title: Intensive enhanced cognitive behavioural therapy for severe and enduring anorexia nervosa: A longitudinal outcome study.
abstract: This study aimed to evaluate short- and long-term outcomes in patients with severe and enduring anorexia nervosa (SE-AN), as compared with those with non SE-AN (NSE-AN), both treated via an inpatient programme based on a "recovery model" approach.
  
  
  
  Sixty-six adult patients with anorexia nervosa (AN) were recruited from among consecutive referrals to a community-based eating disorder clinic offering inpatient enhanced cognitive behavioural therapy for eating disorders (CBT-E). Body mass index (BMI), and Eating Disorder Examination (EDE) and Brief Symptom Inventory (BSI) scores were recorded at admission, at the end of treatment, and at 6- and 12-month follow-ups.
  
  
  
  Thirty-two patients (48.5%) were classified as SE-AN (i.e., duration of illness >7 years), and 34 (51.5%) as NSE-AN. During the treatment, both groups displayed similarly large increases in BMI, as well as improvements in eating-disorder and general psychopathology. After discharge minor deterioration did occur, but both NSE-AN and SE-AN groups showed similar rates of 'good BMI outcome' (BM ≥ 18.5; 44.0% and 40.7%, respectively) and 'full response' (BMI ≥ 18.5 and minimal eating-disorder psychopathology; 32.0% and 33.3%, respectively) at 12-month follow-up.
  
  
  
  These findings suggest that inpatient CBT-E is well accepted by patients with AN, and could also be a viable and promising treatment for those with SE-AN.
authors.affiliation: Department of Eating and Weight Disorders, Villa Garda Hospital, Via Montebaldo, 89, I-37016, Garda, VR, Italy. Electronic address: si.calugi@gmail.com.
authors.forename: Simona
authors.initials: S
authors.lastname: Calugi
authors.affiliation: Department of Eating and Weight Disorders, Villa Garda Hospital, Via Montebaldo, 89, I-37016, Garda, VR, Italy.
authors.forename: Marwan
authors.initials: M
authors.lastname: El Ghoch
authors.affiliation: Department of Eating and Weight Disorders, Villa Garda Hospital, Via Montebaldo, 89, I-37016, Garda, VR, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Dalle Grave
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000628:therapy*; D016022:Case-Control Studies; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D007297:Inpatients / Q000523:psychology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: Cognitive behavioural therapy; Disease duration; Duration of illness; Inpatient treatment; Severe and enduring anorexia nervosa