title: Basics of Hematopoietic Cell Transplantation for Primary Care Physicians and Internists.
abstract: More than 60,000 hematopoietic cell transplantations (HCTs) are annually performed worldwide to treat a variety of malignant and nonmalignant conditions. Although HCT is complicated and risky, a majority of the HCT recipients are surviving for many years post-transplant. This article presents the basics of transplantation, HCT types/stem cell sources, mobilization and conditioning procedures, indications for HCT, conditioning regimens, engraftment, graft-versus-host-disease, and survivorship issues.
authors.affiliation: Mayo Clinic, Rochester, MN 55901, USA. Electronic address: hashmi.shahrukh@mayo.edu.
authors.forename: Shahrukh Khurshid
authors.initials: SK
authors.lastname: Hashmi
mesh_terms: D006086:Graft vs Host Disease / Q000276:immunology; D006402:Hematologic Diseases / Q000276:immunology* / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D011320:Primary Health Care; D012307:Risk Factors; D019172:Transplantation Conditioning / Q000379:methods; D014181:Transplantation Immunology
keywords: Bone marrow transplant; Engraftment; Graft-versus-host disease; Stem cell transplant