title: A 3D reconstruction algorithm for magneto-acoustic tomography with magnetic induction based on ultrasound transducer characteristics.
abstract: In this study we present a three-dimensional (3D) reconstruction algorithm for magneto-acoustic tomography with magnetic induction (MAT-MI) based on the characteristics of the ultrasound transducer. The algorithm is investigated to solve the blur problem of the MAT-MI acoustic source image, which is caused by the ultrasound transducer and the scanning geometry. First, we established a transducer model matrix using measured data from the real transducer. With reference to the S-L model used in the computed tomography algorithm, a 3D phantom model of electrical conductivity is set up. Both sphere scanning and cylinder scanning geometries are adopted in the computer simulation. Then, using finite element analysis, the distribution of the eddy current and the acoustic source as well as the acoustic pressure can be obtained with the transducer model matrix. Next, using singular value decomposition, the inverse transducer model matrix together with the reconstruction algorithm are worked out. The acoustic source and the conductivity images are reconstructed using the proposed algorithm. Comparisons between an ideal point transducer and the realistic transducer are made to evaluate the algorithms. Finally, an experiment is performed using a graphite phantom. We found that images of the acoustic source reconstructed using the proposed algorithm are a better match than those using the previous one, the correlation coefficient of sphere scanning geometry is 98.49% and that of cylinder scanning geometry is 94.96%. Comparison between the ideal point transducer and the realistic transducer shows that the correlation coefficients are 90.2% in sphere scanning geometry and 86.35% in cylinder scanning geometry. The reconstruction of the graphite phantom experiment also shows a higher resolution using the proposed algorithm. We conclude that the proposed reconstruction algorithm, which considers the characteristics of the transducer, can obviously improve the resolution of the reconstructed image. This study can be applied to analyse the effect of the position of the transducer and the scanning geometry on imaging. It may provide a more precise method to reconstruct the conductivity distribution in MAT-MI.
authors.affiliation: Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, People's Republic of China.
authors.forename: Ren
authors.initials: R
authors.lastname: Ma
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Zhou
authors.forename: Shunqi
authors.initials: S
authors.lastname: Zhang
authors.forename: Tao
authors.initials: T
authors.lastname: Yin
authors.forename: Zhipeng
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000465:Algorithms; D021621:Imaging, Three-Dimensional / Q000379:methods*; D060328:Magnetic Phenomena; D019047:Phantoms, Imaging; D014057:Tomography, X-Ray Computed; D014159:Transducers; D014465:Ultrasonics / Q000295:instrumentation*