title: The B3 conundrum-the radiologists' perspective.
abstract: The management of B3 lesions is both controversial and complicated. There have been recent publications regarding how best to manage this heterogeneous group particularly in light of the Marmot Review and with the advent of vacuum-assisted biopsy technique. It is recognized that B3 lesions on core biopsy can be upgraded to malignancy in up to one-third of cases, but this is predominantly to ductal carcinoma in situ or low-grade invasive tumours. The upgrade rate is mainly associated with B3 lesions with epithelial atypia. This review summarizes the current management and focuses on the proposed future management of these B3 lesions.
authors.affiliation: 1 Breast Unit, Level 1 Chancellor Wing, St James's Hospital, Leeds Teaching Hospital NHS Trust, Leeds, UK.
authors.forename: Nisha
authors.initials: N
authors.lastname: Sharma
authors.affiliation: 2 Department of Breast imaging, St George's Hospital, London, UK.
authors.forename: Louise S
authors.initials: LS
authors.lastname: Wilkinson
authors.affiliation: 3 Department of Breast Pathology, King's College London and Guy's Hospital, London, UK.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Pinder
mesh_terms: D001707:Biopsy, Needle; D001940:Breast / Q000000981:diagnostic imaging / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D008327:Mammography / Q000379:methods*; D000072177:Radiologists