title: Determination of oxathiapiprolin concentration and dissipation in grapes and soil by ultrahigh-performance liquid chromatography-tandem mass spectrometry.
abstract: BACKGROUND
  The residue concentrations and dissipation rate of a new oxathiapiprolin fungicide in grapes and soil were investigated to provide an evaluation for the safe use of oxathiapiprolin in grapes. Pesticide residue was extracted by acetonitrile, then purified by solid-phase extraction with an Envi-Carb cartridge and determined by ultrahigh-performance liquid chromatography-tandem mass spectrometry.
  
  
  RESULTS
  The fortified recoveries ranged from 85.2% to 99.0%, with relative standard deviations of 1.7-4.5%. The limit of quantitation for oxathiapiprolin in grapes and soil was 0.002 mg kg-1. The mean initial deposits of oxathiapiprolin in grapes were 0.345-0.565 mg kg-1, with half-lives of 8.6-9.2 days. The mean initial deposits of oxathiapiprolin in soil were 0.078-0.273 mg kg-1, with half-lives of 7.6-12.0 days. The oxathiapiprolin residue in grapes and soil was 0.002-0.022 mg kg-1and 0.002-0.123 mg kg-1when sampling 14 days after application, respectively.
  
  
  CONCLUSIONS
  The residue in the grapes was less than 0.01 mg kg-1when sampling 28 days after application, which suggested that the application rate of 20 mg a.i. kg-1for this fungicide should be used to ensure that treated grapes can be considered safe for humans to consume when sampling 28 days after the final application. © 2016 Society of Chemical Industry.
authors.affiliation: Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Science, Beijing, China.
authors.forename: Pingzhong
authors.initials: P
authors.lastname: Yu
authors.affiliation: Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Science, Beijing, China.
authors.forename: Chunhong
authors.initials: C
authors.lastname: Jia
authors.affiliation: Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Science, Beijing, China.
authors.forename: Ercheng
authors.initials: E
authors.lastname: Zhao
authors.affiliation: Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Science, Beijing, China.
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.affiliation: Beijing Vegetable Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
authors.forename: Hongju
authors.initials: H
authors.lastname: He
authors.affiliation: Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Science, Beijing, China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Jing
authors.affiliation: Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Science, Beijing, China.
authors.forename: Min
authors.initials: M
authors.lastname: He
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004350:Drug Residues / Q000737:chemistry*; D005506:Food Contamination / Q000032:analysis; D005659:Fungicides, Industrial / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000032:analysis*; D011720:Pyrazoles / Q000032:analysis*; D012987:Soil / Q000737:chemistry; D012989:Soil Pollutants / Q000737:chemistry*; D053719:Tandem Mass Spectrometry; D027843:Vitis / Q000737:chemistry*
chemical_list: D005659:Fungicides, Industrial; D006845:Hydrocarbons, Fluorinated; D011720:Pyrazoles; D012987:Soil; D012989:Soil Pollutants; C000592431:oxathiapiprolin
keywords: UPLC-MS/MS; dissipation; grape; oxathiapiprolin; pesticide residue