title: Oxidative Aza-Annulation of Enynyl Azides to 2-Keto/Formyl-1H-pyrroles.
abstract: A method for the construction of pyrroles bearing a 2-keto or formyl group through the intramolecular oxidative aza-annulation of enynyl azides is reported for the first time. It involves a sequential carbon-nitrogen/carbon-oxygen bond formations, and the combination of AuCl3with AgSbF6was identified as a suitable reagent system to promote the present reaction. The required enynyl azides are readily prepared from Morita-Baylis-Hillman (MBH) acetates of acetylenic aldehydes.
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.|Academy of Scientific and Innovative Research, New Delhi, India.
authors.forename: Chada Raji
authors.identifier: 0000-0003-1491-7381
authors.initials: CR
authors.lastname: Reddy
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.|Academy of Scientific and Innovative Research, New Delhi, India.
authors.forename: Sujatarani A
authors.initials: SA
authors.lastname: Panda
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500607, India.
authors.forename: Andhavaram
authors.initials: A
authors.lastname: Ramaraju