title: UroLift in Place of Fiducial Markers for Patients With Benign Prostatic Hyperplasia Undergoing External Beam Radiation Therapy.
abstract: OBJECTIVE
  To investigate if using a novel treatment for obstructive benign prostatic hyperplasia (UroLift) to relive lower urinary tract symptoms (LUTS) prior to external beam radiotherapy (EBRT) could also supplant the use of fiducial markers obviating the need for a second transrectal procedure while facilitating symptom-free voiding during and after EBRT a series of patients are reported on.
  
  
  METHODS
  The medical records of 7 consecutive patients who underwent placement of UroLift for simultaneous treatment of obstructive LUTS due to benign prostatic hyperplasia and targeting of EBRT for treatment of prostate cancer between September and December of 2015 were reviewed.
  
  
  RESULTS
  The UroLift clips were sufficiently radiopaque to make targeting possible for EBRT. All patients were able to complete a full course of radiotherapy without placement of fiducial markers. No patient experienced complications that could be attributed to the UroLift implants or procedure during their course of radiotherapy. None of the patients required additional alpha-blockers during radiation therapy.
  
  
  CONCLUSIONS
  The UroLift system can serve as fiducial markers in patients undergoing EBRT. Although the current clip utilized in the UroLift system is generally radiopaque, it does not project well on the sagittal plane and would be significantly enhanced if a more strongly opaque substance was incorporated. It remains to be proven if the UroLift system can significantly reduce the symptoms of LUTS during and post EBRT.
authors.affiliation: Department of Urology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY.
authors.forename: Aryeh
authors.initials: A
authors.lastname: Keehn
authors.affiliation: Department of Urology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY.
authors.forename: Ethan
authors.initials: E
authors.lastname: Fram
authors.affiliation: Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY.
authors.forename: Madhur
authors.initials: M
authors.lastname: Garg
authors.affiliation: Department of Urology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY. Electronic address: pmaria@montefiore.org.
authors.forename: Pedro
authors.initials: P
authors.lastname: Maria
mesh_terms: D000368:Aged; D057918:Fiducial Markers; D005500:Follow-Up Studies; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology / Q000532:radiotherapy*; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000150:complications / Q000532:radiotherapy*; D011471:Prostatic Neoplasms / Q000150:complications / Q000532:radiotherapy*; D019736:Prostheses and Implants / Q000009:adverse effects; D016896:Treatment Outcome; D014965:X-Rays