title: Light-Triggered Assembly of Gold Nanoparticles for Photothermal Therapy and Photoacoustic Imaging of Tumors In Vivo.
abstract: Photocross-linkable Au nanoparticles are prepared through surface decoration of photolabile diazirine moieties. Both in vitro and in vivo studies indicate that the light-triggered cross-linking can dramatically shift the surface plasmon resonance of Au nanoparticles to near-infrared regions, which in consequence remarkably enhances their efficacy for photothermal therapy and photoacoustic imaging of tumors in vivo.
authors.affiliation: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.
authors.forename: Xiaju
authors.initials: X
authors.lastname: Cheng
authors.affiliation: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Sun
authors.affiliation: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.|Department of Chemistry and Chemical Engineering, Jining University, Qufu, 273155, P. R. China.
authors.forename: Ling
authors.initials: L
authors.lastname: Yin
authors.affiliation: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.
authors.forename: Zhifang
authors.initials: Z
authors.lastname: Chai
authors.affiliation: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.
authors.forename: Haibin
authors.initials: H
authors.lastname: Shi
authors.affiliation: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, 215123, China.|Institute of Chemistry Chinese Academy of Sciences, School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Mingyuan
authors.initials: M
authors.lastname: Gao
mesh_terms: D006046:Gold; D006801:Humans; D053768:Metal Nanoparticles; D009369:Neoplasms; D061088:Photoacoustic Techniques; D010789:Phototherapy
chemical_list: D006046:Gold
keywords: photoacoustic imaging; photocross-linking; photolabile Au nanoparticles; photothermal therapy