title: Retromer Sets a Trap for Endosomal Cargo Sorting.
abstract: Membrane trafficking from endosomes to the trans-Golgi network or the plasma membrane is driven by the retromer complex. Through structural analysis of the cargo-bound complex, Lucas et al. describe a mechanism by which endosomal membrane recruitment and cargo recognition are integrated through cooperative interactions between retromer subunits.
authors.affiliation: Institut Curie, PSL Research University, Chemical Biology of Membranes and Therapeutic Delivery unit, INSERM U 1143, CNRS UMR 3666, 26 rue d'Ulm, 75248 Paris Cedex 05, France. Electronic address: ludger.johannes@curie.fr.
authors.forename: Ludger
authors.initials: L
authors.lastname: Johannes
authors.affiliation: Institut Curie, PSL Research University, Chemical Biology of Membranes and Therapeutic Delivery unit, INSERM U 1143, CNRS UMR 3666, 26 rue d'Ulm, 75248 Paris Cedex 05, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Wunder
mesh_terms: D002462:Cell Membrane / Q000378:metabolism; D011992:Endosomes / Q000378:metabolism*; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism; D021381:Protein Transport; D033921:Vesicular Transport Proteins / Q000737:chemistry; D021601:trans-Golgi Network / Q000378:metabolism*
chemical_list: D033921:Vesicular Transport Proteins