title: Staged total knee arthroplasty for bilateral complex knee deformities from Kashin-Beck disease and skeletal dysplasia.
abstract: This study reported two cases of patients with Grade III Kashin-Beck disease (KBD) with skeletal dysplasia concomitant with complex knee deformity and functional limitation treated by staged total knee arthroplasty (TKA). Detailed pre-operative planning, bone resection, and soft tissue balancing in affected knees were performed in the surgeries in this report. The results demonstrated that TKA could correct lower limb alignment, alleviate knee pain, improve function, and provide good quality of life in people with KBD. Surgical efficacy is still lower compared with treatment for osteoarthritis; contributing factors include weak muscle strength, severe deformity and unequal length of the lower limb, weak extensor apparatus of the knee, and patient-specific factors.
authors.affiliation: Department of Orthopaedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China. Electronic address: lingming0114@163.com.
authors.forename: Ming
authors.initials: M
authors.lastname: Ling
authors.affiliation: Department of Orthopaedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
authors.forename: Xueyuan
authors.initials: X
authors.lastname: Wu
authors.affiliation: Department of Orthopaedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
authors.forename: Yanhai
authors.initials: Y
authors.lastname: Chang
authors.affiliation: Department of Orthopaedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
authors.forename: Xianghui
authors.initials: X
authors.lastname: Dong
authors.affiliation: Department of Orthopaedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
authors.forename: Zhengming
authors.initials: Z
authors.lastname: Sun
authors.affiliation: Department of Civil and Environmental Engineering, School of Engineering, The Hong Kong University of Science and Technology, Hong Kong, China.
authors.forename: Li
authors.initials: L
authors.lastname: Ling
authors.affiliation: Department of Orthopaedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
authors.forename: Shixun
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Orthopaedics, Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D005260:Female; D006801:Humans; D057767:Kashin-Beck Disease / Q000145:classification / Q000000981:diagnostic imaging / Q000601:surgery*; D007719:Knee Joint / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged
keywords: Arthroplasty; Kashin–Beck disease; Osteoarthritis; Skeletal dysplasia