title: Sex/gender influences on the nervous system: Basic steps toward clinical progress.
abstract: A Commentary highlighting the progress that sex-based data and research have made in neuroscience and the complexities that research has revealed thus far. Basic and preclinical neuroscientific research that considers sex as a biological variable will continue to build on the foundation of knowledge that has been started by multiple predecessors. The expansion of knowledge in preclinical neuroscience that integrates the study of both sexes will have a significant role in informing clinical trial design. We applaud the efforts of the editors and authors who have contributed to this issue. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.
authors.affiliation: Office of Research on Women's Health (ORWH), Office of the Director, National Institutes of Health, Bethesda, Maryland.
authors.forename: Claudette Elise
authors.initials: CE
authors.lastname: Brooks
authors.affiliation: Office of Research on Women's Health (ORWH), Office of the Director, National Institutes of Health, Bethesda, Maryland.
authors.forename: Janine Austin
authors.initials: JA
authors.lastname: Clayton
mesh_terms: D000818:Animals; D006801:Humans; D009420:Nervous System; D009488:Neurosciences; D012727:Sex Characteristics
keywords: biological variable; preclinical research; reproducibility; sex-based data; women's health