title: Gastroduodenal Ulceration in Small Animals: Part 2. Proton Pump Inhibitors and Histamine-2 Receptor Antagonists.
abstract: In the first part of this review, we discussed the pathophysiology and epidemiology of gastric acid secretion and the epidemiology of gastroduodenal ulceration in dogs and cats. In this section, we discuss the pharmacology and evidence-based clinical use of histamine-2 receptor antagonists and proton pump inhibitors.
authors.affiliation: From the Centre Vétérinaire Daubigny, Quebec, Canada (E.D.); and the Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts (L.R., C.R.L.W.).
authors.forename: Evence
authors.initials: E
authors.lastname: Daure
authors.affiliation: From the Centre Vétérinaire Daubigny, Quebec, Canada (E.D.); and the Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts (L.R., C.R.L.W.).
authors.forename: Linda
authors.initials: L
authors.lastname: Ross
authors.affiliation: From the Centre Vétérinaire Daubigny, Quebec, Canada (E.D.); and the Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts (L.R., C.R.L.W.).
authors.forename: Cynthia R L
authors.initials: CR
authors.lastname: Webster
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D002415:Cats; D004285:Dogs; D006632:Histamine; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D010437:Peptic Ulcer / Q000188:drug therapy / Q000662:veterinary*; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*
chemical_list: D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists; D054328:Proton Pump Inhibitors; D006632:Histamine