title: NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017.
abstract: The NCCN Clinical Practice Guidelines in Oncology for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling for hereditary cancer syndromes and risk management recommendations for patients who are diagnosed with a syndrome. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer. The NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meets at least annually to review comments from reviewers within their institutions, examine relevant new data from publications and abstracts, and reevaluate and update their recommendations. The NCCN Guidelines Insights summarize the panel's discussion and most recent recommendations regarding risk management for carriers of moderately penetrant genetic mutations associated with breast and/or ovarian cancer.
authors.affiliation: Fox Chase Cancer Center
authors.forename: Mary B
authors.initials: MB
authors.lastname: Daly
authors.affiliation: The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute
authors.forename: Robert
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authors.lastname: Pilarski
authors.affiliation: St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center
authors.forename: Michael
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authors.lastname: Berry
authors.affiliation: Huntsman Cancer Institute at the University of Utah
authors.forename: Saundra S
authors.initials: SS
authors.lastname: Buys
authors.affiliation: University of Alabama at Birmingham Comprehensive Cancer Center
authors.forename: Meagan
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authors.affiliation: FORCE: Facing Our Risk of Cancer Empowered
authors.forename: Susan
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authors.affiliation: Dana-Farber/Brigham and Women’s Cancer Center
authors.forename: Judy E
authors.initials: JE
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authors.affiliation: Duke Cancer Institute
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authors.initials: ND
authors.lastname: Kauff
authors.affiliation: Robert H. Lurie Comprehensive Cancer Center of Northwestern University
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authors.affiliation: University of Colorado Cancer Center
authors.forename: Catherine
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authors.affiliation: Huntsman Cancer Institute at the University of Utah
authors.forename: Wendy
authors.initials: W
authors.lastname: Kohlmann
authors.affiliation: Stanford Cancer Institute
authors.forename: Allison
authors.initials: A
authors.lastname: Kurian
authors.affiliation: The University of Texas MD Anderson Cancer Center
authors.forename: Jennifer K
authors.initials: JK
authors.lastname: Litton
authors.affiliation: UC San Diego Moores Cancer Center
authors.forename: Lisa
authors.initials: L
authors.lastname: Madlensky
authors.affiliation: University of Michigan Comprehensive Cancer Center
authors.forename: Sofia D
authors.initials: SD
authors.lastname: Merajver
authors.affiliation: Memorial Sloan Kettering Cancer Center
authors.forename: Kenneth
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authors.lastname: Offit
authors.affiliation: Moffitt Cancer Center
authors.forename: Tuya
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authors.lastname: Pal
authors.affiliation: Fred & Pamela Buffett Cancer Center
authors.forename: Gwen
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authors.lastname: Reiser
authors.affiliation: Massachusetts General Hospital Cancer Center
authors.forename: Kristen Mahoney
authors.initials: KM
authors.lastname: Shannon
authors.affiliation: University of Washington Medical Center/Seattle Cancer Care Alliance
authors.forename: Elizabeth
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authors.lastname: Swisher
authors.affiliation: Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute
authors.forename: Shaveta
authors.initials: S
authors.lastname: Vinayak
authors.affiliation: Roswell Park Cancer Institute
authors.forename: Nicoleta C
authors.initials: NC
authors.lastname: Voian
authors.affiliation: City of Hope Comprehensive Cancer Center
authors.forename: Jeffrey N
authors.initials: JN
authors.lastname: Weitzel
authors.affiliation: Mayo Clinic Cancer Center
authors.forename: Myra J
authors.initials: MJ
authors.lastname: Wick
authors.affiliation: Vanderbilt-Ingram Cancer Center
authors.forename: Georgia L
authors.initials: GL
authors.lastname: Wiesner
authors.affiliation: National Comprehensive Cancer Network
authors.forename: Mary
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authors.lastname: Dwyer
authors.affiliation: National Comprehensive Cancer Network
authors.forename: Susan
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authors.lastname: Darlow
mesh_terms: D005260:Female; D005817:Genetic Counseling / Q000592:standards*; D005820:Genetic Testing / Q000592:standards*; D061325:Hereditary Breast and Ovarian Cancer Syndrome / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D009154:Mutation; D017410:Practice Guidelines as Topic; D018570:Risk Assessment / Q000592:standards; D012307:Risk Factors