title: Salivary Diagnostics Using Purified Nucleic Acids.
abstract: Saliva is an easily accessible fluid that has led to increasing interest in the development of salivary diagnostics. This chapter describes some of the newer tools and procedures for collection, stabilization, and storage of oral fluid matrices that aid in the successful use of saliva as a test specimen. This chapter focuses particularly on nucleic acid components for downstream molecular diagnostic (MDx) testing, since this is probably the area where saliva is likely to have the greatest impact in improving healthcare for the general population.
authors.affiliation: Oasis Diagnostics® Corporation, 15720 NE 31st Avenue, Vancouver, WA, 98686, USA. PDS@4saliva.com.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Slowey
mesh_terms: D015415:Biomarkers; D002458:Cell Fractionation / Q000379:methods; D004247:DNA / Q000302:isolation & purification; D055354:Exosomes; D006801:Humans; D000073890:Liquid Biopsy; D025202:Molecular Diagnostic Techniques; D009696:Nucleic Acids / Q000302:isolation & purification; D012313:RNA / Q000302:isolation & purification; D012463:Saliva / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D009696:Nucleic Acids; D012313:RNA; D004247:DNA
keywords: DNA; Exosomes; Nucleic acids; RNA; Saliva; Stabilization