title: Evaluation of artifact reduction in optical coherence tomography angiography with real-time tracking and motion correction technology.
abstract: Artifacts introduced by eye motion in optical coherence tomography angiography (OCTA) affect the interpretation of images and the quantification of parameters with clinical value. Eradication of such artifacts in OCTA remains a technical challenge. We developed an algorithm that recognizes five different types of motion artifacts and used it to evaluate the performance of three motion removal technologies. Onen facemaximum projection of flow images, the summed flow signal in each row and column and the correlation between neighboring rows and columns were calculated. Bright line artifacts were recognized by large summed flow signal. Drifts, distorted lines, and stretch artifacts exhibited abnormal correlation values. Residual lines were simultaneously a local maximum of summed flow and a local minimum of correlation. Tracking-assisted scanning integrated with motion correction technology (MCT) demonstrated higher performance than tracking or MCT alone in healthy and diabetic eyes.
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Acner
authors.initials: A
authors.lastname: Camino
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA; Optovue, Inc. 2800 Bayview Dr., Fremont, CA 94538, USA.
authors.forename: Miao
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Simon S
authors.initials: SS
authors.lastname: Gao
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Hwang
authors.affiliation: Optovue, Inc. 2800 Bayview Dr., Fremont, CA 94538, USA.
authors.forename: Utkarsh
authors.initials: U
authors.lastname: Sharma
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Wilson
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: David
authors.initials: D
authors.lastname: Huang
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Yali
authors.initials: Y
authors.lastname: Jia
keywords: (100.2980) Image enhancement; (170.4470) Ophthalmology; (170.4500) Optical coherence tomography; (330.4150) Motion detection