title: Effects of Perfluorooctane sulfonate on immobilization, heartbeat, reproductive and biochemical performance of Daphnia magna.
abstract: In recent years, Perfluorooctane sulfonate (PFOS) was widely detected in Yellow-Bohai Sea and other areas, causing a series of adverse effects in aquatic organisms. However, present studies of its chronic and acute toxicity on aquatic organisms were far more inadequate. Therefore, in the present study, Daphnia magna was used to investigate PFOS toxicity on their immobilization, heartbeat, reproductive and biochemical performance in acute, subchronic and chronic exposure. The results showed that the 48h-EC50value for immobilization was 79.35 mg L-1and the toxicity was classified as intermediate. Heartbeat was significantly stimulated and reproductive parameters were significantly suppressed by PFOS, which can be used to reflect the toxicological effects on individuals. On the other hand, intrinsic rate of natural increase was more sensitive than reproductive parameters, which indicated negative responses on population dynamics of Daphnia magna. In addition, there were different degrees of inhibition on GST, CAT and ChE activity, which indicated three types of enzyme could become biomarkers to chronic PFOS exposure. Most of selected and evaluated endpoints have significant sensitivity to PFOS at the concentration of 8 mg L-1during subchronic and chronic exposure.
authors.affiliation: State Key Laboratory of Urban and Regional Ecology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Ruoyu
authors.initials: R
authors.lastname: Liang
authors.affiliation: College of Resources and Environmental Sciences, China Agriculture University, Beijing, 100193, China.
authors.forename: Jiao
authors.initials: J
authors.lastname: He
authors.affiliation: State Key Laboratory of Urban and Regional Ecology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China. Electronic address: yajuanshi@rcees.ac.cn.
authors.forename: Yajuan
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Shandong Xiehe University, Shandong, 250107, China.
authors.forename: Zhifen
authors.initials: Z
authors.lastname: Li
authors.affiliation: State Key Laboratory of Urban and Regional Ecology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; SCOPE (Scientific Committee on Problems of the Environment) Beijing Office, Beijing, 100085, China.
authors.forename: Suriyanarayanan
authors.initials: S
authors.lastname: Sarvajayakesavalu
authors.affiliation: State Key Laboratory of Urban and Regional Ecology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Yvette
authors.initials: Y
authors.lastname: Baninla
authors.affiliation: Beijing Sustainable Green Energy ET. Co., Ltd, 100192, China.
authors.forename: Feifan
authors.initials: F
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Urban and Regional Ecology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Chen
authors.affiliation: School of Environment & Natural Resources, Renmin University of China, Beijing, 100059, China.
authors.forename: Xiangbo
authors.initials: X
authors.lastname: Xu
authors.affiliation: State Key Laboratory of Urban and Regional Ecology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Yonglong
authors.initials: Y
authors.lastname: Lu
mesh_terms: D017738:Alkanesulfonic Acids / Q000633:toxicity*; D000818:Animals; D003621:Daphnia / Q000187:drug effects* / Q000502:physiology; D005466:Fluorocarbons / Q000633:toxicity*; D006321:Heart / Q000187:drug effects / Q000502:physiology; D008297:Male; D012098:Reproduction / Q000187:drug effects; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D017738:Alkanesulfonic Acids; D005466:Fluorocarbons; D014874:Water Pollutants, Chemical; C076994:perfluorooctane sulfonic acid
keywords: Daphnia magna; Enzyme activity; Heartbeat; PFOS; Reproduction