title: Depressive symptoms and prevalence of erectile dysfunction in Japanese patients with type 2 diabetes mellitus: the Dogo Study.
abstract: In several studies of patients with type 2 diabetes mellitus, a positive association between depressive symptoms and erectile dysfunction (ED) has been reported. No evidence exists, however, regarding the association between depressive symptoms and ED among Japanese patients with type 2 diabetes mellitus. Thus, we examined this issue among Japanese patients with type 2 diabetes mellitus. Study subjects were 469 male Japanese patients with type 2 diabetes mellitus, aged 19 years or over. ED, moderate to severe ED and severe ED were defined as present when a subject had a Sexual Health Inventory for Men score <22, <12 and <8, respectively. Depressive symptoms were defined as present when a subject had a Self-Rating Depression Scale (SDS) score >49. Adjustment was made for age, body mass index, waist, duration of type 2 diabetes, current smoking, current drinking, hypertension, dyslipidemia, coronary artery disease, stroke, glycated hemoglobin and diabetic neuropathy. The prevalence values of depressive symptoms, moderate to severe ED and severe ED were 15.1%, 64.2% and 51.0%, respectively. Depressive symptoms were independently positively associated with moderate to severe ED and severe ED (adjusted odds ratios were 2.23 (95% confidence interval (CI): 1.17-4.43) and 1.86 (95% CI: 1.04-3.41), respectively). In Japanese patients with type 2 diabetes mellitus, depressive symptoms may be associated with ED.
authors.affiliation: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan.|Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Toon, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Furukawa
authors.affiliation: Department of Internal Medicine, Yawatahama General City Hospital, Yawatahama, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sakai
authors.affiliation: Department of Internal Medicine, Matsuyama Shimin Hospital, Matsuyama, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Niiya
authors.affiliation: Department of Internal Medicine, Saiseikai Matsuyama Hospital, Matsuyama, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Miyaoka
authors.affiliation: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyake
authors.affiliation: Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.affiliation: Department of Public Health, Juntendo University School of Medicine, Bunkyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Maruyama
authors.affiliation: Department of Internal Medicine, Ehime Prefectural Central Hospital, Matuayama, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ueda
authors.affiliation: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan.|Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Senba
authors.affiliation: Department of Internal Medicine, Saiseikai Saijo Hospital, Saijo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Torisu
authors.affiliation: Department of Internal Medicine, Ehime Niihama Hospital, Niihama, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Minami
authors.affiliation: Department of Internal Medicine, Saiseikai Imabari Hospital, Imabari, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Onji
authors.affiliation: Department of Public Health, Juntendo University School of Medicine, Bunkyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tanigawa
authors.affiliation: Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: B
authors.initials: B
authors.lastname: Matsuura
authors.affiliation: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hiasa
authors.affiliation: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan.|Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Toon, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000368:Aged; D003863:Depression / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D007172:Erectile Dysfunction / Q000453:epidemiology* / Q000523:psychology*; D006801:Humans; D007564:Japan; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires