title: Hot Topics in Perioperative Antibiotics for Cataract Surgery.
abstract: Acute-onset postoperative endophthalmitis is an uncommon but potentially serious complication of cataract surgery. Since there are relatively few randomized clinical trials comparing the timing and administration of prophylactic antibiotics, there are wide variations in prevention practices around the world.
  
  
  
  Literature review.
  
  
  
  Antibiotics may be used before surgery, during surgery, or after surgery in an attempt to decrease the rates of endophthalmitis. Antibiotics may be delivered by various routes, including topical, subconjunctival, in the irrigating solution, or by bolus intracameral injection. Polymerase chain reaction and other DNA identification techniques for bacterial isolates and their antibiotic sensitivity profiles will play an important role in future management strategies.
  
  
  
  There is no consensus regarding the precise use of antibiotics in the perioperative period. Because of increased multidrug-resistant bacteria, evolving strategies are needed to address these issues.
authors.affiliation: The Voivodal Specialistic Hospital in Olsztyn, Olsztyn. Poland.
authors.forename: Patrycja
authors.initials: P
authors.lastname: Kuklo
authors.affiliation: Department of Ophthalmology, Poznan City Hospital, ul. Szwajcarska 3, 61-285 Poznan. Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Grzybowski
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 Northwest 17th Street, Miami, FL, 33136. United States.
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Schwartz
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 Northwest 17th Street, Miami, FL, 33136. United States.
authors.forename: Harry W
authors.initials: HW
authors.lastname: Flynn
authors.affiliation: LV Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam. India.
authors.forename: Avinash
authors.initials: A
authors.lastname: Pathengay
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002387:Cataract Extraction / Q000009:adverse effects*; D009877:Endophthalmitis / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D011183:Postoperative Complications / Q000188:drug therapy* / Q000601:surgery
chemical_list: D000900:Anti-Bacterial Agents
keywords: Cefuroxime; Endophthalmitis; Endophthalmitis Vitrectomy Study (EVS); Intracameral antibiotics; Polymerase chain reaction