title: A Quick Reference on Chloride.
abstract: Chloride is an essential element, playing important roles in digestion, muscular activity, regulation of body fluids, and acid-base balance. As the most abundant anion in extracellular fluid, chloride plays a major role in maintaining electroneutrality. Chloride is intrinsically linked to sodium in maintaining osmolality and fluid balance and has an inverse relationship with bicarbonate in maintaining acid-base balance. It is likely because of these close ties that chloride does not get the individual attention it deserves; we can use these facts to simplify and interpret changes in serum chloride concentrations.
authors.affiliation: Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523, USA. Electronic address: Andrea.Bohn@ColoState.EDU.
authors.forename: Andrea A
authors.initials: AA
authors.lastname: Bohn
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, 700 Southwest 30th Street, Magruder Hall, Corvallis, OR 97331, USA.
authors.forename: Helio Autran
authors.initials: HA
authors.lastname: de Morais
mesh_terms: D000137:Acid-Base Imbalance / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D002712:Chlorides / Q000378:metabolism* / Q000494:pharmacology; D012016:Reference Values; D017693:Sodium Bicarbonate / Q000494:pharmacology
chemical_list: D002712:Chlorides; D017693:Sodium Bicarbonate
keywords: Analysis; Chloride; Reference; Sodium bicarbonate