title: Vitamin D status and body mass index in children with atopic dermatitis: A pilot study in Italian children.
abstract: Vitamin D (vitD) is involved in important regulatory functions of the innate and adaptive immune system. So, it has been hypothesized that vitD might influence the course of atopic dermatitis (AD). Also obesity may have impact on immune system. The aim of our study was to investigate vitamin D status and body mass index (BMI) in urban children with AD.
  
  
  
  52 children with AD and 43 healthy children were enrolled. SCORAD, BMI and serum vitD levels were evaluated.
  
  
  
  There was an association between vitamin D and the AD occurrence but neither between vitamin D and the AD severity, nor between vitamin D and BMI. A positive correlation was observed between BMI and the AD severity in males.
  
  
  
  This study highlights the complex inter-relationships among atopic dermatitis severity, vitamin D and body mass index and suggests the need to investigate the role of genetic factors and/or gender-related differences to possibly identify new prevention strategies.
authors.affiliation: Department of Pediatrics, San Paolo Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
authors.forename: Enza
authors.initials: E
authors.lastname: D'Auria
authors.affiliation: Department of Pediatrics, Fatebenefratelli Hospital, University of Milan, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Barberi
authors.affiliation: Pediatric Dermatology - Dermatologic Clinic, San Paolo Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
authors.forename: Amilcare
authors.initials: A
authors.lastname: Cerri
authors.affiliation: Pediatric Dermatology - Dermatologic Clinic, San Paolo Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Boccardi
authors.affiliation: Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Turati
authors.affiliation: Department of Pediatrics, San Paolo Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Sortino
authors.affiliation: Department of Pediatrics, San Paolo Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Banderali
authors.affiliation: Department of Medicine, IRCCS - Azienda Ospedaliera Universitaria San Martino-IST, Largo R. Benzi 10, 16132, Genoa, Italy. Electronic address: gio.cip@libero.it.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Ciprandi
mesh_terms: D015992:Body Mass Index; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003876:Dermatitis, Atopic / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D006801:Humans; D056747:Immunomodulation; D007558:Italy / Q000453:epidemiology; D008297:Male; D010865:Pilot Projects; D012720:Severity of Illness Index; D014807:Vitamin D / Q000097:blood*
chemical_list: D014807:Vitamin D
keywords: Atopic dermatitis; Body mass index; Children; Vitamin D