title: Lymphadenectomy for Treatment of Early-Stage Endometrial Cancer.
abstract: OBJECTIVE
  What is the association between lymphadenectomy and survival, disease recurrence, and surgical morbidity in women with presumed early-stage, low-grade endometrial carcinoma?
  
  
  CONCLUSIONS
  The evidence from randomized clinical trials suggests that lymphadenectomy does not improve survival or decrease disease recurrence in women with early-stage, low-grade endometrial carcinoma. Furthermore lymphadenectomy is associated with an increase in both short- and long-term surgery-related systemic morbidity.
authors.affiliation: Department of Gynaecological Oncology, Cheltenham General Hospital, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, England.
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Frost
authors.affiliation: Department of Gynaecological Oncology, Musgrove Park Hospital, Taunton, England.
authors.forename: Katie E
authors.initials: KE
authors.lastname: Webster
authors.affiliation: Department of Gynaecological Oncology, Musgrove Park Hospital, Taunton, England.
authors.forename: Jo
authors.initials: J
authors.lastname: Morrison
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D016889:Endometrial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects*; D008875:Middle Aged; D009367:Neoplasm Staging; D010388:Pelvis / Q000473:pathology / Q000601:surgery*; D016032:Randomized Controlled Trials as Topic