title: NanoGenotoxicology: present and the future.
abstract: This Mutagenesis special issue is on the topic of nanogenotoxicology. It unites a collection of reports that provide insight into: (i) the properties of engineered nanomaterials (ENMs) that contribute to genotoxicity, (ii) the genotoxic mechanisms associated with DNA damage observed in both in vitro and in vivo tests and (iii) the future test systems that will provide more accurate prediction of ENM genotoxicity to support regulatory hazard assessment frameworks. The contributions within therefore provide collective oversight of our current understanding, coupled to future perspectives aimed at overcoming technical hurdles and describing novel analytical methods to further advance the field.
authors.affiliation: In Vitro Toxicology Group, Institute of Life Science and Centre for NanoHealth, Swansea Univeristy Medical School, Swansea University, Singleton Park, Swansea SA2 8PP, Wales, UK and.
authors.forename: Shareen H
authors.initials: SH
authors.lastname: Doak
authors.affiliation: Health Effects Group, Department of Environmental Chemistry, NILU- Norwegian Institute for Air Research, N-2027 Kjeller, Norway maria.dusinska@nilu.no.
authors.forename: Maria
authors.initials: M
authors.lastname: Dusinska
mesh_terms: D000818:Animals; D004247:DNA / Q000187:drug effects*; D004249:DNA Damage; D006801:Humans; D009152:Mutagenicity Tests / Q000639:trends; D049329:Nanostructures / Q000633:toxicity*
chemical_list: D004247:DNA