title: A comprehensive study on HDR brachytherapy treatments of cervical cancers: using the first Co-60 BEBIG Multisource Unit in Bangladesh.
abstract: OBJECTIVE
  The report presents an extraordinary synthesis of customer acceptance procedures (CAP), quality assurance tests (QA) in the treatment of cervical cancer patients, using the first Co-60 Multisource Unit®in Bangladesh. The QA and commissioning required measurements and emergency tests verifying the functional limits of parameters acceptable for the new HDR afterloader. Acceptable limits were: 1) the deviation between specified and measured source strength: ± 3%; 2) the positional accuracy and uniformity: ± 1 mm; 3) the temporal accuracy (i.e. timer error and linearity and end error): ± 1% or 30 sec.; 4) treatment planning system (digitizer and localization software): ± 3% or 1 mm; 5) the distance from line to first dwell position and all the others: 5 mm and 10 mm (± 1 mm).
  
  
  METHODS
  Till February 2011, 47 patients were treated with HDR with more than 140 insertions applied. Amongst them, 12 patients were in stage IIB and IIIB, 22 were postoperative (IA and IB) while the remaining 13 patients were with unknown stage. All the cases with stage IIB and IIIB received concurrent chemo-radiation and brachytherapy. Postoperative patients received EBRT (50 Gy and HDR) according to the institutional protocol. CT scans were completed before HDR-plus planning with a good reproducibility (± 2%) and were documented in repeating the plan for the same set up of a patient. Absorbed dose (Gy) to a point P, at a distance of "r" in centimeters from a source of the Reference Air Kerma Rate (RAKR) has been utilized for the QA of the source, where source strength measurement was accomplished.
  
  
  RESULTS
  All methods and analysis applicable to the QA and commissioning of Co-60 have been investigated and systematically analyzed, measured and documented before the treatment of a patient. Studies and safety requirements of this HDR remote afterloader were carried out. Acceptance and the QA were imperative to justify functionality and dependability in delivering the treatment. Implications of these studies were described in detail in this paper, where equipments and guidelines of measurement parameters are enunciated.
  
  
  CONCLUSIONS
  We noted that contouring structures from CT images, prescription points for dose delivery, optimization, isodose evaluation, DVH, dwell times and a 3-D Dose reconstructed images, etc. followed by a final verification after delivering the treatment at the console, are well prepared in the new planning software. We present our material as an early preliminary report.
authors.affiliation: Radiation Oncology Division, Delta Medical College and Hospital, Dhaka, Bangladesh.
authors.forename: Sadiq R
authors.initials: SR
authors.lastname: Malik
authors.affiliation: Radiation Oncology Division, Delta Medical College and Hospital, Dhaka, Bangladesh.
authors.forename: Parvin A
authors.initials: PA
authors.lastname: Banu
authors.affiliation: Radiation Oncology Division, Delta Medical College and Hospital, Dhaka, Bangladesh.
authors.forename: Naheed
authors.initials: N
authors.lastname: Rukhsana
keywords: Co-60; HDR brachytherapy; MultiSource®; cervical cancer