title: Glucose selective bis-boronic acid click-fluor.
abstract: Four novel bis-boronic acid compounds were synthesised via copper catalysed azide-alkyne cycloaddition (CuAAC) reactions. Glucose selectivity was observed for a particular structural motif. Moreover, a new glucose selective fluorescent sensor was designed and synthesised as a result.
authors.affiliation: School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands, B15 2TT, UK. J.s.fossey@bham.ac.uk.
authors.forename: Wenlei
authors.initials: W
authors.lastname: Zhai
authors.affiliation: X-Ray Crystallography Facility, School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands, UK.
authors.forename: Louise
authors.initials: L
authors.lastname: Male
authors.affiliation: School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands, B15 2TT, UK. J.s.fossey@bham.ac.uk.
authors.forename: John S
authors.identifier: http://orcid.org/0000-0002-2626-5117
authors.initials: JS
authors.lastname: Fossey
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D001665:Binding Sites; D001897:Boronic Acids / Q000737:chemistry* / Q000378:metabolism; D002151:Calorimetry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D018360:Crystallography, X-Ray; D061565:Cycloaddition Reaction; D005456:Fluorescent Dyes / Q000737:chemistry; D005947:Glucose / Q000737:chemistry* / Q000378:metabolism; D008968:Molecular Conformation; D013050:Spectrometry, Fluorescence
chemical_list: D000480:Alkynes; D001386:Azides; D001897:Boronic Acids; D005456:Fluorescent Dyes; D003300:Copper; D005947:Glucose