title: [Analysis of clinical factors correlating with osteoporosis in patients with type 2 diabetes mellitus].
abstract: OBJECTIVE
  To analyze the clinical factors that contribute to lowered bone mineral density (BMD) of the lumbar vertebrae in type 2 diabetic patients.
  
  
  METHODS
  Forty type 2 diabetic patients with osteoporosis and 40 age- and gender-matched healthy individuals, selected using propensity score method, were examined for BMD of the L1 to L4 vertebrae and the left femur. Age, gender, course of the disease, body mass index (BMI), fasting blood glucose, serum calcium, serum phosphate, urinary calcium, and urinary phosphate were compared between the two groups.
  
  
  RESULTS
  BMD of the L1 to L4 vertebras was significantly lower in the diabetic group than in the healthy individuals (P<0.05). In the diabetic patients, BMD showed an obvious difference between male and female patients and was negatively correlated with the course of the disease but positively with BMI, fasting blood glucose, urinary calcium and urinary phosphate; BMD was not correlated with age, serum calcium or serum phosphate in these patients.
  
  
  CONCLUSIONS
  Osteoporosis in type 2 diabetic patients is closely related with gender, BMI, course of the disease and poorly controlled glucose level.
authors.affiliation: Department of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.E-mail: zhangyx1979 @126.com.
authors.forename: Yu-Xian
authors.initials: YX
authors.lastname: Zhang
authors.forename: Shao-Xiong
authors.initials: SX
authors.lastname: Min
mesh_terms: D015502:Absorptiometry, Photon; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D015519:Bone Density; D002118:Calcium / Q000097:blood / Q000652:urine; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology; D008297:Male; D010024:Osteoporosis / Q000150:complications*; D010710:Phosphates / Q000097:blood / Q000652:urine
chemical_list: D001786:Blood Glucose; D010710:Phosphates; D002118:Calcium