title: Invasive Lobular Carcinoma of the Breast: Appearance on Digital Breast Tomosynthesis.
abstract: BACKGROUND
  The aim of this study was to characterize the signs of invasive lobular carcinoma of the breast on digital breast tomosynthesis (DBT) imaging.
  
  
  METHODS
  The study group included 23 women with pathologically proven invasive lobular carcinoma of the breast for whom both digital mammography (DM) and DBT images were available. The images were read jointly by 2 experienced breast radiologists. Findings were recorded according to the descriptors in the Breast Imaging and Reporting Data System lexicon and correlated with the detailed pathology results.
  
  
  RESULTS
  In 21 of the 23 patients, the combination of DM and DBT yielded pathologic findings (91%). Architectural distortions or spiculations were demonstrated in 87% of cases. The addition of DBT to DM improved lesion detection by more clearly depicting both the lesion margins and architectural distortions. Only 2 lesions were occult by both DM and DBT, including 1 lesion in a peripheral location that was not incorporated in the standard mediolateral oblique and craniocaudal views.
  
  
  CONCLUSIONS
  DBT improves the detection of invasive lobular carcinoma lesions by more clearly depicting architectural distortions and spiculations.
authors.affiliation: Department of Radiology, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Petah Tikva, Israel.
authors.forename: Ahuva
authors.initials: A
authors.lastname: Grubstein
authors.affiliation: Department of Radiology, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Petah Tikva, Israel.
authors.forename: Yael
authors.initials: Y
authors.lastname: Rapson
authors.affiliation: Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Petah Tikva, Israel; Department of Pathology, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel, Petah Tikva, Israel.
authors.forename: Sara
authors.initials: S
authors.lastname: Morgenstern
authors.affiliation: Department of Radiology, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Petah Tikva, Israel.
authors.forename: Itai
authors.initials: I
authors.lastname: Gadiel
authors.affiliation: Department of Radiology, Carmel Medical Center, Haifa, Israel, Petah Tikva, Israel.
authors.forename: Amit
authors.initials: A
authors.lastname: Haboosheh
authors.affiliation: Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Petah Tikva, Israel; Davidoff Center, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.
authors.forename: Rinat
authors.initials: R
authors.lastname: Yerushalmi
authors.affiliation: Department of Radiology, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Petah Tikva, Israel.
authors.forename: Maya
authors.initials: M
authors.lastname: Cohen
keywords: Lobular carcinoma; Tomosynthesis