title: Does exercise training affect resting metabolic rate in adolescents with obesity?
abstract: We evaluated the hypothesis that resistance exercise training performed alone or in combination with aerobic exercise training would increase resting metabolic rate (RMR) relative to aerobic-only and nonexercising control groups. Postpubertal adolescents (N = 304) aged 14-18 years with obesity (body mass index (BMI) ≥ 95th percentile) or overweight (BMI ≥ 85th percentile + additional diabetes risk factor(s)) were randomized to 4 groups for 22 weeks: Aerobic exercise training, Resistance exercise training, Combined aerobic and resistance exercise training, or Control. All participants received dietary counselling targeting a daily energy deficit of 250 kcal. RMR was measured by indirect calorimetry and body composition by magnetic resonance imaging. There was no significant change in RMR in any group, in spite of significant within-group increases in fat-free mass in the Aerobic, Resistance, and Combined exercise training groups. RMR at baseline and 6 months were Aerobic: 1972 ± 38 and 1990 ± 41; Resistance: 2024 ± 37 and 1992 ± 41; Combined: 2023 ± 38 and 1995 ± 38; Control: 2075 ± 38 and 2073 ± 39 kcal/day (p > 0.05). There were no between-group differences in RMR after adjustment for total body weight or fat-free mass between groups over time. Per-protocol analyses including only participants with ≥70% adherence, and analyses stratified by sex, also showed no within- or between-group differences in RMR. In conclusion, despite an increase in fat-free mass in all exercise groups, 6 months of aerobic, resistance, or combined training with modest dietary restriction did not increase RMR compared with diet only in adolescents with obesity.
authors.affiliation: a School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.|b Werklund School of Education, University of Calgary, Calgary, AB T2N 1N4, Canada.
authors.forename: Angela S
authors.initials: AS
authors.lastname: Alberga
authors.affiliation: a School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.|c Institut de Recherche de l'Hôpital Montfort, Ottawa, ON K1K 0T1, Canada.
authors.forename: Denis
authors.initials: D
authors.lastname: Prud'homme
authors.affiliation: a School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.|d Departments of Medicine, Cardiac Sciences and Community Health Sciences, Faculties of Medicine and Kinesiology, University of Calgary, Calgary, AB T2T 5C7, Canada.|e Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Sigal
authors.affiliation: a School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.|f Healthy Active Living & Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada.
authors.forename: Gary S
authors.initials: GS
authors.lastname: Goldfield
authors.affiliation: f Healthy Active Living & Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada.
authors.forename: Stasia
authors.initials: S
authors.lastname: Hadjiyannakis
authors.affiliation: g Crabtree Laboratories, Royal Victoria Hospital, McGill University Health Center, Montreal, QC H3A 1A1, Canada.
authors.forename: Réjeanne
authors.initials: R
authors.lastname: Gougeon
authors.affiliation: e Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
authors.forename: Penny
authors.initials: P
authors.lastname: Phillips
authors.affiliation: e Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
authors.forename: Janine
authors.initials: J
authors.lastname: Malcolm
authors.affiliation: e Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.|h The Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, ON K1H 8L1, Canada.
authors.forename: George A
authors.initials: GA
authors.lastname: Wells
authors.affiliation: i Capital District Health Authority & Community Health and Epidemiology, Dalhousie University, Halifax, NS B3H 1V7, Canada.
authors.forename: Steve
authors.initials: S
authors.lastname: Doucette
authors.affiliation: j Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada.
authors.forename: Jinhui
authors.initials: J
authors.lastname: Ma
authors.affiliation: a School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.|e Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
authors.forename: Glen P
authors.initials: GP
authors.lastname: Kenny
mesh_terms: D050154:Adiposity; D000293:Adolescent; D041923:Adolescent Development; D017195:Adolescent Nutritional Physiological Phenomena; D001481:Basal Metabolism; D015992:Body Mass Index; D002153:Calorimetry, Indirect; D003131:Combined Modality Therapy; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000209:etiology; D004038:Diet, Reducing; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D024510:Muscle Development; D009864:Ontario / Q000453:epidemiology; D050177:Overweight / Q000178:diet therapy / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D063766:Pediatric Obesity / Q000178:diet therapy / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D055070:Resistance Training; D012307:Risk Factors
keywords: adolescents; aerobic exercise; dépense énergétique de repos; exercice aérobie; exercice contre résistance; jeunes; resistance exercise; resting energy expenditure; teenagers; youth