title: Role of molecular imaging in the management of patients affected by inflammatory bowel disease: State-of-the-art.
abstract: OBJECTIVE
  To present the current state-of-the art of molecular imaging in the management of patients affected by inflammatory bowel disease (IBD).
  
  
  METHODS
  A systematic review of the literature was performed in order to find important original articles on the role of molecular imaging in the management of patients affected by IBD. The search was updated until February 2016 and limited to articles in English.
  
  
  RESULTS
  Fifty-five original articles were included in this review, highlighting the role of single photon emission tomography and positron emission tomography.
  
  
  CONCLUSIONS
  To date, molecular imaging represents a useful tool to detect active disease in IBD. However, the available data need to be validated in prospective multicenter studies on larger patient samples.
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Federico
authors.initials: F
authors.lastname: Caobelli
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Laura
authors.initials: L
authors.lastname: Evangelista
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Natale
authors.initials: N
authors.lastname: Quartuccio
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Demetrio
authors.initials: D
authors.lastname: Familiari
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Corinna
authors.initials: C
authors.lastname: Altini
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Angelo
authors.initials: A
authors.lastname: Castello
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Mariapaola
authors.initials: M
authors.lastname: Cucinotta
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Rossella
authors.initials: R
authors.lastname: Di Dato
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Cristina
authors.initials: C
authors.lastname: Ferrari
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Aurora
authors.initials: A
authors.lastname: Kokomani
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Iashar
authors.initials: I
authors.lastname: Laghai
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Laudicella
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Silvia
authors.initials: S
authors.lastname: Migliari
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Federica
authors.initials: F
authors.lastname: Orsini
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Salvatore Antonio
authors.initials: SA
authors.lastname: Pignata
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Cristina
authors.initials: C
authors.lastname: Popescu
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Erinda
authors.initials: E
authors.lastname: Puta
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Martina
authors.initials: M
authors.lastname: Ricci
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Silvia
authors.initials: S
authors.lastname: Seghezzi
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Sindoni
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Martina
authors.initials: M
authors.lastname: Sollini
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Letterio
authors.initials: L
authors.lastname: Sturiale
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Anna
authors.initials: A
authors.lastname: Svyridenka
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Vittoria
authors.initials: V
authors.lastname: Vergura
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.forename: Pierpaolo
authors.initials: P
authors.lastname: Alongi
authors.affiliation: Federico Caobelli, Department of Nuclear Medicine, Universitätsspital Basel, CH-4032 Basel, Switzerland.
authors.lastname: Young Aimn Working Group
keywords: 18F-Fluorodehoxiglucose positron emission tomography/computed tomography; Inflammation; Inflammatory bowel disease; Molecular imaging; White blood cell scintigraphy