title: Metaplastic squamous cell carcinoma of the breast: A case report and literature review.
abstract: Metaplastic tumors are rare and represent a heterogeneous group of neoplasms showing dominant areas of non-glandular differentiation. Etiology and pathogenesis of this type of lesion in the breast is uncertain. The most common sources of metastatic squamous cell carcinoma of the breast are lung, esophagus, cervix, and urinary bladder. Squamous cell carcinomas may present clinically with inflammation and average size greater than breast adenocarcinoma. As for imaging studies, mammography shows no typical findings and ultrasound can show a complicated cyst or an inflammatory process, among the differential diagnoses. Therefore, knowing this pathological entity, its clinical course and imaging findings is important to safely treat such a rare and aggressive disease. We herein report a case of metaplastic carcinoma, squamous subtype, diagnosed by core needle biopsy.
authors.affiliation: MD - Radiologist at Gimi Medicina Diagnóstica, São Paulo, SP, Brazil.
authors.forename: Luciana
authors.initials: L
authors.lastname: Graziano
authors.affiliation: MD - Radiologist at Gimi Medicina Diagnóstica, São Paulo, SP, Brazil.
authors.forename: Paschoal
authors.initials: P
authors.lastname: Graziano
authors.affiliation: PhD - Radiologist at AC Camargo Cancer Center, São Paulo, SP, Brazil.
authors.forename: Almir Galvão Vieira
authors.initials: AG
authors.lastname: Bitencourt
authors.affiliation: MD - Radiologist at Gimi Medicina Diagnóstica, São Paulo, SP, Brazil.
authors.forename: Daniel Bernal
authors.initials: DB
authors.lastname: Soto
authors.affiliation: MD - Radiologist at Gimi Medicina Diagnóstica, São Paulo, SP, Brazil.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Hiro
authors.affiliation: MD - Pathologist at CDAP - Clínica de Diagnóstico Anátomo-Patológico, São Paulo, SP, Brazil.
authors.forename: Cíntia Camillo
authors.initials: CC
authors.lastname: Nunes
mesh_terms: D062005:Biopsy, Large-Core Needle / Q000379:methods; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008327:Mammography; D008679:Metaplasia / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D018615:Ultrasonography, Doppler, Color