title: Metastatic trichilemmal carcinoma in a patient with breast cancer.
abstract: Trichilemmal carcinoma (TC) is described as a very rare cancer of the skin adnexa.1 2Ninety per cent of the lesions present on the scalp. Prognostic factors in TC are limited to lymph node status and surgical margins, with no statistical significance observed for age or gender of the patient, size of tumour or locoregional recurrence. We present a 46-year-old black patient who developed TC during treatment for breast cancer. Postoperative histology of the scalp lesion excision confirmed no involved margins. At the three monthly appointment, the patient was reviewed and multiple, new scalp lesions were noted. A CT scan of the head, neck found multiple lesions on the scalp, limited to the soft tissue, not involving the outer table of the skull. There was bilateral invasion of the parotid glands. To the best of our knowledge, no syndromes or associations between breast cancer and adnexal skin tumours exist.
authors.affiliation: Department of Plastic and Reconstructive Surgery, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: Chrysis
authors.identifier: http://orcid.org/0000-0002-3438-508X
authors.initials: C
authors.lastname: Sofianos
authors.affiliation: Department of Plastic and Reconstructive Surgery, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: Nkhensani Y
authors.initials: NY
authors.lastname: Chauke
authors.affiliation: Department of Plastic and Reconstructive Surgery, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Grubnik
mesh_terms: D001943:Breast Neoplasms / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018294:Neoplasms, Adnexal and Skin Appendage / Q000473:pathology*; D012535:Scalp