title: Confirmation and next-generation sequencing of allele HLA-B*35:279 found in a family of a leukaemia patient with Western Asia origin.
abstract: The confirmation of novel allele HLA-B*35:279 in a family of a leukaemia patient with Western Asia origin is reported. Moreover, next-generation sequencing (NGS) resulted in whole-gene sequence data and revealed the inheritance of HLA-B*35:279 on the paternal haplotype.
authors.affiliation: Department of Internal Medicine II, Oncology, Haematology, Immunology, Rheumatology and Pulmonology, University of Tübingen, Tübingen, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Grünebach
authors.affiliation: Department of Internal Medicine II, Oncology, Haematology, Immunology, Rheumatology and Pulmonology, University of Tübingen, Tübingen, Germany.
authors.forename: A-L
authors.initials: AL
authors.lastname: Huster
authors.affiliation: Department of Internal Medicine II, Oncology, Haematology, Immunology, Rheumatology and Pulmonology, University of Tübingen, Tübingen, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Vogel
authors.affiliation: Department of Internal Medicine II, Oncology, Haematology, Immunology, Rheumatology and Pulmonology, University of Tübingen, Tübingen, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Klein
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution; D044466:Asian People; D005091:Exons; D015870:Gene Expression; D015797:HLA-B35 Antigen / Q000235:genetics* / Q000276:immunology; D018380:Hematopoietic Stem Cell Transplantation; D059014:High-Throughput Nucleotide Sequencing; D006650:Histocompatibility Testing; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D017354:Point Mutation; D066027:Transplant Recipients
chemical_list: D015797:HLA-B35 Antigen