title: Blood Pressure Control in Smokers with Arterial Hypertension Who Switched to Electronic Cigarettes.
abstract: Electronic cigarettes (ECs) are battery-operated devices designed to vaporise nicotine, which may help smokers with quitting or reducing their tobacco consumption. No data is available regarding the health effects of ECs use among smokers with arterial hypertension and whether regular use results in blood pressure (BP) changes. We investigated long-term changes in resting BP and level of BP control in hypertensive smokers who quit or reduced substantially their tobacco consumption by switching to ECs. A medical records review of patients with hypertension was conducted to identify patients reporting regular daily use of ECs on at least two consecutive follow-up visits. Regularly smoking hypertensive patients were included as a reference group. A marked reduction in cigarette consumption was observed in ECs users (n= 43) though consumption remained unchanged in the control group (n= 46). Compared to baseline, at 12 months (follow-up visit 2) decline in cigarette consumption was associated with significant reductions in median (25th-, 75th-centile) systolic BP (140 (134.5, 144) to 130 (123.5, 138.5) mmHg;p< 0.001) and diastolic BP (86 (78, 90) to 80 (74.5, 90) mmHg;p= 0.006). No significant changes were observed in the control group. As expected, decline in cigarette consumption in the ECs users was also associated with improved BP control. The study concludes that regular ECs use may aid smokers with arterial hypertension reduce or abstain from cigarette smoking, with only trivial post-cessation weight gain. This resulted in improvements in systolic and diastolic BP as well as better BP control.
authors.affiliation: UOC di Medicina Interna e d'Urgenza Edificio 4, Piano 3, AOU "Policlinico-V. Emanuele", University of Catania, Via S. Sofia 78, 95123 Catania, Italy. polosa@unict.it.|Centro per la Prevenzione e Cura del Tabagismo (CPCT), "Policlinico-V. Emanuele", University of Catania, 95123 Catania, Italy. polosa@unict.it.|Internal and Emergency Medicine, "Policlinico-V. Emanuele", University of Catania, 95123 Catania, Italy. polosa@unict.it.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Polosa
authors.affiliation: Department of Respiratory Medicine, Royal Brompton & Harefield Hospital NHS Trust, Harefield Hospital, Hill End Road, Harefield UB9 6JH, UK. jbmorjaria@gmail.com.
authors.forename: Jaymin B
authors.initials: JB
authors.lastname: Morjaria
authors.affiliation: UOC di Medicina Interna e d'Urgenza Edificio 4, Piano 3, AOU "Policlinico-V. Emanuele", University of Catania, Via S. Sofia 78, 95123 Catania, Italy. p.caponnetto@unict.it.|Centro per la Prevenzione e Cura del Tabagismo (CPCT), "Policlinico-V. Emanuele", University of Catania, 95123 Catania, Italy. p.caponnetto@unict.it.
authors.forename: Pasquale
authors.initials: P
authors.lastname: Caponnetto
authors.affiliation: UOC di Medicina Interna e d'Urgenza Edificio 4, Piano 3, AOU "Policlinico-V. Emanuele", University of Catania, Via S. Sofia 78, 95123 Catania, Italy. eliana.battaglia@hotmail.it.|Internal and Emergency Medicine, "Policlinico-V. Emanuele", University of Catania, 95123 Catania, Italy. eliana.battaglia@hotmail.it.
authors.forename: Eliana
authors.initials: E
authors.lastname: Battaglia
authors.affiliation: MCAU ARNAS Garibaldi, 95100 Catania, Italy. kristina_russo@yahoo.com.
authors.forename: Cristina
authors.initials: C
authors.lastname: Russo
authors.affiliation: MCAU ARNAS Garibaldi, 95100 Catania, Italy. claudiociampi@yahoo.it.
authors.forename: Claudio
authors.initials: C
authors.lastname: Ciampi
authors.affiliation: Rex Hospital, UNC Health System, Raleigh, NC 27607, USA. george.adams@unchealth.unc.edu.
authors.forename: George
authors.initials: G
authors.lastname: Adams
authors.affiliation: UOC di Medicina Interna e d'Urgenza Edificio 4, Piano 3, AOU "Policlinico-V. Emanuele", University of Catania, Via S. Sofia 78, 95123 Catania, Italy. cmbruno@unict.it.|Internal and Emergency Medicine, "Policlinico-V. Emanuele", University of Catania, 95123 Catania, Italy. cmbruno@unict.it.
authors.forename: Cosimo M
authors.initials: CM
authors.lastname: Bruno
mesh_terms: D001794:Blood Pressure; D066300:Electronic Nicotine Delivery Systems / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D012907:Smoking
keywords: blood pressure; electronic cigarette; hypertension; smoking cessation; tobacco harm reduction