title: A prospective study of the association between total sleep duration and incident hypertension.
abstract: The aim of this prospective study was to evaluate total sleep duration as a potential risk factor for the development of hypertension after a mean of 2.6 years of follow-up. The study participants comprised 1715 Korean adults aged 40 to 70 years. The participants were without hypertension at baseline (2005-2008) and during follow-up (2008-2011) to determine the incident cases of hypertension. Based on a self-reported questionnaire, the individuals were stratified according to total sleep duration (<6 hours, 6-7.9 hours, 8-9.9 hours, ≥10 hours). Hypertension was defined according to the Eighth Joint National Committee (JNC 8) guidelines. After an average of 2.6 years of follow-up, 164 (9.56%) participants developed hypertension. In multivariate adjusted models, the odds ratio for new-onset hypertension was 1.71 (95% confidence interval, 1.01-2.89) in participants with a short sleep duration (<6 hours) compared with those who reported 6 to 7.9 hours of sleep. Long sleep duration (more than 8 hours) did not have any significant difference on incident hypertension. Among middle-aged and elderly Korean adults, short sleepers were independently associated with a higher risk of developing hypertension.
authors.affiliation: Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
authors.forename: Dhananjay
authors.initials: D
authors.lastname: Yadav
authors.affiliation: Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
authors.forename: Dae Sung
authors.initials: DS
authors.lastname: Hyun
authors.affiliation: Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
authors.forename: Song Vogue
authors.initials: SV
authors.lastname: Ahn
authors.affiliation: Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea.
authors.forename: Sang-Baek
authors.initials: SB
authors.lastname: Koh
authors.affiliation: Department of Cardiology, Yonsei University Wonju College of Medicine, Wonju, South Korea.
authors.forename: Jang Young
authors.initials: JY
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D001795:Blood Pressure Determination / Q000295:instrumentation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D057566:Self Report; D012890:Sleep / Q000502:physiology*; D012893:Sleep Wake Disorders / Q000150:complications* / Q000453:epidemiology; D013997:Time Factors
keywords: Korean adults; hypertension; prospective study; sleep duration