title: Synthesis and characterization of nontoxic chitosan-coated Fe3O4particles for patulin adsorption in a juice-pH simulation aqueous.
abstract: Chitosan-coated Fe3O4particles were prepared as a magnetic adsorbent by reverse oil-in-water micro-emulsion system using Triton X-100 as the emulsifier. Coating chitosan onto the magnetic particles was confirmed by transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectra and magnetic measurements. Chitosan-coated Fe3O4adsorbent was shown to be effective for patulin adsorption with a maximum adsorption capacity of 6.67mg/g within 5h by adding 300μg adsorbents into 10mL 200μg/L patulin aqueous. In addition, the recovery rate of chitosan-coated Fe3O4adsorbent reached to 99.95% within 60min, showed its excellent recoverable performance. Moreover, in vitro cytotoxicity and acute toxicity evaluation were also conducted, the results suggested that the chitosan-coated Fe3O4adsorbent was non-cytotoxic, and had no toxic response or histopathological changes on mice. The results of this study demonstrated that chitosan-coated Fe3O4particles are promising adsorbents for patulin removal in fruit juice industry.
authors.affiliation: College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Luo
authors.affiliation: School of Life Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116, China.
authors.forename: Zhengkun
authors.initials: Z
authors.lastname: Zhou
authors.affiliation: College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address: yuetl305@nwsuaf.edu.cn.
authors.forename: Tianli
authors.initials: T
authors.lastname: Yue
mesh_terms: D000327:Adsorption; D045744:Cell Line, Tumor; D048271:Chitosan / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D010365:Patulin; D017550:Spectroscopy, Fourier Transform Infrared; D014867:Water
chemical_list: D005290:Ferric Compounds; D014867:Water; C000499:ferric oxide; D048271:Chitosan; D010365:Patulin
keywords: Acute toxicity; Characterization; Chitosan-coated Fe(3)O(4) particles; Cytotoxicity; Patulin adsorption