title: Laparoscopic Repair for Perforated Peptic Ulcer: A Retrospective Study.
abstract: The incidence of patients presenting with perforated peptic ulcers (PPU) has decreased during the last decades. At the same time, a laparoscopic approach to this condition has been adopted by increased number of surgeons. The aim of this study was to evaluate the early postoperative results of the laparoscopic treatment of perforated peptic ulcer performed in eight Romanian surgical centers with extensive experience in laparoscopic surgery.
  
  
  
  Between 2009 and 2013, 297 patients with perforated peptic ulcer were operated in the eight centers participating in this retrospective study. The patients' charts were reviewed for demographics, surgical procedure, complications and short-term outcomes.
  
  
  
  Boey score of 0 was found in 122 patients (41.1%), Boey 1 in 169 (56.9%), Boey 3 in 6 (2.0%). For 145 (48.8%) patients, primary suture repair was performed, in 146 (49.2%) primary suture repair with omentopexy. There were 6 (2.0%) conversions to open surgery. The operative time was between 25 and 120 min, with a mean of 68 min. Two (0.7%) deaths were noted. Mean hospital stay was 5.5 days, ranges 3-25 days. Postoperative complications included: 7 (2.4%) superficial surgical site infections, 5 (1.6%) cardiovascular, 3 (1.0%) pulmonary, 2 (0.7%) duodenal leakages, 3 (1.0%) deep space infections and 1 (0.3%) upper digestive hemorrhage.
  
  
  
  This study shows that the laparoscopic approach for PPU is feasible; the procedure is safe, with no increased risk of duodenal fistulae or residual intraperitoneal abscesses. We now consider the laparoscopic approach for PPU as the "gold standard" in patients with Boey score 0 or 1.
authors.affiliation: Surgical Clinic 2, Clinical Emergency County Hospital, Victor Babes University of Medicine and Pharmacy, Str. I. Bulbuca, No. 10, Timisoara, Romania. varcus.florian@yahoo.com.
authors.forename: Flore
authors.initials: F
authors.lastname: Vărcuş
authors.affiliation: Surgical Clinic 2, Clinical Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Mircea
authors.initials: M
authors.lastname: Beuran
authors.affiliation: Surgical Clinic 2, Clinical Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Ioan
authors.initials: I
authors.lastname: Lica
authors.affiliation: Surgical Clinic 2, Clinical Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Claudiu
authors.initials: C
authors.lastname: Turculet
authors.affiliation: Onesti City Hospital, Onesti, Romania.
authors.forename: Adrian Valentin
authors.initials: AV
authors.lastname: Cotarlet
authors.affiliation: Surgical Clinic 2, County Emergency Hospital "Sf. Spiridon", Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania.
authors.forename: Stefan
authors.initials: S
authors.lastname: Georgescu
authors.affiliation: Surgical Clinic 2, County Emergency Hospital "Sf. Spiridon", Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania.
authors.forename: Dan
authors.initials: D
authors.lastname: Vintila
authors.affiliation: Surgical Clinic 2, Emergency County Hospital, Victor Papilian Faculty of Medicine, Sibiu, Romania.
authors.forename: Dan
authors.initials: D
authors.lastname: Sabău
authors.affiliation: Surgical Clinic 2, Victor Papilian Faculty of Medicine, Sibiu, Romania.
authors.forename: Alexandru
authors.initials: A
authors.lastname: Sabau
authors.affiliation: Surgical Clinic 1, Emergency County Hospital, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Constantin
authors.initials: C
authors.lastname: Ciuce
authors.affiliation: Surgical Clinic 1, Emergency County Hospital, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Vasile
authors.initials: V
authors.lastname: Bintintan
authors.affiliation: Surgical Clinic 1, County Emergency Hospital, University of Medicine and Pharmacy Craiova, Craiova, Romania.
authors.forename: Eugen
authors.initials: E
authors.lastname: Georgescu
authors.affiliation: Surgical Clinic 2, Emergency County Hospital, Faculty of Medicine, Ovidius University, Constanţa, Romania.
authors.forename: Razvan
authors.initials: R
authors.lastname: Popescu
authors.affiliation: Surgical Clinic 2, Clinical Emergency County Hospital, Victor Babes University of Medicine and Pharmacy, Str. I. Bulbuca, No. 10, Timisoara, Romania.
authors.forename: Cristi
authors.initials: C
authors.lastname: Tarta
authors.affiliation: Surgical Clinic 1, County Emergency Hospital, University of Medicine and Pharmacy Craiova, Craiova, Romania.
authors.forename: Valeriu
authors.initials: V
authors.lastname: Surlin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D061887:Conversion to Open Surgery / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D010535:Laparoscopy; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D010439:Peptic Ulcer Perforation / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D055815:Young Adult