title: Genetic evidence for an East Asian origin of Chinese Muslim populations Dongxiang and Hui.
abstract: There is a long-going debate on the genetic origin of Chinese Muslim populations, such as Uygur, Dongxiang, and Hui. However, genetic information for those Muslim populations except Uygur is extremely limited. In this study, we investigated the genetic structure and ancestry of Chinese Muslims by analyzing 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations in Gansu province. Both genetic distance and Bayesian-clustering methods showed significant genetic homogeneity between the two Muslim populations and East Asian populations, suggesting a common genetic ancestry. Our analysis found no evidence of substantial gene flow from Middle East or Europe into Dongxiang and Hui people during their Islamization. The dataset generated in present study are also valuable for forensic identification and paternity tests in China.
authors.affiliation: Key Laboratory of Evidence Science of Gansu Province, Gansu Institute of Political Science and Law, Lanzhou, 730070, China.
authors.forename: Hong-Bing
authors.initials: HB
authors.lastname: Yao
authors.affiliation: State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, 200433, China.|Department of Archaeogenetics and Eurasia3angle research group, Max Planck Institute for the Science of Human History, Kahlaische Straße 10, 07745 Jena, Germany.
authors.forename: Chuan-Chao
authors.initials: CC
authors.lastname: Wang
authors.affiliation: Key Laboratory of Evidence Science of Gansu Province, Gansu Institute of Political Science and Law, Lanzhou, 730070, China.
authors.forename: Xiaolan
authors.initials: X
authors.lastname: Tao
authors.affiliation: Key Laboratory of Forensic Genetics, Institute of Forensic Science, Ministry of Public Security, Beijing, 100038, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Shang
authors.affiliation: State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, 200433, China.
authors.forename: Shao-Qing
authors.initials: SQ
authors.lastname: Wen
authors.affiliation: School of Medicine, Xi'an Jiaotong University, Xi'an, 710061, China.
authors.forename: Bofeng
authors.initials: B
authors.lastname: Zhu
authors.affiliation: Key Laboratory of High Altitude Environment and Gene Related to Disease of Tibet, Ministry of Education, Tibet University for Nationalities, Xianyang, Shaanxi, 712082, China.
authors.forename: Longli
authors.initials: L
authors.lastname: Kang
authors.affiliation: State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, 200433, China.|CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
authors.forename: Li
authors.initials: L
authors.lastname: Jin
authors.affiliation: State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, 200433, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Li
mesh_terms: D002681:China; D016000:Cluster Analysis; D005006:Ethnicity / Q000235:genetics*; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D007514:Islam; D018895:Microsatellite Repeats
chemical_list: D005819:Genetic Markers