title: Gold Nanoparticles for Diagnostics: Advances towards Points of Care.
abstract: The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems show great promise in improving sensitivity, ease of operation and portability. Despite this endeavor, most platforms have yet to reach maturity and make their way into clinics or points of care (POC). Here, we present an overview of emerging and available molecular diagnostics using AuNPs for biomedical sensing that are currently being translated to the clinical setting.
authors.affiliation: UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus da Caparica, 2829-516 Caparica, Portugal. m.cordeiro@campus.fct.unl.pt.|Rede de Química e Tecnologia (REQUIMTE), Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus da Caparica, 2829-516 Caparica, Portugal. m.cordeiro@campus.fct.unl.pt.
authors.forename: Mílton
authors.initials: M
authors.lastname: Cordeiro
authors.affiliation: UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus da Caparica, 2829-516 Caparica, Portugal. fa.carlos@campus.fct.unl.pt.
authors.forename: Fábio
authors.initials: F
authors.lastname: Ferreira Carlos
authors.affiliation: UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus da Caparica, 2829-516 Caparica, Portugal. pm.pedrosa@campus.fct.unl.pt.
authors.forename: Pedro
authors.initials: P
authors.lastname: Pedrosa
authors.affiliation: UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus da Caparica, 2829-516 Caparica, Portugal. a.lopez@campus.fct.unl.pt.
authors.forename: António
authors.initials: A
authors.lastname: Lopez
authors.affiliation: UCIBIO, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus da Caparica, 2829-516 Caparica, Portugal. pmvb@fct.unl.pt.
authors.forename: Pedro Viana
authors.initials: PV
authors.lastname: Baptista
keywords: biomolecular sensing; diagnosis; gold nanoparticles; point-of-need