title: An Unusual Evolution of Krukenberg Tumour: A Case Report.
abstract: Krukenberg tumours are rare metastatic tumours of the ovaries characterized by the presence of mucin-producing neoplastic Signet Ring Cell Carcinoma (SRCC). At first glance, this tumour may be confused with a primary ovarian tumour. Surgery and chemotherapy combination have led to improvement in prognosis, but it still remains severe. We report the case of a 60-year-old woman with a Krukenberg tumour rising from a low differentiated gastric adenocarcinoma. The patient was clinically stable for 26 months after surgery until she experienced a prompt decline and died of cerebral haemorrhage within two weeks. The aim of this article was to give an overview of the Krukenberg tumour starting from our case report and comparing it with clinicopathological characteristics of this pathology derived from a review of recent literature.
authors.affiliation: Professor, Department of Surgical, Medical, Molecular Pathology and of the Critical Area, Chair of Pediatric Surgery, University of Pisa , Italy .
authors.forename: Claudio
authors.initials: C
authors.lastname: Spinelli
authors.affiliation: Assistant Professor, Department of Surgical, Medical, Molecular Pathology and of the Critical Area, University of Pisa , Italy .
authors.forename: Concetta
authors.initials: C
authors.lastname: Liloia
authors.affiliation: Assistant Professor, Department of Surgical, Medical, Molecular Pathology and of the Critical Area, University of Pisa , Italy .
authors.forename: Jessica
authors.initials: J
authors.lastname: Piscioneri
authors.affiliation: Assistant Professor, Department of Laboratory Medicine and Integrated Diagnostics, Section of Experimental Pathology, University of Pisa , Italy .
authors.forename: Clara
authors.initials: C
authors.lastname: Ugolini
authors.affiliation: Assistant Professor, Department of Surgical, Medical, Molecular Pathology and of the Critical Area, University of Pisa , Italy .
authors.forename: Silvia
authors.initials: S
authors.lastname: Strambi
keywords: Gastric cancer; Mucinous tumours; Ovarian cancer; Signet ring cell carcinoma