title: 5 -year complex clinical and histopathological follow-up of a case of early gastric carcinoma (signet ring cells type).
abstract: The paper presents the case of a male patient, hospitalized for acute abdomen due to perforated callous ulcer. Though the clinical appearance suggested a benign pathology, the histopathological exam of the resection piece showed multicentric early gastric carcinoma, signet ring cell type. At the patient's request, total gastrectomy was not performed, a conservative solution being chosen instead. Superior digestive endoscopy with biopsy and oncological dispensarization was performed one month after surgery, then at every 6 months. After 2 years of benign results, the histopathological exam revealed the presence of malign singlet ring cells in the bioptic specimen. Respecting the patient's option of preserving a good quality of life, subtotal gastrectomy with Pean type gastroenteroanastomosis was performed followed by postoperatory chemotherapy. Endoscopic and oncological follow-up were performed at every six months for another 3 years (up to present), and the evolution was favorable with no local or metastatic recurrence. Histopathological examination was of great help in the surgical management of this case, allowing a fortunate early diagnosis, a conservative surgical approach, and the preserving of a good quality of life.
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: D
authors.initials: D
authors.lastname: Serban
authors.affiliation: IVth Upper Digestive Surgery Clinic, University Emergency Hospital, Bucharest, Romania.
authors.forename: C
authors.initials: C
authors.lastname: Branescu
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: C
authors.initials: C
authors.lastname: Savlovschi
authors.affiliation: IVth Upper Digestive Surgery Clinic, University Emergency Hospital, Bucharest, Romania.
authors.forename: G
authors.initials: G
authors.lastname: Simion
authors.affiliation: IVth Upper Digestive Surgery Clinic, University Emergency Hospital, Bucharest, Romania.
authors.forename: A
authors.initials: A
authors.lastname: Mihai
authors.affiliation: IVth Upper Digestive Surgery Clinic, University Emergency Hospital, Bucharest, Romania.
authors.forename: A
authors.initials: A
authors.lastname: El-Khatib
authors.affiliation: IVth Upper Digestive Surgery Clinic, University Emergency Hospital, Bucharest, Romania.
authors.forename: C
authors.initials: C
authors.lastname: Tudor
authors.affiliation: IVth Upper Digestive Surgery Clinic, University Emergency Hospital, Bucharest, Romania.
authors.forename: A
authors.initials: A
authors.lastname: Nica
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: G
authors.initials: G
authors.lastname: Vancea
authors.affiliation: University of Medicine and Pharmacy, Craiova, Romania.
authors.forename: M
authors.initials: M
authors.lastname: Ghelase
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; IVth Upper Digestive Surgery Clinic, University Emergency Hospital, Bucharest, Romania.
authors.forename: A M
authors.initials: AM
authors.lastname: Dascalu
mesh_terms: D042241:Early Diagnosis; D005500:Follow-Up Studies; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000473:pathology* / Q000523:psychology / Q000601:surgery
keywords: early gastric carcinoma; histopathology; multifocal; signet ring cell; surgery