title: Isolation and characterization of two new 2-isobutylmalates from Bletilla striata.
abstract: The present study isolated 17 compounds from the tubers of Bletilla striata (Orchidaceae), using various chromatographic techniques. Their structures were identified based on their physical-chemical properties and spectroscopic analyses. Among them, two new 2-isobutylmalates, named bletimalates A (1) and B (2), together with other fifteen known compounds (3-17), were isolated and identified. Additionally, compounds 3, 4, and 8 were isolated from this plant for the first time.
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China.
authors.forename: Huan-Yu
authors.initials: HY
authors.lastname: Guan
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Guizhou Provincial People's Hospital, Guiyang 550004, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
authors.forename: Yong-Lin
authors.initials: YL
authors.lastname: Wang
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China.
authors.forename: Ai-Min
authors.initials: AM
authors.lastname: Wang
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China.
authors.forename: Jun-Hong
authors.initials: JH
authors.lastname: Liu
authors.affiliation: Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China.
authors.forename: Xun
authors.initials: X
authors.lastname: He
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China.
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Li
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Ministry of Education, Guiyang 550004, China. Electronic address: lshangg@163.com.
authors.forename: Shang-Gao
authors.initials: SG
authors.lastname: Liao
mesh_terms: D008293:Malates / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D029595:Orchidaceae / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D035281:Plant Tubers / Q000737:chemistry
chemical_list: D008293:Malates; D010936:Plant Extracts
keywords: 2-Isobutylmalates; Bletilla striata; Chemical constituents