title: Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp. TJ507A.
abstract: Two new functionalized ergostane-type steroids, phomopsterones A (1) and B (2), were isolated from the plant-derived Phomopsis sp. TJ507A. Their structures were determined on the basis of spectroscopic data, a modified Mosher's method, X-ray crystallographic analysis, and quantum chemical calculations. Compound 1 is an unprecedented ergosteroid featuring a rearranged bicyclo[3.3.1]nonane motif resulting from B-ring scission and a subsequent 180° rotation of the ring A during biosynthesis. Compound 2 exhibited anti-inflammatory activity.
authors.forename: Zhengxi
authors.initials: Z
authors.lastname: Hu
authors.forename: Ye
authors.initials: Y
authors.lastname: Wu
authors.forename: Shuangshuang
authors.initials: S
authors.lastname: Xie
authors.forename: Weiguang
authors.initials: W
authors.lastname: Sun
authors.forename: Yi
authors.initials: Y
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, P. R. China.
authors.forename: Xiao-Nian
authors.initials: XN
authors.lastname: Li
authors.forename: Junjun
authors.initials: J
authors.lastname: Liu
authors.forename: Hua
authors.initials: H
authors.lastname: Li
authors.forename: Jianping
authors.initials: J
authors.lastname: Wang
authors.forename: Zengwei
authors.initials: Z
authors.lastname: Luo
authors.forename: Yongbo
authors.identifier: 0000-0001-9133-6439
authors.initials: Y
authors.lastname: Xue
authors.forename: Yonghui
authors.identifier: 0000-0002-7222-2142
authors.initials: Y
authors.lastname: Zhang