title: Blood Derived Induced Pluripotent Stem Cells (iPSCs): Benefits, Challenges and the Road Ahead.
abstract: Since the creation of induced Pluripotent Stem Cells (iPSCs) ten years ago, hundreds of publications have demonstrated their considerable impact on disease modeling and therapy. In this commentary, we will summarize key milestones, benefits and challenges in the iPSC field. Furthermore, we will highlight blood as an effective and easily accessible source for patient-specific iPSCs derivation in the context of work done in our laboratory and others.
authors.affiliation: John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, USA.
authors.forename: Jimmy
authors.initials: J
authors.lastname: El Hokayem
authors.affiliation: John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, USA.|Department of Neurology, University of Miami Miller School of Medicine, Miami, USA.
authors.forename: Holly N
authors.initials: HN
authors.lastname: Cukier
authors.affiliation: John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, USA.|John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, USA.
authors.forename: Derek M
authors.initials: DM
authors.lastname: Dykxhoorn