title: Sifting through CD8+T Cell Memory.
abstract: In this issue of Immunity, Gerlach et al. (2016) describe three distinct memory CD8+T cell subsets based upon expression of the fractalkine receptor CX3CR1. Their findings revise the paradigm of effector and central memory T cells by revealing a subset of CD8+memory T cells defined by intermediate levels of expression of CX3CR1 that conducts tissue surveillance.
authors.affiliation: Department of Pathology, University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Martin
authors.affiliation: Department of Pathology, University of Iowa, Iowa City, IA 52242, USA; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA 52242, USA. Electronic address: vladimir-badovinac@uiowa.edu.
authors.forename: Vladimir P
authors.initials: VP
authors.lastname: Badovinac
mesh_terms: D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D007156:Immunologic Memory / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology