title: The in vitro mechanisms of isoniazid and ethionamide resistance poorly reflect those in vivo in Mycobacterium tuberculosis.
authors.affiliation: National Reference Center for Mycobacteria and Antimycobacterial Resistance, Paris, France; AP-HP, Hôpital Pitié-Salpêtrière, Laboratory of Bacteriology, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMRS1135, CIMI-Paris, team 13, Paris, France. Electronic address: florence.brossier@aphp.fr.
authors.forename: Florence
authors.initials: F
authors.lastname: Brossier
authors.affiliation: National Reference Center for Mycobacteria and Antimycobacterial Resistance, Paris, France; AP-HP, Hôpital Lariboisière, Laboratory of Bacteriology, Paris, France; Univ Paris Diderot, IAME UMR1137, Sorbonne Paris Cité, Paris, France.
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Cambau
authors.affiliation: National Reference Center for Mycobacteria and Antimycobacterial Resistance, Paris, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Tessier
authors.affiliation: National Reference Center for Mycobacteria and Antimycobacterial Resistance, Paris, France; AP-HP, Hôpital Pitié-Salpêtrière, Laboratory of Bacteriology, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMRS1135, CIMI-Paris, team 13, Paris, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Jarlier
authors.affiliation: National Reference Center for Mycobacteria and Antimycobacterial Resistance, Paris, France; AP-HP, Hôpital Pitié-Salpêtrière, Laboratory of Bacteriology, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMRS1135, CIMI-Paris, team 13, Paris, France.
authors.forename: Wladimir
authors.initials: W
authors.lastname: Sougakoff
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics*; D002374:Catalase / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D005000:Ethionamide / Q000494:pharmacology*; D005838:Genotype; D007538:Isoniazid / Q000494:pharmacology*; D009154:Mutation; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000235:genetics*; D010088:Oxidoreductases / Q000235:genetics; D010641:Phenotype; D011401:Promoter Regions, Genetic; D012097:Repressor Proteins / Q000235:genetics
chemical_list: D000995:Antitubercular Agents; D001426:Bacterial Proteins; C481661:EthR protein, Mycobacterium tuberculosis; D012097:Repressor Proteins; D010088:Oxidoreductases; D002374:Catalase; C480353:katG protein, Mycobacterium tuberculosis; C085257:InhA protein, Mycobacterium; C480352:ethA protein, Mycobacterium tuberculosis; D005000:Ethionamide; D007538:Isoniazid