title: Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment.
authors.affiliation: Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
authors.forename: E
authors.initials: E
authors.lastname: Roekevisch
authors.affiliation: Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
authors.forename: M M G
authors.initials: MMG
authors.lastname: Leeflang
authors.affiliation: Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
authors.forename: M E
authors.initials: ME
authors.lastname: Schram
authors.affiliation: Centre for Dermatology and Genetic Medicine, University of Dundee, Dundee, U.K.
authors.forename: L E
authors.initials: LE
authors.lastname: Campbell
authors.affiliation: Centre for Dermatology and Genetic Medicine, University of Dundee, Dundee, U.K.
authors.forename: W H
authors.initials: WH
authors.lastname: Irwin McLean
authors.affiliation: Academic Medical Center, Coronel Institute of Occupational Health, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Kezic
authors.affiliation: Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
authors.forename: J D
authors.initials: JD
authors.lastname: Bos
authors.affiliation: Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
authors.forename: P I
authors.initials: PI
authors.lastname: Spuls
authors.affiliation: Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
authors.forename: M A
authors.initials: MA
authors.lastname: Middelkamp-Hup
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use*; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000235:genetics; D005260:Female; D000091344:Filaggrin Proteins; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007381:Intermediate Filament Proteins / Q000235:genetics*; D000073658:Loss of Function Mutation / Q000235:genetics*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: C000717249:FLG protein, human; D000091344:Filaggrin Proteins; D007166:Immunosuppressive Agents; D007381:Intermediate Filament Proteins; D001379:Azathioprine; D008727:Methotrexate