title: Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues.
abstract: A 2D peptidosheet unravels CD47 as a potential biomarker to image hepatocarcinoma and cholangiocarcinoma cells and tissues. Supramolecular assembly between water-soluble 2D MoS2and a peptide probe produces the 2D peptidosheet suited for the profiling of hepatocarcinoma and cholangiocarcinoma tissues over healthy tissues on clinical specimens.
authors.affiliation: International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, the Second Military Medical University, Shanghai, 200433, P. R. China.
authors.forename: Yun-Han
authors.initials: YH
authors.lastname: Ma
authors.affiliation: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai, 200237, P. R. China.
authors.forename: Wei-Tao
authors.initials: WT
authors.lastname: Dou
authors.affiliation: International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, the Second Military Medical University, Shanghai, 200433, P. R. China.
authors.forename: Yu-Fei
authors.initials: YF
authors.lastname: Pan
authors.affiliation: International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, the Second Military Medical University, Shanghai, 200433, P. R. China.
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Dong
authors.affiliation: International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, the Second Military Medical University, Shanghai, 200433, P. R. China.
authors.forename: Ye-Xiong
authors.initials: YX
authors.lastname: Tan
authors.affiliation: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai, 200237, P. R. China.
authors.forename: Xiao-Peng
authors.initials: XP
authors.lastname: He
authors.affiliation: Key Laboratory for Advanced Materials & Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai, 200237, P. R. China.
authors.forename: He
authors.initials: H
authors.lastname: Tian
authors.affiliation: International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, the Second Military Medical University, Shanghai, 200433, P. R. China.
authors.forename: Hong-Yang
authors.initials: HY
authors.lastname: Wang
mesh_terms: D001650:Bile Duct Neoplasms; D001653:Bile Ducts, Intrahepatic; D014408:Biomarkers, Tumor; D051928:CD47 Antigen / Q000737:chemistry*; D006528:Carcinoma, Hepatocellular; D018281:Cholangiocarcinoma; D006801:Humans; D008113:Liver Neoplasms; D010455:Peptides
chemical_list: D014408:Biomarkers, Tumor; D051928:CD47 Antigen; D010455:Peptides
keywords: 2D materials; CD47; biomarkers; cancer; imaging