title: Individual differences in human brain development.
abstract: This article discusses recent scientific advances in the study of individual differences in human brain development. Focusing on structural neuroimaging measures of brain morphology and tissue properties, two kinds of variability are related and explored: differences across individuals of the same age and differences across age as a result of development. A recent multidimensional modeling study is explained, which was able to use brain measures to predict an individual's chronological age within about one year on average, in children, adolescents, and young adults between 3 and 20 years old. These findings reveal great regularity in the sequence of the aggregate brain state across different ages and phases of development, despite the pronounced individual differences people show on any single brain measure at any given age. Future research is suggested, incorporating additional measures of brain activity and function. WIREs Cogn Sci 2017, 8:e1389. doi: 10.1002/wcs.1389 For further resources related to this article, please visit the WIREs website.
authors.affiliation: Department of Neurosciences, UCSD School of Medicine, La Jolla, CA, USA.
authors.forename: Timothy T
authors.initials: TT
authors.lastname: Brown
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001921:Brain / Q000033:anatomy & histology / Q000254:growth & development* / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007206:Individuality; D059906:Neuroimaging; D055815:Young Adult