title: Case report: successful open resection of a symptomatic giant liver haemangioma during the second trimester of pregnancy.
abstract: Liver haemangiomas are consistently reported to be the commonest benign liver tumours and are most often incidental findings in asymptomatic individuals. Large lesions can become symptomatic, spontaneously rupture or result in a consumptive coagulopathy known as Kasabach-Merrit Syndrome. It is believed that the female sex hormones, particularly oestrogen, have an influence on haemangioma development and growth. The optimal management of large haemangiomas during the hyperoestrogenic state of pregnancy is poorly described in the current literature. To our knowledge, we describe only the second case of a giant hepatic haemangioma resection during pregnancy.
authors.affiliation: Department of hepatobiliary surgery and liver transplantation, Royal Free Hospital, London , United Kingdom angus.hann@nhs.net.
authors.forename: Angus
authors.initials: A
authors.lastname: Hann
authors.affiliation: Department of hepatobiliary surgery and liver transplantation, Royal Free Hospital, London , United Kingdom.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Osenda
authors.affiliation: Department of anaesthesia, Royal Free Hospital, London , United Kingdom.
authors.forename: Jon A
authors.initials: JA
authors.lastname: Reade
authors.affiliation: Department of obstetrics and gynaecology, Royal Free Hospital, London , United Kingdom.
authors.forename: Demetrius
authors.initials: D
authors.lastname: Economides
authors.affiliation: Department of hepatobiliary surgery and liver transplantation, Royal Free Hospital, London , United Kingdom.
authors.forename: Dinesh
authors.initials: D
authors.lastname: Sharma