title: Annular pustular psoriasis in a 14-month-old girl: a therapeutic challenge.
abstract: Annular pustular psoriasis (annular PP) is a rare but severe variant of psoriasis, which may even occur in early childhood. At this age, therapeutic options are limited and medication issues can be challenging. We report clinical features, diagnostic findings and treatment of an 11-month-old girl with annular PP. Oral acitretin therapy was initiated at 0.9 mg/kg/d and gradually tapered after complete resolution in the subsequent 10 months without relapse. Acitretin proved to be a highly effective therapeutic option in an infant with annular PP.
authors.affiliation: a Department of Dermatology, Venereology and Allergology , University Hospital Würzburg , Würzburg , Germany.
authors.forename: Victoria
authors.initials: V
authors.lastname: Haug
authors.affiliation: a Department of Dermatology, Venereology and Allergology , University Hospital Würzburg , Würzburg , Germany.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Benoit
authors.affiliation: b Department of Pediatrics , University Hospital Würzburg , Würzburg , Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Wohlleben
authors.affiliation: a Department of Dermatology, Venereology and Allergology , University Hospital Würzburg , Würzburg , Germany.
authors.forename: Henning
authors.initials: H
authors.lastname: Hamm
mesh_terms: D017255:Acitretin / Q000627:therapeutic use*; D000284:Administration, Oral; D000287:Administration, Topical; D005260:Female; D006801:Humans; D007223:Infant; D007641:Keratolytic Agents / Q000627:therapeutic use*; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology; D012720:Severity of Illness Index; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D007641:Keratolytic Agents; D011239:Prednisolone; D017255:Acitretin; C035287:prednicarbate
keywords: Acitretin; annular pustular psoriasis; children; psoriasis; psoriasis of erythema annulare centrifugum-type