title: Co-occurrence of a metastatic mammary liposarcoma and an ovarian sex-cord stromal tumor in a dog.
abstract: Sarcoma arising in the mammary gland is a rare tumor in dogs, and primary liposarcoma with metastatic behavior has never been previously reported among canine mammary tumors. A 14-year old female poodle had a mammary mass diagnosed as pleomorphic liposarcoma. Two years following surgical removal, the tumor recurred in the mammary gland with lymph node metastases. In addition, a sex-cord stromal tumor was identified in the ovary. Immunohistochemistry was performed on both tumors that were positive for oestrogen and progesterone receptors. Moreover, the ovarian tumor was positive for calretinin. This is the first report to the authors' knowledge, of the co-occurrence of a pleomorphic liposarcoma of the mammary gland and an ovarian sex-cord stromal (gonadostromal) tumor in the dog.
authors.affiliation: Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Polinas
authors.affiliation: Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
authors.forename: G P
authors.initials: GP
authors.lastname: Burrai
authors.affiliation: Department of Biomedical Sciences, Institute of Pathology, University of Sassari, Via Matteotti 60, 07100 Sassari, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Marras
authors.affiliation: Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Ariu
authors.affiliation: Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
authors.forename: M T
authors.initials: MT
authors.lastname: Zedda
authors.affiliation: Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Pau
authors.affiliation: Department of Veterinary Medicine, University of Sassari, Via Vienna 2, 07100 Sassari, Italy. Electronic address: eantuofermo@uniss.it.
authors.forename: E
authors.initials: E
authors.lastname: Antuofermo
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008080:Liposarcoma / Q000473:pathology / Q000662:veterinary*; D008207:Lymphatic Metastasis; D015674:Mammary Neoplasms, Animal / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000556:secondary / Q000662:veterinary*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000556:secondary / Q000662:veterinary*; D016896:Treatment Outcome
keywords: Dog; Immunohistochemistry; Mammary liposarcoma; Ovarian sex-cord stromal tumor