title: Metal-catalyzed reductive coupling of olefin-derived nucleophiles: Reinventing carbonyl addition.
abstract: α-Olefins are the most abundant petrochemical feedstock beyond alkanes, yet their use in commodity chemical manufacture is largely focused on polymerization and hydroformylation. The development of byproduct-free catalytic C-C bond-forming reactions that convert olefins to value-added products remains an important objective. Here, we review catalytic intermolecular reductive couplings of unactivated and activated olefin-derived nucleophiles with carbonyl partners. These processes represent an alternative to the longstanding use of stoichiometric organometallic reagents in carbonyl addition.
authors.affiliation: Department of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Khoa D
authors.initials: KD
authors.lastname: Nguyen
authors.affiliation: Department of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Boyoung Y
authors.initials: BY
authors.lastname: Park
authors.affiliation: Department of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Tom
authors.initials: T
authors.lastname: Luong
authors.affiliation: Department of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sato
authors.affiliation: Department of Chemistry, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Victoria J
authors.initials: VJ
authors.lastname: Garza
authors.affiliation: Department of Chemistry, University of Texas at Austin, Austin, TX 78712, USA. mkrische@mail.utexas.edu.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Krische