title: Two Atypical Cases of Nodular Gastritis: A Poorly Differentiated Gastric Adenocarcinoma and a Pseudo-Low Grade Gastric MALT Lymphoma.
abstract: Nodular gastritis is aHelicobacter pylori-related gastritis with endoscopically proven gooseflesh skin-like nodularity in the gastric antrum. Although an association between nodular gastritis and gastric malignancies has been suggested, there is neither a treatment strategy nor a treatment guideline for this condition because of its relative rarity. We have recently experienced two cases of diffuse-type nodular gastritis invading both the antrum and corpus of the stomach with atypical findings that required specific treatments in two young females. The first patient was diagnosed with a suspicious low grade gastric mucosa associated lymphoid tissue (MALT) lymphoma lesion on a diffuse-type nodular gastritis, and was cured byH. pylorieradication. The second patient was diagnosed with a signet cell type gastric cancer on a diffuse-type nodular gastritis, and was cured by surgical resection. When considering the nature and significance of these gastric lesions, a link between nodular gastritis and gastric malignancy should be considered, especially in young women who have diffuse-type nodular gastritis involving both the antrum and corpus of the stomach.
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Hye Jin
authors.initials: HJ
authors.lastname: Choi
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Jung Hyun
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Dong Choon
authors.initials: DC
authors.lastname: Seol
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: So Young
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Hae Jin
authors.initials: HJ
authors.lastname: Choi
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Hyun Sik
authors.initials: HS
authors.lastname: Park
authors.affiliation: Departments of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Sung Noh
authors.initials: SN
authors.lastname: Hong
authors.affiliation: Departments of Pathology, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Hye Seung
authors.initials: HS
authors.lastname: Han
keywords: Gastric cancer; Gastric mucosa associated lymphoid tumor; Helicobacter pylori; Nodular gastritis