title: Recent Advances in Inorganic Nanoparticle-Based NIR Luminescence Imaging: Semiconductor Nanoparticles and Lanthanide Nanoparticles.
abstract: Several types of nanoparticle-based imaging probes have been developed to replace conventional luminescent probes. For luminescence imaging, near-infrared (NIR) probes are useful in that they allow deep tissue penetration and high spatial resolution as a result of reduced light absorption/scattering and negligible autofluorescence in biological media. They rely on either an anti-Stokes or a Stokes shift process to generate luminescence. For example, transition metal-doped semiconductor nanoparticles and lanthanide-doped inorganic nanoparticles have been demonstrated as anti-Stokes shift-based agents that absorb NIR light through two- or three-photon absorption process and upconversion process, respectively. On the other hand, quantum dots (QDs) and lanthanide-doped nanoparticles that emit in NIR-II range (∼1000 to ∼1350 nm) were suggested as promising Stokes shift-based imaging agents. In this topical review, we summarize and discuss the recent progress in the development of inorganic nanoparticle-based luminescence imaging probes working in NIR range.
authors.affiliation: Center for Nanoparticle Research, Institute for Basic Science (IBS) , Seoul 08826, Republic of Korea.
authors.forename: Dokyoon
authors.initials: D
authors.lastname: Kim
authors.affiliation: School of Advanced Materials Engineering, Kookmin University , Seoul 02707, Republic of Korea.
authors.forename: Nohyun
authors.initials: N
authors.lastname: Lee
authors.affiliation: School of Chemical Engineering, Chonnam National University , Gwangju 61186, Republic of Korea.
authors.forename: Yong Il
authors.identifier: 0000-0003-3167-4908
authors.initials: YI
authors.lastname: Park
authors.affiliation: Center for Nanoparticle Research, Institute for Basic Science (IBS) , Seoul 08826, Republic of Korea.|School of Chemical and Biological Engineering, Seoul National University , Seoul 08826, Republic of Korea.
authors.forename: Taeghwan
authors.initials: T
authors.lastname: Hyeon
mesh_terms: D007287:Inorganic Chemicals / Q000737:chemistry*; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D012666:Semiconductors; D019265:Spectroscopy, Near-Infrared
chemical_list: D007287:Inorganic Chemicals; D028581:Lanthanoid Series Elements