title: Evaluation of the antimicrobial activity of daptomycin and linezolid against vancomycin-resistant Enterococcus spp. isolates in south India.
abstract: Vancomycin-resistant enterococci (VRE) have emerged as a major nosocomial pathogen. Alternatives for the treatment of infection with VRE include linezolid and daptomycin. Experience with these agents, especially daptomycin, is limited in India. The minimum inhibitory concentration of linezolid and daptomycin against 98 clinical isolates of VRE was tested by E-test. Daptomycin and linezolid showed good activity, with susceptibility rates of 93.9% and 96.9%, respectively.
authors.affiliation: Department of Clinical Microbiology, Christian Medical College, Vellore 632004, India.
authors.forename: Shakti
authors.initials: S
authors.lastname: Laishram
authors.affiliation: Department of Clinical Microbiology, Christian Medical College, Vellore 632004, India.
authors.forename: Rani D
authors.initials: RD
authors.lastname: Sahni
authors.affiliation: Department of Clinical Microbiology, Christian Medical College, Vellore 632004, India.
authors.forename: Shalini
authors.initials: S
authors.lastname: Anandan
authors.affiliation: Department of Clinical Microbiology, Christian Medical College, Vellore 632004, India. Electronic address: vbalaji@cmcvellore.ac.in.
authors.forename: Veeraragavan
authors.initials: V
authors.lastname: Balaji
keywords: Daptomycin; Enterococcus spp.; Linezolid; Vancomycin-resistant enterococci