title: [Low flux dialysate daily home hemodialysis: A result for the 62 first French and Belgian patients].
abstract: Since 2011, a new device is available for low flux dialysate quotidian home hemodialysis in France and Belgium. This study aims to evaluate the characteristics and dialysis prescriptions for Nx Stage System One™ users. We retrospectively included patients trained between 2011 and 2013 in France and Belgium. We collected data concerning their clinical features, their dialysis prescriptions, their laboratory parameters until 6 months of dialysis and, reason for dropping in case of cessation. Sixty-two patients from 31 centers, aged 48±18 years old, with a sex ratio 46/16 (M/F) are included with a median Charlson comorbidity index of 1 [0-3]. Of these patients, 71% are anuric and have been on dialysis for a mean time of 136.6±125 months. Previously, most of them had been taken care of in satellite units of dialysis (45%) and 14% are incident patients. In total, A total of 60% have an arterio-veinous fistula (AVF), with 18 patients using the Buttonhole system and 2 patients have a tunneled catheter. Median time for training was 26.5 days (17-45). Among the patients, 69% are dialyzed 6 days a week, during a mean time of 142.5±20 minutes with a volume of 20.9±3 liters of dialysate and without anticoagulant (63%). Predialytic levels of hemoglobin, creatinin, urea, phosphorus and β2microglobulin remain stable. On the contrary, there is a significant improvement of albumin and bicarbonate levels. Technique survival was 75% at 1 year, and major reason for cessation was kidney transplant. It seems that this device fits for young patients, with few comorbidities and a long past in renal chronic failure. These results suggest that dialysis adequacy is acceptable despite low dialysate volumes but need confirmation with a longer follow up and a larger cohort.
authors.affiliation: Service de néphrologie dialyse transplantation, CHU de Caen, avenue de la Côte-De-Nacre, 14000 Caen, France.
authors.forename: Anaïs
authors.initials: A
authors.lastname: Benabed
authors.affiliation: Service de néphrologie dialyse transplantation, CHU de Caen, avenue de la Côte-De-Nacre, 14000 Caen, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Henri
authors.affiliation: Service de néphrologie dialyse transplantation, CHU de Caen, avenue de la Côte-De-Nacre, 14000 Caen, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Lobbedez
authors.affiliation: Cliniques universitaire Saint-Luc, 10, avenue Hippocrate, 1200 Bruxelles, Belgique.
authors.forename: Eric
authors.initials: E
authors.lastname: Goffin
authors.affiliation: Service de néphrologie urologie dialyse, centre hospitalier Yves-le-Foll, 10, rue Marcel-Proust, 22000 Saint-Brieuc, France.
authors.forename: Simona
authors.initials: S
authors.lastname: Baluta
authors.affiliation: Service de néphrologie dialyse, centre hospitalier d'Arras, 3, boulevard Georges-Besnier, 62022 Arras, France.
authors.forename: Abdelkader
authors.initials: A
authors.lastname: Benziane
authors.affiliation: Service de néphrologie, centre hospitalier de Perpignan, 20, avenue du Languedoc, BP4052, 66046 Perpignan, France.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Rachi
authors.affiliation: Service de néphrologie, centre hospitalier de Hyères, avenue du Maréchal-Juin, 83400 Hyères, France.
authors.forename: Johan W
authors.initials: JW
authors.lastname: van der Pijl
authors.affiliation: Service de néphrologie dialyse transplantation, CHU de Caen, avenue de la Côte-De-Nacre, 14000 Caen, France.
authors.forename: Clémence
authors.initials: C
authors.lastname: Bechade
authors.affiliation: Service de néphrologie dialyse transplantation, CHU de Caen, avenue de la Côte-De-Nacre, 14000 Caen, France. Electronic address: ficheux-m@chu-caen.fr.
authors.forename: Maxence
authors.initials: M
authors.lastname: Ficheux
mesh_terms: D001530:Belgium; D001639:Bicarbonates / Q000097:blood; D015897:Comorbidity; D015314:Dialysis Solutions / Q000008:administration & dosage*; D005260:Female; D005602:France; D006437:Hemodialysis, Home / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012709:Serum Albumin / Q000032:analysis
chemical_list: D001639:Bicarbonates; D015314:Dialysis Solutions; D012709:Serum Albumin
keywords: Bas débit de dialysat; Home; Hémodialyse quotidienne; Low flux dialysate; Quotidian hemodialysis; Soins à domicile