title: Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone.
authors.affiliation: Department of Medicine, Division of Gastroenterology & Hepatology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania satish.rattan@jefferson.edu.
authors.forename: Satish
authors.identifier: 0000-0001-6731-6980
authors.initials: S
authors.lastname: Rattan
mesh_terms: D001003:Anal Canal / Q000502:physiology*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002147:Calmodulin / Q000378:metabolism*; D009119:Muscle Contraction / Q000502:physiology*; D009129:Muscle Tonus / Q000502:physiology; D009130:Muscle, Smooth / Q000502:physiology; D009219:Myosin-Light-Chain Kinase / Q000378:metabolism; D054460:rho-Associated Kinases / Q000378:metabolism; D020742:rhoA GTP-Binding Protein / Q000378:metabolism
chemical_list: D002147:Calmodulin; D054460:rho-Associated Kinases; D009219:Myosin-Light-Chain Kinase; D020742:rhoA GTP-Binding Protein; D002118:Calcium