title: Who Gets Severe Gynecomastia Among HIV-infected Children in the United Kingdom and Ireland?
abstract: There are few data on gynecomastia in HIV-infected children. Within the UK/Ireland's national cohort, 56 of 1873 (3%) HIV-infected children had gynecomastia, of which 10 (0.5%) were severe. All 10 had received antiretroviral therapy for a median of 27.5 (21, 42) months; 4 of 10 had received efavirenz, 7 of 10 and 6 of 10 had received stavudine and/or didanosine respectively. Five were nonreversible, despite changing antiretroviral therapy, and required breast reduction surgery.
authors.affiliation: From the *MRC Clinical Trials Unit at UCL, University College London, London, United Kingdom; and †St. George's Healthcare NHS Trust, London, United Kingdom.
authors.forename: Julia
authors.initials: J
authors.lastname: Kenny
authors.forename: Katja
authors.initials: K
authors.lastname: Doerholt
authors.forename: Di M
authors.initials: DM
authors.lastname: Gibb
authors.forename: Ali
authors.initials: A
authors.lastname: Judd
mesh_terms: D000293:Adolescent; D044966:Anti-Retroviral Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D015331:Cohort Studies; D005260:Female; D006177:Gynecomastia / Q000139:chemically induced / Q000150:complications / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D007494:Ireland / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D044966:Anti-Retroviral Agents