title: Central nervous system filariasis masquerading as a glioma: case report.
abstract: Filariasis, an endemic zoonosis in the Southeast Asia region, has been reported to affect various organs as well as the central nervous system (CNS). Inflammatory reactions mimicking those from neoplastic lesions clinically and radiologically have been reported in the breast and urinary bladder. To date, a CNS manifestation of filarial infestation has been reported in the form of meningoencephalitis. The authors here present an interesting case of a young man presenting in status epilepticus, which on radiological evaluation appeared to be a glioma. However, postoperative histopathological examination changed the provisional diagnosis to a filarial infection of the CNS mimicking a primary CNS neoplasm.
authors.affiliation: Departments of 1 Neurosurgery and.
authors.forename: Adesh
authors.initials: A
authors.lastname: Shrivastava
authors.affiliation: Departments of 1 Neurosurgery and.
authors.forename: Prateek
authors.initials: P
authors.lastname: Arora
authors.affiliation: Pathology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, India.
authors.forename: Akriti
authors.initials: A
authors.lastname: Khare
authors.affiliation: Pathology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, India.
authors.forename: Garima
authors.initials: G
authors.lastname: Goel
authors.affiliation: Pathology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, India.
authors.forename: Neelkamal
authors.initials: N
authors.lastname: Kapoor
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis*; D020809:Central Nervous System Helminthiasis / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005368:Filariasis / Q000175:diagnosis*; D005910:Glioma / Q000175:diagnosis*; D005911:Gliosis / Q000175:diagnosis / Q000469:parasitology; D006801:Humans; D008297:Male
keywords: CNS = central nervous system; DEC = diethylcarbamazine; IHC = immunohistochemical; cerebral filariasis; glioma; gliosis; infection