title: Systematic review and meta-analysis of single-incision versus conventional multiport laparoscopic splenectomy.
abstract: BACKGROUND
  There is no consensus that single-incision laparoscopic surgery splenectomy (SILS-SP) is on a par with conventional multiport laparoscopic surgery splenectomy (CMLS-SP).
  
  
  OBJECTIVE
  The aim of this systematic review and meta-analysis was to assess feasibility and safety of SILS-SP when compared with CMLS-SP.
  
  
  METHODS
  Eligible articles were identified by searching several databases including PubMed, EMBASE, CNKI (China) and the Cochrane Library, up until February 2016. Studies were reviewed independently and rated by Newcastle-Ottawa Quality Assessment Scale. Evaluated outcomes were complications, operative time, post-operative hospital stay, blood loss, starting diet, post-operative pain scores, conversion and analgesic requirements.
  
  
  RESULTS
  Ten retrospective studies met the eligibility criteria. Overall, there was no significant difference between SILS-SP and CMLS-SP in complications, operative time, post-operative hospital stay, blood loss, starting diet, post-operative pain scores, conversion and analgesic requirements.
  
  
  CONCLUSIONS
  SILS-SP is feasible and safe in certain patients, with no obvious advantages over CMLS-SP. Therefore, it may be considered an alternative to CMLS-SP. We await high-quality, double-blind RCTs. These should include clear statements on standard scores of post-operative pain and cosmetic results, longer follow-up assessment and cost-benefit analysis.
authors.affiliation: Department of Gastrointestinal and Anal Surgery, Rui Kang Hospital, Guangxi Traditional Chinese Medical University, Nanning 530001, Guangxi Zhuang Autonomous Region; Department of Gastrointestinal Surgery, Affiliated Tumor Hospital of Guangxi Medical University Nanning 530021, Guangxi Autonomous Region, China.
authors.forename: Shike
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Gastrointestinal Surgery, Affiliated Tumor Hospital of Guangxi Medical University Nanning 530021, Guangxi Autonomous Region, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Lai
authors.affiliation: Department of Clinical Laboratory, Children's Hospital, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning 530003, Guangxi, China.
authors.forename: Jiangyang
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Department of Gastrointestinal and Anal Surgery, Rui Kang Hospital, Guangxi Traditional Chinese Medical University, Nanning 530001, Guangxi Zhuang Autonomous Region, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Deng
authors.affiliation: Department of Gastrointestinal and Anal Surgery, Rui Kang Hospital, Guangxi Traditional Chinese Medical University, Nanning 530001, Guangxi Zhuang Autonomous Region, China.
authors.forename: Jianbao
authors.initials: J
authors.lastname: Wei
authors.affiliation: Department of Gastrointestinal and Anal Surgery, Rui Kang Hospital, Guangxi Traditional Chinese Medical University, Nanning 530001, Guangxi Zhuang Autonomous Region, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Liang
authors.affiliation: Department of Gastrointestinal Surgery, Affiliated Tumor Hospital of Guangxi Medical University Nanning 530021, Guangxi Autonomous Region, China.
authors.forename: Xianwei
authors.initials: X
authors.lastname: Mo
authors.affiliation: Department of Gastrointestinal Surgery, Affiliated Tumor Hospital of Guangxi Medical University Nanning 530021, Guangxi Autonomous Region, China.
authors.forename: Jiansi
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Gastrointestinal Surgery, Affiliated Tumor Hospital of Guangxi Medical University Nanning 530021, Guangxi Autonomous Region, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Lin