title: Synthesis of Chiral Vicinal Diamines by Silver(I)-Catalyzed Enantioselective Aminolysis of N-Tosylaziridines.
abstract: The kinetic resolution of 2-aryl-N-tosylaziridines and the asymmetric desymmetrization of meso-N-tosylaziridines by ring openings with various primary and secondary anilines, and aliphatic amines as nucleophile have been realized by using a single silver(I)/chiral diphosphine complex as catalyst for the first time. The simple starting materials, broad scope, and easy scalability render this protocol a practical way to chiral vicinal diamine derivatives.
authors.affiliation: Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, 1 East Beijing Road, Wuhu, Anhui, 241000, China.
authors.forename: Zhuo
authors.identifier: 0000-0002-9878-8814
authors.initials: Z
authors.lastname: Chai
authors.affiliation: Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, 1 East Beijing Road, Wuhu, Anhui, 241000, China.
authors.forename: Pei-Jun
authors.initials: PJ
authors.lastname: Yang
authors.affiliation: Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, 1 East Beijing Road, Wuhu, Anhui, 241000, China.
authors.forename: Hu
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, 1 East Beijing Road, Wuhu, Anhui, 241000, China.|State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, P.R. China.
authors.forename: Shaowu
authors.initials: S
authors.lastname: Wang
authors.affiliation: Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, 1 East Beijing Road, Wuhu, Anhui, 241000, China.
authors.forename: Gaosheng
authors.initials: G
authors.lastname: Yang
keywords: amines; aziridines; desymmetrization; kinetic resolution; silver