title: Anaphylactic reaction secondary to topical preoperative moxifloxacin.
abstract: We report a case of anaphylactic shock following topical administration of moxifloxacin for endophthalmitis prophylaxis prior to cataract surgery. Immunoglobulin E (IgE) serology and IgE skin testing confirmed the anaphylactic etiology. Phacoemulsification with posterior chamber intraocular lens implantation was later performed with identical preoperative preparation except for the exclusion of moxifloxacin; no anaphylactic response occurred. To our knowledge, this is the first report of an anaphylactic response to topical moxifloxacin.
  
  
  
  None of the authors has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Department of Ophthalmology (M.A. Ullman, Midgley, Kim), MedStar Washington Hospital Center, and the Department of Ophthalmology (M.A.Ullman, Midgley, Kim), MedStar Georgetown University Hospital, Washington, DC; Ullman Eye Consultants (S. Ullman), Pensacola, Florida, USA. Electronic address: mullman@gmail.com.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Ullman
authors.affiliation: From the Department of Ophthalmology (M.A. Ullman, Midgley, Kim), MedStar Washington Hospital Center, and the Department of Ophthalmology (M.A.Ullman, Midgley, Kim), MedStar Georgetown University Hospital, Washington, DC; Ullman Eye Consultants (S. Ullman), Pensacola, Florida, USA.
authors.forename: Kirsten J
authors.initials: KJ
authors.lastname: Midgley
authors.affiliation: From the Department of Ophthalmology (M.A. Ullman, Midgley, Kim), MedStar Washington Hospital Center, and the Department of Ophthalmology (M.A.Ullman, Midgley, Kim), MedStar Georgetown University Hospital, Washington, DC; Ullman Eye Consultants (S. Ullman), Pensacola, Florida, USA.
authors.forename: Jocelyn
authors.initials: J
authors.lastname: Kim
authors.affiliation: From the Department of Ophthalmology (M.A. Ullman, Midgley, Kim), MedStar Washington Hospital Center, and the Department of Ophthalmology (M.A.Ullman, Midgley, Kim), MedStar Georgetown University Hospital, Washington, DC; Ullman Eye Consultants (S. Ullman), Pensacola, Florida, USA.
authors.forename: Saul
authors.initials: S
authors.lastname: Ullman
mesh_terms: D000369:Aged, 80 and over; D000707:Anaphylaxis / Q000139:chemically induced*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D024841:Fluoroquinolones / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D019654:Lens Implantation, Intraocular; D000077266:Moxifloxacin; D018918:Phacoemulsification
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D000077266:Moxifloxacin