title: Management of Trauma-Induced Coagulopathy with Thrombelastography.
abstract: Viscoelastic assays, such as thrombelastography (TEG) and rotational thrombelastometry (ROTEM), have emerged as point-of-care tools that can guide the hemostatic resuscitation of bleeding injured patients. This article describes the role of TEG in contemporary trauma care by explaining this assay's methodology, clinical applications, and result interpretation through description of supporting studies to provide the reader with an evidence-based user's guide. Although TEG and ROTEM are assays based on the same viscoelastic principle, this article is focused on data supporting the use of TEG in trauma, because it is available in trauma centers in North America; ROTEM is mostly available in Europe.
authors.affiliation: Department of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Gonzalez
authors.affiliation: Department of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA; Department of Surgery, Denver Health Medical Center, 77 Bannock Street, Denver, CO 80204, USA; Editorial office, Journal of Trauma and Acute Care Surgery, 655 Broadway, Suite 365, Denver, CO 80203, USA. Electronic address: ernest.moore@dhha.org.
authors.forename: Ernest E
authors.initials: EE
authors.lastname: Moore
authors.affiliation: Department of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA.
authors.forename: Hunter B
authors.initials: HB
authors.lastname: Moore
mesh_terms: D001778:Blood Coagulation Disorders / Q000209:etiology* / Q000628:therapy*; D005060:Europe; D006801:Humans; D009656:North America; D017410:Practice Guidelines as Topic; D013916:Thrombelastography / Q000592:standards*; D014947:Wounds and Injuries / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*
keywords: Coagulopathy; Fibrinolysis; Resuscitation; TEG; Thrombelastography; Transfusion