title: Endometriosis and uterine malformations: infertility may increase severity of endometriosis.
abstract: BACKGROUND
  The aim of our study was to compare the stage and severity of endometriosis in fertile and infertile women with congenital uterine malformations.
  
  
  METHODS
  We performed an observational study from September 2007 to December 2015 in a tertiary care university hospital and assisted reproductive technology center. A total of 52 patients with surgically proven uterine malformations were included. We compared 41 infertile patients with uterine malformations with 11 fertile patients with uterine malformation. The main outcome was the stage, score and type of endometriosis in regard to infertility and class of uterine malformation.
  
  
  RESULTS
  The rate of endometriosis did not differ between the two groups (43.9 vs. 36.4%). The mean revised American Fertility Society score was higher in infertile patients with uterine malformations (19.02 vs. 6, p < 0.05). No significant difference was found in the rate of superficial peritoneal endometriosis (43.9 vs. 37.5%). Endometrioma and deep infiltrating endometriosis were associated with uterine malformations in infertile women, respectively 14.6 and 0%. No difference in the characteristics of endometriosis was found regarding the class of malformation.
  
  
  CONCLUSIONS
  The association of uterine malformations and infertility may increase the severity of endometriosis and raise the issue of their diagnosis and management.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Medecine, University Hospitals Paris Seine-Saint-Denis, Public Assistance Hospitals Paris, CHU Jean Verdier, Bondy, France.|University Paris 13, Sorbonne Paris City, UFR SMBH, Bobigny, France.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Boujenah
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Medecine, University Hospitals Paris Seine-Saint-Denis, Public Assistance Hospitals Paris, CHU Jean Verdier, Bondy, France.
authors.forename: Eleonora
authors.initials: E
authors.lastname: Salakos
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Medecine, University Hospitals Paris Seine-Saint-Denis, Public Assistance Hospitals Paris, CHU Jean Verdier, Bondy, France.
authors.forename: Mélodie
authors.initials: M
authors.lastname: Pinto
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Medecine, University Hospitals Paris Seine-Saint-Denis, Public Assistance Hospitals Paris, CHU Jean Verdier, Bondy, France.
authors.forename: Joanna
authors.initials: J
authors.lastname: Shore
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Medecine, University Hospitals Paris Seine-Saint-Denis, Public Assistance Hospitals Paris, CHU Jean Verdier, Bondy, France.|University Paris 13, Sorbonne Paris City, UFR SMBH, Bobigny, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Sifer
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Medecine, University Hospitals Paris Seine-Saint-Denis, Public Assistance Hospitals Paris, CHU Jean Verdier, Bondy, France.|University Paris 13, Sorbonne Paris City, UFR SMBH, Bobigny, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Poncelet
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Medecine, University Hospitals Paris Seine-Saint-Denis, Public Assistance Hospitals Paris, CHU Jean Verdier, Bondy, France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Bricou
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004715:Endometriosis / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology*; D012720:Severity of Illness Index; D014564:Urogenital Abnormalities / Q000150:complications* / Q000453:epidemiology
keywords: Endometriosis; infertility; severity; uterine malformation