title: Adsorption of pharmaceuticals in water through lignocellulosic fibers synergism.
abstract: The contamination of water from disposal of drugs is an emerging problem due to their consequences on trophic webs. This study evaluated the ability of sugarcane and coconut fiber to reduce water toxicity contaminated by pharmaceuticals. The toxicity of solutions containing pharmaceuticals was studied by bioassay using Allium cepa, before and after filtration of contaminated water. The coconut and sugarcane fiber have not been satisfactory in reducing toxicity when tested separately. Despite no induction of chromosomal aberrations, our study found a reduction of the mitotic index. The mixture of fibers showed better results providing total reduction of toxicity, in addition to maintenance in the mitotic index and induction of chromosome aberrations. The interaction between fibers and drugs was confirmed by Thermogravimetry and Differential Thermal Analyses (TG/DTA) which presented differences in profile between the fibers before and after adsorption. The mixture of coconut and sugarcane proved viable for reduction of toxicity in contaminated water by a mixture of pharmaceuticals.
authors.affiliation: Graduate Program in Industrial Biotechnology at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil.
authors.forename: Tatiana Rojo
authors.initials: TR
authors.lastname: Moro
authors.affiliation: Graduate Program in Industrial Biotechnology at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil; Graduate Program in Environmental Management at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil.
authors.forename: Francini Reis
authors.initials: FR
authors.lastname: Henrique
authors.affiliation: Graduate Program in Industrial Biotechnology at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil; Graduate Program in Environmental Management at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil.
authors.forename: Lucca Centa
authors.initials: LC
authors.lastname: Malucelli
authors.affiliation: Graduate Program in Environmental Management at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil.
authors.forename: Cíntia Mara Ribas
authors.initials: CMR
authors.lastname: de Oliveira
authors.affiliation: Graduate Program in Industrial Biotechnology at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil; Graduate Program in Environmental Management at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil.
authors.forename: Marco Aurélio
authors.initials: MA
authors.lastname: da Silva Carvalho Filho
authors.affiliation: Graduate Program in Industrial Biotechnology at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil; Graduate Program in Environmental Management at Universidade Positivo, Pedro Viriato Parigot de Souza, 5300 Campo Comprido, Curitiba, PR 81280-330, Brazil. Electronic address: evasconcelos@up.edu.br.
authors.forename: Eliane Carvalho
authors.initials: EC
authors.lastname: de Vasconcelos
mesh_terms: D000327:Adsorption; D001681:Biological Assay; D002869:Chromosome Aberrations / Q000187:drug effects*; D008031:Lignin / Q000737:chemistry*; D008940:Mitotic Index; D019697:Onions / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000302:isolation & purification* / Q000378:metabolism; D018517:Plant Roots / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D014867:Water; D014874:Water Pollutants, Chemical / Q000302:isolation & purification* / Q000633:toxicity
chemical_list: D004364:Pharmaceutical Preparations; D014874:Water Pollutants, Chemical; D014867:Water; C036909:lignocellulose; D008031:Lignin
keywords: Allium cepa; Biomass; Coconut fiber; Cytotoxicity; Genotoxicity; Sugarcane fiber