title: Alterations of antioxidant status markers in dairy cows during lactation and in the dry period.
abstract: The purpose of the study reported in this Research Communication was to evaluate alterations in concentration of total antioxidant capacity (TAC) of plasma, plasma total thiols as markers of oxidative protein damage and malondialdehyde (as a final product of lipid peroxidation) in samples obtained at different stages of the lactation cycle and dry period of dairy cows. We found that TAC was significantly lower in the primiparous cows compared to multiparous cows. This study clearly demonstrates a need for monitoring primiparous cows during the production cycle, especially when they are faced with severe metabolic conditions. Furthermore, TAC may be a sensitive, reliable and useful indicator for measurement of cumulative effects of antioxidants as an addition to metabolic profile tests, which are currently used to analyse dairy cattle health.
authors.affiliation: Department of Animal Health Management,School of Veterinary Medicine, Shiraz University,Shiraz,Iran.
authors.forename: Arash
authors.initials: A
authors.lastname: Omidi
authors.affiliation: Department of Animal Sciences, Agriculture Faculty,University of Birjand,Birjand,Iran.
authors.forename: Mohammad Hasan
authors.initials: MH
authors.lastname: Fathi
authors.affiliation: School of Health Sciences and Social Work,University of Portsmouth,Portsmouth,UK.
authors.forename: Matthew O
authors.initials: MO
authors.lastname: Parker
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000032:analysis*; D015415:Biomarkers / Q000097:blood; D002417:Cattle / Q000502:physiology*; D005260:Female; D007774:Lactation / Q000502:physiology*; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood; D010084:Oxidation-Reduction; D010298:Parity; D049590:Postpartum Period; D013438:Sulfhydryl Compounds / Q000097:blood
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D013438:Sulfhydryl Compounds; D008315:Malondialdehyde
keywords: Antioxidant status; dairy cows; dry period; lactation cycle