title: Gastritis profunda cystica presenting as gastric outlet obstruction and mimicking cancer: A case report.
abstract: Gastritis cystica profunda (GCP) is a rare, benign lesion of the stomach characterized by polypoid hyperplasia and/or ulcerated mucosal lesion and cystic dilatation of the gastric glands extending into the submucosa or muscularis propria of the stomach. Its etiology and pathogenesis are still incompletely understood. The most important factor is assumed to be a history of prior gastric surgery. We herein present a case of a young adult female with upper gastrointestinal (GI) symptoms. She underwent upper GI endoscopy twice, which revealed pyloric narrowing and intramural mass. Gastric endoscopic mucosal biopsies were performed, but no tumor was identified and her symptoms persisted. Imaging studies also revealed a mass lesion. Open laparotomy and partial gastrectomy with histopathology of the resected specimen revealed the true nature of the lesion. Surgery also improved her symptoms. GCP should be kept in the differential diagnosis of gastric mural mass lesions.
authors.affiliation: Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan.
authors.forename: Muhammad Osama
authors.initials: MO
authors.lastname: Butt
authors.affiliation: Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan.
authors.forename: Nasir Hassan
authors.initials: NH
authors.lastname: Luck
authors.affiliation: Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan.
authors.forename: Syed Mujahid
authors.initials: SM
authors.lastname: Hassan
authors.affiliation: Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan.
authors.forename: Zaigham
authors.initials: Z
authors.lastname: Abbas
authors.affiliation: Department of Histopathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Mubarak
keywords: Endoscopy; herniation; histopathology; partial gastrectomy; pyloric mass