title: Can the Drosophila model help in paving the way for translational medicine in heart failure?
abstract: Chronic heart failure is a common consequence of various heart diseases. Mechanical force is known to play a key role in heart failure development through regulating cardiomyocyte hypertrophy. In order to understand the complex disease mechanism, this article discussed a multi-disciplinary approach that may aid the illustration of heart failure molecular process.
authors.affiliation: Bournemouth University, Bournemouth, U.K.
authors.forename: Lisha
authors.initials: L
authors.lastname: Ma
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism; D004195:Disease Models, Animal; D029721:Drosophila Proteins / Q000378:metabolism; D004331:Drosophila melanogaster / Q000378:metabolism*; D006333:Heart Failure / Q000378:metabolism*; D006801:Humans; D008955:Models, Cardiovascular; D057170:Translational Research, Biomedical / Q000379:methods*
chemical_list: D029721:Drosophila Proteins; D000255:Adenosine Triphosphate; D002118:Calcium
keywords: Drosophila melanogaster; heart failure; integrins; mechanical forces; mechanotransduction