title: Pneumococcal biliary tract infections - How rare are they?
abstract: Pneumococcal biliary tract infections (PBTIs) were reported as rare due to the bacterium's bile solubility. The purpose of this study was to determine the occurrence and clinical characteristics of PBTIs. A retrospective case series review was conducted from January 2006 to August 2014 at a tertiary referral university hospital in Japan. Patients with a blood or bile culture positive for Streptococcus pneumoniae diagnosed with definite cholangitis or cholecystitis according to Tokyo Guideline 2013 were enrolled in this study. Data on clinical information, treatments, and outcomes were collected. During 104 months, 48 cases of positive blood cultures and 13 cases of positive bile cultures were recorded, and after excluding 43 and 5 of these, respectively, a total of 10 patients were diagnosed with PBTI. Most patients (9/10) had biliary tract problems and biliary devices in place. PBTIs were not rare; conversely, they were a relatively common cause of pneumococcal bacteremia in this center treating a high volume of biliary tract illnesses.
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital, Japan; Department of Infectious Diseases, Nagoya University Graduate School of Medicine, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Morioka
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital, Japan.
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Iguchi
authors.affiliation: Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan; Department of Bacteriology, Nagoya University Graduate School of Medicine, Japan.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Oodate
authors.affiliation: Department of Psychiatry, Nagoya University Hospital, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Yoneda
authors.affiliation: Department of Respiratory Medicine and Clinical Immunology, Toyota Kosei Hospital, Japan.
authors.forename: Futoshi
authors.initials: F
authors.lastname: Ushijima
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital, Japan; Department of Infectious Diseases, Nagoya University Graduate School of Medicine, Japan.
authors.forename: Aki
authors.initials: A
authors.lastname: Hirabayashi
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital, Japan; Department of Infectious Diseases, Nagoya University Graduate School of Medicine, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Tetsuka
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital, Japan.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Tomita
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital, Japan.
authors.forename: Daizo
authors.initials: D
authors.lastname: Kato
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital, Japan; Department of Infectious Diseases, Nagoya University Graduate School of Medicine, Japan. Electronic address: tyagi@med.nagoya-u.ac.jp.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yagi
mesh_terms: D000328:Adult; D000368:Aged; D001646:Bile / Q000382:microbiology; D002761:Cholangitis / Q000453:epidemiology* / Q000382:microbiology; D002764:Cholecystitis / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D012189:Retrospective Studies; D013296:Streptococcus pneumoniae
keywords: Biliary tract infection; Pneumococcal cholangitis; Pneumococcal cholecystitis; Streptococcus pneumoniae