title: Simultaneous microextraction of inorganic iodine and iodinated amino acids by miniaturized matrix solid-phase dispersion with molecular sieves and ionic liquids.
abstract: This study presents an effective method of using miniaturized matrix solid phase dispersion (MSPD) for the microextraction of inorganic iodine and iodinated amino acids from seaweed samples. Quantification of the target analytes was performed by ultrahigh performance liquid chromatography with UV detection. Molecular sieve (SBA-15) was chosen as the dispersing adsorbent with an ionic liquid (1-dodecyl-3-methylimidazolium bromide) as the elution solvent. The experimental conditions for the MSPD, such as the type of sorbent, ratio of sorbent to sample, type and concentration of the elution solvent, and grinding time were evaluated and optimized. Under the final working conditions, good recoveries were obtained in the range of 86.5-95.4%, with relative standard deviation values below 6.0% in all cases. The limits of detection and limits of quantitation were in the ranges of 3.7-16.7ng/mL and 12.4ng/mL, respectively. Compared with common ultrasound assisted extraction, the advantages of this green approach are low consumption of the sorbent and solvent, short extraction time and good selectivity, even in complicated matrices. The proposed SBA-15-based MSPD method was successfully applied to the microextraction of potassium iodide, 3-iodo-l-tyrosine, and 3,5-diiodo-l-tyrosine from kelp, nori and undaria pinnatifida, respectively.
authors.affiliation: College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China. Electronic address: caojun91@163.com.
authors.forename: Jun
authors.initials: J
authors.lastname: Cao
authors.affiliation: College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China.
authors.forename: Li-Qing
authors.initials: LQ
authors.lastname: Peng
authors.affiliation: College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Xu
authors.affiliation: College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China.
authors.forename: Li-Jing
authors.initials: LJ
authors.lastname: Du
authors.affiliation: College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China.
authors.forename: Qi-Dong
authors.initials: QD
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D000596:Amino Acids / Q000302:isolation & purification*; D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D007093:Imidazoles / Q000737:chemistry; D007455:Iodine / Q000302:isolation & purification*; D052578:Ionic Liquids / Q000737:chemistry*; D057230:Limit of Detection; D016062:Porosity; D015203:Reproducibility of Results; D012624:Seaweed / Q000737:chemistry / Q000648:ultrastructure; D012822:Silicon Dioxide / Q000737:chemistry; D052616:Solid Phase Extraction / Q000379:methods*; D012997:Solvents / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013997:Time Factors
chemical_list: C521425:1-dodecyl-3-methylimidazolium; D000596:Amino Acids; D007093:Imidazoles; D052578:Ionic Liquids; C509969:SBA-15; D012997:Solvents; D012822:Silicon Dioxide; D007455:Iodine
keywords: Iodine; Ionic liquid; Matrix solid phase dispersion; Molecular sieve; Seaweed; Ultrahigh performance liquid chromatography