title: A multicenter study on anaphylaxis caused by peanut, tree nuts, and seeds in children and adolescents.
abstract: Peanut (PN) and tree nuts (TNs) are common causes of anaphylaxis in Western countries, but no information is available in Korea. To feature clinical characteristics of anaphylaxis caused by PN, TNs, and seeds, a retrospective medical record review was performed in 14 university hospitals in Korea (2009-2013). One hundred and twenty-six cases were identified, with the mean age of 4.9 years. PN, walnut (WN), and pine nut accounted for 32.5%, 41.3%, and 7.1%, respectively. The median values of specific IgE (sIgE) to PN, WN, and pine nut were 10.50, 8.74, and 4.61 kUA/l, respectively. Among 50 cases managed in the emergency department, 52.0% were treated with epinephrine, 66.0% with steroid, 94.0% with antihistamines, 36.0% with oxygen, and 48.0% with bronchodilator. In conclusion, WN, PN, and pine nut were the three most common triggers of anaphylaxis in Korean children, and anaphylaxis could occur at remarkably low levels of sIgE.
authors.affiliation: Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
authors.forename: K
authors.initials: K
authors.lastname: Jeong
authors.affiliation: Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
authors.forename: S-Y
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: K
authors.initials: K
authors.lastname: Ahn
authors.affiliation: Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: J
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
authors.forename: H-R
authors.initials: HR
authors.lastname: Lee
authors.affiliation: Department of Pediatrics, Seoul National University Hospital, Seoul, Korea.
authors.forename: D I
authors.initials: DI
authors.lastname: Suh
authors.affiliation: Department of Pediatrics, Soonchunhyang University Hospital, Seoul, Korea.
authors.forename: B-Y
authors.initials: BY
authors.lastname: Pyun
authors.affiliation: Department of Pediatrics, Soonchunhyang University Hospital, Seoul, Korea.
authors.forename: T K
authors.initials: TK
authors.lastname: Min
authors.affiliation: Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: J-W
authors.initials: JW
authors.lastname: Kwon
authors.affiliation: Department of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: K-E
authors.initials: KE
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: K W
authors.initials: KW
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: M H
authors.initials: MH
authors.lastname: Sohn
authors.affiliation: Department of Pediatrics, Severance Hospital, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Y H
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Inje University Ilsan Paik Hospital, Goyang, Korea.
authors.forename: T W
authors.initials: TW
authors.lastname: Song
authors.affiliation: Department of Pediatrics, Korea University College of Medicine, Ansan, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Kwon
authors.affiliation: Department of Pediatrics, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.
authors.forename: Y H
authors.initials: YH
authors.lastname: Jeon
authors.affiliation: Department of Pediatrics, Pusan National University Children's Hospital, Yangsan, Korea.
authors.forename: H Y
authors.initials: HY
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Inha University Hospital, Incheon, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Eulji Hospital, Eulji University School of Medicine, Seoul, Korea.
authors.forename: Y M
authors.initials: YM
authors.lastname: Ahn
authors.affiliation: Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
authors.forename: S
authors.initials: S
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000485:Allergens / Q000276:immunology; D000707:Anaphylaxis / Q000453:epidemiology* / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D007223:Infant; D008297:Male; D000074924:Nut and Peanut Hypersensitivity / Q000453:epidemiology* / Q000276:immunology; D012639:Seeds / Q000009:adverse effects*
chemical_list: D000485:Allergens; D007073:Immunoglobulin E
keywords: Korean children; anaphylaxis; peanut; seeds; tree nuts