title: Increase in CD4+ T-Cell Count at the Time of HIV Diagnosis and Antiretroviral Treatment Initiation Among Persons With HIV in New York City.
abstract: BACKGROUND
  Trends in CD4+T-cell count at human immunodeficiency virus (HIV) infection diagnosis and antiretroviral therapy (ART) initiation can be characterized using laboratory tests from surveillance.
  
  
  METHODS
  We used CD4+T-cell counts and viral loads from New York City for persons who received a diagnosis of HIV infection during 2006-2012.
  
  
  RESULTS
  From 2006 to 2012, the median CD4+T-cell count increased from 325 to 379 cells/µL at diagnosis and from 178 to 360 cells/μL at ART initiation. CD4+T-cell counts were consistently lower in women, blacks, Hispanics, persons who inject drugs, and heterosexuals.
  
  
  CONCLUSIONS
  Increases in CD4+T-cell count at diagnosis and ART initiation suggest that the time from HIV infection to ART initiation has been reduced substantially in New York City.
authors.affiliation: New York City Department of Health and Mental Hygiene.
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Braunstein
authors.affiliation: Institute for Implementation Science in Population Health.|School of Public Health, City University of New York, New York.
authors.forename: McKaylee M
authors.initials: MM
authors.lastname: Robertson
authors.affiliation: New York City Department of Health and Mental Hygiene.
authors.forename: Julie
authors.initials: J
authors.lastname: Myers
authors.affiliation: New York City Department of Health and Mental Hygiene.
authors.forename: Bisrat
authors.initials: B
authors.lastname: Abraham
authors.affiliation: Institute for Implementation Science in Population Health.|School of Public Health, City University of New York, New York.
authors.forename: Denis
authors.initials: D
authors.lastname: Nash
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology* / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009519:New York City; D013997:Time Factors; D019562:Viral Load; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents
keywords: CD4 cell count; HIV; antiretroviral therapy; trends