title: Coexistence of optic pit and coloboma of iris, lens, and choroid: a case report.
abstract: A 42-year-old woman was admitted to our clinic with a complaint of glare in both eyes. Biomicroscopic examination of both the eyes revealed iris and lens colobomas in the inferior quadrant. Fundus examination of the right eye revealed an oval and gray inferotemporal optic pit and two choroid colobomas in the inferior quadrant. In the left eye, two choroid colobomas were detected that were inferior to the optic nerve head. Furthermore, a 21-year-old man presented to our clinic for a routine ophthalmologic examination. Bilateral biomicroscopic examination was normal. Fundus examination of the left eye revealed an oval and gray inferotemporal optic pit and a choroid coloboma that was inferior to the optic nerve head. Here we describe optic pits co-occurring with iris, lens, and choroidal colobomas. On the basis of these cases, a defect in the closure of the embryonic fissure is the most plausible etiology of the optic pit.
authors.affiliation: Ophthalmology Department, Trakya University, Edirne, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Özelce
authors.affiliation: Ophthalmology Department, Trakya University, Edirne, Turkey.
authors.forename: Vuslat
authors.initials: V
authors.lastname: Gürlü
authors.affiliation: Ophthalmology Department, Trakya University, Edirne, Turkey.
authors.forename: Hande
authors.initials: H
authors.lastname: Güçlü
authors.affiliation: Ophthalmology Department, Trakya University, Edirne, Turkey.
authors.forename: Sadık Altan
authors.initials: SA
authors.lastname: Özal
mesh_terms: D000328:Adult; D002829:Choroid / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D003103:Coloboma / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods; D005654:Fundus Oculi; D006801:Humans; D007498:Iris / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D007908:Lens, Crystalline / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D009898:Optic Disk / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000379:methods; D014792:Visual Acuity; D055815:Young Adult