title: Environmentally induced tissue responses of hematopoietic system in abu mullet (Liza abu) and tiger tooth croaker (Otolithes ruber) from the Persian Gulf.
abstract: The present investigation aimed to assess the possibility of using plasma levels of erythropoietin (EPO) hormone and tissue changes of hematopoietic organs as biomarkers of environmental pollution in abu mullet (Liza abu) and tiger tooth croaker (Otolithes ruber) collected from Musa Creek (northwest of the Persian Gulf). 120 L. abu and O. ruber were collected from five stations at the Musa Creek: Petrochemical, Ghanam, Doragh, Zangi and Patil stations. Blood samples were obtained from the caudal vein. Tissue samples were also taken from the spleen and head kidney, and tissue sections were prepared according to routine histological methods. The concentrations of Hg, Pb, Zn, Cu, and Cd were also measured in the sediment samples. The minimum level of EPO and the most severe tissue changes were determined in fish collected near a Petrochemical station. This station is adjacent to the Imam Khomeini Petrochemical Complex and receives highly contaminated effluents from this complex. The highest degree of contamination (Cd) also belonged to this station. The fish collected from the Patil station represented the highest EPO level and the least tissue changes. This station exhibited a lesser degree of contamination. Based on the results, there was a significant correlation between the plasma level of EPO hormone and the degree of environmental contamination.
authors.affiliation: Department of Marine Biology, Faculty of Marine Science, Khorramshahr University of Marine Science and Technology, P.O. Box 64199-669, Khorramshahr, Iran. Electronic address: salamatnegin@yahoo.com.
authors.forename: Negin
authors.initials: N
authors.lastname: Salamat
authors.affiliation: Department of Marine Biology, Faculty of Marine Science, Khorramshahr University of Marine Science and Technology, P.O. Box 64199-669, Khorramshahr, Iran.
authors.forename: Abdolali
authors.initials: A
authors.lastname: Movahedinia
authors.affiliation: Department of Pathology, Ahwaz Jondi Shapour University of Medical Sciences, Ahwaz, Iran.
authors.forename: Parvin
authors.initials: P
authors.lastname: Kheradmand
mesh_terms: D000818:Animals; D004781:Environmental Exposure; D004784:Environmental Monitoring; D004921:Erythropoietin / Q000378:metabolism*; D029941:Fish Proteins / Q000378:metabolism*; D019015:Geologic Sediments / Q000032:analysis; D006413:Hematopoietic System / Q000187:drug effects*; D019156:Indian Ocean; D010473:Perciformes / Q000378:metabolism*; D023701:Smegmamorpha / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*
chemical_list: D029941:Fish Proteins; D014874:Water Pollutants, Chemical; D004921:Erythropoietin
keywords: Erythropoietin; Hematopoietic organs; Liza abu; Otolithes ruber; Persian Gulf