title: A new species of Trichoderma hypoxylon harbours abundant secondary metabolites.
abstract: Some species of Trichoderma are fungicolous on fungi and have been extensively studied and commercialized as biocontrol agents. Multigene analyses coupled with morphology, resulted in the discovery of T. hypoxylon sp. nov., which was isolated from surface of the stroma of Hypoxylon anthochroum. The new taxon produces Trichoderma- to Verticillium-like conidiophores and hyaline conidia. Phylogenetic analyses based on combined ITS, TEF1-α and RPB2 sequence data indicated that T. hypoxylon is a well-distinguished species with strong bootstrap support in the polysporum group. Chemical assessment of this species reveals a richness of secondary metabolites with trichothecenes and epipolythiodiketopiperazines as the major compounds. The fungicolous life style of T. hypoxylon and the production of abundant metabolites are indicative of the important ecological roles of this species in nature.
authors.affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences (CASIM), No. 3 Park 1, West Beichen Road, Chaoyang District, Beijing 100101, China.|Center of Excellence in Fungal Research, and School of Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
authors.forename: Jingzu
authors.initials: J
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences (CASIM), No. 3 Park 1, West Beichen Road, Chaoyang District, Beijing 100101, China.
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Pei
authors.affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences (CASIM), No. 3 Park 1, West Beichen Road, Chaoyang District, Beijing 100101, China.
authors.forename: Erwei
authors.initials: E
authors.lastname: Li
authors.affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences (CASIM), No. 3 Park 1, West Beichen Road, Chaoyang District, Beijing 100101, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.affiliation: Center of Excellence in Fungal Research, and School of Science, Mae Fah Luang University, Chiang Rai, 57100, Thailand.
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Hyde
authors.affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences (CASIM), No. 3 Park 1, West Beichen Road, Chaoyang District, Beijing 100101, China.|Joint Laboratory of Applied Microbial Technology, CASIM and Institute of Biology limited Liability Company, Henan Academy of Sciences, Zheng Zhou, 45002, China.
authors.forename: Wen-Bing
authors.initials: WB
authors.lastname: Yin
authors.affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences (CASIM), No. 3 Park 1, West Beichen Road, Chaoyang District, Beijing 100101, China.|Joint Laboratory of Applied Microbial Technology, CASIM and Institute of Biology limited Liability Company, Henan Academy of Sciences, Zheng Zhou, 45002, China.
authors.forename: Xingzhong
authors.initials: X
authors.lastname: Liu
mesh_terms: D004271:DNA, Fungal / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000235:genetics; D005656:Fungal Proteins / Q000235:genetics; D055442:Metabolome; D025282:Mycelium / Q000145:classification / Q000166:cytology / Q000235:genetics / Q000378:metabolism; D010802:Phylogeny; D064210:Secondary Metabolism; D017422:Sequence Analysis, DNA; D013172:Spores, Fungal / Q000145:classification / Q000166:cytology / Q000235:genetics / Q000378:metabolism; D014242:Trichoderma / Q000145:classification / Q000166:cytology / Q000235:genetics* / Q000378:metabolism
chemical_list: D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer; D005656:Fungal Proteins