title: Knee Kinematic and Clinical Outcomes Evolution Before, 3 Months, and 1 Year After Total Knee Arthroplasty.
abstract: The aim of this study was to describe the evolution of kinematic and clinical outcomes of a large patient cohort with knee osteoarthritis from before surgery (V1) to 3 months (V2) and 1 year (V3) after a total knee arthroplasty (TKA).
  
  
  
  The patients were evaluated at each visit (118 patients at V1, 93 patients at V2, and 79 patients at V3) during a clinical gait analysis and were compared with a matched control group of healthy adults (CG). The kinematic parameters, the Western Ontario and MacMaster Osteoarthritis Index (WOMAC), quality of life, and patient satisfaction were assessed. Gait velocity and knee range of motion (ROM) as well as clinical parameters were compared at each visit with CG was based on the unpaired samples t-test. To determine changes in the data at baseline, 3 months, and 1 year after surgery in the patient groups, repeated-measure analysis of variance was conducted (P < .05). Pearson correlation was used to examine relationships between clinical and biomechanical outcomes.
  
  
  
  One year after TKA (V3) compared to V1 and V2, the ROM of the operated knee during gait was significantly improved (V1: 44.2 ± 8.8° vs V3: 47.5 ± 7.1°, P < .001, and V2: 42.2 ± 9.3° vs V3: 47.5 ± 7.1°, P = .001), as was the gait velocity (V1: 1.0 ± 0.2 and V2: 1.1 ± 0.2 m/s vs V3: 1.3 ± 0.2 m/s, P < .001). The WOMAC and knee pain were significantly better 1 year after TKA. No strong relationships have been found between clinical parameters and knee kinematics.
  
  
  
  This study showed that 1 year after TKA, patients exhibited improved gait velocity and ROM and experienced a significant decrease in the level of pain and an increased clinical score (although different from CG).
authors.affiliation: Willy Taillard Laboratory of Kinesiology, Geneva University Hospitals, Geneva University, Geneva, Switzerland; Division of Orthopaedics and Trauma Surgery, Geneva University Hospitals, Faculty of Medecine, Geneva, Switzerland.
authors.forename: Alice
authors.initials: A
authors.lastname: Bonnefoy-Mazure
authors.affiliation: Willy Taillard Laboratory of Kinesiology, Geneva University Hospitals, Geneva University, Geneva, Switzerland; Division of Orthopaedics and Trauma Surgery, Geneva University Hospitals, Faculty of Medecine, Geneva, Switzerland.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Armand
authors.affiliation: Laboratoire d'Exploration Fonctionnelle Clinique du Mouvement, CHRU de Besançon, Besançon, France; Centre d'Investigation Clinique INSERM CIT 808, CHRU de Besançon, Besançon, France.
authors.forename: Yoshisama
authors.initials: Y
authors.lastname: Sagawa
authors.affiliation: Division of Orthopaedics and Trauma Surgery, Geneva University Hospitals, Faculty of Medecine, Geneva, Switzerland.
authors.forename: Domizio
authors.initials: D
authors.lastname: Suvà
authors.affiliation: Division of Orthopaedics and Trauma Surgery, Geneva University Hospitals, Faculty of Medecine, Geneva, Switzerland.
authors.forename: Hermes
authors.initials: H
authors.lastname: Miozzari
authors.affiliation: Department of Kinesiology, Medicine Faculty, Laval University, Quebec, Quebec, Canada; Center for Interdisciplinary Research in Rehabilitation and Social Integration, Quebec, Quebec, Canada.
authors.forename: Katia
authors.initials: K
authors.lastname: Turcot
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D005260:Female; D005684:Gait; D006801:Humans; D007717:Knee / Q000601:surgery; D007719:Knee Joint / Q000502:physiology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000503:physiopathology* / Q000601:surgery; D017060:Patient Satisfaction; D011446:Prospective Studies; D011788:Quality of Life; D016059:Range of Motion, Articular; D020127:Recovery of Function
keywords: gait; knee kinematic; longitudinal study; osteoarthritis; total knee arthroplasty