title: Adalimumab and Non-Arteritic Anterior Ischaemic Optic Neuropathy: A Case Report.
abstract: Sequential anterior ischaemic optic neuropathy was observed in a patient treated with a tumour necrosis factor α (TNF) inhibitor, adalimumab, for ankylosing spondylitis. He developed decreased visual acuity in the right eye after 17 months of treatment. Findings showed right optic disc oedema with haemorrhages and visual field defect. Adalimumab was discontinued and vision stabilised. After restarting adalimumab, he developed optic neuropathy in the left eye. Findings showed optic disc oedema, with haemorrhages and visual field changes in the left eye. Adalimumab may be associated with optic neuropathy; providers prescribing TNF inhibitors should be aware of optic neuropathy as a potential complication.
authors.affiliation: Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah Salt Lake City, Utah USA.
authors.forename: Krista
authors.initials: K
authors.lastname: Kinard
authors.affiliation: Department of Internal Medicine (Rheumatology Division), University of Utah Salt Lake City, Utah USA.
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Walsh
authors.affiliation: Department of Internal Medicine (Rheumatology Division), University of Utah Salt Lake City, Utah USA.
authors.forename: Gopi K
authors.initials: GK
authors.lastname: Penmetsa
authors.affiliation: Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah Salt Lake City, Utah USA.
authors.forename: Judith E A
authors.initials: JE
authors.lastname: Warner
keywords: Adalimumab; anterior ischaemic optic neuropathy; drugs; optic nerve; pharmacology