title: Health-Related Quality of Life for Children and Adolescents with Specific Language Impairment: A Cohort Study by a Learning Disabilities Reference Center.
abstract: OBJECTIVE
  To assess the health-related quality of life (HRQOL) of children with specific language impairment (SLI).
  
  
  METHODS
  In a prospective sample at a Learning Disabilities Reference Center, proxy-rated HRQOL (KIDSCREEN-27) was assessed for children with SLI and unaffected children from January 1, 2014 to March 31, 2015. Quality of life predictors for children with SLI were evaluated by recording the length and number of speech therapy and psychotherapy sessions and the specific school organization that the children had participated in. The KIDSCREEN scores of the two groups were compared using nonparametric statistics.
  
  
  RESULTS
  The questionnaires were completed by the parents of 67 children with SLI and 67 unaffected children. For children with SLI, the mean HRQOL scores were significantly lower for physical and psychological well-being, autonomy and parent relation, social support, and school environment compared to the reference group, controlling for age and parental education (β = -6.7 (-12.7;-.7) P = 0.03, β = -4.9 (-9.5;-.3) P = 0.04, β = -8.4 (-14.2;-2.6) P = 0.005, β = -11.6 (-19.5;-3.7) P = 0.004, β = -7.1(-12.4;-1.7) P = 0.010, respectively). Multivariate analyses in the group of children with SLI found that children who had undergone psychotherapy sessions or who had been enrolled in specific schooling programs had reduced HRQOL scores in social support and school environment and that children who were in a special class had higher scores in physical well-being.
  
  
  CONCLUSIONS
  Children with SLI had significantly lower HRQOL scores as compared to unaffected children. Measurement of HRQOL could serve as one of the strategies employed throughout the follow-up of these individuals to provide them with the most appropriate and comprehensive care possible.
authors.affiliation: Department of Pediatrics, University Hospital Nantes, Nantes, France.
authors.forename: Gaëlle
authors.initials: G
authors.lastname: Hubert-Dibon
authors.affiliation: Department of Pediatrics, University Hospital Nantes, Nantes, France.|Learning Disabilities Reference Center, University Hospital Nantes, Nantes, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Bru
authors.affiliation: Department of Pediatrics, University Hospital Nantes, Nantes, France.
authors.forename: Christèle
authors.initials: C
authors.lastname: Gras Le Guen
authors.affiliation: Department of Pediatrics, University Hospital Nantes, Nantes, France.
authors.forename: Elise
authors.initials: E
authors.lastname: Launay
authors.affiliation: Learning Disabilities Reference Center, University Hospital Nantes, Nantes, France.|Psychology Laboratory of Pays de la Loire, Angers University, Angers, France.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Roy
mesh_terms: D000293:Adolescent; D000367:Age Factors; D016022:Case-Control Studies; D002648:Child; D015331:Cohort Studies; D003710:Demography; D006262:Health; D006801:Humans; D007806:Language Disorders / Q000150:complications* / Q000453:epidemiology* / Q000534:rehabilitation; D007859:Learning Disabilities / Q000150:complications* / Q000453:epidemiology* / Q000534:rehabilitation; D015999:Multivariate Analysis; D011788:Quality of Life; D012017:Referral and Consultation