title: Depression screening with patient-targeted feedback in cardiology: DEPSCREEN-INFO randomised clinical trial.
abstract: International guidelines advocate depression screening in patients with coronary heart disease (CHD) and other chronic illnesses, but evidence is lacking.
  
  
  
  To test the differential efficacy of written patient-targeted feedback v. no written patient feedback after depression screening.
  
  
  
  Patients with CHD or hypertension from three cardiology settings were randomised and screened for depression (ClinicalTrials.gov Identifier: NCT01879111). Compared with the control group, where only cardiologists received written feedback, in the intervention group both cardiologists and patients received written feedback regarding depression status. Depression severity was measured 1 month (primary outcome) and 6 months after screening.
  
  
  
  The control group (n = 220) and the patient-feedback group (n = 155) did not differ in depression severity 1 month after screening. Six months after screening, the patient-feedback group showed significantly greater improvements in depression severity and was twice as likely to seek information about depression compared with the control group.
  
  
  
  Patient-targeted feedback in addition to screening has a significant but small effect on depression severity after 6 months and may encourage patients to take an active role in the self-management of depression.
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany b.loewe@uke.de.
authors.forename: Bernd
authors.initials: B
authors.lastname: Löwe
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Blankenberg
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany.
authors.forename: Karl
authors.initials: K
authors.lastname: Wegscheider
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany.
authors.forename: Hans-Helmut
authors.initials: HH
authors.lastname: König
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany.
authors.forename: Dirk
authors.initials: D
authors.lastname: Walter
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany.
authors.forename: Alexandra M
authors.initials: AM
authors.lastname: Murray
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Gierk
authors.affiliation: Bernd Löwe, MD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg; Stefan Blankenberg, MD, University Heart Centre, University Medical Centre Hamburg-Eppendorf, Hamburg; Karl Wegscheider, PhD, Department of Biostatistics and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg; Hans-Helmut König, MD MPH, Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg; Dirk Walter, MD, Cardiologicum Hamburg, Hamburg; Alexandra M. Murray, DPhil, Benjamin Gierk, MSc, Sebastian Kohlmann, PhD, Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Kohlmann
mesh_terms: D015897:Comorbidity; D003327:Coronary Disease / Q000453:epidemiology; D003863:Depression / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D005246:Feedback; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012648:Self Care; D012720:Severity of Illness Index