title: Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia.
authors.affiliation: Division of Hematology/Oncology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Seethal A
authors.identifier: 0000-0003-2906-6102
authors.initials: SA
authors.lastname: Jacob
authors.affiliation: Division of Hematology-Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania.|Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Enrico M
authors.initials: EM
authors.lastname: Novelli
authors.affiliation: Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.|Pulmonary, Allergy, Critical Care Medicine Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Isenberg
authors.affiliation: Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.
authors.forename: Melanie E
authors.initials: ME
authors.lastname: Garrett
authors.affiliation: Pulmonary, Allergy, Critical Care Medicine Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Chu
authors.affiliation: Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.
authors.forename: Karen
authors.initials: K
authors.lastname: Soldano
authors.affiliation: Division of Hematology/Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
authors.forename: Kenneth I
authors.initials: KI
authors.lastname: Ataga
authors.affiliation: Division of Hematology, Department of Medicine, and Duke Comprehensive Sickle Cell Center, Duke University Medical Center, Durham, North Carolina.
authors.forename: Marilyn J
authors.initials: MJ
authors.lastname: Telen
authors.affiliation: Duke Molecular Physiology Institute, Duke University Medical Center, Durham, North Carolina.
authors.forename: Allison
authors.initials: A
authors.lastname: Ashley-Koch
authors.affiliation: Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.|Pulmonary, Allergy, Critical Care Medicine Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Mark T
authors.initials: MT
authors.lastname: Gladwin
authors.affiliation: Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.|Pulmonary, Allergy, Critical Care Medicine Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.|Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Yingze
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Division of Hematology-Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania.|Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Gregory J
authors.identifier: 0000-0003-4465-3217
authors.initials: GJ
authors.lastname: Kato
mesh_terms: D000755:Anemia, Sickle Cell / Q000235:genetics / Q000503:physiopathology; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000235:genetics / Q000503:physiopathology; D008297:Male; D020641:Polymorphism, Single Nucleotide; D011651:Pulmonary Artery / Q000503:physiopathology*; D019700:Thrombospondin 1 / Q000235:genetics*
chemical_list: D019700:Thrombospondin 1; C000611726:thrombospondin-1, human