title: Vancomycin-resistant Enterococcus bacteremia in a child with acute myeloid leukemia: successful treatment with daptomycin.
abstract: Multiple-drug-resistant enterococcal infections canbe a serious problem in pediatric patients particularly concomitance with severe underlying diseases and lead to significant morbidity and mortality. The treatment options in children are limited compared with adults. We report a 3-year old-boy with acute myeloid leukemia (AML)-M7 and vancomycin-resistant enterococcus bacteremia successfully treated with daptomycin. Daptomycin may be an alternative therapy for VRE infections in children; more studies are needed for extended usage.
authors.affiliation: Pediatric Infectious Diseases Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. dr.aysebaktir@gmail.com.
authors.forename: Ayşe
authors.initials: A
authors.lastname: Büyükcam
authors.affiliation: Pediatric Infectious Diseases Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Eda
authors.initials: E
authors.lastname: Karadağ Öncel
authors.affiliation: Pediatric Infectious Diseases Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Özsürekçi
authors.affiliation: Pediatric Infectious Diseases Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Ali B
authors.initials: AB
authors.lastname: Cengiz
authors.affiliation: Bone Marrow Transplantation Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Barış
authors.initials: B
authors.lastname: Kuşkonmaz
authors.affiliation: Department of Medical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Banu
authors.initials: B
authors.lastname: Sancak
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology*; D002675:Child, Preschool; D017576:Daptomycin / Q000627:therapeutic use*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D012074:Remission Induction; D065507:Vancomycin-Resistant Enterococci
chemical_list: D000900:Anti-Bacterial Agents; D017576:Daptomycin
keywords: Child; Daptomycin; Linezolid; Vancomycin resistant Enterococci