title: A new challenge for the world: the eradication of polio.
abstract: Poliovirus infects 100% of susceptible individuals and causes acute flaccid paralysis in one out of200 infections. Type 1 causes epidemic poliomyelitis; type 2 has been eradicated worldwide; and type 3 is close to being eradicated. In this region, the last case of wild poliovirus occurred in Peru in 1991. There are still two endemic countries: Afghanistan and Pakistan, but countries where there is no circulation of the wild poliovirus have also reported imported cases of polio. In May 2012, the World Health Assembly declared the polio eradication a programmatic emergency for global public health and, as a result, developed the Polio Eradication and Endgame Strategic Plan 2013-2018. The Plan has four objectives: 1) Detect and interrupt all poliovirus transmission and maintain surveillance of acute flaccid paralysis in children < 15 years. 2) Strengthen immunization systems and withdraw oral polio vaccine by the first trimester of 2016. Replace the trivalent oral polio vaccine with the bivalent oral vaccine, containing serotypes 1 and 3, and introduce the inactivated polio vaccine in all immunization schedules to maintain immunity against poliovirus type 2. 3) Contain poliovirus and certify interruption of transmission. 4) Plan the exploitation of the fight against polio and its impact on public health. The plan is expected to reach its goals by 2018; all use of the oral polio vaccine will be interrupted thereafter. Change in immunization schedules will require pediatricians to provide advice and guidance to families depending on the varied situations of everyday practice.
authors.affiliation: Epidemiología, Hospital de Niños R. Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina. angelagentile21@gmail.com.|Comité Regional para la Erradicación de la Poliomielitis, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Ángela
authors.initials: Á
authors.lastname: Gentile
authors.affiliation: Comité Nacional de Infectología, SAP, Argentina.
authors.forename: Héctor
authors.initials: H
authors.lastname: Abate
mesh_terms: D000293:Adolescent; D002648:Child; D060740:Disease Eradication; D014943:Global Health; D006801:Humans; D007115:Immunization Schedule; D011051:Poliomyelitis / Q000517:prevention & control*; D011055:Poliovirus Vaccine, Oral; D023321:Poliovirus Vaccines / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D011055:Poliovirus Vaccine, Oral; D023321:Poliovirus Vaccines
keywords: Eradication; Immunization; Poliomyelitis