title: Tailored Duration of Contrast Material Injection in High-Pitch Computed Tomographic Aortography With a Double-Level Test Bolus Method.
abstract: To achieve the efficient usage of contrast material (CM) in high-pitch CT aortography, an appropriate duration of the CM injection is crucial. We used a modification of the double-level test bolus method for determination of proper injection duration with the aim of evaluating the image quality of tailored-duration CM injection compared with that of a fixed duration.
  
  
  
  The institutional review board approved retrospective review of 80 consecutive subjects who had undergone high-pitch 70-kVp CT aortography with a modified double-level test bolus method. The interval between peak enhancement at the aortic root and femoral artery was derived from the time/attenuation curves. A total of 40 subjects underwent CT aortography with individually set duration time from the results. The remaining subjects underwent CT aortography with a fixed-duration time. The density values at several parts of the aorta were assessed. The differences in image quality and CM amount used for each method were assessed by Welch test.
  
  
  
  The injection duration was almost 50% shorter (median, 15 seconds; range, 11-25 seconds) when individually tailored. The mean CM amount was reduced by 50% (46.2-23.9 mL, P < 0.01). The range of mean CT attenuation throughout the aorta was not significantly different between the 2 methods (316-327 HU and 305-321 HU, P > 0.05, respectively).
  
  
  
  The modified double-level test bolus method in high-pitch CT aortography can significantly reduce the amount of CM without adversely affecting image quality.
authors.affiliation: From the *Department of Radiology, and †Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nishii
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Shimoyama
authors.forename: Atsushi K
authors.initials: AK
authors.lastname: Kono
authors.forename: Keitaro
authors.initials: K
authors.lastname: Sofue
authors.forename: Shumpei
authors.initials: S
authors.lastname: Mori
authors.forename: Satoru
authors.initials: S
authors.lastname: Takahashi
authors.forename: Kazuro
authors.initials: K
authors.lastname: Sugimura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001027:Aortography / Q000379:methods; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007479:Iopamidol / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011856:Radiographic Image Enhancement / Q000379:methods*; D012189:Retrospective Studies; D012965:Sodium Chloride / Q000008:administration & dosage; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D012965:Sodium Chloride; D007479:Iopamidol