title: Data on genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice.
abstract: The data presented here are related to the research article, entitled Genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice, published in Atherosclerosis 2016;254:124 (A.T. Grainger, M.B. Jones, J. Li, M.H. Chen, A. Manichaikul, W. Shi, 2016) [1]. The supporting materials include original genotypic and phenotypic data obtained from 206 female F2 mice derived from an intercross between BALB and SMJ inbred mice. The F2 mice were fed 12 weeks of Western diet, starting at 6 weeks of age. Atherosclerotic lesion size in the aortic root of each mouse is the sum of the top 8 lesion areas. The data is provided in the format required for determining QTLs using two independent programs, J/QTL and PLINK.
authors.affiliation: Departments of Biochemistry & Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Grainger
authors.affiliation: Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
authors.forename: Michael B
authors.initials: MB
authors.lastname: Jones
authors.affiliation: Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
authors.forename: Mei-Hua
authors.initials: MH
authors.lastname: Chen
authors.affiliation: Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.
authors.forename: Ani
authors.initials: A
authors.lastname: Manichaikul
authors.affiliation: Departments of Biochemistry & Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA; Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
authors.forename: Weibin
authors.initials: W
authors.lastname: Shi
keywords: Atherosclerosis; Major histocompatibility complex; Mice; Quantitative trait locus