title: Fingerprint changes among cancer patients treated with paclitaxel.
abstract: BACKGROUND
  Fingerprints have long been used for personal identification; however, some case reports suggested that some chemotherapy agents such as paclitaxel lead to fingerprints loss due to hand-and-foot syndrome (HFS).
  
  
  METHODS
  This case-control study was performed on 65 patients who received chemotherapy regimens with/without paclitaxel. Patients with the history of receiving any drugs with significant HFS adverse effect or patients with any conditions that affect fingerprints were excluded. Baseline and post-chemotherapy images of fingerprint examples were referred to the Iranian Society of Legal Medicine to compare changes in the fingerprints.
  
  
  RESULTS
  Thirty-one patients entered in the paclitaxel and 34 subjects in the control groups. Seventeen patients (54.8%) in the paclitaxel group experienced fingerprint changes, whereas no patient had fingerprint changes in the control group. By physical examination, no patients in the two groups experienced HFS. After adjusting for age, sex, occupation, and cancer type, there was a significant difference between the two groups regarding fingerprint changes (P = 0.002, OR 13.69, 95% CI 2.05 to infinite).
  
  
  CONCLUSIONS
  Considering that fingerprint recognition has been utilized in both government and civilian investigation, patients taking paclitaxel and centers necessitating fingerprint identification should be informed about possible fingerprint changes by paclitaxel.
authors.affiliation: Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Payam
authors.initials: P
authors.lastname: Azadeh
authors.affiliation: Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Simin
authors.initials: S
authors.lastname: Dashti-Khavidaki
authors.affiliation: Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Ali Yaghobi
authors.initials: AY
authors.lastname: Joybari
authors.affiliation: Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Samaneh
authors.initials: S
authors.lastname: Sarbaz
authors.affiliation: Faculty of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
authors.forename: Atefeh
authors.initials: A
authors.lastname: Jafari
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Yaseri
authors.affiliation: Department of Forensic Medicine and Medical Toxicology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Afshin
authors.initials: A
authors.lastname: Amini
authors.affiliation: Endocrine Research Center, Institute of Endocrinology and Metabolism, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran. maryfarasati@gmail.com.
authors.forename: Maryam
authors.initials: M
authors.lastname: Farasatinasab
mesh_terms: D016022:Case-Control Studies; D003878:Dermatoglyphics; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D017239:Paclitaxel / Q000627:therapeutic use*
chemical_list: D017239:Paclitaxel
keywords: Fingerprint changes; Fingerprint recognition; Hand-and-foot syndrome (HFS); Paclitaxel