title: Combining Organocatalysis and Lanthanide Catalysis: A Sequential One-Pot Quadruple Reaction Sequence/Hetero-Diels-Alder Asymmetric Synthesis of Functionalized Tricycles.
abstract: A stereoselective one-pot synthesis of functionalized complex tricyclic polyethers has been achieved using the combination of secondary amine and lanthanide catalysis. This one-pot quadruple reaction/Hetero-Diels-Alder sequence gave good yields (per step) as well as excellent diastereo- and enantioselectivities. Furthermore, the particular combination of lanthanide complexes with organocatalysis is one of the first examples described for sequential catalysis.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Simon
authors.initials: S
authors.lastname: Dochain
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Vetica
authors.affiliation: Department of Chemistry, Nanoscience Center, University of Jyvaskyla, 40014 JYU, Finland.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Puttreddy
authors.affiliation: Department of Chemistry, Nanoscience Center, University of Jyvaskyla, 40014 JYU, Finland.
authors.forename: Kari
authors.initials: K
authors.lastname: Rissanen
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Dieter
authors.initials: D
authors.lastname: Enders
keywords: asymmetric catalysis; heterocycles; lanthanides; organocatalysis; synthetic methods