title: A pilot study to assess the morphology and progression of non-carious cervical lesions.
abstract: OBJECTIVE
  This longitudinal pilot study aimed to morphologically and quantitatively investigate the progress of non-carious cervical lesions (NCCLs) by using swept-source optical coherence tomography (SS-OCT).
  
  
  METHODS
  The samples examined comprised sets of NCCL epoxy resin replicas obtained from 10 lesions in 6 patients who attended annual dental visits over 4 or 5 years. SS-OCT images of the replicas were analyzed in terms of the maximum depth (Dmax) and corresponding vertical width (VW) - using an image analyzer to estimate progression of the NCCLs over time.
  
  
  RESULTS
  It was found that differences between wedge- and saucer-shaped lesions were morphologically distinguished well by the OCT images. There were significant differences in dimensions among Dmax, VW and horizontal width (HW). HW was the largest and Dmaxwas the smallest. Although no significant differences in absolute values of annual progression rates were found among Dmax,VW and HW, the percentage increase in Dmaxwas significantly greater compared to VW and HW. The ratios of Dmaxto corresponding VW ranged from 0.49 to 1.01 for the wedge-shaped lesions and from 0.13 to 0.44 for saucer-shaped lesions, respectively.
  
  
  CONCLUSIONS
  The dimensional analysis demonstrated notable progression with large variations. The wedge-shaped lesions appeared to show greater Dmaxvalues compared to the saucer-shaped lesions.
  
  
  CONCLUSIONS
  With respect to the depth, the wedge-shaped lesions may progress at a greater rate compared to the saucer-shaped lesions.
authors.affiliation: Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
authors.forename: Iori
authors.initials: I
authors.lastname: Sugita
authors.affiliation: Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
authors.forename: Syozi
authors.initials: S
authors.lastname: Nakashima
authors.affiliation: Clinical Oral Science, Department of Oral Health Care Sciences, Faculty of Dentistry, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-0034, Japan.
authors.forename: Asaomi
authors.initials: A
authors.lastname: Ikeda
authors.affiliation: Department of Biomaterials, Melbourne Dental School, University of Melbourne, 720 Swanston St, Victoria, 3010, Australia.
authors.forename: Michael F
authors.initials: MF
authors.lastname: Burrow
authors.affiliation: Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Nikaido
authors.affiliation: Medical Education Development Center, Nagasaki University Hospital, Nagasaki, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan. Electronic address: kubo@nagasaki-u.ac.jp.
authors.forename: Shisei
authors.initials: S
authors.lastname: Kubo
authors.affiliation: Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
authors.forename: Junji
authors.initials: J
authors.lastname: Tagami
authors.affiliation: Division of Oral and Dental Surgery, Department of Advanced Medicine, National Hospital for Geriatric Medicine, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi 474-8511, Japan.
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Sumi
mesh_terms: D000293:Adolescent; D000328:Adult; D003768:Dental Occlusion, Centric; D003793:Dental Restoration, Permanent; D003799:Dental Stress Analysis; D004853:Epoxy Resins / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007564:Japan; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods; D014072:Tooth Abrasion / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D019237:Tooth Cervix / Q000000981:diagnostic imaging* / Q000473:pathology*; D057085:Tooth Wear / Q000000981:diagnostic imaging* / Q000473:pathology*; D055815:Young Adult
chemical_list: D004853:Epoxy Resins
keywords: Longitudinal study; Morphology; Non-carious cervical lesion; Progression; Swept-source optical coherence tomography