title: Reactions Catalysed by a Binuclear Copper Complex: Relay Aerobic Oxidation of N-Aryl Tetrahydroisoquinolines to Dihydroisoquinolones with a Vitamin B1 Analogue.
abstract: N-Aryl tetrahydroisoquinolines were oxidised to dihydroisoquinolones through the relay catalysis of a binuclear paddle-wheel copper complex and a vitamin B1 analogue with oxygen as oxidant. Mechanistic studies revealed that the copper catalyst oxidises amines to the corresponding iminium salts, which are then oxygenated to lactam products by catalysis of the vitamin B1 analogue.
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
authors.forename: Yuxia
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
authors.forename: Chao
authors.identifier: http://orcid.org/0000-0003-4812-6000
authors.initials: C
authors.lastname: Wang
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
authors.forename: Dong
authors.initials: D
authors.lastname: Xue
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
authors.forename: Miao
authors.initials: M
authors.lastname: Xiao
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
authors.forename: Jiao
authors.initials: J
authors.lastname: Liu
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.
authors.forename: Chaoqun
authors.initials: C
authors.lastname: Li
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, P. R. China.|Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD, UK.
authors.forename: Jianliang
authors.initials: J
authors.lastname: Xiao
mesh_terms: D000577:Amides / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D044005:Tetrahydroisoquinolines / Q000737:chemistry*; D013831:Thiamine / Q000031:analogs & derivatives*
chemical_list: D000577:Amides; D016877:Oxidants; D044005:Tetrahydroisoquinolines; D003300:Copper; D010100:Oxygen; D013831:Thiamine
keywords: amides; copper; homogeneous catalysis; oxidation; relay catalysis