title: The quest for industrial enzymes from microorganisms.
abstract: Satoshi Ōmura, Professor Emeritus at Kitasato University, was awarded the Nobel Prize for his discovery of a substance of tremendous value to mankind from a microorganism. As a researcher who regularly deals with enzymes produced by microorganisms and a person engaged in microorganism-based business, Professor Ōmura's Nobel Prize fills me with great pride and joy. It is perhaps not surprising that this Nobel Prize-winning research would emerge from Asia, specifically Japan, where people live in harmony with nature rather than try to conquer it. At Amano Enzyme Inc., we devote ourselves to searching for novel enzymes from microorganisms. While incorporating my own experiences, I will recount the stories of a few discoveries of valuable enzyme-producing microbes in soil and bacterial strain libraries. I will also briefly introduce microbial strain library construction as a tool for facilitating the identification of the desired producing bacteria.
authors.affiliation: a Medical Enzymes Division, Amano Enzyme Inc. , Nagoya , Japan.
authors.forename: Shotaro
authors.initials: S
authors.lastname: Yamaguchi
mesh_terms: D001419:Bacteria / Q000378:metabolism*; D004798:Enzymes / Q000096:biosynthesis* / Q000737:chemistry; D007221:Industry; D008958:Models, Molecular; D011487:Protein Conformation; D012988:Soil Microbiology
chemical_list: D004798:Enzymes
keywords: Protein-glutaminase; Transglutaminase; β‐Amylase