title: Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?
abstract: We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex. Due to the severity of her IPAH, an upfront triple combination therapy, including i.v. epoprostenol, was started. The rapid institution of this treatment regimen allowed a complete right ventricular reverse remodelling after 1 year of therapy, leading to a down-titration until complete suspension of epoprostenol from the treatment regimen.
authors.affiliation: Department of Health Science, Pulmonology Unit, University of Milan Bicocca, San Gerardo Hospital, Monza, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Paciocco
authors.affiliation: Department of Health Science, Pulmonology Unit, University of Milan Bicocca, San Gerardo Hospital, Monza, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Lombi
authors.affiliation: Department of Health Science, Cardiology Unit, San Gerardo Hospital, Monza, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Vincenzi
authors.affiliation: Department of Health Science, Pulmonology Unit, University of Milan Bicocca, San Gerardo Hospital, Monza, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Pesci
authors.affiliation: Department of Health Science, Cardiology Unit, San Gerardo Hospital, Monza, Italy.
authors.forename: Felice
authors.initials: F
authors.lastname: Achilli
keywords: Idiopathic pulmonary arterial hypertension; Pregnancy; Right ventricular failure; Right ventricular remodelling; Triple combination therapy