title: Access to functionalized thienopyridines via a reagent-capsule-assisted coupling, thiolation and cyclization cascade sequence.
abstract: Thienopyridines and related heterocycles were prepared in a straightforward manner in moderate to good yields and under mild conditions by palladium-catalysed cross-coupling of ortho-fluorinated iodopyridines and terminal alkynes, followed by a reagent-capsule-assisted thiolation cyclization process. By applying paraffin wax capsules to prevent catalyst poisoning and undesired side reactions, the separation and purification processes were reduced.
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Jialing
authors.initials: J
authors.lastname: Cai
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Shuo
authors.initials: S
authors.lastname: Huang
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Ruenfa
authors.initials: R
authors.lastname: He
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Lu
authors.initials: L
authors.lastname: Chen
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Donghan
authors.initials: D
authors.lastname: Chen
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Shaohua
authors.initials: S
authors.lastname: Jiang
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.affiliation: School of Chemical & Environmental Engineering, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com andonlee@163.com.
authors.forename: Yibiao
authors.initials: Y
authors.lastname: Li