title: Synthesis of Polyfunctional Pyridines via Copper-Catalyzed Oxidative Coupling Reactions.
abstract: An efficient and concise approach for the synthesis of polysubstituted pyridines has been achieved through copper-catalyzed oxidative sp3C-H coupling of oxime acetates with toluene derivatives. Besides, benzylamine and p-toluenesulfonylhydrazone were also introduced to react with oxime acetates to enrich the diversity of this synthetic method. These transformations provide highly flexible and facile preparation of substituted pyridines and thus are useful in practical synthesis.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University , Gansu, Lanzhou 730000, People's Republic of China.
authors.forename: Yajie
authors.initials: Y
authors.lastname: Fu
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University , Gansu, Lanzhou 730000, People's Republic of China.
authors.forename: Panpan
authors.initials: P
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University , Gansu, Lanzhou 730000, People's Republic of China.
authors.forename: Xin
authors.initials: X
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University , Gansu, Lanzhou 730000, People's Republic of China.
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
authors.affiliation: State Key Laboratory for Oxo Synthesis and Selective Oxidation, Suzhou Research Institute of LICP, Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences , Lanzhou 730000, People's Republic of China.
authors.forename: Xu
authors.initials: X
authors.lastname: Meng
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University , Gansu, Lanzhou 730000, People's Republic of China.
authors.forename: Baohua
authors.initials: B
authors.lastname: Chen