title: Determination and Evaluation of Metallothionein and Metals in Mugil cephalus (Mullet) from Pontal Bay, Brazil.
abstract: To assess environmental contamination, studies have been increasingly carried out using biomarkers to diagnose the effects of toxic metal exposure, such as metallothionein (MT). In this context, the aims of the present study were to determine Cd, Cu, Ni and Pb concentrations, by ICP-MS, in liver samples from Mugil cephalus from the municipality of Ilhéus, located in North-Southeastern Brazil, in the state of Bahia, which has been increasingly suffering from anthropogenic pressure, and to quantify total MT in liver and gills. Among essential metals, copper (199.2 μg g-1) presented concentrations approximately 7 times higher than allowed by the World Health Organization (30 μg g-1). Liver samples showed higher concentrations than gills. Metallothionein concentrations indicate differential contamination along the study area. The first sampling showed higher induction of MT synthesis overall. Differences between liver and gill MT concentration trends were relatively minor, which may indicate the adequacy of analyzing gills in an environmental monitoring context.
authors.affiliation: Departamento de Química e Exatas, Universidade Estadual do Sudoeste da Bahia, Campus universitário de Jequié-BA, Avenida José Moreira Sobrinho, 677-Jequiezinho, Jequié, Bahia, 45206-190, Brazil.|Instituto de Química, Universidade Federal da Bahia, Campus Universitário de Ondina, Salvador, Bahia, 40170-290, Brazil.
authors.forename: Clissiane Soares Viana
authors.initials: CS
authors.lastname: Pacheco
authors.affiliation: Departamento de Química e Exatas, Universidade Estadual do Sudoeste da Bahia, Campus universitário de Jequié-BA, Avenida José Moreira Sobrinho, 677-Jequiezinho, Jequié, Bahia, 45206-190, Brazil. erikgps@gmail.com.|Departamento de Ciências Exatas e Tecnológicas, Universidade Estadual de Santa Cruz, Campus Soane Nazaré de Andrade, Km 16 BR-415, Ilhéus, Bahia, 45662-900, Brazil. erikgps@gmail.com.
authors.forename: Erik Galvão Paranhos
authors.identifier: http://orcid.org/0000-0002-8027-7258
authors.initials: EG
authors.lastname: da Silva
authors.affiliation: Centro de Estudos da Saúde do Trabalhador e Ecologia Humana (CESTEH), ENSP, FIOCRUZ, Rua Leopoldo Bulhões, 1480, Rio de Janeiro, 21041-210, Brazil.
authors.forename: Rachel Ann
authors.initials: RA
authors.lastname: Hauser-Davis
authors.affiliation: Centro de Ciências Exatas e Tecnológicas, Universidade Federal do Recôncavo da Bahia, Campus Universitario de Cruz das Almas, Cruz das Almas, Bahia, 44380-000, Brazil.
authors.forename: Fábio
authors.initials: F
authors.lastname: Dias
authors.affiliation: Departamento de Ciências Exatas e Tecnológicas, Universidade Estadual de Santa Cruz, Campus Soane Nazaré de Andrade, Km 16 BR-415, Ilhéus, Bahia, 45662-900, Brazil.
authors.forename: Fábio Alan Carqueija
authors.initials: FA
authors.lastname: Amorim
authors.affiliation: Departamento de Ciências Exatas e Tecnológicas, Universidade Estadual de Santa Cruz, Campus Soane Nazaré de Andrade, Km 16 BR-415, Ilhéus, Bahia, 45662-900, Brazil.
authors.forename: Raildo Mota
authors.initials: RM
authors.lastname: de Jesus
authors.affiliation: Departamento de Química e Exatas, Universidade Estadual do Sudoeste da Bahia, Campus universitário de Jequié-BA, Avenida José Moreira Sobrinho, 677-Jequiezinho, Jequié, Bahia, 45206-190, Brazil.
authors.forename: Cleber Galvão
authors.initials: CG
authors.lastname: Novaes
authors.affiliation: Instituto de Química, Universidade Federal da Bahia, Campus Universitário de Ondina, Salvador, Bahia, 40170-290, Brazil.
authors.forename: Ana Maria Pinto
authors.initials: AM
authors.lastname: Dos Santos
authors.affiliation: Departamento de Química, Pontifícia Universidade Católica - Rio de Janeiro, Rua Marquês de São Vicente, 225, Gávea, Rio de Janeiro, 22453-900, Brazil.
authors.forename: Tatiana Dillenburg
authors.initials: TD
authors.lastname: Saint'Pierre
mesh_terms: D000818:Animals; D061006:Bays / Q000737:chemistry*; D015415:Biomarkers / Q000032:analysis; D001938:Brazil; D002104:Cadmium / Q000032:analysis; D003300:Copper / Q000032:analysis; D004784:Environmental Monitoring; D005880:Gills / Q000737:chemistry; D007854:Lead / Q000032:analysis; D008099:Liver / Q000737:chemistry; D008668:Metallothionein / Q000032:analysis*; D019216:Metals, Heavy / Q000032:analysis*; D009532:Nickel / Q000032:analysis; D023701:Smegmamorpha / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D015415:Biomarkers; D019216:Metals, Heavy; D014874:Water Pollutants, Chemical; D002104:Cadmium; D007854:Lead; D003300:Copper; D009532:Nickel; D008668:Metallothionein
keywords: Environmental contamination; Metallothionein; Metals; Mugil cephalus