title: Headgroup engineering in mechanosensitive membrane probes.
abstract: Systematic headgroup engineering yields planarizable push-pull flipper probes that are ready for use in biology - stable, accessible, modifiable -, and affords non-trivial insights into chalcogen-bond mediated mechanophore degradation and fluorescence enhancement.
authors.affiliation: NCCR Chemical Biology, School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
authors.forename: Saeideh
authors.initials: S
authors.lastname: Soleimanpour
authors.affiliation: NCCR Chemical Biology, School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
authors.forename: Adai
authors.initials: A
authors.lastname: Colom
authors.affiliation: NCCR Chemical Biology, School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Derivery
authors.affiliation: NCCR Chemical Biology, School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
authors.forename: Marcos
authors.initials: M
authors.lastname: Gonzalez-Gaitan
authors.affiliation: NCCR Chemical Biology, School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
authors.forename: Aurelien
authors.initials: A
authors.lastname: Roux
authors.affiliation: NCCR Chemical Biology, School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
authors.forename: Naomi
authors.initials: N
authors.lastname: Sakai
authors.affiliation: NCCR Chemical Biology, School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
authors.forename: Stefan
authors.identifier: http://orcid.org/0000-0002-8537-8349
authors.initials: S
authors.lastname: Matile
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation*; D004285:Dogs; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D061985:Madin Darby Canine Kidney Cells; D018613:Microscopy, Confocal; D008958:Models, Molecular
chemical_list: D005456:Fluorescent Dyes