title: Chronic vulvovaginal candidiasis in patients using a levonorgestrel-containing intrauterine device.
abstract: Chronic vulvovaginal candidiasis is usually responsive to therapy with oral antifungals. We present a case series of 13 patients with this condition who were also using a levonorgestrel intrauterine system (LNG-IUS). All cases responded to ongoing oral fluconazole therapy while the LNG-IUS was in situ. The LNG-IUS was removed in six patients and of these, two experienced clinical improvement with lower fluconazole dosage requirements and three experienced complete resolution of symptoms. One remains on fluconazole 100 mg daily.
authors.affiliation: Department of Dermatology, Kolling Institute, Northern Sydney Local Health District, Sydney, New South Wales, Australia.|Department of Dermatology, Royal North Shore Hospital, Sydney, New South Wales, Australia.|Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Nguyen
authors.affiliation: Department of Dermatology, Kolling Institute, Northern Sydney Local Health District, Sydney, New South Wales, Australia.|Department of Dermatology, Royal North Shore Hospital, Sydney, New South Wales, Australia.|Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Gayle
authors.initials: G
authors.lastname: Fischer
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy* / Q000209:etiology; D002908:Chronic Disease; D003271:Contraceptive Agents, Female; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D007436:Intrauterine Devices, Medicated / Q000009:adverse effects*; D016912:Levonorgestrel; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000935:Antifungal Agents; D003271:Contraceptive Agents, Female; D016912:Levonorgestrel; D015725:Fluconazole
keywords: chronic vulvovaginal candidiasis; intrauterine device; levonorgestrel intrauterine device; levonorgestrel intrauterine system; recurrent vulvovaginal candidiasis