title: Dengue Infection in a Human Immunodeficiency Virus-1 Positive Patient Chronically Infected with Hepatitis B Virus in Western Mexico.
abstract: Human immunodeficiency virus (HIV) and dengue coinfection has not been extensively studied. We report herein a case of dengue serotype 1 infection in an HIV-1-positive patient coinfected with hepatitis B virus (HBV) in Colima State, Mexico. CD4+cells and HIV-1 viremia remained at normal levels, and no severe complications were observed during this multiple viral infection. The alanine transaminase and aspartate transaminase values were elevated before and during dengue infection. Surprisingly, these parameters were significantly reduced 2 months later. Because of the lack of evidence regarding this multiple viral interaction, further research is required to understand the biologic and clinical course of dengue infection in HIV-1/HBV coinfected patients, especially in tropical regions where dengue virus transmission is highly active.
authors.affiliation: School of Medicine, University of Colima, Colima, México.|State Cancer Institute, Department of Health, Colima, México.
authors.forename: Iván
authors.initials: I
authors.lastname: Delgado-Enciso
authors.affiliation: School of Medicine, University of Colima, Colima, México.|Department of Internal Medicine, Regional Hospital of Colima, Department of Health, Colima, México.
authors.forename: Francisco
authors.initials: F
authors.lastname: Espinoza-Gómez
authors.affiliation: Department of Internal Medicine, Regional Hospital of Colima, Department of Health, Colima, México.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Ochoa-Jiménez
authors.affiliation: School of Medicine, University of Colima, Colima, México.
authors.forename: Salvador
authors.initials: S
authors.lastname: Valle-Reyes
authors.affiliation: School of Medicine, University of Colima, Colima, México.
authors.forename: Clemente
authors.initials: C
authors.lastname: Vásquez
authors.affiliation: School of Medicine, University of Colima, Colima, México. lemus_a83@yahoo.com.|Center for Gene Therapy, Hematologic Malignancies and Stem Cell Transplantation Institute, City of Hope, Duarte, California.
authors.forename: Uriel A
authors.initials: UA
authors.lastname: López-Lemus
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D003715:Dengue / Q000150:complications*; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000821:virology*; D015497:HIV-1; D019694:Hepatitis B, Chronic / Q000150:complications*; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D014766:Viremia
chemical_list: D019380:Anti-HIV Agents