title: MULTICOMPONENT REACTIONS IN ALKALOID-BASED DRUG DISCOVERY.
abstract: Multicomponent reactions are emerging as a powerful tool in alkaloid-based drug discovery. This Highlight describes several recent (all published in 2011) examples of the employment of multicomponent reactions for the synthesis of biologically active alkaloids and their medicinally relevant analogues.
authors.affiliation: New Mexico Institute of Mining and Technology, 801 Leroy Place, Socorro, New Mexico 87801, USA.
authors.forename: I V
authors.initials: IV
authors.lastname: Magedov
authors.affiliation: New Mexico Institute of Mining and Technology, 801 Leroy Place, Socorro, New Mexico 87801, USA.
authors.forename: A
authors.initials: A
authors.lastname: Kornienko
keywords: alkaloid; cyanocycline A; drug discovery; luotonin; multicomponent reactions; rigidin; tubulysin