title: The influence of hyaluronan addition on thickness, weight, uniformity of mass and water content of mucoadhesive films.
abstract: Characteristics of the buccal mucoadhesive films (film thickness, film weight, uniformity of mass and moisture content) prepared by solvent casting method were tested in this experimental study. The formulations consisted either of one mucoadhesive polymer (sodium hyaluronate of two different molecular weights and sodium carboxymethylcellulose) or combinations thereof. On the basis of the aforementioned tests, it was determined that water content was influenced by the molecular weight of sodium hyaluronate as well as by the ratio of mucoadhesive polymers in the composition. The composition of the films influences also other tested parameters.Key words: buccal mucoadhesive films solvent casting method sodium hyaluronate sodium carboxymethylcellulose water content.
authors.forename: Veronika
authors.initials: V
authors.lastname: Walicová
authors.forename: Jan
authors.initials: J
authors.lastname: Gajdziok
authors.forename: Markéta
authors.initials: M
authors.lastname: Gajdošová
authors.forename: David
authors.initials: D
authors.lastname: Vetchý
mesh_terms: D002266:Carboxymethylcellulose Sodium / Q000032:analysis; D006820:Hyaluronic Acid / Q000737:chemistry*; D009061:Mouth Mucosa / Q000737:chemistry*; D012997:Solvents; D014867:Water / Q000032:analysis
chemical_list: D012997:Solvents; D014867:Water; D006820:Hyaluronic Acid; D002266:Carboxymethylcellulose Sodium