title: ACTH therapy for West syndrome with severe hemophilia A.
abstract: Hemophilia A is an X-linked recessive disorder caused by factor VIII deficiency, which is an important factor in the coagulation system. Here, we describe a 1-year-old boy with hemophilia A who developed West syndrome (WS). Recombinant factor VIII was administered during adrenocorticotropic hormone (ACTH) therapy to prevent intracranial hemorrhage. Infusion of factor VIII at fixed intervals is useful for the safe administration of ACTH therapy for patients with WS with severe hemophilia A. A coagulation screening test should be performed before ACTH therapy.
authors.affiliation: Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kubota
authors.affiliation: Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Kinomura
authors.affiliation: Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yamamoto
authors.affiliation: Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Michio
authors.initials: M
authors.lastname: Ozeki
authors.affiliation: Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Minako
authors.initials: M
authors.lastname: Kawamoto
authors.affiliation: Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Kawamoto
authors.affiliation: Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Fukao
keywords: ACTH; Coagulopathy; Hemophilia A; West syndrome