title: The adenoma miss rate of blue-laser imaging vs. white-light imaging during colonoscopy: a randomized tandem trial.
abstract: Background and study aimsThe aim of the present study was to determine whether blue-laser imaging (BLI) reduced the miss rate of colon adenomatous lesions compared with conventional white-light imaging (WLI).Patients and methodsThis was a prospective randomized study of patients undergoing screening and/or surveillance colonoscopy at Saga Medical School, Japan. A total of 127 patients were randomized to tandem colonoscopy with BLI followed by WLI (BLI-WLI group) or WLI followed by WLI (WLI-WLI group). The main outcome measure was the adenoma miss rate.ResultsThe proportion of patients with adenomatous lesions was 62.5 % (40 /64) in the BLI-WLI group and 63.5 % (40 /63) in the WLI-WLI group. The total number of adenomatous lesions detected in the first inspection of the BLI-WLI and WLI-WLI groups was 179 and 108, respectively, compared with 182 and 120 in the second inspection, respectively. The miss rate in the BLI-WLI group was (1.6 %), which was significantly less than that in the WLI-WLI group (10.0 %,P= 0.001).ConclusionsColonoscopy using BLI resulted in a lower colon adenoma miss rate than WLI.Trial registration UMIN 000015677.
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Shimoda
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Sakata
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Fujise
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Kohei
authors.initials: K
authors.lastname: Yamanouchi
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Nanae
authors.initials: N
authors.lastname: Tsuruoka
authors.affiliation: Department of Preventive Medicine, Saga Medical School, Japan.
authors.forename: Megumi
authors.initials: M
authors.lastname: Hara
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakayama
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yamaguchi
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Akutagawa
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Fujimoto
authors.affiliation: Department of Internal Medicine and Gastrointestinal Endoscopy, Saga Medical School, Japan.
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Iwakiri
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000473:pathology; D000368:Aged; D003111:Colonic Polyps / Q000175:diagnosis / Q000473:pathology; D003113:Colonoscopy / Q000295:instrumentation* / Q000379:methods; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000473:pathology; D003951:Diagnostic Errors / Q000517:prevention & control; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods; D007834:Lasers; D008027:Light; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome