title: Randomized Controlled Trial of Hepatic Portal Reocclusion as a New Option for Detecting Bile Leakage during Hepatic Resection.
abstract: OBJECTIVE
  To explore the possibility and feasibility of hepatic portal reocclusion for detecting bile leakage during hepatectomy.
  
  
  METHODS
  Data were prospectively collected from 200 patients who underwent hepatectomy alone for removal of various benign or malignant tumors between March 2014 and November 2014. The surgical procedure used a conventional method for all patients, and one additional step (hepatic portal reocclusion) was included in group B. The postoperative outcomes of the patients in group A (subjected to the traditional procedure) and group B (subjected to hepatic portal reocclusion) were compared during the same period, and the incidence rates of postoperative bile leakage and other complications in the 2 groups were also analyzed.
  
  
  RESULTS
  The incidence of postoperative bile leakage in group B was significantly lower than that in group A (1.0 vs. 9.2%, p = 0.009), although no significant differences in postoperative indicators of liver dysfunction and other complications were observed between the 2 groups (p > 0.05).
  
  
  CONCLUSIONS
  Hepatic portal reocclusion effectively reduced the incidence of bile leakage compared to the traditional procedure, without significantly affecting liver function. Therefore, this method might be an alternative to other tests for bile leakage.
authors.affiliation: Department of Hepatic Surgery, The Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Jun-Yong
authors.initials: JY
authors.lastname: Ma
authors.forename: Xi-Feng
authors.initials: XF
authors.lastname: Li
authors.forename: Zhen-Lin
authors.initials: ZL
authors.lastname: Yan
authors.forename: Mohammad Mahboob
authors.initials: MM
authors.lastname: Hasan
authors.forename: Kui
authors.initials: K
authors.lastname: Wang
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.forename: Wen-Chao
authors.initials: WC
authors.lastname: Wang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Yan
authors.forename: Feng
authors.initials: F
authors.lastname: Shen
authors.forename: Le-Hua
authors.initials: LH
authors.lastname: Shi
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D001646:Bile; D001652:Bile Ducts / Q000601:surgery*; D006528:Carcinoma, Hepatocellular / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007431:Intraoperative Complications / Q000175:diagnosis*; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies
keywords: Bile leakage; Hepatectomy; Hepatic portal reocclusion