title: Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) - Report 1: Epidemiology and Classification.
abstract: OBJECTIVE
  To report the epidemiology and classification of ocular inflammation at a tertiary eye care center in Singapore.
  
  
  METHODS
  Retrospective cohort study of the clinical records of consecutive new cases from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database from 2004-2015.
  
  
  RESULTS
  A total of 2200 patients were studied from the OASIS database. The most common anatomic diagnosis was anterior uveitis (55.9%), posterior uveitis (17.5%), panuveitis (9.6%), and intermediate uveitis (4.7%). In addition, scleritis (6.1%), keratouveitis (2.8%), retinal vasculitis (2.2%), and episcleritis (1.2%) were observed. Etiology was established in 65.1%, with 35.2% of patients associated with non-infectious etiologies. The most common etiologies found were presumed tuberculosis (7.2%), followed by cytomegalovirus infection (6.9%), herpetic infection (6.3%), HLA-B27-associated anterior uveitis (4.2%), and ankylosing spondylitis (3.8%).
  
  
  CONCLUSIONS
  The pattern of ocular inflammation in Singapore has similarities with both Western and Asian populations. Anterior uveitis was the most common, with non-infectious etiologies being slightly more common than infectious etiologies.
authors.affiliation: a Yong Loo Lin School of Medicine , National University of Singapore , Singapore.
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Chen
authors.affiliation: b National Healthcare Group Eye Institute , Tan Tock Seng Hospital , Singapore.
authors.forename: Muhammad Amir
authors.initials: MA
authors.lastname: Bin Ismail
authors.affiliation: b National Healthcare Group Eye Institute , Tan Tock Seng Hospital , Singapore.
authors.forename: Helen
authors.initials: H
authors.lastname: Mi
authors.affiliation: b National Healthcare Group Eye Institute , Tan Tock Seng Hospital , Singapore.
authors.forename: Su Ling
authors.initials: SL
authors.lastname: Ho
authors.affiliation: b National Healthcare Group Eye Institute , Tan Tock Seng Hospital , Singapore.|c Eagle Eye Center , Mount Elizabeth Novena Hospital , Singapore.
authors.forename: Wee Kiak
authors.initials: WK
authors.lastname: Lim
authors.affiliation: b National Healthcare Group Eye Institute , Tan Tock Seng Hospital , Singapore.|c Eagle Eye Center , Mount Elizabeth Novena Hospital , Singapore.
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Teoh
authors.affiliation: a Yong Loo Lin School of Medicine , National University of Singapore , Singapore.|b National Healthcare Group Eye Institute , Tan Tock Seng Hospital , Singapore.
authors.forename: Rupesh
authors.initials: R
authors.lastname: Agrawal
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001327:Autoimmune Diseases / Q000145:classification / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D015817:Eye Infections / Q000145:classification / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D012189:Retrospective Studies; D017678:Sex Distribution; D012846:Singapore / Q000453:epidemiology; D062606:Tertiary Care Centers; D014605:Uveitis / Q000145:classification / Q000453:epidemiology*; D055815:Young Adult
keywords: Classification; OASIS; epidemiology; ocular inflammation; uveitis