title: Associations between prolonged sedentary time and breaks in sedentary time with cardiometabolic risk in 10-14-year-old children: The HAPPY study.
abstract: This study examines the association between prolonged sedentary time and breaks in sedentary time with cardiometabolic risk in 10-14-year-old children. This cross-sectional design study analysed accelerometry-determined sedentary behaviour and physical activity collected over 7 days from 111 (66 girls) UK schoolchildren. Objective outcome measures included waist circumference, fasting lipids, fasting glucose, blood pressure, and cardiorespiratory fitness. Logistic regression was used for the main data analysis. After adjustment for confounders, the odds of having hypertriglyceridaemia (P = 0.03) and an increased clustered cardiometabolic risk score (P = 0.05) were significantly higher in children who engaged in more prolonged sedentary bouts per day. The number of breaks in sedentary time per day was not associated with any cardiometabolic risk factor, but longer mean duration of daily breaks in sedentary time were associated with a lower odds of having abdominal adiposity (P = 0.04) and elevated diastolic blood pressure (P = 0.01). These associations may be mediated by engagement in light activity. This study provides evidence that avoiding periods of prolonged uninterrupted sedentary time may be important for reducing cardiometabolic disease risk in children.
authors.affiliation: a Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity , University of Bedfordshire , Bedford , UK.
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Bailey
authors.affiliation: b Institute of Cellular Medicine , Newcastle University , Newcastle upon Tyne , UK.
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Charman
authors.affiliation: c Open Lab, School of Computing Science , Newcastle University , Newcastle upon Tyne , UK.
authors.forename: Thomas
authors.initials: T
authors.lastname: Ploetz
authors.affiliation: a Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity , University of Bedfordshire , Bedford , UK.
authors.forename: Louise A
authors.initials: LA
authors.lastname: Savory
authors.affiliation: d Allied & Public Health, Faculty of Medical Science , Anglia Ruskin University , Cambridge , UK.
authors.forename: Catherine J
authors.initials: CJ
authors.lastname: Kerr
mesh_terms: D061725:Accelerometry; D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D000072599:Cardiorespiratory Fitness; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002648:Child; D003430:Cross-Sectional Studies; D015444:Exercise; D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000453:epidemiology; D008055:Lipids / Q000097:blood; D008297:Male; D008659:Metabolic Diseases / Q000453:epidemiology*; D056128:Obesity, Abdominal; D012307:Risk Factors; D057185:Sedentary Behavior; D013997:Time Factors; D055105:Waist Circumference
chemical_list: D001786:Blood Glucose; D008055:Lipids
keywords: Sedentary bout; cardiometabolic risk; cardiorespiratory fitness; physical activity; sedentary time