title: Migraine: A disorder of metabolism?
abstract: The treatment and prevention of migraine within the last decade has become largely pharmacological. While there is little doubt that the advent of drugs (e.g. triptans) has helped many migraine sufferers to lead a normal life, there is still little knowledge with respect to the factors responsible for precipitating a migraine attack. Evidence from biochemical and behavioural studies from a number of disciplines is integrated to put forward the proposal that migraine is part of a cascade of events, which together act to protect the organism when confronted by a metabolic challenge.
authors.affiliation: University of New England, School of Health, Armidale, NSW 2350, United States. Electronic address: akokavec@une.edu.au.
authors.forename: Anna
authors.initials: A
authors.lastname: Kokavec
mesh_terms: D000818:Animals; D004435:Eating; D005215:Fasting; D005260:Female; D005502:Food; D005947:Glucose / Q000378:metabolism; D051274:Glucose Transporter Type 3 / Q000378:metabolism; D051275:Glucose Transporter Type 4 / Q000378:metabolism; D006632:Histamine / Q000378:metabolism; D006801:Humans; D007003:Hypoglycemia / Q000378:metabolism; D007333:Insulin Resistance; D007737:Kynurenine / Q000378:metabolism; D008297:Male; D008881:Migraine Disorders / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology*; D008962:Models, Theoretical; D014662:Vasoconstrictor Agents / Q000494:pharmacology
chemical_list: D051274:Glucose Transporter Type 3; D051275:Glucose Transporter Type 4; C495687:SLC2A3 protein, human; C495692:SLC2A4 protein, human; D014662:Vasoconstrictor Agents; D007737:Kynurenine; D006632:Histamine; D005947:Glucose
keywords: Glucose; Hypoglycemia; Insulin; Insulin resistance; Migraine; Nutrition