title: Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation.
abstract: Impact microindentation is a novel method for measuring the resistance of cortical bone to indentation in patients. Clinical use of a handheld impact microindentation technique is expanding, highlighting the need to standardize the measurement technique. Here, we describe a detailed standard operation procedure to improve the consistency and comparability of the measurements across centers.
authors.affiliation: Department of Internal Medicine, Hospital del Mar-IMIM, Autonomous University of Barcelona and RETICEF, Instituto Carlos III, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Diez-Perez
authors.affiliation: Center for Advanced Orthopedic Studies, Beth Isreal Deaconess Medical Center and Department of Orthopedic Surgery, Harvard Medical School, Boston, MA, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Bouxsein
authors.affiliation: Dept. of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.
authors.forename: E F
authors.initials: EF
authors.lastname: Eriksen
authors.affiliation: Division of Endocrinology and Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
authors.forename: S
authors.initials: S
authors.lastname: Khosla
authors.affiliation: Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Nyman
authors.affiliation: Center for Bone Quality, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Papapoulos
authors.affiliation: Department of Orthopaedic Surgery, Washington University in St Louis, St Louis, MO, USA.
authors.forename: S Y
authors.initials: SY
authors.lastname: Tang
keywords: Bone microindentation; Bone tissue characteristics; Impact microindentation