title: The Impact of Emerging Infectious Diseases on Chinese Blood Safety.
abstract: Emerging infectious diseases (EIDs) have always been one of the major threats to public health. Although the implementation of mandatory testing for 4 classical transfusion-transmitted infectious-human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and syphilis-has reduced the transfusion risk of these pathogens, the potential threat of various EID agents and their constantly evolving variants to blood safety in China is not fully understood. This review presents 9 representative EID agents that are autochthonous and epidemic nationally or regionally in China. The epidemiologic status and distribution of these EID agents among donors and/or healthy populations are summarized. The potential risks of these EID agents to blood safety are discussed. The review also explores strategies to strengthen hemovigilance systems and studies to further evaluate the impact of EID agents on blood safety.
authors.affiliation: Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, Sichuan, China.
authors.forename: Miao
authors.initials: M
authors.lastname: He
authors.affiliation: Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, Sichuan, China.
authors.forename: Jingxing
authors.initials: J
authors.lastname: Wang
authors.affiliation: Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, Sichuan, China.
authors.forename: Limin
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.affiliation: West China School of Public Health, Sichuan University, Chengdu, Sichuan, China. Electronic address: zengpeibin@live.cn.
authors.forename: Peibin
authors.initials: P
authors.lastname: Zeng
mesh_terms: D001782:Blood Donors / Q000600:supply & distribution; D058731:Blood Safety / Q000379:methods / Q000592:standards / Q000706:statistics & numerical data; D001803:Blood Transfusion / Q000592:standards / Q000706:statistics & numerical data*; D017848:Blood-Borne Pathogens; D002681:China / Q000453:epidemiology; D021821:Communicable Diseases, Emerging / Q000453:epidemiology*; D006801:Humans; D012307:Risk Factors
keywords: Chinese blood safety; Emerging infectious diseases; Transfusion-transmitted infectious