title: Prevalence of hypertension and other cardiovascular risk factors in subjects with subclinical hypothyroidism.
abstract: OBJECTIVE
  To assess the prevalence of hypertension, diabetes, and dyslipidaemia in subjects with subclinical hypothyroidism (SH) in comparison with an age- and sex-matched control group.
  
  
  METHODS
  Case-control study with 240 subjects with SH and 480 controls carried out on patients aged 35-75 years admitted to a Primary Care Centre. The prevalence of hypertension, diabetes and dyslipidaemia, as well as blood pressure, plasma glucose, and lipid profilses, were evaluated in both groups.
  
  
  RESULTS
  No differences were observed neither in the prevalence of hypertension (34.2% vs. 29.6%) or diabetes (12.1% vs. 10%) nor in mean values of blood pressure or plasma fasting glucose. Subjects with SH had an increased prevalence of lipid abnormalities (72.1% vs. 57.7%; P<.001), and increased mean values of total cholesterol (205±34 vs. 193±35mg/dL; P<.001), compared to the control group.
  
  
  CONCLUSIONS
  Patients with SH have an increased prevalence of lipid abnormalities. This can be responsible for an increased cardiovascular risk in such patients.
authors.affiliation: Centro Atención Primaria CAP Rambla de Terrassa, Mutua Terrassa, Barcelona, España.
authors.forename: Lidia
authors.initials: L
authors.lastname: Gonzalez Gil
authors.affiliation: Servicio de Medicina Interna, Hospital Mutua Terrassa, Universidad de Barcelona, Barcelona, España. Electronic address: adelasierra@mutuaterrassa.cat.
authors.forename: Alejandro
authors.initials: A
authors.lastname: de la Sierra
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000209:etiology*; D050171:Dyslipidemias / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000209:etiology*; D007037:Hypothyroidism / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Arterial hypertension; Dislipidemia; Dyslipidaemia; Hipertensión arterial; Hipotiroidismo subclínico; Subclinical hypothyroidism