title: Health-Related Quality of Life of Patients with HIV/AIDS in Bogotá, Colombia.
abstract: BACKGROUND
  There has rarely been any reporting on health-related quality of life (HRQOL) of patients with HIV/AIDS in developing countries.
  
  
  OBJECTIVE
  To estimate the health utilities of people with HIV/AIDS in Bogotá, Columbia.
  
  
  METHODS
  A cross-sectional survey was conducted for 181 patients receiving antiretroviral therapy from an outpatient HIV/AIDS clinic in Bogotá. The five-level version of the EuroQol five-dimensional questionnaire (EQ-5D-5L) and the EuroQol visual analogue scale (EQ-VAS) were used to estimate HRQOL scores. To derive utilities on the basis of the EQ-5D-5L, the Spanish value set was used. Subgroup analyses were performed according to sex, age, the Centers for Disease Control and Prevention classification, and CD4 cell count.
  
  
  RESULTS
  The mean utility of the EQ-5D-5L was estimated at 0.85 ± 0.21 and the EQ-VAS score was estimated at 84 ± 14. Pain/discomfort and anxiety/depression were the two EQ-5D-5L dimensions associated with the poorer outcomes. Subgroup analyses revealed significantly higher utilities (using the EQ-5D-5L) for men than for women (0.88 vs. 0.76; P = 0.002) and lower utilities for patients with severe HIV (0.83 for CD4 < 200 vs. 0.87 for CD4 ≥ 500; P = 0.024).
  
  
  CONCLUSIONS
  The HRQOL scores of patients with HIV/AIDS receiving antiretroviral therapy were relatively high in Bogotá, Colombia, using the EuroQol questionnaire. The utility data could be useful, in combination with cost data, for future economic evaluations.
authors.affiliation: Department of Health Services Research, CAPHRI School for Primary Care and Public Health, Maastricht University, Maastricht, The Netherlands.
authors.forename: Mussa
authors.initials: M
authors.lastname: Keaei
authors.affiliation: Department of Health Services Research, CAPHRI School for Primary Care and Public Health, Maastricht University, Maastricht, The Netherlands.
authors.forename: Julien
authors.initials: J
authors.lastname: Kuhlmann
authors.affiliation: Asistencia Cientifica de Alta Compleijdad, Bogotá, Colombia; Rosario University, Bogotá, Colombia.
authors.forename: Rafael
authors.initials: R
authors.lastname: Conde
authors.affiliation: Department of Health Services Research, CAPHRI School for Primary Care and Public Health, Maastricht University, Maastricht, The Netherlands; Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands.
authors.forename: Silvia M A A
authors.initials: SM
authors.lastname: Evers
authors.affiliation: Rosario University, Bogotá, Colombia.
authors.forename: Javier
authors.initials: J
authors.lastname: Gonzalez
authors.affiliation: Department of Health Services Research, CAPHRI School for Primary Care and Public Health, Maastricht University, Maastricht, The Netherlands.
authors.forename: Mark
authors.initials: M
authors.lastname: Govers
authors.affiliation: Department of Health Services Research, CAPHRI School for Primary Care and Public Health, Maastricht University, Maastricht, The Netherlands. Electronic address: m.hiligsmann@maastrichtuniversity.nl.
authors.forename: Mickael
authors.initials: M
authors.lastname: Hiligsmann
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000628:therapy; D003105:Colombia; D003430:Cross-Sectional Studies; D003906:Developing Countries; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000628:therapy; D006304:Health Status; D006801:Humans; D008297:Male; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014481:United States
keywords: AIDS; Colombia; EQ-5D-5L; HIV; burden; quality of life; utility