title: Sufficient intake of high amylose cornstarch maintains high colonic hydrogen production for 24 h in rats.
abstract: Colonic hydrogen (H2) can suppress oxidative stress and damage in the body. We examined the minimum requirement of high amylose cornstarch (HAS) to maintain high colonic H2production for 24 h. Ileorectostomized and sham-operated rats were fed a control diet supplemented with or without 20% HAS for 7 days. Colonic starch utilization was determined. Next, rats were fed the control diet with or without 10% or 20% HAS for 14 or 28 days, respectively. Breath and flatus H2excretion for 24 h was measured. 1.04 g of resistant fraction in HAS was utilized for 24 h by colonic bacteria. High H2excretion was not maintained for 24 h in rats fed the 10% HAS diet, from which only 0.89 g of resistant starch was estimated to be delivered. High colonic H2production for 24 h would be maintained by delivering more HAS to the large intestine than is utilized.
authors.affiliation: a College of Agriculture , Academic Institute, Shizuoka University , Shizuoka , Japan.|b Faculty of Health and Welfare Science, Department of Nutritional Sciences , Nayoro City University , Nayoro , Japan.
authors.forename: Naomichi
authors.initials: N
authors.lastname: Nishimura
authors.affiliation: b Faculty of Health and Welfare Science, Department of Nutritional Sciences , Nayoro City University , Nayoro , Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanabe
authors.affiliation: b Faculty of Health and Welfare Science, Department of Nutritional Sciences , Nayoro City University , Nayoro , Japan.
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Yamamoto
mesh_terms: D000688:Amylose / Q000737:chemistry*; D000818:Animals; D003106:Colon / Q000187:drug effects* / Q000378:metabolism*; D004032:Diet; D004063:Digestion; D004305:Dose-Response Relationship, Drug; D006859:Hydrogen / Q000378:metabolism*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013213:Starch / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D006859:Hydrogen; D013213:Starch; D000688:Amylose
keywords: colonic fermentation; high amylose cornstarch; hydrogen; rats; resistant starch