title: Benefit-risk ratio of canned pacific saury (Cololabis saira) intake: Essential fatty acids vs. heavy metals.
abstract: Fatty acid (FA) and element contents were studied in 14 brands of canned (in its own juice and with sunflower oil) saury (Cololabis saira), a popular product of Russian market. Canned saury is a valuable source of essential polyunsaturated FA - eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). To obtain personal daily dose of EPA + DHA of 1 g for prevention of cardiovascular diseases, neural and inflammatory disorders one needs to intake from 26 to 76 g of canned saury, as was calculated for studied brands. ICP-OES analysis of 24 elements showed that Pb concentration in one brand and Cd content in most of studied saury samples exceeded standards for fish meat established by the European Commission. However, values of hazard quotient, HQEFA,which estimate benefit-risk ratio of fish intake, indicate that canned saury is safe product for human nutrition.
authors.affiliation: Institute of Biophysics SB RAS, Federal Research Center "Krasnoyarsk Science Center SB RAS", Akademgorodok, 50/50, Krasnoyarsk, 660036, Russia. Electronic address: hydrakr@rambler.ru.
authors.forename: O V
authors.initials: OV
authors.lastname: Anishchenko
authors.affiliation: Institute of Biophysics SB RAS, Federal Research Center "Krasnoyarsk Science Center SB RAS", Akademgorodok, 50/50, Krasnoyarsk, 660036, Russia; Siberian Federal University, 79 Svobodny av., Krasnoyarsk, 660041, Russia. Electronic address: labehe@ibp.ru.
authors.forename: N N
authors.initials: NN
authors.lastname: Sushchik
authors.affiliation: Institute of Biophysics SB RAS, Federal Research Center "Krasnoyarsk Science Center SB RAS", Akademgorodok, 50/50, Krasnoyarsk, 660036, Russia; Siberian Federal University, 79 Svobodny av., Krasnoyarsk, 660041, Russia. Electronic address: makhutova@ibp.krasn.ru.
authors.forename: O N
authors.initials: ON
authors.lastname: Makhutova
authors.affiliation: Institute of Biophysics SB RAS, Federal Research Center "Krasnoyarsk Science Center SB RAS", Akademgorodok, 50/50, Krasnoyarsk, 660036, Russia. Electronic address: kalach@ibp.ru.
authors.forename: G S
authors.initials: GS
authors.lastname: Kalachova
authors.affiliation: Institute of Biophysics SB RAS, Federal Research Center "Krasnoyarsk Science Center SB RAS", Akademgorodok, 50/50, Krasnoyarsk, 660036, Russia. Electronic address: gribov@ibp.ru.
authors.forename: I V
authors.initials: IV
authors.lastname: Gribovskaya
authors.affiliation: Federal Regional Center for Standardization, Metrology and Testing in the Krasnoyarsk Region, 1a Vavilov Str., Krasnoyarsk, 660093, Russia. Electronic address: morgun@krascsm.ru.
authors.forename: V N
authors.initials: VN
authors.lastname: Morgun
authors.affiliation: Institute of Biophysics SB RAS, Federal Research Center "Krasnoyarsk Science Center SB RAS", Akademgorodok, 50/50, Krasnoyarsk, 660036, Russia; Siberian Federal University, 79 Svobodny av., Krasnoyarsk, 660041, Russia. Electronic address: glad@ibp.ru.
authors.forename: M I
authors.initials: MI
authors.lastname: Gladyshev
mesh_terms: D000818:Animals; D005228:Fatty Acids, Essential / Q000008:administration & dosage* / Q000032:analysis*; D005399:Fishes / Q000378:metabolism*; D006801:Humans; D019216:Metals, Heavy / Q000008:administration & dosage* / Q000032:analysis*; D018570:Risk Assessment / Q000706:statistics & numerical data*; D012449:Safety
chemical_list: D005228:Fatty Acids, Essential; D019216:Metals, Heavy
keywords: Benefit-risk ratio; Canned fish; Heavy metals; Polyunsaturated fatty acids (PUFA)