title: Trends in published meta-analyses in cancer research, 2008-2013.
abstract: In order to capture trends in the contribution of epidemiology to cancer research, we describe an online meta-analysis database resource for cancer clinical and population research and illustrate trends and descriptive detail of cancer meta-analyses from 2008 through 2013. A total of 4,686 cancer meta-analyses met our inclusion criteria. During this 6-year period, a fivefold increase was observed in the yearly number of meta-analyses. Fifty-six percent of meta-analyses concerned observational studies, mostly of cancer risk, more than half of which were genetic studies. The major cancer sites were breast, colorectal, and digestive. This online database for Cancer Genomics and Epidemiology Navigator will be continuously updated to allow investigators to quickly navigate the meta-analyses emerging from cancer epidemiology studies and cancer clinical trials.
authors.affiliation: Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, 6100 Executive Boulevard, Suite 2B03, Bethesda, MD, USA.
authors.forename: Ximena V
authors.initials: XV
authors.lastname: Qadir
authors.affiliation: Kelly Government Services, Troy, MI, USA.
authors.forename: Mindy
authors.initials: M
authors.lastname: Clyne
authors.affiliation: Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, 6100 Executive Boulevard, Suite 2B03, Bethesda, MD, USA.
authors.forename: Tram Kim
authors.initials: TK
authors.lastname: Lam
authors.affiliation: Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, 6100 Executive Boulevard, Suite 2B03, Bethesda, MD, USA.|Office of Public Health Genomics, Centers of Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Muin J
authors.initials: MJ
authors.lastname: Khoury
authors.affiliation: Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, 6100 Executive Boulevard, Suite 2B03, Bethesda, MD, USA. schullys@mail.nih.gov.|Office of Disease Prevention, National Institutes of Health, Bethesda, MD, USA. schullys@mail.nih.gov.
authors.forename: Sheri D
authors.initials: SD
authors.lastname: Schully
mesh_terms: D006801:Humans; D015201:Meta-Analysis as Topic; D009369:Neoplasms; D011643:Publishing / Q000639:trends*; D012106:Research
keywords: Clinical trials; Database; Epidemiology; Meta-analysis