title: Intraocular Pressure after Intravitreal Triesence Injection.
abstract: OBJECTIVE
  Elevated intraocular pressure (IOP) is a frequent adverse event associated with intravitreal triamcinolone acetate injection. The incidence of elevated IOP with preserved forms of triamcinolone has been studied but the effect of preservative-free formulations has not been clinically evaluated.
  
  
  METHODS
  A retrospective, observational clinical study.
  
  
  METHODS
  For patients undergoing intravitreal injections over the study period, age, sex, history of glaucoma or ocular hypertension were recorded. For each injection, preinjection IOP, maximum IOP (IOPmax), dose, and indication for injection were noted for both eyes.
  
  
  RESULTS
  Fourteen patients received 72 injections in 18 eyes. The mean baseline IOP was 15.4 mm Hg; the mean IOPmaxwas 19.8 mm Hg (P<0.001), occurring 63 days after injection. Outcomes were not significantly different between patients receiving 2 or 4 mg doses. History of glaucoma did not significantly affect IOPmax.
  
  
  CONCLUSIONS
  Eyes should be monitored for IOP rises after preservative-free triamcinolone acetonide injections.
authors.affiliation: a Department of Ophthalmology , Mayo Clinic , Rochester , MN , USA.
authors.forename: Elizabeth A
authors.identifier: http://orcid.org/0000-0002-5640-7630
authors.initials: EA
authors.lastname: Atchison
authors.affiliation: a Department of Ophthalmology , Mayo Clinic , Rochester , MN , USA.
authors.forename: Sophie J
authors.initials: SJ
authors.lastname: Bakri
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D058449:Intravitreal Injections; D008269:Macular Edema / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000139:chemically induced*; D012189:Retrospective Studies; D012307:Risk Factors; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000893:Anti-Inflammatory Agents; D014222:Triamcinolone Acetonide
keywords: Eye; intraocular; pressure; retina; steroid; triamcinolone