title: Efficacy of accelerated hydrogen peroxide®disinfectant on foot-and-mouth disease virus, swine vesicular disease virus and Senecavirus A.
abstract: OBJECTIVE
  In a laboratory, disinfectants used to inactivate pathogens on contaminated surfaces and to prevent spread of diseases often have adverse side effects on personnel and the environment. It is, therefore, essential to find safer, fast-acting and yet effective disinfectants. The objective of this study was to evaluate an accelerated hydrogen peroxide®(AHP®)-based disinfectant against high consequence foreign animal disease pathogens such as foot-and-mouth disease virus (FMDV) and swine vesicular disease virus (SVDV), as well as Senecavirus A (SVA), which causes similar lesions as FMDV and SVDV.
  
  
  RESULTS
  We tested varying dilutions and contact times of AHP against FMDV, SVDV and SVA by the standard US EPA and modified methods. AHP was effective against all three viruses, albeit at a higher concentration and double the manufacturer recommended contact time when testing wet films of SVDV.
  
  
  CONCLUSIONS
  AHP is an effective disinfectant against FMDV, SVDV and SVA.
  
  
  CONCLUSIONS
  AHP-based disinfectant can, therefore, be used in high containment laboratories working with FMDV, SVDV and related pathogens.
authors.affiliation: National Centre for Foreign Animal Disease (NCFAD), Winnipeg, MB, Canada.
authors.forename: K
authors.initials: K
authors.lastname: Hole
authors.affiliation: Virox Technologies Inc., Oakville, ON, Canada.
authors.forename: F
authors.initials: F
authors.lastname: Ahmadpour
authors.affiliation: National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Krishnan
authors.affiliation: National Centre for Foreign Animal Disease (NCFAD), Winnipeg, MB, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Stansfield
authors.affiliation: National Centre for Foreign Animal Disease (NCFAD), Winnipeg, MB, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Copps
authors.affiliation: National Centre for Foreign Animal Disease (NCFAD), Winnipeg, MB, Canada.|Department of Animal Science, University of Manitoba, Winnipeg, MB, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Nfon
mesh_terms: D000818:Animals; D004202:Disinfectants / Q000494:pharmacology*; D029822:Enterovirus B, Human / Q000187:drug effects*; D029544:Foot-and-Mouth Disease Virus / Q000187:drug effects*; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D010849:Picornaviridae / Q000187:drug effects*; D013552:Swine
chemical_list: D004202:Disinfectants; D006861:Hydrogen Peroxide
keywords: 
  FMDV
  ; 
  SVDV
  ; Senecavirus A; accelerated hydrogen peroxide®; disinfectant