title: TheAGTGene M235T Polymorphism and Response of Power-Related Variables to Aerobic Training.
abstract: The C allele of the M235T (rs699) polymorphism of theAGTgene correlates with higher levels of angiotensin II and has been associated with power and strength sport performance. The aim of the study was to investigate whether or not selected power-related variables and their response to a 12-week program of aerobic dance training are modulated by theAGTM235T genotype in healthy participants. Two hundred and one Polish Caucasian women aged 21 ± 1 years met the inclusion criteria and were included in the study. All women completed a 12-week program of low and high impact aerobics. Wingate peak power and total work capacity, 5 m, 10 m, and 30 m running times and jump height and jump power were determined before and after the training programme. All power-related variables improved significantly in response to aerobic dance training. We found a significant association between the M235T polymorphism and jump-based variables (squat jump (SJ) height, p = 0.005; SJ power, p = 0.015; countermovement jump height, p = 0.025; average of 10 countermovement jumps with arm swing (ACMJ) height, p = 0.001; ACMJ power, p = 0.035). Specifically, greater improvements were observed in the C allele carriers in comparison with TT homozygotes. In conclusion, aerobic dance, one of the most commonly practiced adult fitness activities in the world, provides sufficient training stimuli for augmenting the explosive strength necessary to increase vertical jump performance. TheAGTgene M235T polymorphism seems to be not only a candidate gene variant for power/strength related phenotypes, but also a genetic marker for predicting response to training.
authors.affiliation: Gdansk University of Physical Education and Sport, Faculty of Tourism and Recreation , Gdansk, Poland.
authors.forename: Zarębska
authors.initials: Z
authors.lastname: Aleksandra
authors.affiliation: Gdansk University of Physical Education and Sport, Faculty of Tourism and Recreation , Gdansk, Poland.
authors.forename: Jastrzębski
authors.initials: J
authors.lastname: Zbigniew
authors.affiliation: Gdansk University of Physical Education and Sport, Faculty of Tourism and Recreation , Gdansk, Poland.
authors.forename: Moska
authors.initials: M
authors.lastname: Waldemar
authors.affiliation: University of Szczecin, Faculty of Physical Education and Health Promotion , Szczecin, Poland.
authors.forename: Leońska-Duniec
authors.initials: LD
authors.lastname: Agata
authors.affiliation: Gdansk University of Physical Education and Sport, Faculty of Tourism and Recreation , Gdansk, Poland.
authors.forename: Kaczmarczyk
authors.initials: K
authors.lastname: Mariusz
authors.affiliation: Gdansk University of Physical Education and Sport, Faculty of Tourism and Recreation, Gdansk, Poland; University of Szczecin, Faculty of Physical Education and Health Promotion, Szczecin, Poland.
authors.forename: Sawczuk
authors.initials: S
authors.lastname: Marek
authors.affiliation: Gdansk University of Physical Education and Sport, Faculty of Tourism and Recreation, Gdansk, Poland; University of Szczecin, Faculty of Physical Education and Health Promotion, Szczecin, Poland.
authors.forename: Maciejewska-Skrendo
authors.initials: MS
authors.lastname: Agnieszka
authors.affiliation: Institute of Sport , Warsaw, Poland.
authors.forename: Żmijewski
authors.initials: Ż
authors.lastname: Piotr
authors.affiliation: Academy of Physical Education in Katowice , Katowice, Poland.
authors.forename: Ficek
authors.initials: F
authors.lastname: Krzysztof
authors.affiliation: Pomeranian Medical University , Department of Oral Surgery, Szczecin, Poland.
authors.forename: Trybek
authors.initials: T
authors.lastname: Grzegorz
authors.affiliation: Gdansk University of Physical Education and Sport, Faculty of Tourism and Recreation , Gdansk, Poland.
authors.forename: Lulińska-Kuklik
authors.initials: LK
authors.lastname: Ewelina
authors.affiliation: Kazan Federal University , Kazan, Russia.
authors.forename: Ekaterina A
authors.initials: EA
authors.lastname: Semenova
authors.affiliation: Kazan State Medical University, Kazan, Russia; Federal Research Clinical Centre of Physical-Chemical Medicine, Moscow, Russia.
authors.forename: Ildus I
authors.initials: II
authors.lastname: Ahmetov
authors.affiliation: University of Szczecin, Faculty of Physical Education and Health Promotion , Szczecin, Poland.
authors.forename: Cięszczyk
authors.initials: C
authors.lastname: Paweł
keywords: Training adaptation; aerobic dance; genetic polymorphism; renin-angiotensin system