title: Effect of dry heating and ionic gum on the physicochemical and release properties of starch from Dioscorea.
abstract: To meet the ever increasing industrial demand for excipients with desirable properties, modified starch is regarded as an alternative to it. With this in mind, the present study focuses on the modification of starches of Dioscorea from Jharkhand (India) using dry heat treatment with and without ionic gum. Modified starches were prepared using sodium alginate (1% w/w). Native and modified starches were subjected to heat treatment at 130°C for 2h and 4h. The effect of heating and ionic gum on the properties of Dioscorea starch was investigated. The amylose content, water holding capacity, micromeritic properties, swelling power, solubility and morphology of starches were evaluated. Dry heat treatment of starches without gum showed an increment in water-holding capacity after two-hours heating, but no such increment was found after four-hours heating. Oil binding capacity of starches modified with gum varied from 62% to 78%. Strongest effect of heat treatment occurred on the morphology of starches and thereby modified starches showed distorted surface morphology. Amylose content (21.09-21.89%) found to be decreased with the addition of gum which lead to decrease in paste clarity. Starches heated with gum at high-temperature resulted in restrict swelling and slight increase in solubility. Micromeritic properties of the modified starches showed the good flow properties. Further, the modified starches were investigated for in-vitro release studies and that the thermally modified derivatives can be a good prospect in slow release formulations.
authors.affiliation: Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India.
authors.forename: Deepika
authors.initials: D
authors.lastname: Vashisht
authors.affiliation: Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India.
authors.forename: Anima
authors.initials: A
authors.lastname: Pandey
authors.affiliation: Institute of Life Sciences, Vasile Goldis Western University of Arad, Arad 310414, Romania.
authors.forename: Anca
authors.initials: A
authors.lastname: Hermenean
authors.affiliation: Electron Microscopy Service, Universidad Católica San Antonio de Murcia (UCAM), 30107 Guadalupe, Spain.
authors.forename: Maria Josefa
authors.initials: MJ
authors.lastname: Yáñez-Gascón
authors.affiliation: Bioinformatics and High Performance Computing Research Group (BIO-HPC), Computer Science Department, Universidad Católica San Antonio de Murcia (UCAM), 30107 Guadalupe, Spain. Electronic address: hperez@ucam.edu.
authors.forename: Horacio
authors.initials: H
authors.lastname: Pérez-Sánchez
authors.affiliation: Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India. Electronic address: jayarampharm@gmail.com.
authors.forename: K Jayaram
authors.initials: KJ
authors.lastname: Kumar
mesh_terms: D055598:Chemical Phenomena; D027742:Dioscorea / Q000737:chemistry*; D006358:Hot Temperature; D053149:Plant Gums / Q000737:chemistry*; D012995:Solubility; D013213:Starch / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D053149:Plant Gums; D014867:Water; D013213:Starch
keywords: Dioscorea starch; Heat treatment; In-vitro release; Ionic gum