title: Adenoma Prevalence and Distribution Among US Latino Subgroups Undergoing Screening Colonoscopy.
abstract: Colorectal cancer (CRC) is the second leading malignancy diagnosed among US Latinos. Latinos in the USA represent a heterogeneous amalgam of subgroups varying in genetic background, culture, and socioeconomic status. Little is known about the frequency of CRC precursor lesions found at screening colonoscopy among Latino subgroups.
  
  
  
  The aim was to determine the prevalence and distribution of histologically confirmed adenomas found at screening colonoscopy among average-risk, asymptomatic US Latinos according to their subgroup and socio-demographic background.
  
  
  
  Cross-sectional analysis of pathological findings resulting from screening colonoscopy among average-risk, asymptomatic US Latinos aged ≥50 in two prospective randomized controlled trials at an academic medical center.
  
  
  
  Among the 561 Latinos who completed screening colonoscopy, the two largest subgroups were Puerto Ricans and Dominicans. The findings among both subgroups were: adenomas 30.6%, proximal adenomas 23.5%, advanced adenomas 12.0%, and proximal advanced adenomas 8.9%. These rates are at least as high as those found at screening colonoscopy among US whites. While Puerto Ricans were more likely than Dominicans to be born in the USA, speak English, be acculturated, have a smoking history, and be obese, there were no significant differences in adenoma rates between these subgroups.
  
  
  
  The prevalence of adenomas, advanced adenomas, and proximal neoplasia was high among both subgroups. These findings have implications for CRC screening and surveillance among the increasingly growing Latino population in the USA.
authors.affiliation: UPMC Montefiore Hospital, N715, 200 Lothrop Street, Pittsburgh, PA, 15213, USA. svchablani@gmail.com.|Departments of Gastroenterology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. svchablani@gmail.com.
authors.forename: Sumedha V
authors.initials: SV
authors.lastname: Chablani
authors.affiliation: Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY, 10029, USA.|Departments of Gastroenterology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Lina
authors.initials: L
authors.lastname: Jandorf
authors.affiliation: Department of Psychiatry, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, 7th Floor, New York, NY, 10022, USA.|Departments of Gastroenterology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: DuHamel
authors.affiliation: Digestive Healthcare Center, 511 Courtyard Drive, Building 500, Hillsborough, NJ, 08844, USA.|Departments of Gastroenterology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Kristen K
authors.initials: KK
authors.lastname: Lee
authors.affiliation: Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY, 10029, USA.|Departments of Gastroenterology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Pathu
authors.initials: P
authors.lastname: Sriphanlop
authors.affiliation: Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY, 10029, USA.|Departments of Gastroenterology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Cristina
authors.initials: C
authors.lastname: Villagra
authors.affiliation: Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1069, New York, NY, 10029, USA.|Departments of Gastroenterology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Steven H
authors.initials: SH
authors.lastname: Itzkowitz
mesh_terms: D000069:Acculturation; D000236:Adenoma / Q000000981:diagnostic imaging / Q000208:ethnology* / Q000473:pathology*; D000367:Age Factors; D000368:Aged; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000208:ethnology* / Q000473:pathology*; D003430:Cross-Sectional Studies; D004293:Dominican Republic / Q000208:ethnology; D055088:Early Detection of Cancer; D004641:Emigration and Immigration; D005260:Female; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D011647:Puerto Rico / Q000208:ethnology; D012907:Smoking / Q000208:ethnology; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology
keywords: Adenoma; Colonoscopy; Colorectal cancer; Latinos; Screening