title: Effect of Natural and 24-h Illumination on Mesenchymal Stem Cells.
abstract: We studied the effect 24-h illumination on quantitative and qualitative parameters of the bone marrow cells in Wistar rats. It was shown that desynchronosis reduced the release of nucleated cells from the femoral bone, while melatonin weakened this effect. The number of bone marrow mesenchymal stromal cells was resistant to circadian rhythm disturbances, while proliferation depended on glucose concentration in the medium.
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia. aplykov2@mail.ru.
authors.forename: A P
authors.initials: AP
authors.lastname: Lykov
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Bondarenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Surovtseva
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: I I
authors.initials: II
authors.lastname: Kim
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Poveshchenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: I Yu
authors.initials: IY
authors.lastname: Ishchenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Kabakov
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Kazakov
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: A F
authors.initials: AF
authors.lastname: Poveshchenko
authors.affiliation: Federal Research Institute Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
authors.forename: E L
authors.initials: EL
authors.lastname: Zav'yalov
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: S V
authors.initials: SV
authors.lastname: Michurina
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Konenkov
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects*; D002452:Cell Count; D049109:Cell Proliferation / Q000187:drug effects / Q000528:radiation effects*; D003470:Culture Media / Q000494:pharmacology; D005947:Glucose / Q000378:metabolism / Q000494:pharmacology; D008027:Light; D008297:Male; D008550:Melatonin / Q000494:pharmacology; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects*; D017440:Photoperiod; D051381:Rats; D017208:Rats, Wistar
chemical_list: D003470:Culture Media; D005947:Glucose; D008550:Melatonin
keywords: bone marrow mesenchymal stem cells; melatonin; natural and 24-h illumination; proliferation