title: Relationship Between Carotid Stenosis and Infarct Volume in Ischemic Stroke Patients.
abstract: BACKGROUND Stroke is a serious health problem all over the world. Ischemia causes 85% of strokes and 75% of these ischemic strokes occur within the area supplied by the internal carotid artery (ICA). MATERIAL AND METHODS This study included 47 acute stroke patients who were in the large-artery atherosclerosis group according to Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification and who had an infarct in the area supplied by the internal carotid artery. We sought to determine whether there was a significant correlation between the infarct volume of the patients as measured by diffusion-weighted magnetic resonance imaging (DW MRI), their National Institutes of Health Stroke Scale (NIHSS), and degree of carotid stenosis as identified by carotid computed tomography angiography (CTA). RESULTS A significant correlation was observed between the percentage of carotid artery stenosis and infarct volume (p<0.001). In addition, there was a significant positive correlation between the NIHSS and infarct volume; the correlation was of moderate strength (r=0.366, p=0.001). CONCLUSIONS Our findings indicate that the percentage of carotid artery stenosis could be useful in predicting the infarct volume of the stroke.
authors.affiliation: Department of Neurology, Sakarya University, Faculty of Medicine, Sakarya, Turkey.
authors.forename: Aybala Neslihan
authors.initials: AN
authors.lastname: Alagoz
authors.affiliation: Department of Neurology, Sakarya University, Faculty of Medicine, Sakarya, Turkey.
authors.forename: Bilgehan Atılgan
authors.initials: BA
authors.lastname: Acar
authors.affiliation: Department of Neurology, Sakarya University, Faculty of Medicine, Sakarya, Turkey.
authors.forename: Türkan
authors.initials: T
authors.lastname: Acar
authors.affiliation: Department of Radiology, Sakarya University, Faculty of Medicine, Sakarya, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Karacan
authors.affiliation: Department of Neurology, Sakarya University, Faculty of Medicine, Sakarya, Turkey.
authors.forename: Bekir Enes
authors.initials: BE
authors.lastname: Demiryürek
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D002545:Brain Ischemia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000503:physiopathology; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002544:Cerebral Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000000981:diagnostic imaging* / Q000503:physiopathology