title: Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway.
abstract: Dementia is associated with a worse prognosis of hip fracture, but the impact of a dedicated geriatric care pathway on the prognosis of these patients has not been evaluated.
  
  
  
  According to the cognitive status before surgery, our main objective was to compare mortality rate at 6 months; secondary outcomes were to compare in-hospital complications, the risk of new institutionalization, and the ability to walk at 6 months.
  
  
  
  Between 2009 and 2015, all patients (>70 years) admitted after hip fracture surgery into a dedicated unit of peri-operative geriatric care were included: patients with dementia (DP), without dementia (NDP), and with cognitive status not determined (CSND). Data are expressed as hazard ratio (HR) for multivariate cox analysis or odds ratio (OR) for multivariate logistic regression analysis and their 95% confidence interval (CI).
  
  
  
  We included 650 patients (86±6 years): 168 DP, 400 NDP, and 82 CSND. After adjustment for age, sex, comorbidities, polypharmacy, pre-fracture autonomy, time-to-surgery, and delirium, there were no significant differences for 6-month mortality (DP versus NDP: HR = 0.7[0.4-1.2], DP versus CSND: HR = 0.6[0.3-1.4], CSND versus NDP: HR = 0.8[0.4-1.7]); but DP and CSND were more likely to be newly institutionalized after 6 months compared to NDP (OR DP = 2.6[1.4-4.9], p = 0.003, OR CSND = 2.9[1.4-6.1], p = 0.004). 92% of population was walking after 6 months (63% with assistance): no difference was found between the three groups.
  
  
  
  In a dedicated geriatric care pathway, DP and CSND undergoing hip surgery have the same 6-month mortality and walking ability as NDP.
authors.affiliation: Department of Geriatrics, Unit of Peri-Operative Geriatric Care, Groupe Hospitalier (GH) Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.|Sorbonne University, University Pierre and Marie Curie (UPMC) Paris 06, University Hospital Department Fight Aging and Stress (DHU FAST), Paris, France.
authors.forename: Lorene
authors.initials: L
authors.lastname: Zerah
authors.affiliation: Department of Geriatrics, Unit of Peri-Operative Geriatric Care, Groupe Hospitalier (GH) Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.
authors.forename: Judith
authors.initials: J
authors.lastname: Cohen-Bittan
authors.affiliation: Sorbonne University, University Pierre and Marie Curie (UPMC) Paris 06, University Hospital Department Fight Aging and Stress (DHU FAST), Paris, France.|Departments of Anesthesiology and Critical Care, GH Pitié-Salpêtrière, APHP, Paris, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Raux
authors.affiliation: Department of Rehabilitation, GH Charles Foix, APHP, Ivry sur Seine, France.
authors.forename: Anthony
authors.initials: A
authors.lastname: Meziere
authors.affiliation: Sorbonne University, University Pierre and Marie Curie (UPMC) Paris 06, University Hospital Department Fight Aging and Stress (DHU FAST), Paris, France.|Centre National de la Recherche Scientifique (CNRS), UMR 8256, Paris, France.
authors.forename: Cendrine
authors.initials: C
authors.lastname: Tourette
authors.affiliation: Sorbonne University, University Pierre and Marie Curie (UPMC) Paris 06, University Hospital Department Fight Aging and Stress (DHU FAST), Paris, France.|Centre National de la Recherche Scientifique (CNRS), UMR 8256, Paris, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Neri
authors.affiliation: Department of Geriatrics, Unit of Peri-Operative Geriatric Care, Groupe Hospitalier (GH) Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.|Sorbonne University, University Pierre and Marie Curie (UPMC) Paris 06, University Hospital Department Fight Aging and Stress (DHU FAST), Paris, France.|Centre National de la Recherche Scientifique (CNRS), UMR 8256, Paris, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Verny
authors.affiliation: Sorbonne University, University Pierre and Marie Curie (UPMC) Paris 06, University Hospital Department Fight Aging and Stress (DHU FAST), Paris, France.|Departments of Emergency Medicine and Surgery, GH Pitié-Salpêtrière, APHP, Paris, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Riou
authors.affiliation: Departments of Orthopedic Surgery and Trauma, GH Pitié-Salpêtrière, APHP, Paris, France.
authors.forename: Frederic
authors.initials: F
authors.lastname: Khiami
authors.affiliation: Department of Geriatrics, Unit of Peri-Operative Geriatric Care, Groupe Hospitalier (GH) Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.|Sorbonne University, University Pierre and Marie Curie (UPMC) Paris 06, University Hospital Department Fight Aging and Stress (DHU FAST), Paris, France.|Centre National de la Recherche Scientifique (CNRS), UMR 8256, Paris, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Boddaert
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018376:Cardiovascular Abnormalities / Q000453:epidemiology; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D005853:Geriatrics; D006620:Hip Fractures / Q000150:complications* / Q000453:epidemiology / Q000401:mortality / Q000601:surgery; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D016015:Logistic Models; D008297:Male; D009483:Neuropsychological Tests; D056948:Orthognathic Surgical Procedures / Q000379:methods*; D011446:Prospective Studies; D012189:Retrospective Studies; D013997:Time Factors; D016138:Walking / Q000502:physiology
keywords: Dementia; elderly; hip fracture; unit of peri-operative geriatric care