title: Two cases of pseudo-achalasia with lung cancer: Case report and short literature review.
abstract: Pseudo-achalasia with lung cancer is a rare complication. We present 2 cases of pseudo-achalasia with lung cancer and summarize previous reports. The previous reports suggested that lung cancer can be complicated with pseudo-achalasia caused by paraneoplastic neurological syndromes rather than direct invasion of the tumor cells to the lower esophageal sphincter, irrespective of the histology of the lung cancer; this can strongly influence the performance status. Treatment for pseudo-achalasia improves not only the symptoms, but also the performance status. Therefore, pseudo-achalasia should be considered when lung cancer patients present with dysphagia without other known causes.
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. Electronic address: taizou2001@gmail.com.
authors.forename: Taizou
authors.initials: T
authors.lastname: Hirano
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. Electronic address: miyauchi@rm.med.tohoku.ac.jp.
authors.forename: Eisaku
authors.initials: E
authors.lastname: Miyauchi
authors.affiliation: Department of Palliative Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. Electronic address: akinoue@idac.tohoku.ac.jp.
authors.forename: Akira
authors.initials: A
authors.lastname: Inoue
authors.affiliation: Department of Respiratory Medicine, Oosaki Citizen Hospital, 3-8-1 Furukawahonami Oosaki, Miyagi 989-6174, Japan. Electronic address: ryo-igusa@h-osaki.jp.
authors.forename: Ryotaro
authors.initials: R
authors.lastname: Igusa
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. Electronic address: shi-chiba@rm.med.tohoku.ac.jp.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Chiba
authors.affiliation: Department of Pathology Medicine, Oosaki Citizen Hospital, 3-8-1 Furukawahonami Oosaki, Miyagi 989-6174, Japan. Electronic address: ksakamoto-och@h-osaki.jp.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Sakamoto
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. Electronic address: sugiura@rm.med.tohoku.ac.jp.
authors.forename: Hisatoshi
authors.initials: H
authors.lastname: Sugiura
authors.affiliation: Division of Respiratory and Infection Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan. Electronic address: kikuchi@med.niigata-u.ac.jp.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kikuchi
authors.affiliation: Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. Electronic address: ichinose@rm.med.tohoku.ac.jp.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ichinose
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000175:diagnosis; D003680:Deglutition Disorders / Q000209:etiology; D004931:Esophageal Achalasia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D005260:Female; D005471:Fluoroscopy; D005774:Gastrostomy; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis; D008297:Male; D020361:Paraneoplastic Syndromes, Nervous System / Q000150:complications; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
keywords: Lung cancer; Paraneoplastic neurological syndromes; Pseudo-achalasia; Secondary achalasia