title: Population genetic data for ten miniSTR loci in the Sri Lankan population.
abstract: Allele frequencies and forensically important parameters of ten autosomal miniSTR loci, D1S1677, D2S1776, D10S1248, D11S4463, D12SATA, D14S1434, D17S974, D18S853, D20S482, and D22S1045, were obtained for 278 unrelated adults from the Sri Lankan population. The combined power of discrimination and probability of exclusion was found to be 0.999999999621539 and 0.9979620, respectively. No significant deviations from Hardy-Weinberg equilibrium were observed except for D20S482 which conformed to HW expectations only after the application of a Bonferroni correction. The study suggests the potential use of these miniSTRs as a supplement or as a stand-alone STR marker system for the analysis of highly degraded evidence in Sri Lanka.
authors.affiliation: Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka. suraj@genetechsrilanka.com.|Department of Zoology, University of Colombo, Colombo, 03, Sri Lanka. suraj@genetechsrilanka.com.
authors.forename: N D S
authors.initials: NDS
authors.lastname: Goonawardhana
authors.affiliation: Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka.
authors.forename: G S K W
authors.initials: GSKW
authors.lastname: Jayasekara
authors.affiliation: Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka.
authors.forename: V
authors.initials: V
authors.lastname: Elanahai
authors.affiliation: Department of Zoology, University of Colombo, Colombo, 03, Sri Lanka.
authors.forename: P V
authors.initials: PV
authors.lastname: Udagama
authors.affiliation: Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka.
authors.forename: N D
authors.initials: ND
authors.lastname: Fernandopulle
mesh_terms: D016172:DNA Fingerprinting; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction; D013188:Sri Lanka
keywords: Degraded DNA; Miniaturized short tandem repeats (miniSTR); Sinhalese; Sri Lankan Moors; Sri Lankan Tamils