title: A First Evaluation of OMNI®, A New Device for Continuous Renal Replacement Therapy.
abstract: BACKGROUND
  Omni® (B. Braun, Germany) is a new-generation, continuous renal replacement therapy (CRRT) machine designed to improve user interface, minimize downtime and optimize renal dose delivery. It was never tested in humans.
  
  
  METHODS
  We used Omni® to provide CRRT in 10 critically ill patients. We collected therapy data, metabolic parameters and evaluated user's satisfaction with a survey.
  
  
  RESULTS
  CRRT was delivered using Omni® in CVVH-heparin (6 patients) and CVVHD-citrate (4 patients) modes for a total duration of 617.7 h. No adverse event was observed. The mean filter life was 22.8 (CVVH-heparin) and 33.5 (CVVHD-citrate) h. Alarms-related downtime corresponded to 5.9% of total therapy time. Delivered renal dose was 96.6% of prescribed. Satisfactory metabolic control and fluid removal were achieved. Overall, users evaluated interface, design and usability as excellent.
  
  
  CONCLUSIONS
  CRRT in CVVH-heparin and CVVHD-citrate modes was provided using Omni® in a safe and efficient way for 10 critically ill patients. Video Journal Club 'Cappuccino with Claudio Ronco' at http://www.karger.com/?doi=451053.
authors.affiliation: Adult Intensive Care Unit, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
authors.forename: Pierre
authors.initials: P
authors.lastname: Schläpfer
authors.forename: Jean-Daniel
authors.initials: JD
authors.lastname: Durovray
authors.forename: Valery
authors.initials: V
authors.lastname: Plouhinec
authors.forename: Cristiano
authors.initials: C
authors.lastname: Chiappa
authors.forename: Rinaldo
authors.initials: R
authors.lastname: Bellomo
authors.forename: Antoine
authors.initials: A
authors.lastname: Schneider
mesh_terms: D019343:Citric Acid / Q000627:therapeutic use; D016638:Critical Illness; D004867:Equipment Design; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D061214:Patient Safety; D017582:Renal Replacement Therapy / Q000295:instrumentation*; D013997:Time Factors
chemical_list: D019343:Citric Acid; D006493:Heparin