title: One new lignan derivative from the Combretum alfredii Hance.
abstract: One new lignan derivative 2,3-dimethyl-4-(4-methoxyphenyl)-6,7-dihydroxynaphthalene (1), together with five known compounds (2-6), were isolated from ethanol extract of the branches and leaves of Combretum alfredii Hance collected in Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compounds 1, 2, 5 and 6 were isolated from the genus of Combretum for the first time. All compounds were evaluated for their antibacterial activities. Compounds 1 and 2 showed significant antibacterial activities against six pathogenic bacteria.
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Meng
authors.initials: M
authors.lastname: Bai
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Wu
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Cai
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Shou-Yuan
authors.initials: SY
authors.lastname: Wu
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Song
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Guang-Ying
authors.initials: GY
authors.lastname: Chen
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Cai-Juan
authors.initials: CJ
authors.lastname: Zheng
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.|b Hainan Institute of Science and Technology , Haikou , People's Republic of China.
authors.forename: Chang-Ri
authors.initials: CR
authors.lastname: Han
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D029765:Combretum / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009284:Naphthols; D010936:Plant Extracts / Q000032:analysis; D018515:Plant Leaves / Q000737:chemistry
chemical_list: C000619992:2,3-dimethyl-4-(4-methoxyphenyl)-6,7-dihydroxynaphthalene; D000900:Anti-Bacterial Agents; D017705:Lignans; D009284:Naphthols; D010936:Plant Extracts
keywords: Combretum alfredii Hance; antibacterial activity; chemical constituents