title: Re-emergent tremor in Parkinson's disease: Clinical and accelerometric properties.
abstract: Re-emergent tremor (RET) and the classical parkinsonian rest tremor were considered as two different phenomena of the same central tremor circuit. However, clinical and accelerometric characteristics of these tremors were not previously compared in a single study. We evaluated disease characteristics and accelerometric measurements of two tremor types in 42 patients with Parkinson's disease. Disease specific features and accelerometric measurements of peak frequency, amplitude at peak frequency and the root mean square (RMS) amplitude of two tremor types were compared. Eighteen patients had RET and the mean latency of the RET was 9.48 (±9.2)s. Groups of only rest tremor and RET did not differ significantly in age of disease onset, disease duration and severity and mean levodopa equivalent dose. Comparison of peak frequency and amplitude at peak frequency were not different between the groups, but RMS amplitude was significantly higher in the RET group (p=0.03). RMS amplitude of RET was also correlated with disease severity (r=.48, p=0.04). These results support the previous notion that rest tremor and RET are analogue, both are triggered by the same central ossilator with RET being only the suppression of the rest tremor due to arm repositioning.
authors.affiliation: Turgut Özal University, Faculty of Medicine, Department of Neurology, Ankara, Turkey. Electronic address: zubeydeayturk@yahoo.com.
authors.forename: Zübeyde
authors.initials: Z
authors.lastname: Aytürk
authors.affiliation: Department of Neurodegeneration, Hertie Institute for Clinical Brain Research (HIH), University of Tuebingen, Tuebingen, Germany. Electronic address: rezzak.yilmaz@uni-tuebingen.de.
authors.forename: Rezzak
authors.initials: R
authors.lastname: Yilmaz
authors.affiliation: Ankara University, School of Medicine, Department of Neurology, Ankara, Turkey. Electronic address: Cenk.Akbostanci@medicine.ankara.edu.tr.
authors.forename: M Cenk
authors.initials: MC
authors.lastname: Akbostanci
mesh_terms: D000368:Aged; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis* / Q000188:drug therapy; D056888:Patient Positioning; D012146:Rest; D014202:Tremor / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa
keywords: Parkinson’s disease; Re-emergent tremor; Tremor