title: Metabolic Bone Disease in Patients with Malabsorption.
abstract: Chronic inflammation and malabsorption in gastrointestinal disease can cause bone metabolism alterations and bone mineral loss in children and adults. Gastrointestinal disease is often forgotten as a cause of osteoporosis, osteopenia, or osteomalacia. The etiology of pathologic bone alterations in gastrointestinal disease is multifactorial. Bone alterations were thought to result simply from intestinal malabsorption, but a more complex interaction between cytokines and local/systemic factors influencing bone formation and resorption is envisaged. This review provides an updated discussion on bone alterations in patients with malabsorption due to celiac disease or inflammatory bowel disease.
authors.affiliation: Department of Radiology, Saint-Antoine Hospital, Paris, France.
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Phan
authors.affiliation: Department of Radiology, University of Foggia, Foggia, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Guglielmi
mesh_terms: D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000150:complications* / Q000000981:diagnostic imaging; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002446:Celiac Disease / Q000150:complications*; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications*