title: [CCAFU french national guidelines 2016-2018 on upper tract tumors].
abstract: BACKGROUND
  The purpose was to propose an update of the french guidelines from the national committee CCAFU on upper tract urothelial carcinomas (UTUC).
  
  
  METHODS
  A systematic Medline search was performed between 2013 and 2016, as regards diagnosis, options of treatment and follow-up of UTUC, to evaluate different references with levels of evidence.
  
  
  RESULTS
  The diagnosis of this rare pathology is based on CT-scan acquisition during excretion and ureteroscopy with histological biopsies. Radical nephroureterectomy (RNU) remains the gold standard for surgical treatment, nevertheless a conservative endoscopic approach can be proposed for low risk lesion: unifocal tumour, possible complete resection and low grade and absence of invasion on CT-scan. Close monitoring with endoscopic follow-up (flexible ureteroscope) in compliant patients is therefore necessary. After RNU, bladder instillation of chemotherapy is recommended to reduced risk of baldder recurrence. The place of systemic therapy (adjuvant and neoadjuvant chemotherapy) remains to define.
  
  
  CONCLUSIONS
  These updated guidelines will contribute to increase the level of urological care for diagnosis and treatment for UTUC. © 2016 Elsevier Masson SAS. All rights reserved.
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France. Electronic address: morgan.roupret@aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Rouprêt
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Colin
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Xylinas
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Compérat
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Dubosq
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Houédé
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Larré
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Masson-Lecomte
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Neuzillet
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: G
authors.initials: G
authors.lastname: Pignot
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Puech
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Roumiguié
authors.affiliation: Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Méjean
mesh_terms: D000465:Algorithms; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D014516:Ureteral Neoplasms / Q000175:diagnosis* / Q000628:therapy*
keywords: Bassinet; Cancer; Carcinome urothélial; Cytologie urinaire; Kidney; Rein; Renal pelvis; Survie; Survival; Ureter; Ureteroscopy; Uretère; Urinary cytology; Urothelial; Urétéroscopie; carcinoma