title: Localization of bleeding sites in patients with hemoptysis based on their chest computed tomography findings: a retrospective cohort study.
abstract: The aim of this study was to propose a localization strategy for bleeding sites in hemoptysis patients using their chest computed tomography (CT) findings.
  
  
  
  Between January 2005 and July 2009, the chest CT findings of 161 hemoptysis patients were retrospectively reviewed. Following chest CT, the lobe with the most prominent ground glass attenuation (GGA) or specific lesions with the potential to cause pulmonary hemorrhage were analysed to develop a localization strategy for bleeding sites. Fibre optic bronchoscopy (FOB) findings of active bleeding were used as the standard reference for the bleeding sites.
  
  
  
  The concordance rate between the most prominent GGA and FOB findings was higher than that between specific lesions and FOB findings (Kappa value [k] = 0.751 vs. 0.448, p < 0.001). Among the specific lesions, there were high concordance rates between lung cancer and FOB findings (3/3, 100%) and fungus balls and FOB findings (8/9, 89%). The agreement of localization of the bleeding site between FOB findings and the localization strategy based on chest CT findings including the most prominent GGA, lung cancer and fungus balls, showed almost perfect (k = 0.904).
  
  
  
  The localization of bleeding sites in hemoptysis patients could be determined by chest CT findings such as the most prominent GGA, malignancy and fungus ball.
authors.affiliation: Department of Radiology, Chonnam National University Medical School, 42 Jebongro, Donggu, Gwangju, 61469, South Korea.
authors.forename: Hyun Ju
authors.initials: HJ
authors.lastname: Seon
authors.affiliation: Department of Radiology, Chonnam National University Medical School, 42 Jebongro, Donggu, Gwangju, 61469, South Korea.
authors.forename: Yun-Hyeon
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Chonnam National University Medical School, 42 Jebongro, Donggu, Gwangju, 61469, South Korea. yskwon@jnu.ac.kr.
authors.forename: Yong-Soo
authors.identifier: 0000-0001-5121-4488
authors.initials: YS
authors.lastname: Kwon
mesh_terms: D000368:Aged; D001987:Bronchiectasis / Q000150:complications; D001999:Bronchoscopy; D005260:Female; D006469:Hemoptysis / Q000000981:diagnostic imaging* / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000150:complications; D056910:Republic of Korea; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
keywords: Fungus ball; Ground glass attenuation; Malignancy; Massive hemoptysis