title: Deprescribing: a new goal focused on the patient.
abstract: It is estimated that one-fifth of adult patients are treated with polypharmacy (five or more drugs) and the prevalence of this phenomenon in the elderly is even higher, ranging from 30% to 70%, even reaching 90% in residents of residential aged care facilities. Polypharmacy in the elderly increases the risk of adverse reactions, inappropriate prescriptions, drug interactions, number of hospitalizations, costs, and even death. In a recent systematic review, the authors proposed defining deprescribing as 'the process of withdrawal of inappropriate medication supervised by a health care professional with the goal of managing polypharmacy and improving outcomes'.
authors.affiliation: a Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia , Universidad Tecnológica de Pereira - Audifarma S.A. Pereira , Colombia , South America.
authors.forename: Jorge Enrique
authors.initials: JE
authors.lastname: Machado-Alba
authors.affiliation: a Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia , Universidad Tecnológica de Pereira - Audifarma S.A. Pereira , Colombia , South America.
authors.forename: Andrés
authors.initials: A
authors.lastname: Gaviria-Mendoza
authors.affiliation: a Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia , Universidad Tecnológica de Pereira - Audifarma S.A. Pereira , Colombia , South America.
authors.forename: Manuel Enrique
authors.initials: ME
authors.lastname: Machado-Duque
authors.affiliation: a Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia , Universidad Tecnológica de Pereira - Audifarma S.A. Pereira , Colombia , South America.
authors.forename: Laura
authors.initials: L
authors.lastname: Chica
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000069340:Deprescriptions; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology / Q000517:prevention & control*; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D057970:Inappropriate Prescribing / Q000517:prevention & control*; D019338:Polypharmacy; D012112:Residential Facilities / Q000706:statistics & numerical data
keywords: Deprescriptions; pharmacoepidemiology; pharmacovigilance; polypharmacy