title: Comparison of rabbit rib defect regeneration with and without graft.
abstract: Rib segment, as one of the most widely used autologous boneresources for bone repair, is commonly isolated with an empty left in the defect. Although defective rib repair is thought to be unnecessary traditionally, it's of vital importance actually to promote rib regeneration for patients with better postoperative recovery and higher life quality. Comparative investigations on rabbit rib bone regeneration with and without graft were reported in this article. A segmental defect was performed on the 8th rib of 4-month-old male New Zealand rabbits. The mineralized collagen bone graft (MC) was implanted into the defect and evaluated for up to 12 weeks. The rib bone repair was investigated by using X-ray at 4, 8 and 12 weeks and histological examinations at 12 weeks after surgery, which showed a higher bone remodeling activity in the groups with MC implantation in comparison with blank control group, especially at the early stage of remodeling.
authors.affiliation: Liaocheng People's Hospital, Medical College of Liaocheng University, ShanDong, 252000, China.|State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China.
authors.forename: Feng-Zhen
authors.initials: FZ
authors.lastname: Liu
authors.affiliation: Liaocheng People's Hospital, Medical College of Liaocheng University, ShanDong, 252000, China.
authors.forename: Da-Wei
authors.initials: DW
authors.lastname: Wang
authors.affiliation: Liaocheng People's Hospital, Medical College of Liaocheng University, ShanDong, 252000, China.
authors.forename: Yu-Jue
authors.initials: YJ
authors.lastname: Zhang
authors.affiliation: Liaocheng People's Hospital, Medical College of Liaocheng University, ShanDong, 252000, China.
authors.forename: Zhao Yong
authors.initials: ZY
authors.lastname: Lv
authors.affiliation: State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China.
authors.forename: Xiao-Dan
authors.initials: XD
authors.lastname: Sun
authors.affiliation: Liaocheng People's Hospital, Medical College of Liaocheng University, ShanDong, 252000, China.
authors.forename: Ke-Yi
authors.initials: KY
authors.lastname: Li
authors.affiliation: Liaocheng People's Hospital, Medical College of Liaocheng University, ShanDong, 252000, China. lcrmyy@163.com.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China. wxm@tsinghua.edu.cn.
authors.forename: Xiu-Mei
authors.initials: XM
authors.lastname: Wang
authors.affiliation: State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China.
authors.forename: Fu-Zhai
authors.initials: FZ
authors.lastname: Cui
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D016723:Bone Remodeling; D018786:Bone Substitutes; D016025:Bone Transplantation / Q000379:methods*; D002113:Calcification, Physiologic; D003094:Collagen; D008297:Male; D011817:Rabbits; D012272:Ribs / Q000293:injuries / Q000601:surgery*; D054457:Tissue Scaffolds; D014945:Wound Healing
chemical_list: D018786:Bone Substitutes; D003094:Collagen