title: Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients.
abstract: OBJECTIVE
  To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications.
  
  
  METHODS
  57 patients with focally increased FDG activity in bones and a definite follow up were included.
  
  
  RESULTS
  85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%.
  
  
  CONCLUSIONS
  Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.
authors.affiliation: Montefiore Medical Center, United States. Electronic address: ggarg@montefiore.org.
authors.forename: Gunjan
authors.initials: G
authors.lastname: Garg
authors.affiliation: Jacobi Medical Center, United States.
authors.forename: Raphaella
authors.initials: R
authors.lastname: DaSilva
authors.affiliation: Albert Einstein College of Medicine, United States.
authors.forename: Mimi
authors.initials: M
authors.lastname: Kim
authors.affiliation: Montefiore Medical Center, United States.
authors.forename: Charito
authors.initials: C
authors.lastname: Love
authors.affiliation: Montefiore Medical Center, United States.
authors.forename: Tony
authors.initials: T
authors.lastname: Abraham
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000000981:diagnostic imaging*; D000072078:Positron Emission Tomography Computed Tomography; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Bone metastases; CT correlate; FDG PET