title: The 2016 World Health Organization Classification of tumours of the Central Nervous System: what the paediatric neuroradiologist needs to know.
abstract: The recently published 2016 World Health Organization (WHO) classification of tumours of the Central Nervous System (CNS) introduces a number of significant changes from the previous edition. Based on an improved understanding of the genetic and molecular basis of tumorigenesis there has been a shift towards defining tumours by means of these characteristics in addition to their histological features, thus providing an integrated diagnosis. In this article, we will provide a concise overview of the salient changes in the 2016 WHO classification of tumours of the CNS that are of relevance to the paediatric neuroradiologist when it comes to day-to-day reporting.
authors.affiliation: Department of Radiology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
authors.forename: Sahil
authors.initials: S
authors.lastname: Chhabda
authors.affiliation: Developmental Biology and Cancer Programme, UCL Great Ormond Street Institute of Child Heath, London, UK.
authors.forename: Olivia
authors.initials: O
authors.lastname: Carney
authors.affiliation: Developmental Biology and Cancer Programme, UCL Great Ormond Street Institute of Child Heath, London, UK.
authors.forename: Felice
authors.initials: F
authors.lastname: D'Arco
authors.affiliation: Department of Pathology, Great Ormond Street Hospital NHS Foundation Trust, London, UK.
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Jacques
authors.affiliation: Developmental Biology and Cancer Programme, UCL Great Ormond Street Institute of Child Heath, London, UK.
authors.forename: Kshitij
authors.initials: K
authors.lastname: Mankad
keywords: Central nervous system neoplasms; World Health Organization (WHO); classification, diagnostic imaging; paediatric