title: Two new triterpenoids from the roots of Pinus densiflora.
abstract: Chemical investigation of the roots of Pinus densiflora led to the isolation of two new triterpenoids, (24S)-3β-methoxy-24,25-epoxy-lanost-9(11)-ene (1) and 29-acetoxy-3α-methoxyserrat-14-en-21α-ol (2), together with three known serratene-type triterpenoids (3-5) and four known diterpenoids (6-9). Their structures were determined by spectroscopic analyses.
authors.affiliation: a Chemical Biology Research Group , RIKEN Center for Sustainable Research Science , Wako , Japan.
authors.forename: Junnosuke
authors.initials: J
authors.lastname: Otaka
authors.affiliation: b Department of Applied Microbiology , Forestry and Forest Products Research Institute , Tsukuba , Japan.
authors.forename: Masabumi
authors.initials: M
authors.lastname: Komatsu
authors.affiliation: b Department of Applied Microbiology , Forestry and Forest Products Research Institute , Tsukuba , Japan.
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Miyazaki
authors.affiliation: a Chemical Biology Research Group , RIKEN Center for Sustainable Research Science , Wako , Japan.
authors.forename: Yushi
authors.initials: Y
authors.lastname: Futamura
authors.affiliation: a Chemical Biology Research Group , RIKEN Center for Sustainable Research Science , Wako , Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Osada
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004354:Drug Screening Assays, Antitumor / Q000379:methods; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D028223:Pinus / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes
keywords: Pinaceae; Pinus densiflora; roots; triterpenoid