title: [The effects of cycloplegic eyedrops on corneal tomography].
abstract: OBJECTIVE
  Whether cycloplegics affect standard keratorefractometric and tomographic measurements is unknown. The purpose of our study was to compare the effects of cycloplegics (cyclopentolate and atropine) on corneal shape and refractive power of the eye.
  
  
  METHODS
  This study was performed on 84 eyes of 49 study participants. Patients were randomized into two groups: atropine 1% (32 eyes) and cyclopentolate 1% (52 eyes). Corneal tomography was performed with the Orbscan IIz. To evaluate the corneal shape, simulated keratometry values, anterior and posterior best-fit sphere, white-to-white and tangential and axial corneal power were performed for the anterior and posterior corneal surfaces before and during cycloplegia. Pupil diameter, anterior chamber depth, corneal thickness at the 3, 5 and 7mm optical zones, thinnest area of the cornea and corneal thickness at the visual axis were examined. Data were analyzed using an SPSS statistical package.
  
  
  RESULTS
  The anterior and posterior BFS (in the atropine 1% group, anterior BFS was P=0.188; anterior BFS in the cyclopentolate group was P=0.227) and tangential and axial corneal power showed no change during cycloplegia in either group. SimK showed no statistical significance. The ACD was deeper when using atropine than cyclopentolate. Corneal thickness remained unchanged during cycloplegia in both groups. Pupil diameter was larger in light-colored irides in the cyclopentolate group than the atropine group. There was no change in W to W before (P=0.473) and during cycloplegia (P=0.287) in either group.
  
  
  CONCLUSIONS
  Our results suggest that usage of atropine or cyclopentolate does not alter corneal shape.
authors.affiliation: Département de cornée et des maladies externes, clinique des maladies des yeux, centre clinique de Serbie, faculté de médecine, université de Belgrade, 2, rue Pasterova, 11000 Belgrade, Serbie. Electronic address: tanjakalezic@gmail.com.
authors.forename: T
authors.initials: T
authors.lastname: Kalezic
authors.affiliation: Clinique de gynécologie et d'obstétrique, centre clinique de Serbie, faculté de médecine, université de Belgrade, Belgrade, Serbie.
authors.forename: I
authors.initials: I
authors.lastname: Vukovic
authors.affiliation: Département de prosthodontie, faculté de médecine dentaire, université de Belgrade, Belgrade, Serbie.
authors.forename: M
authors.initials: M
authors.lastname: Andjelkovic
authors.affiliation: Institut de statistique médicale, faculté de médecine, université de Belgrade, Belgrade, Serbie.
authors.forename: M
authors.initials: M
authors.lastname: Gajic
authors.affiliation: Département de cornée et des maladies externes, clinique des maladies des yeux, centre clinique de Serbie, faculté de médecine, université de Belgrade, 2, rue Pasterova, 11000 Belgrade, Serbie.
authors.forename: J
authors.initials: J
authors.lastname: Potic
authors.affiliation: Département de cornée et des maladies externes, clinique des maladies des yeux, centre clinique de Serbie, faculté de médecine, université de Belgrade, 2, rue Pasterova, 11000 Belgrade, Serbie.
authors.forename: M
authors.initials: M
authors.lastname: Stojkovic
mesh_terms: D000328:Adult; D001285:Atropine / Q000008:administration & dosage / Q000494:pharmacology*; D003315:Cornea / Q000187:drug effects* / Q000473:pathology / Q000601:surgery; D019781:Corneal Topography; D003519:Cyclopentolate / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009184:Mydriatics / Q000008:administration & dosage / Q000494:pharmacology*; D009883:Ophthalmic Solutions / Q000494:pharmacology*; D012029:Refraction, Ocular / Q000187:drug effects; D054140:Refractive Surgical Procedures
chemical_list: D009184:Mydriatics; D009883:Ophthalmic Solutions; D001285:Atropine; D003519:Cyclopentolate
keywords: Chirurgie réfractive; Corneal shape; Corneal tomography; Cycloplegics; Cycloplégie; Forme cornéenne; Refractive surgery; Tomographie cornéenne