title: Long-term efficacy and safety of tension free vaginal tape in a historic cohort of 463 women with stress urinary incontinence.
abstract: OBJECTIVE
  We report retrospective data on the long-term safety and efficacy of the retropubic midurethral sling (MUS) in a large series of women with stress urinary incontinence.
  
  
  METHODS
  In all, 517 patients were treated during the period January 2005 to June 2012 at a single centre in France. The Urinary Symptoms Profile score was used to identify women who were subjectively cured or improved or in whom treatment had failed. The rates of peroperative, and early (<30 days) and late postoperative complications were recorded.
  
  
  RESULTS
  A total of 463 patients were evaluable at a mean (±SD) follow-up of 71 ± 23 months. At the last follow-up, 344 patients (74.3 %) demonstrated subjective cure, 55 (11.9 %) were improved and 64 (13.8 %) had treatment failure. Bladder perforations occurred in 33 patients (7.1 %); however, this had no effect on cure rate. In the early postoperative period, temporary intermittent self-catheterization was required in 10 patients (2.2 %) due to voiding difficulties. The most frequent long-term postoperative complication was de novo urge incontinence that was reported by 59 patients (12.7 %); seven patients (1.5 %) needed tape excision due to voiding difficulties and six (1.3 %) needed tape removal due to erosion or chronic pain.
  
  
  CONCLUSIONS
  The retropubic MUS was shown to be durable at a mean follow-up of 71 ± 23 months, with a high success/improvement rate and no serious long-term tape-induced adverse effects.
authors.affiliation: Urology and Andrology Department, University Hospital of Nîmes, CHU Caremeau, Place du Professeur Robert Debré, 30029, Nîmes, Cedex 9, France. armand.chevrot@hotmail.fr.
authors.forename: Armand
authors.initials: A
authors.lastname: Chevrot
authors.affiliation: Urology and Andrology Department, University Hospital of Nîmes, CHU Caremeau, Place du Professeur Robert Debré, 30029, Nîmes, Cedex 9, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Droupy
authors.affiliation: Urology and Andrology Department, University Hospital of Nîmes, CHU Caremeau, Place du Professeur Robert Debré, 30029, Nîmes, Cedex 9, France.
authors.forename: Gregoire
authors.initials: G
authors.lastname: Coffin
authors.affiliation: Urology and Andrology Department, University Hospital of Nîmes, CHU Caremeau, Place du Professeur Robert Debré, 30029, Nîmes, Cedex 9, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Soustelle
authors.affiliation: Urology and Andrology Department, University Hospital of Nîmes, CHU Caremeau, Place du Professeur Robert Debré, 30029, Nîmes, Cedex 9, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Boukaram
authors.affiliation: Department of Obstetrics and Gynaecology, University Hospital, Nîmes, France.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Fatton
authors.affiliation: Department of Obstetrics and Gynaecology, University Hospital, Nîmes, France.
authors.forename: Renaud
authors.initials: R
authors.lastname: de Tayrac
authors.affiliation: Urology and Andrology Department, University Hospital of Nîmes, CHU Caremeau, Place du Professeur Robert Debré, 30029, Nîmes, Cedex 9, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Wagner
authors.affiliation: Urology and Andrology Department, University Hospital of Nîmes, CHU Caremeau, Place du Professeur Robert Debré, 30029, Nîmes, Cedex 9, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Costa
mesh_terms: D000368:Aged; D053159:Dysuria / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D005602:France; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D053825:Suburethral Slings / Q000009:adverse effects*; D013995:Time; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D053202:Urinary Incontinence, Urge / Q000209:etiology*
keywords: Longterm adverse effect; Suburethral slings; Treatment outcome; Urinary incontinence, stress