title: Differences in clinical presentation and pregnancy outcomes in antepartum preeclampsia and new-onset postpartum preeclampsia: Are these the same disorder?
abstract: OBJECTIVE
  New-onset postpartum preeclampsia is a poorly defined condition that accounts for a significant percentage of eclampsia cases. It is unclear whether new-onset postpartum preeclampsia is a different disorder from or belongs to the same spectrum of classic antepartum preeclampsia. The objective of this study was to compare the clinical presentation and pregnancy outcomes of antepartum preeclampsia and new-onset postpartum preeclampsia.
  
  
  METHODS
  A retrospective study including 92 patients with antepartum preeclampsia and 92 patients with new-onset postpartum preeclampsia was performed. Clinical presentation and pregnancy outcomes were compared. Chi-square test was used to analyze categorical variables, and independentt-test and Mann-WhitneyU-test for numerical variables.P-values of <0.05 were used to indicate statistical signifi cance.
  
  
  RESULTS
  Patients with antepartum preeclampsia and new-onset postpartum preeclampsia differ significantly in profile, symptoms at presentation, laboratory markers and pregnancy outcomes.
  
  
  CONCLUSIONS
  New-onset postpartum preeclampsia has a distinct patient profile and clinical presentation than antepartum preeclampsia, suggesting they may represent different disorders. Characterization of a patient profile with increased risk of developing this condition will help clinicians to identify patients at risk and provide early and targeted interventions to decrease the morbidity associated with this condition.
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University/Hutzel Women's Hospital, Detroit, MI, USA.
authors.forename: Gustavo
authors.identifier: 0000-0002-5796-7074
authors.initials: G
authors.lastname: Vilchez
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University/Hutzel Women's Hospital, Detroit, MI, USA.
authors.forename: Luis R
authors.initials: LR
authors.lastname: Hoyos
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University/Hutzel Women's Hospital, Detroit, MI, USA.
authors.forename: Jocelyn
authors.initials: J
authors.lastname: Leon-Peters
authors.affiliation: Universidad Nacional Federico Villareal, Lima, Peru.
authors.forename: Moraima
authors.initials: M
authors.lastname: Lagos
authors.affiliation: Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Pedro
authors.initials: P
authors.lastname: Argoti
keywords: Postnatal care; Preeclampsia; Pregnancy outcome; Pregnancy-induced hypertension