title: The Critical and Multifunctional Roles of Antimicrobial Peptides in Dermatology.
abstract: Antimicrobial peptides are central effector molecules in skin immunology. The functions of antimicrobial peptides in skin diseases include the ability to act as cytokines or growth factors, driving disorders such as psoriasis and rosacea, as well as their action as natural antibiotics to control bacteria that influence diseases such as atopic dermatitis and acne.
authors.affiliation: Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.
authors.forename: Toshiya
authors.initials: T
authors.lastname: Takahashi
authors.affiliation: Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: rgallo@ucsd.edu.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Gallo
mesh_terms: D000152:Acne Vulgaris / Q000378:metabolism* / Q000382:microbiology; D023181:Antimicrobial Cationic Peptides / Q000378:metabolism*; D003876:Dermatitis, Atopic / Q000378:metabolism* / Q000382:microbiology; D006801:Humans; D007249:Inflammation; D011565:Psoriasis / Q000378:metabolism* / Q000382:microbiology; D012393:Rosacea / Q000378:metabolism* / Q000382:microbiology; D012867:Skin / Q000378:metabolism* / Q000382:microbiology; D017192:Skin Diseases, Bacterial / Q000378:metabolism / Q000382:microbiology; D023083:beta-Defensins / Q000378:metabolism; D054804:Cathelicidins
chemical_list: D023181:Antimicrobial Cationic Peptides; D023083:beta-Defensins; D054804:Cathelicidins
keywords: Antimicrobial peptides; Atopic dermatitis; Cathelicidin; Defensins; Immunology; Psoriasis; Rosacea