title: There is no evident correlation between interleukin-10 gene polymorphisms and periportal fibrosis regression after specific treatment.
abstract: We evaluated the associations between interleukin-10 (IL-10) gene polymorphisms -G1082A/-C819T/-C592A and periportal fibrosis regression after specific treatment for schistosomiasis.
  This retrospective cohort study involved 125 Brazilian patients infected with Schistosomiasis mansoni, who were followed up for 2 years after specific treatment to estimate the probability of periportal fibrosis regression.
  There was no evidence of associations between IL-10 polymorphisms and periportal fibrosis regression after treatment.
  There was no evidence of associations between gene promoter polymorphisms of IL-10 and the regression of periportal fibrosis in this Brazilian population.
authors.affiliation: Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Vitória de Santo Antão, Pernambuco, Brazil.
authors.forename: Paula Carolina Valença
authors.initials: PC
authors.lastname: Silva
authors.affiliation: Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Vitória de Santo Antão, Pernambuco, Brazil.
authors.forename: Aline Vieira da
authors.initials: AV
authors.lastname: Silva
authors.affiliation: Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Vitória de Santo Antão, Pernambuco, Brazil.
authors.forename: Taysa Nascimento
authors.initials: TN
authors.lastname: Silva
authors.affiliation: Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Vitória de Santo Antão, Pernambuco, Brazil.
authors.forename: Letícia Moura de
authors.initials: LM
authors.lastname: Vasconcelos
authors.affiliation: Laboratório de Biologia Molecular, Centro de Oncohematologia Pediátrica, Hospital Universitário Oswaldo Cruz, Universidade de Pernambuco, Recife, Pernambuco, Brazil.|Instituto de Ciências Biológicas, Universidade de Pernambuco, Recife, Pernambuco, Brazil.
authors.forename: Adriana Vieira
authors.initials: AV
authors.lastname: Gomes
authors.affiliation: Setor de Virologia do Laboratório de Imunopatologia Keizo-Asami, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.|Departamento de Fisiologia e Farmacologia, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
authors.forename: Maria Rosângela Cunha Duarte
authors.initials: MR
authors.lastname: Coêlho
authors.affiliation: Laboratório de Biologia Molecular, Centro de Oncohematologia Pediátrica, Hospital Universitário Oswaldo Cruz, Universidade de Pernambuco, Recife, Pernambuco, Brazil.|Instituto de Ciências Biológicas, Universidade de Pernambuco, Recife, Pernambuco, Brazil.|Faculdade de Ciências Médicas, Universidade de Pernambuco, Recife, Pernambuco, Brazil.
authors.forename: Maria Tereza Cartaxo
authors.initials: MT
authors.lastname: Muniz
authors.affiliation: Departamento de Medicina Clínica, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
authors.forename: Ana Lúcia Coutinho
authors.initials: AL
authors.lastname: Domingues
mesh_terms: D006801:Humans; D016753:Interleukin-10 / Q000235:genetics*; D056627:Peritoneal Fibrosis / Q000188:drug therapy / Q000235:genetics* / Q000469:parasitology; D011110:Polymorphism, Genetic; D012189:Retrospective Studies; D012555:Schistosomiasis mansoni / Q000150:complications*; D012720:Severity of Illness Index
chemical_list: D016753:Interleukin-10