title: One Coin, No Need to Flip: Shared PET Targets in Cancer and Coronary Artery Disease.
abstract: OBJECTIVE
  The purposes of this article are to review the common biologic features of cancer and coronary artery disease assessed with PET tracers, focusing on those already used in the clinic and those with translational potential, and to discuss the current value and expected contribution of PET in diagnosis, risk stratification, and treatment monitoring.
  
  
  CONCLUSIONS
  PET using a wide variety of radiotracers enhances understanding of pathophysiologic changes shared by cancer and coronary artery disease, helps establish an accurate diagnosis, and aids in prognostic assessment and management decisions. It is likely that with the evolution of therapeutic strategies for blocking the development and progression of both diseases and with the introduction of novel, specific ligands in clinical practice, PET will play an ever stronger role in diagnosis, risk stratification, and monitoring of therapy.
authors.affiliation: 1 Department of Nuclear Medicine, Theagenion Cancer Hospital, Thessaloniki, Greece.
authors.forename: Anna N
authors.initials: AN
authors.lastname: Paschali
authors.affiliation: 2 Nuklearmedizinische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universitaet München, München, Germany.
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Nekolla
authors.affiliation: 3 Department of Histology and Embryology, Athens Medical School, Athens, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Evangelou
authors.affiliation: 4 PET Imaging Centre, St Thomas' Hospital, London, UK.
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Cook
authors.affiliation: 5 PET/CT Department and MicroPET/CT Unit, Center for Experimental Surgery, Clinical and Translational Research, Biomedical Research Foundation Academy of Athens, 4 Soranou Ephessiou St, 115 27 Athens, Greece.
authors.forename: Constantinos D
authors.initials: CD
authors.lastname: Anagnostopoulos
mesh_terms: D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D006801:Humans; D057054:Molecular Imaging / Q000379:methods*; D009369:Neoplasms / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals
keywords: PET; cancer; coronary artery disease; tracers