title: Inhibitory effect of sugarcane molasses extract on the formation of Nε-(carboxymethyl)lysine and Nε-(carboxyethyl)lysine.
abstract: Molasses, the main byproduct of sugar production, is a well-known source of phenolic compounds. In this study, the effect of sugarcane molasses extract on the formation of Nε-(carboxymethyl)lysine (CML) and Nε-(carboxyethyl)lysine (CEL) was investigated in glucose-lysine model reaction systems. Results showed that sugarcane molasses extract significantly and dose dependently inhibited the formation of CML and CEL in model reaction systems. The antiglycation activities of sugarcane molasses extract were not only brought about by its antioxidant activities but also associated with its trapping abilities of reactive carbonyl species, such as glyoxal (GO) and methylglyoxal (MGO), the key intermediate compound for the formation of CML and CEL. Besides, the presence of sugarcane molasses extract effectively reduced the extent of browning. The present study emphasized the potential health effects of sugarcane molasses and the possibility of using byproducts as effective ingredients to reduce dietary Maillard reaction end products.
authors.affiliation: School of Food science and Engineering, South China University of Technology, Guangzhou 510640, China.
authors.forename: Pei
authors.initials: P
authors.lastname: Yu
authors.affiliation: National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
authors.forename: Xian-Bing
authors.initials: XB
authors.lastname: Xu
authors.affiliation: School of Food science and Engineering, South China University of Technology, Guangzhou 510640, China; Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, Guangzhou 510640, China. Electronic address: shujuanyu8@gmail.com.
authors.forename: Shu-Juan
authors.initials: SJ
authors.lastname: Yu
mesh_terms: D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D005947:Glucose; D017127:Glycation End Products, Advanced / Q000737:chemistry*; D008239:Lysine / Q000031:analogs & derivatives* / Q000737:chemistry; D015416:Maillard Reaction / Q000187:drug effects; D008965:Molasses / Q000032:analysis*; D011765:Pyruvaldehyde / Q000737:chemistry; D031786:Saccharum / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D017127:Glycation End Products, Advanced; C000612723:N(6)-carboxyethyllysine; C048496:N(6)-carboxymethyllysine; D011765:Pyruvaldehyde; D005947:Glucose; D008239:Lysine
keywords: N(ε)-(carboxyethyl)-lysine; N(ε)-(carboxymethyl)lysine; Reactive carbonyl species; Sugarcane molasses extract