title: Antiangiogenic resistance via metabolic symbiosis.
abstract: Several types of tumor are currently treated with antiangiogenic drugs. Unfortunately, most of these patients develop therapy resistance and succumb to the disease. Recently, a novel mechanism of resistance to antiangiogenics involving metabolic symbiosis of tumor cells has been described. Strategies to block resistance are emerging as a promising therapeutic approach.
authors.affiliation: Tumor Angiogenesis Group, ProCURE, Catalan Institute of Oncology - IDIBELL , Barcelona, Spain.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Jiménez-Valerio
authors.affiliation: Tumor Angiogenesis Group, ProCURE, Catalan Institute of Oncology - IDIBELL , Barcelona, Spain.
authors.forename: Oriol
authors.initials: O
authors.lastname: Casanovas
keywords: Angiogenesis; antiangiogenic resistance; antiangiogenic therapy; mTOR; metabolic symbiosis