title: High Frequency of OXA-253-Producing Acinetobacter baumannii in Different Hospitals in Recife, Brazil.
abstract: Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with blaOXA-253In all strains, the blaOXA-253gene was located in a plasmid within a genetic environment similar to what was found previously in Brazil and Italy. The reported data emphasize the successful transmission of the blaOXA-253gene through a large area and the tendency for this resistance determinant to remain in the A. baumannii population.
authors.affiliation: Laboratório de Resistência Microbiana, Instituto de Ciências Biológicas, Universidade de Pernambuco, Recife, Brazil.|Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
authors.forename: Felipe Lira
authors.initials: FL
authors.lastname: de Sá Cavalcanti
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
authors.forename: Carina Lucena
authors.initials: CL
authors.lastname: Mendes-Marques
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.|Departamento de Genética, Universidade Federal de Pernambuco, Recife, Brazil.
authors.forename: Crhisllane Rafaele Dos Santos
authors.initials: CR
authors.lastname: Vasconcelos
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
authors.forename: Túlio
authors.initials: T
authors.lastname: de Lima Campos
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
authors.forename: Antonio Mauro
authors.initials: AM
authors.lastname: Rezende
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
authors.forename: Danilo Elias
authors.initials: DE
authors.lastname: Xavier
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
authors.forename: Nilma Cintra
authors.initials: NC
authors.lastname: Leal
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil.
authors.forename: Osvaldo Pompilio
authors.initials: OP
authors.lastname: de-Melo-Neto
authors.affiliation: Laboratório de Resistência Microbiana, Instituto de Ciências Biológicas, Universidade de Pernambuco, Recife, Brazil.
authors.forename: Marcia Maria Camargo
authors.initials: MM
authors.lastname: de Morais
authors.affiliation: Centro de Pesquisas Aggeu Magalhães/Fiocruz, Recife, Pernambuco, Brazil cristina@cpqam.fiocruz.br.
authors.forename: Tereza Cristina
authors.initials: TC
authors.lastname: Leal-Balbino
mesh_terms: D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D006761:Hospitals; D007558:Italy; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C108449:oxacillinase
keywords: Acinetobacter; MLST; antibiotic resistance; genome analysis; oxacillinase