title: Biosensors of bacterial cells.
abstract: Biosensors are devices which utilize both an electrical component (transducer) and a biological component to study an environment. They are typically used to examine biological structures, organisms and processes. The field of biosensors has now become so large and varied that the technology can often seem impenetrable. Yet the principles which underlie the technology are uncomplicated, even if the details of the mechanisms are elusive. In this review we confine our analysis to relatively current advancements in biosensors for the detection of whole bacterial cells. This includes biosensors which rely on an added labeled component and biosensors which do not have a labeled component and instead detect the binding event or bound structure on the transducer. Methods to concentrate the bacteria prior to biosensor analysis are also described. The variety of biosensor types and their actual and potential uses are described.
authors.affiliation: Department of Pharmaceutical and Administrative Science, Concordia University School of Pharmacy, 12800 N. Lake Shore Dr., Mequon, WI 53097, United States. Electronic address: Robert.burlage@cuw.edu.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Burlage
authors.affiliation: Department of Pharmaceutical and Administrative Science, Concordia University School of Pharmacy, 12800 N. Lake Shore Dr., Mequon, WI 53097, United States.
authors.forename: Joshua
authors.initials: J
authors.lastname: Tillmann
mesh_terms: D001419:Bacteria / Q000302:isolation & purification*; D015374:Biosensing Techniques / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods; D007158:Immunologic Techniques / Q000379:methods; D058185:Magnetite Nanoparticles / Q000032:analysis / Q000737:chemistry
chemical_list: D058185:Magnetite Nanoparticles
keywords: Antibody; Bacteria; Biosensor; Detection; Immunomagnetic separation; Transducer