title: Antithyroid Arthritis Syndrome: A Case Report and Review of the Literature.
abstract: We herein report the case of a 38-year-old Japanese woman with antithyroid arthritis syndrome who experienced severe migratory polyarthritis after the initiation of thiamazole therapy. The patient's symptoms promptly disappeared without any sequelae after the withdrawal of the drug. Antithyroid arthritis syndrome is poorly characterized, and the findings from our literature review indicate that this syndrome exhibits serological features that are distinct from those of antithyroid agent-induced vasculitis syndrome. The absence of autoantibodies, especially anti-neutrophil cytoplasmic antibodies, may help characterize and diagnose antithyroid arthritis syndrome. Furthermore, physicians' awareness of this syndrome is essential for its diagnosis in clinical practice.
authors.affiliation: Division of Diabetes and Endocrinology, Japanese Red Cross Medical Center, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Takaya
authors.forename: Natsumi
authors.initials: N
authors.lastname: Kimura
authors.forename: Toru
authors.initials: T
authors.lastname: Hiyoshi
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology; D013956:Antithyroid Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001168:Arthritis / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006111:Graves Disease / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008713:Methimazole / Q000009:adverse effects* / Q000627:therapeutic use; D010666:Phenylpropionates / Q000627:therapeutic use; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D019268:Antibodies, Antineutrophil Cytoplasmic; D013956:Antithyroid Agents; D010666:Phenylpropionates; C040656:loxoprofen; D008713:Methimazole