title: Association of ABO blood group polymorphism and tuberculosis: A study on Bengalee Hindu caste population, West Bengal, India.
abstract: Tuberculosis (TB) is an infectious disease commonly caused by the bacillus mycobacterium and worldwide estimation demonstrated that more than 8.6 million people are infected by TB. Many of the previous studies reported the association between TB and ABO blood group polymorphism. In this context, the objective of the present study is to understand the association of ABO blood group polymorphism and TB in Bengalee Hindu caste population. The present study consists of 100 clinically diagnosed TB patients and 100 apparently healthy individuals with no previous history of TB from the same population of the same area. The distribution of ABO phenotypes demonstrated significant (p<0.05) excess of AB blood group in TB patients and significant (p<0.05) decrease of O blood group in controls. Logistic regression analysis revealed that individuals with non O blood group have 1.97 times (95% CI 1.04-3.75) greater chance of developing TB than individuals with O blood group.
authors.affiliation: Research Student, Department of Anthropology, University College of Science, Technology & Agriculture, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India.
authors.forename: S
authors.initials: S
authors.lastname: Ganguly
authors.affiliation: UGC (NET), Junior Research Fellow, University College of Science, Technology & Agriculture, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India.
authors.forename: P
authors.initials: P
authors.lastname: Sarkar
authors.affiliation: Assistant Professor, Department of Anthropology, University College of Science, Technology & Agriculture, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India.
authors.forename: D
authors.initials: D
authors.lastname: Chatterjee
authors.affiliation: Professor, Department of Anthropology, University College of Science, Technology & Agriculture, University of Calcutta, 35, Ballygunge Circular Road, Kolkata 700019, India. Electronic address: arup.cu@gmail.com.
authors.forename: A R
authors.initials: AR
authors.lastname: Bandyopadhyay
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics*; D016022:Case-Control Studies; D006801:Humans; D007194:India / Q000453:epidemiology; D010641:Phenotype; D011110:Polymorphism, Genetic; D012923:Social Class; D014376:Tuberculosis / Q000097:blood / Q000453:epidemiology / Q000235:genetics*
chemical_list: D000017:ABO Blood-Group System
keywords: ABO blood group polymorphism; Allele frequency; Bengalee Hindu caste; Logistic regression; Tuberculosis