title: Draft genome sequence of a multidrug-resistant beta-lactamase OXA-357-producing Acinetobacter pittii ST865 clinical isolate from China.
abstract: Worldwide increasing emergence of carbapenem-resistant Acinetobacter spp. has rendered the limited availability of effective antimicrobial agents and has become a major public health concern. In this study, we report the draft genome sequence of A. pittii TCM156, a multidrug-resistant isolate that harbored the blaOXA-357gene. The genome sequence was further analyzed by various bioinformatics methods. The genome size was estimated to be 3,807,313bp with 3508 predicted coding regions and G+C content is 38.7%. These findings have raised awareness of the possible emergence of OXA-type enzyme-producing A. pittii isolate in China.
authors.affiliation: The Affiliated Hospital of Hangzhou Normal University, Department of Respiratory Diseases, Hangzhou, Zhejiang, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Wang
authors.affiliation: The First Affiliated Hospital of Zhejiang Chinese Medical University, Department of General Practice, Hangzhou, Zhejiang, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.affiliation: The Affiliated Hospital of Hangzhou Normal University, Department of Respiratory Diseases, Hangzhou, Zhejiang, China.
authors.forename: Liyan
authors.initials: L
authors.lastname: Wu
authors.affiliation: The First Affiliated Hospital of Zhejiang Chinese Medical University, Department of General Practice, Hangzhou, Zhejiang, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.affiliation: The Affiliated Hospital of Hangzhou Normal University, Department of Emergency Medicine, Hangzhou, Zhejiang, China. Electronic address: swallowchen120@163.com.
authors.forename: Liqun
authors.initials: L
authors.lastname: Xu
mesh_terms: D000150:Acinetobacter / Q000187:drug effects / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D000151:Acinetobacter Infections / Q000382:microbiology*; D001482:Base Composition; D002681:China; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D016680:Genome, Bacterial; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; D001618:beta-Lactamases
keywords: Acinetobacter pittii; Multidrug-resistance; Whole genome sequencing (WGS); bla(OXA-357)