title: Hereditary angioedema (HAE): a cause for recurrent abdominal pain.
abstract: A 44-year-old Hispanic woman presented to the emergency room with a 2-day history of sudden onset of severe cramping left lower quadrant abdominal pain associated with ∼20 episodes diarrhoea. Abdominal CT scan exhibited bowel wall oedema and acute extensive colitis. On the basis of the preliminary diagnosis of acute abdomen, the patient was admitted under the surgical team and treated for acute colitis. Since her family history was significant for hereditary angioedema (HAE), complement studies were performed which revealed low complement C4 levels and abnormally low values of C1q esterase inhibitor. Thus, the diagnosis of HAE type I was established. This case report summarises that the symptoms of HAE are often non-specific, hence making the underlying cause difficult to diagnose.
authors.affiliation: Department of Internal Medicine, Maimonides Medical Center, Brooklyn, New York, USA.
authors.forename: Parita
authors.initials: P
authors.lastname: Soni
authors.affiliation: Department of Internal Medicine, Maimonides Medical Center, Brooklyn, New York, USA.
authors.forename: Vivek
authors.initials: V
authors.lastname: Kumar
authors.affiliation: Department of Internal Medicine, Maimonides Medical Center, Brooklyn, New York, USA.
authors.forename: Samson
authors.initials: S
authors.lastname: Alliu
authors.affiliation: Department of Cardiology, Maimonides Medical Center, Brooklyn, New York, USA.
authors.forename: Vijay
authors.initials: V
authors.lastname: Shetty
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology*; D000328:Adult; D003181:Complement C4 / Q000378:metabolism; D003967:Diarrhea / Q000209:etiology; D005260:Female; D056829:Hereditary Angioedema Types I and II / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D012008:Recurrence
chemical_list: D003181:Complement C4