title: Therapeutic Effects of Quercetin on Inflammation, Obesity, and Type 2 Diabetes.
abstract: In previous studies, abdominal obesity has been related to total low-grade inflammation and in some cases has resulted in insulin resistance and other metabolism related disorders such as diabetes. Quercetin is a polyphenol, which is a derivative of plants, and has been shownin vitroas well as in a few animal models to have several potential anti-inflammatory as well as anticarcinogenic applications. The substance has also been shown to aid in the attenuation of lipid peroxidation, platelet aggregation, and capillary permeability. However, further research is called for to gain a better understanding of how quercetin is able to provide these beneficial effects. This manuscript reviewed quercetin's anti-inflammatory properties in relation to obesity and type 2 diabetes.
authors.affiliation: College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Chen
authors.affiliation: College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
authors.forename: Hongmei
authors.identifier: 0000-0002-7305-0311
authors.initials: H
authors.lastname: Jiang
authors.affiliation: College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
authors.forename: Xiaosong
authors.initials: X
authors.lastname: Wu
authors.affiliation: College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China; Hunan Province University Key Laboratory for Agricultural Biochemistry and Biotransformation, Hunan Agricultural University, Changsha 410128, China; Hunan CoInnovation Center for Ultilization of Botanical Functional Ingredients, Changsha 410128, China.
authors.forename: Jun
authors.identifier: 0000-0001-9532-8444
authors.initials: J
authors.lastname: Fang
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000975:Antioxidants / Q000737:chemistry; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy*; D004032:Diet; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D007333:Insulin Resistance; D015227:Lipid Peroxidation; D009765:Obesity / Q000188:drug therapy*; D056128:Obesity, Abdominal / Q000188:drug therapy; D010539:Permeability; D010974:Platelet Aggregation; D011794:Quercetin / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D011794:Quercetin