title: Concerted Genetic Function in Blood Traits.
abstract: The hematopoietic system plays a major role in human health. Two studies by Astle et al. and Chen et al. published in this issue of Cell use genome-wide association and functional genomics approaches to provide deep insights into the role of genetic variants in hematological traits. We discuss these discoveries and future strategies toward completing our understanding of the genetic basis for variation in human traits.
authors.affiliation: New York Genome Center, New York, NY 10013, USA; Department of Systems Biology, Columbia University, New York, NY 10027, USA.
authors.forename: Sarah
authors.initials: S
authors.lastname: Kim-Hellmuth
authors.affiliation: New York Genome Center, New York, NY 10013, USA; Department of Systems Biology, Columbia University, New York, NY 10027, USA. Electronic address: tlappalainen@nygenome.org.
authors.forename: Tuuli
authors.initials: T
authors.lastname: Lappalainen
mesh_terms: D006801:Humans; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D055106:Genome-Wide Association Study; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide