title: Synthesis of oxindole from acetanilide via Ir(iii)-catalyzed C-H carbenoid functionalization.
abstract: Herein we disclose the first report on the synthesis of oxindole derivatives from acetanilide via Ir(iii)-catalyzed intermolecular C-H functionalization with diazotized Meldrum's acid. A broad range of substituted anilides were found to react smoothly under the Ir(iii)-catalytic system to afford the corresponding N-protected oxindoles. The N-protecting groups, such as Ac, Bz or Piv, can be easily removed to furnish the oxindole. Various synthetic applications of the synthesized oxindole were also demonstrated.
authors.affiliation: Chemical Science & Technology Division, CSIR-North East Institute of Science and Technology, Jorhat-785006, India. patel.pitambar@gmail.com.
authors.forename: Pitambar
authors.initials: P
authors.lastname: Patel
authors.affiliation: Chemical Science & Technology Division, CSIR-North East Institute of Science and Technology, Jorhat-785006, India. patel.pitambar@gmail.com.
authors.forename: Gongutri
authors.initials: G
authors.lastname: Borah