title: Treatment of Vaginal Atrophy with Vaginal Estrogen Cream in Menopausal Indian Women.
abstract: OBJECTIVE
  To measure the effect of vaginal estrogen cream in the treatment of vaginal atrophy in menopausal Indian women.
  
  
  METHODS
  A total of 50 menopausal women aged between 40 and 80 years old with symptoms of vaginal atrophy were selected and treated with 0.5 g vaginal estrogen cream, twice weekly for 12 weeks. The women were followed-up monthly where symptom score, Genital Health Clinical Evaluation (GHCE) score, vaginal pH, and vaginal maturation index (VMI) were assessed and compared to baseline data. Any adverse events were recorded.
  
  
  RESULTS
  There was a significant improvement (p< 0.010) in complaints such as vaginal dryness, itching, burning, and dyspareunia at the end of the study period. The clinical improvement of these patients was reflected in a decrease in GHCE score on every visit. Vaginal pH and VMI score also showed statistically significant improvements (p <0.010). No side effects with the drugs used were recorded during the study period.
  
  
  CONCLUSIONS
  Vaginal estrogen cream causes symptomatic relief in women of menopausal age in India suffering from vaginal atrophy.
authors.affiliation: Department of Obstetrics & Gynecology, Government Medical College, Baroda, Gujarat, India.
authors.forename: Maitri
authors.initials: M
authors.lastname: Shah
authors.affiliation: Department of Obstetrics & Gynecology, Government Medical College, Baroda, Gujarat, India.
authors.forename: Zalak
authors.initials: Z
authors.lastname: Karena
authors.affiliation: Department of Community Medicine, Government Medical College, Baroda, Gujarat, India.
authors.forename: Sangita V
authors.initials: SV
authors.lastname: Patel
authors.affiliation: Department of Community Medicine, Government Medical College, Baroda, Gujarat, India.
authors.forename: Niyati
authors.initials: N
authors.lastname: Parmar
authors.affiliation: Pfizer India Ltd. Patel Estate, Jogeshwari (East), Mumbai, India.
authors.forename: Pawan K
authors.initials: PK
authors.lastname: Singh
authors.affiliation: Pfizer India Ltd. Patel Estate, Jogeshwari (East), Mumbai, India.
authors.forename: Atul
authors.initials: A
authors.lastname: Sharma
keywords: Atrophy; Estrogens, Conjugated; Postmenopause; Vaginal Cream; Women