title: Resection planning in extratemporal epilepsy surgery using 3D multimodality imaging and intraoperative MRI.
abstract: Surgical resection in non-lesional, extratemporal epilepsy, informed by stereoEEG recordings, is challenging. There are no clear borders of resection, and the surgeon is often operating in deep areas of the brain that are difficult to access. We present a technical note where 3D multimodality image integration in EpiNavTMis used to build a planned resection model, based on a previous intracranial EEG evaluation. Intraoperative MRI is then used to ensure a complete resection of the planned model. As stereoEEG becomes more common in the presurgical evaluation of epilepsy, these tools will become increasingly important to facilitate targeted cortical resections.
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.|b Epilepsy Society, MRI Unit , Chalfont St Peter , UK.
authors.forename: Mark
authors.initials: M
authors.lastname: Nowell
authors.affiliation: c Centre of Medical Imaging and Computing , UCL , London , UK.
authors.forename: Rachel
authors.initials: R
authors.lastname: Sparks
authors.affiliation: d Department of Neurosurgery , National Hospital for Neurology and Neurosurgery , London , UK.
authors.forename: Gergely
authors.initials: G
authors.lastname: Zombori
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.|b Epilepsy Society, MRI Unit , Chalfont St Peter , UK.|d Department of Neurosurgery , National Hospital for Neurology and Neurosurgery , London , UK.
authors.forename: Anna
authors.initials: A
authors.lastname: Miserocchi
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.|b Epilepsy Society, MRI Unit , Chalfont St Peter , UK.
authors.forename: Roman
authors.initials: R
authors.lastname: Rodionov
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.|b Epilepsy Society, MRI Unit , Chalfont St Peter , UK.
authors.forename: Beate
authors.initials: B
authors.lastname: Diehl
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.|b Epilepsy Society, MRI Unit , Chalfont St Peter , UK.
authors.forename: Tim
authors.initials: T
authors.lastname: Wehner
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.
authors.forename: Mark
authors.initials: M
authors.lastname: White
authors.affiliation: c Centre of Medical Imaging and Computing , UCL , London , UK.
authors.forename: Sebastien
authors.initials: S
authors.lastname: Ourselin
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.|b Epilepsy Society, MRI Unit , Chalfont St Peter , UK.|d Department of Neurosurgery , National Hospital for Neurology and Neurosurgery , London , UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: McEvoy
authors.affiliation: a Department of Clinical and Experimental Epilepsy , UCL Institute of Neurology , London , UK.|b Epilepsy Society, MRI Unit , Chalfont St Peter , UK.
authors.forename: John
authors.initials: J
authors.lastname: Duncan
mesh_terms: D000328:Adult; D001921:Brain / Q000601:surgery; D001931:Brain Mapping / Q000379:methods; D000066491:Clinical Decision-Making / Q000379:methods; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D006801:Humans; D021621:Imaging, Three-Dimensional; D007430:Intraoperative Care / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods; D008297:Male; D064847:Multimodal Imaging / Q000379:methods; D038361:Neuronavigation / Q000379:methods*; D010347:Patient Care Planning; D010865:Pilot Projects
keywords: Image-guided surgery; functional neurosurgery; neuronavigation; operation