title: Predictors and in-hospital prognosis of recurrent acute myocardial infarction.
abstract: OBJECTIVE
  To investigate the contributing factors and in-hospital prognosis of patients with or without recurrent acute myocardial infarction (AMI).
  
  
  METHODS
  A total of 1686 consecutive AMI patients admitted to Peking University People's Hospital from January 2010 to December 2015 were recruited. Their clinical characteristics were retrospectively compared between patients with or without a recurrent AMI. Then multivariable logistic regression was used to estimate the predictors of recurrent myocardial infarction.
  
  
  RESULTS
  Recurrent AMI patients were older (69.3 ± 11.5vs. 64.7 ± 12.8 years,P< 0.001) and had a higher prevalence of diabetes mellitus (DM) (52.2%vs. 35.0%,P< 0.001) compared with incident AMI patients, they also had worse heart function at admission, more severe coronary disease and lower reperfusion therapy. Age (OR = 1.03, 95% CI: 1.02-1.05;P< 0.001), DM (OR = 1.86, 95% CI: 1.37-2.52;P< 0.001) and reperfusion therapy (OR = 0.74; 95% CI: 0.52-0.89;P< 0.001) were independent risk factors for recurrent AMI. Recurrent AMI patients had a higher in-hospital death rate (12.1%vs. 7.8%,P= 0.039) than incident AMI patients.
  
  
  CONCLUSIONS
  Recurrent AMI patients presented with more severe coronary artery conditions. Age, DM and reperfusion therapy were independent risk factors for recurrent AMI, and recurrent AMI was related with a high risk of in-hospital death.
authors.affiliation: Department of Cardiology, Peking University People's Hospital, Beijing, China; Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People's Hospital, Beijing, China; Center for Cardiovascular Translational Research, Peking University People's Hospital, Beijing, China.
authors.forename: Cheng-Fu
authors.initials: CF
authors.lastname: Cao
authors.affiliation: Department of Cardiology, Peking University People's Hospital, Beijing, China; Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People's Hospital, Beijing, China; Center for Cardiovascular Translational Research, Peking University People's Hospital, Beijing, China.
authors.forename: Su-Fang
authors.initials: SF
authors.lastname: Li
authors.affiliation: Department of Cardiology, Peking University People's Hospital, Beijing, China; Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People's Hospital, Beijing, China; Center for Cardiovascular Translational Research, Peking University People's Hospital, Beijing, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Cardiology, Peking University People's Hospital, Beijing, China; Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People's Hospital, Beijing, China; Center for Cardiovascular Translational Research, Peking University People's Hospital, Beijing, China.
authors.forename: Jun-Xian
authors.initials: JX
authors.lastname: Song
keywords: Acute myocardial infarction; Age; Diabetes mellitus; In-hospital prognosis; Reperfusion therapy