title: Radical Route to 1,4-Benzothiazine Derivatives from 2-Aminobenzenethiols and Ketones under Transition-Metal-Free Conditions.
abstract: Transition-metal-free radical access to 1,4-benzothiazine derivatives from o-aminobenzenethiols is disclosed. This procedure is available for various ketones including α,β-unsaturated, cyclic, linear, and fluoroalkyl ketones to generate a number of 1,4-benzothiazines, which exist in numerous bioactive and natural molecules, rendering this protocol attractive to both synthetic and medicinal chemistry.
authors.affiliation: Chemical Engineering College, Nanjing University of Science and Technology , Nanjing 210094, China.
authors.forename: Ya-Mei
authors.initials: YM
authors.lastname: Lin
authors.affiliation: Chemical Engineering College, Nanjing University of Science and Technology , Nanjing 210094, China.
authors.forename: Guo-Ping
authors.initials: GP
authors.lastname: Lu
authors.affiliation: Chemical Engineering College, Nanjing University of Science and Technology , Nanjing 210094, China.
authors.forename: Rong-Kang
authors.initials: RK
authors.lastname: Wang
authors.affiliation: Chemical Engineering College, Nanjing University of Science and Technology , Nanjing 210094, China.
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Yi