title: MPF, a multipurpose figure of merit for phasing procedures.
abstract: The efficient multipurpose figure of merit MPF has been defined and characterized. It may be very helpful in phasing procedures. Indeed, it might be used for establishing the centric or acentric nature of an unknown structure, for identifying the presence of some pseudotranslational symmetry, for recognizing the correct solution in multisolution approaches and for estimating the quality of structure models as they become available during the phasing process. Thus, phase improvement or deterioration may be monitored and useless models may be discarded to save computing time. It is also shown that MPF may be applied in different phasing approaches, no matter if ab initio or non ab initio.
authors.affiliation: Istituto di Cristallografia, CNR, Via G. Amendola 122/o, Bari, I-70126, Italy.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Burla
authors.affiliation: Istituto di Cristallografia, CNR, Via G. Amendola 122/o, Bari, I-70126, Italy.
authors.forename: Benedetta
authors.initials: B
authors.lastname: Carrozzini
authors.affiliation: Istituto di Cristallografia, CNR, Via G. Amendola 122/o, Bari, I-70126, Italy.
authors.forename: Giovanni Luca
authors.initials: GL
authors.lastname: Cascarano
authors.affiliation: Istituto di Cristallografia, CNR, Via G. Amendola 122/o, Bari, I-70126, Italy.
authors.forename: Carmelo
authors.initials: C
authors.lastname: Giacovazzo
authors.affiliation: Istituto di Cristallografia, CNR, Via G. Amendola 122/o, Bari, I-70126, Italy.
authors.forename: Giampiero
authors.initials: G
authors.lastname: Polidori
mesh_terms: D018360:Crystallography, X-Ray; D008961:Models, Structural
keywords: direct methods; figure of merit; phase refinement; phasing