title: Study of interactions between hyaluronan and cationic surfactants by means of calorimetry, turbidimetry, potentiometry and conductometry.
abstract: The thermodynamics of the micelle formation of the cationic surfactants tetradecyltrimethylammonium bromide (TTAB) and cetyltrimethylammonium bromide (CTAB) with and without the addition of hyaluronan of two molecular weights was studied in aqueous solution by titration calorimetry. Macroscopic phase separation, which was detected by calorimetry and also by conductometry, occurs when charges on the surfactant and hyaluronan are balanced. In contrast, turbidimetry and potentiometry showed hyaluronan-surfactant interactions at very low surfactant concentrations. The observed differences between systems prepared with CTAB and TTAB indicate that besides the electrostatic interactions, which probably predominate, hydrophobic effects also play a significant role in hyaluronan interactions with cationic surfactants.
authors.affiliation: Brno University of Technology, Faculty of Chemistry, Materials Research Centre, Purkyňova 118, 612 00 Brno, Czechia.
authors.forename: J
authors.initials: J
authors.lastname: Krouská
authors.affiliation: Brno University of Technology, Faculty of Chemistry, Materials Research Centre, Purkyňova 118, 612 00 Brno, Czechia. Electronic address: pekar@fch.vut.cz.
authors.forename: M
authors.initials: M
authors.lastname: Pekař
authors.affiliation: Brno University of Technology, Faculty of Chemistry, Materials Research Centre, Purkyňova 118, 612 00 Brno, Czechia.
authors.forename: M
authors.initials: M
authors.lastname: Klučáková
authors.affiliation: University of Ljubljana, Faculty of Chemistry and Chemical Technology, Večna pot 113, 1000 Ljubljana, Slovenia.
authors.forename: B
authors.initials: B
authors.lastname: Šarac
authors.affiliation: University of Ljubljana, Faculty of Chemistry and Chemical Technology, Večna pot 113, 1000 Ljubljana, Slovenia.
authors.forename: M
authors.initials: M
authors.lastname: Bešter-Rogač
keywords: CTAB; Hyaluronan; Polyelectrolyte-surfactant interactions; Surfactants; TTAB