title: Carbamazepine-induced angioedema.
abstract: Angioedema is a rare adverse reaction of carbamazepine, which causes localized tissue edema in submucosal and subcutaneous tissue mediated by histamine, serotonin, and kinins (bradykinin). We report a case of 34-year-old female who developed angioedema, 24 h after administration of carbamazepine for treating bipolar disorder. Patient's symptoms responded rapidly with antihistamine therapy and with the withdrawal of carbamazepine, the offending drug. Carbamazepine-induced angioedema is a life-threatening reaction which requires immediate treatment and monitoring in order to avoid morbidity and mortality.
authors.affiliation: Department of Pharmacology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
authors.forename: Ansha
authors.initials: A
authors.lastname: Subramanian
authors.affiliation: Department of Pharmacology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
authors.forename: Mangaiarkkarasi
authors.initials: M
authors.lastname: Adhimoolam
authors.affiliation: Department of Pharmacology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
authors.forename: Senthil
authors.initials: S
authors.lastname: Gopalakrishnan
authors.affiliation: Department of Pharmacology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
authors.forename: Meher Ali
authors.initials: MA
authors.lastname: Rajamohammed
keywords: Angioedema; antiepileptic drug; carbamazepine; cutaneous reaction