title: Biological Activities of Extracts from Loquat (Eriobotrya japonica Lindl.): A Review.
abstract: Loquat (Eriobotrya japonicaLindl.) is a subtropical fruit tree with high medicinal value native to China. Different organs of loquat have been used historically as folk medicines and this has been recorded in Chinese history for thousands of years. Research shows that loquat extracts contain many antioxidants, and different extracts exhibit bioactivity capable of counteracting inflammation, diabetes, cancer, bacterial infection, aging, pain, allergy and other health issues. Bioactive compounds such as phenolics and terpenoids have been isolated and characterized to provide a better understanding of the chemical mechanisms underlying the biological activities of loquat extracts. As the identification of compounds progresses, studies investigating the in vivo metabolism, bioavailability, and structure-activity relationships, as well as potential toxicity of loquat extracts in animal or cell models are receiving more attention. In addition, genetic studies and breeding of loquat germplasms for high contents of health-benefiting compounds may provide new insight for the loquat industry and research. This review is focused on the main medicinal properties reported and the possible pharmaceutically active compounds identified in different loquat extracts.
authors.affiliation: Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China. yilongliu@zju.edu.cn.
authors.forename: Yilong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China. nawen2007@163.com.|Catch Bio-Science & Technology Co., Ltd., 5F of Building G, No. 1 North Guotai Road, Zhangjiagang 215600, China. nawen2007@163.com.
authors.forename: Wenna
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China. chjxu@zju.edu.cn.|The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, China. chjxu@zju.edu.cn.
authors.forename: Changjie
authors.initials: C
authors.lastname: Xu
authors.affiliation: Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China. xianli@zju.edu.cn.|The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang University, Zijingang Campus, Hangzhou 310058, China. xianli@zju.edu.cn.
authors.forename: Xian
authors.initials: X
authors.lastname: Li
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D031983:Eriobotrya / Q000737:chemistry*; D006801:Humans; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000975:Antioxidants; D010936:Plant Extracts
keywords: Eriobotrya japonica Lindl.; bioactive compounds; bioactivities