title: Framingham risk score in impaired glucose tolerant population: A sub analysis of Diabetes Prevention and Awareness Program of Pakistan.
abstract: OBJECTIVE
  To assess the 10-year risk of coronary artery disease (CAD) in subjects with impaired glucose tolerance (IGT) using Framingham risk score.
  
  
  METHODS
  Data for this study was collected from Diabetes Prevention and Awareness Program. Primary prevention team visited different primary health care centers, factories, service organizations and offices within Karachi, Pakistan. IGT was diagnosed according to World Health Organization criteria after taking informed consent. Information regarding social-demography, dietary habits and physical activities were obtained by a designed questionnaire on one-to-one based interview. Framingham risk score (FRS) was used to assess risk of developing CAD.
  
  
  RESULTS
  A total of 315 subjects with IGT were recruited for the study. Mean age of subjects was 44.1 ± 9.8 years and mean BMI was 27.3 ± 5.0 kg/m2. Overall, 31.4% of the participants were at risk of having CAD. Males were 6.4 times and hypertensive subjects were 2.44 times more likely to have CAD in next 10 years.
  
  
  CONCLUSIONS
  According to the findings of the study, male and hypertensive IGT subjects were more likely to develop CAD in next 10 years. Community based awareness programs are needed to educate people regarding healthy lifestyle in order to reduce the risk of IGT and CAD.
authors.affiliation: Asher Fawwad, PhD. Associate Professor, Baqai Medical University, Senior Research Scientist, Research Department, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi, Pakistan.
authors.forename: Asher
authors.initials: A
authors.lastname: Fawwad
authors.affiliation: Hassan Moin, M.Sc. Statistician, Research Department, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi, Pakistan.
authors.forename: Hassan
authors.initials: H
authors.lastname: Moin
authors.affiliation: Iftikhar Ahmed Siddiqui, PhD. Chairman & Professor of Biochemistry, Department of Biochemistry, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi, Pakistan.
authors.forename: Iftikhar Ahmed
authors.initials: IA
authors.lastname: Siddiqui
authors.affiliation: Muhammad Zafar Iqbal Hydrie, PhD, Postdoc. Assistant Professor, Department of Biochemistry, Hamdard College of Medicine and Dentistry, Hamdard University, Karachi, Pakistan.
authors.forename: Muhammad Zafar Iqbal
authors.initials: MZ
authors.lastname: Hydrie
authors.affiliation: Abdul Basit, FRCP. Professor of Medicine, Department of Medicine, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi, Pakistan.
authors.forename: Abdul
authors.initials: A
authors.lastname: Basit
keywords: Coronary artery disease; Framingham risk score; Impaired glucose tolerance; OGTT