title: Comparison of the Effect of Lidocaine versus a Lidocaine-Bupivacaine Combination in a Periprostatic Nerve Block Undergoing Transrectal Ultrasound-Guided Prostate Biopsy: A Double-Blind Randomized Controlled Trial.
abstract: BACKGROUND
  To determine whether a combination of the long acting local anesthetic, bupivacaine, and lidocaine is better than lidocaine alone in the long-term pain control, which is a short-acting anesthetic.
  
  
  METHODS
  In group 1, periprostatic nerve block was applied to both neurovascular areas with 2% lidocaine (5 ml) in an isotonic solution (5 ml). In group 2, the combination of 2% lidocaine (5 ml) and 5mg/ml bupivacaine (5 ml) was used for the PPNB.
  
  
  RESULTS
  In the first 30 minutes the mean VAS scores of groups 1 and 2 were 2.1 ± 0.2 and 1.2 ± 0.1, respectively (p = 0.002). VAS scores of group II determined at 1, 2, 4, 6, and 8 hours after the biopsy were significantly lower since it was (p < 0.05).
  
  
  CONCLUSIONS
  While periprostatic nerve block for late phase pain control, applying a combination of a long-acting local anesthetic, such as bupivacaine, is effective in terms of pain control and patient comfort.
authors.affiliation: Department of Urology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Ali H
authors.initials: AH
authors.lastname: Yilmaz
authors.affiliation: Department of Anesthesiology and Reamination, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Elif
authors.initials: E
authors.lastname: Ziypak
authors.affiliation: Department of Urology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Tevfik
authors.initials: T
authors.lastname: Ziypak
authors.affiliation: Department of Anesthesiology and Reamination, Education and Research Hospital, Erzurum, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Aksoy
authors.affiliation: Department of Urology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Senol
authors.initials: S
authors.lastname: Adanur
authors.affiliation: Department of Urology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Kocakgol
authors.affiliation: Department of Urology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Saban O
authors.initials: SO
authors.lastname: Demirdogen
authors.affiliation: Department of Urology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Ozkan
authors.initials: O
authors.lastname: Polat
keywords: Biopsy; Bupivacaine; Periprostatic nevre block; TRUS-guided prostate biopsy