title: Saturation-inversion-recovery: A method for T1measurement.
abstract: Spin-lattice relaxation (T1) has always been measured by inversion-recovery (IR), saturation-recovery (SR), or related methods. These existing methods share a common behavior in that the function describing T1sensitivity is the exponential, e.g., exp(-τ/T1), where τ is the recovery time. In this paper, we describe a saturation-inversion-recovery (SIR) sequence for T1measurement with considerably sharper T1-dependence than those of the IR and SR sequences, and demonstrate it experimentally. The SIR method could be useful in improving the contrast between regions of differing T1in T1-weighted MRI.
authors.affiliation: Shanghai University of Medicine and Health Science, Shanghai 201318, China; Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai 200062, China; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA. Electronic address: wanghzhi2000@sina.com.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Wang
authors.affiliation: Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA; Department of Physics, University of Massachusetts Lowell, Lowell, MA 01854, USA.
authors.forename: Ming
authors.initials: M
authors.lastname: Zhao
authors.affiliation: Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA; Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Jerome L
authors.initials: JL
authors.lastname: Ackerman
authors.affiliation: Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA; Schlumberger-Doll Research, Cambridge, MA 02143, USA.
authors.forename: Yiqiao
authors.initials: Y
authors.lastname: Song
mesh_terms: D000465:Algorithms; D004574:Electromagnetic Fields; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D059629:Signal-To-Noise Ratio; D013055:Spectrophotometry, Infrared; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water
keywords: Saturation inversion recovery; Spin-lattice relaxation; T(1) contrast; T(1) dispersion