title: Implementation of Rapid Molecular Infectious Disease Diagnostics: the Role of Diagnostic and Antimicrobial Stewardship.
abstract: New rapid molecular diagnostic technologies for infectious diseases enable expedited accurate microbiological diagnoses. However, diagnostic stewardship and antimicrobial stewardship are necessary to ensure that these technologies conserve, rather than consume, additional health care resources and optimally affect patient care. Diagnostic stewardship is needed to implement appropriate tests for the clinical setting and to direct testing toward appropriate patients. Antimicrobial stewardship is needed to ensure prompt appropriate clinical action to translate faster diagnostic test results in the laboratory into improved outcomes at the bedside. This minireview outlines the roles of diagnostic stewardship and antimicrobial stewardship in the implementation of rapid molecular infectious disease diagnostics.
authors.affiliation: Section of Hospital Medicine, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA kevin.messacar@childrenscolorado.org.|Section of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Messacar
authors.affiliation: Section of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Parker
authors.affiliation: Section of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: James K
authors.initials: JK
authors.lastname: Todd
authors.affiliation: Section of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: Samuel R
authors.initials: SR
authors.lastname: Dominguez
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003141:Communicable Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D004363:Drug Utilization / Q000592:standards*; D042241:Early Diagnosis; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D013997:Time Factors
chemical_list: D000890:Anti-Infective Agents
keywords: antimicrobial stewardship; appropriate use criteria; diagnostic stewardship; implementation; rapid diagnostics; utilization