title: Hyponatraemia-induced rhabdomyolysis complicated by anuric acute kidney injury: a renal replacement conundrum.
abstract: Hyponatraemia-induced rhabdomyolysis is a rare, but reported phenomenon, particularly in patients with chronic schizophrenia on depot antipsychotics prone to psychogenic polydipsia. To the best of our knowledge, there are no reported cases of hyponatraemia-induced rhabdomyolysis complicated by oligo-anuric acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). The initiation of CRRT is complicated in severe hyponatraemia, predominantly due to the need to avoid rapid changes in tonicity associated with rapid changes in sodium. We report a case of severe hyponatraemia (104 mmol/L) complicated by oligo-anuric rhabdomyolysis-induced AKI and our management of the renal prescription.
authors.affiliation: Faculty of Health and Medical Sciences, University of Adelaide, The Joanna Briggs Institute, Adelaide, South Australia, Australia.|Department of Intensive Care, Alice Springs Hospital, Alice Springs, Australia.
authors.forename: Paul
authors.identifier: http://orcid.org/0000-0002-1137-0512
authors.initials: P
authors.lastname: Secombe
authors.affiliation: Department of Intensive Care, Alice Springs Hospital, Alice Springs, Australia.
authors.forename: Chris
authors.initials: C
authors.lastname: Milne
mesh_terms: D058186:Acute Kidney Injury / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D001002:Anuria / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007010:Hyponatremia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D017582:Renal Replacement Therapy / Q000379:methods*; D012206:Rhabdomyolysis / Q000150:complications* / Q000175:diagnosis / Q000209:etiology