title: Staged Suprapectoral Expander/Implant Reconstruction without Acellular Dermal Matrix following Nipple-Sparing Mastectomy.
abstract: BACKGROUND
  Since the introduction of nipple-sparing mastectomy as an oncologically safe procedure for the treatment of breast cancer, reconstructive efforts for immediate staged expander/implant reconstruction have focused on submuscular implantation with or without acellular dermal matrix. Suprapectoral reconstruction without acellular dermal matrix has received little attention in the reconstructive literature of nipple-sparing mastectomy.
  
  
  METHODS
  Between 2005 and 2015, 155 patients (250 breasts) underwent nipple-sparing mastectomy with prepectoral staged expander/implant reconstruction using thick mastectomy skin flaps without acellular dermal matrix. Patients with different breast sizes, including those patients with very large breasts who required a primary mastopexy, were considered candidates for the suprapectoral reconstruction. Tumor-related data, comorbidities, and preoperative or postoperative radiation therapy were evaluated for correlation with the final outcome.
  
  
  RESULTS
  Patients were followed up for an average of 55.5 months (range, 138.1 to 23.6 months). The tumor recurrence rate was 2.6 percent. Adverse outcomes such as capsular contracture, implant dystopia, and rippling were studied. Aesthetic outcome, based on a three-point evaluation scale, showed 53.6 percent of patients as having a very good result, 31.6 percent showing a good result, 9 percent showing a fair result, and 5.8 percent showing a poor result.
  
  
  CONCLUSIONS
  The suprapectoral two-stage expander/implant reconstruction without acellular dermal matrix in nipple-sparing mastectomy has certain advantages with respect to breast shape, less morbidity related to expansion, ease of reconstruction, and cost effectiveness. These advantages have to be weighed against those of subpectoral reconstruction with acellular dermal matrix to determine the method of choice.
  
  
  METHODS
  Therapeutic, IV.
authors.affiliation: Orange, Calif.|From St. Joseph Hospital and the Departments of Plastic Surgery and Surgery, University of California Irvine Medical Center.
authors.forename: Arthur H
authors.initials: AH
authors.lastname: Salibian
authors.affiliation: Orange, Calif.|From St. Joseph Hospital and the Departments of Plastic Surgery and Surgery, University of California Irvine Medical Center.
authors.forename: Jay K
authors.initials: JK
authors.lastname: Harness
authors.affiliation: Orange, Calif.|From St. Joseph Hospital and the Departments of Plastic Surgery and Surgery, University of California Irvine Medical Center.
authors.forename: Donald S
authors.initials: DS
authors.lastname: Mowlds
mesh_terms: D062088:Acellular Dermis; D000328:Adult; D019928:Breast Implantation / Q000295:instrumentation / Q000379:methods*; D018427:Breast Implants; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015414:Mastectomy, Subcutaneous; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011183:Postoperative Complications; D011446:Prospective Studies; D015626:Tissue Expansion / Q000295:instrumentation / Q000379:methods*; D015625:Tissue Expansion Devices