title: RETRACTED: Salidroside alleviates cigarette smoke-induced COPD in mice.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
  
  This article has been retracted at the request of the authors, who have informed the Editor-in-Chief that they had not obtained the necessary ethical approval for the animal studies before performing the experiments. It is the policy of the journal that all animal experiments should comply with the ARRIVE guidelines and should be carried out in accordance with the U.K. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010/63/EU for animal experiments, or the National Research Council's Guide for the Care and Use of Laboratory Animals.
  
  The authors have also informed the editors that the results of the IL-1β ELISA are not reliable due to issues with the reagents.
  
  Concern was also raised about the reliability of the Western blot results in Figure 5, which appear to contain suspected similarities between the P-P38 and Iκ Bα blots, as detailed here: https://pubpeer.com/publications/C87E1CABF28D49C30B80A05DF2C3DB#1. The journal requested the corresponding author comment on these concerns and provide the raw data. The journal did not receive a response to this request.
authors.affiliation: Department of Physiology and Pharmacology, China Pharmaceutical University, Nanjing, China.
authors.forename: Fen
authors.initials: F
authors.lastname: Luo
authors.affiliation: Department of Physiology and Pharmacology, China Pharmaceutical University, Nanjing, China.
authors.forename: Jingyan
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Physiology and Pharmacology, China Pharmaceutical University, Nanjing, China. Electronic address: yantianhuabest@126.com.
authors.forename: Tianhua
authors.initials: T
authors.lastname: Yan
authors.affiliation: Department of Physiology and Pharmacology, China Pharmaceutical University, Nanjing, China. Electronic address: miaomingxingcpu@126.com.
authors.forename: Mingxing
authors.initials: M
authors.lastname: Miao
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005960:Glucosides / Q000494:pharmacology / Q000627:therapeutic use*; D008168:Lung / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D016328:NF-kappa B / Q000037:antagonists & inhibitors / Q000378:metabolism; D010636:Phenols / Q000494:pharmacology / Q000627:therapeutic use*; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D011897:Random Allocation; D012907:Smoking / Q000009:adverse effects*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000378:metabolism
chemical_list: D005960:Glucosides; D016328:NF-kappa B; D010636:Phenols; D014409:Tumor Necrosis Factor-alpha; C009172:rhodioloside
keywords: COPD; Inflammation; Salidroside