title: Palladium-Catalyzed Tandem Oxidative Arylation/Olefination of Aromatic Tethered Alkenes/Alkynes.
abstract: We describe herein a palladium-catalyzed tandem oxidative arylation/olefination reaction of aromatic tethered alkenes/alkynes for the synthesis of dihydrobenzofurans and 2 H-chromene derivatives. This reaction features a 1,2-difunctionalization of C-C π-bond with two C-H bonds using O2as terminal oxidant at room temperature. The products obtained are valuable synthons and important scaffolds in biological agents and natural products.
authors.affiliation: Department of Chemistry and FQRNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke St. W., Montreal, Quebec, H3A 0B8, Canada.|Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, PR China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, PR China.
authors.forename: Yinglan
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, PR China.
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.affiliation: Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, PR China.
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.affiliation: Department of Chemistry and FQRNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke St. W., Montreal, Quebec, H3A 0B8, Canada.
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Chemistry and FQRNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke St. W., Montreal, Quebec, H3A 0B8, Canada.
authors.forename: Wenbo
authors.initials: W
authors.lastname: Liu
authors.affiliation: Department of Chemistry and FQRNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke St. W., Montreal, Quebec, H3A 0B8, Canada.
authors.forename: Chao-Jun
authors.initials: CJ
authors.lastname: Li
keywords: 2H-chromene; Fujiwara-Moritani reaction; dihydrobenzofurans; oxygen; palladium