title: Assisted Living in the Atheroma: Elderly Macrophages Promote Plaques.
abstract: Age dominates as a risk factor for human atherosclerosis, yet the underlying mechanisms remain elusive. A recent report described accumulation of senescent cells in atheromata of hypercholesterolemic mice and provides novel insights into how genes expressed by aging cells associate with the characteristics of human plaques implicated in cardiovascular events.
authors.affiliation: Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: plibby@bwh.harvard.edu.
authors.forename: Peter
authors.initials: P
authors.lastname: Libby
mesh_terms: D000368:Aged; D000818:Animals; D050197:Atherosclerosis; D006801:Humans; D008264:Macrophages; D051379:Mice; D058226:Plaque, Atherosclerotic