title: Cognition as a treatment target in depression.
abstract: Cognitive dysfunction in depression is associated with poorer clinical outcomes and impaired psychosocial functioning. However, most treatments for depression do not specifically target cognition. Neurocognitive deficits such as memory and concentration problems tend to persist after mood symptoms recover. Improving cognition in depression requires a better understanding of brain systems implicated in depression. A comprehensive approach is warranted for refined methods of assessing and treating cognitive dysfunction in depression.
authors.affiliation: Department of Psychiatry, University of Cambridge, Cambridge,UK.
authors.forename: M
authors.initials: M
authors.lastname: Kaser
authors.affiliation: Department of Psychiatry, University of Cambridge, Cambridge,UK.
authors.forename: R
authors.initials: R
authors.lastname: Zaman
authors.affiliation: Department of Psychiatry, University of Cambridge, Cambridge,UK.
authors.forename: B J
authors.initials: BJ
authors.lastname: Sahakian
mesh_terms: D060825:Cognitive Dysfunction / Q000209:etiology / Q000628:therapy*; D003866:Depressive Disorder / Q000150:complications / Q000628:therapy*; D006801:Humans
keywords: Cognition; depression; neuropsychological model; treatment target