title: Case of twin pregnancy complicated by idiopathic thrombocytopenic purpura treated with intravenous immunoglobulin: Review of the literature.
abstract: Idiopathic thrombocytopenic purpura (ITP) is an acquired thrombocytopenia without other clear cause of thrombocytopenia. It is not common in a singleton pregnancy and less common in twin pregnancy. We report a 33-year-old ITP pluripara whose first pregnancy was uneventful. She carried twin pregnancy, complicated by recurrent very low platelets, and gave birth to preterm twins. This patient received multiple courses of intravenous immunoglobulin (IVIG) and showed a significant platelet count improvement with IVIG therapy.
authors.affiliation: Department of Obstetrics and Gynecology, The Southern Division of Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
authors.forename: W X
authors.initials: WX
authors.lastname: Zhao
authors.affiliation: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Qingdao University Medical College, Qingdao, China.
authors.forename: X F
authors.initials: XF
authors.lastname: Yang
authors.affiliation: Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
authors.forename: J H
authors.initials: JH
authors.lastname: Lin
mesh_terms: D000328:Adult; D001792:Blood Platelets; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage* / Q000627:therapeutic use; D007231:Infant, Newborn; D010976:Platelet Count; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000188:drug therapy*; D011256:Pregnancy Outcome; D059285:Pregnancy, Twin; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous