title: Human papillomavirus vaccines, complex regional pain syndrome, postural orthostatic tachycardia syndrome, and autonomic dysfunction - a review of the regulatory evidence from the European Medicines Agency.
abstract: Recent concerns about a possible association between exposure of young women to human papillomavirus (HPV) vaccines and two "dysautonomic syndromes" (a collection of signs and symptoms thought to be caused by autoimmunity) - complex regional pain syndrome (CRPS) and postural orthostatic tachycardia syndrome (POTS) - led the European Medicines Agency (EMA) to review existing evidence. The review was announced by the EMA on July 13, 2015, and was completed on November 4, 2015.
authors.affiliation: Honorary Research Fellow, Centre for Evidence Based Medicine, Oxford OX2 6GG, UK,. jefferson.tom@gmail.com.
authors.forename: Tom
authors.initials: T
authors.lastname: Jefferson
authors.affiliation: The Nordic Cochrane Centre, Rigshospitalet 7811, Blegdamsvej 9, 2100 Copenhagen, Denmark,. larsjorgensens@gmail.com.
authors.forename: Lars
authors.initials: L
authors.lastname: Jørgensen
mesh_terms: D020918:Complex Regional Pain Syndromes; D005260:Female; D006801:Humans; D007194:India; D053918:Papillomavirus Vaccines; D054972:Postural Orthostatic Tachycardia Syndrome
chemical_list: D053918:Papillomavirus Vaccines