title: The relationship of mean platelet volume with retinopathy in type 2 diabetes mellitus.
abstract: OBJECTIVE
  Patients with diabetes mellitus have an increased risk of developing micro- and macrovascular complications. Retinopathy is one of the most important complications of diabetes whose pathophysiological cause has not yet been determined. One candidate may be platelet volume. In this study we aimed to investigate the association between mean platelet volume and diabetic retinopathy.
  
  
  METHODS
  Mean platelet volume levels were investigated in type 2 diabetic patients with and without retinopathy, and in healthy participants. After reclassifying our diabetics in terms of the presence or absence of hypertension and hyperlipidemia, we compared their mean platelet volumes. We then checked to see if the mean platelet volume correlated with hemoglobin A1c and body mass index.
  
  
  RESULTS
  The mean platelet volume levels were higher in all diabetic patients, and they were highest in diabetics with retinopathy. The mean platelet volume levels were not different in diabetic patients with and without hypertension or hyperlipidemia. Moreover, the mean platelet volume levels did not correlate with hemoglobin A1c or body mass index.
  
  
  CONCLUSIONS
  We think that platelets may play a role in diabetic retinopathy. We can also say that, in diabetic patients, hypertension, hyperlipemia, obesity, and control of diabetes were not related to mean platelet volume.
authors.affiliation: Department of Internal Medicine, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Aslı Araz
authors.initials: AA
authors.lastname: Güngör
authors.affiliation: Department of Internal Medicine, Kafkas University, Kars, Turkey.
authors.forename: Gül
authors.initials: G
authors.lastname: Gürsoy
authors.affiliation: Department of Internal Medicine, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Güngör
authors.affiliation: Department of Internal Medicine, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Seyit Murat
authors.initials: SM
authors.lastname: Bayram
authors.affiliation: Department of Internal Medicine, Kafkas University, Kars, Turkey.
authors.forename: Eray
authors.initials: E
authors.lastname: Atalay
mesh_terms: D001786:Blood Glucose; D003924:Diabetes Mellitus, Type 2; D003930:Diabetic Retinopathy; D006442:Glycated Hemoglobin; D006801:Humans; D063847:Mean Platelet Volume
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin
keywords: Retinopathy; mean platelet volume; type 2 diabetes mellitus