title: Comparison of the Analgesic Effect of Paracetamol and Magnesium Sulfate during Surgeries.
abstract: BACKGROUND
  New drugs are increasingly used to induce analgesia during surgeries. This study compared the analgesic effects of paracetamol and magnesium sulfate.
  
  
  METHODS
  Sixty patients with American Society of Anesthesiologists (ASA) class I or II patients who were candidates for surgery of the lower limbs were randomly divided into three equal groups who were age and gender matched. Group 1 received paracetamol, and group 2, the magnesium sulfate during surgery and group 3 as the control. Pain intensities were measured and recorded using the Visual Analog Scale before surgery, in the recovery room, and 6, 12, and 18 hours after surgery.
  
  
  RESULTS
  Pain intensities (7.10, 5.80, and 4.10) were higher in the control group; 6, 12, and 18 hours after surgery compared to the paracetamol (6.45, 4.15, 2.50) and the magnesium groups (7.25, 4.55, and 2.05), but the difference was not statistically significant.
  
  
  CONCLUSIONS
  Paracetamol and magnesium sulfate were shown to have postoperative analgesic effects and reduce the quantity of narcotic use after surgery.
authors.affiliation: Medical Ethic Research Center, Jahrom University of Medical Sciences, Jahrom, Iran;; Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran.
authors.forename: Navid
authors.initials: N
authors.lastname: Kalani
authors.affiliation: Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran;; Research Center For Social Determinants Of Health, Jahrom University of Medical Sciences, Jahrom, Iran.
authors.forename: Mohammad Sadegh
authors.initials: MS
authors.lastname: Sanie
authors.affiliation: Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran.
authors.forename: Hasan
authors.initials: H
authors.lastname: Zabetian
authors.affiliation: Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Radmehr
authors.affiliation: Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Sahraei
authors.affiliation: Department of Anaesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Kargar Jahromi
authors.affiliation: Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Hadi
authors.initials: H
authors.lastname: Zare Marzouni
keywords: Analgesia; Limb; Magnesium sulphate; Pain; Paracetamol