title: In VivoDetection of the Effect of Electroacupuncture on "Zusanli" Acupoint in Rats with Adjuvant-Induced Arthritis through Optical Coherence Tomography.
abstract: This study aimed to investigate the effect of electroacupuncture (EA) treatment through optical coherence tomography (OCT)in vivoon rats with adjuvant-induced arthritis. OCT images were obtained from the ankle of the right hind paws of the rats in control, model, and EA groups before modelling and 1 day, 8 days, 15 days, 22 days, and 29 days after modelling. Results demonstrated that the OCT signal of the ankle of the right hind paws of the rats was indistinct compared to 1 day after modelling and before modelling in the EA group. In the EA group, the light averaged attenuation coefficients of the ankle tissues decreased as treatment duration was prolonged after EA was administered (3.43, 2.96, 2.61, 2.42, and 2.29 mm-1, resp.). There was a significant difference in attenuation coefficient decrease between the 29th d and the 1st d for EA group compared with control group (P< 0.01). This condition indicated that the light absorption of the ankle of the treated rats in the EA group decreased. Therefore, OCT can be used to monitor the effect of treatment on rats with arthritisin vivo.
authors.affiliation: SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
authors.forename: Huiqing
authors.identifier: 0000-0003-1433-5146
authors.initials: H
authors.lastname: Zhong
authors.affiliation: Infinitus (China) Company Ltd., Guangzhou 510665, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Yang
authors.affiliation: Infinitus (China) Company Ltd., Guangzhou 510665, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
authors.forename: Zhouyi
authors.identifier: 0000-0003-4518-4862
authors.initials: Z
authors.lastname: Guo
authors.affiliation: SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
authors.forename: Xiuli
authors.initials: X
authors.lastname: Wu
authors.affiliation: SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
authors.forename: Chengkang
authors.initials: C
authors.lastname: Su
authors.affiliation: Infinitus (China) Company Ltd., Guangzhou 510665, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Long
authors.affiliation: Infinitus (China) Company Ltd., Guangzhou 510665, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Lin
authors.affiliation: SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou 510631, China.
authors.forename: Xuemei
authors.identifier: 0000-0001-6220-4293
authors.initials: X
authors.lastname: Jiang
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D001169:Arthritis, Experimental / Q000628:therapy*; D004195:Disease Models, Animal; D015671:Electroacupuncture / Q000379:methods*; D005260:Female; D008297:Male; D017208:Rats, Wistar; D041623:Tomography, Optical Coherence / Q000379:methods*