title: Factors Related to Late False Lumen Enlargement after Thoracic Stent-Graft Placement for Type B Aortic Dissection.
abstract: OBJECTIVE
  To evaluate significant factors related to delayed aortic false lumen (FL) enlargement in patients who have undergone thoracic stent-graft placement for type B aortic dissection.
  
  
  METHODS
  The study included 62 patients (45 male, 17 female) aged 26-80 years (mean age, 58.1 y) who underwent thoracic endovascular aortic repair for type B aortic dissection at a single institution between January 2005 and May 2015. Mean age of aortic dissections was 5.3 months (range, 0.1-73.3 mo). Maximum aortic diameter at presentation was 41.7 mm ± 8.3. The follow-up period ranged from 3 to 104 months (mean, 27.1 mo). Computed tomographic (CT) angiography studies were reviewed to identify FL diameter enlargements > 5 mm at different levels along and distal to the stent graft. Imaging findings and clinical variables were investigated to determine their correlation with FL enlargement.
  
  
  RESULTS
  No significant difference was found between the ages of aortic dissections in patients with and without FL enlargement (P = .26). On follow-up CT angiography, 16 patients had 2 or more communication channels between the FL and the systemic circulation, 7 of whom showed FL enlargement > 5 mm (P = .007). Twenty-seven patients showed complete FL thrombosis, none of whom had FL enlargement (P < .001).
  
  
  CONCLUSIONS
  Two or more communication channels between the FL and the systemic circulation represent a risk factor for FL enlargement regardless of the age of the dissection. Patients with thrombosis of the FL are less likely to experience FL enlargement.
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia School of Medicine, 1215 Lee St., Charlottesville, VA 22908; University of Padua, Padua, Italy. Electronic address: gasparetto.ale@gmail.com.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Gasparetto
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia School of Medicine, 1215 Lee St., Charlottesville, VA 22908; Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Kwang Bo
authors.initials: KB
authors.lastname: Park
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia School of Medicine, 1215 Lee St., Charlottesville, VA 22908.
authors.forename: Saher S
authors.initials: SS
authors.lastname: Sabri
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia School of Medicine, 1215 Lee St., Charlottesville, VA 22908.
authors.forename: Auh Whan
authors.initials: AW
authors.lastname: Park
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia School of Medicine, 1215 Lee St., Charlottesville, VA 22908.
authors.forename: Alan H
authors.initials: AH
authors.lastname: Matsumoto
authors.affiliation: Department of Radiology and Medical Imaging, University of Virginia School of Medicine, 1215 Lee St., Charlottesville, VA 22908.
authors.forename: John Fritz
authors.initials: JF
authors.lastname: Angle
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation; D000072226:Computed Tomography Angiography; D057510:Endovascular Procedures / Q000009:adverse effects* / Q000295:instrumentation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D015607:Stents; D013927:Thrombosis; D013997:Time Factors; D016896:Treatment Outcome; D066253:Vascular Remodeling; D014768:Virginia