title: [Virulence mechanisms of enteropathogenic Escherichia coli].
abstract: Acute diarrheal disease (ADD) is a global public health problem, especially in developing countries and is one of the causes of mortality in children under five. ADD etiologic agents include viruses, bacteria and parasites in that order. Escherichia coli bacteria it is classified as a major diarrheagenic agent and transmitted by consuming contaminated water or undercooked foods. This review compiled updates on information virulence factors and pathogenic mechanisms involved in adhesion and colonization of seven pathotypes of E. coli called enteropathogenic E. coli (EPEC), enterotoxigenic E. coli (ETEC), enteroinvasive E. coli (EIEC), shigatoxigenic E. coli (STEC), enteroaggregative E. coli (EAEC) and diffusely-adherent E. coli (DAEC). A final pathotype, adherent-invasive E. coli (AIEC) associated with Crohn's disease was also reviewed. The diarrheagenic pathotypes of E. coli affect different population groups and knowledge of the molecular mechanisms involved in the interaction with the human is important to guide research towards the development of vaccines and new tools for diagnosis and control.
authors.forename: Ana Elvira
authors.initials: AE
authors.lastname: Farfán-García
authors.forename: Sandra Catherine
authors.initials: SC
authors.lastname: Ariza-Rojas
authors.forename: Fabiola Andrea
authors.initials: FA
authors.lastname: Vargas-Cárdenas
authors.forename: Lizeth Viviana
authors.initials: LV
authors.lastname: Vargas-Remolina
mesh_terms: D003967:Diarrhea / Q000382:microbiology* / Q000821:virology; D054308:Enteropathogenic Escherichia coli / Q000145:classification / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D006801:Humans; D037521:Virulence Factors
chemical_list: D037521:Virulence Factors