title: Validation of Persian version of WHOQOL-HIV BREF questionnaire in Islamic Republic of Iran.
abstract: The aim of this cross-sectional study was to validate the first Persian version of the WHOQOL-HIV BREF questionnaire. The study sample comprised 61 patients regularly attending the outpatient infectious disease clinic consultation centre for patients with behavioural disorders in 2013-2014. The internal consistency, content related validity and reliability of WHOQOL-HIV BREF were evaluated. Content validity was quantified using the content validity ratio (CVR) according the to Lawshe formula. CVR > 0.51 and mean judgment > 2 were significant at P = 0.05. The Cronbach alpha score was > 0.7 for each domain and = 0.87 for the whole scale, indicating good reliability. Item-to-total correlation coefficient between each item and its respective domain was 0.39-0.87. The correlation between each domain and overall QOL was excellent. This study demonstrates that the Persian version of WHOQOL-HIV BREF is a valid and reliable tool for evaluation of QOL in HIV-infected patients.
authors.affiliation: Department of Community Medicine, School of Medicine, Mashhad University of Medical Science, Mashhad, Islamic Republic of Iran; Research Center for Patient Safety Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran.
authors.forename: M
authors.initials: M
authors.lastname: Salehi
authors.affiliation: Department of Community Medicine, School of Medicine, Mashhad University of Medical Science, Mashhad, Islamic Republic of Iran.
authors.forename: S
authors.initials: S
authors.lastname: Niroumand
authors.affiliation: Department of Community Medicine, School of Medicine, Mashhad University of Medical Science, Mashhad, Islamic Republic of Iran.
authors.forename: M R
authors.initials: MR
authors.lastname: Erfanian
authors.affiliation: Legal Medicine Research Center, Legal Medicine Organization, Mashhad, Islamic Republic of Iran.
authors.forename: R B
authors.initials: RB
authors.lastname: Sajjadi
authors.affiliation: Department of Community Medicine, School of Medicine, Mashhad University of Medical Science, Mashhad, Islamic Republic of Iran.
authors.forename: M
authors.initials: M
authors.lastname: Dadgarmoghaddam
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections; D006306:Health Surveys / Q000592:standards*; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D014944:World Health Organization