title: Macrophages Tell the Non-Professionals What to Do.
abstract: Phagocytosis by professional and non-professional phagocytes plays a critical role in tissue homeostasis and the immune response. Using an airway inflammation model, Han et al. (2016) report in Nature that macrophages secrete IGF-1 to signal epithelial cells to stop ingesting apoptotic cells while increasing the uptake of anti-inflammatory macrophage-derived microvesicles.
authors.affiliation: INRS-Institut Armand-Frappier and Centre for Host-Parasite Interactions, Laval, QC H7V 1B7, Canada.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Arango Duque
authors.affiliation: INRS-Institut Armand-Frappier and Centre for Host-Parasite Interactions, Laval, QC H7V 1B7, Canada. Electronic address: albert.descoteaux@iaf.inrs.ca.
authors.forename: Albert
authors.initials: A
authors.lastname: Descoteaux
mesh_terms: D017209:Apoptosis / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D010586:Phagocytes / Q000276:immunology; D010587:Phagocytosis / Q000276:immunology