title: Pharmacogenetic Implementation Lessons From the "Real World".
abstract: The manuscript "Anticoagulation Endpoints With Clinical Implementation of Warfarin Pharmacogenetic Dosing in a Real- World Setting: A Proposal for a New Pharmacogenetic Dosing Approach" describes process outcomes in an institutional program to use pharmacogenetic testing to optimize warfarin dose in a cohort of 257 patients of diverse ancestries. The strengths and weaknesses of the approach and program are discussed, along with the current and potential future status of warfarin as a model for pharmacogenetic testing.
authors.affiliation: Departments of Medicine, Pharmacology, and Biomedical Informatics, Oates Institute for Experimental Therapeutics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Roden
mesh_terms: D000465:Algorithms; D000925:Anticoagulants; D006801:Humans; D010597:Pharmacogenetics; D000071185:Pharmacogenomic Testing; D014859:Warfarin
chemical_list: D000925:Anticoagulants; D014859:Warfarin