title: Magnetic compression anastomosis for enteroenterostomy under peritonitis conditions in dogs.
abstract: The risk of complications and mortality are high after enteroenterostomy in severe peritonitic conditions. Magnetic compression anastomosis (MCA) is a sutureless technique of high efficacy and safety. The purpose of this study was to compare the efficacy of MCA for enteroenterostomy with stapled and hand-sewn techniques under peritonitic conditions.
  
  
  
  The peritonitic conditions were created by puncturing the colon with a circular blade in 27 mongrel dogs. Eight hours later, the peritoneal cavity was washed with warm, sterilized normal saline solution. The animals were then randomly divided into three groups and underwent colonic anastomosis with MCA, stapled, or hand-sewn techniques, respectively. Animals were euthanized at 1, 2, and 4 w after the operation; anastomoses were compared on the basis of gross appearance and histology.
  
  
  
  All magnetic devices formed patent anastomoses without a leak. However, one stapled anastomosis and three hand-sewn anastomoses resulted in leaks. The anastomosis time was significantly less in the MCA group than that of the other two groups (P < 0.05). All magnetic devices were expelled naturally. The pathologic observation showed that the healing of anastomoses for MCA was smoother than that of the other two groups.
  
  
  
  MCA is a feasible, safe, and effective alternative for enteroenterostomy under peritonitic conditions in the canine model.
authors.affiliation: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.
authors.forename: Hongke
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, P. R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Tan
authors.affiliation: Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, P. R. China.
authors.forename: Chao
authors.initials: C
authors.lastname: Fan
authors.affiliation: Department of Clinical Medicine, Xi'an Jiaotong University Health Science Center, Xi'an, P. R. China.
authors.forename: Jingwei
authors.initials: J
authors.lastname: Du
authors.affiliation: Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, P. R. China.
authors.forename: Jiangbin
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, P. R. China.
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.affiliation: Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lv
authors.affiliation: Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, P. R. China. Electronic address: dxlin0705@163.com.
authors.forename: Xilin
authors.initials: X
authors.lastname: Du
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods*; D000818:Animals; D015415:Biomarkers / Q000097:blood; D003106:Colon / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D005240:Feasibility Studies; D007239:Infections / Q000097:blood; D059346:Magnets; D011897:Random Allocation
chemical_list: D015415:Biomarkers
keywords: Enteroenterostomy; Hand-sewn anastomosis; Magnetic compression anastomosis; Peritonitis; Stapled anastomosis