title: An open prospective single cohort multicenter study evaluating the novel, tapered, conical connection implants supporting single crowns in the anterior and premolar maxilla: interim 1-year results.
abstract: OBJECTIVE
  The aim of this multicenter prospective clinical study was to evaluate anodized tapered implants with a conical connection and integrated platform shifting placed in the anterior and premolar maxilla.
  
  
  METHODS
  The study enrolled patients requiring single-tooth restorations in healed sites of maxillary anterior and premolar teeth. All implants were immediately temporized. Clinical and radiographic evaluations were conducted at implant insertion, 6 months, and 1 year. Outcome measures included bone remodeling, cumulative survival rate (CSR), success rate, soft-tissue health and esthetics, and patient satisfaction. Bone remodeling and pink esthetic score were analyzed using Wilcoxon signed-rank tests. CSR was calculated using life table analysis. Other soft-tissue outcomes were analyzed using sign tests.
  
  
  RESULTS
  Out of 97 enrolled patients (102 implants), 87 patients (91 implants) completed the 1-year visit. Marginal bone remodeling was -0.85 ± 1.36 mm. After the expected initial bone loss, a mean bone gain of 0.11 ± 1.05 mm was observed between 6 months and 1 year. The CSR was 99.0%, and the cumulative success rate was 97.0%. Partial or full papilla was observed at 30.8% of sites at baseline, 87.2% at 6 months, and 90.5% at 1 year. Soft-tissue response, esthetics, and patient satisfaction all improved during the study period.
  
  
  CONCLUSIONS
  Bone gain was observed following the expected initial bone loss, and soft-tissue outcomes improved suggesting favorable tissue response using anodized tapered conical connection implants.
  
  
  CONCLUSIONS
  Rapid stabilization of bone remodeling and robust papilla regeneration indicate favorable tissue healing promoted by the conical connection, platform-shift design.
  
  
  BACKGROUND
  clinicaltrials.gov NCT02175550.
authors.affiliation: Bernhard Gottlieb University Clinic of Dentistry, Sensengasse 2a, 1090, Vienna, Austria.
authors.forename: Alexander
authors.initials: A
authors.lastname: Fügl
authors.affiliation: Bernhard Gottlieb University Clinic of Dentistry, Sensengasse 2a, 1090, Vienna, Austria. werner.zechner@meduniwien.ac.at.
authors.forename: Werner
authors.initials: W
authors.lastname: Zechner
authors.affiliation: University of Rome Tor Vergata, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Pozzi
authors.affiliation: University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Guido
authors.initials: G
authors.lastname: Heydecke
authors.affiliation: University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Christine
authors.initials: C
authors.lastname: Mirzakhanian
authors.affiliation: University Medical Center of Johannes Gutenberg University Mainz, Mainz, Germany.
authors.forename: Nikolaus
authors.initials: N
authors.lastname: Behneke
authors.affiliation: University Medical Center of Johannes Gutenberg University Mainz, Mainz, Germany.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Behneke
authors.affiliation: University Associates in Dentistry, Chicago, USA.
authors.forename: Russell A
authors.initials: RA
authors.lastname: Baer
authors.affiliation: Private Practice, Lindau, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Nölken
authors.affiliation: Private Practice, New York, USA.
authors.forename: Edward
authors.initials: E
authors.lastname: Gottesman
authors.affiliation: University of Belgrade, Belgrade, Serbia.
authors.forename: Snjezana
authors.initials: S
authors.lastname: Colic
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016723:Bone Remodeling / Q000502:physiology*; D003442:Crowns; D019250:Dental Implants, Single-Tooth; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D004955:Esthetics, Dental; D005260:Female; D006801:Humans; D057893:Immediate Dental Implant Loading; D015993:Life Tables; D008297:Male; D008437:Maxilla / Q000601:surgery; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D016896:Treatment Outcome
keywords: Anterior maxilla; Conical connection; Immediate temporization; Platform shifting