title: Functional and motor gastrointestinal disorders.
abstract: This article discusses the most interesting presentations at Digestive Disease Week, held in San Diego, in the field of functional and motor gastrointestinal disorders. One of the most important contributions was undoubtedly the presentation of the new Rome IV diagnostic criteria for functional gastrointestinal disorders. We therefore devote some space in this article to explaining these new criteria in the most common functional disorders. In fact, there has already been discussion of data comparing Rome IV and Rome III criteria in the diagnosis of irritable bowel syndrome, confirming that the new criteria are somewhat more restrictive. From the physiopathological point of view, several studies have shown that the aggregation of physiopathological alterations increases symptom severity in distinct functional disorders. From the therapeutic point of view, more data were presented on the efficacy of acotiamide and its mechanisms of action in functional dyspepsia, the safety and efficacy of domperidone in patients with gastroparesis, and the efficacy of linaclotide both in irritable bowel syndrome and constipation. In irritable bowel syndrome, more data have come to light on the favourable results of a low FODMAP diet, with emphasis on its role in modifying the microbiota. Finally, long-term efficacy data were presented on the distinct treatment options in achalasia.
authors.affiliation: Instituto de Trastornos Funcionales y Motores Digestivos, Servicio de Aparato Digestivo, Centro Médico Teknon, Barcelona, España. Electronic address: mearin@dr.teknon.es.
authors.forename: Fermín
authors.initials: F
authors.lastname: Mearin
authors.affiliation: Servicio de Aparato Digestivo, Hospital Clínico Universitario San Carlos, Madrid, España.
authors.forename: Enrique
authors.initials: E
authors.lastname: Rey
authors.affiliation: Instituto de Trastornos Funcionales y Motores Digestivos, Servicio de Aparato Digestivo, Centro Médico Teknon, Barcelona, España.
authors.forename: Agustín
authors.initials: A
authors.lastname: Balboa
mesh_terms: D003248:Constipation; D004415:Dyspepsia; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000628:therapy; D018589:Gastroparesis; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000175:diagnosis / Q000628:therapy
keywords: Acalasia; Achalasia; Criterios diagnósticos de Roma IV; Dispepsia funcional; Functional digestive disorders; Functional dispepsia; Gastroparesia; Gastroparesis; Irritable bowel syndrome; Rome IV diagnostic criteria; Síndrome del intestino irritable; Trastornos funcionales digestivos