title: Capecitabine-Induced Severe Toxicity Secondary to DPD Deficiency and Successful Treatment with Low Dose 5-Fluorouracil.
authors.affiliation: Department of Medical Oncology, Leiden University Medical Center, P.O. Box 9600, Post zone C7-P, 2300 RC, Leiden, The Netherlands.
authors.forename: Catc
authors.initials: C
authors.lastname: Lunenburg
authors.affiliation: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Swen
authors.affiliation: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: H-J
authors.initials: HJ
authors.lastname: Guchelaar
authors.affiliation: Department of Medical Oncology, Leiden University Medical Center, P.O. Box 9600, Post zone C7-P, 2300 RC, Leiden, The Netherlands. A.J.Gelderblom@lumc.nl.
authors.forename: H
authors.initials: H
authors.lastname: Gelderblom
mesh_terms: D000069287:Capecitabine / Q000009:adverse effects* / Q000493:pharmacokinetics; D054067:Dihydropyrimidine Dehydrogenase Deficiency / Q000175:diagnosis / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000069287:Capecitabine; D005472:Fluorouracil