title: Primary spinal intradural extramedullary lymphoma: A novel management strategy.
abstract: Primary spinal intradural extramedullary lymphoma remains a very rare entity in spinal oncology. In this case report, we present the first treatment of a PSIEL diagnosed by cytopathologic analysis alone followed by urgent radio- and chemotherapy in the literature. At 18-month follow-up, our patient was ambulatory with near total imaging resolution of the lesion. In conclusion, surgical excision or biopsy may not be necessary when suspicion for PSIEL exists, and may delay prompt medical and radiation treatment due to necessity for wound healing. Further research into the management of extramedullary lymphoma treatment strategies is warranted.
authors.affiliation: Department of Neurological Surgery, University Hospitals, 11100 Euclid Ave, Cleveland, OH 44122, USA. Electronic address: AngeliqueSaoMai.Do@uhhospitals.org.
authors.forename: Angelique Sao-Mai
authors.initials: AS
authors.lastname: Do
authors.affiliation: Department of Neurological Surgery, University Hospitals, 11100 Euclid Ave, Cleveland, OH 44122, USA. Electronic address: gabriel.smith@uhhospitals.org.
authors.forename: Gabriel A
authors.initials: GA
authors.lastname: Smith
authors.affiliation: Department of Neurological Surgery, University Hospitals, 11100 Euclid Ave, Cleveland, OH 44122, USA. Electronic address: jonathan.pace@uhhospitals.org.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Pace
authors.affiliation: Department of Neurological Surgery, University Hospitals, 11100 Euclid Ave, Cleveland, OH 44122, USA. Electronic address: Alia.hdeib@uhhospitals.org.
authors.forename: Alia
authors.initials: A
authors.lastname: Hdeib
authors.affiliation: Department of Neurological Surgery, University Hospitals, 11100 Euclid Ave, Cleveland, OH 44122, USA. Electronic address: Manish.kasliwal@uhhospitals.org.
authors.forename: Manish K
authors.initials: MK
authors.lastname: Kasliwal
mesh_terms: D000368:Aged; D059248:Chemoradiotherapy / Q000379:methods*; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D013117:Spinal Cord Compression / Q000209:etiology; D013120:Spinal Cord Neoplasms / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging / Q000628:therapy*; D013129:Spinal Puncture
keywords: Lumbar puncture; Lymphoma; Radiotherapy; Spinal cord compression