title: Novel Developments in Leukopenia and Pancytopenia.
abstract: Cytopenias are not disease entities in and of themselves; rather, they are the expression of various underlying disease processes. Careful attention to details in patients' presentation, careful history and examination, as well as attention to the ancillary parameters of the complete blood count with a peripheral blood smear can point the clinician toward the appropriate workup. Causes of cytopenias can be inherited or acquired; the latter include medication related, autoimmune, or neoplastic causes. Emergencies need to be recognized in a timely fashion and expert consultation obtained.
authors.affiliation: Department of Medicine, St. Mary's Hospital, Waterbury, CT, USA.
authors.forename: Chisom
authors.initials: C
authors.lastname: Onuoha
authors.affiliation: Department of Medicine, St. Mary's Hospital, Waterbury, CT, USA.
authors.forename: Junaid
authors.initials: J
authors.lastname: Arshad
authors.affiliation: Department of Pathology, Yale University School of Medicine, New Haven, CT, USA; Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: John
authors.initials: J
authors.lastname: Astle
authors.affiliation: Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Mina
authors.initials: M
authors.lastname: Xu
authors.affiliation: Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, 300 George Street, 786E, New Haven, CT 06511, USA. Electronic address: Stephanie.halene@yale.edu.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Halene
mesh_terms: D006403:Hematologic Tests; D006801:Humans; D007970:Leukopenia / Q000175:diagnosis* / Q000209:etiology*; D010198:Pancytopenia / Q000175:diagnosis* / Q000209:etiology*; D011320:Primary Health Care
keywords: Aleukemic leukemia; Clonal hematopoiesis; Hemophagocytosis; Large granular lymphocytosis; Leukopenia; Neutropenia; Pancytopenia