title: Association between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia in elderly Korean males: The Korean National Health and Nutrition Examination Survey.
abstract: BACKGROUND
  We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males.
  
  
  METHODS
  We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥60years who participated in the 2010-2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight (%), which is >1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤1.4, Q2: 1.5-2.4, Q3: 2.5-3.8 and Q4: ≥3.9) after adjusting for confounding variables.
  
  
  RESULTS
  The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95% CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12-3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity.
  
  
  CONCLUSIONS
  TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Severance check-up, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; Department of Medicine, Graduate School, Yonsei University, Seoul, Republic of Korea.
authors.forename: Tae-Ha
authors.initials: TH
authors.lastname: Chung
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Yu-Jin
authors.initials: YJ
authors.lastname: Kwon
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Jae-Yong
authors.initials: JY
authors.lastname: Shim
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: ukyjhome@yuhs.ac.
authors.forename: Yong-Jae
authors.initials: YJ
authors.lastname: Lee
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood*; D003430:Cross-Sectional Studies; D006801:Humans; D008297:Male; D009749:Nutrition Surveys; D056910:Republic of Korea; D055948:Sarcopenia / Q000097:blood / Q000209:etiology*; D014280:Triglycerides / Q000097:blood*
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; D014280:Triglycerides
keywords: Elderly males; Insulin resistance; Sarcopenia; TG/HDL ratio