title: Development of a first-generation miniature multiple reference optical coherence tomography imaging device.
abstract: Multiple reference optical coherence tomography (MR-OCT) is a technology ideally suited to low-cost, compact OCT imaging. This modality is an extension of time-domain OCT with the addition of a partial mirror in front of the reference mirror. This enables extended, simultaneous depth scanning with the relatively short scan range of a miniature voice coil motor on which the scanning mirror is mounted. This work details early stage development of the first iteration of a miniature MR-OCT device. This iteration utilizes a fiber-coupled input from an off-board superluminescent diode. The dimensions of the module are 40 × 57 ?? mm . Off-the-shelf miniature optical components, voice coil motors, and photodetectors are used, with the complexity of design depending on the specific application. The photonic module can be configured as either polarized or nonpolarized and can include balanced detection. The results shown in this work are from the nonpolarized device. The system was characterized through measurement of the input spectrum, axial resolution, and signal-to-noise ratio. Typical B-scans of static and in vivo samples are shown, which illustrate the potential applications for such a technology.
authors.affiliation: National University of Ireland, School of Physics, Tissue Optics and Microcirculation Imaging Group, National Biophotonics and Imaging Platform, Galway H91 CF50, IrelandbCompact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States.
authors.forename: Paul M
authors.initials: PM
authors.lastname: McNamara
authors.affiliation: National University of Ireland, School of Physics, Tissue Optics and Microcirculation Imaging Group, National Biophotonics and Imaging Platform, Galway H91 CF50, IrelandbCompact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States.
authors.forename: Roshan
authors.initials: R
authors.lastname: Dsouza
authors.affiliation: Irish Photonic Integration Centre (IPIC), Tyndall National Institute, Lee Maltings Complex, Dyke Parade, Cork T12 R5CP, Ireland.
authors.forename: Colm
authors.initials: C
authors.lastname: O'Riordan
authors.affiliation: Irish Photonic Integration Centre (IPIC), Tyndall National Institute, Lee Maltings Complex, Dyke Parade, Cork T12 R5CP, Ireland.
authors.forename: Seán
authors.initials: S
authors.lastname: Collins
authors.affiliation: Irish Photonic Integration Centre (IPIC), Tyndall National Institute, Lee Maltings Complex, Dyke Parade, Cork T12 R5CP, Ireland.
authors.forename: Peter
authors.initials: P
authors.lastname: O'Brien
authors.affiliation: Compact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States.
authors.forename: Carol
authors.initials: C
authors.lastname: Wilson
authors.affiliation: Compact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States.
authors.forename: Josh
authors.initials: J
authors.lastname: Hogan
authors.affiliation: National University of Ireland, School of Physics, Tissue Optics and Microcirculation Imaging Group, National Biophotonics and Imaging Platform, Galway H91 CF50, Ireland.
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Leahy
mesh_terms: D020405:Dermis / Q000000981:diagnostic imaging; D004817:Epidermis / Q000000981:diagnostic imaging; D004867:Equipment Design; D005385:Fingers / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods*