title: [Novel therapeutic approaches in inflammatory bowel diseases].
abstract: Increasing knowledge regarding the immunopathogenesis of IBD has led to the development or approval of novel therapeutic agents for the treatment of Crohn's disease or ulcerative colitis. The new substances for example include antibodies against IL-12 / 23, anti-adhesion molecules and antisense oligonucleotides. The increase of therapeutic options will lead to a change of currently used therapeutic algorithms. Biomarkers to ensure a more individualized therapeutic approach are urgently needed to improve an efficient therapy of IBD patients.
authors.forename: Raja
authors.initials: R
authors.lastname: Atreya
authors.forename: Markus Friedrich
authors.initials: MF
authors.lastname: Neurath
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D016903:Drug Monitoring; D019317:Evidence-Based Medicine; D005762:Gastroenterology / Q000639:trends; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents