title: (+)-Camphor-mediated kinetic resolution of allylalanes: a strategy towards enantio-enriched cyclohex-2-en-1-ylalane.
abstract: An efficient (+)-camphor-mediated kinetic resolution of racemic cyclohex-2-en-1-ylalane is described. This approach provides an enantiomerically enriched form of the alane, in situ available for synthetic uses. Applied to the allylation of aldehydes, this protocol leads to the corresponding homoallylalcohols in a highly enantioselective manner.
authors.affiliation: Institut de Chimie Moléculaire, CNRS (UMR 7312) and Université de Reims, 51687 Reims Cedex 2, France. jean-luc.vasse@univ-reims.fr.
authors.forename: Michaël
authors.initials: M
authors.lastname: Coffinet
authors.affiliation: Institut de Chimie Moléculaire, CNRS (UMR 7312) and Université de Reims, 51687 Reims Cedex 2, France. jean-luc.vasse@univ-reims.fr.
authors.forename: Fabien
authors.initials: F
authors.lastname: Massicot
authors.affiliation: Institut de Chimie Moléculaire, CNRS (UMR 7312) and Université de Reims, 51687 Reims Cedex 2, France. jean-luc.vasse@univ-reims.fr.
authors.forename: Jomy
authors.initials: J
authors.lastname: Joseph
authors.affiliation: Institut de Chimie Moléculaire, CNRS (UMR 7312) and Université de Reims, 51687 Reims Cedex 2, France. jean-luc.vasse@univ-reims.fr.
authors.forename: Jean-Bernard
authors.initials: JB
authors.lastname: Behr
authors.affiliation: Institut de Chimie Moléculaire, CNRS (UMR 7312) and Université de Reims, 51687 Reims Cedex 2, France. jean-luc.vasse@univ-reims.fr.
authors.forename: Florian
authors.initials: F
authors.lastname: Jaroschik
authors.affiliation: Institut de Chimie Moléculaire, CNRS (UMR 7312) and Université de Reims, 51687 Reims Cedex 2, France. jean-luc.vasse@univ-reims.fr.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Vasse
mesh_terms: D002164:Camphor / Q000737:chemistry*; D003510:Cyclohexanes / Q000737:chemistry* / Q000302:isolation & purification*; D053138:Cyclohexenes / Q000737:chemistry* / Q000302:isolation & purification*; D007700:Kinetics; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D003510:Cyclohexanes; D053138:Cyclohexenes; D009942:Organometallic Compounds; D002164:Camphor