title: Preparation of oxidized sodium alginate with different molecular weights and its application for crosslinking collagen fiber.
abstract: A series of periodate oxidized sodium alginate (OSA) were prepared as green polysaccharide-based crosslinkers. The molecular weight of OSA decreased, while their aldehyde group content increased with increasing dosage of sodium periodate. A typical OSA was further fractionated to four fractions by ethanol with a narrower molecular weight distribution. Then the crosslinking performances of OSAs/fractions on collagen fiber (CF) were investigated. DSC and SEM analyses showed that the thermal stability and dispersion degree of crosslinked CF was considerably enhanced with decreasing molecular weight of OSA. The effect of aldehyde group content of OSA on its crosslinking performance was less obvious than that of molecular weight, probably because the aldehyde group content in each OSA sample was higher than the amino group content of CF involved in the crosslinking reaction. In general, molecular weight of OSA plays a decisive role in improving properties of the crosslinked CF.
authors.affiliation: National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Ding
authors.affiliation: National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, PR China.
authors.forename: Jianfei
authors.initials: J
authors.lastname: Zhou
authors.affiliation: National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, PR China.
authors.forename: Yunhang
authors.initials: Y
authors.lastname: Zeng
authors.affiliation: National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, PR China. Electronic address: wangyanan@scu.edu.cn.
authors.forename: Ya-Nan
authors.initials: YN
authors.lastname: Wang
authors.affiliation: National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, PR China; Key Laboratory of Leather Chemistry and Engineering (Sichuan University), Ministry of Education, Chengdu 610065, PR China.
authors.forename: Bi
authors.initials: B
authors.lastname: Shi
mesh_terms: D000464:Alginates / Q000737:chemistry*; D003094:Collagen / Q000737:chemistry*; D003432:Cross-Linking Reagents; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D008970:Molecular Weight
chemical_list: D000464:Alginates; D003432:Cross-Linking Reagents; D006603:Hexuronic Acids; D020723:Glucuronic Acid; D003094:Collagen
keywords: Acetone (PubChem CID: 180); Aldehyde group; Collagen fiber; Crosslinking performance; Ethanol (PubChem CID: 702); Ethylene glycol (PubChem CID: 174); Hydroxylamine hydrochloride (PubChem CID: 443297); Molecular weight; Oxidation; Sodium alginate; Sodium alginate (PubChem CID: 5102882); Sodium periodate (PubChem CID: 23667635)