title: Vitamin D Receptor TaqI Gene Polymorphism and Dental Caries in Czech Children.
abstract: We analyzed the VDR TaqI (rs731236) gene polymorphism in children with and those without dental caries.
  
  
  
  A total of 388 subjects, 153 caries-free (with decayed/missing/filled teeth [DMFT] = 0) and 235 children with dental caries (DMFT ≥1), were genotyped by the TaqMan method.
  
  
  
  Although no significant differences in VDR TaqI allele and genotype frequencies between caries-free and caries-affected children were detected, a significant association between this polymorphism and gingivitis was found (p < 0.05).
  
  
  
  In contrast to previous studies from China and Turkey, the VDR TaqI gene variant cannot be used as a marker for identification of Czech children with increased dental caries risk.
authors.affiliation: Clinic of Stomatology, Institutions Shared with St. Anne's Faculty Hospital, Masaryk University, Brno, Czech Republic.
authors.forename: Lydie
authors.initials: L
authors.lastname: Izakovicova Holla
authors.forename: Petra
authors.initials: P
authors.lastname: Borilova Linhartova
authors.forename: Jakub
authors.initials: J
authors.lastname: Kastovsky
authors.forename: Michaela
authors.initials: M
authors.lastname: Bartosova
authors.forename: Kristina
authors.initials: K
authors.lastname: Musilova
authors.forename: Lubomir
authors.initials: L
authors.lastname: Kukla
authors.forename: Martina
authors.initials: M
authors.lastname: Kukletova
mesh_terms: D000293:Adolescent; D000483:Alleles; D016022:Case-Control Studies; D018153:Czech Republic / Q000453:epidemiology; D004245:DMF Index; D003731:Dental Caries / Q000453:epidemiology / Q000235:genetics*; D015252:Deoxyribonucleases, Type II Site-Specific; D005260:Female; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005838:Genotype; D005891:Gingivitis / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D008297:Male; D016017:Odds Ratio; D020641:Polymorphism, Single Nucleotide; D018167:Receptors, Calcitriol / Q000235:genetics*
chemical_list: D018167:Receptors, Calcitriol; C579457:VDR protein, human; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases