title: Cross-sectional study on case fatality rate due to hantavirus infection in Goiás State, Brazil, 2007-2013.
abstract: to describe the epidemiological and clinical profile of hantavirus infection and to analyze factors associated with case-fatality in Goiás, Brazil.
  
  
  
  this was a cross-sectional study on case fatality due to hantavirus infection from 2007 to 2013 using data from the Notifiable Diseases Information System (SINAN) for Goiás State. Logistic regression analysis was performed to estimate odds ratios (OR) with 95% confidence intervals (95%CI).
  
  
  
  1,171 suspected cases were reported, of which 73 (6.2%) were confirmed. Among the confirmed cases, greater frequency was found among males (n=50), fever was the most common symptom (n=70), and there was a high proportion of hospitalization (n=68). The case-fatality rate was 57.5% . The following factors were associated with death: acute respiratory failure (ARF) (OR=3.6; 95%CI 1.2;10.6), hemoconcentration (OR=3.3; 95%CI 1.1;7.9) and not using a mechanical ventilator (OR=3.4; 95%CI 1.3;9.1). After adjustment, the ARF was still associated with death (OR=3.4; 95%CI 1.0;11.6).
  
  
  
  the case-fatality rate was high, primarily associated with respiratory failure.
authors.affiliation: Universidade Federal de Goiás, Instituto de Ciências da Saúde, Jataí-GO, Brasil.
authors.forename: Hélio Ranes de
authors.initials: HR
authors.lastname: Menezes
authors.affiliation: Universidade Federal de Goiás, Instituto de Ciências da Saúde, Jataí-GO, Brasil.
authors.forename: Marcos Lázaro
authors.initials: ML
authors.lastname: Moreli
authors.affiliation: Universidade Federal de Goiás, Faculdade de Enfermagem, Goiânia-GO, Brasil.
authors.forename: Ana Luiza Lima
authors.initials: AL
authors.lastname: Sousa
authors.affiliation: Universidade Federal de Goiás, Instituto de Ciências da Saúde, Jataí-GO, Brasil.
authors.forename: Vivaldo Gomes da
authors.initials: VG
authors.lastname: Costa
mesh_terms: D001938:Brazil / Q000453:epidemiology; D002423:Cause of Death; D003430:Cross-Sectional Studies; D005260:Female; D005334:Fever / Q000209:etiology; D018778:Hantavirus Infections / Q000150:complications / Q000401:mortality*; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends; D017678:Sex Distribution