title: [Association between resting heart rate and metabolic syndrome: a cohort study].
abstract: Objective:To investigate the association between resting heart rate (RHR) and subsequent metabolic syndrome (MS).Methods:Under a cluster design, participants age ≥18 years old were selected from a rural area of Henan province in China. Interview through questionnaire, physical examination, fasting blood glucose, and lipid profile measurements were done from July to August of 2007 and July to August of 2008. Same methods were implemented in the follow-up examination, during July to August of 2013 and July to October of 2014.Results:During the 6-year follow-up period, cumulative incidence rates of MS for overall, male, and female participants appeared as 21.89%(1 933/8 829), 16.78%(664/3 957) and 26.05%(1 269/4 872), respectively. After controlling for potential confounders and compared with the groups of RHR<60 bpm, 60-69, 70-79, 80-89 and ≥90 bpm, theORs(95%CIs) of MS for overall, male, and female participants became 1.24(0.95-1.60), 1.42(1.10-1.84), 1.63(1.24-2.15) and 1.62(1.16-2.27); 1.12(0.81-1.55), 1.23(0.88-1.71), 1.42 (0.97-2.07) and 1.84(1.09-3.11); 1.46(0.93-2.29), 1.70(1.09-2.65), 1.99(1.25-3.16) and 1.78(1.06-2.98); respectively.Conclusions:The risk on MS appeared higher in females than in males while the risk for MS increased with the elevation of RHR. Intensive intervention programs that targeted adult participants with elevated RHR, especially in females, should be formulated and implemented.
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: C Y
authors.initials: CY
authors.lastname: Han
authors.affiliation: Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen 518060, China.
authors.forename: X P
authors.initials: XP
authors.lastname: Luo
authors.affiliation: Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen 518060, China.
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: Y C
authors.initials: YC
authors.lastname: Ren
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: B Y
authors.initials: BY
authors.lastname: Wang
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: H Y
authors.initials: HY
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: X Y
authors.initials: XY
authors.lastname: Yang
authors.affiliation: Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen 518060, China.
authors.forename: J M
authors.initials: JM
authors.lastname: Zhou
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: X J
authors.initials: XJ
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: D D
authors.initials: DD
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: L L
authors.initials: LL
authors.lastname: Li
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: C J
authors.initials: CJ
authors.lastname: Wang
authors.affiliation: Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou 450003, China.
authors.forename: L
authors.initials: L
authors.lastname: Yin
authors.affiliation: Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou 450003, China.
authors.forename: C
authors.initials: C
authors.lastname: Pang
authors.affiliation: Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou 450003, China.
authors.forename: T P
authors.initials: TP
authors.lastname: Feng
authors.affiliation: Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou 450003, China.
authors.forename: J Z
authors.initials: JZ
authors.lastname: Zhao
authors.affiliation: Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: D S
authors.initials: DS
authors.lastname: Hu
mesh_terms: D015331:Cohort Studies; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome; D012306:Risk