title: The Mediator of Hematopoietic Stem Cell Homeostasis.
abstract: Mechanisms establishing and maintaining promoter-enhancer interactions in hematopoietic stem cells (HSCs) to maintain stem cell identity are not fully understood. In this issue of Cell Stem Cell, Aranda-Orgilles et al. (2016) describe a role for a member of the Mediator complex in maintaining HSC-specific enhancers and hematopoietic homeostasis.
authors.affiliation: The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME 04609, USA.
authors.forename: Sneha
authors.initials: S
authors.lastname: Borikar
authors.affiliation: The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME 04609, USA. Electronic address: jennifer.trowbridge@jax.org.
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Trowbridge
mesh_terms: D006412:Hematopoietic Stem Cells; D006706:Homeostasis; D006801:Humans