title: Long-acting liposomal bupivacaine decreases inpatient narcotic requirements in men undergoing penile prosthesis implantation.
abstract: OBJECTIVE
  A new extended-release bupivacaine suspension bupivacaine (ERSB) delivers 3 days of local anesthetic and has been shown to reduce pain and narcotic usage in some patient groups but this issue is largely unstudied in urologic surgery.
  
  
  METHODS
  We performed a single-surgeon retrospective chart review of the patients who underwent penile prosthesis implantation. Pain scores and standardized morphine equivalent (ME) dose data were collected during 23 hour- observation period. Subjects who received ERSB were compared with those who received standard bupivacaine or no local anesthesia.
  
  
  RESULTS
  In a study population of 37 patients, those who received (n=13), and did not receive (n=24) ERSB were grouped, respectively. The groups were comparable demographically. ME was used 3.2 fold more frequently in the non-ERSB group (18.0, and 5.6 for non-ERSB, and ESRB groups, respectively (p=0.04). Mean overall pain scores were 3.8/10 for ERSB and 3.9/10 for non-ERSB group, respectively. Per patient medication cost for the control, and ERSB groups were $5.16 and $285.54, respectively.
  
  
  CONCLUSIONS
  The use of a new ERSB in penile prosthesis implants did lead to reduced narcotic consumption with comparable postoperative pain control to the non-ERSB group. However, the cost of the ERSB ($285/dose) may be prohibitive for its use.
authors.affiliation: Division of Urology, UC San Diego Health System, San Diego, California, USA.
authors.forename: Brittney H
authors.initials: BH
authors.lastname: Cotta
authors.affiliation: Division of Urology, Albany Medical Center, Albany, NY, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Welliver
authors.affiliation: Department of Radiology, Aurora St Luke Medical Center, Milwaukee, Wisconsin, USA.
authors.forename: Anand
authors.initials: A
authors.lastname: Brahmamdam
authors.affiliation: Division of Urology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Bednarchik
authors.affiliation: Division of Urology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
authors.forename: Danuta
authors.initials: D
authors.lastname: Dynda
authors.affiliation: Division of Urology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
authors.forename: Tobias S
authors.initials: TS
authors.lastname: Köhler
keywords: Erectile dysfunction; liposomal bupivacaine; local anesthetic; penile prosthesis