title: The association between mental health problems and menstrual cycle irregularity among adolescent Korean girls.
abstract: Menstrual cycle irregularity is common among adolescents and can induce mental health problems such as stress, depression, and suicidal ideation. We examined the association between mental health problems and menstrual cycle irregularity among adolescent Korean girls.
  
  
  
  This population-based cross-sectional study was on 808 female adolescents (12-18 years of age) participating in the 2010-2012 Korean National Health and Nutrition Examination Survey. Psychological stress, depressive mood, suicidal ideations, suicide attempts, and psychological counseling were assessed through questionnaires and surveys, and hierarchical multivariable logistic regression analysis was performed.
  
  
  
  The risk of menstrual cycle irregularity tended to increase, as the number of mental health problems increased (P for trend=0.016). High stress levels, depressive mood, and psychological counseling were associated with increased risks of menstrual cycle irregularity (odd ratio [95% confidence interval]=1.88 [1.1-3.21], 2.01 [1.01-4.03], and 2.92 [1.16-7.34], respectively) even after adjusting for age, body mass index, alcohol consumption, smoking status, physical activity, hemoglobin level, monthly household income, weight loss attempts, age at menarche, and sleep duration. Suicidal ideation was not significantly associated with menstrual cycle irregularity.
  
  
  
  Menstrual irregularity was evaluated based solely on subjects' self-reports, which are subject to their subjective perceptions and appraisal. Cross-sectional design and retrospective data could not draw causal relationship.
  
  
  
  Positive associations were observed between mental health problems and menstrual cycle irregularity among adolescent Korean girls. More attention should be paid towards mental health, to improve menstrual cycle regularity and help prevent related chronic diseases later in life.
authors.affiliation: College of Nursing, Institute of Health Sciences, Gyeongsang National University, Jinju-si, Republic of Korea.
authors.forename: Mi
authors.initials: M
authors.lastname: Yu
authors.affiliation: Department of Biostatistics, College of Medicine, Catholic University, Seoul, Republic of Korea.
authors.forename: Kyungdo
authors.initials: K
authors.lastname: Han
authors.affiliation: Department of Family Medicine, Sahmyook Medical Center, Seoul, Republic of Korea. Electronic address: namgaaa@hanmail.net.
authors.forename: Ga Eun
authors.initials: GE
authors.lastname: Nam
mesh_terms: D000293:Adolescent; D002648:Child; D003376:Counseling; D003430:Cross-Sectional Studies; D003863:Depression / Q000523:psychology; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000523:psychology*; D008599:Menstruation Disturbances / Q000523:psychology*; D001523:Mental Disorders / Q000453:epidemiology* / Q000523:psychology*; D008603:Mental Health; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D013315:Stress, Psychological / Q000523:psychology; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires