title: Regenerative Endodontic Procedures: Clinical Outcomes.
abstract: Immature teeth are at risk for pulp necrosis, resulting in arrested root development and poor long-term prognosis. There is growing evidence that regenerative endodontic procedures promote desirable clinical outcomes. Despite significant advances in the field of regenerative endodontics and acceptable clinical outcomes, current evidence suggests that the tissues formed following currently used procedures do not completely recapitulate the former pulp-dentin complex. Further research is needed to identify prognostic factors and predictors of successful outcomes and to develop different treatment strategies to better predictably achieve all identified clinical outcomes, while favoring tissue formation that more closely resembles the pulp-dentin complex.
authors.affiliation: Department of Endodontics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA. Electronic address: Diogenes@uthscsa.edu.
authors.forename: Anibal
authors.initials: A
authors.lastname: Diogenes
authors.affiliation: Department of Endodontics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
authors.forename: Nikita B
authors.initials: NB
authors.lastname: Ruparel
mesh_terms: D003782:Dental Pulp / Q000502:physiology*; D003790:Dental Pulp Necrosis / Q000601:surgery*; D006801:Humans; D019647:Oral Surgical Procedures / Q000379:methods; D012038:Regeneration; D033581:Stem Cell Transplantation; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D016896:Treatment Outcome
keywords: Immature teeth; Regenerative endodontics; Revascularization; Revitalization; Root development