title: RETRACTED: MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
  
  This article has been retracted at the request of the Editor-in-Chief.
  
  An Expression of Concern for this article was previously published while an investigation was conducted (see related editorial: https://doi.org/10.1016/j.biopha.2022.113812). This retraction notice supersedes the Expression of Concern published earlier.
  
  Concern was raised about the reliability of the flow cytometry data in Figure 9, with suspected image similarities reported between the ‘miR-138 mimic’ and ‘siRNA hTERT’ groups, as detailed here: https://pubpeer.com/publications/983120063E7603EBA705B85BBF77F5; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Independent analysis confirmed this finding and identified additional suspected image duplications within Figure 9. The journal requested the corresponding author comment on these concerns and provide the associated raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.
authors.affiliation: Department of Dermatology, Cangzhou Central Hospital, Cangzhou 061001, PR China. Electronic address: drfeng0819@126.com.
authors.forename: Shi-Jun
authors.initials: SJ
authors.lastname: Feng
authors.affiliation: Department of Dermatology, Affiliated Hospital of Hebei University, Baoding 071000, PR China.
authors.forename: Rui-Qi
authors.initials: RQ
authors.lastname: Chu
authors.affiliation: Department of Dermatology, Cangzhou Central Hospital, Cangzhou 061001, PR China.
authors.forename: Jing
authors.initials: J
authors.lastname: Ma
authors.affiliation: Department of Dermatology, Cangzhou Central Hospital, Cangzhou 061001, PR China.
authors.forename: Zheng-Xiang
authors.initials: ZX
authors.lastname: Wang
authors.affiliation: Department of Dermatology, Cangzhou Central Hospital, Cangzhou 061001, PR China.
authors.forename: Guang-Jing
authors.initials: GJ
authors.lastname: Zhang
authors.affiliation: Department of Dermatology, Cangzhou Central Hospital, Cangzhou 061001, PR China.
authors.forename: Xiu-Fang
authors.initials: XF
authors.lastname: Yang
authors.affiliation: Department of Dermatology, Jingzhou Central Hospital, Jingzhou 434020, PR China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Song
authors.affiliation: Department of Dermatology, Jingzhou Central Hospital, Jingzhou 434020, PR China.
authors.forename: Yun-Yi
authors.initials: YY
authors.lastname: Ma
mesh_terms: D000328:Adult; D017209:Apoptosis; D016022:Case-Control Studies; D002460:Cell Line; D049109:Cell Proliferation; D005260:Female; D059585:G1 Phase Cell Cycle Checkpoints; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D053537:Keratin-17 / Q000235:genetics / Q000378:metabolism*; D015603:Keratinocytes / Q000378:metabolism* / Q000473:pathology; D008297:Male; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*; D011565:Psoriasis / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D034622:RNA Interference; D015398:Signal Transduction; D012867:Skin / Q000378:metabolism* / Q000473:pathology; D019098:Telomerase / Q000235:genetics / Q000378:metabolism; D013997:Time Factors; D014162:Transfection; D055815:Young Adult
chemical_list: D053537:Keratin-17; C546110:MIRN138 microRNA, human; D035683:MicroRNAs; C509186:TERT protein, human; D019098:Telomerase
keywords: Apoptosis; HaCaT cells; Keratin 17; MicroRNA-138; Proliferation; Psoriasis vulgaris; hTERT