title: Long Noncoding RNAs in Metabolic Syndrome Related Disorders.
abstract: Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA)) that are engaged in basic cellular processes and by regulatory noncoding RNA (short and long noncoding RNA (ncRNA)) that are important for gene expression/transcript stability. In this review, we summarize data concerning the significance of long noncoding RNAs (lncRNAs) in metabolic syndrome related disorders, focusing on adipose tissue and pancreatic islands.
authors.affiliation: Faculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, Poland.
authors.forename: Magdalena
authors.identifier: 0000-0001-9511-1747
authors.initials: M
authors.lastname: Losko
authors.affiliation: Faculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, Poland.
authors.forename: Jerzy
authors.identifier: 0000-0002-3133-3364
authors.initials: J
authors.lastname: Kotlinowski
authors.affiliation: Faculty of Biochemistry, Biophysics and Biotechnology, Department of General Biochemistry, Jagiellonian University, Krakow, Poland.
authors.forename: Jolanta
authors.identifier: 0000-0002-0816-3475
authors.initials: J
authors.lastname: Jura
mesh_terms: D000818:Animals; D006801:Humans; D024821:Metabolic Syndrome / Q000235:genetics* / Q000378:metabolism*; D062085:RNA, Long Noncoding / Q000235:genetics / Q000378:metabolism*; D012335:RNA, Ribosomal / Q000235:genetics / Q000378:metabolism; D012342:RNA, Small Nuclear / Q000235:genetics / Q000378:metabolism; D022661:RNA, Untranslated / Q000235:genetics / Q000378:metabolism
chemical_list: D062085:RNA, Long Noncoding; D012335:RNA, Ribosomal; D012342:RNA, Small Nuclear; D022661:RNA, Untranslated