title: Perfluoroalkyl Analogues of Diethylaminosulfur Trifluoride: Reagents for Perfluoroalkylthiolation of Active Methylene Compounds under Mild Conditions.
abstract: Trifluoromethyl diethylaminosulfur difluoride (CF3-DAST) was found to be an efficient reagent for the trifluoromethylthiolation of α-methylene-β-keto esters providing α-trifluoromethylthio-β-keto esters in good to high yields. α-Methylene-β-keto sulfones were also accepted as substrates by CF3-DAST to furnish the corresponding α-trifluoromethylthio compounds. This strategy can be extended to perfluoroalkylthiolation reactions using perfluoroethyl-DAST (C2F5-DAST) and perfluoropropyl-DAST (C3F7-DAST).
authors.affiliation: Department of Nanopharmaceutical Sciences & Department of Frontier Materials, Nagoya Institute of Technology , Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Ibrayim
authors.initials: I
authors.lastname: Saidalimu
authors.affiliation: Department of Nanopharmaceutical Sciences & Department of Frontier Materials, Nagoya Institute of Technology , Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Shugo
authors.initials: S
authors.lastname: Suzuki
authors.affiliation: Department of Nanopharmaceutical Sciences & Department of Frontier Materials, Nagoya Institute of Technology , Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Yoshioka
authors.affiliation: Department of Nanopharmaceutical Sciences & Department of Frontier Materials, Nagoya Institute of Technology , Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Etsuko
authors.initials: E
authors.lastname: Tokunaga
authors.affiliation: Department of Nanopharmaceutical Sciences & Department of Frontier Materials, Nagoya Institute of Technology , Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Norio
authors.identifier: 0000-0002-3742-4064
authors.initials: N
authors.lastname: Shibata