title: Taste function assessed by electrogustometry in burning mouth syndrome: a case-control study.
abstract: OBJECTIVE
  Idiopathic burning mouth syndrome (iBMS) is characterized by oral persistent pain without any clinical or biological abnormality. The aim of this study was to evaluate taste function in iBMS subjects and healthy controls.
  
  
  METHODS
  Electrogustometric thresholds (EGMt) were recorded in 21 iBMS patients and 21 paired-matched controls at nine loci of the tongue assessing fungiform and foliate gustatory papillae function. Comparison of EGMt was performed using the nonparametric Wilcoxon signed-rank test. A correlation between EGMt and self-perceived pain intensity assessed using a visual analogic scale (VAS) was analyzed with the Spearman coefficient. The level of significance was fixed at P < 0.05.
  
  
  RESULTS
  Mean EGMt were significantly increased with iBMS for right side of the dorsum of the tongue and right lateral side of the tongue (P < 0.05). In the iBMS group, VAS scores were significantly correlated to EGMt at the tip of the tongue (r = -0.59; P < 0.05) and at the right and left lateral sides of the tongue (respectively, r = -0.49 and r = -0.47; P < 0.05).
  
  
  CONCLUSIONS
  These data depicted impaired taste sensitivity in iBMS patients within fungiform and foliate taste bud fields and support potent gustatory/nociceptive interaction in iBMS.
authors.affiliation: UFR Odontologie, Université Paris Diderot, Paris, France.
authors.forename: A
authors.identifier: http://orcid.org/0000-0003-3830-5259
authors.initials: A
authors.lastname: Braud
authors.affiliation: UFR Odontologie, Université Paris Diderot, Paris, France.|Groupe Hospitalier Pitie-Salpêtrière-Charles-Foix, Paris, France.
authors.forename: V
authors.initials: V
authors.lastname: Descroix
authors.affiliation: Institut Pasteur, ICAReB platform of the Center for Translational Science, Paris, France.
authors.forename: M-N
authors.initials: MN
authors.lastname: Ungeheuer
authors.affiliation: Institut Pasteur, ICAReB platform of the Center for Translational Science, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Rougeot
authors.affiliation: UFR Odontologie, Université Paris Diderot, Paris, France.|Groupe Hospitalier Pitie-Salpêtrière-Charles-Foix, Paris, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Boucher
mesh_terms: D000368:Aged; D002054:Burning Mouth Syndrome / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D013649:Taste / Q000502:physiology*; D013650:Taste Buds / Q000503:physiopathology*; D013652:Taste Threshold
keywords: burning mouth syndrome; electrogustometry; idiopathic; pain; taste