title: Comparison of Enterohemorrhagic Escherichia coli (EHEC) O157 and EHEC Non-O157 Isolates from Patients with Diarrhea in Korea.
abstract: We compared 47 enterohemorrhagic Escherichia coli (EHEC) O157 isolates with 184 EHEC non-O157 isolates from Korean patients with diarrhea. In the O157 group, the strains harboring both Shiga toxin genes (stx1 and stx2) were detected with highest frequency, whereas the strains harboring only stx1 gene were most frequently detected in the non-O157 group. Eight virulence genes (eaeA, hlyA, ehx, iha, efa1, tir, toxB, and espA) were found to show a higher frequency of occurrence in the O157 group than in the non-O157 group. In addition, the symptom of bloody diarrhea was exhibited at a higher rate in the O157 group (51.1%) than in the non-O157 group (16.8%). Our findings demonstrate that EHEC O157 strains are more frequently implicated in cases of bloody diarrhea in the Korean population than EHEC non-O157 strains.
authors.affiliation: Division of Enteric Diseases, Center for Infectious Diseases, Korea National Institute of Health.
authors.forename: Kyung-Hwan
authors.initials: KH
authors.lastname: Oh
authors.affiliation: Division of Enteric Diseases, Center for Infectious Diseases, Korea National Institute of Health.
authors.forename: Su-Mi
authors.initials: SM
authors.lastname: Jung
authors.affiliation: Division of Enteric Diseases, Center for Infectious Diseases, Korea National Institute of Health.
authors.forename: Eunkyung
authors.initials: E
authors.lastname: Shin
authors.affiliation: Division of Enteric Diseases, Center for Infectious Diseases, Korea National Institute of Health.
authors.forename: Gyung Tae
authors.initials: GT
authors.lastname: Chung
authors.affiliation: Center for Infectious Diseases, Korea National Institute of Health.
authors.forename: Won-Keun
authors.initials: WK
authors.lastname: Seong
authors.affiliation: Division of Enteric Diseases, Center for Infectious Diseases, Korea National Institute of Health.
authors.forename: Seung-Hak
authors.initials: SH
authors.lastname: Cho
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D054324:Enterohemorrhagic Escherichia coli / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D019081:O Antigens / Q000032:analysis*; D065288:Serogroup; D022622:Shiga Toxin 1 / Q000235:genetics*; D022641:Shiga Toxin 2 / Q000235:genetics*; D037521:Virulence Factors / Q000235:genetics; D055815:Young Adult
chemical_list: D019081:O Antigens; D022622:Shiga Toxin 1; D022641:Shiga Toxin 2; D037521:Virulence Factors
keywords: O157; bloody diarrhea; enterohemorrhagic E. coli; non-O157