title: Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy.
abstract: Ocular neuromyotonia (ONM) is a neuro-ophthalmic disorder characterized by episodic diplopia caused by contraction of one or more ocular muscles due to spontaneous excitation of the respective ocular motor nerve. We report a patient whose ocular neuromyotonia arose in the setting of a subacute demyelinating polyneuropathy consistent with chronic inflammatory demyelinating polyneuropathy (CIDP) and subsequently resolved following the initiation of intravenous immunoglobulin (IVIg) for her neuropathy. Our patient provides additional evidence towards the role of demyelination and ephaptic neurotransmission in ocular neuromyotonia and also represents the first reported case of ocular neuromyotonia associated with a systemic neurological condition.
authors.affiliation: Department of Neurology, Washington University in St. Louis , St. Louis, Missouri, USA.
authors.forename: Nathan H
authors.initials: NH
authors.lastname: Kung
authors.affiliation: Department of Neurology, Washington University in St. Louis , St. Louis, Missouri, USA.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Bucelli
authors.affiliation: Department of Ophthalmology and Visual Sciences, Washington University in St. Louis , St. Louis, Missouri, USA.
authors.forename: Collin M
authors.initials: CM
authors.lastname: McClelland
authors.affiliation: Department of Ophthalmology and Visual Sciences, Washington University in St. Louis , St. Louis, Missouri, USA.
authors.forename: Gregory P
authors.initials: GP
authors.lastname: Van Stavern
keywords: Chronic inflammatory demyelinating polyneuropathy; diplopia; ocular motility; ocular neuromyotonia