title: Rh-Catalyzed Asymmetric Hydrogenation of 1,2-Dicyanoalkenes.
abstract: A highly efficient enantioselective hydrogenation of 1,2-dicyanoalkenes catalyzed by the complex of rhodium and f-spiroPhos has been developed. A series of 1,2-dicyanoalkenes were successfully hydrogenated to the corresponding chiral 1,2-dicyanoalkanes under mild conditions with excellent enantioselectivities (up to 98% ee). This methodology provides efficient access to the asymmetric synthesis of chiral diamines.
authors.affiliation: Key Laboratory of Radiopharmaceuticals, College of Chemistry, Beijing Normal University , Beijing 100875, China.
authors.forename: Meina
authors.initials: M
authors.lastname: Li
authors.affiliation: Key Laboratory of Radiopharmaceuticals, College of Chemistry, Beijing Normal University , Beijing 100875, China.
authors.forename: Duanyang
authors.initials: D
authors.lastname: Kong
authors.affiliation: Key Laboratory of Radiopharmaceuticals, College of Chemistry, Beijing Normal University , Beijing 100875, China.
authors.forename: Guofu
authors.initials: G
authors.lastname: Zi
authors.affiliation: Key Laboratory of Radiopharmaceuticals, College of Chemistry, Beijing Normal University , Beijing 100875, China.
authors.forename: Guohua
authors.identifier: 0000-0002-3571-456X
authors.initials: G
authors.lastname: Hou