title: Solitary tentorial sarcoid granuloma associated with Propionibacterium acnes infection: case report.
abstract: Sarcoidosis is a systemic granulomatous disease with unknown cause, which very rarely occurs exclusively in the central nervous system. The authors performed biopsy sampling of a mass that developed in the left tentorium cerebelli that appeared to be a malignant tumor. The mass was diagnosed as a sarcoid granuloma, which was confirmed with the onset of antibody reaction product against Propionibacterium acnes. Findings suggesting sarcoidosis to be an immune response to P. acnes infection have recently been reported, and they give insight for diagnosis and treatment of this disease. The authors report the possible first case that was confirmed with P. acnes infection in a meningeal lesion in solitary neurosarcoidosis.
authors.affiliation: Department of Neurosurgery, Tokyo Medical University; and.
authors.forename: Jiro
authors.initials: J
authors.lastname: Akimoto
authors.affiliation: Department of Neurosurgery, Tokyo Medical University; and.
authors.forename: Kenta
authors.initials: K
authors.lastname: Nagai
authors.affiliation: Department of Neurosurgery, Tokyo Medical University; and.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ogasawara
authors.affiliation: Department of Neurosurgery, Tokyo Medical University; and.
authors.forename: Yujiro
authors.initials: Y
authors.lastname: Tanaka
authors.affiliation: Department of Neurosurgery, Tokyo Medical University; and.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Izawa
authors.affiliation: Department of Neurosurgery, Tokyo Medical University; and.
authors.forename: Michihiro
authors.initials: M
authors.lastname: Kohno
authors.affiliation: Department of Human Pathology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Uchida
authors.affiliation: Department of Human Pathology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Eishi
mesh_terms: D002493:Central Nervous System Diseases / Q000382:microbiology*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000150:complications*; D006099:Granuloma / Q000382:microbiology*; D006801:Humans; D008875:Middle Aged; D011425:Propionibacterium acnes; D012507:Sarcoidosis / Q000382:microbiology*; D013118:Spinal Cord Diseases / Q000382:microbiology*
keywords: MRI; PCR = polymerase chain reaction; Propionibacterium acnes infection; cerebellar tentorium; sarcoid granuloma