title: Influence of cognitive function on quality of life in anorexia nervosa patients.
abstract: OBJECTIVE
  The purpose of this study was to elucidate determinants of quality of life (QOL) in anorexia nervosa (AN) patients.
  
  
  METHODS
  Twenty-one female patients with AN participated in the study. QOL was assessed with the 36-Item Short Form Health Survey (SF-36), and cognitive function was evaluated using the Wisconsin Card Sorting Test Keio version, the Rey Complex Figure Test, and the Social Cognition Screening Questionnaire. Clinical symptoms were evaluated with the Beck Depression Inventory-II, the State-Trait Anxiety Inventory-Form JYZ (STAI-JYZ), and the Maudsley Obsessive Compulsive Inventory.
  
  
  RESULTS
  The Difficulty Maintaining Set score of the Wisconsin Card Sorting Test Keio version was negatively correlated to the SF-36 Physical Component Summary. Scores of the Beck Depression Inventory-II and the STAI-JYZ State and Trait were negatively correlated to the SF-36 Mental Component Summary (MCS), and the Central Coherence Index 30-min Delayed Recall score of the Rey Complex Figure Test was positively correlated with the MCS. Stepwise regression analysis showed that the Difficulty Maintaining Set score was an independent predictor of the Physical Component Summary and scores for Central Coherence Index 30-min Delayed Recall and the STAI-JYZ Trait-predicted MCS.
  
  
  CONCLUSIONS
  These results suggest that not only trait anxiety but also poor central coherence and impaired ability to maintain new rule worsen AN patients' QOL.
authors.affiliation: Graduate School of Medical Sciences, Tokushima University, Tokushima, Japan.
authors.forename: Sayo
authors.identifier: http://orcid.org/0000-0001-7847-6381
authors.initials: S
authors.lastname: Hamatani
authors.affiliation: Department of Mental Health, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
authors.forename: Masahito
authors.initials: M
authors.lastname: Tomotake
authors.affiliation: Graduate School of Medical Sciences, Tokushima University, Tokushima, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Takeda
authors.affiliation: Department of Psychiatry, Tokushima University Hospital, Tokushima, Japan.
authors.forename: Naomi
authors.initials: N
authors.lastname: Kameoka
authors.affiliation: Department of Psychiatry, Tokushima University Hospital, Tokushima, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Kawabata
authors.affiliation: Department of Psychiatry, Tokushima University Hospital, Tokushima, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kubo
authors.affiliation: Department of Psychiatry, Tokushima University Hospital, Tokushima, Japan.
authors.forename: Yukio
authors.initials: Y
authors.lastname: Tada
authors.affiliation: Department of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Tomioka
authors.affiliation: Department of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Watanabe
authors.affiliation: Department of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Inoshita
authors.affiliation: Department of Psychiatry, Tokushima University Hospital, Tokushima, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Kinoshita
authors.affiliation: Department of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Ohta
authors.affiliation: Department of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Ohmori
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000150:complications / Q000523:psychology*; D001007:Anxiety / Q000150:complications / Q000523:psychology; D016022:Case-Control Studies; D003071:Cognition; D005260:Female; D006801:Humans; D009483:Neuropsychological Tests; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D055815:Young Adult
keywords: anorexia nervosa; central coherence; cognitive function; difficulty maintaining set; quality of life