title: Evaluating PROMIS(®) applied cognition items in a sample of older adults at risk for cognitive decline.
abstract: PROMIS(®) Applied Cognition is a short self-assessment of cognitive abilities and concerns that eliminates the need for a trained rater and provides online question banks that can be uniformly used across health care providers. This 12-month prospective study of 281 elderly individuals evaluates self-perceptions of cognitive functioning in relation to objective cognition, or assessment by an external rater, and compares PROMIS® Applied Cognition Abilities and Concerns subsets with commonly used "legacy" instruments. PROMIS® correlated with objective legacy measures (the Mini-Mental State Examination [MMSE] and Saint Louis University Mental Status [SLUMS] examination), depression (measured with the Geriatric Depression Scale [GDS]), anxiety, and activities of daily living. PROMIS® and MMSE correlations remained after controlling for depression and anxiety. PROMIS® associated more strongly than MMSE with depression, highlighting the relationship between subjective cognitive deficit and depression. One-year changes in PROMIS® correlated with one-year changes in MMSE and GDS. The PROMIS® Abilities subset more strongly correlated with objective cognition, whereas the Concerns subset more strongly correlated with depression and activities of daily living. PROMIS® seems to be a reasonable prescreening tool to identify patients with cognitive decline or psychological distress.
authors.affiliation: Case Western Reserve University School of Medicine, 2109 Adelbert Rd, Cleveland, OH 44106, USA. Electronic address: molly.howland@case.edu.
authors.forename: Molly
authors.initials: M
authors.lastname: Howland
authors.affiliation: Neurological and Behavioral Outcomes Center, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA; Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, 2109 Adelbert Rd, Cleveland, OH 44106, USA; Department of Neurology, Case Western Reserve University School of Medicine, 2109 Adelbert Rd, Cleveland, OH 44106, USA. Electronic address: cmt66@case.edu.
authors.forename: Curtis
authors.initials: C
authors.lastname: Tatsuoka
authors.affiliation: Department of Neurology, Case Western Reserve University School of Medicine, 2109 Adelbert Rd, Cleveland, OH 44106, USA. Electronic address: kathleen.smyth@case.edu.
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Smyth
authors.affiliation: Case Western Reserve University School of Medicine, 2109 Adelbert Rd, Cleveland, OH 44106, USA; Neurological and Behavioral Outcomes Center, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA; Department of Neurology, Case Western Reserve University School of Medicine, 2109 Adelbert Rd, Cleveland, OH 44106, USA; Department of Psychiatry, Case Western Reserve University School of Medicine, 2109 Adelbert Rd, Cleveland, OH 44106, USA. Electronic address: martha.sajatovic@uhhospitals.org.
authors.forename: Martha
authors.initials: M
authors.lastname: Sajatovic
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology*; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000175:diagnosis; D003071:Cognition; D060825:Cognitive Dysfunction / Q000523:psychology*; D003863:Depression / Q000175:diagnosis; D059026:Diagnostic Self Evaluation; D005260:Female; D015577:Geriatric Assessment / Q000379:methods*; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011446:Prospective Studies; D012649:Self Concept
keywords: Activities of daily living; Anxiety; Dementia; Depression; Geriatric assessment; Mild cognitive impairment; Self report