title: The Kidney in Hypertension.
abstract: Hypertension is the second most common cause of chronic kidney disease (CKD) and is a potentiator of kidney failure when accompanying disease. CKD is a common cause of resistant hypertension. Nephropathy progression has dramatically slowed over the past 3 decades from an average of 8 to between 2-3 mL/min per year regardless of diabetes status. The incidence of very high albuminuria as well as progression from high albuminuria very high albuminuria has substantially decreased over the past 3 decades. This improvement relates to better blood pressure control using agents that slow nephropathy as well as better glycemic and cholesterol control.
authors.affiliation: Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, ASH Comprehensive Hypertension Center, The University of Chicago Medicine, 5841 South Maryland Avenue, MC 1027, Chicago, IL 60637, USA.
authors.forename: Hillel
authors.initials: H
authors.lastname: Sternlicht
authors.affiliation: Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, ASH Comprehensive Hypertension Center, The University of Chicago Medicine, 5841 South Maryland Avenue, MC 1027, Chicago, IL 60637, USA. Electronic address: gbakris@medicine.bsd.uchicago.edu.
authors.forename: George L
authors.initials: GL
authors.lastname: Bakris
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D018450:Disease Progression; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology*; D011507:Proteinuria / Q000209:etiology; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control*; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents
keywords: Diabetes; Hypertension; Kidney; Outcomes; Renal