title: Randomised feasibility study of a novel experience-based internet intervention to support self-management in chronic asthma.
abstract: To determine the feasibility of a randomised controlled trial (RCT) assessing the effects of an experience-based website as a resource for the self-management of chronic asthma.
  
  
  
  Feasibility, single-blind RCT in 2 regions of England. Randomisation used computer-generated random number sequence in a 1:1 ratio, after baseline data collection, to website access for 2 weeks.
  
  
  
  Adults (age ≥18 years), with clinically diagnosed asthma as coded in their primary care electronic record, prescribed inhaled corticosteroids for at least 3 months in the previous year, were recruited from 9 general practices.
  
  
  
  The EXPERT asthma intervention is an interactive PC/laptop/tablet/smartphone compatible website designed with extensive input from adults with asthma. It provides experience-based information and aims to support subjective perception of self-efficacy, self-management and improve health status.
  
  
  
  Primary outcomes were consent/recruitment, website usage and completion of outcome measures. Secondary outcomes included Partners in Health (PIH) questionnaire, the Chronic Disease Self-Efficacy Scale, the SF36 and the E-Health Impact Questionnaire. Participant blinding postrandomisation was not possible. The analysis was blind to allocation.
  
  
  
  Recruitment target exceeded. 148 participants randomised (73 intervention group). Age range 19-84 years; 59% female. 121 of 148 (84%; 62 intervention group) followed up. The median number of logins was 2 (IQR 2-3, range 1-48). Minimal differences of change from baseline between groups; both showed improvement in health state or management of their condition with no significant differences between arms. No adverse events.
  
  
  
  Recruitment and retention confirmed feasibility. The trends towards improved outcomes suggest that further research on digital interventions based on exposure to others' personal experiences may be of value in the self-management of chronic asthma.
  
  
  
  ISRCTN29549695; Results.
authors.affiliation: Nuffield Department of Primary Care Health Sciences, Health Experiences Research Group, University of Oxford, Oxford, UK.
authors.forename: Nikki
authors.identifier: 0000-0001-9002-3588
authors.initials: N
authors.lastname: Newhouse
authors.affiliation: Nuffield Department of Primary Care Health Sciences, Health Experiences Research Group, University of Oxford, Oxford, UK.
authors.forename: Angela
authors.initials: A
authors.lastname: Martin
authors.affiliation: Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
authors.forename: Sena
authors.initials: S
authors.lastname: Jawad
authors.affiliation: Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
authors.forename: Ly-Mee
authors.identifier: 0000-0003-0331-7364
authors.initials: LM
authors.lastname: Yu
authors.affiliation: Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
authors.forename: Mina
authors.initials: M
authors.lastname: Davoudianfar
authors.affiliation: Nuffield Department of Primary Care Health Sciences, Health Experiences Research Group, University of Oxford, Oxford, UK.
authors.forename: Louise
authors.initials: L
authors.lastname: Locock
authors.affiliation: Nuffield Department of Primary Care Health Sciences, Health Experiences Research Group, University of Oxford, Oxford, UK.
authors.forename: Sue
authors.initials: S
authors.lastname: Ziebland
authors.affiliation: Nuffield Department of Primary Care Health Sciences, Health Experiences Research Group, University of Oxford, Oxford, UK.
authors.forename: John
authors.initials: J
authors.lastname: Powell
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000628:therapy*; D002908:Chronic Disease / Q000628:therapy; D005240:Feasibility Studies; D005260:Female; D006293:Health Promotion / Q000379:methods*; D006304:Health Status; D006801:Humans; D020407:Internet; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D012648:Self Care; D020377:Self Efficacy; D000073278:Self-Management; D016037:Single-Blind Method; D011795:Surveys and Questionnaires; D017216:Telemedicine / Q000379:methods*; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones
keywords: RESPIRATORY MEDICINE (see Thoracic Medicine)