title: Arrangement at the nanoscale: Effect on magnetic particle hyperthermia.
abstract: In this work, we present the arrangement of Fe3O4magnetic nanoparticles into 3D linear chains and its effect on magnetic particle hyperthermia efficiency. The alignment has been performed under a 40 mT magnetic field in an agarose gel matrix. Two different sizes of magnetite nanoparticles, 10 and 40 nm, have been examined, exhibiting room temperature superparamagnetic and ferromagnetic behavior, in terms of DC magnetic field, respectively. The chain formation is experimentally visualized by scanning electron microscopy images. A molecular Dynamics anisotropic diffusion model that outlines the role of intrinsic particle properties and inter-particle distances on dipolar interactions has been used to simulate the chain formation process. The anisotropic character of the aligned samples is also reflected to ferromagnetic resonance and static magnetometry measurements. Compared to the non-aligned samples, magnetically aligned ones present enhanced heating efficiency increasing specific loss power value by a factor of two. Dipolar interactions are responsible for the chain formation of controllable density and thickness inducing shape anisotropy, which in turn enhances magnetic particle hyperthermia efficiency.
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: E
authors.initials: E
authors.lastname: Myrovali
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Maniotis
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Makridis
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Terzopoulou
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: V
authors.initials: V
authors.lastname: Ntomprougkidis
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Simeonidis
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Sakellari
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: O
authors.initials: O
authors.lastname: Kalogirou
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: T
authors.initials: T
authors.lastname: Samaras
authors.affiliation: Faculty of Physics and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, 47048 Duisburg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Salikhov
authors.affiliation: Faculty of Physics and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, 47048 Duisburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Spasova
authors.affiliation: Faculty of Physics and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, 47048 Duisburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Farle
authors.affiliation: Faculty of Physics and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, 47048 Duisburg, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Wiedwald
authors.affiliation: Physics Department, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Angelakeris
mesh_terms: D006358:Hot Temperature; D060328:Magnetic Phenomena; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008962:Models, Theoretical
chemical_list: D058185:Magnetite Nanoparticles