title: Impact of cardiac arrest resuscitated donors on heart transplant recipients' outcome.
abstract: To evaluate the influence of cardiac arrest-resuscitated donors (CARDs) on the outcome of heart recipients.
  
  
  
  Patients transplanted between July 2004 and December 2012 were divided into 2 groups according to the history of cardiac arrest in donors and their clinical records were retrospectively reviewed.
  
  
  
  A total of 584 heart transplantations were performed during the study period, and 117 recipients received an organ from a CARD. There were no differences between the 2 groups with regards to recipient age, sex, cardiomyopathy, preoperative extracorporeal membrane oxygenation, national high emergency waiting list, and redo surgery. Donors who sustained a cardiac arrest were significantly younger (44 [32-51] vs 49 [41-56] years; P < .001), their main cause of death was anoxia (57% vs 1%; P < .001), and they had significantly greater troponin T peak levels (0.51 [0.128-3.108] vs 0.11 [0.04-0.43] ng/mL; P < .001). Median cardiac arrest duration was 15 minutes (5-25). No difference was noted in donors with regards to left ventricular ejection fraction at time of organ procurement (62% ± 8% vs 63% ± 8%; P = .2). There were no differences between the 2 groups with regards to ischemic time (179 ± 60 vs 183 ± 59 minutes; P = .43), need for postoperative extracorporeal membrane oxygenation for primary graft failure (31% vs 30%; P = .993) and 30-days mortality. Recipients receiving an organ from a CARD had a significantly better 10 year survival (69.4% vs 50.4%; P = .017).
  
  
  
  History of cardiac arrest in donors with a preserved left ventricular ejection fraction at time of organ procurement doesn't affect outcome of heart recipients.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France. Electronic address: a.galeone@email.it.
authors.forename: Antonella
authors.initials: A
authors.lastname: Galeone
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: Shaida
authors.initials: S
authors.lastname: Varnous
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Lebreton
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: Eleodoro
authors.initials: E
authors.lastname: Barreda
authors.affiliation: Department of Anesthesiology, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: Sara
authors.initials: S
authors.lastname: Hariri
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Pavie
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Leprince
mesh_terms: D000328:Adult; D016887:Cardiopulmonary Resuscitation; D046148:Donor Selection; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006085:Graft Survival; D006323:Heart Arrest / Q000628:therapy*; D006333:Heart Failure / Q000401:mortality / Q000601:surgery*; D016027:Heart Transplantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000379:methods; D066027:Transplant Recipients; D016896:Treatment Outcome; D014850:Waiting Lists / Q000401:mortality
keywords: cardiac arrest; heart donor; heart recipient; heart transplantation; outcome