title: Wartime toxin exposure: recognising the silent killer.
abstract: Wartime toxin exposures have been implicated in the genesis of malignancy in war veterans. Agent Orange, one toxin among many, has been linked to malignancy and the subcomponent phenoxyacetic acid has been associated with soft tissue sarcomas (STSs). This case demonstrates the association between a wartime toxin exposure (Agent Orange) and subsequent cancer development. Ultimately, we aim to highlight the importance of simple, specific questions in the patient history to account for previous wartime toxin exposures.
authors.affiliation: Department of General Surgery, Sinai Hospital of Baltimore, Baltimore, Maryland, USA.
authors.forename: Kamran
authors.initials: K
authors.lastname: Khan
authors.affiliation: Department of General Surgery, Sinai Hospital of Baltimore, Baltimore, Maryland, USA.
authors.forename: Susan E
authors.initials: SE
authors.lastname: Wozniak
authors.affiliation: Department of Surgery, Sinai Center for Geriatric Surgery, Baltimore, Maryland, USA.
authors.forename: JoAnn
authors.initials: J
authors.lastname: Coleman
authors.affiliation: Department of Surgical Oncology, Alvin and Lois Cancer Institute, Sinai Hospital of Baltimore, Baltimore, Maryland, USA.
authors.forename: Mukund S
authors.initials: MS
authors.lastname: Didolkar
mesh_terms: D015085:2,4,5-Trichlorophenoxyacetic Acid / Q000506:poisoning*; D015084:2,4-Dichlorophenoxyacetic Acid / Q000506:poisoning*; D000279:Administration, Cutaneous; D000075182:Agent Orange; D002618:Chemical Warfare; D003678:Defoliants, Chemical / Q000506:poisoning*; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D000072317:Polychlorinated Dibenzodioxins / Q000506:poisoning*; D018570:Risk Assessment; D012509:Sarcoma / Q000139:chemically induced*; D014728:Veterans; D047829:Vietnam Conflict
chemical_list: D003678:Defoliants, Chemical; D000072317:Polychlorinated Dibenzodioxins; D015084:2,4-Dichlorophenoxyacetic Acid; D000075182:Agent Orange; D015085:2,4,5-Trichlorophenoxyacetic Acid