title: [Risk factors for recurrent wheezing in infants and young children suffering from dust mite allergy after their first wheezing].
abstract: OBJECTIVE
  To investigate the risk factors for recurrent wheezing in infants and young children suffering from dust mite allergy after their first wheezing.
  
  
  METHODS
  A total of 1 236 infants and young children who experienced a first wheezing episode and were hospitalized between August 2014 and February 2015 were enrolled, among whom 387 were allergic to dust mites. These infants and young children were followed up to 1 year after discharge. A total of 67 infants and young children who experienced 3 or more recurrent wheezing episodes within 1 year were enrolled as the recurrent wheezing group, while 84 infants and young children who did not experience recurrent wheezing during follow-up were enrolled as the control group. Univariate analysis and multivariate logistic stepwise regression analysis were performed to investigate the risk factors for recurrent wheezing in these patients.
  
  
  RESULTS
  The univariate analysis showed that the age on admission, wheezing time before admission, Mycoplasma pneumoniae infection rate, and influenza virus infection rate were associated with recurrent wheezing. The multivariate logistic stepwise regression analysis showed that the older age on admission (OR=2.21, P=0.04) and Mycoplasma pneumoniae infection (OR=3.54, P=0.001) were independent risk factors for recurrent wheezing.
  
  
  CONCLUSIONS
  Infants and young children who are allergic to dust mites, especially young children, have a significantly increased risk of recurrent wheezing if they are complicated by Mycoplasma pneumoniae infection during the first wheezing episode.
authors.affiliation: Department of Pediatrics, Zhangzhou Hospital, Fujian Medical University, Zhangzhou, Fujian 363000, China. 1219665977@qq.com.
authors.forename: Yan-Zhen
authors.initials: YZ
authors.lastname: Yang
authors.forename: Meng-Yun
authors.initials: MY
authors.lastname: Cai
authors.forename: Bao-Zhong
authors.initials: BZ
authors.lastname: Zhang
authors.forename: Bing-Xin
authors.initials: BX
authors.lastname: Zhou
authors.forename: Rou
authors.initials: R
authors.lastname: Chen
authors.forename: Run-Tao
authors.initials: RT
authors.lastname: Fang
mesh_terms: D000818:Animals; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D007223:Infant; D016015:Logistic Models; D008297:Male; D039981:Pyroglyphidae / Q000276:immunology*; D012008:Recurrence; D012135:Respiratory Sounds / Q000209:etiology*; D012307:Risk Factors