title: [Application of combination of xenoskin with delayed microskin graft in extensively burned patients].
abstract: To observe clinical effects of combination of acellular porcine skin with delayed microskin graft on extensively burned patients.  Methods: Forty extensively burned patients were assigned into a treatment group and a control group. In the treatment group, 20 patients were covered with acellular porcine skin after escharectomy, and the delayed microskin grafting was performed 5 days later. In the control group, 20 patients were covered with allograft skin combined with microskin graft after escharectomy. The cure rate, the graft survival rate, wound healing time and cost per 1% wound were observed.  Results: The cure rate for the 2 groups was the same (90%), and wound healing time was similar between the two groups (P>0.05). The graft survival rate in the treatment group was higher than that in the control group (P<0.05), and cost per 1% wound in the treatment group was less than that in the control group (P<0.05).  Conclusion: The combination of acellular porcine skin with delayed microskin graft is an effective method to treat extensively burned patients, and it provides an ideal substitute for allograft skin combined with microskin graft.
authors.affiliation: Department of Burns and Plastic Surgery, Xiangtan Central Hospital, Xiangtan Hunan 411100, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Burns and Plastic Surgery, Xiangtan Central Hospital, Xiangtan Hunan 411100, China.
authors.forename: Weifeng
authors.initials: W
authors.lastname: Liu
authors.affiliation: Department of Burns and Plastic Surgery, Xiangtan Central Hospital, Xiangtan Hunan 411100, China.
authors.forename: Renwu
authors.initials: R
authors.lastname: Jiang
authors.affiliation: Department of Burns and Plastic Surgery, Xiangtan Central Hospital, Xiangtan Hunan 411100, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Burns and Plastic Surgery, Xiangtan Central Hospital, Xiangtan Hunan 411100, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.affiliation: Department of Burns and Plastic Surgery, Xiangtan Central Hospital, Xiangtan Hunan 411100, China.
authors.forename: Pingzhi
authors.initials: P
authors.lastname: Zou
mesh_terms: D062088:Acellular Dermis / Q000191:economics* / Q000706:statistics & numerical data*; D000818:Animals; D001684:Biological Dressings / Q000191:economics* / Q000706:statistics & numerical data*; D002056:Burns / Q000628:therapy*; D003362:Cost-Benefit Analysis; D006085:Graft Survival; D006801:Humans; D016038:Skin Transplantation / Q000191:economics / Q000379:methods*; D013552:Swine; D014184:Transplantation, Homologous / Q000009:adverse effects / Q000191:economics / Q000379:methods; D014945:Wound Healing