title: Recurrent episodes of Candidemia due toCandida glabrata, Candida tropicalisandCandida albicanswith acquired echinocandin resistance.
abstract: Mixed fungal infection and acquired echinocandin resistance ofCandidaspp. remain infrequent. In this study we have reported the case of a patient hospitalized for tuberculosis who experienced multiple infections due to three commonCandidaspecies (C. albicans, C. glabrata, C. tropicalis). Furthermore, consecutive isolates from blood cultures and heart valve were found resistant to azoles (C. tropicalis) and to echinocandin with either novel (C. tropicalis) or previously described (C. albicans) missense mutations in theFksgene.
authors.affiliation: Service de Maladies Infectieuses et tropicales, CHU de Poitiers, 2 rue de la Milétrie, Poitiers 86021, France.
authors.forename: Marine
authors.initials: M
authors.lastname: Grosset
authors.affiliation: Institut Pasteur, Unité de Mycologie Moléculaire, Centre National de Référence Mycologie et Antifongiques, 25 rue du Dr Roux, Paris 75015, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Desnos-Ollivier
authors.affiliation: Service de Maladies Infectieuses et tropicales, CHU de Poitiers, 2 rue de la Milétrie, Poitiers 86021, France.
authors.forename: Cendrine
authors.initials: C
authors.lastname: Godet
authors.affiliation: Laboratoire de Parasitologie Mycologie, CHU de Poitiers, 2 rue de la Milétrie, Poitiers 86021, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Kauffmann-Lacroix
authors.affiliation: Service de Maladies Infectieuses et tropicales, CHU de Poitiers, 2 rue de la Milétrie, Poitiers 86021, France.
authors.forename: France
authors.initials: F
authors.lastname: Cazenave-Roblot
keywords: Candidemia; Echinocandin resistance; Endocarditis; Fks mutation; Mixed infection; Multiresistance