title: Anatomy and Function of the Normal and Diseased Mitral Apparatus: Implications for Transcatheter Therapy.
abstract: Transcatheter mitral valve therapy requires an in-depth understanding of the mitral valve apparatus (annulus, leaflets, chordae tendinae, and papillary muscles) and the impact of various disease states. Adjacent structures (left atrium, left ventricular outflow tract, aortic valve, coronary sinus, and circumflex artery) must also be respected. This article reviews the anatomy and function of the normal and diseased mitral valve apparatus and the implications for catheter-based intervention.
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, University of Washington, 1959 Northeast Pacific Street, Box 356171, Seattle, WA 98195, USA. Electronic address: eperpetu@uw.edu.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Perpetua
authors.affiliation: Division of Cardiology, Department of Medicine, University of Washington, 1959 Northeast Pacific Street, Box 356171, Seattle, WA, USA.
authors.forename: Dmitry B
authors.initials: DB
authors.lastname: Levin
authors.affiliation: Division of Cardiology, Department of Medicine, University of Washington, 1959 Northeast Pacific Street, Box 356171, Seattle, WA, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Reisman
mesh_terms: D001021:Aortic Valve; D002815:Chordae Tendineae; D004452:Echocardiography; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000628:therapy*; D010210:Papillary Muscles; D016277:Ventricular Function, Left
keywords: Catheter-based intervention; Mitral valve; Mitral valve apparatus; Transcatheter valve therapy