title: Control of scarring: critique II.
abstract: It Is now widely known that wounds Inflicted in utero on the fetus of some mammalian species can heal without scarring. This has potential in the management of wounds in adults, the result being that there could be complete restoration of tissue integrity with no cosmetic disfigurement. The normal response to trauma Involves a complicated acute inflammatory response mediated mainly through the macrophage and cytokine cascades. This has become established through our evolution and it is not known what may result from interference using genetically engineered manipulations or addition of factors which promote or inhibit stages of the inflammatory response.
authors.affiliation: Professor of surgery, University of Newcastle, North Tees Hospital, Stockton-on-Tees.
authors.forename: D J
authors.initials: DJ
authors.lastname: Leaper