title: The shady side of leaf development: the role of the REVOLUTA/KANADI1 module in leaf patterning and auxin-mediated growth promotion.
abstract: Leaves are present in all land plants and are specialized organs for light harvesting. They arise at the flanks of the shoot apical meristem (SAM), and develop into lamina structures that exhibit adaxial/abaxial (upper/lower side of the leaf) polarity. At the molecular level, an intricate regulatory network determines ad-/abaxial polarity in Arabidopsis thaliana leaves, where the Class III Homeodomain Leucine Zipper (HD-ZIPIII) and KANADI (KAN) proteins are key mediators. The HD-ZIPIII REVOLUTA (REV) is expressed in the adaxial domain of lateral organs, whereas KAN1 is involved in abaxial differentiation. The REV/KAN1 module directly and antagonistically regulates the expression of several genes involved in shade-induced growth and auxin biosynthetic enzymes.
authors.affiliation: European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
authors.forename: Paz
authors.initials: P
authors.lastname: Merelo
authors.affiliation: Copenhagen Plant Science Centre, Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.
authors.forename: Esther Botterweg
authors.initials: EB
authors.lastname: Paredes
authors.affiliation: European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany. Electronic address: heisler@embl.de.
authors.forename: Marcus G
authors.initials: MG
authors.lastname: Heisler
authors.affiliation: Copenhagen Plant Science Centre, Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark. Electronic address: wenkel@plen.ku.dk.
authors.forename: Stephan
authors.initials: S
authors.lastname: Wenkel
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000378:metabolism*; D018515:Plant Leaves / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids