title: Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties.
abstract: Apple juice production generates a large amount of residue comprising mainly peels, seeds, and pulp, known as apple pomace. In the global context, Brazil ranks 11th in apple production and thousands of tons of apple pomace are produced every year. This by-product is little explored, since it is a rich and heterogeneous mixture, containing interesting phytochemical groups. Among them, ursolic acid (UA) has attracted attention because of its therapeutic potential. UA is a pentacyclic triterpene found too in several traditional plants, and has shown several functional properties such as antibacterial, antiprotozoal, anti-inflammatory and antitumor. Therefore, this review attempts to shed some light on the economical viability of apple and apple pomace as sources of bioactive compounds, highlighting the UA extraction, and its main functional properties published in the last 5years (2010-2015).
authors.affiliation: Phytochemistry and Organic Synthesis Laboratory, School of Pharmacy, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Electronic address: simonetc@gmail.com.
authors.forename: Simone Tasca
authors.initials: ST
authors.lastname: Cargnin
authors.affiliation: Phytochemistry and Organic Synthesis Laboratory, School of Pharmacy, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Electronic address: simone.gnoatto@ufrgs.br.
authors.forename: Simone Baggio
authors.initials: SB
authors.lastname: Gnoatto
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis*; D027845:Malus / Q000737:chemistry*; D008519:Medicine, Traditional; D010936:Plant Extracts / Q000737:chemistry*; D014315:Triterpenes / Q000032:analysis*; D000097245:Ursolic Acid
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts; D014315:Triterpenes; D000097245:Ursolic Acid
keywords: Apple; Industrial waste; Terpenoids; Therapeutic potentials; Traditional plants