title: Characterization of GlobalFiler loci in Angolan and Guinean populations inhabiting Southern Portugal.
abstract: We analyzed the GlobalFiler short tandem repeat (STR) loci for 152 and 70 unrelated individuals from Angolan and Guinean immigrant populations inhabiting Southern Portugal, respectively. After Bonferroni correction, no significant deviations from the Hardy-Weinberg equilibrium and linkage disequilibrium were detected for either population. For the Angolan population, SE33 was the most informative marker. In contrast, D5S818 and D13S317 were the least informative loci. The combined power of discrimination was 99.9999999999999999999999961907%. For the Guinean population, SE33 and D21S1 were the most informative loci, while D13S317 was the least. The combined power of discrimination was 99.99999999999999999999997915%. No significant differences were observed between Angolan, Guinean, and Afro-American populations for any of the analyzed STRs. The South African population presented significant differences at D22S1045 and D10S1248 when compared to Angola, and at D22S1045 when compared to Guinea-Bissau. The MDS plot and neighbor-joining tree analysis revealed that Angolan and Guinean populations are genetically close to African-American and South African populations, and genetically different from Korean, Mexican, European (including American-Caucasian), and Middle Eastern populations.
authors.affiliation: INMLCF-National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213, Coimbra, Portugal.|Biomedical Sciences Institute, Porto University, Rua de Jorge Viterbo Ferreira n.º 228, 4050-313, Porto, Portugal.
authors.forename: Soraia
authors.initials: S
authors.lastname: Guerreiro
authors.affiliation: INMLCF-National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213, Coimbra, Portugal.|CENCIFOR-Forensic Sciences Centre, Largo da Sé Nova, s/n, 3000-213, Coimbra, Portugal.
authors.forename: Teresa
authors.initials: T
authors.lastname: Ribeiro
authors.affiliation: INMLCF-National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213, Coimbra, Portugal.|CENCIFOR-Forensic Sciences Centre, Largo da Sé Nova, s/n, 3000-213, Coimbra, Portugal.
authors.forename: Maria João
authors.initials: MJ
authors.lastname: Porto
authors.affiliation: Biomedical Sciences Institute, Porto University, Rua de Jorge Viterbo Ferreira n.º 228, 4050-313, Porto, Portugal.
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Carneiro de Sousa
authors.affiliation: INMLCF-National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213, Coimbra, Portugal. paulo.a.dario@inmlcf.mj.pt.|CENCIFOR-Forensic Sciences Centre, Largo da Sé Nova, s/n, 3000-213, Coimbra, Portugal. paulo.a.dario@inmlcf.mj.pt.|Faculty of Sciences, University of Lisbon, Campo Grande, 1749-016, Lisbon, Portugal. paulo.a.dario@inmlcf.mj.pt.|CESAM-Centre for Environmental and Marine Studies, Pólo de Lisboa, Edifício C2, Campo Grande, 1749-016, Lisbon, Portugal. paulo.a.dario@inmlcf.mj.pt.
authors.forename: Paulo
authors.identifier: http://orcid.org/0000-0002-4203-9179
authors.initials: P
authors.lastname: Dario
mesh_terms: D016172:DNA Fingerprinting; D054242:Emigrants and Immigrants; D005006:Ethnicity / Q000235:genetics; D005787:Gene Frequency; D056426:Genetic Loci; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction / Q000295:instrumentation*; D011174:Portugal; D044469:Racial Groups / Q000235:genetics
keywords: Angola; GlobalFiler™ PCR Amplification Kit; Guinea-Bissau; Population genetics