title: Synthesis of 6-Substituted 6H-Indolo[2,3-b]quinolines from Isoindigos.
abstract: A facile approach to 6-aryl/alkyl substituted 6H-indolo[2,3-b]quinolines from mono-N-substituted isoindigo derivatives in the presence of SnCl2·2H2O in acid media is described. Pyrrole and pyridine rings are synchronously constructed in one pot for these tetracyclic molecules. A plausible reduction/hydrolysis/decarboxylation/cyclization/aromatization domino reaction mechanism is proposed. Bis-N-substituted isoindigo only gives the corresponding reduction product, 3,3'-bioxindole.
authors.affiliation: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors.forename: Ling
authors.initials: L
authors.lastname: Fan
authors.affiliation: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors.forename: Meilin
authors.initials: M
authors.lastname: Liu
authors.affiliation: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Ye
authors.affiliation: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors.forename: Guodong
authors.identifier: 0000-0002-8095-0625
authors.initials: G
authors.lastname: Yin