title: Accuracy of ultrasound in prediction of rectosigmoid infiltration in epithelial ovarian cancer.
abstract: OBJECTIVE
  To examine prospectively the accuracy of ultrasound in predicting rectosigmoid tumor infiltration in patients with epithelial ovarian cancer.
  
  
  METHODS
  Patients referred for a suspicious pelvic mass between 2012 and 2014 were examined by ultrasound following the standard protocol for assessment of tumor infiltration. Of the 245 patients examined, 191 had proven ovarian cancer and underwent primary surgery and were included in the analysis. Patients with apparently benign or inoperable disease were excluded. Rectosigmoid infiltration was evaluated by histopathology or according to perioperative findings. Clinical, pathological and laboratory parameters were analyzed as factors potentially affecting the sensitivity and specificity of sonography.
  
  
  RESULTS
  The sensitivity of ultrasound in detecting rectosigmoid infiltration in patients with ovarian cancer was 86.3%, with specificity of 95.8%, positive predictive value of 92.6%, negative predictive value of 91.9% and overall accuracy of 92.1%.
  
  
  CONCLUSIONS
  Ultrasound is a highly accurate method for detecting rectosigmoid tumor infiltration in ovarian cancer patients, and thus, can be used for planning adequate management, including patient consultation, surgical team planning, suitable operating time and postoperative care. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.
authors.affiliation: Gynecologic Oncology Center, Department of Gynecology and Obstetrics, Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: M
authors.initials: M
authors.lastname: Zikan
authors.affiliation: Gynecologic Oncology Center, Department of Gynecology and Obstetrics, Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: D
authors.initials: D
authors.lastname: Fischerova
authors.affiliation: Gynecologic Oncology Center, Department of Gynecology and Obstetrics, Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: I
authors.initials: I
authors.lastname: Semeradova
authors.affiliation: Gynecologic Oncology Center, Department of Gynecology and Obstetrics, Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Slama
authors.affiliation: Department of Pathology, Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: P
authors.initials: P
authors.lastname: Dundr
authors.affiliation: Department of Gynecology and Obstetrics, Masaryk University, Faculty of Medicine, Brno, Czech Republic.
authors.forename: V
authors.initials: V
authors.lastname: Weinberger
authors.affiliation: Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic.
authors.forename: L
authors.initials: L
authors.lastname: Dusek
authors.affiliation: Gynecologic Oncology Center, Department of Gynecology and Obstetrics, Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic.
authors.forename: D
authors.initials: D
authors.lastname: Cibula
mesh_terms: D000328:Adult; D000368:Aged; D000077216:Carcinoma, Ovarian Epithelial; D012809:Colon, Sigmoid / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000000981:diagnostic imaging* / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D012007:Rectum / Q000000981:diagnostic imaging / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012811:Sigmoid Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D014463:Ultrasonography
keywords: debulking surgery; ovarian cancer; rectosigmoid tumor infiltration; staging; surgery planning