title: Schwartz-Jampel syndrome with gastroduodenal bleeding.
abstract: Schwartz-Jampel syndrome is a rare autosomal recessive disorder with joint contractures, generalized myotonia, skeletal anomalies, and facial dysmorphism. The patients with Schwartz-Jampel syndrome have muscle stiffness and electromyography reveals complex, repetitive discharges as myotonic discharges. It is unusual for a Schwartz-Jampel syndrome case to have recurrent gastrointestinal bleeding episodes. The stable endothelial barrier is provided by perlecan which is an important component of vascular structures. Thus, perlecan deficiency may cause recurrent gastroduodenal bleeding. Our report is unique with being the first reported Schwartz-Jampel syndrome case with gastrointestinal bleeding.
authors.affiliation: Department of Pediatrics, Division of Child Neurology, School of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: İpek
authors.initials: İ
authors.lastname: Polat
authors.affiliation: Department of Pediatrics, Division of Child Neurology, School of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Pakize
authors.initials: P
authors.lastname: Karaoğlu
authors.affiliation: Department of Pediatrics, Division of Child Neurology, School of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Uluç
authors.initials: U
authors.lastname: Yiş
authors.affiliation: Department of Pediatrics, Division of Child Neurology, School of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Semra Hız
authors.initials: SH
authors.lastname: Kurul
keywords: Electromyography; Schwartz–Jampel syndrome; muscle; myotonic discharges