title: RECOPE: How to succeed in bringing ideas from academia to market without compromising ingenuity.
abstract: Translation of biomedical technology originated in academia to the market is hindered by lack of consideration of market needs and commercialization pathways that leads academic research away from the market, leaving the public without long-awaited cures. Here we describe Reverse Conceptual Product Engineering (RECOPE), an approach applied in academic setting early in the course of the research project to facilitate biomedical research translation from bench to bedside. By using expertise of diverse set of biomedical professionals and trainees to solve a problem, RECOPE helps to make research goals more relevant to the society needs and translatable in a long-term perspective. Through the use of RECOPE one can critically reassess research design and translational potential and identify new market opportunities. RECOPE also provides for considerable educational opportunities to pre- and post-doctoral trainees. Adoption of RECOPE as a basic to for research design education will have a noticeable impact on academic research.
authors.affiliation: Center for Drug Delivery and Nanomedicine, University of Nebraska Medical Center, Omaha, NE, United States; RTI International, Durham, NC, United States.
authors.forename: Zagit
authors.initials: Z
authors.lastname: Gaymalov
authors.affiliation: Center for Drug Delivery and Nanomedicine, University of Nebraska Medical Center, Omaha, NE, United States; Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: kabanov@email.unc.edu.
authors.forename: Alexander
authors.initials: A
authors.lastname: Kabanov
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D062069:Inventions; D011994:Recombinant Proteins / Q000627:therapeutic use; D012107:Research Design; D020521:Stroke / Q000188:drug therapy; D018581:Technology Transfer; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D057170:Translational Research, Biomedical / Q000193:education / Q000379:methods*
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator; C077412:unglycosylated rt-PA
keywords: Academic innovation; Commercialization; Stroke; Translational research