title: A Topical Gel From Flax Seed Oil Compared With Hand Splint in Carpal Tunnel Syndrome: A Randomized Clinical Trial.
abstract: This study compared the therapeutic effect of flax seed oil topical gel and hand splint in the treatment of carpal tunnel syndrome. This study was a randomized clinical trial. Forty-nine patients, 96 hands, with mild to moderate idiopathic carpal tunnel syndrome were divided into 2 groups randomly. One group was treated by topical gel and the other group by hand splint. Intensity of symptoms and function before and after intervention was measured via Boston Carpal Tunnel Questionnaire. After intervention, the ANCOVA showed a significant difference between the symptom and function scores of the 2 groups. In both cases, recovery was higher in the gel group ( P < .001). The topical use of flax seed oil gel is more effective in the improvement of symptoms and function of patients with mild to moderate carpal tunnel syndrome as compared with hand splint, and it can be introduced as an effective treatment.
authors.affiliation: 1 School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Setayesh
authors.affiliation: 2 Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Amir Reza
authors.initials: AR
authors.lastname: Sadeghifar
authors.affiliation: 2 Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Nozar
authors.initials: N
authors.lastname: Nakhaee
authors.affiliation: 3 School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Kamalinejad
authors.affiliation: 1 School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Rezaeizadeh
mesh_terms: D000287:Administration, Topical; D000328:Adult; D002349:Carpal Tunnel Syndrome / Q000628:therapy*; D005260:Female; D005782:Gels; D006801:Humans; D008043:Linseed Oil / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D013165:Splints
chemical_list: D005782:Gels; D008043:Linseed Oil
keywords: Persian medicine; carpal tunnel syndrome; flax seed oil