title: Persistent immune thrombocytopenia heralds the diagnosis ofMycobacterium chimaeraprosthetic valve endocarditis.
abstract: A 63 year old female was admitted for investigation of worsening renal insufficiency. During hospitalization she developed persistent immune thrombocytopenia refractory to supportive or immunosuppressive treatment. She was diagnosed withMycobacterium chimaeraprosthetic valve endocarditis and thrombocytopenia resolved with anti-mycobacterial therapy.
authors.affiliation: Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA.
authors.forename: Keith A
authors.initials: KA
authors.lastname: Sacco
authors.affiliation: Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; Associate Professor, Mayo College of Medicine, Rochester, MN, USA.
authors.forename: M Caroline
authors.initials: MC
authors.lastname: Burton
keywords: ANA, anti-nuclear antibodies; ANCA, anti-neutrophil cytoplasmic antibodies; AVR, aortic valve repair; Aortic root abscess; CT, computerized tomography; ENA, extractable nuclear antigen; Granulomas; HIV, human immunodeficiency virus; ITP, immune thrombocytopenia purpura; IVIG, intravenous immunoglobulin; MRI, magnetic resonance imaging; Mycobacterium chimaera; PVE, prosthetic valve endocarditis; Prosthetic-valve endocarditis; TEE, transesophageal echocardiogram; Thrombocytopenia; eGFR, estimated glomerular filtration rate