title: Exploring the Reactivity of Nitro-Activated 1,3-Enynes in an Organocatalytic One-Pot, Three-Component Coupling Reaction: A Tandem Catalytic Approach to a Novel 3-Nitrochroman Scaffold.
abstract: A tandem catalytic strategy enabling one-pot, three-component couplings of electron-rich phenols, 2-nitro 1,3-enynes, and vinyl ketones was achieved. This chemistry combined mechanistically distinct [3 + 3]-annulation and nitro-Michael addition using a single squaramide catalyst, leading to the construction of novel chiral quaternary 3-nitrochromane architecture with high chemo-, regio-, and stereoselectivity.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Jun-Bing
authors.initials: JB
authors.lastname: Lin
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Yin-Na
authors.initials: YN
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Jin-Yu
authors.initials: JY
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, P. R. China.
authors.forename: Peng-Fei
authors.identifier: 0000-0001-8144-9069
authors.initials: PF
authors.lastname: Xu