title: Griscelli syndrome type-3.
abstract: Griscelli syndrome (GS) is a rare autosomal recessive multisystem disorder of pigmentary dilution of skin, silver gray hair, variable immunodeficiency, neurological impairment, and abnormal accumulation of melanosomes in melanocytes. GS type 3 is characterized by hypomelanosis with no immunological and neurological manifestation. Prognosis is very good in type 3 GS and usually require no active intervention, as opposed to type 1 and 2 where early diagnosis and treatment plays a crucial role in patient's survival. The characteristic phenotypic appearance, especially the pigment dilution of the patient's hair, is emphasized here.
authors.affiliation: Department of Dermatology, BJ Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
authors.forename: Bela J
authors.initials: BJ
authors.lastname: Shah
authors.affiliation: Department of Dermatology, BJ Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
authors.forename: Ashish K
authors.initials: AK
authors.lastname: Jagati
authors.affiliation: Department of Dermatology, BJ Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
authors.forename: Nilesh K
authors.initials: NK
authors.lastname: Katrodiya
authors.affiliation: Department of Dermatology, BJ Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
authors.forename: Sonal M
authors.initials: SM
authors.lastname: Patel
keywords: Griscelli syndrome; melanin clump; silvery gray hair