title: Association between parity and ovarian reserve in reproductive age women.
abstract: OBJECTIVE
  A number of factors affect ovarian reserve. In this study, we investigate the association between parity and ovarian reserve in reproductive age women.
  
  
  METHODS
  This cross-sectional study was conducted on 186 women aged 20-35 years. The participants were divided into two main groups. Group A (n=93) included women with at least one parity (pregnancy after 28 weeks), while group B (n=93) included women with no history of pregnancy. We evaluated the following factors related to ovarian reserve: follicle-stimulating hormone (FSH), ovarian antral follicles, anti-Müllerian hormone (AMH), and ovarian volume.
  
  
  RESULTS
  A total of 186 women with a mean age of 27.83±4.49years enrolled in this study. There was a difference in mean AMH between the nulliparous (2.53±1.90ng/ml) and multiparous (3.54±1.42ng/ml) groups (p<0.001). FSH levels were from 5.27±1.8mIU/mL in nulliparous women to 5.01±1.9mIU/mL in multiparous women, which did not significantly differ (p=0.36). Antral follicles and ovarian size in multiparous women increased significantly (p<0.001).
  
  
  CONCLUSIONS
  Parity has a significant association with higher levels of ovarian reserve markers.
authors.affiliation: Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran; Department of Endocrinology and Female Infertility at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
authors.forename: Ashraf
authors.initials: A
authors.lastname: Moini
authors.affiliation: Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran.
authors.forename: Manigeh
authors.initials: M
authors.lastname: Hedayatshodeh
authors.affiliation: Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran. Electronic address: rayh_h@yahoo.com.
authors.forename: Reihaneh
authors.initials: R
authors.lastname: Hosseini
authors.affiliation: Research Development Center, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran.
authors.forename: Hadith
authors.initials: H
authors.lastname: Rastad
mesh_terms: D000328:Adult; D000367:Age Factors; D054304:Anti-Mullerian Hormone / Q000097:blood; D015415:Biomarkers / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D043373:Follicle Stimulating Hormone, Human / Q000097:blood; D006782:Hospitals, Special; D006786:Hospitals, Urban; D006801:Humans; D007492:Iran; D016014:Linear Models; D008598:Menstruation / Q000097:blood; D009929:Organ Size; D006080:Ovarian Follicle / Q000000981:diagnostic imaging* / Q000254:growth & development; D065851:Ovarian Reserve; D010053:Ovary / Q000000981:diagnostic imaging / Q000254:growth & development; D010298:Parity; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D015415:Biomarkers; D043373:Follicle Stimulating Hormone, Human; D054304:Anti-Mullerian Hormone
keywords: Anti-Müllerian hormone; Ovarian reserve; Parity