title: Scalable preparation, characterization, and application of alkali-treated starch as a new organic base catalyst.
abstract: Preparation, characterization, and application of alkali starch (AS) given by dry co-grinding of starch and alkali is described in this work. Grinding using a mortar (agate) and pestle or, more conveniently, a ball mill has been found to be satisfactory for the preparation of the AS. The AS products were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) and x-ray fluorescence (XRF) analyses. The base capacities of ASs were 4.25-4.45 mmol/g, respectively. AS is a low cost and easy to handle base catalyst that showed promising catalytic performance in the synthesis of a dihydroquinazoline-based antibacterial drug that involves tandem hydration or decarboxylative amidation, imination, and Aza-Michael reactions.
authors.affiliation: Department of Chemistry, Faculty of Science, Yazd University, Yazd 89195-741, Iran. Electronic address: ftamaddon@yazd.ac.ir.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Tamaddon
authors.affiliation: Department of Chemistry, Faculty of Science, Yazd University, Yazd 89195-741, Iran. Electronic address: Marshal67FH@yahoo.com.
authors.forename: MohammadTaghi
authors.initials: M
authors.lastname: KazemiVarnamkhasti
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D008855:Microscopy, Electron, Scanning; D009584:Nitrogen / Q000737:chemistry; D011799:Quinazolines / Q000138:chemical synthesis / Q000737:chemistry; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D013213:Starch / Q000737:chemistry*; D014783:Viscosity; D003313:Zea mays / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D011799:Quinazolines; D013213:Starch; D009584:Nitrogen
keywords: Alkaline starch; Anionic polymer; Antibacterial drug; Base catalyst