title: A new exploration of licorice metabolome.
abstract: The roots and rhizomes of licorice plants (genus Glycyrrhiza L.) are commercially employed, after processing, in confectionery production or as sweetening and flavouring agents in the food, tobacco and beer industries. G. glabra, G. inflata and G. uralensis are the most significant licorice species, often indistinctly used for different productions. Licorice properties are directly related to its chemical composition, which determines the commercial values and the quality of the derived products. In order to better understand the characteristics and properties of each species, a chemical characterization of three species of licorice (G. glabra, G. inflata, G. uralensis) is proposed, through an untargeted metabolomic approach and using high-resolution mass spectrometry. The statistical analysis reveals new possible markers for the analyzed species, and provides a reliable identification of a high number of metabolites, contributing to the characterization of Glycyrrhiza metabolome.
authors.affiliation: Department of Environmental Sciences, Informatics and Statistics, University of Venice, Ca' Foscari, Via Torino, 155, 30172 Venezia Mestre (VE), Italy. Electronic address: giovanni.rizzato@unive.it.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Rizzato
authors.affiliation: Department of Environmental Sciences, Informatics and Statistics, University of Venice, Ca' Foscari, Via Torino, 155, 30172 Venezia Mestre (VE), Italy. Electronic address: elisa.scalabrin@unive.it.
authors.forename: Elisa
authors.initials: E
authors.lastname: Scalabrin
authors.affiliation: Department of Environmental Sciences, Informatics and Statistics, University of Venice, Ca' Foscari, Via Torino, 155, 30172 Venezia Mestre (VE), Italy. Electronic address: marta.radaelli@unive.it.
authors.forename: Marta
authors.initials: M
authors.lastname: Radaelli
authors.affiliation: Department of Environmental Sciences, Informatics and Statistics, University of Venice, Ca' Foscari, Via Torino, 155, 30172 Venezia Mestre (VE), Italy. Electronic address: capoda@unive.it.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Capodaglio
authors.affiliation: S.C.S.O.P., Via Bornò 5, 23896 Sirtori (LC), Italy. Electronic address: orestepiccolo@tin.it.
authors.forename: Oreste
authors.initials: O
authors.lastname: Piccolo
mesh_terms: D006035:Glycyrrhiza / Q000378:metabolism*; D013058:Mass Spectrometry; D055442:Metabolome; D018517:Plant Roots / Q000378:metabolism*
keywords: Glabridin (PubChem CID: 124052); Glycyrrhizin (PubChem CID: 14982); Guangsangon F (PubChem CID: 12137388); HPLC-HRMS; Kanzonol Y (PubChem CID: 10001604); Licochalcone A (PubChem CID: 5318998); Licochalcone D (PubChem CID: 10473311); Licorice; Metabolomics; Mulberrofuran K (PubChem CID: 14334316); Quercetin (PubChem CID: 5280343)