title: Neogenin regulates mitochondrial activity in pre-implantation mouse embryos.
abstract: • Mitochondrial activation signaling pathways are not clearly identified.
  • Embryonic mitochondria activity is important for a successful pregnancy and live birth.
  • Neogenin is a multi-functional receptor that contributes to embryo development.
  • Neogenin as a receptor is related to mitochondrial activation and replication.
  • Neogenin could activate mitochondria in pre-implantation embryo development.
authors.affiliation: CHA Fertility Center Seoul, Jung-gu, Seoul, 04637, Republic of Korea; Department of Animal Biotechnology, Bio-Organ Research Center/Animal Resources Research Center, Konkuk University, Seoul, 05029, Republic of Korea.
authors.forename: Kyoung Hee
authors.initials: KH
authors.lastname: Choi
authors.affiliation: Department of Animal Biotechnology, Sahmyook University, Seoul, 01795, Republic of Korea.
authors.forename: Seon Hwa
authors.initials: SH
authors.lastname: Hong
authors.affiliation: CHA Fertility Center Seoul, Jung-gu, Seoul, 04637, Republic of Korea.
authors.forename: Hye Ran
authors.initials: HR
authors.lastname: Lee
authors.affiliation: Department of Animal Biotechnology, Bio-Organ Research Center/Animal Resources Research Center, Konkuk University, Seoul, 05029, Republic of Korea. Electronic address: htl3675@konkuk.ac.kr.
authors.forename: Hoon Taek
authors.initials: HT
authors.lastname: Lee
authors.affiliation: CHA Fertility Center Seoul, Jung-gu, Seoul, 04637, Republic of Korea; Department of Biomedical Science, College of Life Science, CHA University, Pochen, Gyounggi-do, 11160 Republic of Korea. Electronic address: jaeho@cha.ac.kr.
authors.forename: Jae Ho
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Animal Biotechnology, Sahmyook University, Seoul, 01795, Republic of Korea. Electronic address: leesj@syu.ac.kr.
authors.forename: Sang Jin
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000378:metabolism*; D015536:Down-Regulation; D005260:Female; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008810:Mice, Inbred C57BL; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism; D008853:Microscopy; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism*; D011247:Pregnancy; D015854:Up-Regulation
chemical_list: D008565:Membrane Proteins; D035683:MicroRNAs; C091279:neogenin
keywords: Development; Mitochondria; Neogenin; Pre-implantation embryo