title: Nasal High-Flow Therapy for Preterm Infants: Review of Neonatal Trial Data.
abstract: Heated, humidified, nasal high-flow (HF) therapy is a promising treatment for preterm infants, and almost certainly has a place in the clinical care of this population. It is only in the last few years that data have become available from randomized trials comparing HF with other noninvasive respiratory support modes, particularly nasal continuous positive airway pressure. This article discusses the evidence for HF use from randomized clinical trials in preterm infants and proposes recommendations for evidence-based practice.
authors.affiliation: Neonatal Services, Newborn Research Centre, The Royal Women's Hospital, Level 7, 20 Flemington Road, Parkville, Victoria 3052, Australia; Department of Obstetrics and Gynaecology, The University of Melbourne, Level 7, 20 Flemington Road, Parkville, Victoria 3052, Australia. Electronic address: brett.manley@thewomens.org.au.
authors.forename: Brett J
authors.initials: BJ
authors.lastname: Manley
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000453:epidemiology; D000072601:Cannula; D002986:Clinical Trials as Topic; D045422:Continuous Positive Airway Pressure / Q000379:methods*; D019317:Evidence-Based Medicine; D006801:Humans; D062071:Infant, Extremely Premature; D007231:Infant, Newborn; D063087:Noninvasive Ventilation / Q000379:methods*; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*
keywords: Continuous positive airway pressure; Infant, premature; Intensive care, neonatal; Respiratory distress syndrome, newborn