title: Recovery After Critical Illness Polyneuropathy in a Patient With Orthotopic Liver Transplantation: A Case Report.
abstract: After liver transplantation, some patients show neuromuscular abnormalities. A 43-year-old man with liver cirrhosis due to hepatitis C virus underwent living-donor liver transplantation. He developed severe neuromuscular dysfunction after sepsis, and acute respiratory distress syndrome. After the inflammatory reaction gradually improved, we observed bilateral weakness of the extremities and foot drop. Electrophysiological studies indicated primary axonal degeneration of peripheral motor and sensory fibers without inflammation. Critical illness polyneuropathy was diagnosed. During follow-up, complaints gradually recovered with rehabilitation by approximately 1 year later. Based on this case, we suggest that paralysis should be evaluated for critical illness polyneuropathy in patients with unexplained muscle weakness.
authors.affiliation: Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Ehime University Graduate School of Medicine, Toon Ehime, Japan. Electronic address: watanajo@m.ehime-u.ac.jp.
authors.forename: J
authors.initials: J
authors.lastname: Watanabe
authors.affiliation: Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Ehime University Graduate School of Medicine, Toon Ehime, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Ito
authors.affiliation: Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Ehime University Graduate School of Medicine, Toon Ehime, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hatano
authors.affiliation: Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Ehime University Graduate School of Medicine, Toon Ehime, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tohyama
authors.affiliation: Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon Ehime, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Okada
authors.affiliation: Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Ehime University Graduate School of Medicine, Toon Ehime, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Takada
mesh_terms: D000328:Adult; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D011115:Polyneuropathies / Q000209:etiology*; D012128:Respiratory Distress Syndrome / Q000209:etiology