title: Vector synthesis high-resolution electrocardiography, atrial natriuretic peptide and N-terminal prohormone brain natriuretic peptide for estimation of cardiac load in pregnancy.
abstract: OBJECTIVE
  We analyzed atrial natriuretic peptide (ANP), N-terminal pro-brain natriuretic natriuretic peptide (NT-proBNP) and vector synthesis high-resolution electrocardiography (ECG), to estimate cardiac load with circulatory dynamic change from pregnancy through the post-partum period.
  
  
  METHODS
  The subjects were singleton pregnant women (n = 19), who were divided into three stages: stage 1, 34-36 weeks of gestation; stage 2, 2-6 post-partum days; and stage 3, 1-3 months after delivery. Vector synthesis high-resolution ECG, ANP and NT-proBNP were analyzed for all subjects.
  
  
  RESULTS
  A pregnant woman with massive uterin liomyoma expressed largest the corrected recover time (RTc) dispersion in I + II of tow Dimensional (2D) color distribution map ANP and NT-proBNP were significantly higher in stage 2 than in stages 1 and 3.
  
  
  CONCLUSIONS
  ANP, NT-proBNP and vector synthesis high-resolution ECG there might be able to evaluate cardiac load of normal pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Iwate, Japan.
authors.forename: Shino
authors.initials: S
authors.lastname: Tanaka
authors.affiliation: Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Iwate, Japan.
authors.forename: Rie
authors.initials: R
authors.lastname: Oyama
authors.affiliation: Department of Clinical Genetics, Iwate Medical University, Morioka, Iwate, Japan.
authors.forename: Akimune
authors.initials: A
authors.lastname: Fukushima
authors.affiliation: Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Iwate, Japan.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kikuchi
authors.affiliation: Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Iwate, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Sugiyama
mesh_terms: D000328:Adult; D009320:Atrial Natriuretic Factor / Q000097:blood*; D001794:Blood Pressure; D015992:Body Mass Index; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D005865:Gestational Age; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D049590:Postpartum Period; D011247:Pregnancy; D055815:Young Adult
chemical_list: D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain; D009320:Atrial Natriuretic Factor
keywords: N-terminal prohormone brain natriuretic peptide; atrial natriuretic peptide; cardiac load; pregnancy; vector synthesis high-resolution electrocardiography RTc dispersion