title: Effect of preconditioning cobalt and nickel based dental alloys with Bacillus sp. extract on their surface physicochemical properties and theoretical prediction of Candida albicans adhesion.
abstract: Biofilm formation on dental biomaterials is implicated in various oral health problems. Thus the challenge is to prevent the formation of this consortium of microorganisms using a safe approach such as antimicrobial and anti-adhesive natural products. Indeed, in the present study, the effects of an antifungal extract of Bacillus sp., isolated from plant rhizosphere, on the surface physicochemical properties of cobalt and nickel based dental alloys were studied using the contact angle measurements. Furthermore, in order to predict the adhesion of Candida albicans to the treated and untreated dental alloys, the total free energy of adhesion was calculated based on the extended Derjaguin-Landau-Verwey-Overbeek approach. Results showed hydrophobic and weak electron-donor and electron-acceptor characteristics of both untreated dental alloys. After treatment with the antifungal extract, the surface free energy of both dental alloys was influenced significantly, mostly for cobalt based alloy. In fact, treated cobalt based alloy became hydrophilic and predominantly electron donating. Those effects were time-dependent. Consequently, the total free energy of adhesion of C. albicans to this alloy became unfavorable after treatment with the investigated microbial extract. A linear relationship between the electron-donor property and the total free energy of adhesion has been found for both dental alloys. Also, a linear relationship has been found between this latter and the hydrophobicity for the cobalt based alloy. However, the exposure of nickel based alloy to the antifungal extract failed to produce the same effect.
authors.affiliation: Faculté des Sciences et Techniques, Université Sidi Mohamed Ben Abdellah, BP 2202, 30007 Fez, Morocco. Electronic address: b.mounyr@gmail.com.
authors.forename: Mounyr
authors.initials: M
authors.lastname: Balouiri
authors.affiliation: Faculté des Sciences de Tétouan, Université Abdelmalek Essaadi, Avenue de Sebta, Mhannech II, 93002 Tétouan, Morocco.
authors.forename: Samira
authors.initials: S
authors.lastname: Bouhdid
authors.affiliation: Faculté des Sciences et Techniques, Université Sidi Mohamed Ben Abdellah, BP 2202, 30007 Fez, Morocco.
authors.forename: Moulay
authors.initials: M
authors.lastname: Sadiki
authors.affiliation: Faculté des Sciences et Techniques, Université Sidi Mohamed Ben Abdellah, BP 2202, 30007 Fez, Morocco.
authors.forename: Wessal
authors.initials: W
authors.lastname: Ouedrhiri
authors.affiliation: Faculté des Sciences et Techniques, Université Sidi Mohamed Ben Abdellah, BP 2202, 30007 Fez, Morocco.
authors.forename: Hassan
authors.initials: H
authors.lastname: Barkai
authors.affiliation: Faculté des Sciences et Techniques, Université Sidi Mohamed Ben Abdellah, BP 2202, 30007 Fez, Morocco.
authors.forename: Omar
authors.initials: O
authors.lastname: El Farricha
authors.affiliation: Faculté des Sciences et Techniques, Université Sidi Mohamed Ben Abdellah, BP 2202, 30007 Fez, Morocco; Cité de l'innovation, Université Sidi Mohamed Ben Abdellah, BP 2626, 30007 Fez, Morocco.
authors.forename: Saad Koraichi
authors.initials: SK
authors.lastname: Ibnsouda
authors.affiliation: Faculté des Sciences et Techniques, Université Sidi Mohamed Ben Abdellah, BP 2202, 30007 Fez, Morocco.
authors.forename: El Houssaine
authors.initials: EH
authors.lastname: Harki
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D001407:Bacillus / Q000737:chemistry*; D002176:Candida albicans / Q000254:growth & development*; D003035:Cobalt / Q000737:chemistry / Q000494:pharmacology; D003722:Dental Alloys / Q000737:chemistry / Q000494:pharmacology; D009532:Nickel / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D003722:Dental Alloys; D003035:Cobalt; D009532:Nickel
keywords: Anti-adhesive; Bacillus extract; Candida albicans; Dental alloy; Physicochemical property