title: Sequence Segmentation with changeptGUI.
abstract: Many biological sequences have a segmental structure that can provide valuable clues to their content, structure, and function. The program changept is a tool for investigating the segmental structure of a sequence, and can also be applied to multiple sequences in parallel to identify a common segmental structure, thus providing a method for integrating multiple data types to identify functional elements in genomes. In the previous edition of this book, a command line interface for changept is described. Here we present a graphical user interface for this package, called changeptGUI. This interface also includes tools for pre- and post-processing of data and results to facilitate investigation of the number and characteristics of segment classes.
authors.affiliation: School of Mathematical Sciences, Monash University, Clayton Campus, VIC, 3800, Australia.
authors.forename: Edward
authors.initials: E
authors.lastname: Tasker
authors.affiliation: School of Mathematical Sciences, Monash University, Clayton Campus, VIC, 3800, Australia. jonathan.keith@monash.edu.
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Keith
mesh_terms: D019295:Computational Biology / Q000379:methods*; D016678:Genome / Q000235:genetics; D012984:Software; D014584:User-Computer Interface
keywords: Functional element discovery; Genome segmentation; Model selection; Multiple change-point analysis