title: Anti-MDA5 dermatomyositis mimicking psoriatic arthritis.
abstract: Dermatomyositis causes inflammation and damage of muscle and skin, and sometimes involves internal organs, especially lung parenchyma. Patients with dermatomyositis still represent a diagnostic challenge because of the rarity of this disease and the lack of specificity of some of its cutaneous manifestations. Herein, we describe the case of a patient with dermatomyositis, initially diagnosed as psoriatic arthritis, in which the performance of anti-melanoma differentiation-associated gene 5 (MDA5) antibodies was decisive to establish a definitive diagnosis.
authors.affiliation: Servicio de Reumatología, Hospital Universitario Central de Asturias, Oviedo, Spain. Electronic address: icaro231@gmail.com.
authors.forename: Iván
authors.initials: I
authors.lastname: Cabezas-Rodríguez
authors.affiliation: Servicio de Reumatología, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Isla
authors.initials: I
authors.lastname: Morante-Bolado
authors.affiliation: Servicio de Reumatología, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Anahy
authors.initials: A
authors.lastname: Brandy-García
authors.affiliation: Servicio de Reumatología, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Rubén
authors.initials: R
authors.lastname: Queiro-Silva
authors.affiliation: Servicio de Inmunología, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Lourdes
authors.initials: L
authors.lastname: Mozo
authors.affiliation: Servicio de Reumatología, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Ballina-García
mesh_terms: D000328:Adult; D015535:Arthritis, Psoriatic / Q000175:diagnosis*; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D003882:Dermatomyositis / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D000072640:Interferon-Induced Helicase, IFIH1 / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; C452815:IFIH1 protein, human; D000072640:Interferon-Induced Helicase, IFIH1
keywords: Artritis psoriásica; Dermatomiositis; Dermatomyositis; Melanoma differentiation-associated protein gene 5; Proteína asociada a la diferenciación del melanoma 5; Psoriatic arthritis