title: Seasonal association between ambient ozone and mortality in Zhengzhou, China.
abstract: Different seasonal health effects of ambient ozone (O3) have been reported in previous studies. This might be due to inappropriate adjustment of temperature in different seasons. We used daily data on non-accidental mortality and ambient air pollution in Zhengzhou from January 19, 2013 to June 30, 2015. Season-stratified analyses using generalized additive models were conducted to evaluate the seasonal associations with adjustment of temperature with different lagged days (lag0-1 for warm season, lag0-14 for cold season). We recorded a total of 70,443 non-accidental deaths in Zhengzhou during the study period. Significant associations were observed between ambient O3and mortality in cold season. Every 10-μg/m3increment of 24-h O3of 1-day lagged time was associated with a 1.38% (95% CI 0.60, 2.16%) increase in all cause mortality, 1.35% (95% CI 0.41, 2.30%) increase in cardiovascular mortality, and 1.78% (95% CI 0.43, 3.14%) increase in respiratory mortality. Similar associations were observed when using daily 1- and 8-h maximum concentrations of O3. No significant association was found during warm season. This study suggests a more pronounced ozone-mortality association in cold season in Zhengzhou, and we suggest that different lagged temperatures should be considered when examining the seasonal health effects of ambient ozone.
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China.
authors.forename: Lijie
authors.initials: L
authors.lastname: Qin
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China. gujianqin1819@outlook.com.
authors.forename: Jianqin
authors.initials: J
authors.lastname: Gu
authors.affiliation: Science and Education Center, Zhengzhou Center for Disease Control and Prevention, Zhengzhou, China.
authors.forename: Shijie
authors.initials: S
authors.lastname: Liang
authors.affiliation: College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO, USA.
authors.forename: Fang
authors.initials: F
authors.lastname: Fang
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Bai
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Liu
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhao
authors.affiliation: Saint Louis University Hospital, Saint Louis, MO, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Walline
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China.
authors.forename: Shenglong
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China.|People's Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Cui
authors.affiliation: Henan Provincial People's Hospital, Zhengzhou, China.|People's Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Yaxin
authors.initials: Y
authors.lastname: Xu
authors.affiliation: Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China. linhualiang2002@163.com.
authors.forename: Hualiang
authors.initials: H
authors.lastname: Lin
mesh_terms: D000393:Air Pollutants / Q000032:analysis*; D000397:Air Pollution / Q000032:analysis; D002681:China / Q000453:epidemiology; D006801:Humans; D009026:Mortality; D009585:Nitrogen Dioxide / Q000032:analysis; D010126:Ozone / Q000032:analysis*; D052638:Particulate Matter / Q000032:analysis; D012621:Seasons; D013458:Sulfur Dioxide / Q000032:analysis
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter; D013458:Sulfur Dioxide; D010126:Ozone; D009585:Nitrogen Dioxide
keywords: Mortality; Ozone; Season; Temperature