title: Dexmedetomidine for sedation in pediatric patients who received more than 20 sessions of radiation therapy: two cases report.
abstract: Dexmedetomidine is a highly selective α2-adrenoceptor agonist that demonstrates anxiolytic and analgesic properties without inducing respiratory compromise, which makes it a suitable agent for procedural sedation and imaging studies. In our current case reports, intravenous dexmedetomidine infusion was used to provide sedation to 2 pediatric patients over more than 20 sessions of radiation therapy. On both occasions, dexmedetomidine provided adequate sedation without respiratory depression. However, the required dosage increased with repeated radiation therapy sessions.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Sun-Key
authors.identifier: 0000-0002-0789-5412
authors.initials: SK
authors.lastname: Kim
authors.affiliation: Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Myung-Hee
authors.initials: MH
authors.lastname: Song
authors.affiliation: Department of Anesthesiology and Pain Medicine, Seoul Medical Center, Seoul, Korea.
authors.forename: Il-Jung
authors.initials: IJ
authors.lastname: Lee
authors.affiliation: Department of Anesthesiology and Pain Medicine, Seoul Medical Center, Seoul, Korea.
authors.forename: Jae-Hyuk
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: In-Cheol
authors.identifier: 0000-0002-7386-5043
authors.initials: IC
authors.lastname: Choi
keywords: Dexmedetomidine; Pediatrics; Radiotherapy