title: Intraductal papillary neoplasm of the bile duct: a case report.
abstract: Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors, characterized by papillary growth within the bile duct lumen and is regarded as a biliary counterpart of intraductal papillary mucinous neoplasm (IPMN) of the pancreas. IPNBs are mainly found in patients from Far Eastern areas, where hepatolithiasis and clonorchiasis are endemic. The Western experience, however, remains limited. In this article, we report a 56-year-old man, referred to our hospital because of deranged liver function tests. Further imaging modalities showed a cystic lesion of 9 cm diameter, arising from the left hepatic duct. Inlying was a heterogeneous, lobulated mass. The patient underwent a left hemihepatectomy and adjuvant chemotherapy. Despite recent advanced technologies, diagnosis of IPNB is still challenging, especially in western countries due to its rarity. Early identification and resection of lesions, even in asymptomatic or minimally symptomatic patients, are however important prognostic factors.
authors.affiliation: a Department of General and Abdominal Surgery , AZ Klina Brasschaat , Brasschaat , Belgium.
authors.forename: Karen
authors.identifier: http://orcid.org/0000-0002-1166-2267
authors.initials: K
authors.lastname: Peeters
authors.affiliation: a Department of General and Abdominal Surgery , AZ Klina Brasschaat , Brasschaat , Belgium.
authors.forename: Peter
authors.identifier: http://orcid.org/0000-0001-6009-078X
authors.initials: P
authors.lastname: Delvaux
authors.affiliation: a Department of General and Abdominal Surgery , AZ Klina Brasschaat , Brasschaat , Belgium.
authors.forename: Frederik
authors.initials: F
authors.lastname: Huysentruyt
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000175:diagnosis* / Q000628:therapy*; D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D001653:Bile Ducts, Intrahepatic; D006801:Humans; D008297:Male; D008875:Middle Aged
keywords: Bile duct carcinoma; Intraductal papillary neoplasm