title: Metabolic imaging for guidance of curative treatment of isolated pelvic implantation metastasis after resection of spontaneously ruptured hepatocellular carcinoma: A case report.
abstract: Spontaneous rupture of hepatocellular carcinoma (HCC) is a life-threatening complication and its prognosis is significantly poor because of the high recurrence rate after initial hepatectomy. Resection of isolated extrahepatic metastasis of HCC has been advocated to obtain a possibility of long-term survival. However, it is a challenge for clinicians to detect implantation metastasis of spontaneously ruptured HCC. Accurate re-staging plays the most important role in making a decision on isolated metastasis resection.18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) is useful in detecting intra-abdominal implantation metastasis from a variety of malignancies and shows superior accuracy to conventional imaging modalities in determining the location of metastasis. We present one patient with a new isolated pelvic implantation metastasis detected by18F-FDG PET/CT and pathologically confirmed by PET/CT-guided percutaneous biopsy, who had a history of resection of spontaneously ruptured HCC two years ago. The patient's condition was stable at the 6-mo follow-up after resection of the isolated pelvic metastasis.
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Hao
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Guo
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Na-Na
authors.initials: NN
authors.lastname: Luo
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Fu
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Hao-Jun
authors.initials: HJ
authors.lastname: Chen
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Long
authors.initials: L
authors.lastname: Zhao
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Wu
authors.affiliation: Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, the First Hospital of Xiamen University, Xiamen 361003, Fujian Province, China.
authors.forename: Long
authors.initials: L
authors.lastname: Sun
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000556:secondary / Q000601:surgery*; D019788:Fluorodeoxyglucose F18; D006498:Hepatectomy; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D009367:Neoplasm Staging; D010386:Pelvic Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery*; D000072078:Positron Emission Tomography Computed Tomography; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D012086:Reoperation; D012422:Rupture, Spontaneous; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Fluorodeoxyglucose; Isolated pelvic implant metastasis; Positron emission tomography/computed tomography; Re-staging; Spontaneously ruptured hepatocellular carcinoma; Surgical resection