title: Efficacy of tigecycline-colistin combination in the treatment of carbapenem-resistant Klebsiella pneumoniae endocarditis.
abstract: Here we discuss the efficacy of colistin-tigecycline combination in the treatment of multidrug-resistant (MDR) Klebsiella pneumoniae infective endocarditis (IE). We report a case of a 67-year-old head-injured patient who developed a carbapenem-resistant K. pneumoniae IE. The patient was treated with colistin-tigecycline combination, with a favourable outcome. In conclusion, colistin-tigecycline combination may be a possible combination in the therapy of IE caused by MDR Enterobacteriaceae.
authors.affiliation: Department of Intensive Care, Habib Bourguiba University Hospital, Road El Ain km 0.5, Sfax 3029, Tunisia. Electronic address: anischaari2004@yahoo.fr.
authors.forename: Anis
authors.initials: A
authors.lastname: Chaari
authors.affiliation: Department of Microbiology, Habib Bourguiba University Hospital, Sfax, Tunisia.
authors.forename: Basma
authors.initials: B
authors.lastname: Mnif
authors.affiliation: Department of Intensive Care, Habib Bourguiba University Hospital, Road El Ain km 0.5, Sfax 3029, Tunisia.
authors.forename: Kamilia
authors.initials: K
authors.lastname: Chtara
authors.affiliation: Department of Cardiology, Habib Bourguiba University Hospital, Sfax, Tunisia.
authors.forename: Leila
authors.initials: L
authors.lastname: Abid
authors.affiliation: Department of Cardiology, Habib Bourguiba University Hospital, Sfax, Tunisia.
authors.forename: Salma
authors.initials: S
authors.lastname: Charfeddine
authors.affiliation: Department of Intensive Care, Habib Bourguiba University Hospital, Road El Ain km 0.5, Sfax 3029, Tunisia.
authors.forename: Najeh
authors.initials: N
authors.lastname: Baccouche
authors.affiliation: Department of Intensive Care, Habib Bourguiba University Hospital, Road El Ain km 0.5, Sfax 3029, Tunisia.
authors.forename: Mabrouk
authors.initials: M
authors.lastname: Bahloul
authors.affiliation: Department of Microbiology, Habib Bourguiba University Hospital, Sfax, Tunisia.
authors.forename: Adnène
authors.initials: A
authors.lastname: Hammami
authors.affiliation: Department of Intensive Care, Habib Bourguiba University Hospital, Road El Ain km 0.5, Sfax 3029, Tunisia.
authors.forename: Mounir
authors.initials: M
authors.lastname: Bouaziz
keywords: Carbapenem-resistant Klebsiella pneumoniae; Colistin; Endocarditis; Tigecycline