title: Hemocompatibility of Superhemophobic Titania Surfaces.
abstract: The hemocompatibility of superhemophobic surfaces is investigated and compared with that of hemophobic surfaces and hemophilic surfaces. This analysis indicates that only those superhemophobic surfaces with a robust Cassie-Baxter state display significantly lower platelet adhesion and activation. It is envisioned that the understanding gained through this work will lead to the fabrication of improved hemocompatible, superhemophobic medical implants.
authors.affiliation: Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.
authors.forename: Sanli
authors.initials: S
authors.lastname: Movafaghi
authors.affiliation: Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.
authors.forename: Victoria
authors.initials: V
authors.lastname: Leszczak
authors.affiliation: Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Sorkin
authors.affiliation: Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.|School of Biomedical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.|Department of Biomedical Engineering, Dorothy Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210, USA.
authors.forename: Lakshmi P
authors.initials: LP
authors.lastname: Dasi
authors.affiliation: Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.|School of Biomedical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.
authors.forename: Ketul C
authors.initials: KC
authors.lastname: Popat
authors.affiliation: Department of Mechanical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.|School of Biomedical Engineering, Colorado State University, Fort Collins, CO, 80523, USA.
authors.forename: Arun K
authors.initials: AK
authors.lastname: Kota
mesh_terms: D001792:Blood Platelets / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D008422:Materials Testing; D010973:Platelet Adhesiveness / Q000187:drug effects*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: C009495:titanium dioxide; D014025:Titanium
keywords: biomaterial; hemocompatible; platelet adhesion and activation; superhemophobic; superhydrophobic; titanium-based implants