title: Renal tuberculosis presenting as acute pyelonephritis - A rarity.
abstract: One of the major health problems faced particularly by the developing world since ages is that of tuberculosis (TB). Genito-urinary tuberculosis (GUTB) is the second most common extrapulmonary TB, with kidney being the most frequent site of infection. Due to the diverse and atypical clinical manifestations of urinary TB, the disease is easy to misdiagnose. The diagnosis of renal TB should be suspected in a nonspecific bacterial cystitis associated with a therapeutic failure or a sterile pyuria and a past history of pulmonary TB with important radiologic findings, particularly with the help of CT scan. Here, we describe a case of renal TB where no clinical or radiological features suggestive of renal TB were present. The diagnosis was only evident after the histopathological examination of the excised kidney. This case highlights the importance of suspecting renal TB as an important cause of kidney disease, which can lead to irreversible renal function loss particularly in an endemic area, and also the diversity that this disease may acquire in its presentation leading to misdiagnosis. In such a case, particularly in a high endemic area for TB, therapeutic trial of ATT may also be considered to avoid unnecessary surgical intervention and end-stage renal disease.
authors.affiliation: Department of Pulmonary Medicine, King George Medical University, Lucknow, India.
authors.forename: Ajay Kumar
authors.initials: AK
authors.lastname: Verma
authors.affiliation: Department of Pulmonary Medicine, King George Medical University, Lucknow, India.
authors.forename: Ashwini Kumar
authors.initials: AK
authors.lastname: Mishra
authors.affiliation: Department of Urology, King George Medical University, Lucknow, India.
authors.forename: Manoj
authors.initials: M
authors.lastname: Kumar
authors.affiliation: Department of Pulmonary Medicine, King George Medical University, Lucknow, India. Electronic address: skantpulmed@gmail.com.
authors.forename: Surya
authors.initials: S
authors.lastname: Kant
authors.affiliation: Department of Pulmonary Medicine, King George Medical University, Lucknow, India.
authors.forename: Anubhuti
authors.initials: A
authors.lastname: Singh
authors.affiliation: Department of Pathology, King George Medical University, Lucknow, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Singh
mesh_terms: D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D011704:Pyelonephritis / Q000175:diagnosis*; D014398:Tuberculosis, Renal / Q000175:diagnosis*; D055815:Young Adult
keywords: Acute pyelonephritis; Kidney; Tuberculosis