title: Quality assessment of Traditional Chinese Medicine using HPLC-PAD combined with Tchebichef image moments.
abstract: Traditional Chinese medicines have gotten growing attention and the product quality also became uneven. In this paper, Tchebichef image moments coupled with high performance liquid chromatography with photodiode array detector were proposed to the similarity analysis of the fourteen batches of Pudilan Xiaoyan tablets (Chinese medicine complex), which were based on the grayscale images of three dimensional (3D) fingerprint spectra. Hierarchical cluster analysis was used for displaying the classification results. As a comparison, traditional principal component analysis (PCA) method based on the chromatograms under single-fixed wavelength was carried out on the same samples. The analytical results indicated that the proposed approach could provide more accurate and reasonable results owing to its powerful invariant and multi-resolution capability of image moments.
authors.affiliation: College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
authors.forename: Xue
authors.initials: X
authors.lastname: Wang
authors.affiliation: College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
authors.forename: Bao Qiong
authors.initials: BQ
authors.lastname: Li
authors.affiliation: College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
authors.forename: Min Li
authors.initials: ML
authors.lastname: Xu
authors.affiliation: College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
authors.forename: Jin Jin
authors.initials: JJ
authors.lastname: Liu
authors.affiliation: College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China. Electronic address: zhaihl@163.com.
authors.forename: Hong Lin
authors.initials: HL
authors.lastname: Zhai
mesh_terms: D000465:Algorithms; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D016000:Cluster Analysis; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D025341:Principal Component Analysis; D011786:Quality Control; D013607:Tablets
chemical_list: D004365:Drugs, Chinese Herbal; D013607:Tablets
keywords: Grayscale image; Principal component analysis; Similarity analysis; Tchebichef moment; Traditional Chinese medicines