title: Microbiological Assessment ofMoringa OleiferaExtracts and Its Incorporation in Novel Dental Remedies against Some Oral Pathogens.
abstract: OBJECTIVE
  To assess the antibacterial and antifungal potentials of different parts ofMoringa oleiferaplant using different extraction methods in attempts to formulate natural dental remedies from this plant.
  
  
  METHODS
  Three solvents extracts (Ethanol, acetone, and ethyl acetate) of different parts of Egyptian Moringa tree were prepared and tested against oral pathogens:Staphylococcus aureus,Streptococcus mutans, andCandida albicansusing disc diffusion method; As well as to incorporate the plant extract to formulate experimental toothpaste and mouthwash. The two dental remedies were assessed against the same microbial strains. Statistical analysis was performed using One-Way ANOVA test to compare the inhibition zone diameter and t-test.
  
  
  RESULTS
  Ethanol extracts as well as leaves extracts demonstrated the highest significant mean inhibition zone values (P ≤ 0.05) againstStaphylococcus aureusandStreptococcus mutansgrowth. However, all extracts revealed no inhibition zone againstCandida albicans. For dental remedies, experimental toothpaste exhibited higher mean inhibition than the mouthwash againstStaphylococcus aureus,Streptococcus mutansand only the toothpaste revealed antifungal effect againstCandida albicans.
  
  
  CONCLUSIONS
  The different extracts of different parts of Moringa showed an antibacterial effect againstStaphylococcus aureusandStreptococcus mutansgrowth. The novel toothpaste of ethanolic leaves extract has antimicrobial and antifungal potential effects all selected strains.
authors.affiliation: National Research Centre, Restorative Dentistry and Dental Material Research Department, Giza, Egypt.
authors.forename: Hanaa
authors.initials: H
authors.lastname: Elgamily
authors.affiliation: National Research Centre, Prosthodontics, Giza, Egypt.
authors.forename: Amani
authors.initials: A
authors.lastname: Moussa
authors.affiliation: National Research Centre, Prosthodontics, Giza, Egypt.
authors.forename: Asmaa
authors.initials: A
authors.lastname: Elboraey
authors.affiliation: National Research Centre, Dairy Science Department (Microbiology Lab.), Food Industries and Nutrition Division, Giza, Egypt.
authors.forename: Hoda
authors.initials: H
authors.lastname: El-Sayed
authors.affiliation: National Research Centre, Dairy Science Department (Microbiology Lab.), Food Industries and Nutrition Division, Giza, Egypt.
authors.forename: Marwa
authors.initials: M
authors.lastname: Al-Moghazy
authors.affiliation: National Research Centre, Technology of Horticulture Crops Department, Agriculture Research Division, Giza, Egypt.
authors.forename: Aboelfetoh
authors.initials: A
authors.lastname: Abdalla
keywords: (Novel Dental Remedies); Antimicrobial Activity; Moringa extract; Novel experimental tooth paste; mouth wash