title: Early dural metastasis from a case of glioblastoma with primitive neuroectodermal differentiation: A case report and literature review.
abstract: Glioblastoma with a primitive neuroectodermal (PNET) variant is a rare primary parenchymal tumor. Only a few cases of extraparenchymal metastasis are reported in world literature. Although the overall survival duration of glioblastoma multiforme (GBM) with primitive neuroectodermal tumor (PNET) variety may be prolonged in comparison to classical glioblastoma, the metastatic trend is completely different, and the prognosis is worse. We report an early dural metastasis of pure PNET component appearing in a case of primary glioblastoma with PNET variant. The lesson learned from this case is to look for early craniospinal metastasis in GBM patient with PNET component, even after completion of adjuvant radiochemotherapy.
authors.affiliation: Department of Neurosurgery, LSU Health-Shreveport, 1501 Kings Highway, Shreveport, LA 71103-33932, USA.
authors.forename: Subhas K
authors.initials: SK
authors.lastname: Konar
authors.affiliation: Department of Neurosurgery, LSU Health-Shreveport, 1501 Kings Highway, Shreveport, LA 71103-33932, USA.
authors.forename: Shyamal C
authors.initials: SC
authors.lastname: Bir
authors.affiliation: Department of Neurosurgery, LSU Health-Shreveport, 1501 Kings Highway, Shreveport, LA 71103-33932, USA.
authors.forename: Tanmoy K
authors.initials: TK
authors.lastname: Maiti
authors.affiliation: Department of Neurosurgery, LSU Health-Shreveport, 1501 Kings Highway, Shreveport, LA 71103-33932, USA.
authors.forename: Devi Prasad
authors.initials: DP
authors.lastname: Patra
authors.affiliation: Department of Pathology, LSU Health-Shreveport, 1501 Kings Highway, Shreveport, LA 71103-33932, USA.
authors.forename: Angela C
authors.initials: AC
authors.lastname: DiPoto Brahmbhatt
authors.affiliation: Department of Pathology, LSU Health-Shreveport, 1501 Kings Highway, Shreveport, LA 71103-33932, USA.
authors.forename: Jamie A
authors.initials: JA
authors.lastname: Jacobsohn
authors.affiliation: Department of Neurosurgery, LSU Health-Shreveport, 1501 Kings Highway, Shreveport, LA 71103-33932, USA. Electronic address: ananda@lsuhsc.edu.
authors.forename: Anil
authors.initials: A
authors.lastname: Nanda
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D004388:Dura Mater / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005909:Glioblastoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009362:Neoplasm Metastasis; D018242:Neuroectodermal Tumors, Primitive / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
keywords: Differentiation; Glioblastoma; Metastasis; Primary neuroectodermal tumor