title: DIFFERENCES IN ECG CHARACTERISTICS AND CO-MORBIDITIES AMONG PATIENTS WHO UNDERWENT ELECTIVE SURGICAL REPAIR.
abstract: The aim of the study was to assess differences in ECG features and prevalence of comorbidies between two groups of patiens: with Abdominal Aortic Aneurism (AAA) and Aorto-Iliac Occlusive Desieses-Lerish Syndrome (LS). Data was collected for all consecutive adult patients who underwent elective surgical repair of AAA (fusiform aneurysm) or LS at "The Center of Vascular and Heart Diseases" (Tbilisi, Georgia) between 2010 and 2014. We studied a prevalence of Arterial Hypertension (AHT); Diabetes mellitus (DM); Renal Failure (RF),Peripheral Artery Disease (PAD), Coronary Artery Disease (CAD) and rate of coronary revascularization in these patients; We also, investigate some of the electrocariographic characteristics: Corrected QT interval(QTC),QT dispersion(QTD). The majority of patients were mail (92% in both groups). Prevalence rate of CAD didn't differ significantly between groups with LS and AAA (37% and 39%P=0.7000 respectively). Rate of revascularization was (7% and 6% P=0.577 respectively). Prevalence rate of DM was higher in patients with LS compared with AAA (27%and 8%P=0.0000 respectively); PAD was more prevalent in LS group (98% and 48% P=0.0000 respectively). RF was less prevalent in patients with LS as compared with AAA (51% and 64%P=0.0200). Prevalence rate of AHT was significantly low in LS than in AAA (49% and 65%P=0.0000 respectively). A prevalence rate of increased QTd (>0.07ms) was high in LS group but the difference between these two groups was not statistically significant (16% and 9% P=0.1563 respectively). Absolute number of prolonged QTd was high in LS group in comparison with AAA and this difference was statistically significant (0.04±0.026 and 0.02±0.028 P=0.0092 respectively).QTC remained in normal range in both groups. Rates of CAD and coronary revascularization did not differ between patients with AAA and LS. The high incidence of DM and PAD was found in patients with LS as well as high HR and prolonged QTd. Prevalence Rate of AHT, RF was higher in patients with AAA as compared with LS group. These findings indicates: a)Different composition of risk factors in two groups. However, both groups of patients are at increased risk of development of coronary events and this circumstance may be considered as a predictor of worse prognosis. b) High incidence of renal failure in AAA group may contribute a progression of renal dysfunction in this patients during /after surgery.c) A prolonged QTd was high in LS group which may contribute heightened risk of fatal arrhythmias in this patients. Further studies are needed for evaluation a prevalence rate of prolonged QTd in the large population.
authors.affiliation: Iv. Javakhishvili Tbilisi State University; The Center of Vascular and Heart Diseases, Tbilisi, Georgia.
authors.forename: I
authors.initials: I
authors.lastname: Botchorishvili
authors.affiliation: Iv. Javakhishvili Tbilisi State University; The Center of Vascular and Heart Diseases, Tbilisi, Georgia.
authors.forename: N
authors.initials: N
authors.lastname: Sharashidze
authors.affiliation: Iv. Javakhishvili Tbilisi State University; The Center of Vascular and Heart Diseases, Tbilisi, Georgia.
authors.forename: N
authors.initials: N
authors.lastname: Pargalava
authors.affiliation: Iv. Javakhishvili Tbilisi State University; The Center of Vascular and Heart Diseases, Tbilisi, Georgia.
authors.forename: Z
authors.initials: Z
authors.lastname: Pagava
authors.affiliation: Iv. Javakhishvili Tbilisi State University; The Center of Vascular and Heart Diseases, Tbilisi, Georgia.
authors.forename: G
authors.initials: G
authors.lastname: Saatashvili
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery; D015897:Comorbidity; D048909:Diabetes Complications / Q000453:epidemiology / Q000503:physiopathology; D017558:Elective Surgical Procedures; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000503:physiopathology; D007925:Leriche Syndrome / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000453:epidemiology / Q000503:physiopathology; D058729:Peripheral Arterial Disease / Q000453:epidemiology / Q000503:physiopathology; D051437:Renal Insufficiency / Q000453:epidemiology / Q000503:physiopathology