title: Nebulized epinephrine for young children with bronchiolitis.
abstract: OBJECTIVE
  Every winter I see infants with flulike symptoms and wheezing. I frequently diagnose them with bronchiolitis based on their presenting symptoms. Would it be prudent to send those infants to the nearest emergency department for treatment with nebulized epinephrine?
  
  
  CONCLUSIONS
  Nebulized epinephrine should not be routinely used in infants with bronchiolitis. It is an option to consider in those with severe symptoms. If it is given and there are no signs of improvement, further doses are discouraged. Ongoing studies of epinephrine combined with other agents (eg, hypertonic saline, oral dexamethasone) are needed to confirm their benefit.
authors.forename: Teeranai
authors.initials: T
authors.lastname: Sakulchit
authors.forename: Ran D
authors.initials: RD
authors.lastname: Goldman
mesh_terms: D001988:Bronchiolitis / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D003907:Dexamethasone / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D004636:Emergency Service, Hospital; D004837:Epinephrine / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007902:Length of Stay; D009330:Nebulizers and Vaporizers; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D001993:Bronchodilator Agents; D012462:Saline Solution, Hypertonic; D003907:Dexamethasone; D004837:Epinephrine