title: [Precancerous lesions of the buccal epithelium].
abstract: Squamous cell carcinomas of the oral cavity and lips consistently have a high incidence (they constitute the fifth most common form of cancer in France) and carry a heavy prognosis, particularly if diagnosed late. According to different studies, between 10 and 80% of such carcinomas occur in a pre-existing or precancerous lesion. The World Health Organisation (WHO) recommends the use of two terms for such lesions: precursor lesions, i.e. histological lesions associated with intraepithelial neoplasia (IEN) and verrucous hyperplasia (VH), frequently resulting clinically in leukoplakia or erythroplakia; "at risk" lesions, which include lichen planus, submucosal oral fibrosis and certain forms of genodermatosis.
authors.affiliation: Service de dermatologie, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France. Electronic address: catherine.vilmer@sls.aphp.fr.
authors.forename: C
authors.initials: C
authors.lastname: Renaud-Vilmer
authors.affiliation: Service de pathologie, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Cavelier-Balloy
mesh_terms: D002278:Carcinoma in Situ / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D018289:Carcinoma, Verrucous / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D003430:Cross-Sectional Studies; D057210:Delayed Diagnosis; D004919:Erythroplasia / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D007972:Leukoplakia, Oral / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D008046:Lip / Q000473:pathology; D008048:Lip Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D012307:Risk Factors
keywords: Erythroplakia; Florid oral papillomatosis; Hyperplasie épithéliale verruqueuse; Leucoplakia; Leucoplasie; Leucoplasie verruqueuse proliférative; Lichen plan; Lichen planus; Lésions précancéreuses buccales; Néoplasies intra-épithéliales orales; Oral intraepithelial neoplasia; Papillomatose orale floride; Precancerous oral lesions; Proliferative verrucous hyperplasia; Verrucous hyperplasia; Érythroplasie