title: The effects of sevoflurane and desflurane on the hemodynamics and respiratory functions in laparoscopic sleeve gastrectomy.
abstract: OBJECTIVE
  Sleeve gastrectomy has been one of the most commonly performed bariatric surgery methods. The study aimed to compare the effects of 2 most commonly used inhalation anesthetics, sevoflurane and desflurane, on the peroperative hemodynamic alterations and postoperative respiratory functions in morbidly obese patients undergoing sleeve gastrectomy.
  
  
  METHODS
  Nonrandomized cohort.
  
  
  METHODS
  Operating room, postoperative period.
  
  
  METHODS
  Eighty-four morbidly obese patients with a body mass index greater than 40 kg/m2who had scheduled to undergo sleeve gastrectomy operation were prospectively included in the study.
  
  
  METHODS
  Patients were divided into 2 groups. The maintenance of inhalation anesthesia was performed by sevoflurane in 1 group (sevoflurane group) and desflurane (desflurane group) in the other group.
  
  
  METHODS
  Demographic features, peroperative hemodynamic alterations, and the results of preoperative and postoperative 24th hour respiratory function tests were recorded.
  
  
  RESULTS
  There was not any statistically significant difference between groups regarding age, sex, body mass index, anesthesia time, peroperative mean arterial pressure, arterial oxygen saturation, end-tidal carbon dioxide, and preoperative or postoperative forced expiratory volume 1/forced vital capacity ratios.
  
  
  CONCLUSIONS
  We determined that both desflurane and sevoflurane provide similar intraoperative hemodynamic and early postoperative respiratory functions in morbidly obese patients in laparoscopic sleeve gastrectomy. Both agents can be regarded as alternatives for inhalation anesthetics in maintenance of anesthesia.
authors.affiliation: Department of Anesthesiology and Reanimation, Adana Numune Training and Research Hospital, Adana, Turkey. Electronic address: hat_ka33@hotmail.com.
authors.forename: Hatice Kaya
authors.initials: HK
authors.lastname: Ozdogan
authors.affiliation: Department of General Surgery, Adana Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Cetinkunar
authors.affiliation: Department of General Surgery, Adana Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Karateke
authors.affiliation: Department of Anesthesiology and Reanimation, Adana Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Cetinalp
authors.affiliation: Department of Anesthesiology and Reanimation, Adana Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Muge
authors.initials: M
authors.lastname: Celik
authors.affiliation: Department of General Surgery, Adana Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Sefa
authors.initials: S
authors.lastname: Ozyazici
mesh_terms: D000328:Adult; D018685:Anesthetics, Inhalation / Q000494:pharmacology; D015331:Cohort Studies; D000077335:Desflurane; D005260:Female; D005743:Gastrectomy; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007530:Isoflurane / Q000031:analogs & derivatives* / Q000494:pharmacology; D010535:Laparoscopy; D008297:Male; D008738:Methyl Ethers / Q000494:pharmacology*; D009767:Obesity, Morbid / Q000601:surgery*; D011446:Prospective Studies; D012119:Respiration / Q000187:drug effects*; D012129:Respiratory Function Tests; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D000077335:Desflurane; D007530:Isoflurane
keywords: Anesthesia; Desflurane; Morbid obesity; Sevoflurane