title: Live birth in a 46-year-old woman using microdose GnRH agonist flare-up protocol combined with GnRH antagonist: a case report.
abstract: Few successful pregnancies after age 45 years with low ovarian reserve have been reported. We report a 46-year-old woman with basal FSH 20.36 mIU/mL and an antral follicle count of four obtained two embryos and delivered a healthy infant with IVF using a microdose GnRH-a flare-up protocol combined with GnRH-ant.
authors.affiliation: Reproductive and Genetic Hospital of CITIC-Xiangya Changsha China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Institute of Reproductive and Stem Cell Engineering School of basic medicine Central South University Changsha China; Key Laboratory of Reproductive and Stem Cell Engineering Ministry of Health Changsha China.
authors.forename: Ya-Qiong
authors.initials: YQ
authors.lastname: Liu
authors.affiliation: Reproductive and Genetic Hospital of CITIC-Xiangya Changsha China; Key Laboratory of Reproductive and Stem Cell Engineering Ministry of Health Changsha China.
authors.forename: Guang-Xiu
authors.initials: GX
authors.lastname: Lu
authors.affiliation: Reproductive and Genetic Hospital of CITIC-Xiangya Changsha China; Institute of Reproductive and Stem Cell Engineering School of basic medicine Central South University Changsha China; Key Laboratory of Reproductive and Stem Cell Engineering Ministry of Health Changsha China.
authors.forename: Fei
authors.initials: F
authors.lastname: Gong
keywords: Advanced maternal age; GnRH agonist; GnRH antagonist; ovarian stimulation; poor responder