title: Fanconi Syndrome Associated with Hyponatremia in Two Patients with Legionella Pneumonia.
abstract: Legionella pneumophila is a cause of community-acquired pneumonia that is reported to induce electrolyte disorders, including hyponatremia, hypokalemia, and hypophosphatemia. We herein report two Japanese men with Legionella pneumonia and hyponatremia and hypophosphatemia. These findings were associated with an elevation of urinary low-molecular-weight tubular protein, including urinary β2-microglobulin, N-acetyl-β-D-glucosaminidase, the fractional excretion of phosphate and uric acid, and the presence of glycosuria and panaminoaciduria, suggesting that their electrolyte disorders had been caused by Fanconi syndrome. In these two cases, hyponatremia was probably due to salt wasting. Electrolyte disorders caused by Legionella pneumonia are corrected by treatment of the primary disease and fluid administration.
authors.affiliation: Department of Nephrology, Toyohashi Municipal Hospital, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Ryuge
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Ito
authors.forename: Taishi
authors.initials: T
authors.lastname: Yamakawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tanaka
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Yasui
authors.forename: Shuko
authors.initials: S
authors.lastname: Mashimo
authors.forename: Kenshi
authors.initials: K
authors.lastname: Watanabe
authors.forename: Rie
authors.initials: R
authors.lastname: Nomura
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Suganuma
authors.forename: Shoichi
authors.initials: S
authors.lastname: Maruyama
mesh_terms: D000368:Aged; D005198:Fanconi Syndrome / Q000097:blood / Q000209:etiology*; D005440:Fluid Therapy; D006801:Humans; D007010:Hyponatremia / Q000097:blood / Q000150:complications* / Q000628:therapy; D016952:Legionella pneumophila / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012964:Sodium / Q000097:blood*
chemical_list: D012964:Sodium