title: Reply.
authors.affiliation: Division of Clinical Genomics, Ambry Genetics, Aliso Viejo, CA.
authors.forename: Katherine L
authors.identifier: 0000-0001-8249-0549
authors.initials: KL
authors.lastname: Helbig
authors.affiliation: Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
authors.forename: Ulrike B S
authors.initials: UB
authors.lastname: Hedrich
authors.affiliation: Department of Medicine, Epilepsy Research Centre, Austin Health, University of Melbourne, Heidelberg, Victoria, Australia.|Florey Institute of Neurosciences and Mental Health, Melbourne, Victoria, Australia.|Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Parkville, Victoria, Australia.
authors.forename: Ingrid E
authors.initials: IE
authors.lastname: Scheffer
authors.affiliation: Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA.|Department of Neuropediatrics, University Medical Center Schleswig-Holstein, Department of Neuropediatrics, University of Kiel, Kiel, Germany.
authors.forename: Ingo
authors.initials: I
authors.lastname: Helbig
authors.affiliation: Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
authors.forename: Holger
authors.initials: H
authors.lastname: Lerche
authors.affiliation: Institute of Human Genetics, University of Leipzig Hospitals and Clinics, Leipzig, Germany.
authors.forename: Johannes R
authors.initials: JR
authors.lastname: Lemke
mesh_terms: D006801:Humans; D009154:Mutation; D015419:Spastic Paraplegia, Hereditary