title: Introduction of Quinolines and Isoquinolines onto Nonactivated α-C-H Bond of Tertiary Amides through a Radical Pathway.
abstract: Treatment of quinolines and isoquinolines with benzoyl peroxide in tertiary amides, such as N,N-dimethylacetamide, N,N-dimethylpropionamide, and N-acetylpyrrolidine, etc., under irradiation with a Hg lamp in the temperature range of 35 °C to 40 °C gave C-C-bonded quinolines and isoquinolines bearing amide groups with high regioselectivity in good to moderate yields, respectively, under transition-metal-free conditions.
authors.affiliation: Graduate School of Science and ‡Molecular Chirality Research Center, Chiba University , Yayoi-cho 1-33, Inage-ku, Chiba 263-8522, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Okugawa
authors.affiliation: Graduate School of Science and ‡Molecular Chirality Research Center, Chiba University , Yayoi-cho 1-33, Inage-ku, Chiba 263-8522, Japan.
authors.forename: Katsuhiko
authors.identifier: 0000-0001-8443-3599
authors.initials: K
authors.lastname: Moriyama
authors.affiliation: Graduate School of Science and ‡Molecular Chirality Research Center, Chiba University , Yayoi-cho 1-33, Inage-ku, Chiba 263-8522, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Togo