title: A case for poroelasticity in skeletal muscle finite element analysis: experiment and modeling.
abstract: Finite element models of skeletal muscle typically ignore the biphasic nature of the tissue, associating any time dependence with a viscoelastic formulation. In this study, direct experimental measurement of permeability was conducted as a function of specimen orientation and strain. A finite element model was developed to identify how various permeability formulations affect compressive response of the tissue. Experimental and modeling results suggest the assumption of a constant, isotropic permeability is appropriate. A viscoelastic only model differed considerably from a visco-poroelastic model, suggesting the latter is more appropriate for compressive studies.
authors.affiliation: a Soft Tissue Mechanics Laboratory, Department of Mechanical Engineering , Colorado State University , Fort Collins , CO , USA.
authors.forename: Benjamin B
authors.initials: BB
authors.lastname: Wheatley
authors.affiliation: b Department of Mechanical Engineering - Engineering Mechanics , Michigan Technological University , Houghton , MI , USA.
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Odegard
authors.affiliation: c Motion Analysis Laboratory, Department of Orthopedic Surgery , Mayo Clinic , Rochester , MN , USA.
authors.forename: Kenton R
authors.initials: KR
authors.lastname: Kaufman
authors.affiliation: d Soft Tissue Mechanics Laboratory, Department of Mechanical Engineering , School of Biomedical Engineering, Colorado State University , Fort Collins , CO , USA.
authors.forename: Tammy L
authors.initials: TL
authors.lastname: Haut Donahue
mesh_terms: D000818:Animals; D019245:Compressive Strength; D004548:Elasticity; D020342:Finite Element Analysis; D006801:Humans; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000502:physiology*; D010539:Permeability; D016062:Porosity; D011817:Rabbits; D013314:Stress, Mechanical
keywords: Biphasic; permeability; transversely isotropic; viscoelasticity