title: Frontal skull osteoblastoma with aneurysmal bone cyst-like changes associated with trauma during pregnancy: a case report.
abstract: We report the case of a large osteoblastoma arising in the frontal bone of a 20-year-old female. The lesion was first noted after a fall, and grew steadily in size following further head injury during pregnancy. Initial plain radiography demonstrated an area of radiolucency, with subsequent cross-sectional imaging revealing the extent of the lesion. Following successful surgical resection, histological features were suggestive of an aggressive osteoblastoma with aneurysmal bone cyst-like changes. We consider the influence of pregnancy and trauma on osteoblastoma behavior.
authors.affiliation: Victor Horsley Department of Neurosurgery, National Hospital of Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK. s.m.toescu@gmail.com.
authors.forename: Sebastian M
authors.initials: SM
authors.lastname: Toescu
authors.affiliation: Victor Horsley Department of Neurosurgery, National Hospital of Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK.
authors.forename: Andrew F
authors.initials: AF
authors.lastname: Alalade
authors.affiliation: Department of Neurosurgery, Royal London Hospital, Whitechapel Road, London, E1 1BB, UK.
authors.forename: Louise
authors.initials: L
authors.lastname: Steele
authors.affiliation: Department of Neurosurgery, Royal London Hospital, Whitechapel Road, London, E1 1BB, UK.
authors.forename: Deepti
authors.initials: D
authors.lastname: Bhargava
authors.affiliation: Department of Neurosurgery, Royal London Hospital, Whitechapel Road, London, E1 1BB, UK.
authors.forename: Roger
authors.initials: R
authors.lastname: Hunter
mesh_terms: D017824:Bone Cysts, Aneurysmal / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D005260:Female; D005624:Frontal Bone / Q000473:pathology; D006801:Humans; D018215:Osteoblastoma / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D011859:Radiography; D014947:Wounds and Injuries / Q000150:complications; D055815:Young Adult
keywords: Aneurysmal bone cyst; Osteoblastoma; Pregnancy; Trauma