title: Bioresorbable coronary stent for the treatment of complex coronary lesions: Data from an all-comer registry.
abstract: BACKGROUND
  The study aimed to report the results from an all-comers registry of patients undergoing coronary angioplasty and treated with bioresorbable vascular scaffold (BVS).
  
  
  METHODS
  Fifty-five consecutive patients with type B/C coronary lesions according to the AHA classification and treated with BVS were enrolled in the study. The clinical and procedural characteristics of enrolled patients were recorded. Fifty-five consecutive subjects with coronary lesions type B/C treated with everolimus eluting stent (EES) were used as control group.
  
  
  RESULTS
  The incidence of adverse events was not statistically significant comparing subjects treated with BVS with those treated with EES. Non significant differences were also found in the follow-up considering the presence of diabetes, multivessel disease, use of more than one stent at the same time, diagnosis (STEMI vs UA/NSTEMI), use of coronary stents in overlapping. The differences were significant considering the type of lesion (Log-Rank p<0.05), stenoses treated in correspondence of a coronary bifurcation (p<0.05), the SYNTAX score (cut off 22) (p<0.001); after multivariable correction for age and gender, however, differences remained significant only for SYNTAX score.
  
  
  CONCLUSIONS
  The use of BVS in an all-comers registry of patients undergoing coronary angioplasty on complex coronary lesions is associated with a safety profile comparable to that obtained with EES; the use of BVS in particular conditions, such as very high SYNTAX score, should be further assessed.
authors.affiliation: Cardiology Departement, Ospedali Riuniti University Hospital, Foggia, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Cuculo
authors.affiliation: Cardiology Departement, Ospedali Riuniti University Hospital, Foggia, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Ruggiero
authors.affiliation: Cardiology Departement, Ospedali Riuniti University Hospital, Foggia, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Centola
authors.affiliation: Cardiology Departement, Ospedali Riuniti University Hospital, Foggia, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Campanale
authors.affiliation: Department of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Passero
authors.affiliation: Department of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Gaglione
authors.affiliation: Cardiology Departement, Ospedali Riuniti University Hospital, Foggia, Italy; Department of Medical & Surgical Sciences, University of Foggia, Foggia, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Di Biase
authors.affiliation: Department of Medical & Surgical Sciences, University of Foggia, Foggia, Italy. Electronic address: natale.brunetti@unifg.it.
authors.forename: Natale Daniele
authors.initials: ND
authors.lastname: Brunetti
mesh_terms: D020341:Absorbable Implants; D000368:Aged; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000601:surgery*; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000601:surgery*; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D011474:Prosthesis Design; D012042:Registries; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends; D016896:Treatment Outcome
keywords: Bioresorbable coronary stent; Complex coronary lesions; Coronary angioplasty; Everolimus eluting stent