title: Cholesterol: An Achilles' Heel for Glioblastoma?
abstract: In this issue of Cancer Cell, Villa et al. report that survival of glioblastoma cells is dependent on uptake of cholesterol. A synthetic agonist of the Liver X receptor depleted cholesterol in GBM cells, slowing growth of GBM xenografts.
authors.affiliation: Departments of Neurology, Pediatrics, and Neurosurgery, Brain Tumor Research Center, and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
authors.forename: Zhenyi
authors.initials: Z
authors.lastname: An
authors.affiliation: Departments of Neurology, Pediatrics, and Neurosurgery, Brain Tumor Research Center, and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: waweiss@gmail.com.
authors.forename: William A
authors.initials: WA
authors.lastname: Weiss
mesh_terms: D002784:Cholesterol; D005909:Glioblastoma; D006801:Humans
chemical_list: D002784:Cholesterol