title: Stereoselective Analysis and Dissipation of Propiconazole in Wheat, Grapes, and Soil by Supercritical Fluid Chromatography-Tandem Mass Spectrometry.
abstract: An efficient and sensitive chiral analytical method was established for the determination of propiconazole stereoisomers by supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS). Stereoisomeric separation was performed on a Chiralpak AD-3 column with CO2/ethanol (93:7) as the mobile phase. The four propiconazole stereoisomers were well separated in 4.7 min with resolutions above 2.0. The specificity, linearity, matrix effects, accuracy, precision, and stability of the developed method were evaluated. The stereoselective dissipation of propiconazole in wheat straw, grape, and soil samples was investigated according to the proposed method. The results indicated that significant stereoselective degradation occurred in wheat straw and grapes, with preferential degradation of (-)-propiconazole A and (+)-propiconazole B in wheat straw and the opposite case in grapes. No enantioselectivity was observed in soil, although diastereoisomer A degraded more rapidly than diastereoisomer B. These results could contribute to a more accurate assessment of the environmental risk and food safety of propiconazole.
authors.affiliation: Tianjin Agricultural University , Tianjin, China.
authors.forename: Youpu
authors.identifier: http://orcid.org/0000-0002-0171-0165
authors.initials: Y
authors.lastname: Cheng
authors.affiliation: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences , Beijing, China.
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences , Beijing, China.
authors.forename: Fengshou
authors.initials: F
authors.lastname: Dong
authors.affiliation: Institute of Quality Standard and Testing Technology for Agro-products , Tianjin Academy of Agricultural Sciences , Tianjin, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: Tianjin Agricultural University , Tianjin, China.
authors.forename: Yaofang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Tianjin Agricultural University , Tianjin, China.
authors.forename: Shuhong
authors.initials: S
authors.lastname: Sun
authors.affiliation: Tianjin Agricultural University , Tianjin, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Li
authors.affiliation: Tianjin Agricultural University , Tianjin, China.
authors.forename: Xinyi
authors.initials: X
authors.lastname: Cui
authors.affiliation: Tianjin Agricultural University , Tianjin, China.
authors.forename: Yuanhong
authors.initials: Y
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences , Beijing, China.
authors.forename: Xinglu
authors.initials: X
authors.lastname: Pan
authors.affiliation: Tianjin Agricultural University , Tianjin, China.
authors.forename: Weilong
authors.initials: W
authors.lastname: Zhang
mesh_terms: D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D005506:Food Contamination; D005659:Fungicides, Industrial / Q000737:chemistry*; D012989:Soil Pollutants / Q000737:chemistry*; D013237:Stereoisomerism; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014230:Triazoles / Q000737:chemistry*; D014908:Triticum / Q000737:chemistry*; D027843:Vitis / Q000737:chemistry*
chemical_list: D005659:Fungicides, Industrial; D012989:Soil Pollutants; D014230:Triazoles; C045950:propiconazole
keywords: SFC-MS/MS; grapes; propiconazole; stereoselective analysis; wheat