title: Complete atrioventricular septal defect in the era of prenatal diagnosis.
abstract: Complete atrioventricular septal defect (CAVSD) is a fetal cardiac malformation (5% of all cardiac malformations) that can be detected prenatally with a reserved prognosis. The diagnosis can be suspected early at the end of the first trimester using the transabdominal or transvaginal ultrasound approach. Generally, the diagnostic can be established during the mid-trimester scan at 19-24 weeks of gestation. The percentage of antenatal diagnostic of CAVSD is between 57-92%. This review aims to analyze the anatomical principles and the ultrasound techniques that can improve the prenatal diagnosis of CAVSD. We have also analyzed the structural and genetic anomalies frequently associated with CAVSD.
authors.affiliation: 1st Obstetrics and Gynecology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Daniel
authors.initials: D
authors.lastname: Mureşan
authors.affiliation: Department of Obstetrics and Gynecology I, University of Medicine and Pharmacy of Targu Mures, Romania. marginean.claudiu@gmail.com.
authors.forename: Claudiu
authors.initials: C
authors.lastname: Mărginean
authors.affiliation: Neonatology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Zaharie
authors.affiliation: 1st Obstetrics and Gynecology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Florin
authors.initials: F
authors.lastname: Stamatian
authors.affiliation: 1st Obstetrics and Gynecology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Ioana Cristina
authors.initials: IC
authors.lastname: Rotar
mesh_terms: D015150:Echocardiography, Doppler / Q000379:methods*; D006343:Heart Septal Defects / Q000000981:diagnostic imaging* / Q000196:embryology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D056888:Patient Positioning / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods*