title: Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin.
abstract: The flavanol (±)-catechin shows an OH group but no 4-keto group on ring C (C3), and no conjugation between ring A and B. The related flavanone (+)-eriodictyol has a keto group on C4 but no 3-OH group on ring C. (+)-Taxifolin, another flavanone, has an OH on C3 and a keto group on C4 of the C ring. Deoxyribose degradation assay systems, with hydrogen peroxide and ascorbic acid either added or omitted, were performed in variants in which Fe(III) was added in a complex with ethylenediaminetetraacetic acid (EDTA). In combination with differential pulse voltammetry (DVP), the specific redox-chemical contributions of the ring Am-dihydroxyl groups could be explored more specifically in addition to those of the traditionally investigatedo-dihydroxyl groups of ring B.
authors.affiliation: Division of Molecular Systems Biology, Department of Ecogenomics and Systems Biology, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria. vladimir.chobot@univie.ac.at.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Chobot
authors.affiliation: Department of Plant Biochemistry, Albrecht-von-Haller Institut, Georg-August-Universität Göttingen, Justus-von-Liebig-Weg 11, D-37077 Göttingen, Germany. franz.hadacek@biologie.uni-goettingen.de.
authors.forename: Franz
authors.initials: F
authors.lastname: Hadacek
authors.affiliation: Division of Molecular Systems Biology, Department of Ecogenomics and Systems Biology, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria. gert.bachmann@univie.ac.at.
authors.forename: Gert
authors.initials: G
authors.lastname: Bachmann
authors.affiliation: Division of Molecular Systems Biology, Department of Ecogenomics and Systems Biology, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria. wolfram.weckwerth@univie.ac.at.
authors.forename: Wolfram
authors.initials: W
authors.lastname: Weckwerth
authors.affiliation: Division of Molecular Systems Biology, Department of Ecogenomics and Systems Biology, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria. lenka.kubicova@univie.ac.at.
authors.forename: Lenka
authors.initials: L
authors.lastname: Kubicova
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D002392:Catechin / Q000737:chemistry*; D004492:Edetic Acid / Q000737:chemistry; D044950:Flavanones / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D000975:Antioxidants; D044950:Flavanones; D005419:Flavonoids; D002392:Catechin; D004492:Edetic Acid; D011794:Quercetin; C003377:taxifolin; C007619:eriodictyol
keywords: Fenton reaction; deoxyribose degradation assay; differential pulse voltammetry; flavonoids; redox chemistry