title: Gaining Synthetic Appreciation for the Gedunin ABC Ring System.
abstract: Gedunin, first isolated in 1960, displays a remarkable range of biological activity, but has yet to receive dedicated synthetic attention from a ground up construction perspective. Presented herein is a successfully executed approach to the fully functionalized ABC ring system of this challengingly complex natural product.
authors.affiliation: School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, 4072, Queensland, Australia.
authors.forename: David M
authors.initials: DM
authors.lastname: Pinkerton
authors.affiliation: School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, 4072, Queensland, Australia.
authors.forename: Timothy J
authors.identifier: http://orcid.org/0000-0001-8941-8670
authors.initials: TJ
authors.lastname: Vanden Berg
authors.affiliation: School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, 4072, Queensland, Australia.
authors.forename: Paul V
authors.initials: PV
authors.lastname: Bernhardt
authors.affiliation: School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, 4072, Queensland, Australia.
authors.forename: Craig M
authors.identifier: http://orcid.org/0000-0002-3834-7398
authors.initials: CM
authors.lastname: Williams
keywords: Hsp90; epoxidation; gedunin; hydrogenation; limonoid