title: Evaluation of the Effects of Conjunctivochalasis Excision on Tear Stability and Contrast Sensitivity.
abstract: Conjunctivochalasis (CCh) disrupts tear flow and damages tear film stability. This study sought to evaluate the tear stability and contrast sensitivity of patients with CCh on whom CCh excision was performed. The study included 39 eyes from 39 patients; all patients had eyes with grade 2 or 3 CCh, underwent CCh excision, and were evaluated before and three months after the surgery. The evaluated variables included the ocular surface disease index (OSDI), the tear break-up time (TBUT), corneal fluorescein staining, corneal surface irregularity, Schirmer's I test, the tear meniscus area (TMA), and contrast sensitivity. A follow-up of three months was achieved in 36 eyes for 36 patients. All parameters improved significantly after surgery (p < 0.05), except Schirmer's I test, thus suggesting that CCh excision is an effective method for reconstructing the lower tear meniscus and improving both tear film stability and corneal surface irregularity. The results further demonstrated a simultaneous increase in contrast sensitivity after surgery.
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Qiu
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
authors.forename: Mingzhou
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology, Beijing Shunyi Hospital, Beijing, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Xu
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
authors.forename: Ziyuan
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
authors.forename: Huibin
authors.initials: H
authors.lastname: Lv
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
authors.forename: Xuemin
authors.initials: X
authors.lastname: Li
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003228:Conjunctiva / Q000002:abnormalities / Q000503:physiopathology / Q000601:surgery*; D003229:Conjunctival Diseases / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D015350:Contrast Sensitivity / Q000502:physiology*; D003315:Cornea / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D015352:Dry Eye Syndromes / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D019793:Fluorescein / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013666:Tears / Q000378:metabolism*; D016896:Treatment Outcome
chemical_list: D005456:Fluorescent Dyes; D019793:Fluorescein