title: Pedicle screw fixation with kyphoplasty decreases the fracture risk of the treated and adjacent non-treated vertebral bodies: a finite element analysis.
abstract: Adjacent vertebral fractures are common in patients with osteoporotic vertebral compression fractures (OVCFs) after kyphoplasty. This finite element study was to examine whether short segment pedicle screw fixation (PSF) with kyphoplasty may decrease the fracture risk of the treated and adjacent non-treated vertebrae after kyphoplasty for OVCFs. By simulating cement augmentation with or without short segment pedicle screw fixation (PSF), two tridimensional, anatomically detailed finite element models of the T10-L2 functional spinal junction were developed. The insertion of pedicle screws into the intact vertebra apparently decreased the stress distribution of the treated vertebra in vertical compression and other load situations. The stress distribution in the bone structures of the intact vertebra adjacent to the intact-screwed vertebra was much less than that in the one adjacent to the treated vertebra. The insertion of pedicle screws into the intact vertebra greatly decreased the maximum displacement of the cortical bones and cancellous bones of the vertebrae. Our results indicated that short segment PSF with kyphoplasty may decrease the fracture risk of the treated and adjacent non-treated vertebrae in the management of OVCFs.
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China.|Department of Orthopedics, Chongqing Traditional Chinese Medicine Hospital (the First People's Hospital of Chongqing), Chongqing, 400011, China.
authors.forename: Pan
authors.initials: P
authors.lastname: Yang
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China.
authors.forename: Huan-Wen
authors.initials: HW
authors.lastname: Ding
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China. gzyyp@qq.com.
authors.forename: Jian
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
authors.forename: Lin-Qiang
authors.initials: LQ
authors.lastname: Ye
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Xiao
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Tu
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.affiliation: Orthopedic Hospital, Guangzhou General Hospital of People's Liberation Army, Guangzhou, 510010, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.affiliation: Department of Anatomy, Southwest Medical University, Luzhou, 646000, China.
authors.forename: Guo-Gang
authors.initials: GG
authors.lastname: Sun
mesh_terms: D003198:Computer Simulation; D020342:Finite Element Analysis; D005593:Fracture Fixation, Internal / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D058498:Kyphoplasty / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D058866:Osteoporotic Fractures / Q000209:etiology* / Q000517:prevention & control; D065289:Pedicle Screws / Q000009:adverse effects*; D011183:Postoperative Complications / Q000517:prevention & control; D016103:Spinal Fractures / Q000209:etiology* / Q000517:prevention & control; D013131:Spine / Q000000981:diagnostic imaging / Q000601:surgery*
keywords: biomechanics; finite element analysis; kyphoplasty; osteoporotic vertebral compression fractures; pedicle screw fixation