title: Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference.
abstract: The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that 'repigmentation' and 'maintenance of gained repigmentation' are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e-surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.
authors.affiliation: National Skin Centre, Singapore City, Singapore.
authors.forename: Emily Y
authors.initials: EY
authors.lastname: Gan
authors.affiliation: Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, UK.
authors.forename: Viktoria
authors.initials: V
authors.lastname: Eleftheriadou
authors.affiliation: Dermatology Department, Cairo University, Cairo, Egypt.
authors.forename: Samia
authors.initials: S
authors.lastname: Esmat
authors.affiliation: Multicultural Dermatology Center, Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.
authors.forename: Iltefat
authors.initials: I
authors.lastname: Hamzavi
authors.affiliation: Department of Dermatology, University Hospital of Nice, Nice, France.|INSERM U1065, Team 12, C3M, Nice, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Passeron
authors.affiliation: Department of Dermatology, University of Münster, Münster, Germany.
authors.forename: Markus
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authors.lastname: Böhm
authors.affiliation: Dermatology Department, Minia University, Minia, Egypt.
authors.forename: Tag
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authors.lastname: Anbar
authors.affiliation: Skin Physicians, Mount Elizabeth Medical Center, Singapore City, Singapore.
authors.forename: Boon Kee
authors.initials: BK
authors.lastname: Goh
authors.affiliation: Department of Dermatology, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Cheng-Che E
authors.initials: CE
authors.lastname: Lan
authors.affiliation: Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.|Photomedicine Institute, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
authors.forename: Harvey
authors.initials: H
authors.lastname: Lui
authors.affiliation: Department of Dermatology & Venereology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: M
authors.initials: M
authors.lastname: Ramam
authors.affiliation: Suite 202, Westville Hospital, Westville, South Africa.
authors.forename: Noufal
authors.initials: N
authors.lastname: Raboobee
authors.affiliation: Department of Dermatology Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Katayama
authors.affiliation: Department of Dermatology, Faculty of Medicine, Yamagata University, Yamagata, Japan.
authors.forename: Tamio
authors.initials: T
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authors.affiliation: Department of Dermatology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
authors.forename: Davinder
authors.initials: D
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authors.affiliation: Department of Dermatology, Newton Wellesley Hospital, Newton, MA, USA.
authors.forename: Vaneeta
authors.initials: V
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authors.affiliation: Multicultural Dermatology Center, Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.
authors.forename: Henry W
authors.initials: HW
authors.lastname: Lim
authors.affiliation: Department of Dermatology, Ghent University Hospital, Ghent, Belgium.
authors.forename: Nanja
authors.initials: N
authors.lastname: van Geel
authors.affiliation: National Center for Vitiligo and Psoriasis, Riyadh, Saudi Arabia.|Mulekar Clinic, Mumbai, India.
authors.forename: Sanjeev
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authors.lastname: Mulekar
authors.affiliation: Division of Dermatology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
authors.forename: John
authors.initials: J
authors.lastname: Harris
authors.affiliation: Department of Dermatology, University of New South Wales, Sydney, NSW, Australia.|Skin and Cancer Foundation, Darlinghurst, NSW, Australia.|Beecroft Dermatology, Beecroft, Sydney, NSW, Australia.
authors.forename: Richard
authors.initials: R
authors.lastname: Wittal
authors.affiliation: Mohammed V University in Rabat, Department of Dermatology, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Laila
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authors.lastname: Benzekri
authors.affiliation: Pigmentary Disorders Outpatient Clinic, Bordeaux, France.
authors.forename: Yvon
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authors.lastname: Gauthier
authors.affiliation: Department of Dermatology, Fiona Stanley Hospital and University of Western Australia, Perth, WA, Australia.
authors.forename: Prasad
authors.initials: P
authors.lastname: Kumarasinghe
authors.affiliation: National Skin Centre, Singapore City, Singapore.
authors.forename: Steven T G
authors.initials: ST
authors.lastname: Thng
authors.affiliation: Department of Dermatology, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
authors.forename: Caio Cesar
authors.initials: CC
authors.lastname: Silva de Castro
authors.affiliation: Dermatology, Andrology & Venereology Department, Ain Shams University, Cairo, Egypt.
authors.forename: Marwa
authors.initials: M
authors.lastname: Abdallah
authors.affiliation: Department of Dermatology, Academic Medical Centre, Netherlands Institute for Pigment Disorders, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Vrijman
authors.affiliation: Department of Dermatology, Academic Medical Centre, Netherlands Institute for Pigment Disorders, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Marcel
authors.initials: M
authors.lastname: Bekkenk
authors.affiliation: Department of Dermatology and Pediatric Dermatology, Bordeaux University Hospitals, Bordeaux, France.|INSERM U 1035, University of Bordeaux, Bordeaux, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Seneschal
authors.affiliation: Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Amit G
authors.initials: AG
authors.lastname: Pandya
authors.affiliation: Department of Dermatology, Hôpital Henri Mondor, Créteil, France.|EA EpiDermE (Epidémiologie en Dermatologie et Evaluation des Thérapeutiques), Université Paris-Est Créteil, Créteil, France.
authors.forename: Khaled
authors.initials: K
authors.lastname: Ezzedine
authors.affiliation: Cutaneous pathophysiology, San Gallicano Dermatologic Institute IRCCS, Rome, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Picardo
authors.affiliation: Department of Dermatology and Pediatric Dermatology, Bordeaux University Hospitals, Bordeaux, France.|INSERM U 1035, University of Bordeaux, Bordeaux, France.
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authors.initials: A
authors.lastname: Taïeb
mesh_terms: D003226:Congresses as Topic; D032921:Consensus; D006801:Humans; D012880:Skin Pigmentation; D016896:Treatment Outcome; D014820:Vitiligo / Q000628:therapy*
keywords: outcome measure; pigment; repigmentation; repigmentation pattern; vitiligo