title: Why proteomics is not the new genomics and the future of mass spectrometry in cell biology.
abstract: Mass spectrometry (MS) is an essential part of the cell biologist's proteomics toolkit, allowing analyses at molecular and system-wide scales. However, proteomics still lag behind genomics in popularity and ease of use. We discuss key differences between MS-based -omics and other booming -omics technologies and highlight what we view as the future of MS and its role in our increasingly deep understanding of cell biology.
authors.affiliation: Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
authors.forename: Simone
authors.initials: S
authors.lastname: Sidoli
authors.affiliation: Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.|Division of Cancer Pathobiology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kulej
authors.affiliation: Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 bgarci@mail.med.upenn.edu.
authors.forename: Benjamin A
authors.initials: BA
authors.lastname: Garcia
mesh_terms: D000818:Animals; D003585:Cell Biology / Q000639:trends*; D004059:Diffusion of Innovation; D005544:Forecasting; D023281:Genomics / Q000639:trends*; D006801:Humans; D013058:Mass Spectrometry / Q000639:trends*; D040901:Proteomics / Q000639:trends*; D015203:Reproducibility of Results