title: A comparative study to assess the effect of oral alprazolam as premedication on vital parameters of patients during surgical removal of impacted mandibular third molars.
abstract: OBJECTIVE
  The aim of this study was to evaluate and monitor the changes in vital parameters of patients during surgical removal of impacted mandibular third molars.
  
  
  METHODS
  This was anin vivostudy conducted in Oral and Maxillofacial Surgery Department of Terna Dental College. Sixty patients were randomly selected. Thirty patients were given a preoperative single dose of oral tablet alprazolam 0.5 mg as premedication (test group), whereas the other thirty were treated without any premedication (control group).
  
  
  RESULTS
  It was found that the mean systolic blood pressure during surgical removal of impacted mandibular third molar was raised in the control group and exhibited minimal fluctuation in the test group.
  
  
  CONCLUSIONS
  The use of tablet alprazolam as premedication before surgical removal of impacted mandibular third molars resulted in stability of vital parameters, secondary to reduced patient anxiety.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Joshi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India.
authors.forename: Arsalan Shakil Ahmed
authors.initials: AS
authors.lastname: Ansari
authors.affiliation: Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India.
authors.forename: Sima
authors.initials: S
authors.lastname: Mazumdar
authors.affiliation: Department of Oral and Maxillofacial Surgery, Terna Dental College, Navi Mumbai, Maharashtra, India.
authors.forename: Sidra
authors.initials: S
authors.lastname: Ansari
keywords: Alprazolam; anxiety; impacted mandibular third molar