title: Cardiac Resynchronization Therapy in Women.
abstract: The benefits of cardiac resynchronization therapy (CRT) on the outcomes of patients with heart failure are unquestionable. Women are under-represented in all CRT studies. Most of the available data show that CRT produces a greater clinical benefit in women than men. In several studies, women have left bundle branch block more frequently than men. Women have a remarkably high (90%) CRT response over a wide range of QRS lengths (130-175 milliseconds). Use of a QRS duration of 150 milliseconds as the threshold for CRT prescription may deny a life-saving therapy to many women likely to benefit from CRT.
authors.affiliation: Advocate Heart Institute, Edward Heart Hospital, 4th Floor, 801 South Washington Street, Naperville, IL 60566, USA. Electronic address: mariarosa.Costanzo@advocatehealth.com.
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Costanzo
mesh_terms: D002037:Bundle-Branch Block / Q000628:therapy*; D058406:Cardiac Resynchronization Therapy / Q000379:methods* / Q000706:statistics & numerical data; D019317:Evidence-Based Medicine; D005260:Female; D006333:Heart Failure / Q000628:therapy*; D006801:Humans; D015201:Meta-Analysis as Topic; D064887:Observational Studies as Topic; D016032:Randomized Controlled Trials as Topic; D012727:Sex Characteristics; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: Cardiac resynchronization therapy; Heart failure; Left bundle branch block; Women