title: Immediate and residual effects of low-dose nandrolone decanoate and treadmill training on adipose and reproductive tissues of male Wistar rats.
abstract: BACKGROUND
  Residual effects after nandrolone decanoate (ND) treatment are not reported.
  
  
  OBJECTIVE
  Immediate and residual effects of low-dose ND and treadmill training were investigated.
  
  
  METHODS
  Male rats were trained and/or ND-treated for four weeks and the assessments were made after this period or four weeks later.
  
  
  RESULTS
  The groups did not differ in final plasma glucose or AUC of the ivGTT, but hyperinsulinemia was noticed in some trained/treated groups. Training with ND increased muscle mass and ND decreased the reproductive structures. Decreased fat with training was reversed by detraining.
  
  
  CONCLUSIONS
  The anabolic action of ND on skeletal muscle was enhanced by training. Fat and lipid changes were more linked to training/detraining, but the effects of ND on the reproductive structures persisted after treatment.
  
  
  CONCLUSIONS
  The effects of training on fat and muscle were not maintained after detraining, but low-dose ND had persistent effects on the reproductive structures.
authors.affiliation: a Academic Specialization in Physiology, State University of Maringá , Maringá, Brazil.
authors.forename: Josilene M
authors.initials: JM
authors.lastname: Rodrigues
authors.affiliation: a Academic Specialization in Physiology, State University of Maringá , Maringá, Brazil.
authors.forename: Vinicius P P
authors.initials: VP
authors.lastname: Oliveira
authors.affiliation: b Undergraduation in Physical Education, State University of Maringá , Maringá, Brazil.
authors.forename: Julia
authors.initials: J
authors.lastname: P Furlan
authors.affiliation: c Undergraduation in Biological Sciences, State University of Maringá , Maringá, Brazil.
authors.forename: Ana Claudia
authors.initials: AC
authors.lastname: Munhoz
authors.affiliation: d Undergraduation in Medicine, State University of Maringá , Maringá, Brazil , and.
authors.forename: Marcelo R
authors.initials: MR
authors.lastname: S Rempel
authors.affiliation: e Department of Physiological Sciences , State University of Maringá , Maringá, Brazil.
authors.forename: Marcia N
authors.initials: MN
authors.lastname: Brito
authors.affiliation: e Department of Physiological Sciences , State University of Maringá , Maringá, Brazil.
authors.forename: Nilton A
authors.initials: NA
authors.lastname: Brito
authors.affiliation: e Department of Physiological Sciences , State University of Maringá , Maringá, Brazil.
authors.forename: Maria M D
authors.initials: MM
authors.lastname: Pedrosa
authors.affiliation: e Department of Physiological Sciences , State University of Maringá , Maringá, Brazil.
authors.forename: Cecília E
authors.initials: CE
authors.lastname: M Costa
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects / Q000502:physiology*; D009277:Nandrolone / Q000031:analogs & derivatives* / Q000494:pharmacology; D000077603:Nandrolone Decanoate; D010805:Physical Conditioning, Animal / Q000379:methods*; D051381:Rats; D017208:Rats, Wistar; D013737:Testis / Q000187:drug effects / Q000502:physiology*
chemical_list: D009277:Nandrolone; D000077603:Nandrolone Decanoate
keywords: Nandrolone decanoate; detraining; lipid; rat; training