title: Nationwide Survey of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Children in the United States.
abstract: Although Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious, life-threatening reactions to drug therapies, no efforts have been made to investigate the comprehensive change in epidemiology with respect to age, sex, and race and ethnicity in children. The risk of death was 0.3% to 1.5%, and the highest hospitalization rates were in children 15 to 19 years of age, boys, and black children. The highest proportions of hospitalizations were children with very low household income, those with private insurance, and those treated at large urban teaching hospitals in the West. A significant winter-autumn predominance was observed.
authors.affiliation: T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Okubo
authors.affiliation: T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
authors.forename: Kotaro
authors.initials: K
authors.lastname: Nochioka
authors.affiliation: T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
authors.forename: Marcia A
authors.initials: MA
authors.lastname: Testa
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012959:Socioeconomic Factors; D013262:Stevens-Johnson Syndrome / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D055815:Young Adult