title: Pediatric Sepsis.
abstract: Pediatric sepsis is distinct from adult sepsis in its definitions, clinical presentations, and management. Recognition of pediatric sepsis is complicated by the various pediatric-specific comorbidities that contribute to its mortality and the age- and development-specific vital sign and clinical parameters that obscure its recognition. This article outlines the clinical presentation and management of sepsis in neonates, infants, and children, and highlights some key populations who require specialized care.
authors.affiliation: Departments of Emergency Medicine and Pediatrics, Virginia Tech Carilion School of Medicine, 1 Riverside Circle, Roanoke, VA 24016, USA. Electronic address: mkprusakowski@carilionclinic.org.
authors.forename: Melanie K
authors.initials: MK
authors.lastname: Prusakowski
authors.affiliation: Department of Emergency Medicine, Carilion Clinic, 1 Riverside Circle, Roanoke, VA 24016, USA.
authors.forename: Audrey P
authors.initials: AP
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004636:Emergency Service, Hospital; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000628:therapy; D018805:Sepsis / Q000175:diagnosis* / Q000628:therapy
keywords: Goal-directed therapy; Multi-system organ failure; Neonatal sepsis; Pediatric sepsis