title: Effect of aerobic exercise on the atherogenic index of plasma in middle-aged Chinese men with various body weights.
abstract: OBJECTIVE
  The aim of this study was to examine the correlation between aerobic exercise and the atherogenic index of plasma (AIP) in middle-aged Chinese men stratified by body weight.
  
  
  METHODS
  A cross-sectional study, which recruited 26,701 middle-aged Chinese men undergoing health examinations in our hospital from 1st January 2014 to 30th June 2015 was performed, and the associations between body weight and AIP, and aerobic exercise and AIP were evaluated.
  
  
  RESULTS
  The mean AIP levels were -0.016±0.305, 0.138±0.3171 and 0.211±0.3243 in normal weight, overweight and obese subjects, respectively, and appeared to rise with body weight. Significantly higher AIP levels were observed in subjects with a weekly aerobic exercise period ≥90min than in those with a weekly aerobic exercise period <90min, and the mean AIP levels were -0.038±0.3015, 0.117±0.3182 and 0.192±0.3209, and were 0.003±0.3067, 0.156±0.3149 and 0.225±0.3263 in normal weight, overweight and obese men with a weekly aerobic exercise period ≥90min and <90min, respectively. In addition, aerobic exercise significantly reduced AIP after adjustment for age, systolic blood pressure, diastolic blood pressure, body mass index (BMI), fasting blood glucose and uric acid.
  
  
  CONCLUSIONS
  Lowering body weight and/or increasing aerobic exercise time may reduce AIP, and lowering body weight results in a greater reduction in AIP than aerobic exercise. Weight control combined with increased aerobic exercise time may cause a synergistic effect on the reduction of AIP.
authors.affiliation: Wuxi No.2 People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, China.
authors.forename: Shiwei
authors.initials: S
authors.lastname: Shen
authors.affiliation: The Taihu Rehabilitation Hospital of Jiangsu Province, Wuxi, Jiangsu 214086, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Wuxi Rehabilitation Hospital, Wuxi, Jiangsu 214043, China.
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Dang
authors.affiliation: Jiangsu Provincial Research Center for Health Assessment and Intervention, Wuxi, Jiangsu 214086, China.
authors.forename: Huajin
authors.initials: H
authors.lastname: Qi
authors.affiliation: Jiangsu Provincial Research Center for Health Assessment and Intervention, Wuxi, Jiangsu 214086, China. Electronic address: shentaihu222@163.com.
authors.forename: Zhenhai
authors.initials: Z
authors.lastname: Shen
authors.affiliation: Zhongguancun Xinzhiyuan Health Management Institute, Beijing 100142, China. Electronic address: wuliuxin_2015@163.com.
authors.forename: Liuxin
authors.initials: L
authors.lastname: Wu
authors.affiliation: The Taihu Rehabilitation Hospital of Jiangsu Province, Wuxi, Jiangsu 214086, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.affiliation: Wuxi No.2 People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, China.
authors.forename: Chengjian
authors.initials: C
authors.lastname: Yang
authors.affiliation: Zhongguancun Xinzhiyuan Health Management Institute, Beijing 100142, China.
authors.forename: Dongchang
authors.initials: D
authors.lastname: Qiang
authors.affiliation: Wuxi Rehabilitation Hospital, Wuxi, Jiangsu 214043, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Jiangsu Provincial Research Center for Health Assessment and Intervention, Wuxi, Jiangsu 214086, China.
authors.forename: Kedong
authors.initials: K
authors.lastname: Shui
authors.affiliation: The Taihu Rehabilitation Hospital of Jiangsu Province, Wuxi, Jiangsu 214086, China.
authors.forename: Yanying
authors.initials: Y
authors.lastname: Bao
mesh_terms: D000328:Adult; D044466:Asian People; D050197:Atherosclerosis / Q000097:blood*; D001786:Blood Glucose; D015992:Body Mass Index; D002681:China; D003430:Cross-Sectional Studies; D015444:Exercise; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000150:complications* / Q000517:prevention & control
chemical_list: D001786:Blood Glucose
keywords: Aerobic exercise; Atherogenic index of plasma (AIP); Body weight; Intervention strategy