title: Remote detection of hyperpolarized129Xe resonances via multiple distant dipolar field interactions with1H.
abstract: A remote detection scheme utilizing the distant dipolar field interaction between two different spin species was proposed by Granwehr et al. [J. Magn. Reson. 176(2), 125 (2005)]. In that sequence1H spins were detected indirectly via their dipolar field interaction with129Xe spins, which served as the sensing spins. Here we propose a modification of the proposed detection scheme that takes advantage of the longer T1relaxation time of xenon to create a long lasting dipolar field with which the fast relaxing1H spins are allowed to interact many times during a single acquisition. This new acquisition scheme improves detection sensitivity, but it also presents some challenges.
authors.affiliation: Department of Applied Physical Sciences, UNC-Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors.forename: Le
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Biomedical Research Imaging Center, UNC-Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Antonacci
authors.affiliation: Biomedical Research Imaging Center, UNC-Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors.forename: Alex
authors.initials: A
authors.lastname: Burant
authors.affiliation: Eshelman School of Pharmacy, UNC-Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors.forename: Karl M
authors.initials: KM
authors.lastname: Koshlap
authors.affiliation: Biomedical Research Imaging Center, UNC-Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors.forename: Rosa Tamara
authors.initials: RT
authors.lastname: Branca