title: Intraocular sarcoma associated with lens capsule rupture and persistent hyperplastic primary vitreous in a dog.
abstract: This case report describes the clinical findings and ocular pathology in an adult Golden Retriever diagnosed with an intraocular sarcoma. Nineteen s prior to diagnosis with a lens capsule rupture and intraocular sarcoma, the dog was diagnosed with persistent hyperplastic primary vitreous and uveitis based on clinical signs and the ultrasonographic appearance of the eye. Two years after enucleation, there was no evidence of metastatic spread of the sarcoma. The immunohistochemical characteristics of the tumor as well as the limitations and supportive evidence used in attempting to identify the histogenesis of the tumor are outlined.
authors.affiliation: Clinical Ophthalmology and Eye Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.|Ophthalmology Department, Small Animal Specialist Hospital, North Ryde, NSW, Australia.
authors.forename: Kathleen L
authors.identifier: http://orcid.org/0000-0003-2548-2969
authors.initials: KL
authors.lastname: Graham
authors.affiliation: Veterinary Pathology Diagnostic Services, University of Sydney, Sydney, NSW, Australia.
authors.forename: Mark B
authors.initials: MB
authors.lastname: Krockenberger
authors.affiliation: Ophthalmology Department, Small Animal Specialist Hospital, North Ryde, NSW, Australia.
authors.forename: F Mark
authors.initials: FM
authors.lastname: Billson
mesh_terms: D000818:Animals; D057971:Anterior Capsular Rupture, Ocular / Q000000981:diagnostic imaging / Q000209:etiology / Q000662:veterinary*; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D004285:Dogs; D005134:Eye Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000662:veterinary*; D005260:Female; D007903:Lens Capsule, Crystalline / Q000000981:diagnostic imaging; D054514:Persistent Hyperplastic Primary Vitreous / Q000150:complications / Q000000981:diagnostic imaging / Q000662:veterinary*; D012509:Sarcoma / Q000150:complications / Q000662:veterinary*; D014463:Ultrasonography / Q000662:veterinary
keywords: PHPV; canine; dog; intraocular sarcoma; lens capsule rupture; persistent hyperplastic primary vitreous