title: Human papillomavirus prevalence and associated factors in women and men in south China: a population-based study.
abstract: Oncogenic human papillomavirus (HPV) infection is a cause of many anogenital cancers in women and men; however, there is little research on HPV prevalence and risk factors that includes both women and men from the same population. A total of 4687 participants, including 2378 women and 2309 men aged 18-55 years old from the same community, were enrolled in the study in Liuzhou, China. Exfoliated cells were collected from the participants from different anatomic sites and were tested for 13 oncogenic and 3 non-oncogenic HPV types. The prevalence of any oncogenic HPV type was higher in women than in men (18.7% vs 9.4%, P<0.001), whereas the prevalence of HPV 6 and 11 infection was similar (1.4% vs 1.2%, P=0.6832). HPV 52, 58, 16, 39 and 18 were the five most prevalent types in both sexes. Sexual and hygienic behaviors were associated with HPV infection in both women and men. We found that oncogenic HPV DNA detection is more prevalent in women than in men in China, whereas the prevalence of HPV 6 and 11 is similar in both sexes. The data indicate that the interaction of host and virus might be different among high- and low-risk HPV types.
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Feixue
authors.initials: F
authors.lastname: Wei
authors.affiliation: Liuzhou Center for Disease Control and Prevention, Liuzhou 545027, Guangxi, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Yin
authors.affiliation: Liuzhou Center for Disease Control and Prevention, Liuzhou 545027, Guangxi, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wu
authors.affiliation: Liuzhou Center for Disease Control and Prevention, Liuzhou 545027, Guangxi, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Lan
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Shoujie
authors.initials: S
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Sheng
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Yingying
authors.initials: Y
authors.lastname: Su
authors.affiliation: Policy Coordination Division, China National Center for Biotechnology Development, Beijing 100039, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Centre for Vaccine Clinical Research, Guangxi Center for Disease Control and Prevention, Nanning 530028, Guangxi, China.
authors.forename: Yanping
authors.initials: Y
authors.lastname: Li
authors.affiliation: Centre for Vaccine Clinical Research, Guangxi Center for Disease Control and Prevention, Nanning 530028, Guangxi, China.
authors.forename: Rongcheng
authors.initials: R
authors.lastname: Li
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Liuzhou Center for Disease Control and Prevention, Liuzhou 545027, Guangxi, China.
authors.forename: Mingqiang
authors.initials: M
authors.lastname: Li
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Strait Collaborative Innovation Center of Biomedicine and Pharmaceutics, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.
authors.forename: Ningshao
authors.initials: N
authors.lastname: Xia
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D027383:Papillomaviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology*; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D055815:Young Adult