title: Latest generation of flat detector CT as a peri-interventional diagnostic tool: a comparative study with multidetector CT.
abstract: OBJECTIVE
  Flat detector CT (FDCT) has been used as a peri-interventional diagnostic tool in numerous studies with mixed results regarding image quality and detection of intracranial lesions. We compared the diagnostic aspects of the latest generation FDCT with standard multidetector CT (MDCT).
  
  
  METHODS
  102 patients were included in our retrospective study. All patients had undergone interventional procedures. FDCT was acquired peri-interventionally and compared with postinterventional MDCT regarding depiction of ventricular/subarachnoidal spaces, detection of intracranial hemorrhage, and delineation of ischemic lesions using an ordinal scale. Ischemic lesions were quantified with the Alberta Stroke Program Early CT Scale (ASPECTS) on both examinations. Two neuroradiologists with varying grades of experience and a medical student scored the anonymized images separately, blinded to the clinical history.
  
  
  RESULTS
  The two methods were of equal diagnostic value regarding evaluation of the ventricular system and the subarachnoidal spaces. Subarachnoidal, intraventricular, and parenchymal hemorrhages were detected with a sensitivity of 95%, 97%, and 100% and specificity of 97%, 100%, and 99%, respectively, using FDCT. Gray-white differentiation was feasible in the majority of FDCT scans, and ischemic lesions were detected with a sensitivity of 71% on FDCT, compared with MDCT scans. The mean difference in ASPECTS values on FDCT and MDCT was 0.5 points (95% CI 0.12 to 0.88).
  
  
  CONCLUSIONS
  The latest generation of FDCT is a reliable and accurate tool for the detection of intracranial hemorrhage. Gray-white differentiation is feasible in the supratentorial region.
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Johanna Rosemarie
authors.initials: JR
authors.lastname: Leyhe
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Tsogkas
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Amélie Carolina
authors.initials: AC
authors.lastname: Hesse
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Behme
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Schregel
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Ismini
authors.initials: I
authors.lastname: Papageorgiou
authors.affiliation: Department of Neurology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Liman
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Knauth
authors.affiliation: Department of Neuroradiology, University Medicine Goettingen, Goettingen, Germany.
authors.forename: Marios-Nikos
authors.identifier: http://orcid.org/0000-0002-0016-414X
authors.initials: MN
authors.lastname: Psychogios
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000000981:diagnostic imaging* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods* / Q000639:trends*; D012189:Retrospective Studies; D020521:Stroke / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000639:trends
keywords: Angiography; CT; Hemorrhage; Stroke