title: Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons.
authors.affiliation: Department of Medicine, University of Illinois at Chicago, Chicago, IL.|Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
authors.forename: Vinzon
authors.initials: V
authors.lastname: Ibanez
authors.affiliation: Department of Medicine, University of Illinois at Chicago, Chicago, IL.|Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
authors.forename: Kestis
authors.initials: K
authors.lastname: Vaitkus
authors.affiliation: Jesse Brown Veterans Affairs Medical Center, Chicago, IL.|Department of Pediatrics, University of Illinois at Chicago, Chicago, IL; and.
authors.forename: Angela
authors.initials: A
authors.lastname: Rivers
authors.affiliation: Department of Medicine, University of Illinois at Chicago, Chicago, IL.|Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
authors.forename: Robert
authors.initials: R
authors.lastname: Molokie
authors.affiliation: Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI.
authors.forename: Shuaiying
authors.initials: S
authors.lastname: Cui
authors.affiliation: Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI.
authors.forename: James Douglas
authors.initials: JD
authors.lastname: Engel
authors.affiliation: Department of Medicine, University of Illinois at Chicago, Chicago, IL.|Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
authors.forename: Joseph
authors.initials: J
authors.lastname: DeSimone
authors.affiliation: Department of Medicine, University of Illinois at Chicago, Chicago, IL.|Jesse Brown Veterans Affairs Medical Center, Chicago, IL.
authors.forename: Donald
authors.identifier: 0000-0002-0275-7168
authors.initials: D
authors.lastname: Lavelle
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood* / Q000188:drug therapy*; D000818:Animals; D004353:Drug Evaluation, Preclinical; D004791:Enzyme Inhibitors / Q000009:adverse effects / Q000494:pharmacology*; D005319:Fetal Hemoglobin / Q000378:metabolism*; D056466:Histone Demethylases / Q000037:antagonists & inhibitors*; D010215:Papio; D012235:Rhodamines / Q000009:adverse effects / Q000494:pharmacology*; D013141:Spiro Compounds / Q000009:adverse effects / Q000494:pharmacology*; D013876:Thiophenes / Q000009:adverse effects / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; C547335:RN1 compound; D012235:Rhodamines; D013141:Spiro Compounds; D013876:Thiophenes; D005319:Fetal Hemoglobin; D056466:Histone Demethylases