title: Comparison of toxicity and outcome in advanced stage non-small cell lung cancer patients treated with intensity-modulated (chemo-)radiotherapy using IMRT or VMAT.
abstract: Retrospective evaluation of 188 advanced stage non-small cell lung cancer patients treated with IMRT or VMAT revealed a limited increase of moderate to severe acute esophageal toxicity after VMAT. Acute pulmonary toxicity and severe late toxicity were low. Overall survival did not differ between the IMRT and VMAT groups.
authors.affiliation: Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: robin.wijsman@radboudumc.nl.
authors.forename: Robin
authors.initials: R
authors.lastname: Wijsman
authors.affiliation: Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Frank
authors.initials: F
authors.lastname: Dankers
authors.affiliation: Institute of Radiooncology, Helmholtz-Zentrum Dresden-Rossendorf, Germany; Department of Radiation Oncology, University Hospital Carl Gustav Carus of the Technische Universität Dresden, Germany; OncoRay, National Center for Radiation Research in Oncology, Dresden, Germany; German Cancer Consortium (DKTK), Partnersite Dresden, Germany; National Center for Tumor Diseases, Partnersite Dresden, Germany.
authors.forename: Esther G C
authors.initials: EGC
authors.lastname: Troost
authors.affiliation: Institute of Radiooncology, Helmholtz-Zentrum Dresden-Rossendorf, Germany; Department of Radiation Oncology, University Hospital Carl Gustav Carus of the Technische Universität Dresden, Germany.
authors.forename: Aswin L
authors.initials: AL
authors.lastname: Hoffmann
authors.affiliation: Department of Pulmonary Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Erik H F M
authors.initials: EHFM
authors.lastname: van der Heijden
authors.affiliation: Department of Radiology, Leiden University Medical Center, The Netherlands; Biomedical Photonic Imaging Group, MIRA Institute, University of Twente, Enschede, The Netherlands; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Lioe-Fee
authors.initials: LF
authors.lastname: de Geus-Oei
authors.affiliation: Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Johan
authors.initials: J
authors.lastname: Bussink
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated / Q000009:adverse effects / Q000379:methods*; D012189:Retrospective Studies
keywords: Intensity-modulated radiation therapy; Non-small cell lung cancer; Toxicity; Volumetric-modulated radiation therapy