title: Photocatalytic Dehydrogenative Cross-Coupling of Alkenes with Alcohols or Azoles without External Oxidant.
abstract: Direct cross-coupling between alkenes/R-H or alkenes/RXH is a dream reaction, especially without external oxidants. Inputting energy by photocatalysis and employing a cobalt catalyst as a two-electron acceptor, a direct C-H/X-H cross-coupling with H2evolution has been achieved for C-O and C-N bond formation. A new radical alkenylation using alkene as the redox compound is presented. A wide range of aliphatic alcohols-even long chain alcohols-are tolerated well in this system, providing a new route to multi-substituted enol ether derivatives using simple alkenes. Additionally, this protocol can also be used for N-vinylazole synthesis. Mechanistic insights reveal that the cobalt catalyst oxidizes the photocatalyst to revive the photocatalytic cycle.
authors.affiliation: College of Chemistry and Molecular Sciences, The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, 430072, Hubei, P.R. China.
authors.forename: Hong
authors.initials: H
authors.lastname: Yi
authors.affiliation: College of Chemistry and Molecular Sciences, The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, 430072, Hubei, P.R. China.
authors.forename: Linbin
authors.initials: L
authors.lastname: Niu
authors.affiliation: College of Chemistry and Molecular Sciences, The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, 430072, Hubei, P.R. China.
authors.forename: Chunlan
authors.initials: C
authors.lastname: Song
authors.affiliation: College of Chemistry and Molecular Sciences, The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, 430072, Hubei, P.R. China.
authors.forename: Yiying
authors.initials: Y
authors.lastname: Li
authors.affiliation: College of Chemistry and Molecular Sciences, The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, 430072, Hubei, P.R. China.
authors.forename: Bowen
authors.initials: B
authors.lastname: Dou
authors.affiliation: College of Chemistry and Molecular Sciences, The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, 430072, Hubei, P.R. China.
authors.forename: Atul K
authors.initials: AK
authors.lastname: Singh
authors.affiliation: College of Chemistry and Molecular Sciences, The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, 430072, Hubei, P.R. China.|State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, P.R. China.
authors.forename: Aiwen
authors.identifier: 0000-0001-8417-3061
authors.initials: A
authors.lastname: Lei
keywords: C−N bond formation; C−O bond formation; oxidant-free; photocatalysis; radical alkenylation