title: Esophageal tuberculosis with coexisting opportunistic infections in a renal allograft transplant recipient.
abstract: We report a renal allograft transplant recipient with esophageal tuberculosis (TB) coinfected with herpes simplex virus (HSV) and Candida. The patient presented with oropharyngeal candidiasis and was started on fluconazole. Upper gastrointestinal endoscopy showed whitish patches with mucosal ulcers in the esophagus. Histopathological examination confirmed TB and HSV infection. The patient recovered after antiviral, antifungal, and anti-tubercular therapy with reduction in immunosuppression. In a TB-endemic zone, TB can coexist with opportunistic infections in an immunocompromised host.
authors.affiliation: Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Mukut
authors.initials: M
authors.lastname: Minz
authors.affiliation: Department of Gastroenterology, PGIMER, Chandigarh, India.
authors.forename: Saroj K
authors.initials: SK
authors.lastname: Sinha
authors.affiliation: Department of Histopathology, PGIMER, Chandigarh, India.
authors.forename: Kim
authors.initials: K
authors.lastname: Vaiphei
authors.affiliation: Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Sarbpreet
authors.initials: S
authors.lastname: Singh
authors.affiliation: Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Deepesh B
authors.initials: DB
authors.lastname: Kenwar
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002180:Candidiasis, Oral / Q000188:drug therapy / Q000382:microbiology; D003680:Deglutition Disorders / Q000209:etiology; D016099:Endoscopy, Gastrointestinal; D000071041:Esophageal Mucosa / Q000473:pathology; D004941:Esophagitis / Q000150:complications* / Q000382:microbiology / Q000473:pathology / Q000821:virology; D015725:Fluconazole / Q000627:therapeutic use; D006561:Herpes Simplex / Q000150:complications* / Q000473:pathology / Q000821:virology; D006606:Hiccup / Q000209:etiology; D006801:Humans; D016867:Immunocompromised Host; D007150:Immunohistochemistry; D007165:Immunosuppression Therapy / Q000009:adverse effects* / Q000379:methods; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications* / Q000382:microbiology / Q000473:pathology / Q000821:virology; D018139:Simplexvirus / Q000302:isolation & purification; D066027:Transplant Recipients; D014184:Transplantation, Homologous / Q000009:adverse effects; D014385:Tuberculosis, Gastrointestinal / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D014839:Vomiting / Q000209:etiology
chemical_list: D000935:Antifungal Agents; D000995:Antitubercular Agents; D000998:Antiviral Agents; D015725:Fluconazole
keywords: 
  Candida albicans
  ; esophageal tuberculosis; herpes simplex virus; infectious esophagitis; renal transplantation