title: Glycaemic control by monoamine oxidase inhibition in a patient with type 1 diabetes.
abstract: We present clinical, electroencephalographic and low-resolution electromagnetic tomography data that support combined treatment with insulin and a monoamine oxidase inhibitor in a patient with type 1 diabetes. We suggest that brain imaging data can identify a subgroup of patients who are likely to benefit from an insulin regimen and monoamine oxidase inhibition to improve glycaemic control, cardiovascular function, normalize the circadian rhythm and restore perception of glycaemic awareness.
authors.affiliation: Emory Neurophysiologic Institute, Los Angeles, CA, USA.
authors.forename: Hamlin
authors.initials: H
authors.lastname: Emory
authors.affiliation: Emory Neurophysiologic Institute, Los Angeles, CA, USA.
authors.forename: Neptune
authors.initials: N
authors.lastname: Mizrahi
mesh_terms: D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000187:drug effects* / Q000378:metabolism; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D001931:Brain Mapping / Q000379:methods; D058256:Brain Waves / Q000187:drug effects*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000069036:Insulin Glargine / Q000008:administration & dosage; D061268:Insulin Lispro / Q000008:administration & dosage; D007333:Insulin Resistance; D061385:Insulins / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use*; D011237:Predictive Value of Tests; D014191:Tranylcypromine / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D061268:Insulin Lispro; D061385:Insulins; D008996:Monoamine Oxidase Inhibitors; D000069036:Insulin Glargine; D014191:Tranylcypromine
keywords: Relative power; low-resolution electromagnetic tomography; monoamine oxidase inhibitor; quantitative electroencephalography; type 1 diabetes