title: Polypoidal Choroidal Vasculopathy Occurring in the Context of Large Colloid Drusen.
abstract: The authors report, for the first time, an association between large colloid drusen (LCD) and choroidal neovascularization in a 58-year-old man. Multimodal imaging confirmed the diagnosis of LCD in both eyes and polypoidal choroidal vasculopathy in the left eye. The patient was treated with monthly intravitreal injections of aflibercept (Eylea; Regeneron, Tarrytown, NY). The authors hypothesize that these deposits are probably associated with retinal pigment epithelium dysfunction and could thus lead to delayed neovascularization and atrophy. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:1154-1156.].
authors.forename: Thibaud
authors.initials: T
authors.lastname: Mathis
authors.forename: Laurent
authors.initials: L
authors.lastname: Kodjikian
authors.forename: Martine
authors.initials: M
authors.lastname: Mauget-Faÿsse
authors.forename: Audrey
authors.initials: A
authors.lastname: Feldman
mesh_terms: D002829:Choroid / Q000098:blood supply / Q000473:pathology*; D020256:Choroidal Neovascularization / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D058449:Intravitreal Injections; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000175:diagnosis* / Q000188:drug therapy; D040262:Receptors, Vascular Endothelial Growth Factor / Q000008:administration & dosage / Q000037:antagonists & inhibitors; D011993:Recombinant Fusion Proteins / Q000008:administration & dosage; D015593:Retinal Drusen / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods; D014792:Visual Acuity
chemical_list: D011993:Recombinant Fusion Proteins; C533178:aflibercept; D040262:Receptors, Vascular Endothelial Growth Factor