title: Neurobiology as Information Physics.
abstract: This article reviews thermodynamic relationships in the brain in an attempt to consolidate current research in systems neuroscience. The present synthesis supports proposals that thermodynamic information in the brain can be quantified to an appreciable degree of objectivity, that many qualitative properties of information in systems of the brain can be inferred by observing changes in thermodynamic quantities, and that many features of the brain's anatomy and architecture illustrate relatively simple information-energy relationships. The brain may provide a unique window into the relationship between energy and information.
authors.affiliation: Department of Cellular Biology, Franklin College of Arts and Sciences, University of Georgia, Athens GA, USA.
authors.forename: Sterling
authors.initials: S
authors.lastname: Street
keywords: Bekenstein bound; Landauer limit; free energy principle; information thermodynamics; optimization