title: A combined one-stage surgical approach of orbital tumor debulking, lid reconstruction, and ptosis repair in children with orbitotemporal neurofibromatosis.
abstract: OBJECTIVE
  To describe a series of children with neurofibromatosis type 1 (NF1) and a plexiform neurofibroma of the orbit with ptosis who underwent a combined one-stage surgery for tumor debulking, lid reconstruction, and ptosis repair.
  
  
  METHODS
  A retrospective review of 6 cases of combined one-step surgeries for orbital plexiform neurofibroma with ptosis.
  
  
  RESULTS
  The study included 6 children (4 boys, mean age 3.4 years). Follow-up time was at least 9 months. All children had unilateral orbitofacial plexiform. All children underwent a combined one-stage surgery performed by a single surgeon for tumor debulking, lid reconstruction, and ptosis repair. There was significant improvement in upper lid height and lid contour postoperatively in all the patients. One patient had early recurrence and underwent another two surgeries in the following years.
  
  
  CONCLUSIONS
  A combined surgical approach for orbital involvement in NF1 results in favorable immediate results, though late recurrence may require additional surgical interventions in the future.
authors.affiliation: Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: shaykeren88@gmail.com.
authors.forename: Shay
authors.initials: S
authors.lastname: Keren
authors.affiliation: Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Gad
authors.initials: G
authors.lastname: Dotan
authors.affiliation: Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Ran
authors.initials: R
authors.lastname: Ben-Cnaan
authors.affiliation: Department of Neonatology, Sheba Medical Center, Sackler Faculty of Medicine, Ramat Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Leah
authors.initials: L
authors.lastname: Leibovitch
authors.affiliation: Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Igal
authors.initials: I
authors.lastname: Leibovitch
mesh_terms: D019882:Blepharoplasty / Q000379:methods; D001763:Blepharoptosis / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D065426:Cytoreduction Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009456:Neurofibromatosis 1 / Q000601:surgery*; D009918:Orbital Neoplasms / Q000601:surgery*; D011182:Postoperative Care / Q000379:methods; D019651:Plastic Surgery Procedures / Q000379:methods; D012189:Retrospective Studies
keywords: Neurofibromatosis; Orbit; Plexiform; Ptosis; Surgery