title: The Role of Robot-Assisted Radical Prostatectomy in High-Risk Prostate Cancer.
abstract: Prostate cancer (PCa) is stratified into different risk categories based on the patient's prognosis. High-risk disease was formerly characterized by an increased risk of metastasis and lethality, requiring complex treatments. Surgery was recently highlighted to have a pivotal role for the treatment of such cases, even as monotherapy. In the past, open radical prostatectomy was performed for most patients with high-risk PCa; however, robot-assisted radical prostatectomy (RARP) emerged as a reasonable option because it provided optimal outcomes for low- and intermediate-risk PCa. Robust studies are lacking to properly assess the role of RARP for high-risk PCa. We summarize this knowledge and present a literature review on the perioperative recovery and functional and oncologic outcomes of RARP for the treatment of patients with high-risk PCa.
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .|2 Division of Urology, University of Sao Paulo , Sao Paulo, Brazil .
authors.forename: Victor
authors.initials: V
authors.lastname: Srougi
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .|3 Division of Urology, ABC Medical School , Sao Paulo, Brazil .
authors.forename: Rafael R
authors.initials: RR
authors.lastname: Tourinho-Barbosa
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Igor
authors.initials: I
authors.lastname: Nunes-Silva
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Mohammed
authors.initials: M
authors.lastname: Baghdadi
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Silvia
authors.initials: S
authors.lastname: Garcia-Barreras
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Gregory
authors.initials: G
authors.lastname: Rembeyo
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Sophie S
authors.initials: SS
authors.lastname: Eiffel
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Eric
authors.initials: E
authors.lastname: Barret
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Francois
authors.initials: F
authors.lastname: Rozet
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Marc
authors.initials: M
authors.lastname: Galiano
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Rafael
authors.initials: R
authors.lastname: Sanchez-Salas
authors.affiliation: 1 Department of Urology, Institut Montsouris , Paris, France .
authors.forename: Xavier
authors.initials: X
authors.lastname: Cathelineau
mesh_terms: D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008297:Male; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology / Q000601:surgery*; D065287:Robotic Surgical Procedures / Q000379:methods; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: high risk; locally advanced; prostate cancer; prostatectomy; robot-assisted radical prostatectomy; robotic