title: The BALB/c mouse infection model for improving the Haemophilus parasuis serotyping scheme.
abstract: The use of BALB/c mouse as an alternative model to study Haemophilus parasuis (HPS) infections was evaluated, supplying the serotyping scheme by comparing the pathogenicity of different serovar HPS in pigs and mice challenge using statistical analysis. Results showed that the pathogenicity of different serovar HPS in mouse was consistent with in pigs, proving that this model is a viable alternative to pigs. It provides a convenient methodology for determining the virulence of HPS strains.
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Yu
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Yuyu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Yijun
authors.initials: Y
authors.lastname: Du
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Baohua
authors.initials: B
authors.lastname: Huang
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Wenbo
authors.initials: W
authors.lastname: Sun
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Cong
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China; College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
authors.forename: Jun
authors.initials: J
authors.lastname: Peng
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Sufang
authors.initials: S
authors.lastname: Ren
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Lihui
authors.initials: L
authors.lastname: Gou
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Jianli
authors.initials: J
authors.lastname: Shi
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Jianda
authors.initials: J
authors.lastname: Li
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China. Electronic address: wujiaqiang2000@sina.com.
authors.forename: Jiaqiang
authors.initials: J
authors.lastname: Wu
authors.affiliation: Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China. Electronic address: wangjb@saas.ac.cn.
authors.forename: Jinbao
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D005260:Female; D006192:Haemophilus Infections / Q000662:veterinary* / Q000821:virology; D044137:Haemophilus parasuis / Q000145:classification / Q000472:pathogenicity* / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D023421:Models, Animal; D065288:Serogroup; D012703:Serotyping / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000821:virology*; D014774:Virulence
keywords: BALB/c mouse; Haemophilus parasuis; Model