title: Cardiac function and survival are affected by crude oil in larval red drum, Sciaenops ocellatus.
abstract: Following exposure to weathered and non-weathered oil, lethal and sub-lethal impacts on red drum larvae were assessed using survival, morphological, and cardiotoxicity assays. The LC50 for red drum ranged from 14.6 (10.3-20.9) to 21.3 (19.1-23.8) μgl-1ΣPAH with no effect of exposure timing during the pre-hatch window or oil weathering. Similarly, morphological deformities showed dose responses in the low ppb range. Cardiac output showed similar sensitivity resulting in a major 70% reduction after exposure to 2.6μgl-1ΣPAH. This cardiac failure was driven by reduced stroke volume rather than bradycardia, meaning that in some species, cardiac function is more sensitive than previously thought. After the Deepwater Horizon oil spill, much of this type of work has primarily focused on pelagic species with little known about fast developing estuarine species. These results demonstrate similarity sensitivity of the red drum as their pelagic counter parts, and more importantly, that cardiac function is dramatically reduced in concert with pericardial edema.
authors.affiliation: University of Texas at Austin, Marine Science Institute, 750 Channel View Drive, Port Aransas, TX 78373, USA. Electronic address: akhursigara@utexas.edu.
authors.forename: Alexis J
authors.initials: AJ
authors.lastname: Khursigara
authors.affiliation: University of North Texas, Department of Biological Sciences, 1155 Union Cir, Denton, TX 76203, USA.
authors.forename: Prescilla
authors.initials: P
authors.lastname: Perrichon
authors.affiliation: University of North Texas, Department of Biological Sciences, 1155 Union Cir, Denton, TX 76203, USA.
authors.forename: Naim
authors.initials: N
authors.lastname: Martinez Bautista
authors.affiliation: University of North Texas, Department of Biological Sciences, 1155 Union Cir, Denton, TX 76203, USA.
authors.forename: Warren W
authors.initials: WW
authors.lastname: Burggren
authors.affiliation: University of Texas at Austin, Marine Science Institute, 750 Channel View Drive, Port Aransas, TX 78373, USA.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Esbaugh
mesh_terms: D000818:Animals; D004784:Environmental Monitoring; D006321:Heart / Q000187:drug effects*; D010473:Perciformes / Q000502:physiology*; D010578:Petroleum / Q000633:toxicity*; D059392:Petroleum Pollution; D011084:Polycyclic Aromatic Hydrocarbons; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons; D014874:Water Pollutants, Chemical
keywords: Cardiac function; Deepwater Horizon; Polycyclic aromatic hydrocarbons (PAHS); Weathering