title: Complete genome sequence of Streptococcus troglodytae TKU31 isolated from the oral cavity of a chimpanzee (Pan troglodytes).
abstract: Streptococcus troglodytae TKU31 was isolated from the oral cavity of a chimpanzee (Pan troglodytes) and was found to be the most closely related species of the mutans group streptococci to Streptococcus mutans. The complete sequence of TKU31 genome consists of a single circular chromosome that is 2,097,874 base pairs long and has a G + C content of 37.18%. It possesses 2082 coding sequences (CDSs), 65 tRNAs and five rRNA operons (15 rRNAs). Two clustered regularly interspaced short palindromic repeats, six insertion sequences and two predicted prophage elements were identified. The genome of TKU31 harbors some putative virulence associated genes, including gtfB, gtfC and gtfD genes encoding glucosyltransferase and gbpA, gbpB, gbpC and gbpD genes encoding glucan-binding cell wall-anchored protein. The deduced amino acid identity of the rhamnose-glucose polysaccharide F gene (rgpF), which is one of the serotype determinants, is 91% identical with that of S. mutans LJ23 (serotype k) strain. However, two other virulence-associated genes cnm and cbm, which encode the collagen-binding proteins, were not found in the TKU31 genome. The complete genome sequence of S. troglodytae TKU31 has been deposited at DDBJ/European Nucleotide Archive/GenBank under the accession no. AP014612.
authors.affiliation: Department of Translational Research, Tsurumi University School of Dental Medicine.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Okamoto
authors.affiliation: Division of Microbiology and Oral Infection, Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588.
authors.forename: Mariko
authors.initials: M
authors.lastname: Naito
authors.affiliation: Department of Translational Research, Tsurumi University School of Dental Medicine.
authors.forename: Mayu
authors.initials: M
authors.lastname: Miyanohara
authors.affiliation: Department of Translational Research, Tsurumi University School of Dental Medicine.
authors.forename: Susumu
authors.initials: S
authors.lastname: Imai
authors.affiliation: Department of Translational Research, Tsurumi University School of Dental Medicine.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Nomura
authors.affiliation: Department of Operative Dentistry, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama 230-8501.
authors.forename: Wataru
authors.initials: W
authors.lastname: Saito
authors.affiliation: Department of Operative Dentistry, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama 230-8501.
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Momoi
authors.affiliation: Department of Oral Microbiology, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, 271-8587.
authors.forename: Kazuko
authors.initials: K
authors.lastname: Takada
authors.affiliation: Center for Human Evolution Modeling Research and.
authors.forename: Takako
authors.initials: T
authors.lastname: Miyabe-Nishiwaki
authors.affiliation: Language and Intelligence Section, Primate Research Institute, Kyoto University, Inuyama, Aichi 484-8506, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Tomonaga
authors.affiliation: Department of Translational Research, Tsurumi University School of Dental Medicine.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Hanada
mesh_terms: D000818:Animals; D001482:Base Composition; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D020071:Interspersed Repetitive Sequences; D009055:Mouth / Q000382:microbiology*; D002679:Pan troglodytes / Q000382:microbiology*; D012091:Repetitive Sequences, Nucleic Acid; D017422:Sequence Analysis, DNA; D013291:Streptococcus / Q000235:genetics* / Q000302:isolation & purification; D037521:Virulence Factors / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D037521:Virulence Factors
keywords: Streptococcus troglodytae; mutans streptococci; whole genome sequence