title: Incidence of Diabetes Mellitus After Kidney Transplantation in Slovakia: Multicentric, Prospective Analysis.
abstract: The incidence rate of post-transplant diabetes mellitus (PTDM) after kidney transplantation (KT) is 5% to 40%. The objective of this analysis was to identify the risk factors of PTDM after KT in the Slovak Republic (SR).
  
  
  
  In the group of 133 patients/non-diabetics, we identified the risk factors of PTDM in the monitored period of 12 months from transplantation.
  
  
  
  The incidence of PTDM in the SR in 2014 was 38.3%. By logistic regression, we discovered that the age at the time of KT [odds ratio, 1.0885; 95% CI, 1.0222-1.1592; P = .0082], the value of body mass index (BMI) at the time of KT [odds ratio, 1.4606; 95% CI, 1.0099-2.1125; P = .0442], and the value of insulin resistance index (homeostatic model assessment for insulin resistance) at the time of KT [odds ratio, 2.5183; 95% CI, 1.7119-3.4692; P < .0001] represented predictive factors of PTDM. The independent risk factors of PTDM in our group were age at the time of KT of more than 60 years [HR 0.3871; 95% CI 0.1659-1.7767; P = .0281], waist circumference at the time of KT in men more than 94 cm and in women more than 80 cm [HR, 3.4833; 95% CI, 1.2789-9.4878 (P = .0146)], BMI at the time of KT [HR 3.0011; 95% CI 1.0725-8.3977 (P = .0363)], and triacylglycerols at the time of KT more than 1.7 mmol/L [HR, 2.9763; 95% CI, 1.0141-8.7352; P = .0471].
  
  
  
  In the group of Slovak patients after kidney transplantation, the dominating risk factor for PTDM development was insulin resistance prior to KT.
authors.affiliation: Surgery Clinic and Transplantation Center, University Hospital in Martin and Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
authors.forename: I
authors.initials: I
authors.lastname: Dedinská
authors.affiliation: Transplant Department, L. Pasteur's University Hospital, Košice, Slovak Republic.
authors.forename: T
authors.initials: T
authors.lastname: Baltesová
authors.affiliation: Transplant Department, L. Pasteur's University Hospital, Košice, Slovak Republic.
authors.forename: Ĺ
authors.initials: Ĺ
authors.lastname: Beňa
authors.affiliation: Department of Transplant Nephrology, II. Internal Clinic of Slovak Medical University, F.D. Roosevelt's Faculty Hospital, Banská Bystrica, Slovak Republic.
authors.forename: M
authors.initials: M
authors.lastname: Čellár
authors.affiliation: I. Internal Clinic, University Hospital Martin and Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
authors.forename: P
authors.initials: P
authors.lastname: Galajda
authors.affiliation: Department of Urology and Renal Transplantation Center, University Hospital Bratislava and Medical Faculty of the Comenius University, Bratislava, Slovak Republic.
authors.forename: M
authors.initials: M
authors.lastname: Chrastina
authors.affiliation: Transplant Department, L. Pasteur's University Hospital, Košice, Slovak Republic.
authors.forename: A
authors.initials: A
authors.lastname: Jurčina
authors.affiliation: Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
authors.forename: L
authors.initials: L
authors.lastname: Kováčiková
authors.affiliation: Surgery Clinic and Transplantation Center, University Hospital in Martin and Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
authors.forename: Ľ
authors.initials: Ľ
authors.lastname: Laca
authors.affiliation: Transplant Department, L. Pasteur's University Hospital, Košice, Slovak Republic.
authors.forename: E
authors.initials: E
authors.lastname: Lacková
authors.affiliation: Surgery Clinic and Transplantation Center, University Hospital in Martin and Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
authors.forename: S
authors.initials: S
authors.lastname: Lauková Valachová
authors.affiliation: Surgery Clinic and Transplantation Center, University Hospital in Martin and Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic. Electronic address: juraj.miklusica@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Miklušica
authors.affiliation: Transplant Department, L. Pasteur's University Hospital, Košice, Slovak Republic.
authors.forename: J
authors.initials: J
authors.lastname: Rosenberger
authors.affiliation: Department of Urology and Renal Transplantation Center, University Hospital Bratislava and Medical Faculty of the Comenius University, Bratislava, Slovak Republic.
authors.forename: M
authors.initials: M
authors.lastname: Sersenová
authors.affiliation: Surgery Clinic and Transplantation Center, University Hospital in Martin and Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
authors.forename: P
authors.initials: P
authors.lastname: Skalová
authors.affiliation: Department of Urology and Renal Transplantation Center, University Hospital Bratislava and Medical Faculty of the Comenius University, Bratislava, Slovak Republic.
authors.forename: Z
authors.initials: Z
authors.lastname: Žilinská
authors.affiliation: I. Internal Clinic, University Hospital Martin and Jessenius Medical Faculty of the Comenius University, Martin, Slovak Republic.
authors.forename: M
authors.initials: M
authors.lastname: Mokáň
mesh_terms: D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007333:Insulin Resistance; D016030:Kidney Transplantation / Q000009:adverse effects; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D012307:Risk Factors; D018154:Slovakia