title: Circadian clocks: Not your grandfather's clock.
abstract: The last 20 years have seen the rapid evolution of our understanding of the molecular genes and networks that enable almost all forms of life to generate 24-hour-or circadian-rhythms. One finding has been particularly exciting: that the molecular circadian clock resides in almost all of the cells of the body and that the clock regulates the timing of many cellular and signaling pathways associated with multiple disease states. Such advances represent a new frontier for medicine: circadian medicine.
authors.affiliation: Director, Center for Sleep and Circadian Biology, Northwestern University, Cook Hall, 2220 Campus Drive, Evanston, IL 60208, USA. fturek@northwestern.edu.|Charles E. and Emma H. Morrison Professor of Biology, Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, Evanston, IL 60201, USA.|Professor, Departments of Neurology and Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Fred W
authors.initials: FW
authors.lastname: Turek
mesh_terms: D000818:Animals; D057906:Circadian Clocks / Q000235:genetics*; D006224:Cricetinae; D004194:Disease / Q000235:genetics*; D053263:Gene Regulatory Networks; D000066502:Grandparents; D006801:Humans; D008511:Medicine / Q000639:trends; D051379:Mice; D015398:Signal Transduction