title: Recent Nanotechnology Approaches for Prevention and Treatment of Biofilm-Associated Infections on Medical Devices.
abstract: Bacterial colonization in the form of biofilms on surfaces causes persistent infections and is an issue of considerable concern to healthcare providers. There is an urgent need for novel antimicrobial or antibiofilm surfaces and biomedical devices that provide protection against biofilm formation and planktonic pathogens, including antibiotic resistant strains. In this context, recent developments in the material science and engineering fields and steady progress in the nanotechnology field have created opportunities to design new biomaterials and surfaces with anti-infective, antifouling, bactericidal, and antibiofilm properties. Here we review a number of the recently developed nanotechnology-based biomaterials and explain underlying strategies used to make antibiofilm surfaces.
authors.affiliation: School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
authors.forename: Mohankandhasamy
authors.identifier: 0000-0002-8136-5903
authors.initials: M
authors.lastname: Ramasamy
authors.affiliation: School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
authors.forename: Jintae
authors.identifier: 0000-0003-1383-1682
authors.initials: J
authors.lastname: Lee
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage; D001672:Biocompatible Materials / Q000008:administration & dosage*; D018441:Biofilms / Q000254:growth & development*; D017714:Community-Acquired Infections / Q000517:prevention & control*; D004864:Equipment and Supplies / Q000382:microbiology*; D006282:Health Personnel; D006801:Humans; D017053:Infection Control / Q000379:methods*; D036103:Nanotechnology / Q000379:methods*; D013499:Surface Properties
chemical_list: D000890:Anti-Infective Agents; D001672:Biocompatible Materials