title: Statin protects the heart against ischemia-reperfusion injury via inhibition of the NLRP3 inflammasome.
authors.affiliation: Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
authors.forename: Si-Yang
authors.initials: SY
authors.lastname: Yu
authors.affiliation: Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Tang
authors.affiliation: Department of Histology and Embryology, Guilin Medical University, Guilin, Guangxi 541000, China.
authors.forename: Guo-Jun
authors.initials: GJ
authors.lastname: Zhao
authors.affiliation: Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. Electronic address: zhoush_xy2nd@sina.com.
authors.forename: Sheng-Hua
authors.initials: SH
authors.lastname: Zhou
mesh_terms: D000818:Animals; D002316:Cardiotonic Agents / Q000378:metabolism / Q000627:therapeutic use; D004195:Disease Models, Animal; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000378:metabolism / Q000627:therapeutic use*; D058847:Inflammasomes / Q000378:metabolism*; D051379:Mice; D015428:Myocardial Reperfusion Injury / Q000378:metabolism / Q000517:prevention & control; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein / Q000037:antagonists & inhibitors*
chemical_list: D002316:Cardiotonic Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D058847:Inflammasomes; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein
keywords: Myocardial ischemia-reperfusion injury; NLRP3 inflammasome; Statin