title: Leukocytosis and neutrophilia after laparoscopic gastric plication.
abstract: BACKGROUND
  Laparoscopic gastric plication (LGP) is a relatively novel bariatric surgery technique. We have encountered a noticeable proportion of our LGP patients with findings such as leukocytosis and neutrophilia and hypothesized that they are part of normal body response to the operation.
  
  
  OBJECTIVE
  To evaluate the prevalence and clinical importance of leukocytosis, neutrophilia and abnormal vital signs in patients undergoing LGP during postoperative period.
  
  
  METHODS
  Forty-four consecutive LGP patients were prospectively followed for 3 months. Records of 44 laparoscopic cholecystectomy patients were also reviewed for comparison. Preoperative and postoperative laboratory test were performed. Minor and major complications were recorded during the study period.
  
  
  RESULTS
  Mean body mass index (BMI) and age were 37and 42.5, respectively. Mean hospital stay was 3.6 days (range: 3-8 days). Leukocytosis and neutrophilia were detected in 63% and 72% of the LGP patients, respectively, 48 h after the procedure. Whereas, after cholecystectomy only 38.5% and 18% of patients had leukocytosis and neutrophilia, respectively. 25% of the patients suffered from at least one minor complication after LGP. There was no mortality.
  
  
  CONCLUSIONS
  Leukocytosis and neutrophilia are very common after LGP in both the complicated and uncomplicated cases, and may be a part of normal response to surgery.
authors.affiliation: a Laparoscopic Surgery Ward , Sina Hospital, Tehran University of Medical Sciences , Tehran , Iran.|b Department of Surgery , Beth Israel Deaconess Medical Center, Harvard Medical School , Boston , MA , USA.
authors.forename: Omidreza
authors.initials: O
authors.lastname: Tabatabaie
authors.affiliation: c Laparoscopic Surgery Ward , Sina Hospital Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Siamak
authors.initials: S
authors.lastname: Maleki
authors.affiliation: d Head, Laparoscopic Surgery Ward, Sina Hospital , Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Talebpour
mesh_terms: D000328:Adult; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D015391:Gastroplasty / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects* / Q000379:methods; D007958:Leukocyte Count; D007964:Leukocytosis / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism*; D009767:Obesity, Morbid / Q000601:surgery*; D011183:Postoperative Complications / Q000097:blood / Q000503:physiopathology; D012016:Reference Values; D018570:Risk Assessment; D016896:Treatment Outcome
keywords: Bariatric surgery; laboratory data; laparoscopic surgery; obesity; plication