title: Anaplastic large cell lymphoma masquerading as osteomyelitis of the shoulder: an uncommon presentation.
abstract: The presentation of anaplastic lymphoma kinase protein (ALK)-negative anaplastic large cell lymphoma (ALCL) in bone is rare. We describe a patient with ALK-negative ALCL presenting with clinical and radiographic findings suggesting osteomyelitis 6 months after left rotator cuff repair surgery. A review of the characteristics of ALK-negative ALCL with primary bone involvement is presented. ALCL should be considered in patients not responding to therapies for osteomyelitis.
authors.affiliation: Department of Medicine, George Washington University, Washington, DC, USA.|Department of Medical Services (111), Veterans Affairs Medical Center, Washington, DC, USA.
authors.forename: Matthew
authors.identifier: http://orcid.org/0000-0002-5991-0709
authors.initials: M
authors.lastname: Tuck
authors.affiliation: Department of Internal Medicine, Cedars-Sinai Health System, Los Angeles, California, USA.
authors.forename: Jane
authors.initials: J
authors.lastname: Lim
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
authors.forename: Jose
authors.initials: J
authors.lastname: Lucar
authors.affiliation: Department of Medical Services (111), Veterans Affairs Medical Center, Washington, DC, USA.
authors.forename: Debra
authors.initials: D
authors.lastname: Benator
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000627:therapeutic use; D005047:Etoposide / Q000627:therapeutic use; D006801:Humans; D008207:Lymphatic Metastasis; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D010019:Osteomyelitis / Q000175:diagnosis*; D000072078:Positron Emission Tomography Computed Tomography; D011241:Prednisone / Q000627:therapeutic use; D012782:Shoulder; D012878:Skin Neoplasms / Q000556:secondary; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone