title: New Challenges in the Treatment of Patients With Left Ventricular Support: LVAD Thrombosis.
abstract: Mechanical circulatory support has revolutionized the treatment of heart failure, affording patients significantly improved survival and quality of life. However, further advancements in this technology have been hindered by adverse events, particularly gastrointestinal bleeding, driveline infection, stroke, and device thrombosis. Recently, there has been a renewed focus on device thrombosis as the reported incidence has increased. This review focuses on an update on the diagnostic modalities and current treatment algorithms of this serious complication.
authors.affiliation: Section of Cardiology, University of Chicago, Chicago, IL, USA.
authors.forename: Ann B
authors.initials: AB
authors.lastname: Nguyen
authors.affiliation: Section of Cardiology, University of Chicago, Chicago, IL, USA.
authors.forename: Nir
authors.initials: N
authors.lastname: Uriel
authors.affiliation: Section of Cardiology, University of Chicago, Chicago, IL, USA. sadatya@uchicago.edu.
authors.forename: Sirtaz
authors.initials: S
authors.lastname: Adatya
mesh_terms: D006333:Heart Failure / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D011788:Quality of Life; D013927:Thrombosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy
keywords: Antifactor Xa; Device thrombosis; Echocardiographic ramp test; Thrombolytics