title: Analysis ofHelicobacter pyloriPrevalence in Chittagong, Bangladesh, Based on PCR and CLO Test.
abstract: The pathogenic bacteriumHelicobacter pyloriis a causative agent of gastric diseases in Bangladesh as well as throughout the world. This study aimed at analyzing the prevalence ofH. pyloriinfection among dyspeptic patients in Chittagong, the second most populous city of Bangladesh, using 16S rRNA-basedH. pylori-specific Polymerase Chain Reaction andCampylobacter-like organism test. We found that 67% of the population under study was positive forH. pyloriinfection. Gastric ulcer and duodenal ulcer disease showed statistically significant association withH. pyloriinfection; however, no association ofH. pyloriinfection was observed in terms of age and gender. This study would play a crucial role in managingH. pylori-induced gastric diseases by understanding the current trend ofH. pyloriinfection in the Chittagong region of Bangladesh.
authors.affiliation: Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong, Bangladesh.
authors.forename: Abdul Musaweer
authors.initials: AM
authors.lastname: Habib
authors.affiliation: Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong, Bangladesh.
authors.forename: Md Jibran
authors.initials: MJ
authors.lastname: Alam
authors.affiliation: Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong, Bangladesh.
authors.forename: Bashudev
authors.initials: B
authors.lastname: Rudra
authors.affiliation: Department of Gastroenterology, Chittagong Medical College, Chittagong, Bangladesh.
authors.forename: Md Abdul
authors.initials: MA
authors.lastname: Quader
authors.affiliation: Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong, Bangladesh.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Al-Forkan
keywords: CLO test; H. pylori 16S rRNA; Helicobacter pylori; PCR; gastric diseases