title: [Assessment of antibiotic prophylaxis adequacy in rectal surgery].
abstract: OBJECTIVE
  Antibiotic prophylaxis is the most suitable tool for preventing surgical site infection (SSI), so the development of guidelines and assessment of its monitoring is essential. In this study protocol compliance of antibiotic prophylaxis in rectal surgery and the effect of its adequacy in terms of pre-ention of SSI was assessed.
  
  
  METHODS
  Prospective cohort study was conducted from 1 January 2009 to 30 December 2015. The degree of compliance with antibiotic prophylaxis and causes of non-compliance in rectal surgery was evaluated. The incidence of SSI was studied after a maximum period of 30 days of incubation. To assess the effect of prophylaxis non-compliance on SSI the relative risk (RR) adjusted with the aid of a logistic regression model was used.
  
  
  RESULTS
  The study covered a total of 244 patients. The patients infected reached 20 cases with a SSI cumulative incidence of 8.2% (CI95%: 4.8-11.6). Antibiotic prophylaxis was indicated in all patients and was administered in 98% of cases, with an overall protocol compliance 92.5%. The principal cause of non-compliance was the choice of antibiotic 55.6% (n=10). The effect of inadequacy of antibiotic prophylaxis on surgical infection was RR=0.58, CI95%: 0.10-4.10 (P>0.05).
  
  
  CONCLUSIONS
  Compliance with antibiotic prophylaxis was high. No relationship between the adequacy of prophylaxis and incidence of surgical site infection in rectal surgery was found.
authors.forename: J A
authors.initials: JA
authors.lastname: Del-Moral-Luque
authors.forename: E
authors.initials: E
authors.lastname: Colás-Ruiz
authors.forename: P
authors.initials: P
authors.lastname: Gil-Yonte
authors.forename: J M
authors.initials: JM
authors.lastname: Fernández-Cebrián
authors.forename: M C
authors.initials: MC
authors.lastname: Villar-Del-Campo
authors.forename: A
authors.initials: A
authors.lastname: Delgado-Iribarren
authors.forename: J F
authors.initials: JF
authors.lastname: Valverde-Cánovas
authors.affiliation: Gil Rodríguez Caravaca, Unidad de Medicina Preventiva, Hospital Universitario Fundación Alcorcón, C/ Budapest 1, 28922 Alcorcón (Madrid) Spain. grodriguez@fhalcorcon.es.
authors.forename: G
authors.initials: G
authors.lastname: Rodríguez-Caravaca
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis / Q000592:standards*; D015331:Cohort Studies; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D019983:Guideline Adherence; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D011446:Prospective Studies; D012007:Rectum / Q000601:surgery*; D013530:Surgical Wound Infection / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents