title: Imaging in the diagnosis and management of peripheral psoriatic arthritis-The clinical utility of magnetic resonance imaging and ultrasonography.
abstract: Psoriatic arthritis (PsA) is an inflammatory joint disease characterised by the presence of arthritis and often enthesitis and/or spondylitis in patients with psoriasis. However, it presents a wide range of disease manifestations in various patterns. Imaging is an important part of management of PsA, and is used for multiple reasons including establishing/confirming a diagnosis of inflammatory joint disease, determining the extent of disease, monitoring activity and damage, assessing therapeutic efficacy, and identifying complications of disease or treatment, in the setting of clinical practice or clinical studies. Magnetic resonance imaging (MRI) allows detailed assessment of all peripheral and axial joints involved in PsA, and can visualise both inflammation and structural changes. Ultrasonography (US) can visualise many of the peripheral heterogeneous tissue compartments affected by PsA. In contrast to MRI, US is not useful for assessing axial involvement in the spine and sacroiliac joints. In this paper, we will provide an overview of the status, strengths and limitations of MRI and US in peripheral PsA in routine clinical practice and clinical trials.
authors.affiliation: Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Nordre Ringvej 57, DK-2600 Glostrup, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: mo@dadlnet.dk.
authors.forename: Mikkel
authors.initials: M
authors.lastname: Østergaard
authors.affiliation: Women's College Research Institute, Women's College Hospital, 76 Grenville Street, Toronto, Ontario, M5S 1B2, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Lihi
authors.initials: L
authors.lastname: Eder
authors.affiliation: Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Nordre Ringvej 57, DK-2600 Glostrup, Copenhagen, Denmark.
authors.forename: Sara Nysom
authors.initials: SN
authors.lastname: Christiansen
authors.affiliation: Division of Rheumatology, University of Florida College of Medicine, Jacksonville, FL, USA.
authors.forename: Gurjit S
authors.initials: GS
authors.lastname: Kaeley
mesh_terms: D015535:Arthritis, Psoriatic / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*
keywords: Enthesitis; Imaging; Magnetic resonance imaging; Psoriatic arthritis; Synovitis; Ultrasonography