title: A velocity tracking approach for the data assimilation problem in blood flow simulations.
abstract: Several advances have been made in data assimilation techniques applied to blood flow modeling. Typically, idealized boundary conditions, only verified in straight parts of the vessel, are assumed. We present a general approach, on the basis of a Dirichlet boundary control problem, that may potentially be used in different parts of the arterial system. The relevance of this method appears when computational reconstructions of the 3D domains, prone to be considered sufficiently extended, are either not possible, or desirable, because of computational costs. On the basis of taking a fully unknown velocity profile as the control, the approach uses a discretize then optimize methodology to solve the control problem numerically. The methodology is applied to a realistic 3D geometry representing a brain aneurysm. The results show that this data assimilation approach may be preferable to a pressure control strategy and that it can significantly improve the accuracy associated to typical solutions obtained using idealized velocity profiles.
authors.affiliation: Department of Mathematics and CEMAT, IST, ULisboa, Portugal.
authors.forename: J
authors.identifier: 0000-0001-8979-2136
authors.initials: J
authors.lastname: Tiago
authors.affiliation: ESTBarreiro, Instituto Politécnico de Setúbal, Portugal.
authors.forename: T
authors.initials: T
authors.lastname: Guerra
authors.affiliation: Department of Mathematics and CEMAT, IST, ULisboa, Portugal.
authors.forename: A
authors.initials: A
authors.lastname: Sequeira
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity / Q000502:physiology*; D006439:Hemodynamics; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
keywords: blood flow; boundary control; data assimilation; sequential quadratic programming