title: A case report and short review on changing trends in the site of occurrence of adenomatoid odontogenic tumor: Unravelling the past 15 years.
abstract: Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion, with debatable histogenesis and variable histopathology. A systematic and diverse insight into the evolution, clinical presentation, histology, and immunohistochemical findings of this lesion is reviewed and presented. We reviewed the data published from 2000 to 2014 of approximately 255 cases that revealed a significant change in the incidence of predominant site involved, in contrast to the findings published by Reichart. We have also included the chronological order of events leading to the coining of the term AOT, which shows the curiosity that has been dedicated to understanding the lesion. Immunohistochemistry is considered to be a hallmark in pathology for learning the molecular pathogenesis and giving a correct final diagnosis. Several markers have been used to investigate and understand this lesion, and a compilation of the findings has been tabulated.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India.
authors.forename: Sneha
authors.initials: S
authors.lastname: Sethi
authors.affiliation: Department of Oral and Maxillofacial Pathology, Tatyasaheb Kore Dental College and Research Centre, Kohlapur, Maharashtra, India.
authors.forename: Manish
authors.initials: M
authors.lastname: Kumar
authors.affiliation: Department of Conservative Dentistry and Endodontics, DJ Dental College, Modinagar, Uttar Pradesh, India.
authors.forename: Pratul
authors.initials: P
authors.lastname: Aggarwal
authors.affiliation: Department of Prosthodontics, Tatyasaheb Kore Dental College and Research Centre, Kohlapur, Maharashtra, India.
authors.forename: H S
authors.initials: HS
authors.lastname: Indra Kumar
authors.affiliation: Department of Periodontics, Tatyasaheb Kore Dental College and Research Centre, Kohlapur, Maharashtra, India.
authors.forename: Chetan D
authors.initials: CD
authors.lastname: Sugandhi
authors.affiliation: Department of Oral Pathology, Tatyasaheb Kore Dental College and Research Centre, Kohlapur, Maharashtra, India.
authors.forename: Silvie
authors.initials: S
authors.lastname: Singh
keywords: Ameloblastoma; immunohistochemistry; incidence; odontogenesis