title: Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reducedin vivohoming capacity compared to plerixafor alone.
authors.affiliation: San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.|Vita-Salute San Raffaele University, Milan, Italy.
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Lidonnici
authors.affiliation: San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.|Università degli Studi di Roma "Tor Vergata", Italy.
authors.forename: Annamaria
authors.initials: A
authors.lastname: Aprile
authors.affiliation: Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Marta Claudia
authors.initials: MC
authors.lastname: Frittoli
authors.affiliation: San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Mandelli
authors.affiliation: San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy.|Vita-Salute San Raffaele University, Milan, Italy.
authors.forename: Ylenia
authors.initials: Y
authors.lastname: Paleari
authors.affiliation: Experimental Imaging Centre, San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Antonello
authors.initials: A
authors.lastname: Spinelli
authors.affiliation: Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Gentner
authors.affiliation: Immunohematology and Transfusion Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Matilde
authors.initials: M
authors.lastname: Zambelli
authors.affiliation: Immunohematology and Transfusion Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Cristina
authors.initials: C
authors.lastname: Parisi
authors.affiliation: Immunohematology and Transfusion Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Bellio
authors.affiliation: Università di Milano, Ca Granda Foundation IRCCS, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Cassinerio
authors.affiliation: Università di Milano, Ca Granda Foundation IRCCS, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Zanaboni
authors.affiliation: Università di Milano, Ca Granda Foundation IRCCS, Italy.
authors.forename: Maria Domenica
authors.initials: MD
authors.lastname: Cappellini
authors.affiliation: Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Ciceri
authors.affiliation: Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Sarah
authors.initials: S
authors.lastname: Marktel
authors.affiliation: San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), Division of Regenerative Medicine, Stem Cells and Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy ferrari.giuliana@hsr.it.|Vita-Salute San Raffaele University, Milan, Italy.
authors.forename: Giuliana
authors.initials: G
authors.lastname: Ferrari
mesh_terms: D000818:Animals; D018952:Antigens, CD34 / Q000235:genetics / Q000276:immunology; D001596:Benzylamines; D018797:Cell Cycle Proteins / Q000235:genetics / Q000276:immunology; D054377:Chemokine CXCL12 / Q000235:genetics* / Q000276:immunology; D000080027:Cyclams; D004338:Drug Combinations; D004720:Endonucleases / Q000235:genetics / Q000276:immunology; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000276:immunology; D006571:Heterocyclic Compounds / Q000494:pharmacology*; D006801:Humans; D016130:Immunophenotyping; D007937:Leukapheresis; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000276:immunology; D051379:Mice; D011485:Protein Binding; D019718:Receptors, CXCR4 / Q000235:genetics* / Q000276:immunology; D015398:Signal Transduction; D055153:Stem Cell Niche / Q000276:immunology*; D017086:beta-Thalassemia / Q000235:genetics / Q000276:immunology / Q000473:pathology / Q000628:therapy
chemical_list: D018952:Antigens, CD34; D001596:Benzylamines; C515255:CXCL12 protein, human; C527276:CXCR4 protein, human; D018797:Cell Cycle Proteins; D054377:Chemokine CXCL12; D000080027:Cyclams; D004338:Drug Combinations; D006571:Heterocyclic Compounds; D019718:Receptors, CXCR4; D016179:Granulocyte Colony-Stimulating Factor; D004720:Endonucleases; C088327:plerixafor