title: Analysis of the First 1000 Liver Transplants in Virgen del Rocío Hospital.
abstract: The goal of this work has been to analyze the first 1000 liver transplantations (LTs) performed in the Virgen del Rocío Hospital of Seville and to evaluate the changes in that time. We included 916 patients who had 1000 LTs. We distinguish 2 stages in the follow-up: the first stage, between 1990 and 2002, and the second, from 2003 to 2013 (Model for End-stage Liver Disease [MELD] stage). We analyzed recipient features, LT indications, donation criteria, surgical technique, complications, and survival both for patients and grafts. The median age of recipients was 53.50 ± 46.49 years old, with a noticeable increase after 2000. There were 3 times as many men as women. The most frequent indications for LT were hepatocellular disease (48.8%), followed by hepatocarcinoma (17.8%), retransplantation (8.1%), and cholestatic diseases (3.6%). Donors of Andalusian centers accounted for 88.2% of LTs, and 8.3% of LTs presented some arterial or venous complication. Biliary complications occurred in 15.6%. Patient survival at 1, 5, and 10 years was 77%, 63.5%, and 51.3%, respectively. In conclusion, some of the factors that negatively influenced survival of the patient were stage of the LT, hepatitis C virus-positive recipient, emergency cases, hepatocarcinoma, high consumption of blood products, and second transplantations.
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain. Electronic address: tinoko243@hotmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Tinoco-González
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Suárez-Artacho
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Bernal-Bellido
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Cepeda-Franco
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Ramallo-Solis
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Marín-Gómez
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Álamo-Martínez
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Serrano-Díez-Canedo
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Padillo-Ruíz
authors.affiliation: University Hospital Virgen del Rocío, Liver Transplant Unit, Seville, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Gómez-Bravo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery; D058625:End Stage Liver Disease / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D012086:Reoperation; D012189:Retrospective Studies; D013030:Spain; D016896:Treatment Outcome; D055815:Young Adult