title: Dietary linseed oil in the maternal diet affects immunoglobulins, tissue fatty acid composition and expression of lipid metabolism-related genes in piglets.
abstract: This experiment investigated the effects of supplementing the maternal diet with linseed oil (LSO) and soya bean oil (SBO) on immunoglobulins, the fatty acid composition and hepatic expression of lipid metabolism-related genes in piglets. Multiparous sows (twenty-four per diet) were fed on diets containing a supplement of either SBO or LSO during last week of gestation and lactation. The results indicated that supplementation of maternal diet with LSO could improve the weaning weight of piglets and average daily gain (ADG) (p < 0.05). The concentration of immunoglobulin G (IgG) and immunoglobulin A (IgA) was enhanced in sow plasma, colostrum and milk by the addition of LSO (p < 0.05). In addition, the concentration of 18: 3n-3 fatty acids was higher in the milk of LSO sows. Meanwhile, maternal supplementation with LSO increased the levels of plasma IgG, IgA and the tissues n-3 polyunsaturated fatty acid (PUFA) in piglets (p < 0.05). Correspondingly, the mRNA expression levels of hepatic ∆5-desaturase (D5D) and ∆6-desaturase (D6D) were higher, and fatty acid synthase (FAS) was lower in piglets from LSO-fed sows when compared with that in the SBO group. In conclusion, LSO supplementation of the maternal diet increases immunoglobulins, modifies the fatty acid composition and affects the gene of D5D and D6D expression of piglets.
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: X L
authors.initials: XL
authors.lastname: Chen
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: N
authors.initials: N
authors.lastname: Wang
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: M L
authors.initials: ML
authors.lastname: Tian
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: T
authors.initials: T
authors.lastname: Liu
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: X W
authors.initials: XW
authors.lastname: Zhang
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: B M
authors.initials: BM
authors.lastname: Shi
authors.affiliation: Institute of Animal Nutrition, Northeast Agricultural University, Harbin, China.
authors.forename: A S
authors.initials: AS
authors.lastname: Shan
mesh_terms: D000821:Animal Feed / Q000032:analysis*; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D000831:Animals, Newborn; D004032:Diet / Q000662:veterinary*; D019587:Dietary Supplements; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation / Q000187:drug effects; D007136:Immunoglobulins / Q000097:blood* / Q000378:metabolism; D008043:Linseed Oil / Q000008:administration & dosage / Q000494:pharmacology*; D050356:Lipid Metabolism / Q000187:drug effects / Q000502:physiology; D011247:Pregnancy; D039401:Prenatal Nutritional Physiological Phenomena; D013552:Swine / Q000254:growth & development / Q000378:metabolism*
chemical_list: D005227:Fatty Acids; D007136:Immunoglobulins; D008043:Linseed Oil
keywords: gene expression; immunoglobulins; linseed oil; piglet; sow