title: Medical and Surgical Advances in Intracerebral Hemorrhage and Intraventricular Hemorrhage.
abstract: In recent decades, the medical and surgical treatment of intracerebral hemorrhage (ICH) have become the focus of a number of scientific investigations. This effort has been led by an international group of neurologists and neurosurgeons with the goal of studying functional recovery and developing new medical and surgical treatments to facilitate improved clinical outcomes. Currently, two of the most pressing ICH investigational goals are (1) early blood pressure control, and (2) safe hematoma volume reduction. Answering these questions would support decision-making, level-of-care choices, and the global research strategy of developing biologically informed treatments. The authors review the contemporary medical management and the conventional and minimally invasive surgical approaches to spontaneous ICH, as well as discuss the scope of the problem, recent clinical trials, management issues, and relevant questions for future research. They propose the hypothesis that strategies using minimally invasive techniques, including clot aspiration with stereotactic guidance, may give better results with improved clinical outcomes compared with standard open surgical approaches. They also discuss the level of evidence for the variously known approaches.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Neurology and Neurosurgery, Johns Hopkins University, Baltimore, Maryland.
authors.forename: Wendy
authors.initials: W
authors.lastname: Ziai
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Neurology and Neurosurgery, Johns Hopkins University, Baltimore, Maryland.
authors.forename: J Ricardo
authors.initials: JR
authors.lastname: Carhuapoma
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Neurology, Neurosurgery, and General Internal Medicine, Johns Hopkins University, Baltimore, Maryland.
authors.forename: Paul
authors.initials: P
authors.lastname: Nyquist
authors.affiliation: Division of Brain Injury Outcomes, Department of Neurology, Johns Hopkins University, Baltimore, Maryland.
authors.forename: Daniel F
authors.initials: DF
authors.lastname: Hanley
mesh_terms: D002543:Cerebral Hemorrhage / Q000601:surgery*; D006801:Humans; D020127:Recovery of Function