title: Irreversible electroporation for locally advanced pancreatic cancer.
abstract: Pancreatic adenocarcinoma is one of the solid cancers associated with the poorest prognosis; the only curative treatment remains surgical resection but in most cases, this treatment is not possible because of distant metastasis or local extension. Irreversible electroporation is a new tumor ablation technique, which provides cellular apoptosis without any thermal coagulation effect. This technique helps preserve the ducts, vessels or nerves located in the treatment area. This article reviews the current knowledge regarding the use of electroporation for the treatment of pancreatic adenocarcinoma.
authors.affiliation: Department of Imaging, University Hospital of Poitiers, rue de la Milétrie, 86000 Poitiers, France. Electronic address: jean-pierre.tasu@chu-poitiers.fr.
authors.forename: J-P
authors.initials: JP
authors.lastname: Tasu
authors.affiliation: Department of Imaging, University Hospital of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: G
authors.initials: G
authors.lastname: Vesselle
authors.affiliation: Department of Imaging, University Hospital of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: G
authors.initials: G
authors.lastname: Herpe
authors.affiliation: Laboratory of Simulations and Anatomy Department, University of Poitiers, rue de la Milétrie, 86000 Poitiers, France; Abdominal Surgery Department, University of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Richer
authors.affiliation: Department of Imaging, University Hospital of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: S
authors.initials: S
authors.lastname: Boucebci
authors.affiliation: Department of Imaging, University Hospital of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: S
authors.initials: S
authors.lastname: Vélasco
authors.affiliation: Abdominal Surgery Department, University of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: M
authors.initials: M
authors.lastname: Carretier
authors.affiliation: Anaesthesiology Department, University Hospital of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: B
authors.initials: B
authors.lastname: Debeane
authors.affiliation: Abdominal Oncology Department, University Hospital of Poitiers, rue de la Milétrie, 86000 Poitiers, France.
authors.forename: D
authors.initials: D
authors.lastname: Tougeron
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy*; D053672:Electrochemotherapy / Q000379:methods*; D006801:Humans; D009367:Neoplasm Staging; D010179:Pancreas / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000628:therapy*; D011379:Prognosis
keywords: Cancer; Interventional radiology; Irreversible electroporation; Pancreas; Pancreatic adenocarcinoma