title: Utility of real-time prospective motion correction (PROMO) on 3D T1-weighted imaging in automated brain structure measurements.
abstract: PROspective MOtion correction (PROMO) can prevent motion artefacts. The aim of this study was to determine whether brain structure measurements of motion-corrected images with PROMO were reliable and equivalent to conventional images without motion artefacts. The following T1-weighted images were obtained in healthy subjects: (A) resting scans with and without PROMO and (B) two types of motion scans ("side-to-side" and "nodding" motions) with and without PROMO. The total gray matter volumes and cortical thicknesses were significantly decreased in motion scans without PROMO as compared to the resting scans without PROMO (p < 0.05). Conversely, Bland-Altman analysis indicated no bias between motion scans with PROMO, which have good image quality, and resting scans without PROMO. In addition, there was no bias between resting scans with and without PROMO. The use of PROMO facilitated more reliable brain structure measurements in subjects moving during data acquisition.
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan.
authors.forename: Keita
authors.initials: K
authors.lastname: Watanabe
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan.
authors.forename: Shingo
authors.initials: S
authors.lastname: Kakeda
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan.
authors.forename: Natsuki
authors.initials: N
authors.lastname: Igata
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan.
authors.forename: Rieko
authors.initials: R
authors.lastname: Watanabe
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan.
authors.forename: Hidekuni
authors.initials: H
authors.lastname: Narimatsu
authors.affiliation: MR Applications and Workflow Asia Pacific, GE Healthcare, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nozaki
authors.affiliation: MR Applications and Workflow, GE Healthcare, Rochester, MN, USA.
authors.lastname: Dan Rettmann
authors.affiliation: Department of Radiology, Nihon University School of Medicine, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Abe
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Japan.
authors.forename: Yukunori
authors.initials: Y
authors.lastname: Korogi
mesh_terms: D000328:Adult; D000465:Algorithms; D016477:Artifacts; D002540:Cerebral Cortex / Q000000981:diagnostic imaging* / Q000502:physiology; D005260:Female; D066128:Gray Matter / Q000000981:diagnostic imaging* / Q000502:physiology; D019416:Head Movements / Q000502:physiology; D064368:Healthy Volunteers; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity