title: The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community.
abstract: Nanopore DNA strand sequencing has emerged as a competitive, portable technology. Reads exceeding 150 kilobases have been achieved, as have in-field detection and analysis of clinical pathogens. We summarize key technical features of the Oxford Nanopore MinION, the dominant platform currently available. We then discuss pioneering applications executed by the genomics community.
authors.affiliation: UC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA.
authors.forename: Miten
authors.identifier: 0000-0002-4571-3982
authors.initials: M
authors.lastname: Jain
authors.affiliation: UC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA.
authors.forename: Hugh E
authors.initials: HE
authors.lastname: Olsen
authors.affiliation: UC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA.
authors.forename: Benedict
authors.initials: B
authors.lastname: Paten
authors.affiliation: UC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA. makeson@soe.ucsc.edu.
authors.forename: Mark
authors.initials: M
authors.lastname: Akeson
mesh_terms: D000465:Algorithms; D000782:Aneuploidy; D019295:Computational Biology / Q000295:instrumentation / Q000379:methods*; D004247:DNA / Q000032:analysis / Q000235:genetics; D023281:Genomics / Q000295:instrumentation / Q000379:methods*; D059014:High-Throughput Nucleotide Sequencing / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D058608:Nanopores; D015203:Reproducibility of Results
chemical_list: D004247:DNA