title: Versatile Loading of Diverse Cargo into Functional Polymer Capsules.
abstract: Polymer microcapsules are of particular interest for applications including self-healing coatings, catalysis, bioreactions, sensing, and drug delivery. The primary way that polymer capsules can exhibit functionality relevant to these diverse fields is through the incorporation of functional cargo in the capsule cavity or wall. Diverse functional and therapeutic cargo can be loaded into polymer capsules with ease using polymer-stabilized calcium carbonate (CaCO3) particles. A variety of examples are demonstrated, including 15 types of cargo, yielding a toolbox with effectively 500+ variations. This process uses no harsh reagents and can take less than 30 min to prepare, load, coat, and form the hollow capsules. For these reasons, it is expected that the technique will play a crucial role across scientific studies in numerous fields.
authors.affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia.
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Richardson
authors.affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia.
authors.forename: James W
authors.initials: JW
authors.lastname: Maina
authors.affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia.
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Ejima
authors.affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia.
authors.forename: Ming
authors.initials: M
authors.lastname: Hu
authors.affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia.
authors.forename: Junling
authors.initials: J
authors.lastname: Guo
authors.affiliation: Vascular Biotechnology Laboratory Baker IDI Heart and Diabetes Institute Melbourne Australia.
authors.forename: Mei Y
authors.initials: MY
authors.lastname: Choy
authors.affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia.
authors.forename: Sylvia T
authors.initials: ST
authors.lastname: Gunawan
authors.affiliation: Department of Pharmaceutics Ghent University Ghent Belgium.
authors.forename: Lien
authors.initials: L
authors.lastname: Lybaert
authors.affiliation: Vascular Biotechnology Laboratory Baker IDI Heart and Diabetes Institute Melbourne Australia.
authors.forename: Christoph E
authors.initials: CE
authors.lastname: Hagemeyer
authors.affiliation: Department of Pharmaceutics Ghent University Ghent Belgium.
authors.forename: Bruno G
authors.initials: BG
authors.lastname: De Geest
authors.affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia.
authors.forename: Frank
authors.initials: F
authors.lastname: Caruso
keywords: drug delivery; drug loading; inorganic templates; nanomedicine; polymer capsules