title: Oncocytic Pleomorphic Adenoma of Palatal Salivary Gland with Macrophages and Giant Cells Associated with Cholesterol Crystals.
abstract: Pleomorphic adenoma (PA) is the most common salivary gland tumor characterized by histo-morphological diversity in the form of myxoid, hyalinized, chondroid, osseous, and squamous areas. In this paper, we report a rare case of predominantly oncocytic variant of PA in a 45-year-old male patient on the posterior palatal region. Microscopic examination showed homogenous eosinophilic cellular mass composed of epithelial components arranged in the form of tubular and solid patterns. The polygonal and oval cells showed abundant dark eosinophilic granular cytoplasm. The cell borders were distinct with a central nucleus showing prominent nucleoli. Interestingly at few places, cholesterol clefts were seen surrounded by macrophages and giant cells. The tumor was surgically excised with no evidence of recurrence after 2 years.
authors.affiliation: Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital , Dr. D.Y. Patil Vidyapeeth, Maharashtra, India.
authors.forename: Gargi S
authors.initials: GS
authors.lastname: Sarode
authors.affiliation: Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital , Dr. D.Y. Patil Vidyapeeth, Maharashtra, India.
authors.forename: Sachin C
authors.initials: SC
authors.lastname: Sarode
authors.affiliation: Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University , Saudi Arabia.
authors.forename: Shankargouda
authors.initials: S
authors.lastname: Patil
authors.affiliation: Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University , Saudi Arabia.
authors.forename: Sukumaran
authors.initials: S
authors.lastname: Anil
keywords: Salivary gland tumor; cholesterol crystals; oncocytes; pleomorphic adenoma