title: TFEB and TFE3: The art of multi-tasking under stress conditions.
abstract: Cellular adaptation response to a myriad of stressors is key for survival. The lysosomal/autophagy pathway is inextricably connected to the stress response regulation. Two transcription factors, TFEB and TFE3, have recently emerged as master regulators of this degradative pathway. Their function modulating different cellular pathways will be discussed.
authors.affiliation: a Cell Biology and Physiology Center , National Heart, Lung, and Blood Institute, National Institutes of Health , Bethesda , MD , USA.
authors.forename: José A
authors.initials: JA
authors.lastname: Martina
authors.affiliation: a Cell Biology and Physiology Center , National Heart, Lung, and Blood Institute, National Institutes of Health , Bethesda , MD , USA.
authors.forename: Rosa
authors.initials: R
authors.lastname: Puertollano
mesh_terms: D001343:Autophagy; D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / Q000378:metabolism*; D005786:Gene Expression Regulation; D006801:Humans; D008247:Lysosomes / Q000378:metabolism; D015398:Signal Transduction; D013312:Stress, Physiological
chemical_list: D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; C069203:TFE3 protein, human; C064972:TFEB protein, human
keywords: TFE3; TFEB; autophagy; lysosomes; stress