title: Construction of a non-enzymatic sensor based on the poly(o-phenylenediamine)/Ag-NPs composites for detecting glucose in blood.
abstract: A non-enzymatic glucose sensor, based on the silver nanoparticles (Ag-NPs)/poly (o-phenylenediamine) (PoPD) composites, is developed by the electrochemical polymerization of o-phenylenediamine and electrodeposition of silver nanoparticles on an indium tin oxide electrode. The Ag-NPs/PoPD composites are characterized by atomic force microscopy, scanning electronic microscopy and energy dispersive spectrometer. Under the optimized experimental conditions, the proposed glucose sensor demonstrates a wide linear range from 0.15 to 13mmolL-1with a correlation coefficient of 0.998. The proposed glucose sensor can be used to detect glucose in blood sample with a satisfactory result. In addition, the proposed sensor presents the advantages, such as facile preparation, low cost, high sensitivity and fast response time. It also exhibits good anti-interference performance and stability.
authors.affiliation: College of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Environmental Engineering and Monitoring, Yangzhou University, 180 Si-Wang-Ting Road, Yangzhou 225002, China.
authors.forename: Jinxiang
authors.initials: J
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Environmental Engineering and Monitoring, Yangzhou University, 180 Si-Wang-Ting Road, Yangzhou 225002, China.
authors.forename: Meirong
authors.initials: M
authors.lastname: Wang
authors.affiliation: Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, Yangzhou 225002, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Guan
authors.affiliation: College of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Environmental Engineering and Monitoring, Yangzhou University, 180 Si-Wang-Ting Road, Yangzhou 225002, China. Electronic address: wangcy@yzu.edu.cn.
authors.forename: Chengyin
authors.initials: C
authors.lastname: Wang
authors.affiliation: School of Mathematical and Physical Sciences, University of Technology Sydney, City Campus, Broadway, Sydney, NSW 2007, Australia.
authors.forename: Guoxiu
authors.initials: G
authors.lastname: Wang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D001786:Blood Glucose / Q000032:analysis*; D002138:Calibration; D004566:Electrodes; D004595:Electroplating; D006801:Humans; D006863:Hydrogen-Ion Concentration; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010084:Oxidation-Reduction; D010655:Phenylenediamines / Q000737:chemistry*; D058105:Polymerization; D015203:Reproducibility of Results; D012834:Silver / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D017971:Tin Compounds / Q000737:chemistry
chemical_list: D001786:Blood Glucose; D010655:Phenylenediamines; D017971:Tin Compounds; C530487:poly(o-phenylenediamine); D012834:Silver; C109984:indium tin oxide
keywords: Blood; Electrochemical sensor; Glucose; Silver nanoparticles; o-Phenylenediamine