title: Phaeochromocytoma and Paraganglioma.
abstract: Phaeochromocytomas and paragangliomas are relatively uncommon tumours which may be manifest in many ways, specifically as sustained or paroxysmal hypertension, episodes of palpitations, sweating, headache and anxiety, or increasingly as an incidental finding. Recent studies have shown that an increasing number are due to germline mutations. This review concentrates on the diagnosis, biochemistry and treatment of these fascinating tumours.
authors.affiliation: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.|Ministry of Health, Colombo, Sri Lanka.
authors.forename: P T Kavinga
authors.initials: PTK
authors.lastname: Gunawardane
authors.affiliation: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. endo@thelondonclinic.co.uk.
authors.forename: Ashley
authors.initials: A
authors.lastname: Grossman
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D001794:Blood Pressure; D002395:Catecholamines / Q000378:metabolism; D020022:Genetic Predisposition to Disease; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology; D010235:Paraganglioma / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D010641:Phenotype; D010673:Pheochromocytoma / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D002395:Catecholamines
keywords: Diagnosis; Malignant; Paragangliomas; Phaeochromocytomas; Review; Treatment