title: Palladium-Mediated Labeling of Nucleic Acids.
abstract: New applications of Pd-catalyzed coupling reactions (Suzuki-Miyaura, Sonogashira, and Stille-Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.
authors.affiliation: Université Grenoble Alpes, CNRS, Département de Chimie Moléculaire, UMR 5250, B. P. 53, 38041, Grenoble Cedex 9, France.
authors.forename: Eric
authors.identifier: 0000-0002-3911-6241
authors.initials: E
authors.lastname: Defrancq
authors.affiliation: Université Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire CoSMIT, Equipe Labellisée Ligue Contre Le Cancer, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, 92296, France.
authors.forename: Samir
authors.identifier: 0000-0002-4994-9001
authors.initials: S
authors.lastname: Messaoudi
mesh_terms: D002384:Catalysis; D015341:Nucleic Acid Probes / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013194:Staining and Labeling
chemical_list: D015341:Nucleic Acid Probes; D010165:Palladium
keywords: Suzuki-Miyaura; cross-coupling; nucleic acids; oligonucleotides; palladium