title: Poor Feeding and Severe Sedation in a Newborn Nursed by a Mother on a Low Dose of Amitriptyline.
abstract: Sleep problems are frequently seen during the postpartum period. Some mothers need to use sedative agents for insomnia. Amitriptyline is a tricyclic antidepressant that has sedative effects. Despite no adverse reports, data on safety for the maternal use of this medication on breastfed infants are limited. This case report presents severe sedation and poor feeding in the breastfed baby of a woman using amitriptyline at 10 mg/day.
authors.affiliation: Department of Psychiatry, Meram Faculty of Medicine, Necmettin Erbakan University , Konya, Turkey .
authors.forename: Faruk
authors.initials: F
authors.lastname: Uguz
mesh_terms: D000328:Adult; D000639:Amitriptyline / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics*; D000928:Antidepressive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics*; D001942:Breast Feeding / Q000009:adverse effects*; D019052:Depression, Postpartum / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D018730:Infant Behavior / Q000187:drug effects*; D007231:Infant, Newborn; D008895:Milk, Human / Q000737:chemistry*; D049590:Postpartum Period / Q000523:psychology*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy; D016896:Treatment Outcome; D014421:Turkey
chemical_list: D000928:Antidepressive Agents; D006993:Hypnotics and Sedatives; D000639:Amitriptyline
keywords: antidepressants; breastfeeding; lactation