title: [Perioperative safety analysis of carotid endarterectomy in diabetic patients].
abstract: Objective:To compare perioperative outcome of carotid endarterectomy (CEA) between diabetic and non-diabetic patients and discuss the safety of CEA in diabetic patients.Methods:A total of 572 patients with carotid stenosis who underwent CEA from Juanuary 2006 to September 2014 in Peking Union Medical Colloge Hospital were collected and analyzed retrospectively. The patients were distributed into diabetes mellitus (DM) group and non-DM group according to the comorbidities. Their baseline characteristics, intraoperative index and major complications in perioperative period were analyzed and compared.Results:Of 572 cases, 184 had DM (32.2%). Diabetic patients more frequently had a history of coronary artery disease (30.4% vs 18.6%), peripheral artery disease (39.7% vs 27.3%), and hyperlipemia (50.5% vs 36.6%) than non-diabetic patients (allP<0.05). The incidence of perioperative myocardial infarction (0.5% vs 0.8%), stroke (1.6% vs 1.8%) and death (0.5% vs 0.3%) did not differ between two groups (allP>0.05). Data of follow-up was available in 89.6% of patients, with a median duration of 42 months. The incidence of myocardial infarction (4.3% vs 3.4%), stroke (1.8% vs 1.7%), death (1.1% vs 0.9%), and restenosis (2.9% vs 3.1%) did not differ between two groups (allP>0.05).Conclusion:DM does not increase the risk of perioperative complications and impair the long-term outcomes after CEA if the patients are appropriately evaluated and treated in perioperative period.
authors.affiliation: Department of Vascular Surgery, Peking Union Medical Colloge Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing 100730, China.
authors.forename: X N
authors.initials: XN
authors.lastname: Liu
authors.forename: L
authors.initials: L
authors.lastname: Ni
authors.forename: W D
authors.initials: WD
authors.lastname: Wang
authors.forename: R
authors.initials: R
authors.lastname: Zeng
authors.forename: C W
authors.initials: CW
authors.lastname: Liu
mesh_terms: D016893:Carotid Stenosis; D015897:Comorbidity; D003324:Coronary Artery Disease; D048909:Diabetes Complications; D003920:Diabetes Mellitus; D016894:Endarterectomy, Carotid; D006801:Humans; D015994:Incidence; D009203:Myocardial Infarction; D058729:Peripheral Arterial Disease; D012189:Retrospective Studies; D012307:Risk Factors; D012449:Safety; D020521:Stroke; D016896:Treatment Outcome