title: Influence of Selenium on the Production of T-2 Toxin by Fusarium poae.
abstract: The objective of this study was to investigate the effects of selenium on the production of T-2 toxin by a Fusarium poae strain cultured in a synthetic medium containing different concentrations of selenium. The T-2 toxin contents in fermentative products were evaluated by a high performance liquid chromatography (HPLC). The results showed that the production of T-2 toxin was correlated with the concentration of selenium added to the medium. In all three treatments, the addition of 1 mg/L selenium to the medium resulted in a lower toxin yield than the control (0 mg/L); the yield of the toxin began to increase when selenium concentration was 10 mg/L, while it decreased again at 20 mg/L. In summary, T-2 toxin yield in the fermentative product was affected by the addition of selenium to the medium, and a selenium concentration of 20 mg/L produced the maximum inhibitory effect of T-2 toxin yield in the fermentative product of F. poae.
authors.affiliation: College of Life Science, Northwest University, Xi'an, 710069, China.
authors.forename: Bolun
authors.initials: B
authors.lastname: Cheng
authors.affiliation: College of Life Science, Northwest University, Xi'an, 710069, China.|Baoji Center for Disease Control and Prevention, Baoji, 721006, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Life Science, Northwest University, Xi'an, 710069, China.
authors.forename: Bei
authors.initials: B
authors.lastname: Tong
authors.affiliation: College of Life Science, Northwest University, Xi'an, 710069, China. hyin2006@163.com.|Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, 710069, China. hyin2006@163.com.
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
mesh_terms: D004305:Dose-Response Relationship, Drug; D005670:Fusarium / Q000378:metabolism*; D012643:Selenium / Q000494:pharmacology*; D013605:T-2 Toxin / Q000096:biosynthesis*
chemical_list: D012643:Selenium; D013605:T-2 Toxin
keywords: Fusarium poae; Kashin-Beck disease; Selenium; T-2 toxin