title: [The effect of occupational exposure to coal tar pitch workers' health].
abstract: Objective:To investigate the effect of occupational exposure to coal tar pitch on workers' health and metabolism.Methods:805 workers exposed to coal tar pitch were selected as exposure group from the produce and em-ploy factory. Other people handle administrative and logistical affairs who not exposed to coal tar pitch were selected as control group. Fix-point sample of air were collected to detect the concentration of coal tar pitch. Do physical examination and questionnaire to collect workers' basic and healthy information. To detect the metabolic product of urine samples in laboratory.Results:Anomaly detection rate of the skin in exposure group is 10.61. The lung function indices (FEV1.0%) in exposure group were significantly lower than control group (P<0.05) . The monocyte count and monocyte rate in expo-sure group were significantly higher than control group (P<0.05) . The metabolic product content of PAHS in urine sam-ples is significantly higher in exposed group than control group (P<0.05) .Conclusion:The metabolic product content of polycyclic aromatic hydrocarbon is higher in exposed workers. Coal tar pitch damage workers' skin and lung function. It can cause pruritus chromatodermatosis and so on.
authors.affiliation: School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Shandong Institute of Prevention and Control of Occupational Disease, Jinan250062, China.
authors.forename: X C
authors.initials: XC
authors.lastname: Sun
authors.forename: F
authors.initials: F
authors.lastname: Zhang
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.forename: C D
authors.initials: CD
authors.lastname: Lu
authors.forename: Z H
authors.initials: ZH
authors.lastname: Zhang
authors.forename: B
authors.initials: B
authors.lastname: Feng
authors.forename: H Y
authors.initials: HY
authors.lastname: Wei
authors.forename: X
authors.initials: X
authors.lastname: Meng
authors.forename: X L
authors.initials: XL
authors.lastname: Chen
authors.forename: H
authors.initials: H
authors.lastname: Shao
authors.forename: Z X
authors.initials: ZX
authors.lastname: Wang
mesh_terms: D003033:Coal Tar / Q000633:toxicity*; D006801:Humans; D008168:Lung / Q000503:physiopathology; D016273:Occupational Exposure; D011084:Polycyclic Aromatic Hydrocarbons; D012867:Skin / Q000473:pathology
chemical_list: D011084:Polycyclic Aromatic Hydrocarbons; D003033:Coal Tar