title: Plant Food Supplements with Antioxidant Properties for the Treatment of Chronic and Neurodegenerative Diseases: Benefits or Risks?
abstract: Wine by-products, in particular grape pomace, can be an important source of polyphenols and dietary fibers and are increasingly being used as a starting material in the industrial production of plant food supplements, such as other matrices containing biomolecules, with antioxidant properties. The risk associated with the consumption of these products was recently analyzed through a study of potential genotoxic and carcinogenic compounds that can be found in the marketed products. In particular, occurrence data about contamination with the mycotoxin ochratoxin A were also reported. This short review aims at giving an overview about the quality and benefits of these kinds of food supplements, and also about risks of incorrect use, focusing on the emerging need for stricter European regulations.
authors.affiliation: a Dipartimento Farmacia-Scienze del Farmaco , Università degli Studi di Bari "Aldo Moro" , Bari , Italy.|b Istituto di Scienze delle Produzioni Alimentari , Consiglio Nazionale delle Ricerche (ISPA-CNR) , Bari , Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Piemontese
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage / Q000009:adverse effects*; D002908:Chronic Disease / Q000628:therapy*; D019587:Dietary Supplements / Q000009:adverse effects* / Q000592:standards; D005060:Europe; D005506:Food Contamination / Q000032:analysis; D006801:Humans; D019636:Neurodegenerative Diseases / Q000628:therapy*; D009793:Ochratoxins / Q000032:analysis / Q000633:toxicity; D028321:Plant Preparations / Q000008:administration & dosage / Q000009:adverse effects*; D027843:Vitis; D014920:Wine
chemical_list: D000975:Antioxidants; D009793:Ochratoxins; D028321:Plant Preparations; C025589:ochratoxin A
keywords: Alzheimer's disease; chronic diseases; ochratoxin A; plant food supplements; wine by-products