title: Device-associated infections in a paediatric intensive care unit in Pakistan.
abstract: This study assessed the effect of implementation of active infection control and surveillance on the occurrence of device-associated infections (DAIs) in a paediatric intensive care unit (PICU) from 2012 to 2015. There were 1378 patients, equating to 4632 patient-days, on the PICU, and 29 DAI episodes, giving an incidence rate of 2.1% and an incidence density rate of 6.26 per 1000 patient-days. The rates of central-line-associated bloodstream infections, ventilator-associated pneumonia and catheter-related urinary tract infections were 7/1000 central-line-days, 1.17/1000 ventilator-days and 0.24/1000 urinary-catheter-days, respectively. Despite the overall low rate of DAIs in the PICU, there was a relatively high rate of central-line-associated bloodstream infections.
authors.affiliation: Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan. Electronic address: anwar.haq@aku.edu.
authors.forename: A
authors.initials: A
authors.lastname: Haque
authors.affiliation: Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: S A
authors.initials: SA
authors.lastname: Ahmed
authors.affiliation: Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan; Department of Infection Control, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Z
authors.initials: Z
authors.lastname: Rafique
authors.affiliation: Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Q
authors.initials: Q
authors.lastname: Abbas
authors.affiliation: Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: H
authors.initials: H
authors.lastname: Jurair
authors.affiliation: Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: S A
authors.initials: SA
authors.lastname: Ali
mesh_terms: D055499:Catheter-Related Infections / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D004864:Equipment and Supplies / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007362:Intensive Care Units; D008297:Male; D010154:Pakistan / Q000453:epidemiology; D053717:Pneumonia, Ventilator-Associated / Q000453:epidemiology*; D012189:Retrospective Studies
keywords: Children; Device-associated infection; Incidence; Outcome; Paediatric intensive care unit