title: Use of a 350-mm2Baerveldt glaucoma drainage device to maintain vision and control intraocular pressure in dogs with glaucoma: a retrospective study (2013-2016).
abstract: OBJECTIVE
  To evaluate the 350-mm2Baerveldt glaucoma drainage device (GDD) in dogs with refractory glaucoma when modifications to address postoperative hypotony (extraluminal ligature; intraluminal stent) and the fibroproliferative response (intraoperative Mitomycin-C; postoperative oral colchicine and prednisolone) are implemented as reported in human ophthalmology.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Twenty-eight client-owned dogs (32 eyes) including seven dogs (nine eyes) with primary glaucoma and 21 dogs (23 eyes) with secondary glaucoma.
  
  
  METHODS
  The medical records of all dogs undergoing placement of a 350-mm2Baerveldt GDD at a veterinary ophthalmology referral service between 2013 and 2016 were reviewed. Signalment, diagnosis, duration and previous treatment of glaucoma, previous intraocular surgery, IOP, visual, and surgical outcomes were recorded.
  
  
  RESULTS
  IOP was maintained <20mmHg in 24 of 32 (75.0%) eyes. Fourteen eyes (43.8%) required no adjunctive treatments to maintain this IOP control. Fewer doses of glaucoma medication were required following surgery. Vision was retained in 18 of 27 (66.7%) eyes with vision at the time of surgery. No eyes that were blind at the time of surgery (n = 5) had restoration of functional vision. Complications following surgery included hypotony (26/32; 81.3%), intraocular hypertension (24/32; 75.0%), and fibrin formation within the anterior chamber (20/32; 62.5%). The average follow-up after placement of the GDD was 361.1 days (median 395.6 days).
  
  
  CONCLUSIONS
  Efforts to minimize postoperative hypotony and address the fibroproliferative response following placement of a 350-mm2Baerveldt GDD showed an increased success rate to other reports of this device in dogs and offers an alternative surgical treatment for controlling intraocular pressure in dogs with glaucoma.
authors.affiliation: Department of Ophthalmology and Eye Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
authors.forename: Kathleen L
authors.identifier: http://orcid.org/0000-0003-2548-2969
authors.initials: KL
authors.lastname: Graham
authors.affiliation: Ophthalmology Department, Dick White Referrals, Cambridgeshire, UK.
authors.forename: David
authors.initials: D
authors.lastname: Donaldson
authors.affiliation: Sydney Eye Hospital, University of Sydney, Sydney, NSW, Australia.
authors.forename: Francis A
authors.initials: FA
authors.lastname: Billson
authors.affiliation: Ophthalmology Department, Small Animal Specialist Hospital, North Ryde, NSW, Australia.
authors.forename: F Mark
authors.initials: FM
authors.lastname: Billson
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs; D005901:Glaucoma / Q000628:therapy / Q000662:veterinary*; D020327:Glaucoma Drainage Implants / Q000662:veterinary*; D006801:Humans; D007429:Intraocular Pressure; D015814:Ocular Hypotension / Q000517:prevention & control / Q000662:veterinary*; D011183:Postoperative Complications / Q000517:prevention & control / Q000662:veterinary*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity
keywords: Baerveldt; canine; dog; glaucoma drainage device; glaucoma surgery; gonioimplant