title: A new function for miRNAs as regulators of autophagy.
abstract: Autophagy is a self-digestive process regulated by an intricate network of factors able either to ensure the prosurvival function of autophagy or to convert it in a death pathway. Recently, the involvement of miRNAs in the regulation of autophagy networks has been reported. This review will summarize the main features of these small noncoding endogenous RNAs, focusing on their relevance in cancer and finally addressing their impact on autophagy.
authors.affiliation: Istituto di Genetica Molecolare CNR, Via Abbiategrasso 207, 27100 Pavia, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Aredia
authors.affiliation: Istituto di Genetica Molecolare CNR, Via Abbiategrasso 207, 27100 Pavia, Italy.
authors.forename: Anna Ivana
authors.initials: AI
authors.lastname: Scovassi
mesh_terms: D000818:Animals; D001343:Autophagy / Q000235:genetics*; D006801:Humans; D035683:MicroRNAs / Q000378:metabolism*; D009369:Neoplasms / Q000235:genetics* / Q000473:pathology*
chemical_list: D035683:MicroRNAs
keywords: antagomir; autophagy; biomarker; cancer; miRNA; oncomiR; tumor suppressor miRNA