title: FDG PET/MR in initial staging of sarcoma: Initial experience and comparison with conventional imaging.
abstract: OBJECTIVE
  To assess the feasibility of positron emission tomography/magnetic resonance imaging (PET/MR) with 18F-fluordeoxyglucose (FDG) for initial staging of sarcoma.
  
  
  METHODS
  Twenty-nine patients with sarcoma were included in this study. Weighted kappa (κ) was used to assess the agreement between PET/MR and conventional imaging (CT and MR). The accuracy of PET/MR and conventional imaging for distant metastases was compared using receiver operating characteristic (ROC) analysis.
  
  
  RESULTS
  T and M stage were identical for PET/MR and conventional modalities in all patients (κ=1). N stage was identical for 28/29 patients (κ=0.65).
  
  
  CONCLUSIONS
  FDG PET/MR shows excellent agreement with the currently preferred imaging methods (CT and MR) in initial staging of sarcoma.
authors.affiliation: Dresden University Hospital, Department of Radiology, Fetscherstr. 74, 01307 Dresden, Germany. Electronic address: ivan.platzek@uniklinikum-dresden.de.
authors.forename: Ivan
authors.initials: I
authors.lastname: Platzek
authors.affiliation: Dresden University Hospital, Department of Nuclear Medicine, Fetscherstr. 74, 01307 Dresden, Germany.
authors.forename: Bettina
authors.initials: B
authors.lastname: Beuthien-Baumann
authors.affiliation: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstr. 400, 01328 Dresden, Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Schramm
authors.affiliation: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstr. 400, 01328 Dresden, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Maus
authors.affiliation: Dresden University Hospital, Department of Radiology, Fetscherstr. 74, 01307 Dresden, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Laniado
authors.affiliation: Dresden University Hospital, Department of Nuclear Medicine, Fetscherstr. 74, 01307 Dresden, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: Kotzerke
authors.affiliation: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstr. 400, 01328 Dresden, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: van den Hoff
authors.affiliation: Dresden University Hospital, Department of Internal Medicine, Fetscherstr. 74, 01307 Dresden, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Schuler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods*; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D012509:Sarcoma / Q000000981:diagnostic imaging* / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: PET/MR; Sarcoma; Staging