title: [Association of Deep Venous Thrombosis with D-dimer Values in Patients with Hemorrhagic Stroke].
abstract: Pulmonary embolism(PE)in the early phase of stroke worsens the prognosis. It is necessary to detect deep venous thrombosis(DVT)to avoid PE. We conducted the D-dimer screening in order to detect DVT at an earlier stage. We retrospectively analyzed the clinical data of patients with hemorrhagic stroke who were admitted to the local stroke center, and investigated the complication rates of DVT, PE, D-dimer values, and risk factors of DVT. From October 2012 to August 2014, 261 patients were included. DVT was detected in 46 patients(17.6%)and anticoagulant therapy was started in 5 patients with central DVT. PE did not occur during this observation period. The D-dimer cutoff value for estimating the presence of the DVT was 8.9μg/mL, and the risk factors for DVT were older age, severe neurological disability, prolonged hospital stays, and subarachnoid hemorrhage. D-dimer screening is very useful to make earlier diagnosis and treatment of DVT.
authors.affiliation: Department of Neurosurgery, Toyooka Public Hospital.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Arai
authors.forename: Junji
authors.initials: J
authors.lastname: Koyama
authors.forename: Taichiro
authors.initials: T
authors.lastname: Imahori
authors.forename: Ryoji
authors.initials: R
authors.lastname: Shiomi
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Iwahashi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Eiji
authors.initials: E
authors.lastname: Kohmura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D020300:Intracranial Hemorrhages / Q000097:blood / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D055503:Protein Multimerization; D020521:Stroke / Q000097:blood / Q000209:etiology*; D020246:Venous Thrombosis / Q000097:blood / Q000150:complications*
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D