title: Adult Onset Still's Disease With Different Antibodies: A Case Report and Review of Literature.
abstract: Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. There is not currently any specific serological markers for AOSD , and  diagnosis still relying on the exclusion of other likely diagnoses. Yamaguchi's criteria are used as a diagnostic criterion which contains negative serologic markers for other collagen vascular diseases including systemic lupus erythematosus and rheumatoid arthritis. Here we report a 28-year-old woman with arthralgia, fever, rash, leukocytosis, lymphadenopathy, sore throat, abnormal liver function and negative rheumatoid factor and ANA but  seropositive for anti-CCP, anti-dsDNA, and C-ANCA. It seems that despite AOSD is considered as a seronegativedisorder; it should be remembered in patients with compatible findings who are seropositive.
authors.affiliation: Department of Rheumatology, Diabetes Research Center, Mazandaran University of Medical Sciences, Mazandaran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Mobini
authors.affiliation: Department of Infectious Diseases, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Mazandaran, Iran.
authors.forename: Roya
authors.initials: R
authors.lastname: Ghasemian
authors.affiliation: Department of Infectious Diseases, Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences, Mazandaran, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Zameni
mesh_terms: D000328:Adult; D000906:Antibodies / Q000097:blood*; D018771:Arthralgia / Q000209:etiology; D015415:Biomarkers; D005076:Exanthema; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D016706:Still's Disease, Adult-Onset / Q000276:immunology* / Q000503:physiopathology*
chemical_list: D000906:Antibodies; D015415:Biomarkers
keywords: ANCA; Adult-onset Still’s disease; Anti CCP; Anti-dsDNA; Polyarthralgia