title: Syphilitic Aortitis Presenting with Coronary Ostial Stenosis and Aortic Regurgitation.
abstract: Bilateral coronary ostial stenosis without additional coronary artery involvement is a rare presentation of syphilitic aortitis, with most cases being identified post-mortem. Herein is presented a case of bilateral coronary ostial stenosis and aortic valve insufficiency caused by syphilitic aortitis without aneurysmal dilatation of the aorta. The patient underwent aortic root replacement and coronary artery bypass grafting. The intraoperative macroscopic findings raised the suspicion of an aortitis that was later confirmed to syphilitic aortitis on histological examination. It is of note that syphilis can be a cause of bilateral ostial stenosis in young adults with no predisposition to atherosclerosis, especially if combined with aortic insufficiency resulting from an isolated leaflet dysfunction.
authors.affiliation: Department Cardiology, Klinikum Braunschweig, Germany.
authors.forename: Rayyan
authors.initials: R
authors.lastname: Jadeed
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Klinikum Braunschweig, Germany.
authors.forename: Ruth
authors.initials: R
authors.lastname: Paarmann
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Klinikum Braunschweig, Germany.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Harringer
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Klinikum Braunschweig, Germany.
authors.forename: Aschraf
authors.initials: A
authors.lastname: El-Essawi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects / Q000379:methods; D017023:Coronary Angiography / Q000379:methods; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy; D004401:Dysarthria / Q000209:etiology; D017548:Echocardiography, Transesophageal / Q000379:methods; D004917:Erythromycin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010291:Paresis / Q000209:etiology; D012307:Risk Factors; D013589:Syphilis, Cardiovascular / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D016896:Treatment Outcome; D014965:X-Rays
chemical_list: D000900:Anti-Bacterial Agents; D004917:Erythromycin