title: Crystal structure of 5-butyl-amino-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde obtained from a microwave-assisted reaction using caesium carbonate as catalyst.
abstract: The title compound, C14H18N4O, synthesized from an unconventional microwave-assisted method using caesium carbonate as catalyst, has an approximately planar conformation with the pyridyl and pyrazole rings inclined by a dihedral angle of 7.94 (3)°, allowing the formation of an intra-molecular N-H⋯N hydrogen bond. The supra-molecular assembly has a three-dimensional arrangement controlled mainly by weak C-H⋯O and C-H⋯π inter-actions.
authors.affiliation: Department of Chemistry, Universidad de los Andes, Carrera 1 No. 18A 10, Bogotá, Colombia.
authors.forename: Mario A
authors.initials: MA
authors.lastname: Macías
authors.affiliation: Bioorganic Compounds Research Group, Department of Chemistry, Universidad de los Andes, Carrera 1 No. 18A 10, Bogotá, Colombia.
authors.forename: Jessica
authors.initials: J
authors.lastname: Orrego-Hernández
authors.affiliation: Bioorganic Compounds Research Group, Department of Chemistry, Universidad de los Andes, Carrera 1 No. 18A 10, Bogotá, Colombia.
authors.forename: Jaime
authors.initials: J
authors.lastname: Portilla
keywords: 5-amino­pyrazoles; crystal structure; hydrogen bonding; nucleophilic substitution; pharmaceutical compound