title: Severe endocarditis and open-heart surgery during pregnancy.
abstract: A woman aged 36 years G2P1 presented at our outpatient clinic with symptoms of discomfort, dyspnoea and fever at a gestational age of 17 weeks. She was subsequently diagnosed with severe endocarditis with a large vegetation on the mitral valve. She underwent open chest mitral valve surgery while on cardiopulmonary bypass (CPB) within a few days. Such surgical intervention is not only associated with increased maternal risks, but also with severe fetal morbidity and mortality. In such patients, certain perioperative measures can diminish these risks. In this case, mitral valve plasty was successfully performed and no maternal complications occurred. 22 weeks later, she had an at term vaginal delivery of a healthy son.
authors.affiliation: Department of Obstetrics and Gynaecology, Onze Lieve Vrouwe Gasthuis locatie Oost, Amsterdam, The Netherlands.
authors.forename: Arnoud W
authors.initials: AW
authors.lastname: Kastelein
authors.affiliation: Department of Cardiothoracic Surgery, Onze Lieve Vrouwe Gasthuis locatie Oost, Amsterdam, The Netherlands.
authors.forename: Nanne Y
authors.initials: NY
authors.lastname: Oldenburger
authors.affiliation: Department of Obstetrics and Gynaecology, Onze Lieve Vrouwe Gasthuis locatie Oost, Amsterdam, The Netherlands.
authors.forename: Mariëlle G
authors.initials: MG
authors.lastname: van Pampus
authors.affiliation: Department of Obstetrics and Gynaecology, Onze Lieve Vrouwe Gasthuis locatie Oost, Amsterdam, The Netherlands.
authors.forename: Erica W M
authors.initials: EW
authors.lastname: Janszen
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000379:methods*; D002315:Cardiopulmonary Bypass / Q000379:methods*; D004696:Endocarditis / Q000601:surgery*; D005260:Female; D006801:Humans; D050498:Live Birth; D008943:Mitral Valve / Q000601:surgery; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000601:surgery*; D011262:Pregnancy Trimester, Second