title: PulseRider for Treatment of Wide-Neck Bifurcation Intracranial Aneurysms: 6-Month Results.
abstract: OBJECTIVE
  PulseRider is a new endovascular stent dedicated to treat bifurcation intracranial aneurysms with a wide neck. Our purpose was to evaluate 6-month clinical and anatomic results of the device when used to facilitate endovascular coiling of wide-neck bifurcation aneurysms.
  
  
  METHODS
  Unruptured intracranial aneurysms coiled with PulseRider, in 6 European centers and 1 U.S. center, were retrospectively reviewed from June 2014 to October 2015. Immediate and 6-month results were evaluated independently by using the Raymond classification scale. Recanalization was defined as worsening, and progressive thrombosis was defined as improvement on the Raymond scale.
  
  
  RESULTS
  Nineteen patients (10 women, 9 men; mean age, 63 years) harboring 19 bifurcation aneurysms (mean dome size, 8.8 mm; mean neck size, 5.8 mm) were included. Immediate angiographic outcome showed 11 complete aneurysm occlusions, 6 neck remnants, and 2 residual aneurysms. Follow-up at 6 months, obtained in all patients, included 12 complete aneurysm occlusions (63.1%), 6 neck remnants (31.6%), and 1 residual aneurysm (5.3%). Adequate occlusion (defined as complete occlusion and neck remnant combined) was observed in 94.7%. Progressive thrombosis was observed in 2 cases (10.6%) and recanalization in 1 case (5.3%). There was no in-stent stenosis or jailed branch occlusion. No bleeding was observed during the follow-up period. Permanent morbidity rate was 5.3% (1/19), and the mortality rate was 0% at 6 months.
  
  
  CONCLUSIONS
  The PulseRider allows endovascular treatment of wide-neck bifurcation intracranial aneurysms. Larger series are needed to confirm our preliminary results.
authors.affiliation: FHU IRIS, Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; University Claude Bernard Lyon 1, Lyon, France. Electronic address: benjamin.gory@chu-lyon.fr.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Gory
authors.affiliation: Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Alejandro M
authors.initials: AM
authors.lastname: Spiotta
authors.affiliation: Department of Neuroradiology, Ospedale Santa Maria, Treviso, Italy.
authors.forename: Franscesco
authors.initials: F
authors.lastname: Di Paola
authors.affiliation: Department of Neuroradiology, Careggi University Hospital, Firenze, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Mangiafico
authors.affiliation: Department of Neuroradiology, Careggi University Hospital, Firenze, Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Renieri
authors.affiliation: Department of Neuroradiology, Careggi University Hospital, Firenze, Italy.
authors.forename: Arturo
authors.initials: A
authors.lastname: Consoli
authors.affiliation: Department of Neuroradiology and Endovascular Therapy, Jean-Minjoz Hospital, Franche-Comté University, Besançon, France.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Biondi
authors.affiliation: FHU IRIS, Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France.
authors.forename: Roberto
authors.initials: R
authors.lastname: Riva
authors.affiliation: FHU IRIS, Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; University Claude Bernard Lyon 1, Lyon, France.
authors.forename: Paul-Emile
authors.initials: PE
authors.lastname: Labeyrie
authors.affiliation: FHU IRIS, Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; University Claude Bernard Lyon 1, Lyon, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Turjman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography; D057510:Endovascular Procedures / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000601:surgery*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
keywords: Intracranial aneurysms; Outcome; PulseRider; Stent-assisted coiling; Stenting