title: Synthesis of α-methylene-δ-oxo-γ-amino esters via Rh(ii)-catalyzed coupling of 1-sulfonyl-1,2,3-triazoles with Morita-Baylis-Hillman adducts.
abstract: A rhodium(ii)-catalyzed coupling of 1-sulfonyl-1,2,3-triazoles, prepared from 1-alkynes and sulfonyl azides, with Morita-Baylis-Hillman (MBH) adducts afforded highly functionalized α-methylene-δ-oxo-γ-amino esters in excellent yields with broad functional group tolerance. This transformation can also be successfully accomplished as a multicomponent all-in-one-pot reaction of 1-alkynes, sulfonyl azides and MBH adducts in the presence of Cu(i) and Rh(ii) catalysts.
authors.affiliation: Department of Chemistry and Nano Science (BK21 plus), Ewha Womans University, 03760 Seoul, Republic of Korea. Sanggi@ewha.ac.kr.
authors.forename: Hyun Ji
authors.initials: HJ
authors.lastname: Jeon
authors.affiliation: Department of Chemistry and Nano Science (BK21 plus), Ewha Womans University, 03760 Seoul, Republic of Korea. Sanggi@ewha.ac.kr.
authors.forename: Mi Soo
authors.initials: MS
authors.lastname: Kwak
authors.affiliation: Department of Chemistry and Nano Science (BK21 plus), Ewha Womans University, 03760 Seoul, Republic of Korea. Sanggi@ewha.ac.kr.
authors.forename: Da Jung
authors.initials: DJ
authors.lastname: Jung
authors.affiliation: Department of Chemistry and Nano Science (BK21 plus), Ewha Womans University, 03760 Seoul, Republic of Korea. Sanggi@ewha.ac.kr.
authors.forename: Jean
authors.initials: J
authors.lastname: Bouffard
authors.affiliation: Department of Chemistry and Nano Science (BK21 plus), Ewha Womans University, 03760 Seoul, Republic of Korea. Sanggi@ewha.ac.kr.
authors.forename: Sang-Gi
authors.initials: SG
authors.lastname: Lee