title: Termination of pregnancy due to renal tract abnormalities: survey of 97 fetuses from a single medical center.
abstract: OBJECTIVE
  The article aimed to assess the spectrum of fetal renal tract abnormalities as a major finding leading to termination of pregnancy (TOP).
  
  
  METHODS
  The study population included all pregnant women with singleton pregnancy who underwent TOP in our institute because of fetal renal tract indications between 1998 and 2015. We specifically excluded TOPs performed because of multiple pregnancies, multisystem defects, abnormal karyotype and chromosomal or genetic defect not related to renal tract abnormalities. The patients were stratified into late TOP (≥24 weeks' gestation) and early TOP (<24 weeks' gestation).
  
  
  RESULTS
  There were 97 (3.5%) cases of TOP because of fetal renal abnormalities and are the subjects of this study. Of these cases, 19 (19.6%) were at ≥24 weeks' gestation. Renal cystic disease was the leading indication for late TOP compared with early TOP group (31.8% vs 21.8%, respectively, p = 0.001). Routine prenatal care raised suspicion of abnormalities in 11 (50.9%) cases, and diagnosis was established by additional tests. Abnormal findings were either missed in one (5.3%) case or developed later in two (10.5%) cases. No routine prenatal screening was performed in the remaining five (26.3%) cases.
  
  
  CONCLUSIONS
  We found a different distribution for fetal renal tract abnormalities leading to late versus early TOP. As many of renal tract malformations could have been diagnosed earlier (~32%), timely scanning may reduce the need for late TOPs in some cases. © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Yaakov
authors.initials: Y
authors.lastname: Melcer
authors.affiliation: Anesthesia, Pain and Intensive Care Division, Tel Aviv Sourasky Medical Center, Affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Gaby
authors.initials: G
authors.lastname: Kaplan
authors.affiliation: Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Ido
authors.initials: I
authors.lastname: Ben-Ami
authors.affiliation: Pediatric Nephrology Service, Assaf Harofeh Medical Center, Affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Hilla
authors.initials: H
authors.lastname: Bahat
authors.affiliation: Pediatric Urology Service, Assaf Harofeh Medical Center, Affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Amos
authors.initials: A
authors.lastname: Neheman
authors.affiliation: Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Narine
authors.initials: N
authors.lastname: Galoyan
authors.affiliation: Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Ron
authors.initials: R
authors.lastname: Maymon
mesh_terms: D000025:Abortion, Eugenic / Q000706:statistics & numerical data*; D000028:Abortion, Induced / Q000706:statistics & numerical data; D000328:Adult; D005260:Female; D005865:Gestational Age; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D011247:Pregnancy; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal; D014564:Urogenital Abnormalities / Q000175:diagnosis* / Q000453:epidemiology*