title: What prenatal ultrasound features are predictable of complex or vanishing gastroschisis? A retrospective study.
abstract: OBJECTIVE
  To evaluate prenatal ultrasound parameters as prognostic factors for complex and vanishing gastroschisis.
  
  
  METHODS
  Retrospective multicentre study of 200 gastroschisis over 13 years (2000-2013). Collection of prenatal ultrasound evaluation on maternal and fetal growth parameters, intra- and extra-abdominal bowel and stomach dilation, abdominal wall defect diameter and changes in bowel appearance. Correlation of these factors with the presence of mechanical intestinal complications at birth, named 'complex gastroschisis'.
  
  
  RESULTS
  Fifty-two patients (26%) had complex gastroschisis (CG), including ten vanishing gastroschisis. The presence of intra-abdominal bowel dilation at the second (T2) or third (T3) trimester ultrasound was predictive for CG, with odds ratios at 6.69 (95%CI 2.41-18.55) and 4.72 (95%CI 2.16-10.28), respectively, with a cut-off value at the last examination of >19 mm. A small abdominal wall defect diameter was also predictive for CG, with cut-off values of <9.2 mm at T2 and <12.5 mm at T3. Vanishing gastroschisis recorded earlier intra-abdominal bowel dilation diagnosis, associated with a small wall defect and no extra-abdominal dilation.
  
  
  CONCLUSIONS
  Intra-abdominal bowel dilation and a small abdominal wall defect diameter accurately predict CG and could be a first sign of vanishing gastroschisis when they occur early. © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Paediatric Surgery Department, University Hospital of Angers, Angers, France.|Paediatric Surgery Department, University Hospital of Lyon, Lyon, France.
authors.forename: Dorothée
authors.initials: D
authors.lastname: Geslin
authors.affiliation: Paediatric Surgery Department, University Hospital of Nantes, Nantes, France.|Paediatric Surgery Department, Robert Debré University Hospital, Paris, France.
authors.forename: Pauline
authors.initials: P
authors.lastname: Clermidi
authors.affiliation: Paediatric Surgery Department, University Hospital of Poitiers, Poitiers, France.|Paediatric Surgery Department, University Hospital of Rennes, Rennes, France.
authors.forename: Marie-Eve
authors.initials: ME
authors.lastname: Gatibelza
authors.affiliation: Department of Obstetrics and Gynecology, Angers University, Angers, France.
authors.forename: Françoise
authors.initials: F
authors.lastname: Boussion
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Brest, Brest, France.
authors.forename: Anne-Hélène
authors.initials: AH
authors.lastname: Saliou
authors.affiliation: Paediatric Surgery Department, Le Mans Hospital, Le Mans, France.
authors.forename: Gaëlle
authors.initials: G
authors.lastname: Le Manac'h Dove
authors.affiliation: Paediatric Surgery Department, Le Mans Hospital, Le Mans, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Margaryan
authors.affiliation: Paediatric Surgery Department, University Hospital of Brest, Brest, France.
authors.forename: Philine
authors.initials: P
authors.lastname: De Vries
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Bordeaux, Bordeaux, France.
authors.forename: Loïc
authors.initials: L
authors.lastname: Sentilhes
authors.affiliation: Paediatric Surgery Department, University Hospital of Poitiers, Poitiers, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Levard
authors.affiliation: Paediatric Surgery Department, University Hospital of Tours, Tours, France.
authors.forename: Hubert
authors.initials: H
authors.lastname: Lardy
authors.affiliation: Paediatric Surgery Department, University Hospital of Rennes, Rennes, France.
authors.forename: Alexis
authors.initials: A
authors.lastname: Arnaud
authors.affiliation: Paediatric Surgery Department, University Hospital of Nantes, Nantes, France.
authors.forename: Marc-David
authors.initials: MD
authors.lastname: Leclair
authors.affiliation: Paediatric Surgery Department, University Hospital of Angers, Angers, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Podevin
authors.affiliation: Paediatric Surgery Department, University Hospital of Angers, Angers, France.
authors.forename: Françoise
authors.identifier: http://orcid.org/0000-0002-3863-7694
authors.initials: F
authors.lastname: Schmitt
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging / Q000473:pathology; D000328:Adult; D004108:Dilatation, Pathologic; D005260:Female; D047109:Fetal Development; D020139:Gastroschisis / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D007422:Intestines / Q000000981:diagnostic imaging / Q000473:pathology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D011379:Prognosis; D012075:Remission, Spontaneous; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal / Q000706:statistics & numerical data; D055815:Young Adult