title: A concise drug alerting rule set for Chinese hospitals and its application in computerized physician order entry (CPOE).
abstract: BACKGROUND
  A minimized and concise drug alerting rule set can be effective in reducing alert fatigue.
  
  
  OBJECTIVE
  This study aims to develop and evaluate a concise drug alerting rule set for Chinese hospitals. The rule set covers not only western medicine, but also Chinese patent medicine that is widely used in Chinese hospitals.
  
  
  METHODS
  A 2600-bed general hospital in China.
  
  
  METHODS
  In order to implement the drug rule set in clinical information settings, an information model for drug rules was designed and a rule authoring tool was developed accordingly. With this authoring tool, clinical pharmacists built a computerized rule set that contains 150 most widely used and error-prone drugs. Based on this rule set, a medication-related clinical decision support application was built in CPOE. Drug alert data between 2013/12/25 and 2015/07/01 were used to evaluate the effect of the rule set.
  
  
  METHODS
  Number of alerts, number of corrected/overridden alerts, accept/override rate.
  
  
  RESULTS
  Totally 18,666 alerts were fired and 2803 alerts were overridden. Overall override rate is 15.0% (2803/18666) and accept rate is 85.0%.
  
  
  CONCLUSIONS
  The rule set has been well received by physicians and can be used as a preliminary medical order screening tool to reduce pharmacists' workload. For Chinese hospitals, this rule set can serve as a starter kit for building their own pharmaceutical systems or as a reference to tier commercial rule set.
authors.affiliation: School of Computer Science and Information Engineering, Zhejiang Gongshang University, Hangzhou, 310018 Zhejiang People's Republic of China.
authors.forename: Yinsheng
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, 310027 Zhejiang People's Republic of China.
authors.forename: Xin
authors.initials: X
authors.lastname: Long
authors.affiliation: Department of Pharmacy, DaYi Hospital, Taiyuan, 030012 ShanXi People's Republic of China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Chen
authors.affiliation: Children's Hospital, Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, 310058 Zhejiang People's Republic of China.
authors.forename: Haomin
authors.initials: H
authors.lastname: Li
authors.affiliation: College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, 310027 Zhejiang People's Republic of China.
authors.forename: Huilong
authors.initials: H
authors.lastname: Duan
authors.affiliation: Management School, Hangzhou Dianzi University, Hangzhou, 310058 Zhejiang People's Republic of China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Shang
keywords: Alert fatigue; Chinese patent medicine; Drug alerting rule; Medication-related clinical decision support