title: How safe is minimally invasive pedicle screw placement for treatment of thoracolumbar spine fractures?
abstract: Prospective analysis of patients who underwent minimally invasive posterior instrumentation.
  
  
  
  The purpose of this study was to evaluate the safety of minimally invasive pedicle screw placement in patients with unstable thoracic and lumbar spine fractures using the conventional fluoroscopy technique. Although wound infection, haematoma, and new neurological deficit due to screw malplacement remain a common source of morbidity, estimates of their rates of occurrence remain relatively limited.
  
  
  
  2052 percutaneous pedicle screws in 433 consecutive patients were evaluated. The accuracy of pedicle screw placement was based on evaluation of axial 3-mm slice computed tomography scans. Morbidity and mortality data were collected prospectively.
  
  
  
  A total of 2029 of 2052 screws (99%) had a good or excellent position. 5 screws (0.2%) showed a higher grade violation of the medial pedicle wall. Seven patients (1.8%) needed revision due to screw malposition (3 pat.), surgical site infection, postoperative haematoma, implant failure (2 pat.), and technical difficulties.
  
  
  
  Minimally invasive transpedicular instrumentation is an accurate, reliable, and safe procedure to treat thoracic and lumbar spine fractures.
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany. heintel_t@ukw.de.
authors.forename: Timo Michael
authors.initials: TM
authors.lastname: Heintel
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Dannigkeit
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Annabel
authors.initials: A
authors.lastname: Fenwick
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Martin Cornelius
authors.initials: MC
authors.lastname: Jordan
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Jansen
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Fabian
authors.initials: F
authors.lastname: Gilbert
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Rainer
authors.initials: R
authors.lastname: Meffert
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000293:injuries / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D065289:Pedicle Screws / Q000009:adverse effects*; D011446:Prospective Studies; D016103:Spinal Fractures / Q000601:surgery*; D013123:Spinal Fusion / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D013904:Thoracic Vertebrae / Q000293:injuries / Q000601:surgery; D055815:Young Adult
keywords: Complications; Infection; Instrumentation; Minimally invasive; Thoracolumbar spine fractures