title: LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering.
abstract: To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay.
  
  
  
  R package LEAP available on CRAN.
  
  
  
  jun.li@nd.edu.
  
  
  
  Supplementary data are available at Bioinformatics online.
authors.forename: Alicia T
authors.initials: AT
authors.lastname: Specht
authors.forename: Jun
authors.initials: J
authors.lastname: Li
mesh_terms: D000465:Algorithms; D000818:Animals; D019295:Computational Biology / Q000379:methods; D003713:Dendritic Cells / Q000378:metabolism; D015870:Gene Expression; D020869:Gene Expression Profiling / Q000379:methods*; D053263:Gene Regulatory Networks; D051379:Mice; D012313:RNA; D017423:Sequence Analysis, RNA / Q000379:methods*; D059010:Single-Cell Analysis / Q000379:methods*; D012984:Software
chemical_list: D012313:RNA