title: Acute Ischemic Stroke and Acute on Chronic Kidney Disease.
abstract: Ischemic stroke is due to either local thrombus formation or emboli that occlude a cerebral artery, together with chronic kidney disease represent major mortality and morbidity.Here we present a case of 53 years old Malay man, admitted to a hospital in Malaysia complaining of sudden on set of weakness on right sided upper and lower limb associated with slurred speech. Patient was also suffering from uncontrolled hypertension, hyperlipidemia, chronic kidney disease stage 4, and diabetes mellitus (uncontrolled). He was diagnosed with acute ischemic stroke with cranial nerve 7 palsy (with right hemiparesis), acute on chronic kidney disease precipitated by dehydration and ACE inhibitor, and hyperkalemia. Patients with ischemic disease and chronic kidney disaese require constant monitering and careful selected pharmacotherapy. Patient was placed under observation and was prescribed multiple pharamacotherpay to stabalise detoriating condition.
authors.affiliation: Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Malaysia.
authors.forename: R A
authors.initials: RA
authors.lastname: Aftab
authors.affiliation: Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Malaysia.
authors.forename: A H
authors.initials: AH
authors.lastname: Khan
authors.affiliation: Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Malaysia.
authors.forename: H A
authors.initials: HA
authors.lastname: AbdulRazzaq
authors.affiliation: Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Malaysia.
authors.forename: A S
authors.initials: AS
authors.lastname: Adnan
mesh_terms: D000208:Acute Disease; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects; D020330:Bell Palsy / Q000175:diagnosis; D002545:Brain Ischemia / Q000175:diagnosis; D003681:Dehydration / Q000150:complications; D003920:Diabetes Mellitus / Q000175:diagnosis; D006801:Humans; D006947:Hyperkalemia / Q000150:complications; D006973:Hypertension / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis* / Q000209:etiology; D020521:Stroke / Q000175:diagnosis*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors
keywords: ischemic disease; chronic kidney disease; uncontrolled hypertension.