title: Defining and Diagnosing Sepsis.
abstract: Sepsis is a heterogeneous clinical syndrome that encompasses infections of many different types and severity. Not surprisingly, it has confounded most attempts to apply a single definition, which has also limited the ability to develop a set of reliable diagnostic criteria. It is perhaps best defined as the different clinical syndromes produced by an immune response to infection that causes harm to the body beyond that of the local effects of the infection.
authors.affiliation: Adult Intensive Care Unit, Saint Agnes Hospital, 900 S. Caton Ave, Baltimore, MD 21229, USA. Electronic address: mikescott@umem.org.
authors.forename: Michael C
authors.initials: MC
authors.lastname: Scott
mesh_terms: D006801:Humans; D063305:Organ Dysfunction Scores; D064872:Patient Care Bundles / Q000592:standards; D018805:Sepsis / Q000175:diagnosis* / Q000473:pathology; D012772:Shock, Septic / Q000175:diagnosis / Q000473:pathology; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis / Q000473:pathology
keywords: SOFA; Sepsis; Septic shock; Severe sepsis; qSOFA