title: A Review on Microfluidic Paper-Based Analytical Devices for Glucose Detection.
abstract: Glucose, as an essential substance directly involved in metabolic processes, is closely related to the occurrence of various diseases such as glucose metabolism disorders and islet cell carcinoma. Therefore, it is crucial to develop sensitive, accurate, rapid, and cost effective methods for frequent and convenient detections of glucose. Microfluidic Paper-based Analytical Devices (μPADs) not only satisfying the above requirements but also occupying the advantages of portability and minimal sample consumption, have exhibited great potential in the field of glucose detection. This article reviews and summarizes the most recent improvements in glucose detection in two aspects of colorimetric and electrochemical μPADs. The progressive techniques for fabricating channels on μPADs are also emphasized in this article. With the growth of diabetes and other glucose indication diseases in the underdeveloped and developing countries, low-cost and reliably commercial μPADs for glucose detection will be in unprecedentedly demand.
authors.affiliation: Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China. spliu613@sjtu.edu.cn.
authors.forename: Shuopeng
authors.initials: S
authors.lastname: Liu
authors.affiliation: Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China. suwenqiong@sjtu.edu.cn.
authors.forename: Wenqiong
authors.initials: W
authors.lastname: Su
authors.affiliation: Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China. dingxianting@sjtu.edu.cn.
authors.forename: Xianting
authors.initials: X
authors.lastname: Ding
mesh_terms: D003124:Colorimetry; D004563:Electrochemistry; D005947:Glucose / Q000032:analysis*; D056656:Lab-On-A-Chip Devices; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D010209:Paper
chemical_list: D005947:Glucose
keywords: colorimetric detection; electrochemical detection; glucose; microfluidic paper-based analytical devices (μPAD)