title: Extrahepatic biliary obstrution secondary to neuroendocrine tumor of the common hepatic duct.
abstract: BACKGROUND
  Primary neuroendocrine tumors (NET) of the extrahepatic biliary tree are a rare entity with less than 100 reported cases in the literature.
  
  
  METHODS
  Here, we report a case of NET of the extrahepatic bile duct in a 64-year-old male patient presenting with painless jaundice, direct hyperbilirubinemia, and mildly elevated transaminases. Diagnostic workup with an ultrasound revealed dilation of the intrahepatic biliary ducts, without cholelithiasis or choledocholithiasis. Additional cross sectional imaging identified a stricture at the confluence of the common hepatic and cystic duct junction. Given lack of additional findings presumptive diagnosis of localized klatskin's tumor was made. The patient subsequently underwent resection of the common bile duct and roux-en-y hepaticojejunostomy reconstruction. Final pathologic diagnosis showed G2 well-differentiated NET of the extrahepatic bile duct, measuring 1.3×1.1×1cm.
  
  
  CONCLUSIONS
  When a patient is evaluated for a primary bile duct neoplasm, differentiation between cholangiocarcinoma and an unusual bile duct tumor, such as a NET is very difficult before surgical resection and histologic review.
  
  
  CONCLUSIONS
  NET of the extrahepatic biliary tree are a rare entity. Typical presentation is with painless jaundice and other symptoms related to obstruction of the biliary tree and the diagnosis is usually made post-operatively.
authors.affiliation: Department of Surgery, Wayne State University/Detroit Medical Center, 6C UHC, 4201 St. Antoine, Detroit, MI 48226, USA. Electronic address: dr.farazali@gmail.com.
authors.forename: Faraz A
authors.initials: FA
authors.lastname: Khan
authors.affiliation: Department of Surgery, Wayne State University/Detroit Medical Center, 6C UHC, 4201 St. Antoine, Detroit, MI 48226, USA.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Stevens-Chase
authors.affiliation: Department of Surgery, Wayne State University/Detroit Medical Center, 6C UHC, 4201 St. Antoine, Detroit, MI 48226, USA.
authors.forename: Rahman
authors.initials: R
authors.lastname: Chaudhry
authors.affiliation: Department of Surgery, Wayne State University/Detroit Medical Center, 6C UHC, 4201 St. Antoine, Detroit, MI 48226, USA.
authors.forename: Asra
authors.initials: A
authors.lastname: Hashmi
authors.affiliation: Department of Surgery, Wayne State University/Detroit Medical Center, 6C UHC, 4201 St. Antoine, Detroit, MI 48226, USA.
authors.forename: David
authors.initials: D
authors.lastname: Edelman
authors.affiliation: Department of Surgery, Wayne State University/Detroit Medical Center, 6C UHC, 4201 St. Antoine, Detroit, MI 48226, USA.
authors.forename: Donald
authors.initials: D
authors.lastname: Weaver
keywords: Biliary obstruction; Cholangiocarcinoma; Extrahepatic bile duct; Neuroendocrine tumor; Unusual biliary tumors