title: A Literature Review of Senile Pruritus: From Diagnosis to Treatment.
abstract: Pruritus occurs frequently in the elderly population, but it has not been fully defined and its precise prevalence is unknown. Putative causes of pruritus are numerous and patients' quality of life can be greatly reduced. In the absence of any specific cause, a diagnosis of senile pruritus is proposed, suggesting that itch is secondary to ageing. However, the relationship of pruritus with skin ageing and/or neuronal ageing and/or immune ageing is poorly understood. Many treatments have been reported, but are poorly effective. This paper reviews the literature on senile pruritus, in order to improve understanding of this condition and to enable improved diagnosis and treatment.
authors.affiliation: Department of Dermatology, University Hospital of Brest, FR-29200 Brest, France.
authors.forename: Caroline-Jade
authors.initials: CJ
authors.lastname: Clerc
authors.forename: Laurent
authors.initials: L
authors.lastname: Misery
mesh_terms: D017668:Age of Onset; D000368:Aged; D000375:Aging / Q000523:psychology; D015577:Geriatric Assessment; D006801:Humans; D011237:Predictive Value of Tests; D015995:Prevalence; D011537:Pruritus / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D012307:Risk Factors; D016896:Treatment Outcome