title: Recurrent pneumothorax related to diffuse dendriform pulmonary ossification in genetically predisposed individual.
abstract: Diffuse pulmonary ossification (DPO) is a rare disease with unknown pathogenesis, clinical manifestations, and treatment options. This report describes the diagnosis of DPO in an otherwise healthy 26-year-old man with recurrent spontaneous pneumothorax. His father was diagnosed with a similar lung condition in his 30's with computed tomography (CT) images that were strikingly similar to those of the patient. This report suggests that DPO can induce spontaneous pneumothorax and its pathogenesis may have a possible genetic predisposition that needs further research.
authors.affiliation: Departments of Medicine, Pathology and Laboratory Medicine and Radiology University of British Columbia Vancouver Canada.
authors.forename: Amy Po Yu
authors.initials: AP
authors.lastname: Tsai
authors.affiliation: Departments of Medicine, Pathology and Laboratory Medicine and Radiology University of British Columbia Vancouver Canada.
authors.forename: John C
authors.initials: JC
authors.lastname: English
authors.affiliation: Departments of Medicine, Pathology and Laboratory Medicine and Radiology University of British Columbia Vancouver Canada.
authors.forename: Darra
authors.initials: D
authors.lastname: Murphy
authors.affiliation: Departments of Medicine, Pathology and Laboratory Medicine and Radiology University of British Columbia Vancouver Canada.
authors.forename: Don D
authors.initials: DD
authors.lastname: Sin
keywords: Genetics; pneumothorax; pulmonary ossification; rare lung disease