title: Spin-labelled diketopiperazines and peptide-peptoid chimera by Ugi-multi-component-reactions.
abstract: For the first time, spin-labelled coumpounds have been obtained by isonitrile-based multi component reactions (IMCRs). The typical IMCR Ugi-protocols offer a simple experimental setup allowing structural variety by which labelled diketopiperazines (DKPs) and peptide-peptoid chimera have been synthesized. The reaction keeps the paramagnetic spin label intact and offers a simple and versatile route to a large variety of new and chemically diverse spin labels.
authors.affiliation: Leibniz-Institute of Plant Biochemistry, Department of Bioorganic Chemistry, Weinberg 3, 06120 Halle, Germany. bernhard.westermann@ipb-halle.de.
authors.forename: Haider N
authors.initials: HN
authors.lastname: Sultani
authors.forename: Haleh H
authors.initials: HH
authors.lastname: Haeri
authors.forename: Dariush
authors.initials: D
authors.lastname: Hinderberger
authors.forename: Bernhard
authors.initials: B
authors.lastname: Westermann
mesh_terms: D054659:Diketopiperazines / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D054659:Diketopiperazines; D010455:Peptides