title: Perspectives of immunotherapy in hepatocellular carcinoma (HCC).
abstract: Immunotherapy is considered a new treatment option for many tumor entities, as decades of research into cancer immunotherapy have recently yielded promising results. Indeed, impressive clinical results of checkpoint blockade inhibitors in malignant melanoma and non-small cell lung cancer indicate the therapeutic potential of tumor-specific immune restoration. Over the years, different immunotherapeutic approaches have been evaluated for the treatment of hepatocellular carcinoma (HCC) with some respectable results. In this review article, we will summarize the key studies of the past 30 years and will elucidate in which direction the dynamic field of HCC immunotherapy is currently moving.
authors.forename: N
authors.initials: N
authors.lastname: Büttner
authors.forename: N
authors.initials: N
authors.lastname: Schmidt
authors.forename: R
authors.initials: R
authors.lastname: Thimme
mesh_terms: D019496:Cancer Vaccines / Q000276:immunology / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000276:immunology / Q000628:therapy*; D019317:Evidence-Based Medicine; D006801:Humans; D007167:Immunotherapy; D016219:Immunotherapy, Adoptive / Q000639:trends*; D008113:Liver Neoplasms / Q000276:immunology / Q000628:therapy*; D050130:Oncolytic Virotherapy / Q000639:trends*; D016896:Treatment Outcome
chemical_list: D019496:Cancer Vaccines