title: Management of children with congenital heart defect: state of the art and future prospects.
abstract: The treatment of children with congenital heart defects has evolved in the last 60 years from conservative care to a highly specialized management where advances in imaging, surgical, interventional and support techniques meet together to ensure satisfactory development and good quality of life to the child and to the upcoming grown up. Management of congenital heart defects best begins before birth with the aim, whenever possible, to maintain or establish biventricular physiology or, if this is excluded, to optimize the conditions for univentricular physiology. Current research in the field of genetics, device bioengineering and miniaturization, stem cell therapy, and fusion imaging technology is expected to help to improve further patient outcome. In this review, current management strategies and future prospects are discussed.
authors.affiliation: Department of Pediatrics-Pediatric Cardiology, University Hospital Liège, Rue de Gaillarmont 600, B. 4032 Liège, Belgium.
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Seghaye
mesh_terms: D000293:Adolescent; D035843:Biomedical Research / Q000639:trends; D002309:Cardiology / Q000639:trends; D002648:Child; D046128:Fetal Therapies; D005544:Forecasting; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011788:Quality of Life; D016216:Ultrasonography, Prenatal; D066253:Vascular Remodeling; D016276:Ventricular Function / Q000502:physiology
keywords: cardiac surgery; catheter interventions; congenital heart defects; future directions; pediatric; prenatal diagnosis