title: Glycan Microarray Reveal the Sweet Side of Cancer Vaccines.
abstract: Advances in genomics and bioinformatics facilitated identification of tumor-specific neoantigens as optimal targets for cancer immunotherapy. In this hot topic, most efforts focus on mutant peptide antigens, overlooking tumor-associated glycosylation changes. Given the latest progress in glycomics, in this issue of Cell Chemical Biology, Xia et al. (2016) use glyco-antigen microarrays to investigate immune responses to whole cancer vaccines and provide important insights into vaccine efficacy.
authors.affiliation: Department of Cell Research and Immunology, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: vkaravani@post.tau.ac.il.
authors.forename: Vered
authors.initials: V
authors.lastname: Padler-Karavani