title: CHOROIDAL CHANGES ASSOCIATED WITH SEROUS MACULAR DETACHMENT IN EYES WITH STAPHYLOMA, DOME-SHAPED MACULA OR TILTED DISK SYNDROME.
abstract: OBJECTIVE
  To study the relationship of choroidal abnormalities with serous retinal detachment (SRD) in eyes with staphyloma, dome-shaped macula, or tilted disk syndrome.
  
  
  METHODS
  Group 1, 28 eyes of 20 patients with staphyloma/dome-shaped macula/tilted disk syndrome associated with SRD was compared with Group 2, 30 eyes of 20 patients, with staphyloma/dome-shaped macula/tilted disk syndrome but without SRD. Radial and en-face optical coherence tomography and choroidal analysis were performed.
  
  
  RESULTS
  Group 1 had a thicker mean subfoveal choroidal thickness (161 μm vs. 92 μm, P < 0.05) and a greater variation in choroidal thickness (112 μm vs. 76 μm, P > 0.05) compared with eyes of Group 2. Focal abrupt changes in choroidal thickness were more commonly seen in Group 1 versus eyes in Group 2 (90% vs. 30%, P < 0.05) and this area of abrupt change was located within or at the edge of the SRD in 64% of eyes. Large choroidal vessels (pachyvessels) (82% located within the area of SRD) were always associated with the presence of SRD.
  
  
  CONCLUSIONS
  An abrupt transition in choroidal thickness may be involved in the pathogenesis of SRD. In some cases, a radial scan pattern may better demonstrate mild SRD, choroidal contours and the focal choroidal variations than horizontal or vertical raster scan patterns.
authors.affiliation: *Vitreous Retina Macula Consultants of New York, New York, New York; †LuEsther T Mertz Retinal Research Center, Manhattan, Eye, Ear and Throat Hospital, New York, New York; ‡Singapore National Eye Center, Singapore Eye Research Institute, Singapore, Singapore; §The Rotterdam Eye Hospital, Rotterdam, the Netherlands; ¶Truhlsen Eye Institute, University of Nebraska, Omaha, Nebraska; **Moorfields Eye Hospital, London, United Kingdom; ††Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; ‡‡Stein Eye Institute, University of California, Los Angeles, California; and §§Greater Los Angeles VA Healthcare Center, Los Angeles, California.
authors.forename: Anna C S
authors.initials: ACS
authors.lastname: Tan
authors.forename: Suzanne
authors.initials: S
authors.lastname: Yzer
authors.forename: K Bailey
authors.initials: KB
authors.lastname: Freund
authors.forename: Kunal K
authors.initials: KK
authors.lastname: Dansingani
authors.forename: Nopasak
authors.initials: N
authors.lastname: Phasukkijwatana
authors.forename: David
authors.initials: D
authors.lastname: Sarraf
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000473:pathology*; D015862:Choroid Diseases / Q000175:diagnosis* / Q000209:etiology; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000150:complications / Q000175:diagnosis*; D012163:Retinal Detachment / Q000150:complications / Q000473:pathology*; D012189:Retrospective Studies; D015422:Scleral Diseases / Q000150:complications / Q000175:diagnosis*; D013577:Syndrome; D041623:Tomography, Optical Coherence / Q000379:methods; D014792:Visual Acuity; D055815:Young Adult