title: Activation and reduction of carbon dioxide by nitrogenase iron proteins.
abstract: The iron (Fe) proteins of molybdenum (Mo) and vanadium (V) nitrogenases mimic carbon monoxide (CO) dehydrogenase in catalyzing the interconversion between CO2and CO under ambient conditions. Catalytic reduction of CO2to CO is achieved in vitro and in vivo upon redox changes of the Fe-protein-associated [Fe4S4] clusters. These observations establish the Fe protein as a model for investigation of CO2activation while suggesting its biotechnological adaptability for recycling the greenhouse gas into useful products.
authors.affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, USA.
authors.forename: Johannes G
authors.identifier: 0000-0003-2560-716X
authors.initials: JG
authors.lastname: Rebelein
authors.affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, USA.
authors.forename: Martin T
authors.initials: MT
authors.lastname: Stiebritz
authors.affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, USA.
authors.forename: Chi Chung
authors.initials: CC
authors.lastname: Lee
authors.affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, USA.
authors.forename: Yilin
authors.initials: Y
authors.lastname: Hu
mesh_terms: D016948:Azotobacter vinelandii / Q000201:enzymology; D055162:Biocatalysis; D002245:Carbon Dioxide / Q000737:chemistry / Q000378:metabolism*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: D002245:Carbon Dioxide; D010088:Oxidoreductases; C029130:nitrogenase reductase