title: Clinical value of MRI-detected extramural venous invasion in rectal cancer.
abstract: Extramural venous invasion (EMVI) is associated with a poor prognosis and a poor overall survival rate in rectal cancer. It can independently predict local and distant tumor recurrences. Preoperative EMVI detection in rectal cancer is useful for determining the treatment strategy. EMVI status is beneficial for the post-treatment evaluation and analysis of rectal cancer. Magnetic resonance imaging (MRI) is a non-invasive diagnostic modality with no radiation effects. High-resolution MRI can detect EMVI with high accuracy. In addition, MRI results are equal to or even better than pathological results in the detection of medium to large EMVI in rectal cancer. MRI-detected EMVI (mrEMVI) can be used as a potential biomarker that facilitates treatment methods. This review highlights the importance of MRI before and after rectal cancer treatment. In addition, we analyze the prognostic correlation between mrEMVI and circulating tumor cells (CTC) in rectal cancer. This article may help shed light on the significance of mrEMVI.
authors.affiliation: Department of Radiology, Zhongshan Hospital and Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai Institute of Medical Imaging, Shanghai, China.
authors.forename: Pratik
authors.initials: P
authors.lastname: Tripathi
authors.affiliation: Department of Radiology, Zhongshan Hospital and Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai Institute of Medical Imaging, Shanghai, China.
authors.forename: Sheng Xiang
authors.initials: SX
authors.lastname: Rao
authors.affiliation: Department of Radiology, Zhongshan Hospital and Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai Institute of Medical Imaging, Shanghai, China.
authors.forename: Meng Su
authors.initials: MS
authors.lastname: Zeng
mesh_terms: D001808:Blood Vessels / Q000000981:diagnostic imaging / Q000473:pathology*; D059248:Chemoradiotherapy / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009361:Neoplasm Invasiveness / Q000000981:diagnostic imaging; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011379:Prognosis; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D012008:Recurrence
keywords: circulating tumor cells; extramural venous invasion; magnetic resonance imaging; rectal cancer