title: Temporomandibular joint chondrosarcoma: a case report and literature review.
abstract: Chondrosarcoma is a malignant tumor that originates from cartilaginous cells and is characterized by cartilage formation. Only 5% to 10% of chondrosarcoma occurs in the head and neck area, and it is uncommon in the temporomandibular joint area. This report describes an unusual case with a rare, large chondrosarcoma in a 47-year-old woman who presented with painless swelling and trismus. Computed tomography showed a large mass approximately 8.5×6.0 cm in size arising adjacent to the lateral pterygoid plate and condyle. There were features suggestive of bone resorption. The tumor was resected in a single block with perilesional tissues, and a great auricular nerve graft was performed because of facial nerve sacrifice. Microscopic examination of sections stained with H&E revealed chondrocytes with irregular nuclei and heterogeneous hyper chromatic tumor cells embedded in the chondrocyte lacuna. The diagnosis was a grade I chondrosarcoma. There was no evidence of recurrence at the 8-month follow-up, and a reconstruction surgery with fibular osteocutaneous free flap was performed. We report this unusual entity and a review of the literature.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Kyungjin
authors.identifier: 0000-0002-0831-0180
authors.initials: K
authors.lastname: Lee
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Seong Hwan
authors.identifier: 0000-0002-6932-6258
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Korea.; Dental Research Institute, Seoul National University, Seoul, Korea.
authors.forename: Soung-Min
authors.identifier: 0000-0002-6916-0489
authors.initials: SM
authors.lastname: Kim
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul, Korea.; Dental Research Institute, Seoul National University, Seoul, Korea.
authors.forename: Hoon
authors.identifier: 0000-0002-9984-8479
authors.initials: H
authors.lastname: Myoung
keywords: Osteosarcoma; Temporomandibular joint