title: Commiphoranes A-D, Carbon Skeletal Terpenoids from Resina Commiphora.
abstract: Commiphoranes A-D (1-4), four novel aromatic terpenoids with unprecedented carbon skeletons, were isolated from Resina Commiphora. Their structures were identified by spectroscopic and crystallographic methods. Compounds 1 and 2 are dinorditerpenoids characteristic of a 6/6/6/6 ring system. In contrast, compounds 3 and 4 are sesquiterpenoids possessing a 5/6/7 backbone. Biological evaluation reveals that 3 could significantly attenuate overproduction of fibronectin, collagen I, and α-SMA in TGF-β1-induced rat renal proximal tubular cells.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, PR China.|Guangdong Pharmaceutical University , Guangzhou 510006, PR China.
authors.forename: Lu
authors.initials: L
authors.lastname: Dong
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, PR China.|Guangdong Pharmaceutical University , Guangzhou 510006, PR China.
authors.forename: Li-Zhi
authors.initials: LZ
authors.lastname: Cheng
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, PR China.
authors.forename: Yong-Ming
authors.initials: YM
authors.lastname: Yan
authors.affiliation: Guangdong Pharmaceutical University , Guangzhou 510006, PR China.
authors.forename: Shu-Mei
authors.initials: SM
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, PR China.
authors.forename: Yong-Xian
authors.identifier: 0000-0002-1343-0806
authors.initials: YX
authors.lastname: Cheng