title: An 8-year population description from a national treatment centre on lymphatic malformations.
abstract: BACKGROUND
  Lymphatic malformations are rare developmental non-malignant abnormalities that present as masses consisting of abnormal growth of fluid filled channels or spaces in the skin or deep tissue that result in abnormalities of lymphatic flow. They may cause symptoms like pain, recurrent lymphorrea, abnormal bone growth, and disturbance of bodily functions. They may also be a cosmetic problem. The study aims to describe the population with lymphatic malformations (LM) treated at a national referral centre.
  
  
  METHODS
  This is a retrospective review of patients with the diagnosis lymphatic malformation seen at the centre between 2006-2013. The authors performed a systematic review of the hospital records and a reevaluation of the radiological findings. Eighty-five patients with 102 lymphatic malformations were included.
  
  
  RESULTS
  The majority of the patients (67%) were diagnosed before the age of 2 years. Lesions were located mainly to the head and neck (64%) and half (52%) were macrocystic. Treatment was: sclerotherapy (69%), surgery (49%), laser therapy (19%), or a combination of these treatment modalities (33%). The best outcome was found in the patients with macrocystic lesions (p = .029), and 76% of the patients reported a good or very good outcome.
  
  
  CONCLUSIONS
  Most patients presented before the age of 2 years with complex lesions which required unique, often multimodal treatment plans and in general they experienced good outcome.
authors.affiliation: a Department of Plastic and Reconstructive Surgery , Oslo University Hospital , Oslo , Norway.
authors.forename: Jill Josefine
authors.initials: JJ
authors.lastname: Eliasson
authors.affiliation: a Department of Plastic and Reconstructive Surgery , Oslo University Hospital , Oslo , Norway.
authors.forename: Inanna
authors.initials: I
authors.lastname: Weiss
authors.affiliation: a Department of Plastic and Reconstructive Surgery , Oslo University Hospital , Oslo , Norway.|b Institute for Surgical Research , Oslo University Hospital , Oslo , Norway.
authors.forename: Hans Erik
authors.initials: HE
authors.lastname: Høgevold
authors.affiliation: a Department of Plastic and Reconstructive Surgery , Oslo University Hospital , Oslo , Norway.
authors.forename: Nina
authors.initials: N
authors.lastname: Oliver
authors.affiliation: c Department of Radiology , Oslo University Hospital , Oslo , Norway.
authors.forename: Rune
authors.initials: R
authors.lastname: Andersen
authors.affiliation: c Department of Radiology , Oslo University Hospital , Oslo , Norway.
authors.forename: Kirsti
authors.initials: K
authors.lastname: Try
authors.affiliation: a Department of Plastic and Reconstructive Surgery , Oslo University Hospital , Oslo , Norway.|b Institute for Surgical Research , Oslo University Hospital , Oslo , Norway.|d Faculty of Medicine , University of Oslo , Oslo , Norway.
authors.forename: Kim Alexander
authors.initials: KA
authors.lastname: Tønseth
mesh_terms: D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D044148:Lymphatic Abnormalities / Q000000981:diagnostic imaging / Q000628:therapy*; D008220:Lymphography / Q000379:methods; D008297:Male; D009664:Norway; D018579:Patient Selection; D012042:Registries; D012189:Retrospective Studies; D018570:Risk Assessment; D015911:Sclerotherapy / Q000379:methods*; D012720:Severity of Illness Index; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: Lymphatic malformation; cystic hygroma; liposuction; lymphangioma; macrocystic; microcystic; sclerotherapy; surgery