title: Effect of a Connective Tissue Graft in Combination With a Single Flap Approach in the Regenerative Treatment of Intraosseous Defects[Formula: see text].
abstract: In the attempt to limit the post-surgery increase in buccal gingival recession (bREC), effect of a connective tissue graft (CTG) when combined with a buccal single flap approach (SFA) in the regenerative treatment of intraosseous defects is evaluated.
  
  
  
  Data related to 30 patients with an intraosseous defect treated with a buccal SFA with (SFA+CTG group; n = 15) or without (SFA group; n = 15) placement of a CTG and regenerative treatment were retrospectively derived at three clinical centers. bREC and probing parameters were assessed at presurgery and 6 months post-surgery.
  
  
  
  In addition to a significant attachment gain and probing depth reduction, adjunctive use of a CTG to a buccal SFA in the regenerative treatment of periodontal intraosseous defects associated with a buccal bone dehiscence resulted in a limited post-surgery bREC, a lower prevalence of defects with a clinically detectable apical displacement of the gingival margin, and an increase in gingival width and thickness.
  
  
  
  Adjunctive use of a CTG in the regenerative treatment of intraosseous defects associated with buccal bone dehiscence accessed by buccal SFA may support the stability of the gingival profile.
authors.affiliation: Research Center for the Study of Periodontal and Peri-Implant Diseases, University of Ferrara, Ferrara, Italy.|Operative Unit of Dentistry, University-Hospital, Ferrara, Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Trombelli
authors.affiliation: Research Center for the Study of Periodontal and Peri-Implant Diseases, University of Ferrara, Ferrara, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Simonelli
authors.affiliation: Research Center for the Study of Periodontal and Peri-Implant Diseases, University of Ferrara, Ferrara, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Minenna
authors.affiliation: Operative Unit of Dentistry, University-Hospital, Ferrara, Italy.|Institute for Inpatient Treatment and Scientific Studies Foundation, Ca' Granda Polyclinic, Milan, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Rasperini
authors.affiliation: Research Center for the Study of Periodontal and Peri-Implant Diseases, University of Ferrara, Ferrara, Italy.|Operative Unit of Dentistry, University-Hospital, Ferrara, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Farina
mesh_terms: D000328:Adult; D000368:Aged; D003238:Connective Tissue / Q000637:transplantation*; D005260:Female; D005889:Gingival Recession / Q000601:surgery*; D005893:Gingivoplasty / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013524:Surgical Flaps; D016896:Treatment Outcome
keywords: Alveolar bone loss; enamel matrix proteins; gingival recession; periodontitis; reconstructive surgical procedures; surgical flaps