title: ERECTA-family receptor kinase genes redundantly prevent premature progression of secondary growth in the Arabidopsis hypocotyl.
abstract: Secondary growth is driven by continuous cell proliferation and differentiation of the cambium that acts as vascular stem cells, producing xylem and phloem to expand vascular tissues laterally. During secondary growth of hypocotyls in Arabidopsis thaliana, the xylem undergoes a drastic phase transition from a parenchyma-producing phase to a fiber-producing phase at the appropriate time. However, it remains to be fully elucidated how progression of secondary growth is properly controlled. We focused on phenotypes of hypocotyl vasculatures caused by double mutation in ERECTA (ER) and ER-LIKE1 (ERL1) receptor-kinase genes to elucidate their roles in secondary growth. ER and ERL1 redundantly suppressed excessive radial growth of the hypocotyl vasculature during secondary growth. ER and ERL1 also prevented premature initiation of the fiber differentiation process mediated by the NAC SECONDARY WALL THICKENING PROMOTING FACTORs in the hypocotyl xylem. Upon floral transition, the hypocotyl xylem gained a competency to respond to GA in a BREVIPEDICELLUS-dependent manner, which was a prerequisite for fiber differentiation. However, even after the floral transition, ER and ERL1 prevented precocious initiation of the GA-mediated fiber formation. Collectively, our findings reveal that ER and ERL1 redundantly prevent premature progression of sequential events in secondary growth.
authors.affiliation: Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.|Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8602, Japan.
authors.forename: Shuka
authors.initials: S
authors.lastname: Ikematsu
authors.affiliation: Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, 630-0192, Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Tasaka
authors.affiliation: Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.|Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8602, Japan.|Department of Biology, University of Washington, Seattle, WA, 98195, USA.|Howard Hughes Medical Institute, University of Washington, Seattle, WA, 98195, USA.
authors.forename: Keiko U
authors.initials: KU
authors.lastname: Torii
authors.affiliation: Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.|Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8602, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Uchida
mesh_terms: D017360:Arabidopsis / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics* / Q000254:growth & development; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects; D035264:Flowers / Q000187:drug effects / Q000502:physiology; D017343:Genes, Plant; D018525:Germination / Q000187:drug effects; D005875:Gibberellins / Q000494:pharmacology; D018546:Hypocotyl / Q000187:drug effects / Q000254:growth & development*; D005810:Multigene Family; D017346:Protein Serine-Threonine Kinases / Q000235:genetics* / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000235:genetics* / Q000378:metabolism; D052584:Xylem / Q000166:cytology / Q000187:drug effects / Q000254:growth & development
chemical_list: D029681:Arabidopsis Proteins; D005875:Gibberellins; D011956:Receptors, Cell Surface; C457763:ER protein, Arabidopsis; C502168:ERL1 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases
keywords: 
  
  BREVIPEDICELLUS
  
  ; 
  Arabidopsis thaliana
  ; ERECTA family; GA; fiber; floral transition; secondary growth