title: Intravascular hemodynamics and coronary artery disease: New insights and clinical implications.
abstract: Intracoronary hemodynamics play a pivotal role in the initiation and progression of the atherosclerotic process. Low pro-inflammatory endothelial shear stress impacts vascular physiology and leads to the occurrence of coronary artery disease and its implications.
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Marina
authors.initials: M
authors.lastname: Zaromytidou
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Gerasimos
authors.initials: G
authors.lastname: Siasos
authors.affiliation: Mechanical and Industrial Engineering, Northeastern University, Boston, MA, United States.
authors.forename: Ahmet U
authors.initials: AU
authors.lastname: Coskun
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Michelle
authors.initials: M
authors.lastname: Lucier
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Antonios P
authors.initials: AP
authors.lastname: Antoniadis
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Michail I
authors.initials: MI
authors.lastname: Papafaklis
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Konstantinos C
authors.initials: KC
authors.lastname: Koskinas
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Andreou
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
authors.forename: Charles L
authors.initials: CL
authors.lastname: Feldman
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: pstone@partners.org.
authors.forename: Peter H
authors.initials: PH
authors.lastname: Stone
mesh_terms: D057791:Cardiac Imaging Techniques / Q000379:methods; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D013314:Stress, Mechanical
keywords: Acute coronary syndromes; Atherosclerosis; Endothelial shear stress