title: Converting Red Blood Cells to Efficient Microreactors for Blood Detoxification.
abstract: A simple method to convert red blood cells (RBCs) into efficient microreactors is reported. Triton X-100 is employed at finely tuned concentrations to render RBCs highly permeable to substrates, while low concentrations of glutaraldehyde are used to stabilize cells. The ability for blood detoxification of these microreactors is demonstrated.
authors.affiliation: Department of PET Center, Xiangya Hospital, Central South University, Changsha, 410008, China.|Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Can
authors.initials: C
authors.lastname: Xu
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Xiangyu
authors.initials: X
authors.lastname: Yang
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Xiao
authors.initials: X
authors.lastname: Fu
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Rui
authors.initials: R
authors.lastname: Tian
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Orit
authors.initials: O
authors.lastname: Jacobson
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Zhantong
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Nan
authors.initials: N
authors.lastname: Lu
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Yijing
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Wenpei
authors.initials: W
authors.lastname: Fan
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Fuwu
authors.initials: F
authors.lastname: Zhang
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Gang
authors.initials: G
authors.lastname: Niu
authors.affiliation: Department of PET Center, Xiangya Hospital, Central South University, Changsha, 410008, China.
authors.forename: Shuo
authors.initials: S
authors.lastname: Hu
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Iqbal Unnisa
authors.initials: IU
authors.lastname: Ali
authors.affiliation: Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
mesh_terms: D004912:Erythrocytes; D005976:Glutaral
chemical_list: D005976:Glutaral
keywords: Triton X-100 (TX); blood detoxification; glutaraldehyde (GA); microreactors; red blood cells (RBC)