title: Erythema multiforme-like cutaneous lesions in monomorphic epitheliotropic intestinal T-cell lymphoma: a rare case report.
abstract: Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), also known as Type II enteropathy-associated T-cell lymphoma (EATL), is an aggressive peripheral T-cell lymphoma. EATL generally presents in adults with gastrointestinal symptoms. Skin involvement is very rare, found only in approximately five percent of patients. The authors report a 67-year-old Asian male who presented with chronic diarrhea and developed erythema multiforme-like cutaneous lesions. A skin biopsy revealed extensive pagetoid spread of atypical lymphocytes in the epidermis. The results of an immunohistochemistry test led to a diagnosis of MEITL. This report points to the need for dermatologists and dermatopathologists to consider a possible diagnosis of MEITL when encountering similar cases.
authors.affiliation: Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
authors.forename: Kumpol
authors.identifier: http://orcid.org/0000-0001-5256-827X
authors.initials: K
authors.lastname: Aiempanakit
authors.affiliation: Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
authors.forename: Chitiarpa
authors.initials: C
authors.lastname: Amatawet
authors.affiliation: Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
authors.forename: Kanokphorn
authors.initials: K
authors.lastname: Chiratikarnwong
authors.affiliation: Department of Pathology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
authors.forename: Sauvarat
authors.initials: S
authors.lastname: Auepemkiate
authors.affiliation: Department of Pathology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
authors.forename: Kanita
authors.initials: K
authors.lastname: Kayasut
authors.affiliation: Department of Pathology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
authors.forename: Supaporn
authors.initials: S
authors.lastname: Suwiwat
authors.affiliation: Hematology Unit, Bangkok-Hatyai Hospital, Songkhla, Thailand.
authors.forename: Benjawan
authors.initials: B
authors.lastname: Apinantriyo
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D058527:Enteropathy-Associated T-Cell Lymphoma / Q000150:complications / Q000473:pathology*; D004892:Erythema Multiforme / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: enteropathy-associated T-cell lymphoma; erythema multiforme-like; monomorphic epitheliotropic intestinal T-cell lymphoma; pagetoid