title: [Parathyroid disease: The full spectrum, from adenoma to carcinoma. Report of 3 cases].
abstract: BACKGROUND
  Primary hyperparathyroidism is a disease characterised by the autonomous production of parathyroid hormone. The most common cause is an adenoma, followed by hyperplasia, and rarely carcinoma.
  
  
  METHODS
  Three cases are presented. The first case is associated with a brown tumour that was diagnosed as hyperplasia after study and surgery. The second case was related to pathological fractures, and a lower right adenoma 236 times bigger than a normal parathyroid was excised. The last case presented with abdominal pain and heartburn. Histopathology reported a carcinoma, which was removed using surgery en bloc. All patients have improved.
  
  
  CONCLUSIONS
  Hyperparathyroidism symptoms are very difficult to identify and diagnose, thus a detailed and broad approach is needed when hyperparathyroidism is suspected.
authors.affiliation: Cirugía endocrina, Centro Médico ABC, Ciudad de México, México.
authors.forename: Enrique
authors.initials: E
authors.lastname: Stoopen-Margain
authors.affiliation: Cirugía general, Centro Médico ABC, Ciudad de México, México.
authors.forename: Sofía
authors.initials: S
authors.lastname: Valanci-Aroesty
authors.affiliation: Cirugía general, Centro Médico ABC, Ciudad de México, México.
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Castañeda-Martínez
authors.affiliation: Anatomía patológica, Centro Médico ABC, Ciudad de México, México.
authors.forename: Javier
authors.initials: J
authors.lastname: Baquera-Heredia
authors.affiliation: Cirugía general, Centro Médico ABC, Ciudad de México, México. Electronic address: jcsainz@me.com.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Sainz-Hernández
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000368:Aged; D002277:Carcinoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000209:etiology*; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D010279:Parathyroid Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D010280:Parathyroid Glands / Q000473:pathology*; D010282:Parathyroid Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D016105:Parathyroidectomy; D012086:Reoperation; D013965:Thyroidectomy; D055815:Young Adult
keywords: Adenoma paratiroideo; Carcinoma paratiroideo; Hiperplasia paratiroidea; Parathyroid; Parathyroid adenoma; Parathyroid carcinoma; Parathyroid hyperplasia; Paratiroides