title: Early experience and brain development.
abstract: Healthy brain development takes place within the context of individual experience. Here, we describe how certain early experiences are necessary for typical brain development. We present evidence from multiple studies showing that severe early life neglect leads to alterations in brain development, which compromises emotional, behavioral, and cognitive functioning. We also show how early intervention can reverse some of the deleterious effects of neglect on brain development. We conclude by emphasizing that early interventions that start at the earliest possible point in human development are most likely to support maximal recovery from early adverse experiences. WIREs Cogn Sci 2017, 8:e1387. doi: 10.1002/wcs.1387 For further resources related to this article, please visit the WIREs website.
authors.affiliation: Harvard Medical School, Boston Children's Hospital, Boston, MA, USA.
authors.forename: Johanna
authors.initials: J
authors.lastname: Bick
authors.affiliation: Harvard Medical School, Boston Children's Hospital, Boston, MA, USA.
authors.forename: Charles A
authors.initials: CA
authors.lastname: Nelson
mesh_terms: D000818:Animals; D001921:Brain / Q000254:growth & development* / Q000502:physiology; D001931:Brain Mapping; D017028:Caregivers; D002648:Child; D002657:Child Development / Q000502:physiology*; D006801:Humans; D007206:Individuality; D012944:Social Support