title: Mouthpiece ventilation and complementary techniques in patients with neuromuscular disease: A brief clinical review and update.
abstract: Noninvasive ventilatory support (NVS) is sometimes reported as suboptimal in patients with neuromuscular disease (NMD). The reasons for this include inadequate ventilator settings and/or lack of interface tolerance. NVS has been used for many years in patients with NMD disorders as a viable alternative to continuous ventilatory support via a tracheostomy tube. The mouthpiece ventilation (MPV) is a ventilatory mode that is used as daytime ventilatory support in combination with other ventilatory modalities and interfaces for nocturnal NVS. However, there is still a poor understanding of this method's benefits compared with other modalities. This review aims to highlight the indications and advantages along with the disadvantages of MPV.
authors.affiliation: 1 Lung Function and Ventilation Unit, Department of Pulmonary Medicine, Porto, Portugal.
authors.forename: Tiago
authors.initials: T
authors.lastname: Pinto
authors.affiliation: 2 Clinical and Academic Department of Sleep and Breathing, Royal Brompton Hospital, London, UK.
authors.forename: Michelle
authors.initials: M
authors.lastname: Chatwin
authors.affiliation: 3 Don Gnocchi Foundation IRCSS, Milan, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Banfi
authors.affiliation: 4 Faculty of Medicine, University of Porto, Porto, Portugal.
authors.forename: Joao Carlos
authors.initials: JC
authors.lastname: Winck
authors.affiliation: 5 Respiratory Diseases Unit and ALS Centre, Hospital of Sestri Levante, Italy.
authors.forename: Antonello
authors.initials: A
authors.lastname: Nicolini
mesh_terms: D006801:Humans; D009468:Neuromuscular Diseases / Q000150:complications / Q000628:therapy*; D063087:Noninvasive Ventilation / Q000295:instrumentation* / Q000379:methods; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*
keywords: Neuromuscular disease; complementary techniques; daytime ventilatory support; mouthpiece ventilation; noninvasive ventilatory support