title: [The possibility of using progesterone receptor modulators in the treatment of myomas].
abstract: OBJECTIVE
  To summarize the knowledge about the effect of selective progesterone receptor modulators and their use in the treatment of myomas in women of childbearing age and in perimenopause.
  
  
  METHODS
  Review article.
  
  
  RESULTS
  Long-term treatment with ulipristal acetate maximizes its effectiveness, it helps to achieve faster bleeding control and increases the number of pa-tients with fibroid volume reduction of more than 50%. Ulipristal acetate is the most effective drug in the medical treatment of myomas and its use will change the approach to surgical treatment.
authors.forename: O
authors.initials: O
authors.lastname: Šimetka
authors.forename: J
authors.initials: J
authors.lastname: Klát
authors.forename: S
authors.initials: S
authors.lastname: Bajsová
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000188:drug therapy*; D009649:Norpregnadienes / Q000627:therapeutic use*; D011980:Receptors, Progesterone / Q000819:agonists*; D014594:Uterine Neoplasms / Q000188:drug therapy*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D009649:Norpregnadienes; D011980:Receptors, Progesterone; C555622:ulipristal acetate
keywords: medical therapy; myomas; selective progesteron receptor modulators ulipristal acetate.; surgical therapy