title: Short-term clinical effect of conformal radiotherapy combined with tegafur gimeracil oteracil potassium in treating recurrent esophagus cancer.
abstract: OBJECTIVE
  To observe clinical effects of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy in the treatment of patients with recurrent esophagus cancer.
  
  
  METHODS
  One hundred and twelve senile patients who suffered from esophagus cancer were selected and randomly divided into two groups, namely, observation group (56 cases) and control group (56 cases). The observation group adopted three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy and the control group adopted three-dimensional conformal radiotherapy only.
  
  
  RESULTS
  All patients completed the treatment, with good compliance. Effective rate of the observation group was 82.1%, which was significantly higher than the control group (67.9%), and the difference was statistically significant (P<0.05). Main toxic and side effects of patients of two groups were radiation esophagitis, gastrointestinal reaction, hematologic toxicities and radiative skin reaction. Differences of incidence rates of all types of toxic and side effects were not statistically significant (P>0.05). The one-year and two-year survival rates of patients of the observation group were 80.4% and 53.6%, respectively, while the control group was 55.4% and 30.4%; differences between two groups were statistically significant (P<0.05).
  
  
  CONCLUSIONS
  Three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy has definite curative effect in treating patients with recurrent esophagus cancer and can improve survival rate of patients, without increasing adverse reaction.
authors.affiliation: Yuyan Jiao, Oncology Dept.(II), Taian City Central Hospital, Shandong, 271000, China.
authors.forename: Yuyan
authors.initials: Y
authors.lastname: Jiao
authors.affiliation: Yuzhen Shen, Oncology Dept.(II), Taian City Central Hospital, Shandong, 271000, China.
authors.forename: Yuzhen
authors.initials: Y
authors.lastname: Shen
authors.affiliation: Hua Yan, Pediatric Surgery Dept., Taian City Central Hospital, Shandong, 271000, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Yan
authors.affiliation: Yan Liu, Dermatology Dept., Taian Maternal and Child Health Care Hospital, Shandong, 271000, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Haihua Tian, Oncology Dept.(II), Taian City Central Hospital, Shandong, 271000, China.
authors.forename: Haihua
authors.initials: H
authors.lastname: Tan
authors.affiliation: Jianzhe Li, Oncology Dept.(II), Taian City Central Hospital, Shandong, 271000, China.
authors.forename: Jianzhe
authors.initials: J
authors.lastname: Li
keywords: Esophagus cancer; Radiotherapy; Tegafur Gimeracil Oteracil Potassium