title: Design of Bioinorganic Materials at the Interface of Coordination and Biosupramolecular Chemistry.
abstract: Protein assemblies have recently become known as potential molecular scaffolds for applications in materials science and bio-nanotechnology. Efforts to design protein assemblies for construction of protein-based hybrid materials with metal ions, metal complexes, nanomaterials and proteins now represent a growing field with a common aim of providing novel functions and mimicking natural functions. However, the important roles of protein assemblies in coordination and biosupramolecular chemistry have not been systematically investigated and characterized. In this personal account, we focus on our recent progress in rational design of protein assemblies using bioinorganic chemistry for (1) exploration of unnatural reactions, (2) construction of functional protein architectures, and (3) in vivo applications.
authors.affiliation: Department of Life Science anad Technology, Tokyo Institute of Technology, B55-Nagatsuta, Midori-ku, Yokohama, 226-8501, Japan.
authors.forename: Basudev
authors.initials: B
authors.lastname: Maity
authors.affiliation: Department of Life Science anad Technology, Tokyo Institute of Technology, B55-Nagatsuta, Midori-ku, Yokohama, 226-8501, Japan.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ueno
mesh_terms: D015195:Drug Design; D046911:Macromolecular Substances / Q000138:chemical synthesis / Q000737:chemistry; D008958:Models, Molecular; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D011506:Proteins / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D046911:Macromolecular Substances; D009942:Organometallic Compounds; D011506:Proteins
keywords: Bacteripphage T4; Bioinorganic chemistry; Protein assembly; Supramolecular chemistry; ferritin