title: A Retrospective Evaluation of Clinical Profile of Second Primary Head and Neck Cancer.
abstract: BACKGROUND
  Incidence of Second Primary Malignancy (SPM) after successful treatment of primary is increasing and may cause the problem for optimal treatment.
  
  
  OBJECTIVE
  This study was conducted retrospectively to analyse incidence, disease free survival between malignancies, pattern of treatment and outcome.
  
  
  METHODS
  Sixteen out of 22 patients of previously treated cases of head and neck cancer those develop SPM of head and neck region managed over a period of January 2012 to December 2015 in Department of Radiotherapy-II, Pt. BD Sharma PGIMS, Rohtak were analyzed retrospectively. Sixteen patients with unresectable disease were given reirradiation with external beam radiotherapy.
  
  
  RESULTS
  Median age of presentation of first malignancy was 27 years (Ranged 26 -65 years), whereas median age was 60 years for second malignancy (range 45-71 years). All patients were smokers during first malignancy; 87.5% (14/16) had historyof smoking during second malignancy. Oropharynx (50%) was most common site of presentation of primary tumor whereas oral cavity was most common site of presentation in second primary tumor.
  
  
  CONCLUSIONS
  Incidence of Second primary head and neck tumor after successful treatment for primary Head and neck cancer are increasing due to newer treatment strategies, longer survival and follow up. Reirradiation, surgery and or chemotherapy are treatment modalities. However second primary tumor of this region are associated with poor prognosis.
authors.affiliation: Associate Professor, Department of Radiotherapy, Pt BDS PGIMS , Rohtak, Haryana, India .
authors.forename: Paramjeet
authors.initials: P
authors.lastname: Kaur
authors.affiliation: Senior Resident, Department of Radiotherapy, Pt BDS PGIMS , Rohtak, Haryana, India .
authors.forename: Nupur
authors.initials: N
authors.lastname: Bansal
authors.affiliation: Fellow in "Advanced Techniques in Radiotherapy" Health Care Global Enterprises Ltd. , Bangalore, India; HCG Bangalore Institute of Oncology, Bangalore, India .
authors.forename: J Vijaya
authors.initials: JV
authors.lastname: Kumar
authors.affiliation: Medical Officer, Department of Radiotherapy, Pt BDS PGIMS , Rohtak, Haryana, India .
authors.forename: Anil
authors.initials: A
authors.lastname: Khurana
authors.affiliation: Senior Professor, Department of Radiotherapy, Pt BDS PGIMS , Rohtak, Haryana, India .
authors.forename: Ashok
authors.initials: A
authors.lastname: Chauhan
keywords: Concomitant chemoradiation; Locally advanced; Reirradiation