title: Nano-carbohydrates: Synthesis and application in genetics, biotechnology, and medicine.
abstract: Combining nanoparticles with carbohydrate has triggered an exponential growth of research activities for the design of novel functional bionanomaterials, nano-carbohydrates. Recent advances in versatile synthesis of glycosylated nanoparticles have paved the way towards diverse biomedical applications. The accessibility of a wide variety of these structured nanosystems, in terms of shape, size, and organization around stable nanoparticles, has readily contributed to their development and application in nanomedicine. Glycosylated gold nanoparticles, glycosylated quantum dots, fullerenes, single-wall nanotubes, and self-assembled glyconanoparticles using amphiphilic glycopolymers or glycodendrimers have received considerable attention for their application in powerful imaging, therapeutic, and biodiagnostic devices. Recently, nano-carbohydrates were used for different types of microarrays to detect proteins and nucleic acids.
authors.affiliation: Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Ashkezar, Yazd, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Jebali
authors.affiliation: Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Ashkezar, Yazd, Iran; Department of Biology, Ashkezar Branch, Islamic Azad University, Ashkezar, Iran.
authors.forename: Elham Khajeh
authors.initials: EK
authors.lastname: Nayeri
authors.affiliation: Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Ashkezar, Yazd, Iran; Department of Biology, Ashkezar Branch, Islamic Azad University, Ashkezar, Iran.
authors.forename: Sima
authors.initials: S
authors.lastname: Roohana
authors.affiliation: Department of Genetics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Shiva
authors.initials: S
authors.lastname: Aghaei
authors.affiliation: Department of Genetics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Maede
authors.initials: M
authors.lastname: Ghaffari
authors.affiliation: Department of Genetics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Karim
authors.initials: K
authors.lastname: Daliri
authors.affiliation: Department of Nanobiotechnology, Institute of Advanced Tech, Barcelona, Spain. Electronic address: garcia.fuente2016@gmail.com.
authors.forename: Garcia
authors.initials: G
authors.lastname: Fuente
mesh_terms: D000818:Animals; D001709:Biotechnology / Q000379:methods*; D002241:Carbohydrates / Q000138:chemical synthesis* / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D005823:Genetics; D006801:Humans; D050997:Nanomedicine / Q000379:methods*; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D002241:Carbohydrates
keywords: Application; Nano-carbohydrate; Nanoparticles; Synthesis