title: Prophylactic Bilateral Nipple-sparing Mastectomy and a Staged Breast Reconstruction Technique: Preliminary Results.
abstract: More high-risk women with breast cancer are identified using genetic testing at a younger age. These young women often opt for prophylactic surgery. Most patients are reluctant for extra donor-site scars besides infections and necrosis. In order to reduce these risks, a two-stage breast reconstruction technique is used for high-risk women with large or ptotic breasts. We presume that this procedure will reduce the risk of skin envelope and nipple-areola complex (NAC) necrosis to less than 1%. In the first stage, an inferior pedicle reduction is performed to obtain large volume reduction with maximal safety for the NAC. The ptosis, skin excess, and malpositioning of the NAC are corrected safely at this stage. In the second stage, the skin-sparing mastectomy is performed with or without nipple sparing. During this procedure, the areola is never removed. A bilateral breast reconstruction is then performed with an immediate subpectoral prothesis or delayed with the use of a subpectoral tissue expander. In this way, we aim to meet the patient's wish to undergo bilateral risk reducing mastectomy in breasts that need ptosis correction without donor-site scarring. This article describes the procedure and reports the preliminary data.
authors.affiliation: Multidisciplinary Breast Clinic-Unit of Gynecologic Oncology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.; Plastic Surgery Unit, Antwerp University Hospital, Antwerpen, Belgium.
authors.forename: Thierry
authors.initials: T
authors.lastname: Tondu
authors.affiliation: Multidisciplinary Breast Clinic-Unit of Gynecologic Oncology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.; Plastic Surgery Unit, Antwerp University Hospital, Antwerpen, Belgium.
authors.forename: Filip
authors.initials: F
authors.lastname: Thiessen
authors.affiliation: Multidisciplinary Breast Clinic-Unit of Gynecologic Oncology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.; Department of Obstetrics and Gynecology, Antwerp University Hospital, University of Antwerp, Antwerpen, Belgium.
authors.forename: Wiebren A A
authors.initials: WA
authors.lastname: Tjalma
keywords: BRCA; high risk; infection; mastectomy; necrosis; nipple sparing; prophylactic; reconstruction