title: Value of the Ultrasound in the Study of Ovarian Reserve for Prediction of Oocyte Recovery.
abstract: PurposeTo identify which methods used in the assessment of the ovarian reserve are exclusive or complementary to identify the best response to follicle development.MethodsRetrospective cohort study, involving patients undergoing assisted reproduction treatment at the Instituto de Medicina Reprodutiva e Fetal, from April 2009 to July 2014. Age, biochemical tests, and ultrasound were assessed. The data were analyzed to predict the follicular development and the relation between them, using, for statistical analysis, Statistical Package for Social Sciences software.ResultsOut of the 293 couples included, 50.2% presented infertility by ovarian factor. Considering the age as the main variable, a significant negative correlation with the volume of both ovaries was observed (right ovary, r = 0.21; left ovary, r = -0.22; bothp< 0.0001), and with the antral follicle count (right ovary, r = -0.38; left ovary, r = -0.47; bothp< 0.0001). Considering the antral follicle count as the main variable, a significant positive correlation with the total recruited oocytes was observed. When we correlated the antral follicle count with the recruited follicles larger than 18 mm, we observed that, with a cutoff of 12 antral follicles, there is a positive predictive value of 99%, and an area under the ROC curve of 0.76.ConclusionWe concluded from our study that age and antral follicle count are effective predictors of ovarian response in cycles of assisted reproduction. The ovarian volume, as well as the anti-Müllerian hormone dosage, seem to be adequate markers of the ovarian reserve.
authors.affiliation: Gynecology and Obstetrics Department, Faculdade de Medicina de São José do Rio Preto, Instituto de Medicina Reprodutiva e Fetal, São José do Rio Preto, SP, Brazil.
authors.forename: Meire
authors.initials: M
authors.lastname: Spressão
authors.affiliation: Gynecology and Obstetrics Department, Faculdade de Medicina de São José do Rio Preto, Instituto de Medicina Reprodutiva e Fetal, São José do Rio Preto, SP, Brazil.
authors.forename: Antonio Hélio
authors.initials: AH
authors.lastname: Oliani
authors.affiliation: Gynecology and Obstetrics Department, Faculdade de Medicina de São José do Rio Preto, Instituto de Medicina Reprodutiva e Fetal, São José do Rio Preto, SP, Brazil.
authors.forename: Denise Cristina Mós Vaz
authors.initials: DC
authors.lastname: Oliani
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003944:Diagnostic Techniques, Obstetrical and Gynecological; D005260:Female; D006801:Humans; D008875:Middle Aged; D009865:Oocytes; D065851:Ovarian Reserve; D012189:Retrospective Studies; D014463:Ultrasonography; D055815:Young Adult