title: Astigmatism Correction With Toric Intraocular Lenses in Descemet Membrane Endothelial Keratoplasty Triple Procedures.
abstract: OBJECTIVE
  To report the clinical efficacy of astigmatism correction with toric intraocular lenses (IOLs) in patients undergoing the Descemet membrane endothelial keratoplasty (DMEK) triple procedure and to evaluate the accuracy of the correction.
  
  
  METHODS
  Fifteen eyes of 10 patients who received cataract extraction, toric IOL placement, and DMEK surgery for Fuchs corneal dystrophy and cataracts were evaluated. The cylinder power of toric IOLs was determined by an online toric calculator with keratoscopy measurements obtained using Scheimpflug corneal imaging. Prediction errors were assessed as a difference vector between the anticipated minus postoperative residual astigmatism.
  
  
  RESULTS
  At 10.1 ± 4.9 months postoperatively, 8/13 (61.5%) of eyes achieved uncorrected distance visual acuity better than 20/40. Mean best spectacle-corrected distance visual acuity (logMAR) improved from 0.21 ± 0.15 preoperatively to 0.08 ± 0.12 postoperatively (P < 0.01). The magnitude of refractive astigmatism was also significantly decreased from 2.23 ± 1.10 D (range 0.75-4.25 D) preoperatively to 0.87 ± 0.75 D (range 0.00-3.00 D) postoperatively (P < 0.01). In 1 eye with rotational misalignment by 43 degrees, we found no improvement of astigmatism. The prediction error of astigmatism at the corneal plane was 0.77 ± 0.54 D (range 0.10-1.77 D). Four eyes with preoperative "with-the-rule" corneal astigmatism had postoperative "against-the-rule" refractive astigmatism.
  
  
  CONCLUSIONS
  For patients with Fuchs corneal dystrophy and cataracts, use of toric IOLs might be a valuable option in triple DMEK surgery. Additionally, care should be taken to prevent excessive IOL rotation.
authors.affiliation: *Cornea Service, Devers Eye Institute, Portland, OR; †Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; and ‡Lions VisionGift, Portland, OR.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yokogawa
authors.forename: P James
authors.initials: PJ
authors.lastname: Sanchez
authors.forename: Zachary M
authors.initials: ZM
authors.lastname: Mayko
authors.forename: Michael D
authors.initials: MD
authors.lastname: Straiko
authors.forename: Mark A
authors.initials: MA
authors.lastname: Terry
mesh_terms: D000368:Aged; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery*; D002386:Cataract / Q000503:physiopathology; D063171:Corneal Pachymetry; D019781:Corneal Topography; D057111:Descemet Stripping Endothelial Keratoplasty; D005260:Female; D005642:Fuchs' Endothelial Dystrophy / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology