title: HIV-related shame and health-related quality of life among older, HIV-positive adults.
abstract: This study investigated how HIV-related shame is associated with health-related quality of life (HRQoL) in older people living with HIV (PLHIV). Structural equation modeling tested whether HIV-related shame was associated with three dimensions of HRQoL (physical, emotional, and social well-being) and whether there were significant indirect associations of HIV-related shame with the three HRQoL dimensions via depression and loneliness in a sample of 299 PLHIV ≥50 years old. Results showed that depression and loneliness were key mechanisms, with depression at least partially accounting for the association between HIV-related shame and both emotional and physical well-being, respectively, and loneliness accounting for the association between HIV-related shame and social well-being. HIV-related shame appears to be an important correlate of HRQoL in older PLHIV and may provide a promising leveraging point by which to improve HRQoL in older PLHIV.
authors.affiliation: Department of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, CA, USA. wilson.vincent@ucsf.edu.
authors.forename: Wilson
authors.initials: W
authors.lastname: Vincent
authors.affiliation: School of Public Health, Yale University, New Haven, CT, USA.
authors.forename: Xindi
authors.initials: X
authors.lastname: Fang
authors.affiliation: Department of Psychology, George Washington University, Washington, DC, USA.
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Calabrese
authors.affiliation: College of Public Health, University of Georgia, Athens, GA, USA.
authors.forename: Timothy G
authors.initials: TG
authors.lastname: Heckman
authors.affiliation: Department of Psychology and Neuroscience and Duke Global Health Institute, Duke University, Durham, NC, USA.
authors.forename: Kathleen J
authors.initials: KJ
authors.lastname: Sikkema
authors.affiliation: College of Public Health, University of Georgia, Athens, GA, USA.
authors.forename: Nathan B
authors.initials: NB
authors.lastname: Hansen
mesh_terms: D003863:Depression / Q000150:complications / Q000523:psychology; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000523:psychology*; D006801:Humans; D008132:Loneliness / Q000523:psychology; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D012752:Shame
keywords: Aging; Depression; HIV/AIDS; Loneliness; Quality of life; Shame