title: Minimally invasive endoscopic treatment for pediatric combined high grade stenosis as a laryngeal manifestation of epidermolysis bullosa.
abstract: Epidermolysis bullosa refers to a clinically and genetically heterogeneous group of inherited mucocutaneous diseases. Laryngotracheal lesions are momentous regarding the risk of sudden airway obstruction. The traditional treatment is tracheostomy. This case report highlights the advantages of minimally invasive interventions. A successful combined endoscopic management of a life-threatening respiratory crisis is presented in a 4-year-old child. Combined commissure stenosis with supraglottic spread was treated by CO2laser dissection and bilateral endoscopic arytenoid abduction lateropexy, supplemented with mitomycin C application. Due to expectable less scarring, the combination of these modern methods may be an efficient solution in these vulnerable respiratory tracts.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Hungary. Electronic address: palinkodora@gmail.com.
authors.forename: Dora
authors.initials: D
authors.lastname: Palinko
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Hungary.
authors.forename: Vera
authors.initials: V
authors.lastname: Matievics
authors.affiliation: Department of Anaesthesiology and Intensive Therapy, University of Szeged, Hungary.
authors.forename: Ilona
authors.initials: I
authors.lastname: Szegesdi
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Hungary.
authors.forename: Balazs
authors.initials: B
authors.lastname: Sztano
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Szeged, Hungary.
authors.forename: Laszlo
authors.initials: L
authors.lastname: Rovo
mesh_terms: D000477:Alkylating Agents / Q000008:administration & dosage; D001193:Arytenoid Cartilage / Q000601:surgery; D002425:Cautery / Q000295:instrumentation; D002675:Child, Preschool; D004820:Epidermolysis Bullosa / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007828:Laryngoscopy / Q000379:methods*; D007829:Laryngostenosis / Q000175:diagnosis / Q000601:surgery*; D007830:Larynx / Q000473:pathology / Q000601:surgery; D054020:Lasers, Gas / Q000627:therapeutic use*; D019060:Minimally Invasive Surgical Procedures; D016685:Mitomycin / Q000008:administration & dosage; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin
keywords: Arytenoid abduction lateropexy; CO(2) laser; Commissure stenosis; Epidermolysis bullosa; Minimally invasive laryngo-microsurgery; Pediatric airway stenosis