title: Epigenetics in diagnosis of colorectal cancer.
abstract: Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the early diagnosis of CRC. This will serve as the boon to the clinical management of the disease.
authors.affiliation: Basic Medical Sciences Department, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Kingdom of Saudi Arabia.
authors.forename: Aga Syed
authors.initials: AS
authors.lastname: Sameer
authors.affiliation: Department of Biochemistry , Kashmir University, Hazratbal, Srinagar, Kashmir, INDIA.
authors.forename: Saniya
authors.initials: S
authors.lastname: Nissar
keywords: Biomarkers; Epigenetics; Hypermethylation; olorectal Cancer