title: Effectiveness of Lifestyle Modification in Corrections of States Associated with Metabolic Syndrome.
abstract: In a 3-month study, 30 obese patients were assigned to lifestyle modification therapy, which is the major component of all modern strategies correcting the metabolic syndrome. The 3-month course of non-pharmacological therapy significantly diminished the major index evaluating the state of these patients, i.e., the risk of cardiovascular disasters. This therapy positively affected all the states associated with metabolic syndrome: arterial BP attained the targets in 53% patients together with normalization of their nocturnal arterial BP dipping status; the lipid panel and carbohydrate metabolic indices normalized in 46 and 44% patients, respectively; hepatic steatosis moderated in 56% patients; and the disturbances in hemostasis were annihilated in 67% patients.
authors.affiliation: E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia. viksbest@mail.ru.
authors.forename: S I
authors.initials: SI
authors.lastname: Kseneva
authors.affiliation: E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Borodulina
authors.affiliation: E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia.
authors.forename: O Yu
authors.initials: OY
authors.lastname: Trifonova
authors.affiliation: E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia.|National Research Tomsk State University, Tomsk, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Udut
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D031204:Caloric Restriction / Q000379:methods*; D002318:Cardiovascular Diseases / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology / Q000517:prevention & control; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D015444:Exercise; D005234:Fatty Liver / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D006801:Humans; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D011446:Prospective Studies; D040242:Risk Reduction Behavior; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D014280:Triglycerides
keywords: lifestyle modification; metabolic syndrome; non-pharmacological therapy