title: Dosimetric Improvements in Balloon Based Brachytherapy Using the Contura®Multi-Lumen Balloon (MLB) Catheter to Deliver Accelerated Partial Breast Irradiation.
abstract: OBJECTIVE
  Preliminary dosimetric findings in patients managed with the Contura®Multi-Lumen Balloon (MLB) breast brachytherapy catheter to deliver accelerated partial breast irradiation (APBI) on a multi-institutional phase IV registry trial were reviewed.
  
  
  METHODS
  CT-based 3D planning with dose optimization was performed for all patients. For the study, new ideal dosimetric goals were developed: 1) ≥ 95% of the prescribed dose (PD) covering ≥ 90% of the target volume (TV), 2) a maximum skin dose ≤ 125% of the PD, 3) maximum rib dose ≤ 145% of the PD, and 4) the V150 ≤ 50 cc and V200 ≤ 10 cc. The frequency of concurrently achieving these dosimetric goals using the Contura®MLB was investigated.
  
  
  RESULTS
  194 cases were evaluable. Employing the MLB, all ideal dosimetric criteria were achieved in 76% of cases. Evaluating dosimetric criteria separately, 90% and 89% of cases met the new ideal skin and rib dose criteria, respectively. In 96%, ideal TV coverage goals were achieved and in 96%, dose homogeneity criteria (V150 and V200) were met. For skin spacing ≥ 5-7 mm, the median skin dose was 121% of the PD and when < 5 mm, the median skin dose was 124.4%. For rib distancees < 5 mm, the median rib dose was reduced to 136.4% of the PD. For skin spacing < 7 mm and distance to rib < 5 mm, the median skin and rib doses were concurrently limited to 121% and 142.8% of the PD, respectively.
  
  
  CONCLUSIONS
  The Contura®MLB catheter provides potential improvements in dosimetric capabilities (i.e., reduced skin and rib doses and improved TV coverage) in many clinical scenarios.
authors.affiliation: William Beaumont Hospital, Royal Oak, MI.
authors.forename: Frank A
authors.initials: FA
authors.lastname: Vicini
authors.affiliation: Virginia Commonwealth University, Richmond, VA.
authors.forename: Arthur
authors.initials: A
authors.lastname: Douglas
authors.affiliation: Virginia Commonwealth University, Richmond, VA.
authors.forename: Dorin
authors.initials: D
authors.lastname: Todor
authors.affiliation: Allegheny General Hospital, Pittsburgh, PA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Julian
authors.affiliation: BioStat International, Tampa, Fl, USA.
authors.forename: Maureen
authors.initials: M
authors.lastname: Lyden
keywords: Contura®; balloon brachytherapy; breast conserving therapy