title: A practical synthesis of benzothiophenes via visible-light-promoted cyclization of disulfides and alkynes.
abstract: Visible-light-promoted intermolecular radical cyclization of disulfides and alkynes has been developed. Benzothiophenes bearing ester, ketone, aldehyde and aryl substituents were synthesized in good yields. The reaction was carried out in the absence of transition-metal catalysts and extra additives. Oxygen was used as the sole oxidant. In addition, the irradiation of sunlight could also promote the reaction efficiently.
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. yanming@mail.sysu.edu.cn.
authors.forename: Lin-Miao
authors.initials: LM
authors.lastname: Ye
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. yanming@mail.sysu.edu.cn.
authors.forename: Lu
authors.initials: L
authors.lastname: Qian
authors.affiliation: College of Pharmacy, Guilin Medical University, Guilin 541004, China.
authors.forename: Yan-Yan
authors.initials: YY
authors.lastname: Chen
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. yanming@mail.sysu.edu.cn.
authors.forename: Xue-Jing
authors.initials: XJ
authors.lastname: Zhang
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. yanming@mail.sysu.edu.cn.
authors.forename: Ming
authors.initials: M
authors.lastname: Yan