title: Accurate measurement of JHHin overlapped signals by a TOCSY-edited SERF Experiment.
abstract: Selective refocusing (GSERF or the recent PSYCHEDELIC) experiments were originally designed to determine all proton-proton coupling constants (JHH) for a selected proton resonance. They work for isolated signals on which selective excitation can be successfully applied but, as it happens in other selective experiments, fail for overlapped signals. To circumvent this limitation, a doubly-selective TOCSY-GSERF scheme is presented for the measurement of JHHin protons resonating in crowded regions. This new experiment takes advantage of the editing features of an initial TOCSY transfer to uncover hidden resonances that become accessible to perform the subsequent frequency-selective refocusing. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Servei de Ressonància Magnètica Nuclear, Facultat de Ciències, Universitat Autònoma de Barcelona, E-08193, Bellaterra (Barcelona), Catalonia, Spain.
authors.forename: André
authors.initials: A
authors.lastname: Fredi
authors.affiliation: Servei de Ressonància Magnètica Nuclear, Facultat de Ciències, Universitat Autònoma de Barcelona, E-08193, Bellaterra (Barcelona), Catalonia, Spain.
authors.forename: Pau
authors.identifier: http://orcid.org/0000-0003-2360-1709
authors.initials: P
authors.lastname: Nolis
authors.affiliation: Servei de Ressonància Magnètica Nuclear, Facultat de Ciències, Universitat Autònoma de Barcelona, E-08193, Bellaterra (Barcelona), Catalonia, Spain.
authors.forename: Teodor
authors.identifier: http://orcid.org/0000-0002-1914-2709
authors.initials: T
authors.lastname: Parella
keywords: GSERF; J-resolved; PSYCHE; PSYCHEDELIC; proton-proton coupling constants; selective TOCSY