title: Management of renal failure in end-stage liver disease: A critical appraisal.
abstract: Renal failure is a late consequence of end-stage liver disease (ESLD). Even with liver transplantation, pretransplant renal impairment remains a strong predictor of posttransplant mortality. This review seeks to summarize and critically appraise common therapies used in this setting, including pharmacologic agents, procedures (transjugular intrahepatic portosystemic shunt, renal replacement therapy), and simultaneous liver-kidney transplantation. More experimental extracorporal modalities, eg, albumin dialysis or bioartificial livers, will not be discussed. A brief discussion on the definition and pathophysiologic underpinnings of renal failure in ESLD will be held at the beginning to lay the groundwork for the main section. Liver Transplantation 22 1710-1719 2016 AASLD.
authors.affiliation: Division of Nephrology, Stanford University, Palo Alto, CA.
authors.forename: Xingxing S
authors.initials: XS
authors.lastname: Cheng
authors.affiliation: Division of Nephrology, Stanford University, Palo Alto, CA.
authors.forename: Jane C
authors.initials: JC
authors.lastname: Tan
authors.affiliation: Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, CA.
authors.forename: W Ray
authors.initials: WR
authors.lastname: Kim
mesh_terms: D058625:End Stage Liver Disease / Q000150:complications* / Q000601:surgery; D005919:Glomerular Filtration Rate; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects / Q000379:methods; D016030:Kidney Transplantation / Q000379:methods*; D016031:Liver Transplantation / Q000379:methods*; D010952:Plasma Substitutes / Q000627:therapeutic use; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D051437:Renal Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D017582:Renal Replacement Therapy; D012307:Risk Factors; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D010952:Plasma Substitutes; D014662:Vasoconstrictor Agents