title: Rhizopus stolonifer mediated biosynthesis of biocompatible cadmium chalcogenide quantum dots.
abstract: We report an efficient method to biosynthesize biocompatible cadmium telluride and cadmium sulphide quantum dots from the fungus Rhizopus stolonifer. The suspension of the quantum dots exhibited purple and greenish-blue luminescence respectively upon UV light illumination. Photoluminescence spectroscopy, X-ray diffraction, and transmission electron microscopy confirms the formation of the quantum dots. From the photoluminescence spectrum the emission maxima is found to be 424 and 476nm respectively. The X-ray diffraction of the quantum dots matches with results reported in literature. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay for cell viability evaluation carried out on 3-days transfer, inoculum 3×105cells, embryonic fibroblast cells lines shows that more than 80% of the cells are viable even after 48h, indicating the biocompatible nature of the quantum dots. A good contrast in imaging has been obtained upon incorporating the quantum dots in human breast adenocarcinoma Michigan Cancer Foundation-7 cell lines.
authors.affiliation: Department of Electronics and Communication Engineering, G.K.M. College of Engineering and Technology, Chennai 600 063, Tamil Nadu, India.
authors.forename: P
authors.initials: P
authors.lastname: Mareeswari
authors.affiliation: Centre for Nanoscience and Nanotechnology, Sathyabama University, Chennai 600 119, Tamil Nadu, India. Electronic address: brijitta@live.com.
authors.forename: J
authors.initials: J
authors.lastname: Brijitta
authors.affiliation: Department of Physics, G.K.M. College of Engineering and Technology, Chennai 600 063, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Harikrishna Etti
authors.affiliation: Department of Physics, G.K.M. College of Engineering and Technology, Chennai 600 063, Tamil Nadu, India.
authors.forename: C
authors.initials: C
authors.lastname: Meganathan
authors.affiliation: Centre for Nanoscience and Nanotechnology, Sathyabama University, Chennai 600 119, Tamil Nadu, India.
authors.forename: Gobi Saravanan
authors.initials: GS
authors.lastname: Kaliaraj
mesh_terms: D000818:Animals; D001709:Biotechnology; D019187:Cadmium Compounds / Q000737:chemistry* / Q000378:metabolism*; D018011:Chalcogens / Q000737:chemistry* / Q000378:metabolism*; D055772:Green Chemistry Technology; D006801:Humans; D061986:MCF-7 Cells; D051379:Mice; D041681:NIH 3T3 Cells; D036103:Nanotechnology; D045663:Quantum Dots / Q000737:chemistry* / Q000378:metabolism* / Q000648:ultrastructure; D012233:Rhizopus / Q000378:metabolism*; D013440:Sulfides / Q000737:chemistry / Q000378:metabolism; D013691:Tellurium / Q000737:chemistry / Q000378:metabolism
chemical_list: D019187:Cadmium Compounds; D018011:Chalcogens; D013440:Sulfides; C034939:cadmium sulfide; D013691:Tellurium; C028337:cadmium telluride
keywords: Biosynthesis; Cytotoxicity; Photoluminescence; Quantum dots; XRD