title: Position of ST-deviation measurements relative to the J-point: Impact for ischemia detection.
abstract: There is no consensus about the time instant relative to the J point where ST deviation has to be measured for detection of acute ischemia in the ECG.
  
  
  
  We analyzed 53 ECGs, recorded preceding emergency catheterization of acute coronary syndrome patients with a completely occluded culprit artery (cases), and 88 control ECGs recorded in the cardiology outpatient clinic. ECG-amplitude measurements were made every 10 ms, between 20 ms before till 80 ms after the J point. STEMI-detection algorithms varied from the traditional STEMI criterion (elevations in at least two adjacent ECG leads), via the STEMI equivalent criterion (depressions in V2 and V3), to the most liberal STEMI-detection algorithm in which elevations as well as depressions in two adjacent leads were considered as signs of ischemia.
  
  
  
  Diagnostic accuracy was highest (93.6%) for the most liberal STEMI-detection algorithm at 10 ms after the J point; sensitivity was 94.3% and specificity was 93.2%.
  
  
  
  The results of our study suggest that STEMI detection close to the J point is optimal.
authors.affiliation: Cardiology Department, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Sumche
authors.initials: S
authors.lastname: Man
authors.affiliation: Cardiology Department, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: C Cato
authors.initials: CC
authors.lastname: Ter Haar
authors.affiliation: Cardiology Department, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Marjolein C
authors.initials: MC
authors.lastname: de Jongh
authors.affiliation: Cardiology Department, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Arie C
authors.initials: AC
authors.lastname: Maan
authors.affiliation: Cardiology Department, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Schalij
authors.affiliation: Cardiology Department, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: c.a.swenne@lumc.nl.
authors.forename: Cees A
authors.initials: CA
authors.lastname: Swenne
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis*; D000328:Adult; D000465:Algorithms; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D000072657:ST Elevation Myocardial Infarction / Q000175:diagnosis*; D012680:Sensitivity and Specificity
keywords: Acute coronary syndrome; Electrocardiography; Myocardial ischemia; ST-deviation measurement; STEMI classification