title: Surgery for Gastroesophageal Reflux Disease in the Morbidly Obese Patient.
abstract: The prevalence of gastroesophageal reflux disease (GERD) has mirrored the increase in obesity, and GERD is now recognized as an obesity-related comorbidity. There is growing evidence that obesity, specifically central obesity, is associated with the complications of chronic reflux, including erosive esophagitis, Barrett's esophagus, and esophageal adenocarcinoma. While fundoplication is effective in creating a competent gastroesophageal junction and controlling reflux in most patients, it is less effective in morbidly obese patients. In these patients a bariatric operation has the ability to correct both the obesity and the abnormal reflux. The Roux-en-Y gastric bypass is the preferred procedure.
authors.affiliation: Department of Surgery, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
authors.forename: Meredith C
authors.initials: MC
authors.lastname: Duke
authors.affiliation: Department of Surgery, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Farrell
mesh_terms: D050110:Bariatric Surgery / Q000379:methods*; D004943:Esophagogastric Junction / Q000601:surgery; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000150:complications / Q000601:surgery*; D006801:Humans; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*
keywords: Roux-en-Y gastric bypass; gastroesophageal reflux disease; laparoscopic fundoplication; morbid obesity; sleeve gastrectomy; transdiaphragmatic pressure gradient