title: Clinical Trials in FSGS: Past Challenges and New Trial Designs.
authors.affiliation: Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, MI. Electronic address: dgipson@med.umich.edu.
authors.forename: Deb
authors.initials: D
authors.lastname: Gipson
mesh_terms: D000075522:Adaptive Clinical Trials as Topic; D000328:Adult; D002648:Child; D002986:Clinical Trials as Topic; D016572:Cyclosporine / Q000627:therapeutic use; D018450:Disease Progression; D005919:Glomerular Filtration Rate; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications / Q000188:drug therapy*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D009173:Mycophenolic Acid / Q000627:therapeutic use; D009404:Nephrotic Syndrome / Q000150:complications / Q000188:drug therapy*; D000071066:Patient Reported Outcome Measures; D011507:Proteinuria / Q000188:drug therapy* / Q000209:etiology; D012107:Research Design
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D009173:Mycophenolic Acid
keywords: Adaptive trials; consortium; kidney disease; nephrotic syndrome; patient-reported outcomes; proteinuria