title: Negative perceptions of hepatitis B vaccination among attendees of an urban free testing center for sexually transmitted infections in France.
abstract: Official French health care policy recommends vaccinations against hepatitis B for all infants and at-risk adults. Attendees at our free testing center for sexually transmitted infections (FTC-STI) routinely express hepatitis B vaccine hesitancy. We aimed in this exposed population to explore the extent of knowledge concerning HBV infection, to quantify HBV vaccine refusal, and to identify the reasons for this refusal.
  
  
  
  During a 3-month period in 2013, all attendees at the Grenoble FTC-STI were given an anonymous questionnaire exploring their knowledge of hepatitis B, perception of the hepatitis B vaccine, acceptance of free same-day hepatitis B vaccination, and reasons for refusing this offer (where applicable).
  
  
  
  The questionnaire was completed by 735 attendees (64.7% of those attending during the study period)(59.9% men; age 27.9 ± 9.2). Most respondents identified hepatitis B as a potentially severe, potentially lifelong illness existing in France. Concerning the hepatitis B vaccine, less than 50% totally or mostly agreed that it is safe; when asked whether the vaccine is dangerous, 44.2% answered "I don't know" and 14.0% agreed; when asked whether the vaccine is "not well characterized," 45.0%, answered "I don't know" and 26.5% agreed. When asked whether they mistrust the hepatitis B vaccine or all vaccines in general, 39.0% and 28.9% of those unvaccinated agreed, respectively. Two thirds refused to get vaccinated on the same day. When asked whether they were afraid of the adverse effects of this vaccine, only 18.7% disagreed.
  
  
  
  Negative perceptions of the hepatitis B vaccine are widespread in this at-risk population. Consequently, a successful communication strategy must reassure this at-risk population of the vaccine's innocuous nature.
authors.affiliation: a Health Prospective and Education , Conseil Général de l'Isère , Grenoble , France.|b Free testing center for sexually transmitted infections (CEGIDD) , Conseil Général de l'Isère , Grenoble , France.
authors.forename: Lauranne
authors.initials: L
authors.lastname: Moyroud
authors.affiliation: a Health Prospective and Education , Conseil Général de l'Isère , Grenoble , France.
authors.forename: Sarah
authors.initials: S
authors.lastname: Hustache
authors.affiliation: a Health Prospective and Education , Conseil Général de l'Isère , Grenoble , France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Goirand
authors.affiliation: b Free testing center for sexually transmitted infections (CEGIDD) , Conseil Général de l'Isère , Grenoble , France.
authors.forename: Marianne
authors.initials: M
authors.lastname: Hauzanneau
authors.affiliation: b Free testing center for sexually transmitted infections (CEGIDD) , Conseil Général de l'Isère , Grenoble , France.|c Infectious Disease Unit , University Hospital , Grenoble , France.|d Team "HIV and other human persistent viruses ," Institut de Biologie Structurale, UMR 5075 UGA-CEA-CNRS , Grenoble , France.|e Fédération d'Infectiologie Multidisciplinaire de l'Arc Alpin , Université Grenoble Alpes , Grenoble , France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Epaulard
mesh_terms: D000328:Adult; D005260:Female; D005602:France / Q000453:epidemiology; D007722:Health Knowledge, Attitudes, Practice; D006509:Hepatitis B / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology; D017325:Hepatitis B Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008297:Male; D010342:Patient Acceptance of Health Care; D012749:Sexually Transmitted Diseases / Q000517:prevention & control; D011795:Surveys and Questionnaires; D019037:Urban Health Services; D014611:Vaccination / Q000523:psychology*
chemical_list: D017325:Hepatitis B Vaccines
keywords: hepatitis B; hesitancy; perceptions; sexually transmitted infection; side effects; vaccine