title: Palmoplantar psoriasis.
abstract: Palmoplantar psoriasis refers to a localized psoriasis variant. The disease can be associated with many clinical forms, including predominantly pustular lesions to thick scaly, hyperkeratotic plaques, or an overlapping of both of them. Palmoplantar psoriasis accounts for 3-4% of all psoriasis cases in most studies. Although it is localized only on the palms and the soles, the fissures, the hardening of the tissue, and hyperkeratosis affect daily routine activities. Taking the body surface area as a measure of severity can sometimes be misleading. In clinical practice, the level of functional impairment should be taken into account rather than relying on traditional instruments to evaluate the severity. Palmoplantar psoriasis is usually managed with topical therapy as a first step. Systemic therapy is needed when the topicals fail or when the disease becomes more severe. Sometimes, biologic agents are required for adequate maintenance of clinical response.
authors.affiliation: Department of Dermatology, Cerrahpaşa Medical Faculty, İstanbul University, Fatih, İstanbul, Turkey. Electronic address: burhanengin2000@yahoo.com.
authors.forename: Burhan
authors.initials: B
authors.lastname: Engin
authors.affiliation: Department of Dermatology, Cerrahpaşa Medical Faculty, İstanbul University, Fatih, İstanbul, Turkey.
authors.forename: Özge
authors.initials: Ö
authors.lastname: Aşkın
authors.affiliation: Department of Dermatology, Cerrahpaşa Medical Faculty, İstanbul University, Fatih, İstanbul, Turkey.
authors.forename: Yalçın
authors.initials: Y
authors.lastname: Tüzün
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001688:Biological Products / Q000627:therapeutic use*; D003033:Coal Tar / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005533:Foot Dermatoses / Q000209:etiology / Q000628:therapy*; D006229:Hand Dermatoses / Q000209:etiology / Q000628:therapy*; D006801:Humans; D009539:Nicotinic Acids / Q000627:therapeutic use; D011701:PUVA Therapy; D011565:Psoriasis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D012176:Retinoids
chemical_list: D000305:Adrenal Cortex Hormones; D001688:Biological Products; D003033:Coal Tar; D003879:Dermatologic Agents; D009539:Nicotinic Acids; C086827:tazarotene; D012176:Retinoids