title: 10-year follow-up after implantation of the Bryan Cervical Disc Prosthesis.
abstract: Cervical arthroplasty is being used as an alternative for cervical fusion, but long-term follow-up results have rarely been reported. In this paper, we present 10-year follow-up results after implantation of the Bryan Cervical Disc Prosthesis in a single center.
  
  
  
  89 patients underwent implantation of a single-level Bryan Cervical Disc Prosthesis to treat radiculopathy and/or myelopathy. Clinical (Neurological Success, Neck Disability Index (NDI), Neck- and Arm-Pain, and SF-36) and radiological follow-up was prospectively organized up to 10 years after surgery. Adverse events and second surgeries were recorded and evaluated.
  
  
  
  Ten-year follow-up data were available for 72 (81%) patients. Maintenance or improvement of the neurological state was seen in 89% of patients after 10-year follow-up. SF-36 PCS scores improved significantly at all follow-up points. SF-36 MCS improvement was significant at 4 and 6 year, but not at 8- and 10-year follow-up. Significant improvement for NDI, and Neck- and Arm-Pain scores was found for the subgroup of patients in whom these data were available. Mean angular motion of the prosthesis at 10-year follow-up was 8.6°. Mobility of the device, defined as >2° of angular motion, was reached in 81% of patients. During the study period, 21 patients (24%) developed new or recurrent radiculopathy or myelopathy, the majority of these being treated conservatively. Seven patients (8%) required 8 additional spine surgeries to treat persistent or recurrent symptoms. Of these, 2 patients (2%) were reoperated at the index level and at 5 (6%) an adjacent level.
  
  
  
  In this study, favorable long-term clinical outcome after implantation of the Bryan Cervical Disc Prosthesis was seen, with the majority of prostheses remaining mobile after 10-year follow-up. However, still 6% of patients required adjacent level surgery.
authors.affiliation: Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium. Joost.dejaegher@uzleuven.be.
authors.forename: Joost
authors.identifier: 0000-0002-0050-5485
authors.initials: J
authors.lastname: Dejaegher
authors.affiliation: Division of Biomechanics, KU Leuven, Heverlee, Belgium.
authors.forename: Joris
authors.initials: J
authors.lastname: Walraevens
authors.affiliation: Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Johannes
authors.initials: J
authors.lastname: van Loon
authors.affiliation: Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Frank
authors.initials: F
authors.lastname: Van Calenbergh
authors.affiliation: Department of Radiology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Philippe
authors.initials: P
authors.lastname: Demaerel
authors.affiliation: Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Goffin
mesh_terms: D002574:Cervical Vertebrae / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery*; D019637:Orthopedic Procedures / Q000295:instrumentation / Q000379:methods; D019919:Prosthesis Implantation / Q000295:instrumentation / Q000379:methods
keywords: Bryan cervical disc prosthesis; Cervical disc arthroplasty; Cervical disc degeneration; Cervical spine