title: Increased Prevalence of Optic Disc Drusen after Papilloedema from Idiopathic Intracranial Hypertension: On the Possible Formation of Optic Disc Drusen.
abstract: This is a 25-year observational retrospective review of 372 consecutive participants with optic disc drusen or resolved papilloedema from idiopathic intracranial hypertension. The prevalence of optic disc drusen at 19% among eyes with resolved papilloedema was approximately 10 times higher and significantly increased (p< 0.001) as compared with the occurrence in the general population. Eyes with both resolved papilloedema and optic disc drusen had similar visual acuity and visual field outcome as compared with resolved papilloedema alone. Eyes with exposed drusen had significantly worse visual acuity and visual field outcome (p< 0.001) than buried drusen. The high prevalence of optic disc drusen after papilloedema has resolved suggests a non-coincidental relationship. Optic disc drusen formation can be a sequela of papilloedema.
authors.affiliation: Neuro-Ophthalmology Unit, Department of Ophthalmology, Alpert Medical School of Brown University/Lifespan/Rhode Island Hospital , Providence, Rhode Island, USA.
authors.forename: Faith A
authors.initials: FA
authors.lastname: Birnbaum
authors.affiliation: Neuro-Ophthalmology Unit, Mason Eye Institute, University of Missouri , Columbia, Missouri, USA.
authors.forename: Gabriella M
authors.initials: GM
authors.lastname: Johnson
authors.affiliation: Neuro-Ophthalmology Unit, Department of Ophthalmology, Alpert Medical School of Brown University/Lifespan/Rhode Island Hospital , Providence, Rhode Island, USA.
authors.forename: Lenworth N
authors.initials: LN
authors.lastname: Johnson
authors.affiliation: Neuro-Ophthalmology Unit, Mason Eye Institute, University of Missouri , Columbia, Missouri, USA.
authors.forename: Bokkwan
authors.initials: B
authors.lastname: Jun
authors.affiliation: Lifespan Biostatistics Core, Departments of Orthopaedics and Surgery, Alpert Medical School of Brown University/Lifespan/Rhode Island Hospital , Providence, Rhode Island, USA.
authors.forename: Jason T
authors.initials: JT
authors.lastname: Machan
keywords: Idiopathic intracranial hypertension; optic disc drusen; papilloedema; pseudopapilloedema; pseudotumor cerebri