title: Safety of bailout stenting after paclitaxel-coated balloon angioplasty.
abstract: BACKGROUND
  Bailout stenting after suboptimal paclitaxel-coated balloon (PCB) angioplasty is required in up to 28% of cases. We sought to compare the safety of bailout stenting with drug-eluting stents (DES) compared with the more established combination of PCB with bare metal stents (BMS).
  
  
  METHODS
  We retrospectively evaluated all patients who had stents implanted owing to suboptimal PCB angioplasty results between January 2010 and April 2015. Endpoints analyzed were major adverse cardiac events (MACE) - defined as cardiovascular death, nonfatal myocardial infarction (MI), and target lesion revascularization (TLR) - as well as major and minor bleeding.
  
  
  RESULTS
  Baseline clinical characteristics were comparable with a high proportion of diabetics in both groups (50.0% vs. 45.8%, p = 0.74). BMS and DES sizes were similar (mean diameter 2.72 ± 0.50 mm vs. 2.89 ± 0.56 mm, p = 0.20, length 25.22 ± 13.47 mm vs. 28.08 ± 9.08 mm, p = 0.47). Outcomes were comparable at the end of 1 year (MACE 12.2% vs. 9.5%, p = 1.00, TLR 6.1% vs. 4.8%, p = 1.00, MI 0% vs. 4.8%, p = 0.30). There was no case of stent thrombosis or major bleeding, and the rates of minor bleeding were similar (4.2% vs. 4.8%, p = 1.00).
  
  
  CONCLUSIONS
  Our initial experience using DES instead of BMS as a bailout after suboptimal PCB results shows that the procedure is safe and effective at 1 year.
authors.affiliation: Department of Cardiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, Singapore, Singapore.
authors.forename: K H
authors.initials: KH
authors.lastname: Mok
authors.affiliation: Department of Cardiology, Norwich and Norfolk University Hospital, Norwich, UK.
authors.forename: U
authors.initials: U
authors.lastname: Wickramarachchi
authors.affiliation: Department of Cardiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, Singapore, Singapore. timothy_james_watson@ttsh.com.sg.|Faculty of Medicine and Health Science, University of Auckland, Auckland, New Zealand. timothy_james_watson@ttsh.com.sg.
authors.forename: T
authors.initials: T
authors.lastname: Watson
authors.affiliation: Department of Cardiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, Singapore, Singapore.
authors.forename: H H
authors.initials: HH
authors.lastname: Ho
authors.affiliation: Department of Cardiology, Norwich and Norfolk University Hospital, Norwich, UK.
authors.forename: S
authors.initials: S
authors.lastname: Eccleshall
authors.affiliation: Department of Cardiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, Singapore, Singapore.
authors.forename: P J L
authors.initials: PJL
authors.lastname: Ong
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D003131:Combined Modality Therapy; D023921:Coronary Stenosis / Q000601:surgery*; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage*; D061214:Patient Safety; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000601:surgery; D012086:Reoperation; D012189:Retrospective Studies; D012846:Singapore; D015607:Stents
chemical_list: D008670:Metals; D017239:Paclitaxel
keywords: Balloon angioplasty; Coronary stenosis; Drug-eluting stents; Paclitaxel