title: Mechanical Behavior of Cells within a Cell-Based Model of Wheat Leaf Growth.
abstract: Understanding the principles and mechanisms of cell growth coordination in plant tissue remains an outstanding challenge for modern developmental biology. Cell-based modeling is a widely used technique for studying the geometric and topological features of plant tissue morphology during growth. We developed a quasi-one-dimensional model of unidirectional growth of a tissue layer in a linear leaf blade that takes cell autonomous growth mode into account. The model allows for fitting of the visible cell length using the experimental cell length distribution along the longitudinal axis of a wheat leaf epidermis. Additionally, it describes changes in turgor and osmotic pressures for each cell in the growing tissue. Our numerical experiments show that the pressures in the cell change over the cell cycle, and in symplastically growing tissue, they vary from cell to cell and strongly depend on the leaf growing zone to which the cells belong. Therefore, we believe that the mechanical signals generated by pressures are important to consider in simulations of tissue growth as possible targets for molecular genetic regulators of individual cell growth.
authors.affiliation: Department of Systems Biology, Institute of Cytology and Genetics (ICG), Siberian Branch of Russian Academy of Science Novosibirsk, Russia.
authors.forename: Ulyana
authors.initials: U
authors.lastname: Zubairova
authors.affiliation: Department of Systems Biology, Institute of Cytology and Genetics (ICG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia; Laboratory of Analysis and Optimization of Non-Linear Systems, Institute of Computational Technologies (ICG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia.
authors.forename: Sergey
authors.initials: S
authors.lastname: Nikolaev
authors.affiliation: Laboratory of Mathematical Modeling of Hydrodynamic Processes in the Environment, Institute of Computational Mathematics and Mathematical Geophysics (ICM & MG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia; Chair of Mathematical Methods in Geophysics, Faculty of Mechanics and Mathematics, Novosibirsk State UniversityNovosibirsk, Russia.
authors.forename: Aleksey
authors.initials: A
authors.lastname: Penenko
authors.affiliation: Department of Systems Biology, Institute of Cytology and Genetics (ICG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia; Laboratory of Mathematical Problems of Geophysics, Institute of Computational Mathematics and Mathematical Geophysics (ICM & MG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia; Chair of Informatics Systems, Faculty of Information Technologies, Novosibirsk State UniversityNovosibirsk, Russia.
authors.forename: Nikolay
authors.initials: N
authors.lastname: Podkolodnyy
authors.affiliation: Laboratory of Analysis and Optimization of Non-Linear Systems, Institute of Computational Technologies (ICG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia; Chair of Mathematical Modeling, Faculty of Mechanics and Mathematics, Novosibirsk State UniversityNovosibirsk, Russia.
authors.forename: Sergey
authors.initials: S
authors.lastname: Golushko
authors.affiliation: Department of Systems Biology, Institute of Cytology and Genetics (ICG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia; Chair of Informational Biology, Faculty of Natural Sciences, Novosibirsk State UniversityNovosibirsk, Russia.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Afonnikov
authors.affiliation: Department of Systems Biology, Institute of Cytology and Genetics (ICG), Siberian Branch of Russian Academy of ScienceNovosibirsk, Russia; Chair of Informational Biology, Faculty of Natural Sciences, Novosibirsk State UniversityNovosibirsk, Russia.
authors.forename: Nikolay
authors.initials: N
authors.lastname: Kolchanov
keywords: autonomous cell growth; cell mechanics; cell-based models; osmotic and turgor pressure; symplastic growth; wheat leaf epidermis