title: Early Response to treatment in Eating Disorders: A Systematic Review and a Diagnostic Test Accuracy Meta-Analysis.
abstract: Early response to eating disorders treatment is thought to predict a later favourable outcome. A systematic review of the literature and meta-analyses examined the robustness of this concept.
  
  
  
  The criteria used across studies to define early response were summarised following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Diagnostic Test Accuracy methodology was used to estimate the size of the effect.
  
  
  
  Findings from 24 studies were synthesized and data from 14 studies were included in the meta-analysis. In Anorexia Nervosa, the odds ratio of early response predicting remission was 4.85(95%CI: 2.94-8.01) and the summary Area Under the Curve (AUC) = .77. In Bulimia Nervosa, the odds ratio was 2.75(95%CI:1.24-6.09) and AUC = .67. For Binge Eating Disorder, the odds ratio was 5.01(95%CI: 3.38-7.42) and AUC = .71.
  
  
  
  Early behaviour change accurately predicts later symptom remission for Anorexia Nervosa and Binge Eating Disorder but there is less predictive accuracy for Bulimia Nervosa. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.
authors.affiliation: Department of Psychological Medicine, King's College London, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, UK.|Federal University of Rio de Janeiro, Institute of Psychiatry (IPUB-UFRJ), Brazil.
authors.forename: Bruno Palazzo
authors.initials: BP
authors.lastname: Nazar
authors.affiliation: Department of Psychological Medicine, King's College London, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, UK.
authors.forename: Louise Kathrine
authors.initials: LK
authors.lastname: Gregor
authors.affiliation: Department of Psychological Medicine, King's College London, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, UK.|University of Palermo, Department of Psychology and Educational Sciences, Palermo, Italy.
authors.forename: Gaia
authors.initials: G
authors.lastname: Albano
authors.affiliation: University of Palermo, Department of Psychology and Educational Sciences, Palermo, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Marchica
authors.affiliation: University of Palermo, Department of Psychology and Educational Sciences, Palermo, Italy.
authors.forename: Gianluca Lo
authors.initials: GL
authors.lastname: Coco
authors.forename: Valentina
authors.initials: V
authors.lastname: Cardi
authors.affiliation: Department of Psychological Medicine, King's College London, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), London, UK.
authors.forename: Janet
authors.initials: J
authors.lastname: Treasure
mesh_terms: D000856:Anorexia Nervosa / Q000175:diagnosis / Q000628:therapy; D056912:Binge-Eating Disorder / Q000175:diagnosis / Q000628:therapy; D052018:Bulimia Nervosa / Q000175:diagnosis / Q000628:therapy; D003955:Diagnostic Tests, Routine; D001068:Feeding and Eating Disorders / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D015203:Reproducibility of Results; D013997:Time Factors; D016896:Treatment Outcome
keywords: Anorexia Nervosa; Bulimia Nervosa; binge eating disorder; cognitive behavioural therapy; early response; eating disorders; family therapy