title: Comment on "A small-molecule antivirulence agent for treating Clostridium difficile infection".
abstract: New insights into the mechanism of action of ebselen, a small-molecule antivirulence agent that reduces disease pathology in a mouse model of Clostridium difficile infection, suggest a different molecular target may be responsible for its efficacy.
authors.affiliation: Molecular Structure & Function, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.
authors.forename: Greg L
authors.initials: GL
authors.lastname: Beilhartz
authors.affiliation: Molecular Structure & Function, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.
authors.forename: John
authors.initials: J
authors.lastname: Tam
authors.affiliation: Molecular Structure & Function, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.|Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
authors.forename: Zhifen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Molecular Structure & Function, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada. roman.melnyk@sickkids.ca.|Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
authors.forename: Roman A
authors.initials: RA
authors.lastname: Melnyk
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D016360:Clostridioides difficile; D003015:Clostridium Infections; D051379:Mice
chemical_list: D000900:Anti-Bacterial Agents