title: Organocatalytic Enantioselective Continuous-Flow Cyclopropanation.
abstract: A set of six solid-supported diarylprolinol catalysts (varying on the anchoring strategy and the type of polymeric support) has been prepared and applied to the enantioselective cyclopropanation reaction. The selected candidate allows implementation of a long flow experiment (48 h) and generates a library of 12 cyclopropanes by sequential flow experiments. The mildness and utility of the method have enabled a telescoped process in which the outstream is directly used in a Wittig flow reaction.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans, 16, 43007 Tarragona, Spain.
authors.forename: Patricia
authors.initials: P
authors.lastname: Llanes
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans, 16, 43007 Tarragona, Spain.
authors.forename: Carles
authors.identifier: 0000-0001-8159-416X
authors.initials: C
authors.lastname: Rodríguez-Escrich
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans, 16, 43007 Tarragona, Spain.
authors.forename: Sonia
authors.initials: S
authors.lastname: Sayalero
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans, 16, 43007 Tarragona, Spain.|Departament de Química Inorgànica i Orgànica, Universitat de Barcelona (UB) , 08028 Barcelona, Spain.
authors.forename: Miquel A
authors.identifier: 0000-0003-0195-8846
authors.initials: MA
authors.lastname: Pericàs