title: Liposome technologies and drug delivery to the CNS.
abstract: Brain and nervous system disorders represent a large unmet medical need. Central nervous system drug development is hampered by the restricted transport of drugs across the blood-brain barrier. Different strategies to deliver drugs to the brain have been developed. We discuss the current status of development of liposomal drug delivery to the brain. There is a growing interest in targeted delivery of liposomes to the brain and much progress has been made towards successful development of novel treatments for patients with devastating brain diseases.
authors.affiliation: Eyesiu Medicines BV, J.H. Oortweg 19, 2333CH Leiden, The Netherlands.
authors.forename: Jaap
authors.initials: J
authors.lastname: Rip
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D016503:Drug Delivery Systems; D006801:Humans; D008081:Liposomes
chemical_list: D008081:Liposomes