title: Anesthetic implications for patients with Segawa syndrome.
abstract: OBJECTIVE
  To characterize the perioperative course of patients with Segawa syndrome undergoing anesthetic management.
  
  
  METHODS
  Retrospective observational case study.
  
  
  METHODS
  Large tertiary medical center.
  
  
  METHODS
  Patients with Segawa syndrome who underwent procedures requiring anesthetic management at our institution from January 1, 2004, through July 31, 2015.
  
  
  METHODS
  The health records of patients with Segawa syndrome.
  
  
  RESULTS
  Twelve patients with Segawa syndrome underwent 25 procedures requiring anesthetic management, including 20 operations with general anesthesia. Succinylcholine was administered in 6 cases and nondepolarizing neuromuscular blockers in 5 cases, all without adverse effects. Perioperative complications were unrelated to anesthetic management or underlying neurologic condition. In 16 operations, the patients were receiving levodopa therapy at the time of the procedure.
  
  
  CONCLUSIONS
  In this cohort, patients with Segawa syndrome tolerated the anesthetic management, including neuromuscular blocker administration. Although these patients are frequently receiving levodopa therapy, no associated complications were noted.
authors.affiliation: Department of Anesthesiology, Mayo Clinic, Rochester, MN.
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Howze
authors.affiliation: Department of Anesthesiology, Mayo Clinic, Rochester, MN.
authors.forename: Nicholas D
authors.initials: ND
authors.lastname: Will
authors.affiliation: Department of Neurology, Mayo Clinic, Rochester, MN.
authors.forename: Bryan T
authors.initials: BT
authors.lastname: Klassen
authors.affiliation: Department of Anesthesiology, Mayo Clinic, Rochester, MN.
authors.forename: Juraj
authors.initials: J
authors.lastname: Sprung
authors.affiliation: Department of Anesthesiology, Mayo Clinic, Rochester, MN. Electronic address: weingarten.toby@mayo.edu.
authors.forename: Toby N
authors.initials: TN
authors.lastname: Weingarten
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000758:Anesthesia / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D020821:Dystonic Disorders / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011183:Postoperative Complications / Q000503:physiopathology*; D012189:Retrospective Studies
keywords: Anesthesia; Complications; Segawa syndrome