title: Sex differences in the association between stroke and bone mineral density in elderly Koreans: The Korean National Health and Nutrition Examination Survey, 2008-2010.
abstract: OBJECTIVE
  The aim of this study was to investigate whether osteoporosis is more prevalent in elderly Korean people who have had a stroke and whether the association differs by sex.
  
  
  METHODS
  A total of 3806 elderly subjects (1951 men and 1855 women) from the Korea National Health and Nutrition Examination Survey were included in this study. Stroke history was determined by self-administered questionnaire. Bone mineral density (BMD) was measured at the lumbar spine, total hip, and neck of the femur using dual-energy X-ray absorptiometry. It was categorized as normal, osteopenia, or osteoporosis.
  
  
  RESULTS
  In men who had had a stroke, the prevalence of osteoporosis was greater than that of both osteopenia and normal BMD, and the prevalence of osteopenia was greater than that of normal BMD (p<0.001). However, there were no significant differences in BMD level among women who had had a stroke. Men who had had a stroke undertook less vigorous exercise and moderate-or-vigorous exercise than did men who had not had a stroke (p=0.002 and 0.030, respectively). After adjusting for all covariates, the mean BMD at the lumbar spine, total hip and neck of the femur was lower in men who had had a stroke than in men who had not (p=0.034, 0.002, and 0.005, respectively). There were no significant differences in mean BMD at any of the three sites between women who had and women who had not had a stroke.
  
  
  CONCLUSIONS
  Men who have had a stroke have a higher prevalence of osteopenia and osteoporosis, and have lower BMD at the total hip and femur neck than men who have not had a stroke.
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Hye-Rim
authors.initials: HR
authors.lastname: Jeon
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Jung Keun
authors.initials: JK
authors.lastname: Park
authors.affiliation: Department of Medical Statistics, Catholic University College of Medicine, Seoul, South Korea.
authors.forename: Kyung-Do
authors.initials: KD
authors.lastname: Han
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Ji-Hyun
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Jinnie
authors.initials: J
authors.lastname: Yoon
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea.
authors.forename: Seok-Won
authors.initials: SW
authors.lastname: Park
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea. Electronic address: mrchir@naver.com.
authors.forename: Yang-Hyun
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, South Korea. Electronic address: chokh@korea.ac.kr.
authors.forename: Kyung-Hwan
authors.initials: KH
authors.lastname: Cho
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density / Q000502:physiology*; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging; D005272:Femur Neck / Q000000981:diagnostic imaging; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000453:epidemiology*; D010456:Peptides, Cyclic; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012727:Sex Characteristics; D020521:Stroke / Q000453:epidemiology*; D011795:Surveys and Questionnaires
chemical_list: D010456:Peptides, Cyclic; C500144:cormycin A
keywords: Bone mineral density; Elderly; Korean National Health and Nutrition Examination Survey; Osteoporosis; Stroke