title: Treatment of Radiation-Induced Urethral Strictures.
abstract: Radiation therapy may result in urethral strictures from vascular damage. Most radiation-induced urethral strictures occur in the bulbomembranous junction, and urinary incontinence may result as a consequence of treatment. Radiation therapy may compromise reconstruction due to poor tissue healing and radionecrosis. Excision and primary anastomosis is the preferred urethroplasty technique for radiation-induced urethral stricture. Principles of posterior urethroplasty for trauma may be applied to the treatment of radiation-induced urethral strictures. Chronic management with suprapubic tube is an option based on patient comorbidities and preference.
authors.affiliation: Department of Urology, University of Texas Southwestern, Dallas, TX, USA.
authors.forename: Matthias D
authors.initials: MD
authors.lastname: Hofer
authors.affiliation: Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
authors.forename: Joceline S
authors.initials: JS
authors.lastname: Liu
authors.affiliation: Department of Urology, University of Texas Southwestern, Dallas, TX, USA. Electronic address: allen.morey@utsouthwestern.edu.
authors.forename: Allen F
authors.initials: AF
authors.lastname: Morey
mesh_terms: D000714:Anastomosis, Surgical; D006801:Humans; D008297:Male; D011832:Radiation Injuries / Q000150:complications* / Q000601:surgery; D016896:Treatment Outcome; D014521:Urethra / Q000528:radiation effects / Q000601:surgery*; D014525:Urethral Stricture / Q000209:etiology / Q000601:surgery*; D013521:Urologic Surgical Procedures, Male / Q000379:methods*
keywords: Prostate cancer; Radiation therapy; Urethroplasty