title: An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells.
abstract: A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Nahyun
authors.initials: N
authors.lastname: Kwon
authors.affiliation: Department of Energy Systems Research, Ajou University, Suwon 443-749, Korea. kimhm@ajou.ac.kr.
authors.forename: Myoung Ki
authors.initials: MK
authors.lastname: Cho
authors.affiliation: Department of Energy Systems Research, Ajou University, Suwon 443-749, Korea. kimhm@ajou.ac.kr.
authors.forename: Sang Jun
authors.initials: SJ
authors.lastname: Park
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Dayoung
authors.initials: D
authors.lastname: Kim
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Sang-Jip
authors.initials: SJ
authors.lastname: Nam
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr and College of Science, University of Shanghai for Science and Technology, Shanghai, China. cuilei15@usst.edu.cn.
authors.forename: Lei
authors.initials: L
authors.lastname: Cui
authors.affiliation: Department of Energy Systems Research, Ajou University, Suwon 443-749, Korea. kimhm@ajou.ac.kr.
authors.forename: Hwan Myung
authors.identifier: 0000-0002-4112-9009
authors.initials: HM
authors.lastname: Kim
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Juyoung
authors.identifier: 0000-0002-1728-3970
authors.initials: J
authors.lastname: Yoon
mesh_terms: D045744:Cell Line, Tumor; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D036641:Microscopy, Fluorescence, Multiphoton; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000032:analysis*; D061848:Optical Imaging; D011422:Propionates / Q000737:chemistry*; D011809:Quinones / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D011422:Propionates; D011809:Quinones; D016660:NAD(P)H Dehydrogenase (Quinone); C447479:NQO1 protein, human; C029658:propionic acid