title: Surface-Imprinted Magnetic Carboxylated Cellulose Nanocrystals for the Highly Selective Extraction of Six Fluoroquinolones from Egg Samples.
abstract: We herein describe a novel adsorbent based on molecularly imprinted polymers (MIPs) on the surface of magnetic carboxylated cellulose nanocrystals (Fe3O4@CCNs@MIPs) for the separation and purification of six fluoroquinolones (FQs) from egg samples. The obtained Fe3O4@CCNs@MIPs not only exhibited a large surface area and specific recognition toward FQs, but also were easily gathered and separated from the egg samples using an external magnetic field. The morphologies and surface groups of the Fe3O4@CCNs@MIPs were assessed by X-ray photoelectron spectroscopy, transmission electron microscopy, vibrating sample magnetometry, X-ray diffraction, thermogravimetric analysis, Fourier transform infrared spectroscopy, and Brunauer-Emmett-Teller surface area analysis. The Fe3O4@CCNs@MIPs exhibited high selectivity toward six structurally similar FQs. An enrichment approach was established for the measurement of six FQs from egg samples using Fe3O4@CCNs@MIPs coupled to high-performance liquid chromatography. The recovery of spiked FQs ranged from 75.2-104.9% and limit of detection was in the range of 3.6-18.4 ng g-1for the six FQs. Therefore, the proposed method is a promising technique for the enrichment, separation, and determination of FQs from biomatrices.
authors.affiliation: School of Food and Pharmacy, Zhejiang Ocean University , Zhoushan 316022, P.R. China.
authors.forename: Yan-Fei
authors.initials: YF
authors.lastname: Wang
authors.affiliation: School of Food and Pharmacy, Zhejiang Ocean University , Zhoushan 316022, P.R. China.
authors.forename: Yang-Guang
authors.initials: YG
authors.lastname: Wang
authors.affiliation: School of Food and Pharmacy, Zhejiang Ocean University , Zhoushan 316022, P.R. China.
authors.forename: Xiao-Kun
authors.identifier: http://orcid.org/0000-0002-8534-0279
authors.initials: XK
authors.lastname: Ouyang
authors.affiliation: School of Food and Pharmacy, Zhejiang Ocean University , Zhoushan 316022, P.R. China.
authors.forename: Li-Ye
authors.initials: LY
authors.lastname: Yang
mesh_terms: D000327:Adsorption; D002482:Cellulose; D024841:Fluoroquinolones; D054802:Molecular Imprinting; D053758:Nanoparticles; D011108:Polymers; D052616:Solid Phase Extraction
chemical_list: D024841:Fluoroquinolones; D011108:Polymers; D002482:Cellulose
keywords: biomatrices; carboxylated cellulose nanocrystals; fluoroquinolones; high-performance liquid chromatography; molecularly imprinted polymers