title: Amphiphilic carbon dots for sensitive detection, intracellular imaging of Al3.
abstract: In this paper, a simple and effective method was designed to synthesize hydrophobic carbon dots. Subsequently, amphiphilic fluorescent carbon dots (A-CDs) were synthesized by further surface modification. The result A-CDs show excellent optical properties with a quantum yield of 16.9%. It was interestingly found that morin (MR) and its fluorescent metal-ion complex (MR-Al3+) can successfully coordinate on the surface of A-CDs, the emission of A-CDs completely overlapped the absorption peak of MR-Al3+. Thus, the prepared A-CDs can be used as an effective fluorescent probe for Al3+based on a fluorescence resonance energy transfer process. The sensing platform can realize real-time detection of Al3+within 0.5 min. The fluorescence signals of the system were linearly correlated with the concentration of Al3+over a range of 8-20 μM, with a detection limit of 0.113 μM. The method was also successfully applied to image the distribution of Al3+in Human Umbilical Vein Endothelial Cells.
authors.affiliation: State Key Laboratory of Separation Membranes and Membrane Processes, School of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, PR China.
authors.forename: Depeng
authors.initials: D
authors.lastname: Kong
authors.affiliation: State Key Laboratory of Separation Membranes and Membrane Processes, School of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, PR China. Electronic address: yanfanyong@tjpu.edu.cn.
authors.forename: Fanyong
authors.initials: F
authors.lastname: Yan
authors.affiliation: Department of Pharmacology/Key Laboratory for Basic Pharmacology of Ministry of Education, Zunyi Medical College, Guizhou 563000, PR China.
authors.forename: Yunmei
authors.initials: Y
authors.lastname: Luo
authors.affiliation: State Key Laboratory of Separation Membranes and Membrane Processes, School of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, PR China.
authors.forename: Qianghua
authors.initials: Q
authors.lastname: Ye
authors.affiliation: State Key Laboratory of Separation Membranes and Membrane Processes, School of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, PR China.
authors.forename: Siyushan
authors.initials: S
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Separation Membranes and Membrane Processes, School of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, PR China. Electronic address: Chenlis@tjpu.edu.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Chen
mesh_terms: D000535:Aluminum / Q000032:analysis*; D002244:Carbon; D005456:Fluorescent Dyes; D061307:Human Umbilical Vein Endothelial Cells; D006801:Humans; D057230:Limit of Detection; D045663:Quantum Dots; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D002244:Carbon; D000535:Aluminum
keywords: Al(3+) detection; Amphiphilic carbon dots; Fluorescence resonance energy transfer