title: Determination of ceruloplasmin, some other acute phase proteins, and biochemical parameters in cows with endometritis.
abstract: OBJECTIVE
  The aim of this study is to determine serum ceruloplasmin levels in cows with endometritis of varying degrees of severity and to establish whether or not there is a correlation between acute phase protein (APP) levels and biochemical parameters.
  
  
  METHODS
  The study was conducted with 100 Brown Swiss cows (3-8 years of age) on days 28-32 postpartum. Cows were divided into endometritis (mild, moderate, and severe endometriosis) and healthy groups based on ultrasonography, vaginoscopy, and cytological examination. Blood samples were collected from all cows. Levels of haptoglobin (Hp), serum amyloid A (SAA), ceruloplasmin, albumin, and some biochemical parameters were analyzed.
  
  
  RESULTS
  Hp, SAA, and ceruloplasmin levels were higher in cows with endometritis than in healthy cows (p=0.001), and the levels of these APPs increased as endometritis became more severe (p=0.001). Some significant correlations were found between APPs and the biochemical parameters that were analyzed. In conclusion, it was determined that ceruloplasmin levels increase significantly in the presence of endometritis and proportionate to the severity of endometritis. A significant correlation was found between ceruloplasmin levels and Hp and SAA levels.
  
  
  CONCLUSIONS
  It was concluded that ceruloplasmin levels can be used in the diagnosis of endometritis as an alternative to Hp and SAA levels.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, University of Kafkas, Kars, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Kaya
authors.affiliation: Department of Biochemistry, Faculty of Veterinary Medicine, University of Kafkas, Kars, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Merhan
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, University of Kafkas, Kars, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Kacar
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, University of Ataturk, Erzurum, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Colak
authors.affiliation: Department of Veterinary Health, Kars School of Higher Vocational Education, University of Kafkas, Kars, Turkey.
authors.forename: K
authors.initials: K
authors.lastname: Bozukluhan
keywords: albumin; ceruloplasmin; cow; endometritis; haptoglobin; serum amyloid A