title: [The role of intestinal microbiota in the response to anti-tumor therapies].
abstract: The gut microbiota is involved in a lot of crucial physiological functions and maintains a symbiotic relationship with the host. Lately, in light of new evidences, an unexpected role of commensals has been depicted. Several studies addressing the role of gut microbiota in the immunomodulatory properties of anti-cancer regimens, such as immunotherapy and chemotherapy, reveal that commensals are required to mount complete and efficient antitumor immune responses. Therefore, exploration of microbiota-derived compounds in the future could represent a therapeutic option in the armamentarium of cancer treatments.
authors.affiliation: Gustave Roussy cancer campus, 114, rue Édouard Vaillant, 94800 Villejuif, France - Université Paris-Saclay, Le Kremlin-Bicêtre, France - Unité Inserm U1015, 94800 Villejuif, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Vétizou
authors.affiliation: Gustave Roussy cancer campus, 114, rue Édouard Vaillant, 94800 Villejuif, France - Université Paris-Saclay, Le Kremlin-Bicêtre, France - Unité Inserm U1015, 94800 Villejuif, France.
authors.forename: Romain
authors.initials: R
authors.lastname: Daillère
authors.affiliation: Gustave Roussy cancer campus, 114, rue Édouard Vaillant, 94800 Villejuif, France - Université Paris-Saclay, Le Kremlin-Bicêtre, France - Unité Inserm U1015, 94800 Villejuif, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Zitvogel
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001691:Biological Therapy / Q000639:trends; D019008:Drug Resistance, Neoplasm; D064806:Dysbiosis / Q000209:etiology; D000069196:Gastrointestinal Microbiome / Q000187:drug effects / Q000276:immunology; D006801:Humans; D007167:Immunotherapy / Q000009:adverse effects / Q000379:methods; D009369:Neoplasms / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents