title: Successful Single-Lung Transplant for Severe Lung Graft-Versus-Host Disease Two Years After Sibling Allograft for Acute Lymphoblastic Leukemia: A Case Report.
abstract: Bone marrow transplantation (BMT) has been performed as a successful life-saving treatment for hematological and neoplastic diseases. Despite the predictable long-term survival rates in BMT, pulmonary complications reduce the survival rates significantly mainly because of chronic graft-versus-host disease (GVHD). This report briefly discusses a successful lung transplantation case for severe lung GVHD after allograft for acute lymphoblastic leukemia. This case report supports the scarce evidence in the literature for the importance of lung transplantation as a therapeutic option for patients who develop respiratory failure secondary to BMT.
authors.affiliation: Cell & Tissue Therapies WA, Royal Perth Hospital, Faculty of Medicine, Dentistry, and Health Sciences, University of Western Australia, Perth, WA, Australia.
authors.forename: M R
authors.initials: MR
authors.lastname: Irhimeh
authors.affiliation: Department of Respiratory Medicine, Advanced Lung Diseases Unit, Fiona Stanley Hospital, Perth, WA, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Musk
authors.affiliation: Department of Hematology, Fiona Stanley Hospital, and Faculty of Medicine, Dentistry, and Health Sciences, University of Western Australia, Perth, WA, Australia. Electronic address: julian.cooney@health.wa.gov.au.
authors.forename: J P
authors.initials: JP
authors.lastname: Cooney
mesh_terms: D000293:Adolescent; D000328:Adult; D064591:Allografts; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology / Q000601:surgery*; D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000601:surgery*; D035781:Siblings; D014184:Transplantation, Homologous / Q000009:adverse effects