title: MitraClip Therapy for Mitral Regurgitation: Primary Mitral Regurgitation.
abstract: Primary mitral regurgitation (MR) owing to degenerative changes in the structural components of the mitral valve is a common acquired valvular pathology in the elderly. Surgical correction with mitral valve repair (MVRe) or replacement (MVR) is the mainstay of therapy. A significant proportion of patients are ineligible for MVRe/MVR owing to prohibitive surgical risk from advanced age, poor ventricular function, or associated comorbidities. Percutaneous mitral valve repair techniques have been developed to fill this void. The edge-to-edge MitraClip has accrued the largest human experience. This paper reviews the available literature on the MitraClip device for treatment of primary MR.
authors.affiliation: Department of Cardiovascular Medicine, Heart & Vascular Institute, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.
authors.forename: G
authors.initials: G
authors.lastname: Athappan
authors.affiliation: Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, J2-3, Cleveland, OH 44195, USA.
authors.forename: Mohammad Qasim
authors.initials: MQ
authors.lastname: Raza
authors.affiliation: Cardiac Catheterization Laboratory, Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, J2-3, Cleveland, OH 44195, USA. Electronic address: kapadis@ccf.org.
authors.forename: Samir R
authors.initials: SR
authors.lastname: Kapadia
mesh_terms: D006348:Cardiac Surgical Procedures; D006801:Humans; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000601:surgery*
keywords: Degenerative MR; High risk; MitraClip; Mitral regurgitation; Primary MR