title: How do you decide on hormone replacement therapy in women with risk of venous thromboembolism?
abstract: Women are increasingly encouraged to participate in making decisions about hormone replacement therapy (HRT). In postmenopausal women with severe vasomotor symptoms, HRT can significantly improve the quality of life. However, the use of HRT may also increase the risk of venous thromboembolism (VTE), the risk which depends of both treatment-related and patient-related factors. This review summarizes some important points about the selection of the safest hormonal replacement modality in women with a history of VTE and management of VTE risks in postmenopausal women wishing to take HRT.
authors.affiliation: Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia; Medical Faculty, University of Belgrade, Belgrade, Serbia. Electronic address: danijela.lekovic@yahoo.com.
authors.forename: Danijela
authors.initials: D
authors.lastname: Lekovic
authors.affiliation: Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia; Medical Faculty, University of Belgrade, Belgrade, Serbia. Electronic address: predragmiljic@yahoo.com.
authors.forename: Predrag
authors.initials: P
authors.lastname: Miljic
authors.affiliation: Clinic of Obstetrics and Gynecology, Clinical Center Serbia, Belgrade, Serbia. Electronic address: drdmitrovic@gmail.com.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Dmitrovic
authors.affiliation: Department of Haematology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom. Electronic address: Jecko.Thachil@cmft.nhs.uk.
authors.forename: Jecko
authors.initials: J
authors.lastname: Thachil
mesh_terms: D001777:Blood Coagulation / Q000187:drug effects; D000066491:Clinical Decision-Making; D004347:Drug Interactions; D004967:Estrogens / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D017698:Postmenopause; D018570:Risk Assessment; D012307:Risk Factors; D054556:Venous Thromboembolism / Q000097:blood / Q000453:epidemiology / Q000209:etiology*
chemical_list: D004967:Estrogens
keywords: Hormone replacement therapy; Menopause; Venous thromboembolism