title: Prognostic significance of hepatic arterial collaterals in liver transplant recipients with biliary strictures.
abstract: The aim of this study was to determine the prevalence of hepatic artery stenosis (HAS) and the prognostic implications of hepatic arterial collaterals in liver transplant (LT) recipients with biliary strictures.
  
  
  
  The 105 LT recipients transplanted between 2004 and 2015 at our center had documented biliary strictures. HAS and collaterals were assessed in high-quality imaging of the hepatic artery available from 66 recipients. Clinical, demographic, and biochemical recipient and donor data were retrospectively analyzed and tested for their association with biliary or arterial complications after LT.
  
  
  
  The prevalence of HAS was 68% (45 of 66) in LT recipients with biliary strictures. Seventy-six percent (37 of 49) of patients with nonanastomotic biliary strictures had HAS. This was significantly higher than in patients with anastomotic stricture, where 47% (8 of 17) of patients had a pathological hepatic arteriogram (P=.039). The location of bile duct strictures was not predictive for outcome. In contrast, arterial collaterals were associated with significantly better patient and graft survival.
  
  
  
  Impaired hepatic arterial perfusion is frequently associated with nonanastomotic strictures, but less closely correlated with anastomotic strictures. On survival analysis, hepatic arterial collaterals have a protective effect.
authors.affiliation: Department of Medicine, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: André
authors.initials: A
authors.lastname: Viveiros
authors.affiliation: Department of Radiology, Medical University and University Hospital of Innsbruck & Tirol Kliniken GmbH, Innsbruck, Austria.
authors.forename: Rafael
authors.initials: R
authors.lastname: Rehwald
authors.affiliation: Department of Radiology, Medical University and University Hospital of Innsbruck & Tirol Kliniken GmbH, Innsbruck, Austria.
authors.forename: Erich
authors.initials: E
authors.lastname: Vettori
authors.affiliation: Department of Medicine, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: Armin
authors.initials: A
authors.lastname: Finkenstedt
authors.affiliation: Department of Medicine, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: Maria
authors.initials: M
authors.lastname: Effenberger
authors.affiliation: Department of Medicine, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: Benedikt
authors.initials: B
authors.lastname: Schaefer
authors.affiliation: Department of Medicine, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: Livia
authors.initials: L
authors.lastname: Dorn
authors.affiliation: Department of Medicine, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: Herbert
authors.initials: H
authors.lastname: Tilg
authors.affiliation: Department of Visceral-, Transplant- And Thoracic Surgery, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: Stefan
authors.initials: S
authors.lastname: Schneeberger
authors.affiliation: Department of Radiology, Medical University and University Hospital of Innsbruck & Tirol Kliniken GmbH, Innsbruck, Austria.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Glodny
authors.affiliation: Department of Medicine, Medical University and University Hospital of Innsbruck, Innsbruck, Austria.
authors.forename: Heinz
authors.initials: H
authors.lastname: Zoller
authors.affiliation: Department of Radiology, Medical University and University Hospital of Innsbruck & Tirol Kliniken GmbH, Innsbruck, Austria.
authors.forename: Martin C
authors.initials: MC
authors.lastname: Freund
mesh_terms: D000368:Aged; D001660:Biliary Tract Diseases / Q000503:physiopathology / Q000628:therapy*; D003251:Constriction, Pathologic / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006499:Hepatic Artery / Q000601:surgery*; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011379:Prognosis; D012189:Retrospective Studies
keywords: angiography; biliary pathology after liver transplantation; collaterals; hepatic arterial complications liver transplantation biliary; stenosis