title: Clinical Outcome after Endovascular Sealing of Abdominal Aortic Aneurysms: A Retrospective Cohort Study.
abstract: BACKGROUND
  The aim of this study is to present the clinical outcome of endovascular aneurysm sealing (EVAS) with the Nellix endoprosthesis in patients with abdominal aortic aneurysms treated in our institution.
  
  
  METHODS
  This is a retrospective, single center, observational cohort study. A departmental database was interrogated to extract demographics, clinical information, and outcome of all patients treated with EVAS between December 2013 and December 2015. Outcome measures included technical success (successful device deployment and absence of any endoleak at completion angiography), mortality, major complications, incidence of endoleaks, aneurysm rupture, and reintervention.
  
  
  RESULTS
  Sixty-five patients (49 men) with a mean (standard deviation) age of 78 (6.9) years were successfully treated with EVAS, with no 30-day mortality. The cohort included 1 patient with ruptured aneurysm, 9 patients with late complications of previous aortoiliac repairs (2 open, 7 endovascular), and 4 patients who required a total of 9 visceral chimneys for juxtarenal aneurysms. Six patients (9%) suffered major postoperative complications and 4 (6%) required intervention. There were no early or late endoleaks or aneurysm ruptures. After a median (range) follow-up of 12 (0-24) months, there was no aneurysm-related mortality; 2 patients (3%) required late aneurysm-related interventions.
  
  
  CONCLUSIONS
  EVAS can be performed with good outcomes up to 2 years postoperatively. Longer follow-up on larger cohorts is needed to prove the efficacy of this technique.
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Maria
authors.initials: M
authors.lastname: Karouki
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Charles
authors.initials: C
authors.lastname: Swaelens
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Luigi
authors.initials: L
authors.lastname: Iazzolino
authors.affiliation: Department of Radiology, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Richard G
authors.initials: RG
authors.lastname: McWilliams
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Robert K
authors.initials: RK
authors.lastname: Fisher
authors.affiliation: Department of Radiography, University of Salford, Salford, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: England
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK. Electronic address: f.torella@liverpool.ac.uk.
authors.forename: Francesco
authors.initials: F
authors.lastname: Torella
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D000072226:Computed Tomography Angiography; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D004739:England; D006801:Humans; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000628:therapy; D011474:Prosthesis Design; D019233:Retreatment; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome