title: Case profile, volume analysis, and dropout rate of antirabies vaccination regimens among animal bite victims in Gujarat.
abstract: BACKGROUND
  Rabies is a preventable neglected public health problem and associated with multiple cultural, religious, and social practices, myths in our country. There is a lack of organized surveillance system to measure the incidence of animal bite and human rabies as well as to evaluate cost-saving of different routes, regimen, and types of antirabies vaccines (ARV)/immunoglobulin available in India.
  
  
  OBJECTIVE
  The objective of this study is to know dropout rate in intradermal (i.d.) ARV regimen among animal bite and to analyze the utilized volume of ARV by a different route of vaccine administration.
  
  
  METHODS
  A total of 250 animal bite victims were followed up at ARV Clinic (ARVC). Volume utilization of i.d. route over intramuscular (i.m.) route was analyzed among the patients who attended ARVC during the past 2 years. Total dropout and delayed compliance rates of ARV regimen among different group were compared by Chi-square test.
  
  
  RESULTS
  The i.d. route was about five times more volume and cost-saving than i.m. route. The majority of victims belonged to 15-30 years (27.60%) and children <15 years (26.40%) and had wound at their lower limbs (85%) mainly bitten by dogs (98%). Thirty-four percent total dropout and 31.5% delayed compliance observed particularly during the last dose of i.d. regimen. There was no significant difference in dropout rates among different demographic groups. Half of the victims practiced wound toilet on the same day of bite. Only 68% received the first dose of ARV within 24 h of the exposure.
  
  
  CONCLUSIONS
  Children and young adults are at higher risk of having dog bite. I.d. ARV regimen is more volume and cost-saving than i.m. one and proper counseling and follow-up should be arranged to complete the vaccination schedule.
authors.affiliation: Assistant Professor, Department of Community Medicine, Shri M. P. Shah Govt. Medical College, Jamnagar, Gujarat, India.
authors.forename: Kishor M
authors.initials: KM
authors.lastname: Dhaduk
authors.affiliation: Associate Professor, Department of Community Medicine, Shri M. P. Shah Govt. Medical College, Jamnagar, Gujarat, India.
authors.forename: Sumit V
authors.initials: SV
authors.lastname: Unadkat
authors.affiliation: Internee, Department of Community Medicine, Shri M. P. Shah Govt. Medical College, Jamnagar, Gujarat, India.
authors.forename: Pooja R
authors.initials: PR
authors.lastname: Katharotiya
authors.affiliation: Internee, Department of Community Medicine, Shri M. P. Shah Govt. Medical College, Jamnagar, Gujarat, India.
authors.forename: Ankit R
authors.initials: AR
authors.lastname: Mer
authors.affiliation: Internee, Department of Community Medicine, Shri M. P. Shah Govt. Medical College, Jamnagar, Gujarat, India.
authors.forename: Monika C
authors.initials: MC
authors.lastname: Chaudhary
authors.affiliation: Internee, Department of Community Medicine, Shri M. P. Shah Govt. Medical College, Jamnagar, Gujarat, India.
authors.forename: Mrudul M
authors.initials: MM
authors.lastname: Prajapati
mesh_terms: D000818:Animals; D001733:Bites and Stings; D002648:Child; D004285:Dogs; D006801:Humans; D007194:India; D010349:Patient Compliance; D010352:Patient Dropouts; D011818:Rabies / Q000517:prevention & control; D011819:Rabies Vaccines / Q000627:therapeutic use; D014611:Vaccination
chemical_list: D011819:Rabies Vaccines