title: Controlled Dimroth Rearrangement in the Suzuki-Miyaura Cross Coupling of Triazolopyridopyrimidines.
abstract: Polynitrogen heterocycles are often subject to Dimroth rearrangement which consists of ring opening, bond rotation, and ring closure. In this note, we report a synthesis of two new families of triazolopyridopyrimidines. Successful functionalization via a Suzuki-Miyaura coupling was performed with total control of triazole (Dimroth) isomerization based on the judicious choice of reaction conditions.
authors.affiliation: Institut de Chimie Organique et Analytique (ICOA) UMR 7311, University of Orléans, CNRS , BP 6759, Orléans F-45067, France.
authors.forename: Anthony
authors.initials: A
authors.lastname: Champiré
authors.affiliation: Institut de Chimie Organique et Analytique (ICOA) UMR 7311, University of Orléans, CNRS , BP 6759, Orléans F-45067, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Vala
authors.affiliation: Institut de Chimie Organique et Analytique (ICOA) UMR 7311, University of Orléans, CNRS , BP 6759, Orléans F-45067, France.|Faculty of Sciences Semlalia, Cadi Ayyad University , BP 2390, Marrakech 40000, Morocco.
authors.forename: Achraf
authors.initials: A
authors.lastname: Laabid
authors.affiliation: Faculty of Sciences Semlalia, Cadi Ayyad University , BP 2390, Marrakech 40000, Morocco.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Benharref
authors.affiliation: CNRS, University of Bordeaux, ICMCB, UPR 9048 , Pessac F-33600, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Marchivie
authors.affiliation: Institut de Chimie Organique et Analytique (ICOA) UMR 7311, University of Orléans, CNRS , BP 6759, Orléans F-45067, France.
authors.forename: Karen
authors.initials: K
authors.lastname: Plé
authors.affiliation: Institut de Chimie Organique et Analytique (ICOA) UMR 7311, University of Orléans, CNRS , BP 6759, Orléans F-45067, France.
authors.forename: Sylvain
authors.identifier: 0000-0002-2823-0591
authors.initials: S
authors.lastname: Routier