title: A Single-Center Experience With Isolated Limb Infusion: An Interventional Oncology Opportunity.
abstract: OBJECTIVE
  This retrospective review details our experience with isolated limb infusion for the treatment of melanoma, squamous cell carcinoma, and sarcoma in-transit metastases performed entirely in the interventional radiology suite. Eleven patients were treated over a 3-year period. Treatment response was assessed clinically and with PET/CT.
  
  
  CONCLUSIONS
  Eight patients had either complete or partial response, giving an overall response rate of 72%. Isolated limb infusion can efficiently be performed entirely in the interventional radiology suite.
authors.affiliation: 1 Department of Radiology, University of Nebraska Medical Center, 98105 Nebraska Medical Center, Omaha, NE 68198-1045.
authors.forename: Adam
authors.initials: A
authors.lastname: DeFoe
authors.affiliation: 1 Department of Radiology, University of Nebraska Medical Center, 98105 Nebraska Medical Center, Omaha, NE 68198-1045.
authors.forename: Andrew
authors.initials: A
authors.lastname: Heckman
authors.affiliation: 1 Department of Radiology, University of Nebraska Medical Center, 98105 Nebraska Medical Center, Omaha, NE 68198-1045.
authors.forename: Dick
authors.initials: D
authors.lastname: Slater
authors.affiliation: 2 Section of General Surgery, Surgical Oncology, University of Nebraska Medical Center, Omaha, NE.
authors.forename: Edibaldo
authors.initials: E
authors.lastname: Silva-Lopez
authors.affiliation: 2 Section of General Surgery, Surgical Oncology, University of Nebraska Medical Center, Omaha, NE.
authors.forename: Jason
authors.initials: J
authors.lastname: Foster
authors.affiliation: 1 Department of Radiology, University of Nebraska Medical Center, 98105 Nebraska Medical Center, Omaha, NE 68198-1045.
authors.forename: Thom
authors.initials: T
authors.lastname: Bowden
authors.affiliation: 1 Department of Radiology, University of Nebraska Medical Center, 98105 Nebraska Medical Center, Omaha, NE 68198-1045.
authors.forename: Christopher
authors.initials: C
authors.lastname: Vargo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D008875:Middle Aged; D015641:Radiography, Interventional / Q000379:methods*; D012189:Retrospective Studies; D012509:Sarcoma / Q000000981:diagnostic imaging*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents
keywords: interventional oncology; isolated limb infusion