title: Phytochemical investigations on Artemisia alba Turra growing in the North-East of Italy.
abstract: Artemisia alba Turra (Asteraceae) is an Euro-Mediterranean plant used in Veneto (North-East of Italy) as traditional medicine for the treatment of various diseases. A. alba is a taxonomically problematic species, characterised by common polymorphism leading to a quite high variability in secondary metabolites content. Nonetheless, the phytochemical knowledge on its phytoconstituents, especially non-volatile components, is limited. In the present paper, the phytochemical composition of a tincture obtained from the aerial parts of A. alba growing in Veneto is presented. Extensive chromatographic separations led to the isolation of three new sesquiterpene derivatives, whose structures were elucidated by 1D and 2D NMR experiments and mass spectrometry. Furthermore, flavonoid composition and volatile constituents of the tincture of A. alba were preliminary studied by HPLC-MSnand GC-MS, respectively.
authors.affiliation: a Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.
authors.forename: Gregorio
authors.initials: G
authors.lastname: Peron
authors.affiliation: a Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Baldan
authors.affiliation: a Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Sut
authors.affiliation: a Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Faggian
authors.affiliation: b Orto Botanico del Monte Baldo "V. Pellegrini". Comune di Ferrara di Monte Baldo , Verona , Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Roccabruna
authors.affiliation: b Orto Botanico del Monte Baldo "V. Pellegrini". Comune di Ferrara di Monte Baldo , Verona , Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Zanini
authors.affiliation: a Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Manzini
authors.affiliation: c School of Pharmacy , University of Camerino , Camerino , Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Maggi
authors.affiliation: a Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Dall'Acqua
mesh_terms: D019306:Artemisia / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000032:analysis / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D007558:Italy; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D008519:Medicine, Traditional; D015394:Molecular Structure; D064209:Phytochemicals / Q000032:analysis* / Q000737:chemistry*; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification; D055549:Volatile Organic Compounds / Q000032:analysis / Q000737:chemistry
chemical_list: D005419:Flavonoids; D064209:Phytochemicals; D010936:Plant Extracts; D012717:Sesquiterpenes; D055549:Volatile Organic Compounds
keywords: GC–MS; HPLC–MS; NMR; Sesquiterpene derivatives; flavonoids; volatile constituents