title: A comparison of the brainstem auditory evoked response in healthy ears of unilaterally deaf dogs and bilaterally hearing dogs.
abstract: OBJECTIVE
  Auditory plasticity in response to unilateral deafness has been reported in various animal species. Subcortical changes occurring in unilaterally deaf young dogs using the brainstem auditory evoked response have not been evaluated yet. The aim of this study was to assess the brainstem auditory evoked response findings in dogs with unilateral hearing loss, and compare them with recordings obtained from healthy dogs.
  
  
  METHODS
  Brainstem auditory evoked responses (amplitudes and latencies of waves I, II, III, V, the V/I wave amplitude ratio, wave I-V, I-III and III-V interpeak intervals) were studied retrospectively in forty-six privately owned dogs, which were either unilaterally deaf or had bilateral hearing. The data obtained from the hearing ears in unilaterally deaf dogs were compared to values obtained from their healthy littermates.
  
  
  RESULTS
  Statistically significant differences in the amplitude of wave III and the V/I wave amplitude ratio at 75 dB nHL were found between the group of unilaterally deaf puppies and the control group. The recordings of dogs with single-sided deafness were compared, and the results showed no statistically significant differences in the latencies and amplitudes of the waves between left- (AL) and right-sided (AR) deafness.
  
  
  CONCLUSIONS
  The recordings of the brainstem auditory evoked response in canines with unilateral inborn deafness in this study varied compared to recordings from healthy dogs. Future studies looking into electrophysiological assessment of hearing in conjunction with imaging modalities to determine subcortical auditory plasticity and auditory lateralization in unilaterally deaf dogs are warranted.
authors.affiliation: Department of Internal Diseases with Clinic for Horses, Dogs and Cats, The Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366, Wrocław, Poland. marta.plonek@up.wroc.pl.
authors.forename: M
authors.initials: M
authors.lastname: Plonek
authors.affiliation: Department of Internal Diseases with Clinic for Horses, Dogs and Cats, The Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366, Wrocław, Poland.|Centre for Experimental Diagnostics and Biomedical Innovations, Grunwaldzki sq. 47, 50-366, Wroclaw, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Nicpoń
authors.affiliation: Department of Internal Diseases with Clinic for Horses, Dogs and Cats, The Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366, Wrocław, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Kubiak
authors.affiliation: Department of Internal Diseases with Clinic for Horses, Dogs and Cats, The Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366, Wrocław, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Wrzosek
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000151:congenital / Q000503:physiopathology*; D004285:Dogs; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D046088:Hearing Loss, Unilateral / Q000151:congenital / Q000503:physiopathology / Q000662:veterinary*; D008297:Male
keywords: Amplitude; Congenital sensorineural deafness; Latency; Subcortical auditory plasticity