title: Association Between Cardiovascular Disease Risk Factors and Rotator Cuff Tendinopathy: A Cross-Sectional Study.
abstract: Recent evidence has found potential associations between cardiovascular disease (CVD) risk factors and common musculoskeletal disorders. We evaluated possible associations between risk factors and both glenohumeral joint pain and rotator cuff tendinopathy.
  
  
  
  Data from WISTAH hand study participants (n = 1226) were assessed for associations between Framingham Heart Study CVD risk factors and both health outcomes.
  
  
  
  A strong association was observed between CVD risk scores and both glenohumeral joint pain and rotator cuff tendinopathy. Peak odds ratios (ORs) of the adjusted models were 4.55 [95% confidence interval (95% CI) 1.97 to 10.31] and 5.97 (95% CI 2.12 to 16.83), respectively. The results show a dose-response trend of increasing risk.
  
  
  
  Individual risk factors were associated with both outcomes. Combined, CVD risk factors demonstrated a strong correlation with glenohumeral joint pain and an even stronger correlation with rotator cuff tendinopathy. Results suggest a potentially modifiable disease mechanism.
authors.affiliation: Rocky Mountain Center for Occupational and Environmental Health (RMCOEH) (Ms Applegate, Drs Thiese, Wood, Hegmann), Department of Mechanical Engineering, University of Utah, Salt Lake City, Utah (Dr Merryweather), Center for Ergonomics, University of Wisconsin-Milwaukee (Drs Kapellusch, Foster, Garg), Veterans Administration Medical Center, Milwaukee, Wisconsin (Dr Drury), and Division of Physical Medicine and Rehabilitation, University of Utah, Salt Lake City, Utah (Mr Kendall).
authors.forename: Kara Arnold
authors.initials: KA
authors.lastname: Applegate
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Thiese
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Merryweather
authors.forename: Jay
authors.initials: J
authors.lastname: Kapellusch
authors.forename: David L
authors.initials: DL
authors.lastname: Drury
authors.forename: Eric
authors.initials: E
authors.lastname: Wood
authors.forename: Richard
authors.initials: R
authors.lastname: Kendall
authors.forename: James
authors.initials: J
authors.lastname: Foster
authors.forename: Arun
authors.initials: A
authors.lastname: Garg
authors.forename: Kurt T
authors.initials: KT
authors.lastname: Hegmann
mesh_terms: D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000453:epidemiology*; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology; D006973:Hypertension / Q000453:epidemiology; D007087:Illinois / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016272:Occupational Health; D015995:Prevalence; D012307:Risk Factors; D000070636:Rotator Cuff Injuries / Q000453:epidemiology*; D012785:Shoulder Joint; D012907:Smoking / Q000453:epidemiology; D014589:Utah / Q000453:epidemiology; D014922:Wisconsin / Q000453:epidemiology