title: Vagus nerve stimulator-related speech/exercise induced cough.
abstract: Vagal nerve stimulation (VNS) therapy is an effective adjunctive treatment for chronic or recurrent treatment resistant depression. Although considered a safe procedure, increasing output current can be associated with stimulation induced side effects. We report the first case of dry cough induced by speech and mild exercise, occurring in the off mode following implantation of a vagal nerve stimulator (VNSor). We discuss the possible pathophysiology and the potential treatment options of this rare complication.
authors.affiliation: Department of Neurosurgery, University of British-Columbia, Vancouver General Hospital, 855 West 12th Ave, Vancouver V5Z 1M9, Canada. Electronic address: charlotte.dandurand@alumni.ubc.ca.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Dandurand
authors.affiliation: Department of Neurosurgery, University of Montreal Medical Center, 1560 East Sherbrooke Street, Montreal H2L 4M1, Canada. Electronic address: pierre-olivier.champagne@umontreal.ca.
authors.forename: Pierre-Olivier
authors.initials: PO
authors.lastname: Champagne
authors.affiliation: Department of Neurosurgery, University of Montreal Medical Center, 1560 East Sherbrooke Street, Montreal H2L 4M1, Canada. Electronic address: karimelayoubi@hotmail.com.
authors.forename: Karim
authors.initials: K
authors.lastname: Elayoubi
authors.affiliation: Department of Neurosurgery, University of Montreal Medical Center, 1560 East Sherbrooke Street, Montreal H2L 4M1, Canada. Electronic address: alexandergweil@gmail.com.
authors.forename: Alexander G
authors.initials: AG
authors.lastname: Weil
authors.affiliation: Department of Psychiatry, University of Montreal Medical Center, 1560 East Sherbrooke Street, Montréal H2L 4M1, Canada. Electronic address: paul.lesperance@umontreal.ca.
authors.forename: Paul
authors.initials: P
authors.lastname: Lespérence
authors.affiliation: Department of Neurosurgery, University of Montreal Medical Center, 1560 East Sherbrooke Street, Montreal H2L 4M1, Canada. Electronic address: alain.bouthillier@umontreal.ca.
authors.forename: Alain
authors.initials: A
authors.lastname: Bouthillier
mesh_terms: D003371:Cough / Q000209:etiology*; D003863:Depression / Q000628:therapy*; D004567:Electrodes, Implanted / Q000009:adverse effects; D015444:Exercise; D006801:Humans; D008297:Male; D008875:Middle Aged; D013060:Speech; D055536:Vagus Nerve Stimulation / Q000009:adverse effects*
keywords: Complication; Cough; Depression; Vagal nerve stimulator