title: [Arginase Level in Apheresis Leukocyte-Reduced Platelets Stored for Different Time].
abstract: OBJECTIVE
  To explore the effect of storage time on arginase level and possible source of arginase in apheresis leukocyte-reduced platelets(ALR-Plt).
  
  
  METHODS
  The arginase level and myeloperoxidase(MPO) levels in ALR-Plt and control plasma were detected by ELISA. The relationship between arginase level and MPO level in ALR-Plt was analyzed by correlation analysis.
  
  
  RESULTS
  There was no significant difference of arginase level between ALR-Plt stored less than 3 days and control plasma. However, arginase level in ALR-Plt stored over 3 days was significantly higher than that in ALR-Plt stored less than 3 days and control plasma(P<0.05). There was no significant difference of MPO level in ALR-Plt stored for different times, but the MPO level in ALR-Plt stored for different time was lower than that in control plasma. Correlation analysis showed that arginase level positively correlated with MPO level in ALR-Plt of different storage time (r=0.58).
  
  
  CONCLUSIONS
  The arginase level in ALR-Plt stored over 3 days increase significantly. The main possible source of arginase in ALR-Plt is the residual white blood cells, especially neutrophils.
authors.affiliation: Department of Blood Transfusion, The Union Hospital, Fujian Medical University,Fujian Institute of Hematology, Fuzhou 350001, Fujian Province, China.
authors.forename: Hao-Bo
authors.initials: HB
authors.lastname: Huang
authors.affiliation: Department of Blood Transfusion, The Union Hospital, Fujian Medical University,Fujian Institute of Hematology, Fuzhou 350001, Fujian Province, China.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Fan
authors.affiliation: Department of Blood Transfusion, The Union Hospital, Fujian Medical University,Fujian Institute of Hematology, Fuzhou 350001, Fujian Province, China.
authors.forename: Shi-Jin
authors.initials: SJ
authors.lastname: Wei
authors.affiliation: Department of Blood Transfusion, Department of Hematology, The Union Hospital, Fujian Medical University,Fujian Institute of Hematology, Fuzhou 350001, Fujian Province, China. E-mail: fudanhui@189.cn.
authors.forename: Dan-Hui
authors.initials: DH
authors.lastname: Fu
authors.affiliation: Department of Blood Transfusion, The Union Hospital, Fujian Medical University,Fujian Institute of Hematology, Fuzhou 350001, Fujian Province, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zeng
authors.affiliation: Department of Blood Transfusion, The Union Hospital, Fujian Medical University,Fujian Institute of Hematology, Fuzhou 350001, Fujian Province, China.
authors.forename: Qing-Hua
authors.initials: QH
authors.lastname: Huang
mesh_terms: D001119:Arginase; D001792:Blood Platelets; D001793:Blood Preservation; D006801:Humans; D007962:Leukocytes; D009195:Peroxidase; D010949:Plasma; D010983:Plateletpheresis
chemical_list: D009195:Peroxidase; D001119:Arginase