title: Effects of Endurance and Endurance-strength Exercise on Renal Function in Abdominally Obese Women with Renal Hyperfiltration: A Prospective Randomized Trial.
abstract: OBJECTIVE
  Obesity is associated with kidney defects. Physical activity is a key element in the treatment of obesity. The aim of this study was to compare the effect of endurance and endurance-strength training on kidney function in abdominally obese women.
  
  
  METHODS
  Forty-four abdominally obese women were randomized to endurance training or endurance-strength training, three times a week for 3 months. Before and after the intervention, kidney function was assessed by measuring blood creatinine, urine creatinine, and urine albumin levels, and the albumin-to-creatinine ratio and glomerular filtration rate (GFR) were calculated.
  
  
  RESULTS
  Renal hyperperfusion was present in both groups before the study. Following both types of physical activity, similar modifications of the investigated parameters were observed, but with no significant between-group differences. Both courses of training led to a significant increase in blood creatinine and a subsequent decrease in the GFR. A significant increase in urine creatinine and album levels, though not exceeding the range for microalbuminuria, was not accompanied by any difference in the albumin-to-creatinine ratio after endurance-strength training alone.
  
  
  CONCLUSIONS
  Three months of either endurance or endurance-strength training has a favorable and comparable effect on renal function in abdominally obese women with renal hyperfiltration.
authors.affiliation: Department of Education and Obesity Treatment and Metabolic Disorders, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland.
authors.forename: Monika
authors.initials: M
authors.lastname: Szulińska
authors.affiliation: Department of Internal Medicine, Metabolic Disorders and Hypertension, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland.
authors.forename: Damian
authors.initials: D
authors.lastname: Skrypnik
authors.affiliation: Department of Physiology, Biochemistry and Hygiene, Poznań University School of Physical Education, ul. Królowej Jadwigi 27/39, 61-871 Poznań, Poland.
authors.forename: Marzena
authors.initials: M
authors.lastname: Ratajczak
authors.affiliation: Department of Physiology, Biochemistry and Hygiene, Poznań University School of Physical Education, ul. Królowej Jadwigi 27/39, 61-871 Poznań, Poland.
authors.forename: Joanna
authors.initials: J
authors.lastname: Karolkiewicz
authors.affiliation: Department of Physiology, Poznań University of Medical Sciences, ul. Swiecickiego 6, 60-781 Poznań, Poland.
authors.forename: Edyta
authors.initials: E
authors.lastname: Madry
authors.affiliation: Department of Education and Obesity Treatment and Metabolic Disorders, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Musialik
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, ul. Szpitalna 27/33, 60-572 Poznań, Poland.
authors.forename: Jaroslaw
authors.initials: J
authors.lastname: Walkowiak
authors.affiliation: Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers University, New Jersey Medical School, International Center for Public Health, 225 Warren Street, Room E230P Newark, New Jersey 07103-3535, USA; Department of Biochemistry and Biotechnology, Poznań University of Life Sciences, Dojazd Str. 11, 60-632 Poznan, Poland; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego Str. 12/14, 61-704 Poznan, Poland.
authors.forename: Hieronim
authors.initials: H
authors.lastname: Jakubowski
authors.affiliation: Department of Education and Obesity Treatment and Metabolic Disorders, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland.
authors.forename: Pawel
authors.initials: P
authors.lastname: Bogdański
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D010807:Physical Endurance; D011446:Prospective Studies; D055070:Resistance Training; D055815:Young Adult
chemical_list: D003404:Creatinine
keywords: Abdominal obesity; Physical exercise; Renal function