title: Transcatheter Closure of Perimembranous Ventricular Septal Defects Using Dual Wire-Maintaining Technique.
abstract: OBJECTIVE
  The present study was designed to evaluate the safety and feasibility of transcatheter closure of perimembranous ventricular septal defects (PmVSDs) with dual wire-maintaining technique (DWMT).
  
  
  METHODS
  From January 2010 to December 2013, a total of 241 patients (men: 109, women: 132; mean age: 22.2±15.4 years) with congenital PmVSDs were randomised to either the conventional technique (CT) group (n=118) or the DWMT group (n=123).
  
  
  RESULTS
  In the CT group, the track wire was withdrawn before occluder insertion. In the DWMT group, the track wire was maintained in the delivery sheath during the procedure. Both the procedure time and fluoroscope time were reduced significantly in the DWMT group patients who required device replacement compared with CT group patients (median time: 46.0±14.8min vs. 56.0±15.2min, p<0.05; 15.0±11.6min vs. 22.0±10.1min, p<0.05). There was no difference in the incidence of complications between the two groups.
  
  
  CONCLUSIONS
  The DWMT is safe and feasible for transcatheter treatment of PmVSDs, especially in patients requiring device replacement, for it avoids reconstruction of the "arteriovenous wire loop", left ventriculography from the contralateral femoral route, or the use of a larger femoral artery short sheath.
authors.affiliation: Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, PR China; Department of Cardiology, East Hospital, Tongji University School of Medicine, Shanghai 200120, PR China.
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Xu
authors.affiliation: Department of Cardiology, East Hospital, Tongji University School of Medicine, Shanghai 200120, PR China.
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Gao
authors.affiliation: Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, PR China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Bai
authors.affiliation: Department of Cardiology, Fuzhou General Hospital, Fuzhou 350025, PR China.
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, PR China.
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: You
authors.affiliation: Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, PR China. Electronic address: xianxianz2010@163.com.
authors.forename: Xian-Xian
authors.initials: XX
authors.lastname: Zhao
authors.affiliation: Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, PR China. Electronic address: qywsmmu@163.com.
authors.forename: Yong-Wen
authors.initials: YW
authors.lastname: Qin
mesh_terms: D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization / Q000379:methods*; D002648:Child; D006345:Heart Septal Defects, Ventricular / Q000000981:diagnostic imaging / Q000601:surgery*; D006346:Heart Septum / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans
keywords: Dual wire-maintaining technique; Transcatheter; Ventricular septal defect