title: Permanent Bilateral Vision Loss in Eclamptic Posterior Reversible Encephalopathy Syndrome.
abstract: Posterior reversible encephalopathy syndrome (PRES) classically consists of reversible vasogenic oedema in the posterior circulation territories, which is reversible both clinically and radiologically in the majority of patients after the control of hypertension. The authors describe a 27-year-old eclamptic patient with PRES in accelerated hypertension who revealed permanent vision loss associated with bilateral Purtscher retinopathy. One of the two competing theories that explain vasogenic brain oedema in PRES is excessive autoregulation leading to the dilation of cerebral arterial vessels, particularly in the occipito-parietal vasculatures. Dysfunction of endothelial cells that results in constriction of vessels has also been hypothesised as a cause of PRES. The concurrence of bilateral vaso-occlusive retinopathy and PRES supports the hypothesis that vasoconstriction is a more plausible mechanism of vasogenic oedema in PRES.
authors.affiliation: Department of Neurology, Chonbuk National University School of Medicine , Jeonju, Korea.
authors.forename: Ki-Youn
authors.initials: KY
authors.lastname: So
authors.affiliation: Department of Neurology, Chonbuk National University School of Medicine, Jeonju, Korea, ; Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea, and.
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Oh
authors.affiliation: Graduate School of Flexible and Printable Electronics, Chonbuk National University , Jeonju, Korea.
authors.forename: Si-Young
authors.initials: SY
authors.lastname: Yang
keywords: Eclampsia; Purtscher retinopathy; posterior reversible encephalopathy syndrome (PRES); vision loss