title: Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study.
abstract: BACKGROUND
  Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly.
  
  
  METHODS
  In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and taking regular doses of aspirin. The prevalence of microscopic hematuria was compared between the elderly who took aspirin regularly and those who did not take it.
  
  
  RESULTS
  A total of 1243 individuals (54.22% males, 45.78% females) were entered in to the study. Two hundred and eighty-four (23%) elderly took regular doses of aspirin. Microscopic hematuria was seen in 305 (24.54%) elderly. The prevalence of microscopic hematuria was 27.27% in regular users of aspirin and 23.72% in non-users of aspirin (P=0.126). The prevalence of microscopic hematuria was significantly higher among the regular users of aspirin compared to non-users in multiple logistic regression analysis (P=0.035, OR=1.40, 95%CI: 1.02-1.92).
  
  
  CONCLUSIONS
  Taking regular doses of aspirin was accompanied with higher rate of microscopic hematuria in the elderly.
authors.affiliation: Department of Urology, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Emadouddin
authors.initials: E
authors.lastname: Moudi
authors.affiliation: Department of Community Medicine, Social Determinants of Health (SDH) Research Center, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Seyed-Reza
authors.initials: SR
authors.lastname: Hosseini
authors.affiliation: Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Bijani
keywords: Aspirin; Elderly; Hematuria; Prevalence