title: Secondary metabolites from Colletotrichum capsici, an endophytic fungus derived from Siegesbeckia pubescens Makino.
abstract: A rare new tremulane sesquiterpenoid analogue, 11,12-epoxy-5,6-seco-1,6(13)-tremuladien-5,12-olide (1), together with five known altenuene derivatives (2-6) was isolated from the cultures of Colletotrichum capsici, which was isolated as an endophytic fungus from fresh leaves of Siegesbeckia pubescens Makino (Compositae). Their structures were elucidated by means of spectroscopic methods and comparison with literature data. All compounds isolated were reported for the first time from the fungus C. capsici.
authors.affiliation: a Department of Pharmacy , Wuhan First Hospital , Wuhan , China.
authors.forename: Fuqian
authors.initials: F
authors.lastname: Wang
authors.affiliation: a Department of Pharmacy , Wuhan First Hospital , Wuhan , China.
authors.forename: Haoran
authors.initials: H
authors.lastname: Ma
authors.affiliation: b Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College , Huazhong University of Science and Technology , Wuhan , China.
authors.forename: Zhengxi
authors.initials: Z
authors.lastname: Hu
authors.affiliation: a Department of Pharmacy , Wuhan First Hospital , Wuhan , China.
authors.forename: Jie
authors.initials: J
authors.lastname: Jiang
authors.affiliation: b Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College , Huazhong University of Science and Technology , Wuhan , China.
authors.forename: Hucheng
authors.initials: H
authors.lastname: Zhu
authors.affiliation: a Department of Pharmacy , Wuhan First Hospital , Wuhan , China.
authors.forename: Lu
authors.initials: L
authors.lastname: Cheng
authors.affiliation: a Department of Pharmacy , Wuhan First Hospital , Wuhan , China.
authors.forename: Quanwei
authors.initials: Q
authors.lastname: Yang
authors.affiliation: a Department of Pharmacy , Wuhan First Hospital , Wuhan , China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.affiliation: a Department of Pharmacy , Wuhan First Hospital , Wuhan , China.
authors.forename: Geng
authors.initials: G
authors.lastname: Zhang
authors.affiliation: b Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College , Huazhong University of Science and Technology , Wuhan , China.
authors.forename: Yonghui
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D019659:Asteraceae / Q000382:microbiology*; D020231:Colletotrichum / Q000737:chemistry / Q000378:metabolism*; D060026:Endophytes / Q000737:chemistry / Q000378:metabolism; D007783:Lactones / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018515:Plant Leaves / Q000382:microbiology; D064210:Secondary Metabolism; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism
chemical_list: C000625954:11,12-epoxy-5,6-seco-1,6(13)-tremuladien-5,12-olide; D007783:Lactones; D012717:Sesquiterpenes; C040005:altenuene
keywords: Colletotrichum capsici; Endophytic fungus; tremulane sesquiterpenoid