title: Cryptochromes Orchestrate Transcription Regulation of Diverse Blue Light Responses in Plants.
abstract: Blue light affects many aspects of plant growth and development throughout the plant lifecycle. Plant cryptochromes (CRYs) are UV-A/blue light photoreceptors that play pivotal roles in regulating blue light-mediated physiological responses via the regulated expression of more than one thousand genes. Photoactivated CRYs regulate transcription via two distinct mechanisms: indirect promotion of the activity of transcription factors by inactivation of the COP1/SPA E3 ligase complex or direct activation or inactivation of at least two sets of basic helix-loop-helix transcription factor families by physical interaction. Hence, CRYs govern intricate mechanisms that modulate activities of transcription factors to regulate multiple aspects of blue light-responsive photomorphogenesis. Here, we review recent progress in dissecting the pathways of CRY signaling and discuss accumulating evidence that shows how CRYs regulate broad physiological responses to blue light.
authors.affiliation: Basic Forestry and Proteomics Research Center, Fujian Agriculture and Forestry University, Fuzhou, China.
authors.forename: Zhaohe
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Basic Forestry and Proteomics Research Center, Fujian Agriculture and Forestry University, Fuzhou, China.|College of Forestry, Fujian Agriculture and Forestry University, Fuzhou, China.
authors.forename: Bobin
authors.initials: B
authors.lastname: Liu
authors.affiliation: Basic Forestry and Proteomics Research Center, Fujian Agriculture and Forestry University, Fuzhou, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Su
authors.affiliation: Basic Forestry and Proteomics Research Center, Fujian Agriculture and Forestry University, Fuzhou, China.
authors.forename: Jiakai
authors.initials: J
authors.lastname: Liao
authors.affiliation: Department of Molecular, Cell & Developmental Biology, University of California, Los Angeles, CA.
authors.forename: Chentao
authors.initials: C
authors.lastname: Lin
authors.affiliation: Basic Forestry and Proteomics Research Center, Fujian Agriculture and Forestry University, Fuzhou, China.
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Oka
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000502:physiology / Q000528:radiation effects; D051792:Basic Helix-Loop-Helix Proteins / Q000378:metabolism; D003116:Color; D056931:Cryptochromes / Q000378:metabolism / Q000502:physiology*; D018506:Gene Expression Regulation, Plant / Q000502:physiology* / Q000528:radiation effects; D008027:Light; D015398:Signal Transduction; D014158:Transcription, Genetic / Q000502:physiology* / Q000528:radiation effects
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D056931:Cryptochromes