title: [The state of the nasal mucosa and the paranasal sinuses in the late postoperative period following radical and minimally invasive surgery].
abstract: We have investigated the functional state of the mucous membrane of the nasal cavity and maxillary sinus after radical and minimally invasive surgical procedures during the log-term postoperative period, i.e. three and more months after the intervention. The materials for the study were brushings and histological biopsies; in addition, the functional parameters of the mucous membranes of the nose and maxillary sinuses were estimated before and after surgery. It has been found that the type of the surgical intervention on the inferior turbinate bones for the treatment of chronic rhinitis, such as gentle turbinotomy, has no significant influence on the state of the mucous membrane. The study has demonstrated that 48% of the patients presenting with the chronic maxilloethmoidal mixed form of sinusitis experience epithelial metaplasia resulting in atrophic scarring of the mucosa whereas in the remaining 52% the ciliary epithelium becomes either damaged or detached and the ciliary beat frequency (CBF) decreases. In the exudative form of the disease, CBF and some other functional characteristics are improved but the stromal oedema persists and ciliated epithelium integrity gets compromised.
authors.affiliation: Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997.
authors.forename: M M
authors.initials: MM
authors.lastname: Magomedov
authors.affiliation: Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997.
authors.forename: D F
authors.initials: DF
authors.lastname: Zeynalova
authors.affiliation: Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997.
authors.forename: D V
authors.initials: DV
authors.lastname: Andriyashkin
authors.affiliation: Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997.
authors.forename: N M
authors.initials: NM
authors.lastname: Magomedova
authors.affiliation: Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997.
authors.forename: A E
authors.initials: AE
authors.lastname: Starostina
authors.affiliation: Department of Otorhinolaryngology, N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997.
authors.forename: M V
authors.initials: MV
authors.lastname: Zvereva
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000379:methods; D009079:Mucociliary Clearance; D009297:Nasal Mucosa / Q000473:pathology / Q000503:physiopathology; D059747:Nasal Surgical Procedures / Q000009:adverse effects / Q000379:methods; D010043:Outcome and Process Assessment, Health Care; D011183:Postoperative Complications / Q000473:pathology / Q000503:physiopathology; D011184:Postoperative Period; D012220:Rhinitis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D012426:Russia; D012852:Sinusitis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery