title: Factors influencing the quality of life perception in patients with type 2 diabetes mellitus.
abstract: OBJECTIVE
  To evaluate the impact of several factors on the patient's perception on quality of life in a group of patients with type 2 diabetes mellitus (T2DM).
  
  
  METHODS
  In this cross-sectional study, 198 patients with T2DM were enrolled according to a consecutive-case population-based study design. In all participants, the perception on the quality of life was measured using the quality of life index - diabetes version III proposed by Ferrans and Powers. We evaluated the impact of several anthropometric and diabetes-related (ie, diabetes history and quality of glycemic control) factors on the patient's perception on the quality of life.
  
  
  RESULTS
  The presence of diabetes complications was associated with a decreased quality of life: retinopathy (1 vs 5 points;P<0.001), chronic kidney disease (-1 vs 5 points;P<0.001), and neuropathy (-1 vs 5 points;P<0.001). A significant reverse correlation was found between the patient's quality of life and depression's severity (Spearman'sr=-0.345;P<0.001) and body mass index (Spearman'sr=-0.158;P=0.026). A positive association between the quality of life and the quality of diabetes-related self-care activities was found (Spearman'sr=0.338;P<0.001). No significant association was found between the patient's quality of life and the quality of glycemic control, diabetes duration, age, gender, or smoking status.
  
  
  CONCLUSIONS
  To improve the patient's quality of life, special care should be given to the modifiable diabetes-related factors: the prevention and treatment of diabetes complications, treatment of depression, and weight loss in obese and overweight patients.
authors.affiliation: Second Department of Internal Medicine.
authors.forename: Romulus
authors.initials: R
authors.lastname: Timar
authors.affiliation: Department of Pediatrics.
authors.forename: Iulian
authors.initials: I
authors.lastname: Velea
authors.affiliation: Department of Functional Sciences.
authors.forename: Bogdan
authors.initials: B
authors.lastname: Timar
authors.affiliation: Department of Functional Sciences.
authors.forename: Diana
authors.initials: D
authors.lastname: Lungeanu
authors.affiliation: Department of Infectious Diseases.
authors.forename: Cristian
authors.initials: C
authors.lastname: Oancea
authors.affiliation: Faculty of General Medicine, "Victor Babes" University of Medicine and Pharmacy.
authors.forename: Deiana
authors.initials: D
authors.lastname: Roman
authors.affiliation: First Department of Surgery, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Octavian
authors.initials: O
authors.lastname: Mazilu
keywords: diabetes complications; diabetes-related self-care activities; quality of life; type 2 diabetes