title: Natural Approaches in Diabetes Management: A Review of Diet, Exercise, and Natural Products.
abstract: Diabetes mellitus (DM) is a highly prevalent condition that causes significant morbidity and mortality in the United States and worldwide. Conventional therapies include lifestyle modification, oral pharmacological agents, and subcutaneous insulin. Emerging data suggest that natural approaches to the treatment of DM may help supplement current therapies for further glycemic control. Herein, we review the evidence of several natural modalities for DM treatment. We describe the pathophysiology of diabetes and its complications, provide an overview of current pharmacologic treatments, and finally, discuss natural approaches to diabetes management. Specifically, we will describe on the utility of diet, physical activity, and common natural products in the treatment of DM and focus on recent, high-quality studies. Adverse effects and potential interactions of each therapy will be highlighted where applicable.
authors.affiliation: Division of Medicine, Emory University School of Medicine, Atlanta, GA, United States.
authors.forename: William M
authors.initials: WM
authors.lastname: Schultz
authors.affiliation: Division of Medicine, Emory University School of Medicine, Atlanta, GA, United States.
authors.forename: Tina
authors.initials: T
authors.lastname: Varghese
authors.affiliation: Division of Medicine, Emory University School of Medicine, Atlanta, GA, United States.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Heinl
authors.affiliation: Division of Medicine, Emory University School of Medicine, Atlanta, GA, United States.
authors.forename: Devinder S
authors.initials: DS
authors.lastname: Dhindsa
authors.affiliation: Division of Medicine, Emory University School of Medicine, Atlanta, GA, United States.
authors.forename: Elliot N
authors.initials: EN
authors.lastname: Mahlof
authors.affiliation: Emory University, Atlanta, GA, United States.
authors.forename: Hannah C
authors.initials: HC
authors.lastname: Cai
authors.affiliation: Division of Medicine, Emory University School of Medicine, Atlanta, GA, United States.
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Southmayd
authors.affiliation: Division of Medicine, Emory University School of Medicine, Atlanta, GA, United States.
authors.forename: Pratik B
authors.initials: PB
authors.lastname: Sandesara
authors.affiliation: Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, United States.
authors.forename: Danny J
authors.initials: DJ
authors.lastname: Eapen
authors.affiliation: Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, United States.
authors.forename: Laurence S
authors.initials: LS
authors.lastname: Sperling
mesh_terms: D000818:Animals; D001688:Biological Products / Q000008:administration & dosage / Q000627:therapeutic use*; D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000503:physiopathology; D004032:Diet; D015444:Exercise; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D001688:Biological Products; D007004:Hypoglycemic Agents
keywords: Diabetes mellitus; diet; herbal supplements; interval training; natural; pharmacological agents.