title: Imaging of Hereditary Tumors of the Female Genital System.
abstract: Cancers of the female genital system, particularly endometrial and ovarian cancers, can be associated with hereditary cancer syndromes such as hereditary breast and ovarian cancer and Lynch syndrome. Cancers that are found in the setting of a hereditary cancer syndrome are often unique in presentation, clinical features, and pathologic profiles when compared with sporadic tumors. This article reviews the hereditary cancer syndromes associated with gynecological malignancies, as well as the imaging findings and staging system of endometrial and ovarian cancers. These associations are important for proper patient screening, diagnosis, and treatment.
authors.affiliation: From the *Department of Diagnostic and Interventional Imaging, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX; †Department of Diagnostic Radiology, Mayo Clinic, Scottsdale, AZ; ‡Department of Diagnostic Radiology, The University of Toledo, OH; §Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX; ∥Department of Diagnostic Radiology, University of Utah, Salt Lake City, UT; ¶Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO; and #Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX.
authors.forename: Sarah M
authors.initials: SM
authors.lastname: Rothan
authors.forename: Christine O
authors.initials: CO
authors.lastname: Menias
authors.forename: Yehia M
authors.initials: YM
authors.lastname: ElGuindy
authors.forename: Corey T
authors.initials: CT
authors.lastname: Jensen
authors.forename: Akram M
authors.initials: AM
authors.lastname: Shaaban
authors.forename: Priya
authors.initials: P
authors.lastname: Bhosale
authors.forename: Michelle V
authors.initials: MV
authors.lastname: Lee
authors.forename: Venkata S
authors.initials: VS
authors.lastname: Katabathina
authors.forename: Khaled M
authors.initials: KM
authors.lastname: Elsayes
mesh_terms: D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005833:Genital Neoplasms, Female / Q000000981:diagnostic imaging* / Q000235:genetics*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D013577:Syndrome; D014463:Ultrasonography / Q000379:methods*