title: Lupus cystitis presenting with hidronephrosis and gastrointestinal involvement.
abstract: BACKGROUND
  Lupus cystitis is a rare manifestation of systemic lupus erythematosus, characterized by thickening of the bladder wall, associated with ureterohydronephrosis. In several cases gastrointestinal symptoms are the main manifestation. The optimal immunosuppressive regimen is still unknown.
  
  
  METHODS
  16-year-old girl with systemic lupus erythematosus was admitted with dysuria, renal impairment, diarrhea, abdominal pain, nausea and vomiting. An abdominal CT scan demonstrated moderate bilateral dilation from the pelvis to the ureterovesical junction, and the bladder exhibited reduced capacity and diffusely thickened walls. A diagnosis of chronic interstitial cystitis was performed and treatment with high dose methylprednisolone resulted in a significant relief of gastrointestinal and urinary symptoms and a reduction of the bladder thickness with improvement of their capacity.
  
  
  CONCLUSIONS
  Lupus cystitis is a rare and underdiagnosed urinary manifestation of LES and the presence of mild urinary symptoms and abdominal pain may alert about this possibility.
authors.affiliation: Universidade Federal de Alagoas, Brazil.
authors.forename: Flávio
authors.initials: F
authors.lastname: Teles
authors.affiliation: Santa Casa de Misericórdia de Maceió, Brazil.
authors.forename: Larissa Gonçalves de Albuquerque
authors.initials: LG
authors.lastname: Santos
authors.affiliation: Universidade Federal de Alagoas, Brazil.
authors.forename: Carlos Eugênio Lira
authors.initials: CE
authors.lastname: Tenório
authors.affiliation: Santa Casa de Misericórdia de Maceió, Brazil.
authors.forename: Monique Ramalho
authors.initials: MR
authors.lastname: Marinho
authors.affiliation: Santa Casa de Misericórdia de Maceió, Brazil.
authors.forename: Saulo Rodrigo de Ramalho
authors.initials: SR
authors.lastname: Moraes
authors.affiliation: Santa Casa de Misericórdia de Maceió, Brazil.
authors.forename: Davi de Brito
authors.initials: DB
authors.lastname: Câmara
authors.affiliation: Universidade Estadual de Ciências da Saúde de Alagoas, Brazil.
authors.forename: Renata Oliveira
authors.initials: RO
authors.lastname: Santos
authors.affiliation: Universidade Estadual de Ciências da Saúde de Alagoas, Brazil.
authors.forename: Camila Ricardo Uchôa
authors.initials: CR
authors.lastname: Lins
authors.affiliation: Universidade Estadual de Ciências da Saúde de Alagoas, Brazil.
authors.forename: André Falcão Pedrosa
authors.initials: AF
authors.lastname: Costa
mesh_terms: D000293:Adolescent; D003556:Cystitis / Q000150:complications*; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology*; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*