title: Hepatitis E Virus Infection after Platelet Transfusion in an Immunocompetent Trauma Patient.
abstract: Hepatitis E virus (HEV) infection causes acute liver disease, but severe infections are rare in immunocompetent patients. We describe a case of HEV infection in a previously healthy male trauma patient in France who received massive transfusions. Genotyping confirmed HEV in a transfused platelet pool and the donor.
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Loyrion
authors.forename: Thibaut
authors.initials: T
authors.lastname: Trouve-Buisson
authors.forename: Patricia
authors.initials: P
authors.lastname: Pouzol
authors.forename: Sylvie
authors.initials: S
authors.lastname: Larrat
authors.forename: Thomas
authors.initials: T
authors.lastname: Decaens
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Payen
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D000998:Antiviral Agents / Q000627:therapeutic use*; D001782:Blood Donors / Q000941:ethics; D001792:Blood Platelets / Q000821:virology*; D001803:Blood Transfusion / Q000379:methods; D041881:Cholecystitis, Acute / Q000503:physiopathology / Q000601:surgery / Q000628:therapy; D016751:Hepatitis E / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D016752:Hepatitis E virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D008297:Male; D017713:Platelet Transfusion / Q000009:adverse effects*; D012128:Respiratory Distress Syndrome / Q000503:physiopathology / Q000628:therapy; D012254:Ribavirin / Q000627:therapeutic use*; D012272:Ribs / Q000293:injuries; D012772:Shock, Septic / Q000503:physiopathology / Q000628:therapy; D013154:Spleen / Q000293:injuries; D013156:Splenectomy; D013161:Splenic Rupture / Q000601:surgery
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents; D012254:Ribavirin
keywords: HEV; blood transfusion; cholestasis; contaminated blood products; hepatitis E virus; immunocompetent; injury; jaundice; opportunistic infection; platelet transfusion; transfusion; trauma; viruses