title: In Vivo Validation of Volume Flow Measurements of Pulsatile Flow Using a Clinical Ultrasound System and Matrix Array Transducer.
abstract: The goal of this study was to evaluate the accuracy of a non-invasive C-plane Doppler estimation of pulsatile blood flow in the lower abdominal vessels of a porcine model. Doppler ultrasound measurements from a matrix array transducer system were compared with invasive volume flow measurements made on the same vessels with a surgically implanted ultrasonic transit-time flow probe. For volume flow rates ranging from 60 to 750 mL/min, agreement was very good, with a Pearson correlation coefficient of 0.97 (p < 0.0001) and a mean bias of -4.2%. The combination of 2-D matrix array technology and fast processing gives this Doppler method clinical potential, as many of the user- and system-dependent parameters of previous methods, including explicit vessel angle and diameter measurements, are eliminated.
authors.affiliation: Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
authors.forename: John M
authors.initials: JM
authors.lastname: Hudson
authors.affiliation: Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
authors.forename: Ross
authors.initials: R
authors.lastname: Williams
authors.affiliation: Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
authors.forename: Laurent
authors.initials: L
authors.lastname: Milot
authors.affiliation: Philips Ultrasound, Bothell, Washington, USA.
authors.forename: Qifeng
authors.initials: Q
authors.lastname: Wei
authors.affiliation: Philips Ultrasound, Bothell, Washington, USA.
authors.forename: James
authors.initials: J
authors.lastname: Jago
authors.affiliation: Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada. Electronic address: Burns@sri.utoronto.ca.
authors.forename: Peter N
authors.initials: PN
authors.lastname: Burns
mesh_terms: D000005:Abdomen / Q000098:blood supply* / Q000000981:diagnostic imaging; D000818:Animals; D005260:Female; D023421:Models, Animal; D011673:Pulsatile Flow / Q000502:physiology*; D012039:Regional Blood Flow / Q000502:physiology*; D015203:Reproducibility of Results; D013552:Swine; D014159:Transducers; D018608:Ultrasonography, Doppler / Q000379:methods*
keywords: Volume flow