title: Tensile Comparison of Polydioxanone, Polyglyconate, and Barbed Glycolide-Trimethylene Carbonate Suture in Canine Cadaveric Tensor Fascia Lata.
abstract: OBJECTIVE
  To compare the mode of failure, load at yield, ultimate load to failure and stiffness of non-barbed polydioxanone, non-barbed polyglyconate and barbed glycolide-trimethylene carbonate (GTC) suture in canine cadaveric fascia.
  
  
  METHODS
  Ex vivo biomechanical study.
  
  
  METHODS
  18 fascia lata specimens from 9 canine cadavers.
  
  
  METHODS
  6 fascia lata specimens were sutured with polydioxanone, 6 with polyglyconate, and 6 with barbed GTC suture. Load at yield, stiffness, ultimate load to failure were measured using tensile strength testing. Statistical analysis was used to compare outcomes between suture materials. The mode of failure was recorded and described.
  
  
  RESULTS
  The load at yield and ultimate load to failure were significantly greater for polydioxanone than barbed GTC (P=.045 and P=.016, respectively). The load at yield and ultimate load to failure was not significantly different between polydioxanone and polyglyconate (P=.687 and P=.586, respectively). The load at yield and the ultimate load to failure was not significantly different between polyglyconate and barbed GTC (P=.194 and P=.109, respectively). Stiffness was not different between constructs (P=.103). Polydioxanone and polyglyconate failed by suture breakage and suture pullout. Barbed GTC failed by suture slippage and suture breakage.
  
  
  CONCLUSIONS
  Our results showed that under the conditions of this study, 4-0 monofilament polydioxanone had a greater load at yield and load to failure than similarly sized, barbed copolymer suture in the fascia lata. This finding may help direct suture choice for fascial closure.
authors.affiliation: Department of Clinical Sciences (Companion Animals), College of Veterinary Medicine, University of Liège, Liège, Belgium.
authors.forename: Naomi
authors.initials: N
authors.lastname: Shimizu
authors.affiliation: School of Veterinary Sciences, University of Bristol, Bristol, United Kingdom.
authors.forename: John
authors.initials: J
authors.lastname: Tarlton
authors.affiliation: School of Veterinary Sciences, University of Bristol, Bristol, United Kingdom.
authors.forename: Ed
authors.initials: E
authors.lastname: Friend
authors.affiliation: School of Veterinary Sciences, University of Bristol, Bristol, United Kingdom.
authors.forename: Ivan
authors.initials: I
authors.lastname: Doran
authors.affiliation: School of Veterinary Sciences, University of Bristol, Bristol, United Kingdom.
authors.forename: Kevin
authors.initials: K
authors.lastname: Parsons
mesh_terms: D034861:Abdominal Wall / Q000601:surgery; D000818:Animals; D001696:Biomechanical Phenomena; D002102:Cadaver; D004146:Dioxanes; D004285:Dogs / Q000601:surgery*; D005206:Fascia Lata / Q000601:surgery*; D016687:Polydioxanone; D011108:Polymers; D013536:Suture Techniques / Q000662:veterinary*; D013537:Sutures / Q000662:veterinary*; D013718:Tensile Strength
chemical_list: D004146:Dioxanes; D011108:Polymers; D016687:Polydioxanone; C443643:trimethylene carbonate; C046409:polyglyconate