title: Comparison of intraocular pressure andvault after implantation of implantable collamer lens with and without a central hole.
abstract: BACKGROUND
  The Implantable Collamer Lens (ICL) has been used widely for refractive errors, We performed this prospective randomized comparative study to compare postoperative intraocular pressure (IOP) and vaults of the eyes implanted with conventional ICL and central hole ICL.
  
  
  METHODS
  This study evaluated 44 eyes of 22 patients who underwent central hole ICL implantation in one eye and conventional ICL implantation in the other eye by randomization assignment. noncontact intraocular pressure were performed on 6 h, 1 day, 3 days, 1 week, 2 weeks, 1 month, 3 months and 6 months, while ICL vaults were measured on 1 day, 1 week, 1 month and 6 months.
  
  
  RESULTS
  The IOP of both eyeswithcentral hole and conventional ICLrosetemporarily during the first month after surgeries, especially on 1 day and 2 weeks points postoperatively. The IOP ofeyes with central hole ICL was higher than that of conventionl ICL. The vaults ofeyes with central hole and conventional ICL decreased slightly with time but did not significantly affect the postoperative IOP.
  
  
  CONCLUSIONS
  Despite the sensitivity of viscoelastic agents or inflammation, this newly developed central hole ICL implantation appears to be equivalent in safty and effcacy to conventional ICL implantation for the correction of ametropia.
  
  
  BACKGROUND
  Current Controlled Trials ChiCTR-INR-16008896 . Retrospectively registered 24 July 2016.
authors.affiliation: Department of Ophthalmology, Cangzhou CentralHospital, Hebei, China.|Department of Ophthalmology, Second Hospital of Hebei Medical University, Hebei, China.
authors.forename: Haiting
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, Cangzhou CentralHospital, Hebei, China.
authors.forename: Guangzeng
authors.initials: G
authors.lastname: Niu
authors.affiliation: Department of Ophthalmology, Cangzhou CentralHospital, Hebei, China.
authors.forename: Yuxiang
authors.initials: Y
authors.lastname: Fan
authors.affiliation: Department of Ophthalmology, Second Hospital of Hebei Medical University, Hebei, China. majingxue2000@163.com.
authors.forename: Jingxue
authors.initials: J
authors.lastname: Ma
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D059035:Perioperative Period; D054120:Phakic Intraocular Lenses; D011184:Postoperative Period; D011446:Prospective Studies; D014792:Visual Acuity; D055815:Young Adult
keywords: Implantable Collamer Lens; Intraocular Pressure; Vault