title: The Angiotensin-Converting-Enzyme-Induced Angioedema.
abstract: The bradykinin B2 receptor antagonist icatibant is effective in angiotensin-converting enzyme inhibitor-induced angioedema. The drug is not approved officially for this indication and has to be administered in an emergency situation off-label. Corticosteroids or antihistamines do not seem to work in this condition. The effectiveness of C1-esterase-inhibitor in angiotensin-converting enzyme-induced angioedema must be verified in a double-blind study.
authors.affiliation: Clinic of Otorhinolaryngology, Klinikum rechts der Isar, Technische Universität München, Ismaninger St 22, 81675 Munich, Germany. Electronic address: m.bas.hno@gmail.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Bas
mesh_terms: D000799:Angioedema / Q000175:diagnosis* / Q000188:drug therapy; D001920:Bradykinin / Q000031:analogs & derivatives / Q000627:therapeutic use; D065094:Bradykinin B2 Receptor Antagonists / Q000627:therapeutic use; D003937:Diagnosis, Differential; D064420:Drug-Related Side Effects and Adverse Reactions / Q000175:diagnosis* / Q000188:drug therapy; D004632:Emergency Medical Services; D004825:Epiglottis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D056687:Off-Label Use; D012083:Renin / Q000009:adverse effects; D014059:Tongue / Q000276:immunology / Q000473:pathology*; D014581:Urticaria / Q000175:diagnosis*
chemical_list: D065094:Bradykinin B2 Receptor Antagonists; C065679:icatibant; D012083:Renin; D001920:Bradykinin
keywords: ACE inhibitor; Angioedema; Bradykinin; Bradykinin receptors