title: Molecularly imprinted polymer grafted paper-based method for the detection of 17β-estradiol.
abstract: 17β-estradiol (17β-E2) usually is used to promote the growth of animal. Abuse of 17β-E2has become a global food security problem, because the residues in foods can cause endocrine disorder through the food chain. A novel molecularly imprinted polymer (MIP) grafted paper-based method for the sensitive and specific detection of 17β-E2was reported in this work. Results showed that the MIP's optimum synthetic conditions were as follows: 12 mL of acetonitrile was chosen as the solvent; the molar ratio of template molecule, functional monomer and cross linker was 1:12:12. MIP synthesized had a good recognition ability, the limit of detection (LOD) of established detection method for milk and human urine samples could reach 0.25μgL-1.
authors.affiliation: College of Life Science, Shandong Normal University, Jinan, 250014, PR China.
authors.forename: Lei
authors.initials: L
authors.lastname: Xiao
authors.affiliation: College of Life Science, Shandong Normal University, Jinan, 250014, PR China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: College of Life Science, Shandong Normal University, Jinan, 250014, PR China.
authors.forename: Chuanchen
authors.initials: C
authors.lastname: Wu
authors.affiliation: College of Life Science, Shandong Normal University, Jinan, 250014, PR China.
authors.forename: Liying
authors.initials: L
authors.lastname: Han
authors.affiliation: College of Life Science, Shandong Normal University, Jinan, 250014, PR China. Electronic address: zhanghongyan@sdnu.edu.cn.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zhang
mesh_terms: D000818:Animals; D004958:Estradiol / Q000032:analysis* / Q000652:urine*; D006801:Humans; D057230:Limit of Detection; D008892:Milk / Q000737:chemistry*; D054802:Molecular Imprinting / Q000379:methods*; D010209:Paper; D011108:Polymers
chemical_list: D011108:Polymers; D004958:Estradiol
keywords: 17β-Estradiol; Molecularly imprinted polymer; Paper-based method