title: RETRACTED: Recent advances in cardiac regeneration: Stem cell, biomaterial and growth factors.
abstract: Myocardial infarction has been reported to be responsible for about 7.3 million deaths each year globally. Present treatments for myocardial infarction have been more palliative rather than curative. Over the past few years, stem cells have demonstrated its potency in regenerating damaged cardiac tissue, especially after myocardial infarction. However, limited short half-life of the protein and cell therapy and low transplanted cell survival rate as demonstrated via several clinical trials have lead to development of more potent and novel delivery systems like biomaterial delivery system and the use of various growth factors. In this review, we will be enumerating and discussing the recent advances in cardiac regeneration with focus on stem cell, biomaterial and growth factors.
authors.affiliation: Department of Cardiology, Lorestan University of Medical Sciences, Khoramabad, Iran.
authors.forename: Mostafa
authors.initials: M
authors.lastname: Cheraghi
authors.affiliation: Department of Cardiology, Lorestan University of Medical Sciences, Khoramabad, Iran.
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Namdari
authors.affiliation: Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Babak
authors.initials: B
authors.lastname: Negahdari
authors.affiliation: Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran; Razi Herbal Medicine Research Center, Lorestan University of Medical Science, Khorramabad, Iran; Department of Medical Biotechnology, School of Medicine, Lorestan University of Medical Sciences, Lorestan, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Eatemadi
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000008:administration & dosage*; D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology; D006331:Heart Diseases / Q000473:pathology / Q000628:therapy*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage*; D009206:Myocardium / Q000166:cytology / Q000473:pathology; D032383:Myocytes, Cardiac / Q000187:drug effects / Q000473:pathology / Q000502:physiology*; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*; D033581:Stem Cell Transplantation / Q000639:trends*; D013234:Stem Cells / Q000166:cytology / Q000502:physiology
chemical_list: D001672:Biocompatible Materials; D036341:Intercellular Signaling Peptides and Proteins
keywords: Biomaterials; Cell therapy; Delivery systems; Myocardial infarction; Protein therapy