title: Management, prevention and treatment of canine leishmaniosis in north-eastern Spain: an online questionnaire-based survey in the province of Girona with special emphasis on new preventive methods (CaniLeish vaccine and domperidone).
abstract: Knowledge of how canine leishmaniosis (CanL) is being managed clinically and its epidemiology is very important, since dogs are the main reservoir of human leishmaniosis. This study reports the results obtained through a questionnaire-based survey of veterinary practitioners in Girona province, a recognised, but non-documented endemic area in north-eastern Spain. The primary objective was to obtain data on the clinical management of CanL, focusing particularly on new preventive methods and therapeutic tools. The results show an extensive routine management of CanL cases and a widespread use of the CaniLeish (Virbac) vaccine and domperidone (Leisguard, Esteve). Adverse reactions were detected by a vast majority of the vaccine users (82 per cent), the most frequent being local reactions, apathy, fever and gastroenteritis. All the respondents had treated confirmed cases, and the therapeutic protocol most used was the combination of meglumine antimoniate (Glucantime, Merial) and allopurinol (Zyloric, GlaxoSmithKline).
authors.affiliation: Section of Parasitology, Department of Biology, Healthcare and the Environment, Faculty of Pharmacy, Universitat de Barcelona, Avda. Joan XXIII 27-31, 08028 Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Lladró
authors.affiliation: ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Picado
authors.affiliation: Section of Parasitology, Department of Biology, Healthcare and the Environment, Faculty of Pharmacy, Universitat de Barcelona, Avda. Joan XXIII 27-31, 08028 Barcelona, Spain.
authors.forename: C
authors.identifier: http://orcid.org/0000-0002-9930-3225
authors.initials: C
authors.lastname: Ballart
authors.affiliation: Section of Parasitology, Department of Biology, Healthcare and the Environment, Faculty of Pharmacy, Universitat de Barcelona, Avda. Joan XXIII 27-31, 08028 Barcelona, Spain.
authors.forename: M
authors.identifier: http://orcid.org/0000-0002-5088-9122
authors.initials: M
authors.lastname: Portús
authors.affiliation: Section of Parasitology, Department of Biology, Healthcare and the Environment, Faculty of Pharmacy, Universitat de Barcelona, Avda. Joan XXIII 27-31, 08028 Barcelona, Spain.
authors.forename: M
authors.identifier: http://orcid.org/0000-0002-8143-9773
authors.initials: M
authors.lastname: Gállego
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000453:epidemiology / Q000517:prevention & control* / Q000628:therapy*; D004285:Dogs; D004294:Domperidone / Q000627:therapeutic use; D006801:Humans; D020407:Internet; D007896:Leishmaniasis / Q000453:epidemiology / Q000517:prevention & control / Q000628:therapy / Q000662:veterinary*; D054332:Leishmaniasis Vaccines / Q000008:administration & dosage; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires
chemical_list: D054332:Leishmaniasis Vaccines; D004294:Domperidone
keywords: NE Spain; canine leishmaniasis; prevention; vaccine; web-questionnaire