title: Fluorescence detection of endogenous bisulfite in liver cancer cells using an effective ESIPT enhanced FRET platform.
abstract: Probe L-HF1, which featured large (pseudo) Stokes shifts and high FRET efficiency, was designed on a new ESIPT enhanced FRET platform for the detection of HSO3-/SO32-. L-HF1 could detect endogenous bisulfite in HepG2 cells but not in L-02 cells, implying the different bisulfite levels in normal and cancer cells of liver.
authors.affiliation: School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China. bxzhao@sdu.edu.cn.
authors.forename: Dong-Peng
authors.initials: DP
authors.lastname: Li
authors.affiliation: Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, P. R. China. miaojy@sdu.edu.cn.
authors.forename: Zhao-Yang
authors.initials: ZY
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China. bxzhao@sdu.edu.cn.
authors.forename: Hao
authors.initials: H
authors.lastname: Su
authors.affiliation: Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, P. R. China. miaojy@sdu.edu.cn.
authors.forename: Jun-Ying
authors.initials: JY
authors.lastname: Miao
authors.affiliation: School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China. bxzhao@sdu.edu.cn.
authors.forename: Bao-Xiang
authors.initials: BX
authors.lastname: Zhao
mesh_terms: D005419:Flavonoids / Q000737:chemistry*; D005453:Fluorescence; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry*; D056945:Hep G2 Cells; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D015394:Molecular Structure; D011522:Protons; D013050:Spectrometry, Fluorescence; D013447:Sulfites / Q000032:analysis*
chemical_list: D005419:Flavonoids; D005456:Fluorescent Dyes; D011522:Protons; D013447:Sulfites; C042345:hydrogen sulfite; C041477:3-hydroxyflavone