title: Short-term effect of scalpel debridement of plantar callosities versus treatment with salicylic acid patches: The EMEDESCA randomized controlled trial.
abstract: This study compares scalpel debridement versus salicylic acid patches in the treatment of plantar callosities. A randomized clinical trial (ACTRN12614000591651) was performed with 62 patients, divided into two intervention groups. Group A received treatment with salicylic acid patches (Callívoro Marthand®) and group B underwent scalpel debridement of plantar callosities. Pain was measured on a visual analog scale, and foot pain and disability were evaluated using the Manchester Foot Pain Disability Index (MFPDI) questionnaire (Spanish version). Significant differences were observed in pain measured immediately after treatment (P < 0.001) and at 15 days and 6 weeks after treatment. For some components, the MFPDI questionnaire revealed significantly better outcomes by scalpel debridement at 15 days after treatment. The scalpel debridement of plantar callosities relieves pain more effectively than salicylic acid patches, and patients achieve greater functionality in the initial weeks after debridement.
authors.affiliation: Department of Nursing and Podiatry, University of Málaga, Malaga, Spain.
authors.forename: Gabriel
authors.identifier: http://orcid.org/0000-0002-7692-7756
authors.initials: G
authors.lastname: Gijón-Noguerón
authors.affiliation: Department of Nursing and Podiatry, University of Málaga, Malaga, Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: García-Paya
authors.affiliation: Department of Nursing and Podiatry, University of Málaga, Malaga, Spain.
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Morales-Asencio
authors.affiliation: Department of Nursing and Podiatry, University of Málaga, Malaga, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Jiménez-Cebrián
authors.affiliation: Department of Nursing and Podiatry, University of Málaga, Malaga, Spain.
authors.forename: Ana Belén
authors.initials: AB
authors.lastname: Ortega-Ávila
authors.affiliation: Department of Nursing and Podiatry, University of Málaga, Malaga, Spain.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Cervera-Marín
mesh_terms: D000328:Adult; D002145:Callosities / Q000188:drug therapy* / Q000601:surgery*; D003646:Debridement / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D020156:Salicylic Acid / Q000008:administration & dosage*
chemical_list: D007641:Keratolytic Agents; D020156:Salicylic Acid
keywords: callosities; calluses; elimination; pain; skin