title: Postnatal outcome and placental blood flow after plasmapheresis during pregnancy.
abstract: OBJECTIVE
  Plasmapheresis in pregnancy adversely affects maternal hemodynamics, however there are studies suggesting it to reduce pregnancy loss in immunological diseases when medication is more harmful to the fetus. The overall optimal plasmapheresis treatment protocol remains unknown.
  
  
  METHODS
  A pregnant with neuromyelitis optica was followed up after receiving six volumes of fresh frozen plasma via plasmapheresis.
  
  
  RESULTS
  The placenta compensated the hemodynamic change until the 33rd week of gestation, resulting a small for gestational age, otherwise healthy girl.
  
  
  CONCLUSIONS
  More research is needed on plasma exchange during pregnancy because in our observation placental circulation can adapt to the change in blood pressure.
authors.affiliation: a Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary.
authors.forename: Mária
authors.identifier: http://orcid/org/0000-0002-3471-0428
authors.initials: M
authors.lastname: Jakó
authors.affiliation: a Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary.
authors.forename: Andrea
authors.identifier: http://orcid/org/0000-0002-1168-7261
authors.initials: A
authors.lastname: Surányi
authors.affiliation: b Department of Ophthalmology , University of Szeged , Szeged , Hungary.
authors.forename: Márta
authors.initials: M
authors.lastname: Janáky
authors.affiliation: c Department of Neurology , University of Szeged , Szeged , Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Klivényi
authors.affiliation: d Department of Pathology , University of Szeged , Szeged , Hungary.
authors.forename: László
authors.initials: L
authors.lastname: Kaizer
authors.affiliation: c Department of Neurology , University of Szeged , Szeged , Hungary.
authors.forename: László
authors.initials: L
authors.lastname: Vécsei
authors.affiliation: a Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary.
authors.forename: György
authors.initials: G
authors.lastname: Bártfai
authors.affiliation: a Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary.
authors.forename: Gábor
authors.identifier: http://orcid/org/0000-0003-1829-3457
authors.initials: G
authors.lastname: Németh
mesh_terms: D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D009471:Neuromyelitis Optica / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D010920:Placenta / Q000098:blood supply*; D021041:Placental Circulation; D010956:Plasmapheresis / Q000379:methods; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome
keywords: Plasmapheresis; intrauterine growth restriction; neuromyelitis optica; placental vascularization