title: Progress towards Rapid Detection of Measles Vaccine Strains: a Tool To Inform Public Health Interventions.
abstract: Rapid differentiation of vaccine from wild-type strains in suspect measles cases is a valuable epidemiological tool that informs the public health response to this highly infectious disease. Few public health laboratories sequence measles virus-positive specimens to determine genotype, and the vaccine-specific real-time reverse transcriptase PCR (rRT-PCR) assay described by F. Roy et al. (J. Clin. Microbiol. 55:735-743, 2017, https://doi.org/10.1128/JCM.01879-16) offers a rapid, easily adoptable method to identify measles vaccine strains in suspect cases.
authors.affiliation: Viral and Rickettsial Disease Laboratory, California Department of Public Health, Richmond, California, USA jill.hacker@cdph.ca.gov.
authors.forename: Jill K
authors.initials: JK
authors.lastname: Hacker
mesh_terms: D006801:Humans; D008457:Measles; D008458:Measles Vaccine / Q000235:genetics*; D008459:Measles virus / Q000235:genetics*; D011634:Public Health; D012367:RNA, Viral / Q000032:analysis; D060888:Real-Time Polymerase Chain Reaction; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D008458:Measles Vaccine; D012367:RNA, Viral