title: Graphene oxide-based fluorescent sensor for sensitive turn-on detection of sinapine.
abstract: Sinapine (SP) has attracted extensive attention in food and medical field because it is a crucial component in many plants with unique physiological activities. Here, we reported a fluorescent sensor based on the unique properties of graphene oxide (GO) for rapid, sensitive detection of SP concentration. In this strategy, GO has stronger affinity toward SP and can be also served as a quencher for DNA fluorescence probe. The fluorescence can make a recovery by the addition of SP, which can competitively desorb probe from the surface of GO, and the SP can thus be monitored by recording the fluorescence change. Because of the low background assays and high quenching ability offered by GO, the developed method provides a great potential for plant-derived molecules research.
authors.affiliation: Department of Product Processing and Nutriology, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Hubei Key Laboratory of Lipid Chemistry and Nutrition, Ministry of Agriculture Key Laboratory of Oil Crops Biology, Wuhan 430062, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Xiang
authors.affiliation: Department of Product Processing and Nutriology, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Hubei Key Laboratory of Lipid Chemistry and Nutrition, Ministry of Agriculture Key Laboratory of Oil Crops Biology, Wuhan 430062, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Han
authors.affiliation: Department of Product Processing and Nutriology, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Hubei Key Laboratory of Lipid Chemistry and Nutrition, Ministry of Agriculture Key Laboratory of Oil Crops Biology, Wuhan 430062, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Product Processing and Nutriology, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Hubei Key Laboratory of Lipid Chemistry and Nutrition, Ministry of Agriculture Key Laboratory of Oil Crops Biology, Wuhan 430062, China. Electronic address: xiangshi19850130@163.com.
authors.forename: Fenghong
authors.initials: F
authors.lastname: Huang
mesh_terms: D002794:Choline / Q000031:analogs & derivatives* / Q000032:analysis; D005240:Feasibility Studies; D005456:Fluorescent Dyes / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; C005685:sinapine; D006108:Graphite; D002794:Choline
keywords: DNA fluorescence probe; Fluorescent sensor; Graphene oxide; Plant-derived molecules; Sinapine