title: The Limbal Epithelial Progenitors in the Limbal Niche Environment.
abstract: Limbal epithelial progenitors are stem cells located in limbal palisades of vogt. In this review, we present the audience with recent evidence that limbal epithelial progenitors may be a powerful stem cell resource for the cure of human corneal stem cell deficiency. Further understanding of their mechanism may shed lights to the future successful application of stem cell therapy not only to the eye tissue, but also to the other tissues in the human body.
authors.affiliation: Research and Development Department, TissueTech, Inc., 7000 SW 97th Avenue, Suite 212, Miami, FL 33173, USA.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Sun
authors.affiliation: Department of Ophthalmology, Yan' An Hospital of Kunming City, Kunming, 650051, China.
authors.forename: Yongsong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Research and Development Department, TissueTech, Inc., 7000 SW 97th Avenue, Suite 212, Miami, FL 33173, USA.
authors.forename: Shuangling
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
authors.forename: Subo
authors.initials: S
authors.lastname: Cai
authors.affiliation: Research and Development Department, TissueTech, Inc., 7000 SW 97th Avenue, Suite 212, Miami, FL 33173, USA.
authors.forename: Yingting
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Shenzhen Eye Hospital, School of Optometry & Ophthalmology of Shenzhen University, Shenzhen Key Laboratory of Department of Ophthalmology, Shenzhen, 518000, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Guo
mesh_terms: D004847:Epithelial Cells / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D016850:Limbus Corneae / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D055153:Stem Cell Niche / Q000502:physiology*; D013234:Stem Cells / Q000378:metabolism / Q000502:physiology*
keywords: Limbal epithelial progenitors; stem cell