title: Tuberculosis and the Heart.
abstract: Owing to the high prevalence of tuberculosis (TB) and human immunodeficiency virus/AIDS, tuberculous heart disease remains an important problem in TB endemic areas. In this review, we reiterate salient aspects of the traditional understanding and approach to its management, and provide important updates on the pathophysiology, diagnosis, and treatment garnered over the past decade of focused clinical and basic science research. We emphasize that, if implemented widely, these improved evidence-based approaches to the disease can build on the early progress made in treating tuberculous heart disease and help further the goal of significantly reducing its historically high morbidity and mortality.
authors.affiliation: Division of Cardiology, Department of Medicine, Groote Schuur Hospital, University of Cape Town, E17 Cardiac Clinic, New Groote Schuur Hospital, Anzio Road, Observatory 7925, Cape Town, South Africa.
authors.forename: Arthur K
authors.initials: AK
authors.lastname: Mutyaba
authors.affiliation: Division of Cardiology, Department of Medicine, Groote Schuur Hospital, University of Cape Town, E17 Cardiac Clinic, New Groote Schuur Hospital, Anzio Road, Observatory 7925, Cape Town, South Africa. Electronic address: mpiko.ntsekhe@uct.ac.za.
authors.forename: Mpiko
authors.initials: M
authors.lastname: Ntsekhe
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D003906:Developing Countries; D006801:Humans; D009017:Morbidity / Q000639:trends; D010495:Pericarditis, Tuberculous / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D012959:Socioeconomic Factors
chemical_list: D000995:Antitubercular Agents
keywords: Tuberculosis; Tuberculous aortitis; Tuberculous myocarditis; Tuberculous myopericarditis; Tuberculous pericarditis