title: Wilms Tumor With Metastasis to the Vagina: A Case Report.
abstract: A 12-year-old female presented with abdominal pain, night sweats, weight loss, constipation, dysmenorrhea, menorrhagia, and vaginal discharge. Examination revealed a palpable flank mass and a large tumor adherent to the anterior vaginal wall. Computed tomography scan demonstrated a 23 cm mass in the left kidney, a separate 10.8 cm pelvic mass, and metastatic disease. Biopsies were consistent with Wilms tumor. Neoadjuvant chemotherapy and a left radical nephrectomy were performed for her stage IV disease as the kidney was amiable to complete resection. The patient received radiation and resumed chemotherapy. She was doing well with improved symptoms at follow-up.
authors.affiliation: Division of Pediatric Urology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY; Division of Pediatric Gynecology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY. Electronic address: adamo.howe@gmail.com.
authors.forename: Adam S
authors.initials: AS
authors.lastname: Howe
authors.affiliation: Division of Pediatric Urology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY.
authors.forename: Bradley A
authors.initials: BA
authors.lastname: Morganstern
authors.affiliation: Division of Pediatric Gynecology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY.
authors.forename: Heather
authors.initials: H
authors.lastname: Appelbaum
authors.affiliation: Division of Pediatric Urology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Mehta
authors.affiliation: Division of Pediatric Urology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY.
authors.forename: Lane S
authors.initials: LS
authors.lastname: Palmer
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D002648:Child; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000628:therapy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D009362:Neoplasm Metastasis; D009392:Nephrectomy / Q000379:methods; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed; D014625:Vaginal Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D009396:Wilms Tumor / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents