title: Medicinal uses, chemistry and pharmacology of Dillenia species (Dilleniaceae).
abstract: The genus Dillenia is comprised of about 100 species of evergreen and deciduous trees or shrubs of disjunct distribution in the seasonal tropics of Madagascar through South and South East Asia, Malaysia, North Australia, and Fiji. Species from this genus have been widely used in medicinal folklore to treat cancers, wounds, jaundice, fever, cough, diabetes mellitus, and diarrhea as well as hair tonics. The plants of the genus also produce edible fruits and are cultivated as ornamental plants. Flavonoids, triterpenoids, and miscellaneous compounds have been identified in the genus. Their extracts and pure compounds have been reported for their antimicrobial, anti-inflammatory, cytotoxic, antidiabetes, antioxidant, antidiarrheal, and antiprotozoal activities. Mucilage from their fruits is used in drug formulations.
authors.affiliation: Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.
authors.forename: Carla W
authors.initials: CW
authors.lastname: Sabandar
authors.affiliation: Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia. Electronic address: juriyatijalil@ukm.edu.my.
authors.forename: Juriyati
authors.initials: J
authors.lastname: Jalil
authors.affiliation: Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia.
authors.forename: Norizan
authors.initials: N
authors.lastname: Ahmat
authors.affiliation: Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.
authors.forename: Nor-Ashila
authors.initials: NA
authors.lastname: Aladdin
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D001315:Australia; D045466:Dilleniaceae / Q000737:chemistry*; D005367:Fiji; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D008270:Madagascar; D008296:Malaysia; D010936:Plant Extracts / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D005419:Flavonoids; D010936:Plant Extracts; D014315:Triterpenes
keywords: Dillenia; Dilleniaceae; Medicinal uses; Pharmacology; Phytochemical