title: Mandibular bone necrosis after use of paraformaldehyde-containing paste.
abstract: Paraformaldehyde has been used in the past as a pulpotomy agent. However, it has a severe cytotoxic effect and may cause alveolar bone necrosis. Depulpin, a devitalizing agent containing 49% paraformaldehyde, is no longer used frequently due to its severe side effects. In the two cases described in the present study, Depulpin was used as a devitalizing agent during root canal treatment. It caused a gradual loss of sensibility in adjacent teeth, gingival necrosis, and osteomyelitis. This case report demonstrates the serious side effects of using a paraformaldehyde-containing paste as a devitalizing agent for pulp, particularly mandibular bone necrosis.
authors.affiliation: Department of Conservative Dentistry, Wonkwang University School of Dentistry, Iksan, Korea.
authors.forename: Chi-Hwan
authors.initials: CH
authors.lastname: Lee
authors.affiliation: Department of Conservative Dentistry, Wonkwang University School of Dentistry, Iksan, Korea.
authors.forename: Yoorina
authors.initials: Y
authors.lastname: Choi
authors.affiliation: Department of Conservative Dentistry, Wonkwang University School of Dentistry, Iksan, Korea.
authors.forename: Sujung
authors.identifier: 0000-0003-3457-1242
authors.initials: S
authors.lastname: Park
keywords: Depulpin; Mandibular bone necrosis; Osteomyelitis; Paraformaldehyde