title: Toxoplasmosis in Iran: A guide for general physicians working in the Iranian health network setting: A systematic review.
abstract: BACKGROUND
  Human toxoplasmosis is an important zoonotic infection worldwide which is caused by the intracellular parasiteToxoplasma gondii(T.gondii). The aim of this study was to review briefly the general aspects of toxoplasma infection in in Iranian health system network.
  
  
  METHODS
  We searched published toxoplasmosis related articles in English databases including Science Direct, Pub Med, Scopus, Google Scholar, Magiran, Iran Medex, Iran Doc and Scientific Information Database (SID) for toxoplasmosis.
  
  
  RESULTS
  Out of 1267 articles from the English and Persian databases search, 40 articles were suitable with our research objectives and so were selected for the study. It is estimated that at least a third of the world human population is infected with T.gondii, suggesting it as one of the most common parasitic infections through the world. Maternal infection during pregnancy may affect dangerous outcome for the fetus, or even cause intrauterine death. Reactivation of a previous infection in immunocompromised patient such as drug induced, AIDS and organ transplantation can cause life-threating central nervous system infection. Ocular toxoplasmosis is one of the most important causes of blindness, especially in individuals with a deficient immune system.
  
  
  CONCLUSIONS
  According to the increasing burden of toxoplasmosis on human health, the findings of this study highlight the appropriate preventive measures, diagnosis, and management of this disease.
authors.affiliation: Health Research Institute, Infectious and Tropical Disease Research Center, Joundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Seyed Mohammad
authors.initials: SM
authors.lastname: Alavi
authors.affiliation: Food and Drug Deputy, Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Leila
authors.initials: L
authors.lastname: Alavi
keywords: Epidemiology; Health center; Iran; T. gondii; Toxoplasma infection