title: Annual banned-substance review: analytical approaches in human sports drug testing.
abstract: There has been an immense amount of visibility of doping issues on the international stage over the past 12 months with the complexity of doping controls reiterated on various occasions. Hence, analytical test methods continuously being updated, expanded, and improved to provide specific, sensitive, and comprehensive test results in line with the World Anti-Doping Agency's (WADA) 2016 Prohibited List represent one of several critical cornerstones of doping controls. This enterprise necessitates expediting the (combined) exploitation of newly generated information on novel and/or superior target analytes for sports drug testing assays, drug elimination profiles, alternative test matrices, and recent advances in instrumental developments. This paper is a continuation of the series of annual banned-substance reviews appraising the literature published between October 2015 and September 2016 concerning human sports drug testing in the context of WADA's 2016 Prohibited List. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Center for Preventive Doping Research - Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany.|European Monitoring Center for Emerging Doping Agents, Cologne, Germany.
authors.forename: Mario
authors.initials: M
authors.lastname: Thevis
authors.affiliation: Swiss Laboratory for Doping Analyses, University Center of Legal Medicine, Genève and Lausanne, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Epalinges, Switzerland.
authors.forename: Tiia
authors.initials: T
authors.lastname: Kuuranne
authors.affiliation: Center for Preventive Doping Research - Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany.|European Monitoring Center for Emerging Doping Agents, Cologne, Germany.
authors.forename: Hans
authors.initials: H
authors.lastname: Geyer
authors.affiliation: Center for Preventive Doping Research - Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany.
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Schänzer
mesh_terms: D045930:Anabolic Agents / Q000032:analysis; D000697:Central Nervous System Stimulants / Q000032:analysis; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation / Q000379:methods*; D004232:Diuretics / Q000032:analysis; D004300:Doping in Sports / Q000379:methods; D005938:Glucocorticoids / Q000032:analysis; D006403:Hematologic Tests / Q000295:instrumentation / Q000379:methods; D006801:Humans; D009294:Narcotics / Q000032:analysis; D015813:Substance Abuse Detection / Q000295:instrumentation / Q000379:methods*; D016482:Urinalysis / Q000295:instrumentation / Q000379:methods
chemical_list: D045930:Anabolic Agents; D000697:Central Nervous System Stimulants; D004232:Diuretics; D005938:Glucocorticoids; D009294:Narcotics
keywords: doping; mass spectrometry; meldonium; sport