title: Effect of Lichen Sclerosis on Success of Urethroplasty.
abstract: Lichen sclerosis (LS) is a chronic, relapsing disease with a variable presentation. In men, genitourinary LS may affect the penile foreskin, glans, meatus, and urethra. Treatment is multifaceted, ranging from pharmacotherapy to surgery. Urethral reconstruction due to stricture disease from LS is frequently plagued by a high recurrence rate. At the authors' institution, the high recurrence rate has shifted their practice toward potent steroids and minimally invasive surgical techniques. Management of recurrence includes dilation, meatotomy/meatoplasty, 1-stage and 2-stage repairs. Recalcitrant cases may necessitate abandonment of most of the urethra resulting in a perineal urethrostomy.
authors.affiliation: Division of Urology, Department of Surgery, Duke University Medical Center, DUMC 3146, Durham, NC 27710, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Granieri
authors.affiliation: Division of Urology, Department of Surgery, Duke University Medical Center, DUMC 3146, Durham, NC 27710, USA. Electronic address: Drew.Peterson@duke.edu.
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Peterson
authors.affiliation: Division of Urology, Department of Surgery, Duke University Medical Center, DUMC 3146, Durham, NC 27710, USA.
authors.forename: Ramiro J
authors.initials: RJ
authors.lastname: Madden-Fuentes
mesh_terms: D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000150:complications*; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods*; D016896:Treatment Outcome; D014521:Urethra / Q000601:surgery*; D014525:Urethral Stricture / Q000209:etiology* / Q000601:surgery; D013521:Urologic Surgical Procedures, Male / Q000379:methods*
keywords: Balanitis xerotica obliterans; Lichen sclerosis; Perineal urethrostomy; Urethral stricture; Urethroplasty