title: Authors' reply to Pérol and colleagues.
authors.affiliation: Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.|Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland.
authors.forename: Lars G
authors.initials: LG
authors.lastname: Hemkens
authors.affiliation: Department of Pediatrics, Division of Infectious Diseases, Stanford University School of Medicine, Stanford, California, USA.|Meta-Research Innovation Center at Stanford (METRICS).
authors.forename: Despina G
authors.initials: DG
authors.lastname: Contopoulos-Ioannidis
authors.affiliation: Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.|Meta-Research Innovation Center at Stanford (METRICS).|Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA.|Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, California, USA.
authors.forename: John P A
authors.initials: JP
authors.lastname: Ioannidis