title: Response Assessment Criteria and Their Applications in Lymphoma: Part 2.
abstract: Interim and end-of-treatment PET/CT have become central to the evaluation of Hodgkin and non-Hodgkin lymphoma. This review article seeks to aid clinical decision making by providing an overview of available data on the diagnostic and prognostic value of PET/CT imaging for response assessment and pretransplant evaluation in lymphoma. The relative strengths and limitations of these techniques in various disease subtypes and clinical scenarios are explored, along with their current standards for reporting and latest developments. Particular attention is given to response-adapted therapy, which is emerging as a cornerstone of clinical management.
authors.affiliation: Stanford University Medical Center, Stanford, California mateenm@stanford.edu.
authors.forename: Mateen C
authors.initials: MC
authors.lastname: Moghbel
authors.affiliation: Stanford University Medical Center, Stanford, California.
authors.forename: Erik
authors.initials: E
authors.lastname: Mittra
authors.affiliation: Antoine Lacassagne Cancer Center, Nice University, Nice, France.
authors.forename: Andrea
authors.initials: A
authors.lastname: Gallamini
authors.affiliation: Kaiser Permanente, Santa Clara, California.
authors.forename: Ryan
authors.initials: R
authors.lastname: Niederkohr
authors.affiliation: Washington University, St. Louis, Missouri.
authors.forename: Delphine L
authors.initials: DL
authors.lastname: Chen
authors.affiliation: McMaster University, Hamilton, Ontario, Canada.
authors.forename: Katherine
authors.initials: K
authors.lastname: Zukotynski
authors.affiliation: University of British Columbia, Vancouver, British Columbia, Canada; and.
authors.forename: Helen
authors.initials: H
authors.lastname: Nadel
authors.affiliation: Mount Sinai Hospital, New York, New York.
authors.forename: Lale
authors.initials: L
authors.lastname: Kostakoglu
mesh_terms: D000465:Algorithms; D020000:Decision Support Systems, Clinical; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000628:therapy*; D017063:Outcome Assessment, Health Care / Q000379:methods*; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: PET/CT response assessment; lymphoma; response-adapted therapy