title: BTLA+Dendritic Cells: The Regulatory T Cell Force Awakens.
abstract: The role of dendritic cells (DCs) in the induction of antigen-specific tolerance mediated by extrathymic regulatory T (Treg) cells remains incompletely defined. In this issue of Immunity, Jones et al. (2016) show that BTLA+DEC205+CD8+CD11c+DCs efficiently induce peripheral Treg cells via the engagement of HVEM, a receptor for BTLA.
authors.affiliation: Department of Surgery, University of Maryland School of Medicine, 29 South Greene Street, Baltimore, MD 21201, USA; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, 800 West Baltimore Street, Baltimore, MD 21201, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Simon
authors.affiliation: Department of Surgery, University of Maryland School of Medicine, 29 South Greene Street, Baltimore, MD 21201, USA; Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, 800 West Baltimore Street, Baltimore, MD 21201, USA; Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA; Marlene and Stewart Greenebaum Cancer Center, 22 South Greene Street, Baltimore, MD 21201, USA. Electronic address: jbromberg@smail.umaryland.edu.
authors.forename: Jonathan S
authors.initials: JS
authors.lastname: Bromberg
mesh_terms: D000941:Antigens; D003713:Dendritic Cells / Q000276:immunology; D007108:Immune Tolerance / Q000276:immunology; D011971:Receptors, Immunologic / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
chemical_list: D000941:Antigens; D011971:Receptors, Immunologic