title: Uterine rupture in pregnancies following myomectomy: A multicenter case series.
abstract: OBJECTIVE
  The purpose of this case series was to retrospectively examine records of cases with uterine rupture in pregnancies following myomectomy and to describe the clinical features and pregnancy outcomes.
  
  
  METHODS
  This study was conducted as a multicenter case series. The patient databases at 7 tertiary hospitals were queried. Records of patients with a diagnosis of uterine rupture in the pregnancy following myomectomy between January 2012 and December 2014 were retrospectively collected. The uterine rupture cases enrolled in this study were defined as follows: through-and-through uterine rupture or tear of the uterine muscle and serosa, occurrence from 24+0 to 41+6 weeks' gestation, singleton pregnancy, and previous laparoscopic myomectomy (LSM) or laparotomic myomectomy (LTM) status.
  
  
  RESULTS
  Fourteen pregnant women experienced uterine rupture during their pregnancy after LSM or LTM. Preterm delivery of less than 34 weeks' gestation occurred in 5 cases, while intrauterine fetal death occurred in 3, and 3 cases had fetal distress. Of the 14 uterine rupture cases, none occurred during labor. All mothers survived and had no sequelae, unlike the perinatal outcomes, although they were receiving blood transfusion or treatment for uterine artery embolization because of uterine atony or massive hemorrhage.
  
  
  CONCLUSIONS
  In women of childbearing age who are scheduled to undergo LTM or LSM, the potential risk of uterine rupture on subsequent pregnancy should be explained before surgery. Pregnancy in women after myomectomy should be carefully observed, and they should be adequately counseled during this period.
authors.affiliation: Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Hee-Sun
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Soo-Young
authors.initials: SY
authors.lastname: Oh
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Suk-Joo
authors.initials: SJ
authors.lastname: Choi
authors.affiliation: Department of Obstetrics and Gynecology, Graduate School of Medicine, Dongguk University, Goyang, Korea.
authors.forename: Hyun-Soo
authors.initials: HS
authors.lastname: Park
authors.affiliation: Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
authors.forename: Geum-Joon
authors.initials: GJ
authors.lastname: Cho
authors.affiliation: Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Seoul, Korea.
authors.forename: Jin-Hoon
authors.initials: JH
authors.lastname: Chung
authors.affiliation: Department of Obstetrics and Gynecology, Eulji Hospital, Eulji University School of Medicine, Seoul, Korea.
authors.forename: Yong-Soo
authors.initials: YS
authors.lastname: Seo
authors.affiliation: Department of Obstetrics and Gynecology, Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea.
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Jung
authors.affiliation: Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Jung-Eun
authors.initials: JE
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Su-Hyun
authors.initials: SH
authors.lastname: Chae
authors.affiliation: Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Han-Sung
authors.identifier: 0000-0003-0622-0701
authors.initials: HS
authors.lastname: Hwang
keywords: Myomectomy; Pregnancy outcome; Uterine rupture