title: Leptomeningeal dissemination and vertebral bone involvement in a child with pilocytic astrocytoma.
abstract: In low-grade glioma, metastasis is rarely seen. Few cases of leptomeningeal dissemination have been reported in children. Vertebral bone metastasis has not been reported so far. Herein is described the case of a pediatric patient with the diagnosis of pilocytic astrocytoma, and leptomeningeal dissemination detected at the time of diagnosis, who then received radiotherapy and chemotherapy upon development of vertebral bone metastasis during treatment.
authors.affiliation: Division of Pediatric Oncology, Department of Pediatrics, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Metin
authors.initials: M
authors.lastname: Demirkaya
authors.affiliation: Division of Pediatric Oncology, Department of Pediatrics, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Betül
authors.initials: B
authors.lastname: Sevinir
authors.affiliation: Division of Pediatric Oncology, Department of Pediatrics, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Güler
authors.affiliation: Department of Radiation Oncology, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Candan
authors.initials: C
authors.lastname: Demiröz
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Özgür
authors.initials: Ö
authors.lastname: Taskapilioglu
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Selcuk
authors.initials: S
authors.lastname: Yilmazlar
authors.affiliation: Department of Radiology, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Figen
authors.initials: F
authors.lastname: Palabiyik
authors.affiliation: Department of Pathology, Faculty of Medicine, Uludag University, Bursa, Turkey.
authors.forename: Sahsine
authors.initials: S
authors.lastname: Tolunay
mesh_terms: D001254:Astrocytoma / Q000473:pathology*; D001859:Bone Neoplasms / Q000556:secondary*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology*
keywords: bone metastasis; child; leptomeningeal dissemination; low-grade glioma