title: Can Low Level Laser Therapy Benefit Bone Regeneration in Localized Maxillary Cystic Defects? - A Prospective Randomized Control Trial.
abstract: OBJECTIVE
  The aim of the study was to evaluate the effect of Low-Level Laser Therapy (LLLT) on bone formation in cystic defects following cyst enucleation.
  
  
  METHODS
  The sample was composed of sixteen patients with enucleated maxillary bony cystic lesions. With an age range from 20 - 44 grouped as eight Laser and eight Control patients. Laser group was subjected to low intensity diode laser immediately after surgery and then for three times per week for two weeks using a therapeutic laser irradiation. Group B (control group): patients were not subjected laser therapy.
  
  
  RESULTS
  The predictor variable was exposure of bone defect to LLLT or none. The outcome variable was bone density changes measured by digital radiographs at day 1 and days 90 postoperatively. Descriptive and bivariate statistics were computed. There were no statistically significant differences between the 2 groups for the bone density at day 1. There was a statistically significant difference in bone density changes in each group at day 90: Significant at P ≤ 0.05. After adjusting for differences in day 1 for bone density, the estimated mean change in bone density changes at day 90 was significantly larger for Laser compared with control.
  
  
  CONCLUSIONS
  The results of this study suggested that LLLT can enhance bone healing in maxillary cystic defects. This can serve as an adjunct method in preventing possible delayed healing and pathological fractures This also will be helpful for more researchers in early loading in case of dental implants to accelerate osseointegration.
authors.affiliation: National Institute of Laser Enhanced Sciences, Cairo University, Cairo, Egypt.
authors.forename: Ahmed Abbas
authors.initials: AA
authors.lastname: Zaky
authors.affiliation: Surgery and Oral Medicine Department, National Research Center, Cairo, Egypt.
authors.forename: Hanaa Mohamed Mohamed
authors.initials: HM
authors.lastname: El Shenawy
authors.affiliation: National Institute of Laser Enhanced Sciences, Cairo University, Cairo, Egypt.
authors.forename: Tarek Abdel Hamed
authors.initials: TA
authors.lastname: Harhsh
authors.affiliation: Oral Surgery and Medicine Department, National Research Center, Cairo, Egypt.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Shalash
authors.affiliation: Oral Surgery and Medicine Department, National Research Center, Cairo, Egypt.
authors.forename: Noha Mohamed Ismael
authors.initials: NM
authors.lastname: Awad
keywords: LLLT; cystic lesion; digital radiograph; low intensity pulsed ultrasound