title: Carbon-Based Materials for Photo-Triggered Theranostic Applications.
abstract: Carbon-based nanomaterials serve as a type of smart material for photo-triggered disease theranostics. The inherent physicochemical properties of these nanomaterials facilitate their use for less invasive treatments. This review summarizes the properties and applications of materials including fullerene, nanotubes, nanohorns, nanodots and nanographenes for photodynamic nanomedicine in cancer and antimicrobial therapies. Carbon nanomaterials themselves do not usually act as photodynamic therapy (PDT) agents owing to the high hydrophobicity, however, when the surface is passivated or functionalized, these materials become great vehicles for PDT. Moreover, conjugation of carbonaceous nanomaterials with the photosensitizer (PS) and relevant targeting ligands enhances properties such as selectivity, stability, and high quantum yield, making them readily available for versatile biomedical applications.
authors.affiliation: Institute of Molecular Science, National Chiao-Tung University, Hsinchu 30010, Taiwan. karunya.albert@gmail.com.
authors.forename: Karunya
authors.initials: K
authors.lastname: Albert
authors.affiliation: Institute of Molecular Science, National Chiao-Tung University, Hsinchu 30010, Taiwan. hyhsu99@nctu.edu.tw.|Department of Applied Chemistry, National Chiao-Tung University, Hsinchu 30010, Taiwan. hyhsu99@nctu.edu.tw.
authors.forename: Hsin-Yun
authors.initials: HY
authors.lastname: Hsu
mesh_terms: D000818:Animals; D002244:Carbon / Q000737:chemistry*; D006801:Humans; D051379:Mice; D049329:Nanostructures / Q000737:chemistry*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000737:chemistry* / Q000627:therapeutic use; D013499:Surface Properties; D000068936:Theranostic Nanomedicine
chemical_list: D017319:Photosensitizing Agents; D002244:Carbon
keywords: carbon materials; nanomedicine; near infrared-triggered agents; photodynamic therapy; photosensitizer