title: ent-Labdane Diterpenoids from Dodonaea viscosa.
abstract: Seven new and two known ent-labdane diterpenoids have been isolated from a single plant specimen of Dodonaea viscosa ssp. spatulata, found in Tasmania, Australia. Prior to this study, only seven different labdane diterpenoids had been isolated from D. viscosa. The structures of the natural products were assigned via 1D and 2D NMR spectroscopy and other standard spectroscopic methods. The absolute configuration of three ent-labdane diterpenoids was determined by single-crystal X-ray crystallography of synthetic derivatives. Significantly, the results of this study suggest that the absolute configuration of some known labdane diterpenoids may have been misassigned.
authors.affiliation: School of Physical Sciences-Chemistry and ‡Central Science Laboratory, University of Tasmania , Hobart, Tasmania, Australia.
authors.forename: Wesley J
authors.initials: WJ
authors.lastname: Olivier
authors.affiliation: School of Physical Sciences-Chemistry and ‡Central Science Laboratory, University of Tasmania , Hobart, Tasmania, Australia.
authors.forename: Nathan L
authors.initials: NL
authors.lastname: Kilah
authors.affiliation: School of Physical Sciences-Chemistry and ‡Central Science Laboratory, University of Tasmania , Hobart, Tasmania, Australia.
authors.forename: James
authors.initials: J
authors.lastname: Horne
authors.affiliation: School of Physical Sciences-Chemistry and ‡Central Science Laboratory, University of Tasmania , Hobart, Tasmania, Australia.
authors.forename: Alex C
authors.identifier: http://orcid.org/0000-0001-5515-2878
authors.initials: AC
authors.lastname: Bissember
authors.affiliation: School of Physical Sciences-Chemistry and ‡Central Science Laboratory, University of Tasmania , Hobart, Tasmania, Australia.
authors.forename: Jason A
authors.identifier: http://orcid.org/0000-0001-6313-3298
authors.initials: JA
authors.lastname: Smith
mesh_terms: D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D029631:Sapindaceae / Q000737:chemistry*; D013648:Tasmania
chemical_list: D004224:Diterpenes