title: Datasets for next-generation sequencing of DNA and RNA from urine and plasma of patients with prostate cancer.
abstract: Current prostate cancer (PCa) diagnostic tests suffer from insufficient sensitivity and specificity. Novel biomarkers that can be detected by minimally invasive methods are of a particular value. Here we provide two datasets. The first one is on the whole transcriptome profiling by RNA-seq of urine and plasma obtained from patients with PCa and benign prostatic hyperplasia (BPH). The second one represents targeted sequencing of DNA from urine and plasma of patients with PCa and BPH. Both datasets are available at NCBI Sequence Read Archive under Accession No. SRP093707 and No. SRP093842 respectively.
authors.affiliation: Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia; Moscow Institute of Physics and Technology, Dolgoprudnyi, Russia.
authors.forename: A S
authors.initials: AS
authors.lastname: Nikitina
authors.affiliation: Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia.
authors.forename: E I
authors.initials: EI
authors.lastname: Sharova
authors.affiliation: Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Danilenko
authors.affiliation: Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Selezneva
authors.affiliation: Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia.
authors.forename: T B
authors.initials: TB
authors.lastname: Butusova
authors.affiliation: Department of Urology, Moscow State Medical Stomatological University, Moscow, Russia.
authors.forename: A O
authors.initials: AO
authors.lastname: Vasiliev
authors.affiliation: Department of Urology, Moscow State Medical Stomatological University, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Govorov
authors.affiliation: Department of Urology, Moscow State Medical Stomatological University, Moscow, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Prilepskaya
authors.affiliation: Department of Urology, Moscow State Medical Stomatological University, Moscow, Russia.
authors.forename: D Y
authors.initials: DY
authors.lastname: Pushkar
authors.affiliation: Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia; Moscow Institute of Physics and Technology, Dolgoprudnyi, Russia.
authors.forename: E S
authors.initials: ES
authors.lastname: Kostryukova
keywords: Benign prostatic hyperplasia; Prostate cancer; RNA-seq; Targeted DNA sequencing; Transcriptome