title: The neXtProt knowledgebase on human proteins: 2017 update.
abstract: The neXtProt human protein knowledgebase (https://www.nextprot.org) continues to add new content and tools, with a focus on proteomics and genetic variation data. neXtProt now has proteomics data for over 85% of the human proteins, as well as new tools tailored to the proteomics community.Moreover, the neXtProt release 2016-08-25 includes over 8000 phenotypic observations for over 4000 variations in a number of genes involved in hereditary cancers and channelopathies. These changes are presented in the current neXtProt update. All of the neXtProt data are available via our user interface and FTP site. We also provide an API access and a SPARQL endpoint for more technical applications.
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206 pascale.gaudet@sib.swiss.|Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1206.
authors.forename: Pascale
authors.identifier: 0000-0003-1813-6857
authors.initials: P
authors.lastname: Gaudet
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Pierre-André
authors.initials: PA
authors.lastname: Michel
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Monique
authors.initials: M
authors.lastname: Zahn-Zabal
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Aurore
authors.initials: A
authors.lastname: Britan
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Cusin
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.|Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1206.
authors.forename: Marcin
authors.initials: M
authors.lastname: Domagalski
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Paula D
authors.initials: PD
authors.lastname: Duek
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Alain
authors.initials: A
authors.lastname: Gateau
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Anne
authors.initials: A
authors.lastname: Gleizes
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Valérie
authors.initials: V
authors.lastname: Hinard
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.|Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1206.
authors.forename: Valentine
authors.initials: V
authors.lastname: Rech de Laval
authors.affiliation: Sun Yat-sen University, 135 Xingang W Rd, Haizhu, Guangzhou, Guangdong, China.
authors.forename: JinJin
authors.initials: J
authors.lastname: Lin
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Frederic
authors.initials: F
authors.lastname: Nikitin
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.|Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1206.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Schaeffer
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.
authors.forename: Daniel
authors.initials: D
authors.lastname: Teixeira
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.|Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1206.
authors.forename: Lydie
authors.initials: L
authors.lastname: Lane
authors.affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1206.|Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1206.
authors.forename: Amos
authors.initials: A
authors.lastname: Bairoch
mesh_terms: D030562:Databases, Protein; D056726:Genetic Association Studies; D014644:Genetic Variation; D006801:Humans; D020407:Internet; D010641:Phenotype; D040901:Proteomics / Q000379:methods; D012984:Software; D064878:Web Browser