title: Effect of a Prior History of Overweight on Return of Menses in Adolescents With Eating Disorders.
abstract: OBJECTIVE
  The purpose of this study was to determine whether a history of overweight, weight suppression, and weight gain during treatment have an effect on return of menses (ROM) in adolescents with eating disorders (EDs).
  
  
  METHODS
  Retrospective chart review of female adolescents presenting to an ED program from January 2007 to June 2009.
  
  
  RESULTS
  One hundred sixty-three participants (mean age, 16.6 ± 2.1 years) met eligibility criteria. The mean median body mass index percent at ROM for those previously overweight was 106.1 ± 11.7 versus 94.2 ± 8.9 for those not previously overweight (p < .001). Both groups needed to gain weight for ROM. Greater weight suppression (odds ratio, 0.90; 95% confidence interval, 0.84-0.98; p = .013) was associated with lower likelihood of ROM, and greater weight gain during treatment (odds ratio, 1.20; 95% confidence interval, 1.07-1.36; p = .002) was associated with higher likelihood of ROM in those not previously overweight.
  
  
  CONCLUSIONS
  Previously overweight amenorrheic patients with EDs needed to be at a higher median body mass index percent for ROM compared to those who were not previously overweight.
authors.affiliation: Division of Adolescent Medicine, Stanford University Medical Center, Palo Alto, California.
authors.forename: Sujatha
authors.initials: S
authors.lastname: Seetharaman
authors.affiliation: Division of Adolescent Medicine, Stanford University Medical Center, Palo Alto, California.
authors.forename: Neville H
authors.initials: NH
authors.lastname: Golden
authors.affiliation: Division of Adolescent Medicine, Stanford University Medical Center, Palo Alto, California.
authors.forename: Bonnie
authors.initials: B
authors.lastname: Halpern-Felsher
authors.affiliation: The Craig Dalsimer Division of Adolescent Medicine, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, Philadelphia, Pennsylvania.
authors.forename: Rebecka
authors.initials: R
authors.lastname: Peebles
authors.affiliation: Pacific Northwest University of Health Sciences, Yakima, Washington.
authors.forename: Allison
authors.initials: A
authors.lastname: Payne
authors.affiliation: Division of Adolescent Medicine, Stanford University Medical Center, Palo Alto, California. Electronic address: carlson2@stanford.edu.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Carlson
mesh_terms: D000293:Adolescent; D000568:Amenorrhea / Q000209:etiology* / Q000523:psychology / Q000628:therapy; D015992:Body Mass Index; D001068:Feeding and Eating Disorders / Q000150:complications* / Q000523:psychology / Q000628:therapy; D005260:Female; D006801:Humans; D050177:Overweight / Q000150:complications* / Q000523:psychology; D012189:Retrospective Studies; D015430:Weight Gain / Q000502:physiology; D015431:Weight Loss / Q000502:physiology
keywords: Adolescents; Amenorrhea; Eating disorders; Overweight; Return of menses