title: Short Route to Cassane-Type Diterpenoids: Synthesis of the Supposed Structure of Benthaminin 1.
abstract: A short route toward aromatic cassane diterpenes from labdane terpenoids has been developed. In the key step, the aromatic ring with the oxygenated function at C-12 and the characteristic carbon group at C-14 of the target compounds is elaborated via a Diels-Alder/aromatization sequence of a furanosesquiterpene and methyl propiolate. On this basis, the synthesis of the proposed structure of benthaminin 1 from trans-communic acid has been achieved. The physical properties of the synthetic compound are somewhat different from those reported for the natural product.
authors.affiliation: Laboratory Productions, Plant and Microbial Valuations (LP2VM), Department of Biotechnology, University of Sciences and Technology of Oran Mohamed Boudiaf , BP 1525, EL M'Naouer, Oran, Algeria.
authors.forename: Soumicha
authors.initials: S
authors.lastname: Mahdjour
authors.affiliation: Laboratory Productions, Plant and Microbial Valuations (LP2VM), Department of Biotechnology, University of Sciences and Technology of Oran Mohamed Boudiaf , BP 1525, EL M'Naouer, Oran, Algeria.
authors.forename: Meriem
authors.initials: M
authors.lastname: Harche-Kaid
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada , 18071 Granada, Spain.
authors.forename: Alí
authors.initials: A
authors.lastname: Haidour
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada , 18071 Granada, Spain.
authors.forename: Rachid
authors.initials: R
authors.lastname: Chahboun
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada , 18071 Granada, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Alvarez-Manzaneda