title: EfficientO-Acylation of Alcohols and Phenol Using Cp2TiCl as a Reaction Promoter.
abstract: A method has been developed for the conversion of primary, secondary, and tertiary alcohols, and phenol, into the corresponding esters at room temperature. The method uses a titanium(III) species generated from a substoichiometric amount of titanocene dichloride together with manganese(0) as a reductant, as well as methylene diiodide. It involves a transesterification from an ethyl ester, or a reaction with an acyl chloride. A radical mechanism is proposed for these transformations.
authors.affiliation: Departamento de Química Orgánica University of Cádiz Facultad de Ciencias Polígono Río San Pedro s/n 11510 Puerto Real Cádiz Spain.
authors.forename: María Jesús
authors.identifier: 0000-0002-8816-3095
authors.initials: MJ
authors.lastname: Durán-Peña
authors.affiliation: Departamento de Química Orgánica University of Cádiz Facultad de Ciencias Polígono Río San Pedro s/n 11510 Puerto Real Cádiz Spain.
authors.forename: José Manuel
authors.identifier: 0000-0002-2312-612X
authors.initials: JM
authors.lastname: Botubol-Ares
authors.affiliation: Department of Organic Chemistry University of Sussex BN1 9QJ Brighton Sussex United Kingdom.
authors.forename: James R
authors.identifier: 0000-0003-2985-2920
authors.initials: JR
authors.lastname: Hanson
authors.affiliation: Departamento de Química Orgánica University of Cádiz Facultad de Ciencias Polígono Río San Pedro s/n 11510 Puerto Real Cádiz Spain.
authors.forename: Rosario
authors.identifier: 0000-0003-1887-4796
authors.initials: R
authors.lastname: Hernández-Galán
authors.affiliation: Departamento de Química Orgánica University of Cádiz Facultad de Ciencias Polígono Río San Pedro s/n 11510 Puerto Real Cádiz Spain.
authors.forename: Isidro G
authors.identifier: 0000-0002-8612-0593
authors.initials: IG
authors.lastname: Collado
keywords: Acylation; Esters; Halohydrins; Radical reactions; Titanium