title: Metal-Free Enantioselective Oxidative Arylation of Alkenes: Hypervalent-Iodine-Promoted Oxidative C-C Bond Formation.
abstract: The enantioselective oxyarylation of (E)-6-aryl-1-silyloxylhex-3-ene was achieved using a lactate-based chiral hypervalent iodine(III) reagent in the presence of boron trifluoride diethyl etherate. The silyl ether promotes the oxidative cyclization, and enhances the enantioselectivity. In addition, the corresponding aminoarylation was achieved.
authors.affiliation: Graduate School of Material Science, University of Hyogo, 3-2-1 Kohto, Kamigori, Hyogo, Japan.
authors.forename: Mio
authors.initials: M
authors.lastname: Shimogaki
authors.affiliation: Graduate School of Material Science, University of Hyogo, 3-2-1 Kohto, Kamigori, Hyogo, Japan.
authors.forename: Morifumi
authors.initials: M
authors.lastname: Fujita
authors.affiliation: Graduate School of Material Science, University of Hyogo, 3-2-1 Kohto, Kamigori, Hyogo, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Sugimura
keywords: cyclization; enantioselectivity; heterocycles; hypervalent compounds; oxidation