title: Central tegmentum tract hyperintensities in pediatric neurological patients: Incidence or coincidence.
abstract: OBJECTIVE
  The central tegmental tract hyperintensities (CTTH) have been found in many different pediatric neurological conditions. There is only scarce data about the value of this radiological phenomenon. In this study we aimed to show the neurological conditions associated with this radiological finding.
  
  
  METHODS
  We performed a retrospective analysis of all pediatric brain MRI's between 2013 and 2015. After finding those patients with CTTH, we evaluated them in the pediatric neurology clinic.
  
  
  RESULTS
  There were 41 out of 1464 brain MRI's with CTTH with 2.8% prevalence. Thirty four patients (23 male, age range 3months-98months) were available for evaluation. CTTH were present in mainly younger age group. There were many different neurological conditions associated with CTTH. These included brain tumors, epilepsy, developmental delay, metabolic disorders and genetic syndromes.
  
  
  CONCLUSIONS
  CTTH is found in many different pediatric neurological conditions. Further neuropathological and prospective MRI and clinical studies are needed to better understand this interesting radiological finding.
authors.affiliation: Acıbadem University, Department of Pediatrics, Division of Pediatric Neurology, Kozyatağı Acıbadem Hastanesi, İnönü Cad. Okur Sok. No: 20, Kozyatağı, Istanbul, Turkey. Electronic address: ugur.isik@acibadem.com.tr.
authors.forename: Uğur
authors.initials: U
authors.lastname: Işık
authors.affiliation: Acıbadem University, Department of Radiology, Kozyatağı Acıbadem Hastanesi, İnönü Cad. Okur Sok. No: 20, Kozyatağı, Istanbul, Turkey. Electronic address: alp.dincer@acibadem.com.tr.
authors.forename: Alp
authors.initials: A
authors.lastname: Dinçer
mesh_terms: D000293:Adolescent; D001928:Brain Diseases, Metabolic / Q000000981:diagnostic imaging / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D004827:Epilepsy / Q000000981:diagnostic imaging / Q000453:epidemiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D009422:Nervous System Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D065821:Pontine Tegmentum / Q000000981:diagnostic imaging*; D015995:Prevalence
keywords: Central tegmentum tract hyperintensity; Children; Epilepsy; Genetic syndromes; Metabolic disorders