title: Spectrum and Clinical Course of Visual Field Abnormalities in Ethambutol Toxicity.
abstract: Visual toxicities from ethambutol are rare but represent one of the few causes of non-glaucomatous and non-compressive bitemporal hemianopsia. The authors present a six-patient case series illustrating variable clinical presentation and reversibility of visual loss in patients treated with ethambutol forMycobacterium aviumcomplex, including four patients who presented with visual field defects suggestive of bitemporal hemianopsia. Two additional patients were being followed for glaucoma, developed visual field defects with ethambutol treatment, and subsequently recovered with cessation of drug. In patients being treated with ethambutol, reversible bitemporal hemianopsia was the most commonly noted presentation of ethambutol toxicity.
authors.affiliation: Department of Surgery, University of Virginia , Charlottesville, Virginia, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Mendel
authors.affiliation: Department of Ophthalmology, University of North Carolina , Chapel Hill, North Carolina, USA.
authors.forename: David
authors.initials: D
authors.lastname: Fleischman
authors.affiliation: Department of Ophthalmology, Duke University , Durham, North Carolina, USA.
authors.forename: R Rand
authors.initials: RR
authors.lastname: Allingham
authors.affiliation: Department of Ophthalmology, Duke University , Durham, North Carolina, USA.
authors.forename: Henry
authors.initials: H
authors.lastname: Tseng
authors.affiliation: Department of Ophthalmology, University of North Carolina , Chapel Hill, North Carolina, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Chesnutt
keywords: Bitemporal; Mycobacterium; ethambutol; hemianopsia; toxicity