title: Gender- and Ethnicity-Related Differences in Optic Nerve Head Topography in Healthy Indian and Caucasian Participants.
abstract: We investigated the effect of ethnicity and gender on optic nerve head morphology in healthy subjects using spectral-domain optical coherence tomography (SD-OCT). Thirty-five Indian (i.e. Indian subcontinent) females, 34 Caucasian females, 32 Indian males, and 32 Caucasian males were examined using SD-OCT (Copernicus, Optopol Technology). Disc and rim areas were larger in Caucasian males compared with females but smaller in Indians males compared with females. Indian participants had significantly larger cup areas and volumes without significant differences in retinal nerve fibre layer (RNFL) thicknesses between groups. Gender and ethnicity differences should be considered in assessment of patients.
authors.affiliation: Ophthalmology Group, University of Leicester Leicester United Kingdom.
authors.forename: Anastasia V
authors.initials: AV
authors.lastname: Pilat
authors.affiliation: Ophthalmology Group, University of Leicester Leicester United Kingdom.
authors.forename: Irene
authors.initials: I
authors.lastname: Gottlob
authors.affiliation: Ophthalmology Group, University of Leicester Leicester United Kingdom.
authors.forename: Viral
authors.initials: V
authors.lastname: Sheth
authors.affiliation: Ophthalmology Group, University of Leicester Leicester United Kingdom.
authors.forename: Mervyn G
authors.initials: MG
authors.lastname: Thomas
authors.affiliation: Ophthalmology Group, University of Leicester Leicester United Kingdom.
authors.forename: Frank A
authors.initials: FA
authors.lastname: Proudlock
keywords: Gender and ethnicity; OCT; healthy optic nerve