title: Secondary cvd prevention-Lipid modification strategies: A critical analysis.
abstract: Lipid modification holds the key to effective secondary prevention of cardiovascular disease (CVD). However there is a controversy on whether it's all about targeting specific lipid sub fractions to a particular level or a direct effect of the agent(s) used or both. This review intends to look into these important issues from an evidence-based perspective. What is the appropriate timing of testing for lipid profile after a cardiovascular event? What is the rationale behind initiating with a high dose statin after an acute coronary event? What is the role of targeting lipid sub fractions beside LDL cholesterol? Is there any role for non-statin based therapy after an acute cardiovascular event? What constitutes a long-term lipid modification strategy in patients post CVD? These are very important questions, which needs to be addressed adequately as well as scientifically. The secondary CVD preventive strategies form a lipid perspective, which requires a thorough review.
authors.affiliation: Nightingale Hospital, 11 Shakespeare Sarani, Kolkata, India. Electronic address: ramdasghosal@gmail.com.
authors.forename: Samit
authors.initials: S
authors.lastname: Ghosal
authors.affiliation: AMRI Hospitals, JC-16/17, Salt Lake City, Kolkata 700091, India.
authors.forename: Binayak
authors.initials: B
authors.lastname: Sinha
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood / Q000517:prevention & control*; D006801:Humans; D008055:Lipids / Q000097:blood*
chemical_list: D008055:Lipids
keywords: Cardiovascular disease; Fibrates; HDL cholesterol; Inflammation; LDL cholesterol; Lipids; Secondary prevention; Statins; Triglyceride