title: [Effects of infant feeding practice on eczema during early childhood in Shanghai, Hohhot, and Fuzhou].
abstract: Objective:To estimate the prevalence of eczema in early childhood and effect of infant feeding practice on eczema by different regions of China with diverse climate and dietary patterns.Method:A questionnaire survey was conducted from June 2012 to October 2012 in Shanghai, Hohhot, and Fuzhou. The parent or guardian of the children aged between 2.5 to 3.5 years attending routine health visit in the chosen communities were invited to complete a modified questionnaire of the International Study of Asthma and Allergy in Childhood (ISAAC). Logistic regression model was used to analyze of the family history of allergy, duration of breastfeeding, timing of introduction of complementary foods and other potential confounders.Result:A total of 2 242 children were interviewed, 750 from Shanghai, 716 from Hohhot, and 776 from Fuzhou. The prevalence of eczema in early childhood was significantly different among Shanghai (16.9%, 95%CI16.87-16.93), Hohhot (34.5%, 95%CI34.46-34.54)and Fuzhou (44.3%, 95%CI44.26-44.34). The difference was statistically significant between 3 groups (χ2=72.05,P<0.05). Introducing complementary food after the age of 6 months was associated with a decreased risk for eczema when compared to introduction between 4 to 6 months(odds ratio (OR) 0.58, 95%CI0.41-0.81) in Fuzhou, while there was no significant association between timing of introduction of complementary foods and eczema in Shanghai and Hohhot.Conclusion:The prevalence of eczema during early childhood is various among three cities. The relationship between timing of introduction of complementary foods and eczema in Fuzhou is different from that in Shanghai and Hohhot. The role of climate and dietary patterns on prevalence of eczema needs further studies.
authors.affiliation: Department of Primary Child Health Care, Children's Hospital of Fudan University, Shanghai 201102, China.
authors.forename: X Q
authors.initials: XQ
authors.lastname: Zheng
authors.forename: G W
authors.initials: GW
authors.lastname: Zhu
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Zheng
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: C D
authors.initials: CD
authors.lastname: Gong
authors.forename: S S
authors.initials: SS
authors.lastname: Deng
authors.forename: Q L
authors.initials: QL
authors.lastname: Wu
authors.forename: Y M
authors.initials: YM
authors.lastname: Peng
mesh_terms: D001249:Asthma / Q000453:epidemiology / Q000209:etiology; D001942:Breast Feeding; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004485:Eczema / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology* / Q000208:ethnology; D007223:Infant; D007225:Infant Food; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population; D011795:Surveys and Questionnaires; D014505:Urban Population