title: Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma.
abstract: Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe.Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area.Results. Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1,P= 0.001; IT-2,P= 0.081; and IT-3,P= 0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P= 0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV,P< 0.01, and AOD750,P< 0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all,P≤ 0.01). IC decreased at post-LPI (P< 0.001), and ACD at post-LPI did not change.Conclusions. The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, Japan.
authors.forename: Wakako
authors.initials: W
authors.lastname: Ikegawa
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, Japan.
authors.forename: Takashi
authors.identifier: 0000-0001-7396-348X
authors.initials: T
authors.lastname: Suzuki
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Namiguchi
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Mizoue
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shiraishi
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, Japan.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ohashi