title: Is Laparoendoscopic Single-Site Adrenalectomy a Feasible Alternative in Treating Aldosterone-Producing Adenoma?
abstract: Objective. To compare laparoendoscopic single-site (LESS) and conventional multiport adrenalectomy in patients with aldosterone-producing adenoma (APA).Material and Methods. We retrospectively reviewed patients who had been clinically confirmed with unilateral APA and who underwent LESS or multiport adrenalectomy between 2009 and 2014. Perioperative data were obtained for all patients. Blood pressure and the levels of serum aldosterone, renin, and potassium were checked periodically.Results. We identified 45 APA patients in the LESS group and 71 in the multiport group. The baseline characteristics were matched between two groups. All adrenalectomies were completed successfully, except one with laparoscopic conversion in the single-port group and one open conversion in the multiport group. After a mean follow-up around one year, there were no significant group differences in the improvement of hypertension, number of types of medication taken, and cure of hypokalemia after operation.Conclusions. Our study confirm that LESS adrenalectomy achieved similar clinical and functional outcomes as conventional multiport adrenalectomy for management of unilateral APA.
authors.affiliation: Division of Nephrology, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan.
authors.forename: Che-Hsiung
authors.initials: CH
authors.lastname: Wu
authors.affiliation: Division of Endocrine and Metabolism, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan.
authors.forename: Leay-Kiaw
authors.initials: LK
authors.lastname: Er
authors.affiliation: Division of Endocrine and Metabolism, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan.
authors.forename: Ya-Hui
authors.initials: YH
authors.lastname: Hu
authors.affiliation: Department of Surgery, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan; Department of Urology, Tzu Chi University, Medical College, Hualien, Taiwan.
authors.forename: Chia Da
authors.initials: CD
authors.lastname: Lin
authors.affiliation: Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Shih-Chieh
authors.identifier: 0000-0002-0713-4904
authors.initials: SC
authors.lastname: Chueh
authors.affiliation: Department of Surgery, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan; Department of Urology, Tzu Chi University, Medical College, Hualien, Taiwan.
authors.forename: Yao-Chou
authors.identifier: 0000-0002-2833-5609
authors.initials: YC
authors.lastname: Tsai
mesh_terms: D000236:Adenoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D000310:Adrenal Gland Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications* / Q000473:pathology; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome