title: Comparison of Outcomes of Single-Level Anterior Cervical Discectomy With Fusion and Single-Level Artificial Cervical Disc Replacement for Single-Level Cervical Degenerative Disc Disease.
abstract: METHODS
  A single-center, prospective comparative study of prospectively collected outcomes, with a minimum 12 months follow-up.
  
  
  OBJECTIVE
  The primary purpose of the study is to investigate the clinical, functional, and radiological outcomes of cervical total disc replacement (CTDR) in comparison with anterior cervical discectomy and fusion (ACDF) in the treatment of single-level cervical disc degenerative disease, prospectively.
  
  
  BACKGROUND
  CTDR has recently been an alternative to ACDF in cervical disc degenerative disease to preserve the motion at the treated level.
  
  
  METHODS
  This study included 34 patients, who underwent either single-level ACDF (n = 17) or single-level CTDR (n = 17) at C3 to C7 level for cervical disc degenerative disease between July 2012 to April 2014 with a minimum of 12 months of follow-up.
  
  
  RESULTS
  Neck disability index, visual analog scale, and neck-arm pain score showed significant difference between the two groups at final follow-up of 12 months. Modified orthopedic association score and Nurick scale also showed the Japanese significant difference between the two groups at final follow-up of 12 months. Odom criteria were not statistically significant between the two groups at final follow-up. The changes in overall cervical sagittal angle (CSA) were significantly different between the two groups. The segmental angle (SA) was maintained at a significantly higher value in the CTDR group than in the ACDF group during the follow-up period (P < 0.05). The range of motion of the cervical spine and the treated level was well maintained and improved in the CTDR group as compared with ACDF group and showed extremely statistically significant difference between the two groups.
  
  
  CONCLUSIONS
  CTDR was found to be a safe, effective, better, and efficient alternative to the traditional ACDF. CTDR using Prestige LP cervical disc provided a statistically significant clinical, functional, and radiological outcomes between the two groups after 1-year follow-up.
  
  
  METHODS
  2.
authors.affiliation: Department of Orthopaedics, ESI-PGIMSR Model Hospital, New Delhi, New Delhi, India.
authors.forename: Praveen Kumar
authors.initials: PK
authors.lastname: Pandey
authors.affiliation: Department of Orthopaedics, ESI-PGIMSR Model Hospital, New Delhi, New Delhi, India.
authors.forename: Inder
authors.initials: I
authors.lastname: Pawar
authors.affiliation: Department of Anaesthesia, Dr. RML Hospital, New Delhi, New Delhi, India.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Gupta
authors.affiliation: Department of Orthopaedics, Dr. RML Hospital, New Delhi, New Delhi, India.
authors.forename: Raaghav Rai
authors.initials: RR
authors.lastname: Verma
mesh_terms: D000328:Adult; D002574:Cervical Vertebrae / Q000473:pathology / Q000601:surgery*; D017586:Diskectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology / Q000601:surgery*; D055959:Intervertebral Disc Degeneration / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016059:Range of Motion, Articular; D013123:Spinal Fusion / Q000379:methods*; D059145:Total Disc Replacement / Q000379:methods*; D016896:Treatment Outcome