title: Divergent Total Synthesis of Atisane-Type Diterpenoids.
abstract: Atisane-type diterpenoids are the principal constituent of tetracyclic C20-diterpenoids, widely isolated from the plant kingdom with varying degrees of structural complexity and pharmacological activity. The tetracarbocyclic system with the unique bicyclo[2.2.2]octane skeleton of this natural product family has generated interest within the synthetic community. Divergent total synthesis is an effective tactic to synthesize several atisane-type diterpenoids using structural interconversion from a common intermediate. This account summarizes the divergent total synthesis of atisane-type diterpenoids.
authors.affiliation: Key Laboratory of Green Chemistry & Technology of the Ministry of Education, College of Chemistry, Sichuan University, No. 29 Wangjiang Road, Chengdu, Sichuan, 610064, P. R. China.
authors.forename: Guili
authors.initials: G
authors.lastname: Zhu
authors.affiliation: Key Laboratory of Green Chemistry & Technology of the Ministry of Education, College of Chemistry, Sichuan University, No. 29 Wangjiang Road, Chengdu, Sichuan, 610064, P. R. China.
authors.forename: Sachin B
authors.initials: SB
authors.lastname: Wadavrao
authors.affiliation: Key Laboratory of Green Chemistry & Technology of the Ministry of Education, College of Chemistry, Sichuan University, No. 29 Wangjiang Road, Chengdu, Sichuan, 610064, P. R. China.|State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjiaxiang, Nanjing, Jiangsu, 210009, P. R. China.
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
keywords: atisane; polycycles; synthesis design; terpenoids; total synthesis