title: Therapeutic evolution of benzimidazole derivatives in the last quinquennial period.
abstract: Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained considerable attention in the field of contemporary medicinal chemistry. The moiety is of substantial importance because of its wide array of pharmacological activities. This nitrogen containing heterocycle is a part of a number of therapeutically used agents. Moreover, a number of patents concerning this moiety in the last few years further highlight its worth. The present review covers the recent work published by scientists across the globe during last five years.
authors.affiliation: Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India.
authors.forename: Wasim
authors.initials: W
authors.lastname: Akhtar
authors.affiliation: Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India.
authors.forename: Mohemmed Faraz
authors.initials: MF
authors.lastname: Khan
authors.affiliation: Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India.
authors.forename: Garima
authors.initials: G
authors.lastname: Verma
authors.affiliation: Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India.
authors.forename: M
authors.initials: M
authors.lastname: Shaquiquzzaman
authors.affiliation: Department of Biosciences, Jamia Millia Islamia, New Delhi 110025, India.
authors.forename: M A
authors.initials: MA
authors.lastname: Rizvi
authors.affiliation: Department of Biosciences, Jamia Millia Islamia, New Delhi 110025, India.
authors.forename: Syed Hassan
authors.initials: SH
authors.lastname: Mehdi
authors.affiliation: Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India.
authors.forename: Mymoona
authors.initials: M
authors.lastname: Akhter
authors.affiliation: Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India. Electronic address: drmmalam@gmail.com.
authors.forename: M Mumtaz
authors.initials: MM
authors.lastname: Alam
mesh_terms: D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000627:therapeutic use; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D055808:Drug Discovery; D006571:Heterocyclic Compounds / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D001562:Benzimidazoles; D006571:Heterocyclic Compounds
keywords: Anti-cancer; Anti-inflammatory and analgesic; Antiviral; Benzimidazole; Biological activity; Heterocyclic