title: Metal-Free Photoredox Catalyzed Cyclization of O-(2,4-Dinitrophenyl)oximes to Phenanthridines.
abstract: A metal-free visible-light photoredox-catalyzed intermolecular cyclization reaction ofO-2,4-dinitrophenyl oximes to phenanthridines was developed. In this study, the organic dye eosin Y andi-Pr₂NEt were used as photocatalyst and terminal reductant, respectively. The oxime substrates were transformed into iminyl radical intermediates by single-electron reduction, which then underwent intermolecular homolytic aromatic substitution (HAS) reactions to give phenanthridine derivatives.
authors.affiliation: National and Provincial Union Engineering Research Center for the Veterinary Herbal Medicine Resources and Initiative, Hunan Agricultural University, Changsha 410128, China. Xiubin_liu@163.com.|Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan Agricultural University, Changsha 410128, China. Xiubin_liu@163.com.
authors.forename: Xiubin
authors.initials: X
authors.lastname: Liu
authors.affiliation: National and Provincial Union Engineering Research Center for the Veterinary Herbal Medicine Resources and Initiative, Hunan Agricultural University, Changsha 410128, China. zxqing1219@sina.com.|Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan Agricultural University, Changsha 410128, China. zxqing1219@sina.com.
authors.forename: Zhixing
authors.initials: Z
authors.lastname: Qing
authors.affiliation: National and Provincial Union Engineering Research Center for the Veterinary Herbal Medicine Resources and Initiative, Hunan Agricultural University, Changsha 410128, China. picheng55@126.com.|Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan Agricultural University, Changsha 410128, China. picheng55@126.com.
authors.forename: Pi
authors.initials: P
authors.lastname: Cheng
authors.affiliation: National and Provincial Union Engineering Research Center for the Veterinary Herbal Medicine Resources and Initiative, Hunan Agricultural University, Changsha 410128, China. xinyuzazy@outlook.com.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Zheng
authors.affiliation: National and Provincial Union Engineering Research Center for the Veterinary Herbal Medicine Resources and Initiative, Hunan Agricultural University, Changsha 410128, China. ginkgo@world-way.net.|Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan Agricultural University, Changsha 410128, China. ginkgo@world-way.net.
authors.forename: Jianguo
authors.initials: J
authors.lastname: Zeng
authors.affiliation: National and Provincial Union Engineering Research Center for the Veterinary Herbal Medicine Resources and Initiative, Hunan Agricultural University, Changsha 410128, China. xiehongqi2006@126.com.|Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan Agricultural University, Changsha 410128, China. xiehongqi2006@126.com.
authors.forename: Hongqi
authors.initials: H
authors.lastname: Xie
mesh_terms: D002384:Catalysis; D003500:Cyclization; D010084:Oxidation-Reduction; D010091:Oximes / Q000737:chemistry*; D010617:Phenanthridines / Q000737:chemistry*; D055668:Photochemical Processes; D066244:Proton Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D010091:Oximes; D010617:Phenanthridines
keywords: O-aryl oximes; eosin Y; phenanthridines; photoredox catalysis; visible light