title: Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits.
abstract: Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. The technique of ultrasound microbubbles is safe, controllable, nonimmunogenic, and repeatable. It provides us with a novel idea in the administration of neuroprotective drugs.
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen, Guangdong Province, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Shen
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen, Guangdong Province, China; School of Ophthalmology & Optometry Affiliated to Shenzhen University, Shenzhen, Guangdong, China.
authors.forename: Lina
authors.identifier: 0000-0002-5733-5413
authors.initials: L
authors.lastname: Huang
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen, Guangdong Province, China.
authors.forename: Dahui
authors.initials: D
authors.lastname: Ma
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen, Guangdong Province, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xie
authors.affiliation: Shenzhen People's Hospital, Shenzhen, Guangdong, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Li
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China.
authors.forename: Aineng
authors.initials: A
authors.lastname: Zeng
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen, Guangdong Province, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Zeng
authors.affiliation: Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, China; Shenzhen Key Laboratory of Ophthalmology, Shenzhen, Guangdong Province, China.
authors.forename: Ruyin
authors.initials: R
authors.lastname: Tian
authors.affiliation: Shenzhen University, Shenzhen, Guangdong, China.
authors.forename: Tianfu
authors.initials: T
authors.lastname: Wang
authors.affiliation: Shenzhen University, Shenzhen, Guangdong, China.
authors.forename: Siping
authors.initials: S
authors.lastname: Chen