title: How To Better Identify Patients That Do Not Benefit From Prophylactic ICD Therpy.
abstract: The implantable cardioverter defibrillator (ICD) has been demonstrated to improve survival by reducing sudden cardiac death (SCD) in patients with a low left ventricular ejection fraction (LVEF). Randomised trial data suggest that this mortality reduction is not constant among those implanted with a device, and has raised the significance of non-sudden cardiac death (non-SCD) as an important mode of death predicting limited benefit from ICD therapy. In this review article we explore the role of non-SCD and the risk prediction models that may aid identification of low LVEF patients unlikely to gain significant benefit from ICD therapy.
authors.affiliation: Department of Cardiology, King's College Hospital NHS Foundation Trust, London, UK.
authors.forename: Ian
authors.initials: I
authors.lastname: Mann
authors.affiliation: Department of Cardiology, King's College Hospital NHS Foundation Trust, London, UK.
authors.forename: Amit
authors.initials: A
authors.lastname: Kaura
authors.affiliation: Department of Cardiology, King's College Hospital NHS Foundation Trust, London, UK.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Scott