title: Clinical Report: Schistosomiasis Exposure in U.S. Service Personnel During Whitewater Rafting on the Nile River in Jinja, Uganda.
abstract: Schistosomiasis is a known risk after exposure to freshwater in tropical parts of the world. In March 2014, 28 off-duty U.S. service members went on a water adventure in the Nile River in Jinja, Uganda. In April 2014, 10 of the 28 service members returned for a second water adventure. Twelve weeks after freshwater exposure, schistosomiasis enzyme-linked immunosorbent assay testing was performed. Twenty-five percent had elevated Schistosomiasis mansoni immunoglobulin G (7 positive of 28 exposed); all had negative pre-exposure serology. The serology-positive service members were treated with oral praziquantel 60 mg/kg in divided doses. Our report is the first schistosomiasis report among U.S. service members deployed to Africa since World War II. The absence of reports among U.S. service members and several reports among deployed foreign military units and tourists in sub-Saharan Africa suggest a lack of postexposure testing. We recommend schistosomiasis testing of prior and future U.S. military units deployed to sub-Saharan Africa with fresh water exposure. Unit commanders and medical personnel should discourage unnecessary fresh water contact in sub-Saharan Africa.
authors.affiliation: Department of Internal Medicine, Naval Medical Center, 620 John Paul Jones Circle, Portsmouth, VA 23708.
authors.forename: Samuel
authors.initials: S
authors.lastname: Maluil
authors.affiliation: Department of Surgery, CAPT James A. Lovell Federal Health Care Center, 3001 Green Bay Road, North Chicago, IL 60064.
authors.forename: Rom A
authors.initials: RA
authors.lastname: Stevens
mesh_terms: D000328:Adult; D000871:Anthelmintics / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D005618:Fresh Water / Q000382:microbiology; D006801:Humans; D008297:Male; D008889:Military Personnel / Q000706:statistics & numerical data*; D011223:Praziquantel / Q000494:pharmacology / Q000627:therapeutic use; D045483:Rivers / Q000382:microbiology*; D012552:Schistosomiasis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D012555:Schistosomiasis mansoni / Q000473:pathology; D014454:Uganda; D014481:United States / Q000453:epidemiology / Q000208:ethnology
chemical_list: D000871:Anthelmintics; D011223:Praziquantel