title: Zika and pregnancy: A comprehensive review.
abstract: Zika virus (ZIKV) infection is a well-nurtured topic for healthcare personnel nowadays. Central nervous system involvement including microcephaly and ocular involvements has already been reported in neonates of affected pregnant ladies. In this article, we have discussed these effects on the newborns of ZIKV-infected mothers. The proposed pathogenesis, modes of transmission of this infection from mothers to the fetuses, diagnosis of the cases and precaution for the pregnant ladies have also been discussed. We have gathered the recently available data on the risk of ZIKV for expectant mothers from PubMed, https://www.gov.uk/guidance/zika-virus as well as from centers for disease control and prevention websites.
authors.affiliation: Department of Internal Medicine, IPGMER, Kolkata, India.
authors.forename: Adrija
authors.initials: A
authors.lastname: Hajra
authors.affiliation: Department of Internal Medicine, St Vincent Charity, Cleveland, OH, USA.
authors.forename: Dhrubajyoti
authors.initials: D
authors.lastname: Bandyopadhyay
authors.affiliation: Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
authors.forename: Lyndsey R
authors.initials: LR
authors.lastname: Heise
authors.affiliation: Department of Internal Medicine, St Vincent Charity Medical Center, A teaching affiliate to, Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Rajarshi
authors.initials: R
authors.lastname: Bhadra
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospital, Kolkata, India.
authors.forename: Somedeb
authors.initials: S
authors.lastname: Ball
authors.affiliation: Department of Internal Medicine, NMB Centre, Serampore, West Bengal, India.
authors.forename: Shyamal Kumar
authors.initials: SK
authors.lastname: Hajra
mesh_terms: D000818:Animals; D002487:Centers for Disease Control and Prevention, U.S.; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology*; D018445:Infectious Disease Transmission, Vertical; D008831:Microcephaly / Q000453:epidemiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D039781:PubMed; D012306:Risk; D014481:United States; D000071244:Zika Virus / Q000502:physiology*; D000071243:Zika Virus Infection / Q000453:epidemiology*
keywords: Zika virus infection; fetal anomaly; microcephaly; pregnancy