title: Post-donation telephonic interview of blood donors providing an insight into delayed adverse reactions: First attempt in India.
abstract: BACKGROUND
  Blood donor experiences both immediate adverse reactions (IAR) and delayed adverse reactions (DAR). With limited published data available on the incidence of DAR, a study was conducted to estimate incidence and profile of DAR through telephonic interview.
  
  
  METHODS
  Study was conducted over a 45-day period for consecutive volunteer whole blood donations at tertiary care hospital. Donors were divided into first-time, repeat and regular and were monitored for IAR. They were given written copy of post-donation advice. Donors were contacted telephonically three weeks post-donation and enquired about general wellbeing and specific DAR in accordance with a standard n international (International Society of Blood Transfusion) standard format.
  
  
  RESULTS
  Donors participated in the study of which 1.6% donors experienced an IAR. Much larger number reported DAR (10.3% vs.1.6% p<0.0001). Further, DAR was presented as a variegated profile with bruise, painful arms and fatigue being the commonest. DARs were more common in females than males (25% vs. 10.3%, p<0.02). Localized DAR like bruise and painful arms were more common in younger donors (age <50 years) whereas systemic DAR like fatigue was common in older donors (>50 years). First time (12.3%) and repeat donors (13.5%) had similar frequency of DAR but were lower among regular donors (6.7%).
  
  
  CONCLUSIONS
  DARs are more common than IAR and are of different profile. Post-donation interview has provided an insight into donor experiences and can be used as a valuable tool in donor hemovigilance.
authors.affiliation: Department of Transfusion Medicine, Medanta-The Medicity, Sector-38, Gurgaon 122001, India. Electronic address: aseemtwr@yahoo.co.in.
authors.forename: Aseem K
authors.initials: AK
authors.lastname: Tiwari
authors.affiliation: Department of Transfusion Medicine, Medanta-The Medicity, Sector-38, Gurgaon 122001, India.
authors.forename: Geet
authors.initials: G
authors.lastname: Aggarwal
authors.affiliation: Department of Transfusion Medicine, Medanta-The Medicity, Sector-38, Gurgaon 122001, India.
authors.forename: Ravi C
authors.initials: RC
authors.lastname: Dara
authors.affiliation: Department of Transfusion Medicine, Medanta-The Medicity, Sector-38, Gurgaon 122001, India.
authors.forename: Dinesh
authors.initials: D
authors.lastname: Arora
authors.affiliation: Department of Transfusion Medicine, Medanta-The Medicity, Sector-38, Gurgaon 122001, India.
authors.forename: Khushboo
authors.initials: K
authors.lastname: Srivastava
authors.affiliation: Laboratory Services and Transfusion Medicine, Medanta-The Medicity, Sector-38, Gurgaon 122001, India.
authors.forename: Vimarsh
authors.initials: V
authors.lastname: Raina
mesh_terms: D000328:Adult; D001782:Blood Donors; D005260:Female; D006801:Humans; D007194:India; D007407:Interviews as Topic; D008297:Male; D011446:Prospective Studies; D011795:Surveys and Questionnaires
keywords: Adverse reaction; Delayed adverse reaction (DAR); Immediate adverse reaction (IAR); Telephonic interview