title: Bilateral Optic Disc Swelling Following Anastrozole Therapy.
abstract: A 56-year-old female with early-stage breast cancer, stage IA grade 1 endometrial cancer, and stage IC grade 1 ovarian cancer developed sudden-onset visual changes and right inferior visual field defect following anastrozole therapy. Examination revealed severe bilateral optic disc swelling and impaired visual acuity. Laboratory work-up was otherwise unremarkable. Anastrozole was discontinued and over the next month, patient had near-complete resolution of swelling in the right eye and improvement in the left eye. This is the only reported case of optic disc swelling following anastrozole therapy.
authors.affiliation: Pritzker School of Medicine.
authors.forename: Oscar Jim Michael
authors.initials: OJ
authors.lastname: Coppes
authors.affiliation: Department of Neurology.
authors.forename: Rimas V
authors.initials: RV
authors.lastname: Lukas
authors.affiliation: Section of Hematology and Oncology.
authors.forename: Gini F
authors.initials: GF
authors.lastname: Fleming
authors.affiliation: Section of Ophthalmology.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Nichols
authors.affiliation: Department of Obstetrics and Gynecology, University of Chicago Chicago, Illinois USA.
authors.forename: Meaghan
authors.initials: M
authors.lastname: Tenney
authors.affiliation: Department of Neurology.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Bernard
keywords: Breast neoplasms; chemotherapy; optical coherence tomography; papilloedema; vision