title: Buttressing Salicylaldehydes: A Multipurpose Directing Group for C(sp3)-H Bond Activation.
abstract: A palladium-catalyzed reaction of primary amines with iodoarenes produces γ-arylated primary amines. A bulky salicylaldehyde, which is marked as easily available, installable, removable, and recoverable, plays a key role in directing palladium to site-selectively activate the C-H bond located γ to the amino group.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.|Interdisciplinary Research Center for Catalytic Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan.
authors.forename: Akira
authors.identifier: 0000-0002-0379-792X
authors.initials: A
authors.lastname: Yada
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.
authors.forename: Wenqing
authors.initials: W
authors.lastname: Liao
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Sato
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami
keywords: C−H activation; amines; arylation; palladium; reaction mechanisms