title: Pregnancy and cirrhosis: four cases at the Lome campus university teaching hospital (Togo).
abstract: To evaluate the hepatic and obstetric complications in pregnant women with cirrhosis. We report the cases of four pregnant women with cirrhosis treated in the gastroenterology and obstetrics-gynecology departments of the Lome Campus University Teaching Hospital between 2013 and 2015. The women's mean age was 32 years. Three were in the first trimester of pregnancy. Almost all had signs of advanced cirrhosis, including ascites (50%), lower-limb edema (75%), and jaundice (25%). All (100%) had liver failure and anemia. Cirrhosis was due to hepatitis virus B infection for 3 women. All had singleton pregnancies. Two mothers died; fetal outcome included one fetal loss and one stillbirth. This study shows the high risk associated with the combination of pregnancy and cirrhosis. Prognosis is poor for both mother and fetus.
authors.affiliation: Service d'hépato-gastro-entérologie, CHU Campus de Lomé, 15BP110 Lomé, Togo.
authors.forename: A
authors.initials: A
authors.lastname: Bagny
authors.affiliation: CHU Sylvanus Olympio, Lomé, Togo.
authors.forename: D A E
authors.initials: DA
authors.lastname: Akolly
authors.affiliation: CHU Campus de Lomé, Lomé, Togo.
authors.forename: L M
authors.initials: LM
authors.lastname: Lawson-Ananisoh
authors.affiliation: CHU Campus de Lomé, Lomé, Togo.
authors.forename: O
authors.initials: O
authors.lastname: Bouglouga
authors.affiliation: CHU Sylvanus Olympio, Lomé, Togo.
authors.forename: B
authors.initials: B
authors.lastname: Douaguibe
authors.affiliation: CHU Campus de Lomé, Lomé, Togo.
authors.forename: R
authors.initials: R
authors.lastname: El Hadji Yacoubou
authors.affiliation: CHU Sylvanus Olympio, Lomé, Togo.
authors.forename: S
authors.initials: S
authors.lastname: Koffi
authors.affiliation: CHU Sylvanus Olympio, Lomé, Togo.
authors.forename: K
authors.initials: K
authors.lastname: Lawson Evi
authors.affiliation: CHU Sylvanus Olympio, Lomé, Togo.
authors.forename: K M
authors.initials: KM
authors.lastname: Guedenon
authors.affiliation: CHU Sylvanus Olympio, Lomé, Togo.
authors.forename: Y D
authors.initials: YD
authors.lastname: Atakouma
authors.affiliation: CHU Sylvanus Olympio, Lomé, Togo.
authors.forename: K
authors.initials: K
authors.lastname: Akpadza
authors.affiliation: CHU Campus de Lomé, Lomé, Togo.
authors.forename: D
authors.initials: D
authors.lastname: Redah
mesh_terms: D000328:Adult; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis; D014037:Togo; D014495:Universities
keywords: Lome; Togo; cirrhosis; outcome; pregnancy; viral hepatitis