title: Clinical profile and outcomes of pediatric endogenous endophthalmitis: A report of 11 cases from South India.
abstract: OBJECTIVE
  To study the clinical profile and outcomes of pediatric endogenous endophthalmitis from a tertiary eye hospital in South India.
  
  
  METHODS
  A total of 13 eyes of 11 children presented to us with varied symptoms and presentations of endogenous endophthalmitis, over a five-year period from January 2010 to December 2015 were studied. Except for two eyes of a patient, vitreous aspirates were cultured from all 11 eyes to isolate the causative organism. These eleven eyes also received intravitreal injections. All patients were treated with systemic antibiotics.
  
  
  RESULTS
  Two cases had bilateral endophthalmitis. Ages ranged from 4 d to 11 years. Five cases were undiagnosed and treated, before being referred to our center. Ten of the 13 eyes underwent a core vitrectomy. The vitrectomy was done at an average on the second day after presenting (range 0-20 d). Five of the 11 vitreous aspirates showed isolates. The incriminating organisms were bacteria in three and fungus in two. An underlying predisposing factor was found in seven patients. At a mean follow-up 21.5 mo, outcome was good in 7 eyes of 6 cases (54%), five eyes of four cases (38%) ended up with phthisis bulbi while one child died of systemic complications.
  
  
  CONCLUSIONS
  Endogenous endophthalmitis is a challenge for ophthalmologists. Early diagnosis and intervention is the key for a better outcome.
authors.affiliation: Gayatri Murugan, Parag K Shah, Venkatapathy Narendran, Department of Pediatric Retina, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore 641014, Tamil Nadu, India.
authors.forename: Gayatri
authors.initials: G
authors.lastname: Murugan
authors.affiliation: Gayatri Murugan, Parag K Shah, Venkatapathy Narendran, Department of Pediatric Retina, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore 641014, Tamil Nadu, India.
authors.forename: Parag K
authors.initials: PK
authors.lastname: Shah
authors.affiliation: Gayatri Murugan, Parag K Shah, Venkatapathy Narendran, Department of Pediatric Retina, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore 641014, Tamil Nadu, India.
authors.forename: Venkatapathy
authors.initials: V
authors.lastname: Narendran
keywords: Endogenous endophthalmitis; Fungal; Outcomes; Pediatric; South India