title: Asthma and other allergic diseases among Saudi schoolchildren in Najran: the need for a comprehensive intervention program.
abstract: BACKGROUND
  In the last three decades, an increasing incidence of allergic diseases has been associated with increasing morbidity and mortality in children and young adults.
  
  
  OBJECTIVE
  The study aimed to investigate the prevalence and risk factors associated with allergic diseases among Saudi schoolchildren in the southwestern Saudi region of Najran, and to determine the sensitization of patients to a set of allergens.
  
  
  METHODS
  Cross-sectional observational study.
  
  
  METHODS
  Primary, intermediate and secondary schools, Najran, Saudi Arabia.
  
  
  METHODS
  All participants completed the Arabic version of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Skin prick tests (SPT) were performed, using a panel of standardized allergenic extracts.
  
  
  METHODS
  Prevalence and risk factors associated with pediatric allergic diseases.
  
  
  RESULTS
  The study included 1700 Saudi schoolchildren. The overall prevalence of physician-diagnosed asthma, allergic rhinitis and atopic dermatitis was 27.5%, 6.3% and 12.5%, respectively. Multivariate analysis showed that male gender (adjusted odds ratio [aOR], 1.27), fast food consumption (aOR, 1.53), trucks passing near houses (aOR, 1.86), and having a dog or cat at home (aOR, 1.85) were significant risk factors. A total of 722 (42.5%) children had a positive SPT result to at least one allergen. The most prevalent allergens were grass pollens (60%), cat fur (41.6%), and house dust mites (25%).
  
  
  CONCLUSIONS
  The findings of this study highlight the urgent need for developing an effective interven- tion program including several components working in harmony to control and reduce the burden of allergic diseases.
  
  
  CONCLUSIONS
  These results may not be generalizable to the rest of Saudi Arabia.
authors.affiliation: Prof. Jobran Miree Alqahtani, Department of Pediatrics,, Najran University,, Najran 61411,, Saudi Arabia, T: +9665428000,, F: +9665428333, jobranm@hotmail.com, ORCID: http://orcid.org/0000-0003-3198-7576.
authors.forename: Jobran M
authors.initials: JM
authors.lastname: Alqahtani
mesh_terms: D000293:Adolescent; D000397:Air Pollution / Q000009:adverse effects; D000485:Allergens / Q000009:adverse effects; D000818:Animals; D001249:Asthma / Q000453:epidemiology* / Q000209:etiology; D002415:Cats; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000453:epidemiology* / Q000209:etiology; D004285:Dogs; D057140:Fast Foods; D005260:Female; D006197:Hair; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D057805:Pets; D011058:Pollen; D015995:Prevalence; D039981:Pyroglyphidae; D065631:Rhinitis, Allergic / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D012529:Saudi Arabia / Q000453:epidemiology; D012737:Sex Factors; D012882:Skin Tests; D011795:Surveys and Questionnaires
chemical_list: D000485:Allergens