title: Ultra-High-Dose Opioids With Low Efficacy and Significant Harm-Time to Make a Change: A Teachable Moment.
authors.affiliation: Yale University School of Medicine, New Haven, Connecticut.
authors.forename: Paul
authors.initials: P
authors.lastname: Guillod
authors.affiliation: Yale University School of Medicine, New Haven, Connecticut2VA Connecticut Healthcare System, West Haven.
authors.forename: Ellen L
authors.initials: EL
authors.lastname: Edens
authors.affiliation: Yale University School of Medicine, New Haven, Connecticut2VA Connecticut Healthcare System, West Haven.
authors.forename: William C
authors.initials: WC
authors.lastname: Becker
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects* / Q000819:agonists*; D001416:Back Pain / Q000188:drug therapy* / Q000523:psychology; D059350:Chronic Pain / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D005260:Female; D015438:Health Behavior / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D009042:Motivation / Q000187:drug effects*; D010098:Oxycodone / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000701:Analgesics, Opioid; D010098:Oxycodone