title: Rhythmic wrist movements facilitate the soleus H-reflex and non-voluntary air-stepping in humans.
abstract: Neural coupling between the upper and lower limbs during human walking is supported by modulation of cross-limb reflexes and the presence of rhythmic activity in the proximal arm muscles. Nevertheless, the involvement of distal arm muscles in cyclic movements and sensorimotor neuromodulation is also suggested given their step-synchronized activation in many locomotor-related tasks (e.g., swimming, skiing, climbing, cycling, crawling, etc.). Here we investigated the effect of rhythmic wrist movements, separately and in conjunction with arm swinging, on the characteristics of non-voluntary cyclic leg movements evoked by muscle vibration in a gravity neutral position and on the soleus H-reflex of the stationary legs. For the H-reflex modulation, five conditions were compared: stationary arms, voluntary alternating upper limb swinging, combined upper limb and wrist motion, wrist movements only and motion of the upper limbs with addition of load. Rhythmic wrist movements significantly facilitated the amplitude of non-voluntary leg oscillations, including ankle joint oscillations, and the H-reflex. The latter effect was related to rhythmicity of wrist motion rather than to a simple extra tension in the upper limb muscles (a kind of the Jendrassik manoeuvre) since adding resistance to arm oscillations (without flexion-extension in the wrist joint) had an opposite inhibitory effect on the H-reflex. Our results further support the existence of connections between the distal parts of the upper and lower extremities at the neural level, suggesting that wrist joint movements can be an important component of motor neurorehabilitation.
authors.affiliation: Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia. Electronic address: solopova@iitp.ru.
authors.forename: Irina A
authors.initials: IA
authors.lastname: Solopova
authors.affiliation: Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.
authors.forename: Victor A
authors.initials: VA
authors.lastname: Selionov
authors.affiliation: Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia; Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russia.
authors.forename: Egor O
authors.initials: EO
authors.lastname: Blinov
authors.affiliation: Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.
authors.forename: Dmitri S
authors.initials: DS
authors.lastname: Zhvansky
authors.affiliation: Laboratory of Neuromotor Physiology, Santa Lucia Foundation, Rome, Italy.
authors.forename: Yury P
authors.initials: YP
authors.lastname: Ivanenko
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006181:H-Reflex; D006801:Humans; D007866:Leg / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009068:Movement; D018482:Muscle, Skeletal / Q000502:physiology*; D010507:Periodicity; D012149:Restraint, Physical; D014953:Wrist / Q000502:physiology*; D055815:Young Adult
keywords: Arm-leg coordination; H-reflex; Hand-foot neural coupling; Quadrupedal human locomotion; Rhythmogenesis