title: Effects of Low-Intensity Continuous Ultrasound on Hematological Parameters of Rats.
abstract: BACKGROUND
  Low intensity ultrasound (US) has some well-known bio-effects which are of great importance to be considered. Objective: We conducted the present study to investigate the effects of low intensity continuous ultrasound on blood cells count in rat.
  
  
  METHODS
  Rats were anesthetized and blood samples were collected before US exposure. Then, they were exposed to US with nominal intensity of 0.2 W/cm2 at frequency of 3 MHz for a period of 10 minutes and this protocol was repeated for 7 days. Twenty four hours after the last US exposure, secondary blood samples were collected and the changes in blood parameters were evaluated.
  
  
  RESULTS
  Analysis revealed that platelets, hematocrit (HCT) and hemoglobin (HGB) were significantly different between experimental and sham groups but no difference between sham and control groups was observed. The results show that HCT and HGB of exposed rats were significantly reduced. Conclusion: This study shows that low intensity US may lead to side effects for hematological parameters such as reduction in the levels of HGB and HCT.
authors.affiliation: Medical Physics Department, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran ; Cellular and Molecular Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Mehrpour
authors.affiliation: Medical Physics Department, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Shakeri-Zadeh
authors.affiliation: Medical Students' Research Committee, Faculty of medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
authors.forename: P
authors.initials: P
authors.lastname: Basir
authors.affiliation: Department of Basic Sciences, Faculty of Allied Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
authors.forename: B
authors.initials: B
authors.lastname: Jamei
authors.affiliation: Department of Vascular Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: H
authors.initials: H
authors.lastname: Ghaheri
authors.affiliation: Medical Physics Department, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran ; Cellular and Molecular Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran.
authors.forename: M B
authors.initials: MB
authors.lastname: Shiran
keywords:  Biological Effects;  Blood Cells ;  Continuous Wave ;  Hematological Test ; Low Intensity Ultrasound 