title: Iron oxide nanoparticle surface decorated with cRGD peptides for magnetic resonance imaging of brain tumors.
abstract: In this article, a specific targeting Magnetic Resonance Imaging (MRI) nanoplatform, composed by iron oxide nanoparticle (NP) with cRGD peptides as targeting agent onto NP surface, is explored for the diagnosis of brain tumors by MRI using intracranial U87MG mice xenograft tumor. This article is part of a Special Issue entitled "Recent Advances in Bionanomaterials" Guest Editor: Dr. Marie-Louise Saboungi and Dr. Samuel D. Bader.
authors.affiliation: Laboratoire Matière et Systèmes Complexes (MSC), UMR 7057, CNRS and Université Paris Diderot, 75205 Paris Cedex 05, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Richard
authors.affiliation: Unité d'Imagerie par Résonance Magnétique et de Spectroscopie, CEA/DRF/I2BM/NeuroSpin, F-91191, Gif-sur-Yvette, France.
authors.forename: Marianne
authors.initials: M
authors.lastname: Boucher
authors.affiliation: Service de Médecine Nucléaire, Hôpital Avicenne Assistance Publique-Hôpitaux de Paris, F-93009 Bobigny, France; Inserm, U1148, Laboratory for Vascular Translational Science, UFR SMBH, Université Paris 13, Sorbonne Paris Cité, F-93017 Bobigny, France.
authors.forename: Yoann
authors.initials: Y
authors.lastname: Lalatonne
authors.affiliation: Unité d'Imagerie par Résonance Magnétique et de Spectroscopie, CEA/DRF/I2BM/NeuroSpin, F-91191, Gif-sur-Yvette, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Mériaux
authors.affiliation: Inserm, U1148, Laboratory for Vascular Translational Science, UFR SMBH, Université Paris 13, Sorbonne Paris Cité, F-93017 Bobigny, France. Electronic address: laurence.motte@univ-paris13.fr.
authors.forename: Laurence
authors.initials: L
authors.lastname: Motte
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D045744:Cell Line, Tumor; D003287:Contrast Media / Q000737:chemistry* / Q000378:metabolism; D005290:Ferric Compounds / Q000737:chemistry* / Q000378:metabolism; D005909:Glioblastoma / Q000737:chemistry* / Q000378:metabolism; D064593:Heterografts; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008297:Male; D051379:Mice; D008819:Mice, Nude; D050997:Nanomedicine / Q000379:methods*; D009842:Oligopeptides / Q000737:chemistry* / Q000378:metabolism; D011237:Predictive Value of Tests; D013499:Surface Properties
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; D009842:Oligopeptides; C000499:ferric oxide; C047981:arginyl-glycyl-aspartic acid
keywords: Glioblastoma; Iron oxide nanoparticle; MRI contrast agent; Targeting; cRGD