title: Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies.
abstract: OBJECTIVE
  We aimed to evaluate the diagnostic accuracy and safety of computed tomography (CT)-guided biopsy of pulmonary lesions with fine needle aspiration (FNA) using non-coaxial technique.
  
  
  METHODS
  We analyzed 442 patients who underwent CT-guided lung biopsy with FNA and non-coaxial technique to determine the diagnostic outcomes, complication rates, and independent risk factors for diagnostic failure and pneumothorax.
  
  
  RESULTS
  Diagnostic accuracy, sensitivity, and specificity were 97.6%, 97.3%, and 100%, respectively. Age and >35 mm lesion size were significant risk factors for diagnostic failure. The rates of pneumothorax and chest tube placement were 19% and 2.9%, respectively. Middle and lower lobe location, lesion to pleura distance >7.5 mm, and >45° needle trajectory angle were significant risk factors for pneumothorax.
  
  
  CONCLUSIONS
  CT-guided FNA of pulmonary lesions with non-coaxial technique is a safe and reliable method with a relatively low pneumothorax rate and an acceptably high diagnostic accuracy.
authors.affiliation: Department of Radiology, Ankara University School of Medicine, Ankara, Turkey. cuzun77@yahoo.com.
authors.forename: Çağlar
authors.initials: Ç
authors.lastname: Uzun
authors.forename: Zehra
authors.initials: Z
authors.lastname: Akkaya
authors.forename: Ebru
authors.initials: E
authors.lastname: Düşünceli Atman
authors.forename: Evren
authors.initials: E
authors.lastname: Üstüner
authors.forename: Elif
authors.initials: E
authors.lastname: Peker
authors.forename: Başak
authors.initials: B
authors.lastname: Gülpınar
authors.forename: Atilla Halil
authors.initials: AH
authors.lastname: Elhan
authors.forename: Koray
authors.initials: K
authors.lastname: Ceyhan
authors.forename: Kayhan Çetin
authors.initials: KÇ
authors.lastname: Atasoy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D015505:Chest Tubes / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011030:Pneumothorax / Q000453:epidemiology*; D015641:Radiography, Interventional / Q000379:methods; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult