title: Transarterial Therapies for Hepatocellular Carcinoma.
abstract: BACKGROUND
  The treatment of hepatocellular carcinoma (HCC) is still a major health issue because of its increasing incidence and because of the complexity of its management. Transarterial embolization (TAE) and transarterial chemoembolization (TACE) are two widely used locoregional therapies in the treatment of HCC, especially for unresectable intermediate and advanced HCCs.
  
  
  CONCLUSIONS
  The modern use of TAE and TACE opens new scenarios for the treatment of unresectable HCC and has yielded interesting results. The present work describes the role of transarterial therapies for HCC and focuses on the different Western and Eastern approaches to the study of response predictors.
  
  
  CONCLUSIONS
  Recent refinements in interventional radiology techniques and in HCC patient selection have facilitated better local control of the disease. The molecular profiling of HCC to predict the response to TACE and TAE will greatly help clinicians identify the optimum therapy.
authors.affiliation: Department of Interventional Radiology, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy.
authors.forename: Ezio
authors.initials: E
authors.lastname: Lanza
authors.affiliation: Department of Hepatobiliary and General Surgery, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Donadon
authors.affiliation: Department of Interventional Radiology, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy.
authors.forename: Dario
authors.initials: D
authors.lastname: Poretti
authors.affiliation: Department of Interventional Radiology, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Pedicini
authors.affiliation: Department of Interventional Radiology, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Tramarin
authors.affiliation: Department of Pathology, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Roncalli
authors.affiliation: Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Hyungjin
authors.initials: H
authors.lastname: Rhee
authors.affiliation: Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Young Nyun
authors.initials: YN
authors.lastname: Park
authors.affiliation: Department of Hepatobiliary and General Surgery, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Torzilli
keywords: Predictors of response after TAE and TACE for HCC; TAE and TACE for HCC