title: Characterisation of clinical canine meticillin-resistant and meticillin-susceptible Staphylococcus pseudintermedius in France.
abstract: Staphylococcus pseudintermedius is a frequent pathogen in dogs. The emergence of meticillin-resistant S. pseudintermedius (MRSP), which is concomitantly resistant to nearly all veterinary licensed antibiotics used for systemic treatment in dogs, is a major problem for veterinarians. In France, 16.9% (41/243) of the S. pseudintermedius collected in 2010 were MRSP. They mainly belonged to the multiresistant MLST sequence type ST71, spa type t02, SCCmec type II-III (ST71-t02-II-III) European clone. Moreover, we also report the emergence of multiresistant meticillin-susceptible S. pseudintermedius isolates presenting atypical and/or new spa types. This study highlights the need for surveillance, optimised treatment guidelines and new therapeutic alternatives.
authors.affiliation: Agence Nationale de Sécurité Sanitaire (Anses), Unité Antibiorésistance et Virulence Bactériennes, Lyon, France. Electronic address: marisa.haenni@anses.fr.
authors.forename: Marisa
authors.initials: M
authors.lastname: Haenni
authors.affiliation: Agence Nationale de Sécurité Sanitaire (Anses), Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
authors.forename: Natasha Alves
authors.initials: NA
authors.lastname: de Moraes
authors.affiliation: Agence Nationale de Sécurité Sanitaire (Anses), Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Châtre
authors.affiliation: Vebio, Veterinary Laboratory, Arcueil, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Médaille
authors.affiliation: Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Arshnee
authors.initials: A
authors.lastname: Moodley
authors.affiliation: Agence Nationale de Sécurité Sanitaire (Anses), Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Madec
keywords: Antibiotic resistance; Dog; MLST; PFGE; Spa