title: Oral features and computerized rehabilitation of a young patient with CHARGE syndrome using minimally invasive long-term interim CAD-CAM restorations.
abstract: Patients with CHARGE syndrome (where CHARGE stands for coloboma of the iris or retina, heart defects or cardiac malformations, atresia/stenosis of the choanae, retardation of growth and development, genital anomalies, and ear abnormalities) present several orofacial anomalies. Their treatment depends on the specific type of manifestation. To perform the complex oral rehabilitation and achieve a conservative, esthetic, and functional exploration of the definitive treatment goal, computer-aided design and computer-aided manufacturing (CAD-CAM) polymers can be used as long-term interim restorations. This article reports the treatment of a young patient with CHARGE syndrome combined with oral alterations. CAD-CAM polymers offer an intermediate treatment with satisfying esthetics and function at low biological cost until bone growth is completed. This period facilitates additional planning for the definitive restoration.
authors.affiliation: Assistant Professor, Department of Prosthodontics, Dental School, Ludwig-Maximilians University, Munich, Germany. Electronic address: Anja.Liebermann@med.uni-muenchen.de.
authors.forename: Anja
authors.initials: A
authors.lastname: Liebermann
authors.affiliation: Doctoral student, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil; and Guest Dentist, Department of Prosthodontics, Dental School, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Caroline Freitas
authors.initials: CF
authors.lastname: Rafael
authors.affiliation: Head and Chair, Department of Prosthodontics, Dental School, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Edelhoff
authors.affiliation: Certified dental technician, Department of Prosthodontics, Dental School, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Marc
authors.initials: M
authors.lastname: Ramberger
authors.affiliation: Master dental technician, Department of Prosthodontics, Dental School, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Josef
authors.initials: J
authors.lastname: Schweiger
authors.affiliation: Associate Professor, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil.
authors.forename: Claudia Angela
authors.initials: CA
authors.lastname: Maziero Volpato
authors.affiliation: Assistant Professor, Department of Prosthodontics, Dental School, Ludwig-Maximilians University, Munich, Germany.
authors.forename: Reza
authors.initials: R
authors.lastname: Saeidi Pour
mesh_terms: D000293:Adolescent; D058747:CHARGE Syndrome / Q000601:surgery*; D017076:Computer-Aided Design; D017267:Dental Prosthesis Design / Q000379:methods*; D003801:Dental Veneers; D003830:Denture, Partial, Fixed; D004955:Esthetics, Dental; D006801:Humans; D008297:Male; D009065:Mouth Rehabilitation / Q000379:methods*