title: The changes of electrolytes in serum and urine in children with neurally mediated syncope cured by oral rehydration salts.
abstract: OBJECTIVE
  To detect the changes of electrolytes in serum and urine in children with nerve mediated syncope (NMS) cured by oral rehydration salts (ORS).
  
  
  METHODS
  From May 2014 to April 2015, 135 patients with symptoms like unexplained syncope and presyncope were administrated in our hospital, including 60 boys and 75 girls, aged between 4 and 16 (10.2±2.7) years. After head-up tilt test (HUTT), their electrolytes in serum and urine were examined. Those who were positive to the HUTT received ORS and health education, while others were only treated by health education. With the period of subsequent visit arranging 21-154 (42.6±27.7) days, the improvement of their clinical manifestation were inquired and electrolytes in serum and urine were re-tested.
  
  
  RESULTS
  (1) The total effective percentage of ORS treatment was 63.0%, and the negative conversion rate of HUTT was 48.2%. (2) In the first time of visit to hospital, there was no statistical significance between the HUTT-positive and the HUTT- negative in serum electrolytes, 24-h urine electrolytes and 24-h urine volume (P>0.05). (3) In the return visit to hospital, the serum calcium and serum phosphorus in the HUTT-positive were higher than those in the HUTT-negative (P<0.05). (4) With the intake of ORS, 24-h urine sodium, 24-h urine chlorine and 24-h urine volume were improved than pre-treatment (P<0.05 or 0.01).
  
  
  CONCLUSIONS
  ORS was an effective treatment to the NMS children, with 24-h urine volume and urine chloride increasing.
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China; Department of Pediatrics, The Third Hospital of Changsha, Changsha, Hunan 410015, China.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China.
authors.forename: Runmei
authors.initials: R
authors.lastname: Zou
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China.
authors.forename: Lijia
authors.initials: L
authors.lastname: Wu
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Luo
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xu
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Lin
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China.
authors.forename: Zhenwu
authors.initials: Z
authors.lastname: Xie
authors.affiliation: Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University/Institute of Pediatrics, Central South University, Changsha, Hunan 410011, China. Electronic address: wangcheng2nd@126.com.
authors.forename: Cheng
authors.initials: C
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D004562:Electrocardiography; D004573:Electrolytes / Q000097:blood* / Q000652:urine*; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012492:Salts / Q000494:pharmacology*; D013575:Syncope / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D004573:Electrolytes; D012492:Salts
keywords: 24-h urine electrolyte; Child; Neurally mediated syncope; Oral rehydration salts; Serum electrolyte