title: Oxidative Intramolecular 1,2-Amino-Oxygenation of Alkynes under AuI/AuIIICatalysis: Discovery of a Pyridinium-Oxazole Dyad as an Ionic Fluorophore.
abstract: Oxidative intramolecular 1,2-amino-oxygenation reactions, combining gold(I)/gold(III) catalysis, is reported. The reaction provides efficient access to a structurally unique ionic pyridinium-oxazole dyad with tunable emission wavelengths. The application of these fluorophores as potential biomarkers has been investigated.
authors.affiliation: Division of Organic Chemistry, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411 008, India.|Academy of Scientific and Innovative Research (AcSIR), New Delhi, 110 025, India.
authors.forename: Aslam C
authors.initials: AC
authors.lastname: Shaikh
authors.affiliation: Bioprospecting Group, Agharkar Research Institute, Pune, 411 004, India.
authors.forename: Dnyanesh S
authors.initials: DS
authors.lastname: Ranade
authors.affiliation: Central NMR Facility, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411 008, India.
authors.forename: Pattuparambil R
authors.initials: PR
authors.lastname: Rajamohanan
authors.affiliation: Bioprospecting Group, Agharkar Research Institute, Pune, 411 004, India.
authors.forename: Prasad P
authors.identifier: 0000-0002-3929-2990
authors.initials: PP
authors.lastname: Kulkarni
authors.affiliation: Division of Organic Chemistry, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, 411 008, India.|Academy of Scientific and Innovative Research (AcSIR), New Delhi, 110 025, India.
authors.forename: Nitin T
authors.identifier: 0000-0002-8372-2759
authors.initials: NT
authors.lastname: Patil
keywords: cell imaging; cyclization; fluorescent probes; gold; synthetic methods