title: Current practice in continuous renal replacement therapy: An epidemiological multicenter study.
abstract: OBJECTIVE
  The aim of the study is to ascertain the most relevant aspects of the current management of renal replacement therapy (RRT) in critically ill patients, and to analyze renal function recovery and mortality in patients undergoing RRT.
  
  
  METHODS
  A non-interventional three-month observational study was made in 2012, with a follow-up period of 90 days, in 21 centers in Catalonia (Spain). Demographic information, severity scores and clinical data were obtained, as well as RRT parameters.
  
  
  METHODS
  patients aged ≥ 16 years admitted to Intensive Care Units (ICUs) and subjected to RRT.
  
  
  RESULTS
  A total of 261 critically ill patients were recruited, of which 35% had renal dysfunction prior to admission. The main reason for starting RRT was oliguria; the most widely used RRT modality was hemodiafiltration; and the median prescribed dose at baseline was 35mL/kg/h. The median time of RRT onset from ICU admission was one day. The mortality rate at 30 and 90 days was 46% and 54%, respectively, and was associated to greater severity scores and a later onset of RRT. At discharge, 85% of the survivors had recovered renal function.
  
  
  CONCLUSIONS
  Current practice in RRT in Catalonia abides with the current clinical practice guidelines. Mortality related to RRT is associated to later onset of such therapy. The renal function recovery rate at hospital discharge was 85% among the patients subjected to RRT.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Germans Trias i Pujol , España. Electronic address: teresatomasa@gmail.com.
authors.forename: T M
authors.initials: TM
authors.lastname: Tomasa Irriguible
authors.affiliation: Servicio de Medicina Intensiva, Hospital de Bellvitge, L'Hospitalet de Llobregat (Barcelona), España.
authors.forename: J
authors.initials: J
authors.lastname: Sabater Riera
authors.affiliation: Servicio de Nefrología, Hospital Clinic, Barcelona, España.
authors.forename: E
authors.initials: E
authors.lastname: Poch López de Briñas
authors.affiliation: Servicio de Nefrología, Hospital Vall d'Hebron, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Fort Ros
authors.affiliation: Servicio de Nefrología, Fundació Puigvert, Barcelona, España.
authors.forename: M J
authors.initials: MJ
authors.lastname: Lloret Cora
authors.affiliation: Departamento de Epidemiología, Área de Medicina Preventiva y Salud Pública, Universidad Autónoma de Barcelona, Hospital Germans Trias i Pujol, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Roca Antònio
authors.affiliation: Servicio de Medicina Intensiva, Hospital Parc Taulí de Sabadell, Sabadell (Barcelona), España.
authors.forename: A
authors.initials: A
authors.lastname: Navas Pérez
authors.affiliation: Servicio de Medicina Intensiva, Hospital Josep Trueta de Girona, Gerona, España.
authors.forename: P
authors.initials: P
authors.lastname: Ortiz Ballujera
authors.affiliation: Servicio de Medicina Intensiva, Hospital Arnau de Vilanova, Lérida, España.
authors.forename: L
authors.initials: L
authors.lastname: Servià Goixart
authors.affiliation: Servicio de Medicina Intensiva, Hospital Mútua de Terrassa, Tarrasa (Barcelona), España.
authors.forename: F J
authors.initials: FJ
authors.lastname: González de Molina Ortiz
authors.affiliation: Servicio de Medicina Intensiva, Hospital Joan XXIII, Tarragona, España.
authors.forename: C
authors.initials: C
authors.lastname: Rovira Anglès
authors.affiliation: Servicio de Medicina Intensiva, Hospital Moisés Broggi, Sant Joan Despí, Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Rodríguez López
authors.affiliation: Servicio de Medicina Intensiva, Hospital Sant Pau, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Roglan Piqueras
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003422:Critical Care / Q000379:methods / Q000592:standards; D016638:Critical Illness; D005260:Female; D019983:Guideline Adherence; D017583:Hemodiafiltration / Q000379:methods / Q000592:standards / Q000706:statistics & numerical data; D017052:Hospital Mortality; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009846:Oliguria / Q000453:epidemiology / Q000628:therapy; D017410:Practice Guidelines as Topic; D020127:Recovery of Function; D017582:Renal Replacement Therapy / Q000379:methods / Q000592:standards / Q000706:statistics & numerical data*; D013030:Spain / Q000453:epidemiology; D055815:Young Adult
keywords: Acute kidney injury; Critically ill patients; Lesión renal aguda; Paciente crítico; Prognosis; Pronóstico; Recuperación de la función renal; Renal function recovery; Renal replacement therapy; Terapias de reemplazo renal