title: [Status of seroepidemiology of hepatitis A, B and C in primary and middle school students in Shufu county, Xinjiang Uygur Autonomous Region of China].
abstract: Objective:To explore the status of seroepidemiology on hepatitis A, B and C in primary and middle school students in Shufu county, Xinjiang Uygur Autonomous Region of China (Xinjiang) and to evaluate the effect of related immunization.Methods:Students in four towns and villages were selected by cluster random sampling method. HAV-IgG, HBsAg, HBsAb and HCV-IgG were detected in Feb to May, 2015.Results:The overall HAV-IgG positive rate was 99.75%, among 4 830 primary and middle school students. The positive rates were seen 99.92% in boys and 99.57% in girls, with difference statistically significant (χ2=5.798,P=0.016). The overall HBsAg positive rate appeared as 3.02%, with 3.55% for boys and 2.47% for girls, with difference statistically significant (χ2=4.782,P=0.029). The difference between age specific HBsAg positive rates also showed statistically significant (χ2=71.990,P=0.000). HBsAg positive rate in the students in rural area (3.28%) was higher than that in the students in urban area (1.61%,χ2=6.019,P=0.014). HBsAb positive rate was 38.84%, and the differences between the age specific HBsAb positive rates appeared statistically significant (χ2=837.699,P=0.000). HBsAg positive rate in students from the urban area (42.36%) was higher than those from the rural area (38.20%,χ2=4.598,P=0.032). 2 815 students, accounting for 58.28% of the total students, showed negative on both HBsAg and HBsAb. The overall HCV-IgG positive rate was 0.19%, and all appeared in students from the rural areas, with ethnicity solely as Uygur.Conclusions:The effect of hepatitis A vaccine was satisfactory in primary and middle school students in Shufu county but quiet a number of the students missed the vaccination. The infection rate of hepatitis C was low. Publicity and health education on hepatitis immunization and control should be revved up. Programs regarding primary and supplementary immunization on hepatitis, should be carried out timely for children of school age.
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
authors.forename: Z B
authors.initials: ZB
authors.lastname: Zhang
authors.affiliation: Department of Immunization Program Planning, Shufu Center for Disease Control and Prevention, Kashi 844100, China.
authors.forename: Z X
authors.initials: ZX
authors.lastname: Xue
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
authors.forename: Z G
authors.initials: ZG
authors.lastname: Han
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
authors.forename: Q Y
authors.initials: QY
authors.lastname: Yang
authors.affiliation: Office, Shufu Health Centre for Women and Children, Kashi 844100, China.
authors.forename: X R
authors.initials: XR
authors.lastname: Zheng
authors.affiliation: Office, Shufu Health Centre for Women and Children, Kashi 844100, China.
authors.forename: Tuerhong
authors.initials: T
authors.lastname: Zulipikaer
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
authors.forename: M
authors.initials: M
authors.lastname: Wang
mesh_terms: D002681:China; D005260:Female; D006506:Hepatitis A; D022362:Hepatitis A Vaccines; D006509:Hepatitis B; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006526:Hepatitis C; D006801:Humans; D008297:Male; D012574:Schools; D016036:Seroepidemiologic Studies; D013334:Students; D014611:Vaccination
chemical_list: D022362:Hepatitis A Vaccines; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens