title: Acute fluoxetine treatment increases aggressiveness in juvenile matrinxã (Brycon amazonicus).
abstract: Fluoxetine (FLX) is a selective serotonin (5-HT) reuptake inhibitor known for its effects modifying aggressiveness, personality traits, and anxiety-like behaviors. The aim of the present study was to evaluate the influence of the acute treatment, by immersion, with FLX on aggressive behavior of resident Brycon amazonicus fish. Fish pretreated with FLX presented an increase in aggressiveness, evidenced by the increase on the number of bites and chases against the intruder and a decrease in latency for the first attack, when compared to control fish. Together with previous studies, these results show the complexity of the neural modulation of the aggressive behavior in fish by 5-HTergic system.
authors.affiliation: Departamento de Morfologia e Fisiologia Animal, Faculdade de Ciências agrárias e Veterinárias/Centro de Aquicultura (CAUNESP), Universidade Estadual Paulista, UNESP, Jaboticabal, SP, Brazil. carlawolkers@yahoo.com.br.|Faculdade de Ciências Integradas do Pontal (FACIP), Universidade Federal de Uberlândia, UFU, Ituiutaba, MG, Brazil. carlawolkers@yahoo.com.br.
authors.forename: Carla Patricia Bejo
authors.initials: CPB
authors.lastname: Wolkers
authors.affiliation: Departamento de Morfologia e Fisiologia Animal, Faculdade de Ciências agrárias e Veterinárias/Centro de Aquicultura (CAUNESP), Universidade Estadual Paulista, UNESP, Jaboticabal, SP, Brazil.
authors.forename: Mônica
authors.initials: M
authors.lastname: Serra
authors.affiliation: Departamento de Ciência e Tecnologia, Secretaria de Ciência, Tecnologia e Insumos Estratégicos do Ministério da Saúde (DECIT/SCTIE/MS), Brasilia, DF, Brazil.
authors.forename: Augusto
authors.initials: A
authors.lastname: Barbosa Júnior
authors.affiliation: Departamento de Morfologia e Fisiologia Animal, Faculdade de Ciências agrárias e Veterinárias/Centro de Aquicultura (CAUNESP), Universidade Estadual Paulista, UNESP, Jaboticabal, SP, Brazil.
authors.forename: Elisabeth Criscuolo
authors.initials: EC
authors.lastname: Urbinati
mesh_terms: D000374:Aggression / Q000187:drug effects*; D000375:Aging; D000818:Animals; D018687:Antidepressive Agents, Second-Generation / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects*; D060125:Characiformes / Q000502:physiology*; D005473:Fluoxetine / Q000494:pharmacology*
chemical_list: D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine
keywords: Aggressive behavior; Fish; Fluoxetine; Serotonin