title: Olive oil and postprandial hyperlipidemia: implications for atherosclerosis and metabolic syndrome.
abstract: Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in health status, as measured by reduced mortality from several chronic diseases. The current pandemic of obesity, metabolic syndrome, and type 2 diabetes is intimately associated with an atherogenic dyslipidemic phenotype. The core components of the dyslipidemia of the metabolic syndrome, which most likely initiate atherosclerosis, are the "lipid triad" consisting of high plasma triglycerides, low levels of high-density lipoproteins, and a preponderance of small, dense low-density lipoproteins at fasting. However, postprandial (non-fasting) TGs (postprandial hyperlipidemia) are also recognized as an important component for atherosclerosis. Herein, the purpose of this review was to provide an update on the effects and mechanisms related to olive oil on postprandial hyperlipidemia and its implications for the onset and progression of atherosclerosis and metabolic syndrome.
authors.affiliation: Laboratory of Cellular and Molecular Nutrition, Instituto de la Grasa, CSIC. Ctra. de Utrera Km. 1, 41013 Seville, Spain. delapaz@us.es.
authors.forename: Sergio
authors.initials: S
authors.lastname: Montserrat-de la Paz
authors.affiliation: Department of Cell Biology, Faculty of Biology, University of Seville. C/ Professor Garcia Gonzalez s/n, 41012 Seville, Spain.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Bermudez
authors.affiliation: Laboratory of Cellular and Molecular Nutrition, Instituto de la Grasa, CSIC. Ctra. de Utrera Km. 1, 41013 Seville, Spain. delapaz@us.es.
authors.forename: Magdalena P
authors.initials: MP
authors.lastname: Cardelo
authors.affiliation: Laboratory of Cellular and Molecular Nutrition, Instituto de la Grasa, CSIC. Ctra. de Utrera Km. 1, 41013 Seville, Spain. delapaz@us.es.
authors.forename: Sergio
authors.initials: S
authors.lastname: Lopez
authors.affiliation: Laboratory of Cellular and Molecular Nutrition, Instituto de la Grasa, CSIC. Ctra. de Utrera Km. 1, 41013 Seville, Spain. delapaz@us.es.
authors.forename: Rocio
authors.initials: R
authors.lastname: Abia
authors.affiliation: Laboratory of Cellular and Molecular Nutrition, Instituto de la Grasa, CSIC. Ctra. de Utrera Km. 1, 41013 Seville, Spain. delapaz@us.es.
authors.forename: Francisco J G
authors.initials: FJ
authors.lastname: Muriana
mesh_terms: D050197:Atherosclerosis / Q000517:prevention & control*; D038441:Diet, Mediterranean; D006801:Humans; D006943:Hyperglycemia; D024821:Metabolic Syndrome / Q000517:prevention & control*; D000069463:Olive Oil / Q000494:pharmacology*
chemical_list: D000069463:Olive Oil