title: Parent reported sleep problems in preschool children with sickle cell anemia and controls in East London.
abstract: Snoring and poor sleep may affect cognition, particularly in young children with chronic conditions. Parents of London preschoolers with sickle cell anemia (SCA; n = 22), matched controls (n = 24), and unselected typically developing (n = 142) preschoolers completed sleep questionnaires. Preschoolers with SCA had significantly more sleep problems when compared to matched controls and the larger population. Snoring occurred at least one to two nights a week for 79% of the SCA group. This is compared with 25% of matched controls and 33% of larger population. Randomized controlled trials to improve sleep in young children with SCA already at-risk for cognitive dysfunction should be considered.
authors.affiliation: School of Psychology, University College Dublin, Dublin, Ireland.|Developmental Neurosciences, UCL Institute of Child Health, London, UK.
authors.forename: Michelle
authors.initials: M
authors.lastname: Downes
authors.affiliation: Developmental Neurosciences, UCL Institute of Child Health, London, UK.
authors.forename: Michelle
authors.initials: M
authors.lastname: de Haan
authors.affiliation: Developmental Neurosciences, UCL Institute of Child Health, London, UK.
authors.forename: Fenella J
authors.initials: FJ
authors.lastname: Kirkham
authors.affiliation: Department of Haematology, Barts Health NHS Trust, Royal London hospital, London, UK.
authors.forename: Paul T
authors.initials: PT
authors.lastname: Telfer
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents; D012893:Sleep Wake Disorders / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology*; D011795:Surveys and Questionnaires
keywords: early intervention; obstructive sleep apnea; sickle cell disease; sleep; sleep disordered breathing; snoring