title: Insulin-induced autoimmune syndrome: A case report.
abstract: Insulin autoimmune syndrome (IAS) is a disease characterized by hyperinsulinemic hypoglycemia associated with autoantibodies against endogenous insulin. A 56-year-old man was admitted to Ningbo First Hospital for the treatment of spontaneous hypoglycemia. He was found to have elevated fasting insulin level (>1,000 mIU/l) and presence of insulin autoantibodies, and after appropriate workup, was diagnosed with IAS. After treating with prednisone for 2 months, his insulin level started decreasing. In patients with repeated hypoglycemia, IAS should be considered in the differential diagnosis. Prednisone may be effective for the treatment of hypoglycemia in patients with IAS.
authors.affiliation: Department of Endocrinology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang 315000, P.R. China.
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Chu
authors.affiliation: School of Medicine, Ningbo University, Ningbo, Zhejiang 315000, P.R. China.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Zheng
authors.affiliation: Department of Endocrinology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang 315000, P.R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Lu
authors.affiliation: School of Medicine, Ningbo University, Ningbo, Zhejiang 315000, P.R. China.
authors.forename: Jin-Yan
authors.initials: JY
authors.lastname: Zhong
authors.affiliation: Department of Endocrinology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang 315000, P.R. China.
authors.forename: Jia-Lin
authors.initials: JL
authors.lastname: Li
authors.affiliation: Department of Endocrinology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang 315000, P.R. China.
authors.forename: Miao
authors.initials: M
authors.lastname: Xu
authors.affiliation: Department of Endocrinology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang 315000, P.R. China.
authors.forename: Fang
authors.initials: F
authors.lastname: Lin
keywords: continuous glucose monitoring system; insulin autoantibodies; insulin autoimmune syndrome