title: Glucose homeostasis abnormalities among Cameroon patients with newly diagnosed hypertension.
abstract: The authors assessed the frequency of glucose homeostasis abnormalities among 839 Cameroonians with newly diagnosed hypertension (mean age: 50.8±11 years; 49.9% female) in a cross-sectional survey conducted at the Douala General Hospital, Douala, Cameroon. In all participants, blood pressure, fasting plasma glucose (FPG), and lipids were recorded. Impaired fasting glycemia was described as an FPG level between 100 and 125 mg/dL and provisional diabetes as an FPG level ≥126 mg/dL. The FPG was 101±30 mg/dL. The overall proportion of abnormal glucose homeostasis was 38.3%, while 7.7% of patients (n=65) had known diabetes. A total of 23.7% (n=199) had impaired fasting glycemia and 6.8% (n=57) had provisional diabetes. Multivariable logistic regression revealed that male sex (odds ratio [OR], 1.53; 95% confidence interval [CI], 1.15-2.06), age older than 55 years (OR, 1.55; 95% CI, 1.15-2.09), and low-density lipoprotein cholesterol >1 g/L (OR, 1.34; 95% CI, 1.00-1.82) were independently associated with abnormal glucose homeostasis (all P<.05). Glucose homeostasis abnormalities are highly prevalent among Cameroonian patients with newly diagnosed hypertension.
authors.affiliation: Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.|Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
authors.forename: Félicité
authors.initials: F
authors.lastname: Kamdem
authors.affiliation: Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
authors.forename: Daniel
authors.initials: D
authors.lastname: Lemogoum
authors.affiliation: Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.|Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
authors.forename: Marie-Solange
authors.initials: MS
authors.lastname: Doualla
authors.affiliation: Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.|Faculty of Health Sciences, University of Buea, Buea, Cameroon.
authors.forename: Fernando
authors.initials: F
authors.lastname: Kemta Lepka
authors.affiliation: Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.
authors.forename: Elvis
authors.initials: E
authors.lastname: Temfack
authors.affiliation: Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.
authors.forename: Yvette
authors.initials: Y
authors.lastname: Ngo Nouga
authors.affiliation: Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.
authors.forename: Caroline
authors.initials: C
authors.lastname: Kenmegne
authors.affiliation: Internal Medicine Unit, Douala General Hospital, Douala, Cameroon.|Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
authors.forename: Henry
authors.initials: H
authors.lastname: Luma
authors.affiliation: Endocrinologyand Nutrition Unit, Cliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium.
authors.forename: Michel P
authors.initials: MP
authors.lastname: Hermans
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D001794:Blood Pressure / Q000502:physiology; D001795:Blood Pressure Determination / Q000379:methods; D002163:Cameroon / Q000453:epidemiology; D008078:Cholesterol, LDL; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000097:blood / Q000453:epidemiology; D005215:Fasting / Q000097:blood*; D005260:Female; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000097:blood / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors
chemical_list: D001786:Blood Glucose; D008078:Cholesterol, LDL; D008055:Lipids
keywords: Cameroon; cardiovascular risk factors; diabetes; glucose homeostasis abnormalities; hypertension; impaired fasting glycemia; provisional diabetes