title: Lifestyle Intervention on Metabolic Syndrome and its Impact on Quality of Life: A Randomized Controlled Trial.
abstract: BACKGROUND
  Lifestyle intervention programs can reduce the prevalence of metabolic syndrome (MetS) and, therefore, reduce the risk for cardiac disease, one of the main public health problems nowadays.
  
  
  OBJECTIVE
  The aim of this study was to compare the effects of three types of approach for lifestyle change programs in the reduction of metabolic parameters, and to identify its impact on the quality of life (QOL) of individuals with MetS.
  
  
  METHODS
  A randomized controlled trial included 72 individuals with MetS aged 30-59 years. Individuals were randomized into three groups of multidisciplinary intervention [Standard Intervention (SI) - control group; Group Intervention (GI); and Individual Intervention (II)] during 12 weeks. The primary outcome was change in the metabolic parameters, and secondarily, the improvement in QOL measures at three moments: baseline, 3 and 9 months.
  
  
  RESULTS
  Group and individual interventions resulted in a significant reduction in body mass index, waist circumference, systolic blood pressure at 3 months and the improvement of QOL, although it was significantly associated with the physical functioning domain. However, these changes did not remain 6 months after the end of intervention. Depression and anxiety were significantly associated with worse QOL, although they showed no effect on the response to intervention.
  
  
  CONCLUSIONS
  Multidisciplinary intervention, especially in a group, might be an effective and economically feasible strategy in the control of metabolic parameters of MetS and improvement of QOL compared to SI, even in a dose-effect relationship.
authors.affiliation: Pontifícia Universidade Católica do Rio Grande do Sul, RS, Brazil.
authors.forename: Patrícia Pozas
authors.initials: PP
authors.lastname: Saboya
authors.affiliation: Pontifícia Universidade Católica do Rio Grande do Sul, RS, Brazil.
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Bodanese
authors.affiliation: Pontifícia Universidade Católica do Rio Grande do Sul, RS, Brazil.
authors.forename: Paulo Roberto
authors.initials: PR
authors.lastname: Zimmermann
authors.affiliation: Pontifícia Universidade Católica do Rio Grande do Sul, RS, Brazil.
authors.forename: Andreia da Silva
authors.initials: AD
authors.lastname: Gustavo
authors.affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre, RS, Brazil.
authors.forename: Fabricio Edler
authors.initials: FE
authors.lastname: Macagnan
authors.affiliation: Pontifícia Universidade Católica do Rio Grande do Sul, RS, Brazil.
authors.forename: Ana Pandolfo
authors.initials: AP
authors.lastname: Feoli
authors.affiliation: Pontifícia Universidade Católica do Rio Grande do Sul, RS, Brazil.
authors.forename: Margareth da Silva
authors.initials: MD
authors.lastname: Oliveira
mesh_terms: D000328:Adult; D000886:Anthropometry; D001007:Anxiety / Q000503:physiopathology; D001794:Blood Pressure / Q000502:physiology; D003863:Depression / Q000503:physiopathology; D004035:Diet Therapy / Q000379:methods; D004522:Educational Status; D005081:Exercise Therapy / Q000379:methods; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D017533:Marital Status; D024821:Metabolic Syndrome / Q000523:psychology / Q000628:therapy*; D008875:Middle Aged; D010348:Patient Care Team; D011788:Quality of Life; D015203:Reproducibility of Results; D012307:Risk Factors; D040242:Risk Reduction Behavior; D013997:Time Factors; D016896:Treatment Outcome