title: Effective Neurally Adjusted Ventilatory Assist (NAVA) Ventilation in a Child With Jeune Syndrome.
abstract: Jeune syndrome (asphyxiating thoracic dystrophy) is a rare skeletal dysplasia mainly characterized by dystrophy of the thoracic cage. Neurally adjusted ventilatory assist (NAVA) is a respiratory support in which pressure assistance is provided in proportion to and synchronous with the electrical activity of the diaphragm. We present the case of a 4-month-old infant with asphyxiating thoracic dystrophy and respiratory failure successfully ventilated with NAVA. In this case, NAVA improved patient-ventilator synchrony, reducing endotracheal secretion and gastric overdistention. The reduction of breathing effort and the improvement in enteral feeding tolerance and weight gain made the patient eligible for thoracic surgical correction.
authors.affiliation: Neonatal and Pediatric ICU, Maggiore della Carità Hospital, Novara, Italy; and.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Cosi
authors.affiliation: Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy. genonigiulia@gmail.com.
authors.forename: Giulia
authors.initials: G
authors.lastname: Genoni
authors.affiliation: Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
authors.forename: Alice
authors.initials: A
authors.lastname: Monzani
authors.affiliation: Neonatal and Pediatric ICU, Maggiore della Carità Hospital, Novara, Italy; and.
authors.forename: Barbara
authors.initials: B
authors.lastname: Pilan
authors.affiliation: Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Lavrano
authors.affiliation: Neonatal and Pediatric ICU, Maggiore della Carità Hospital, Novara, Italy; and.
authors.forename: Federica
authors.initials: F
authors.lastname: Ferrero
mesh_terms: D004613:Ellis-Van Creveld Syndrome / Q000628:therapy*; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D007223:Infant; D059725:Interactive Ventilatory Support; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy; D015430:Weight Gain