title: Management of veno-occlusive disease: the multidisciplinary approach to care.
abstract: Although it is considered a relatively rare disorder, veno-occlusive disease (VOD) is one of the main causes of overall, non-relapse mortality associated with haematopoietic stem cell transplantation (HSCT). This article, based on the consensus opinion of haemato-oncology nurses, haemato-oncologists and pharmacists from both adult and paediatric services at the VOD International Multi-Disciplinary Advisory Board at the European Society for Blood and Marrow Transplantation (EBMT) meeting, Istanbul, 2015, aims to explore the multidisciplinary approach to care for the management of VOD, with an emphasis on current challenges in this area. The careful monitoring of HSCT patients allows early detection of the symptoms associated with VOD and timely treatment, ultimately improving patient outcomes. As part of a multidisciplinary team, nurses have an essential role to play, from pretransplant assessment to medical management and overall care of the patient. Physicians and pharmacists have a responsibility to facilitate education and training so that nurses can work effectively within that team.
authors.affiliation: Section of Haematology and Coagulation, Department of Internal Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Wallhult
authors.affiliation: Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.
authors.forename: Michelle
authors.initials: M
authors.lastname: Kenyon
authors.affiliation: European Institute of Oncology, Milan, Italy.
authors.forename: Sarah
authors.initials: S
authors.lastname: Liptrott
authors.affiliation: Academic Medical Centre, Amsterdam, The Netherlands.
authors.forename: Arno
authors.initials: A
authors.lastname: Mank
authors.affiliation: National Stem Cell Transplant Unit (Adults), Department of Haematology, St James's Hospital, Dublin, Ireland.
authors.forename: Mairéad
authors.initials: M
authors.lastname: Ní Chonghaile
authors.affiliation: Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Babic
authors.affiliation: UMC Utrecht Cancer Center, Hematologie, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Jacobine
authors.initials: J
authors.lastname: Bijkerk
authors.affiliation: Département d'Hématologie et de Thérapie Cellulaire, CHRU Montpellier-site Saint Eloi, Montpellier, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Bompoint
authors.affiliation: Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Regensburg, Regensburg, Germany.
authors.forename: Selim
authors.initials: S
authors.lastname: Corbacioglu
authors.affiliation: UMC Utrecht Cancer Center, Hematologie, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Roel
authors.initials: R
authors.lastname: de Weijer
authors.affiliation: Klinik für Hämat, Onkol, Klin.Immun., Heinrich Heine Universität, Düsseldorf, Germany.
authors.forename: Claudia
authors.initials: C
authors.lastname: Fink
authors.affiliation: Hematology and BMT Unit, San Raffaele Hospital, Milan, Italy.
authors.forename: Sarah
authors.initials: S
authors.lastname: Marktel
authors.affiliation: Royal Marsden NHS Foundation Trust, Sutton, UK.
authors.forename: Vivek
authors.initials: V
authors.lastname: Soni
authors.affiliation: Department of Stem cell Transplantation, University Hospital Eppendorf, Hamburg, Germany.
authors.forename: Sarah
authors.initials: S
authors.lastname: Sprenger
authors.affiliation: Hospital Universitari I Politècnic la Fe, Oncologia Pediatrica, Valencia, Spain.
authors.forename: Eugenia Trigoso
authors.initials: ET
authors.lastname: Arjona
authors.affiliation: Hematology Department, Hôpital Saint-Antoine, and Université Pierre & Marie Curie, Paris, France.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Mohty
mesh_terms: D000328:Adult; D003226:Congresses as Topic; D032921:Consensus; D004506:Education, Nursing; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods; D009729:Nursing / Q000379:methods*; D011300:Preoperative Care / Q000193:education / Q000379:methods; D014421:Turkey; D014652:Vascular Diseases / Q000209:etiology / Q000401:mortality / Q000517:prevention & control
keywords: bone marrow transplantation; multidisciplinary care; supportive care; veno-occlusive disease