title: Predictors of Liver Transplant Patient Survival.
abstract: Liver transplantation is a costly and risky procedure, representing 25 050 procedures worldwide in 2013, with 6729 procedures performed in the United States in 2014. Considering the scarcity of organs and uncertainty regarding prognosis, limited studies address the variety of risk factors before transplantation that might contribute to predicting patient's survival and therefore developing better models that address a holistic view of transplant patients. This critical review aimed to identify predictors of liver transplant patient survival included in large-scale studies and assess the gap in risk factors from a holistic approach using the Wellbeing Model and the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement.
  
  
  
  Search of the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medline, and PubMed from the 1980s to July 2014.
  
  
  
  Original longitudinal large-scale studies, of 500 or more subjects, published in English, Spanish, or Portuguese, which described predictors of patient survival after deceased donor liver transplantation.
  
  
  
  Predictors were extracted from 26 studies that met the inclusion criteria.
  
  
  
  Each article was reviewed and predictors were categorized using a holistic framework, the Wellbeing Model (health, community, environment, relationship, purpose, and security dimensions).
  
  
  
  The majority (69.7%) of the predictors represented the Wellbeing Model Health dimension. There were no predictors representing the Wellbeing Dimensions for purpose and relationship nor emotional, mental, and spiritual health. This review showed that there is rigorously conducted research of predictors of liver transplant survival; however, the reported significant results were inconsistent across studies, and further research is needed to examine liver transplantation from a whole-person perspective.
authors.affiliation: 1 School of Nursing, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Lisiane
authors.initials: L
authors.lastname: Pruinelli
authors.affiliation: 1 School of Nursing, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Karen A
authors.initials: KA
authors.lastname: Monsen
authors.affiliation: 2 School of Nursing and College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Cynthia R
authors.initials: CR
authors.lastname: Gross
authors.affiliation: 3 Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, USA.
authors.forename: David M
authors.initials: DM
authors.lastname: Radosevich
authors.affiliation: 4 Department of Health Science Research, Mayo Clinic Rochester, Rochester, MN, USA.
authors.forename: György J
authors.initials: GJ
authors.lastname: Simon
authors.affiliation: 5 School of Nursing and Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Bonnie L
authors.initials: BL
authors.lastname: Westra
mesh_terms: D006085:Graft Survival; D006801:Humans; D016031:Liver Transplantation / Q000401:mortality*; D012307:Risk Factors; D015996:Survival Rate; D014481:United States
keywords: body regions; liver transplant predictors; liver transplant recipient; liver transplantation; patient survival; well-being