title: Enantioselective Oxidative Homocoupling and Cross-Coupling of 2-Naphthols Catalyzed by Chiral Iron Phosphate Complexes.
abstract: Novel chiral iron phosphate complexes were prepared as catalysts for asymmetric oxidative coupling reactions. These catalysts were applied for the synthesis of enantio-enriched C1- and C2-symmetric BINOLs, in which the 3 and 3' positions are available for chemical modifications. It was proposed that the reaction takes place via an oxidative radical-anion coupling mechanism. A destructive BINOL racemization that competes with the enantioselective oxidative coupling of 2-naphthols was revealed, thereby offering new insights into this highly important reaction.
authors.affiliation: Department of Chemistry, Ben-Gurion University of the Negev , Beer-Sheva 84105, Israel.
authors.forename: Sachin
authors.initials: S
authors.lastname: Narute
authors.affiliation: Department of Chemistry, Ben-Gurion University of the Negev , Beer-Sheva 84105, Israel.
authors.forename: Regev
authors.initials: R
authors.lastname: Parnes
authors.affiliation: Department of Chemistry, University of California , Berkeley, California 94720, United States.
authors.forename: F Dean
authors.initials: FD
authors.lastname: Toste
authors.affiliation: Department of Chemistry, Ben-Gurion University of the Negev , Beer-Sheva 84105, Israel.
authors.forename: Doron
authors.identifier: 0000-0002-8363-8709
authors.initials: D
authors.lastname: Pappo