title: Multiple Eccrine Syringofibroadenoma of Mascaro of the Lower Extremity.
abstract: Eccrine syringofibroadenoma (ESFA) is a rare benign lesion of ductal and secretory differentiation exhibiting multiple cutaneous polymorphic presentations with an unknown etiology. We present a case of ESFA that uniquely exhibited large, thick, verrucous-like hyperplastic growths as well as superficial shiny mosaic plaques and deep ulcerations in three different anatomical locations in the same patient. The diagnosis of ESFA was confirmed histologically after biopsies were performed on all of the affected areas. In addition to a case report and literature review, we also present classification, clinical, and histologic aspects of ESFA.
authors.forename: Danae L
authors.initials: DL
authors.lastname: Lowell
authors.forename: Nichol L
authors.initials: NL
authors.lastname: Salvo
authors.forename: William J
authors.initials: WJ
authors.lastname: Weily
authors.forename: Michael
authors.initials: M
authors.lastname: Swiatek
authors.forename: Hannah
authors.initials: H
authors.lastname: Sahli
mesh_terms: D006607:Adenoma, Sweat Gland / Q000473:pathology* / Q000601:surgery; D000671:Amputation, Surgical / Q000379:methods*; D001707:Biopsy, Needle; D005500:Follow-Up Studies; D006365:Heel / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D035002:Lower Extremity / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D018570:Risk Assessment; D013544:Sweat Gland Neoplasms / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome