title: CEBS: a comprehensive annotated database of toxicological data.
abstract: The Chemical Effects in Biological Systems database (CEBS) is a comprehensive and unique toxicology resource that compiles individual and summary animal data from the National Toxicology Program (NTP) testing program and other depositors into a single electronic repository. CEBS has undergone significant updates in recent years and currently contains over 11 000 test articles (exposure agents) and over 8000 studies including all available NTP carcinogenicity, short-term toxicity and genetic toxicity studies. Study data provided to CEBS are manually curated, accessioned and subject to quality assurance review prior to release to ensure high quality. The CEBS database has two main components: data collection and data delivery. To accommodate the breadth of data produced by NTP, the CEBS data collection component is an integrated relational design that allows the flexibility to capture any type of electronic data (to date). The data delivery component of the database comprises a series of dedicated user interface tables containing pre-processed data that support each component of the user interface. The user interface has been updated to include a series of nine Guided Search tools that allow access to NTP summary and conclusion data and larger non-NTP datasets. The CEBS database can be accessed online at http://www.niehs.nih.gov/research/resources/databases/cebs/.
authors.affiliation: ASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA Isabel.lea@nih.gov.
authors.forename: Isabel A
authors.initials: IA
authors.lastname: Lea
authors.affiliation: ASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA.
authors.forename: Hui
authors.initials: H
authors.lastname: Gong
authors.affiliation: ASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA.
authors.forename: Anand
authors.initials: A
authors.lastname: Paleja
authors.affiliation: ASRCFederal Vistronix, 430 Davis Dr, Suite 260, Morrisville, NC 27569, USA.
authors.forename: Asif
authors.initials: A
authors.lastname: Rashid
authors.affiliation: Division of the National Toxicology Program, National Institute of Environmental Health Sciences, PO Box 12233, Research Triangle Park, NC 27709, USA fostel@niehs.nih.gov.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Fostel
mesh_terms: D016208:Databases, Factual; D030561:Databases, Nucleic Acid; D006801:Humans; D057386:Search Engine; D043922:Toxicogenetics / Q000379:methods; D014116:Toxicology / Q000379:methods; D014584:User-Computer Interface; D064878:Web Browser