title: Pulmonary hyalinizing granuloma presenting with dysphagia: a rare presentation.
abstract: A 25-year-old man presented with a 2-month history of dysphagia and past history of pulmonary and intestinal tuberculosis. A barium swallow showed a point of constriction 42 mm above the gastroesophageal junction. Computed tomography revealed large opacities in bilateral lung fields, encroaching more on the esophagus. The lesion progressively compressed the esophagus as it moved inferiorly. A right posterolateral thoracotomy was performed for sub-anatomical resection of the mass. A biopsy revealed homogenous whirling hyalinized collagen fibers, highly suggestive of pulmonary hyalinizing granuloma, with no evidence of malignancy. Pulmonary hyalinizing granuloma should be considered in the differential diagnosis of longstanding dysphagia.
authors.affiliation: 1 Section of Cardiothoracic Surgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Fazal
authors.initials: F
authors.lastname: Khan
authors.affiliation: 2 Medical College, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Arsalan
authors.initials: A
authors.lastname: Hamid
authors.affiliation: 3 Liaquat National Hospital, Karachi, Pakistan.
authors.forename: Benish
authors.initials: B
authors.lastname: Fatima
authors.affiliation: 1 Section of Cardiothoracic Surgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Shiraz
authors.initials: S
authors.lastname: Hashmi
authors.affiliation: 1 Section of Cardiothoracic Surgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Saulat
authors.initials: S
authors.lastname: Fatimi
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001466:Barium Sulfate / Q000008:administration & dosage; D001706:Biopsy; D003287:Contrast Media / Q000008:administration & dosage; D003679:Deglutition; D003680:Deglutition Disorders / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D003937:Diagnosis, Differential; D015769:Granuloma, Respiratory Tract / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D006818:Hyalin; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D011237:Predictive Value of Tests; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media; D001466:Barium Sulfate
keywords: Deglutition disorders; Diagnosis; Granuloma; Lung diseases; Tuberculosis; differential; pulmonary