title: Primary and secondary metabolites of an European edible mushroom and its nutraceutical value: Suillus bellinii (Inzenga) Kuntze.
abstract: In this work, we report the study on the composition in primary and secondary metabolites of the polar and less-polar fractions obtained from the fruiting bodies of Suillus bellinii (Inzenga) Kuntze collected from Central Italy. Thirteen compounds were identified through a series of classical chromatographic methods and through spectroscopic techniques (nuclear magnetic resonance (NMR) and mass spectrometry (MS)), namely suillin (1), ergosterol (2), glutamic acid (3), isoleucine (4), leucine (5), threonine (6), tyrosine (7), valine (8), D-mannitol (9), sucrose (10), D-sorbitol (11), fumaric acid (12) and alanine (13). These results allowed us to make specific considerations about the possible applications of this mushroom, which vary from medicine, due to the high cytotoxic and antitumor properties of suillin (1), to nutritional values, due to the presence of essential nutrients as amino acids and pre-vitamin D2(ergosterol), together with low-calories sweeteners, confirming the close association between the identified components and the health-promoting properties of this species.
authors.affiliation: a Dipartimento di Chimica , Università di Roma "La Sapienza" , Roma , Italy.
authors.forename: Alessandro
authors.identifier: http://orcid.org/0000-0003-1492-6739
authors.initials: A
authors.lastname: Venditti
authors.affiliation: b Dipartimento di Biologia Ambientale , Università di Roma "La Sapienza" , Roma , Italy.
authors.forename: Claudio
authors.identifier: http://orcid.org/0000-0002-2968-5264
authors.initials: C
authors.lastname: Frezza
authors.affiliation: a Dipartimento di Chimica , Università di Roma "La Sapienza" , Roma , Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Sciubba
authors.affiliation: b Dipartimento di Biologia Ambientale , Università di Roma "La Sapienza" , Roma , Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Serafini
authors.affiliation: a Dipartimento di Chimica , Università di Roma "La Sapienza" , Roma , Italy.
authors.forename: Armandodoriano
authors.identifier: http://orcid.org/0000-0001-8622-5742
authors.initials: A
authors.lastname: Bianco
mesh_terms: D000363:Agaricales / Q000737:chemistry* / Q000378:metabolism*; D000596:Amino Acids / Q000032:analysis / Q000378:metabolism*; D019587:Dietary Supplements / Q000032:analysis; D004224:Diterpenes / Q000302:isolation & purification; D004875:Ergosterol / Q000302:isolation & purification / Q000378:metabolism; D007558:Italy; D009682:Magnetic Resonance Spectroscopy; D009753:Nutritive Value; D010636:Phenols / Q000302:isolation & purification
chemical_list: D000596:Amino Acids; D004224:Diterpenes; D010636:Phenols; C061636:suillin; D004875:Ergosterol
keywords: Suillus bellinii (Inzenga) Kuntze; essential amino acids; meroterpene; pre-vitamin D2; primary metabolites; secondary metabolites