title: Anal Dysplasia.
abstract: Anal dysplasia is a cytopathology term describing specific squamous cell morphology and represents a varying degree of benign changes. Often a source of confusion, the current iteration includes two types, low-grade and high-grade, and carries significant clinical implications. This article updates readers on the current definition of anal dysplasia, describes its incidence and prevalence, defines high-risk populations, and highlights diagnostics, treatment, and long-term management strategies for patients with anal dysplasia.
authors.affiliation: Section of Colon and Rectal Surgery, Surgical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA. Electronic address: Cmessick@mdanderson.org.
authors.forename: Craig A
authors.initials: CA
authors.lastname: Messick
authors.affiliation: Section of Colon and Rectal Surgery, Surgical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Rodriguez-Bigas
mesh_terms: D001005:Anus Neoplasms / Q000453:epidemiology / Q000473:pathology*; D002278:Carcinoma in Situ / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D015994:Incidence; D015995:Prevalence
keywords: Anal cytology; Anal dysplasia; HGAIN; HSIL; High-resolution anoscopy; LGAIN; LSIL; Squamous cell carcinoma