title: Use of Precision Medicine Molecular Profiling of Baseline Tumor Specimen May Not Benefit Outcomes in Children With Relapsed or Refractory Pediatric Sarcomas.
authors.affiliation: Section of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: J
authors.initials: J
authors.lastname: Carter
authors.affiliation: Section of Medical and Molecular Genetics, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: L
authors.initials: L
authors.lastname: Cheng
authors.affiliation: Section of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: J
authors.initials: J
authors.lastname: Zucker
authors.affiliation: Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: M
authors.initials: M
authors.lastname: Marshall
authors.affiliation: Section of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: K
authors.initials: K
authors.lastname: Pollok
authors.affiliation: Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: M
authors.initials: M
authors.lastname: Murray
authors.affiliation: Section of Medical and Molecular Genetics, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.affiliation: Section of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
authors.forename: J
authors.initials: J
authors.lastname: Renbarger
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D056970:Co-Repressor Proteins / Q000235:genetics; D004264:DNA Topoisomerases, Type I; D019008:Drug Resistance, Neoplasm; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D025202:Molecular Diagnostic Techniques / Q000379:methods; D058990:Molecular Targeted Therapy / Q000379:methods / Q000706:statistics & numerical data; D000071185:Pharmacogenomic Testing / Q000379:methods; D010865:Pilot Projects; D011379:Prognosis; D012509:Sarcoma / Q000188:drug therapy / Q000235:genetics / Q000401:mortality / Q000473:pathology; D055502:Secondary Prevention / Q000379:methods*; D016896:Treatment Outcome; D014404:Tubulin / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; D056970:Co-Repressor Proteins; C570667:TLE3 protein, human; C498585:TUBB3 protein, human; D014404:Tubulin; D004264:DNA Topoisomerases, Type I; C528909:TOP1 protein, human