title: Ambulatory blood pressure in hypertensive patients with inclusion criteria for the SPRINT trial.
abstract: We aimed to characterize 24-hour blood pressure (BP) values and categories in patients with inclusion/exclusion criteria of the Systolic Blood Pressure Intervention (SPRINT) trial from the Spanish ABPM Registry. We selected patients older than 50 years, with office systolic BP (SBP) above 130 mm Hg and at high cardiovascular risk, but without diabetes, previous stroke, or symptomatic heart failure. Ambulatory BP was compared among BP categories. A total of 39,132 patients (34%) fulfilled inclusion criteria of SPRINT trial. Ambulatory SBP was considerably lower than office BP, with 42% of patients having daytime values below 130 mm Hg and 21% 24-hour values below 120 mm Hg. In conclusion, more than one-third of the hypertensive population included in the Spanish ABPM Registry can be considered as SPRINT candidates, although one out of five have values of 24-hour SBP below 120 mm Hg. These data suggest that knowledge of ABPM values could be helpful when planning a treatment intensification in high-risk patients.
authors.affiliation: Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Spain. Electronic address: adelasierra@mutuaterrassa.cat.
authors.forename: Alejandro
authors.initials: A
authors.lastname: de la Sierra
authors.affiliation: Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid;IdiPAZ/CIBERESP, Madrid, Spain.
authors.forename: José R
authors.initials: JR
authors.lastname: Banegas
authors.affiliation: CAP Casas Ibáñez, Albacete, Spain.
authors.forename: Juan A
authors.initials: JA
authors.lastname: Divisón
authors.affiliation: Department of Nephrology, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Gorostidi
authors.affiliation: CAP la Mina, University of Barcelona, Barcelona, Spain.
authors.forename: Ernest
authors.initials: E
authors.lastname: Vinyoles
authors.affiliation: Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid;IdiPAZ/CIBERESP, Madrid, Spain.
authors.forename: Juan J
authors.initials: JJ
authors.lastname: de la Cruz
authors.affiliation: Department of Nephrology, Hypertension Unit, Hospital 12 de Octubre, Madrid, Spain.
authors.forename: Julián
authors.initials: J
authors.lastname: Segura
authors.affiliation: Department of Nephrology, Hypertension Unit, Hospital 12 de Octubre, Madrid, Spain.
authors.forename: Luis M
authors.initials: LM
authors.lastname: Ruilope
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D012042:Registries; D012307:Risk Factors; D013030:Spain
chemical_list: D000959:Antihypertensive Agents
keywords: Ambulatory blood pressure monitoring; antihypertensive treatment; blood pressure control; white-coat hypertension