title: Visualisation studies and glomerular filtration in early diabetic rats.
abstract: The purpose of this mini-review is to show that more modern multi-photon microscopy approaches allow quantitative glomerular filtration experiments. Modern science has now entered a transition period from light microscopy to multi-photon confocal microscopy. Since the late 20th century, multi-photon microscopy has been applied in the study of organ function. In keeping with observations made in renal physiology and other representative studies throughout this transition period, and in the context of advancing microscopy techniques, this review has been presented as a comment on the glomerular filtration barrier, with a focus on the early aetiopathogenesis of diabetes.
authors.affiliation: Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki, Okayama, Japan. Electronic address: hershey@me.kawasaki-m.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakamoto
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000503:physiopathology; D036641:Microscopy, Fluorescence, Multiphoton; D051381:Rats
keywords: Glomerular filtration; In-vivo; Kidney; Microcirculation; Multi-photon microscopy; Visualisation