title: Effects of Co-solvents on Reactions Run under Micellar Catalysis Conditions.
abstract: The impact of varying percentages of an organic solvent added to reactions run in aqueous nanomicelles as the reaction medium has been investigated. Issues such as rates of reaction, percent conversion, and yield, as well as various practical aspects (e.g., effect on stirring, etc.), are discussed, leading to an operationally simple method for the general improvement of potentially problematic systems across a broad range of reaction types, in particular for reactions run at scale.
authors.affiliation: Department of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Gabriel
authors.affiliation: Department of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Lee
authors.affiliation: Chimie Paris Tech , Paris, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Bigorne
authors.affiliation: Department of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
authors.forename: Piyatida
authors.initials: P
authors.lastname: Klumphu
authors.affiliation: Novartis Pharma AG , Basel, Switzerland.
authors.forename: Michael
authors.initials: M
authors.lastname: Parmentier
authors.affiliation: Novartis Pharma AG , Basel, Switzerland.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Gallou
authors.affiliation: Department of Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
authors.forename: Bruce H
authors.identifier: 0000-0001-9116-7049
authors.initials: BH
authors.lastname: Lipshutz