title: Early response does not predict outcome in children and adolescents with chronic myeloid leukaemia treated with high-dose imatinib.
authors.affiliation: Haematology, Department of Cellular Biotechnologies and Haematology, Sapienza University, Rome, Italy.
authors.forename: Fiorina
authors.initials: F
authors.lastname: Giona
authors.affiliation: Department of Clinical and Biological Sciences, University of Turin at Orbassano, Turin, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Saglio
authors.affiliation: Haematology, Department of Cellular Biotechnologies and Haematology, Sapienza University, Rome, Italy.
authors.forename: Michelina
authors.initials: M
authors.lastname: Santopietro
authors.affiliation: Paediatric Haematology Unit, Santobono-Pausilipon Hospital, Naples, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Menna
authors.affiliation: Department of Women's and Children's Health,  Padova University Hospital, Padua, Italy.
authors.forename: Maria Caterina
authors.initials: MC
authors.lastname: Putti
authors.affiliation: Clinical Experimental Haematology Unit, Gaslini Research Institute, Genoa, Italy.
authors.forename: Concetta
authors.initials: C
authors.lastname: Micalizzi
authors.affiliation: Division of Haematology, Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy.
authors.forename: Grazia
authors.initials: G
authors.lastname: Iaria
authors.affiliation: U.O. di Oncologia ed Ematologia Oncologica Pediatrica, Policlinico, Bari, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Santoro
authors.affiliation: Department of Paediatrics, "Casa Sollievo della Sofferenza" Hospital, San Giovanni Rotondo, Italy.
authors.forename: Saverio
authors.initials: S
authors.lastname: Ladogana
authors.affiliation: Paediatric Haemato-Oncology Unit, Ospedale Regionale per le Microcitemie, Cagliari, Italy.
authors.forename: Rosamaria
authors.initials: R
authors.lastname: Mura
authors.affiliation: Department of Reproduction and Growth, University Hospital Sant'Anna in Ferrara, Ferrara, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Burnelli
authors.affiliation: Haemato-Oncology Unit, Azienda Ospedaliera "Pugliese-Ciaccio", Catanzaro, Italy.
authors.forename: Caterina
authors.initials: C
authors.lastname: Consarino
authors.affiliation: Paediatric Unit, Ospedale di Sassari, Sassari, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Cosmi
authors.affiliation: Haematology, Department of Cellular Biotechnologies and Haematology, Sapienza University, Rome, Italy.
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Moleti
authors.affiliation: Clinical Experimental Haematology Unit, Gaslini Research Institute, Genoa, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Leszl
authors.affiliation: Paediatric Haematology Unit, Santobono-Pausilipon Hospital, Naples, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Tucci
authors.affiliation: Haematology, Department of Cellular Biotechnologies and Haematology, Sapienza University, Rome, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Nanni
authors.affiliation: Haematology, Department of Cellular Biotechnologies and Haematology, Sapienza University, Rome, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Diverio
authors.affiliation: Department of Paediatrics, University of Milano-Bicocca, Monza, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Biondi
authors.affiliation: Dipartimento di Oncoematologia Pediatrica, IRCCS Ospedale Bambino Gesù, Rome, Italy.|Dipartimento di Scienze Pediatriche Università di Pavia, Italy.
authors.forename: Franco
authors.initials: F
authors.lastname: Locatelli
authors.affiliation: Haematology, Department of Cellular Biotechnologies and Haematology, Sapienza University, Rome, Italy.
authors.forename: Robin
authors.initials: R
authors.lastname: Foà
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D000068877:Imatinib Mesylate / Q000008:administration & dosage*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000401:mortality*; D008297:Male
chemical_list: D000068877:Imatinib Mesylate
keywords: CML; childhood leukaemia; early response; outcome; tyrosine kinase inhibitors