title: Multicentric reticulohistiocytosis: Rheumatology perspective.
abstract: Multicentric reticulohistiocytosis (MRH) is a rare, multisystemic non-Langerhans cell histiocytosis characterized by skin and articular involvement, and rarely involves various other organs. There are no specific laboratory findings for MRH. Diagnosis is based on clinical findings and skin or synovial biopsy results. There is currently no consensus for the treatment of MRH. Here, we review the differential diagnosis and treatment options of MRH from the rheumatologist's perspective. We also report an index case of MRH associated with Sjögren's syndrome and pulmonary embolism.
authors.affiliation: Department of Internal Medicine, Division of Rheumatology, Istanbul Faculty of Medicine, Istanbul, Turkey.
authors.forename: Bahtiyar
authors.initials: B
authors.lastname: Toz
authors.affiliation: Department of Pathology, Istanbul School of Medicine, Istanbul, Turkey.
authors.forename: Nesimi
authors.initials: N
authors.lastname: Büyükbabani
authors.affiliation: Department of Internal Medicine, Division of Rheumatology, Istanbul Faculty of Medicine, Istanbul, Turkey. Electronic address: drinanc@istanbul.edu.tr.
authors.forename: Murat
authors.initials: M
authors.lastname: İnanç
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D012219:Rheumatology
keywords: Multicentric reticulohistiocytosis; Non-Langerhans histiocytosis; Papulonodular skin lesions