title: Preparation of Vinyl Arenes by Nickel-Catalyzed Reductive Coupling of Aryl Halides with Vinyl Bromides.
abstract: This work emphasizes the synthesis of substituted vinyl arenes by reductive coupling of aryl halides with vinyl bromides under mild and easy-to-operate nickel-catalyzed reaction conditions. A broad range of aryl halides, including heteroaromatics, and vinyl bromides were employed to yielding products in moderate to excellent yields with high functional-group tolerance. The nickel-catalytic system displays good chemoselectivity between the two C(sp2)-halide coupling partners, thus demonstrating a mechanistic pathway distinct from other stepwise protocols.
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai University of Technology, 100 Hai-Quan Road, Shanghai, 201418, China.
authors.forename: Jiandong
authors.initials: J
authors.lastname: Liu
authors.affiliation: Center for Supramolecular Materials and Catalysis and Department of Chemistry, Shanghai University, 99 Shang-Da Road, Shanghai, 200444, China.
authors.forename: Qinghua
authors.initials: Q
authors.lastname: Ren
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai University of Technology, 100 Hai-Quan Road, Shanghai, 201418, China.
authors.forename: Xinghua
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Center for Supramolecular Materials and Catalysis and Department of Chemistry, Shanghai University, 99 Shang-Da Road, Shanghai, 200444, China.
authors.forename: Hegui
authors.initials: H
authors.lastname: Gong
keywords: alkenes; arenes; cross-coupling; nickel; reaction mechanisms