title: Pectinate ligament dysplasia in the Border Collie, Hungarian Vizsla and Golden Retriever.
abstract: Pectinate ligament dysplasia (PLD) is significantly associated with primary closed angle glaucoma (PCAG) in several dog breeds. Gonioscopy screening for PLD is advised in breeds in which PLD and PCAG are particularly prevalent in order that affected dogs may be eliminated from the breeding population. The Border Collie (BC), Hungarian Vizsla (HV) and Golden Retriever (GR) breeds are currently under investigation for PLD by the British Veterinary Association/Kennel Club/International Sheep Dog Society (BVA/KC/ISDS) Eye Scheme. The authors aimed to determine the prevalence of PLD in UK populations of BC, HV and GR and to investigate possible associations between the degree of PLD and age and sex. Gonioscopy was performed in 102 BCs, 112 HVs and 230 GRs and the percentage of iridocorneal angle affected by PLD was estimated and classified as unaffected (0 per cent), mildly affected (<20 per cent), moderately affected (20-90 per cent) or severely affected (>90 per cent). Eleven of 102 (13.8 per cent) BCs, 16/112 (14.3 per cent) HVs and 60/230 (26.1 per cent) GRs were moderately or severely affected by PLD. The prevalence of PLD was significantly higher in GR than both BC and HV. There was a significant positive correlation between PLD and age in the HV and GR but not in the BC. There was no association between PLD and sex in any breed.
authors.affiliation: Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK.
authors.forename: James A C
authors.initials: JA
authors.lastname: Oliver
authors.affiliation: One Health Institute, School of Veterinary Medicine, University of California, Davis, California, USA.
authors.forename: Abel B
authors.initials: AB
authors.lastname: Ekiri
authors.affiliation: Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK.
authors.forename: Cathryn S
authors.initials: CS
authors.lastname: Mellersh
mesh_terms: D000818:Animals; D001947:Breeding; D004283:Dog Diseases / Q000453:epidemiology*; D004285:Dogs; D005128:Eye Diseases / Q000453:epidemiology / Q000662:veterinary*; D005260:Female; D006068:Gonioscopy / Q000662:veterinary; D008297:Male; D015995:Prevalence; D006113:United Kingdom / Q000453:epidemiology
keywords: Border Collie; Glaucoma; Golden Retriever; Goniodysgenesis; Hungarian Vizsla; Pectinate ligament dysplasia