title: [Effect and Significance of BIM on Non-small Cell Lung Cancer].
abstract: B-cell lymphoma 2 interacting mediator of cell death (BIM) plays an important role in the progress of cell apoptosis. The lowering expression level or functional defect of which may have an negative effect on the efficacy of anticancer drugs and the prognosis of postoperative patients with non-small cell lung cancer (NSCLC). This review aims to summarize the structure and function of BIM, as well as the relationship between BIM and the therapeutic efficacy of NSCLC.
authors.affiliation: Department of Medical Oncology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
authors.forename: Jingfang
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Medical Oncology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Xin
mesh_terms: D000818:Animals; D000072224:Bcl-2-Like Protein 11 / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics / Q000378:metabolism* / Q000628:therapy; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000628:therapy
chemical_list: D000072224:Bcl-2-Like Protein 11