title: From bosentan to macitentan for pulmonary arterial hypertension and adult congenital heart disease: Further improvement?
authors.affiliation: Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands; NLHI - Netherlands Heart Institute, Utrecht, The Netherlands.
authors.forename: Ilja M
authors.initials: IM
authors.lastname: Blok
authors.affiliation: Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands; NLHI - Netherlands Heart Institute, Utrecht, The Netherlands.
authors.forename: Annelieke C M J
authors.initials: ACMJ
authors.lastname: van Riel
authors.affiliation: Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Arie P J
authors.initials: APJ
authors.lastname: van Dijk
authors.affiliation: Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands; NLHI - Netherlands Heart Institute, Utrecht, The Netherlands.
authors.forename: Barbara J M
authors.initials: BJM
authors.lastname: Mulder
authors.affiliation: Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: b.j.bouma@amc.nl.
authors.forename: Berto J
authors.initials: BJ
authors.lastname: Bouma
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D000077300:Bosentan; D015331:Cohort Studies; D057915:Drug Substitution / Q000639:trends*; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011743:Pyrimidines / Q000627:therapeutic use*; D013449:Sulfonamides / Q000627:therapeutic use*
chemical_list: D000959:Antihypertensive Agents; D011743:Pyrimidines; D013449:Sulfonamides; D000077300:Bosentan; C533860:macitentan
keywords: Bosentan; Congenital heart disease; Macitentan; Pulmonary arterial hypertension