title: [Prevention of the recurrent herpetic stomatitis in employees of Kazan city industrial enterprises frequently suffering from acute respiratory viral infections].
abstract: Research objective was to study the efficacy of ingavirin for prevention of recurrent herpetic stomatitis in employees of Kazan city industrial enterprises frequently suffering from acute respiratory viral infections. 128 employees aged from 18 to 56 years were included in the study. Clinical and immunological efficiency of ingavirin prevention of recurrent herpetic stomatitis is proved by estimation of oral cavity local immunity (SlgA, lisozyme), humoral immunity (IgE and IgG) and cellular immunity (RBTL with FGA, defined T-lymphocytes). After administration of ingavirin significant (p<0.05) increase of lisozyme and SlgA, RBTL with FGA, number of T-lymphocytes and IgG concentration was observed. The obtained data allow to recommend ingavirin for prevention of recurrent herpetic stomatitis.
authors.affiliation: Kazan National Research Technological University, Kazan, Russia, Moscow State Medical Dental University named after A.I. Evdokimov, Moscow, Russia.
authors.forename: O Yu
authors.initials: OY
authors.lastname: Kuznetzova
authors.affiliation: Kazan National Research Technological University, Kazan, Russia, Moscow State Medical Dental University named after A.I. Evdokimov, Moscow, Russia.
authors.forename: A P
authors.initials: AP
authors.lastname: Gorshenina
authors.affiliation: Kazan National Research Technological University, Kazan, Russia, Moscow State Medical Dental University named after A.I. Evdokimov, Moscow, Russia.
authors.forename: L N
authors.initials: LN
authors.lastname: Maximovskaya
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001426:Bacterial Proteins / Q000032:analysis / Q000276:immunology; D002208:Caproates / Q000008:administration & dosage*; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage*; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007221:Industry; D008213:Lymphocyte Activation; D018655:Lymphocyte Count; D008875:Middle Aged; D009055:Mouth / Q000276:immunology; D009113:Muramidase / Q000032:analysis; D010835:Phytohemagglutinins / Q000276:immunology; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology*; D055502:Secondary Prevention; D013283:Stomatitis, Herpetic / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control*; D013601:T-Lymphocytes / Q000276:immunology; D064874:Tatarstan / Q000453:epidemiology; D000078329:Workforce; D055815:Young Adult
chemical_list: D001426:Bacterial Proteins; D002208:Caproates; D007093:Imidazoles; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D010835:Phytohemagglutinins; C070683:surface layer protein A, Bacteria; C539419:pentanedioic acid imidazolyl ethanamide; D009113:Muramidase; C514728:lysozyme C, human