title: Relationship of anthropometric measures with Knee Osteoarthritis in diabetes mellitus.
abstract: OBJECTIVE
  To determine the frequency of knee osteoarthritis in adult patients with Diabetes mellitus and its association with body mass index (BMI) in kg/m2and waist circumference (WC).
  
  
  METHODS
  This is a cross-sectional comparative study at a tertiary hospital based in an industrial area of Karachi. Patient population comprised of all adult diabetic subjects. Clinical and demographic data was obtained with detailed musculoskeletal examination on all patients. BMI and WC were measured as kg/m2and cm respectively. Data was analyzed on SPSS version 15.
  
  
  RESULTS
  A total of 413 subjects were recruited. Among them diabetic and non-diabetic subjects were 210 and 203 respectively. Mean age of diabetics was 50.7+-10.2 years as compared to non-diabetic subjects i.e. 49.5+-10.5 years. Proportion of male subjects was 72(34.3%) and 71(35.0) respectively in both groups. Mean duration of diabetes was 6.2 years. Frequency of knee osteoarthritis (OA) was found to be 52(24.8%) and 54(26.6%) in diabetic and non-diabetic respectively. Among the diabetic group 6 (18%) subjects with OA had normal BMI (18.5-22.9) whereas 4 (16%) were overweight (BMI 23-24.9) and 41(27.5%) were obese(BMI ≥25). Near 98% (n=51) of the diabetic patients with OA had high waist circumference. Females (n= 42, 31.1%) were more frequent than males (n=9, 16%) in the diabetic subjects with OA and a higher WC.
  
  
  CONCLUSIONS
  Both diabetic and non diabetic group did not show any difference in the frequency of knee OA. However, frequency of knee OA showed a significant difference between overweight and obese category of BMI.WC appears as a strong predictor of knee osteoarthritis.
authors.affiliation: Saera Suhail Kidwai, MCPS, FCPS Associate Professor, United Medical and Dental College, Karachi, Pakistan.
authors.forename: Saera Suhail
authors.initials: SS
authors.lastname: Kidwai
authors.affiliation: Shaista Anwar Siddiqi, FCPS (Neurology). Strokologist.
authors.forename: Shaista Anwar
authors.initials: SA
authors.lastname: Siddiqi
authors.affiliation: Lubna Nazir, FCPS (Medicine), FCPS (Rheumatology). Liaquat National Hospital, Karachi, Pakistan.
authors.forename: Lubna
authors.initials: L
authors.lastname: Nazir
authors.affiliation: Tahira Parveen Umer, FCPS (Medicine). Liaquat National Hospital, Karachi, Pakistan.
authors.forename: Tahira Parveen
authors.initials: TP
authors.lastname: Umer
keywords: Body Mass Index (BMI); Diabetes Mellitus (DM); Knee Osteoarthritis (KOA); Waist circumference (WC)