title: Oxime Based Selective Fluorescent Sensor for Arsenate Ion in a Greener Way with Bio-Imaging Application.
abstract: A newly designed oxime based probe, 2,4-dihydroxyacetophenone-oxime (DHAO), was found to recognize H2AsO4-selectively with ∼3 fold "turn-on" fluorescence enhancement and LOD of 29 μM, K = (2.10 ± 0.54) × 104M-1in purely aqueous medium. The structures of the DHAO and its adduct with H2AsO4-were optimized by DFT calculations. Intracellular imaging of As(V) in HepG2 cells demonstrate the possibilities of in vitro/in vivo applications for selective monitoring of such species.
authors.affiliation: Department of Chemistry, Jadavpur University.
authors.forename: Malay
authors.initials: M
authors.lastname: Dolai
authors.forename: Rabiul
authors.initials: R
authors.lastname: Alam
authors.forename: Atul
authors.initials: A
authors.lastname: Katarkar
authors.forename: Keya
authors.initials: K
authors.lastname: Chaudhuri
authors.forename: Mahammad
authors.initials: M
authors.lastname: Ali
mesh_terms: D001149:Arsenates / Q000032:analysis*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D061848:Optical Imaging / Q000379:methods*; D010091:Oximes / Q000737:chemistry*
chemical_list: D001149:Arsenates; D005456:Fluorescent Dyes; D010091:Oximes; C025657:arsenic acid