title: Molecular Imprinting for Substrate Selectivity and Enhanced Activity of Enzyme Mimics.
abstract: Using molecular imprinting, a peroxidase-mimicking DNAzyme has achieved substrate specificity with enhanced activity in a nanoscale gel for three different substrates.
authors.affiliation: Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Ave W, Waterloo, ON, N2L 3G1, Canada.
authors.forename: Zijie
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Ave W, Waterloo, ON, N2L 3G1, Canada.
authors.forename: Biwu
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Ave W, Waterloo, ON, N2L 3G1, Canada.
authors.forename: Juewen
authors.initials: J
authors.lastname: Liu
mesh_terms: D055162:Biocatalysis; D002151:Calorimetry; D021881:DNA, Catalytic / Q000378:metabolism*; D007700:Kinetics; D054802:Molecular Imprinting / Q000379:methods*; D010084:Oxidation-Reduction; D009195:Peroxidase / Q000378:metabolism; D013379:Substrate Specificity; D013696:Temperature
chemical_list: D021881:DNA, Catalytic; D009195:Peroxidase
keywords: DNA; aptamers; enzymes; hydrogels; molecular imprinting