title: Ambient fine and coarse particulate matter pollution and respiratory morbidity in Dongguan, China.
abstract: We estimated the short-term effects of particulate matter (PM) pollution with aerodynamic diameters ≤2.5 μm (PM2.5) and between 2.5 and 10 μm (PMc) on hospital outpatient visits due to overall and specific respiratory diseases, as well as the associated morbidity burden in Dongguan, a subtropical city in South China. A time-series model with quasi-Poisson link was used to examine the association between PM pollution and morbidities from respiratory diseases, COPD, asthma and pneumonia in Dongguan during 2013-2015. We further estimated the morbidity burden (population attributable fraction and attributable morbidity) due to ambient PM pollution. A total of 44,801 hospital outpatient visits for respiratory diseases were recorded during the study period. Both PM2.5and PMcwere found to be significantly associated with morbidity of overall respiratory diseases, COPD, and asthma. An IQR (interquartile range) increase in PM2.5at lag03day was associated with 15.41% (95% CI: 10.99%, 20.01%) increase in respiratory morbidity, and each IQR increase in PMcat lag03corresponded to 7.24% (95% CI: 4.25%, 10.32%) increase in respiratory morbidity. We did not find significant effects of PM2.5and PMcon pneumonia. Using WHO's guideline (25 μg/m3) as reference concentration, about 8.32% (95% CI: 5.90%, 10.86%) of respiratory morbidity (3727, 95% CI: 2642, 4867, in morbidity number) were estimated to be attributed to PM2.5, and 0.86% (95% CI: 0.50%, 1.23%) of respiratory morbidity, representing 385 (95% CI: 225, 551) hospital outpatient visits, could be attributed to coarse particulate pollutant. Our study suggests that both fine and coarse particulate pollutants are an important trigger of hospital outpatient visits for respiratory diseases, and account for substantial respiratory morbidity in Dongguan, China.
authors.affiliation: Department of Respirator Medicine, The Fifth People's Hospital of Dongguan, Dongguan, China.
authors.forename: Yiju
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Medical College, Jinan University, Guangzhou, China.
authors.forename: Shengyong
authors.initials: S
authors.lastname: Wang
authors.affiliation: Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Lang
authors.affiliation: Department of Respirator Medicine, The Fifth People's Hospital of Dongguan, Dongguan, China.
authors.forename: Caiyan
authors.initials: C
authors.lastname: Huang
authors.affiliation: Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China. Electronic address: mawj@gdiph.org.cn.
authors.forename: Wenjun
authors.initials: W
authors.lastname: Ma
authors.affiliation: Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China. Electronic address: linhualiang2002@163.com.
authors.forename: Hualiang
authors.initials: H
authors.lastname: Lin
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis*; D000397:Air Pollution / Q000009:adverse effects* / Q000032:analysis; D001249:Asthma / Q000139:chemically induced / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008962:Models, Theoretical; D010316:Particle Size; D052638:Particulate Matter / Q000009:adverse effects / Q000032:analysis*; D011634:Public Health; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000453:epidemiology*; D013997:Time Factors
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter
keywords: Coarse particle; Disease burden; Fine particle; Morbidity