title: Synthesis of Polydopamine-Like Nanocapsules via Removal of a Sacrificial Mesoporous Silica Template with Water.
abstract: Hollow polymeric polydopamine (PDA) micro-/nanocapsules have been obtained through a very simple, mild, and straightforward method that involves coating of silica mesoporous nanoparticles through an ammonia-triggered polymerization of PDA and the posterior removal of the sacrificial template simply by dispersion in water, without the need of any harsh chemical reagent, either in the presence or absence of active principles, from doxorubicin to iron oxide nanoparticles. To demonstrate the potential of the nanocapsules obtained with this new approach, they have been successfully used as nanocarriers for drug delivery.
authors.affiliation: Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Edificio ICN2, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
authors.forename: Fabiana
authors.identifier: http://orcid.org/0000-0003-2502-0430
authors.initials: F
authors.lastname: Nador
authors.affiliation: Depto. Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Instituto de Investigación Sanitaria Hospital 12 de Octubre, i+12 Universidad Complutense de Madrid, Plaza Ramon y Cajal s/n., 28040, Madrid, Spain.|Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Av. Monforte de Lemos, 3-5. Pabellón 11. Planta 0, 28029, Madrid, Spain.
authors.forename: Eduardo
authors.identifier: http://orcid.org/0000-0002-2549-1745
authors.initials: E
authors.lastname: Guisasola
authors.affiliation: Depto. Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Instituto de Investigación Sanitaria Hospital 12 de Octubre, i+12 Universidad Complutense de Madrid, Plaza Ramon y Cajal s/n., 28040, Madrid, Spain.|Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Av. Monforte de Lemos, 3-5. Pabellón 11. Planta 0, 28029, Madrid, Spain.
authors.forename: Alejandro
authors.identifier: http://orcid.org/0000-0002-9042-8865
authors.initials: A
authors.lastname: Baeza
authors.affiliation: Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Edificio ICN2, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
authors.forename: Miguel Angel Moreno
authors.identifier: http://orcid.org/0000-0003-2410-0682
authors.initials: MA
authors.lastname: Villaecija
authors.affiliation: Depto. Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Instituto de Investigación Sanitaria Hospital 12 de Octubre, i+12 Universidad Complutense de Madrid, Plaza Ramon y Cajal s/n., 28040, Madrid, Spain.|Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Av. Monforte de Lemos, 3-5. Pabellón 11. Planta 0, 28029, Madrid, Spain.
authors.forename: Maria
authors.identifier: http://orcid.org/0000-0002-6104-4889
authors.initials: M
authors.lastname: Vallet-Regí
authors.affiliation: Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Edificio ICN2, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
authors.forename: Daniel
authors.identifier: http://orcid.org/0000-0002-6844-8421
authors.initials: D
authors.lastname: Ruiz-Molina
keywords: catechol; encapsulation; mesoporous materials; nanoparticles; polydopamine