title: Investigating Simulated Driving Errors in Amnestic Single- and Multiple-Domain Mild Cognitive Impairment.
abstract: The areas of driving impairment characteristic of mild cognitive impairment (MCI) remain unclear. This study compared the simulated driving performance of 24 individuals with MCI, including amnestic single-domain (sd-MCI, n = 11) and amnestic multiple-domain MCI (md-MCI, n = 13), and 20 age-matched controls. Individuals with MCI committed over twice as many driving errors (20.0 versus 9.9), demonstrated difficulty with lane maintenance, and committed more errors during left turns with traffic compared to healthy controls. Specifically, individuals with md-MCI demonstrated greater driving difficulty compared to healthy controls, relative to those with sd-MCI. Differentiating between different subtypes of MCI may be important when evaluating driving safety.
authors.affiliation: Neuroscience Research Program, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.|Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
authors.forename: Megan A
authors.initials: MA
authors.lastname: Hird
authors.affiliation: Neuroscience Research Program, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.|Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
authors.forename: Kristin A
authors.initials: KA
authors.lastname: Vesely
authors.affiliation: Neuroscience Research Program, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.|Department of Psychiatry, Division of Geriatric Psychiatry, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
authors.forename: Corinne E
authors.initials: CE
authors.lastname: Fischer
authors.affiliation: Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada.|Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Graham
authors.affiliation: Department of Medicine and Rotman Research Institute, Baycrest Health Science, Toronto, ON, Canada.|Department of Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.|Department of Research, Toronto Rehabilitation Institute - University Health Network, Toronto, ON, Canada.
authors.forename: Gary
authors.initials: G
authors.lastname: Naglie
authors.affiliation: Neuroscience Research Program, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.|Department of Surgery, Neurosurgery Division, University of Toronto, Toronto, ON, Canada.|Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
authors.forename: Tom A
authors.initials: TA
authors.lastname: Schweizer
mesh_terms: D001334:Automobile Driving; D060825:Cognitive Dysfunction / Q000145:classification* / Q000523:psychology*; D003198:Computer Simulation; D006801:Humans
keywords: Automobile driving; cognition; computer simulation patient outcome assessment; mild cognitive impairment