title: Clinical Outcomes After 1 Year of Augmented Insulin Pump Therapy in Patients with Diabetes in a Specialized Diabetes Center in Medellín, Colombia.
abstract: Type 1 diabetes can be difficult to control. Augmented pump therapy (CSII-rtCGM) has become an important tool for controlling blood glucose and decreasing hypoglycemia.
  
  
  
  Describe the results 1 year after starting CSII-rtCGM in patients with diabetes in Medellín, Colombia. This is an observational, retrospective study. Patients with type 1 and type 2 diabetes started on CSII-rtCGM between January 2008 and June 2015 were included. Qualitative variables were analyzed as absolute or relative frequencies. Quantitative variables were obtained through central tendency and dispersion according to the normal distribution of the analyzed variable using Kolmogorov-Smirnov. SPSS 19 from IBM was used.
  
  
  
  Two hundred forty-seven patients were identified, of those 183 were included. The starting HbA1C was 8.7% ± 1.7% and 7.4% ± 0.8% (P < 0.05) 1 year later. 16.5% of patients had been admitted to the hospital before starting CSII-rtCGM, after 1 year the admission rate was 6.0% (P < 0.05). The incidence of severe hypoglycemia at the beginning was 32%, 1 year later it was 7.1%.
  
  
  
  CSII-rtCGM therapy improves glucose control and decreases severe hypoglycemic events and hospital admission rate.
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .|3 Universidad Pontificia Bolivariana , Medellín, Colombia .|5 Grupo de Investigación, Innovación, Desarrollos y Avances en Endocrinología, Medellín, Colombia .|6 Grupo de Investigación de Medicina Interna y Endocrinología, Universidad Pontificia Bolivariana, Medellín, Colombia .
authors.forename: Alex
authors.initials: A
authors.lastname: Ramirez-Rincon
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .|5 Grupo de Investigación, Innovación, Desarrollos y Avances en Endocrinología, Medellín, Colombia .|6 Grupo de Investigación de Medicina Interna y Endocrinología, Universidad Pontificia Bolivariana, Medellín, Colombia .
authors.forename: Jaime
authors.initials: J
authors.lastname: Hincapie-García
authors.affiliation: 2 Clinica Universitaria Bolivariana , Medellín, Colombia .|3 Universidad Pontificia Bolivariana , Medellín, Colombia .|5 Grupo de Investigación, Innovación, Desarrollos y Avances en Endocrinología, Medellín, Colombia .|6 Grupo de Investigación de Medicina Interna y Endocrinología, Universidad Pontificia Bolivariana, Medellín, Colombia .
authors.forename: Claudia Monsalve
authors.initials: CM
authors.lastname: Arango
authors.affiliation: 2 Clinica Universitaria Bolivariana , Medellín, Colombia .|3 Universidad Pontificia Bolivariana , Medellín, Colombia .|5 Grupo de Investigación, Innovación, Desarrollos y Avances en Endocrinología, Medellín, Colombia .|6 Grupo de Investigación de Medicina Interna y Endocrinología, Universidad Pontificia Bolivariana, Medellín, Colombia .
authors.forename: Natalia
authors.initials: N
authors.lastname: Aristizabal
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .
authors.forename: Estefany
authors.initials: E
authors.lastname: Castillo
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .
authors.forename: Gloria
authors.initials: G
authors.lastname: Hincapie
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .
authors.forename: Eliana
authors.initials: E
authors.lastname: Zapata
authors.affiliation: 3 Universidad Pontificia Bolivariana , Medellín, Colombia .
authors.forename: Diana Paola
authors.initials: DP
authors.lastname: Cuesta
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .
authors.forename: Maria
authors.initials: M
authors.lastname: Delgado
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .
authors.forename: Veronica
authors.initials: V
authors.lastname: Abad
authors.affiliation: 3 Universidad Pontificia Bolivariana , Medellín, Colombia .|4 Clinica Las Américas, Medellín, Colombia .
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Torres
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .|3 Universidad Pontificia Bolivariana , Medellín, Colombia .|5 Grupo de Investigación, Innovación, Desarrollos y Avances en Endocrinología, Medellín, Colombia .
authors.forename: Andres
authors.initials: A
authors.lastname: Palacio
authors.affiliation: 1 Clinica Integral de Diabetes-CLID , Medellín, Colombia .|3 Universidad Pontificia Bolivariana , Medellín, Colombia .|5 Grupo de Investigación, Innovación, Desarrollos y Avances en Endocrinología, Medellín, Colombia .
authors.forename: José Fernando
authors.initials: JF
authors.lastname: Botero
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D002648:Child; D003105:Colombia; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use*; D007332:Insulin Infusion Systems; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: Augmented insulin pump therapy; Continuous insulin infusion systems; Diabetic ketoacidosis; HbA1c; Hospital admission; Real-time continuous glucose monitoring system; Severe hypoglycemia