title: Respiratuvar depression after accidental nasal ingestion of brimonidine eye drops in infant.
abstract: OBJECTIVE
  Brimonidine tartrate is an alpha-2 agonist used for glaucoma treatment. It can lead to serious poisoning symptoms when misused by children.
  
  
  METHODS
  In this case report, 3 months-old male patient with severe central nervous system depression and respiratory arrest as a result of accidentally nasal instillation of 1 cc brimonidine tartrate that benefited from mechanic ventilation and naloxone treatment was presented.
  
  
  CONCLUSIONS
  This case report suggested, that misuse of nasal brimonidine eye drop could result in serious respiratory distress and central nervous system depression. Mechanical ventilation and naloxone administration can be useful for these patients.
authors.affiliation: Dicle University Medical School, Department of Pediatrics, Diyarbakir, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Gunes
authors.affiliation: Dicle University Medical School, Department of Pediatrics, Diyarbakir, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Balik
authors.affiliation: Dicle University Medical School, Department of Pediatrics, Diyarbakir, Turkey.
authors.forename: Servet
authors.initials: S
authors.lastname: Yel
authors.affiliation: Pamukkale University Medical School, Department of Pediatrics, Denizli, Turkey.
authors.forename: Halil
authors.initials: H
authors.lastname: Kocamaz
authors.affiliation: Gaziantep University, Medical School Department of Pediatric Critical Care, Gaziantep, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bosnak
keywords: Brimonidine intoxication; Children; Nasal ingestion