title: Relapsed Wilms' tumor with multiple brain metastasis.
abstract: Wilms' tumor is the most common malignant renal tumor in childhood. The brain metastasis of a Wilms' tumor with anaplastic histopathology is rare. We present the case of an 8-year-old girl with Wilms' tumor, who presented with multiple brain metastases 5 years after her primary diagnosis. The brain masses were diagnosed after a generalized tonic-clonic seizure attack. The big solid mass in the cerebellum was resected, and whole-brain radiotherapy was performed, after which, she succumbed to her disease. In the case of clinical suspicion, cranial surveillance should be included in the routine clinical work-up for Wilms' tumor. Combined aggressive therapy (surgery+radiotherapy+chemotherapy) should be applied whenever possible, for both better survival and palliative aspects.
authors.affiliation: Department of Neurosurgery, Bahçeşehir University Medical Faculty, Istanbul, Turkey.
authors.forename: Akın
authors.initials: A
authors.lastname: Akakın
authors.affiliation: Department of Neurosurgery, Bahçeşehir University Medical Faculty, Istanbul, Turkey.
authors.forename: Baran
authors.initials: B
authors.lastname: Yılmaz
authors.affiliation: Department of Orthopedic Surgery-Spine Center, University of California at San Francisco, San Francisco, CA, USA.
authors.forename: Murat Şakir
authors.initials: MŞ
authors.lastname: Ekşi
authors.affiliation: Department of Pathology, Bahçeşehir University Medical Faculty, Istanbul, Turkey.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Yapıcıer
authors.affiliation: Department of Neurosurgery, Bahçeşehir University Medical Faculty, Istanbul, Turkey.
authors.forename: Türker
authors.initials: T
authors.lastname: Kılıç
keywords: Chemotherapy; Metastasis; Radiotherapy; Surgery; Wilms tumor