title: Cowpox in a human, Russia, 2015.
abstract: We investigated the first laboratory-confirmed human case of cowpox virus infection in Russia since 1991. Phylogenetic studies of haemagglutinin, TNF-α receptor-like protein and thymidine kinase regions showed significant differences with known orthopoxviruses, including unique amino-acid substitutions and deletions. The described cowpox virus strain, taking into account differences, is genetically closely related to strains isolated years ago in the same geographical region (European part of Russia and Finland), which suggests circulation of viral strains with common origin in wild rodents without spread over long distances and appearance in other parts of the world.
authors.affiliation: Russian Federal Service for Surveillance on Consumer Rights Protection and Human Well-being,Moscow,Russia.
authors.forename: A Y
authors.initials: AY
authors.lastname: Popova
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: R A
authors.initials: RA
authors.lastname: Maksyutov
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: O S
authors.initials: OS
authors.lastname: Taranov
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: T V
authors.initials: TV
authors.lastname: Tregubchak
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Zaikovskaya
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Sergeev
authors.affiliation: County Hospital District of Kostroma No. 1,Kostroma Region,Russia.
authors.forename: I V
authors.initials: IV
authors.lastname: Vlashchenko
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Bodnev
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Ternovoi
authors.affiliation: Federal Budget Institution of Health 'Hygiene and Epidemiology Centre',Kostroma Region,Russia.
authors.forename: N S
authors.initials: NS
authors.lastname: Alexandrova
authors.affiliation: Russian Federal Service for Surveillance on Consumer Rights Protection and Human Well-being,Moscow,Russia.
authors.forename: A L
authors.initials: AL
authors.lastname: Tarasov
authors.affiliation: Russian Federal Service for Surveillance on Consumer Rights Protection and Human Well-being,Moscow,Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Konovalova
authors.affiliation: County Hospital District of Kostroma No. 1,Kostroma Region,Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Koroleva
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: L E
authors.initials: LE
authors.lastname: Bulychev
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Pyankov
authors.affiliation: Russian Federal Service for Surveillance on Consumer Rights Protection and Human Well-being,Moscow,Russia.
authors.forename: Y V
authors.initials: YV
authors.lastname: Demina
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: A P
authors.initials: AP
authors.lastname: Agafonov
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: S N
authors.initials: SN
authors.lastname: Shchelkunov
authors.affiliation: State Research Center of Virology and Biotechnology 'Vector',Koltsovo,Novosibirsk Region,Russia.
authors.forename: V N
authors.initials: VN
authors.lastname: Miheev
mesh_terms: D000293:Adolescent; D015605:Cowpox / Q000175:diagnosis*; D015608:Cowpox virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D010802:Phylogeny; D012426:Russia; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D014764:Viral Proteins / Q000235:genetics
chemical_list: D014764:Viral Proteins
keywords: Cowpox; Russia; phylogenetic studies; vaccine-like