title: [Neurobiological aspects of personality disorders and emotional instability].
abstract: Neurobiological aspects of personality disorders and emotional instability ADHD and mental disorders encompassing emotional instability such as emotionally unstable personality disorder and antisocial personality disorder can potentially be explained by a suboptimal regulation of information processing in the brain. ADHD involves suboptimal function of non-emotional attentional regulatory processes and emotional instability involves suboptimal emotional regulation. A network including prefrontal areas, anterior cingulate cortex, basal ganglia and specific neuromodulatory systems such as the dopamine system are dysfunctional in both ADHD and emotional instability. One might suggest that a dimensional view better describes these mental states than categorical diagnoses.
authors.affiliation: Karolinska Institutet - Institutionen för klinisk neurovetenskap Stockholm, Sweden Karolinska Institutet - Institutionen för klinisk neurovetenskap Stockholm, Sweden.
authors.forename: Predrag
authors.initials: P
authors.lastname: Petrovic
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D004644:Emotions / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010554:Personality Disorders / Q000503:physiopathology*; D012737:Sex Factors