title: Effects of face cooling on pulse waveform and sympathetic activity in hypertensive subjects.
abstract: Adverse cardiovascular events occur more frequently during cold weather. To test the hypothesis that cold exposure would lead to increased sympathetic activity and impaired hemodynamic control, we measured muscle sympathetic nerve activity and hemodynamic parameters in nine men with hypertension before and during trigeminal stimulation and facial cooling. The procedure increased blood pressure (p < 0.01), aortic hemodynamic parameters (p < 0.01), and muscle sympathetic nerve activity (p < 0.05). These results suggest that sympathetic activation during cold exposure in hypertensive subjects may increase the risk of cardiovascular events during cold weather.
authors.affiliation: Laboratory of Exercise Sciences, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil.
authors.forename: Eliza
authors.identifier: 0000-0003-2700-0409
authors.initials: E
authors.lastname: Prodel
authors.affiliation: Laboratory of Exercise Sciences, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil.
authors.forename: Thales C
authors.initials: TC
authors.lastname: Barbosa
authors.affiliation: Laboratory of Exercise Sciences, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil.
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Mansur
authors.affiliation: Laboratory of Exercise Sciences, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil.
authors.forename: Antonio Claudio L
authors.initials: AC
authors.lastname: Nóbrega
authors.affiliation: Laboratory of Exercise Sciences, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil. lcvianna@unb.br.|NeuroVASQ-Integrative Physiology Lab, Faculty of Physical Education, University of Brasília, Asa Norte, Brasília, DF, 70910900, Brazil. lcvianna@unb.br.
authors.forename: Lauro C
authors.initials: LC
authors.lastname: Vianna
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D003080:Cold Temperature / Q000009:adverse effects*; D005154:Facial Nerve / Q000503:physiopathology*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis / Q000379:methods; D013564:Sympathetic Nervous System / Q000503:physiopathology
keywords: Blood pressure; Hemodynamics; Hypertension; Trigeminal nerve