title: Adherence to Antituberculosis Drugs in Children and Adolescents in A Low-Endemic Setting: A Retrospective Series.
abstract: Adherence to antituberculosis drug regimens is critical for the prevention and treatment of tuberculosis in pediatrics. In a large retrospective series of children and adolescents in Barcelona, Spain, completion of treatment was worse among patients treated for latent infection, compared with those treated for active tuberculosis or receiving primary chemoprophylaxis. Toxicity and cultural and language barriers were identified as predictors of nonadherence.
authors.affiliation: From the *Faculty of Medicine and Health Sciences, Department of Medical and Surgical Nursing, Universitat de Barcelona; Barcelona, Spain; †Pediatric Tuberculosis Unit, Nursing Department and Hospital Sant Joan de Déu-Universitat de Barcelona, Barcelona, Spain; ‡Malalties infeccioses i resposta inflamatòria sistèmica en pediatria, Unitat d´Infeccions, Servei de Pediatria, Institut de Recerca Pediàtrica Hospital Sant Joan de Déu, Barcelona, Spain; §Departament de Pediatria, Universitat de Barcelona, Barcelona, Spain; and ¶CIBER de Epidemiología y Salud Pública, Ciberesp, Spain.
authors.forename: Eva-Maria
authors.initials: EM
authors.lastname: Guix-Comellas
authors.forename: Librada
authors.initials: L
authors.lastname: Rozas
authors.forename: Eneritz
authors.initials: E
authors.lastname: Velasco-Arnaiz
authors.forename: Victoria
authors.initials: V
authors.lastname: Morín-Fraile
authors.forename: Enriqueta
authors.initials: E
authors.lastname: Force-Sanmartín
authors.forename: Antoni
authors.initials: A
authors.lastname: Noguera-Julian
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D014376:Tuberculosis / Q000188:drug therapy* / Q000453:epidemiology; D016903:Drug Monitoring
chemical_list: D000995:Antitubercular Agents