title: Helminth glycomics - glycan repertoires and host-parasite interactions.
abstract: Glycoproteins and glycolipids of parasitic helminths play important roles in biology and host-parasite interaction. This review discusses recent helminth glycomics studies that have been expanding our insights into the glycan repertoire of helminths. Structural data are integrated with biological and immunological observations to highlight how glycomics advances our understanding of the critical roles that glycans and glycan motifs play in helminth infection biology. Prospects and challenges in helminth glycomics and glycobiology are discussed.
authors.affiliation: Parasite Glycobiology Group, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: c.h.hokke@lumc.nl.
authors.forename: Cornelis H
authors.initials: CH
authors.lastname: Hokke
authors.affiliation: Parasite Glycobiology Group, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Angela
authors.initials: A
authors.lastname: van Diepen
mesh_terms: D000818:Animals; D006017:Glycolipids / Q000032:analysis*; D054794:Glycomics; D006023:Glycoproteins / Q000032:analysis*; D006376:Helminths / Q000737:chemistry*; D006790:Host-Parasite Interactions
chemical_list: D006017:Glycolipids; D006023:Glycoproteins
keywords: Glycan antigen; Glycan array; Glycans; Helminths; Mass spectrometry; Schistosome