title: Treatment outcome in patients with presumed tubercular uveitis at a tertiary referral eye care centre in Singapore.
abstract: OBJECTIVE
  To report the clinical features and outcome of patients with presumed tubercular uveitis (TBU).
  
  
  METHODS
  Retrospective analysis of patients with presumed TBU at a tertiary referral eye care centre in Singapore between 2007 and 2012 was done. Main outcome measures were failure of complete resolution of uveitis or recurrence of inflammation.
  
  
  RESULTS
  Fifty three patients with mean age of 44.18 ± 15.26 years with 54.72% being males were included. 19 (35.85%) had bilateral involvement, with panuveitis and anterior uveitis being the most common presentations. 36 (67.92%) patients received antitubercular therapy (ATT), and 28 received concurrent systemic steroids. 15 (28.30%) eyes of 11 (30.55%) patients in the ATT group and 4 (21.05%) eyes of 3 (17.64%) patients in the non-ATT group had treatment failure (p value = 0.51).
  
  
  CONCLUSIONS
  The use of ATT, with or without concurrent corticosteroid, may not have a statistically significant impact in improving treatment success in patients with presumed TBU.
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, 308433, Singapore.
authors.forename: Leslie
authors.initials: L
authors.lastname: Ang
authors.affiliation: Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
authors.forename: Aera
authors.initials: A
authors.lastname: Kee
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, 308433, Singapore.
authors.forename: Tun Hang
authors.initials: TH
authors.lastname: Yeo
authors.affiliation: Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore.
authors.forename: V G
authors.initials: VG
authors.lastname: Dinesh
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, 308433, Singapore.
authors.forename: Su Ling
authors.initials: SL
authors.lastname: Ho
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, 308433, Singapore.|Eagle Eye Centre, Singapore, Singapore.
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Teoh
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, 308433, Singapore. rupesh_agrawal@ttsh.com.sg.
authors.forename: Rupesh
authors.initials: R
authors.lastname: Agrawal
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015864:Panuveitis / Q000188:drug therapy; D012008:Recurrence; D012189:Retrospective Studies; D012846:Singapore; D062606:Tertiary Care Centers / Q000706:statistics & numerical data; D016896:Treatment Outcome; D014392:Tuberculosis, Ocular / Q000188:drug therapy*; D014605:Uveitis / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D000995:Antitubercular Agents
keywords: Antitubercular therapy; Panuveitis; Steroids; Tubercular uveitis; Tuberculosis