title: Novel use of the medtronic micro vascular plug for PDA closure in preterm infants.
abstract: OBJECTIVE
  To describe a single institution experience with a new endovascular occlusion device used for transcatheter patent ductus arteriosus (PDA) closure in preterm infants.
  
  
  BACKGROUND
  The PDA is a defect largely treated via cardiac catheterization except for the smallest patients.
  
  
  METHODS
  Medical records and catheterization reports of all premature neonates who underwent PDA device closure with the Medtronic Micro Vascular Plug (MVP) (Medtronic, Minneapolis, MN) between September 2015 and June 2016 were reviewed. Procedural details, complications, and short term outcomes were recorded.
  
  
  RESULTS
  Eight premature neonates born at a median gestational age of 28 weeks (23 to 35 weeks) underwent PDA closure with a Medtronic MVP. All devices were deployed via a 4F angled Glide catheter in prograde fashion without arterial access. Median age and weight was 52 days (15-112 days) and 2,550 g (1,800-3,500 g), respectively. Fluoroscopy and echocardiography were utilized for the procedure. Complete closure was achieved in all patients with no procedural complications, pulmonary artery or aortic obstruction or death. One device embolized 9 days after deployment and was successfully retrieved.
  
  
  CONCLUSIONS
  This study describes transcatheter PDA closure with the Medtronic MVP. The major advantage is the ability to deliver the device via a standard catheter in prograde fashion, and avoid the hemodynamic instability produced by rigid delivery sheaths. It also further validates the ability to close the PDA without arterial access, providing improved access to this procedure to smaller and more vulnerable children. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas.
authors.forename: Elizabeth W
authors.initials: EW
authors.lastname: Wang-Giuffre
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas.
authors.forename: John P
authors.initials: JP
authors.lastname: Breinholt
mesh_terms: D001027:Aortography; D001724:Birth Weight; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D004374:Ductus Arteriosus, Patent / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D018618:Echocardiography, Doppler, Color; D005260:Female; D005865:Gestational Age; D006801:Humans; D062071:Infant, Extremely Premature; D007231:Infant, Newborn; D008297:Male; D008499:Medical Records; D011474:Prosthesis Design; D055989:Septal Occluder Device; D013781:Texas; D013997:Time Factors; D016896:Treatment Outcome
keywords: congenital heart disease; patent ductus arteriosus; vascular occlusion