title: Prevention and Infection Management in Mechanical Circulatory Support Device Recipients.
abstract: There are currently no guidelines for the management of infection and its prevention in mechanical circulatory support (MCS) device recipients. The International Society of Heart and Lung Transplantation (ISHLT) has initiated a multidisciplinary collaboration for the creation of a consensus document to guide clinicians in infection prevention and management in MCS patients. Most medical centers use local protocols that are based on expert opinion. MCS recipients are debilitated and have some immunological dysfunction. Over the years there have been technical advancements with smaller devices and drivelines with improved durability. The pulsatile devices have been replaced with newer-generation continuous-flow devices. Patient are living longer with MCSs for bridge to transplant (BTT) and destination therapy (DT). MCS centers have improved patient management by introducing standardized driveline protocols, leading to reduced infection rates among MCS recipients.
authors.affiliation: Infectious Diseases Division, kusne.shimon@mayo.edu.
authors.forename: Shimon
authors.initials: S
authors.lastname: Kusne
authors.affiliation: Cardiothoracic Surgery Division, Mayo Clinic, Phoenix, Arizona; and.
authors.forename: Linda
authors.initials: L
authors.lastname: Staley
authors.affiliation: Cardiothoracic Surgery Division, Cedars-Sinai Medical Center, Los Angeles, California.
authors.forename: Francisco
authors.initials: F
authors.lastname: Arabia
mesh_terms: D019072:Antibiotic Prophylaxis; D003131:Combined Modality Therapy; D019468:Disease Management; D006353:Heart-Assist Devices / Q000009:adverse effects* / Q000145:classification; D006801:Humans; D017053:Infection Control; D065286:Prophylactic Surgical Procedures; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D012307:Risk Factors