title: Polycystic Ovary Syndrome Presents Higher Sympathetic Cardiac Autonomic Modulation that is not altered by Strength Training.
abstract: Polycystic ovary syndrome (PCOS) may present important comorbidities, such as cardiovascular and metabolic diseases, which are often preceded by changes in cardiac autonomic modulation. Different types of physical exercises are frequently indicated for the prevention and treatment of PCOS. However, little is known about the effects of strength training on the metabolic, hormonal, and cardiac autonomic parameters. Therefore, our aim was to investigate the effects of strength training on the autonomic modulation of heart rate variability (HRV) and its relation to endocrine-metabolic parameters in women with PCOS. Fifty-three women were divided into two groups: CONTROL (n=26) and PCOS (n=27). The strength training lasted 4 months, which was divided into mesocycles of 4 weeks each. The training load started with 70% of one repetition maximum (1RM). Blood samples were collected before and after intervention for analysis of fasting insulin and glucose, HOMA-IR, testosterone, androstenedione and testosterone/androstenedione (T/A) ratio. Spectral analysis of HRV was performed to assess cardiac autonomic modulation indexes. The PCOS group presented higher insulin and testosterone levels, T/A ratio, along with increased sympathetic cardiac autonomic modulation before intervention. The training protocol used did not cause any change of endocrine-metabolic parameters in the CONTROL group. Interestingly, in the PCOS group, reduced testosterone levels and T/A ratio. Additionally, strength training did not have an effect on the spectral parameter values of HRV obtained in both groups. Strength training was not able to alter HRV autonomic modulation in women with PCOS, however may reduce testosterone levels and T/A ratio.
authors.affiliation: Department of Biomechanics, Medicine and Rehabilitation, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, BRAZIL.
authors.forename: Victor B
authors.initials: VB
authors.lastname: Ribeiro
authors.affiliation: Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, BRAZIL.
authors.forename: Gislaine S
authors.initials: GS
authors.lastname: Kogure
authors.affiliation: Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, BRAZIL.
authors.forename: Rosana M
authors.initials: RM
authors.lastname: Reis
authors.affiliation: Department of Biomechanics, Medicine and Rehabilitation, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, BRAZIL.
authors.forename: Ada C
authors.initials: AC
authors.lastname: Gastaldi
authors.affiliation: Department of Biomechanics, Medicine and Rehabilitation, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, BRAZIL.
authors.forename: João E
authors.initials: JE
authors.lastname: DE Araújo
authors.affiliation: Department of Biomechanics, Medicine and Rehabilitation, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, BRAZIL.
authors.forename: José H
authors.initials: JH
authors.lastname: Mazon
authors.affiliation: Cardiopulmonary Physiotherapy Laboratory, Department of Physical Therapy, Federal University of São Carlos, São Carlos, São Paulo, BRAZIL.
authors.forename: Audrey
authors.initials: A
authors.lastname: Borghi
authors.affiliation: Department of Biomechanics, Medicine and Rehabilitation, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, BRAZIL.
authors.forename: Hugo C D
authors.initials: HC
authors.lastname: Souza
keywords: Heart rate variability; physical exercise