title: Susceptibility of Rubella Among Pregnant Women Attending the Antenatal Clinic in a Tertiary Care Hospital, Jabalpur, Central India.
abstract: The purpose of this study was to evaluate rubella susceptibility of pregnant women from central India as rubella infection can be devastating for the newborn if it occurs in the mother in the first trimester of pregnancy, which may lead to congenital rubella syndrome (CRS). There are very few studies about seroprevalence of rubella from India and none from central India. The study was conducted among women attending the obstetric department of a tertiary care hospital, in which 369 antenatal cases were tested for the presence of immunoglobulin G antibody for rubella and its titer. Data were analyzed using statistical tests. A total of 141 (38.2%) women were found susceptible to rubella. There was no significant difference in rubella susceptibility among different socioeconomic classes, ages, and gravidity. A large proportion of pregnant women were found to be rubella susceptible, posing immense threat of CRS to their newborns. A robust program for rubella immunization targeting young adult women is needed to avoid CRS.
authors.affiliation: 1 National Institute for Research in Tribal Health , Indian Council of Medical Research, Jabalpur, India .
authors.forename: Bhupesh K
authors.initials: BK
authors.lastname: Kori
authors.affiliation: 2 Netaji Subhash Chandra Bose Medical College , Jabalpur, India .
authors.forename: Kavita N
authors.initials: KN
authors.lastname: Singh
authors.affiliation: 1 National Institute for Research in Tribal Health , Indian Council of Medical Research, Jabalpur, India .
authors.forename: Ravendra K
authors.initials: RK
authors.lastname: Sharma
authors.affiliation: 1 National Institute for Research in Tribal Health , Indian Council of Medical Research, Jabalpur, India .
authors.forename: Bhagwati S
authors.initials: BS
authors.lastname: Sharma
authors.affiliation: 2 Netaji Subhash Chandra Bose Medical College , Jabalpur, India .
authors.forename: Poorva
authors.initials: P
authors.lastname: Badkur
authors.affiliation: 1 National Institute for Research in Tribal Health , Indian Council of Medical Research, Jabalpur, India .
authors.forename: Pradip V
authors.initials: PV
authors.lastname: Barde
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D003430:Cross-Sectional Studies; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007194:India; D011247:Pregnancy; D037841:Pregnant People; D011295:Prenatal Care; D012409:Rubella / Q000276:immunology*; D016036:Seroepidemiologic Studies; D062606:Tertiary Care Centers; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G
keywords: central India; pregnant women; rubella susceptibility