title: Remodelling germ cells by intercellular cannibalism.
abstract: Work from the early 1980s reported strange lobes protruding from Caenorhabditis elegans germ cell precursors. However, the fate and potential significance of these lobes remained unexplored for decades. Now, neighbouring endodermal cells are shown to sever and digest these lobes, in an unexpected process of 'intercellular cannibalism', which could play an important part in regulating primordial germ cells.
authors.affiliation: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors.forename: Jennifer K
authors.initials: JK
authors.lastname: Heppert
authors.affiliation: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors.forename: Bob
authors.initials: B
authors.lastname: Goldstein
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology; D005110:Extracellular Space / Q000378:metabolism*; D005854:Germ Cells / Q000166:cytology*; D008954:Models, Biological