title: Cordyceps collected from Bhutan, an appropriate alternative of Cordyceps sinensis.
abstract: Natural Cordyceps collected in Bhutan has been widely used as natural Cordyceps sinensis, an official species of Cordyceps used as Chinese medicines, around the world in recent years. However, whether Cordyceps from Bhutan could be really used as natural C. sinensis remains unknown. Therefore, DNA sequence, bioactive components including nucleosides and polysaccharides in twelve batches of Cordyceps from Bhutan were firstly investigated, and compared with natural C. sinensis. Results showed that the fungus of Cordyceps from Bhutan was C. sinensis and the host insect belonged to Hepialidae sp. In addition, nucleosides and their bases such as guanine, guanosine, hypoxanthine, uridine, inosine, thymidine, adenine, and adenosine, as well as compositional monosaccharides, partial acid or enzymatic hydrolysates, molecular weights and contents of polysaccharides in Cordyceps from Bhutan were all similar to those of natural C. sinensis. All data suggest that Cordyceps from Bhutan is a rational alternative of natural C. sinensis, which is beneficial for the improvement of their performance in health and medicinal food areas.
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
authors.forename: Ding-Tao
authors.initials: DT
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
authors.forename: Guang-Ping
authors.initials: GP
authors.lastname: Lv
authors.affiliation: National Institutes for Food and Drug Control, Tiantan Xili 2, Beijing, 100050, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zheng
authors.affiliation: National Institutes for Food and Drug Control, Tiantan Xili 2, Beijing, 100050, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.|National Institutes for Food and Drug Control, Tiantan Xili 2, Beijing, 100050, China.
authors.forename: Shuang-Cheng
authors.initials: SC
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
authors.forename: Shao-Ping
authors.initials: SP
authors.lastname: Li
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
mesh_terms: D001631:Bhutan; D002851:Chromatography, High Pressure Liquid; D016000:Cluster Analysis; D032661:Cordyceps / Q000235:genetics / Q000502:physiology*; D058893:DNA Barcoding, Taxonomic; D008970:Molecular Weight; D009705:Nucleosides / Q000032:analysis; D011134:Polysaccharides / Q000032:analysis
chemical_list: D009705:Nucleosides; D011134:Polysaccharides