title: Early Description of Diet-Induced Blistering Skin Diseases in Medieval Persia: Avicenna's Point of View.
abstract: Pemphigus is an autoimmune blistering skin disease that is strongly associated with different environmental factors. Among these, nutritional factors are considered to trigger pemphigus; however, their role may be underestimated. Investigated more recently in conventional medicine, this causative bond between dietary factors and blistering skin diseases was mentioned by Persian scholars such as Avicenna a thousand years ago. Avicenna, a well-known Persian physician and philosopher, who could be considered a pioneer in dermatology, discussed skin diseases in a chapter inThe Canon of Medicine. He accounted for some nutritional triggers for skin blisters (mentioned as "hot swellings"), such as onion, garlic, leek, pepper, and wine. His precise description of causative factors based on principles of traditional Persian medicine (TPM) is appreciable and might well lead us to find more efficient ways for the prevention and treatment of blistering skin diseases.
authors.affiliation: Department of Traditional Persian Medicine, School of Traditional Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.|Tehran University of Medical Sciences, Tehran, Iran; and the Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.|Essence of Parsiyan Wisdom Institute, Traditional Medicine and Medicinal Plant Incubator, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Atarzadeh
authors.affiliation: Tehran University of Medical Sciences, Tehran, Iran; and the Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.|Essence of Parsiyan Wisdom Institute, Traditional Medicine and Medicinal Plant Incubator, Shiraz University of Medical Sciences, Shiraz, Iran; babakdaneshfard@gmail.com; daneshfard@sums.ac.ir.
authors.forename: Babak
authors.initials: B
authors.lastname: Daneshfard
authors.affiliation: Shiraz Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.|Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Ladan
authors.initials: L
authors.lastname: Dastgheib
authors.affiliation: Essence of Parsiyan Wisdom Institute, Traditional Medicine and Medicinal Plant Incubator, Shiraz University of Medical Sciences, Shiraz, Iran.|Department of Traditional Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Amir-Mohammad
authors.initials: AM
authors.lastname: Jaladat
authors.affiliation: Departments of Pharmacognosy, Shiraz University of Medical Sciences, Shiraz, Iran.|Traditional Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Amin
mesh_terms: D004032:Diet / Q000009:adverse effects / Q000266:history; D005502:Food / Q000009:adverse effects / Q000266:history*; D049691:History, Medieval; D006801:Humans; D010392:Pemphigus / Q000209:etiology / Q000266:history; D019071:Persia; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology / Q000266:history* / Q000517:prevention & control