title: Differentiation of Constriction and Restriction: Complex Cardiovascular Hemodynamics.
abstract: Differentiation of constrictive pericarditis (CP) from restrictive cardiomyopathy (RCM) is a complex and often challenging process. Because CP is a potentially curable cause of heart failure and therapeutic options for RCM are limited, distinction of these 2 conditions is critical. Although different in regard to etiology, prognosis, and treatment, CP and RCM share a common clinical presentation of predominantly right-sided heart failure, in the absence of significant left ventricular systolic dysfunction or valve disease, due to impaired ventricular diastolic filling. Fundamental to the diagnosis of either condition is a clear understanding of the underlying hemodynamic principles and pathophysiology. We present a contemporary review of the pathophysiology, hemodynamics, diagnostic assessment, and therapeutic approach to patients presenting with CP and RCM.
authors.affiliation: Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address: geske.jeffrey@mayo.edu.
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Geske
authors.affiliation: Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
authors.forename: Nandan S
authors.initials: NS
authors.lastname: Anavekar
authors.affiliation: Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
authors.forename: Rick A
authors.initials: RA
authors.lastname: Nishimura
authors.affiliation: Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
authors.forename: Jae K
authors.initials: JK
authors.lastname: Oh
authors.affiliation: Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
authors.forename: Bernard J
authors.initials: BJ
authors.lastname: Gersh
mesh_terms: D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D010494:Pericarditis, Constrictive / Q000175:diagnosis* / Q000503:physiopathology
keywords: constrictive pericarditis; heart failure; hemodynamics; restrictive cardiomyopathy