title: Functional and oncological outcome after surgical resection of the scapula and clavicle for primary chondrosarcoma.
abstract: OBJECTIVE
  The scapula is a relatively common site for chondrosarcoma to develop in contrary to the clavicle, which is rarely affected by these tumors. The aim of this study is to determine the functional and oncological outcome for patients treated operatively for scapular or clavicular chondrosarcoma.
  
  
  METHODS
  In this single-center retrospective study, we included a sample of 20 patients that received the diagnosis of a primary chondrosarcoma of the scapula or clavicle. Of the surviving patients, the functional function was assessed using the DASH and the PROMIS Physical Function-Upper Extremity. Patients were longitudinally tracked for their oncological outcome.
  
  
  RESULTS
  All patients were followed for at least 2 years or until death. The mean age of the cohort was 47 years. Eighteen patients suffered from a chondrosarcoma of the scapula, and in 2 patients, the tumor was located in the clavicle. Metastasis, local recurrence and a higher tumor grade were all associated with a decreased overall survival. For the patients with a chondrosarcoma of the scapula, the average DASH score was 16 ± 16 and the mean PROMIS Physical Function-Upper Extremity score was 48 ± 10. Patients with both an intact rotator cuff and glenoid had a better physical function.
  
  
  CONCLUSIONS
  Upper extremity function after (partial) scapulectomy varied depending on whether the glenoid was spared and whether a functioning shoulder abductor remained. When the resection spared these structures, then excellent functional outcomes were reported. Oncologic outcomes depended upon the grade of the tumor and whether local recurrence and metastases occurred.
authors.affiliation: Orthopaedic Oncology Service, Massachusetts General Hospital - Harvard Medical School, Yawkey Center, Suite 3B, 55 Fruit Street, Boston, MA, 02114, USA. snota@mgh.harvard.edu.
authors.forename: S P F T
authors.identifier: http://orcid.org/0000-0002-8807-1457
authors.initials: SP
authors.lastname: Nota
authors.affiliation: Orthopaedic Oncology Service, Massachusetts General Hospital - Harvard Medical School, Yawkey Center, Suite 3B, 55 Fruit Street, Boston, MA, 02114, USA.
authors.forename: M J A M
authors.initials: MJ
authors.lastname: Russchen
authors.affiliation: Orthopaedic Oncology Service, Massachusetts General Hospital - Harvard Medical School, Yawkey Center, Suite 3B, 55 Fruit Street, Boston, MA, 02114, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Raskin
authors.affiliation: Orthopaedic Oncology Service, Massachusetts General Hospital - Harvard Medical School, Yawkey Center, Suite 3B, 55 Fruit Street, Boston, MA, 02114, USA.
authors.forename: H J
authors.initials: HJ
authors.lastname: Mankin
authors.affiliation: Orthopaedic Oncology Service, Massachusetts General Hospital - Harvard Medical School, Yawkey Center, Suite 3B, 55 Fruit Street, Boston, MA, 02114, USA.
authors.forename: F J
authors.initials: FJ
authors.lastname: Hornicek
authors.affiliation: Orthopaedic Oncology Service, Massachusetts General Hospital - Harvard Medical School, Yawkey Center, Suite 3B, 55 Fruit Street, Boston, MA, 02114, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Schwab
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D002813:Chondrosarcoma / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D002968:Clavicle / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D012540:Scapula / Q000601:surgery*; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: Chondrosarcoma; Clavicle; Functional; Outcome; Scapula