title: Dentifrice Containing Extract of Rosmarinus officinalis Linn.: An Antimicrobial Evaluation.
abstract: This study aimed to evaluate the antimicrobial activity of a dentifrice containing an alcoholic extract of rosemary on oral bacteria, compared to a commercially available herbal dentifrice. Standard strains of Streptococcus mutans (ATCC 25175), Streptococcus oralis (ATCC 9811) and Lactobacillus rhamnosus (ATCC 7469) were used, as well as different toothpastes based on rosemary (TR), on propolis (TH), triclosan (positive control) (TPC) and non-fluoridated dentifrice (negative control) (TNC). Bacteria were seeded in Petri dishes and paper discs soaked with dilutions of dentifrice placed on the plates. The inhibition halos were analyzed. It was observed that TR did not show statistical difference in relation to the TH to inhibit S. mutans and S. oralis, while TH was more active against L. rhamnosus. The toothpaste containing rosemary extract had the ability to inhibit the growth of S. mutans, S. oralis and L. rhamnosus, revealing an antimicrobial activity similar to commercially available toothpastes for inhibition of S. mutans and S. oralis.
authors.affiliation: Department of Clinical and Preventive Dentistry, UFPE - Universidade Federal de Pernambuco, Recife, PE, Brazil.
authors.forename: Marcela Agne Alves
authors.initials: MA
authors.lastname: Valones
authors.affiliation: Department of Toxicology, School of Pharmacy, UFPE - Universidade Federal de Pernambuco, Recife, PE, Brazil.
authors.forename: Jane Sheila
authors.initials: JS
authors.lastname: Higino
authors.affiliation: Department of Biology, Biology School, UFRPE - Universidade Federal Rural de Pernambuco, Recife, PE, Brazil.
authors.forename: Paulo Roberto Eleutério
authors.initials: PR
authors.lastname: Souza
authors.affiliation: LIKA - Keizo Asami Laboratory of Immunopathology, UFPE - Universidade Federal de Pernambuco, Recife, PE, Brazil.
authors.forename: Sérgio
authors.initials: S
authors.lastname: Crovella
authors.affiliation: Department of Clinical and Preventive Dentistry, UFPE - Universidade Federal de Pernambuco, Recife, PE, Brazil.
authors.forename: Arnaldo de França
authors.initials: AF
authors.lastname: Caldas
authors.affiliation: Department of Clinical and Preventive Dentistry, UFPE - Universidade Federal de Pernambuco, Recife, PE, Brazil.
authors.forename: Alessandra de Albuquerque Tavares
authors.initials: AA
authors.lastname: Carvalho
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D003802:Dentifrices; D006801:Humans; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D027542:Rosmarinus / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D003802:Dentifrices; D010936:Plant Extracts