title: Malignant Transformation of Hepatocellular Adenoma.
abstract: The patient was a 20-year-old male in whom a hepatic hypervascular mass accompanied by intratumoral hemorrhage was detected on examination for epigastric pain. Based on the enlargement of the mass and diagnostic imaging, hepatocellular adenoma (HCA) was suspected and hepatectomy was performed. The lesion was diagnosed as malignant transformation of β-catenin-activated HCA. There are only few reports of cases with malignant transformation of HCA in Japan; it is necessary to accumulate cases to investigate it.
authors.affiliation: Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
authors.forename: Wing Yee
authors.initials: WY
authors.lastname: Kwok
authors.forename: Satoru
authors.initials: S
authors.lastname: Hagiwara
authors.forename: Naoshi
authors.initials: N
authors.lastname: Nishida
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Watanabe
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Sakurai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ida
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Minami
authors.forename: Masahiro
authors.initials: M
authors.lastname: Takita
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Minami
authors.forename: Mina
authors.initials: M
authors.lastname: Iwanishi
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Chishina
authors.forename: Masashi
authors.initials: M
authors.lastname: Kono
authors.forename: Kazuomi
authors.initials: K
authors.lastname: Ueshima
authors.forename: Yoriaki
authors.initials: Y
authors.lastname: Komeda
authors.forename: Tadaaki
authors.initials: T
authors.lastname: Arizumi
authors.forename: Eisuke
authors.initials: E
authors.lastname: Enoki
authors.forename: Takuya
authors.initials: T
authors.lastname: Nakai
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Kumabe
authors.forename: Osamu
authors.initials: O
authors.lastname: Nakashima
authors.forename: Fukuo
authors.initials: F
authors.lastname: Kondo
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kudo
mesh_terms: D018248:Adenoma, Liver Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D055815:Young Adult