title: Challenges in the management of chronic pulmonary aspergillosis.
abstract: The management of chronic pulmonary aspergillosis (CPA) presents multiple challenges. We present three cases that illustrate some of the most challenging aspects of caring for patients with CPA: specifically, antifungal drug resistance, drug interactions, coinfection with nontuberculous mycobacteria, and large-volume hemoptysis.
authors.affiliation: University Hospital of South Manchester NHS Foundation Trust, Manchester Academic Health Science Centre chris.kosmidis@uhsm.nhs.uk.
authors.forename: Chris
authors.initials: C
authors.lastname: Kosmidis
authors.affiliation: University Hospital of South Manchester NHS Foundation Trust, Manchester Academic Health Science Centre.
authors.forename: Eavan G
authors.initials: EG
authors.lastname: Muldoon
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002908:Chronic Disease; D019468:Disease Management; D004347:Drug Interactions; D025141:Drug Resistance, Fungal; D006801:Humans; D009164:Mycobacterium Infections / Q000150:complications; D055732:Pulmonary Aspergillosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents
keywords: case series; chronic pulmonary aspergillosis; haemoptysis; non-tuberculous mycobacteria; resistance