title: A model for handling cell stress.
abstract: The heat shock response in yeast is regulated by the interaction between a chaperone protein and a heat shock transcription factor, and fine-tuned by phosphorylation.
authors.affiliation: Center for Molecular Biology Heidelberg University, DKFZ-ZMBH-Alliance, Heidelberg, Germany.
authors.forename: Laura
authors.identifier: 0000-0002-5599-3244
authors.initials: L
authors.lastname: Le Breton
authors.affiliation: Center for Molecular Biology Heidelberg University, DKFZ-ZMBH-Alliance, Heidelberg, Germany.
authors.forename: Matthias P
authors.identifier: 0000-0002-7859-3112
authors.initials: MP
authors.lastname: Mayer
mesh_terms: D004268:DNA-Binding Proteins; D000076249:Heat Shock Transcription Factors; D006360:Heat-Shock Proteins; D018869:Heat-Shock Response; D010766:Phosphorylation; D014157:Transcription Factors
chemical_list: D004268:DNA-Binding Proteins; D000076249:Heat Shock Transcription Factors; D006360:Heat-Shock Proteins; D014157:Transcription Factors
keywords: Hsf1; Hsp70; S. cerevisiae; cell biology; chaperone; computational biology; heat shock response; phosphorylation; systems biology; systems modeling