title: Clinicomorphological Spectrum of Ovarian Cystic Lesions.
abstract: Background Ovarian cysts, which present as neoplastic and non-neoplastic lesions, are the most common gynaecological cause of hospital admissions. Early diagnosis is difficult due to asymptomatic nature. Clinical, radiological and gross examination alone cannot distinguish benign from malignant lesions, hence, histopathological examination is important for diagnostic, therapeutic and prognostic approach. Objective The objective of the study is to analyze the spectrum of ovarian cystic lesions with their clinico-morphorgical features. Method This is a prospective study done in between July 2014 and July 2015 in Dhulikhel Hospital-Kathmandu University Hospital. Clinical data of patients were obtained from hospital records and requisition submitted along with the tissue specimens received in the department. Result A total 84 cases of ovarian cystic lesions were studied. Among these, 47 (55.9%) were non-neoplastic lesions, 33 (39.3%) were benign neoplasms, two (2.4%) were borderline and two (2.4%) were malignant neoplasms. The most common nonneoplastic lesions were follicular cysts, 26 (55.3%) followed by simple cysts 14 (29.8%), hemorrhagic cysts five (10.6%) and corpus luteal cysts two (4.3%). Among all neoplasms, 19 (51.4%) were mature cystic teratoma followed by 10 (27.0%) cases of mucinous cystadenoma and four (10.8%) cases of serous cystadenoma. Between two (5.4%) malignant cases, one was immature cystic teratoma and the other was mucinous cystadenocarcinoma. Besides these, two (5.4%) cases of borderline mucinous cystadenoma were also present. Conclusion Ovarian cystic lesions are difficult to categorize on the basis of clinical and radiological findings. Histopathological examination plays a significant role to differentiate benign lesion from malignant as well as for the proper management.
authors.affiliation: Department of Pathology, Kathmandu University School of Medical Sciences Dhulikhel, Kavre, Nepal.
authors.forename: R
authors.initials: R
authors.lastname: Dhakal
authors.affiliation: Department of Pathology, Kathmandu University School of Medical Sciences Dhulikhel, Kavre, Nepal.
authors.forename: R
authors.initials: R
authors.lastname: Makaju
authors.affiliation: Department of Gynecology and Obstetrics Kathmandu University School of Medical Sciences Dhulikhel, Kavre, Nepal.
authors.forename: R
authors.initials: R
authors.lastname: Bastakoti
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008875:Middle Aged; D010048:Ovarian Cysts / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology; D011446:Prospective Studies; D055815:Young Adult