title: Spontaneous intracranial epidural hematoma during rivaroxaban treatment.
abstract: According to our research, this is the first case described in the literature of spontaneous intracranial epidural hematoma secondary to the use of Xareltor. Spontaneous intracranial epidural hematomas are rarely described in the literature. They are associated with infectious diseases of the skull, coagulation disorders, vascular malformations of the dura mater and metastasis to the skull. Long-term post-marketing monitoring and independent reports will probably detect the full spectrum of hemorrhagic complications of the use of rivaroxaban.
authors.affiliation: MD, Resident of the Neurosurgery Residency Program at Instituto de Neurologia de Curitiba (INC), Curitiba, PR, Brazil.
authors.forename: Leonardo Gilmone
authors.initials: LG
authors.lastname: Ruschel
authors.affiliation: MD, Resident of the Neurosurgery Residency Program at Instituto de Neurologia de Curitiba (INC), Curitiba, PR, Brazil.
authors.forename: Felipe Marques Monteiro do
authors.initials: FM
authors.lastname: Rego
authors.affiliation: PhD, Neurosurgeon, INC, Curitiba, PR, Brazil.
authors.forename: Jerônimo Buzetti
authors.initials: JB
authors.lastname: Milano
authors.affiliation: MD, Resident of the Neurosurgery Residency Program at Instituto de Neurologia de Curitiba (INC), Curitiba, PR, Brazil.
authors.forename: Gustavo Simiano
authors.initials: GS
authors.lastname: Jung
authors.affiliation: MD, Neurosurgeon, INC, Curitiba, PR, Brazil.
authors.forename: Luis Fernando
authors.initials: LF
authors.lastname: Silva
authors.affiliation: PhD, Head of the Neurosurgery Department, INC, Curitiba, PR, Brazil.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Ramina
mesh_terms: D000328:Adult; D065427:Factor Xa Inhibitors / Q000009:adverse effects*; D006407:Hematoma, Epidural, Cranial / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D012306:Risk; D000069552:Rivaroxaban / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D065427:Factor Xa Inhibitors; D000069552:Rivaroxaban