title: Antioxidant and Antiproliferative Activities of Purslane Seed Oil.
abstract: The aim of this study was to evaluate the antioxidant and antiproliferative activities of PSOin vitroand its application in horse oil storage. We determined the reducing power of PSO and its scavenging effects on hydroxyl (•OH) and 1,1-diphenyl-2-picrylhydrazyl radicals (DPPH•) and tested its stabilizing effects on horse oil storage. The results showed that PSO had remarkable, dose-dependent antioxidant activities, and it effectively prevented horse oil lipid oxidation. We treated cervical cancer HeLa cells, esophageal cancer Eca-109 cells and breast cancer MCF-7 cells with PSO using non-neoplastic monkey kidney Vero cells as controls. The results indicate that PSO significantly inhibited tumor cell growth in a time- and dose-dependent fashion. Our studies suggest that PSO may be used as a substitute for synthetic antioxidants in food preservation and may be potentially useful as a food and cosmetic ingredient. Meanwhile, the oxidative stress can cause hypertension, so PSO is expected to develop a health care products for the prevention and mitigation hypertensive symptoms.
authors.affiliation: College of Life Sciences and Technology, Xinjiang University, Shengli Road 14, Urumqi, Xinjiang 830046, China.
authors.forename: Gai
authors.initials: G
authors.lastname: Guo
authors.affiliation: College of Life Sciences and Technology, Xinjiang University, Shengli Road 14, Urumqi, Xinjiang 830046, China.
authors.forename: Li
authors.initials: L
authors.lastname: Yue
authors.affiliation: College of Life Sciences and Technology, Xinjiang University, Shengli Road 14, Urumqi, Xinjiang 830046, China.
authors.forename: Shaoli
authors.initials: S
authors.lastname: Fan
authors.affiliation: College of Life Sciences and Technology, Xinjiang University, Shengli Road 14, Urumqi, Xinjiang 830046, China.
authors.forename: Siqun
authors.initials: S
authors.lastname: Jing
authors.affiliation: Department of Pharmaceutical Sciences, UNT System College of Pharmacy, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA.
authors.forename: Liang-Jun
authors.initials: LJ
authors.lastname: Yan
keywords: Anti-proliferation; Antioxidant; Portulaca oleracea L. seed oil (PSO); Storage application