title: Cirrhotic Cardiomyopathy: Another Case of a Successful Approach to Treatment of Hepatorenal Syndrome.
abstract: Hepatorenal syndrome (HRS) is defined as a failure of renal function, potentially reversible, in patients with liver cirrhosis and ascites. Recently, a component of cardiomyopathy associated with HRS was described, but the use of positive inotropic medicine as part of the treatment of the acute phase has not been extensively evaluated. We report a second case in our hospital of a patient with HRS type I without previous heart disease, with secondary hemodynamic decompensation due to liver disease, in which the abnormalities in systolic function by speckle-tracking echocardiography were observed and could be reversed by the use of inotropes. After partial response to current therapies, the patient presented a clinical and laboratorial response with improvement of renal function after infusion of dobutamine. Clinical studies are needed for the therapy approach to HRS taking into account myocardial dysfunction as a major contributing factor for renal dysfunction.
authors.affiliation: Department of Internal Medicine, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Brazil.
authors.forename: Luis Otávio
authors.initials: LO
authors.lastname: Mocarzel
authors.affiliation: Department of Internal Medicine, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Brazil.
authors.forename: Jessica
authors.initials: J
authors.lastname: Bicca
authors.affiliation: Department of Internal Medicine, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Brazil.
authors.forename: Luiza
authors.initials: L
authors.lastname: Jarske
authors.affiliation: Department of Internal Medicine, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Brazil.
authors.forename: Thamires
authors.initials: T
authors.lastname: Oliveira
authors.affiliation: Department of Internal Medicine, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Brazil.
authors.forename: Pedro
authors.initials: P
authors.lastname: Lanzieri
authors.affiliation: Department of Internal Medicine, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Brazil.
authors.forename: Ronaldo
authors.initials: R
authors.lastname: Gismondi
authors.affiliation: Department of Cardiology, Hospital Universitário Antônio Pedro (HUAP), Niterói, Brazil.
authors.forename: Mario Luiz
authors.initials: ML
authors.lastname: Ribeiro
keywords: Cirrhosis; Cirrhotic cardiomyopathy; Heart failure; Hepatic insufficiency; Hepatorenal syndrome; Left ventricular diastolic dysfunction