title: Ocular Blood Flow Changes in Behçet Disease Patients with/without Thrombotic Disease.
abstract: In this study, the authors aimed to evaluate ocular blood flow changes in Behçet disease (BD) with and without thrombotic disease. Ninety eyes of 90 patients with a diagnosis of BD (30 eyes with active uveitis, 23 eyes with inactive uveitis, 25 eyes without ocular involvement, and 12 eyes without ocular involvement and with a history of thrombosis) and 30 eyes of 30 age- and sex-matched control patients without any systemic disease with a total of 120 eyes were evaluated. In all cases, ophthalmic, central retinal, and ciliary artery flow parameters were measured with colour Doppler ultrasonography (CDU). The ocular blood flow parameters of all vessels in patients with active uveitis were found to be affected. All the flow parameters in the CRAs of the study groups were significantly different from the control group (p< 0.001). Additionally, in non-ocular BD patients with thrombosis, blood flow parameters were affected more than the parameters in non-ocular BD patients without thrombosis and control patients. In conclusion, major haemodynamic changes were observed using CDU in the ophthalmic vessels of ocular Behçet patients. Also, CDU may detect ocular blood flow alterations before initial ocular clinical manifestations appear in BD patients.
authors.affiliation: Department of Ophthalmology.
authors.forename: Harun
authors.initials: H
authors.lastname: Yüksel
authors.affiliation: Department of Ophthalmology.
authors.forename: Fatih M
authors.initials: FM
authors.lastname: Türkcü
authors.affiliation: Department of Radiology, Dicle University Faculty of Medicine Diyarbakir Turkey.
authors.forename: Cihat
authors.initials: C
authors.lastname: Hamidi
authors.affiliation: Department of Ophthalmology.
authors.forename: Abdullah K
authors.initials: AK
authors.lastname: Cingü
authors.affiliation: Department of Ophthalmology.
authors.forename: Yasin
authors.initials: Y
authors.lastname: Çinar
authors.affiliation: Department of Ophthalmology.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Şahin
authors.affiliation: Department of Ophthalmology.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Özkurt
authors.affiliation: Department of Ophthalmology.
authors.forename: İhsan
authors.initials: İ
authors.lastname: Çaça
keywords: Behçet; Doppler; thrombosis; uveitis