title: A new trick for an old lipid.
abstract: Cholesterol can regulate the Hedgehog signalling pathway by directly binding to a receptor on the cell surface.
authors.affiliation: Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.
authors.forename: Hayley
authors.initials: H
authors.lastname: Sharpe
mesh_terms: D002352:Carrier Proteins; D002462:Cell Membrane; D053823:Hedgehog Proteins; D006801:Humans; D008055:Lipids; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D015398:Signal Transduction
chemical_list: D002352:Carrier Proteins; D053823:Hedgehog Proteins; D008055:Lipids; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled
keywords: G-protein coupled receptor; Hedgehog signaling; biochemistry; cholesterol; developmental biology; human; mouse; stem cells