title: Green Organocatalytic Synthesis of Isoxazolines via a One-Pot Oxidation of Allyloximes.
abstract: A green, sustainable, organocatalytic, and efficient synthesis of isoxazolines from allyloximes was developed. A 2,2,2-trifluoroacetophenone-catalyzed oxidation of allyloximes, utilizing H2O2as the green oxidant, was taken advantage of in order to introduce a cheap and environmentally friendly protocol for the synthesis of substituted isoxazolines. A variety of substitution patterns, both aromatic and aliphatic moieties, are well tolerated, leading to isoxazolines in moderate to excellent yields.
authors.affiliation: Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens , Panepistimiopolis, Athens 15771, Greece.
authors.forename: Ierasia
authors.initials: I
authors.lastname: Triandafillidi
authors.affiliation: Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens , Panepistimiopolis, Athens 15771, Greece.
authors.forename: Christoforos G
authors.identifier: 0000-0002-4762-7682
authors.initials: CG
authors.lastname: Kokotos