title: Complex regional pain syndrome associated with hyperattention rather than neglect for the healthy side: A comprehensive case study.
abstract: Complex regional pain syndrome (CRPS) is a dehabilitating chronic condition occurring with peripheral lesions. There is growing consensus for a central contribution to CRPS. Although the nature of this central body representation disorder is increasingly debated, it has been repeatedly argued that CRPS results in motor neglect of the affected side. The present article describes a comprehensive and quantitative case report demonstrating that: (1) not all patients with chronic CRPS exhibit decreased spatial attention for the affected side and (2) patients may actually exhibit a substantial, broad and reliable attentional bias toward the painful side, akin to spatial neglect for the healthy side. This unexpected result agrees with the idea that patients can be hyper-attentive toward their pathological side as a manifestation of lowered pain threshold, allodynia and kinesiophobia.
authors.affiliation: Plate-forme 'Mouvement et Handicap' and Neuro-Immersion, Hôpital Henry-Gabrielle and Hôpital neurologique, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Service de rééducation neurologique, pavillon Bourret, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neurosciences de Lyon, université Lyon-1, 16, avenue Lépine, 69676 Bron, France.
authors.forename: Laure
authors.initials: L
authors.lastname: Christophe
authors.affiliation: Service de rééducation neurologique, pavillon Bourret, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neurosciences de Lyon, université Lyon-1, 16, avenue Lépine, 69676 Bron, France.
authors.forename: Ludovic
authors.initials: L
authors.lastname: Delporte
authors.affiliation: Plate-forme 'Mouvement et Handicap' and Neuro-Immersion, Hôpital Henry-Gabrielle and Hôpital neurologique, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neurosciences de Lyon, université Lyon-1, 16, avenue Lépine, 69676 Bron, France.
authors.forename: Patrice
authors.initials: P
authors.lastname: Revol
authors.affiliation: Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neurosciences de Lyon, université Lyon-1, 16, avenue Lépine, 69676 Bron, France; Department of Experimental Clinical and Health psychology, Universiteit Ghent, H. Dunantlaan 2, 9000 Ghent, Belgium.
authors.forename: Annick
authors.initials: A
authors.lastname: DePaepe
authors.affiliation: Plate-forme 'Mouvement et Handicap' and Neuro-Immersion, Hôpital Henry-Gabrielle and Hôpital neurologique, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Service de rééducation neurologique, pavillon Bourret, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neurosciences de Lyon, université Lyon-1, 16, avenue Lépine, 69676 Bron, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Rode
authors.affiliation: Plate-forme 'Mouvement et Handicap' and Neuro-Immersion, Hôpital Henry-Gabrielle and Hôpital neurologique, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Service de rééducation neurologique, pavillon Bourret, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neurosciences de Lyon, université Lyon-1, 16, avenue Lépine, 69676 Bron, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Jacquin-Courtois
authors.affiliation: Plate-forme 'Mouvement et Handicap' and Neuro-Immersion, Hôpital Henry-Gabrielle and Hôpital neurologique, Hospices Civils de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neurosciences de Lyon, université Lyon-1, 16, avenue Lépine, 69676 Bron, France. Electronic address: yves.rossetti@inserm.fr.
authors.forename: Yves
authors.initials: Y
authors.lastname: Rossetti
mesh_terms: D000070379:Attentional Bias; D005260:Female; D006801:Humans; D008875:Middle Aged; D059352:Musculoskeletal Pain / Q000209:etiology / Q000523:psychology*; D010147:Pain Measurement; D010468:Perceptual Disorders / Q000209:etiology / Q000523:psychology*; D012019:Reflex Sympathetic Dystrophy / Q000209:etiology / Q000523:psychology*
keywords: ADL; Body representation; CRPS; Motor neglect; Pain; Prism adaptation; Reference frame; Spatial neglect