title: μ-ViP: Customized virtual phantom for quantitative magnetic resonance micro-imaging at high magnetic field.
abstract: The applications of Magnetic Resonance micro-Imaging (MRμI) cover nowadays a wide range of fields. However few of them present quantitative measurements when the sample of interest changes over time or in case of a long acquisition time. In this domain, two challenges have to be overcome: the introduction of a phantom as a reference signal and the guarantee that this signal is stable over the experiment duration while some conditions such as temperature and/or the moisture are varied. The aim of the present study was to implement a dedicated experimental set-up to generate a virtual phantom (ViP) signal in a vertical-bore 11.7 T NMR spectrometer, equipped with a micro-imaging probe. This study shows that the generation of a micro-imaging-dedicated ViP (μ-ViP) signal is of great benefit for on-line quality control of the spectrometer performance during acquisition in the case of real-time experiments. Thus, μViP represents a step towards improvement of the magnetic resonance signal quantification in small samples.
authors.affiliation: Irstea, UR OPAALE, 17 avenue de Cucillé, CS 64427, F-35044 Rennes, France; Université Bretagne Loire, France. Electronic address: corinne.rondeau@irstea.fr.
authors.forename: C
authors.initials: C
authors.lastname: Rondeau-Mouro
authors.affiliation: Irstea, UR OPAALE, 17 avenue de Cucillé, CS 64427, F-35044 Rennes, France; Université Bretagne Loire, France.
authors.forename: R
authors.initials: R
authors.lastname: Kovrlija
authors.affiliation: INSERM, UMR 1099, Rennes, France; LTSI, Université de Rennes 1, 35000 Rennes, France.
authors.forename: G
authors.initials: G
authors.lastname: Gambarota
authors.affiliation: INSERM, UMR 1099, Rennes, France; LTSI, Université de Rennes 1, 35000 Rennes, France; CRLCC, Centre Eugène Marquis, Rennes, France.
authors.forename: H
authors.initials: H
authors.lastname: Saint-Jalmes
keywords: MRI; MRμI; Reference signal; Virtual phantom