title: Affinity of Mucormycosis for Basal Ganglia in Intravenous Drug Users: Case Illustration and Review of Literature.
abstract: Central nervous system mucormycosis is an aggressive fungal infection often ending in fatality. The usual circumstance is an immunocompromised individual presenting with rapidly progressive rhinocerebral involvement. An extremely rare variant of central nervous system mucormycosis isolated to the basal ganglia in an immunocompetent intravenous drug user is detailed in this manuscript. The patient was aggressively treated with aspiration of the fungal abscess and long-term intravenous antifungal agents.
authors.affiliation: Department of Neurosurgery, Upstate Medical University Hospital, Syracuse, New York, USA. Electronic address: hazamaa@upstate.edu.
authors.forename: Ali
authors.initials: A
authors.lastname: Hazama
authors.affiliation: Department of Neurosurgery, Upstate Medical University Hospital, Syracuse, New York, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Galgano
authors.affiliation: Department of Pathology, Upstate Medical University Hospital, Syracuse, New York, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Fullmer
authors.affiliation: Department of Neurosurgery, Upstate Medical University Hospital, Syracuse, New York, USA.
authors.forename: Walter
authors.initials: W
authors.lastname: Hall
authors.affiliation: Department of Neurosurgery, Upstate Medical University Hospital, Syracuse, New York, USA.
authors.forename: Lawrence
authors.initials: L
authors.lastname: Chin
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology*; D020314:Central Nervous System Fungal Infections / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D016867:Immunocompromised Host; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects*; D009682:Magnetic Resonance Spectroscopy; D019635:Neurosurgical Procedures / Q000379:methods; D011247:Pregnancy; D012233:Rhizopus / Q000472:pathogenicity; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents; D016756:Immunoglobulins, Intravenous
keywords: Cerebral fungal infection; Mucormycosis; Rhizopus