title: Quality of Life Changes Following Concurrent Septoplasty and/or Inferior Turbinoplasty During Endoscopic Pituitary Surgery.
abstract: OBJECTIVE
  Endoscopic endonasal transsphenoidal surgery (EETS) is a widely accepted technique for sellar tumors. Common findings during preoperative assessment include septal deviations and turbinate hypertrophy. This study evaluated quality of life changes after concurrent septoplasty and/or inferior turbinoplasty during EETS.
  
  
  METHODS
  A retrospective review was performed of a prospectively collected database including all patients undergoing EETS at our institution during a 10-month period between 2015 and 2016. Patients were divided into a septoplasty/inferior turbinoplasty group and a no septoplasty/inferior turbinoplasty group. The Sino-Nasal Outcome Test (SNOT-22) was used to evaluate quality of life. Mean preoperative scores were compared with 1- and 3-month postoperative scores within each cohort. The SNOT-22 was also reorganized into 5 distinct subdomains. Average subdomain scores were calculated, and preoperative and 1- and 3-month postoperative subdomain scores were compared within each cohort. A paired Student t test was used. P values < 0.05 were considered statistically significant.
  
  
  RESULTS
  All 24 patients met inclusion criteria by completing preoperative and postoperative SNOT-22 surveys. In the septoplasty/inferior turbinoplasty group, preoperative and 3-month postoperative scores showed a clinically significant difference (P = 0.047). The septoplasty/inferior turbinoplasty group specifically showed a significant difference in the psychiatric and sleep SNOT-22 subdomains when comparing preoperative with 3-month postoperative scores (P = 0.03, P = 0.01).
  
  
  CONCLUSIONS
  Patients who underwent concurrent septoplasty and/or turbinoplasty with EETS had a significantly improved quality of life compared with preoperative assessment, specifically regarding psychological and sleep symptoms.
authors.affiliation: Albany Medical College, Albany, New York, USA.
authors.forename: Daniel D
authors.initials: DD
authors.lastname: Lee
authors.affiliation: Department of Neurosurgery, Albany Medical Center, Albany, New York, USA.
authors.forename: Maria
authors.initials: M
authors.lastname: Peris-Celda
authors.affiliation: Division of Otolaryngology/Head and Neck Surgery, Department of Surgery, Albany Medical Center, Albany, New York, USA.
authors.forename: Anna
authors.initials: A
authors.lastname: Butrymowicz
authors.affiliation: Department of Neurosurgery, Albany Medical Center, Albany, New York, USA.
authors.forename: Tyler
authors.initials: T
authors.lastname: Kenning
authors.affiliation: Division of Otolaryngology/Head and Neck Surgery, Department of Surgery, Albany Medical Center, Albany, New York, USA. Electronic address: pinheic@mail.amc.edu.
authors.forename: Carlos D
authors.initials: CD
authors.lastname: Pinheiro-Neto
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000000981:diagnostic imaging / Q000601:surgery; D009300:Nasal Septum / Q000000981:diagnostic imaging / Q000601:surgery*; D044583:Neuroendoscopy / Q000379:methods / Q000639:trends*; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D011446:Prospective Studies; D011788:Quality of Life; D012189:Retrospective Studies; D012225:Rhinoplasty / Q000379:methods / Q000639:trends*; D013101:Sphenoid Sinus / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome
keywords: Endoscopic pituitary surgery; Quality of life; SNOT-22; Septoplasty; Turbinoplasty