title: The treatment of hidradenitis suppurativa with the glucagon-like peptide-1 agonist liraglutide.
abstract: Hidradenitis suppurativa (HS) is a cutaneous disease associated with systemic inflammation, obesity and metabolic syndrome. Effective treatment options are limited. The antidiabetic agents, incretins, have been used successfully to treat psoriasis - a disease also associated with metabolic syndrome. We report the use of liraglutide, a glucagon-like peptide-1 agonist, in a patient with HS, leading to subsequent weight loss and improvement in disease control. To our knowledge, this is the first report of liraglutide used in the treatment of HS.
authors.affiliation: Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland.
authors.forename: L
authors.initials: L
authors.lastname: Jennings
authors.affiliation: Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland.
authors.forename: L
authors.identifier: http://orcid.org/0000-0002-9026-0724
authors.initials: L
authors.lastname: Nestor
authors.affiliation: Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland.
authors.forename: O
authors.initials: O
authors.lastname: Molloy
authors.affiliation: Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland.
authors.forename: R
authors.initials: R
authors.lastname: Hughes
authors.affiliation: Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland.
authors.forename: B
authors.initials: B
authors.lastname: Moriarty
authors.affiliation: Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland.
authors.forename: B
authors.initials: B
authors.lastname: Kirby
mesh_terms: D000328:Adult; D005260:Female; D017497:Hidradenitis Suppurativa / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D000069450:Liraglutide / Q000627:therapeutic use*; D016896:Treatment Outcome; D015431:Weight Loss / Q000187:drug effects
chemical_list: D007004:Hypoglycemic Agents; D000069450:Liraglutide