title: Dental implant loss in older versus younger patients: a systematic review and meta-analysis of prospective studies.
abstract: The aim of this systematic review was to evaluate implant loss in younger and older patients. An electronic search of four databases (MEDLINE, EMBASE, SCOPUS and the Cochrane Library) was undertaken until May 2016 without time restriction and was supplemented by manual searching. Prospective cohorts were included if they met the following criteria: (i) presence of an exposed group (older subjects) with a minimum age of 60 years; (ii) presence of a control group (younger subjects) with a maximum age of 59 years; and (iii) outcome data considering implant survival or loss. Meta-analyses were performed to evaluate the impact of ageing on implant failure. Of 4152 potentially eligible articles, four were included in the qualitative analysis and quantitative synthesis. The pooled estimates suggest that the risk of implant loss in older patients is not significantly higher (RR = 0·92; 95% CI 0·43-1·96, P = 0·83) when compared to younger subjects. This systematic review suggests that age is not a limiting factor for dental implant therapy.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Odontology, University of São Paulo, São Paulo, Brazil.
authors.forename: D I
authors.initials: DI
authors.lastname: Sendyk
authors.affiliation: Division of Periodontics, Department of Stomatology, Faculty of Odontology, University of São Paulo, São Paulo, Brazil.
authors.forename: E S
authors.initials: ES
authors.lastname: Rovai
authors.affiliation: Division of Periodontics, Department of Stomatology, Faculty of Odontology, University of São Paulo, São Paulo, Brazil.
authors.forename: C M
authors.initials: CM
authors.lastname: Pannuti
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Odontology, University of São Paulo, São Paulo, Brazil.
authors.forename: M C Z
authors.initials: MC
authors.lastname: Deboni
authors.affiliation: Department of Periodontology and Implantology, Faculty of Odontology, University of Santo Amaro, São Paulo, Brazil.
authors.forename: W R
authors.initials: WR
authors.lastname: Sendyk
authors.affiliation: Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Wennerberg
mesh_terms: D000367:Age Factors; D003758:Dental Implantation, Endosseous / Q000009:adverse effects / Q000379:methods*; D015921:Dental Implants; D019232:Dental Restoration Failure / Q000706:statistics & numerical data*; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000601:surgery*; D011446:Prospective Studies
chemical_list: D015921:Dental Implants
keywords: aged patient; dental implants; implant failure; implant loss; older adults; osseointegration