title: 3D carbon nanofiber microelectrode arrays fabricated by plasma-assisted pyrolysis to enhance sensitivity and stability of real-time dopamine detection.
abstract: In this paper, we have fabricated 3D carbon nanofiber microelectrode arrays (MEAs) with highly reproducible and rich chemical surface areas for fast scan cyclic voltammetry (FSCV). Carbon nanofibers are created from negative photoresist by a new process called dual O2plasma-assisted pyrolysis. The proposed approach significantly improves film adhesion and increases surface reactivity. We showcase our sensor's compatibility with FSCV analysis by demonstrating highly sensitive and stable FSCV dopamine measurements on a prototype 4-channel array. We envision with proper surface fuctionalization the 3D carbon nanofiber MEA enable sensitive and reliable detection of multiple neurotransmitters simultaneously.
authors.affiliation: Department of Electrical and Computer Engineering, Wayne State University, 5050 Anthony Wayne Drive, Detroit, MI, 48202, USA.
authors.forename: Wenwen
authors.initials: W
authors.lastname: Yi
authors.affiliation: Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI, 48202, USA.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, SC, 29208, USA.
authors.forename: Parastoo
authors.initials: P
authors.lastname: Hashemi
authors.affiliation: Department of Electrical and Computer Engineering, Wayne State University, 5050 Anthony Wayne Drive, Detroit, MI, 48202, USA. mcheng@wayne.edu.
authors.forename: Mark Ming-Cheng
authors.initials: MM
authors.lastname: Cheng
mesh_terms: D002138:Calibration; D002244:Carbon / Q000737:chemistry*; D004298:Dopamine / Q000032:analysis*; D004563:Electrochemistry; D057230:Limit of Detection; D008839:Microelectrodes; D057139:Nanofibers / Q000737:chemistry*; D036103:Nanotechnology / Q000295:instrumentation*; D010100:Oxygen / Q000737:chemistry; D058626:Plasma Gases / Q000737:chemistry*; D013997:Time Factors
chemical_list: D058626:Plasma Gases; D002244:Carbon; D010100:Oxygen; D004298:Dopamine
keywords: Carbon nanofiber; Dopamine; FSCV; Plasma-assisted pyrolysis