title: Mature CD8+T-cell clonal expansion in the oral cavity and digestive tract: a severe lymphoid malignancy that mimics Crohn's disease.
abstract: In patients with atypical Crohn's disease features, including severe oral ulcerations and resistance to standard treatment, the possibility of a mature clonal CD8+T-cell lymphoproliferative disorder should be investigated. Clinicians should be aware of this differential diagnosis because CD8+T-cell lymphoma prognosis can be remarkably favorable upon oral treatment with cyclophosphamide.
authors.affiliation: Service d'Hématologie Hôpital Saint-Antoine, AP-HP Paris France; Centre de Référence des Microangiopathies Thrombotiques Hôpital Saint-Antoine, AP-HP Paris France; UPMC Univ Paris 06 Paris France; Inserm U1170 Institut Gustave Roussy Villejuif France.
authors.forename: Paul
authors.initials: P
authors.lastname: Coppo
authors.affiliation: Service d'Anatomopathologie Hôpital Saint-Antoine, AP-HP Paris France.
authors.forename: Bettina
authors.initials: B
authors.lastname: Fabiani
authors.affiliation: Laboratoire d'Hématologie et d'Immunologie Hôpital Saint-Antoine, AP-HP Paris France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Marzac
authors.affiliation: UPMC Univ Paris 06ParisFrance; Service de Gastro-EntérologieHôpital Saint-Antoine, AP-HPParisFrance.
authors.forename: Harry
authors.initials: H
authors.lastname: Sokol
keywords: Crohn's disease; cyclophosphamide; digestive lymphoma; peripheral T‐cell lymphoma