title: Prebiotic potential of neutral oligo- and polysaccharides from seed mucilage of Hyptis suaveolens.
abstract: Prebiotics are selectively fermented by the gastrointestinal microflora, resulting in benefits to human health. The seed mucilage of Hyptis suaveolens contains neutral and acidic polysaccharides in a ratio of 1:1. The neutral polysaccharides consist of galactose, glucose and mannose whereas the acidic polysaccharides contain fucose, xylose and 4-O-methylglucuronic acid -residues. The growth of probiotics in the presence of total, acidic or neutral polysaccharides and oligosaccharides was tested using turbidity measurements. The majority (11 out of 14) of the tested probiotic strains significantly grew in the neutral fraction. Growth occurred with some time delay, but may be longer lasting than with other lower molecular prebiotics. The extent of growth increased with neutral polysaccharides from H. suaveolens corresponding to the externally available galactose units (20%). In conclusion, neutral poly- and oligosaccharides from H. suaveolens have a prebiotic potential characterized by a delayed but long lasting effect.
authors.affiliation: Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria. Electronic address: monika.mueller@univie.ac.at.
authors.forename: Monika
authors.initials: M
authors.lastname: Mueller
authors.affiliation: Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
authors.forename: Andrea
authors.initials: A
authors.lastname: Čavarkapa
authors.affiliation: Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
authors.forename: Frank M
authors.initials: FM
authors.lastname: Unger
authors.affiliation: Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
authors.forename: Helmut
authors.initials: H
authors.lastname: Viernstein
authors.affiliation: Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
authors.forename: Werner
authors.initials: W
authors.lastname: Praznik
mesh_terms: D005285:Fermentation / Q000502:physiology; D005690:Galactose / Q000032:analysis / Q000378:metabolism; D006801:Humans; D031331:Hyptis / Q000737:chemistry* / Q000378:metabolism; D008358:Mannose / Q000032:analysis / Q000378:metabolism; D009844:Oligosaccharides / Q000032:analysis* / Q000378:metabolism; D011134:Polysaccharides / Q000032:analysis* / Q000378:metabolism; D056692:Prebiotics / Q000032:analysis*; D019936:Probiotics / Q000032:analysis / Q000378:metabolism; D012639:Seeds / Q000737:chemistry* / Q000378:metabolism
chemical_list: D009844:Oligosaccharides; D011134:Polysaccharides; D056692:Prebiotics; D008358:Mannose; D005690:Galactose
keywords: Hyptis suaveolens; Mucilaginous seeds; Oligosaccharides; Polysaccharides; Prebiotics