title: Biology, distribution and control of Anopheles (Cellia) minimus in the context of malaria transmission in northeastern India.
abstract: Among six dominant mosquito vector species involved in malaria transmission in India, Anopheles minimus is a major species in northeast India and held responsible for focal disease outbreaks characterized by high-rise of Plasmodium falciparum infections and attributable death cases. It has been now genetically characterized that among the three-member species of the Minimus Complex spread in Asia, An. minimus (former species A) is prevalent in India including northeastern states and east-central state of Odisha. It is recorded in all seasons and accounts for perennial transmission evidenced by records of sporozoite infections. This species is highly anthropophilic, and largely endophilic and endophagic, recorded breeding throughout the year in slow flowing seepage water streams. The populations of An. minimus in India are reported to be highly diverse indicating population expansion with obvious implications for judicious application of vector control interventions. Given the rapid ecological changes due to deforestation, population migration and expansion and developmental activities, there is scope for further research on the existence of potential additional sibling species within the An. minimus complex and bionomics studies on a large geographical scale for species sanitation. For control of vector populations, DDT continues to be applied on account of retaining susceptibility status even after decades of residual spraying. Anopheles minimus is a highly adaptive species and requires continuous and sustained efforts for its effective control to check transmission and spread of drug-resistant malaria. Anopheles minimus populations are reportedly diminishing in northeastern India whereas it has staged comeback in east-central State of Odisha after decades of disappearance with its eco-biological characteristics intact. It is the high time to siege the opportunity for strengthening interventions against this species for its population diminution to sub-optimal levels for reducing transmission in achieving malaria elimination by target date of 2030.
authors.affiliation: National Institute of Malaria Research (Field Station), Guwahati, 781022, Assam, India.
authors.forename: Vas
authors.initials: V
authors.lastname: Dev
authors.affiliation: Institut de Recherche pour le Développement FRANCE (IRD), LIPMC, UMR-MD3, Faculté de Pharmacie, F-34093, Montpellier, France. sylvie.manguin@ird.fr.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Manguin
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D005260:Female; D006801:Humans; D007194:India; D007303:Insect Vectors / Q000469:parasitology*; D016778:Malaria, Falciparum / Q000469:parasitology / Q000635:transmission*; D008297:Male; D010963:Plasmodium falciparum / Q000502:physiology*; D012621:Seasons
keywords: Anopheles minimus; Distribution; India; Insecticide resistance; Malaria; Sibling species; Vector bionomics; Vector control