title: Spontaneous rupture of hepatic metastasis from a thymoma: A case report.
abstract: Bleeding resulting from spontaneous rupture of the liver is an infrequent but potentially life threatening complication that may be associated with an underlying liver disease. A hepatocellular carcinoma or hepatic adenoma is frequently reported is such cases. However, hemoperitoneum resulting from a hepatic metastatic thymoma is extremely rare. Here, we present a case of a 62-year-old man with hypovolemic shock induced by ruptured hepatic metastasis from a thymoma. At the first hospital admission, the patient had a 45-mm anterior mediastinal mass that was eventually diagnosed as a type A thymoma. The mass was excised, and the patient was disease-free for 6 years. He experienced sudden-onset right upper quadrant pain and was again admitted to our hospital. We noted large hemoperitoneum with a 10-cm encapsulated mass in S5/8 and a 2.3-cm nodular lesion in the right upper quadrant of the abdomen. He was diagnosed with hepatic metastasis from the thymoma, and he underwent chemotherapy and surgical excision.
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Ho Jae
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Yong Eun
authors.initials: YE
authors.lastname: Park
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Min Seo
authors.initials: MS
authors.lastname: Ki
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Se Ju
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Seung Hun
authors.initials: SH
authors.lastname: Beom
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Dai Hoon
authors.initials: DH
authors.lastname: Han
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Young Nyun
authors.initials: YN
authors.lastname: Park
authors.affiliation: Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Jun Yong Park, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Jun Yong
authors.initials: JY
authors.lastname: Park
mesh_terms: D015901:Angiography, Digital Subtraction; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D004621:Embolization, Therapeutic; D006465:Hemoperitoneum / Q000209:etiology; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000556:secondary* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012422:Rupture, Spontaneous; D012769:Shock / Q000209:etiology; D013934:Thymectomy; D013945:Thymoma / Q000150:complications / Q000556:secondary* / Q000628:therapy; D013953:Thymus Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Hemoperitoneum; Hepatic metastasis; Spontaneous rupture; Thymoma; Transarterial chemoembolization