title: Russian Keratoprosthesis in Stevens-Johnson Syndrome.
abstract: OBJECTIVE
  To evaluate the efficacy and safety of Moscow Eye Microsurgery Complex in Russia (MICOF) keratoprosthesis (KPro) implantation in patients with Stevens-Johnson syndrome (SJS).
  
  
  METHODS
  This was a retrospective case series. Fourteen eyes of 13 patients with SJS underwent KPro implantation at the Chinese People's Liberation Army General Hospital between April 1, 2000, and December 24, 2014. The visual outcome, KPro retention rate, and incidence of postoperative complications and their management were recorded and investigated.
  
  
  RESULTS
  The mean age and follow-up duration were 61.5 ± 17.3 years (range: 27-87 yrs) and 62 ± 39.1 months (range: 13-144 mo). Thirteen eyes (92.9%) achieved a best-corrected visual acuity of 20/200 or better, and 8 eyes (57.1%) achieved a best-corrected visual acuity of 20/40 or better after surgery. However, 71.4% (10/14) experienced visual decline because of different postoperative complications. Common complications included corneal melting, glaucoma, vitritis, superficial tissue overgrowth, and retroprosthetic membrane, and the incidence of these complications was 71.4%, 28.6%, 35.7%, 14.3%, and 28.6%, respectively. After repair and autoauricular cartilage reinforcement, all cases had stable anatomical retention at the last visit.
  
  
  CONCLUSIONS
  The MICOF KPro improved vision of patients with SJS, but lifelong surveillance is necessitated because of a high rate of postoperative complications. Corneal melting was the main reason for KPro failure. Infectious endophthalmitis and glaucoma were the main risk factors for visual loss.
authors.affiliation: *Department of Ophthalmology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China; †Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China; and ‡Department of Ophthalmology, Rocket Force General Hospital, Beijing, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Ma
authors.forename: Ran
authors.initials: R
authors.lastname: Xiang
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Meng
authors.forename: Limin
authors.initials: L
authors.lastname: Qin
authors.forename: Ying
authors.initials: Y
authors.lastname: Wu
authors.forename: Lei
authors.initials: L
authors.lastname: Tain
authors.forename: Yanming
authors.initials: Y
authors.lastname: Jiang
authors.forename: Yifei
authors.initials: Y
authors.lastname: Huang
authors.forename: Liqing
authors.initials: L
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001187:Artificial Organs; D003316:Corneal Diseases / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D012426:Russia; D013262:Stevens-Johnson Syndrome / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology