title: Fetal hypothyroidism induced by maternal anti-TSH receptor blocking antibodies and complicated by polyhydramnios despite the absence of goiter. Treatment by intra-amniotic injections of levothyroxine.
authors.affiliation: Pôle couple enfant, département de pédiatrie, CHU des Alpes, CS 10217, 38043 Grenoble cedex 9, France.
authors.forename: Adèle
authors.initials: A
authors.lastname: Menut-Ruel
authors.affiliation: Service d'endocrinologie, CHU des Alpes, CS 10217, 38043 Grenoble cedex 9, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Barthod
authors.affiliation: Pôle de biologie, institut de biologie et de pathologie, CHU des Alpes, CS 10217, 38043 Grenoble cedex 9, France; Laboratoire de radio analyses, service de médecine nucléaire, centre hospitalier métropole Savoie, 73000 Chambéry, France.
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Gauchez
authors.affiliation: Pôle couple enfant, département de pédiatrie, CHU des Alpes, CS 10217, 38043 Grenoble cedex 9, France.
authors.forename: Clémentine
authors.initials: C
authors.lastname: Dupuis
authors.affiliation: Pôle de biologie, CHU de Lyon-Sud, CARMEN-Inserm U 1060, 69000 Lyon, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Charrie
authors.affiliation: Pôle couple enfant, département de gynécologie obstétrique, centre hospitalier métropole Savoie, 73000 Chambéry, France.
authors.forename: Claire
authors.initials: C
authors.lastname: Dubois
authors.affiliation: Endocrinologue libérale, 27, allée Albert-Sylvestre, 73000 Chambéry, France.
authors.forename: Agnès
authors.initials: A
authors.lastname: Leriche
authors.affiliation: Echographiste libéral, 27, allée Albert-Sylvestre, 73000 Chambéry, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Polverelli
authors.affiliation: Pôle couple enfant, département de génétique et procréation, centre pluridisciplinaire de diagnostic prénatal, CHU des Alpes, CS 10217, 38043 Grenoble cedex 9, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Althuser
authors.affiliation: Pôle couple enfant, département de génétique et procréation, centre pluridisciplinaire de diagnostic prénatal, CHU des Alpes, CS 10217, 38043 Grenoble cedex 9, France.
authors.forename: Pierre Simon
authors.initials: PS
authors.lastname: Jouk
authors.affiliation: Service d'endocrinologie, CHU des Alpes, CS 10217, 38043 Grenoble cedex 9, France. Electronic address: OlivierChabre@chu-grenoble.fr.
authors.forename: Olivier
authors.initials: O
authors.lastname: Chabre
mesh_terms: D000328:Adult; D000650:Amnion / Q000187:drug effects; D000653:Amniotic Fluid / Q000737:chemistry / Q000276:immunology; D005260:Female; D005315:Fetal Diseases / Q000276:immunology*; D005865:Gestational Age; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000196:embryology* / Q000276:immunology; D018828:Immunoglobulins, Thyroid-Stimulating / Q000032:analysis / Q000276:immunology*; D008297:Male; D008431:Maternal-Fetal Exchange / Q000276:immunology; D006831:Polyhydramnios; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D011256:Pregnancy Outcome; D013972:Thyrotropin / Q000032:analysis; D013974:Thyroxine / Q000008:administration & dosage* / Q000032:analysis; D014284:Triiodothyronine / Q000031:analogs & derivatives / Q000032:analysis; D016216:Ultrasonography, Prenatal
chemical_list: D018828:Immunoglobulins, Thyroid-Stimulating; C094372:thyrotropin-binding inhibitory immunoglobulin; D014284:Triiodothyronine; C040407:3,3',5-triiodothyronamine; D013972:Thyrotropin; D013974:Thyroxine