title: Mitochondrial fusion: Reaching the end of mitofusin's tether.
abstract: In this issue, Qi et al. (2016. J. Cell Biol https://doi.org/10.1083/jcb.201609019) provide structural insights into the mechanisms of mitochondrial outer membrane fusion by investigating the structure of mitofusin 1 (MFN1). This work proposes a new model to explain the important and elusive process of MFN-mediated mitochondrial fusion.
authors.affiliation: Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Victoria 3800, Australia.
authors.forename: Luke E
authors.initials: LE
authors.lastname: Formosa
authors.affiliation: Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Victoria 3800, Australia michael.ryan@monash.edu.au.
authors.forename: Michael T
authors.initials: MT
authors.lastname: Ryan
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000378:metabolism; D063154:Mitochondrial Dynamics; D033681:Mitochondrial Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D009154:Mutation / Q000235:genetics
chemical_list: D033681:Mitochondrial Membrane Transport Proteins