title: Tritylation of Alcohols under Mild Conditions without Using Silver Salts.
abstract: Secondary alcohols were conveniently tritylated under mild conditions within a short running time with tritylium trifluoroacetate generated in situ from trityl alcohols and trifluoroacetic anhydride. No expensive silver salts were needed for the reactions. Four secondary alcohols were tritylated with both mono- and dimethoxy trityl alcohols giving good to excellent isolated yields. The reaction was also tested on four nucleoside derivatives that have primary alcohols. Satisfactory results were also obtained.
authors.affiliation: Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
authors.forename: Shahien
authors.initials: S
authors.lastname: Shahsavari
authors.affiliation: Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
authors.forename: Jinsen
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
authors.forename: Travis
authors.initials: T
authors.lastname: Wigstrom
authors.affiliation: Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
authors.forename: James
authors.initials: J
authors.lastname: Gooding
authors.affiliation: Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Gauronskas
authors.affiliation: Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
authors.forename: Shiyue
authors.initials: S
authors.lastname: Fang
keywords: Alcohols; Nucleosides; Protecting groups; Trifluoroacetic anhydride; Tritylation