title: Erythroplasia of Queyrat treated with methyl aminolevulinate-photodynamic therapy.
abstract: Erythroplasia of Queyrat (EQ) is a rare disease involving the mucosal and transitional surfaces of the penis. Effective treatment is necessary to minimize progression to squamous cell carcinoma. The standard therapy for EQ, partial or radical penectomy, is invasive; photodynamic therapy (PDT) may be an effective, non-surgical tissue-sparing option. We report the case of a 67-year-old patient with long-standing EQ who was suc-cessfully treated with methyl aminolevulinate-PDT (MAL-PDT). A complete clinical response, confirmedby incisional biopsy, was achieved af-ter fivesessions of every-other-week treatment. The patient experienced moderate edema, erythema and pain within 5-7 days after the treatment, without urination problems. Our experience and a review of the published literature suggest that MAL-PDT may represent a valuable treatment option for selected cases of histopathologically-confirmed EQ.
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Nevena
authors.initials: N
authors.lastname: Skroza
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Giorgio
authors.initials: G
authors.lastname: La Viola
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy - riccardopampena@gmail.com.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Pampena
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Proietti
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Bernardini
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Ersilia
authors.initials: E
authors.lastname: Tolino
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Annetta
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Zuber
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Veronica
authors.initials: V
authors.lastname: Balduzzi
authors.affiliation: &quot;Daniele Innocenzi&quot; Unit of Dermatology, Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University, Polo Pontino, Terracina, Latina, Italy.
authors.forename: Concetta
authors.initials: C
authors.lastname: Potenza
mesh_terms: D000368:Aged; D000622:Aminolevulinic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004919:Erythroplasia / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D010409:Penile Diseases / Q000188:drug therapy* / Q000473:pathology; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D017319:Photosensitizing Agents; C475457:methyl 5-aminolevulinate; D000622:Aminolevulinic Acid