title: CHANGES IN TOOTH HARD TISSUE MINERALI-ZATION AND BLOOD RHEOLOGY IN HEALTHY ADOLESCENTS AND THOSE WITH THYROID DYSFUNCTION.
abstract: Thyroid dysfunction causes spreading and development of caries in the teeth and changes in periodontal tissues. In addition, it causes changes in peripheral blood flow and mineralization, local transcapillary metabolism causes changes in blood rheology. There are only few works in this direction and, therefore, the purpose of our research was to find out how the mineralization and the rheological properties of blood are changed in lesion of periodontal tissue on a background of thyroid dysfunction. Accordingly, the stomatological study was conducted in 75 adolescents aged 12-18 years by the standard method, recommended by the World Health Organization. According to the study, 45 patients out of them suffered from thyroid dysfunction, in particular from hypothyroidism. The comparator group consisted of 30 children of the same age without endocrine abnormalities. By the gained results it is noted that in spite of different type lesions due to dental caries, the caries incidence and intensiveness is higher in children with hypothyroidism as compared to healthy children. Decrease in saliva excretion rate and increase in oral fluid viscosity was found in children with thyroid and endocrine diseases as compared to healthy children. In children with endocrine disorders concurrent increase in calcium content (1,43±0,08 mmol/l) and decrease in inorganic phosphate concentrations (4,54±0,15 mmol/l) is reliably established. In children with thyroid disfunction and while periodontal tissue pathology, rheological features are disordered more dramatically than in healthy children. Therefore, it can be said that the changes in the adolescents' thyroid function is one of the reasons for formation of periodontal tissue diseases.Therefore, at detecting even the first signs of the periodontal tissue diseases, it is desirable in adolescents to assess the thyroid functional condition, since it will be the precondition for effective treatment and management of dental disease, in particular, dental caries and lesions of periodontal tissue.
authors.affiliation: Polyclinic «Energy +» Ltd; I. Beritashvili Experimental Biomedical Center, Tbilisi, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Beriashvili
authors.affiliation: Polyclinic «Energy +» Ltd; I. Beritashvili Experimental Biomedical Center, Tbilisi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Nikolaishvili
authors.affiliation: Polyclinic «Energy +» Ltd; I. Beritashvili Experimental Biomedical Center, Tbilisi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Mantskava
authors.affiliation: Polyclinic «Energy +» Ltd; I. Beritashvili Experimental Biomedical Center, Tbilisi, Georgia.
authors.forename: N
authors.initials: N
authors.lastname: Momtsemlidze
authors.affiliation: Polyclinic «Energy +» Ltd; I. Beritashvili Experimental Biomedical Center, Tbilisi, Georgia.
authors.forename: K
authors.initials: K
authors.lastname: Franchuk
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D003731:Dental Caries / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D005891:Gingivitis / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications / Q000503:physiopathology; D010518:Periodontitis / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D012212:Rheology; D013959:Thyroid Diseases / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D014074:Tooth Calcification