title: Phagocytosis: How Macrophages Tune Their Non-professional Counterparts.
abstract: Foreign particles and apoptotic cells are engulfed by professional phagocytes (e.g. macrophages) and non-professional phagocytes (e.g. epithelial cells). These phagocyte populations exchange information to coordinate and prioritise their activities, but the nature of these messages was unknown. Recently, IGF-1 and microvesicles were identified as means of communication between macrophages and epithelia.
authors.affiliation: Program in Cell Biology, Hospital for Sick Children, 686 Bay Street, Toronto, Ontario, M5G 0A4, Canada.
authors.forename: Spencer A
authors.initials: SA
authors.lastname: Freeman
authors.affiliation: Program in Cell Biology, Hospital for Sick Children, 686 Bay Street, Toronto, Ontario, M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, Ontario, M5S 1A8, Canada; Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, 290 Victoria Street, Toronto, Ontario, M5C 1N8, Canada. Electronic address: sergio.grinstein@sickkids.ca.
authors.forename: Sergio
authors.initials: S
authors.lastname: Grinstein
mesh_terms: D000818:Animals; D002450:Cell Communication; D055252:Cell-Derived Microparticles / Q000502:physiology*; D004847:Epithelial Cells / Q000502:physiology; D007249:Inflammation / Q000378:metabolism; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008264:Macrophages / Q000502:physiology*; D008322:Mammals / Q000276:immunology / Q000502:physiology*; D010587:Phagocytosis / Q000502:physiology*
chemical_list: D007334:Insulin-Like Growth Factor I