title: The third annual BRDS on research and development of nucleic acid-based nanomedicines.
abstract: The completion of human genome project, decrease in the sequencing cost, and correlation of genome sequencing data with specific diseases led to the exponential rise in the nucleic acid-based therapeutic approaches. In the third annual Biopharmaceutical Research and Development Symposium (BRDS) held at the Center for Drug Discovery and Lozier Center for Pharmacy Sciences and Education at the University of Nebraska Medical Center (UNMC), we highlighted the remarkable features of the nucleic acid-based nanomedicines, their significance, NIH funding opportunities on nanomedicines and gene therapy research, challenges and opportunities in the clinical translation of nucleic acids into therapeutics, and the role of intellectual property (IP) in drug discovery and development.
authors.affiliation: Department of Pharmaceutical Sciences, 986025 Nebraska Medical Center, University of Nebraska Medical Center (UNMC), Omaha, NE, 68198-6025, USA.
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Chaudhary
authors.affiliation: Department of Pharmaceutical Sciences, 986025 Nebraska Medical Center, University of Nebraska Medical Center (UNMC), Omaha, NE, 68198-6025, USA. ram.mahato@unmc.edu.
authors.forename: Ram I
authors.initials: RI
authors.lastname: Mahato
mesh_terms: D000818:Animals; D035843:Biomedical Research; D006801:Humans; D050997:Nanomedicine; D009696:Nucleic Acids / Q000627:therapeutic use*
chemical_list: D009696:Nucleic Acids
keywords: Drug delivery; Gene medicine; Nanomedicines; Non-coding RNAs