title: Insulated-tip knife endoscopic polypectomy for difficult pedunculated colorectal polyps: a prospective pilot study.
abstract: BACKGROUND
  Endoscopic polypectomy is widely used for colorectal polyps. However, for giant pedunculated colorectal polyps (≥3 cm), conventional techniques are so difficult with en bloc resection that patients had to be transferred to surgery. We had firstly reported our first experience with an insulated-tip knife to successfully remove a giant pedunculated polyp in the sigmoid colon. In this study, our aim was to explore safety and feasible of insulated-tip knife endoscopic polypectomy (IT-EP) for difficult pedunculated colorectal polyps.
  
  
  METHODS
  A total of seven consecutive patients with giant pedunculated colorectal polyps (≥3 cm) were prospectively enrolled. IT-EP was conducted with the help of clips for all the seven patients, and data of them was recorded and analyzed.
  
  
  RESULTS
  Of seven patients, five were men and two were women with a mean age 61 years (49-72 years). The mean diameter of polyp head and stalk was 36.4 ± 4.9 mm (30-42 mm) and 14.6 ± 3.6 mm (10-20 mm), respectively. All the polyps were successfully removed with IT-EP, with a mean operation time of 14.9 ± 3.5 min (11-20 min). No serious bleeding or perforation was experienced, and no surgery was needed. There was no recurrence or residual of polyps at a mean 8.1-month follow-up.
  
  
  CONCLUSIONS
  Insulated-tip knife endoscopic polypectomy is a safe and feasible alternative for difficult pedunculated colorectal polyps.
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.|Department of Endoscopy, China-Japan Union Hospital of Jilin University, Jilin, 130033, China.
authors.forename: Lianjun
authors.initials: L
authors.lastname: Ma
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.
authors.forename: Yaqi
authors.initials: Y
authors.lastname: Zhai
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.
authors.forename: Ningli
authors.initials: N
authors.lastname: Chai
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.
authors.forename: Huikai
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.
authors.forename: Li
authors.initials: L
authors.lastname: Yan
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.
authors.forename: Zhenjuan
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China.
authors.forename: Xiuxue
authors.initials: X
authors.lastname: Feng
authors.affiliation: Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, 100853, China. linghuenqiang@vip.sina.com.
authors.forename: Enqiang
authors.initials: E
authors.lastname: Linghu
mesh_terms: D000368:Aged; D003111:Colonic Polyps / Q000601:surgery*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies
keywords: Colorectal polyps; Endoscopic polypectomy; Insulated-tip knife