title: The Role of Fungi in Atopic Dermatitis.
abstract: There is little doubt that Malassezia spp plays a role in atopic dermatitis because it may interact with the local skin immune responses and barrier function, and sensitization against this skin-colonizing yeast can correlate with disease activity. Also, antifungal therapy shows beneficial effects in some patients. However, the pathogenetic mechanism and mutual interaction between Malassezia spp and atopic dermatitis still remain partly unclear and need further investigation.
authors.affiliation: Allergy Unit, Department of Dermatology, University Hospital of Zurich, Gloriastrasse 31, Zurich 8091, Switzerland; Christine-Kühne Center for Allergy Research and Education CK-CARE, Herman-Burchard-Strasse 1, 7265 Davos Wolfgang, Switzerland. Electronic address: martin.glatz@usz.ch.
authors.forename: Martin
authors.initials: M
authors.lastname: Glatz
authors.affiliation: Mycology Laboratory, Department of Dermatology, University Hospital of Zurich, Gloriastrasse 31, Zurich 8091, Switzerland.
authors.forename: Philipp
authors.initials: P
authors.lastname: Bosshard
authors.affiliation: Allergy Unit, Department of Dermatology, University Hospital of Zurich, Gloriastrasse 31, Zurich 8091, Switzerland; Christine-Kühne Center for Allergy Research and Education CK-CARE, Herman-Burchard-Strasse 1, 7265 Davos Wolfgang, Switzerland.
authors.forename: Peter
authors.initials: P
authors.lastname: Schmid-Grendelmeier
mesh_terms: D000485:Allergens / Q000276:immunology; D000946:Antigens, Fungal / Q000276:immunology; D003876:Dermatitis, Atopic / Q000276:immunology*; D003881:Dermatomycoses / Q000276:immunology; D006801:Humans; D007114:Immunization; D007073:Immunoglobulin E / Q000378:metabolism; D008290:Malassezia / Q000276:immunology*; D012867:Skin / Q000276:immunology* / Q000382:microbiology
chemical_list: D000485:Allergens; D000946:Antigens, Fungal; D007073:Immunoglobulin E
keywords: Atopic dermatitis; Malassezia spp; Sensitization