title: Interest of Using Ropivacaine for Outpatient Laparoscopic Cholecystectomy: Prospective Randomized Trial.
abstract: The objective of this study was to evaluate the interest of using ropivacaine for outpatient laparoscopic cholecystectomy. The use of local anesthesia by instillation and infiltration could reduce pain and increase the number of outpatient cholecystectomies.
  
  
  
  A one-center randomized prospective clinical trial compared the use of ropivacaine during outpatient laparoscopic cholecystectomy to the control group of outpatients for laparoscopic cholecystectomy between April 2014 and May 2015. One hundred twenty-four were eligible, and 100 patients were randomized. Patients with outpatient cholecystectomy were randomized into 2 groups: ropivacaine group (Rop group) and control group (control group). We performed a ropivacaine intraperitoneal instillation and wound infiltration for the ropivacaine group at the end of the procedure. The primary observation was authorization for home discharge. The patient was evaluated by the surgeon using the Chung score. Secondary observations included postoperative pain at 2 h post-surgery, at 6 h post-surgery and the day following surgery.
  
  
  
  Ninety-eight were able to leave on the evening of surgery. At 6 h post-surgery, the Chung score was identical for both groups (p = 0.73). At 2 and 6 h post-surgery and the day following surgery, there was no significant difference in pain levels (p = 0.63; p = 0.61; p = 0.98). Analgesic consumption was no significant difference in the groups.
  
  
  
  The use of ropivacaine does not increase the rate of home discharge and does not change the postoperative pain of outpatient cholecystectomy.
authors.affiliation: Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France. emeric.abet@chd-vendee.fr.
authors.forename: Emeric
authors.initials: E
authors.lastname: Abet
authors.affiliation: Anesthesiology Service, Vendée Hospital Center, 85000, La Roche Sur Yon, France.
authors.forename: François
authors.initials: F
authors.lastname: Orion
authors.affiliation: Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Denimal
authors.affiliation: Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France.
authors.forename: Anne-Géraldine
authors.initials: AG
authors.lastname: Brau-Weber
authors.affiliation: Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France.
authors.forename: Benoît
authors.initials: B
authors.lastname: de Kerviler
authors.affiliation: Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France.
authors.forename: Marc-Henri
authors.initials: MH
authors.lastname: Jean
authors.affiliation: Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Boulanger
authors.affiliation: Clinical Research Department, Vendée Hospital Center, 85000, La Roche Sur Yon, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Dimet
authors.affiliation: Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Comy
mesh_terms: D000556:Ambulatory Surgical Procedures; D000577:Amides / Q000627:therapeutic use*; D000779:Anesthetics, Local / Q000627:therapeutic use*; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies; D000077212:Ropivacaine
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine