title: The HUGE formula (hematocrit, urea, gender) for screening for chronic kidney disease in elderly patients: a study of diagnostic accuracy.
abstract: Chronically reduced glomerular filtration rate (GFR) in old people does not always mean that they suffer from chronic kidney disease (CKD) since their GFR can just be reduced by aging. The HUGE equation has been recently described and validated in Spain for screening CKD without taking into account the patient's GFR value. This equation is based on patient's hematocrit, plasma urea levels and gender. The present study documented that the HUGE equation had and acceptable performance for screening CKD in elderly Argentine patients.
authors.affiliation: Ageing Biology Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. carlos.musso@hospitalitaliano.org.ar.|Nephrology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. carlos.musso@hospitalitaliano.org.ar.
authors.forename: Carlos G
authors.initials: CG
authors.lastname: Musso
authors.affiliation: Medical Informatic Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Eduardo
authors.initials: E
authors.lastname: de Los Rios
authors.affiliation: Nephrology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Manuel
authors.initials: M
authors.lastname: Vilas
authors.affiliation: Division of Family and Community Medicine and Research Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.|Department of Public Health, Instituto Universitario Hospital Italiano, Buenos Aires, Argentina.
authors.forename: Sergio
authors.initials: S
authors.lastname: Terrasa
authors.affiliation: Nephrology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Griselda
authors.initials: G
authors.lastname: Bratti
authors.affiliation: Nephrology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Federico
authors.initials: F
authors.lastname: Varela
authors.affiliation: Nephrology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Rosa Diez
authors.affiliation: Ageing Biology Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Jose
authors.initials: J
authors.lastname: Jauregui
authors.affiliation: Medical Informatic Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Daniel
authors.initials: D
authors.lastname: Luna
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001118:Argentina; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005919:Glomerular Filtration Rate; D006400:Hematocrit; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D055641:Mathematical Concepts; D051436:Renal Insufficiency, Chronic / Q000097:blood* / Q000175:diagnosis* / Q000503:physiopathology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012737:Sex Factors; D014508:Urea / Q000097:blood*
chemical_list: D014508:Urea
keywords: Chronic kidney disease; Elderly; HUGE equation