title: Could High Volume of Physical Activities in Early Pregnancy Interfere with Deep Placentation?
abstract: BackgroundThe impact of physical activity (PA) during pregnancy on obstetrical outcomes remains controversial. We followed pregnant women who reported more than 3 hours of sustained PA per week during the first trimester of pregnancy.CasesTotal five eligible women were followed. We observed small placenta from the first trimester (median: 0.68; interquartile [IQ]: 0.62-0.97 multiples of median [MoM]) to delivery (median: 0.82; IQ: 0.71-0.94 MoM), high uterine artery pulsatility index in the first (median: 1.82; IQ: 1.68-1.99 MoM) and second trimesters (median: 1.33; IQ: 1.11-1.56 MoM) of pregnancy. Placenta pathology revealed deep vasculopathy in three (60%) cases. However, all participants delivered at term and none of them experienced preeclampsia.ConclusionThis small case series suggest that high PA volume in first trimester could interfere with deep placentation.
authors.affiliation: Department of Obstetrics and Gynecology, Université Laval, Québec City, Quebec, Canada.
authors.forename: Chantale
authors.initials: C
authors.lastname: Vachon-Marceau
authors.affiliation: Centre de recherche du CHU de Québec, Mother, Child and Reproductive Health, Université Laval, Quebec City, Quebec, Canada.
authors.forename: Mario
authors.initials: M
authors.lastname: Girard
authors.affiliation: Centre de recherche du CHU de Québec, Mother, Child and Reproductive Health, Université Laval, Quebec City, Quebec, Canada; Department of Kinesiology, Université Laval, Québec City, Quebec, Canada.
authors.forename: Michèle
authors.initials: M
authors.lastname: Bisson
authors.affiliation: Department of Obstetrics and Gynecology, Université Laval, Québec City, Quebec, Canada.
authors.forename: Suzanne
authors.initials: S
authors.lastname: Demers
authors.affiliation: Centre de recherche du CHU de Québec, Mother, Child and Reproductive Health, Université Laval, Quebec City, Quebec, Canada; Department of Pediatrics, Université Laval, Québec City, Quebec, Canada.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Marc
authors.affiliation: Department of Obstetrics and Gynecology, Université Laval, Québec City, Quebec, Canada; Centre de recherche du CHU de Québec, Mother, Child and Reproductive Health, Université Laval, Quebec City, Quebec, Canada.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Bujold
keywords: biomarker; physical activity; placenta; preeclampsia; pregnancy; ultrasound