title: Tunable Aggregation-Induced Emission of Polyoxometalates via Amino Acid-Directed Self-Assembly and Their Application in Detecting Dopamine.
abstract: In this work, through the aqueous phase self-assembly of an Eu-containing polyoxometalate (POM), Na9[EuW10O36]·32H2O (EuW10) and different amino acids, we obtained spontaneously formed vesicles that showed luminescence enhancement for EuW10and arginine (Arg), lysine (Lys), or histidine (His) complexes, but luminescence quenching for EuW10and glutamic acid (Glu) or aspartic acid (Asp) complexes. The binding mechanisms between them have been explored at the molecular level by using different characterization techniques. It was found that EuW10acted as polar head groups interact with the positively charged residues for alkaline amino acids, protonated amide groups for acidic amino and nonpolar acid aminos through electrostatic interactions, and the remaining segments of amino acids served as relatively hydrophobic parts aggregated together forming bilayer membrane structures. Moreover, the different influences of amino acids on the fluorescence property of EuW10revealed that the electrostatic interaction between the positive charged group of amino acid and the polyanionic cluster dominates the fluorescence properties of assemblies. Furthermore, a turn-off sensing application of the EuW10/Arg platform to probe dopamine (DA) against various other biological molecules such as neurotransmitters or amino acids was also established. The concept of combining POMs with amino acids extends the research category of POM-based functional materials and devices.
authors.affiliation: Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, People's Republic of China.
authors.forename: Han
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, People's Republic of China.
authors.forename: Lingyu
authors.initials: L
authors.lastname: Guo
authors.affiliation: National Engineering Technology Research Center for Colloidal Materials, Shandong University , Jinan, 250100, People's Republic of China.
authors.forename: Zengchun
authors.initials: Z
authors.lastname: Xie
authors.affiliation: Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, People's Republic of China.|National Engineering Technology Research Center for Colloidal Materials, Shandong University , Jinan, 250100, People's Republic of China.
authors.forename: Xia
authors.identifier: 0000-0002-4886-6028
authors.initials: X
authors.lastname: Xin
authors.affiliation: Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, People's Republic of China.
authors.forename: Di
authors.initials: D
authors.lastname: Sun
authors.affiliation: Key Lab for Colloid and Interface Chemistry of Education Ministry, School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, People's Republic of China.
authors.forename: Shiling
authors.initials: S
authors.lastname: Yuan
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D004298:Dopamine / Q000032:analysis*; D017973:Tungsten Compounds / Q000737:chemistry*; D000099294:Polyoxometalates
chemical_list: D000596:Amino Acids; D004298:Dopamine; D017973:Tungsten Compounds; C102296:polyoxometalate I; D000099294:Polyoxometalates