title: One Step Forward in the Challenging Arena of MLL-AF4 Leukemia.
abstract: MLL-AF4 leukemia is the predominant infant acute leukemia and has a poor prognosis. No current experimental models accurately reflect the human disease. Lin et al., in this issue of Cancer Cell, describe their model that recapitulates multiple key aspects of this aggressive disease, facilitating future mechanistic and preclinical studies.
authors.affiliation: Oncology Research Institute and Department of Medicine, Loyola University Chicago, Maywood, IL 60153, USA. Electronic address: nzelezn@luc.edu.
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Zeleznik-Le
mesh_terms: D006801:Humans; D007938:Leukemia; D051788:Myeloid-Lymphoid Leukemia Protein; D015514:Oncogene Proteins, Fusion
chemical_list: D015514:Oncogene Proteins, Fusion; D051788:Myeloid-Lymphoid Leukemia Protein