title: d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine.
authors.affiliation: From the Departments of Psychiatry and of Radiology, College of Physicians and Surgeons, Columbia University, New York; the Nathan Kline Institute for Psychiatric Research, Orangeburg, N.Y.; and the Department of Radiology, Weill Medical College, Cornell University, New York.
authors.forename: Joshua T
authors.initials: JT
authors.lastname: Kantrowitz
authors.affiliation: From the Departments of Psychiatry and of Radiology, College of Physicians and Surgeons, Columbia University, New York; the Nathan Kline Institute for Psychiatric Research, Orangeburg, N.Y.; and the Department of Radiology, Weill Medical College, Cornell University, New York.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Milak
authors.affiliation: From the Departments of Psychiatry and of Radiology, College of Physicians and Surgeons, Columbia University, New York; the Nathan Kline Institute for Psychiatric Research, Orangeburg, N.Y.; and the Department of Radiology, Weill Medical College, Cornell University, New York.
authors.forename: Xiangling
authors.initials: X
authors.lastname: Mao
authors.affiliation: From the Departments of Psychiatry and of Radiology, College of Physicians and Surgeons, Columbia University, New York; the Nathan Kline Institute for Psychiatric Research, Orangeburg, N.Y.; and the Department of Radiology, Weill Medical College, Cornell University, New York.
authors.forename: Dikoma C
authors.initials: DC
authors.lastname: Shungu
authors.affiliation: From the Departments of Psychiatry and of Radiology, College of Physicians and Surgeons, Columbia University, New York; the Nathan Kline Institute for Psychiatric Research, Orangeburg, N.Y.; and the Department of Radiology, Weill Medical College, Cornell University, New York.
authors.forename: J John
authors.initials: JJ
authors.lastname: Mann
mesh_terms: D001923:Brain Chemistry / Q000187:drug effects*; D003523:Cycloserine / Q000494:pharmacology*; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology*; D018698:Glutamic Acid / Q000032:analysis*; D005973:Glutamine / Q000032:analysis*; D006801:Humans; D007649:Ketamine / Q000494:pharmacology*; D066244:Proton Magnetic Resonance Spectroscopy; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
chemical_list: D018690:Excitatory Amino Acid Agonists; D005973:Glutamine; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D007649:Ketamine; D003523:Cycloserine
keywords: Antidepressants; Biological Markers; Research Design And Methods