title: Insertion of Arynes into P-O Bonds: One-Step Simultaneous Construction of C-P and C-O Bonds.
abstract: The insertion of arynes into P-O bonds for the preparation of o-hydroxy-substituted arylphosphine oxides, -phosphinates, and -phosphonates is described. This novel reaction leads to the simultaneous formation of C-P and C-O bonds in one step with good yields and regioselectivities under mild and transition-metal-free conditions. The easy follow-up transformations of the resulting o-hydroxyl group extend these reactions to the facile construction of other ortho-substituted arylphosphorus compounds.
authors.affiliation: School of Pharmaceutical Sciences and Innovative Drug Research Centre , Chongqing University , 55 Daxuecheng South Road, Shapingba, Chongqing 401331, P. R. China.
authors.forename: Na
authors.initials: N
authors.lastname: Qi
authors.affiliation: School of Pharmaceutical Sciences and Innovative Drug Research Centre , Chongqing University , 55 Daxuecheng South Road, Shapingba, Chongqing 401331, P. R. China.
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.affiliation: School of Pharmaceutical Sciences and Innovative Drug Research Centre , Chongqing University , 55 Daxuecheng South Road, Shapingba, Chongqing 401331, P. R. China.
authors.forename: Srinivasa Rao
authors.initials: SR
authors.lastname: Allu
authors.affiliation: School of Pharmaceutical Sciences and Innovative Drug Research Centre , Chongqing University , 55 Daxuecheng South Road, Shapingba, Chongqing 401331, P. R. China.
authors.forename: Jiangsheng
authors.initials: J
authors.lastname: Gao
authors.affiliation: School of Pharmaceutical Sciences and Innovative Drug Research Centre , Chongqing University , 55 Daxuecheng South Road, Shapingba, Chongqing 401331, P. R. China.
authors.forename: Jian
authors.initials: J
authors.lastname: Guo
authors.affiliation: School of Pharmaceutical Sciences and Innovative Drug Research Centre , Chongqing University , 55 Daxuecheng South Road, Shapingba, Chongqing 401331, P. R. China.
authors.forename: Yun
authors.initials: Y
authors.lastname: He