title: Crystal structure of vilazodone hydro-chloride methanol monosolvate.
abstract: In the title compound, C26H28N5O2+·Cl-·CH3OH {systematic name: 4-(2-carbamoyl-1-benzo-furan-5-yl)-1-[4-(5-cyano-1H-indol-3-yl)but-yl]piperazin-1-ium chloride methanol monosolvate}, the protonated piperazine ring adopts a chair conformation. The indole ring plane is nearly perpendicular to the benzo-furan ring system, with a dihedral angle of 85.77 (2)°. In the crystal, the organic cations, Cl-anions and methanol solvent mol-ecules are linked by classical N-H⋯O and N-H⋯Cl hydrogen bonds, and weak C-H⋯O and C-H⋯π inter-actions into a three-dimensional supra-molecular architecture.
authors.affiliation: Chemistry Department, Zhejiang University, Hangzhou 310028, People's Republic of China.
authors.forename: Xiu-Rong
authors.initials: XR
authors.lastname: Hu
authors.affiliation: College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China.
authors.forename: Jia-Li
authors.initials: JL
authors.lastname: Ye
authors.affiliation: Chemistry Department, Zhejiang University, Hangzhou 310028, People's Republic of China.
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Gu
keywords: benzo­furan; crystal structure; hydrogen bonds; indole; piperazine