title: Prospects for Biological Soilborne Disease Control: Application of Indigenous Versus Synthetic Microbiomes.
abstract: Biological disease control of soilborne plant diseases has traditionally employed the biopesticide approach whereby single strains or strain mixtures are introduced into production systems through inundative/inoculative release. The approach has significant barriers that have long been recognized, including a generally limited spectrum of target pathogens for any given biocontrol agent and inadequate colonization of the host rhizosphere, which can plague progress in the utilization of this resource in commercial field-based crop production systems. Thus, although potential exists, this model has continued to lag in its application. New omics' tools have enabled more rapid screening of microbial populations allowing for the identification of strains with multiple functional attributes that may contribute to pathogen suppression. Similarly, these technologies also enable the characterization of consortia in natural systems which provide the framework for construction of synthetic microbiomes for disease control. Harnessing the potential of the microbiome indigenous to agricultural soils for disease suppression through application of specific management strategies has long been a goal of plant pathologists. Although this tactic also possesses limitation, our enhanced understanding of functional attributes of suppressive soil systems through application of community and metagenomic analysis methods provide opportunity to devise effective resource management schemes. As these microbial communities in large part are fostered by the resources endemic to soil and the rhizosphere, substrate mediated recruitment of disease-suppressive microbiomes constitutes a practical means to foster their establishment in crop production systems.
authors.affiliation: First author: U.S. Department of Agriculture-Agricultural Research Service, Physiology and Pathology of Tree Fruits Research Laboratory, 1104 N. Western Avenue, Wenatchee, WA 98801; and second author: Agricultural Research Organization of Israel, Volcani Center, Bet Dagan, Israel.
authors.forename: Mark
authors.initials: M
authors.lastname: Mazzola
authors.affiliation: First author: U.S. Department of Agriculture-Agricultural Research Service, Physiology and Pathology of Tree Fruits Research Laboratory, 1104 N. Western Avenue, Wenatchee, WA 98801; and second author: Agricultural Research Organization of Israel, Volcani Center, Bet Dagan, Israel.
authors.forename: Shiri
authors.initials: S
authors.lastname: Freilich
mesh_terms: D000383:Agriculture; D061046:Biological Control Agents; D064307:Microbiota; D010572:Pest Control, Biological / Q000379:methods*; D010935:Plant Diseases / Q000382:microbiology / Q000517:prevention & control*; D058441:Rhizosphere; D012987:Soil; D012988:Soil Microbiology
chemical_list: D061046:Biological Control Agents; D012987:Soil