title: Analysis of the origin of birth defects in pregnant women from the Kujawy-Pomerania Region.
abstract: The aim of the study was to analyze the origin of birth defects in pregnant women from the Kujawy-Pomerania Region, and to identify factors affecting the formation of developmental disorders in the Province.
  
  
  
  The correlation between maternal age and fetal defects was investigated. We also attempted to determine whether environmental or family factors play a role in the formation of fetal abnormalities.
  
  
  
  The analysis confirmed a correlation between the incidence of chromosomal aberrations and maternal age.
  
  
  
  Higher rates of neural tube defects were observed in fetuses born to mothers who did not take folic acid. The influence of other factors on developmental anomalies was not confirmed.
authors.affiliation: Multi-Specialty County Hospital in Bydgoszcz Division of Maternal-Fetal Medicine, Gynecology and Neonatology at Nicolaus Copernicus University Ludwik Rydygier Collegium Medicum in Bydgoszcz. laudaa@op.pl.
authors.forename: Anna
authors.initials: A
authors.lastname: Lauda-Świeciak
authors.forename: Szymon
authors.initials: S
authors.lastname: Bednarek
authors.forename: Jacek
authors.initials: J
authors.lastname: Skórczewski
authors.forename: Dariusz
authors.initials: D
authors.lastname: Borowski
authors.forename: Mariusz
authors.initials: M
authors.lastname: Dubiel
mesh_terms: D000328:Adult; D025063:Chromosome Disorders / Q000453:epidemiology; D004314:Down Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage*; D006801:Humans; D015994:Incidence; D008423:Maternal Age; D008875:Middle Aged; D009436:Neural Tube Defects / Q000175:diagnosis* / Q000453:epidemiology* / Q000517:prevention & control; D011044:Poland / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D011296:Prenatal Diagnosis / Q000379:methods*; D012189:Retrospective Studies; D012307:Risk Factors; D016216:Ultrasonography, Prenatal / Q000706:statistics & numerical data*; D014803:Vitamin B Complex / Q000008:administration & dosage*
chemical_list: D014803:Vitamin B Complex; D005492:Folic Acid
keywords: congenital malformations; developmental anomalies; fetal abnormalities; genetically-determined abnormalities