title: Regioselective Hydrohydroxyalkylation of Styrene with Primary Alcohols or Aldehydes via Ruthenium-Catalyzed C-C Bond Forming Transfer Hydrogenation.
abstract: Transfer hydrogenative coupling of styrene with primary alcohols using the precatalyst HClRu(CO)(PCy3)2modified by AgOTf or HBF4delivers branched or linear adducts from benzylic or aliphatic alcohols, respectively. Related 2-propanol mediated reductive couplings also are described.
authors.affiliation: University of Texas at Austin, Department of Chemistry, 105 E 24th St. A5300, Austin, TX, 78712-1167, USA.
authors.forename: Hongde
authors.initials: H
authors.lastname: Xiao
authors.affiliation: University of Texas at Austin, Department of Chemistry, 105 E 24th St. A5300, Austin, TX, 78712-1167, USA.
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.affiliation: University of Texas at Austin, Department of Chemistry, 105 E 24th St. A5300, Austin, TX, 78712-1167, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Krische
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D000478:Alkylation; D002384:Catalysis; D006865:Hydrogenation; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism; D020058:Styrene / Q000737:chemistry*
chemical_list: D000438:Alcohols; D000447:Aldehydes; D020058:Styrene; D012428:Ruthenium
keywords: C−C bond formation; cross-coupling; homogenous catalysis; hydrogenation; ruthenium