title: Design and implementation of a mobile system for lung cancer patient follow-up in China and initial report of the ongoing patient registry.
abstract: BACKGROUND
  Management of lung cancer remains a challenge. Although clinical and biological patient data are crucial for cancer research, these data may be missing from registries and clinical trials. Biobanks provide a source of high-quality biological material for clinical research; however, linking these samples to the corresponding patient and clinical data is technically challenging. We describe the mobile Lung Cancer Care system (mLCCare), a novel tool which integrates biological and clinical patient data into a single resource.
  
  
  METHODS
  mLCCare was developed as a mobile device application (app) and an internet website. Data storage is hosted on cloud servers, with the mobile app and website acting as a front-end to the system. mLCCare also facilitates communication with patients to remind them to take their medication and attend follow-up appointments.
  
  
  RESULTS
  Between January 2014 and October 2015, 5,080 patients with lung cancer have been registered with mLCCare. Data validation ensures all the patient information is of consistently high-quality. Patient cohorts can be constructed via user-specified criteria and data exported for statistical analysis by authorized investigators and collaborators. mLCCare forms the basis of establishing an ongoing lung cancer registry and could form the basis of a high-quality multisite patient registry. Integration of mLCCare with SMS messaging and WeChat functionality facilitates communication between physicians and patients.
  
  
  CONCLUSIONS
  It is hoped that mLCCare will prove to be a powerful and widely used tool that will enhance both research and clinical practice.
authors.affiliation: Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Xiangyun
authors.initials: X
authors.lastname: Ye
authors.affiliation: Research and Development Information China, AstraZeneca, Pudong, Shanghai, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Wei
authors.affiliation: Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Ziming
authors.initials: Z
authors.lastname: Li
authors.affiliation: Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Niu
authors.affiliation: Research and Development Information China, AstraZeneca, Pudong, Shanghai, China.
authors.forename: Jiemin
authors.initials: J
authors.lastname: Wang
authors.affiliation: Research and Development Information China, AstraZeneca, Pudong, Shanghai, China.
authors.forename: Yunqin
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Research and Development Information China, AstraZeneca, Pudong, Shanghai, China.
authors.forename: Zongming
authors.initials: Z
authors.lastname: Guo
authors.affiliation: Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Shun
authors.initials: S
authors.lastname: Lu
mesh_terms: D002681:China; D006801:Humans; D020407:Internet; D008175:Lung Neoplasms; D063731:Mobile Applications; D012042:Registries
keywords: China; data integration; lung cancer; mobile app; registry