title: How far do stabilometric and clinical parameters correlate in peripheral neuropathies?
abstract: Peripheral neuropathies are characterized by the impairment of motor and sensitive nervous fibers. We aimed to investigate the correlation between proprioception, force and the limits of equilibrium parameter (LOE), by assessing 38 patients diagnosed with characterized bilateral neuropathy and 11 healthy subjects. Clinical evaluation, based on a motor and pallesthesic score, enabled their classification into groups corresponding to motor, sensitive or mixed neuropathies. Balance measures on a stabilometric platform allowed differentiation between the patients and healthy subjects but not between the groups of patients. The parameter limits of equilibrium (LOE) calculated as percentage of foot length allowed not only the differentiation between patients and healthy subjects but also between patients showing motor and sensitive forms. ROC analysis gave a threshold of 15% for LOE to discriminate between motor and sensory neuropathies with a 75% of sensitivity and 72% of specificity. Consequently, we propose a simple experimental procedure to carry out an accurate assessment of balance disorders in order to identify future rehabilitation modalities recommended to these patients.
authors.affiliation: CIAMS, Univ. Paris-Sud, Université Paris-Saclay, 91405 Orsay Cedex France. Electronic address: gpaiva.ana@gmail.com.
authors.forename: Ana Flavia
authors.initials: AF
authors.lastname: Gomes Paiva
authors.affiliation: CIAMS, Univ. Paris-Sud, Université Paris-Saclay, 91405 Orsay Cedex France; APHP Rothschild Hospital and UPMC-Paris 6 University, 5 rue Santerre 75012 Paris, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Thoumie
authors.affiliation: CIAMS, Univ. Paris-Sud, Université Paris-Saclay, 91405 Orsay Cedex France; APHP Rothschild Hospital 5 rue Santerre 75012 Paris, France.
authors.forename: Besma
authors.initials: B
authors.lastname: Missaoui
mesh_terms: D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology*; D011187:Posture / Q000502:physiology; D011434:Proprioception / Q000502:physiology*; D014732:Vibration
keywords: Balance; Limits of equilibrium; Peripheral neuropathy; Proprioception; Strength