title: [Three Years Follow-up Study after Refractive Small Incision Lenticule Extraction (SMILE) Using 500 kHz Femtosecond Laser in "Fast Mode"].
abstract: BackgroundThe aim of this clinical trial was to check the results of laser built-in settings 3 years after ReLEx SMILE for moderate and high myopia in unselected "real life" patients.Patients and Methods50 myopic eyes of 27 patients were called in for examination after 3 years. 25 of these eyes with a preoperative myopia under - 6D comprised the "moderate myopia subgroup". All surgeries were performed with the 500 kHz VisuMax® femtosecond laser (Carl Zeiss Meditec AG, Jena) in the "fast mode" setting.ResultsThe spherical equivalent (SE) of the entire group changed from - 6.18 D (± 1.91) prior to surgery to - 0.18 D (± 0.39) 3 years later. The preoperative SE in the moderate myopia subgroup changed from - 4.71 D (± 0.94) to - 0.04 D (± 0.23). 14 % of 50 eyes gained one line and 22 % lost one line of CDVA. The regression between month 3 and 36 was 0.07D for the entire group and 0.06 D for the moderate myopia subgroup. There were no late side effects. Primary undercorrection was predominantly seen in eyes over - 6 D.ConclusionReLEx SMILE shows remarkable stability over the entire range of myopias after 3 years, however primary undercorrection occurs predominantly in eyes of - 6.0 D, which necessitates nomogram adjustment.
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg.
authors.forename: A
authors.initials: A
authors.lastname: Messerschmidt-Roth
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg.
authors.forename: W
authors.initials: W
authors.lastname: Sekundo
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg.
authors.forename: A
authors.initials: A
authors.lastname: Lazaridis
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg.
authors.forename: S
authors.initials: S
authors.lastname: Schulze
mesh_terms: D000328:Adult; D048988:Corneal Surgery, Laser / Q000009:adverse effects / Q000379:methods*; D019317:Evidence-Based Medicine; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D009216:Myopia / Q000175:diagnosis* / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D015995:Prevalence; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult