title: Pediatric melanoma.
abstract: Childhood melanoma is a rare pediatric malignancy, with fewer than 500 new diagnoses annually. The incidence is increasing, particularly in the adolescent population. This review highlights the epidemiology, clinical presentation, and histopathologic challenges of pediatric melanoma. Surgical resection remains the cornerstone for localized and regionally advanced disease. Adjuvant therapies, including current options and potential novel therapeutics for this unique population will be discussed.
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
authors.forename: Elisabeth T
authors.initials: ET
authors.lastname: Tracy
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, Nationwide Children׳s Hospital, The Ohio State University College of Medicine, Nationwide Children׳s Dr, FB Suite 6B.1, Columbus, Ohio 43205. Electronic address: Jennifer.aldrink@nationwidechildrens.org.
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: Aldrink
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002648:Child; D062109:Dermatologic Surgical Procedures; D006801:Humans; D008197:Lymph Node Excision; D008545:Melanoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D009367:Neoplasm Staging; D010372:Pediatrics; D012878:Skin Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D014481:United States / Q000453:epidemiology
chemical_list: D000970:Antineoplastic Agents
keywords: Melanoma; Pediatric