title: Successful drug-coated balloon angioplasty and single anti-platelet therapy to treat an ischaemic stroke patient with haemorrhage and acute coronary syndrome.
abstract: A 55-year-old male presented with two challenging problems, i.e. acute coronary syndrome (ACS) and a major bleeding episode. He first presented with ischaemic stroke and was treated with thrombolysis. However this was complicated by haemorrhagic transformation. He subsequently developed ACS with urgent coronary angiography demonstrating a critical stenosis in the proximal left anterior descending artery. Percutaneous coronary intervention (PCI) was deemed necessary but we were mindful of causing bleeding complications from the use of anti-thrombotic therapy. Despite the complexities, we used a novel approach in terms of PCI strategy and anti-platelet regimen (drug-coated balloon angioplasty and a single anti-platelet therapy) and achieved a successful outcome.
authors.affiliation: a Department of Cardiology , Tan Tock Seng Hospital , Singapore.
authors.forename: Hee Hwa
authors.initials: HH
authors.lastname: Ho
authors.affiliation: a Department of Cardiology , Tan Tock Seng Hospital , Singapore.
authors.forename: Kwang How
authors.initials: KH
authors.lastname: Mok
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D000800:Angioplasty, Balloon / Q000295:instrumentation / Q000379:methods; D001241:Aspirin / Q000008:administration & dosage*; D001921:Brain / Q000000981:diagnostic imaging; D002545:Brain Ischemia / Q000150:complications / Q000188:drug therapy; D017023:Coronary Angiography / Q000379:methods; D054855:Drug-Eluting Stents; D004452:Echocardiography / Q000379:methods; D004562:Electrocardiography / Q000379:methods; D006801:Humans; D020300:Intracranial Hemorrhages / Q000188:drug therapy / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin
keywords: Aspirin; drug-coated balloon; haemorrhage; stroke