title: [Big data and their perspectives in radiation therapy].
abstract: The concept of big data indicates a change of scale in the use of data and data aggregation into large databases through improved computer technology. One of the current challenges in the creation of big data in the context of radiation therapy is the transformation of routine care items into dark data, i.e. data not yet collected, and the fusion of databases collecting different types of information (dose-volume histograms and toxicity data for example). Processes and infrastructures devoted to big data collection should not impact negatively on the doctor-patient relationship, the general process of care or the quality of the data collected. The use of big data requires a collective effort of physicians, physicists, software manufacturers and health authorities to create, organize and exploit big data in radiotherapy and, beyond, oncology. Big data involve a new culture to build an appropriate infrastructure legally and ethically. Processes and issues are discussed in this article.
authors.affiliation: Centre Paul-Strauss, service de radiothérapie, 3, rue de la Porte-de-l'Hôpital, BP 30042, 67065 Strasbourg cedex, France. Electronic address: seb.guihard@gmail.com.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Guihard
authors.affiliation: Centre Lacassagne, service de radiothérapie, 227, avenue de la Lanterne, 06200 Nice, France.
authors.forename: Juliette
authors.initials: J
authors.lastname: Thariat
authors.affiliation: Centre Paul-Strauss, service de radiothérapie, 3, rue de la Porte-de-l'Hôpital, BP 30042, 67065 Strasbourg cedex, France.
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Clavier
mesh_terms: D003625:Data Collection / Q000941:ethics / Q000331:legislation & jurisprudence / Q000379:methods; D057225:Data Mining / Q000379:methods; D016208:Databases, Factual / Q000941:ethics / Q000331:legislation & jurisprudence / Q000706:statistics & numerical data*; D003952:Diagnostic Imaging / Q000706:statistics & numerical data; D023281:Genomics; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000532:radiotherapy*; D058958:Organs at Risk / Q000528:radiation effects; D010817:Physician-Patient Relations; D018787:Radiation Oncology / Q000706:statistics & numerical data*; D011878:Radiotherapy / Q000009:adverse effects / Q000706:statistics & numerical data
keywords: Big data; Cancer; Données patient; Métadonnées; Oncologie; Oncology; Ontologie; Ontology; Patient-reported outcome; Radiotherapy; Radiothérapie