title: Incidence of Hospitalized Stroke in the Czech Republic: The National Registry of Hospitalized Patients.
abstract: BACKGROUND
  Contemporary stroke incidence data are not available in some countries and regions, including in Eastern Europe. Based on previous validation of the accuracy of the National Registry of Hospitalized Patients (NRHOSP), we report the incidence of hospitalized stroke in the Czech Republic (CR) using the NRHOSP.
  
  
  METHODS
  The results of the prior validation study assessing the accuracy of coding of stroke diagnoses in the NRHOSP were applied, and we calculated (1) the overall incidence of hospitalized stroke and (2) the incidence rates of hospitalized stroke for the three main stroke types: cerebral infarction (International Classification of Diseases Tenth Revision, CI I63), subarachnoid hemorrhage (SAH I60), and intracerebral hemorrhage (ICH I61). We calculated the average annual age- and sex-standardized incidence.
  
  
  RESULTS
  The overall incidence of hospitalized stroke was 241 out of 100,000 individuals. The incidence of hospitalized stroke for the main stroke types was 8.2 cases in SAH, 29.5 in ICH, and 211 in CI per 100,000 individuals. The standardized annual stroke incidence adjusted to the 2000 World Health Organization population for overall stroke incidence of hospitalized stroke was 131 per 100,000 individuals. Standardized stroke incidence for stroke subtypes was 5.7 cases in SAH, 16.7 in ICH, and 113 in CI per 100,000 individuals.
  
  
  CONCLUSIONS
  These studies provide an initial assessment of the burden of stroke in this part of the world. The estimates of hospitalized stroke in the CR and Eastern Europe suggest that ICH is about three times more common than SAH, and hemorrhagic stroke makes up about 18% of strokes.
authors.affiliation: Department of Neurology, Mayo Clinic, Rochester, New York; Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
authors.forename: Petra
authors.initials: P
authors.lastname: Sedova
authors.affiliation: Department of Neurology, Mayo Clinic, Rochester, New York.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Brown
authors.affiliation: Institute of Health Information and Statistics of the Czech Republic, Prague, Czech Republic.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Zvolsky
authors.affiliation: International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
authors.forename: Pavla
authors.initials: P
authors.lastname: Kadlecova
authors.affiliation: Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
authors.forename: Tomas
authors.initials: T
authors.lastname: Bryndziar
authors.affiliation: Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Kubelka
authors.affiliation: Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
authors.forename: Viktor
authors.initials: V
authors.lastname: Weiss
authors.affiliation: Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
authors.forename: Ondřej
authors.initials: O
authors.lastname: Volný
authors.affiliation: Department of Neurology, University Hospital Brno, and Faculty of Medicine, Masaryk University, Brno, Czech Republic.
authors.forename: Josef
authors.initials: J
authors.lastname: Bednarik
authors.affiliation: Department of Neurology, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic. Electronic address: mikulik@hotmail.com.
authors.forename: Robert
authors.initials: R
authors.lastname: Mikulik
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000453:epidemiology*; D002544:Cerebral Infarction / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies; D017678:Sex Distribution; D020521:Stroke / Q000175:diagnosis / Q000453:epidemiology*; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis / Q000453:epidemiology*; D013997:Time Factors; D055815:Young Adult
keywords: Czech Republic; Stroke; epidemiology; incidence; intracerebral hemorrhage; registry; subarachnoid hemorrhage