title: Hemophagocytic Syndrome due to Leishmania Infection Diagnosed with Immunofluorescence Antibody Test.
abstract: Leishmaniasis is a reticuloendothelial system disease that mostly observed before the age of 5. Visceral infection causes long-standing fever, weight loss, weakness, pancytopenia, and hepatosplenomegaly. Leishmania infantum is responsible for visceral leishmaniasis (VL) in Turkey. We present a case of hemophagocytic syndrome due to Leishmania infection diagnosed with an immunofluorescence antibody test (IFAT). Leishmania amastigotes were not observed on bone marrow aspiration. We consider that IFAT is very important for parasite detection in the diagnosis of VL in children, particularly when amastigotes are not obtained on bone marrow aspiration.
authors.affiliation: Pamukkale Üniversitesi Tıp Fakültesi, Çocuk Hematoloji ve Onkoloji Bilim Dalı, Denizli, Türkiye. drhakansarbay@hotmail.com.
authors.forename: Hakan
authors.initials: H
authors.lastname: Sarbay
authors.forename: Yasemin Işık
authors.initials: YI
authors.lastname: Balcı
authors.forename: Selin
authors.initials: S
authors.lastname: Güler
authors.forename: Meral
authors.initials: M
authors.lastname: Türk
authors.forename: Mehmet
authors.initials: M
authors.lastname: Akın
authors.forename: Aziz
authors.initials: A
authors.lastname: Polat
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005334:Fever / Q000209:etiology; D005455:Fluorescent Antibody Technique; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D018314:Leishmania infantum / Q000276:immunology; D007898:Leishmaniasis, Visceral / Q000150:complications / Q000175:diagnosis*; D008297:Male; D013577:Syndrome; D014421:Turkey; D015431:Weight Loss