title: [Mesocolic excision for colonic adenocarcinoma].
abstract: On the same principle than total mesorectal excision in rectal cancer, the effect of complete mesocolic excision on short and long-term outcomes is actually evaluated for colonic adenocarcinoma. This method, usually performed for left colectomy, offers a surgical specimen of higher quality, with a larger number of lymph nodes harvested. For right colectomy, surgical specifications make it less common complete mesocolic excision and conventional surgery offer comparable outcomes, as regards to postoperative morbidity and mortality rates. No differences are identified between laparoscopic and open surgery. On oncologic outcomes, only two studies report a higher free-disease survival after complete mesocolic excision. Then, there is evidence that complete mesocolic excision offers a higher rate of specimen with extensive lymph node resection, without increased morbidity rate. However, there is limited evidence that it leads to improve long-term oncological outcomes.
authors.affiliation: Hôpital Saint-Antoine, service de chirurgie générale et digestive, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France; Pierre & Marie Curie, université Paris VI, faculté de médecine, Paris, France.
authors.forename: Clotilde
authors.initials: C
authors.lastname: Debove
authors.affiliation: Hôpital Saint-Antoine, service de chirurgie générale et digestive, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France; Pierre & Marie Curie, université Paris VI, faculté de médecine, Paris, France. Electronic address: jeremie.lefevre@aphp.fr.
authors.forename: Jérémie H
authors.initials: JH
authors.lastname: Lefèvre
authors.affiliation: Hôpital Saint-Antoine, service de chirurgie générale et digestive, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France; Pierre & Marie Curie, université Paris VI, faculté de médecine, Paris, France.
authors.forename: Yann
authors.initials: Y
authors.lastname: Parc
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D003082:Colectomy / Q000379:methods / Q000401:mortality; D003110:Colonic Neoplasms / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008646:Mesocolon / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications / Q000401:mortality; D016896:Treatment Outcome
keywords: Adénocarcinome colique; Colon cancer; Complete mesocolic excision; Curage ganglionnaire; Exérèse totale du mésocôlon; Lymph node resection