title: Adjuvant and Neoadjuvant Therapy for Resectable Pancreatic and Periampullary Cancer.
abstract: Pancreatic adenocarcinoma is a relatively uncommon malignancy associated with a high rate of cancer-related mortality despite best efforts to perform curative surgery. Adjuvant therapy in patients after surgical resection is associated with improved overall survival. Adjuvant treatment approaches may include either chemotherapy alone or a combination of chemotherapy and radiation therapy. Neoadjuvant approaches, also including either chemotherapy alone or a combination of chemotherapy and radiation therapy, are under investigation. Periampullary cancers constitute a rare and heterogeneous group of tumors that are typically treated as pancreatic cancers given their histologic similarities and tumor location.
authors.affiliation: Division of Hematology and Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, 11100 Euclid Avenue, Lakeside 1200, Cleveland, OH 44106, USA.
authors.forename: Stephanie M
authors.initials: SM
authors.lastname: Kim
authors.affiliation: Division of Hematology and Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, 11100 Euclid Avenue, Lakeside 1200, Cleveland, OH 44106, USA. Electronic address: jennifer.eads@uhhospitals.org.
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Eads
mesh_terms: D017024:Chemotherapy, Adjuvant; D006801:Humans; D020360:Neoadjuvant Therapy; D010180:Pancreatectomy / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000628:therapy*; D018714:Radiotherapy, Adjuvant
keywords: Adjuvant; Neoadjuvant; Pancreatic adenocarcinoma; Pancreatic cancer; Periampullary cancer