title: Extracellular vesicles released from chronic lymphocytic leukemia cells exhibit a disease relevant mRNA signature and transfer mRNA to bystander cells.
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany.
authors.forename: Katrin S
authors.initials: KS
authors.lastname: Reiners
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany.
authors.forename: Olga
authors.initials: O
authors.lastname: Shatnyeva
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany.|Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases, CECAD, Germany.
authors.forename: Elena
authors.initials: E
authors.lastname: Vasyutina
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany.
authors.forename: Teresa
authors.initials: T
authors.lastname: Bösl
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany.
authors.forename: Hinrich P
authors.initials: HP
authors.lastname: Hansen
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany.|Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases, CECAD, Germany.|Center of Integrated Oncology Köln Bonn, CIO, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Hallek
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany.|Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases, CECAD, Germany.|Center of Integrated Oncology Köln Bonn, CIO, Germany.
authors.forename: Marco
authors.initials: M
authors.lastname: Herling
authors.affiliation: Department I of Internal Medicine, University Hospital of Cologne, Germany poggevon@staff.uni-marburg.de.|Clinic for Hematology, Oncology and Immunology, Experimental Tumor Research, Center for Tumor Biology and Immunology, Philipps University, Marburg, Germany.
authors.forename: Elke Pogge
authors.initials: EP
authors.lastname: von Strandmann
mesh_terms: D015703:Antigens, CD / Q000235:genetics / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D024201:Bystander Effect / Q000235:genetics* / Q000276:immunology; D000067128:Extracellular Vesicles / Q000737:chemistry* / Q000276:immunology / Q000473:pathology; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D009363:Neoplasm Proteins / Q000235:genetics* / Q000276:immunology; D011518:Proto-Oncogene Proteins / Q000235:genetics / Q000276:immunology; D000072260:RNA Splicing Factors / Q000235:genetics / Q000276:immunology; D034443:RNA Transport; D012333:RNA, Messenger / Q000235:genetics* / Q000276:immunology; D015398:Signal Transduction; D000072377:Syk Kinase / Q000235:genetics / Q000276:immunology; D051217:Toll-Like Receptor 9 / Q000235:genetics / Q000276:immunology; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics / Q000276:immunology; D019061:src-Family Kinases / Q000235:genetics / Q000276:immunology
chemical_list: D015703:Antigens, CD; D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins; D000072260:RNA Splicing Factors; D012333:RNA, Messenger; C090851:TCL1A protein, human; C495371:TLR9 protein, human; D051217:Toll-Like Receptor 9; D014409:Tumor Necrosis Factor-alpha; C000606896:SYK protein, human; D000072377:Syk Kinase; C060902:lyn protein-tyrosine kinase; D019061:src-Family Kinases