title: Two years' experience of using the Bravo wireless oesophageal pH monitoring system at a single UK tertiary centre.
abstract: OBJECTIVE
  The Bravo wireless pH monitoring system enables oesophageal pH to be monitored in children intolerant to nasal catheters and records measurements over 48 hours. This study aimed to document the minimum child weight that enabled successful capsule placement and any associated complications. We also compared the diagnostic sensitivity of 48 hours versus 24 hours.
  
  
  METHODS
  We included 203 consecutive patients (122 male children) with clinically documented or suspected reflux symptoms. The age range was two years to 19 years, and the minimum weight was 9.29 kg. The pH capsule was deployed endoscopically under general anaesthetic. Recordings taken over 24 and 48 hours were compared to determine the frequency of differences and correlations in the reflux index and DeMeester scores.
  
  
  RESULTS
  Testing using the detached probe was successful in 190 children (93.6%) with weight as low as 9.29 kg, with no side effects, with failed deployment being the most frequent problem. Clinically different results in the reflux index were found in 16% of the children's day 1 or day 2 readings (p < 0.0001), suggesting the benefit of 48-hour measurements.
  
  
  CONCLUSIONS
  Measuring oesophageal pH with the Bravo wireless pH monitoring system was successful in 93.6% of cases. A 48-hour test improved the detection rate of gastro-oesophageal reflux disease by 16%.
authors.affiliation: Centre for Paediatric Gastroenterology, Hepatology and Nutrition, Sheffield Children's Hospital, Sheffield, UK.
authors.forename: Nagendra M
authors.initials: NM
authors.lastname: Rao
authors.affiliation: Centre for Paediatric Gastroenterology, Hepatology and Nutrition, Sheffield Children's Hospital, Sheffield, UK.
authors.forename: David I
authors.initials: DI
authors.lastname: Campbell
authors.affiliation: Centre for Paediatric Gastroenterology, Hepatology and Nutrition, Sheffield Children's Hospital, Sheffield, UK.
authors.forename: Prithviraj
authors.initials: P
authors.lastname: Rao
mesh_terms: D000293:Adolescent; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D050782:Esophageal pH Monitoring / Q000295:instrumentation*; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013997:Time Factors; D059015:Wireless Technology; D055815:Young Adult
keywords: DeMeester score; Gastro-oesophageal reflux disease; Nasal catheter intolerance; Reflux index; Wireless pH monitoring