title: Green synthesis of gold and silver nanoparticles using aqueous extract of Cibotium barometz root.
abstract: Green synthesis of gold (CB-AuNps) and silver (CB-AgNps) nanoparticles using Cibotium barometz root extract was highlighted. CB-AuNps were synthesized almost instantly and CB-AgNps were formed after 25 min in a heated aqueous extract. The formation of CB-AuNps and CB-AgNps was detected at 548 and 412 nm; they were spherical with crystallite sizes of 6 nm and 23 nm, respectively. CB-AgNps were further investigated for their antimicrobial activity against Escherichia, Staphylococcus aureus, Salmonella enterica, and Pseudomonas aeruginosa. Furthermore, scavenging activity against 1,1-diphenyl-2-picrylhydrzyl (DPPH) free radicals was demonstrated. Lastly, the cytotoxic properties of CB-AuNps and CB-AgNps were explored in murine macrophages (RAW264.7) cells and MCF-7 breast cancer cells. This study demonstrated the prospective biomedical applications of CB-AuNps and CB-AgNps as antioxidant, antimicrobial agents, and drug-delivery agents.
authors.affiliation: a Department of Oriental Medicine Biotechnology and Ginseng Bank, College of Life Science , Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Dandan
authors.initials: D
authors.lastname: Wang
authors.affiliation: b Department of Biotechnology , College of Life Science, Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Josua
authors.initials: J
authors.lastname: Markus
authors.affiliation: a Department of Oriental Medicine Biotechnology and Ginseng Bank, College of Life Science , Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.affiliation: a Department of Oriental Medicine Biotechnology and Ginseng Bank, College of Life Science , Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Yeon-Ju
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: b Department of Biotechnology , College of Life Science, Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Ramya
authors.initials: R
authors.lastname: Mathiyalagan
authors.affiliation: a Department of Oriental Medicine Biotechnology and Ginseng Bank, College of Life Science , Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Verónica Castro
authors.initials: VC
authors.lastname: Aceituno
authors.affiliation: a Department of Oriental Medicine Biotechnology and Ginseng Bank, College of Life Science , Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Sungeun
authors.initials: S
authors.lastname: Ahn
authors.affiliation: a Department of Oriental Medicine Biotechnology and Ginseng Bank, College of Life Science , Kyung Hee University , Yongin , Republic of Korea.|b Department of Biotechnology , College of Life Science, Kyung Hee University , Yongin , Republic of Korea.
authors.forename: Deok Chun
authors.initials: DC
authors.lastname: Yang
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects; D060326:Chemistry Techniques, Synthetic; D006046:Gold / Q000737:chemistry*; D055772:Green Chemistry Technology; D006801:Humans; D061986:MCF-7 Cells; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry*; D000067996:RAW 264.7 Cells; D012834:Silver / Q000737:chemistry*; D064028:Tracheophyta / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D014867:Water; D012834:Silver; D006046:Gold
keywords: Cibotium barometz; Green synthesis; antimicrobial effect; antioxidant activity; cytotoxicity; nanoparticles