title: Anti-retroviral therapy's miracle in the treatment of Bowen's disease in a human immunodeficiency virus-positive patient: A rare case report.
abstract: Bowen's disease (BD) is a form of squamous cell carcinomain situoften associated with human papillomavirus. Co-infection with human immunodeficiency virus (HIV) is associated with a greater risk of malignancy. We describe a case of BD in a 52-year-old unmarried HIV-positive male who presented with extensive skin lesions of 1-year duration. Histopathology was suggestive of BD. He had been tried with topical imiquimod cream and cryo-therapy for 6 months. We observed no response for these above therapies. He was started on with anti-retroviral therapy (ART) as his CD4 count was 253 cells/mm3. The entire cutaneous lesions completely disappeared within 6 months of ART, which was an interesting incidence.
authors.affiliation: Department of Skin and STD, V.M.K.V. Medical College and Hospitals, Salem, Tamil Nadu, India.
authors.forename: Kannan
authors.initials: K
authors.lastname: Gopalan
authors.affiliation: Department of Skin and STD, V.M.K.V. Medical College and Hospitals, Salem, Tamil Nadu, India.
authors.forename: Seethalakshmi Ganga
authors.initials: SG
authors.lastname: Vellaisamy
authors.affiliation: Department of Skin and STD, V.M.K.V. Medical College and Hospitals, Salem, Tamil Nadu, India.
authors.forename: Navakumar
authors.initials: N
authors.lastname: Manickam
authors.affiliation: Department of Skin and STD, V.M.K.V. Medical College and Hospitals, Salem, Tamil Nadu, India.
authors.forename: Razil
authors.initials: R
authors.lastname: Ahamed
keywords: Anti-retroviral therapy; Bowen's disease; human Immunodeficiency virus