title: Total Synthesis of Tetraketide and Cryptorigidifoliol I via a Sequential Allylation Strategy.
abstract: A unified and efficient synthetic route for both tetraketide (1) and cryptorigidifoliol I (2) has been devised successfully from commercially available starting materials in 11 and 17 steps, with 16% and 11% overall yields, respectively. Highlights of the syntheses involved sequential Lewis acid-catalyzed highly regio- and diastereoselective allylations and intramolecular Mitsunobu lactonization.
authors.affiliation: Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology , Hyderabad 500 007, India.|Academy of Scientific and Innovative Research , New Delhi 110025, India.
authors.forename: Birakishore
authors.initials: B
authors.lastname: Padhi
authors.affiliation: Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology , Hyderabad 500 007, India.|Academy of Scientific and Innovative Research , New Delhi 110025, India.
authors.forename: G Sudhakar
authors.initials: GS
authors.lastname: Reddy
authors.affiliation: Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology , Hyderabad 500 007, India.|Academy of Scientific and Innovative Research , New Delhi 110025, India.
authors.forename: Debendra K
authors.initials: DK
authors.lastname: Mohapatra
mesh_terms: D002384:Catalysis; D003512:Cyclohexanones / Q000138:chemical synthesis* / Q000737:chemistry; D004187:Disaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D019684:Magnoliopsida / Q000737:chemistry; D015394:Molecular Structure; D061065:Polyketides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D003512:Cyclohexanones; D004187:Disaccharides; D061065:Polyketides; C000620034:cryptorigidifoliol I; C413265:tetraketide