title: Magnetic Resonance Enterography in 300 Known Cases of Crohn's Disease: An Initial Report from a Referral Center in Iran.
abstract: BACKGROUND Magnetic resonance enterography (MRE) has become the modality of choice in assessment of patients with Crohn's disease (CD). We aimed to present our experience on 300 patients with CD who underwent MRE during the first 30 months after setting up MRE for the first time in a referral center in Iran. METHODS Patients with a definite diagnosis of CD based on either ileocolonoscopy or histopathological studies were included in the final report and categorized into four phenotypes of inactive, active, stricturing, and penetrating disease. RESULTS This was a case series study on 300 patients with known CD out of 594 referred subjects. The most prevalent phenotype was inactive observed in 162 (54.0%) patients followed by stricturing in 44 (14.7%), active in 40 (13.3%), penetrating in 27(9%), and active on chronic in 27 (9%) cases. The number of referred patients increased from 51 cases in the first 6 months to 165 in the last 6 months. CONCLUSION This study presents the first report on the application of MRE in Iran as superb modality for management of CD. The growing number of referred patients indicates that MRE has been successful in addressing the most critical concerns of clinicians on determining the dominant disease phenotype.
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Amir Reza
authors.initials: AR
authors.lastname: Radmard
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Sepehr
authors.initials: S
authors.lastname: Haghighi
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Amir Pejman
authors.initials: AP
authors.lastname: Hashemi Taheri
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Payam
authors.initials: P
authors.lastname: Mohammadinejad
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Rana
authors.initials: R
authors.lastname: Eftekhar Vaghefi
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Sara
authors.initials: S
authors.lastname: Naybandi Atashi
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Neda
authors.initials: N
authors.lastname: Pak
authors.affiliation: Department of Radiology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Leila
authors.initials: L
authors.lastname: Aghaghazvini
authors.affiliation: Autoimmune and Motility Disorders of the Gastro-Intestinal Tract Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Malekzadeh
keywords: Crohn’s Disease; Diagnosis; Iran; Magnetic Resonance Enterography