title: Fabrication of Artificial Food Bolus for Evaluation of Swallowing.
abstract: Simple and easy methods to evaluate swallowing are required because of the recently increased need of rehabilitation for dysphagia. "Artificial food bolus", but not "artificial food", would be a valuable tool for swallowing evaluation without considering the mastication effect which is altered according to the individual's oral condition. Thus, this study was carried out to fabricate artificial bolus resembling natural food bolus. The mechanical property and the volume change of food bolus in normal people were firstly investigated. Thirty healthy adults without dysphagia were selected and asked to chew four sample foods (rice cake, peanut, burdock, and gummy candy). The results indicated that Young's modulus of bolus before swallowing was below 150 kPa. The bolus volume before swallowing was below 400 mm3. In addition, the saliva component ratio of each bolus was approximately 30wt%, and the average saliva viscosity of research participants was approximately 10 mPa•s. Based on the obtained data, artificial food bolus was designed and fabricated by using alginate hydrogel as a visco-elastic material and gelatin solution as a viscotic material with a ratio of 7:3 based on weight. Consequently, the swallowing time of fabricated artificial food bolus was measured among the same participants. The results indicated the participants swallowed fabricated food bolus with similar manner reflecting their mechanical property and volume. Thus, this artificial food bolus would be a promising tool for evaluation of swallowing.
authors.affiliation: Center for the Special Needs Dentistry, Okayama University Hospital, Shikata-cho, Kita-ku, Okayama, Japan.|Department of Dental Anesthesiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho, Kita-ku, Okayama, Japan.|Department of Biomaterials, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho, Kita-ku, Okayama, Japan.
authors.forename: Miyu
authors.initials: M
authors.lastname: Hosotsubo
authors.affiliation: Center for the Special Needs Dentistry, Okayama University Hospital, Shikata-cho, Kita-ku, Okayama, Japan.|Department of Dental Anesthesiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho, Kita-ku, Okayama, Japan.|Department of Biomaterials, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho, Kita-ku, Okayama, Japan.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Magota
authors.affiliation: Center for the Special Needs Dentistry, Okayama University Hospital, Shikata-cho, Kita-ku, Okayama, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Egusa
authors.affiliation: Department of Dental Anesthesiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho, Kita-ku, Okayama, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Miyawaki
authors.affiliation: Department of Biomaterials, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Shikata-cho, Kita-ku, Okayama, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Matsumoto
mesh_terms: D000328:Adult; D001732:Bite Force; D003679:Deglutition / Q000502:physiology*; D003680:Deglutition Disorders / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D005502:Food; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008409:Mastication / Q000502:physiology*