title: Update on Crystal-Induced Arthritides.
abstract: The prevalence of gout increases with age. Once serum concentration of urate exceeds the saturation/solubility point, it deposits in and around the joints. Clinical presentation in the elderly often has "atypical" features and is challenging to diagnose. Treatment depends on the stage of the disease and the patient's health status and comorbidities. Elderly patients often have several confounding issues; thus, treatment decisions can be complicated and therapeutic options limited. To prevent the recurrence of gout attacks, serum concentration of urate should be maintained well below the saturation threshold of 6.8 mg/dL, leading to dissolution of urate deposits and prevent recurrence.
authors.affiliation: Charles E. Schmidt College of Medicine, Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431, USA; Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL 33331, USA. Electronic address: elzawah@ccf.org.
authors.forename: Hossam
authors.initials: H
authors.lastname: El-Zawawy
authors.affiliation: Department of Rheumatic and Immunologic Disease, Cleveland Clinic Lerner College of Medicine, 9500 Euclid Avenue, A50, Cleveland, OH 44195, USA.
authors.forename: Brian F
authors.initials: BF
authors.lastname: Mandell
mesh_terms: D000368:Aged; D014943:Global Health; D006073:Gout / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D009017:Morbidity; D015995:Prevalence; D014527:Uric Acid / Q000097:blood*
chemical_list: D014527:Uric Acid
keywords: Comorbidities; Geriatrics; Gout; Treat to target