title: Invasive Fungal Sinusitis Involving the Orbital Apex in a Patient with Chronic Renal Failure.
abstract: An 82-year-old man with chronic renal failure presented with invasive fungal sinusitis involving the right orbital apex. Intravenous liposomal amphotericin B was immediately administered with an intravenous sodium supplement. Subsequently, endoscopic sinus surgery was performed.Aspergillus fumigatuswas detected in nasal discharge culture on day 12. Because the patient's renal function had deteriorated by this time, therapy was changed to nasal inhalation of amphotericin B, which was discontinued after 1 month, and oral administration of voriconazole, which was discontinued after 2 months. During 6-month follow-up, the patient did not show recurrence of sinusitis or further decrease in renal function.
authors.affiliation: Department of Ophthalmology, ; Department of Ophthalmology, University of Seonam College of Medicine, Presbyterian Medical Center, Jeonju, Korea.
authors.forename: Hyera
authors.initials: H
authors.lastname: Kang
authors.affiliation: Department of Ophthalmology.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takahashi
authors.affiliation: Department of Otorhinolaryngology , and.
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Nishimura
authors.affiliation: Department of Infection Control and Prevention, Aichi Medical University , Aichi, Japan , and.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Yamagishi
authors.affiliation: Department of Infection Control and Prevention, Aichi Medical University , Aichi, Japan , and.
authors.forename: Hiroshige
authors.initials: H
authors.lastname: Mikamo
authors.affiliation: Department of Ophthalmology.
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Kakizaki
keywords: Liposomal amphotericin B; chronic renal failure; invasive fungal sinusitis; oral voriconazole; orbital apex