title: Evaluation of the Effects of Cypermethrin on Female Reproductive Function by Using Rabbit Model and of the Protective Role of Chinese Propolis.
abstract: The prophylactic effects of Chinese propolis against cypermethrin toxicity were evaluated by performing ovary and uterus histopathology, as well as by characterizing ovarian function, embryos, and litters. Cypermethrin induced atypia in the ovary and uterus, and decreased the ovulation sites and the number of embryos. Cypermethrin-induced oxidative stress during pregnancy, decreased the parturition rate as well as the number and weight of offspring and increased the incidence of morphological malformations in the offspring. Administration of propolis to cypermethrin-treated animals mitigated cypermethrin-induced reproductive toxicity.
authors.affiliation: Department of Home Economics Department, Faculty of Specific Education, Alexandria University, Alexandria 21545, Egypt.
authors.forename: A E
authors.initials: AE
authors.lastname: Khatab
authors.affiliation: Department of Animal Production, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria 21545, Egypt.
authors.forename: N M
authors.initials: NM
authors.lastname: Hashem
authors.affiliation: Department of Home Economics, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria 21545, Egypt.
authors.forename: L M
authors.initials: LM
authors.lastname: El-Kodary
authors.affiliation: Department of Home Economics Department, Faculty of Specific Education, Alexandria University, Alexandria 21545, Egypt.
authors.forename: F M
authors.initials: FM
authors.lastname: Lotfy
authors.affiliation: Department of Animal Production, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria 21545, Egypt.
authors.forename: G A
authors.initials: GA
authors.lastname: Hassan
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D005260:Female; D007306:Insecticides / Q000633:toxicity*; D023421:Models, Animal; D010053:Ovary / Q000187:drug effects* / Q000502:physiology; D011429:Propolis / Q000737:chemistry / Q000494:pharmacology*; D011722:Pyrethrins / Q000633:toxicity*; D011817:Rabbits; D014599:Uterus / Q000187:drug effects* / Q000502:physiology
chemical_list: D000975:Antioxidants; D007306:Insecticides; D011722:Pyrethrins; C017160:cypermethrin; D011429:Propolis