title: Management of Hermansky-Pudlak syndrome in pregnancy and review of literature.
abstract: We report on the obstetric outcome of a woman aged 27 years with Hermansky-Pudlak syndrome (HPS). She underwent a caesarean section after failed induction of labour. Platelet transfusion was administered in a set schedule for 36 hours, starting 2 hours before delivery. The child had good Apgar scores and there were no significant problems of prolonged bleeding during the procedure. 72 hours postpartum, a haematoma developed at the site of the wound, subsequently complicated by a secondary infection for which she received antibiotics. Wound care was provided in an outpatient setting during 2 weeks, in which the infection stabilised and responded to the treatment. Mother and child could leave the hospital after 6 days.
authors.affiliation: Universiteit Antwerpen Faculteit geneeskunde en gezondheidswetenschappen, Wilrijk, Belgium.
authors.forename: Freya
authors.initials: F
authors.lastname: Van Avermaete
authors.affiliation: University Hospital Antwerp, Antwerp, Belgium.
authors.forename: Joke
authors.initials: J
authors.lastname: Muys
authors.affiliation: Department of Obstetrics, UZA, Edegem, Belgium.
authors.forename: Yves
authors.initials: Y
authors.lastname: Jacquemyn
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001034:Apgar Score; D002585:Cesarean Section; D019468:Disease Management; D005260:Female; D006406:Hematoma; D022861:Hermanski-Pudlak Syndrome / Q000150:complications* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007239:Infections / Q000150:complications / Q000188:drug therapy; D007751:Labor, Induced; D017713:Platelet Transfusion; D049590:Postpartum Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011250:Pregnancy Complications, Hematologic / Q000517:prevention & control; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents