title: Radiofrequency catheter ablation of accessory pathways in patients with Ebstein's anomaly: At 8 years of follow-up.
abstract: BACKGROUND
  Data regarding long-term follow-up of radiofrequency catheter ablation (RFCA) of accessory pathways (APs) in patients with Ebstein's anomaly (EA) are limited. The procedures are challenging due to multiple or wide APs.
  
  
  METHODS
  Analysis was performed on clinical and periprocedural data of patients with EA referred to the centre in order to perform catheter ablation of AP. The group consisted of 22 patients (female 40.9%, mean age 33.6 ± 19.1 years). The follow-up utilized electrocardiogram and Holter monitoring.
  
  
  RESULTS
  Twenty-two patients had 33 accessory pathways (8 patients had multiple APs, 11 patients broad AP). Twenty-nine different arrhythmias were ablated: 20 orthodromic atrioventricular reciprocating tachycardia (O-AVRT), 5 antidromic atrioventricular reciprocating tachycardia (A-AVRT), 3 slow/ fast atrioventricular nodal reentry tachycardia (s/f AVNRT) and 1 cavotricuspid-isthmus-dependent atrial flutter (CTI-AFL). In 3 (13.6%) patients multiple ablation targets for RFCA ablation were observed. The acute procedural success rate after the first RFCA performed was: 100% for AVNRT, 77.3% for APs and 50.0% for CTI-AFL ablation. Follow-up (mean 95.7 ± 49.8 months) was completed in 86.4% of patients. One patient had paroxysmal atrial fibrillation not targeted during ablation. One patient died due to heart failure 12 years after RFCA. Three patients who underwent RFCA of accessory pathways in the mid-1990s were lost in follow-up.
  
  
  CONCLUSIONS
  Radiofrequency ablation in patients with EA is challenging but safe and have a high short-term as well as long-term success rate.
authors.affiliation: National Institute of Cardiology, Arrhythmia Department, Warsaw, Poland. morczykowski@gazeta.pl.
authors.forename: Michał
authors.initials: M
authors.lastname: Orczykowski
authors.forename: Paweł
authors.initials: P
authors.lastname: Derejko
authors.forename: Robert
authors.initials: R
authors.lastname: Bodalski
authors.forename: Piotr
authors.initials: P
authors.lastname: Urbanek
authors.forename: Joanna
authors.initials: J
authors.lastname: Zakrzewska-Koperska
authors.forename: Radosław
authors.initials: R
authors.lastname: Sierpiński
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kalin
authors.forename: Andrzej
authors.initials: A
authors.lastname: Hasiec
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Warmiński
authors.forename: Maria
authors.initials: M
authors.lastname: Miszczak-Knecht
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Bieganowska
authors.forename: Rafał
authors.initials: R
authors.lastname: Baranowski
authors.forename: Maria
authors.initials: M
authors.lastname: Bilińska
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Biernacka
authors.forename: Piotr
authors.initials: P
authors.lastname: Hoffman
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Szumowski
mesh_terms: D058606:Accessory Atrioventricular Bundle / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D017115:Catheter Ablation / Q000379:methods*; D004437:Ebstein Anomaly / Q000150:complications*; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome
keywords: Ebstein’s anomaly; Wolff-Parkinson-White syndrome; accessory pathway; catheter ablation