title: CD68-Positive Cells in Hepatic Angiomyolipoma.
abstract: Four resected specimens of hepatic angiomyolipoma in which uptake of Sonazoid was observed in the postvascular phase of Sonazoid-enhanced ultrasonography were analyzed. Macrophage localization in the tumor was revealed pathologically by immunohistochemical staining for CD68. CD68-positive cells were observed in the tumor in all cases. The density of CD68-positive cells was 100/mm2, and the ratio of CD68-positive cell density in the tumor to that in the surrounding parenchyma was 32-171%. These results suggested that the uptake of the contrast agent Sonazoid was related to the density of CD68-positive cells.
authors.affiliation: Department of Clinical Laboratory Medicine, Kobe City Medical Center General Hospital, Kobe, , Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tochio
authors.forename: Eriko
authors.initials: E
authors.lastname: Tamaki
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Imai
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Iwasaki
authors.forename: Kazushi
authors.initials: K
authors.lastname: Minowa
authors.forename: Hobyung
authors.initials: H
authors.lastname: Chung
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Suginoshita
authors.forename: Tetsurou
authors.initials: T
authors.lastname: Inokuma
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kudo
mesh_terms: D000328:Adult; D000792:Angiography; D018207:Angiomyolipoma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D015703:Antigens, CD / Q000096:biosynthesis*; D015214:Antigens, Differentiation, Myelomonocytic / Q000096:biosynthesis*; D003287:Contrast Media / Q000493:pharmacokinetics; D005260:Female; D005290:Ferric Compounds / Q000493:pharmacokinetics; D006801:Humans; D007150:Immunohistochemistry; D007501:Iron / Q000493:pharmacokinetics; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D008264:Macrophages / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000493:pharmacokinetics; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D003287:Contrast Media; D005290:Ferric Compounds; D007501:Iron; D010087:Oxides; C067980:CD68 antigen, human; D000097382:CD68 Molecule; C069727:Sonazoid