title: Relevance of prognostic factors in the decision-making of stem cell transplantation in Myelodysplastic Syndromes.
abstract: The hematopoietic stem cell transplantation (HSCT) is the only curative alternative for Myelodysplastic Syndrome (MDS), but many patients are not eligible for this treatment, as there are several limiting factors, especially in the case of patients with low-risk MDS. The aim of this study is to discuss the factors that can guide the decision-making on referring or not a patient to HSCT. Three cases of MDS, two of which were submitted to HSCT are presented. We intend to report the difficulties in referring patients with MDS to transplant and the prognostic factors that contribute to define eligibility.
authors.affiliation: Bone Marrow Transplantation Service, Hospital Universitário Walter Cantídio, Centro de Hematologia e Hemoterapia do Ceará, Brazil.
authors.forename: Fernando Barroso
authors.initials: FB
authors.lastname: Duarte
authors.affiliation: Hemoglobinopathies and Genetics, Hematological Diseases, Universidade Federal do Ceará, Brazil.
authors.forename: Talyta Ellen de Jesus Dos
authors.initials: TE
authors.lastname: Santos
authors.affiliation: Hemoglobinopathies and Genetics, Hematological Diseases, Universidade Federal do Ceará, Brazil.
authors.forename: Maritza Cavalcante
authors.initials: MC
authors.lastname: Barbosa
authors.affiliation: Bone Marrow Transplantation Service, Hospital Universitário Walter Cantídio, Brazil.
authors.forename: Jacques
authors.initials: J
authors.lastname: Kaufman
authors.affiliation: Bone Marrow Transplantation Service, Hospital Universitário Walter Cantídio, Brazil.
authors.forename: João Paulo de
authors.initials: JP
authors.lastname: Vasconcelos
authors.affiliation: Department of Clinical and Toxicological Analyses, Universidade Federal do Ceará, Brazil.
authors.forename: Romélia Pinheiro Gonçalves
authors.initials: RP
authors.lastname: Lemes
authors.affiliation: Hospital Universitário Walter Cantídio, Brazil.
authors.forename: Francisco Dário
authors.initials: FD
authors.lastname: Rocha
authors.affiliation: Molecular Biology Laboratory, Instituto Nacional do Câncer, Brazil.
authors.forename: Diego Ferreira
authors.initials: DF
authors.lastname: Coutinho
authors.affiliation: Instituto Nacional do Câncer, Brazil.
authors.forename: Ilana
authors.initials: I
authors.lastname: Zalcberg
authors.affiliation: aff11, Brazil.
authors.forename: Paulo Roberto Leitão de
authors.initials: PR
authors.lastname: Vasconcelos
mesh_terms: D000368:Aged; D003657:Decision Making; D017809:Fatal Outcome; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D018570:Risk Assessment