title: [Mucoviscidosis, a challenging medical problem].
abstract: The authors present the currently available data on mucoviscidosis (cystic fibrosis) based on their original experience and the review of the relevant literature. Special attention is given to the pathogenetic mechanisms underlying the development of this condition, its diagnostics, and methods of treatment as exemplified by the clinical case of cystic fibrosis in an adult patient.
authors.affiliation: Dagestan State Medical Academy, Russian Ministry of Health, Makhachkala, Russia, 367000.
authors.forename: E M
authors.initials: EM
authors.lastname: Esedov
authors.affiliation: Dagestan State Medical Academy, Russian Ministry of Health, Makhachkala, Russia, 367000.
authors.forename: G A
authors.initials: GA
authors.lastname: Gadzhimirzaev
authors.affiliation: Dagestan State Medical Academy, Russian Ministry of Health, Makhachkala, Russia, 367000.
authors.forename: F D
authors.initials: FD
authors.lastname: Akhmedova
authors.affiliation: Dagestan State Medical Academy, Russian Ministry of Health, Makhachkala, Russia, 367000.
authors.forename: V R
authors.initials: VR
authors.lastname: Muradova
authors.affiliation: Dagestan State Medical Academy, Russian Ministry of Health, Makhachkala, Russia, 367000.
authors.forename: R G
authors.initials: RG
authors.lastname: Gadzhimirzaeva
authors.affiliation: Dagestan State Medical Academy, Russian Ministry of Health, Makhachkala, Russia, 367000.
authors.forename: R A
authors.initials: RA
authors.lastname: Medzhidova
authors.affiliation: Dagestan State Medical Academy, Russian Ministry of Health, Makhachkala, Russia, 367000.
authors.forename: A S
authors.initials: AS
authors.lastname: Abasova
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001999:Bronchoscopy / Q000379:methods; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D019468:Disease Management; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D009154:Mutation; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000302:isolation & purification; D019141:Respiratory System Agents / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; C505032:CFTR protein, human; D019141:Respiratory System Agents; D019005:Cystic Fibrosis Transmembrane Conductance Regulator