title: Analysis of Consequences of Birth Asphyxia in Infants: A Regional Study in Southern Punjab, Pakistan.
abstract: OBJECTIVE
  To evaluate the biochemical consequences and platelet counts of birth asphyxia in neonates.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  Department of Child Health, Nishter Medical College and Hospital, Multan, from September to November 2015.
  
  
  METHODS
  The data of 50 (50%) asphyxiated neonates and 50 (50%) non-asphyxiated neonates, with age range less than 1 month, was collected from Children Ward of Nishtar Hospital, Multan, Pakistan. Data on platelet count in blood, kidney function tests (creatinine, urea), liver function tests (bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST)) and cardiac enzyme test (lactate dehydrogenase (LDH)) were analysed by paired sample t-test by SPSS software. Sociodemographic data of those neonate's mothers was also collected.
  
  
  RESULTS
  In asphyxiated neonates LDH, ALT, AST, creatinine, bilirubin, urea levels were higher than healthy infants, while the platelet count was smaller in asphyxiated neonates than healthy infants.
  
  
  CONCLUSIONS
  There was a higher rate of alteration in platelet count, levels of LDH, AST, ALT, urea creatinine and bilirubin in asphyxiated infants. These alterations may be correlated with damage of vital organ of asphyxiated neonates.
authors.affiliation: Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
authors.forename: Noreen
authors.initials: N
authors.lastname: Samad
authors.affiliation: Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
authors.forename: Samia
authors.initials: S
authors.lastname: Farooq
authors.affiliation: Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
authors.forename: Kinza
authors.initials: K
authors.lastname: Hafeez
authors.affiliation: Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
authors.forename: Mukharma
authors.initials: M
authors.lastname: Maryam
authors.affiliation: Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
authors.forename: Muhammad Aftab
authors.initials: MA
authors.lastname: Rafi
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001238:Asphyxia Neonatorum / Q000097:blood* / Q000201:enzymology* / Q000453:epidemiology; D001663:Bilirubin / Q000097:blood; D015415:Biomarkers / Q000097:blood*; D016022:Case-Control Studies; D015331:Cohort Studies; D003404:Creatinine / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D007677:Kidney Function Tests; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008111:Liver Function Tests; D010154:Pakistan / Q000453:epidemiology; D010976:Platelet Count / Q000706:statistics & numerical data*
chemical_list: D015415:Biomarkers; D003404:Creatinine; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin