title: Does a different dose of gamma irradiation have the same effect on five different types of tendon allografts? - a biomechanical study.
abstract: The goals of our study were to evaluate the biomechanical differences between five tendons and the changes in biomechanical properties caused by irradiation.
  
  
  
  Achilles, quadriceps, semitendinosus + gracilis (STG), tibialis anterior (TA) and the peroneus longus (PL) were harvested from 30 donors. Group A contained 50 tendons without gamma irradiation. The groups were irradiated with a dose of 21 kGy (group B 50 tendons) and with a dose of 42 kGy (group C 50 tendons). The grafts were soaked in a radio-protectant solution and frozen at -80 °C. Cyclic loading tests were performed followed by load to failure tests. Young modulus of elasticity, maximum force, strain at tensile strength and strain at rupture were calculated.
  
  
  
  The Achilles tendons had significantly lower Young modulus than the TA (p = 0.0036) in group A. The Achilles showed significantly lower than PL (p = 0.000042) and TA (p = 0.00142) in group B and C. The quadriceps and the ST (p = 0.0037) provided poorer values than the TA (p = 0.0432) in group C. We found no difference in maximum loads among the tendons in group A. The maximum load of the Achilles and quadriceps showed better results than the PL (p = 0.0016), (p = 0.0018) and the STG (p = 0.0066), (p = 0.0019) in group C. The TA had similar results like the Achilles and quadriceps.
  
  
  
  The vulnerability of gamma irradiation of TA was less than Achilles and quadriceps tendons.
authors.affiliation: Department of Orthopedics and Traumatology, Uzsoki Hospital, Uzsoki Street 29-41, 1145, Budapest, Hungary.
authors.forename: Gyorgy
authors.initials: G
authors.lastname: Hangody
authors.affiliation: Cooperation Research Center for Biomechanics, Budapest University of Technology and Economics, Bertalan Lajos Street 2, 1111, Budapest, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Szebényi
authors.affiliation: Department of Orthopedics and Traumatology, Uzsoki Hospital, Uzsoki Street 29-41, 1145, Budapest, Hungary.
authors.forename: Bence
authors.initials: B
authors.lastname: Abonyi
authors.affiliation: Cooperation Research Center for Biomechanics, Budapest University of Technology and Economics, Bertalan Lajos Street 2, 1111, Budapest, Hungary.
authors.forename: Rita
authors.initials: R
authors.lastname: Kiss
authors.affiliation: Department of Orthopedics and Traumatology, Uzsoki Hospital, Uzsoki Street 29-41, 1145, Budapest, Hungary.|Department of Traumatology, Semmelweis University, Uzsoki Street 29-41, 1145, Budapest, Hungary.
authors.forename: László
authors.initials: L
authors.lastname: Hangody
authors.affiliation: Department of Orthopedics and Traumatology, Uzsoki Hospital, Uzsoki Street 29-41, 1145, Budapest, Hungary. drpapster@gmail.com.|Department of Traumatology, Semmelweis University, Uzsoki Street 29-41, 1145, Budapest, Hungary. drpapster@gmail.com.
authors.forename: Károly
authors.initials: K
authors.lastname: Pap
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D064591:Allografts / Q000528:radiation effects*; D001696:Biomechanical Phenomena; D002102:Cadaver; D004548:Elasticity; D005720:Gamma Rays / Q000009:adverse effects*; D006801:Humans; D018482:Muscle, Skeletal; D013710:Tendons / Q000528:radiation effects* / Q000637:transplantation; D013718:Tensile Strength; D014019:Tissue Donors; D014184:Transplantation, Homologous
keywords: Allograft tendon; Biomechanical testing; Cryopreserving; Gamma irradiation