title: Synchrotron radiation micro X-ray fluorescence spectroscopy of thin structures in bone samples: comparison of confocal and color X-ray camera setups.
abstract: In the quest for finding the ideal synchrotron-radiation-induced imaging method for the investigation of trace element distributions in human bone samples, experiments were performed using both a scanning confocal synchrotron radiation micro X-ray fluorescence (SR-µXRF) (FLUO beamline at ANKA) setup and a full-field color X-ray camera (BAMline at BESSY-II) setup. As zinc is a trace element of special interest in bone, the setups were optimized for its detection. The setups were compared with respect to count rate, required measurement time and spatial resolution. It was demonstrated that the ideal method depends on the element of interest. Although for Ca (a major constituent of the bone with a low energy of 3.69 keV for its Kα XRF line) the color X-ray camera provided a higher resolution in the plane, for Zn (a trace element in bone) only the confocal SR-µXRF setup was able to sufficiently image the distribution.
authors.affiliation: Atominstitut, TU Wien, Vienna, Austria.
authors.forename: M
authors.initials: M
authors.lastname: Rauwolf
authors.affiliation: Atominstitut, TU Wien, Vienna, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Turyanskaya
authors.affiliation: Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Vienna, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Roschger
authors.affiliation: Atominstitut, TU Wien, Vienna, Austria.
authors.forename: J
authors.initials: J
authors.lastname: Prost
authors.affiliation: Forschungszentrum Karlsruhe/KIT, Institute for Synchrotron Radiation, ANKA, Karlsruhe, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Simon
authors.affiliation: IFG Institute of Scientific Instruments GmbH, Berlin, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Scharf
authors.affiliation: Department of Analytical Chemistry, Bundesanstalt fuer Materialforschung und -pruefung, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Radtke
authors.affiliation: Department of Analytical Chemistry, Bundesanstalt fuer Materialforschung und -pruefung, Berlin, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Schoonjans
authors.affiliation: Department of Analytical Chemistry, Bundesanstalt fuer Materialforschung und -pruefung, Berlin, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Guilherme Buzanich
authors.affiliation: Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Vienna, Austria.
authors.forename: K
authors.initials: K
authors.lastname: Klaushofer
authors.affiliation: Atominstitut, TU Wien, Vienna, Austria.
authors.forename: P
authors.initials: P
authors.lastname: Wobrauschek
authors.affiliation: Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Vienna, Austria.
authors.forename: J G
authors.initials: JG
authors.lastname: Hofstaetter
authors.affiliation: Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Vienna, Austria.
authors.forename: P
authors.initials: P
authors.lastname: Roschger
authors.affiliation: Atominstitut, TU Wien, Vienna, Austria.
authors.forename: C
authors.initials: C
authors.lastname: Streli
mesh_terms: D001842:Bone and Bones / Q000737:chemistry*; D006801:Humans; D013052:Spectrometry, X-Ray Emission; D017356:Synchrotrons; D014131:Trace Elements; D014965:X-Rays; D015032:Zinc
chemical_list: D014131:Trace Elements; D015032:Zinc
keywords: SR-µXRF; color X-ray camera; confocal; human bone