title: Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma.
abstract: OBJECTIVE
  To describe spongiform scleropathy in a patient with oculodermal melanosis and without evidence of uveal melanoma.
  
  
  METHODS
  Clinical-pathological correlation conducted in compliance with HIPPA (Health Insurance Privacy and Portability Act) regulations.
  
  
  RESULTS
  Melanoma-associated spongiform scleropathy was an incidental finding in an 87-year-old woman with oculodermal melanocytosis treated for primary orbital melanoma. All previously reported cases of this scleropathy have been associated with uveal melanoma.
  
  
  CONCLUSIONS
  The mechanism of scleral degeneration in melanoma-associated spongiform scleropathy is unknown, and its clinical and prognostic significance is speculative. This is the first case of a so-called melanoma-associated spongiform scleropathy reported in an eye without uveal melanoma.
authors.affiliation: Department of Ophthalmology, Morsani College of Medicine, University of South Florida, Tampa, Fla., USA.
authors.forename: Roshni U
authors.initials: RU
authors.lastname: Ranjit
authors.affiliation: Department of Ophthalmology, Morsani College of Medicine, University of South Florida, Tampa, Fla., USA.
authors.forename: Ilya M
authors.initials: IM
authors.lastname: Leyngold
authors.affiliation: Department of Ophthalmology, Morsani College of Medicine, University of South Florida, Tampa, Fla., USA; Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida, Tampa, Fla., USA.
authors.forename: Curtis E
authors.initials: CE
authors.lastname: Margo
keywords: Melanoma-associated spongiform scleropathy; Melanosis oculi; Nevus of Ota; Oculodermal melanosis; Scleral degeneration