title: Vicinal Difluoroalkylation and Aminosulfonylation of Alkynes under Photoinduced Conditions.
abstract: A photoinduced vicinal difluoroalkylation and aminosulfonylation of alkynes under photocatalysis was realized. The combination of ethyl 2-bromo-2,2-difluoroacetate, alkynes, and DABCO⋅(SO2)2with hydrazines, catalyzed by 9-mes-10-methyl acridinium perchlorate in the presence of visible light, afforded (E)-ethyl 2,2-difluoro-4-aryl-4-sulfamoylbut-3-enoates in good yields with high stereoselectivity. This four-component reaction proceeds through radical addition with the insertion of sulfur dioxide.
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, P. R. China.
authors.forename: Yuanchao
authors.initials: Y
authors.lastname: Xiang
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, P. R. China.
authors.forename: Yuewen
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, P. R. China.
authors.forename: Yunyan
authors.initials: Y
authors.lastname: Kuang
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, P. R. China.|State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, P. R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
keywords: alkyne; aminosulfonylation; difluoroalkylation; photocatalysis; sulfur dioxide