title: pRB Takes an EZ Path to a Repetitive Task.
abstract: Repetitive DNA elements are essential for genome function; in this issue of Molecular Cell, Ishak et al. (2016) describe a novel mechanism of epigenetic repression at these elements that requires pRB-dependent recruitment of EZH2.
authors.affiliation: Massachusetts General Hospital Cancer Center, Laboratory of Molecular Oncology, Harvard Medical School, Charlestown, MA 02129, USA.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Sanidas
authors.affiliation: Massachusetts General Hospital Cancer Center, Laboratory of Molecular Oncology, Harvard Medical School, Charlestown, MA 02129, USA. Electronic address: dyson@helix.mgh.harvard.edu.
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Dyson
mesh_terms: D004247:DNA; D016678:Genome; D012091:Repetitive Sequences, Nucleic Acid; D016160:Retinoblastoma Protein / Q000235:genetics*
chemical_list: D016160:Retinoblastoma Protein; D004247:DNA