title: A case of alopecia as IgG4-related skin disease.
abstract: A 53-year-old man with autoimmune pancreatitis as IgG4-related disease presented alopecia. Immunostaining showed perifollicular infiltration of IgG4-positive cells and perifollicular/intrafollicular infiltration of predominantly CD4-positive cells, especially in the upper and lower parts. Alopecia areata is characterized by perifollicular/intrafollicular lymphocyte infiltration of the lower bulb and inflammation in the upper dermis. We determined the patient had IgG4-related skin disease, rather than alopecia areata. Alopecia as IgG4-related skin disease has not been reported previously.
authors.affiliation: a Department of Dermatology , Wakayama Medical University, Graduate School of Medicine , Wakayama , Japan.
authors.forename: Takaharu
authors.initials: T
authors.lastname: Ikeda
authors.affiliation: a Department of Dermatology , Wakayama Medical University, Graduate School of Medicine , Wakayama , Japan.
authors.forename: Chikako
authors.initials: C
authors.lastname: Kaminaka
authors.affiliation: a Department of Dermatology , Wakayama Medical University, Graduate School of Medicine , Wakayama , Japan.
authors.forename: Fukumi
authors.initials: F
authors.lastname: Furukawa
mesh_terms: D000506:Alopecia Areata / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D006801:Humans; D000077733:Immunoglobulin G4-Related Disease / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged
keywords: Alopecia; IgG4-related disease; IgG4-related skin disease