title: Seco-pregnane glycosides from the stems of Epigynum auritum.
abstract: Chemical investigation of the stems of Epigynum auritum led to the isolation and identification of a novel 16,17-seco pregnane glycoside, epigynoside D, along with other three known compounds (2-4). The structure of compound 1 was elucidated by means of spectroscopic analysis, including HRESIMS, 1D and 2D NMR experiments. All isolated compounds were tested for their in vitro cytotoxic, immunological and anti-acetylcholinesterase activities.
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Fei
authors.initials: F
authors.lastname: Gao
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Yuan-Cheng
authors.initials: YC
authors.lastname: Yao
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Zong
authors.initials: Z
authors.lastname: Wan
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Sheng-Bao
authors.initials: SB
authors.lastname: Cai
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Jian
authors.initials: J
authors.lastname: Fan
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Tian-Rui
authors.initials: TR
authors.lastname: Zhao
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Jian-Xin
authors.initials: JX
authors.lastname: Cao
authors.affiliation: a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
authors.forename: Gui-Guang
authors.initials: GG
authors.lastname: Cheng
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D018547:Plant Stems / Q000737:chemistry; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D006027:Glycosides; D011278:Pregnanes; C574437:pregnane glycoside
keywords: Epigynum auritum; epigynoside D; pregnane glycoside