title: Case of Orbital Mucosa-Associated Lymphoid Tissue Lymphoma Associated with Serous Retinal Detachment.
abstract: We present a case of orbital mucosa-associated lymphoid tissue (MALT) lymphoma accompanied by a serous retinal detachment (SRD). A 44-year-old man who developed uveitis accompanied by a SRD in the right eye was referred to the Chiba National Hospital. B-mode ultrasonography and magnetic resonance imaging (MRI) showed a thickened choroidal membrane and a retrobulbar mass. Although topical steroid treatments improved the inflammation, the SRD did not improve. He was then referred to the Chiba University Hospital. Two months later, the retrobulbar mass had increased, and a partial resection biopsy combined with flow cytometry was performed. The final diagnosis was MALT lymphoma. After R-CHOP (rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisolone) chemotherapy, signs of the tumour could not be detected and the SRD was reduced. We conclude that the SRD was most likely due to the infiltration of lymphoma cells and also to choroidal circulatory disturbances. Retrobulbar malignant lymphomas associated with a SRD are very rare and difficult to diagnosis without biopsy, but because early diagnosis is helpful in deciding the appropriate therapy, we recommend partial biopsy.
authors.affiliation: Department of Ophthalmology and Visual Science.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Oshitari
authors.affiliation: Department of Ophthalmology and Visual Science.
authors.forename: Satomi
authors.initials: S
authors.lastname: Ota
authors.affiliation: Department of Ophthalmology and Visual Science.
authors.forename: Emi
authors.initials: E
authors.lastname: Ooka
authors.affiliation: Department of Molecular Pathology and.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kishimoto
authors.affiliation: Department of Diagnostic Pathology, Chiba University Graduate School of Medicine Chiba Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ota
authors.affiliation: Department of Ophthalmology and Visual Science.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Baba
authors.affiliation: Department of Ophthalmology and Visual Science.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Yamamoto
keywords: Chemotherapy; mucosa-associated lymphoid tissue lymphoma; retrobulbar; serous retinal detachment