title: Erythrodermic Psoriasis Treated with Apremilast.
abstract: Erythroderma is a rare potentially deadly exfoliative dermatitis characterized by diffuse cutaneous erythema which may be associated with multi-organ dysfunction. Therefore, it is imperative to recognize and treat it promptly. Erythrodermic psoriasis is the most common form of erythroderma. Management of this condition is largely based on aggressive supportive care and the use of anti-inflammatory immunosuppressive and biologic agents. We describe a case of psoriatic erythroderma which was triggered by withdrawal from systemic steroids and successfully treated with apremilast and cyclosporine. Apremilast induced atrial fibrillation limited its continued use after the initial response period.
authors.affiliation: Department of Medicine, Loma Linda University School of Medicine.
authors.forename: John
authors.initials: J
authors.lastname: Arcilla
authors.affiliation: Department of Medicine, Loma Linda University School of Medicine.
authors.forename: Daniel
authors.initials: D
authors.lastname: Joe
authors.affiliation: Department of Medicine, Loma Linda University School of Medicine.
authors.forename: Johnathan
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Medicine, Loma Linda University School of Medicine.
authors.forename: Yohanan
authors.initials: Y
authors.lastname: Kim
authors.affiliation: Department of Medicine, Loma Linda University School of Medicine.
authors.forename: VuAnh N
authors.initials: VN
authors.lastname: Truong
authors.affiliation: Department of Medicine, Loma Linda University School of Medicine; Department of Medicine, VA Loma Linda Healthcare System, Loma Linda, CA, USA.
authors.forename: Navin
authors.initials: N
authors.lastname: Jaipaul
keywords: Apremilast; Erythroderma; Erythrodermic psoriasis; Psoriasis