title: [Using a high inspiratory oxygen fraction during surgery].
abstract: In this article we discuss the current level of evidence for using a high inspiratory oxygen fraction (0.60-0.90) during surgery. More than 7,000 patients have been included in randomized trials, but no significant beneficial effect was found in a recent meta-analysis as compared with 0.30-0.40 oxygen. A high oxygen fraction should be used to correct or prevent hypoxaemia in special situations, but the available studies do not allow a recommendation to use a high inspiratory oxygen fraction as a routine practice in surgical patients.
authors.affiliation: lars.simon.rasmussen.01@regionh.dk.
authors.forename: Trine Grodum
authors.initials: TG
authors.lastname: Eskesen
authors.forename: Jacob
authors.initials: J
authors.lastname: Steinmetz
authors.forename: Lars S
authors.initials: LS
authors.lastname: Rasmussen
mesh_terms: D006801:Humans; D010100:Oxygen / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control; D013514:Surgical Procedures, Operative; D013530:Surgical Wound Infection / Q000517:prevention & control
chemical_list: D010100:Oxygen