title: Stimulation of Protein Expression Through the Harmonic Resonance of Frequency-Specific Music.
abstract: OBJECTIVE
  The use of specific frequencies for specific individual amino acids may increase the potential energy of protein molecules in the medium [1]. The resonance would also increase the movement of particles in the cytosol, increasing the collisions necessary for the conduction of protein expression.
  
  
  METHODS
  The clash of two waves that share frequencies will exhibit an increase in energy through an increase in amplitude [2]. The increase in energy would in turn increase the number of collisions forming the tRNA-amino acid, increasing the amino acid acquiry for ribosomes to improve intracellular efficiency in gene expression. To test the hypothesis, Red Fluorescent Protein (RFP) in transformated BL-21 strains of E. coli and p53 protein of MCF-7 were examined after exposure to sounds of specific frequencies.
  
  
  RESULTS
  Through the exposure of the experimental systems to a sequence of sounds that match the frequencies of specific amino acids, the levels of RFP exhibition respective to the control groups in the bacterial medium increased two-fold in terms of RFU. The experiments that targeted the p53 protein with the 'music' showed a decrease in the cell prevalence in the MCF-7 type breast cancer cells by 28%, by decreasing the speed of tumour formation.
  
  
  CONCLUSIONS
  Exposure to 'music' that was designed through assigning a musical note for every single one of the twenty unique amino acids, produced both an analytical and a visible shift in protein synthesis, making it as potential tool for reducing procedural time uptake.
authors.affiliation: . w207725797@student.hccs.edu.
authors.forename: Ibrahim Y
authors.initials: IY
authors.lastname: Orhan
authors.forename: Burak A
authors.initials: BA
authors.lastname: Gulbahar
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D045744:Cell Line, Tumor; D003600:Cytosol / Q000378:metabolism*; D004926:Escherichia coli / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D008164:Luminescent Proteins / Q000378:metabolism; D061986:MCF-7 Cells; D009146:Music; D014176:Protein Biosynthesis; D012343:RNA, Transfer / Q000737:chemistry; D013997:Time Factors; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism; D000097573:Red Fluorescent Protein
chemical_list: D000596:Amino Acids; D008164:Luminescent Proteins; D012343:RNA, Transfer; D016159:Tumor Suppressor Protein p53; D000097573:Red Fluorescent Protein; C495901:TP53 protein, human