title: In-Hospital Outcomes and Complications of Coronary Artery Bypass Grafting in the United States Between 2008 and 2012.
abstract: OBJECTIVE
  To investigate the frequency and predictors of in-hospital complications among patients undergoing coronary artery bypass grafting (CABG) in the United States.
  
  
  METHODS
  Retrospective national database analysis SETTINGS: United States hospitals.
  
  
  METHODS
  A weighted sample of 1,910,236 patients undergoing CABG surgery identified from the National (Nationwide) Inpatient Sample from 2008 to 2012.
  
  
  METHODS
  CABG surgery MEASUREMENTS AND MAIN RESULTS: The number of CABG surgeries decreased from 436,275 in 2008 to 339,749 in 2012. The Deyo comorbidity index showed a steady increase from 2008 to 2012. The rate of in-hospital mortality decreased from 2.7% in 2008 to 2.2% in 2012 (p<0.001). The most common in-hospital complication was postoperative hemorrhage (30.4%), followed by cardiac (11.34%) and respiratory complications (2.3%). During the 5-year period, the rates of in-hospital cardiac, respiratory and infectious complications decreased (p<0.001), while the rate of postoperative hemorrhage showed a 35.8% relative increase in 2012 compared to 2008.
  
  
  CONCLUSIONS
  The annual number of CABG surgeries is declining in the United States. While the burden of comorbidities is increasing, the rates of mortality and most in-hospital complications are improving. The increasing rate of postoperative bleeding necessitates the need to develop strategies to improve the risk of bleeding in this patient population.
authors.affiliation: Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ.
authors.forename: Kasra
authors.initials: K
authors.lastname: Moazzami
authors.affiliation: Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ.
authors.forename: Elena
authors.initials: E
authors.lastname: Dolmatova
authors.affiliation: Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ; Division of Cardiology, Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ.
authors.forename: James
authors.initials: J
authors.lastname: Maher
authors.affiliation: Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ; Division of Cardiology, Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ.
authors.forename: Christine
authors.initials: C
authors.lastname: Gerula
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ.
authors.forename: Justin
authors.initials: J
authors.lastname: Sambol
authors.affiliation: Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ; Division of Cardiology, Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ.
authors.forename: Marc
authors.initials: M
authors.lastname: Klapholz
authors.affiliation: Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ; Division of Cardiology, Department of Medicine, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, NJ. Electronic address: ahw22@njms.rutgers.edu.
authors.forename: Alfonso H
authors.initials: AH
authors.lastname: Waller
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity / Q000639:trends; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality / Q000706:statistics & numerical data; D016208:Databases, Factual; D005260:Female; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D019106:Postoperative Hemorrhage / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D055815:Young Adult
keywords: complication; coronary artery bypass grafting; mortality