title: Laryngeal involvement with fatal outcome in progressive nodular histiocytosis: A rare case report.
abstract: Progressive nodular histiocytosis (PNH) represents a very rare type of non-Langerhans cell histiocytosis. It is characterized by progressive appearance of papules and nodules without spontaneous resolution. We report a 60-year-old patient with novel clinical features in the form of extensive noduloulcerative lesions, ichthyotic patches, and laryngeal involvement culminating in fatal outcome prior to therapeutic intervention. Although the presenting features were baffling, histopathology and immunohistochemistry clinched the diagnosis of PNH.
authors.affiliation: Department of Skin and V.D., B. J. Govt. Medical College and Sassoon General Hospital, Pune, India.
authors.forename: Aarti
authors.initials: A
authors.lastname: Salunke
authors.affiliation: Department of Skin and V.D., B. J. Govt. Medical College and Sassoon General Hospital, Pune, India.
authors.forename: Vasudha
authors.initials: V
authors.lastname: Belgaumkar
authors.affiliation: Department of Skin and V.D., B. J. Govt. Medical College and Sassoon General Hospital, Pune, India.
authors.forename: Ravindranath
authors.initials: R
authors.lastname: Chavan
authors.affiliation: Department of Skin and V.D., B. J. Govt. Medical College and Sassoon General Hospital, Pune, India.
authors.forename: Rinkesh
authors.initials: R
authors.lastname: Dobariya
keywords: Laryngeal involvement; nodules; non-Langerhans cell histiocytosis