title: Is dilution important: Factitious Total Creatine Kinase in case of Rhabdomyolysis?
abstract: Factitious test reports may result in incorrect diagnosis and incorrect management. Such incorrect diagnosis can be prevented by a vigilant biochemist. We report a case of Rhabdomyolysis presenting with extremely low total Creatine Kinase (CK) levels which was factitious. Running the sample in dilution resulted in a very high value of total CK which could have been missed if the sample was not run in dilution and the diagnosis of Rhabdomyolysis could have been missed.
authors.affiliation: Professor, Department of Biochemistry, Pondicherry Institute of Medical Sciences , Pondicherry, India .
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Nanda
authors.affiliation: Tutor, Department of Biochemistry, Pondicherry Institute of Medical Sciences , Pondicherry, India .
authors.forename: Asha
authors.initials: A
authors.lastname: Dinakaran
authors.affiliation: Associate Professor, Department of Biochemistry, Pondicherry Institute of Medical Sciences , Pondicherry, India .
authors.forename: Lopamudra
authors.initials: L
authors.lastname: Ray
keywords: Incorrect diagnosis; Muscle injury; Sample dilution; Substrate depletion