title: Single cardiac cycle three-dimensional intracoronary optical coherence tomography.
abstract: While high-speed intracoronary optical coherence tomography (OCT) provides three-dimensional (3D) visualization of coronary arteriesin vivo, imaging speeds remain insufficient to avoid motion artifacts induced by heartbeat, limiting the clinical utility of OCT. In this paper, we demonstrate development of a high-speed intracoronary OCT system (frame rate: 500 frames/s, pullback speed: 100 mm/s) along with prospective electrocardiogram (ECG) triggering technology, which enabled volumetric imaging of long coronary segments within a single cardiac cycle (70 mm pullback in 0.7 s) with minimal cardiac motion artifact. This technology permitted detailed visualization of 3D architecture of the coronary arterial wall of a swinein vivoand fine structure of the implanted stent.
authors.affiliation: Department of Mechanical Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; KI for Health Science and Technology, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; These authors contributed equally to this work.
authors.forename: Tae Shik
authors.initials: TS
authors.lastname: Kim
authors.affiliation: Department of Mechanical Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; KI for Health Science and Technology, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; These authors contributed equally to this work.
authors.forename: Hyun-Sang
authors.initials: HS
authors.lastname: Park
authors.affiliation: KI for Health Science and Technology, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; Graduate School of Medical Science and Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; Currently at Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; These authors contributed equally to this work.
authors.forename: Sun-Joo
authors.initials: SJ
authors.lastname: Jang
authors.affiliation: Cardiovascular Center, Korea University Guro Hospital, 80 Guro-dong, Guro-gu, Seoul, South Korea.
authors.forename: Joon Woo
authors.initials: JW
authors.lastname: Song
authors.affiliation: Department of Mechanical Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; KI for Health Science and Technology, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; Currently at Center for Medical Metrology, Korea Research Institute of Standards and Science, 267 Gajeong-ro, Yuseong-gu, Daejeon, South Korea.
authors.forename: Han Saem
authors.initials: HS
authors.lastname: Cho
authors.affiliation: Currently at Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
authors.forename: Sunwon
authors.initials: S
authors.lastname: Kim
authors.affiliation: Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
authors.forename: Brett E
authors.initials: BE
authors.lastname: Bouma
authors.affiliation: Cardiovascular Center, Korea University Guro Hospital, 80 Guro-dong, Guro-gu, Seoul, South Korea.
authors.forename: Jin Won
authors.initials: JW
authors.lastname: Kim
authors.affiliation: Department of Mechanical Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea; KI for Health Science and Technology, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, South Korea.
authors.forename: Wang-Yuhl
authors.initials: WY
authors.lastname: Oh
keywords: (170.2150) Endoscopic imaging; (170.3880) Medical and biological imaging; (170.4500) Optical coherence tomography