title: Hydroxyapatite Nanowires@Metal-Organic Framework Core/Shell Nanofibers: Templated Synthesis, Peroxidase-Like Activity, and Derived Flexible Recyclable Test Paper.
abstract: The templated synthesis of hydroxyapatite (HAP) nanowires@metal-organic framework (MOF) core/shell nanofibers (named HAP@MIL-100(Fe) nanofibers) is demonstrated. The ultralong hydroxyapatite nanowires are adopted as a hard template for the nucleation and growth of MIL-100(Fe) (a typical MOF) through the layer-by-layer method. The Coulombic and chelation interactions between Ca2+ions on the surface of the HAP nanowires and the COO-organic linkers of MIL-100(Fe) play key roles in the formation process. The as-prepared, water-stable HAP@MIL-100(Fe) nanofibers exhibit peroxidase-like activity toward the oxidation of different peroxidase substrates in the presence of H2O2, accompanied by a clear color change of the solution. Furthermore, a flexible, recyclable HAP@MIL-100(Fe) test paper is prepared successfully by using HAP@MIL-100(Fe) nanofibers as building blocks. A simple, low-cost, and sensitive colorimetric method for the detection of H2O2and glucose is established based on the as-prepared, flexible, recyclable HAP@MIL-100(Fe) test paper. More importantly, the HAP@MIL-100(Fe) test paper can be recovered easily for reuse by simply dipping in absolute ethanol for just 30 min, thus showing excellent recyclability. With its combination of advantages such as easy transportation, easy storage and use, rapid recyclability, light weight, and high flexibility, this HAP@MIL-100(Fe) test paper is promising for wide applications in various fields.
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P.R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P.R. China.
authors.forename: Fei-Fei
authors.initials: FF
authors.lastname: Chen
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P.R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P.R. China.
authors.forename: Ying-Jie
authors.initials: YJ
authors.lastname: Zhu
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P.R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P.R. China.
authors.forename: Zhi-Chao
authors.initials: ZC
authors.lastname: Xiong
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P.R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P.R. China.
authors.forename: Tuan-Wei
authors.initials: TW
authors.lastname: Sun
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis; D001681:Biological Assay / Q000379:methods; D002118:Calcium / Q000737:chemistry; D017886:Durapatite / Q000737:chemistry*; D005947:Glucose / Q000032:analysis; D006861:Hydrogen Peroxide / Q000032:analysis; D000073396:Metal-Organic Frameworks / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry*; D053770:Nanowires / Q000737:chemistry*; D010084:Oxidation-Reduction; D010316:Particle Size; D009195:Peroxidase / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013499:Surface Properties; D013818:Thermogravimetry / Q000379:methods; D014867:Water / Q000737:chemistry
chemical_list: D000073396:Metal-Organic Frameworks; D014867:Water; D017886:Durapatite; D006861:Hydrogen Peroxide; D009195:Peroxidase; D005947:Glucose; D001205:Ascorbic Acid; D002118:Calcium
keywords: biosensors; enzymes; hydroxyapatite; metal-organic frameworks; nanowires; test papers