title: Bio-medically active zinc oxide nanoparticles synthesized by using extremophilic actinobacterium, Streptomyces sp. (MA30) and its characterization.
abstract: The present study describes the synthesis of zinc oxide nanoparticles (ZnO-NPs) using an extremophilic actinobacterial cell-free extract, supplied with aqueous zinc acetate solution. Crystalline nature, morphological features, and polydispersed nanoparticles size (15-30 nm) were identified by X-ray diffraction (XRD), atomic force and electron microscopic analysis with dynamic light scattering (DLS) study. The interaction between biomolecules and ZnO-NPs was analyzed using Fourier transform infra-red spectroscopy (FT-IR). Furthermore antibacterial, antioxidant activities, and cell viability test of ZnO-NPs were systematically evaluated. The present study opens a new avenue for the actinobacterial synthesis of oxide nanoparticles.
authors.affiliation: a Actinobacterial Research Laboratory, Department of Microbiology , School of Biosciences, Periyar University , Salem , India.
authors.forename: Thangavel
authors.initials: T
authors.lastname: Shanmugasundaram
authors.affiliation: a Actinobacterial Research Laboratory, Department of Microbiology , School of Biosciences, Periyar University , Salem , India.
authors.forename: Ramasamy
authors.initials: R
authors.lastname: Balagurunathan
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000378:metabolism* / Q000494:pharmacology / Q000633:toxicity; D045744:Cell Line, Tumor; D060326:Chemistry Techniques, Synthetic; D002522:Chlorocebus aethiops; D006801:Humans; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology; D010316:Particle Size; D013302:Streptomyces / Q000378:metabolism*; D014709:Vero Cells; D014867:Water / Q000737:chemistry; D019345:Zinc Acetate / Q000737:chemistry; D015034:Zinc Oxide / Q000737:chemistry* / Q000378:metabolism* / Q000494:pharmacology / Q000633:toxicity
chemical_list: D000900:Anti-Bacterial Agents; D014867:Water; D019345:Zinc Acetate; D015034:Zinc Oxide
keywords: Biosynthesis; Streptomyces sp; antibacterial; antioxidant; zinc oxide