title: Clinical Outcome of Reconstruction Using Frozen Autograft for a Humeral Bone Tumor.
abstract: We developed a frozen autograft technique in which a tumor-bearing bone was treated with liquid nitrogen for reconstruction. The purpose of this study was to evaluate the functional outcomes of this technique after resection of humeral bone tumors.
  
  
  
  Eight patients were included in the study. The freezing range was classified into 2 groups, depending on whether the joint surface of the humeral head was frozen.
  
  
  
  In the joint freezing group, the mean active shoulder abduction and flexion were 43.8° and 55.0°, and the mean International Society of Limb Salvage (ISOLS) score was 70.8%. In the joint preservation group, the mean active shoulder abduction and flexion were 130° and 132°, and the mean ISOLS score was 90.8%. Progressive and massive bone absorption was seen in 3 cases.
  
  
  
  Reconstruction using frozen autograft after resection of humeral bone tumor is our preferred option, especially in shoulder joint preservation surgery.
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kimura
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Yamamoto
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Shirai
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Hideji
authors.initials: H
authors.lastname: Nishida
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Hayashi
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Tanzawa
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Takeuchi
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Miwa
authors.affiliation: Department of Orthopedic Surgery, Kanazawa University, Kanazawa, Japan tsuchi@med.kanazawa-u.ac.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tsuchiya
mesh_terms: D064592:Autografts; D001859:Bone Neoplasms / Q000473:pathology / Q000601:surgery*; D005615:Freezing; D006801:Humans; D006811:Humerus / Q000473:pathology*
keywords: Humeral bone tumor; biological reconstruction; frozen autograft