title: Prospective registry for laparoscopic liver resection.
abstract: BACKGROUND
  Laparoscopic liver resection (LLR) has been widely performed throughout the world. Although prospective registry studies to clarify the safety of LLR have been feasible, no prior multicenter prospective study has addressed this issue. We have conducted a multicenter prospective cohort study to reveal the current status of LLR in Japan.
  
  
  METHODS
  From April 2015 to March 2016, candidates for LLR were preoperatively enrolled at 12 institutions. The primary end-point was surgical safety, which was evaluated based on surgical factors and on short-term and midterm outcomes.
  
  
  RESULTS
  A total of 102 patients were enrolled. Planned laparoscopic procedures included 96 pure laparoscopies, 1 hand-assisted laparoscopy, and 5 hybrid techniques. Non-anatomical partial resection or left lateral sectionectomy were performed in almost all cases. The median duration of surgery was 221 min. The median blood loss was 80.5 mL. Conversion was required for four patients (3.9%). The 90-day postoperative morbidities with grades more severe than II in the Clavien-Dindo classification were observed in six patients (5.9%). The median postoperative hospital stay was 9.5 days. No cases involved reoperation or mortality.
  
  
  CONCLUSIONS
  Minor resection of LLR has been performed safely. To ensure the safe dissemination of LLR, including for major resection, a larger multicenter prospective study is required.
authors.affiliation: Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Fuji
authors.affiliation: Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.|Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan.
authors.forename: Etsuro
authors.initials: E
authors.lastname: Hatano
authors.affiliation: Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Seo
authors.affiliation: Department of Surgery, Osaka Red Cross Hospital, Osaka, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Arimoto
authors.affiliation: Department of Surgery, Kurashiki Central Hospital, Kurashiki, Japan.
authors.forename: Michio
authors.initials: M
authors.lastname: Okabe
authors.affiliation: Department of Surgery, Kokura Memorial Hospital, Kitakyu-shu, Japan.
authors.forename: Takahisa
authors.initials: T
authors.lastname: Fujikawa
authors.affiliation: Department of Surgery, Kyoto Katsura Hospital, Kyoto, Japan.
authors.forename: Ryuta
authors.initials: R
authors.lastname: Nishitai
authors.affiliation: Department of Surgery, Nishi Kobe Medical Center, Kobe, Japan.
authors.forename: Takamichi
authors.initials: T
authors.lastname: Ishii
authors.affiliation: Department of Surgery, Kobe City Medical Center General Hospital, Kobe, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kaihara
authors.affiliation: Department of Surgery, National Hospital Organization Himeji Medical Center, Himeji, Japan.
authors.forename: Takakazu
authors.initials: T
authors.lastname: Matsushita
authors.affiliation: Department of Surgery, Mitsubishi Kyoto Hospital, Kyoto, Japan.
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Oike
authors.affiliation: Department of Surgery, Japan Red Cross Wakayama Medical Center, Wakayama, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Ichimiya
authors.affiliation: Department of Surgery, Osakafu Saiseikai Noe Hospital, Osaka, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Ohta
authors.affiliation: Department of Surgery, Kishiwada City Hospital, Kishiwada, Japan.
authors.forename: Kenya
authors.initials: K
authors.lastname: Yamanaka
authors.affiliation: Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Kojiro
authors.initials: K
authors.lastname: Taura
authors.affiliation: Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yasuchika
authors.affiliation: Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Uemoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007564:Japan; D010535:Laparoscopy; D008107:Liver Diseases / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D011446:Prospective Studies; D012042:Registries; D016896:Treatment Outcome
keywords: Laparoscopic surgery; liver; prospective studies