title: The muscle biopsy technique. Historical and methodological considerations.
abstract: The muscle biopsy method is an important tool for clinical and scientific work. In this study, the two most used instruments, the Bergström needle and the Well-Blakesley conchotome, are described. The technique of using those instruments, risks, and other considerations are discussed. Finally, a few consequences and the error of the method for determining muscle fiber type, fiber area, substrates, and metabolites are presented.
authors.affiliation: Åstrand Laboratory, The Swedish School of Sport and Health Sciences, Stockholm, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Ekblom
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000473:pathology*; D009135:Muscular Diseases / Q000473:pathology; D013396:Suction / Q000379:methods*
keywords: Bergström needle; Well-Blakesley conchotome; consequences; methodological error