title: Computational chemistry at Janssen.
abstract: Computer-aided drug discovery activities at Janssen are carried out by scientists in the Computational Chemistry group of the Discovery Sciences organization. This perspective gives an overview of the organizational and operational structure, the science, internal and external collaborations, and the impact of the group on Drug Discovery at Janssen.
authors.affiliation: Discovery Sciences, Janssen Research and Development, Beerse, Belgium. hvvlijme@its.jnj.com.
authors.forename: Herman
authors.initials: H
authors.lastname: van Vlijmen
authors.affiliation: Discovery Sciences, Janssen Research and Development, Spring House, PA, USA.
authors.forename: Renee L
authors.initials: RL
authors.lastname: Desjarlais
authors.affiliation: Discovery Sciences, Janssen Research and Development, La Jolla, CA, USA.
authors.forename: Tara
authors.initials: T
authors.lastname: Mirzadegan
mesh_terms: D002626:Chemistry, Pharmaceutical; D019295:Computational Biology; D017076:Computer-Aided Design; D015195:Drug Design; D055808:Drug Discovery / Q000379:methods*; D004345:Drug Industry / Q000379:methods*; D008958:Models, Molecular; D012106:Research; D012984:Software
keywords: Computational chemistry; Computer aided drug design; Drug discovery