title: Erectile dysfunction in male dromedary camels: Clinical findings and changes in the nitric oxide metabolite, cardiac troponin I and testosterone concentrations.
abstract: This study aimed to clarify the phenomenon of erectile dysfunction (ED) in male camels and monitor the associated changes in nitric oxide metabolite (NOM), cardiac troponin I (cTnI), and testosterone concentrations. A total 18 camels with ED and 10 controls were included in this study. The breeding history was recorded and a thorough breeding soundness examination was performed. Total nitrates and nitrites were determined in sera using the Griess assay. Serum cTnI and testosterone were assessed using ELISA. A complete blood count was also carried out. The results showed that 13/18 male camels with ED had no detectable pathologic lesions in the genital tract (ED-N), while 5/18 males showed pathology in the penis, prepuce, and testicles (ED-P). The ED-P group exhibited higher concentrations of NOMs (P = 0.003), white blood cells (P = 0.0001), and neutrophils (P = 0.001) than the ED-N and control groups. The ED-P and ED-N groups had higher concentrations of cTnI than the control group (P = 0.0001). Testosterone concentration did not differ among the groups. In conclusion, the ED in the camels was associated with a rise in cTnI, probably due to myositic damage. Most of the ED cases in the camels had apparently normal genital organs. In the cases of ED in male camels with detectable pathologic lesions on their genital organs, a rise in NOMs, white blood cells, and neutrophils was observed.
authors.affiliation: Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Qassim, Saudi Arabia; Department of Theriogenology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt. Electronic address: derar40@yahoo.com.
authors.forename: Derar
authors.initials: D
authors.lastname: Derar
authors.affiliation: Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Qassim, Saudi Arabia; Department of Theriogenology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Ali
authors.affiliation: Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Qassim, Saudi Arabia; Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Tharwat
authors.affiliation: Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Qassim, Saudi Arabia.
authors.forename: Fahd
authors.initials: F
authors.lastname: Al-Sobayil
authors.affiliation: Department of Animal production, College of Agriculture and Veterinary Medicine, Qassim University, Qassim, Saudi Arabia.
authors.forename: Moustafa M
authors.initials: MM
authors.lastname: Zeitoun
mesh_terms: D000818:Animals; D001772:Blood Cell Count / Q000662:veterinary; D002162:Camelus / Q000502:physiology*; D004797:Enzyme-Linked Immunosorbent Assay; D007172:Erectile Dysfunction / Q000662:veterinary*; D005837:Genitalia, Male / Q000473:pathology / Q000503:physiopathology; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism*; D014336:Troponin / Q000378:metabolism*
chemical_list: D014336:Troponin; D009569:Nitric Oxide; D013739:Testosterone
keywords: Cardiac troponin I; Erectile dysfunction; Male dromedary camel; Nitric oxide; Testosterone