title: Recurrent Optic Perineuritis after Intranasal Cocaine Abuse.
abstract: Recurrent optic perineuritis can be related to orbital inflammation. Here we present the case of a 46-year-old male patient in whom recurrent episodes of optic perineuritis were related to chronic osteolytic sinusitis following intranasal cocaine abuse. Magnetic resonance imaging (MRI) demonstrated optic perineuritis adjacent to a soft tissue mass that intruded the orbit from the nasal cavity. Computed tomography (CT) confirmed destruction of the medial orbital wall.Staphylococcus aureuswas cultured and biopsy showed granulomatous tissue. Visual outcome was poor. We review the literature and discuss the diagnostic pitfalls and management implications in relation to optic (peri)neuritis originating from the nasal sinuses.
authors.affiliation: VU University Medical Center Amsterdam The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Coppens
authors.affiliation: VU University Medical Center Amsterdam The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Petzold
authors.affiliation: VU University Medical Center Amsterdam The Netherlands.
authors.forename: P
authors.initials: P
authors.lastname: de Graaf
authors.affiliation: VU University Medical Center Amsterdam The Netherlands.
authors.forename: W A E J
authors.initials: WA
authors.lastname: de Vries-Knoppert
keywords: CT; Cocaine; MRI; histology; optic neuritis; optic perineuritis; osteolytic sinusitis