title: [Epidemic increase in the incidence of carbapenemase-producing Enterobacteriaceae in Denmark].
abstract: Carbapenemase-producing Enterobacteriaceae (CPE) are extremely multiresistant bacteria with few or no treatment options. Infections with CPE are associated with a mortality of 40-50%. In Denmark, CPE were first detected in 2008. Prior to 2013 the CPE incidence was low, but since then the incidence has increased significantly. Seven outbreaks have occurred, and at least 25 patients have been infected or colonized. The rise in CPE incidence emphasizes the need for a national intervention to reduce the spread. This can be obtained through systematic surveillance, infection control and reduction of antibiotic consumption.
authors.affiliation: mikwan@rm.dk.
authors.forename: Mikala
authors.initials: M
authors.lastname: Wang
authors.forename: Svend
authors.initials: S
authors.lastname: Ellermann-Eriksen
authors.forename: Dennis Schrøder
authors.initials: DS
authors.lastname: Hansen
authors.forename: Anne
authors.initials: A
authors.lastname: Kjerulf
authors.forename: David
authors.initials: D
authors.lastname: Fuglsang-Damgaard
authors.forename: Anette
authors.initials: A
authors.lastname: Holm
authors.forename: Claus
authors.initials: C
authors.lastname: Østergaard
authors.forename: Bent
authors.initials: B
authors.lastname: Røder
authors.forename: Ute Wolff
authors.initials: UW
authors.lastname: Sönksen
authors.forename: Mette
authors.initials: M
authors.lastname: Detlefsen
authors.forename: Frank
authors.initials: F
authors.lastname: Hansen
authors.forename: Henrik
authors.initials: H
authors.lastname: Hasman
authors.forename: Anette
authors.initials: A
authors.lastname: Hammerum
authors.forename: Robert L
authors.initials: RL
authors.lastname: Skov
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000073182:Carbapenem-Resistant Enterobacteriaceae / Q000378:metabolism*; D003140:Communicable Disease Control; D003718:Denmark / Q000453:epidemiology; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000201:enzymology*; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000517:prevention & control; D058872:Epidemics; D004926:Escherichia coli / Q000378:metabolism; D006801:Humans; D017053:Infection Control; D007711:Klebsiella pneumoniae / Q000378:metabolism; D000076082:Travel-Related Illness
chemical_list: D000900:Anti-Bacterial Agents