title: Interventional Treatment of Severe Portal Vein Thrombosis after Living-Donor Liver Transplantation.
abstract: Portal vein thrombosis (PVT) is a rare complication of liver transplantation which can lead to graft failure and patient death. Treatment can be difficult, especially in cases of PVT from the intrahepatic portal vein to the proximal jejunal veins. A 55-year-old woman had undergone living-donor liver transplantation with splenectomy for end-stage liver cirrhosis due to hepatitis C with hepatocellular carcinoma. Ten months after transplantation, massive ascites and slight abdominal pain developed, and computed tomography revealed a PVT between the intrahepatic portal vein and the superior mesenteric vein. Repeated interventional radiology procedures were used in combination with thrombolysis, thrombectomy, and metallic stent replacement to obtain favorable portal flow to the graft. Five years after being treated, the patient is well, with favorable portal flow having been confirmed. In conclusion, repeated and assiduous interventional radiological treatment combined with thrombolytic therapy, thrombectomy, and metallic stent replacement could be important for severe PVT.
authors.affiliation: Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School.
authors.forename: Youichi
authors.initials: Y
authors.lastname: Kawano
authors.forename: Satoru
authors.initials: S
authors.lastname: Murata
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Taniai
authors.forename: Masato
authors.initials: M
authors.lastname: Yoshioka
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hirakata
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Mizuguchi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Shimizu
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kanda
authors.forename: Junji
authors.initials: J
authors.lastname: Ueda
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Takada
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yoshida
authors.forename: Koho
authors.initials: K
authors.lastname: Akimaru
authors.forename: Shiro
authors.initials: S
authors.lastname: Onozawa
authors.forename: Shinichirou
authors.initials: S
authors.lastname: Kumita
authors.forename: Eiji
authors.initials: E
authors.lastname: Uchida
mesh_terms: D000792:Angiography; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D019520:Living Donors; D008875:Middle Aged; D011169:Portal Vein / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000628:therapy*