title: Magnetic resonance neurographic confirmation of extensive Plexiform neurofibroma in neurofibromatosis-1 presenting as ambiguous genitalia.
abstract: Genitourinary involvement of neurofibromatosis is uncommon and genital neurofibromatosis is even rarer. Involvement of clitoris by neurofibroma can lead to clitoromegaly masquerading as a male penis. We report such a case of ambiguous genitalia in a 7-year-old female child presenting with clitoromegaly since birth, in which magnetic resonance imaging (MRI) revealed the presence of extensive neurofibromatosis in the clitoris and lumbosacral regions. We emphasize the central role of MRI in evaluation of hormonal and non-hormonal causes of ambiguous genitalia. We further discuss the merits of including MR neurography in the imaging protocol for comprehensive delineation of neurofibromatosis.
authors.affiliation: Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Ishan
authors.initials: I
authors.lastname: Kumar
authors.affiliation: Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Verma
authors.affiliation: Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Ritu
authors.initials: R
authors.lastname: Ojha
authors.affiliation: Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Priyanka
authors.initials: P
authors.lastname: Aggarwal
authors.affiliation: Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Ram C
authors.initials: RC
authors.lastname: Shukla
authors.affiliation: Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Arvind
authors.initials: A
authors.lastname: Srivastava
keywords: Clitoromegaly; MR neurography; genital neurofibromatosis