title: The effect of exercise induced weight-loss on myokines and adipokines in overweight sedentary females: steps-aerobics vs. jogging-walking exercises.
abstract: BACKGROUND
  The objectives of this study were to verify effects of step-aerobic exercise (SAE) and jogging-walking exercise (JWE) program on myokines and adipokines levels in overweight sedentary females.
  
  
  METHODS
  Volunteer subjects (N.=25) were assigned to two exercise groups: steps aerobics and jogging-walking. The exercise program given to them was for five days a week and for twelve weeks period. Serum samples were collected from venous blood before and immediately after Cardio-Respiratory Fitness Test (CRF) by Bruce protocol and stored at -80 °C until they were assayed before 12 weeks exercise program. After 12-weeks training program this procedure was repeated. Serum TNF-α, IL-6, IL-15, IL-17, IL-18, leptin, resistin and adiponectin levels were assayed by ELISA.
  
  
  RESULTS
  Leptin and IL-15 levels were increased whereas resistin levels were decreased after CRF Test in JWE training group following 12-weeks exercise program. TNF-α, IL-15 and IL-18 levels were higher and leptin levels were lower in SAE group than JWE group after 12-weeks exercise period. However, both SAE and JWE did not lead to significant change in serum levels of IL-17, IL-6 and adiponectin levels.
  
  
  CONCLUSIONS
  This study has added to existing knowledge that both SAE and JWE may cause weight loss especially in fat mass. But, the effect of SAE and JWE on myokines and adipokines levels may be the different. Further studies are needed to find out clinical importance of these findings.
authors.affiliation: Department of Physiology, Medical School, Inonu University, Malatya, Turkey - hduzova@hotmail.com.
authors.forename: Halil
authors.initials: H
authors.lastname: Duzova
authors.affiliation: Physical Education and Sports High School, Inonu University, Malatya, Turkey.
authors.forename: Esin
authors.initials: E
authors.lastname: Gullu
authors.affiliation: Physical Education and Sports High School, Hitit University, Corum, Turkey.
authors.forename: Guner
authors.initials: G
authors.lastname: Cicek
authors.affiliation: Department of Physiology, Medical School, Inonu University, Malatya, Turkey.
authors.forename: Burcu K
authors.initials: BK
authors.lastname: Koksal
authors.affiliation: Department of Medical Biology and Genetics, Inonu University, Medical School, Malatya, Turkey.
authors.forename: Basak
authors.initials: B
authors.lastname: Kayhan
authors.affiliation: Physical Education and Sports High School, Inonu University, Malatya, Turkey.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Gullu
authors.affiliation: Department of Endocrinology, Inonu University, Medical School, Malatya, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Sahin
mesh_terms: D054392:Adipokines / Q000097:blood*; D052242:Adiponectin / Q000097:blood; D000328:Adult; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D019409:Interleukin-15 / Q000097:blood; D020381:Interleukin-17 / Q000097:blood; D020382:Interleukin-18 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D007590:Jogging; D020738:Leptin / Q000097:blood; D050177:Overweight / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D016138:Walking; D015431:Weight Loss
chemical_list: C499918:ADIPOQ protein, human; D054392:Adipokines; D052242:Adiponectin; C508717:IL17A protein, human; D019409:Interleukin-15; D020381:Interleukin-17; D020382:Interleukin-18; D015850:Interleukin-6; D020738:Leptin; D014409:Tumor Necrosis Factor-alpha