title: Neurobiochemical and psychological factors influencing the eating behaviors and attitudes in anorexia nervosa.
abstract: The aim of this study was to determine the characteristic features which contribute to inappropriate eating attitudes in people suffering from anorexia nervosa, based on an analysis of recent data. Factors influencing these attitudes have a genetic, neurobiological, biochemical, affective-motivational, cognitive, and behavioral background. Another important issue addressed in the paper is a description of the mechanism leading to continuous dietary restrictions. The altered activity of neurotransmitters modulating patients' moods after the consumption of food and a disturbed responsiveness to enterohormones enhance affective-motivational and cognitive aspects which, in turn, impede the improvement of eating behaviors. An understanding of the mechanisms behind the factors affecting the maintenance of inappropriate eating attitudes may contribute to greater effectiveness in the treatment of anorexia nervosa.
authors.affiliation: Division of Biology of Civilization-Linked Diseases, Department of Chemistry and Clinical Biochemistry, Poznan University of Medical Sciences, Swiecickiego Str. 6, 60-781, Poznan, Poland. tgrzelak@ump.edu.pl.
authors.forename: Teresa
authors.initials: T
authors.lastname: Grzelak
authors.affiliation: Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Agata
authors.initials: A
authors.lastname: Dutkiewicz
authors.affiliation: Department of Biomaterials and Experimental Dentistry, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Paszynska
authors.affiliation: Psychiatric Genetics Unit, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Monika
authors.initials: M
authors.lastname: Dmitrzak-Weglarz
authors.affiliation: Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Slopien
authors.affiliation: Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Marta
authors.initials: M
authors.lastname: Tyszkiewicz-Nwafor
mesh_terms: D000818:Animals; D000856:Anorexia Nervosa / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy; D001294:Attitude to Health; D060825:Cognitive Dysfunction / Q000209:etiology / Q000523:psychology / Q000628:therapy; D003131:Combined Modality Therapy; D005247:Feeding Behavior / Q000523:psychology; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008960:Models, Psychological; D009042:Motivation; D009424:Nervous System Physiological Phenomena; D009771:Obsessive-Compulsive Disorder / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D057285:Precision Medicine
keywords: Anorexia nervosa; Eating disorders; Nutritional attitudes; Nutritional behaviors