title: TiCl4/Et3N-Mediated Condensation of Acetate and Formate Esters: Direct Access to β-Alkoxy- and β-Aryloxyacrylates.
abstract: A methodology to build (E)-β-alkoxy- and (E)-β-aryloxyacrylate moieties from acetate and formate esters promoted by the TiCl4/Et3N system is presented. The reaction is compatible with a broad range of structural skeletons and elapses through an unusual condensation pathway. Taking into account the obtained results, we propose a plausible mechanism involving a bimetallic titanium intermediate for this type of transformation.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz , Puerto Real, 11510 Cádiz, Spain.
authors.forename: José María
authors.initials: JM
authors.lastname: Álvarez-Calero
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz , Puerto Real, 11510 Cádiz, Spain.
authors.forename: Zacarías D
authors.initials: ZD
authors.lastname: Jorge
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz , Puerto Real, 11510 Cádiz, Spain.
authors.forename: Guillermo M
authors.identifier: 0000-0002-7463-5696
authors.initials: GM
authors.lastname: Massanet