title: [Technological Set-up of Epiretinal Implants].
abstract: In blinded patients, visual prostheses can restore visual perception by appropriate electrical stimulation of retinal nerve cells. This article presents the basic technological principles of retinal prostheses, using an epiretinal implantable visual prosthesis as example. An implantable visual prosthesis typically consists of extraocular and intraocular sections. The extraocular section is responsible for detecting the image. The information is derived from this image that is needed for appropriate electrical stimulation of the retinal nerve cells. Together with the necessary energy, these data are transmitted through a magnetic connection to the intraocular section. To ensure reliable transmission, the data are encoded. After transmission, energy and data are separated in the intraocular section, and the data are decoded. In accordance with the transmitted information, biphasic pulses of defined intensity and duration are produced on the simulation electrodes. In this way, ganglia cells are electrically stimulated and react with action potentials, which are transmitted to the visual cortex, where they lead to visual perception.
authors.affiliation: Institut für Werkstoffe der Elektrotechnik I, Rheinisch-Westfälische Technische Hochschule Aachen.
authors.forename: W
authors.initials: W
authors.lastname: Mokwa
authors.affiliation: Mikro- und Nanosysteme, Fraunhofer-Institut für Mikroelektronische Schaltungen und Systeme, Duisburg.
authors.forename: M
authors.initials: M
authors.lastname: Görtz
mesh_terms: D000818:Animals; D001766:Blindness / Q000209:etiology / Q000534:rehabilitation*; D004599:Electric Stimulation Therapy / Q000295:instrumentation* / Q000379:methods; D004567:Electrodes, Implanted; D004867:Equipment Design; D019317:Evidence-Based Medicine; D006801:Humans; D019919:Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D013673:Technology Assessment, Biomedical; D013813:Therapy, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D016896:Treatment Outcome; D057488:Visual Prosthesis