title: Bottom-Up Structuring and Site-Selective Modification of Hydrogels Using a Two-Photon [2+2] Cycloaddition of Maleimide.
abstract: Creating hydrogel systems to mimic the extracellular matrix is often limited by their static nature. The use of a two-photon [2+2] cycloaddition of maleimide groups to structure surfaces, to create hydrogels, and add 3D modifications with sub-micrometer precision is reported. The absence of photoinitiators and usage of near-infrared light is promising for future in vivo studies.
authors.affiliation: B CUBE - Center for Molecular Bioengineering, Technische Universität Dresden, Arnoldstraße 18, 01307, Dresden, Germany.|Leibniz-Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC), Hohe Straße 6, 01069, Dresden, Germany.
authors.forename: Christiane
authors.initials: C
authors.lastname: Jungnickel
authors.affiliation: Leibniz-Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC), Hohe Straße 6, 01069, Dresden, Germany.
authors.forename: Mikhail V
authors.initials: MV
authors.lastname: Tsurkan
authors.affiliation: B CUBE - Center for Molecular Bioengineering, Technische Universität Dresden, Arnoldstraße 18, 01307, Dresden, Germany.
authors.forename: Kristin
authors.initials: K
authors.lastname: Wogan
authors.affiliation: Leibniz-Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC), Hohe Straße 6, 01069, Dresden, Germany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Werner
authors.affiliation: B CUBE - Center for Molecular Bioengineering, Technische Universität Dresden, Arnoldstraße 18, 01307, Dresden, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Schlierf
keywords: [2+2] cycloaddition; hydrogels; maleimide; micrometer precision postmodification; two-photon chemistry