title: [Tissue regenerative therapies based on regulatory mechanisms underlying bone and cartilage development.]
abstract: Regenerative medicine is an approach that maximizes the natural healing ability by modulating regeneration-inducing signals within appropriate cells in combination with scaffolds. Tissue repair processes and developmental processes largely share common molecular mechanisms. Being inspired by the mechanisms, a large number of studies have been carried out on development of efficient systems for bone and cartilage regeneration. It would be the next step in this field to achieve the stability of regenerated tissues by modulating signals and intracellular molecules that are involved in the maintenance and metabolism of the tissues.
authors.affiliation: Department of Bioengineering, The University of Tokyo Graduate School of Engineering, Japan.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Ohba
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000166:cytology / Q000378:metabolism*; D002356:Cartilage / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D012038:Regeneration; D044968:Regenerative Medicine / Q000379:methods; D023822:Tissue Engineering