title: Drug Toxicities of Common Analgesic Medications in the Emergency Department.
abstract: About 75% of patients present to the emergency department with a complaint of pain. There are multiple prescribed and over-the-counter medications that are available for the treatment of pain. Acetaminophen, opioids, and aspirin are commonly used agents that are available as single agents or in combination with other medications. However, all of these agents are susceptible to toxic overdose, which requires prompt recognition through clinical and laboratory assessment modalities and initiation of therapy to reduce the risk of morbidity and mortality.
authors.affiliation: Department of Emergency Medicine, Wayne State University School of Medicine, 4201 St. Antoine, 6F UHC, Detroit, MI 48201, USA.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Ciejka
authors.affiliation: Department of Emergency Medicine, Wayne State University School of Medicine, 4201 St. Antoine, 6F UHC, Detroit, MI 48201, USA.
authors.forename: Khoa
authors.initials: K
authors.lastname: Nguyen
authors.affiliation: Department of Pathology, Wayne State University School of Medicine, 540 East Canfield, Detroit, MI 48201, USA; Consolidated Laboratory Management Systems, 24555 Southfield Road, Southfield, MI 48075, USA.
authors.forename: Martin H
authors.initials: MH
authors.lastname: Bluth
authors.affiliation: Department of Emergency Medicine, Wayne State University School of Medicine, 4201 St. Antoine, 6F UHC, Detroit, MI 48201, USA. Electronic address: edube@med.wayne.edu.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Dubey
mesh_terms: D000082:Acetaminophen / Q000097:blood / Q000506:poisoning*; D018712:Analgesics, Non-Narcotic / Q000097:blood / Q000506:poisoning*; D000701:Analgesics, Opioid / Q000506:poisoning*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000506:poisoning*; D001241:Aspirin / Q000506:poisoning*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000175:diagnosis / Q000628:therapy; D004636:Emergency Service, Hospital; D006801:Humans
chemical_list: D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen; D001241:Aspirin
keywords: Acetaminophen; Aspirin; Emergency department; Narcotic; Opioid; Salicylate; Toxicity