title: [Contrast sensitivity analysis about fundus changes of hypertensive disorders complicating pregnancy].
abstract: To observe corrected visual acuity and contrast sensitivity (CS) in patients with hypertensive disorders complicating pregnancy accompanied by fundus changes.  Methods: Ninety-eight patients with hypertensive disorders complicating pregnancy and 50 healthy pregnant women underwent eye examination, including corrected visual acuity and fundus examination, and CS. Differences in corrected visual acuity and contrast sensitivity between the 2 groups were analyzed with two independent samples t-test analysis, while correlation between vision and contrast sensitivity in patients was evaluated by using spearman correlation test. Difference in CS was compared between the early and advanced stage of fundus diseases.  Results: Corrected visual acuity and contrast sensitivity in patient with hypertensive disorders complicating pregnancy were lower than that in the control group (P<0.01). Corrected visual acuity in patients was associated with contrast sensitivity at variously spatial frequencies (P<0.01), showing the most correlation in contrast sensitivity at 6 of spatial frequency (r=0.87). Compared with the early stage, the CS in the advanced patients with fundus diseases was decreased (P<0.01).  Conclusion: The visual acuity and contrast sensitivity in patient with hypertensive disorders complicating pregnancy are reduced. The CS (6.0 c/d) has the largest correlation with corrected visual acuity. Comparing with the visual acuity, contrast sensitivity can be more comprehensive in evaluation of retinal function damage in patients with hypertensive disorders complicating pregnancy.
authors.affiliation: Department of Ophthalmology, Cangzhou Central Hospital, Cangzhou Hebei 061000, China wangzhixue5@163.com.
authors.forename: Zhixue
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Cangzhou Central Hospital, Cangzhou Hebei 061000, China.
authors.forename: Wenying
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Cangzhou Central Hospital, Cangzhou Hebei 061000, China.
authors.forename: Fengmei
authors.initials: F
authors.lastname: Han
mesh_terms: D000328:Adult; D015350:Contrast Sensitivity / Q000502:physiology*; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D006973:Hypertension / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D012164:Retinal Diseases / Q000150:complications* / Q000209:etiology*; D014786:Vision Disorders / Q000209:etiology* / Q000503:physiopathology*; D014792:Visual Acuity / Q000502:physiology*