title: Applications of Mesenchymal Stem Cells in Oral and Craniofacial Regeneration.
abstract: The field of tissue engineering and regenerative medicine has been rapidly expanded through multidisciplinary integration of research and clinical practice in response to unmet clinical needs for reconstruction of dental, oral, and craniofacial structures. The significance of the various types of stem cells, specifically mesenchymal stem cells derived from the orofacial tissues, ranging from dental pulp stem cells to periodontal ligament stem cells to mucosa/gingiva has been thoroughly investigated and their applications in tissue regeneration are outlined in this article.
authors.affiliation: Department of Oral and Maxillofacial Surgery/Pharmacology, University of Pennsylvania, School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104-6030, USA.
authors.forename: Pasha
authors.initials: P
authors.lastname: Shakoori
authors.affiliation: Department of Oral and Maxillofacial Surgery/Pharmacology, University of Pennsylvania, School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104-6030, USA.
authors.forename: Quanzhou
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Oral and Maxillofacial Surgery/Pharmacology, University of Pennsylvania, School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104-6030, USA. Electronic address: Anh.Le@uphs.upenn.edu.
authors.forename: Anh D
authors.initials: AD
authors.lastname: Le
mesh_terms: D000818:Animals; D003782:Dental Pulp / Q000166:cytology; D006801:Humans; D059630:Mesenchymal Stem Cells; D009061:Mouth Mucosa / Q000166:cytology; D019647:Oral Surgical Procedures / Q000379:methods*; D010513:Periodontal Ligament / Q000166:cytology; D044968:Regenerative Medicine / Q000379:methods*; D023822:Tissue Engineering / Q000379:methods*
keywords: Orofacial mesenchymal stem cells; Regenerative medicine; Stem cells; Tissue engineering