title: Marine Organisms with Anti-Diabetes Properties.
abstract: Diabetes is a chronic degenerative metabolic disease with high morbidity and mortality rates caused by its complications. In recent years, there has been a growing interest in looking for new bioactive compounds to treat this disease, including metabolites of marine origin. Several aquatic organisms have been screened to evaluate their possible anti-diabetes activities, such as bacteria, microalgae, macroalgae, seagrasses, sponges, corals, sea anemones, fish, salmon skin, a shark fusion protein as well as fish and shellfish wastes. Both in vitro and in vivo screenings have been used to test anti-hyperglycemic and anti-diabetic activities of marine organisms. This review summarizes recent discoveries in anti-diabetes properties of several marine organisms as well as marine wastes, existing patents and possible future research directions in this field.
authors.affiliation: Department of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. chiara.lauritano@szn.it.
authors.forename: Chiara
authors.initials: C
authors.lastname: Lauritano
authors.affiliation: Department of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. adrianna.ianora@szn.it.
authors.forename: Adrianna
authors.initials: A
authors.lastname: Ianora
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry; D000959:Antihypertensive Agents / Q000737:chemistry* / Q000494:pharmacology*; D059001:Aquatic Organisms / Q000737:chemistry*; D001419:Bacteria / Q000737:chemistry; D003920:Diabetes Mellitus / Q000188:drug therapy*; D005399:Fishes; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology*; D058086:Microalgae / Q000737:chemistry; D011161:Porifera / Q000737:chemistry; D012624:Seaweed / Q000737:chemistry
chemical_list: D000959:Antihypertensive Agents; D007004:Hypoglycemic Agents
keywords: diabetes; drug discovery; marine biotechnology; marine organisms; metabolic disorder; microalgae