title: Measurement of Behavioral Taste Responses in Mice: Two-Bottle Preference, Lickometer, and Conditioned Taste-Aversion Tests.
abstract: The natural like and dislike of foods based on taste is one of the most easily observed behaviors in animals. Animals eat palatable foods and reject aversive foods, which makes measurement of taste perception possible using various behavioral techniques. Three different methods to accurately measure taste behavior are described here. First, two-bottle preference tests evaluate whether a taste compound (tastant) is preferred over water. Second, lickometer tests quantify the like and dislike for multiple concentrations of the same tastant or multiple tastants at the same time. Finally, conditioned taste aversion tests accurately determine the perceived taste threshold for palatable tastants. Together, these diverse methods enable researchers to observe and measure behavioral taste responses in mice to any tastant. © 2016 by John Wiley & Sons, Inc.
authors.affiliation: Department of Cell and Developmental Biology and the Rocky Mountain Taste and Smell Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
authors.forename: Dany
authors.initials: D
authors.lastname: Gaillard
authors.affiliation: Department of Cell and Developmental Biology and the Rocky Mountain Taste and Smell Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Stratford
mesh_terms: D000818:Animals; D001362:Avoidance Learning; D001681:Biological Assay / Q000295:instrumentation / Q000379:methods*; D003214:Conditioning, Classical; D005518:Food Preferences; D051379:Mice; D013649:Taste; D055697:Taste Perception
keywords: conditioned taste aversion; lickometer; taste behavior; taste discrimination; taste threshold; two-bottle preference test