title: [Hemorrhagic syndrome during cobimetinib therapy: The need for caution in patients receiving new anticoagulant drugs].
authors.affiliation: Service de dermatologie, hôpital Saint-Vincent-de-Paul, boulevard de Belfort, 59000 Lille, France; Université catholique, 60, boulevard Vauban, 59800 Lille, France. Electronic address: aurore.leguern@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Le Guern
authors.affiliation: Service de dermatologie, hôpital Saint-Vincent-de-Paul, boulevard de Belfort, 59000 Lille, France; Université catholique, 60, boulevard Vauban, 59800 Lille, France.
authors.forename: D
authors.initials: D
authors.lastname: Lebas
authors.affiliation: Centre de pharmacovigilance, CHRU, 1, place de Verdun, 59045 Lille cedex, France.
authors.forename: E-M
authors.initials: EM
authors.lastname: Thillard
authors.affiliation: Service de dermatologie, hôpital Saint-Vincent-de-Paul, boulevard de Belfort, 59000 Lille, France.
authors.forename: C
authors.initials: C
authors.lastname: Martincic
authors.affiliation: Service de dermatologie, hôpital Saint-Vincent-de-Paul, boulevard de Belfort, 59000 Lille, France.
authors.forename: T
authors.initials: T
authors.lastname: Wiart
authors.affiliation: Service de dermatologie, hôpital Saint-Vincent-de-Paul, boulevard de Belfort, 59000 Lille, France; Université catholique, 60, boulevard Vauban, 59800 Lille, France.
authors.forename: P
authors.initials: P
authors.lastname: Modiano
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D001384:Azetidines / Q000009:adverse effects*; D004347:Drug Interactions; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008297:Male; D010880:Piperidines / Q000009:adverse effects*; D011720:Pyrazoles / Q000627:therapeutic use*; D011728:Pyridones / Q000627:therapeutic use*; D013577:Syndrome
chemical_list: D000925:Anticoagulants; D001384:Azetidines; D010880:Piperidines; D011720:Pyrazoles; D011728:Pyridones; C522181:apixaban; C574276:cobimetinib