title: Spontaneous coronary artery dissection in a young woman with polycystic ovarian syndrome.
abstract: Polycystic ovarian syndrome (PCOS) affects 4% to 12% of women in reproductive age, representing a clinical condition that could predispose to cardiovascular diseases. We report a case of a 34-year-old woman with PCOS, presenting with chest pain, onset two days before, and ST segment-elevation myocardial infarction. She was not pregnant or in a postpartum state. Subsequent cardiac angiography revealed spontaneous left anterior descending coronary artery dissections, managed by conservative approach. The patient was discharged in medical therapy after 5days. This is the first observation of spontaneous coronary artery dissection occurring in a PCOS patient.
authors.affiliation: Department of Translational Medical Sciences, Federico II University, Naples, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Mirra
authors.affiliation: Department of Translational Medical Sciences, Federico II University, Naples, Italy.
authors.forename: Nertil
authors.initials: N
authors.lastname: Kola
authors.affiliation: Department of Translational Medical Sciences, Federico II University, Naples, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Mattiello
authors.affiliation: Department of Advanced Medical Sciences, Federico II University, Naples, Italy.
authors.forename: Carmine
authors.initials: C
authors.lastname: Morisco
authors.affiliation: Department of Advanced Medical Sciences, Federico II University, Naples, Italy. Electronic address: letspine@unina.it.
authors.forename: Letizia
authors.initials: L
authors.lastname: Spinelli
mesh_terms: D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging* / Q000188:drug therapy; D000241:Adenosine / Q000031:analogs & derivatives / Q000627:therapeutic use; D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D002637:Chest Pain / Q000175:diagnosis / Q000209:etiology; D017023:Coronary Angiography; D003330:Coronary Vessel Anomalies / Q000000981:diagnostic imaging* / Q000188:drug therapy; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D058921:Purinergic P2Y Receptor Antagonists / Q000627:therapeutic use; D000077486:Ticagrelor; D014652:Vascular Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000188:drug therapy
chemical_list: D010975:Platelet Aggregation Inhibitors; D058921:Purinergic P2Y Receptor Antagonists; D000077486:Ticagrelor; D000241:Adenosine; D001241:Aspirin
keywords: Acute coronary syndrome; Polycystic ovarian syndrome; Spontaneous coronary artery dissection