title: Neuro-Behcet disease presenting as a solitary cerebellar hemorrhagic lesion: a case report and review of the literature.
abstract: BACKGROUND
  Behcet's disease is a heterogeneous, multisystem, inflammatory disorder of unknown etiology. The classic triad of oral and genital ulcerations in conjunction with uveitis was originally described by the Turkish dermatologist Hulusi Behcet in 1937, but associated symptoms of the cardiovascular, central nervous, pulmonary, and gastrointestinal systems were later identified. In fact, Behcet's disease with neurological involvement (neuro-Behcet's disease) is not uncommon. Patients with neuro-Behcet's disease typically exhibit a diverse array of symptoms, most commonly in the brainstem and diencephalic regions. Herein, we report an unusual case of neuro-Behcet's disease in a patient who presented with a solitary cerebellar hemorrhage.
  
  
  METHODS
  A 39-year-old Asian woman was admitted to our hospital with complaints of a sudden speech difficulty that had manifested the same morning, and dizziness and mild vomiting experienced over the previous 3 days. Magnetic resonance images revealed target-like hemorrhagic lesions in the right hemisphere of the cerebellum. Risk factors that may result in cerebellar hemorrhage, such as high blood pressure or bleeding diathesis, were ruled out, and subsequent brain angiograms were normal.
  
  
  CONCLUSIONS
  These findings suggest that the patient's cerebellar hemorrhage could have been due to intracranial vasculitis in a rare, if not unique, complication of neuro-Behcet's disease.
authors.affiliation: Department of Neurology, Chungbuk National University College of Medicine, Chungbuk National University Hospital, 776 1Sunhwan-ro, Seowon-ku, Cheongju-si, Chungbuk, 361-711, South Korea.
authors.forename: Minju
authors.initials: M
authors.lastname: Yeo
authors.affiliation: Department of Neurology, Chungbuk National University College of Medicine, Chungbuk National University Hospital, 776 1Sunhwan-ro, Seowon-ku, Cheongju-si, Chungbuk, 361-711, South Korea.
authors.forename: Hye-Lim
authors.initials: HL
authors.lastname: Lee
authors.affiliation: Department of Neurology, Chungbuk National University College of Medicine, Chungbuk National University Hospital, 776 1Sunhwan-ro, Seowon-ku, Cheongju-si, Chungbuk, 361-711, South Korea.
authors.forename: Minju
authors.initials: M
authors.lastname: Cha
authors.affiliation: Department of Neurology, Chungbuk National University College of Medicine, Chungbuk National University Hospital, 776 1Sunhwan-ro, Seowon-ku, Cheongju-si, Chungbuk, 361-711, South Korea.
authors.forename: Ji Seon
authors.initials: JS
authors.lastname: Kim
authors.affiliation: Department of Neurology, Yuseong Sun General Hospital, DaeJeon, 34084, South Korea.
authors.forename: Ho-Seong
authors.initials: HS
authors.lastname: Han
authors.affiliation: Department of Neurology, Chungbuk National University College of Medicine, Chungbuk National University Hospital, 776 1Sunhwan-ro, Seowon-ku, Cheongju-si, Chungbuk, 361-711, South Korea.
authors.forename: Sung-Hyun
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Neurology, Chungbuk National University College of Medicine, Chungbuk National University Hospital, 776 1Sunhwan-ro, Seowon-ku, Cheongju-si, Chungbuk, 361-711, South Korea.
authors.forename: Sang-Soo
authors.initials: SS
authors.lastname: Lee
authors.affiliation: Department of Neurology, Chungbuk National University College of Medicine, Chungbuk National University Hospital, 776 1Sunhwan-ro, Seowon-ku, Cheongju-si, Chungbuk, 361-711, South Korea. sdi007@hanmail.net.
authors.forename: Dong-Ick
authors.initials: DI
authors.lastname: Shin
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D044466:Asian People; D001528:Behcet Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002526:Cerebellar Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy; D002531:Cerebellum / Q000098:blood supply*; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use*; D013064:Speech Disorders / Q000000981:diagnostic imaging* / Q000209:etiology; D016896:Treatment Outcome; D014839:Vomiting
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone
keywords: Behcet’s disease; Case report; Intracerebellar hemorrhage; Neuro-Behcet’s disease