title: Anterior Chamber Non-Hodgkin Lymphoma of the Iris Masquerading as Uveitis-Glaucoma-Hyphema Syndrome.
abstract: OBJECTIVE
  To report a case of iris non-Hodgkin lymphoma initially thought to be uveitis-glaucoma-hyphema (UGH) syndrome.
  
  
  METHODS
  We reviewed the clinical, radiographic, and histopathologic findings in a patient with recurrent hyphemas and increased ocular pressure who eventually was found to have a rapidly growing iris mass.
  
  
  RESULTS
  An 89-year-old man with a history of cataract extraction and mantle cell lymphoma developed recurrent hyphema, which was subsequently revealed to be due to an iris mass. A biopsy revealed non-Hodgkin lymphoma that could not be formally subclassified but was suspicious for mantle cell lymphoma. The tumor showed a partial response to ibrutinib.
  
  
  CONCLUSIONS
  Iris lymphoma can masquerade as a cause of recurrent hyphema after cataract extraction. Ophthalmologists should be aware of this presentation, especially in patients with a history of lymphoma.
authors.affiliation: Department of Ophthalmology and Visual Science, New Haven, Conn., USA.
authors.forename: Angela C
authors.initials: AC
authors.lastname: Gauthier
authors.affiliation: Department of Ophthalmology and Visual Science, New Haven, Conn., USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Nguyen
authors.affiliation: Department of Pathology, Yale School of Medicine, New Haven, Conn., USA.
authors.forename: William R
authors.initials: WR
authors.lastname: Munday
authors.affiliation: Department of Pathology, Yale School of Medicine, New Haven, Conn., USA.
authors.forename: Mina L
authors.initials: ML
authors.lastname: Xu
authors.affiliation: Department of Ophthalmology and Visual Science, New Haven, Conn., USA; Department of Ophthalmic Oncology, Smilow Cancer Hospital, New Haven, Conn., USA.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Materin
keywords: Hyphema; Iris; Mantle cell lymphoma; Non-Hodgkin lymphoma; Uveitis