title: Autophagy Captures the Nobel Prize.
abstract: This year's Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi for the discovery of the molecular principles governing autophagy, an intracellular degradation pathway routed via lysosomes or vacuoles. It is a story of a simple yet insightful yeast genetic screen that revealed the inner circuitry of one of the most powerful quality-control pathways in cells.
authors.affiliation: The Francis Crick Institute, 1 Midland Road, NW1 1AT London, UK.
authors.forename: Sharon A
authors.initials: SA
authors.lastname: Tooze
authors.affiliation: Institute of Biochemistry II, School of Medicine, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences, Goethe University, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany. Electronic address: dikic@biochem2.uni-frankfurt.de.
authors.forename: Ivan
authors.initials: I
authors.lastname: Dikic
mesh_terms: D000818:Animals; D000071182:Autophagosomes / Q000502:physiology; D001343:Autophagy; D049673:History, 20th Century; D006801:Humans; D008247:Lysosomes / Q000502:physiology; D009613:Nobel Prize; D010827:Physiology / Q000266:history*; D015003:Yeasts / Q000166:cytology / Q000502:physiology