title: Visible-Light-Induced Acetalization of Aldehydes with Alcohols.
abstract: In this work, we have achieved a simple and general method for acetalization of aldehydes by means of a photochemical reaction under low-energy visible light irradiation. A broad range of aromatic, heteroaromatic, and aliphatic aldehydes have been protected under neutral conditions in good to excellent yields using a catalytic amount of Eosin Y as the photocatalyst. Our visible light mediated acetalization strategies are successful for more challenging acid-sensitive aldehydes and sterically hindered aldehydes. Notably, this protocol is chemoselective to aldehydes, while ketones remain intact.
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University , Wuhan, Hubei 430072, P. R. China.
authors.forename: Hong
authors.initials: H
authors.lastname: Yi
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University , Wuhan, Hubei 430072, P. R. China.
authors.forename: Linbin
authors.initials: L
authors.lastname: Niu
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University , Wuhan, Hubei 430072, P. R. China.
authors.forename: Shengchun
authors.initials: S
authors.lastname: Wang
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University , Wuhan, Hubei 430072, P. R. China.
authors.forename: Tianyi
authors.initials: T
authors.lastname: Liu
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University , Wuhan, Hubei 430072, P. R. China.
authors.forename: Atul K
authors.initials: AK
authors.lastname: Singh
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University , Wuhan, Hubei 430072, P. R. China.|National Research Center for Carbohydrate Synthesis, Jiangxi Normal University , Nanchang, Jiangxi 330022, P. R. China.
authors.forename: Aiwen
authors.identifier: 0000-0001-8417-3061
authors.initials: A
authors.lastname: Lei