title: Modelling gas exchange during platelet storage without agitation.
abstract: The aim of this study was to create a model of oxygen distribution within platelet storage bags to evaluate implications of reduced agitation approaches. Based on our model, platelet concentration and surface area most affect internal partial pressure of oxygen, while temperature modifications have least effect, indicating primary potential approaches for optimization of platelet storage with reduced or absent agitation.
authors.affiliation: Pathology and Laboratory Medicine Service, VA Connecticut Healthcare System, West Haven, CT, USA.|Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: R
authors.initials: R
authors.lastname: Torres
authors.affiliation: Pathology and Laboratory Medicine Service, VA Connecticut Healthcare System, West Haven, CT, USA.|Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Tormey
mesh_terms: D001792:Blood Platelets / Q000502:physiology; D001793:Blood Preservation / Q000295:instrumentation / Q000379:methods*; D002245:Carbon Dioxide / Q000097:blood; D006801:Humans; D010100:Oxygen / Q000097:blood; D010539:Permeability
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen
keywords: platelet concentrates; platelet function; quality control