title: Recent Advances in the Genetics of Hypertension.
abstract: Hypertension is a silent killer worldwide, caused by both genetic and environmental factors. Until now, genetic and genomic association studies of hypertension are reporting different degree of association on hypertension. Hence, it is essential to gather all the available information on the reported genetic loci and to determine if any biomarker(s) is/are significantly associated with hypertension. Current review concluded the potential biomarkers for hypertension, with regards to electrolyte and fluid transports, as well as sodium/potassium ions homeostasis, which are supported by the results of case-controls and meta-analyses.
authors.affiliation: Department of Biological Science, Faculty of Science, Universiti Tunku Abdul Rahman, Bandar Barat, 31900, Kampar, Perak, Malaysia. wynnelkw@gmail.com.
authors.forename: Loo Keat
authors.initials: LK
authors.lastname: Wei
authors.affiliation: Institute of Bioproduct Development and Department of Bioprocess Engineering, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81300, Skudai, Malaysia.
authors.forename: Anthony
authors.initials: A
authors.lastname: Au
authors.affiliation: Department of Biomedical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Jalan Universiti, Bandar Barat, 31900, Kampar, Perak, Malaysia.
authors.forename: Lai Kuan
authors.initials: LK
authors.lastname: Teh
authors.affiliation: Department of Agricultural and Food Science, Faculty of Science, Universiti Tunku Abdul Rahman, Jalan Universiti, Bandar Barat, 31900, Kampar, Perak, Malaysia.
authors.forename: Huey Shi
authors.initials: HS
authors.lastname: Lye
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000235:genetics*; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology; D010641:Phenotype; D011110:Polymorphism, Genetic; D012307:Risk Factors
chemical_list: D005819:Genetic Markers
keywords: GWAS; Genetic; Hypertension; Meta-analysis; Polymorphism