title: Genotype distribution and allele frequencies of the genes associated with body composition and locomotion traits in Myanmar native horses.
abstract: Myanmar native horses are small horses used mainly for drafting carts or carriages in rural areas and packing loads in mountainy areas. In the present study, we investigated genotype distributions and allele frequencies of the LCORL/NCAPG, MSTN and DMRT3 genes, which are associated with body composition and locomotion traits of horses, in seven local populations of Myanmar native horses. The genotyping result of LCORL/NCAPG showed that allele frequencies of C allele associated with higher withers height ranged from 0.08 to 0.27, and 0.13 in average. For MSTN, allele frequencies of C allele associated with higher proportion of Type 2B muscular fiber ranged from 0.05 to 0.23, and 0.09 in average. For DMRT3, allele frequencies of A allele associated with ambling gait ranged from 0 to 0.04, and 0.01 in average. The presences of the minor alleles of these genes at low frequencies suggest a possibility that these horse populations have not been under strong selection pressure for particular locomotion traits and body composition. Our findings of the presence of these minor alleles in Southeast Asian native horses are also informative for considering the origins of these minor alleles associated with body composition and locomotion traits in horse populations.
authors.affiliation: Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan.
authors.forename: Yu
authors.initials: Y
authors.lastname: Okuda
authors.affiliation: University of Veterinary Science, Nay Pyi Taw, Myanmar.
authors.forename: Hla Hla
authors.initials: HH
authors.lastname: Moe
authors.affiliation: University of Veterinary Science, Nay Pyi Taw, Myanmar.
authors.forename: Kyaw Kyaw
authors.initials: KK
authors.lastname: Moe
authors.affiliation: Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Shimizu
authors.affiliation: Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Nishioka
authors.affiliation: Faculty of Agriculture, Kagoshima University, Kagoshima, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shimogiri
authors.affiliation: Graduate School of Agricultural Science, Kobe University, Kobe, Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Mannen
authors.affiliation: Institute of Animal Science, Aichi, Japan.
authors.forename: Misao
authors.initials: M
authors.lastname: Kanemaki
authors.affiliation: Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Kunieda
mesh_terms: D000818:Animals; D001823:Body Composition / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics*; D056726:Genetic Association Studies / Q000662:veterinary*; D005838:Genotype; D006736:Horses / Q000235:genetics* / Q000502:physiology*; D008124:Locomotion / Q000235:genetics*; D002052:Myanmar
keywords: DMRT3; LCORL/NCAPG; MSTN; Myanmar native horses; allele frequency