title: Methylome evolution in plants.
abstract: Despite major progress in dissecting the molecular pathways that control DNA methylation patterns in plants, little is known about the mechanisms that shape plant methylomes over evolutionary time. Drawing on recent intra- and interspecific epigenomic studies, we show that methylome evolution over long timescales is largely a byproduct of genomic changes. By contrast, methylome evolution over short timescales appears to be driven mainly by spontaneous epimutational events. We argue that novel methods based on analyses of the methylation site frequency spectrum (mSFS) of natural populations can provide deeper insights into the evolutionary forces that act at each timescale.
authors.affiliation: Population Epigenetics and Epigenomics, Technical University of Munich, Liesel-Beckman-Str. 2, 85354, Freising, Germany.
authors.forename: Amaryllis
authors.initials: A
authors.lastname: Vidalis
authors.affiliation: Population Genetics, Technical University of Munich, Liesel-Beckman-Str. 2, 85354, Freising, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Živković
authors.affiliation: Groningen Bioinformatics Centre, University of Groningen, 9747 AG, Groningen, The Netherlands.
authors.forename: René
authors.initials: R
authors.lastname: Wardenaar
authors.affiliation: Population Epigenetics and Epigenomics, Technical University of Munich, Liesel-Beckman-Str. 2, 85354, Freising, Germany.
authors.forename: David
authors.initials: D
authors.lastname: Roquis
authors.affiliation: Population Genetics, Technical University of Munich, Liesel-Beckman-Str. 2, 85354, Freising, Germany. tellier@wzw.tum.de.
authors.forename: Aurélien
authors.initials: A
authors.lastname: Tellier
authors.affiliation: Population Epigenetics and Epigenomics, Technical University of Munich, Liesel-Beckman-Str. 2, 85354, Freising, Germany. frank@johanneslab.org.|Institute for Advanced Study, Technical University of Munich, Lichtenbergstr. 2a, 85748, Garching, Germany. frank@johanneslab.org.
authors.forename: Frank
authors.initials: F
authors.lastname: Johannes
mesh_terms: D017360:Arabidopsis / Q000235:genetics; D019175:DNA Methylation / Q000235:genetics*; D019143:Evolution, Molecular; D018506:Gene Expression Regulation, Plant; D014644:Genetic Variation; D018745:Genome, Plant