title: Hepatitis C Virus in the Renal Transplant Population: An Update With Focus on the New Era of Antiviral Regimens.
abstract: Chronic hepatitis C virus infection is a global health problem, especially among renal transplant recipients. Herein, we present an overview of hepatitis C virus among renal transplant patients, with a focus on some updated aspects concerning types of viral genotypes, methods of diagnosis, the effects of renal transplant on hepatitis C virus infection, and summary of hepatitis C virus-related complications after renal transplant. We also discuss patient and graft survival rates and the present and future therapeutic options with special focus on new antiviral and possible interactions with immunosuppressive medications.
authors.affiliation: From the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt; and the Hamed Al-Essa Organ Transplant Center, Kuwait.
authors.forename: Osama
authors.initials: O
authors.lastname: Gheith
authors.forename: Medhat A
authors.initials: MA
authors.lastname: Halim
authors.forename: Nashwa
authors.initials: N
authors.lastname: Othman
authors.forename: Torki
authors.initials: T
authors.lastname: Al-Otaibi
authors.forename: Prasad
authors.initials: P
authors.lastname: Nair
authors.forename: Naryanan
authors.initials: N
authors.lastname: Nampoory
mesh_terms: D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D006085:Graft Survival / Q000187:drug effects; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000188:drug therapy* / Q000635:transmission / Q000821:virology; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D007166:Immunosuppressive Agents