title: Intestinal Bacterial Infection Diagnosed by Histological Examination of Endoscopic Biopsy Specimens.
abstract: Intestinal spirochetosis (IS) in humans is characterized by spirochetal microorganisms attached to the luminal surface of the colonic epithelium. In the present case, attached organisms appeared as 3- to 4 μm-thick (average thickness, 3.4 μm) basophilic fringes or haze in HE-stained endoscopic biopsy specimens. The basophilic fringes were clearly labeled byTreponema pallidumantiserum. Because IS is relatively rare in developed countries, thin basophilic fringes characteristic of IS are readily overlooked. Thus, the recognition of histological characteristics of this disease is important for its diagnosis.
authors.affiliation: Department of Pathology II, Kansai Medical University, Hirakata, Japan.
authors.forename: Michiko
authors.initials: M
authors.lastname: Yuki
authors.affiliation: Department of Pathology II, Kansai Medical University, Hirakata, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Emoto
authors.affiliation: Department of Pathology II, Kansai Medical University, Hirakata, Japan.
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Yoshizawa
authors.affiliation: Department of Pathology II, Kansai Medical University, Hirakata, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Yuri
authors.affiliation: Department of Pathology II, Kansai Medical University, Hirakata, Japan.
authors.forename: Airo
authors.initials: A
authors.lastname: Tsubura
keywords: Bacteria; Biopsy; Immunohistochemistry; Intestinal infection