title: Antioxidant Activities and Chemical Constituents of Flavonoids from the Flower of Paeonia ostii.
abstract: Paeonia ostiiis a traditional medicinal plant popularly used in China. This study intended to evaluate the antioxidant properties and the chemical components of the flavonoid-rich extracts from the flowers ofP. ostii. The results showed that the flavonoid-rich extracts from the flowers ofP. ostiihad strong scavenging capacities on 2,2'-Azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS), hydroxyls, superoxide anions, and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals in a dose-dependent manner. Five flavonoids, dihydrokaempferol (1), apigenin-7-O-β-d-glucoside (2), apigenin-7-O-β-d-neohesperidoside (3), kaempferol-7-O-β-d-glucopyranoside (4), and kaempferol-3-O-β-d-glucopyranosyl-7-O-β-d-glucopyranoside (5), were isolated from the flavonoid-rich extracts of the flowers ofP. ostii. High-performance liquid chromatography (HPLC) analysis revealed that compounds3and4were abundant in theP. ostiiflower and in flavonoid-rich extracts. The main components of the flower ofP. ostiiare flavonoids. The high antioxidant activity of the flavonoid-rich extracts may be attributed to the high content of flavonoids. The five isolated flavonoids were the primary antioxidant ingredients, and may play important roles in the strong antioxidant activities of this flower. Based on the obtained results, the flower ofP. ostiicould be a potential source of natural antioxidants in food and pharmaceutical applications.
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China. huifangz@163.com.
authors.forename: Huifang
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China. xiaofl@163.com.
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Li
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China. kewu@126.com.
authors.forename: Ke
authors.initials: K
authors.lastname: Wu
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China. mengkw@163.com.
authors.forename: Mengke
authors.initials: M
authors.lastname: Wang
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China. liuputju@163.com.
authors.forename: Pu
authors.initials: P
authors.lastname: Liu
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China. xswang@126.com.
authors.forename: Xinsheng
authors.initials: X
authors.lastname: Wang
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China. dengliu20022002@163.com.
authors.forename: Ruixue
authors.initials: R
authors.lastname: Deng
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D052160:Benzothiazoles / Q000037:antagonists & inhibitors; D001713:Biphenyl Compounds / Q000037:antagonists & inhibitors; D002681:China; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D035264:Flowers / Q000737:chemistry*; D017665:Hydroxyl Radical / Q000037:antagonists & inhibitors; D044949:Kaempferols / Q000737:chemistry* / Q000302:isolation & purification; D029596:Paeonia / Q000737:chemistry*; D010851:Picrates / Q000037:antagonists & inhibitors; D010936:Plant Extracts / Q000737:chemistry; D010946:Plants, Medicinal; D012996:Solutions; D013451:Sulfonic Acids / Q000037:antagonists & inhibitors; D013481:Superoxides / Q000037:antagonists & inhibitors
chemical_list: D000975:Antioxidants; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D005419:Flavonoids; D044949:Kaempferols; D010851:Picrates; D010936:Plant Extracts; D012996:Solutions; D013451:Sulfonic Acids; D013481:Superoxides; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D017665:Hydroxyl Radical; C004931:1,1-diphenyl-2-picrylhydrazyl
keywords: Paeonia ostii; chemical constituents; flavonoids of peony flower; natural antioxidant