title: Synthesis of Monoalkyl Glyceryl Ethers by Ring Opening of Glycidol with Alcohols in the Presence of Lewis Acids.
abstract: The present work deals with the production of monoalkyl glyceryl ethers (MAGEs) through a new reaction pathway based on the reaction of glycidol and alcohols catalyzed by Lewis acid-based catalysts. Glycidol is quantitatively converted with high selectivity (99 %) into MAGEs under very mild reaction conditions (80 °C and 0.01 mol % catalyst loading) in only 1 h using Al(OTf)3or Bi(OTf)3as catalyst. The proposed method enhances the choice of possible green synthetic approaches for the production of value-added products such as MAGEs.
authors.affiliation: Department of Chemistry and Biology "Adolfo Zambelli", University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano (SA), Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Cucciniello
authors.affiliation: Department of Chemistry and Biology "Adolfo Zambelli", University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano (SA), Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Ricciardi
authors.affiliation: Department of Chemical Sciences, University of Naples "Federico II", Via Cinthia 4, 80126, Naples, Italy.
authors.forename: Rosa
authors.initials: R
authors.lastname: Vitiello
authors.affiliation: Department of Chemical Sciences, University of Naples "Federico II", Via Cinthia 4, 80126, Naples, Italy.
authors.forename: Martino
authors.initials: M
authors.lastname: Di Serio
authors.affiliation: Department of Chemistry and Biology "Adolfo Zambelli", University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano (SA), Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Proto
authors.affiliation: Department of Chemistry and Biology "Adolfo Zambelli", University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano (SA), Italy.
authors.forename: Carmine
authors.identifier: http://orcid.org/0000-0001-7254-8620
authors.initials: C
authors.lastname: Capacchione
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry*; D005995:Glyceryl Ethers / Q000138:chemical synthesis*; D055772:Green Chemistry Technology; D058116:Lewis Acids / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*
chemical_list: D000438:Alcohols; D004852:Epoxy Compounds; D005995:Glyceryl Ethers; D058116:Lewis Acids; D020005:Propanols; C004312:glycidol
keywords: Lewis acids; ethers; glycerol; green chemistry; waste valorization