title: Development of a taxonomy for pharmaceutical interventions in HIV+ patients based on the CMO model.
abstract: OBJECTIVE
  To agree on a proposal for pharmaceutical interventions and establish their classification taxonomy according to the CMO-Pharmaceutical Care Model (Capacity-Motivation- Opportunity).
  
  
  METHODS
  A study conducted between March and May, 2016. Two phases of development were defined. A literature review was initially conducted. Then, the DELPHI-Rand-UCLA methodology was used in order to reach a consensus about those interventions selected, and to define the taxonomy. Fifteen (15) experts, specialists in Pharmaceutical Care for HIV+ patients, were selected. This selection was explicitly conducted, following a protocol in order to avoid any bias. An initial proposal was developed according to the interventions extracted from Phase 1. These were tentatively classified according to the CMO Model, in a category based on their design and utility. Three issues were raised from the initial question: Do you agree with the proposed classification? If not, there was an option to re-categorize. Additionally, they were asked about the importance, priority and impact to achieve pharmacotherapeutic objectives that they would assign to it. Interventions were classified according to the degree of agreement. Once a consensus was reached, the final taxonomy was established.
  
  
  RESULTS
  Eighteen (18) articles were finally considered. The initial proposal included 20 pharmaceutical interventions with the following classification: seven in Capacity, eight in Motivation, and five in Opportunity. Those interventions considered to have greater importance and priority were: Review and Validation, Safety, and Adherence. The interventions with the greatest impact were: Review and Validation, Coordination, Adherence, and Motivation. On the other hand, the lowest scores for importance were for: Planning and Social Coordination; and in terms of impact: Social Coordination.
  
  
  CONCLUSIONS
  The taxonomy reached by consensus will allow to classify pharmaceutical interventions with the new model, and therefore to conduct an improved research and patient care.
authors.affiliation: Unidad de Gestión Clínica de Farmacia. Hospital Universitario de Valme. AGS Sevilla-Sur.. ralejandro.morillo.sspa@juntadeandalucia.es.
authors.forename: Ramón
authors.initials: R
authors.lastname: Morillo Verdugo
authors.affiliation: Facultad de Farmacia. Universidad de Sevilla. Spain.. andreliz16@hotmail.com.
authors.forename: Andrea Lisbeth
authors.initials: AL
authors.lastname: Villarreal Arevalo
authors.affiliation: Facultad de Farmacia. Universidad de Sevilla. Spain.. aldesoto@us.es.
authors.forename: Maria
authors.initials: M
authors.lastname: Alvarez De Sotomayor
authors.affiliation: Unidad de Gestión Clínica de Farmacia. Hospital Universitario de Valme. AGS Sevilla-Sur.. awi_water@hotmail.com.
authors.forename: Maria de Las Aguas
authors.initials: ML
authors.lastname: Robustillo Cortes
mesh_terms: D002965:Classification; D032921:Consensus; D006679:HIV Seropositivity / Q000145:classification* / Q000188:drug therapy*; D019538:Health Care Surveys; D006801:Humans; D054539:Medication Therapy Management / Q000145:classification*; D017146:Models, Organizational; D010349:Patient Compliance