title: Overview on the Role of Advance Genomics in Conservation Biology of Endangered Species.
abstract: In the recent era, due to tremendous advancement in industrialization, pollution and other anthropogenic activities have created a serious scenario for biota survival. It has been reported that present biota is entering a "sixth" mass extinction, because of chronic exposure to anthropogenic activities. Variousex situandin situmeasures have been adopted for conservation of threatened and endangered plants and animal species; however, these have been limited due to various discrepancies associated with them. Current advancement in molecular technologies, especially, genomics, is playing a very crucial role in biodiversity conservation. Advance genomics helps in identifying the segments of genome responsible for adaptation. It can also improve our understanding about microevolution through a better understanding of selection, mutation, assertive matting, and recombination. Advance genomics helps in identifying genes that are essential for fitness and ultimately for developing modern and fast monitoring tools for endangered biodiversity. This review article focuses on the applications of advanced genomics mainly demographic, adaptive genetic variations, inbreeding, hybridization and introgression, and disease susceptibilities, in the conservation of threatened biota. In short, it provides the fundamentals for novice readers and advancement in genomics for the experts working for the conservation of endangered plant and animal species.
authors.affiliation: The Key Laboratory of Aquatic Biodiversity and Conservation, Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, China.
authors.forename: Suliman
authors.initials: S
authors.lastname: Khan
authors.affiliation: The Key Laboratory of Aquatic Biodiversity and Conservation, Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, China.
authors.forename: Ghulam
authors.initials: G
authors.lastname: Nabi
authors.affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China.
authors.forename: Muhammad Wajid
authors.initials: MW
authors.lastname: Ullah
authors.affiliation: Center for Human Genome Research, Cardio-X Institute, Huazhong University of Science and Technology, Wuhan 430074, China.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Yousaf
authors.affiliation: National Key Laboratory of Crop Genetic Improvement, College of Plant Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China.
authors.forename: Sehrish
authors.initials: S
authors.lastname: Manan
authors.affiliation: Institute of Biotechnology and Genetic Engineering, The University of Agriculture, Peshawar 25000, Pakistan.
authors.forename: Rabeea
authors.initials: R
authors.lastname: Siddique
authors.affiliation: The Key Laboratory of Aquatic Biodiversity and Conservation, Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, China.
authors.forename: Hongwei
authors.identifier: 0000-0003-4823-0270
authors.initials: H
authors.lastname: Hou