title: Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations.
abstract: Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.
authors.affiliation: Service of Hematology and Hematopoietic Cell Transplantation, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Brazil.
authors.forename: Fernando Barroso
authors.initials: FB
authors.lastname: Duarte
authors.affiliation: Service of Apheresis, Centro Regional de Hemoterapia, HCFMRP-USP, Brazil.
authors.forename: Benedito de Pina Almeida
authors.initials: BP
authors.lastname: Prado
authors.affiliation: Department of Clinical Oncology and BMT Unit, AC Camargo Cancer Center, Brazil.
authors.forename: Garles Miller Matias
authors.initials: GM
authors.lastname: Vieira
authors.affiliation: Department of Bone Marrow Transplantation and Cell Therapy Program, Department of Medicine and UAB-CCC, Birmingham, AL, USA.
authors.forename: Luciano J
authors.initials: LJ
authors.lastname: Costa
mesh_terms: D018952:Antigens, CD34 / Q000097:blood; D001596:Benzylamines; D002452:Cell Count; D000080027:Cyclams; D016179:Granulocyte Colony-Stimulating Factor; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006571:Heterocyclic Compounds; D006801:Humans; D012307:Risk Factors; D014182:Transplantation, Autologous / Q000379:methods
chemical_list: D018952:Antigens, CD34; D001596:Benzylamines; D000080027:Cyclams; D006571:Heterocyclic Compounds; D016179:Granulocyte Colony-Stimulating Factor; C088327:plerixafor