title: Intrapancreatic Splenule in a Pancreas Allograft: Case Report.
abstract: A 16-year-old white man was involved in a motor vehicle collision and suffered head, chest, and abdominal trauma. Despite initial resuscitative efforts, he progressed to brain death and was designated to be an organ donor by his family. He had no earlier medical or surgical history and no high-risk behaviors. Blood work revealed normal creatinine, liver function tests, lipase, and amylase. Viral serologies were negative except for cytomegalovirus IgG and Epstein-Barr virus nucleic acid. Imaging revealed a right kidney contusion, a manubrial fracture, and fractures of right first rib and bilateral scapulae. No other abdominal trauma was identified, specifically to the pancreas, duodenum, or spleen. Our transplant center accepted the pancreas from this donor. During back-table inspection of the pancreas, a 1.5 × 1.5 cm dark purple rubbery mass was identified within the parenchyma of the pancreas in the tail. An incisional biopsy of the lesion was sent for frozen section, which yielded a mixed inflammatory infiltrate consisting of neutrophils and lymphocytes and an overlying fibrous capsule. The diagnosis of lymphoma or another neoplasm could not be definitely ruled out. Owing to uncertainty in diagnosis, the entire lesion was excised along with the distal pancreas with the use of a linear stapler. The staple line was oversewn with running 4-0 polypropylene suture, and the pancreas was transplanted. After surgery, the pancreas allograft functioned well with a small pancreatic leak, which had resolved by the first postoperative outpatient visit.
authors.affiliation: Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, Minnesota. Electronic address: drkunalyadav01@gmail.com.
authors.forename: K
authors.initials: K
authors.lastname: Yadav
authors.affiliation: Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, Minnesota.
authors.forename: O K
authors.initials: OK
authors.lastname: Serrano
authors.affiliation: Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, Minnesota.
authors.forename: R
authors.initials: R
authors.lastname: Kandaswamy
mesh_terms: D000293:Adolescent; D064591:Allografts / Q000473:pathology*; D006801:Humans; D008297:Male; D010179:Pancreas / Q000473:pathology*; D016035:Pancreas Transplantation; D014019:Tissue Donors