title: Palatability and Clinical Effects of an Oral Recuperation Fluid During the Recovery of Dogs With Suspected Parvoviral Enteritis.
abstract: Dogs infected with canine parvovirus (CPV) can develop severe enteritis that requires supportive care until voluntary food and water consumption return. An oral recuperation fluid (ORF) may assist in the overall recovery from CPV. The hypotheses of the study were that dogs with naturally infected CPV would prefer the ORF to water and that dogs consuming the ORF would have a more rapid return to voluntary appetite and improved caloric intake during the initial recovery period compared with dogs consuming water. A total of 28 dogs with CPV were enrolled. Dogs were excluded if voluntary food or water intake was present at the time of study enrollment. Dogs were randomized to either an ORF or water group. The designated fluid was offered twice daily, followed by offering the opposite fluid 1 hour later if the designated fluid was refused. Dogs also received a standardized supportive treatment protocol. Beginning on day 2, all dogs were offered a gastrointestinal diet q8h, staggered with the fluid intake trials. A total of 40% (6/15) of dogs with CPV consumed the ORF as their designated fluid, and 31% (4/13) of dogs with CPV consumed water as their designated fluid (P = .71). For those dogs who refused their designated fluid, 56% (5/9) of the dogs consuming ORF ultimately consumed water, and 22% (2/9) of the dogs consuming water also consumed the ORF (P = .33). Dogs who consumed the ORF demonstrated a more rapid return to voluntary appetite (median = 1.5 days [range: 1-3]) compared with those that consumed water (median = 4.25 days [range: 1.5-5.5], P = .01) or neither fluid (median = 2 days [range: 1.5-5.5], P = .03). Additionally, those dogs consuming the ORF demonstrated greater caloric intake [median = 100% resting energy requirement (RER), range: 61%-100%] compared with those that consumed water (median = 19% RER; range: 9%-100%; P = .004) or neither fluid (median = 37% RER; range: 3-100; P = .05). This study suggests that some dogs with CPV voluntarily consume an ORF during the recovery phase of their illness and that consumption of the ORF may foster a more rapid return of voluntary appetite as well as improved caloric intake. Additional studies are warranted to further assess additional effects of this ORF during recovery from CPV.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors.forename: Reut
authors.initials: R
authors.lastname: Tenne
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA. Electronic address: lauren.sullivan@colostate.edu.
authors.forename: Lauren A
authors.initials: LA
authors.lastname: Sullivan
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors.forename: Elena T
authors.initials: ET
authors.lastname: Contreras
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors.forename: Francisco
authors.initials: F
authors.lastname: Olea-Popelka
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Twedt
authors.affiliation: Dumb Friends League in Denver, Colorado. 2080 Quebec St, Denver, CO 80231.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Fankhauser
authors.affiliation: Dumb Friends League in Denver, Colorado. 2080 Quebec St, Denver, CO 80231.
authors.forename: Logan
authors.initials: L
authors.lastname: Mastrianna
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Lappin
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004751:Enteritis / Q000188:drug therapy / Q000662:veterinary*; D005247:Feeding Behavior; D005260:Female; D005440:Fluid Therapy / Q000662:veterinary*; D008297:Male; D010322:Parvoviridae Infections / Q000188:drug therapy / Q000662:veterinary*; D017993:Parvovirus, Canine; D015532:Rehydration Solutions / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D015532:Rehydration Solutions
keywords: diet; enteral nutrition; oral recuperation fluid; parvovirus