title: Consensus guidelines for diagnosis, treatment and follow-up of patients with pancreatic cancer in Spain.
abstract: The management of patients with pancreatic cancer has advanced over the last few years. We convey a multidisciplinary group of experts in an attempt to stablish practical guidelines for the diagnoses, staging and management of these patients. This paper summarizes the main conclusions of the working group. Patients with suspected pancreatic ductal adenocarcinoma should be rapidly evaluated and referred to high-volume centers. Multidisciplinary supervision is critical for proper diagnoses, staging and to frame a treatment plan. Surgical resection together with chemotherapy offers the highest chance for cure in early stage disease. Patients with advanced disease should be classified in treatment groups to guide systemic treatment. New chemotherapeutic regimens have resulted in improved survival. Symptomatic management is critical in this disease. Enrollment in a clinical trial is, in general, recommended.
authors.affiliation: Spanish National Cancer Centre, C/Melchor Fernández Almagro, 3, 28029, Madrid, Spain. mhidalgo@cnio.es.|Beth Israel Deaconess Medical Center, Boston, USA. mhidalgo@cnio.es.
authors.forename: M
authors.initials: M
authors.lastname: Hidalgo
authors.affiliation: Department of Medical Oncology, Centro Integral Oncológico Clara Campal, Madrid, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Álvarez
authors.affiliation: University Hospital of Elche, Elche, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Gallego
authors.affiliation: Hospital Universitario Ramón y Cajal, Ctra. de Colmenar Viejo km. 9,100, 28034, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Guillén-Ponce
authors.affiliation: Institut Català d´Oncologia, Duran y Reynals Hospital, Hospitalet Llobregat, Barcelona, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Laquente
authors.affiliation: Vall d'Hebrón University Hospital, Barcelona, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Macarulla
authors.affiliation: University Hospital Gregorio Marañón, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Muñoz
authors.affiliation: University Hospital of Ourense, Ourense, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Salgado
authors.affiliation: Complejo Hospitalario de Navarra, Pamplona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Vera
authors.affiliation: University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Adeva
authors.affiliation: Hospital Carlos Haya, Málaga, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Alés
authors.affiliation: University Hospital Donostia, San Sebastián, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Arévalo
authors.affiliation: Department of Radiology, University Hospital Ramón y Cajal, Madrid, Spain.|MD Anderson Hospital, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Blázquez
authors.affiliation: Department of Palliative Care, Hospital Germans Trias I Pujol, Institut Catalá d´Oncologia, Badalona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Calsina
authors.affiliation: Department of Medical Oncology and Hematology, University Hospital Morales Messeguer, Murcia, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Carmona
authors.affiliation: Department of Gastroenterology, Hospital General Universitario de Alicante, Alicante, Spain.
authors.forename: E
authors.initials: E
authors.lastname: de Madaria
authors.affiliation: Department of Medical Oncology, Hospital Universitari I Politècnic La Fe, Valencia, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Díaz
authors.affiliation: Department of Surgery, Hospital Clínico San Carlos, Madrid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Díez
authors.affiliation: Department of Medical Oncology, Hospital Son Llàtzer, Palma de Mallorca, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Fernández
authors.affiliation: Hospital Clínico San Carlos, Madrid, Spain.
authors.forename: B G
authors.initials: BG
authors.lastname: de Paredes
authors.affiliation: Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain.
authors.forename: M E
authors.initials: ME
authors.lastname: Gallardo
authors.affiliation: Complejo Hospitalario de Granada, Granada, Spain.
authors.forename: I
authors.initials: I
authors.lastname: González
authors.affiliation: Department of Radiotherapy, University Hospital HM Sanchinarro, Madrid, Spain.|University Hospital HM Puerta del Sur, Madrid, Spain.
authors.forename: O
authors.initials: O
authors.lastname: Hernando
authors.affiliation: Department of Medical Oncology, Hospital Universitario Central de Asturias, Asturias, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Jiménez
authors.affiliation: Hospital Universitario de Burgos, Burgos, Spain.
authors.forename: A
authors.initials: A
authors.lastname: López
authors.affiliation: Hospital Universitario Marqués de Valdecilla, Santander, Spain.
authors.forename: C
authors.initials: C
authors.lastname: López
authors.affiliation: Department of Pathology, University Hospital HM Sanchinarro, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: López-Ríos
authors.affiliation: Department of Surgery, Hospital Universitario de la Princesa, Madrid, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Martín
authors.affiliation: Department of Medical Oncology, University Hospital Virgen de las Nieves, Granada, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Martínez
authors.affiliation: Hospital del Mar, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Martínez
authors.affiliation: Department of Pathology, Centro Anatomopatológico, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Montans
authors.affiliation: Department of Medical Oncology, University Hospital Miguel Servet, Saragossa, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Pazo
authors.affiliation: Department of Pathology, University Hospital HM Sanchinarro, Madrid, Spain.
authors.forename: J C
authors.initials: JC
authors.lastname: Plaza
authors.affiliation: Department of Endocrinology, Instituto Catalán de Oncología, Hospital Duran I Reynals, Hospitalet de Llobregat, Barcelona, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Peiró
authors.affiliation: Department of Medical Oncology, University Hospital Virgen de la Macarena, Seville, Spain.
authors.forename: J J
authors.initials: JJ
authors.lastname: Reina
authors.affiliation: Department of Surgery, University Hospital Ramón y Cajal, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Sanjuanbenito
authors.affiliation: Department of Medical Oncology, Fundación Instituto Valenciano de Oncología, Valencia, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Yaya
authors.affiliation: Hospital Universitario Ramón y Cajal, Ctra. de Colmenar Viejo km. 9,100, 28034, Madrid, Spain. acarrato@telefonica.net.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Carrato
mesh_terms: D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis* / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D017410:Practice Guidelines as Topic; D013030:Spain
keywords: Consensus guidelines; Diagnosis; Pancreatic cancer; Treatment