title: Preparation of a Bis-GMA-Free Dental Resin System with Synthesized Fluorinated Dimethacrylate Monomers.
abstract: With the aim of reducing human exposure to Bisphenol A (BPA) derivatives in dentistry, a fluorinated dimethacrylate monomer was synthesized to replace 2,2-bis[4-(2-hydroxy-3-methacryloy-loxypropyl)-phenyl]propane (Bis-GMA) as the base monomer of dental resin. After mixing with reactive diluent triethyleneglycol dimethacrylate (TEGDMA), fluorinated dimethacrylate (FDMA)/TEGDMA was prepared and compared with Bis-GMA/TEGDMA in physicochemical properties, such as double bond conversion (DC), volumetric shrinkage (VS), water sorption (WS) and solubility (WSL), flexural strength (FS) and modulus (FM). The results showed that, when compared with Bis-GMA based resin, FDMA-based resin had several advantages, such as higher DC, lower VS, lower WS, and higher FS after water immersion. All of these revealed that FDMA had potential to be used as a substitute for Bis-GMA. Of course, many more studies, such as biocompatibility testing, should be undertaken to prove whether FDMA could be applied in clinic.
authors.affiliation: College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China. top_silly@sina.cn.
authors.forename: Shuzhen
authors.initials: S
authors.lastname: Luo
authors.affiliation: College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China. zhu_wb@outlook.com.
authors.forename: Wenbin
authors.initials: W
authors.lastname: Zhu
authors.affiliation: College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China. msfliu@126.com.
authors.forename: Fang
authors.initials: F
authors.lastname: Liu
authors.affiliation: College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China. msjwhe@scut.edu.cn.
authors.forename: Jingwei
authors.initials: J
authors.lastname: He
mesh_terms: D001559:Benzhydryl Compounds / Q000737:chemistry / Q000627:therapeutic use; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D003188:Composite Resins / Q000138:chemical synthesis / Q000737:chemistry; D003764:Dental Materials / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D054879:Halogenation; D006801:Humans; D010636:Phenols / Q000737:chemistry / Q000627:therapeutic use; D011092:Polyethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D011109:Polymethacrylic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D012117:Resins, Synthetic / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D012995:Solubility; D014867:Water / Q000737:chemistry; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D001672:Biocompatible Materials; D003188:Composite Resins; D003764:Dental Materials; D010636:Phenols; D011092:Polyethylene Glycols; D011109:Polymethacrylic Acids; D012117:Resins, Synthetic; D014867:Water; C020946:triethylene glycol dimethacrylate; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Bis-GMA free; dental resin; fluorinated dimethacrylate; physicochemical properties