title: Leukocytosis and Leukemia.
abstract: Leukocytosis is among the most common findings on peripheral blood smear. A wide range of causes may mediate this finding, and careful clinical and laboratory evaluation assist in differentiating between benign and malignant causes of increased white blood cell counts. In this article, various nonmalignant causes are explored, including infectious, inflammatory, autoimmune, and allergic. In addition, malignant causes of leukocytosis are discussed, including myeloproliferative disorders, acute leukemia, and chronic leukemia, as well as treatment and monitoring for patients with these diseases.
authors.affiliation: Department of Internal Medicine, Rhode Island Hospital, Brown University, JB 0100, 593 Eddy Street, Providence, RI 02903, USA.
authors.forename: Page
authors.initials: P
authors.lastname: Widick
authors.affiliation: Division of Hematology/Oncology, Rhode Island Hospital, Brown University, 593 Eddy Street, Providence, RI 02903, USA. Electronic address: erics_winer@dfci.harvard.edu.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Winer
mesh_terms: D003937:Diagnosis, Differential; D019468:Disease Management; D006403:Hematologic Tests; D006801:Humans; D007938:Leukemia / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D007964:Leukocytosis / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D011320:Primary Health Care
keywords: Inflammation; Leukemia; Leukocytosis; White blood cell count