title: The Relationship Between Hearing Thresholds and Hyperandrogenism in Polycystic Ovary Syndrome.
abstract: BACKGROUND The purpose of our study was to investigate the association between polycystic ovary syndrome (PCOS) and hearing thresholds. MATERIAL AND METHODS Forty women diagnosed with PCOS (mean age, 24.33±6.38 years) and 40 healthy women controls (mean age, 26.38±6.75 years) were included in prospective study. Each case was tested with low (250, 500, 1000, and 2000 Hz), high (4000, 6000, and 8000 Hz) and extended high (EH) (9000-20000 Hz) frequency audiometry. The fasting plasma glucose, insulin, FSH, LH, total testosterone, and sex hormone-binding globulin were measured in all patients. RESULTS The mean hearing thresholds at EH frequencies were statistically significantly higher in the PCOS group than in the control group (p=0.001 right ear and p=0.015 left ear). There were significant positive correlations among free testosterone index (FTI) values and hirsutism scores with EH frequency hearing thresholds. CONCLUSIONS At pure-tone audiometry (PTA) EH frequencies, we detected significantly higher hearing thresholds in PCOS patients than in controls. We also determined that elevated FTI and hirsutism score were positively correlated with elevated hearing thresholds in EH frequencies. These findings support that hyperandrogenism can play a role in the elevation of hearing thresholds in PCOS.
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Yuzuncu Yıl University, Van, Turkey.
authors.forename: Mahfuz
authors.initials: M
authors.lastname: Turan
authors.affiliation: Department of Endocrinology and Metabolism, Faculty of Medicine, Yuzuncu Yıl University, Van, Turkey.
authors.forename: Rıfkı
authors.initials: R
authors.lastname: Ucler
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Yuzuncu Yıl University, Van, Turkey.
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Garca
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Kurdoglu
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Yuzuncu Yıl University, Van, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Cankaya
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Yuzuncu Yıl University, Van, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Ayral
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Yuzuncu Yıl University, Van, Turkey.
authors.forename: Nazım
authors.initials: N
authors.lastname: Bozan
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Yuzuncu Yıl University, Van, Turkey.
authors.forename: Ahmet Faruk
authors.initials: AF
authors.lastname: Kıroglu
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
authors.forename: Mertihan
authors.initials: M
authors.lastname: Kurdoglu
mesh_terms: D000293:Adolescent; D000328:Adult; D001301:Audiometry, Pure-Tone / Q000379:methods; D001786:Blood Glucose / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D006309:Hearing / Q000502:physiology*; D006628:Hirsutism / Q000097:blood; D006801:Humans; D017588:Hyperandrogenism / Q000097:blood* / Q000150:complications; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D007986:Luteinizing Hormone / Q000097:blood; D008875:Middle Aged; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000150:complications; D011446:Prospective Studies; D013739:Testosterone / Q000097:blood
chemical_list: D001786:Blood Glucose; D007328:Insulin; D013739:Testosterone; D007986:Luteinizing Hormone