title: Blood discard rate in a blood center in Curitiba - Brazil. Ten years of study.
abstract: BACKGROUND
  Development of technologies to reduce transfusion risks of infectious diseases is a major characteristic of hemotherapy. Thus, each donation undergoes clinical and serological screening tests to ensure the donated blood do not offer risks to the receiver.
  
  
  OBJECTIVE
  Evaluate the prevalence of positive serology in blood donations rejected by Hemobanco (Curitiba - PR) in the period ranging from January 2003 to December 2012.
  
  
  METHODS
  During the period studied, we observed the total number of donations and its division according to gender. We also analyzed the number of rejected donations due to seropositivity, considering the diseases investigated routinely in blood banks in Brazil, and the frequency of discards according to age groups.
  
  
  RESULTS
  Within the period studied, 399,280 donations were performed. 62.0% donors were male. Comparing 2003 to 2012, we noticed a significant decrease of discards, from 10.2% to 5.0%, respectively. There was a reduction of seropositivity for HIV, HBsAg and anti-HBc and an increase for Chagas Disease, hepatitis C, syphilis and HTLV. The age group with the highest prevalence for discards changed: it used to be the 40-59 years old group in 2003, and became the 20-39 years old group in 2012.
  
  
  CONCLUSIONS
  There was an increase in the number of donations in Hemobanco and a decrease in total discards due to seropositive donations. Most donors were male. The most prevalent cause of discards only amongst seropositive donation discards is seropositivity for anti-HBc. There was a significant increase of donors aged between 20 and 39 years old.
authors.affiliation: Departamento de Medicina, Faculdade Evangélica do Paraná, Curitiba, Paraná, Brazil.
authors.forename: Aline G
authors.initials: AG
authors.lastname: Monich
authors.affiliation: Departamento de Medicina, Faculdade Evangélica do Paraná, Curitiba, Paraná, Brazil.
authors.forename: Tiago W
authors.initials: TW
authors.lastname: Dantas
authors.affiliation: Instituto Paranaense de Hemoterapia e Hematologia Ltda, Curitiba, Paraná, Brazil.
authors.forename: Karla B
authors.initials: KB
authors.lastname: Fávero
authors.affiliation: Instituto Paranaense de Hemoterapia e Hematologia Ltda, Curitiba, Paraná, Brazil.
authors.forename: Paulo T R
authors.initials: PTR
authors.lastname: Almeida
authors.affiliation: Departamento de Medicina, Universidade Positivo, Curitiba, Paraná, Brazil.
authors.forename: Eliane C
authors.initials: EC
authors.lastname: Maluf
authors.affiliation: Departamento de Medicina, Faculdade Evangélica do Paraná, Curitiba, Paraná, Brazil.
authors.forename: Carolina De M
authors.initials: CM
authors.lastname: Capeletto
authors.affiliation: Departamento de Medicina, Faculdade Evangélica do Paraná, Curitiba, Paraná, Brazil; Departamento de Medicina, Universidade Positivo, Curitiba, Paraná, Brazil. Electronic address: renatomitsu@yahoo.com.br.
authors.forename: Renato M
authors.initials: RM
authors.lastname: Nisihara
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001771:Blood Banks; D001782:Blood Donors; D001938:Brazil / Q000453:epidemiology; D014355:Chagas Disease / Q000097:blood / Q000453:epidemiology; D046148:Donor Selection; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000453:epidemiology; D015490:HTLV-I Infections / Q000097:blood / Q000453:epidemiology; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology; D006526:Hepatitis C / Q000097:blood / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013587:Syphilis / Q000097:blood / Q000201:enzymology
keywords: Blood bank; Blood donors; Serologic tests