title: Intestinal Lesion in a Dog Due to Cryptococcus gattii Type VGII and Review of Published Cases of Canine Gastrointestinal Cryptococcosis.
abstract: Cryptococcosis is a mycosis caused by yeasts of genus Cryptococcus, mainly the species C. neoformans and C. gattii that can affect humans and animals. These yeasts are widely distributed in the environment and are typically associated with avian droppings and decaying wood. Most infections are related to the respiratory tract, but the central nervous system and cutaneous lesions are also reported in the literature. The present report is a case of cryptococcosis in an 18-month-old unspayed female English Bulldog with the main complaint of weight loss and diarrhea. The presence of two large masses observed in an ultrasound examination leads us to perform an exploratory laparotomy. Considering the size of the lesion and the impossibility of owner to provide intensive care, the consent for euthanasia was requested. The postmortem diagnosis of cryptococcosis was revealed by cytological evaluation, and the involvement of C. gattii VGII was confirmed by isolation and identification tests as well as by the detection of the URA5 gene restriction fragment length polymorphism PCR analysis. Reports in the literature of the involvement of Cryptococcus in gastrointestinal lesions are rare in both human and veterinary medicine. Data about different forms of cryptococcosis are important to provide more knowledge of uncommon clinical presentations of this yeast and therefore improve the diagnoses and decisions for the best therapy.
authors.affiliation: Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil.
authors.forename: Daniel Paiva Barros
authors.initials: DPB
authors.lastname: de Abreu
authors.affiliation: Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil.
authors.forename: Carlos Henrique
authors.initials: CH
authors.lastname: Machado
authors.affiliation: Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil.
authors.forename: Mário Tatsuo
authors.initials: MT
authors.lastname: Makita
authors.affiliation: Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil.
authors.forename: Camila Flávia Magalhães
authors.initials: CFM
authors.lastname: Botelho
authors.affiliation: , Volta Redonda, Brazil.
authors.forename: Fernanda Gomes
authors.initials: FG
authors.lastname: Oliveira
authors.affiliation: Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil.
authors.forename: Cristiano Chaves Pessoa
authors.initials: CCP
authors.lastname: da Veiga
authors.affiliation: Centro de Parasitologia e Micologia, Instituto Adolfo Lutz, IAL, São Paulo, Brazil.
authors.forename: Marilena Dos Anjos
authors.initials: MDA
authors.lastname: Martins
authors.affiliation: Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil. baroni@ufrrj.br.
authors.forename: Francisco de Assis
authors.initials: FA
authors.lastname: Baroni
mesh_terms: D000818:Animals; D003453:Cryptococcosis / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D056285:Cryptococcus gattii / Q000302:isolation & purification*; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology*; D004285:Dogs; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*
keywords: Animal; Cryptococcus gattii; Dog; Gastrointestinal