title: Two diseases one remedy? Systemic amyloidosis secondary to hidradenitis suppurativa: Treatment with infliximab.
abstract: Hidradenitis suppurativa, known as acne inversa, is a relapsing and chronic inflammatory skin disease affecting the skin folds. During the chronic course of the disease many local complications like fistulae to other tissues or systemic complications including anemia, secondary amyloidosis, lymphedema, nephrotic syndrome, artropathy may take place. Amyloid A amyloidosis is a rare complication of hidradenitis suppurativa, which has been described in a limited number of case reports. Herein, we present such a patient that had developed AA amyloidosis during the course of hidradenitis suppurativa. Both AA amyloidosis and hidradenitis suppurativa have responded to infliximab therapy which was shown by clinical recovery and by the improvement in renal functions.
authors.affiliation: Meram Faculty of Medicine, Department of Dermatology, Necmettin Erbakan University, Konya, Turkey.
authors.forename: İlkay
authors.initials: İ
authors.lastname: Özer
authors.affiliation: Department of Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey.
authors.forename: Cengiz
authors.initials: C
authors.lastname: Karaçin
authors.affiliation: Department of Dermatology, Gazi University Faculty of Medicine, Ankara, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Adışen
authors.affiliation: Department of Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey.
authors.forename: Galip
authors.initials: G
authors.lastname: Güz
authors.affiliation: Department of Dermatology, Gazi University Faculty of Medicine, Ankara, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ali Gürer
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D017497:Hidradenitis Suppurativa / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D000069285:Infliximab / Q000627:therapeutic use*; D008297:Male; D012074:Remission Induction; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D000069285:Infliximab
keywords: hidradenitis suppurativa; infliximab; systemic amyloidosis