title: Ring-Opening Reactions of the N-4-Nosyl Hough-Richardson Aziridine with Nitrogen Nucleophiles.
abstract: Dinosylated α-d-glucopyranoside was directly transformed into α-d-altropyranosides via in situ formed N-4-nosyl Hough-Richardson aziridine with nitrogen nucleophiles under mild conditions in fair to excellent yields. The scope of the aziridine ring-opening reaction was substantially broadened contrary to the conventional methods introducing solely the azide anion at high temperatures. If necessary, the N-4-nosyl Hough-Richardson aziridine can be isolated by filtration in a very good yield and high purity.
authors.affiliation: Institute of Molecular and Translation Medicine, Faculty of Medicine, Palacký University , Hněvotínská 5, 77900 Olomouc, Czech Republic.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Ručil
authors.affiliation: Department of Inorganic Chemistry, Faculty of Science, Palacký University , 17. listopadu 1192/12, 77146 Olomouc, Czech Republic.
authors.forename: Zdeněk
authors.initials: Z
authors.lastname: Trávníček
authors.affiliation: Department of Organic Chemistry, Faculty of Science, Palacký University , 17. listopadu 1192/12, 77146 Olomouc, Czech Republic.
authors.forename: Petr
authors.identifier: 0000-0002-7434-6069
authors.initials: P
authors.lastname: Cankař