title: Clinical Complete Response from Chemotherapy in an Elderly Patient with Metastatic Gastric Cancer: A Case Report.
abstract: An 81-year-old man was admitted with upper abdominal pain and weight loss. Esophagogastroduodenoscopy revealed a large tumor located from the gastric angle to the body. Histological analysis of a biopsy revealed a moderately differentiated adenocarcinoma. Computed tomography revealed metastases in the liver and lung and the patient was subsequently diagnosed with metastatic advanced gastric cancer. He was treated with chemotherapy using S-1 (80 mg/m2) and cisplatin (CDDP) (60 mg/m2). Twenty-two months after chemotherapy, the gastric tumor, and the nodules in the liver and lung, had disappeared. We subsequently diagnosed a clinical complete response. The patient was treated with further S-1 monotherapy for 7 months after complete response assessment. He has lived for more than 7 years since the initial diagnosis without recurrence. Chemotherapy using S-1 and CDDP may be a potent strategy for improving survival in elderly patients with advanced gastric cancer.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Nippon Medical School.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Kawagoe
authors.forename: Yuta
authors.initials: Y
authors.lastname: Maruki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nagoya
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kosugi
authors.forename: Teppei
authors.initials: T
authors.lastname: Akimoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamawaki
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Kodaka
authors.forename: Mayumi
authors.initials: M
authors.lastname: Shimpuku
authors.forename: Nobue
authors.initials: N
authors.lastname: Ueki
authors.forename: Seiji
authors.initials: S
authors.lastname: Futagami
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Miyake
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Iwakiri
mesh_terms: D000369:Aged, 80 and over; D016145:Endoscopy, Digestive System; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome