title: To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis.
abstract: The term functionalized isocyanides refers to all those isocyanides in which a neighbouring functional group can finely tune the reactivity of the isocyano group or can be exploited in post-functionalization processes. In this manuscript, we have reviewed all the isocyanides in which the pendant functional group causes either deviation from or reinforces the normal reactivity of the isocyano group and categorized them to highlight their common features and differences. An analysis of their synthetic potential and the possible unexplored directions for future research studies is also addressed.
authors.affiliation: Dipartimento di Farmacia, Università degli Studi di Napoli "Federico II", via D. Montesano 49, 80131 Napoli, Italy.
authors.forename: Mariateresa
authors.initials: M
authors.lastname: Giustiniano
authors.affiliation: Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Genova, via Dodecaneso 31, 16143 Genova, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Basso
authors.affiliation: Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale "A. Avogadro", largo Donegani 2, 28100 Novara, Italy. giancesare.tron@uniupo.it.
authors.forename: Valentina
authors.initials: V
authors.lastname: Mercalli
authors.affiliation: Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale "A. Avogadro", largo Donegani 2, 28100 Novara, Italy. giancesare.tron@uniupo.it.
authors.forename: Alberto
authors.initials: A
authors.lastname: Massarotti
authors.affiliation: Dipartimento di Farmacia, Università degli Studi di Napoli "Federico II", via D. Montesano 49, 80131 Napoli, Italy.
authors.forename: Ettore
authors.initials: E
authors.lastname: Novellino
authors.affiliation: Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale "A. Avogadro", largo Donegani 2, 28100 Novara, Italy. giancesare.tron@uniupo.it.
authors.forename: Gian Cesare
authors.initials: GC
authors.lastname: Tron
authors.affiliation: Laboratory of Synthesis and Natural Products, Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, EPFL-SB-ISIC-LSPN, BCH 5304, 1015 Lausanne, Switzerland. jieping.zhu@epfl.ch.
authors.forename: Jieping
authors.initials: J
authors.lastname: Zhu