title: High Prevalence of Middle East Respiratory Coronavirus in Young Dromedary Camels in Jordan.
abstract: Prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined in 45 dromedary camels from two geographically separated herds in Jordan. Virus shedding was only detected in swabs obtained from the respiratory tract and primarily observed in camels younger than 3 years. MERS-CoV seroprevalence increased with age of camels. Bovine and sheep sera were seronegative. Phylogenetic analysis of partial S2 clustered the Jordanian MERS-CoV strains with contemporary MERS-CoV strains associated with nosocomial outbreaks.
authors.affiliation: 1 Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Hamilton, Montana.
authors.forename: Neeltje
authors.initials: N
authors.lastname: van Doremalen
authors.affiliation: 2 Food and Agriculture Organization of the United Nations (FAO) , Amman, Jordan .
authors.forename: Zaidoun S K
authors.initials: ZS
authors.lastname: Hijazeen
authors.affiliation: 3 Veterinary Epidemiology, Economics and Public Health Group, The Royal Veterinary College , Hatfield, United Kingdom .
authors.forename: Peter
authors.initials: P
authors.lastname: Holloway
authors.affiliation: 4 Department of Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology , Irbid, Jordan .
authors.forename: Bilal
authors.initials: B
authors.lastname: Al Omari
authors.affiliation: 5 Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University , Manhattan, Kansas.
authors.forename: Chester
authors.initials: C
authors.lastname: McDowell
authors.affiliation: 6 Department of Microbiology, Immunology, and Pathology, Colorado State University , Fort Collins, Colorado.
authors.forename: Danielle
authors.initials: D
authors.lastname: Adney
authors.affiliation: 4 Department of Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology , Irbid, Jordan .
authors.forename: Hani A
authors.initials: HA
authors.lastname: Talafha
authors.affiliation: 3 Veterinary Epidemiology, Economics and Public Health Group, The Royal Veterinary College , Hatfield, United Kingdom .
authors.forename: Javier
authors.initials: J
authors.lastname: Guitian
authors.affiliation: 7 Department of Microbiology and Immunology, Emory University School of Medicine , Atlanta, Georgia .
authors.forename: John
authors.initials: J
authors.lastname: Steel
authors.affiliation: 8 Boehringer Ingelheim , MENA, Dubai, United Arab Emirates .
authors.forename: Nadim
authors.initials: N
authors.lastname: Amarin
authors.affiliation: 9 FAO Regional Office for the Near East and North Africa , Cairo, Egypt .
authors.forename: Markos
authors.initials: M
authors.lastname: Tibbo
authors.affiliation: 4 Department of Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology , Irbid, Jordan .
authors.forename: Ehab
authors.initials: E
authors.lastname: Abu-Basha
authors.affiliation: 4 Department of Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology , Irbid, Jordan .
authors.forename: Ahmad M
authors.initials: AM
authors.lastname: Al-Majali
authors.affiliation: 1 Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Hamilton, Montana.
authors.forename: Vincent J
authors.initials: VJ
authors.lastname: Munster
authors.affiliation: 5 Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University , Manhattan, Kansas.
authors.forename: Juergen A
authors.initials: JA
authors.lastname: Richt
mesh_terms: D000375:Aging; D000818:Animals; D002162:Camelus / Q000821:virology*; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000821:virology; D018352:Coronavirus Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D007597:Jordan / Q000453:epidemiology; D065207:Middle East Respiratory Syndrome Coronavirus / Q000302:isolation & purification*; D015995:Prevalence; D012367:RNA, Viral / Q000235:genetics; D016036:Seroepidemiologic Studies; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology / Q000821:virology; D017201:Virus Shedding
chemical_list: D012367:RNA, Viral
keywords: Jordan; MERS-CoV; dromedary camel; phylogeny; serology