title: Evidence-Based Medicine: Options for Dupuytren's Contracture: Incise, Excise, and Dissolve.
abstract: OBJECTIVE
  After studying this article, the participant should be able to: 1. Understand updates in the basic science, epidemiology, and treatment of Dupuytren's disease. 2. Understand treatment with needle aponeurotomy, collagenase, and fasciectomy. 3. Understand advanced needle techniques for Dupuytren's contracture. 4. Understand the safety and effectiveness of a new treatment, collagenase.
  
  
  CONCLUSIONS
  The literature on Dupuytren's disease encompasses many specialties. Its treatment is generally by perforating, excising, or dissolving the affected tissues. This article reviews the changing understanding of this disease and treatment options.
authors.affiliation: San Francisco, Calif.|From the Division of Plastic Surgery, University of California, San Francisco.
authors.forename: Keith A
authors.initials: KA
authors.lastname: Denkler
authors.affiliation: San Francisco, Calif.|From the Division of Plastic Surgery, University of California, San Francisco.
authors.forename: Carolyn J
authors.initials: CJ
authors.lastname: Vaughn
authors.affiliation: San Francisco, Calif.|From the Division of Plastic Surgery, University of California, San Francisco.
authors.forename: Estelle L
authors.initials: EL
authors.lastname: Dolan
authors.affiliation: San Francisco, Calif.|From the Division of Plastic Surgery, University of California, San Francisco.
authors.forename: Scott L
authors.initials: SL
authors.lastname: Hansen
mesh_terms: D000368:Aged; D017364:Collagenases / Q000008:administration & dosage; D004387:Dupuytren Contracture / Q000628:therapy*; D019317:Evidence-Based Medicine; D000071938:Fasciotomy / Q000379:methods; D006801:Humans; D008875:Middle Aged; D012008:Recurrence; D013629:Tamoxifen / Q000008:administration & dosage; D014143:Traction; D014221:Triamcinolone / Q000008:administration & dosage
chemical_list: D013629:Tamoxifen; D014221:Triamcinolone; D017364:Collagenases