title: Definition and Management of Borderline Resectable Pancreatic Cancer.
abstract: Patients with localized pancreatic ductal adenocarcinoma seek potentially curative treatment, but this group represents a spectrum of disease. Patients with borderline resectable primary tumors are a unique subset whose successful therapy requires a care team with expertise in medical care, imaging, surgery, medical oncology, and radiation oncology. This team must identify patients with borderline tumors then carefully prescribe and execute a combined treatment strategy with the highest possibility of cure. This article addresses the issues of clinical evaluation, imaging techniques, and criteria, as well as multidisciplinary treatment of patients with borderline resectable pancreatic ductal adenocarcinoma.
authors.affiliation: Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1484, Houston, TX 77030, USA.
authors.forename: Jason W
authors.initials: JW
authors.lastname: Denbo
authors.affiliation: Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1484, Houston, TX 77030, USA. Electronic address: jbflemin@mdanderson.org.
authors.forename: Jason B
authors.initials: JB
authors.lastname: Fleming
mesh_terms: D003131:Combined Modality Therapy; D019468:Disease Management; D006801:Humans; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000628:therapy*
keywords: Borderline resectable pancreatic cancer; Definitions; Management; Pancreatic ductal adenocarcinoma