title: Data on spermatogenesis in rat males gestationally exposed to bisphenol A and high fat diets.
abstract: This data article contains supporting information regarding the research article entitled "High butter-fat diet and bisphenol A additively impair male rat spermatogenesis" (P. Tarapore, M. Hennessy, D. Song, J. Ying, B. Ouyang, V. Govindarajah, et al.,) [1]. Sprague-Dawley females were fed AIN, high fat butter, 17α-ethinyl estradiol, or high fat butter plus four bisphenol A doses (2500 µg/kg bw-d, 250 µg/kg bw-d, 25 µg/kg bw-d, and 2.5 µg/kg bw-d) before and during pregnancy. All diets were switched to AIN after the pups were born. Male offspring received testosterone (T)- and estradiol-17β (E2)-filled implants from postnatal day 70-210 for 20 weeks (T+E2 rat model). The testes were weighed, and examined for impairments in spermatogenesis.
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Cincinnati Cancer Center, Cincinnati, Ohio, USA.
authors.forename: Pheruza
authors.initials: P
authors.lastname: Tarapore
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
authors.forename: Max
authors.initials: M
authors.lastname: Hennessy
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
authors.forename: Dan
authors.initials: D
authors.lastname: Song
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Ying
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
authors.forename: Bin
authors.initials: B
authors.lastname: Ouyang
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
authors.forename: Vinothini
authors.initials: V
authors.lastname: Govindarajah
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Cincinnati Cancer Center, Cincinnati, Ohio, USA.
authors.forename: Yuet-Kin
authors.initials: YK
authors.lastname: Leung
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, Ohio, USA; Cincinnati Cancer Center, Cincinnati, Ohio, USA; Cincinnati Veteran Affairs Hospital Medical Center, Cincinnati, Ohio, USA.
authors.forename: Shuk-Mei
authors.initials: SM
authors.lastname: Ho
keywords: BPA, bisphenol A; Bisphenol A; E2, estradiol-17β; EE2, 17α-ethinyl estradiol; Endocrine disrupting chemicals; HFB, high fat butter; HFO, high fat olive oil; High fat butter; High fat olive oil; PND, postnatal day; PS, pachytene Spermatocytes; RS, round spermatids; T, testosterone; Testis; kg bw-d, kg body-weight per day