title: The diagnostic value of serum pentraxin 3 levels in pulmonary contusion.
abstract: OBJECTIVE
  To investigate the difference in pentraxin 3 (PTX 3) levels between patients with pulmonary contusion and healthy volunteers.
  
  
  METHODS
  This study was conducted with a group of 20 trauma patients diagnosed with pulmonary contusion and 30 healthy individuals enrolled as a control group in a tertiary university hospital.
  
  
  RESULTS
  Median PTX 3 levels were 7.05 (3.29-13.1), ng/ml in the contusion group and 1.03 (0.7-1.58) ng/ml in the control group. PTX 3 titers were significantly higher in patients with pulmonary contusion compared to those of the control group (p<0.001). An area under the curve (AUC) value of 0.968 investigated using ROC analysis to determine the diagnostic value of the PTX-3 in pulmonary contusion patients was measured. A PTX-3 cut-off value of 2.06 produced 95.5% sensitivity and 86.7% specificity.
  
  
  CONCLUSIONS
  PTX 3 levels in pulmonary contusion increased significantly compared to the healthy control group. If supported by wider series, PTX 3 may be expected to be capable of use as a marker in pulmonary contusion.
authors.affiliation: Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey. Electronic address: dr.ozgurtatli@gmail.com.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Tatli
authors.affiliation: Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey.
authors.forename: Nur Banu Keha
authors.initials: NB
authors.lastname: Kurt
authors.affiliation: Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey.
authors.forename: Yunus
authors.initials: Y
authors.lastname: Karaca
authors.affiliation: Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey.
authors.forename: Aynur
authors.initials: A
authors.lastname: Sahin
authors.affiliation: Ordu University, Training and Research Hospıtal, Turkey; Department of Emergency Medicine, Ordu, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Aygün
authors.affiliation: Karadeniz Technical University, Faculty of Medicine, Department of Medical Biochemistry, Trabzon, Turkey.
authors.forename: Elif
authors.initials: E
authors.lastname: Sahin
authors.affiliation: Ankara Training and Research Hospital, Department of Emergency Medicine, Ankara, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Katipoglu
authors.affiliation: Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey.
authors.forename: Umut
authors.initials: U
authors.lastname: Eryigit
authors.affiliation: Acıbadem University, Faculty of Medicine, Department of Emergency Medicine, İstanbul, Turkey.
authors.forename: Suha
authors.initials: S
authors.lastname: Turkmen
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000032:analysis*; D016022:Case-Control Studies; D003288:Contusions / Q000097:blood / Q000175:diagnosis; D006801:Humans; D055370:Lung Injury / Q000097:blood* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012372:ROC Curve; D012680:Sensitivity and Specificity; D000683:Serum Amyloid P-Component / Q000032:analysis*; D014421:Turkey; D000099153:Pentraxins
chemical_list: D002097:C-Reactive Protein; D000683:Serum Amyloid P-Component; D000099153:Pentraxins
keywords: Inflammation; Pentraxin 3; Pulmonary contusion