title: Isolated Unilateral Hand Weakness Due to Cortical Cerebral Ischemia.
abstract: Isolated hand weakness is a relatively common clinical presentation. The differential diagnoses include peripheral and central neurological lesions. This is a report of sudden onset, pure hand weakness, without any other neurological signs or symptoms in the setting of a prolonged hospital stay for bilateral diabetic foot ulceration. A cerebral magnetic resonance image identified an "inverted omega sign" along the right precentral gyrus and paracentral lobule, consistent with an area of acute cortical infarction. Patients with acute pure hand weakness, and risk factors for cerebral vascular disease, should be carefully evaluated for a cortical lesion in addition to the routine peripheral neurologic workup.
authors.affiliation: Department of Rehabilitation Medicine, Calvary Hospital, 91-111 Rocky Point Road, Kogarah, NSW 2217, Australia(∗). Electronic address: w.qu2010@hotmail.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Qu
authors.affiliation: Department of Rehabilitation Medicine, Calvary Hospital, Kogarah, Australia; University of New South Wales, Kensington, Australia(†).
authors.forename: Matthew
authors.initials: M
authors.lastname: Gardiner
mesh_terms: D000368:Aged; D002544:Cerebral Infarction / Q000150:complications* / Q000000981:diagnostic imaging*; D005260:Female; D059907:Functional Neuroimaging / Q000379:methods; D006225:Hand / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009044:Motor Cortex / Q000098:blood supply; D018908:Muscle Weakness / Q000209:etiology* / Q000503:physiopathology*; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index