title: Should Prophylactic Anticoagulation Be Considered with Large Uterine Leiomyoma? A Case Series and Literature Review.
abstract: Introduction. Uterine leiomyomas, also called uterine fibroids or myomas, are the most common pelvic tumors in women. They are very rarely the cause of acute complications. However, when complications occur they cause significant morbidity and mortality. Thromboembolic disease has been described as a rare complication of uterine leiomyomas. DVT is a serious illness, sometimes causing death due to acute PE.Cases. We report a case series of 3 patients with thromboembolic disease associated with uterine leiomyoma at Hurley Medical Center, Flint, Michigan, during 2015 and conduct a literature review on the topic. A literature search was conducted using Medline, PubMed, and PMC databases from 1966 to 2015.Conclusion. The uterine leiomyoma is a very rare cause of PE and only few cases have been reported. DVT secondary to uterine leiomyoma should be considered in a female presenting with abdominal mass and pelvic pressure, if there is no clear common cause for her symptoms. Thromboembolic disease secondary to large uterine leiomyoma should be treated with acute stabilization and then hysterectomy. Prophylactic anticoagulation would be beneficial for lowering the risk of VTE in patients with large uterine leiomyoma.
authors.affiliation: Department of Obstetrics and Gynecology, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: Mohamed A
authors.identifier: 0000-0002-4641-6277
authors.initials: MA
authors.lastname: Satti
authors.affiliation: Department of Obstetrics and Gynecology, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: Carmen
authors.initials: C
authors.lastname: Paredes Saenz
authors.affiliation: Department of Obstetrics and Gynecology, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: Rubin
authors.initials: R
authors.lastname: Raju
authors.affiliation: Department of Obstetrics and Gynecology, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: Sierra
authors.initials: S
authors.lastname: Cuthpert
authors.affiliation: Department of Internal Medicine, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: Abed
authors.initials: A
authors.lastname: Kanzy
authors.affiliation: Department of Obstetrics and Gynecology, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: Sina
authors.initials: S
authors.lastname: Abhari
authors.affiliation: Department of Obstetrics and Gynecology, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: John
authors.initials: J
authors.lastname: Hebert Iii
authors.affiliation: Department of Obstetrics and Gynecology, Hurley Medical Center/Michigan State University College of Human Medicine, Flint, MI 48503, USA.
authors.forename: Frederico G
authors.initials: FG
authors.lastname: Rocha