title: Does saliva composition affect the formation of sialolithiasis?
abstract: OBJECTIVE
  Saliva composition may affect sialolithiasis formation; thus, this study compared the salivary inorganic composition of sialolithiasis patients with that of healthy controls, and determined whether salivary inorganic composition changes after sialolithiasis surgery.
  
  
  METHODS
  The study included 40 patients with sialolithiasis and 40 matched healthy controls. Patients were examined before and after sialolithiasis surgery; controls were examined once. Flow rate and the inorganic saliva composition in unstimulated whole saliva were assessed.
  
  
  RESULTS
  Patients' salivary flow prior to surgery was significantly lower compared to that of healthy controls, but equalised after surgery. Prior to surgery, patients' saliva exhibited higher concentrations of calcium, magnesium, phosphorous compared to that of healthy controls. The concentration of most ions remained high after sialolithiasis surgery.
  
  
  CONCLUSIONS
  Sialolithiasis patients had increased salivary concentrations of the ions that constitute the main inorganic phase of most sialoliths, and this may confer a risk for developing sialolithiasis.
authors.affiliation: Department of Otorhinolaryngology,Nordsjaellands University Hospital,Hillerod.
authors.forename: S A
authors.initials: SA
authors.lastname: Schrøder
authors.affiliation: Department of Otorhinolaryngology and Maxillofacial Surgery,Zealand University Hospital,Koege.
authors.forename: P
authors.initials: P
authors.lastname: Homøe
authors.affiliation: Department of Otorhinolaryngology,Aleris-Hamlet Hospital,Ringsted.
authors.forename: N
authors.initials: N
authors.lastname: Wagner
authors.affiliation: Department of Oral Medicine,Dental School of Copenhagen,University of Copenhagen,Denmark.
authors.forename: A
authors.initials: A
authors.lastname: Bardow
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002118:Calcium / Q000032:analysis; D016022:Case-Control Studies; D002712:Chlorides / Q000032:analysis; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000032:analysis; D011188:Potassium / Q000032:analysis; D011446:Prospective Studies; D012463:Saliva / Q000737:chemistry*; D015494:Salivary Gland Calculi / Q000453:epidemiology* / Q000601:surgery; D012964:Sodium / Q000032:analysis; D055815:Young Adult
chemical_list: D002712:Chlorides; D010758:Phosphorus; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium
keywords: Calcium; Calculi; Humans; Magnesium; Oral Health; Phosphates; Salivary Gland Calculi