title: Surgery and Hepatocellular Carcinoma.
abstract: The optimal surgical strategy for hepatocellular carcinoma (HCC) is under active debate. Bio-markers of the liver functional reserve as well as volumetric analysis of the future liver remnant are essential for safe liver resection of HCC. The present algorithms applied to surgical strategies for HCC are not ideal because many patients who could potentially undergo safe resection are deemed liver transplant candidates in Western countries, whereas the opposite is the case in Eastern countries. In addition, there is too much focus on expanded criteria for patients with HCC to undergo liver transplantation. The transplantation benefit for patients with HCC should be considered based not only on the individual's benefit, but also on the effect of other patients waiting for LT for other indications.
authors.affiliation: Hepato-Biliary-Pancreatic Surgery Division, Artificial Organ and Organ Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Nobuhisa
authors.initials: N
authors.lastname: Akamatsu
authors.affiliation: Unità di Chirurgia Epatobiliare e Trapianto Epatico, Azienda Ospedaliera, Università di Padova, Padova, Italy.
authors.forename: Umberto
authors.initials: U
authors.lastname: Cillo
authors.affiliation: Department of Medical and Surgical Sciences, DIMEC; S. Orsola, Malpighi Hospital; Alma Mater Studiorum, University of Bologna, Bologna, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Cucchetti
authors.affiliation: Department of Surgery, Division of Hepatobiliary and General Surgery, Humanitas University and Humanitas Research Hospital, Milan, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Donadon
authors.affiliation: Department of Medical and Surgical Sciences, DIMEC; S. Orsola, Malpighi Hospital; Alma Mater Studiorum, University of Bologna, Bologna, Italy.
authors.forename: Antonio Daniele
authors.initials: AD
authors.lastname: Pinna
authors.affiliation: Department of Surgery, Division of Hepatobiliary and General Surgery, Humanitas University and Humanitas Research Hospital, Milan, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Torzilli
authors.affiliation: Hepato-Biliary-Pancreatic Surgery Division, Artificial Organ and Organ Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Norihiro
authors.initials: N
authors.lastname: Kokudo
keywords: Hepatocellular carcinoma; Liver resection; Liver transplantation