title: Autofluorescence imaging bronchoscopy as a novel approach to the management of tracheobronchopathia osteochondroplastica: a case report.
abstract: Tracheobronchopathia osteochondroplastica (TO) is not only rare but also presents highly varied and unpredictable clinical manifestations. Consequently, the management and treatment strategies remain unclear. An accurate evaluation tool is important for the management of individual patients in the absence of standard guidelines. Although bronchoscopy is the gold standard for diagnosis, it cannot satisfactorily detect the treatment response and disease progression because subtle mucosal changes can go undetected. Therefore, improved techniques that can detect subtle mucosal changes associated with TO are desirable. Autofluorescence imaging bronchoscopy (AFI) is a recently introduced advanced endoscopic technology that can detect subtle mucosal changes with the aid of different colors. Here we report the first case, to the best of our knowledge, involving a 42-year-old man with TO in whom tracheal involvement was evaluated by AFI and detected as the appearance of a magenta color.
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ihara
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Tajima
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Hitomi
authors.initials: H
authors.lastname: Yoshikawa
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Tajima
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Norihiro
authors.initials: N
authors.lastname: Harada
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Fumiyuki
authors.initials: F
authors.lastname: Takahashi
authors.affiliation: Department of Pathology, Labor Health and Welfare Organization Kanto Rosai Hospital, Kawasaki, Japan.
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Uekusa
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Tetsutaro
authors.initials: T
authors.lastname: Nagaoka
authors.affiliation: Department of Respiratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan;; Research Institute for Diseases of Old Ages, Juntendo University, Faculty of Medicine, Tokyo, Japan.
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Takahashi
keywords: Tracheobronchopathia osteochondroplastica (TO); autofluorescence imaging bronchoscopy (AFI); squamous metaplasia