title: Comparison of Extended-Spectrumβ-Lactamase-ProducingEscherichia coliIsolates from Drinking Well Water and Pit Latrine Wastewater in a Rural Area of China.
abstract: The present study was conducted to gain insights into the occurrence and characteristics of extended-spectrum beta-lactamase- (ESBL-) producingEscherichia coli(E. coli) from drinking well water in the rural area of Laiwu, China, and to explore the role of the nearby pit latrine as a contamination source. ESBL-producingE. colifrom wells were compared with isolates from pit latrines in the vicinity. The results showed that ESBL-producingE. coliisolates, with the same antibiotic resistance profiles, ESBL genes, phylogenetic group, plasmid replicon types, and enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) fingerprints, were isolated from well water and the nearby pit latrine in the same courtyard. Therefore, ESBL-producingE. coliin the pit latrine may be a likely contributor to the presence of ESBL-producingE. coliin rural well water.
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271000, China.
authors.forename: Hongna
authors.identifier: 0000-0003-4543-6097
authors.initials: H
authors.lastname: Zhang
authors.affiliation: College of Life Sciences, Taishan Medical University, Tai'an 271000, China.
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Gao
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271000, China.
authors.forename: Weishan
authors.identifier: 0000-0003-4812-5921
authors.initials: W
authors.lastname: Chang
mesh_terms: D015373:Bacterial Typing Techniques; D002681:China; D060766:Drinking Water / Q000382:microbiology*; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification*; D005798:Genes, Bacterial; D006801:Humans; D010802:Phylogeny; D012424:Rural Population; D014038:Toilet Facilities; D014871:Water Microbiology; D060986:Water Wells; D018440:beta-Lactam Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics
chemical_list: D060766:Drinking Water; D001618:beta-Lactamases