title: Chromosome Recognition.
abstract: Chromosomal analysis of human cells serves to characterize aberrations of chromosome number and structure. Individual chromosome can be identified precisely by recognition of its morphological characteristics and staining patterns according to specific landmarks, regions, and bands as described in the ideogram. Since the quality of metaphases obtained from malignant cells is generally poor for karyotyping, a practical and accurate chromosome recognition training guide is mandatory for a trainee or newly employed cytogenetic technologist in a cancer cytogenetics laboratory. The most distinguishable bands for each chromosome are described in detail in this chapter with an aim to facilitate quick and accurate karyotyping in cancers. This is an indispensable chromosome recognition guide used in a cancer cytogenetics laboratory.
authors.affiliation: Haematology Division, Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. thomaswan@cuhk.edu.hk.
authors.forename: Thomas S K
authors.initials: TS
authors.lastname: Wan
authors.affiliation: Haematology Division, Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Shatin, Hong Kong.
authors.forename: Eleanor K C
authors.initials: EK
authors.lastname: Hui
authors.affiliation: Haematology Division, Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.
authors.forename: Margaret H L
authors.initials: MH
authors.lastname: Ng
mesh_terms: D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002877:Chromosomes, Human; D020732:Cytogenetic Analysis / Q000379:methods*; D006801:Humans; D059785:Karyotype; D007621:Karyotyping; D008677:Metaphase; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics
keywords: Chromosomal analysis; Chromosome pattern; Chromosome recognition; G-banded karyotyping