title: Salmonella colitis as an unusual cause of elevated serum lipase.
abstract: Authors and clinicians advocate lipase as the preferred serological test for the diagnosis for acute pancreatitis. While acute pancreatitis is among the differential diagnosis for elevated lipase levels, several other causes of elevated lipase levels have been identified including several reports Salmonella species as a causative agent. There also have been retrospective studies that have reported clinical pancreatitis associated with Salmonella infection. These studies concluded that clinical pancreatitis should be considered as a complication of Salmonella infections. However, Salmonella infections may induce elevated pancreatic enzyme levels without clinical pancreatitis or morphological pancreatic abnormalities through a variety of proposed mechanisms. The following is a case that describes a patient who developed Salmonella colitis and demonstrated elevated serum lipase levels without clinical pancreatitis.
authors.affiliation: Department of Medicine, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, United States. Electronic address: deanr@upstate.edu.
authors.forename: Ryan
authors.initials: R
authors.lastname: Dean
authors.affiliation: Department of Medicine, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, United States.
authors.forename: Dalvir
authors.initials: D
authors.lastname: Gill
authors.affiliation: Department of Medicine, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, United States.
authors.forename: Debra
authors.initials: D
authors.lastname: Buchan
mesh_terms: D015746:Abdominal Pain / Q000097:blood / Q000000981:diagnostic imaging / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D003092:Colitis / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000097:blood / Q000000981:diagnostic imaging / Q000382:microbiology; D006801:Humans; D008049:Lipase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009325:Nausea; D010195:Pancreatitis; D011860:Radiography, Abdominal; D012480:Salmonella Infections / Q000097:blood* / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014839:Vomiting
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D008049:Lipase
keywords: Lipase; Pancreatic lipase, human; Salmonella