title: Quality-of-life assessment as an outcomes measure in critical limb ischemia.
abstract: Critical limb ischemia (CLI) is a diagnosis plagued by significant comorbidity and high mortality rates. Overall survival remains poor in this population regardless of the procedure-related success as demonstrated by freedom from amputation, intervention, and patency. The literature has traditionally focused on physician-centered and lesion-centered outcomes with regards to limb salvage procedures, but there remains a relative paucity of studies of CLI patients describing patient-centered outcomes such as quality of life (QoL), independent living, and ambulation status. Review of the available literature indicates patients do not always experience significant gains in their QoL after limb salvage interventions, despite reasonable graft patency, amputation-free survival, and limb salvage rates. Further research is required using QoL tools in a measurable and clinically relevant fashion to guide optimal quality care that maximizes patient-centered outcomes.
authors.affiliation: Division of Vascular and Endovascular Surgery, Oregon Health & Science University, Portland, Ore. Electronic address: o.alabi82@gmail.com.
authors.forename: Olamide
authors.initials: O
authors.lastname: Alabi
authors.affiliation: Division of Vascular and Endovascular Surgery, Oregon Health & Science University, Portland, Ore.
authors.forename: Matthew
authors.initials: M
authors.lastname: Roos
authors.affiliation: Division of Vascular and Endovascular Surgery, Oregon Health & Science University, Portland, Ore.
authors.forename: Gregory
authors.initials: G
authors.lastname: Landry
authors.affiliation: Division of Vascular and Endovascular Surgery, Oregon Health & Science University, Portland, Ore.
authors.forename: Gregory
authors.initials: G
authors.lastname: Moneta
mesh_terms: D016638:Critical Illness; D057510:Endovascular Procedures / Q000009:adverse effects / Q000401:mortality; D006801:Humans; D000071066:Patient Reported Outcome Measures; D058729:Peripheral Arterial Disease / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D011237:Predictive Value of Tests; D011788:Quality of Life; D020127:Recovery of Function; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality