title: Crossing the Boundaries of Our Current Healthcare System by Integrating Ultra-Weak Photon Emissions with Metabolomics.
abstract: The current healthcare system is hampered by a reductionist approach in which diagnostics and interventions focus on a specific target, resulting in medicines that center on generic, static phenomena while excluding inherent dynamic nature of biological processes, let alone psychosocial parameters. In this essay, we present some limitations of the current healthcare system and introduce the novel and potential approach of combining ultra-weak photon emission (UPE) with metabolomics technology in order to provide a dynamic readout of higher organizational systems. We argue that the combination of metabolomics and UPE can bring a new, broader, view of health state and can potentially help to shift healthcare toward more personalized approach that improves patient well-being.
authors.affiliation: Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden UniversityLeiden, Netherlands; Sino-Dutch Center for Preventive and Personalized Medicine/Center for Photonics of Living Systems, Leiden UniversityLeiden, Netherlands.
authors.forename: Rosilene C Rossetto
authors.initials: RC
authors.lastname: Burgos
authors.affiliation: Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden UniversityLeiden, Netherlands; Sino-Dutch Center for Preventive and Personalized Medicine/Center for Photonics of Living Systems, Leiden UniversityLeiden, Netherlands; Meluna Research in BiophotonicsGeldermalsen, Netherlands.
authors.forename: Eduard P A
authors.initials: EP
authors.lastname: van Wijk
authors.affiliation: Sino-Dutch Center for Preventive and Personalized Medicine/Center for Photonics of Living Systems, Leiden UniversityLeiden, Netherlands; Meluna Research in BiophotonicsGeldermalsen, Netherlands.
authors.forename: Roeland
authors.initials: R
authors.lastname: van Wijk
authors.affiliation: Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden UniversityLeiden, Netherlands; Sino-Dutch Center for Preventive and Personalized Medicine/Center for Photonics of Living Systems, Leiden UniversityLeiden, Netherlands.
authors.forename: Min
authors.initials: M
authors.lastname: He
authors.affiliation: Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden UniversityLeiden, Netherlands; Sino-Dutch Center for Preventive and Personalized Medicine/Center for Photonics of Living Systems, Leiden UniversityLeiden, Netherlands.
authors.forename: Jan
authors.initials: J
authors.lastname: van der Greef
keywords: diagnostics; healthcare; metabolomics; system biology; ultra-weak photon emission