title: Definitive Chemoradiotherapy for Advanced Pulmonary Sarcomatoid Carcinoma.
abstract: Pulmonary sarcomatoid carcinoma is a rare subtype of non-small cell lung cancer with a poor prognosis. We herein report on a case of pulmonary sarcomatoid carcinoma that was treated successfully by concurrent chemoradiotherapy. A 65-year-old man was diagnosed to have pulmonary pleomorphic carcinoma (clinical T4N2M0 stage IIIB). He received concurrent chemoradiotherapy (60 Gy of radiotherapy in 30 fractionations and two courses of chemotherapy with carboplatin and paclitaxel). After chemoradiotherapy, a significant reduction of the tumor size was observed. Two courses of adjuvant chemotherapy were performed. He is currently alive at 15 months after the first treatment without any recurrence or metastasis.
authors.affiliation: Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Japan.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Takeda
authors.forename: Haruo
authors.initials: H
authors.lastname: Matsushita
authors.forename: Masaki
authors.initials: M
authors.lastname: Kubozono
authors.forename: Takaya
authors.initials: T
authors.lastname: Tanabe
authors.forename: Yojiro
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Takaya
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Maiko
authors.initials: M
authors.lastname: Kozumi
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Takahashi
authors.forename: Yu
authors.initials: Y
authors.lastname: Katagiri
authors.forename: Shun
authors.initials: S
authors.lastname: Tasaka
authors.forename: Katsuya
authors.initials: K
authors.lastname: Fukui
authors.forename: Ken
authors.initials: K
authors.lastname: Takeda
authors.forename: Fumiyoshi
authors.initials: F
authors.lastname: Fujishima
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ichinose
authors.forename: Keiichi
authors.initials: K
authors.lastname: Jingu
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D016190:Carboplatin / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000628:therapy*; D059248:Chemoradiotherapy; D017024:Chemotherapy, Adjuvant; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D009367:Neoplasm Staging; D017239:Paclitaxel / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin; D017239:Paclitaxel