title: Case Study: An intraoperative finding of black bone disease in a podiatric surgery patient.
abstract: Black bone disease has been recognised as a potential consequence of long-term treatment with tetracycline antibiotics. Largely documented affecting structures in the head and skull, there are few reported cases of black bone disease in the foot and ankle. The case of a 55 years old patient, who as a teenager, had undergone treatment with minocycline hydrochloride for chronic acne, and was found to have bone discolouration consistent with minocycline induced black bone disease (MIBBD) during the course of hallux valgus corrective surgery some 40 years later, is presented. In spite of the intraoperative findings, the patient's post-operative recovery and bone healing was uneventful. The literature on minocycline induced black bone disease is reviewed.
authors.affiliation: Department of Podiatric Surgery, Homerton University Hospital NHS Foundation Trust, Homerton Row, London, E9 6SR, United Kingdom. Electronic address: rcarterwale@gmail.com.
authors.forename: Robyn L
authors.initials: RL
authors.lastname: Carter-Wale
authors.affiliation: Department of Podiatric Surgery, Homerton University Hospital NHS Foundation Trust, Homerton Row, London, E9 6SR, United Kingdom.
authors.forename: Trevor D
authors.initials: TD
authors.lastname: Prior
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001847:Bone Diseases / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006215:Hallux Valgus / Q000601:surgery; D006801:Humans; D007432:Intraoperative Period; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline
keywords: Black bone disease; Foot; Hallux valgus; Minocycline hydrochloride; Podiatric surgery; Tetracyclines