title: "Giant cell reparative tumor: An exceptional differential diagnosis for a lytic lesion of the temporal bone".
abstract: BACKGROUND
  Giant cell reparative granuloma is a very rare benign osteolytic lesion. It typically arises in the mandible and rarely involves the skull.
  
  
  METHODS
  A 25-year-old male was admitted in August 2002 for a painless left preauricular mass of several months duration. CT scan revealed an osteolytic extradural lesion located in the temporal bone, with extension to infratemporal fossa. We performed a surgical partial resection of the tumour via a frontotemporal approach. At 36 months after surgery, the lesion continued growth and subsequently we decided to perform a preauricular infratemporal approach. After a ten year-follow-up, the patient remained asymptomatic and a small tumour remnant was visible and stable.
  
  
  CONCLUSIONS
  Giant cell reparative granulomas that originate from the temporal bone are exceptional. There are no typical radiological features of this disease. Diagnosis is confirmed by analysis of the surgical specimen. Tumor growth requires surgical resection.
authors.affiliation: Department of Neurosurgery, CHU d'Angers, 49100 Angers, France. Electronic address: bernardflorian.bf@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Bernard
authors.affiliation: Department of Neurosurgery, hôpital Nord, CHU AP-HM, 13015 Marseille, France. Electronic address: lucas.troude@hotmail.fr.
authors.forename: L
authors.initials: L
authors.lastname: Troude
authors.affiliation: Department of Pathology, CHU AP-HM la Timone, 13015 Marseille, France. Electronic address: Corinne.BOUVIER2@ap-hm.fr.
authors.forename: C
authors.initials: C
authors.lastname: Bouvier
authors.affiliation: Department of Neurosurgery, hôpital Nord, CHU AP-HM, 13015 Marseille, France. Electronic address: proche@ap-hm.fr.
authors.forename: P-H
authors.initials: PH
authors.lastname: Roche
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging* / Q000473:pathology*; D015726:Giant Cells / Q000166:cytology*; D006101:Granuloma, Giant Cell / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D008297:Male; D011859:Radiography / Q000379:methods; D013701:Temporal Bone / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: Giant cell reparative granuloma; Infratemporal fossa; Skull base; Surgery