title: A bioinspired iron catalyst for nitrate and perchlorate reduction.
abstract: Nitrate and perchlorate have considerable use in technology, synthetic materials, and agriculture; as a result, they have become pervasive water pollutants. Industrial strategies to chemically reduce these oxyanions often require the use of harsh conditions, but microorganisms can efficiently reduce them enzymatically. We developed an iron catalyst inspired by the active sites of nitrate reductase and (per)chlorate reductase enzymes. The catalyst features a secondary coordination sphere that aids in oxyanion deoxygenation. Upon reduction of the oxyanions, an iron(III)-oxo is formed, which in the presence of protons and electrons regenerates the catalyst and releases water.
authors.affiliation: School of Chemical Sciences, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA.
authors.forename: Courtney L
authors.initials: CL
authors.lastname: Ford
authors.affiliation: School of Chemical Sciences, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA.
authors.forename: Yun Ji
authors.initials: YJ
authors.lastname: Park
authors.affiliation: School of Chemical Sciences, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA.
authors.forename: Ellen M
authors.initials: EM
authors.lastname: Matson
authors.affiliation: School of Chemical Sciences, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA.
authors.forename: Zachary
authors.initials: Z
authors.lastname: Gordon
authors.affiliation: School of Chemical Sciences, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA. fout@illinois.edu.
authors.forename: Alison R
authors.initials: AR
authors.lastname: Fout
mesh_terms: D055162:Biocatalysis; D020134:Catalytic Domain; D007501:Iron / Q000737:chemistry*; D009565:Nitrate Reductases / Q000737:chemistry*; D009566:Nitrates / Q000737:chemistry*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000737:chemistry*; D010472:Perchlorates / Q000737:chemistry*
chemical_list: D009566:Nitrates; D010472:Perchlorates; D007501:Iron; D010088:Oxidoreductases; D009565:Nitrate Reductases; C021777:chlorate reductase; C494474:perchlorate