title: Autoinflammatory Skin Disease: A Review of Concepts and Applications to General Dermatology.
abstract: We provide an up-to-date summary of important concepts of autoinflammation as well as describe important but rare monogenic autoinflammatory disorders that may present with cutaneous findings. Finally, of particular interest to a practicing general dermatology audience, we review concepts of autoinflammation as they apply to understanding the disease pathogenesis of common skin disorders.
authors.affiliation: UCSF Department of Dermatology, University of California, San Francisco, Calif., USA.
authors.forename: Aditi S
authors.initials: AS
authors.lastname: Murthy
authors.forename: Kieron
authors.initials: K
authors.lastname: Leslie
mesh_terms: D000152:Acne Vulgaris / Q000276:immunology; D056587:Cryopyrin-Associated Periodic Syndromes / Q000235:genetics* / Q000276:immunology*; D004485:Eczema / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D058847:Inflammasomes / Q000235:genetics*; D009154:Mutation; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein / Q000235:genetics*; D011565:Psoriasis / Q000276:immunology*; D016463:Sweet Syndrome / Q000276:immunology
chemical_list: D058847:Inflammasomes; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C453881:NLRP3 protein, human