title: Microbial and endogenous metabolic conversions of rye phytochemicals.
abstract: Rye is one of the main cereals produced and consumed in the hemiboreal climate region. Due to its use primarily as wholegrain products, rye provides a rich source of dietary fibre as well as several classes of phytochemicals, bioactive compounds with potentially positive health implications. Here, we review the current knowledge of the metabolic pathways of phytochemical classes abundant in rye, starting from the microbial transformations occurring during the sourdough process and colonic fermentation and continuing with the endogenous metabolism. Additionally, we discuss the detection of specific metabolites by MS in different phases of their journey from the cereal to the target organs and excretion.
authors.affiliation: Institute of Public Health and Clinical Nutrition, , University of Eastern Finland, Kuopio, Finland.
authors.forename: Ville M
authors.initials: VM
authors.lastname: Koistinen
authors.affiliation: Institute of Public Health and Clinical Nutrition, , University of Eastern Finland, Kuopio, Finland.
authors.forename: Kati
authors.initials: K
authors.lastname: Hanhineva
mesh_terms: D001622:Betaine / Q000378:metabolism / Q000493:pharmacokinetics; D003106:Colon / Q000378:metabolism / Q000382:microbiology*; D005511:Food Handling; D005516:Food Microbiology; D006801:Humans; D064209:Phytochemicals / Q000378:metabolism / Q000493:pharmacokinetics*; D012434:Secale / Q000737:chemistry*
chemical_list: D064209:Phytochemicals; D001622:Betaine
keywords: Metabolism; Microbiota; Phytochemicals; Rye; Sourdough