title: Development of the maxillary sinus in infants and children.
abstract: OBJECTIVE
  To examine the age related volume change of the maxillary sinus in children by measuring the change of the height, weight, and depth using computed tomography (CT).
  
  
  METHODS
  Children <18 years of age who underwent a CT Scan of the sinuses for reasons other than sinus related issues were included in the study.
  
  
  RESULTS
  139 patients were included (68 females and 71 Males) and the mean age of the patients was 9.6 ± 5.4 years. The cohort was divided into three groups based on their ages - Age <6 years (n = 45), age between 6 and 12 years (n = 44) and age > 12 years (n = 50). Patients in each age group demonstrated an increase in their Maxillary sinus height (p<0.001). Patients < 6years of age and between 6 and 12 years of age had a significant increase in their maxillary sinus width and depth (p < 0.001). The maxillary sinus width, depth and volume did not increase significantly after the age of 12 years in these patients.
  
  
  CONCLUSIONS
  We demonstrated periods of significant size increase of the maxillary sinuses as determined by different dimensions in children at various ages. The height of the maxillary sinus has steady growth from birth to at least the age of 18 years. The width and depth increase up to 12 years of age.
authors.affiliation: Department of Surgery, Division of Otolaryngology Head & Neck Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, USA; Department of Otolaryngology Head & Neck Surgery, Northwestern University Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address: BBhushan@luriechildrens.org.
authors.forename: Bharat
authors.initials: B
authors.lastname: Bhushan
authors.affiliation: Biostatistics Research Core, Stanley Manne Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, USA.
authors.forename: Karen
authors.initials: K
authors.lastname: Rychlik
authors.affiliation: Department of Surgery, Division of Otolaryngology Head & Neck Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, USA; Department of Otolaryngology Head & Neck Surgery, Northwestern University Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
authors.forename: James W
authors.initials: JW
authors.lastname: Schroeder
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging* / Q000254:growth & development*; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: Children; Development; Infant sinus; Maxillary sinus; Sinus development