title: [Obscure gastrointestinal bleeding due to gastrointestinal stromal tumors].
abstract: BACKGROUND
  The gastrointestinal stromal tumours (GIST) are the most common soft tissue sarcomas of the digestive tract. They are usually found in the stomach (60-70%) and small intestine (25-30%) and, less commonly, in the oesophagus, mesentery, colon, or rectum. The symptoms present at diagnosis are, gastrointestinal bleeding, abdominal pain, abdominal mass, or intestinal obstruction. The type of symptomatology will depend on the location and size of the tumour. The definitive diagnosis is histopathological, with 95% of the tumours being positive for CD117.
  
  
  METHODS
  This is an observational and descriptive study of 5cases of small intestinal GIST that presented with gastrointestinal bleeding as the main symptom. The period from the initial symptom to the diagnosis varied from 1 to 84 months. The endoscopy was inconclusive in all of the patients, and the diagnosis was made using computed tomography and angiography. Treatment included resection in all patients. The histopathological results are also described.
  
  
  CONCLUSIONS
  GIST can have multiple clinical pictures and unusual symptoms, such as obscure gastrointestinal bleeding. The use of computed tomography and angiography has shown to be an important tool in the diagnosis with patients with small intestine GISTs.
authors.affiliation: Servicio de Gastrocirugía, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors.forename: Larry
authors.initials: L
authors.lastname: Romero-Espinosa
authors.affiliation: Servicio de Gastrocirugía, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México. Electronic address: lsouza269@gmail.com.
authors.forename: Luis Manuel
authors.initials: LM
authors.lastname: Souza-Gallardo
authors.affiliation: Servicio de Gastrocirugía, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Martínez-Ordaz
authors.affiliation: Servicio de Gastrocirugía, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors.forename: Teodoro
authors.initials: T
authors.lastname: Romero-Hernández
authors.affiliation: Servicio de Gastrocirugía, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors.forename: Mauricio
authors.initials: M
authors.lastname: de la Fuente-Lira
authors.affiliation: Servicio de Gastrocirugía, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.
authors.forename: Jorge
authors.initials: J
authors.lastname: Arellano-Sotelo
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D000072226:Computed Tomography Angiography; D004621:Embolization, Therapeutic; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000628:therapy; D046152:Gastrointestinal Stromal Tumors / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D007081:Ileostomy; D007580:Jejunal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D008297:Male; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents
keywords: Gastrointestinal stromal tumor; Intestino delgado; Jejunum; Obscure gastrointestinal bleeding; Sangrado de tubo digestivo de origen oscuro; Small intestine; Tumor de estroma gastrointestinal; Yeyuno