title: Review of the Clinical Evidence for the Use of DEBIRI in the Treatment of Colorectal Metastatic Disease.
abstract: Colorectal cancer is a common malignancy that most commonly metastasizes to the liver. There has been considerable effort in developing new treatment options for these patients. One method that has been developed for the treatment of colorectal metastases to the liver is irinotecan-loaded drug-eluting bead (DEBIRI) embolization. This article reviews the current literature on DEBIRI and discusses the state of current knowledge and possible areas of future investigation.
authors.affiliation: Department of Radiology, Division of Interventional Radiology, University of Minnesota, 420 Delaware St SE, MMC 292, Minneapolis, MN, 55455, USA. youn1862@umn.edu.
authors.forename: Shamar
authors.initials: S
authors.lastname: Young
authors.affiliation: Department of Radiology, Division of Interventional Radiology, University of Minnesota, 420 Delaware St SE, MMC 292, Minneapolis, MN, 55455, USA.
authors.forename: Donna
authors.initials: D
authors.lastname: D'Souza
authors.affiliation: Department of Radiology, Division of Interventional Radiology, University of Minnesota, 420 Delaware St SE, MMC 292, Minneapolis, MN, 55455, USA.
authors.forename: Siobhan
authors.initials: S
authors.lastname: Flanagan
authors.affiliation: Department of Radiology, Division of Interventional Radiology, University of Minnesota, 420 Delaware St SE, MMC 292, Minneapolis, MN, 55455, USA.
authors.forename: Jafar
authors.initials: J
authors.lastname: Golzarian
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D000077146:Irinotecan; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D002166:Camptothecin
keywords: Colon cancer; Drug elutting beads; Transarterial chemoembolization (TACE)