title: Effects of ocular and systemic factors on the progression of glaucomatous visual field damage in various sectors.
abstract: To investigate the effects of ocular and systemic risk factors for glaucomatous progression in different sectors of the visual field (VF).
  
  
  
  409 eyes from 268 patients with 10 reliable VFs from the Japanese Archive of Multicentral Databases in Glaucoma (JAMDIG) were investigated. VFs were divided into six sectors (mean total deviation (mTD)s20+, mTDs10-20and mTDs0-10, >20°, 10-20° and <10° in the superior hemifield, respectively; and mTDi20+, mTDi10-20and mTDi0-10, >20°, 10-20° and <10° in the inferior hemifield, respectively). The relationship between sectorial progression rate and eight variables (age, mTD at baseline VF, average intraocular pressure (IOP), SD of IOP, systemic hypertension, migraine, family history of glaucoma and smoking status) was investigated.
  
  
  
  The mTD progression rate was -0.21 dB/year. Older age was related to progression of mTDs20+, mTDs10-20, mTDi20+and mTDi10-20. Mean IOP was not related to progression in any VF sector; however, a larger SD of IOP was related to progression of mTDs20+, mTDi0-10, mTDi10-20and mTDi20+. Smoking status was related to progression in all inferior VF sectors (mTDi0-10, mTDi10-20and mTDi20+).
  
  
  
  Smoking status is related to glaucomatous VF progression in all sectors of the inferior hemifield.
authors.affiliation: Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Asaoka
authors.affiliation: Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Murata
authors.affiliation: Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Fujino
authors.affiliation: Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.|Orthoptics and Visual Science, Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Hirasawa
authors.affiliation: Department of Ophthalmology, Shimane University Faculty of Medicine, Shimane, Japan.|Division of Ophthalmology, Matsue Red Cross Hospital, Shimane, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Tanito
authors.affiliation: Department of Ophthalmology, Ehime University Graduate School of Medicine, Ehime, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Mizoue
authors.affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Mori
authors.affiliation: Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Suzuki
authors.affiliation: Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Yamashita
authors.affiliation: Department of Ophthalmology, University of Yamanashi Faculty of Medicine, Yamanashi, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kashiwagi
authors.affiliation: Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Atsuya
authors.initials: A
authors.lastname: Miki
authors.affiliation: Orthoptics and Visual Science, Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Shoji
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology; D015337:Multicenter Studies as Topic; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects* / Q000503:physiopathology; D014794:Visual Fields / Q000502:physiology*; D055815:Young Adult
keywords: Glaucoma