title: The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog).
abstract: The NHGRI-EBI GWAS Catalog has provided data from published genome-wide association studies since 2008. In 2015, the database was redesigned and relocated to EMBL-EBI. The new infrastructure includes a new graphical user interface (www.ebi.ac.uk/gwas/), ontology supported search functionality and an improved curation interface. These developments have improved the data release frequency by increasing automation of curation and providing scaling improvements. The range of available Catalog data has also been extended with structured ancestry and recruitment information added for all studies. The infrastructure improvements also support scaling for larger arrays, exome and sequencing studies, allowing the Catalog to adapt to the needs of evolving study design, genotyping technologies and user needs in the future.
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: MacArthur
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Emily
authors.initials: E
authors.lastname: Bowler
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Maria
authors.initials: M
authors.lastname: Cerezo
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Laurent
authors.initials: L
authors.lastname: Gil
authors.affiliation: Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Peggy
authors.initials: P
authors.lastname: Hall
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Emma
authors.identifier: 0000-0001-9927-8560
authors.initials: E
authors.lastname: Hastings
authors.affiliation: Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Heather
authors.initials: H
authors.lastname: Junkins
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Aoife
authors.initials: A
authors.lastname: McMahon
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Annalisa
authors.initials: A
authors.lastname: Milano
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Joannella
authors.initials: J
authors.lastname: Morales
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Zoe May
authors.initials: ZM
authors.lastname: Pendlington
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Danielle
authors.initials: D
authors.lastname: Welter
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Tony
authors.identifier: 0000-0002-2513-5396
authors.initials: T
authors.lastname: Burdett
authors.affiliation: Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Lucia
authors.initials: L
authors.lastname: Hindorff
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Paul
authors.identifier: 0000-0002-3897-7955
authors.initials: P
authors.lastname: Flicek
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
authors.forename: Fiona
authors.identifier: 0000-0002-7445-2419
authors.initials: F
authors.lastname: Cunningham
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK parkinson@ebi.ac.uk.
authors.forename: Helen
authors.initials: H
authors.lastname: Parkinson
mesh_terms: D057225:Data Mining; D030561:Databases, Nucleic Acid; D055106:Genome-Wide Association Study / Q000379:methods*; D023281:Genomics / Q000379:methods; D006801:Humans; D058977:Molecular Sequence Annotation; D054560:National Human Genome Research Institute (U.S.); D012984:Software; D014481:United States; D014584:User-Computer Interface; D064878:Web Browser