title: Review: Surveillance of patients with Barrett oesophagus.
abstract: There has been a rapid increase in the incidence of oesophageal adenocarcinoma in most Western countries over the past thirty years. Barrett's oesophagus (BE) is a common premalignant lesion of oesophageal adenocarcinoma, although the risk of developing cancer in BE remains low. Therefore, screening is not recommended in the general population. Surveillance of BE is recommended to detect high grade dysplasia or carcinoma in an early stage, although there is no clear evidence that surveillance leads to a reduced mortality. This review discusses the several screening and surveillance techniques, including chromoendoscopy, narrow band imaging, autofluorescence imaging and confocal laser endomicroscopy, pointing out the areas that are well established as well as the new techniques that require more research.
authors.affiliation: Catholic University of Leuven (KUL), University Hospitals Leuven, Department of Gastroenterology and Hepatology, Herestraat 49, 3000 Leuven, Belgium. Electronic address: sielte.maes@student.kuleuven.be.
authors.forename: Sielte
authors.initials: S
authors.lastname: Maes
authors.affiliation: University of Kansas School of Medicine and Veterans Affairs Medical Center, Kansas City, USA. Electronic address: psharma@kumc.edu.
authors.forename: Prateek
authors.initials: P
authors.lastname: Sharma
authors.affiliation: Catholic University of Leuven (KUL), TARGID, University Hospitals Leuven, Department of Gastroenterology and Hepatology, Herestraat 49, 3000 Leuven, Belgium. Electronic address: raf.bisschops@uzleuven.be.
authors.forename: Raf
authors.initials: R
authors.lastname: Bisschops
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D001471:Barrett Esophagus / Q000175:diagnosis*; D014408:Biomarkers, Tumor / Q000378:metabolism; D003938:Diagnostic Techniques, Digestive System; D004938:Esophageal Neoplasms / Q000175:diagnosis; D006801:Humans; D008403:Mass Screening / Q000379:methods; D062048:Narrow Band Imaging / Q000379:methods; D061848:Optical Imaging / Q000379:methods; D011159:Population Surveillance; D011230:Precancerous Conditions / Q000175:diagnosis
chemical_list: D014408:Biomarkers, Tumor
keywords: Advanced imaging techniques; Autofluorescence imaging; Barrett's oesophagus; Biomarkers; Confocal endomicroscopy; Cytology; Dysplasia; ETMI; Narrow band imaging; Oesophageal adenocarcinoma; Screening; Surveillance