title: The class III phosphatidylinositol 3-kinase Vps34 in Saccharomyces cerevisiae.
abstract: The class III phosphatidylinositol 3-kinase Vps34 (vacuolar protein sorting 34) catalyzes for the formation of the signaling lipid phosphatidylinositol-3-phopsphate, which is a central factor in the regulation of autophagy, endocytic trafficking and vesicular transport. In this article, we discuss the functional role of the lipid kinase Vps34 in Saccharomyces cerevisiae.
authors.affiliation: Biochemie Intrazellulärer Transportprozesse, Ruhr-Universität Bochum, D-44801 Bochum.
authors.forename: Christina
authors.initials: C
authors.lastname: Reidick
authors.affiliation: Biochemie Intrazellulärer Transportprozesse, Ruhr-Universität Bochum, D-44801 Bochum.
authors.forename: Fahd
authors.initials: F
authors.lastname: Boutouja
authors.affiliation: Biochemie Intrazellulärer Transportprozesse, Ruhr-Universität Bochum, D-44801 Bochum.
authors.forename: Harald W
authors.initials: HW
authors.lastname: Platta
mesh_terms: D000818:Animals; D058546:Class III Phosphatidylinositol 3-Kinases / Q000737:chemistry / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D021122:Protein Subunits / Q000737:chemistry / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D015398:Signal Transduction
chemical_list: D021122:Protein Subunits; D058546:Class III Phosphatidylinositol 3-Kinases; D019204:GTP-Binding Proteins
keywords: Atg14; G-protein; Vps15; Vps30; Vps34; autophagy; kinase