title: Transcatheter mitral valve replacement: A frontier in cardiac intervention.
abstract: As transcatheter aortic valve replacement (TAVR) has become routine, device manufacturers and investigational cardiologists have set their sights on the mitral valve. Although transcatheter mitral valve replacement (TMVR) poses several technical challenges, they appear to be surmountable, and work is proceeding. Here we review the various devices being developed and preliminary results of trials in humans.
authors.affiliation: Program Director, Interventional Cardiology Fellowship, Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA. E-mail: krishna2@ccf.org.|Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Amar
authors.initials: A
authors.lastname: Krishnaswamy
authors.affiliation: Surgical Director, TAVR, Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Mick
authors.affiliation: Departments of Thoracic and Cardiovascular Surgery, Biomedical Engineering, and Transplantation Center, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Jose
authors.initials: J
authors.lastname: Navia
authors.affiliation: Institute Experience Officer, Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.|Associate Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: A Marc
authors.initials: AM
authors.lastname: Gillinov
authors.affiliation: Chairman, Department of Cardiovascular Medicine, Cleveland Clinic, Abu Dhabi.|Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: E Murat
authors.initials: EM
authors.lastname: Tuzcu
authors.affiliation: Director, Sones Catheterization Laboratories, Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.|Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Samir R
authors.initials: SR
authors.lastname: Kapadia
mesh_terms: D006328:Cardiac Catheterization; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000601:surgery*