title: METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH.
abstract: Science is not done in a vacuum - across fields of biomedicine, scientists have built on previous research and used data published in previous papers. A mainstay of scientific inquiry is the publication of one's research and recognition for this work is given in the form of citations and notoriety - ideally given in proportion to the quality of the work. Academic incentives, however, may encourage individual researchers to prioritize career ambitions over scientific truth. Recently, the New England Journal of Medicine published a commentary calling scientists who repurpose data "research parasites" who misuse data generated by others to demonstrate alternative hypotheses. In our opinion, the concept of data hoarding not only runs contrary to the spirit of, but also hinders scientific progress. Scientific research is meant to seek objective truth, rather than promote a personal agenda, and the only way to do so is through maximum transparency and reproducibility, no matter who is using the data….
authors.affiliation: Massachusetts General Hospital, Boston, MA, USA2Broad Institute, Cambridge, MA, USA, konradjkarczewski@gmail.com.
authors.forename: Konrad J
authors.initials: KJ
authors.lastname: Karczewski
authors.forename: Nicholas P
authors.initials: NP
authors.lastname: Tatonetti
authors.forename: Arjun K
authors.initials: AK
authors.lastname: Manrai
authors.forename: Chirag J
authors.initials: CJ
authors.lastname: Patel
authors.forename: C
authors.initials: C
authors.lastname: Titus Brown
authors.forename: John P A
authors.initials: JPA
authors.lastname: Ioannidis