title: Direct sample introduction-gas chromatography-mass spectrometry for the determination of haloanisole compounds in cork stoppers.
abstract: A solventless analytical method is proposed for analyzing the compounds responsible for cork taint in cork stoppers. Direct sample introduction (DSI) is evaluated as a sample introduction system for the gas chromatography-mass spectrometry (GC-MS) determination of four haloanisoles (HAs) in cork samples. Several parameters affecting the DSI step, including desorption temperature and time, gas flow rate and other focusing parameters, were optimized using univariate and multivariate approaches. The proposed method shows high sensitivity and minimises sample handling, with detection limits of 1.6-2.6ngg-1, depending on the compound. The suitability of the optimized procedure as a screening method was evaluated by obtaining decision limits (CCα) and detection capabilities (CCβ) for each analyte, which were found to be in 6.9-11.8 and 8.7-14.8ngg-1, respectively, depending on the compound. Twenty-four cork samples were analysed, and 2,4,6-trichloroanisole was found in four of them at levels between 12.6 and 53ngg-1.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100 Murcia, Spain.
authors.forename: J I
authors.initials: JI
authors.lastname: Cacho
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100 Murcia, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Nicolás
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100 Murcia, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Viñas
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100 Murcia, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Campillo
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100 Murcia, Spain. Electronic address: hcordoba@um.es.
authors.forename: M
authors.initials: M
authors.lastname: Hernández-Córdoba
mesh_terms: D000840:Anisoles / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D014920:Wine
chemical_list: D000840:Anisoles; C110228:2,4,6-trichloroanisole
keywords: Cork stoppers; Cork taint; Direct sample introduction; Gas chromatography-mass spectrometry; Haloanisoles