title: Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters.
abstract: OBJECTIVE
  To investigate sexuality and depression in women with FM compared with controls and to correlate the findings with hematological parameters.
  
  
  METHODS
  33 women with FM and 19 healthy women were included and evaluated with the following instruments: Female Sexual Function Index, Beck Inventory, Visual Analogue Scale, medical history and laboratory exams.
  
  
  RESULTS
  The prevalence of sexual dysfunction (P = 0.007) and depression (P < 0.001) were higher in the study group than in the control group; they were positively correlated (P = 0.023). The study group showed lower serum concentrations of testosterone, free T4, antinuclear factor, and lower blood hemoglobin and hematocrit.
  
  
  CONCLUSIONS
  FM was associated with high scores of sexual dysfunction and depression, and there were correlations with hematological parameters. We suggest the involvement of immune-inflammatory mediators and FM, which need further investigation to understand their role in FM syndrome and its comorbidities.
authors.affiliation: Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, São Paulo SP, Brasil.|Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil.
authors.forename: Bruna
authors.initials: B
authors.lastname: Alves
authors.affiliation: Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil.
authors.forename: Telma M
authors.initials: TM
authors.lastname: Zakka
authors.affiliation: Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil.
authors.forename: Manoel J
authors.initials: MJ
authors.lastname: Teixeira
authors.affiliation: Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil.
authors.forename: Helena H
authors.initials: HH
authors.lastname: Kaziyama
authors.affiliation: Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Grupo de Dor Orofacial, São Paulo SP, Brasil.
authors.forename: Jose T T
authors.initials: JT
authors.lastname: Siqueira
authors.affiliation: Universidade de São Paulo, Escola de Artes, Ciências e Humanidades, São Paulo SP, Brasil.|Universidade de São Paulo, Faculdade de Medicina, Centro Interdisciplinar de Dor, Departamento de Neurologia, São Paulo SP, Brasil.
authors.forename: Silvia R D T
authors.initials: SR
authors.lastname: Siqueira
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D003863:Depression / Q000150:complications*; D005260:Female; D005356:Fibromyalgia / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008875:Middle Aged; D012735:Sexual Dysfunction, Physiological / Q000150:complications*; D020018:Sexual Dysfunctions, Psychological / Q000150:complications*; D011795:Surveys and Questionnaires; D013739:Testosterone / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D000974:Antibodies, Antinuclear; D006454:Hemoglobins; D013739:Testosterone; D013974:Thyroxine