title: Management of lateral skull base cancer: United Kingdom National Multidisciplinary Guidelines.
abstract: This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. It provides recommendations on the work up and management of lateral skull base cancer based on the existing evidence base for this rare condition. Recommendations • All patients with more than one of: chronic otalgia, bloody otorrhoea, bleeding, mass, facial swelling or palsy should be biopsied. (R) • Magnetic resonance and computed tomography imaging should be performed. (R) • Patients should undergo audiological assessment. (R) • Carotid angiography is recommended in select patients. (G) • The modified Pittsburg T-staging system is recommended. (G) • The minimum operation for cancer involving the temporal bone is a lateral temporal bone resection. (R) • Facial nerve rehabilitation should be initiated at primary surgery. (G) • Anterolateral thigh free flap is the workhorse flap for lateral skull base defect reconstruction. (G) • For patients undergoing surgery for squamous cell carcinoma, at least a superficial parotidectomy and selective neck dissection should be carried out. (R).
authors.affiliation: Manchester Academic Health Sciences Centre,University of Manchester,Manchester,UK.
authors.forename: J J
authors.initials: JJ
authors.lastname: Homer
authors.affiliation: Department of ENT/Head and Neck Surgery,University Hospital Aintree,Liverpool,UK.
authors.forename: T
authors.initials: T
authors.lastname: Lesser
authors.affiliation: Department of Neuro-otology and Skull Base Surgery,University of Cambridge, Cambridge University Teaching Hospitals NHS Foundation Trust,Cambridge,UK.
authors.forename: D
authors.initials: D
authors.lastname: Moffat
authors.affiliation: Department of Clinical Oncology,Christie Hospital NHS Trust,Manchester,UK.
authors.forename: N
authors.initials: N
authors.lastname: Slevin
authors.affiliation: Department of Plastic and Reconstructive Surgery,Cambridge University Teaching Hospitals NHS Foundation Trust,Cambridge,UK.
authors.forename: R
authors.initials: R
authors.lastname: Price
authors.affiliation: Department of Oral and Maxillofacial Surgery,Manchester Royal Infirmary,Manchester,UK.
authors.forename: T
authors.initials: T
authors.lastname: Blackburn
mesh_terms: D001299:Audiometry / Q000592:standards; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D003131:Combined Modality Therapy / Q000592:standards; D005154:Facial Nerve / Q000473:pathology / Q000601:surgery; D006801:Humans; D033183:Interdisciplinary Communication; D008279:Magnetic Resonance Imaging / Q000592:standards; D037981:Neck Dissection / Q000592:standards; D010166:Palliative Care / Q000592:standards; D010307:Parotid Neoplasms / Q000601:surgery; D011182:Postoperative Care / Q000592:standards; D019292:Skull Base Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000628:therapy; D013701:Temporal Bone / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000592:standards; D006113:United Kingdom