title: α-Ketoglutarate dehydrogenase complex moonlighting: ROS signalling added to the list: An Editorial highlight for 'Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?'
abstract: Read the highlighted article 'Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?' on page 823.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Salamanca, Salamanca, Spain.|Institute of Functional Biology and Genomics (IBFG), CSIC-University of Salamanca, Salamanca, Spain.
authors.forename: Emilio
authors.initials: E
authors.lastname: Fernandez
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Salamanca, Salamanca, Spain.|Institute of Functional Biology and Genomics (IBFG), CSIC-University of Salamanca, Salamanca, Spain.
authors.forename: Juan P
authors.initials: JP
authors.lastname: Bolaños
mesh_terms: D000818:Animals; D006801:Humans; D007655:Ketoglutarate Dehydrogenase Complex / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008928:Mitochondria / Q000201:enzymology*; D019636:Neurodegenerative Diseases / Q000201:enzymology* / Q000628:therapy; D017382:Reactive Oxygen Species / Q000378:metabolism*
chemical_list: D017382:Reactive Oxygen Species; D007655:Ketoglutarate Dehydrogenase Complex