title: Short-Term Efficacy of Pudilan Keyanning Toothpaste in Treatment of Minor Recurrent Aphthous Ulcers.
abstract: Aim. To examine the potential of Pudilan Keyanning toothpaste (PKT) to treat minor aphthous ulcers (MiAU).Method. A double-blind clinical trial was conducted in which 80 volunteers were randomly assigned to the PKT group (N= 40) or the control group (N= 40). The control group used a placebo toothpaste containing no Pudilan extract. At baseline, after 3 days, and after 6 days the following parameters were recorded for the target ulcers: healing rate, healing period, pain (visual analogue scale, VAS), areas of the target ulcerated lesions, degree of exudation, and hyperemia.Results. At the end of the study, the healing rate in the PKT group was 80%, compared to 50% in the control group (p< 0.05). At day 6, the VAS scores, ulcer area, degree of exudation, and hyperemia were significantly different between the two groups, with better performance observed in the PKT group (p< 0.05).Conclusion. PKT toothpaste appears to promote effective healing of MiAU.
authors.affiliation: Department of Preventive Dentistry, West China School and Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Yingming
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Preventive Dentistry, West China School and Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Nanjing University of Chinese Medicine, Nanjing 210023, China.
authors.forename: Zibo
authors.initials: Z
authors.lastname: Dong
authors.affiliation: Department of Preventive Dentistry, West China School and Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Preventive Dentistry, West China School and Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Xiao
authors.identifier: 0000-0001-7678-9560
authors.initials: X
authors.lastname: Hong
authors.affiliation: Department of Preventive Dentistry, West China School and Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
authors.forename: Tao
authors.identifier: 0000-0002-0418-1246
authors.initials: T
authors.lastname: Hu