title: P(NMe2)3-Mediated Aziridination of Imines with α-Ketoesters for Synthesis of Aziridine-2-carboxylates.
abstract: Aziridination of N-sulfonyl imines with α-ketoesters in the presence of P(NMe2)3is reported. Adducts derived from trivalent phosphorus reagents and α-ketoesters are effectively intercepted by imines, affording a range of aziridine-2-carboxylates. The diastereoselectivity of the reaction depends on steric hindrance from substituents on the substrates.
authors.affiliation: Key Laboratory of Plant Resources and Chemistry of Arid Zones, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences , Urumqi 830011, China.|University of Chinese Academy of Sciences , Beijing 100049, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Jiang
authors.affiliation: Key Laboratory of Plant Resources and Chemistry of Arid Zones, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences , Urumqi 830011, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.affiliation: Key Laboratory of Plant Resources and Chemistry of Arid Zones, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences , Urumqi 830011, China.
authors.forename: Chong-Dao
authors.identifier: 0000-0001-8968-0134
authors.initials: CD
authors.lastname: Lu
authors.affiliation: Key Laboratory of Plant Resources and Chemistry of Arid Zones, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences , Urumqi 830011, China.
authors.forename: Yan-Jun
authors.initials: YJ
authors.lastname: Xu