title: Risk of HIV Escape using Sub-Optimal Antiretroviral Dual or Monotherapy.
abstract: Budget constrictions have pushed some researchers to explore whether antiretroviral therapy with one or two drugs instead of the well-established triple-drug regimens may be able to maintain undetectable viremia in HIV-infected individuals, at least used as simplification in patients already with viral suppression under standard triple therapy. With the advent of co-formulations and the improved safety of the newest antiretroviral agents, there is no other reason than cost to justify moving from triple to dual or monotherapy.
authors.affiliation: Department of Internal Medicine, Puerta de Hierro Research Institute, Majadahonda, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: de Mendoza
mesh_terms: D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology*; D015497:HIV-1 / Q000187:drug effects / Q000502:physiology; D006801:Humans; D012307:Risk Factors; D014779:Virus Replication / Q000187:drug effects
chemical_list: D019380:Anti-HIV Agents