title: Self-assembly of acetylated dextran with various acetylation degrees in aqueous solutions: Studied by light scattering.
abstract: Self-assembly of acetylated dextran (Ac-DEXs) was investigated with a modified dextran with acetic anhydride in the presence of pyridine. The effect of acetylation degree on solution properties has been investigated by static and dynamic light scattering (DLS). Molecular weight (Mw) and the radius of gyration (Rg) of dextran significantly increased with acetylation degree due to the aggregates formation. However, those aggregates noticeably reduced with further increase of acetylation degree. It suggested that the aggregates have shrinkage. The aggregate formation is clearly confirmed by DLS analysis in the presence of the bimodal relaxation distribution for Ac-DEXs. The hydrodynamic radius (Rh) of fast and slow mode is distinctly corresponded with single dextran macromolecules and aggregates, respectively. The Rhof aggregates varied slightly with increasing acetylation degree. The aggregates of Ac-DEXs represent hard spherical nanoparticles whereas the random coil structure is found in dextran. Formation of gel nanoparticles was monitored at the highest acetylated substitution.
authors.affiliation: Micro/Nano Technology Center, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan.
authors.forename: Isala
authors.initials: I
authors.lastname: Dueramae
authors.affiliation: Faculty of Science and Technology, Gunma University, Tenjin-cho 1-5-1, Kiryu-shi, Gunma 376-8515, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Yoneyama
authors.affiliation: Department of Physics, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Shinyashiki
authors.affiliation: Department of Physics, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Yagihara
authors.affiliation: Micro/Nano Technology Center, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan; Department of Physics, Tokai University, Kitakaname, Hiratsuka-shi, Kanagawa 259-1292, Japan. Electronic address: rkita@keyaki.cc.u-tokai.ac.jp.
authors.forename: Rio
authors.initials: R
authors.lastname: Kita
keywords: Acetylation process; Dextran; Light scattering; Self-assembly; Solution properties