title: Quantification of human upper extremity nerves and fascicular anatomy.
abstract: In this study we provide detailed quantification of upper extremity nerve and fascicular anatomy. The purpose is to provide values and trends in neural features useful for clinical applications and neural interface device design.
  
  
  
  Nerve cross-sections were taken from 4 ulnar, 4 median, and 3 radial nerves from 5 arms of 3 human cadavers. Quantified nerve features included cross-sectional area, minor diameter, and major diameter. Fascicular features analyzed included count, perimeter, area, and position.
  
  
  
  Mean fascicular diameters were 0.57 ± 0.39, 0.6 ± 0.3, 0.5 ± 0.26 mm in the upper arm and 0.38 ± 0.18, 0.47 ± 0.18, 0.4 ± 0.27 mm in the forearm of ulnar, median, and radial nerves, respectively. Mean fascicular diameters were inversely proportional to fascicle count.
  
  
  
  Detailed quantitative anatomy of upper extremity nerves is a resource for design of neural electrodes, guidance in extraneural procedures, and improved neurosurgical planning. Muscle Nerve 56: 463-471, 2017.
authors.affiliation: Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44104, USA.
authors.forename: Natalie A
authors.initials: NA
authors.lastname: Brill
authors.affiliation: Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44104, USA.|Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
authors.forename: Dustin J
authors.initials: DJ
authors.lastname: Tyler
mesh_terms: D001132:Arm / Q000033:anatomy & histology* / Q000294:innervation*; D002102:Cadaver; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000033:anatomy & histology*; D010525:Peripheral Nerves / Q000033:anatomy & histology; D011826:Radial Nerve / Q000033:anatomy & histology*; D014459:Ulnar Nerve / Q000033:anatomy & histology*; D034941:Upper Extremity / Q000033:anatomy & histology / Q000294:innervation
keywords: fascicles; intraneural topography; nerve dimensions; nerve surgery; neural anatomy; neuroprosthesis; peripheral nerve