title: Scorpion venoms in gastric cancer.
abstract: Venom secretions from snakes, scorpions, spiders and bees, have been widely applied in traditional medicine and current biopharmaceutical research. Possession of anticancer potential is another novel discovery for animal venoms and toxins. An increasing number of studies have shown the anticancer effects of venoms and toxins of snakes, and scorpionsin vitroandin vivo, which were achieved mainly through the inhibition of cancer growth, arrest of cell cycle, induction of apoptosis and suppression of cancer metastasis. However, more evidence is needed to support this concept and the mechanisms of anticancer actions are not clearly understood. The present review is focused on the recant updates on anticancer venom research.
authors.affiliation: Nanjing University of Chinese Medicine, Information Institute, Nanjing, Jiangsu 221009, P.R. China.
authors.forename: Xiao-Ying
authors.initials: XY
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Xuzhou Central Hospital, The Affiliated Xuzhou Hospital of Medical College of Southeast University, Xuzhou, Jiangsu 221009, P.R. China.
authors.forename: Pei-Ying
authors.initials: PY
authors.lastname: Zhang
keywords: cancer; therapeutics; venom