title: [Colorectal cancer surgery in the oldest Dutch patients: retrospective analysis of two national databases covering 2011 and 2012].
abstract: Adequate decision-making concerning elderly patients with colorectal cancer requires accurate information regarding the risks of treatment. We analysed the post-operative outcomes and survival following colorectal resections in the oldest old patients (≥ 85 years old).
  
  
  
  Retrospective study.
  
  
  
  We analysed the data from 2011 and 2012 of all patients with colorectal carcinoma, stage I-III, from two national databases, namely the Dutch Surgical Colorectal Audit registry (DSCA) and the Netherlands Cancer Registry (NKR).
  
  
  
  The study included over 1200 elderly patients. The postoperative complication rate was 41%. The frequency of cardiopulmonary complications rose rapidly with age, from 11% in those < 70 years to 38% in those aged > 85 years. The postoperative 30-day mortality rate was 10% for the oldest old patients, whereas it was 14% after three months, 24% after one year and 36% after two years. After correction for expected mortality in the general population, excess mortality for the oldest old was 12% in the first year and 3% in the second year.
  
  
  
  For patients aged ≥ 85 years who undergo surgical resection for colorectal carcinoma, high rates of cardiopulmonary complications and excess mortality in the first year after surgery are observed. We propose that these data could be analysed together with information regarding individual patients' health status, to enable optimisation of future decision-making regarding potential surgical intervention in elderly patients.
authors.affiliation: *Dit onderzoek werd eerder gepubliceerd in Annals of Surgical Oncology (2016;23:1875-82) met als titel 'Colorectal cancer resections in the oldest old between 2011 and 2012 in the Netherlands'. Afgedrukt met toestemming.
authors.forename: N M
authors.initials: NM
authors.lastname: Verweij
authors.forename: A H W
authors.initials: AH
authors.lastname: Schiphorst
authors.forename: H A
authors.initials: HA
authors.lastname: Maas
authors.forename: D D E
authors.initials: DD
authors.lastname: Zimmerman
authors.forename: F
authors.initials: F
authors.lastname: van den Bos
authors.forename: A
authors.initials: A
authors.lastname: Pronk
authors.forename: I H M
authors.initials: IH
authors.lastname: Borel Rinkes
authors.forename: M E
authors.initials: ME
authors.lastname: Hamakers
mesh_terms: D000367:Age Factors; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000401:mortality / Q000601:surgery*; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008297:Male; D009426:Netherlands; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome