title: Serotypes and Antimicrobial Resistance in Salmonella enterica Recovered from Clinical Samples from Cattle and Swine in Minnesota, 2006 to 2015.
abstract: Salmonellosis remains one of the leading causes of foodborne disease worldwide despite preventive efforts at various stages of the food production chain. The emergence of multi-drug resistant (MDR) non-typhoidal Salmonella enterica represents an additional challenge for public health authorities. Food animals are considered a major reservoir and potential source of foodborne salmonellosis; thus, monitoring of Salmonella strains in livestock may help to detect emergence of new serotypes/MDR phenotypes and to gain a better understanding of Salmonella epidemiology. For this reason, we analyzed trends over a nine-year period in serotypes, and antimicrobial resistance, of Salmonella isolates recovered at the Minnesota Veterinary Diagnostic Laboratory (MVDL) from swine (n = 2,537) and cattle (n = 1,028) samples. Prevalence of predominant serotypes changed over time; in swine, S. Typhimurium and S. Derby decreased and S. Agona and S. 4,5,12:i:- increased throughout the study period. In cattle, S. Dublin, S. Montevideo and S. Cerro increased and S. Muenster became less frequent. Median minimum inhibitory concentration (MIC) values and proportion of antibiotic resistant isolates were higher for those recovered from swine compared with cattle, and were particularly high for certain antibiotic-serotype combinations. The proportion of resistant swine isolates was also higher than observed in the NARMS data, probably due to the different cohort of animals represented in each dataset. Results provide insight into the dynamics of antimicrobial resistant Salmonella in livestock in Minnesota, and can help to monitor emerging trends in antimicrobial resistance.
authors.affiliation: Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Samuel
authors.initials: S
authors.lastname: Hong
authors.affiliation: Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Albert
authors.initials: A
authors.lastname: Rovira
authors.affiliation: Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Peter
authors.initials: P
authors.lastname: Davies
authors.affiliation: Epi-interactive, Wellington, New Zealand.
authors.forename: Christina
authors.initials: C
authors.lastname: Ahlstrom
authors.affiliation: Epi-interactive, Wellington, New Zealand.
authors.forename: Petra
authors.initials: P
authors.lastname: Muellner
authors.affiliation: School of Statistics, University of Minnesota, Minneapolis, United States of America.
authors.forename: Aaron
authors.initials: A
authors.lastname: Rendahl
authors.affiliation: Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Karen
authors.initials: K
authors.lastname: Olsen
authors.affiliation: Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Jeff B
authors.initials: JB
authors.lastname: Bender
authors.affiliation: Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Scott
authors.initials: S
authors.lastname: Wells
authors.affiliation: Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Andres
authors.initials: A
authors.lastname: Perez
authors.affiliation: Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, MN, United States of America.
authors.forename: Julio
authors.identifier: http://orcid.org/0000-0002-8999-9417
authors.initials: J
authors.lastname: Alvarez
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002417:Cattle / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D008826:Microbial Sensitivity Tests; D008910:Minnesota; D019779:Salmonella enterica / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D013552:Swine / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents