title: The mouse Gene Expression Database (GXD): 2017 update.
abstract: The Gene Expression Database (GXD; www.informatics.jax.org/expression.shtml) is an extensive and well-curated community resource of mouse developmental expression information. Through curation of the scientific literature and by collaborations with large-scale expression projects, GXD collects and integrates data from RNA in situ hybridization, immunohistochemistry, RT-PCR, northern blot and western blot experiments. Expression data from both wild-type and mutant mice are included. The expression data are combined with genetic and phenotypic data in Mouse Genome Informatics (MGI) and made readily accessible to many types of database searches. At present, GXD includes over 1.5 million expression results and more than 300 000 images, all annotated with detailed and standardized metadata. Since our last report in 2014, we have added a large amount of data, we have enhanced data and database infrastructure, and we have implemented many new search and display features. Interface enhancements include: a new Mouse Developmental Anatomy Browser; interactive tissue-by-developmental stage and tissue-by-gene matrix views; capabilities to filter and sort expression data summaries; a batch search utility; gene-based expression overviews; and links to expression data from other species.
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Jacqueline H
authors.initials: JH
authors.lastname: Finger
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Constance M
authors.initials: CM
authors.lastname: Smith
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Terry F
authors.initials: TF
authors.lastname: Hayamizu
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Ingeborg J
authors.initials: IJ
authors.lastname: McCright
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Jingxia
authors.initials: J
authors.lastname: Xu
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Meiyee
authors.initials: M
authors.lastname: Law
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: David R
authors.initials: DR
authors.lastname: Shaw
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Richard M
authors.initials: RM
authors.lastname: Baldarelli
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Jon S
authors.initials: JS
authors.lastname: Beal
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Olin
authors.initials: O
authors.lastname: Blodgett
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Jeff W
authors.initials: JW
authors.lastname: Campbell
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Lori E
authors.initials: LE
authors.lastname: Corbani
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Jill R
authors.initials: JR
authors.lastname: Lewis
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Kim L
authors.initials: KL
authors.lastname: Forthofer
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Pete J
authors.initials: PJ
authors.lastname: Frost
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Sharon C
authors.initials: SC
authors.lastname: Giannatto
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Lucie N
authors.initials: LN
authors.lastname: Hutchins
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Dave B
authors.initials: DB
authors.lastname: Miers
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Howie
authors.initials: H
authors.lastname: Motenko
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Stone
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Janan T
authors.initials: JT
authors.lastname: Eppig
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: James A
authors.initials: JA
authors.lastname: Kadin
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Joel E
authors.initials: JE
authors.lastname: Richardson
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA martin.ringwald@jax.org.
authors.forename: Martin
authors.initials: M
authors.lastname: Ringwald
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D015870:Gene Expression; D020869:Gene Expression Profiling / Q000379:methods*; D063990:Gene Ontology; D023281:Genomics / Q000379:methods*; D051379:Mice; D009928:Organ Specificity; D057386:Search Engine; D014584:User-Computer Interface; D064878:Web Browser