title: Corrosion resistance and biological activity of TiO2implant coatings produced in oxygen-rich environments.
abstract: The physical and chemical properties of bio-titanium alloy implant surfaces play an important role in their corrosion resistance and biological activity. New turning and turning-rolling processes are presented, employing an oxygen-rich environment in order to obtain titanium dioxide layers that can both protect implants from corrosion and also promote cell adhesion. The surface topographies, surface roughnesses and chemical compositions of the sample surfaces were obtained using scanning electron microscopy, a white light interferometer, and the Auger electron spectroscopy, respectively. The corrosion resistance of the samples in a simulated body fluid was determined using electrochemical testing. Biological activity on the samples was also analyzed, using a vitro cell culture system. The results show that compared with titanium oxide layers formed using a turning process in air, the thickness of the titanium oxide layers formed using turning and turning-rolling processes in an oxygen-rich environment increased by 4.6 and 7.3 times, respectively. Using an oxygen-rich atmosphere in the rolling process greatly improves the corrosion resistance of the resulting samples in a simulated body fluid. On samples produced using the turning-rolling process, cells spread quickly and exhibited the best adhesion characteristics.
authors.affiliation: 1 Key Laboratory of High Efficiency and Clean Manufacturing, School of Mechanical Engineering, Shandong University, Jinan, People's Republic of China.|2 College of Transportation, Ludong University, Yantai, People's Republic of China.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.affiliation: 1 Key Laboratory of High Efficiency and Clean Manufacturing, School of Mechanical Engineering, Shandong University, Jinan, People's Republic of China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wan
authors.affiliation: 1 Key Laboratory of High Efficiency and Clean Manufacturing, School of Mechanical Engineering, Shandong University, Jinan, People's Republic of China.
authors.forename: Xing
authors.initials: X
authors.lastname: Ai
authors.affiliation: 1 Key Laboratory of High Efficiency and Clean Manufacturing, School of Mechanical Engineering, Shandong University, Jinan, People's Republic of China.
authors.forename: Zhanqiang
authors.initials: Z
authors.lastname: Liu
authors.affiliation: 3 Qilu Hospital, Shandong University, Jinan, People's Republic of China.
authors.forename: Dong
authors.initials: D
authors.lastname: Zhang
mesh_terms: D016475:3T3 Cells; D000818:Animals; D001696:Biomechanical Phenomena; D002448:Cell Adhesion; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D003343:Corrosion; D006801:Humans; D008422:Materials Testing / Q000295:instrumentation; D051379:Mice; D008855:Microscopy, Electron, Scanning; D010006:Osteoblasts / Q000166:cytology; D010100:Oxygen; D019736:Prostheses and Implants; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry
chemical_list: D020099:Coated Materials, Biocompatible; C009495:titanium dioxide; D014025:Titanium; D010100:Oxygen
keywords: Titanium dioxide layer; biological activity; corrosion resistance; oxygen-rich environment; rolling; turning