title: Diastereoselective synthesis of trifluoromethylated 1,3-dioxanes by intramolecular oxa-Michael reaction.
abstract: A highly diastereoselective synthesis of trifluoromethylated 1,3-dioxanes is described. The reaction proceeds by an addition/oxa-Michael sequence and works efficiently under mild reaction conditions, with a good substrate scope and acceptable to good yields.
authors.affiliation: Laboratory of Organic Synthesis, Bio and Organocatalysis, Chemistry Department, Universidad de los Andes, Cra 1 No. 18A-12 Q:305, Bogotá 111711, Colombia. joelle.prunet@glasgow.ac.uk da.gamba1361@uniandes.edu.co.
authors.forename: Liliana
authors.initials: L
authors.lastname: Becerra-Figueroa
authors.affiliation: WestCHEM, School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
authors.forename: Elodie
authors.initials: E
authors.lastname: Brun
authors.affiliation: WestCHEM, School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
authors.forename: Michael
authors.initials: M
authors.lastname: Mathieson
authors.affiliation: WestCHEM, School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
authors.forename: Louis J
authors.initials: LJ
authors.lastname: Farrugia
authors.affiliation: WestCHEM, School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
authors.forename: Claire
authors.initials: C
authors.lastname: Wilson
authors.affiliation: WestCHEM, School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, UK.
authors.forename: Joëlle
authors.initials: J
authors.lastname: Prunet
authors.affiliation: Laboratory of Organic Synthesis, Bio and Organocatalysis, Chemistry Department, Universidad de los Andes, Cra 1 No. 18A-12 Q:305, Bogotá 111711, Colombia. joelle.prunet@glasgow.ac.uk da.gamba1361@uniandes.edu.co.
authors.forename: Diego
authors.identifier: http://orcid.org/0000-0001-5432-5108
authors.initials: D
authors.lastname: Gamba-Sánchez