title: Synthesis of carbon-13 labeled oxalates exhibiting extended nuclear singlet state lifetimes.
abstract: Unsymmetrical perdeuterated doubly13C labelled oxalates exhibit extended lifetimes in the nuclear singlet state. Synthesis of 1,213C2oxalates from commercially available precursors is described, facilitating preparation of unsymmetrical oxalates in a controlled manner.
authors.affiliation: Department of Chemistry, University of Southampton, Southampton, UK.
authors.forename: Lynda J
authors.identifier: 0000-0002-5678-0814
authors.initials: LJ
authors.lastname: Brown
authors.affiliation: Department of Chemistry, University of Southampton, Southampton, UK.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Pileio
authors.affiliation: Department of Chemistry, University of Southampton, Southampton, UK.
authors.forename: Malcolm H
authors.initials: MH
authors.lastname: Levitt
authors.affiliation: Department of Chemistry, University of Southampton, Southampton, UK.
authors.forename: Richard C D
authors.initials: RC
authors.lastname: Brown
mesh_terms: D002247:Carbon Isotopes / Q000737:chemistry; D010070:Oxalates / Q000737:chemistry*; D019275:Radiopharmaceuticals / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002247:Carbon Isotopes; D010070:Oxalates; D019275:Radiopharmaceuticals
keywords: carbon-13; deuterium; hyperpolarized agents; nuclear singlet state; oxalates