title: Early Prediction of Sepsis Incidence in Critically Ill Patients Using Specific Genetic Polymorphisms.
abstract: Several diagnostic methods for the evaluation and monitoring were used to find out the pro-inflammatory status, as well as incidence of sepsis in critically ill patients. One such recent method is based on investigating the genetic polymorphisms and determining the molecular and genetic links between them, as well as other sepsis-associated pathophysiologies. Identification of genetic polymorphisms in critical patients with sepsis can become a revolutionary method for evaluating and monitoring these patients. Similarly, the complications, as well as the high costs associated with the management of patients with sepsis, can be significantly reduced by early initiation of intensive care.
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Vlad Laurentiu
authors.initials: VL
authors.lastname: David
authors.affiliation: Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Muhammed Furkan
authors.initials: MF
authors.lastname: Ercisli
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania. alexandru.rogobete@umft.ro.|Clinic of Anesthesia and Intensive Care, Emergency County Hospital "Pius Brinzeu", Timisoara, Romania. alexandru.rogobete@umft.ro.
authors.forename: Alexandru Florin
authors.identifier: http://orcid.org/0000-0003-1286-4431
authors.initials: AF
authors.lastname: Rogobete
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Eugen S
authors.initials: ES
authors.lastname: Boia
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Razvan
authors.initials: R
authors.lastname: Horhat
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Razvan
authors.initials: R
authors.lastname: Nitu
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Mircea M
authors.initials: MM
authors.lastname: Diaconu
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Laurentiu
authors.initials: L
authors.lastname: Pirtea
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Ioana
authors.initials: I
authors.lastname: Ciuca
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Delia
authors.initials: D
authors.lastname: Horhat
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Florin George
authors.initials: FG
authors.lastname: Horhat
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Monica
authors.initials: M
authors.lastname: Licker
authors.affiliation: Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Sonia Elena
authors.initials: SE
authors.lastname: Popovici
authors.affiliation: Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Sonia
authors.initials: S
authors.lastname: Tanasescu
authors.affiliation: Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Calin
authors.initials: C
authors.lastname: Tataru
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D016638:Critical Illness; D042241:Early Diagnosis; D006801:Humans; D015994:Incidence; D011110:Polymorphism, Genetic / Q000235:genetics*; D018805:Sepsis / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics
chemical_list: D015415:Biomarkers
keywords: Biomarkers; Critically ill patients; Genetic polymorphisms; Sepsis; miRNAs