title: A Robust and Broadly Applicable Cobalt-Catalyzed Cross-Coupling of Functionalized Bench-Stable Organozinc Pivalates with Unsaturated Halides.
abstract: We report a robust and broadly applicable CoCl2-catalyzed cross-coupling between functionalized aryl and heteroaryl zinc pivalates and various electron-poor aryl and heteroaryl halides (X=Cl, Br, I). Couplings with (E)- or (Z)-bromo- or iodo-alkenes proceed with retention of configuration. Also, alkynyl bromides react with arylzinc pivalates providing arylated alkynes.
authors.affiliation: Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, Haus F, 81377, Munich, Germany.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Hammann
authors.affiliation: Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, Haus F, 81377, Munich, Germany.
authors.forename: Ferdinand H
authors.initials: FH
authors.lastname: Lutter
authors.affiliation: Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, Haus F, 81377, Munich, Germany.
authors.forename: Diana
authors.initials: D
authors.lastname: Haas
authors.affiliation: Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, Haus F, 81377, Munich, Germany.
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel
keywords: N-heterocycles; cobalt; cross-coupling; zinc; zinc pivalate