title: Choroidal thickness in older patients with central serous chorioretinopathy.
abstract: BACKGROUND
  To investigate the choroidal thickness in older patients with central serous chorioretinopathy (CSCR) compared to age-matched normal subjects.
  
  
  METHODS
  Fifteen patients (30 eyes) with CSCR, all aged ≥60 years, and 21 age-matched normal subjects (21 eyes) underwent high-definition raster scanning using SD-OCT. Both eyes from CSCR patients were included in the analysis. The eyes in patients with CSCR were divided into two groups: active CSCR (17 eyes) if there was foveal-involving subretinal fluid and inactive contralateral eye group (13 eyes). Choroidal thickness was measured from the posterior edge of the retinal pigment epithelium to the choroidal-scleral junction at 500 µm intervals up to 2500 µm temporal and nasal to the fovea (11 locations).
  
  
  RESULTS
  The mean age of the patients with CSCR was 68.87 ± 6.83 years (mean ± standard deviation). Reliable measurements of choroidal thickness were obtainable in 70.6 % of eyes examined. The choroid was statistically significantly thicker in eyes with both active CSCR (P< 0.001) and inactive contralateral eyes (P< 0.01) when compared to normal age-matched eyes. The subfoveal choroid was 95 µm (P< 0.01) thicker in eyes with active CSCR (338.05 ± 31.42 µm) compared with normal eyes (243.05 ± 13.39 µm). The subfoveal choroid thickness in the inactive contralateral eyes was numerically greater than normal, and it was not statistically significantly thicker compared to the normal eyes (difference-55.68 µm,P> 0.05).
  
  
  CONCLUSIONS
  Choroid in older patients with active CSCR was thicker than the choroid in age-matched normal eyes. It is important to consider CSCR as a differential diagnosis of serous retinal detachment in elderly patients with thickened choroid and to consider SD-OCT as an imaging modality by which to evaluate the choroidal thickness.
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA ; Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: Caio V
authors.initials: CV
authors.lastname: Regatieri
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA ; Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: Eduardo A
authors.initials: EA
authors.lastname: Novais
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA.
authors.forename: Lauren
authors.initials: L
authors.lastname: Branchini
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA.
authors.forename: Mehreen
authors.initials: M
authors.lastname: Adhi
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA.
authors.forename: Emily D
authors.initials: ED
authors.lastname: Cole
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA ; Department of Ophthalmology, Federal University of Goiás, Goiânia, Brazil.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Louzada
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA ; Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
authors.forename: Mark
authors.initials: M
authors.lastname: Lane
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA.
authors.forename: Elias
authors.initials: E
authors.lastname: Reichel
authors.affiliation: New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111 USA.
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
keywords: Central serous chorioretinopathy; Choroid; Optical coherence tomography