title: Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.
authors.affiliation: DeBartolo Family Personalized Medicine Institute, Division of Population Science, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
authors.forename: J K
authors.initials: JK
authors.lastname: Hicks
authors.affiliation: Department of Genetics, Stanford University, Stanford, California, USA.
authors.forename: K
authors.initials: K
authors.lastname: Sangkuhl
authors.affiliation: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Swen
authors.affiliation: Department of Clinical, Social and Administrative Sciences, College of Pharmacy, and Department of Psychiatry, School of Medicine, University of Michigan, Ann Arbor, Michigan, USA.
authors.forename: V L
authors.initials: VL
authors.lastname: Ellingrod
authors.affiliation: Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
authors.forename: D J
authors.initials: DJ
authors.lastname: Müller
authors.affiliation: Department of Psychiatry, Dokkyo Medical University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shimoda
authors.affiliation: Department of Experimental and Clinical Pharmacology, College of Pharmacy, and Department of Psychiatry, College of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Bishop
authors.affiliation: Division of Clinical and Translational Research, Department of Anesthesiology, Washington University in St, Louis, St, Louis, Missouri, USA.
authors.forename: E D
authors.initials: ED
authors.lastname: Kharasch
authors.affiliation: Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: T C
authors.initials: TC
authors.lastname: Skaar
authors.affiliation: Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy, Kansas City, Missouri and Department of Pediatrics, University of Missouri-Kansas City, Kansas City, Missouri, USA.
authors.forename: A
authors.initials: A
authors.lastname: Gaedigk
authors.affiliation: Center for Molecular Medicine, NorthShore University HealthSystem, Evanston, Illinois, USA.
authors.forename: H M
authors.initials: HM
authors.lastname: Dunnenberger
authors.affiliation: Department of Genetics, Stanford University, Stanford, California, USA.
authors.forename: T E
authors.initials: TE
authors.lastname: Klein
authors.affiliation: Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
authors.forename: K E
authors.initials: KE
authors.lastname: Caudle
authors.affiliation: Division of Research, Federal Institute of Drugs and Medical Devices, Bonn, Germany.
authors.forename: J C
authors.initials: JC
authors.lastname: Stingl
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000493:pharmacokinetics; D065731:Cytochrome P-450 CYP2C19 / Q000235:genetics*; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D004305:Dose-Response Relationship, Drug; D060005:Genotyping Techniques / Q000379:methods*; D006801:Humans; D054539:Medication Therapy Management / Q000592:standards*; D000071184:Pharmacogenomic Variants / Q000235:genetics*; D011110:Polymorphism, Genetic; D016896:Treatment Outcome
chemical_list: D000929:Antidepressive Agents, Tricyclic; D065731:Cytochrome P-450 CYP2C19; D019389:Cytochrome P-450 CYP2D6