title: Early diagnosis of Ehrlichia ewingii infection in a lung transplant recipient by peripheral blood smear.
abstract: Ehrlichiosis in lung transplant (LT) recipients is associated with severe outcomes. Ehrlichia ewingii is a less frequent cause of symptomatic ehrlichiosis, characterized by cytoplasmic inclusions (morulae) within circulating neutrophils. We report a case of E. ewingii infection in an LT recipient diagnosed promptly by blood smear exam and confirmed with molecular studies.
authors.affiliation: Division of Pulmonary and Critical Care, Department of Medicine, University of Missouri, Columbia, MO, USA.|Division of Infectious Diseases, Department of Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: Hariharan
authors.initials: H
authors.lastname: Regunath
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: Christian
authors.initials: C
authors.lastname: Rojas-Moreno
authors.affiliation: Department of Pathology, Member, Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, TX, USA.
authors.forename: Juan P
authors.initials: JP
authors.lastname: Olano
authors.affiliation: Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, MO, USA.
authors.forename: Richard D
authors.initials: RD
authors.lastname: Hammer
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: William
authors.initials: W
authors.lastname: Salzer
mesh_terms: D000368:Aged; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003581:Cytodiagnosis / Q000379:methods; D004269:DNA, Bacterial / Q000302:isolation & purification; D018562:Disease Transmission, Infectious; D004318:Doxycycline / Q000627:therapeutic use; D042241:Early Diagnosis; D004536:Ehrlichia / Q000302:isolation & purification*; D016873:Ehrlichiosis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005334:Fever / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006084:Graft Rejection / Q000188:drug therapy*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects* / Q000379:methods; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D026863:Ixodidae / Q000382:microbiology; D007970:Leukopenia / Q000097:blood; D016040:Lung Transplantation / Q000009:adverse effects*; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000627:therapeutic use; D009504:Neutrophils / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D016559:Tacrolimus / Q000009:adverse effects / Q000627:therapeutic use; D000069258:Thoracentesis; D013921:Thrombocytopenia / Q000097:blood; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid; D004318:Doxycycline; D011241:Prednisone; D016559:Tacrolimus
keywords: 
  Ehrlichia ewingii
  ; blood smear; doxycycline; fever; lung transplant