title: Unusual psychotic presentation after discontinuation of treatment in a patient with Wilson's disease: a case report.
abstract: Psychiatric manifestations are common in patients with Wilson's Disease(WD), and they are usually correlated with neurological symptoms. However, psychotic presentation without neurological symptoms has rarely been reported. We present a case of WD involving a 34-year-old gentleman who was diagnosed at the age of 22, but due to lack of medication for approximately 5 months was admitted in a psychiatric ward with delusional thoughts of grandeur and persecution, echopraxia and echolalia. No neurological impairment, ophthalmic manifestations or liver abnormalities were identified. Through this report, we aim to discuss the pathophysiology and the treatment of psychosis in WD, and its association with neurological, liver and ophthalmic manifestations.
authors.affiliation: 1. South Staffordshire and Shropshire NHS Foundation Trust, Corporation Str., Stafford, ST16 3AG, West Midlands, United Kingdom.|2. Burton Hospitals NHS Foundation Trust, Belvedere Road, Burton upon Trent, Staffordshire, DE13 0RB, West Midlands, United Kingdom.
authors.forename: Andreas S
authors.initials: AS
authors.lastname: Lappas
authors.affiliation: 1. South Staffordshire and Shropshire NHS Foundation Trust, Corporation Str., Stafford, ST16 3AG, West Midlands, United Kingdom.
authors.forename: Fiesal
authors.initials: F
authors.lastname: Jan
keywords: Wilson's disease; antipsychotics; paranoia; psychosis