title: Investigating the Cellular and Metabolic Responses of World-Class Canoeists Training: A Sportomics Approach.
abstract: (1) Background: We have been using the Sportomics approach to evaluate biochemical and hematological changes in response to exercise. The aim of this study was to evaluate the metabolic and hematologic responses of world-class canoeists during a training session; (2) Methods: Blood samples were taken at different points and analyzed for their hematological properties, activities of selected enzymes, hormones, and metabolites; (3) Results: Muscle stress biomarkers were elevated in response to exercise which correlated with modifications in the profile of white blood cells, where a leukocyte rise was observed after the canoe session. These results were accompanied by an increase in other exercise intensity parameters such as lactatemia and ammonemia. Adrenocorticotropic hormone and cortisol increased during the exercise sessions. The acute rise in both erythrocytes and white blood profile were probably due to muscle cell damage, rather than hepatocyte integrity impairment; (4) Conclusion: The cellular and metabolic responses found here, together with effective nutrition support, are crucial to understanding the effects of exercise in order to assist in the creation of new training and recovery planning. Also we show that Sportomics is a primal tool for training management and performance improvement, as well as to the understanding of metabolic response to exercise.
authors.affiliation: Laboratory of Protein Biochemistry, Federal University of State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil. wagscoelho@hotmail.com.|Department of Biochemistry and Sportomics, Olympic Laboratory, Brazil Olympic Committee, Rio de Janeiro 22631-910, Brazil. wagscoelho@hotmail.com.
authors.forename: Wagner Santos
authors.initials: WS
authors.lastname: Coelho
authors.affiliation: Laboratory of Protein Biochemistry, Federal University of State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil. luisviveirosdecastro@gmail.com.
authors.forename: Luis
authors.initials: L
authors.lastname: Viveiros de Castro
authors.affiliation: Laboratory of Protein Biochemistry, Federal University of State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil. bethcataldi@gmail.com.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Deane
authors.affiliation: Laboratory of Protein Biochemistry, Federal University of State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil. amvfranca@gmail.com.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Magno-França
authors.affiliation: Laboratory of Protein Biochemistry, Federal University of State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil. abassini@me.com.|Department of Biochemistry and Sportomics, Olympic Laboratory, Brazil Olympic Committee, Rio de Janeiro 22631-910, Brazil. abassini@me.com.
authors.forename: Adriana
authors.initials: A
authors.lastname: Bassini
authors.affiliation: Laboratory of Protein Biochemistry, Federal University of State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil. cameron@unirio.br.|Department of Biochemistry and Sportomics, Olympic Laboratory, Brazil Olympic Committee, Rio de Janeiro 22631-910, Brazil. cameron@unirio.br.
authors.forename: Luiz-Claudio
authors.initials: LC
authors.lastname: Cameron
mesh_terms: D000596:Amino Acids; D056352:Athletes; D015415:Biomarkers; D004734:Energy Metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D018482:Muscle, Skeletal / Q000502:physiology; D013177:Sports; D013312:Stress, Physiological / Q000502:physiology
chemical_list: D000596:Amino Acids; D015415:Biomarkers
keywords: ammonia; biochemistry of exercise; exercise intensity biomarkers; metabolism; physical stress response; urate