title: Therapeutic management of acute uncomplicated diverticulitis.
abstract: Acute diverticulitis is a painful disease of the colon characterized by peridiverticular inflammation and/or infection. The spectrum of acute diverticulitis ranges from isolated peridiverticular inflammation all the way to free perforation with purulent or feculent peritonitis. Among gastrointestinal disorders, acute diverticulitis is one of the most common diagnoses in the ambulatory setting and principal hospital discharge diagnoses. Acute diverticulitis accounts for substantial utilization of healthcare resources and is a detriment to patients' quality of life. In the last decade, several cohort studies and trials have significantly improved our understanding of acute diverticulitis. This paper will review the current literature on acute uncomplicated diverticulitis with a focus on therapeutic management.
authors.affiliation: Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
authors.forename: Y Claire
authors.initials: YC
authors.lastname: Fan
authors.affiliation: Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, NC, USA - anne_peery@med.unc.edu.
authors.forename: Anne F
authors.initials: AF
authors.lastname: Peery
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D012809:Colon, Sigmoid / Q000601:surgery; D004239:Diverticulitis, Colonic / Q000175:diagnosis / Q000178:diet therapy / Q000453:epidemiology / Q000628:therapy*; D017558:Elective Surgical Procedures / Q000379:methods; D019317:Evidence-Based Medicine; D005765:Gastrointestinal Agents; D006801:Humans; D019804:Mesalamine / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D015995:Prevalence; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D012294:Rifamycins / Q000627:therapeutic use*; D000078262:Rifaximin; D012307:Risk Factors; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005765:Gastrointestinal Agents; D012294:Rifamycins; D019804:Mesalamine; D000078262:Rifaximin