title: Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron.
authors.affiliation: Personalized Medicine Program, Mission Health, Asheville, North Carolina, USA.
authors.forename: G C
authors.initials: GC
authors.lastname: Bell
authors.affiliation: Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
authors.forename: K E
authors.initials: KE
authors.lastname: Caudle
authors.affiliation: Department of Genetics, Stanford University, Stanford, California, USA.
authors.forename: M
authors.initials: M
authors.lastname: Whirl-Carrillo
authors.affiliation: University of California, San Diego, Department of Anesthesiology, San Diego, California, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Gordon
authors.affiliation: Committee on Clinical Pharmacology and Pharmacogenomics, University of Chicago, Chicago, Illinois, USA.
authors.forename: K
authors.initials: K
authors.lastname: Hikino
authors.affiliation: Division of Human Genetics, Division of Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Prows
authors.affiliation: Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy-Kansas City, Kansas City, Missouri, USA.
authors.forename: A
authors.initials: A
authors.lastname: Gaedigk
authors.affiliation: Department of Pediatrics, University of Missouri-Kansas City, Kansas City, Missouri, USA.|Department of Pharmacology, University of Extremadura, Cáceres, Spain.
authors.forename: Jag
authors.initials: J
authors.lastname: Agundez
authors.affiliation: Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.|Department of Anesthesia, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors.forename: S
authors.initials: S
authors.lastname: Sadhasivam
authors.affiliation: Department of Genetics, Stanford University, Stanford, California, USA.
authors.forename: T E
authors.initials: TE
authors.lastname: Klein
authors.affiliation: Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany, and University of Tübingen, Germany.|Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany.|Department of Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Schwab
mesh_terms: D000932:Antiemetics / Q000494:pharmacology; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000517:prevention & control*; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D017294:Ondansetron / Q000494:pharmacology*; D010597:Pharmacogenetics / Q000379:methods; D011110:Polymorphism, Genetic; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control*; D011878:Radiotherapy / Q000009:adverse effects; D058827:Serotonin 5-HT3 Receptor Agonists / Q000494:pharmacology; D000077526:Tropisetron / Q000494:pharmacology*
chemical_list: D000932:Antiemetics; D058827:Serotonin 5-HT3 Receptor Agonists; D017294:Ondansetron; D000077526:Tropisetron; D019389:Cytochrome P-450 CYP2D6