title: Changes at Mean Platelet Volume and Platelet Distribution Width Levels After Septoplasty and Its Correlation With Epworth Sleepness Scale.
abstract: OBJECTIVE
  Nasal septum deviation may affect cardiopulmonary system. Those effects can be determined via blood tests and Epworth sleepness scale (ESS). In this study, it was aimed to measure mean platelet volume (MPV) and platelet distribution width (PDW) in patients with nasal septum deviation and to assess changes at their levels after septoplasty. Furthermore, it was purposed to document the correlation between ESS score and MPV, PDW levels.
  
  
  METHODS
  Eighty-one patients who underwent septoplasty and 50 healthy controls composed the study group. Epworth sleepness scale was performed to all patients preoperatively and patients were divided into 2 groups in terms of ESS scores. Mean platelet volume and PDW levels were measured preoperatively and it was repeated postoperatively.
  
  
  RESULTS
  In Group A (ESS <10), MPV reduced from 8.48 ± 0.38 fl to 8.47 ± 0.36 fl (P >0.05), PDW reduced from 14.56 ± 1.27% to 14.43 ± 1.03% after surgery (P >0.05). On the other hand, in Group B (ESS ≥10), MPV reduced from 9.54 ± 0.68 fl to 8.87 ± 0.44 fl (P <0.001), PDW reduced from 17.15 ± 1.75% to 15.35 ± 1.29% postoperatively (P <0.001).
  
  
  CONCLUSIONS
  Statistically significant improvements at MPV and PDW levels after surgery were noticed only at patients with excessive daytime sleepness whose ESS score was 10 or above. According to this, it would be preferable to operate these patients earlier to protect them from systemic effects.
authors.affiliation: *Department of Otolaryngology †Department of Pulmonary Diseases, Hakkari State Hospital, Hakkari, Turkey.
authors.forename: Murat S
authors.initials: MS
authors.lastname: Sahin
authors.forename: Deniz
authors.initials: D
authors.lastname: Kizilirmak
mesh_terms: D000328:Adult; D000368:Aged; D006970:Disorders of Excessive Somnolence / Q000097:blood* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D015508:Nasal Obstruction / Q000097:blood* / Q000601:surgery*; D009300:Nasal Septum / Q000601:surgery*; D012016:Reference Values; D012225:Rhinoplasty; D013223:Statistics as Topic