title: CCN3: stopping that achy, breaky aorta.
abstract: Abdominal aortic aneurysm (AAA) affects between 2 and 8 % of males over the age of 65. Mortality if ruptured is 85 to 90 %, Recent data by Zhang and colleagues (J Clin Invest 126(4):1282-1299 2016) suggest that CCN3 might be used to treat AAA. This Bits and Bytes summarizes these findings.
authors.affiliation: Departments of Dentistry and Physiology and Pharmacology, University of Western Ontario, Dental Sciences Building, London, ON, N6A 5C1, Canada. Andrew.leask@schulich.uwo.ca.
authors.forename: Andrew
authors.initials: A
authors.lastname: Leask
keywords: Abdominal aortic aneurysm; CCN family; CCN3; Cardiovascular disease; Matricellular proteins; Nov