title: A survey of pediatric hematology/oncology specialists regarding management of central line associated venous thrombosis.
abstract: Central venous catheters (CVCs) account for the largest proportion of thrombotic events in pediatric patients. Questions remain regarding adequate treatment and prevention methods. We surveyed pediatric hematology/oncology specialists, using hypothetical cases to assess management strategies for acute CVC thrombosis and secondary prevention. Survey respondents varied in the use of the thrombophilia evaluation (33.3%, 41/123) and duration of treatment (6 weeks: 54.1%, 66/122). Secondary CVC prophylaxis was utilized by 36.6% (45/123) of respondents and by 24.4% (30/123) but only if there was a documented thrombophilia. This heterogeneity highlights the need for clinical studies to address these important clinical questions.
authors.affiliation: Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.|Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Char M
authors.initials: CM
authors.lastname: Witmer
authors.affiliation: Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
authors.forename: Emily
authors.initials: E
authors.lastname: Sauck
authors.affiliation: Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.|Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Leslie J
authors.initials: LJ
authors.lastname: Raffini
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D062905:Central Venous Catheters / Q000009:adverse effects*; D006405:Hematology; D006801:Humans; D008495:Medical Oncology; D010820:Physicians; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000925:Anticoagulants
keywords: central venous catheter; pediatric; survey; thrombosis