title: Dropless Cataract Surgery: An Overview.
abstract: Risk reduction and the attainment of good outcomes in contemporary cataract surgery depend in part on patient compliance with a postoperative regimen of topical eye drops. Topical drops are expensive and challenging to instill properly for patients. The consequences of noncompliance or poor compliance can be significant for the patient (in the case of a complication) and for society (in the case of development of antibiotic resistance). For all of these reasons, new approaches that reduce the need for topical therapy are beginning to emerge, including intracameral injection, sustained or slow-release drug delivery mechanisms, and the recently introduced "Dropless cataract surgery," which involves intravitreal injection of single-use, compounded combination of antibiotics and corticosteroids. This paper is a review of the rationale for reducing topical therapy in cataract surgery prophylaxis, and what is known to date about the efficacy and safety of the dropless approach.
authors.affiliation: Minnesota Eye Consultants, 9801 Dupont Ave S., Suite 200, Bloomington, MN 55431. United States.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Lindstrom
authors.affiliation: Cumberland Eye Care, Crossville, TN. United States.
authors.forename: M Stewart
authors.initials: MS
authors.lastname: Galloway
authors.affiliation: Department of Ophthalmology, Poznan City Hospital, Poznan. Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Grzybowski
authors.affiliation: Eye Care Northwest, Sparta, NJ,. United States.
authors.forename: Jeffrey T
authors.initials: JT
authors.lastname: Liegner
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D002387:Cataract Extraction / Q000009:adverse effects*; D003692:Delayed-Action Preparations; D016503:Drug Delivery Systems; D006801:Humans; D058449:Intravitreal Injections; D009883:Ophthalmic Solutions / Q000009:adverse effects* / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy* / Q000601:surgery
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D003692:Delayed-Action Preparations; D009883:Ophthalmic Solutions
keywords: Cataract surgery; antibiotic prophylaxis; compliance; corticosteroid; endophthalmitis; intracameral; intravitreal; transzonular
  injection