title: Methodological evaluation of the noninvasive estimation of central systolic blood pressure in nontreated patients: the Bogalusa Heart Study.
abstract: OBJECTIVE
  This study sought to compare the estimation of central systolic blood pressure (cSBP) obtained by two different noninvasive devices, in addition to its comparisons with measured peripheral systolic blood pressure (pSBP), in a biracial (Black/White) community-based cohort.
  
  
  METHODS
  Estimations of cSBP by applanation tonometry were obtained in 586 participants of the Bogalusa Heart Study (mean age: 43.5 years; 69% White, 54% women) using two different commonly used instruments: Omron HEM-9000AI and SphygmoCor CPV. pSBP was measured using a standard auscultatory technique.
  
  
  RESULTS
  The estimation of cSBP by the Omron device was higher than that of the SphygmoCor device (124.2±17.1 vs. 111.4±15.2 mmHg, P<0.001). Moreover, cSBP by Omron was significantly higher than peripheral blood pressure (124.2±17.1 vs. 119.4±15.6 mmHg, P<0.001), whereas cSBP by SphygmoCor was significantly lower than pSBP (111.4±15.2 vs. 119.4±15.6 mmHg, P<0.001). Similar results were observed in race-specific and sex-specific analyses.
  
  
  CONCLUSIONS
  These findings support the hypothesis that notable differences exist in the estimation of cSBP provided by the instruments utilized in this study. Further standardization studies are required to establish the most appropriate noninvasive estimation of cSBP before this parameter may be considered in the assessment, prediction, and prevention of cardio-metabolic risk and overt cardiovascular disease in clinical practice.
authors.affiliation: aDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine bHeart and Vascular Institute, Tulane University School of Medicine, New Orleans, Louisiana cHeartGEN Institute dHeart and Vascular Center, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
authors.forename: Camilo
authors.initials: C
authors.lastname: Fernandez
authors.forename: Robert
authors.initials: R
authors.lastname: Hsu
authors.forename: Gary
authors.initials: G
authors.lastname: Sander
authors.forename: Azad
authors.initials: A
authors.lastname: Hussain
authors.forename: Rupert
authors.initials: R
authors.lastname: Barshop
authors.forename: Shengxu
authors.initials: S
authors.lastname: Li
authors.forename: Tian
authors.initials: T
authors.lastname: Shu
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.forename: Patrycja
authors.initials: P
authors.lastname: Galazka
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.forename: Lydia
authors.initials: L
authors.lastname: Bazzano
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Giles
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000295:instrumentation* / Q000379:methods*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged