title: Precision Medicine with TGF-β Inhibition Using Tumor Explants: Comment on "Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-β Small Molecule Inhibitor" by N. Sumru Bayin et al.
abstract: In a new report, Bayin et al. described an ex vivo explant model to test the patient-specific response to transforming growth factor-β inhibition in high-grade gliomas.
authors.affiliation: Department of Stem Cell Biology, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Haidong
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Stem Cell Biology, Cleveland Clinic, Cleveland, OH, USA; Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA. Electronic address: yuj2@ccf.org.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Yu
mesh_terms: D001932:Brain Neoplasms; D005910:Glioma; D006801:Humans; D057285:Precision Medicine; D018125:Receptors, Transforming Growth Factor beta; D015398:Signal Transduction / Q000187:drug effects; D016212:Transforming Growth Factor beta
chemical_list: D018125:Receptors, Transforming Growth Factor beta; D016212:Transforming Growth Factor beta