title: Effects of numerical information on intention to participate in cervical screening among women offered HPV vaccination: a randomised study.
abstract: OBJECTIVE
  To investigate the effects of different types of information about benefits and harms of cervical screening on intention to participate in screening among women in the first cohorts offered human papilloma virus (HPV) vaccination.
  
  
  METHODS
  Randomised survey study.
  
  
  METHODS
  Denmark.
  
  
  METHODS
  A random sample of women from the birth cohorts 1993, 1994 and 1995 drawn from the general population.
  
  
  METHODS
  A web-based questionnaire and information intervention. We randomised potential respondents to one of the following four different information modules about benefits and harms of cervical screening: no information; non-numerical information; and two numerical information modules. Moreover, we provided HPV-vaccinated women in one of the arms with numerical information about benefits and harms in two steps: firstly, information without consideration of HPV vaccination and subsequently information conditional on HPV vaccination.
  
  
  METHODS
  Self-reported intention to participate in cervical screening.
  
  
  RESULTS
  A significantly lower proportion intended to participate in screening in the two groups of women receiving numerical information compared to controls with absolute differences of 10.5 (95% CI: 3.3-17.6) and 7.7 (95% CI: 0.4-14.9) percentage points, respectively. Among HPV-vaccinated women, we found a significantly lower intention to participate in screening after numerical information specific to vaccinated women (OR of 0.38).
  
  
  CONCLUSIONS
  Women are sensitive to numerical information about the benefits and harms of cervical screening. Specifically, our results suggest that HPV-vaccinated women are sensitive to information about the expected changes in benefits and harms of cervical screening after implementation of HPV vaccination. KEY POINTS Women were less likely to participate in cervical screening when they received numerical information about benefits and harms compared to non-numerical or no information. Specifically, numerical information about the potential impact of the reduced risk of cervical cancer among HPV-vaccinated women reduced the intention to participate among vaccinated women.
authors.affiliation: a The Research Unit for General Practice and Section of General Practice, Department of Public Health , University of Copenhagen , Copenhagen K , Denmark.
authors.forename: Mie Sara
authors.initials: MS
authors.lastname: Hestbech
authors.affiliation: b COHERE, Department of Business and Economics and Department of Public Health , University of Southern Denmark , Odense M , Denmark.
authors.forename: Dorte
authors.initials: D
authors.lastname: Gyrd-Hansen
authors.affiliation: a The Research Unit for General Practice and Section of General Practice, Department of Public Health , University of Copenhagen , Copenhagen K , Denmark.
authors.forename: Jakob
authors.initials: J
authors.lastname: Kragstrup
authors.affiliation: a The Research Unit for General Practice and Section of General Practice, Department of Public Health , University of Copenhagen , Copenhagen K , Denmark.
authors.forename: Volkert
authors.initials: V
authors.lastname: Siersma
authors.affiliation: a The Research Unit for General Practice and Section of General Practice, Department of Public Health , University of Copenhagen , Copenhagen K , Denmark.|c Primary Health Care Research Unit , Zealand Region, Denmark.
authors.forename: John
authors.initials: J
authors.lastname: Brodersen
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003657:Decision Making; D003718:Denmark; D005260:Female; D015438:Health Behavior; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D033182:Intention; D008403:Mass Screening; D027383:Papillomaviridae; D053918:Papillomavirus Vaccines; D010342:Patient Acceptance of Health Care; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000517:prevention & control* / Q000821:virology; D014611:Vaccination; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines
keywords: Cervical screening; Denmark; HPV vaccination; cancer screening; general practice; informed choice; medical decision-making; medical prevention