title: [Effects of organochloride pesticides on dyslipidemias].
abstract: Dyslipidemias is one important risk factor associated with chronic diseases. Persistent organic pollutants are resistant to degradation and can be bio-accumulated and magnified through the food chain. Recently, the relation between dyslipidemias and organochlorine pesticides has attracted more attentions. In this review, we explored the distribution of organochloride pesticides in the environment and human body, as well as the possible underlying mechanisms of the association between dyslipidemias and organochloride pesticides, including accumulation and release of organochloride, simulation of estrogen, impact on PPARs, the metabolic fingerprint, and the inflammatory reaction.
authors.affiliation: Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
authors.forename: W T
authors.initials: WT
authors.lastname: Shao
authors.forename: A H
authors.initials: AH
authors.lastname: Gu
mesh_terms: D050171:Dyslipidemias / Q000139:chemically induced* / Q000453:epidemiology / Q000503:physiopathology*; D004785:Environmental Pollutants / Q000009:adverse effects / Q000506:poisoning*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000506:poisoning; D009930:Organic Chemicals; D010575:Pesticides / Q000009:adverse effects / Q000506:poisoning*; D012307:Risk Factors
chemical_list: D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D009930:Organic Chemicals; D010575:Pesticides