title: Effects of Anti-CD206 Antibodies on Macrophage Functions in Male CBF1 Mice with Lipidemia.
abstract: The effects of anti-CD208 antibodies (mannose receptor) on functional characteristics of peritoneal macrophages were studied in intact mice and mice with lipidemia induced by poloxamer-407. Lipidemia was associated with suppression of phagocytosis and increase in spontaneous proliferative potential and NO production by macrophages. Anti-CD206 antibodies suppressed NO production by macrophages in mice with lipidemia.
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia. aplykov2@mail.ru.
authors.forename: A P
authors.initials: AP
authors.lastname: Lykov
authors.affiliation: Research Institute of Physiology and Fundamental Medicine, Novosibirsk, Russia.
authors.forename: T A
authors.initials: TA
authors.lastname: Korolenko
authors.affiliation: Institute of Fundamental and Clinical Immunology, Novosibirsk, Russia.
authors.forename: L V
authors.initials: LV
authors.lastname: Sakhno
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Poveshchenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Bondarenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Surovtseva
authors.affiliation: Research Institute of Physiology and Fundamental Medicine, Novosibirsk, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Goncharova
mesh_terms: D000818:Animals; D000906:Antibodies / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects; D004912:Erythrocytes / Q000276:immunology; D015870:Gene Expression; D006949:Hyperlipidemias / Q000139:chemically induced / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D037181:Lectins, C-Type / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000276:immunology; D008070:Lipopolysaccharides / Q000494:pharmacology; D017737:Macrophages, Peritoneal / Q000187:drug effects* / Q000276:immunology / Q000473:pathology; D008297:Male; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000276:immunology; D051379:Mice; D009569:Nitric Oxide / Q000096:biosynthesis; D010587:Phagocytosis / Q000187:drug effects*; D020442:Poloxamer; D061251:Primary Cell Culture; D017382:Reactive Oxygen Species / Q000276:immunology / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000276:immunology; D012756:Sheep
chemical_list: D000906:Antibodies; D037181:Lectins, C-Type; D008070:Lipopolysaccharides; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins; D017382:Reactive Oxygen Species; D011956:Receptors, Cell Surface; D020442:Poloxamer; D009569:Nitric Oxide
keywords: P-407; lipidemia; macrophages; phagocytosis; reactive oxygen species