title: Endoscopic ultrasound in the diagnosis of acinar cell carcinoma of the pancreas: contrast-enhanced endoscopic ultrasound, endoscopic ultrasound elastography, and pathological correlation.
abstract: We report a case series of five patients with pancreatic acinar cell carcinoma who received surgical treatment and compared the preoperative contrast-enhanced endoscopic ultrasound (EUS) and EUS elastography patterns with the surgical specimens. The contrast-enhanced EUS indicated vascular tumors with gradual enhancement in four patients and a hypovascular tumor in one patient. The elastography indicated an elastic score of 3 (hard lesion with softer border) in two patients and a score of 5 (hard lesion, which included the surrounding area) in two patients. In tumors with an elastic score of 5, the pathology exhibited abundant hyalinizing fibrous stroma or massive tumor invasion to the surrounding tissue. We concluded that acinar cell carcinoma of the pancreas has various patterns of EUS contrast-enhancement and elastography, depending on the pathologic phenotype.
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Gastroenterology and Hepatology, Nagoya, Japan; Police General Hospital, Department of Internal Medicine, Bangkok, Thailand.
authors.forename: Tanyaporn
authors.initials: T
authors.lastname: Chantarojanasiri
authors.affiliation: Nagoya University Hospital - Department of Endoscopy, Nagoya, Japan.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Hirooka
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Gastroenterology and Hepatology, Nagoya, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Kawashima
authors.affiliation: Nagoya University Hospital - Department of Endoscopy, Nagoya, Japan.
authors.forename: Eizaburo
authors.initials: E
authors.lastname: Ohno
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Gastroenterology and Hepatology, Nagoya, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamamura
authors.affiliation: Nagoya University Hospital - Department of Endoscopy, Nagoya, Japan.
authors.forename: Kohei
authors.initials: K
authors.lastname: Funasaka
authors.affiliation: Nagoya University Graduate School of Medicine - Division of Therapeutic Medicine, Department of Internal Medicine, Nagoya, Japan.
authors.forename: Masanao
authors.initials: M
authors.lastname: Nakamura
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Gastroenterology, Nagoya, Japan.
authors.forename: Ryoji
authors.initials: R
authors.lastname: Miyahara
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Gastroenterology and Hepatology, Nagoya, Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Ishigami
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Gastroenterology, Nagoya, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Watanabe
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Pathology and Clinical Laboratories, Nagoya, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Nakaguro
authors.affiliation: Nagoya University Hospital - Department of Pathology and Clinical Laboratories, Nagoya, Japan.
authors.forename: Yoshie
authors.initials: Y
authors.lastname: Shimoyama
authors.affiliation: Nagoya University Hospital - Department of Pathology and Clinical Laboratories, Nagoya, Japan.
authors.forename: Shigeo
authors.initials: S
authors.lastname: Nakamura
authors.affiliation: Nagoya University Graduate School of Medicine - Department of Gastroenterology, Nagoya, Japan.
authors.forename: Hidemi
authors.initials: H
authors.lastname: Goto