title: Pubertal height gain is inversely related to peak BMI in childhood.
abstract: Childhood BMI may influence subsequent growth in height as well as the timing of puberty. The aim of the present study was to investigate associations between BMI in childhood and subsequent height gain/pubertal growth.
  
  
  
  Longitudinal growth data were used (GrowUp1990Gothenburg cohort, n = 1,901). The QEPS growth-model was used to characterize height gain in relation to the highest BMISDSvalue between 3.5 and 8 y of age. Children were defined as overweight/obese (OwOb) or normal weight/underweight (NwUw), using the 2012 International Obesity Task Force criteria.
  
  
  
  A negative association between childhood BMISDSand pubertal height gain was observed. Already at birth, OwOb children were heavier than NwUw children, and had a greater height velocity during childhood. Onset of puberty was 3.5/3.0 mo earlier in OwOb girls/boys, and they had 2.3/3.1 cm less pubertal height gain from the QEPS-models specific P-function than NwUw children. Adult height was not related to childhood BMI.
  
  
  
  We found that pubertal height gain was inversely related to peak BMI in childhood. Higher childhood BMISDSwas associated with more growth before onset of puberty, earlier puberty, and less pubertal height gain, resulting in similar adult heights for OwOb and NwUw children.
authors.affiliation: Göteborg Pediatric Growth Research Center (GP-GRC), Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.|Department of Pediatrics, Halmstad Hospital, Halmstad, Sweden.
authors.forename: Anton
authors.initials: A
authors.lastname: Holmgren
authors.affiliation: Göteborg Pediatric Growth Research Center (GP-GRC), Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Aimon
authors.initials: A
authors.lastname: Niklasson
authors.affiliation: Muvara bv, Multivariate Analysis of Research Data, Leiderdorp, The Netherlands.
authors.forename: Andreas F M
authors.initials: AF
authors.lastname: Nierop
authors.affiliation: Göteborg Pediatric Growth Research Center (GP-GRC), Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Lars
authors.initials: L
authors.lastname: Gelander
authors.affiliation: Department of Pediatrics, Halmstad Hospital, Halmstad, Sweden.
authors.forename: A Stefan
authors.initials: AS
authors.lastname: Aronson
authors.affiliation: Department of Food and Nutrition, and Sport Science, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Agneta
authors.initials: A
authors.lastname: Sjöberg
authors.affiliation: Section for Epidemiology and Social Medicine (EPSO), Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Lauren
authors.initials: L
authors.lastname: Lissner
authors.affiliation: Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Kerstin
authors.initials: K
authors.lastname: Albertsson-Wikland
mesh_terms: D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009765:Obesity / Q000628:therapy; D050177:Overweight / Q000175:diagnosis; D063766:Pediatric Obesity / Q000175:diagnosis; D011627:Puberty; D012737:Sex Factors; D012741:Sexual Maturation; D013851:Thinness / Q000175:diagnosis