title: Self-Reported Physical Activity, Quality of Life, and Psychological Status in Relation to Plasma 25-Hydroxyvitamin D Concentration in Patients Treated with Hemodialysis.
abstract: OBJECTIVE
  Vitamin D status is announced among factors that may influence physical performance and mental health. Our aim was to evaluate self-reported physical activity, quality of life, psychiatric functioning, and affects with respect to plasma 25-hydroxyvitamin D [25(OH)D] concentrations in HD patients.
  
  
  METHODS
  The study was carried out in HD patients not receiving vitamin D supplements (n = 112). IPAQ-L, QLI-D, GHQ-28, and PANAS were used in psychological evaluations. Plasma 25(OH)D concentration was determined by a chemiluminescent microparticle immunoassay.
  
  
  RESULTS
  Plasma 25(OH)D level was suboptimal in all patients (14.6 ± 4.1 ng/ml). Adjusted correlates of 25(OH)D concentration included the GG genotype of GC rs7041 (β±SE: 1.77± 0.70, P=0.014), female sex (β±SE: -2.19±0.75, P=0.004), and treatment with high flux HD (β±SE: 2.59±0.69, P=0.0003). In adjusted analyses, circulating 25(OH)D showed the independent association with total activity related to domestic and gardening domain (β±SE: 53.2±23.8, P=0.028), and with moderate-intensity activities (β±SE: 54.9±27.4, P=0.048), but not with any of quality of life, psychiatric functioning, or affects measures.
  
  
  CONCLUSIONS
  Vitamin D status is independently positively associated with physical activity in HD patients. Quality of life and mental health do not seem to be associated with circulating 25(OH)D under condition of its suboptimal levels.
authors.affiliation: Department of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, Poznań Poland.
authors.forename: Alicja E
authors.initials: AE
authors.lastname: Grzegorzewska
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Izdebska
authors.forename: Leszek
authors.initials: L
authors.lastname: Niepolski
authors.forename: Wojciech
authors.initials: W
authors.lastname: Warchoł
authors.forename: Paweł P
authors.initials: PP
authors.lastname: Jagodziński
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D011788:Quality of Life; D006435:Renal Dialysis; D057566:Self Report; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D