title: Impact of IgE-mediated Food Allergy on Parental Quality of Life in Iranian Patients.
abstract: Food allergy is a common disorder especially in the first years of life. Strict avoidance of the responsible food is the most effective therapeutic measure so far. But this continuous vigilance could be stressful for the patient and family and decreases their quality of life (QOL). This survey was designed to evaluate the impact of IgE-mediated food allergy on parental QOL in Iranian patients and to develop a valid Persian version of "Food Allergy Quality Of Life- Parental Burden (FAQL-PB) questionnaire". 90 patients (28 females, 62 males) and their parents who were referred to the clinic of Allergy in Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran were enrolled. The questionnaire was translated with scientific method and its reliability was approved in a pilot study (ICC=0.75, cronbach-α=0.90). Among all patients the most common allergens were wheat (60%) and cow's milk (42%). The patient's age (p=0.02), parent's gender (p=0.004), mother's age (p=0.02), duration of the disease (p=0.048), and allergen multiplicity (p=0.004) were found to have the most significant correlation with family and social activity (FSA) domain. The most meaningful associations were achieved between parent's gender (p<0.001) and emotional issues (EM); as well as meal preparation (MP) with patient's age (p=0.02), parent's gender (p<0.0001) and also allergen multiplicity (p= 0.003); likewise nutrition and health concern (NH) domain with parent's gender (p<0.001). Anaphylaxis's history did not place any burden on each domain. It was concluded that presence of food allergic patients in families could considerably affect all domains of QOL.
authors.affiliation: Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Seyed Mohammad
authors.initials: SM
authors.lastname: Fathi
authors.affiliation: Department of Allergy and Clinical Immunology, Shahid Bahonar Hospital, Alborz University of Medical Sciences, Karaj, Iran.
authors.forename: Marzieh
authors.initials: M
authors.lastname: Tavakol
authors.affiliation: Molecular Immunology Research Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Research Center for Primary Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Nima
authors.initials: N
authors.lastname: Rezaei
authors.affiliation: Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Movahedi
authors.affiliation: Molecular Immunology Research Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Asghar
authors.initials: A
authors.lastname: Aghamohammadi
authors.affiliation: Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mansoureh
authors.initials: M
authors.lastname: Shariat
authors.affiliation: Molecular Immunology Research Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Bamdad
authors.initials: B
authors.lastname: Sadeghi
authors.affiliation: Department of Allergy and Clinical Immunology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Behniafard
authors.affiliation: Department of Allergy and Clinical Immunology, Ilam University of Medical Sciences, Ilam, Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Darabi
authors.affiliation: Faculty of Medicine,Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Hajikhani
authors.affiliation: School of Public Health, Arak University of Medical Sciences, Arak, Iran AND Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Abdollahpour
authors.affiliation: Department of Allergy and Clinical Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Gharagozlou
mesh_terms: D002675:Child, Preschool; D017281:Cost of Illness; D005260:Female; D005512:Food Hypersensitivity; D006801:Humans; D007073:Immunoglobulin E; D007492:Iran; D008297:Male; D008875:Middle Aged; D010290:Parents; D011788:Quality of Life; D012737:Sex Factors; D013315:Stress, Psychological
chemical_list: D007073:Immunoglobulin E
keywords: Food allergy; Food hypersensitivity; Iran; Quality of life; Questionnaire