title: The Colloid Controversy: Are Colloids Bad and What Are the Options?
abstract: Biologic and synthetic colloid solutions are frequently used to increase oncotic pressure and to treat shock. Research has shown that each product has both risks and benefits. Hydroxyethyl starches have gained a reputation for increasing risk of death, acute kidney injury, and coagulation abnormalities in people, but additional studies are needed to see whether these concerns hold true in veterinary patients. This article reviews the risks and benefits of currently available products.
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, The University of Georgia, 2200 College Station Road, Athens, GA 30602, USA.
authors.forename: Christine
authors.initials: C
authors.lastname: Wong
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, The University of Georgia, 2200 College Station Road, Athens, GA 30602, USA. Electronic address: akoenig@uga.edu.
authors.forename: Amie
authors.initials: A
authors.lastname: Koenig
mesh_terms: D000418:Albumins / Q000627:therapeutic use; D000818:Animals; D002371:Cat Diseases / Q000628:therapy*; D002415:Cats; D003102:Colloids / Q000627:therapeutic use*; D003911:Dextrans / Q000627:therapeutic use; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs; D005440:Fluid Therapy / Q000379:methods / Q000662:veterinary*; D006801:Humans; D010949:Plasma; D016032:Randomized Controlled Trials as Topic
chemical_list: D000418:Albumins; D003102:Colloids; D003911:Dextrans
keywords: Albumin; Blood products; Colloid therapy; Colloids; Endothelial glycocalyx; Human serum albumin; Hydroxyethyl starch; Plasma