title: Association between sleep duration and the prevalence of atopic dermatitis and asthma in young adults.
abstract: BACKGROUND
  Sleep duration affects allergic diseases; however, this association requires further investigation.
  
  
  OBJECTIVE
  To evaluate the association between sleep duration and the prevalence of atopic dermatitis and asthma in young Korean adults.
  
  
  METHODS
  We analyzed data of 10,148 subjects (4,239 men; 5,909 women) aged 19-39 years from the Korean National Health and Nutrition Examination Survey 2008-2010. Self-reported sleep duration was categorized into five groups: ≤5h, 6h, 7h, 8h, and ≥9h. The prevalence of atopic dermatitis and asthma was examined based on a questionnaire and compared between participants from five sleep duration groups after adjusting for potential confounding factors, including model 1 [age], model 2 [model 1 + BMI, current smoking, current alcohol use, regular physical activity, household income, and serum 25(OH)D level], and model 3 [model 2 + stress levels].
  
  
  RESULTS
  In female participants, a higher risk of atopic dermatitis was associated with sleep duration ≤5 hours [odds ratio (OR): 1.665, 95% confidence interval (CI): 1.004-2.762; model 1], and ≥9 hours (OR, 1.746, 95% CI, 1.145-2.661; model 3), compared to a 7-hour sleep duration. Similarly, a higher risk of asthma was associated with sleep duration ≤5 hours and ≥9 hours (OR, 1.553, 95% CI, 1.023-2.359 and OR, 1.569, 95% CI, 1.048-2.349, respectively; model 3). In male participants, there was no significant association between sleep duration and the prevalence of atopic dermatitis or asthma.
  
  
  CONCLUSIONS
  Sleep duration ≤5 and ≥9 hours may be a risk factor for atopic dermatitis and asthma in young female adults.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Republic of Korea.
authors.forename: Ji Ho
authors.initials: JH
authors.lastname: Choi
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, Republic of Korea.
authors.forename: Ga Eun
authors.initials: GE
authors.lastname: Nam
authors.affiliation: Department of Family Medicine, Korea University College of Medicine, Seoul, Republic of Korea.
authors.forename: Do Hoon
authors.initials: DH
authors.lastname: Kim
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Republic of Korea.
authors.forename: Jae Yong
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Biostatistics, Catholic University College of Medicine, Seoul, Republic of Korea.
authors.forename: Kyung Do
authors.initials: KD
authors.lastname: Han
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Konkuk University, Seoul, Republic of Korea.
authors.forename: Jae Hoon
authors.initials: JH
authors.lastname: Cho
mesh_terms: D000328:Adult; D001249:Asthma / Q000453:epidemiology* / Q000209:etiology*; D003876:Dermatitis, Atopic / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D016017:Odds Ratio; D011159:Population Surveillance; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012890:Sleep; D012959:Socioeconomic Factors; D055815:Young Adult