title: Regio- and Chemoselective Mono- and Bisnitration of 8-Amino quinoline Amides with Fe(NO3)3·9H2O as Promoter and Nitro Source.
abstract: An efficient and regioselective remote C(5)-H nitration of 8-aminoquinoline amides by using the economical and nontoxic Fe(NO3)3·9H2O as promoter and nitro source has been developed. Furthermore, when CuCl2·2H2O was used as a catalyst, 8-aminoquinoline amides dominantly underwent bisnitration to give 5,7-dinitro-8-aminoquinoline amides. Notably, this is the first example in which Fe(NO3)3·9H2O plays a dual role as both chelating promoter and nitration reagent, and CuCl2·2H2O acts as an efficient catalyst for the bisnitration of quinolines.
authors.affiliation: Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, School of Environment, Henan Normal University , Xinxiang, Henan 453007, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.affiliation: Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, School of Environment, Henan Normal University , Xinxiang, Henan 453007, China.
authors.forename: Ningning
authors.initials: N
authors.lastname: Zhao
authors.affiliation: Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, School of Environment, Henan Normal University , Xinxiang, Henan 453007, China.
authors.forename: Liqi
authors.initials: L
authors.lastname: Qiu
authors.affiliation: Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, School of Environment, Henan Normal University , Xinxiang, Henan 453007, China.
authors.forename: Xinying
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, School of Environment, Henan Normal University , Xinxiang, Henan 453007, China.
authors.forename: Xuesen
authors.initials: X
authors.lastname: Fan