title: Association of Endoscopic Features of Gastric Mucosa withHelicobacter pyloriInfection in Chinese Patients.
abstract: The aim of this study is to identify and consolidate reliable endoscopic features associated withH. pyloriinfection in gastric mucosa, which is one of the major causes of gastric cancer. A total of 256 Chinese patients with symptomatic stomach disturbances were enrolled. Pathological examination was conducted using a light microscope and biopsy specimens stained with hematoxylin-eosin. Endoscopic examination was performed using a high resolution video endoscope. The association between endoscopic features and pathologicalH. pyloridiagnosis was compared, and endoscopic features significantly associated withH. pyloriinfection were identified. A total of 14 endoscopic features were observed. Six of the 14 endoscopic features, including mucus on the gastric mucosa, diffuse redness, spotty redness of fundic mucosa, enlarged fold, mucosal edema, and RAC (type D and type I), were highly associated withH. pyloriinfection and were significantly sensitive and specific predictors forH. pyloridiagnosis. The type R RAC was not significantly associated withH. pyloridiagnosis. Our results indicate that conventional endoscopy features can be used to diagnoseH. pyloriin Chinese patients and can help determine the risk factor for gastric cancer.
authors.affiliation: Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
authors.forename: Tao
authors.identifier: 0000-0003-1635-5335
authors.initials: T
authors.lastname: Mao
authors.affiliation: Qingdao University, Qingdao 266071, China.
authors.forename: Yan
authors.identifier: 0000-0002-0934-4681
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Toxicology, Qingdao Municipal Center for Disease Control and Prevention, Qingdao 266033, China.
authors.forename: Fan
authors.identifier: 0000-0002-6443-2916
authors.initials: F
authors.lastname: Yin
authors.affiliation: Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
authors.forename: Qingxi
authors.initials: Q
authors.lastname: Zhao
authors.affiliation: Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
authors.forename: Lin
authors.identifier: 0000-0003-2212-7478
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
authors.forename: Xueli
authors.initials: X
authors.lastname: Ding
authors.affiliation: Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
authors.forename: Zibin
authors.identifier: 0000-0002-3211-2934
authors.initials: Z
authors.lastname: Tian