title: Operating the blues.
abstract: A 63-year-old man bearing most signs and symptoms (facial pigmentation, degenerative arthritis, and dark urine) pertinent to his known history of alkaptonuria underwent aortic valve replacement for critical aortic stenosis. Although rare, aortic stenosis is the most common cardiac manifestation of alkaptonuric ochronosis.
authors.affiliation: Department of Paediatric and Congenital Cardiac Surgery Onassis Cardiac Surgery Centre Athens Greece.
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Chatzis
authors.affiliation: Department of Paediatric and Congenital Cardiac Surgery Onassis Cardiac Surgery Centre Athens Greece.
authors.forename: Meletios A
authors.initials: MA
authors.lastname: Kanakis
authors.affiliation: Department of Anaesthesia Onassis Cardiac Surgery Centre Athens Greece.
authors.forename: Joanne
authors.initials: J
authors.lastname: Sofianidou
authors.affiliation: Department of Paediatric Cardiology Onassis Cardiac Surgery Centre Athens Greece.
authors.forename: Alexandros J
authors.initials: AJ
authors.lastname: Tsoutsinos
keywords: Alkaptonuria; aortic stenosis; ochronosis