title: Focused Ultrasound Help Realize High Spatiotemporal Brain Imaging?-A Concept on Acousto-Electrophysiological Neuroimaging.
abstract: We present a concept for integrating focused ultrasound (FUS) with electrophysiological neuroimaging, in order to achieve high spatiotemporal resolution brain imaging. This approach, which we are tentatively calling acousto-electrophysiological neuroimaging, leverages on the spatial focality and noninvasiveness of FUS and may potentially lead to a noninvasive human brain imaging modality with high resolution in both space and time domains. By the use of modulated FUS, spatial selectivity can be accomplished for high-resolution electrophysiological neuroimaging. Frequency shifting in resulting magnetic signals (using modulated FUS) may potentially open the door for a room temperature magnetoencephalography device.
authors.forename: Bin
authors.initials: B
authors.lastname: He
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging*; D004569:Electroencephalography / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D015225:Magnetoencephalography / Q000379:methods; D059906:Neuroimaging / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D014463:Ultrasonography / Q000379:methods*