title: Rare Paravertebral and Skull Base Metastases in Prostate Cancer.
abstract: Prostate cancer is the most commonly diagnosed visceral cancer in the United States. A majority of cases exhibit an insidious course and nonaggressive tumor behavior. Prostate cancer can manifest as lesions which remain localized, regionally invading or metastasize to lymph nodes, bones, and lungs. Here, we report a unique case of metastatic prostate cancer to the right upper mediastinum, presenting as a paravertebral mass within 2 years of initial tissue diagnosis. Paravertebral spread has not been described for prostate cancer, and herein, we discuss the clinical presentation, diagnostic workup, and possible therapeutic options available in light of the literature.
authors.affiliation: Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
authors.forename: Gbeminiyi
authors.initials: G
authors.lastname: Samuel
authors.affiliation: Howard University College of Medicine, Washington, DC, USA.
authors.forename: Amir
authors.initials: A
authors.lastname: Isbell
authors.affiliation: Division of Hematology and Oncology, Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
authors.forename: Onyekachi
authors.initials: O
authors.lastname: Ogbonna
authors.affiliation: Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
authors.forename: Hasan
authors.initials: H
authors.lastname: Iftikhar
authors.affiliation: Division of Hematology and Oncology, Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
authors.forename: Susmita
authors.initials: S
authors.lastname: Sakruti
authors.affiliation: Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
authors.forename: Adebayo
authors.initials: A
authors.lastname: Atanda
authors.affiliation: Division of Hematology and Oncology, Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
authors.forename: Raj P
authors.initials: RP
authors.lastname: Manchandani
keywords: Mixed sclerotic and lytic lesions; Paravertebral metastasis; Prostate cancer; Skull base metastasis