title: Giant Cell Tumor with Secondary Aneurysmal Bone Cyst Shows Heterogeneous Metabolic Pattern on18F-FDG PET/CT: A Case Report.
abstract: Giant cell tumor (GCT) is a generally benign bone tumor accounting for approximately 5 % of all primary bone neoplasms. Cystic components in GCTs that indicate secondary aneurysmal bone cysts (ABCs) are reported in 14 % of GCTs. Although both of them have been described separately in previous reports that may show considerable fluorodeoxyglucose (FDG) uptake despite their benign nature, the findings of GCT with secondary ABC on18F-FDG positron emission tomography/computed tomography (PET/CT) have not been well-known. We report a case of GCT with secondary ABC in a 26-year-old woman.18F-FDG PET/CT revealed a heterogeneous hypermetabolic lesion in the left proximal femur with the maximum standardized uptake value of 4.7. The solid components of the tumor showed higher FDG uptake than the cystic components. These observations suggest that the ABC components in GCTs show heterogeneous metabolic patterns on18F-FDG PET/CT.
authors.affiliation: Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Huasun-Gun, Republic of Korea.
authors.forename: Hee Jeong
authors.initials: HJ
authors.lastname: Park
authors.affiliation: Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Huasun-Gun, Republic of Korea.
authors.forename: Seong Young
authors.initials: SY
authors.lastname: Kwon
authors.affiliation: Department of Nuclear Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
authors.forename: Sang-Geon
authors.initials: SG
authors.lastname: Cho
authors.affiliation: Department of Nuclear Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
authors.forename: Jahae
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Nuclear Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
authors.forename: Ho-Chun
authors.initials: HC
authors.lastname: Song
authors.affiliation: Department of Pathology, Chonnam National University Hospital, Gwangju, Republic of Korea.
authors.forename: Sung Sun
authors.initials: SS
authors.lastname: Kim
authors.affiliation: Department of Radiology, Chonnam National University Hwasun Hospital, Huasun-Gun, Republic of Korea.
authors.forename: Yeon Hong
authors.initials: YH
authors.lastname: Yoon
authors.affiliation: Department of Radiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
authors.forename: Jin Gyoon
authors.initials: JG
authors.lastname: Park
keywords: 18F-FDG; Aneurysmal bone cyst; Giant cell tumor; PET/CT