title: Pustular eruption associated with granulocyte colony-stimulating factor treatment.
abstract: We report a case of localized pustular eruption on the face in a patient with Hodgkin lymphoma treated with granulocyte colony-stimulating factor for the development of chemotherapy-induced neutropenia. The administration of granulocyte colony-stimulating factor and the level of neutrophils were closely associated with disease activity, and negative cultures ruled out the hypothesis of an infective etiology. Because of the role of colony-stimulating factor in mobilization of the neutrophils we considered this phenomenon a skin reaction caused by granulocyte colony-stimulating factor-driven neutrophil accumulation.
authors.affiliation: Unit of Dermatology, University of Padua, Padua, Italy.
authors.forename: Maria B
authors.initials: MB
authors.lastname: Brumana
authors.affiliation: Unit of Dermatology, University of Padua, Padua, Italy.
authors.forename: Irene
authors.initials: I
authors.lastname: Russo
authors.affiliation: Unit of Hematology, University of Padua, Padua, Italy.
authors.forename: Renato
authors.initials: R
authors.lastname: Zambello
authors.affiliation: Unit of Dermatology, University of Padua, Padua, Italy - mauro.alaibac@unipd.it.
authors.forename: Mauro
authors.initials: M
authors.lastname: Alaibac
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage / Q000009:adverse effects*; D006689:Hodgkin Disease / Q000188:drug therapy; D006801:Humans; D009503:Neutropenia / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D016179:Granulocyte Colony-Stimulating Factor