title: Genome sequence of a commensal bacterium,Enterococcus faecalisCBA7120, isolated from a Korean fecal sample.
abstract: BACKGROUND
  Enterococcus faecalis, the type strain of the genusEnterococcus, is not only a commensal bacterium in the gastrointestinal tract in vertebrates and invertebrates, but also causes serious disease as an opportunistic pathogen. To date, genome sequences have been published for over four hundredE. faecalisstrains; however, pathogenicity of these microbes remains complicated. To increase our knowledge ofE. faecalisvirulence factors, we isolated strain CBA7120 from the feces of an 81-year-old female from the Republic of Korea and performed a comparative genomic analysis.
  
  
  RESULTS
  The genome sequence ofE. faecalisCBA7120 is 3,134,087 bp in length, with a G + C content of 37.35 mol%, and is comprised of four contigs with an N50 value of 2,922,046 bp. The genome showed high similarity with other strains ofE. faecalis, including OG1RF, T13, 12107 and T20, based on OrthoANI values. Strain CBA7120 contains 374 pan-genome orthologous groups (POGs) as singletons, including "Phages, Prophages, Transposable elements, Plasmids," "Carbohydrates," "DNA metabolism," and "Virulence, Disease and Defense" subsystems. Genes related to multidrug resistance efflux pumps were annotated in the genome.
  
  
  CONCLUSIONS
  The comparative genomic analysis ofE. faecalisstrains presented in this study was performed using a variety of analysis methods and will facilitate future identification of hypothetical proteins.
authors.affiliation: Biological Disaster Analysis Group, Korea Basic Science Institute, Daejeon, 34133 South Korea.
authors.forename: Joon Yong
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Biological Disaster Analysis Group, Korea Basic Science Institute, Daejeon, 34133 South Korea.|Department of Food Science and Engineering, Ewha Womans University, Seoul, 03760 South Korea.
authors.forename: Hye Seon
authors.initials: HS
authors.lastname: Song
authors.affiliation: Biological Disaster Analysis Group, Korea Basic Science Institute, Daejeon, 34133 South Korea.|Department of Food Science and Engineering, Ewha Womans University, Seoul, 03760 South Korea.
authors.forename: Yeon Bee
authors.initials: YB
authors.lastname: Kim
authors.affiliation: Biological Disaster Analysis Group, Korea Basic Science Institute, Daejeon, 34133 South Korea.
authors.forename: Joseph
authors.initials: J
authors.lastname: Kwon
authors.affiliation: Biological Disaster Analysis Group, Korea Basic Science Institute, Daejeon, 34133 South Korea.
authors.forename: Jong-Soon
authors.initials: JS
authors.lastname: Choi
authors.affiliation: ChunLab Inc., Seoul National University, Seoul, 151-742 South Korea.
authors.forename: Yong-Joon
authors.initials: YJ
authors.lastname: Cho
authors.affiliation: ChunLab Inc., Seoul National University, Seoul, 151-742 South Korea.
authors.forename: Byung-Yong
authors.initials: BY
authors.lastname: Kim
authors.affiliation: Department of Food Science and Engineering, Ewha Womans University, Seoul, 03760 South Korea.
authors.forename: Jin-Kyu
authors.initials: JK
authors.lastname: Rhee
authors.affiliation: Korea Zoonosis Research Institute, Chonbuk National University, Jeonju, 561-756 South Korea.
authors.forename: Jinjong
authors.initials: J
authors.lastname: Myoung
authors.affiliation: Research Group of Gut Microbiome, Korea Food Research Institute, Seongnam, 13539 South Korea.|University of Science and Technology, Daejeon, 34113 South Korea.
authors.forename: Young-Do
authors.initials: YD
authors.lastname: Nam
authors.affiliation: Biological Disaster Analysis Group, Korea Basic Science Institute, Daejeon, 34133 South Korea.|University of Science and Technology, Daejeon, 34113 South Korea.
authors.forename: Seong Woon
authors.initials: SW
authors.lastname: Roh
keywords: Comparative genomics; Enterococcus faecalis; Genome sequence; Virulence factors