title: Laparoscopic kidney biopsy in dogs: Comparison of cup forceps and core needle biopsy.
abstract: OBJECTIVE
  To investigate the feasibility of laparoscopic kidney biopsy with cup biopsy forceps in dogs (CupBF), and to compare to the use of a core biopsy needle (CoreBN).
  
  
  METHODS
  Experimental; randomized, controlled design.
  
  
  METHODS
  Eight healthy, adult Beagle dogs.
  
  
  METHODS
  Dogs were randomized to undergo laparoscopic biopsy of the right kidney using either 5 mm CupBF or a 16 gauge CoreBN. Intraoperative hemorrhage of the biopsy site was monitored. Biopsy quality was evaluated for tissue fragmentation and crushing, presence of renal cortex with or without medulla, and number of glomeruli. Postoperative packed cell volume, urinalysis, and ultrasonographic appearance of the biopsy site were evaluated.
  
  
  RESULTS
  Biopsy specimens were obtained by both techniques and reliable hemostasis was achieved with direct compression in all dogs. The histologic score for CupBF biopsies was not significantly different from CoreBN biopsies. One CoreBN biopsy contained both renal cortex and medullar, while all CupBF biopsies contained cortex only. The mean (SD) number of glomeruli was significantly higher in CupBF biopsies [60 (9.1)] than CoreBN biopsies [26 (4.3)]. There was no gross hematuria, perirenal hematoma, or hydronephrosis in any dog postoperative.
  
  
  CONCLUSIONS
  Laparoscopic kidney biopsy in dogs using 5 mm cup biopsy forceps is feasible with minimal risk and more glomeruli obtained compared to laparoscopic kidney biopsy using 16 gauge core biopsy needles.
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
authors.forename: Jiyoung
authors.initials: J
authors.lastname: Park
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
authors.forename: Jinwoo
authors.initials: J
authors.lastname: Lee
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
authors.forename: Hae-Beom
authors.initials: HB
authors.lastname: Lee
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
authors.forename: Seong Mok
authors.initials: SM
authors.lastname: Jeong
mesh_terms: D000818:Animals; D062005:Biopsy, Large-Core Needle / Q000295:instrumentation / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D006470:Hemorrhage / Q000097:blood / Q000517:prevention & control / Q000652:urine; D007674:Kidney Diseases / Q000175:diagnosis / Q000662:veterinary*; D010535:Laparoscopy; D008297:Male