title: Role of MicroRNA in the Lung's Innate Immune Response.
abstract: The immune response to respiratory pathogens must be robust enough to defend the host yet properly constrained such that inflammation-induced tissue damage is avoided. MicroRNA (miRNA) are small noncoding RNA which posttranscriptionally influence gene expression. In this review, we discuss recent experimental evidence of the contribution of miRNA to the lung's response to bacterial and viral pathogens.
authors.affiliation: Department of Infectious Disease, Medimmune, Gaithersburg, MD, USA.
authors.forename: Taylor S
authors.initials: TS
authors.lastname: Cohen
mesh_terms: D000818:Animals; D001424:Bacterial Infections / Q000235:genetics / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate / Q000235:genetics; D008168:Lung / Q000276:immunology* / Q000382:microbiology / Q000821:virology; D008171:Lung Diseases / Q000235:genetics / Q000276:immunology*; D035683:MicroRNAs / Q000235:genetics*; D014777:Virus Diseases / Q000235:genetics / Q000276:immunology*
chemical_list: D035683:MicroRNAs
keywords: Immune response; MicroRNA; Respiratory host defense