title: The Rate Of Complications Associated With Concomitant Use Of Dabigatran With Cryoballoon Ablation For Atrial Fibrillation.
abstract: BACKGROUND
  Catheter ablation is an evolving therapeutic strategy for the management of atrial fibrillation (AF). It is associated with a risk of thromboembolic events. The peri-procedural anticoagulation management with warfarin has been successful in mitigating this risk. However, introduction of novel oral anticoagulants like dabigatran offers more flexibility in anticoagulation approaches. Previous studies had evaluated the safety and efficacy of dabigatran in the radiofrequency ablation, but data related to cryoballoon ablation is lacking.
  
  
  RESULTS
  We performed a retrospective observational study involving patients who underwent cryoballoon ablation for drug-refractory, symptomatic AF while on dabigatran in periprocedural period. Thromboembolic, hemorrhagic or other complications occurring within the first 30 days after the ablation procedure were analyzed. Our study population comprised of 50 patients with mean age of 58.96 ± 3.54 years with 76% (n=38) being male. We found 3 (6%) minor complications in peri-procedural period including 2 groin hematomas and 1 trace asymptomatic pericardial effusion. There were no major intraprocedural or post procedural hemorrhagic or thromboembolic events. None of patients with the minor complications required significant additional workup or extended hospital stay. All the patients were able to continue dabigatran for 30 days without any additional side effects or complications.
  
  
  CONCLUSIONS
  Dabigatran is a safe and efficacious agent in patients undergoing cryoballoon AF ablation.
authors.affiliation: Department of Electrophysiology, Staten Island University Hospital, NY.
authors.forename: Valay
authors.initials: V
authors.lastname: Parikh
authors.affiliation: Department of Electrophysiology, Staten Island University Hospital, NY.
authors.forename: Vratika
authors.initials: V
authors.lastname: Agarwal
authors.affiliation: Department of Electrophysiology, Staten Island University Hospital, NY.
authors.forename: Jharendra
authors.initials: J
authors.lastname: Rijal
authors.affiliation: Department of Electrophysiology, Staten Island University Hospital, NY.
authors.forename: Vinod
authors.initials: V
authors.lastname: Chainani
authors.affiliation: Department of Electrophysiology, Staten Island University Hospital, NY.
authors.forename: Soad
authors.initials: S
authors.lastname: Bekheit
authors.affiliation: Department of Electrophysiology, Staten Island University Hospital, NY.
authors.forename: Marcin
authors.initials: M
authors.lastname: Kowalski
keywords: Atrial Fibrillation; Cryoballoon Ablation; Dabigatran