title: Bio-Photonic Detection and Quantitative Evaluation Method for the Progression of Dental Caries Using Optical Frequency-Domain Imaging Method.
abstract: The initial detection of dental caries is an essential biomedical requirement to barricade the progression of caries and tooth demineralization. The objective of this study is to introduce an optical frequency-domain imaging technique based quantitative evaluation method to calculate the volume and thickness of enamel residual, and a quantification method was developed to evaluate the total intensity fluctuation in depth direction owing to carious lesions, which can be favorable to identify the progression of dental caries in advance. The cross-sectional images of theex vivotooth samples were acquired using 1.3 μm spectral domain optical coherence tomography system (SD-OCT). Moreover, the advantages of the proposed method over the conventional dental inspection methods were compared to highlight the potential capability of OCT. As a consequence, the threshold parameters obtained through the developed method can be used as an efficient investigating technique for the initial detection of demineralization.
authors.affiliation: School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, Korea. eranga@knu.ac.kr.
authors.forename: Ruchire Eranga
authors.initials: RE
authors.lastname: Wijesinghe
authors.affiliation: Eaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary(MEEI), 243, Charles Street, Boston, MA 02114, USA. namhyun_cho@meei.harvard.edu.|Department of Otology and Laryngology, Harvard Medical School, 243, Charles Street, Boston, MA 02114, USA. namhyun_cho@meei.harvard.edu.
authors.forename: Nam Hyun
authors.initials: NH
authors.lastname: Cho
authors.affiliation: School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, Korea. pepl10@knu.ac.kr.
authors.forename: Kibeom
authors.initials: K
authors.lastname: Park
authors.affiliation: School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, Korea. msjeon@knu.ac.kr.
authors.forename: Mansik
authors.initials: M
authors.lastname: Jeon
authors.affiliation: School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, Korea. jeehk@knu.ac.kr.
authors.forename: Jeehyun
authors.initials: J
authors.lastname: Kim
mesh_terms: D000465:Algorithms; D002648:Child; D003731:Dental Caries / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D003743:Dental Enamel / Q000737:chemistry; D018450:Disease Progression; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D061848:Optical Imaging / Q000379:methods*; D017785:Photons; D041623:Tomography, Optical Coherence / Q000379:methods*; D014070:Tooth / Q000000981:diagnostic imaging / Q000473:pathology; D017001:Tooth Demineralization
keywords: Bio-photonic detection; demineralization; dental caries; optical coherence tomography; optical frequency domain imaging (OFDI)