title: Differential Item Functioning (DIF) and Subsequent Bias in Group Comparisons using a Composite Measurement Scale: A Simulation Study.
abstract: OBJECTIVE
  To determine the conditions in which the estimation of a difference between groups for a construct evaluated using a composite measurement scale is biased if the presence of Differential Item Functioning (DIF) is not taken into account.
  
  
  METHODS
  Datasets were generated using the Partial Credit Model to simulate 642 realistic scenarios. The effect of seven factors on the bias on the estimated difference between groups was evaluated using ANOVA: sample size, true difference between groups, number of items in the scale, proportion of items showing DIF, DIF-size for these items, position of these items location parameters along the latent trait, and uniform/non-uniform DIF.
  
  
  RESULTS
  For uniform DIF, only the DIF-size and the proportion of items showing DIF (and their interaction term) had meaningful effects. The effect of non-uniform DIF was negligible.
  
  
  CONCLUSIONS
  The measurement bias resulting from DIF was quantified in various realistic conditions of composite measurement scale use.
authors.affiliation: Alexandra Rouquette, Hotel-Dieu Hospital, Biostatistics and Epidemiology Department, 1 place du parvis Notre-Dame, 75181 Paris cedex 04, France, alex.rouquette@gmail.com.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Rouquette
authors.forename: Jean-Benoit
authors.initials: JB
authors.lastname: Hardouin
authors.forename: Joel
authors.initials: J
authors.lastname: Coste
mesh_terms: D000465:Algorithms; D015982:Bias; D003627:Data Interpretation, Statistical; D059026:Diagnostic Self Evaluation; D006801:Humans; D015233:Models, Statistical; D011594:Psychometrics / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires