title: Low Cardiac Output After Orthotopic Heart Transplant Secondary to Large Inferior Vena Cava Thrombus After Prothrombin Complex: A Case Report.
abstract: Low cardiac output after orthotopic heart transplant (OHT) may be attributed to inadequate preload, vasodilation, and/or reduced inotropy. Inadequate preload because of an inferior vena cava (IVC) thrombus is a rare cause of low cardiac output and not frequently described in the literature. Although the use of prothrombin complex (PCC) has been associated with thrombus formation, its contribution to life-threatening IVC thrombosis has yet to be described. This case report describes the use of perioperative ultrasound in the diagnosis and management of a low cardiac output state induced by an IVC thrombus in an OHT recipient who received PCC.
authors.affiliation: From the *Anesthesiology Critical Care, †Cardiothoracic Surgery, and ‡Anesthesiology Cardiothoracic Anesthesia, UCSD, San Diego, California.
authors.forename: Kimberly Ann
authors.initials: KA
authors.lastname: Pollock
authors.forename: Zeb
authors.initials: Z
authors.lastname: McMillan
authors.forename: Gert Diederick
authors.initials: GD
authors.lastname: Pretorius
authors.forename: Brett
authors.initials: B
authors.lastname: Cronin
mesh_terms: D001779:Blood Coagulation Factors / Q000009:adverse effects* / Q000627:therapeutic use; D002303:Cardiac Output, Low / Q000175:diagnosis* / Q000000981:diagnostic imaging; D004452:Echocardiography; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging; D020246:Venous Thrombosis / Q000139:chemically induced / Q000175:diagnosis* / Q000000981:diagnostic imaging
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates