title: Severe pelvic injury: vascular lesions detected by ante- and post-mortem contrast medium-enhanced CT and associations with pelvic fractures.
abstract: OBJECTIVE
  The objectives of this study were to compare arterial and venous contrast medium extravasation in severe pelvic injury detected by ante- and post-mortem multi-detector CT (MDCT) and determine whether vascular injury is associated with certain types of pelvic fracture.
  
  
  METHODS
  We retrospectively included two different cohorts of blunt pelvic trauma with contrast medium extravasation shown by MDCT. The first group comprised 49 polytrauma patients; the second included 45 dead bodies undergoing multi-phase post-mortem CT-angiography (MPMCTA). Two radiologists jointly reviewed each examination concerning type, site of bleeding and pattern of underlying pelvic ring fracture.
  
  
  RESULTS
  All 49 polytrauma patients demonstrated arterial bleeding, immediately undergoing subsequent angiography; 42 (85%) had pelvic fractures, but no venous bleeding was disclosed. MPMCTA of 45 bodies revealed arterial (n = 33, 73%) and venous (n = 35, 78%) bleeding and pelvic fractures (n = 41, 91%). Pelvic fracture locations were significantly correlated with ten arterial and six venous bleeding sites in dead bodies, with five arterial bleeding sites in polytrauma patients. In dead bodies, arterial haemorrhage was significantly correlated with the severity of pelvic fracture according to Tile classification (p = 0.01), unlike venous bleeding (p = 0.34).
  
  
  CONCLUSIONS
  In severe pelvic injury, certain acute bleeding sites were significantly correlated with underlying pelvic fracture locations. MPMCTA revealed more venous lesions than MDCT in polytrauma patients. Future investigations should evaluate the proportional contribution of venous bleeding to overall pelvic haemorrhage as well as its clinical significance.
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland. mahmoud.hussami@chuv.ch.
authors.forename: Mahmoud
authors.identifier: http://orcid.org/0000-0002-1846-4271
authors.initials: M
authors.lastname: Hussami
authors.affiliation: University Center of Legal Medicine Lausanne-Geneva, University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
authors.forename: Silke
authors.initials: S
authors.lastname: Grabherr
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
authors.forename: Reto A
authors.initials: RA
authors.lastname: Meuli
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
authors.forename: Sabine
authors.initials: S
authors.lastname: Schmidt
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D001158:Arteries / Q000293:injuries*; D003287:Contrast Media; D005260:Female; D050723:Fractures, Bone / Q000000981:diagnostic imaging*; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D010384:Pelvic Bones / Q000000981:diagnostic imaging* / Q000293:injuries; D010690:Phlebography; D012189:Retrospective Studies; D014680:Veins / Q000293:injuries*; D055815:Young Adult
chemical_list: D003287:Contrast Media
keywords: Forensic radiology; Multi-detector computed tomography (MDCT); Multi-phase post-mortem CT-angiography (MPMCTA); Pelvic bone fractures; Pelvic fracture bleeding; Vascular system injuries