title: Comparative analysis of common regions found in babuviruses and alphasatellite molecules.
abstract: Viruses in the genus Babuvirus have multi-component ssDNA genomes and often associate with alphasatellite molecules containing two common motifs, a common-region stem-loop (CR-SL) involved in initiation of rolling-circle replication and a common-region major (CR-M) motif involved in secondary-strand synthesis. We compared known babuvirus genome components and alphasatellite CR-SL and CR-M sequences, defining five divergent CR-SL sequence classes. We identified iterated sequence elements in babuvirus genome components that have particularly conserved sequences and spatial arrangements between known babuviruses.
authors.affiliation: School of Biological Sciences, University of Canterbury, Christchurch, 8140, New Zealand.
authors.forename: Daisy
authors.initials: D
authors.lastname: Stainton
authors.affiliation: Department of Clinical Laboratory Sciences, University of Cape Town, Cape Town, South Africa.
authors.forename: Darren P
authors.initials: DP
authors.lastname: Martin
authors.affiliation: School of Biological Sciences, University of Canterbury, Christchurch, 8140, New Zealand.|School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, 2308, Australia.
authors.forename: David A
authors.initials: DA
authors.lastname: Collings
authors.affiliation: School of Biological Sciences, University of Canterbury, Christchurch, 8140, New Zealand. arvind.varsani@asu.edu.|Department of Clinical Laboratory Sciences, University of Cape Town, Cape Town, South Africa. arvind.varsani@asu.edu.|The Biodesign Center for Fundamental and Applied Microbiomics, and School of Life Sciences, Arizona State University, Tempe, AZ, 85287-5001, USA. arvind.varsani@asu.edu.
authors.forename: Arvind
authors.identifier: http://orcid.org/0000-0003-4111-2415
authors.initials: A
authors.lastname: Varsani
mesh_terms: D052658:Babuvirus / Q000235:genetics*; D001483:Base Sequence; D017124:Conserved Sequence; D004276:DNA, Satellite / Q000235:genetics*; D004277:DNA, Single-Stranded / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics*; D016679:Genome, Viral; D008969:Molecular Sequence Data
chemical_list: D004276:DNA, Satellite; D004277:DNA, Single-Stranded; D004279:DNA, Viral