title: New Developments in Interventional Oncology: Liver Metastases From Colorectal Cancer.
abstract: Colorectal cancer is the third leading cause of cancer death in the United States. Although hepatic excision is the first-line treatment for colorectal liver metastasis (CRLM), few patients are candidates. Locoregional therapy (LRT) encompasses minimally invasive techniques practiced by interventional radiology. These include ablative treatments (radiofrequency ablation, microwave ablation, and cryosurgical ablation) and transcatheter intra-arterial therapy (hepatic arterial infusion chemotherapy, transarterial "bland" embolization, transarterial chemoembolization, and radioembolization with yttrium 90). The National Comprehensive Cancer Network recommends LRT for unresectable CRLM refractory to chemotherapy. The following is a review of LRT in CRLM, including salient features, advantages, limitations, current roles, and future considerations.
authors.affiliation: From the *Department of Radiology, Section of Interventional Radiology, Northwestern Memorial Hospital, Robert H. Lurie Comprehensive Cancer Center; †Department of Surgery, Division of Transplantation, Comprehensive Transplant Center; and ‡Department of Medicine, Division of Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL.
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Kallini
authors.forename: Ahmed
authors.initials: A
authors.lastname: Gabr
authors.forename: Nadine
authors.initials: N
authors.lastname: Abouchaleh
authors.forename: Rehan
authors.initials: R
authors.lastname: Ali
authors.forename: Ahsun
authors.initials: A
authors.lastname: Riaz
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Lewandowski
authors.forename: Riad
authors.initials: R
authors.lastname: Salem
mesh_terms: D001918:Brachytherapy; D017115:Catheter Ablation; D015179:Colorectal Neoplasms / Q000473:pathology / Q000628:therapy*; D004621:Embolization, Therapeutic; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy*