title: Long-Term Effect of Surface Roughness and Patients' Factors on Crestal Bone Loss at Dental Implants. A Systematic Review and Meta-Analysis.
abstract: Publications from 2011 to 2015 were selected to evaluate effect of implant surface roughness on long-term bone loss as surrogate for peri-implantitis risk. 87 out of 2,566 papers reported the mean bone loss after at least 5 years of function. Estimation of the proportion of implants with bone loss above 1, 2, and 3 mm as well as analysis the effect of implant surface roughness, smoking, and history of periodontitis was performed. By means of the provided statistical information of bone loss (mean and standard deviation) the prevalence of implants with bone loss ranging from 1 to 3 mm was estimated. The bone loss was used as a surrogate parameter for "peri-implantitis" given the fact that "peri-implantitis" prevalence was not reported in most studies or when reported, the diagnostic criteria were unclear or of dubious quality. The outcome of this review suggests that peri-implant bone loss around minimally rough implant systems was statistically significant less in comparison to the moderately rough and rough implant systems. No statistically significant difference was observed between moderately rough and rough implant systems. The studies that compared implants with comparable design and different surface roughness, showed less average peri-implant bone loss around the less rough surfaces in the meta-analysis. However, due to the heterogeneity of the papers and the multifactorial cause for bone loss, the impact of surface roughness alone seems rather limited and of minimal clinical importance. Irrespective of surface topography or implant brand, the average weighted implant survival rate was 97.3% after 5 years or more of loading. If considering 3 mm bone loss after at least 5 years to represent the presence of "peri-implantitis," less than 5% of the implants were affected. The meta-analysis indicated that periodontal history and smoking habits yielded more bone loss.
authors.affiliation: Specialist in training, Master student Periodontology, Department Periodontology & Oral Implantology, Dental School, Faculty Medicine and Health Sciences, Ghent University Belgium.
authors.forename: Ron
authors.initials: R
authors.lastname: Doornewaard
authors.affiliation: PhD student, Department Periodontology & Oral Implantology, Dental School, Faculty Medicine and Health Sciences, Ghent University Belgium.
authors.forename: Véronique
authors.initials: V
authors.lastname: Christiaens
authors.affiliation: full professor and chairman, Department Periodontology & Oral Implantology, Dental School, Faculty Medicine and Health Sciences, Ghent University Belgium, visiting professor, Department of Prosthodontics, Malmö University, Sweden.
authors.forename: Hugo
authors.initials: H
authors.lastname: De Bruyn
authors.affiliation: adjunct professor, Department of Prosthodontics, Malmö University, Sweden.
authors.forename: Magnus
authors.initials: M
authors.lastname: Jacobsson
authors.affiliation: professor, Department Periodontology & Oral Implantology, Dental School, Faculty Medicine and Health Sciences, Ghent University Belgium, professor, Faculty of Medicine and Health Sciences, Oral Health Research Group ORHE, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Cosyn
authors.affiliation: assistant professor, Department Periodontology & Oral Implantology, Dental School, Faculty Medicine and Health Sciences, Ghent University Belgium.
authors.forename: Stijn
authors.initials: S
authors.lastname: Vervaeke
authors.affiliation: professor, Faculty of Medicine and Pharmacy, Department of Educational Sciences EDWE-LOCI, Faculty of Psychology and Educational Sciences, Vrije Universiteit Brussel, Brussels, Belgium, professor, Faculty of Medicine and Health Sciences, Oral Health Research Group ORHE, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Jacquet
mesh_terms: D016301:Alveolar Bone Loss / Q000209:etiology*; D015921:Dental Implants / Q000009:adverse effects*; D017267:Dental Prosthesis Design; D006801:Humans; D057873:Peri-Implantitis / Q000209:etiology*; D012307:Risk Factors; D013499:Surface Properties
chemical_list: D015921:Dental Implants
keywords: bone loss; dental implant; implant survival; meta-analysis; peri-implantitis; surface roughness; surface topography; systematic review