title: Clinical differences between cocaine-dependent patients with and without antisocial personality disorder.
abstract: The aim of this study is to compare the features of two groups of cocaine dependent patients in treatment, one of them with co-morbid diagnosis of antisocial personality disorder and the other not. Cross-sectional design, with 143 cocaine-dependent patients attending a drug unit, distributed in two groups: patients with and without Antisocial Personality Disorder. As results, we found that the 15.38% of the sample were diagnosed with an Antisocial Personality Disorder. In relation to socio-demographic variables, Antisocial Personality Disorder patients have less probability of being working or studying (9.1% vs. 47.9%). After multivariate analysis it was found that significantly Antisocial Personality Disorder patients have more opiates dependence (OR: 0.219; 95% IC 0.072-0.660), sedative dependence (OR: 0.203; 95% IC 0.062-0.644) and in more cases show Borderline Personality Disorder (OR: 0.239; 95% IC 0.077-0.746). This study highlights significant differences between cocaine addicts with or without an Antisocial Personality Disorder. All these differences are good indicators of the complexity of the patients with this personality disorder. Better knowledge of their profile will help us to improve the design of specific treatment programs.
authors.affiliation: Addiction and Dual Diagnosis Unit, Psychiatry Department, Vall Hebron Hospital-ASPB, Universitat Autònoma de Barcelona, CIBERSAM, Spain; Department of Psychiatry, Hospital Universitari Vall d'Hebron, CIBERSAM, Universitat Autònoma de Barcelona, Spain. Electronic address: mcomin@vhebron.net.
authors.forename: Marina
authors.initials: M
authors.lastname: Comín
authors.affiliation: Department of Personality, Assessment and Psychological Treatment, Universitat de Barcelona, Spain.
authors.forename: Santiago
authors.initials: S
authors.lastname: Redondo
authors.affiliation: Addiction and Dual Diagnosis Unit, Psychiatry Department, Vall Hebron Hospital-ASPB, Universitat Autònoma de Barcelona, CIBERSAM, Spain.
authors.forename: Constanza
authors.initials: C
authors.lastname: Daigre
authors.affiliation: Addiction and Dual Diagnosis Unit, Psychiatry Department, Vall Hebron Hospital-ASPB, Universitat Autònoma de Barcelona, CIBERSAM, Spain; Department of Psychiatry, Hospital Universitari Vall d'Hebron, CIBERSAM, Universitat Autònoma de Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Spain.
authors.forename: Lara
authors.initials: L
authors.lastname: Grau-López
authors.affiliation: Department of Psychiatry, Hospital Universitari Vall d'Hebron, CIBERSAM, Universitat Autònoma de Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Casas
authors.affiliation: Addiction and Dual Diagnosis Unit, Psychiatry Department, Vall Hebron Hospital-ASPB, Universitat Autònoma de Barcelona, CIBERSAM, Spain; Department of Psychiatry, Hospital Universitari Vall d'Hebron, CIBERSAM, Universitat Autònoma de Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Roncero
mesh_terms: D000328:Adult; D000987:Antisocial Personality Disorder / Q000150:complications / Q000175:diagnosis* / Q000523:psychology; D019970:Cocaine-Related Disorders / Q000150:complications / Q000175:diagnosis* / Q000523:psychology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D009293:Opioid-Related Disorders / Q000150:complications / Q000175:diagnosis* / Q000523:psychology; D063189:Symptom Assessment
keywords: Addiction; Addiction severity; Antisocial personality disorder; Cocaine dependence; Dual diagnosis; PRISM