title: LONG-TERM ANATOMICAL AND FUNCTIONAL OUTCOMES FOLLOWING VITRECTOMY FOR ADVANCED COATS DISEASE.
abstract: OBJECTIVE
  To assess the long-term anatomical and functional results of vitreoretinal surgery in patients with advanced Coats disease.
  
  
  METHODS
  Retrospective analysis of 23 patients who underwent 23-gauge pars plana vitrectomy combined with transscleral cryotherapy, laser photocoagulation, and intraocular tamponade between 2005 and 2014 and had a follow-up of at least 1 year. The primary outcomes were mean visual acuity and anatomical success.
  
  
  RESULTS
  The average age at the time of surgery was 8.7 ± 1.3 years (range, 2-18 years). The mean follow-up period was 55.2 ± 31 months (range, 12-120 months). In 16 eyes (70%), further treatment was not necessary. In the remaining 7 patients (30%), revision surgery with silicone oil tamponade was required. In 20 eyes (87%), the retina was reattached. At the final visit, 8 eyes (35%) had improved mean Snellen visual acuity from 20/1,000 at initial presentation to 20/160, 3 eyes (13%) showed stabilization, and 6 eyes (26%) had decline in visual acuity. No enucleation was necessary, and no progression to neovascular glaucoma was observed.
  
  
  CONCLUSIONS
  Pars plana vitrectomy combined with cryotherapy, laser photocoagulation, and intraocular tamponade could be an effective treatment option for advanced Coats disease. Despite surgery, disease-related complications remained high, but the main aim of management in these young patients is functional and anatomical stability.
authors.affiliation: Istanbul Retina Institute, Istanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Karacorlu
authors.forename: Mumin
authors.initials: M
authors.lastname: Hocaoglu
authors.forename: Isil
authors.initials: I
authors.lastname: Sayman Muslubas
authors.forename: Serra
authors.initials: S
authors.lastname: Arf
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D017679:Cryotherapy / Q000379:methods; D058450:Endotamponade / Q000379:methods; D005260:Female; D006801:Humans; D017075:Laser Coagulation / Q000379:methods; D008297:Male; D058456:Retinal Telangiectasis / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*