title: Diet, Lifestyles, Family History, and Prostate Cancer Incidence in an East Algerian Patient Group.
abstract: Prostate cancer (PC) is the fourth most common cancer in men and the sixth leading cause of death in Algeria. To examine the relationship between lifestyle factors, including diet, and family history and PC risk, a case-control study was performed in an eastern Algerian population, comprising 90 patients with histologically confirmed PC and 190 controls. Data collection was carried out through a structured questionnaire and statistical analysis was performed to evaluate the different variables. The data showed that consumption of lamb and beef meat and high intake of animal fat and dairy products increased PC risk. Seven to thirteen vegetables servings per week and fourteen or more servings decreased PC risk by 62% and 96%, respectively. Seven to fourteen fruit servings per week decrease PC risk by 98%. Green tea consumption reduced the risk of PC but the results were statistically borderline. Increased risk was observed for individuals with family history of PC in first and in second degree. A positive strong association was also found for alcohol and smoking intake and a dose-response relationship existed for quantity and history of smoking. This study suggests that dietary habits, lifestyle factors, and family history have influence on the development of PC in Algerian population.
authors.affiliation: Unité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri, Constantine, 25000 Constantine, Algeria; Laboratoire de Physiologie Animale, Département de Biologie Animale, Faculté des Sciences de la Nature et de la Vie, Université des Frères Mentouri, Constantine, 25000 Constantine, Algeria.
authors.forename: Somia
authors.initials: S
authors.lastname: Lassed
authors.affiliation: Center for Neuroscience and Cellular Biology (CNC), University of Coimbra, UC Biotech Building, Biocant Park, 3060-197 Cantanhede, Portugal.
authors.forename: Cláudia M
authors.initials: CM
authors.lastname: Deus
authors.affiliation: Department of Informatics Engineering, Center for Informatics and Systems of University of Coimbra (CISUC), Polo II-Pinhal de Marrocos, 3030 Coimbra, Portugal.
authors.forename: Nuno
authors.initials: N
authors.lastname: Lourenço
authors.affiliation: Clinic of Urology-Nephrology and Kidney Transplant Daksi, 25000 Constantine, Algeria.
authors.forename: Abderrezak
authors.initials: A
authors.lastname: Dahdouh
authors.affiliation: Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
authors.forename: Albert A
authors.identifier: 0000-0002-9427-5739
authors.initials: AA
authors.lastname: Rizvanov
authors.affiliation: Center for Neuroscience and Cellular Biology (CNC), University of Coimbra, UC Biotech Building, Biocant Park, 3060-197 Cantanhede, Portugal.
authors.forename: Paulo J
authors.identifier: 0000-0002-5201-9948
authors.initials: PJ
authors.lastname: Oliveira
authors.affiliation: Unité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri, Constantine, 25000 Constantine, Algeria.
authors.forename: Djamila
authors.identifier: 0000-0002-4312-7701
authors.initials: D
authors.lastname: Zama
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000453:epidemiology*; D000462:Algeria / Q000453:epidemiology; D016022:Case-Control Studies; D004032:Diet / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008019:Life Style; D008297:Male; D008487:Medical History Taking / Q000706:statistics & numerical data*; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology*