title: Molecular and Pharmaceutical Aspects of Novel Methods and Materials for the Prevention of Tooth Structure Loss.
abstract: In the past decade, a range of dental products have appeared which make advertising claims around preventing mineral loss or repairing mineral loss. This review examines the requirements for effective protection of tooth structure, and the evidence around technologies now available for preventing tooth structure loss and repairing demineralized enamel, ranging from tooth surface protection and enhanced fluoride uptake through to calcium compounds, unstabilized amorphous calcium phosphate, tricalcium phosphate, and casein phosphopeptide - amorphous calcium phosphate.
authors.affiliation: School of Dentistry, The University of Queensland, UQ Oral Health Centre, 288 Herston Road, Herston QLD 4006, Brisbane, Australia.
authors.forename: Laurence J
authors.initials: LJ
authors.lastname: Walsh
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology*; D002130:Calcium Phosphates / Q000737:chemistry / Q000494:pharmacology*; D002364:Caseins / Q000737:chemistry / Q000494:pharmacology*; D003743:Dental Enamel / Q000737:chemistry / Q000187:drug effects; D005459:Fluorides / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D012463:Saliva / Q000737:chemistry; D014089:Tooth Remineralization / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D002364:Caseins; C519480:amorphous calcium phosphate; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex; C018392:tricalcium phosphate; D005459:Fluorides
keywords: Remineralization; calcium phosphates; casein phosphopeptides; fluorides; tricalcium phosphate