title: Integration of Curved D-Type Optical Fiber Sensor with Microfluidic Chip.
abstract: A curved D-type optical fiber sensor (OFS) combined with a microfluidic chip is proposed. This OFS, based on surface plasmon resonance (SPR) of the Kretchmann's configuration, is applied as a biosensor to measure the concentrations of different bio-liquids such as ethanol, methanol, and glucose solutions. The SPR phenomenon is attained by using the optical fiber to guide the light source to reach the side-polished, gold-coated region. Integrating this OFS with a polymethylmethacrylate (PMMA)-based microfluidic chip, the SPR spectra for liquids with different refractive indices are recorded. Experimentally, the sensitivity of the current biosensor was calculated to be in the order of 10-5RIU. This microfluidic chip-integrated OFS could be valuable for monitoring subtle changes in biological samples such as blood sugar, allergen, and biomolecular interactions.
authors.affiliation: Department of Physics, Fu-Jen Catholic University, New Taipei City 24205, Taiwan. 089957@mail.fju.edu.tw.
authors.forename: Yung-Shin
authors.initials: YS
authors.lastname: Sun
authors.affiliation: Department of Physics, Fu-Jen Catholic University, New Taipei City 24205, Taiwan. rmp410797@gmail.com.
authors.forename: Chang-Jyun
authors.initials: CJ
authors.lastname: Li
authors.affiliation: Department of Physics, Fu-Jen Catholic University, New Taipei City 24205, Taiwan. 054326@mail.fju.edu.tw.|Graduate Institute of Applied Science and Engineering, Fu-Jen Catholic University, New Taipei City 24205, Taiwan. 054326@mail.fju.edu.tw.
authors.forename: Jin-Cherng
authors.initials: JC
authors.lastname: Hsu
keywords: biosensor; microfluidic chip; optical fiber sensor; surface plasmon resonance