title: The importance of evidence-based supportive care practice guidelines in childhood cancer-a plea for their development and implementation.
abstract: As cure rates in pediatric oncology have improved substantially over the last decades, supportive care has become increasingly important to reduce morbidity and mortality and improve quality of life in children with cancer. Currently, large variations exist in pediatric oncology supportive care practice, which might negatively influence care. This plea underlines the importance of development and implementation of trustworthy supportive care clinical practice guidelines, which we believe is the essential next step towards better supportive care practice, and thus a higher quality of care. To facilitate international development and endorsement, the International Pediatric Oncology Guidelines in Supportive Care Network has been established.
authors.affiliation: Department of Pediatric Oncology/Hematology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700, RB, Groningen, the Netherlands.
authors.forename: E A H
authors.initials: EAH
authors.lastname: Loeffen
authors.affiliation: Department of Pediatric Oncology, Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands.
authors.forename: L C M
authors.initials: LCM
authors.lastname: Kremer
authors.affiliation: Department of Pediatric Oncology, Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands.
authors.forename: R L
authors.initials: RL
authors.lastname: Mulder
authors.affiliation: Department of Pediatric Oncology, Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Font-Gonzalez
authors.affiliation: Department of Pharmacy and Research Institute, The Hospital for Sick Children, Toronto, Canada.|Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
authors.forename: L L
authors.initials: LL
authors.lastname: Dupuis
authors.affiliation: Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada.
authors.forename: L
authors.initials: L
authors.lastname: Sung
authors.affiliation: Pediatric Oncology Group of Ontario, Toronto, Canada.
authors.forename: P D
authors.initials: PD
authors.lastname: Robinson
authors.affiliation: Department of Pediatric Oncology, Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands.
authors.forename: M D
authors.initials: MD
authors.lastname: van de Wetering
authors.affiliation: Department of Pediatric Oncology/Hematology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700, RB, Groningen, the Netherlands. w.j.e.tissing@umcg.nl.
authors.forename: W J E
authors.initials: WJE
authors.lastname: Tissing
mesh_terms: D002648:Child; D055317:Evidence-Based Practice; D006801:Humans; D008495:Medical Oncology / Q000592:standards*; D009369:Neoplasms / Q000628:therapy*; D010166:Palliative Care / Q000379:methods / Q000592:standards*; D010372:Pediatrics / Q000592:standards*; D017410:Practice Guidelines as Topic; D011788:Quality of Life
keywords: Childhood cancer; Clinical practice guidelines; Evidence-based medicine; Supportive care