title: The proteomes of the human eye, a highly compartmentalized organ.
abstract: Proteomics has now published a series of Dataset Briefs on the EyeOme from the HUPO Human Proteome Project with high-quality analyses of the proteomes of these compartments of the human eye: retina, iris, ciliary body, retinal pigment epithelium/choroid, retrobulbar optic nerve, and sclera, with 3436, 2929, 2867, 2755, 2711, and 1945 proteins, respectively. These proteomics resources represent a useful starting point for a broad range of research aimed at developing preventive and therapeutic interventions for the various causes of blindness.
authors.affiliation: Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Gilbert S
authors.initials: GS
authors.lastname: Omenn
mesh_terms: D030562:Databases, Protein; D005123:Eye / Q000378:metabolism*; D006801:Humans; D020543:Proteome / Q000378:metabolism*; D040901:Proteomics; D012160:Retina / Q000378:metabolism; D055213:Retinal Pigment Epithelium / Q000378:metabolism
chemical_list: D020543:Proteome
keywords: Biology and Disease-driven Human Proteome Project; Biomedicine; End Blindness by 2020; Eye proteome; EyeOme; Human Proteome Project