title: Does Only Size Matter or Is There Still a Place for Single-Center Studies in the Era of Big Data?
authors.affiliation: From the *General Intensive Care Unit of the Shaare Zedek Medical Centre and the Hebrew University Faculty of Medicine, Jerusalem, Israel; and †Department of Anesthesia and Critical Care, University of Chicago, Chicago, Illinois.
authors.forename: Sharon
authors.initials: S
authors.lastname: Einav
authors.forename: Michael
authors.initials: M
authors.lastname: O'Connor
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods* / Q000706:statistics & numerical data; D000068598:Data Accuracy; D003627:Data Interpretation, Statistical; D057225:Data Mining / Q000379:methods* / Q000706:statistics & numerical data; D016208:Databases, Factual / Q000706:statistics & numerical data; D006801:Humans; D015233:Models, Statistical; D011336:Probability; D018401:Sample Size