title: Accuracy of contrast-enhanced ultrasound compared with conventional ultrasound in acute pancreatitis: Diagnosis and complication monitoring.
abstract: Contrast-enhanced ultrasound (CEUS) has been used for diagnosing acute pancreatitis (AP), particularly severe acute pancreatitis (SAP). However, the diagnostic difference between CEUS and conventional ultrasonography (CUS) for AP and SAP has not been reported. The aim of the present study was to investigate the diagnostic accuracy of CUS and CEUS for AP. A total of 196 patients clinically diagnosed with AP were selected. All patients underwent CUS, CEUS and contrast-enhanced computed tomography (CECT) within 72 h. CECT was considered the gold standard. Pancreatic size, peripancreatic fluid collection (PPFC) and splenic vessel complications were the variables observed by CUS and CEUS. The differences in the variables among the three methods were analyzed using the χ2test and statistical analysis software. Significant differences in pancreatic size, PPFC and splenic vessel complications in AP were observed between CEUS and CUS (P<0.05). χ2test results indicated that CEUS significantly differed from CUS in terms of having a higher diagnostic accuracy for AP and SAP (P<0.05). The results indicate that CEUS is a reliable method for the diagnosis and monitoring of AP and SAP, and may be substituted for CECT.
authors.affiliation: Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Diming
authors.initials: D
authors.lastname: Cai
authors.affiliation: Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Shyam Sundar
authors.initials: SS
authors.lastname: Parajuly
authors.affiliation: Training Department of Resident Doctor, West China School of Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Huiyao
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Operations Management, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Wenwu
authors.initials: W
authors.lastname: Ling
authors.affiliation: Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Song
authors.affiliation: Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Yongzhong
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Luo
keywords: acute pancreatitis; contrast-enhanced ultrasound; conventional ultrasound; diagnosis; peripancreatic fluid collection; severe acute pancreatitis; splenic vessel complications