title: Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy.
abstract: Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to comorbid disease-specific therapy, and more toxic treatment can be avoided.
authors.affiliation: Department of Medicine, Division of Gastroenterology, University of California San Francisco, San Francisco, CA.
authors.forename: Jeanne-Marie
authors.initials: JM
authors.lastname: Giard
authors.affiliation: Department of Medicine, Division of Gastroenterology, University of California San Francisco, San Francisco, CA.
authors.forename: Kerry A
authors.initials: KA
authors.lastname: Decker
authors.affiliation: Department of Medicine, Division of Gastroenterology, University of California San Francisco, San Francisco, CA.
authors.forename: Jennifer C
authors.initials: JC
authors.lastname: Lai
authors.affiliation: Department of Pathology, University of California San Francisco, San Francisco, CA.
authors.forename: Ryan M
authors.initials: RM
authors.lastname: Gill
authors.affiliation: Department of Medicine, Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.
authors.forename: Aaron C
authors.initials: AC
authors.lastname: Logan
authors.affiliation: Organ Transplant Department, Swedish Medical Center, Seattle, WA.
authors.forename: Oren K
authors.initials: OK
authors.lastname: Fix