title: Photodynamic therapy as an alternative treatment for relapsed or refractory mycosis fungoides: A systemic review.
abstract: Mycosis fungoides is the most common cutaneous T-cell lymphoma. It is characterized by slow progress over years to decades, developing from patches to infiltrated plaques, and sometimes to tumors. Therapies such as localized chemotherapy, photochemotherapy and radiotherapy are often employed when lesions of refractory or relapsing mycosis fungoides are resistant to conventional therapies. However, these methods have acute or chronic side effects and toxicity, which may accumulate with repeated and protracted treatment cycles. Photodynamic therapy is a promising, well-tolerated option for the treatment of localized lesions with excellent cosmetic outcomes. In this article, we systematically reviewed and discussed clinical application of photodynamic therapy in relapsed or refractory mycosis fungoides. There are 20 papers included in this review article.
authors.affiliation: School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Jingwen
authors.initials: J
authors.lastname: Xue
authors.affiliation: University of Missouri - Kansas City School of Medicine, Kansas City, MO, United States.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Dermatology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: yuehualiu@263.net.
authors.forename: Yuehua
authors.initials: Y
authors.lastname: Liu
mesh_terms: D006801:Humans; D000622:Aminolevulinic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D009182:Mycosis Fungoides / Q000188:drug therapy; D010778:Photochemotherapy / Q000295:instrumentation / Q000379:methods; D017319:Photosensitizing Agents / Q000627:therapeutic use; D012878:Skin Neoplasms / Q000188:drug therapy
chemical_list: D000622:Aminolevulinic Acid; C114767:delta-aminolevulinic acid methyl ester; D017319:Photosensitizing Agents
keywords: Aminolevulinic acid; Methyl aminolevulinic acid; Photodynamic therapy; Relapsed or refractory mycosis fungoides