title: Multidetector computer tomography in the pancreatic adenocarcinoma assessment: an update.
abstract: Ductal adenocarcinoma of the pancreas is one of the most aggressive forms of cancer, with only a minority of cases being resectable at the moment of their diagnosis. The accurate detection and characterization of pancreatic carcinoma is very important for patient management. Multidetector-row computed tomography (MDCT) has become the cross-sectional modality of choice in the diagnosis, staging, treatment planning, and follow-up of patients with pancreatic tumors. However, approximately 11% of ductal adenocarcinomas still remain undetected at MDCT because of the lack of attenuation gradient between the lesion and the adjacent pancreatic parenchyma. In this systematic literature review we investigate the current evolution of the CT technique, limitations, and perspectives in the evaluation of pancreatic carcinoma.
authors.affiliation: Department of Diagnostic Imaging, radiant and metabolic Therapy, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Vincenza
authors.initials: V
authors.lastname: Granata
authors.affiliation: Department of Diagnostic Imaging, radiant and metabolic Therapy, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Fusco
authors.affiliation: Department of Diagnostic Imaging, radiant and metabolic Therapy, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Orlando
authors.initials: O
authors.lastname: Catalano
authors.affiliation: Department of Diagnostic Imaging, radiant and metabolic Therapy, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Sergio Venanzio
authors.initials: SV
authors.lastname: Setola
authors.affiliation: Department of Diagnostic Imaging, radiant and metabolic Therapy, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: de Lutio di Castelguidone
authors.affiliation: Department of Hepato-Biliary Surgery, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Piccirillo
authors.affiliation: Department of Hepato-Biliary Surgery, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Palaia
authors.affiliation: Departement of Radiology, Seconda Università degli Studi di Napoli, Naples, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Grassi
authors.affiliation: Departement of Civil and Mechanical Engineering, University of Cassino and Southern Lazio, Lazio, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Granata
authors.affiliation: Department of Hepato-Biliary Surgery, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Izzo
authors.affiliation: Department of Diagnostic Imaging, radiant and metabolic Therapy, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Petrillo
keywords: Dual-source CT; Multidetector computer tomography; Pancreatic adenocarcinoma; Perfusion CT