title: Co-opting Innate and Adaptive Immunity against Cancer.
abstract: Researchers at the Massachusetts Institute of Technology in Cambridge have devised a way to completely eradicate large, established tumors in mice. Their four-component strategy comprises a tumor-specific antibody and vaccine, along with IL2 and anti-PD-1 therapy, which employs both innate and adaptive immunity for tumor destruction.
mesh_terms: D056704:Adaptive Immunity; D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D019496:Cancer Vaccines / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006801:Humans; D007113:Immunity, Innate; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D019496:Cancer Vaccines