title: Is there a relationship between non-obstructive coronary artery disease or cardiac syndrome X and migraine? An integrated multi-disciplinary approach.
abstract: Non-obstructive coronary artery disease (CAD) which is mostly called cardiac syndrome X (CSX) is noted in about 30% of men and 40%-60% of women and seems to be incremental. In addition, frequent myocardial perfusion defects with various levels of severity are often seen in this disease. Recently, we noticed that the frequency of migraine in patients with CSX was noticeably higher than in healthy people and in CAD patients. This may support the evolving story that CSX is related to migraine and to chest pain and that CSX and migraine may have a similar pathophysiology. Hence, myocardial perfusion imaging could be used as a complement any diagnostic test to support the relation between CSX and migraine.
authors.affiliation: Department of Neurology, Bushehr University Medical Hospital, Bushehr University of Medical Sciences, Bushehr, Iran. assadipoya@yahoo.com.
authors.forename: Reza
authors.initials: R
authors.lastname: Nemati
authors.forename: Iraj
authors.initials: I
authors.lastname: Nabipour
authors.forename: Mehdi
authors.initials: M
authors.lastname: Akbarzadeh
authors.forename: Majid
authors.initials: M
authors.lastname: Assadi
mesh_terms: D015984:Causality; D015897:Comorbidity; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D019033:Delivery of Health Care, Integrated / Q000458:organization & administration; D019317:Evidence-Based Medicine; D006801:Humans; D017566:Microvascular Angina / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D008881:Migraine Disorders / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D055414:Myocardial Perfusion Imaging / Q000379:methods / Q000706:statistics & numerical data; D010348:Patient Care Team / Q000458:organization & administration; D015995:Prevalence; D012307:Risk Factors