title: [Metastatic disease in long bones : Review of surgical treatment options].
abstract: Surgery in metastatic bone disease is currently the most frequent type of surgery in orthopedic oncology. Improved survival rates and an increasing incidence of bone metastasis have led to an increase in complications caused by metastatic disease, such as pathological fractures or hardware failure after operative treatment. Although surgery of metastatic lesions remains a palliative therapy concept, because of sufficient therapy for the primary carcinomas, tumor-specific-oriented follow-up protocols and a variation in the prognosis for the individual entities, an individually adapted treatment strategy is necessary. Depending on the life expectancy, more aggressive surgical procedures with the goal of adequate local tumor control have come into focus. Therefore, prognosis-tailored treatment requires an experienced team and should be performed in a multidisciplinary tumor center. The current article provides an overview of recent therapy concepts for the surgical treatment including endoprosthetic reconstruction, internal fixation with either intramedullary nailing or plate fixation devices, often augmented with bone cement.
authors.affiliation: Klinik für Orthopädie und Sportorthopädie, Technische Universität München, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675, München, Deutschland. franz.liska@mri.tum.de.
authors.forename: Franz
authors.initials: F
authors.lastname: Liska
authors.affiliation: Abteilung Orthopädie und Unfallchirurgie, Klinikum Fürstenfeldbruck, Dachauer Str. 33, 82256, Fürstenfeldbruck, Deutschland.
authors.forename: Philipp
authors.initials: P
authors.lastname: Schmitz
authors.affiliation: Klinik für Orthopädie und Sportorthopädie, Technische Universität München, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675, München, Deutschland.
authors.forename: Norbert
authors.initials: N
authors.lastname: Harrasser
authors.affiliation: Klinik für Orthopädie und Sportorthopädie, Technische Universität München, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675, München, Deutschland.
authors.forename: Peter
authors.initials: P
authors.lastname: Prodinger
authors.affiliation: Klinik für Orthopädie und Sportorthopädie, Technische Universität München, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675, München, Deutschland.
authors.forename: Hans
authors.initials: H
authors.lastname: Rechl
authors.affiliation: Klinik für Orthopädie und Sportorthopädie, Technische Universität München, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675, München, Deutschland.
authors.forename: Rüdiger
authors.initials: R
authors.lastname: von Eisenhart-Rothe
mesh_terms: D001843:Bone Cements; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary*; D002173:Cancer Care Facilities; D005121:Extremities / Q000601:surgery*; D005593:Fracture Fixation, Internal / Q000379:methods; D005598:Fractures, Spontaneous / Q000175:diagnosis / Q000601:surgery; D005858:Germany; D006801:Humans; D033183:Interdisciplinary Communication; D000070516:Intersectoral Collaboration; D010166:Palliative Care; D011379:Prognosis; D019919:Prosthesis Implantation
chemical_list: D001843:Bone Cements
keywords: Cement augmentation; Cement augmented Osteosynthesis; Metastatic bone disease; Surgical therapy; Tumor prosthesis