title: Palladium-Catalyzed C-H Functionalization of Phenyl 2-Pyridylsulfonates.
abstract: An efficient palladium(II)-catalyzed intermolecular direct ortho-alkenylation and acetoxylation of phenols has been developed. The reaction proceeded via a seven-membered cyclopalladated intermediate and showed complete regio- and diastereoselectivity. The approach also provided an efficient route for the synthesis of coumarins and benzofurans.
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry&Materials Science, Northwest University, Xi'an, 710069, P. R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry&Materials Science, Northwest University, Xi'an, 710069, P. R. China.
authors.forename: Dong-Dong
authors.initials: DD
authors.lastname: Guo
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry&Materials Science, Northwest University, Xi'an, 710069, P. R. China.
authors.forename: Shi-Huan
authors.initials: SH
authors.lastname: Guo
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry&Materials Science, Northwest University, Xi'an, 710069, P. R. China.
authors.forename: Gao-Fei
authors.initials: GF
authors.lastname: Pan
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry&Materials Science, Northwest University, Xi'an, 710069, P. R. China.
authors.forename: Ya-Ru
authors.initials: YR
authors.lastname: Gao
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry&Materials Science, Northwest University, Xi'an, 710069, P. R. China.
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Wang
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001572:Benzofurans; D003374:Coumarins; D010636:Phenols; D011725:Pyridines; D010165:Palladium
keywords: C−H activation; acetoxylation; olefination; phenols; regioselectivity