title: Zika virus: review and obstetric anesthetic clinical considerations.
abstract: OBJECTIVE
  To review the clinical and basic science literature regarding Zika viral illness and highlight relevant findings for obstetric anesthesiologists. This review provides a global review of Zika viral illness, transmission patterns, pathophysiology of disease, and anesthetic management of the parturient with Zika viral illness and associated comorbidities.
  
  
  METHODS
  Systematic review.
  
  
  METHODS
  Large academic hospital.
  
  
  METHODS
  None.
  
  
  METHODS
  None.
  
  
  METHODS
  None.
  
  
  RESULTS
  None.
  
  
  CONCLUSIONS
  With the rapid spread of Zika virus and expected increase of spread in the summer of 2016, this review provides anesthesiologists with current recommendations, physiologic alterations, and anesthetic considerations in regard to the parturient with Zika viral illness and associated diseases.
authors.affiliation: Department of Anesthesiology, Cedars-Sinai Medical Center, 8700 Beverly Blvd #8211, Los Angeles, CA 90048, USA.
authors.forename: Cesar
authors.initials: C
authors.lastname: Padilla
authors.affiliation: Department of Anesthesiology, Cedars-Sinai Medical Center, 8700 Beverly Blvd #8211, Los Angeles, CA 90048, USA.
authors.forename: Aileen
authors.initials: A
authors.lastname: Pan
authors.affiliation: Department of Anesthesiology, Cedars-Sinai Medical Center, 8700 Beverly Blvd #8211, Los Angeles, CA 90048, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Geller
authors.affiliation: Department of Anesthesiology, Cedars-Sinai Medical Center, 8700 Beverly Blvd #8211, Los Angeles, CA 90048, USA. Electronic address: Mark.Zakowski@cshs.org.
authors.forename: Mark I
authors.initials: MI
authors.lastname: Zakowski
mesh_terms: D000330:Aedes / Q000821:virology; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000818:Animals; D017848:Blood-Borne Pathogens; D005260:Female; D020275:Guillain-Barre Syndrome / Q000150:complications* / Q000453:epidemiology / Q000821:virology; D006801:Humans; D015994:Incidence; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D014481:United States / Q000453:epidemiology; D000071244:Zika Virus / Q000472:pathogenicity*; D000071243:Zika Virus Infection / Q000150:complications* / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission*
keywords: Anesthetic considerations; Guillain-Barré; Transmission prevention; Uteroplacental insufficiency; Zika virus