title: RABBIT EARS regulates the transcription of TCP4 during petal development in Arabidopsis.
abstract: Plant organ growth requires the proper transition from cell proliferation to cell expansion and differentiation. The CIN-TCP transcription factor gene TCP4 and its post-transcriptional regulator microRNA319 play a pivotal role in this process. In this study, we identified a pathway in which the product of the C2H2 zinc finger gene RABBIT EARS (RBE) regulates the transcription of TCP4 during Arabidopsis (Arabidopsis thaliana) petal development. RBE directly represses TCP4 during the early stages of petal development; this contributes to the role of RBE in controlling the growth of petal primordia. We also found that the rbe-1 mutant strongly enhanced the petal phenotypes of tcp4soj6 and mir319a, two mutants with compromised miR319 regulation of TCP4 Our results show that transcriptional and post-transcriptional regulation function together to pattern the spatial and temporal expression of TCP4 This in turn controls petal size and shape in Arabidopsis.
authors.affiliation: Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong 518060, P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong 518060, P.R. China.
authors.forename: Yanzhi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong 518060, P.R. China.
authors.forename: Yongxia
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong 518060, P.R. China.
authors.forename: Weiyao
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA.|Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA.
authors.forename: Vivian F
authors.initials: VF
authors.lastname: Irish
authors.affiliation: Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong 518060, P.R. China tengbohuang@szu.edu.cn.|Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA.
authors.forename: Tengbo
authors.identifier: 0000-0002-4762-9653
authors.initials: T
authors.lastname: Huang
mesh_terms: D017360:Arabidopsis / Q000254:growth & development* / Q000502:physiology; D029681:Arabidopsis Proteins / Q000502:physiology*; D047369:Chromatin Immunoprecipitation; D035264:Flowers / Q000254:growth & development* / Q000502:physiology; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D018506:Gene Expression Regulation, Plant / Q000502:physiology; D017403:In Situ Hybridization; D012097:Repressor Proteins / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*
chemical_list: D029681:Arabidopsis Proteins; C509081:RBE protein, Arabidopsis; D012097:Repressor Proteins; C560908:TCP4 protein, Arabidopsis; D014157:Transcription Factors
keywords: 
  RABBIT EARS
  ; 
  TCP4
  ; Arabidopsis; organ growth; petal development; transcription.