title: Reply.
authors.affiliation: McGill University, Montreal, Canada.
authors.forename: Carlo A
authors.initials: CA
authors.lastname: Fallone
authors.affiliation: Hospital Universitario de la Princesa, Madrid, Spain.
authors.forename: Javier P
authors.initials: JP
authors.lastname: Gisbert
authors.affiliation: McMaster University, Hamilton, Ontario, Canada.
authors.forename: Naoki
authors.initials: N
authors.lastname: Chiba
authors.affiliation: University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Sander
authors.initials: S
authors.lastname: Veldhuyzen van Zanten
authors.affiliation: University of Arkansas for Medical Sciences, Little Rock, Arkansas.
authors.forename: Lori
authors.initials: L
authors.lastname: Fischbach
authors.affiliation: McMaster University, Hamilton, Ontario, Canada.
authors.forename: Richard H
authors.initials: RH
authors.lastname: Hunt
authors.affiliation: University of Toronto, Toronto, Ontario, Canada.
authors.forename: Nicola L
authors.initials: NL
authors.lastname: Jones
authors.affiliation: Kelowna General Hospital, Kelowna, British Columbia, Canada.
authors.forename: Craig
authors.initials: C
authors.lastname: Render
authors.affiliation: McMaster University, Hamilton, Ontario, Canada.
authors.forename: Grigorios I
authors.initials: GI
authors.lastname: Leontiadis
authors.affiliation: McMaster University, Hamilton, Ontario, Canada.
authors.forename: Paul
authors.initials: P
authors.lastname: Moayyedi
authors.affiliation: McMaster University, Hamilton, Ontario, Canada.
authors.forename: John K
authors.initials: JK
authors.lastname: Marshall