title: Association of Serum Omentin-1 Concentrations with the Presence of Atrial Fibrillation.
abstract: BACKGROUND Omentin-1 is one of the adipokines associated with obesity, diabetes, and coronary heart disease development. We determined to investigate whether serum omentin-1 concentrations were correlated with the presence of atrial fibrillation (AF). MATERIAL AND METHODS Serum omentin-1 concentrations were examined in a cross-sectional population that included 220 patients with AF (70 with paroxysmal AF, 78 with persistent AF, and 72 with permanent AF) and 115 healthy controls. RESULTS Reduced serum omentin-1 concentrations were found in AF patients compared to the controls. In addition, patients with permanent AF had lower serum omentin-1 concentrations compared to patients with persistent AF and patients with paroxysmal AF. Significantly decreased serum omentin-1 concentrations were observed in persistent AF patients compared to paroxysmal AF patients. Spearman correlation analysis suggested that serum omentin-1 concentrations were negatively correlated with left atrial diameter in AF patients. CONCLUSIONS Serum omentin-1 concentrations were correlated with the presence of AF and atrial remolding.
authors.affiliation: Southern Medical University, Guangzhou, Guangdong, China (mainland).|Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Sha
authors.initials: S
authors.lastname: Tao
authors.affiliation: Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Yu-Qing
authors.initials: YQ
authors.lastname: Huang
authors.affiliation: Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: An-Ping
authors.initials: AP
authors.lastname: Cai
authors.affiliation: Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Cheng
authors.initials: C
authors.lastname: Huang
authors.affiliation: Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Community Health Services Center of Liaobu Town, Dongguan, Guangdong, China (mainland).
authors.forename: Song-Tao
authors.initials: ST
authors.lastname: Tang
authors.affiliation: Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Xue-Ju
authors.initials: XJ
authors.lastname: Yu
authors.affiliation: Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Dan
authors.initials: D
authors.lastname: Zhou
authors.affiliation: Southern Medical University, Guangzhou, Guangdong, China (mainland).|Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Ning
authors.initials: N
authors.lastname: Tan
authors.affiliation: Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China (mainland).
authors.forename: Ying-Qing
authors.initials: YQ
authors.lastname: Feng
mesh_terms: D054392:Adipokines / Q000378:metabolism; D000328:Adult; D000368:Aged; D001281:Atrial Fibrillation / Q000097:blood* / Q000503:physiopathology; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D016207:Cytokines / Q000097:blood*; D018450:Disease Progression; D005260:Female; D058851:GPI-Linked Proteins / Q000097:blood; D006325:Heart Atria / Q000503:physiopathology; D006801:Humans; D037102:Lectins / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D054392:Adipokines; D015415:Biomarkers; D016207:Cytokines; D058851:GPI-Linked Proteins; C432397:ITLN1 protein, human; D037102:Lectins