title: The Oxytocin Receptor Gene ( OXTR) and Face Recognition.
abstract: A recent study has linked individual differences in face recognition to rs237887, a single-nucleotide polymorphism (SNP) of the oxytocin receptor gene ( OXTR; Skuse et al., 2014). In that study, participants were assessed using the Warrington Recognition Memory Test for Faces, but performance on Warrington's test has been shown not to rely purely on face recognition processes. We administered the widely used Cambridge Face Memory Test-a purer test of face recognition-to 370 participants. Performance was not significantly associated with rs237887, with 16 other SNPs of OXTR that we genotyped, or with a further 75 imputed SNPs. We also administered three other tests of face processing (the Mooney Face Test, the Glasgow Face Matching Test, and the Composite Face Test), but performance was never significantly associated with rs237887 or with any of the other genotyped or imputed SNPs, after corrections for multiple testing. In addition, we found no associations between OXTR and Autism-Spectrum Quotient scores.
authors.affiliation: 1 Department of Psychology, University of Cambridge.
authors.forename: Roeland J
authors.initials: RJ
authors.lastname: Verhallen
authors.affiliation: 1 Department of Psychology, University of Cambridge.|2 School of Psychology, University of Sussex.
authors.forename: Jenny M
authors.initials: JM
authors.lastname: Bosten
authors.affiliation: 1 Department of Psychology, University of Cambridge.|3 School of Psychological Sciences, University of Melbourne.
authors.forename: Patrick T
authors.initials: PT
authors.lastname: Goodbourn
authors.affiliation: 1 Department of Psychology, University of Cambridge.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Lawrance-Owen
authors.affiliation: 1 Department of Psychology, University of Cambridge.|4 Division of Optometry and Visual Science, City University London.
authors.forename: Gary
authors.initials: G
authors.lastname: Bargary
authors.affiliation: 1 Department of Psychology, University of Cambridge.
authors.forename: J D
authors.initials: JD
authors.lastname: Mollon
mesh_terms: D000293:Adolescent; D000328:Adult; D000067877:Autism Spectrum Disorder; D005145:Face; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D010121:Oxytocin / Q000235:genetics* / Q000502:physiology; D020641:Polymorphism, Single Nucleotide; D018045:Receptors, Oxytocin / Q000235:genetics*; D021641:Recognition, Psychology / Q000502:physiology*; D012919:Social Behavior; D055815:Young Adult
chemical_list: D018045:Receptors, Oxytocin; D010121:Oxytocin
keywords: Autism-Spectrum Quotient; Cambridge Face Memory Test; OXTR; face recognition; oxytocin receptor gene; rs237887