title: The First Isolation of Aspergillus allahabadii from a Cormorant with Pulmonary Aspergillosis.
abstract: In this study, we report the first isolation of Aspergillus allahabadii from a Japanese cormorant with pulmonary aspergillosis. We performed molecular identification and antifungal susceptibility testing with the E-test. A 7-month-old male cormorant died because of uric acid deposition secondary to dehydration. Whitish nodular lesions were present on the caudal thoracic air sac in the right thoracic cavity. Histopathology revealed multifocal pyogranulomatous necrotic lesions with numerous fungal hyphae in the thoracic air sac. Identification of the etiologic agent was confirmed by comparative analyses of the sequences of the internal transcribed spacer (ITS) region and β-tubulin-encoding genes. According to the E-test, the minimum inhibitory concentrations of the isolate to amphotericin B, fluconazole, itraconazole, and voriconazole were 0.75 μg/ml, >256 μg/ml, 0.38 μg/ml, and 0.38 μg/ml, respectively.
authors.affiliation: Veterinary Pathobiology, Nihon University College of Bioresource Sciences.
authors.forename: Sue Yee
authors.initials: SY
authors.lastname: Lim
authors.forename: Rui
authors.initials: R
authors.lastname: Kano
authors.forename: Kenji
authors.initials: K
authors.lastname: Ooya
authors.forename: Shunta
authors.initials: S
authors.lastname: Kimura
authors.forename: Tokuma
authors.initials: T
authors.lastname: Yanai
authors.forename: Atsuhiko
authors.initials: A
authors.lastname: Hasegawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kamata
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology; D001230:Aspergillus / Q000187:drug effects / Q000302:isolation & purification*; D001715:Bird Diseases / Q000382:microbiology* / Q000635:transmission; D001717:Birds; D002648:Child; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology; D006801:Humans; D017964:Itraconazole / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D055732:Pulmonary Aspergillosis / Q000382:microbiology* / Q000635:transmission / Q000662:veterinary; D065819:Voriconazole / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B; D015725:Fluconazole; D065819:Voriconazole