title: Laparoscopic gastric bypass versus laparoscopic sleeve gastrectomy: A retrospective multicenter comparison between early and long-term post-operative outcomes.
abstract: BACKGROUND
  Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are the most commonly performed procedures for morbid obesity.
  
  
  METHODS
  We performed a retrospective review of patients undergoing LRYGB or LSG between August 2000 and November 2014.
  
  
  RESULTS
  Data from 581 (280 LSG and 301 LRYGB) were gathered. Operating time (77.6 vs 250.5 min; p < 0.001), post-operative complication rate (3.9% vs 11.6%; p < 0.001), overall occlusions (p = 0.004), need for re-intervention (p < 0.001), hospital stay (5.7 vs 9.2 days; p < 0.001) and mean 1-year EWL (49% vs 61%; p = 0.001) resulted statistically significant lower in LSGs compared with LRYGBs. Not statistically significant differences were found about leakage, bleeding requiring transfusion, infections, short-term mortality and mean 2- and 3-years EWL. Upon univariate analysis, basal weight, basal BMI, age and gender were not associated with the rate of re-intervention and with the combination of re-intervention or death.
  
  
  CONCLUSIONS
  LRYGB resulted associated with higher post-operative morbidity rate and increased 1-year EWL than LSG. Prospective studies are needed to assess the impact of these two surgical procedures on the long-term weigh loss.
authors.affiliation: General Surgery, "San Giovanni Battista" Hospital, AUSL Umbria 2, Via M. Arcamone, 06034, Foligno, Italy; University of Perugia, Department of Surgical and Biomedical Sciences, Via G. Dottori, 06100, Perugia, Italy; General Surgery, "San Giovanni" Bellinzona e Valli Regional Hospital, 6500, Bellinzona, Switzerland.
authors.forename: Fabio
authors.initials: F
authors.lastname: Rondelli
authors.affiliation: General Surgery, "San Giovanni Battista" Hospital, AUSL Umbria 2, Via M. Arcamone, 06034, Foligno, Italy; PhD School of Biotechnologies, Department of Experimental Medicine, University of Perugia, Italy. Electronic address: walterbugiantella@alice.it.
authors.forename: Walter
authors.initials: W
authors.lastname: Bugiantella
authors.affiliation: University of Perugia, Department of Medicine, Internal and Cardiovascular Medicine and Stroke Unit, "Santa Maria della Misericordia" Hospital, Via G. Dottori, 06100, Perugia, Italy.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Vedovati
authors.affiliation: General Surgery, "San Giovanni Battista" Hospital, AUSL Umbria 2, Via M. Arcamone, 06034, Foligno, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Mariani
authors.affiliation: General Surgery, "San Giovanni" Bellinzona e Valli Regional Hospital, 6500, Bellinzona, Switzerland.
authors.forename: Ruben Carlo
authors.initials: RC
authors.lastname: Balzarotti Canger
authors.affiliation: General Surgery, "San Giovanni Battista" Hospital, AUSL Umbria 2, Via M. Arcamone, 06034, Foligno, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Federici
authors.affiliation: General Surgery, "San Giovanni" Bellinzona e Valli Regional Hospital, 6500, Bellinzona, Switzerland.
authors.forename: Adriano
authors.initials: A
authors.lastname: Guerra
authors.affiliation: General Surgery, "San Giovanni Battista" Hospital, AUSL Umbria 2, Via M. Arcamone, 06034, Foligno, Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Boni
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D012189:Retrospective Studies; D015431:Weight Loss; D055815:Young Adult
keywords: EWL; Gastric bypass; Laparoscopic; Obesity; Sleeve gastrectomy