000379:methods; D061214:Patient Safety; D014613:Vaccines, Attenuated / Q000008:administration & dosage* / Q000009:adverse effects; D014765:Viral Vaccines / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D019496:Cancer Vaccines; D014613:Vaccines, Attenuated; D014765:Viral Vaccines
keywords: injection, risk; restrictions; safety ; vaccine; vaccinia