title: Visualization of the improvement of myocardial perfusion after coronary intervention using motorized fractional flow reserve pullback curve.
abstract: This study aimed to evaluate the feasibility and utility of using motorized pullback of the pressure guidewire to provide a graphic assessment and prediction of the benefits of coronary intervention. Fractional flow reserve (FFR) measurements were performed with motorized pullback imaging in 20 patients who underwent successful percutaneous coronary intervention (PCI) of the left anterior descending artery. Physiological lesion length (PLL) was calculated using frame counts to determine stent length. FFR area was calculated by integrating the FFR values recorded during pullback tracing (FFRarea). The percentage increase in FFR area (%FFRarea) was defined as the ratio of the difference between the pre- and post-intervention FFRarea to the total frame count. The average FFR values were enhanced following PCI, from 0.64 to 0.82, and the median value of the difference between pre- and post-interventional FFR values (D-FFR) and %FFRarea were 0.13 and 10.6%, respectively. The %FFRarea demonstrated a significant positive correlation with D-FFR (R2, 0.61; p < 0.01). PLL tended to be longer and the %FFRarea was smaller in lesions with a gradual pressure-drop pattern than those with an abrupt pressure-drop pattern (35.37 vs. 20.40 mm, p = 0.07; 5.78 vs. 16.21%, p < 0.05, respectively). Motorized pullback tracing was able to identify the extent and location of stenosis and help in appropriate stent implantation, in addition to visualizing and quantifying the improvement in FFR following PCI.
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan. kiakiko@mx4.canvas.ne.jp.
authors.forename: Akiko
authors.initials: A
authors.lastname: Matsuo
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Shimoo
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Takamatsu
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Yumika
authors.initials: Y
authors.lastname: Tsuji
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kyodo
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Kayoko
authors.initials: K
authors.lastname: Mera
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Koide
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Isodono
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Tsubakimoto
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Sakatani
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Inoue
authors.affiliation: Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, 355-5 Haruobi-cho, Marutamachi Kamannza-dori, Kamigyo-ku, Kyoto, 602-8026, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fujita
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization / Q000295:instrumentation / Q000379:methods; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy*; D003331:Coronary Vessels / Q000503:physiopathology; D005260:Female; D053805:Fractional Flow Reserve, Myocardial / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging; D062645:Percutaneous Coronary Intervention
keywords: Coronary intervention; Fractional flow reserve; Motorized pullback curve