title: Microcirculation violations of the conjunctiva in clean up workers of the Chornobyl NPP accident.
abstract: OBJECTIVE
  Explore hemomicrocirculation changes after radiation exposure depending of irradiation dose in dynam ics.
  
  
  METHODS
  The research conducted on 470 clean up workers of the Chornobyl NPP accident. After 10-15 years after radiation exposure examined 450 Chornobyl clean up workers in age of 28 to 65 years. The con trol group consisted of 110 industrial workers who had not a contact of IR. In 22 years after radiation exposure sep arately examined 20 randomly selected Chornobyl clean up workers accident. The microcirculation state examine by the vessels biomicroscopy of the bulbar conjunctiva. The statistical analysis of the results of the study included the determination of the t coefficient (Student's), correlation coefficient and its error.
  
  
  RESULTS
  The research of the state of microcirculation in the conjunctiva revealed the presence of significant irreg ularities in exposure persons in the period of 10-15 years after radiation exposure. The dependence educed of the degree and frequency of pathology of the microvessels of dose accumulation. In 22 years after radiation exposure hemomicrocirculation violations remained widespread, a large proportion was vascular and perivascular changes. Established that the dose dependences for changes of the microcirculation in the remote period in participants work at Chornobyl in 1986 save.
  
  
  CONCLUSIONS
  It is shown that the appearance of the significant violations of microcirculation state in the conjunc tiva observed in exposed persons in the period from 10 to 15 years after radiation exposure. In 22 years after radi ation exposure dose dependence hemomicrocirculation violations remained widespread, and clinical features are preserved.
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, 53 Melnykova Street, Kyiv, 04050, Ukraine.
authors.forename: P A
authors.initials: PA
authors.lastname: Fedirko
authors.affiliation: State Institution Dnipropetrovsk Medical Academy of the Ministry of health of Ukraine, Vernadskoho str., 9, Dnipro, 49044, Ukraine.
authors.forename: N A
authors.initials: NA
authors.lastname: Garkava
mesh_terms: D000328:Adult; D000368:Aged; D047852:Chernobyl Nuclear Accident; D003228:Conjunctiva / Q000098:blood supply*; D006801:Humans; D008833:Microcirculation; D008875:Middle Aged; D016273:Occupational Exposure; D011829:Radiation Dosage
keywords: Chornobyl accident; conjunctiva; ionizing radiation; microcirculation