title: Delayed tongue necrosis simultaneous with bilateral osteoradionecrosis of the jaw secondary to head and neck irradiation.
abstract: We present a rare case of massive tongue necrosis occurring simultaneously with bilateral osteoradionecrosis (ORN) of the jaw in a patient with a history of treatment, including surgery and postoperative radiotherapy, for a retromolar trigone carcinoma 8 years earlier. There is a distinct possibility that the extractions and administration of local anesthesia with a vasoconstrictor contributed to the onset of ORN; together, these events may have influenced the blood supply to the tongue. A glossectomy was performed after hyperbaric oxygen therapy. One month after the surgical procedure, the patient responded satisfactorily to the treatment, showing significant improvement in speech and oral food intake, as well as significant decrease in lingual pain. Although the simultaneous occurrence of these oral complications is rare, the practitioner must be aware of the factors that instigate ORN and compromise vasculature as well as the clinical signs of tongue necrosis. Additionally, the possibility of tongue necrosis secondary to irradiation of the head and neck should be taken into consideration when an irradiated patient undergoes tooth extractions under local anesthesia with agents containing epinephrine.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Universidade do Sagrado Coração, Bauru, São Paulo, Brazil; Department of Oral Surgery, Hospital Santa Catarina, São Paulo, Brazil.
authors.forename: Marcos Martins
authors.initials: MM
authors.lastname: Curi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Universidade do Sagrado Coração, Bauru, São Paulo, Brazil; Department of Oral Surgery, Hospital Santa Catarina, São Paulo, Brazil. Electronic address: Cardoso_lopes@yahoo.com.br.
authors.forename: Camila Lopes
authors.initials: CL
authors.lastname: Cardoso
authors.affiliation: Department of Oral Surgery, Universidade Sagrado Coração, Bauru, São Paulo, Brazil.
authors.forename: Anthony Froy Condezo
authors.initials: AFC
authors.lastname: Benites
authors.affiliation: Department of Oral Surgery, Universidade Sagrado Coração, Bauru, São Paulo, Brazil.
authors.forename: Patrícia Martins
authors.initials: PM
authors.lastname: Bueno
mesh_terms: D016371:Cranial Irradiation / Q000009:adverse effects*; D006258:Head and Neck Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D008875:Middle Aged; D010025:Osteoradionecrosis / Q000209:etiology* / Q000601:surgery; D014059:Tongue / Q000528:radiation effects*; D014060:Tongue Diseases / Q000209:etiology* / Q000601:surgery