title: [Long non-coding RNA and wound healing].
abstract: Long non-coding RNA (lncRNA) is a class of RNA molecules longer than 200 nucleotides which does not encode proteins or only encode a few proteins, and it plays important regulatory roles in the expression of genes at the epigenetic, transcriptional, and posttranscriptional levels. The recent reports suggest that lncRNA plays a significant role in growth and development of body, cellular biological processes including in cell proliferation, differentiation, migration, and apoptosis, and regulation of wound healing processes such as re-epithelialization, angiogenesis, and scar formation. The lncRNA has become a new research hotspot in wound healing. This article reviews the role of lncRNA in different stages of wound repair to get a further understanding of molecular mechanisms of wound healing and provide a new target spot for prevention and treatment of pathological scars and wound healing.
authors.affiliation: Department of Burns, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: D W
authors.initials: DW
authors.lastname: Liu
mesh_terms: D017209:Apoptosis / Q000235:genetics; D002454:Cell Differentiation / Q000235:genetics; D002465:Cell Movement / Q000235:genetics; D049109:Cell Proliferation / Q000235:genetics; D002921:Cicatrix; D006801:Humans; D062085:RNA, Long Noncoding; D062326:Re-Epithelialization; D014945:Wound Healing / Q000235:genetics*
chemical_list: D062085:RNA, Long Noncoding