title: CT Angiographic Evaluation of Pattern and Distribution of Stenosis and its Association with Risk Factors Among Indian Ischemic Stroke Patients.
abstract: BACKGROUND
  Stroke is the major cause of disability and third major cause of death. Ischemia causes about 80% of stroke cases; stenosis and occlusion are the predominant cause of stroke. Our purpose for this study was to evaluate the pattern and distribution of stenosis and its association with risk factors in Indian ischemic stroke patients and in other countries, for comparison.
  
  
  METHODS
  We evaluated 60 patients after ischemic stroke with CT angiography. The degree of stenosis was measured by the North American Symptomatic Carotid Endarterectomy Trial (NASCET). The results were analyzed by descriptive statistics and chi-square test.
  
  
  RESULTS
  Out of 60 cases, 32 cases were positive for significant stenosis and a total number of stenotic segments was 45. Out of 45 stenotic segments, 29 were single stenotic segments (16 intracranial and 13 extracranial) and 16 were multiple stenotic segments (8 intracranial and 8 extracranial). In the total number of stenotic segments (single and multiple), there were 24 (53.33%) intracranial and 21 (46.67%) extracranial. The most commonly involved intracranial stenosis segment was MCA, present in 10 (41.6%) out of 24 intracranial segments. Most commonly involved extracranial stenosis segment was ICA, present in 14 (66.6%) out of 21 extracranial segments. Diabetes is found to be the most common risk factor of intracranial stenosis while hypertension and hypercholesterolemia are the major risk factors of extracranial stenosis.
  
  
  CONCLUSIONS
  In the Indian population, intracranial stenosis is more common than extracranial one, anterior circulation stenosis is more common than posterior circulation stenosis; single stenosis is more common than multiple stenosis.
authors.affiliation: Department of Radiology, Mahatma Gandhi Medical College, Jaipur, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Shrivastava
authors.affiliation: Department of Neurology, Sawai ManSingh Medical College and Hospital, Jaipur, India.
authors.forename: Trilochan
authors.initials: T
authors.lastname: Srivastava
authors.affiliation: Department of Public Health Dentistry, Mahatma Gandhi Medical College, Jaipur, India.
authors.forename: Richa
authors.initials: R
authors.lastname: Saxena
keywords: Carotid Stenosis; Cerebral Angiography; India; Stroke