title: Oral Biofluid Biomarker Research: Current Status and Emerging Frontiers.
abstract: Salivary diagnostics is a rapidly advancing field that offers clinicians and patients the potential of rapid, noninvasive diagnostics with excellent accuracy. In order for the complete realization of the potential of saliva, however, extensive profiling of constituents must be conducted and diagnostic biomarkers must be thoroughly validated. This article briefly overviews the process of conducting a study of salivary biomarkers in a patient cohort and highlights the studies that have been conducted on different classes of molecules in the saliva. Emerging frontiers in salivary diagnostics research that may significantly advance the field will also be highlighted.
authors.affiliation: School of Dentistry, University of California at Los Angeles, Los Angeles, CA 90095, USA. wang25austin@ucla.edu.
authors.forename: Austin
authors.initials: A
authors.lastname: Wang
authors.affiliation: School of Dentistry, University of California at Los Angeles, Los Angeles, CA 90095, USA. chriswang9409@gmail.com.
authors.forename: Chris P
authors.initials: CP
authors.lastname: Wang
authors.affiliation: School of Dentistry, University of California at Los Angeles, Los Angeles, CA 90095, USA. emtu@ucla.edu.
authors.forename: Michael
authors.initials: M
authors.lastname: Tu
authors.affiliation: School of Dentistry, University of California at Los Angeles, Los Angeles, CA 90095, USA. dtww@ucla.edu.
authors.forename: David T W
authors.initials: DT
authors.lastname: Wong
keywords: biomarkers; noninvasive; salivary diagnostics