title: Continuous Positive Airway Pressure Strategies with Bubble Nasal Continuous Positive Airway Pressure: Not All Bubbling Is the Same: The Seattle Positive Airway Pressure System.
abstract: Premature neonates are predisposed to complications, including bronchopulmonary dysplasia (BPD). BPD is associated with long-term pulmonary and neurodevelopmental consequences. Noninvasive respiratory support with nasal continuous positive airway pressure (CPAP) has been recommended strongly by the American Academy of Pediatrics. However, CPAP implementation has shown at least a 50% failure rate. Enhancing nasal CPAP effectiveness may decrease the need for mechanical ventilation and reduce the incidence of BPD. Bubble nasal CPAP is better than nasal CPAP using mechanical devices and the bubbling provides air exchange in distal respiratory units. The Seattle PAP system reduces parameters that assess work of breathing.
authors.affiliation: Department of Pediatrics, Baylor College of Medicine, 6621 Fannin Street, W1604, Houston, TX 77030, USA. Electronic address: welty@bcm.edu.
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Welty
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000453:epidemiology; D045422:Continuous Positive Airway Pressure / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D017211:Treatment Failure
keywords: Bronchopulmonary dysplasia; Bubbling; CPAP; Continuous positive airway pressure; Premature infant; Seattle PAP system