title: Can the lower urinary tract storage symptoms be completely resolved after plasmakinetic enucleation of the prostate?
abstract: The aim of this study was to determine whether the lower urinary tract storage symptoms of benign prostatic obstruction (BPO) could be completely resolved after plasmakinetic enucleation of the prostate (PKEP) and the possible predictors of persistent symptoms. Two hundred and sixty-seven cases of BPO performed PKEP from July 2008 to June 2009 were retrospectively analyzed. Five-year postoperative data were collected and compared with the preoperative data. According to the urodynamic results, the patients were divided into involuntary detrusor contraction (IDC) group (n = 95) and no IDC group (n = 172) preoperatively; the patients with IDC were divided into IDC-persistent group (n = 33) and IDC-resolved group (n = 62) after PKEP. The predictors of persistent IDC were analyzed. Compared with the preoperative data, the 5-year postoperative data showed that the IDC rate was lower (P = 0.000), Overactive Bladder Symptom Score (OABSS) was lower (P = 0.000), maximum cystometric capacity (MCC) was larger (P = 0.000), Prostate volume (PV) was smaller (P = 0.000), and prostate-specific antigen (PSA) was lower (P = 0.000). Compared with the no IDC group, the IDC group showed that the age was older (P = 0.016), MCC was smaller (P = 0.004), PSA was higher (P = 0.016), and Chronic Inflammation rate was higher (P = 0.004). Compared with IDC-resolved group after PKEP, IDC-persistent group showed that the age was older (P = 0.019), MCC was smaller (P = 0.000), PSA was higher (P = 0.013), and Chronic Inflammation rate was higher (P = 0.032). The present study shows that the storage symptoms are still needed to be focused on after PKEP. The advanced patient age, MCC, PSA, and chronic inflammation may be the important clinical predictors of persistent IDC.
authors.affiliation: Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
authors.forename: Bing-Kun
authors.initials: BK
authors.lastname: Li
authors.affiliation: Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
authors.forename: Bin-Shen
authors.initials: BS
authors.lastname: Chen
authors.affiliation: Department of Urology, The People's Hospital of Jiangmen, Jiangmen 529020, China.
authors.forename: Yu-Hong
authors.initials: YH
authors.lastname: Xin
authors.affiliation: Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
authors.forename: Chun-Xiao
authors.initials: CX
authors.lastname: Liu
authors.affiliation: Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
authors.forename: Shao-Bo
authors.initials: SB
authors.lastname: Zheng
authors.affiliation: Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
authors.forename: Ya-Wen
authors.initials: YW
authors.lastname: Xu
authors.affiliation: Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
authors.forename: Hu-Lin
authors.initials: HL
authors.lastname: Li
authors.affiliation: Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zou
authors.affiliation: Department of Urology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Li
mesh_terms: D000368:Aged; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000503:physiopathology / Q000601:surgery*; D011470:Prostatic Hyperplasia / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D011788:Quality of Life; D020728:Transurethral Resection of Prostate / Q000379:methods*; D016896:Treatment Outcome; D014563:Urodynamics / Q000502:physiology