title: Dendritic Mesoporous Silica Nanospheres Synthesized by a Novel Dual-Templating Micelle System for the Preparation of Functional Nanomaterials.
abstract: Highly monodisperse, dendritic, and functionalized mesoporous silica nanospheres (MSNs) with sub-200 nm size were synthesized in a one-pot sol-gel reaction, by a dual-templating micelle system consisting of a partially fluorinated short-chain anionic fluorocarbon surfactant and cetyltrimethylammonium bromide. This kind of anionic fluorocarbon surfactant works simultaneously as a swelling agent to enlarge the pore of the MSNs, an ion-pair agent to the structure-directing silane in the preparation of amine-functionalized MSNs, and a surface tension reducing agent to make the system thermodynamically more stable for producing more uniform MSNs. The particle size and the morphology of the resultant MSNs can be fine-tuned by changing the amount of the fluorocarbon surfactant added and the ratio of the functional group containing organosilane to tetraethoxysilane. Subsequently, the as-prepared MSNs were used as base materials for the preparation of drug delivery nanomaterials through the surface grafting of a pH-sensitive drug-conjugated polymer and fluorescent nanomaterials through the embedding of europium(III) complex or the immobilization of large molecule fluorescein isothiocyanate-bovine serum albumin.
authors.affiliation: College of Science, University of Shanghai for Science and Technology , Shanghai 200093, P.R. China.
authors.forename: Mingxian
authors.identifier: 0000-0002-1151-2381
authors.initials: M
authors.lastname: Huang
authors.affiliation: College of Science, University of Shanghai for Science and Technology , Shanghai 200093, P.R. China.
authors.forename: Lu
authors.initials: L
authors.lastname: Liu
authors.affiliation: College of Science, University of Shanghai for Science and Technology , Shanghai 200093, P.R. China.
authors.forename: Shige
authors.initials: S
authors.lastname: Wang
authors.affiliation: College of Science, University of Shanghai for Science and Technology , Shanghai 200093, P.R. China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Zhu
authors.affiliation: College of Science, University of Shanghai for Science and Technology , Shanghai 200093, P.R. China.
authors.forename: Dahui
authors.initials: D
authors.lastname: Wu
authors.affiliation: College of Science, University of Shanghai for Science and Technology , Shanghai 200093, P.R. China.
authors.forename: Zhihao
authors.initials: Z
authors.lastname: Yu
authors.affiliation: College of Science, University of Shanghai for Science and Technology , Shanghai 200093, P.R. China.
authors.forename: Shilin
authors.initials: S
authors.lastname: Zhou
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods; D008823:Micelles; D054118:Nanospheres / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D012821:Silanes / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D008823:Micelles; D012821:Silanes; C040733:tetraethoxysilane; D012822:Silicon Dioxide