title: New Synthesis of Gold- and Silver-Based Nano-Tetracycline Composites.
abstract: A new synthetic methodology of water-soluble gold and silver nanoparticles (AuNPs@TC and AgNPs@TC), using the antibiotic tetracycline (TC) as co-reducing and stabilizing agent, is reported. Both colloids exhibit high water stability. The average sizes obtained were 25±10 and 15±5 nm, respectively. Both composites were tested against TC-resistant bacteria, presenting an increasing antibacterial effect in the case of AgNPs@TC. The sensing towards metal ions was also explored. An interesting and reversible affinity of AuNPs@TC towards AlIIIcations in an aqueous system was also observed.
authors.affiliation: BIOSCOPE Group UCIBIO@REQUIMTE Chemistry Department, Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal; ProteoMass Scientific Society Faculty of Sciences and Technology University NOVA of Lisbon Madan Parque. Building VI. Office 232829-516 Monte da Caparica Portugal.
authors.forename: Jamila
authors.initials: J
authors.lastname: Djafari
authors.affiliation: Functional Genomics and Proteomics Unit Department of Genetics and Biotechnology University of Trás-os-Montes and Alto Douro 5000-801 Vila Real Portugal; Veterinary Science Department University of Trás-os-Montes and Alto Douro 5000-801 Vila Real Portugal; UCIBIO@REQUIMTE Chemistry Department Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal.
authors.forename: Catarina
authors.initials: C
authors.lastname: Marinho
authors.affiliation: Functional Genomics and Proteomics Unit Department of Genetics and Biotechnology University of Trás-os-Montes and Alto Douro 5000-801 Vila Real Portugal; Veterinary Science Department University of Trás-os-Montes and Alto Douro 5000-801 Vila Real Portugal; UCIBIO@REQUIMTE Chemistry Department Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal.
authors.forename: Tiago
authors.initials: T
authors.lastname: Santos
authors.affiliation: Functional Genomics and Proteomics Unit Department of Genetics and Biotechnology University of Trás-os-Montes and Alto Douro 5000-801 Vila Real Portugal; UCIBIO@REQUIMTE Chemistry Department Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal.
authors.forename: Gilberto
authors.identifier: 0000-0002-6365-0735
authors.initials: G
authors.lastname: Igrejas
authors.affiliation: Department of Food and Agriculture, Biochemistry and Molecular Biology University of La Rioja (UR) 26006 Logroño Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Torres
authors.affiliation: BIOSCOPE Group UCIBIO@REQUIMTE Chemistry Department, Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal; ProteoMass Scientific Society Faculty of Sciences and Technology University NOVA of Lisbon Madan Parque. Building VI. Office 232829-516 Monte da Caparica Portugal.
authors.forename: José Luis
authors.identifier: 0000-0001-6276-8507
authors.initials: JL
authors.lastname: Capelo
authors.affiliation: Veterinary Science Department University of Trás-os-Montes and Alto Douro 5000-801 Vila Real Portugal; UCIBIO@REQUIMTE Chemistry Department Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal.
authors.forename: Patricia
authors.identifier: 0000-0003-0925-689X
authors.initials: P
authors.lastname: Poeta
authors.affiliation: BIOSCOPE Group UCIBIO@REQUIMTE Chemistry Department, Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal; ProteoMass Scientific Society Faculty of Sciences and Technology University NOVA of Lisbon Madan Parque. Building VI. Office 232829-516 Monte da Caparica Portugal.
authors.forename: Carlos
authors.identifier: 0000-0001-5582-5446
authors.initials: C
authors.lastname: Lodeiro
authors.affiliation: BIOSCOPE Group UCIBIO@REQUIMTE Chemistry Department, Faculty of Science and Technology University NOVA of Lisbon 2829-516 Monte da Caparica Portugal; ProteoMass Scientific Society Faculty of Sciences and Technology University NOVA of Lisbon Madan Parque. Building VI. Office 232829-516 Monte da Caparica Portugal.
authors.forename: Javier
authors.identifier: 0000-0001-8853-2631
authors.initials: J
authors.lastname: Fernández-Lodeiro
keywords: aluminum detection; antimicrobial studies; gold and silver nanoparticles; nanoantibiotics; nanochemical sensor