title: Comparative evaluation of the efficacy of fluoride varnish and casein phosphopeptide - Amorphous calcium phosphate in reducingStreptococcus mutanscounts in dental plaque of children: Anin vivostudy.
abstract: OBJECTIVE
  To assess the comparative efficacy of fluoride varnish and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) complex visa viz.Streptococcus mutansin plaque, and thereby the role that these two agents could play in the prevention of dental caries.
  
  
  METHODS
  A cluster sample of 120 caries inactive individuals belonging to moderate and high caries risk group were selected from 3-5-year-old age group based on the criteria given by Krassee and were randomized to four groups, namely, fluoride varnish - Group I, CPP-ACP complex - Group II, mixture of CPP-ACP complex -Gourp III, and fluoride and routine oral hygiene procedures as control - Group IV. The results thus obtained were analyzed using Statistical Package for the Social Sciences (SPSS) version 16.
  
  
  RESULTS
  A statistically significant difference in the pre and post-application scores ofS. mutans(P< 0.01) count was observed in all the groups with CPP-ACP plus fluoride group being the most proficient.
  
  
  CONCLUSIONS
  Materials such as fluoride varnish, CPP-ACP, and CPP-ACP plus fluoride protects the tooth structure, preserving the integrity of primary dentition, with the most encouraging results being with CPP-ACP plus fluoride.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur, Maharashtra, India.
authors.forename: Shweta
authors.initials: S
authors.lastname: Chandak
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur, Maharashtra, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Bhondey
authors.affiliation: Department of Orthodontics, Modern Dental College and Research Centre, Thane, Maharashtra, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Bhardwaj
authors.affiliation: Consultant Pediatric Dentist, Thane, Maharashtra, India.
authors.forename: Jitesh
authors.initials: J
authors.lastname: Pimpale
authors.affiliation: Consultant Pediatric Dentist, Kalyan, Maharashtra, India.
authors.forename: Manisha
authors.initials: M
authors.lastname: Chandwani
keywords: Casein phosphopeptide–amorphous calcium phosphate (CPP–ACP); Streptococcus mutans; fluoride varnish