title: An unrecognised presentation of Takayasu arteritis: superficial femoral artery involvement.
abstract: OBJECTIVE
  Superficial femoral artery (SFA) involvement in Takayasu arteritis (TAK) has rarely been reported. The purpose of this study was to investigate the clinical characteristic and clinical outcomes of endovascular therapy in such patients.
  
  
  METHODS
  We analysed the data collected from 105 consecutive patients with TAK, who were diagnosed from January 2011 to December 2013. All patients underwent ankle brachial index (ABI) measurements and angiography. Nine patients with an ABI <0.9 and SFA stenosis (≥50%) were detected. Of them, 5 patients underwent percutaneous transluminal angioplasty (PTA) in SFA lesions. The clinical features, angiographic findings, treatment, and follow-up outcomes were investigated retrospectively.
  
  
  RESULTS
  Thirteen SFA stenosis in 8.6% patients (9/105) was found. The mean age was 44.3±15.7 years (all female) and mean Rutherford stage was 2.1±0.6. Compared with that at baseline, the ABI (0.98±0.03 vs. 0.66±0.09, p=0.001) and 6-min walking capacity (361±47 vs. 224±44 m, p<0.001) after PTA had improved significantly. During a mean follow-up of 27.4±10.6 months, the changes of ABI (0.29±0.06 vs. -0.04±-0.04, p<0.001) differed significantly between SFA lesions that had undergone PTA and those without PTA. Restenosis was found in one SFA lesion 23 months after PTA. No severe adverse events occurred in 5 patients who underwent PTA during the perioperative period and follow-up.
  
  
  CONCLUSIONS
  SFA involvement in TAK is not rare. PTA is a safe and feasible way to improve SFA ischaemia.
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Dong
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Wuqiang
authors.initials: W
authors.lastname: Che
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. jxj103@hotmail.com.
authors.forename: Xiongjing
authors.initials: X
authors.lastname: Jiang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Peng
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Yubao
authors.initials: Y
authors.lastname: Zou
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Huimin
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Yuejin
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Runlin
authors.initials: R
authors.lastname: Gao
mesh_terms: D000328:Adult; D000792:Angiography; D000800:Angioplasty, Balloon / Q000009:adverse effects; D055109:Ankle Brachial Index; D003251:Constriction, Pathologic; D017079:Exercise Tolerance; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D020127:Recovery of Function; D012008:Recurrence; D012039:Regional Blood Flow; D012189:Retrospective Studies; D013625:Takayasu Arteritis / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency; D000070857:Walk Test; D055815:Young Adult