title: Comparison of the most common isolates of postoperative endophthalmitis in South Korea; Enterococcus species vs coagulase-negative staphylococci.
abstract: To compare the related factors or manifestations of the two most common isolates of post-operative endophthalmitis, which were Enterococcus spp. and coagulase-negative staphylococci (CNS) in South Korea.
  
  
  
  Medical records were reviewed for cases of post-operative endophthalmitis caused by Enterococcus spp. and CNS at eight institutions between January 2004 and July 2010. Various factors including age, sex, residence, systemic diseases, smoking and drinking history, and best corrected visual acuity, and length of time between causative intraocular surgery and symptom development were compared between the two groups.
  
  
  
  The total number of post-operative endophthalmitis cases was 128 and in 116 cases, microbiological culture tests from the aqueous humor or vitreous were performed. Among these cases, 67 (57.8%) were culture proven. Among these 67 cases, 19 (28.4%) were caused by Enterococcus spp., 14 (20.9%) were caused by Staphylococcus epidermidis endophthalmitis, and 5 (7.5%) were caused by other CNS spp. Age, sex, causative procedure, past medical history, social history, and laterality were not different in the two groups. Mean initial and final visual acuity were significantly worse in the Enterococcus spp. endophthalmitis group than in the CNS group (p = 0.049, 0.042, respectively). Length of time between the causative procedure and symptom development was significantly shorter in cases of Enterococcus spp. endophthalmitis (p = 0.004).
  
  
  
  Enterococcus spp. induce more severe and rapid-onset postoperative endophthalmitis than CNS. Infectious endophthalmitis developed within 2 days after cataract operation could be caused by Enterococcus spp. and have chance to be poor prognosis in South Korea.
authors.affiliation: Department of Ophthalmology, College of Medicine, Kosin University, 262 Gamchun-ro, Seo-gu, Busan, South Korea.
authors.forename: Ki Yup
authors.initials: KY
authors.lastname: Nam
authors.affiliation: Department of Ophthalmology, College of Medicine, Inje University, Busan, South Korea.
authors.forename: Hyun Wong
authors.initials: HW
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, College of Medicine, Dong-A University, Busan, South Korea.
authors.forename: Woo Jin
authors.initials: WJ
authors.lastname: Jeung
authors.affiliation: Department of Ophthalmology, Maryknoll Hospital, Busan, South Korea.
authors.forename: Jung Min
authors.initials: JM
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Gyeongsang National University, Jinju, South Korea.
authors.forename: Jong Moon
authors.initials: JM
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Gyeongsang National University, Jinju, South Korea.
authors.forename: In Young
authors.initials: IY
authors.lastname: Chung
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Gyeongsang National University, Jinju, South Korea.
authors.forename: Yong Seop
authors.initials: YS
authors.lastname: Han
authors.affiliation: GM St. Mary Eye Clinic, Busan, South Korea.
authors.forename: Bu Sup
authors.initials: BS
authors.lastname: Oum
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Busan National University, Busan, South Korea.
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Busan National University, Busan, South Korea.
authors.forename: Ik Soo
authors.initials: IS
authors.lastname: Byon
authors.affiliation: Nunevit Eye Clinic, Busan, South Korea.
authors.forename: Il Han
authors.initials: IH
authors.lastname: Yun
authors.affiliation: Department of Ophthalmology, College of Medicine, Inje University, Busan, South Korea.
authors.forename: Joo Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Sungmo Eye Hospital, Busan, South Korea.
authors.forename: Hee Sung
authors.initials: HS
authors.lastname: Yoon
authors.affiliation: Crystal Eye Clinic, Busan, South Korea.
authors.forename: Dong
authors.initials: D
authors.lastname: Park
authors.affiliation: Department of Preventive Medicine, College of Medicine, Kosin University, Busan, South Korea.
authors.forename: Byeng Chul
authors.initials: BC
authors.lastname: Yu
authors.affiliation: Department of Ophthalmology, College of Medicine, Kosin University, 262 Gamchun-ro, Seo-gu, Busan, South Korea. hhiatus@gmail.com.|Institute for medicine, College of Medicine, Kosin University, Busan, South Korea. hhiatus@gmail.com.
authors.forename: Sang Joon
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000378:metabolism; D003030:Coagulase / Q000378:metabolism*; D009877:Endophthalmitis / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology*; D013293:Enterococcus faecalis / Q000302:isolation & purification*; D015818:Eye Infections, Bacterial; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000382:microbiology*; D011379:Prognosis; D056910:Republic of Korea; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology; D013210:Staphylococcus / Q000201:enzymology* / Q000302:isolation & purification
chemical_list: D015415:Biomarkers; D003030:Coagulase
keywords: Coagulase negative staphylococci; Endogenous endophthalmitis; Endophthalmitis; Enterococcus faecalis; Postoperative endophthalmitis; Posttraumatic endophthalmitis; Staphylococcus epidermidis