title: Somatic comorbidity among migrants with posttraumatic stress disorder and depression - a prospective cohort study.
abstract: BACKGROUND
  In a cohort of migrants in Denmark, we compared somatic disease incidence among migrants diagnosed with posttraumatic stress disorder (PTSD) and depression with migrants without a diagnosed psychiatric disorder.
  
  
  METHODS
  The study builds on a unique cohort of migrants who obtained residence permit in Denmark from 1993 to 2010 (N = 92,104). The association with somatic disease was explored via register linkage. We used Poisson regression to model incidence rate ratios (IRR) adjusted for age, sex, income and region of origin. The Danish Data Protection Agency granted authorisation for the implementation of the project (No 2012-41-0065).
  
  
  RESULTS
  Our results showed that migrants diagnosed with PTSD and depression had significantly higher rates of somatic diseases compared with migrants without diagnosed psychiatric disorders - especially, infectious disease (IRR, 1.89; 95% CI, 1.45-2.48; p < 0.01), neurological disease (IRR, 2.35; 95% CI, 1.91-2.91; p < 0.01) and pulmonary disease (IRR, 1.69; 95% CI, 1.37-2.00; p < 0.01). We further saw differences in the IRRs according to region of origin.
  
  
  CONCLUSIONS
  Migrants with PTSD and depression had a significantly higher rates of somatic comorbidity compared with migrants without a diagnosed psychiatric disorder. The rates were especially high for infectious, neurological and pulmonary diseases. Our results further suggest difference in the rates of somatic comorbidity according to region of. Preventive and treatment services should pay special attention to improve the overall health of migrants with PTSD and depression.
authors.affiliation: Danish Research Centre for Migration, Ethnicity and Health, Section of Health Services Research, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5A, Copenhagen, Denmark. mettelolk@gmail.com.|Competence Centre for Transcultural Psychiatry, Mental Health Centre Ballerup, Mental Health Services of the Capital Region of Denmark, Maglevaenget 2, 2750, Ballerup, Denmark. mettelolk@gmail.com.
authors.forename: Mette
authors.initials: M
authors.lastname: Lolk
authors.affiliation: Danish Research Centre for Migration, Ethnicity and Health, Section of Health Services Research, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5A, Copenhagen, Denmark.
authors.forename: Stine
authors.initials: S
authors.lastname: Byberg
authors.affiliation: Competence Centre for Transcultural Psychiatry, Mental Health Centre Ballerup, Mental Health Services of the Capital Region of Denmark, Maglevaenget 2, 2750, Ballerup, Denmark.
authors.forename: Jessica
authors.initials: J
authors.lastname: Carlsson
authors.affiliation: Danish Research Centre for Migration, Ethnicity and Health, Section of Health Services Research, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5A, Copenhagen, Denmark.|Department of Immigrant Medicine, Section of Infectious Diseases, Hvidovre Hospital, Kettegård Allé 30, Copenhagen, Denmark.
authors.forename: Marie
authors.initials: M
authors.lastname: Norredam
mesh_terms: D000328:Adult; D015331:Cohort Studies; D015897:Comorbidity; D003718:Denmark / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013313:Stress Disorders, Post-Traumatic / Q000453:epidemiology*; D014171:Transients and Migrants / Q000523:psychology / Q000706:statistics & numerical data*; D055815:Young Adult
keywords: Comorbidity; Depression; Migrant; Post-traumatic stress disorder; Refugee