title: Using a Redox Modality to Connect Synthetic Biology to Electronics: Hydrogel-Based Chemo-Electro Signal Transduction for Molecular Communication.
abstract: A hydrogel-based dual film coating is electrofabricated for transducing bio-relevant chemical information into electronical output. The outer film has a synthetic biology construct that recognizes an external molecular signal and transduces this input into the expression of an enzyme that converts redox-inactive substrate into a redox-active intermediate, which is detected through an amplification mechanism of the inner redox-capacitor film.
authors.affiliation: Institute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA.
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
authors.forename: Chen-Yu
authors.initials: CY
authors.lastname: Tsao
authors.affiliation: Institute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA.
authors.forename: Eunkyoung
authors.initials: E
authors.lastname: Kim
authors.affiliation: Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
authors.forename: Tanya
authors.initials: T
authors.lastname: Tschirhart
authors.affiliation: Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Terrell
authors.affiliation: Institute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA.|Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
authors.forename: William E
authors.initials: WE
authors.lastname: Bentley
authors.affiliation: Institute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD, 20742, USA.|Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
authors.forename: Gregory F
authors.initials: GF
authors.lastname: Payne
mesh_terms: D004581:Electronics; D020100:Hydrogels / Q000737:chemistry*; D008567:Membranes, Artificial; D010084:Oxidation-Reduction; D058615:Synthetic Biology
chemical_list: D020100:Hydrogels; D008567:Membranes, Artificial
keywords: electrodeposition; hydrogels; molecular communication; redox; synthetic biology