title: Zika virus infection and biological treatment for reproductive medicine.
abstract: The recent Zika virus (ZIKV) epidemic is particularly challenging in the field of reproductive medicine as various biological tissues and byproducts, such as intravenous immunoglobulin G or cells are utilized during reproductive cycles, and an infected mother has an increased risk of having babies with fetal microcephaly and other congenital brain anomalies. In this review, current guidelines for prevention of sexual transmission of ZIKV, ZIKV testing, and tissue and blood product usages are summarized for physicians caring for those planning pregnancy or going through infertility treatment.
authors.affiliation: Reproductive Medicine, Department of Obstetrics and Gynecology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA.|Department of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
authors.forename: Joanne
authors.initials: J
authors.lastname: Kwak-Kim
authors.affiliation: Reproductive Medicine, Department of Obstetrics and Gynecology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA.
authors.forename: Jeehey
authors.initials: J
authors.lastname: Song
authors.affiliation: Reproductive Medicine, Department of Obstetrics and Gynecology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA.
authors.forename: Michael Woo-Il
authors.initials: MW
authors.lastname: Kim
authors.affiliation: Department of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
authors.forename: Alice
authors.initials: A
authors.lastname: Gilman-Sachs
mesh_terms: D000818:Animals; D001691:Biological Therapy; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology*; D018445:Infectious Disease Transmission, Vertical; D008403:Mass Screening; D008831:Microcephaly / Q000453:epidemiology*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D018456:Reproductive Medicine; D000071244:Zika Virus / Q000502:physiology*; D000071243:Zika Virus Infection / Q000453:epidemiology / Q000628:therapy*
chemical_list: D016756:Immunoglobulins, Intravenous
keywords: 
  IVIG
  ; Zika; guidelines; immunotherapy; infertility; pregnancy