title: Early-Phase Recovery of Cardiorespiratory Measurements after Maximal Cardiopulmonary Exercise Testing in Patients with Chronic Obstructive Pulmonary Disease.
abstract: Background. This study investigated respiratory gas exchanges and heart rate (HR) kinetics during early-phase recovery after a maximal cardiopulmonary exercise test (CPET) in patients with chronic obstructive pulmonary disease (COPD) grouped according to airflow limitation.Methods. Thirty control individuals (control group: CG) and 81 COPD patients (45 with "mild" or "moderate" airflow limitation, COPDI-II, versus 36 with "severe" or "very severe" COPD, COPDIII-IV) performed a maximal CPET. The first 3 min of recovery kinetics was investigated for oxygen uptake ([Formula: see text]O2), minute ventilation ([Formula: see text]), respiratory equivalence, and HR. The time for [Formula: see text]O2to reach 25% (T1/4[Formula: see text]O2) of peak value was also determined and compared.Results. The [Formula: see text]O2, [Formula: see text], and HR recovery kinetics were significantly slower in both COPD groups than CG (p< 0.05). Moreover, COPDIII-IVgroup had significantly higher [Formula: see text]O2and [Formula: see text] during recovery than COPDI-IIgroup (p< 0.05). T1/4[Formula: see text]O2significantly differed between groups (p< 0.01; 58 ± 18 s in CG, 79 ± 26 s in COPDI-IIgroup, and 121 ± 34 s in COPDIII-IV) and was significantly correlated with forced expiratory volume in one second in COPD patients (p< 0.001,r= 0.53) and with peak power output (p< 0.001,r= 0.59).Conclusion. The COPD groups showed slower kinetics in the early recovery period than CG, and the kinetics varied with severity of airflow obstruction.
authors.affiliation: Service de Pneumologie, Hôpital de Bois-Guillaume, CHU de Rouen, 76031 Rouen Cedex, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Bellefleur
authors.affiliation: Service de Physiologie Digestive, Urinaire, Respiratoire et Sportive, CHU de Rouen, 76000 Rouen, France.
authors.forename: David
authors.initials: D
authors.lastname: Debeaumont
authors.affiliation: Service de Physiologie Digestive, Urinaire, Respiratoire et Sportive, CHU de Rouen, 76000 Rouen, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Boutry
authors.affiliation: Service de Physiologie Digestive, Urinaire, Respiratoire et Sportive, CHU de Rouen, 76000 Rouen, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Netchitailo
authors.affiliation: Service de Pneumologie, Hôpital de Bois-Guillaume, CHU de Rouen, 76031 Rouen Cedex, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Cuvelier
authors.affiliation: Service de Pneumologie, Hôpital de Bois-Guillaume, CHU de Rouen, 76031 Rouen Cedex, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Muir
authors.affiliation: Service de Physiologie Digestive, Urinaire, Respiratoire et Sportive, CHU de Rouen, 76000 Rouen, France; UPRES EA 3830, GRHV, 76000 Rouen, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Tardif
authors.affiliation: CETAPS, EA 3832, UFR STAPS, Université de Rouen, 76821 Mont Saint Aignan, France.
authors.forename: Jérémy
authors.identifier: 0000-0001-6515-7736
authors.initials: J
authors.lastname: Coquart
mesh_terms: D000368:Aged; D000072599:Cardiorespiratory Fitness / Q000502:physiology; D005080:Exercise Test / Q000379:methods*; D005260:Female; D005602:France / Q000453:epidemiology; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D020127:Recovery of Function / Q000502:physiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors