title: Paediatric traumatic brain injury: Presentation, prognostic indicators and Outcome analysis from a tertiary care center in a developing country.
abstract: Traumatic brain injury (TBI) is the leading cause of morbidity and mortality in children worldwide. This study was conducted to report the presentation, management, outcomes and prognostic indicators in a large series of patients from a tertiary care centre in a developing country. It is a review of prospectively collected data of paediatric patients with TBI admitted at our centre between July 2010 and December 2013. A total of 291 patients with a mean age of 7.2±5.0 years were dichotomised into survivors and non-survivors, and variables were compared between the two groups. The mean post-resuscitation Glasgow coma scale (GCS) score was 11.6±3.9, mean Marshall Score was 2.26±0.95 and the mean revised trauma score at presentation was 10.58±1.7. Younger age, lower GCS score after resuscitation, lower revised trauma score, absent cisterns on imaging, associated subarachnoid haemorrhage (SAH) and intraventricular haemorrhage (IVH) and a lower Marshall score were associated with higher mortality.
authors.affiliation: Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Badar
authors.initials: B
authors.lastname: Ujjan
authors.affiliation: Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Waqas
authors.affiliation: Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Muhammad Babar
authors.initials: MB
authors.lastname: Khan
authors.affiliation: Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Saqib Kamran
authors.initials: SK
authors.lastname: Bakhshi
authors.affiliation: Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Muhammad Ehsan
authors.initials: ME
authors.lastname: Bari
mesh_terms: D000070642:Brain Injuries, Traumatic / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D015600:Glasgow Coma Scale; D006801:Humans; D011379:Prognosis; D012189:Retrospective Studies; D062606:Tertiary Care Centers / Q000706:statistics & numerical data*; D016896:Treatment Outcome
keywords: Traumatic brain injury, Paediatrics, Prognostic factors, Outcomes, Developing country.