title: Emergence of sequence type 11 Klebsiella pneumoniae coproducing NDM-1 and VIM-1 metallo-β-lactamases in a Greek hospital.
abstract: Sequence type 11 Klebsiella pneumoniae, coproducing NDM-1 and VIM-1 metallo-β-lactamases, were isolated in a Greek hospital. blaNDM-1was part of a Tn125 derivative, located on an ~90-kb plasmid similar to the NDM-1-encoding plasmid pB-3002cz. blaVIM-1was located in an In-e541-like integron, carried on a multireplicon (IncA/C and IncR) plasmid of ~180kb.
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece; Biomedical Center, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic.
authors.forename: C C
authors.initials: CC
authors.lastname: Papagiannitsis
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece.
authors.forename: E
authors.initials: E
authors.lastname: Malli
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece.
authors.forename: Z
authors.initials: Z
authors.lastname: Florou
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Sarrou
authors.affiliation: Biomedical Center, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Hrabak
authors.affiliation: Department of Critical Care, Medical School, University of Thessaly, Larissa, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Mantzarlis
authors.affiliation: Department of Critical Care, Medical School, University of Thessaly, Larissa, Greece.
authors.forename: E
authors.initials: E
authors.lastname: Zakynthinos
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece. Electronic address: petinaki@med.uth.gr.
authors.forename: E
authors.initials: E
authors.lastname: Petinaki
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D015780:Carbapenems / Q000494:pharmacology*; D006115:Greece; D006761:Hospitals; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy* / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D015780:Carbapenems; C417264:VIM-1 metallo-beta-lactamase; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1; C063912:carbapenemase
keywords: Carbapenemases; Colonization; Enterobacteriaceae; NDM-1; VIM-1