title: Outcomes and Radiographic Findings of Isolated Spontaneous Superior Mesenteric Artery Dissection.
abstract: OBJECTIVE
  This study aimed to investigate the features, treatments, and prognosis of patients with symptomatic and asymptomatic isolated SMA dissection.
  
  
  METHODS
  Data from 35 consecutive patients in whom isolated SMA dissection was diagnosed on computed tomography angiography (CTA) between 2004 and 2015 at two general hospitals in Japan, were collected retrospectively. Nineteen symptomatic patients were compared, and 16 asymptomatic patients with incidentally revealed SMA dissection were also compared. In addition, the vascular remodelling and outcomes during follow-up were evaluated.
  
  
  RESULTS
  The patient characteristics in the symptomatic and incidental groups were comparable except for age; mean ages were 55.9 ± 13.9 and 65.3 ± 10.9 years, respectively. Most of the symptomatic patients were managed conservatively (including antiplatelet therapy, anticoagulants, blood pressure control, or bowel rest). In addition, one patient was initially treated by endovascular intervention because of intestinal ischaemia, and another was switched from conservative to surgical treatment. The in-hospital outcome was good with no mortality. In the incidental group, all 16 patients were observed as outpatients without additional treatment. Complete remodelling of the false lumen was observed in 31% of patients with follow-up CTA, and was associated with the presence of symptoms and the absence of false lumen with blood flow at diagnosis. Neither recurrent or new onset abdominal pain, intervention for SMA dissection, nor SMA related death was observed in either group during the follow-up period (750 ± 779 and 1200 ± 951 days).
  
  
  CONCLUSIONS
  The characteristics of asymptomatic patients with incidentally revealed SMA dissection were comparable with those of symptomatic patients, except for age. During follow-up, factors favouring complete remodelling of false lumens were the presence of symptoms, and the absence of false lumen blood flow at diagnosis.
authors.affiliation: Cardiovascular Centre, the Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kimura
authors.affiliation: Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address: takao-kato@kitano-hp.or.jp.
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.affiliation: Department of Cardiovascular Centre, Osaka Red Cross Hospital, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nagao
authors.affiliation: Cardiovascular Centre, the Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Izumi
authors.affiliation: Cardiovascular Centre, the Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Haruna
authors.affiliation: Cardiovascular Centre, the Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ueyama
authors.affiliation: Department of Cardiovascular Centre, Osaka Red Cross Hospital, Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Inada
authors.affiliation: Cardiovascular Centre, the Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Inoko
mesh_terms: D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D002317:Cardiovascular Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000072226:Computed Tomography Angiography; D057510:Endovascular Procedures / Q000009:adverse effects; D005260:Female; D006769:Hospitals, General; D006801:Humans; D033162:Incidental Findings; D007564:Japan; D008297:Male; D017538:Mesenteric Artery, Superior / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D066253:Vascular Remodeling; D014656:Vascular Surgical Procedures / Q000009:adverse effects
chemical_list: D002317:Cardiovascular Agents
keywords: Asymptomatic; Isolated; Prognosis; Spontaneous; Superior mesenteric artery dissection