title: Does stroke etiology play a role in predicting outcome of acute stroke patients who underwent endovascular treatment with stent retrievers?
abstract: OBJECTIVE
  The goal of the study was to identify whether the stroke etiology play a role in the recanalization and outcome of patients who underwent mechanical thrombectomy with stent retrievers.
  
  
  RESULTS
  A retrospective analysis of a prospectively collected database included consecutive patients treated with stent retrievers. We included patients with cardioembolic stroke and large vessel atherosclerotic disease and compared risk factors for stroke, baseline NIHSS and Alberta Stroke Program Early CT scores (ASPECTS), stroke outcome, recanalization rate, onset-to-recanalization, onset-to-groin puncture time and the procedural time between two groups. Male sex was statistically more common in patients with large vessel atherosclerotic disease. Mean time from symptom onset- to the achievement of recanalization in patients with LVAD was 242±72.4 compared with cardioembolic stroke patients (301±70.7; p=0.014). Time for groin puncture to recanalization was longer in patients with cardioembolic stroke compared to LVAD group (97.5±44.3 vs 58.2±21.8; p=0.002). Time for microcatheter to successful recanalization or procedural termination was longer in patients with cardioembolic stroke compared to LVAD group (63.6±30.2 vs 34.2±19.4; p<0.001) with cardioembolic stroke had significantly worse long-term outcome (mRS 3-6) compared to those with LVAD (60.6% vs 26.3%; p=0.036).
  
  
  CONCLUSIONS
  Stroke etiology may play a role in the outcome of acute stroke patients who underwent endovascular stroke therapy. Cardioembolic strokes may be more resistant to endovascular acute stroke treatment.
authors.affiliation: Gaziantep University, Medical Faculty, Department of Neurology, Interventional Neurology, Turkey. Electronic address: sgiray72@hotmail.com.
authors.forename: Semih
authors.initials: S
authors.lastname: Giray
authors.affiliation: Eskisehir Osmangazi University, Medical Faculty, Department of Neurology, Neurocritical Care, Cerebrovascular Disease, Interventional Neurology, Eskisehir, Turkey. Electronic address: atillaozcanozdemir@gmail.com.
authors.forename: Ozcan
authors.initials: O
authors.lastname: Ozdemir
authors.affiliation: Eskisehir Osmangazi University, Medical Faculty, Department of Neurology, Neurocritical Care, Cerebrovascular Disease, Interventional Neurology 26040 Eskisehir, Turkey. Electronic address: demetf@gmail.com.
authors.forename: Demet F
authors.initials: DF
authors.lastname: Baş
authors.affiliation: Gaziantep University, Medical Faculty, Department of Neurology, Turkey. Electronic address: yusufinanc77@hotmail.com.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: İnanç
authors.affiliation: Baskent University, Medical Faculty, Department of Neurology, Ankara, Turkey. Electronic address: zarlier@gmail.com.
authors.forename: Zulfikar
authors.initials: Z
authors.lastname: Arlıer
authors.affiliation: Harran University, Medical Faculty, Department of Neurology, Turkey. Electronic address: ozcankocaturk@gmail.com.
authors.forename: Ozcan
authors.initials: O
authors.lastname: Kocaturk
mesh_terms: D002545:Brain Ischemia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D002318:Cardiovascular Diseases / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D002533:Cerebral Angiography; D057510:Endovascular Procedures; D005260:Female; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D020766:Intracranial Embolism / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D015607:Stents; D020521:Stroke / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D017131:Thrombectomy; D061665:Time-to-Treatment; D016896:Treatment Outcome
keywords: Endovascular; Etiology; Outcome; Stent retriever; Stroke