title: Outcome, Prognostic Factors, and Follow-Up Results After Subarachnoid Hemorrhage from Pericallosal Artery Aneurysms.
abstract: OBJECTIVE
  Pericallosal artery aneurysms (PAAs) are usually rare (2%-5%), and treatment is challenging for both surgical and endovascular modalities. We performed this analysis to determine the outcome and prognostic factors after subarachnoidal hemorrhage (SAH) caused by ruptured PAAs.
  
  
  METHODS
  A total of 32 patients with ruptured PAA were admitted to our hospital between 1999 and 2014, added to our prospective database, and analyzed retrospectively. Outcome was measured based on the modified Rankin Scale (mRS) at 6 months after ictus (favorable mRS score, 0-2 vs. unfavorable mRS score, 3-6).
  
  
  RESULTS
  Only 16 (50%) patients had a good clinical status at admission (World Federation of Neurological Surgeons Grading System [WFNS] grades I-III), whereas 12 patients (37.5%) were comatose (WFNS grade V). In 18 patients (56%), intracerebral hemorrhage was confirmed, in 18 patients (56%) cerebrospinal fluid drainage was required immediately after admission, and in 5 cases (16%) decompressive craniectomy was performed. There were 17 patients (53.1%) who achieved a favorable outcome (mRS score 0-2) at follow-up. Unfavorable outcome was associated with smoking, cerebral infarction, and worse admission status after multiple logistic regression analysis.
  
  
  CONCLUSIONS
  Poor admission status, cerebral infarction, and smoking seem to be crucial factors for unfavorable outcome after SAH from PAA.
authors.affiliation: Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany. Electronic address: dinc.nazife@gmail.com.
authors.forename: Nazife
authors.initials: N
authors.lastname: Dinc
authors.affiliation: Department of Neuroradiology, Goethe University Hospital, Frankfurt, Germany.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Lescher
authors.affiliation: Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany.
authors.forename: Johanna
authors.initials: J
authors.lastname: Quick-Weller
authors.affiliation: Department of Neuroradiology, Goethe University Hospital, Frankfurt, Germany.
authors.forename: Joachim
authors.initials: J
authors.lastname: Berkefeld
authors.affiliation: Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Platz
authors.affiliation: Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Senft
authors.affiliation: Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany.
authors.forename: Volker
authors.initials: V
authors.lastname: Seifert
authors.affiliation: Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany.
authors.forename: Juergen
authors.initials: J
authors.lastname: Konczalla
mesh_terms: D000328:Adult; D017542:Aneurysm, Ruptured / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D020771:Anterior Cerebral Artery / Q000601:surgery*; D002543:Cerebral Hemorrhage / Q000453:epidemiology; D002544:Cerebral Infarction / Q000453:epidemiology; D003337:Corpus Callosum / Q000098:blood supply*; D056424:Decompressive Craniectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012907:Smoking / Q000453:epidemiology; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D020301:Vasospasm, Intracranial / Q000453:epidemiology
keywords: A. pericallosal aneurysm; Cigarette use; Clipping; Endovascular treatment; Prognostic factors; Subarachnoidal hemorrhage