title: Glucagon like peptide-1 and its receptor agonists: Their roles in management of Type 2 diabetes mellitus.
abstract: This study summarizes major work which investigated the roles of glucagon like peptide-1 (GLP-1) and its receptor (GLP-1R); the use of GLP-1-R agonists and dipeptidyl peptidase 4 inhibitor in the management of type 2 diabetes mellitus. It focuses on the recent therapeutic development which has occurred in this field, and also discusses the potential treatments which can be discovered and implemented in the near future to design an effective therapy for type 2 diabetes mellitus.
authors.affiliation: School of Medicine, University of Tasmania, Hobart, Australia.
authors.forename: Ankit
authors.initials: A
authors.lastname: Gupta
authors.affiliation: School of Community Health, Charles Sturt University, Albury, NSW, Australia.
authors.forename: Herbert F
authors.initials: HF
authors.lastname: Jelinek
authors.affiliation: School of Medicine, University of Tasmania, Hobart, Australia. Electronic address: H.AlAubaidy@utas.edu.au.
authors.forename: Hayder
authors.initials: H
authors.lastname: Al-Aubaidy
mesh_terms: D000595:Amino Acid Sequence; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy* / Q000235:genetics; D019468:Disease Management; D052216:Glucagon-Like Peptide 1 / Q000819:agonists* / Q000502:physiology; D000067757:Glucagon-Like Peptide-1 Receptor / Q000502:physiology; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000097789:Glucagon-Like Peptide-1 Receptor Agonists
chemical_list: D000067757:Glucagon-Like Peptide-1 Receptor; D007004:Hypoglycemic Agents; D052216:Glucagon-Like Peptide 1; D000097789:Glucagon-Like Peptide-1 Receptor Agonists
keywords: Dipeptidyl peptidase inhibitors; Glucagon like peptide-1; Type 2 diabetes mellitus