title: A Destabilized Case of Stable Effort Angina Pectoris Induced by Low-dose Adenosine Triphosphate.
abstract: A 79-year-old man was diagnosed with sudden deafness. He had previously experienced a suspected episode of angina pectoris. At a local hospital, after 500 mg of hydrocortisone and 80 mg adenosine triphosphate (ATP) were administered, he became aware of chest discomfort. An electrocardiogram revealed serious ST-segment depressions. He was diagnosed with a non-ST elevated myocardial infarction (NSTEMI). Emergency coronary angiography revealed triple vessel disease, and the lesion was successfully stented. The mechanisms whereby the stable effort angina pectoris destabilized in this case were thought to include a reduction of the local blood flow because of an ATP product and probable thrombus formation in response to the administered steroids.
authors.affiliation: Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Sueta
authors.forename: Sunao
authors.initials: S
authors.lastname: Kojima
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Izumiya
authors.forename: Megumi
authors.initials: M
authors.lastname: Yamamuro
authors.forename: Koichi
authors.initials: K
authors.lastname: Kaikita
authors.forename: Seiji
authors.initials: S
authors.lastname: Hokimoto
authors.forename: Hisao
authors.initials: H
authors.lastname: Ogawa
mesh_terms: D000255:Adenosine Triphosphate / Q000008:administration & dosage / Q000009:adverse effects*; D000368:Aged; D060050:Angina, Stable / Q000188:drug therapy*; D000789:Angina, Unstable / Q000139:chemically induced*; D017023:Coronary Angiography; D004562:Electrocardiography; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000601:surgery; D009204:Myocardial Revascularization; D015607:Stents
chemical_list: D000255:Adenosine Triphosphate; D006854:Hydrocortisone