title: Preliminary experience with high-density electroanatomical mapping for ablation of atrial fibrillation - Comparison of mini-basket and novel open irrigated magnetic ablation catheter in consecutive patients.
abstract: BACKGROUND
  Recently, a novel electroanatomic mapping system enabling rapid and automatic acquisition of high-resolution maps has been introduced. Previous reports focused on system use in combination with a mini-basket catheter. However, a novel system-specific, magnet-enabled ablation catheter eliminates the need for the mini-basket catheter and can potentially reduce procedure complexity and cost. Here we present our first experience from two consecutive case series using both procedural settings.
  
  
  METHODS
  In 14 consecutive patients (67±9years, 5 male) with paroxysmal (n=10) or persistent AF (n=4) undergoing de-novo (n=8) or repeat (n=6) AF ablation, left atrial electroanatomical maps were acquired with a mini-basket and in 22 patients (64±9years, 17 male) with paroxysmal (n=4) or persistent AF (n=18) undergoing de-novo (n=12) or repeat (n=10) AF ablation with the new ablation catheter.
  
  
  RESULTS
  Both complete (7.9 [IQR 4.5-16.2] vs 18.8 [IQR 12.0-25.5] minutes, p=0.005) and partial maps (3.0 [IQR 2.0-4.6] vs 4.5 [IQR 2.0-6.0] minutes, p=0.014) acquired with mini-basket required significantly shorter mapping time and had higher point density: 8832±4809 vs 4460±3914 (p=0.014) and 2483±1774 vs 1111±1926 data points (p=0.002) in partial maps. However, procedural (201±52 vs 159±29min, p=0.004) and fluoroscopy time (33±11 vs 25±6min, p=0.005) was significantly higher in the mini-basket group. Procedural endpoints and complications rates were similar in both groups.
  
  
  CONCLUSIONS
  The high-density mapping system can successfully be used with both mini-basket catheters and ablation catheters employed for electro-anatomic reconstruction of the left atrium. While mapping is faster and point density higher with the mini-basket, procedure and fluoroscopy times are longer. The clinical significance of those findings needs to be investigated in future and larger studies.
authors.affiliation: Department of Electrophysiology, Heart Center, Leipzig, Leipzig, Germany. Electronic address: jedrzejkosiuk@hotmail.com.
authors.forename: Jedrzej
authors.initials: J
authors.lastname: Kosiuk
authors.affiliation: Department of Electrophysiology, Heart Center, Leipzig, Leipzig, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Hilbert
authors.affiliation: Department of Electrophysiology, Heart Center, Leipzig, Leipzig, Germany.
authors.forename: Silke
authors.initials: S
authors.lastname: John
authors.affiliation: Department of Electrophysiology, Heart Center, Leipzig, Leipzig, Germany.
authors.forename: Livio
authors.initials: L
authors.lastname: Bertagnolli
authors.affiliation: Department of Electrophysiology, Heart Center, Leipzig, Leipzig, Germany.
authors.forename: Gerhard
authors.initials: G
authors.lastname: Hindricks
authors.affiliation: Department of Electrophysiology, Heart Center, Leipzig, Leipzig, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Bollmann
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D018780:Body Surface Potential Mapping / Q000379:methods*; D017115:Catheter Ablation / Q000295:instrumentation*; D057785:Catheters; D004867:Equipment Design; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008280:Magnetics / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
keywords: Atrial fibrillation; Cardiac mapping; Catheter ablation; Rhythmia