title: Impact of Examined Lymph Node Count on Precise Staging and Long-Term Survival of Resected Non-Small-Cell Lung Cancer: A Population Study of the US SEER Database and a Chinese Multi-Institutional Registry.
abstract: Purpose We investigated the correlation between the number of examined lymph nodes (ELNs) and correct staging and long-term survival in non-small-cell lung cancer (NSCLC) by using large databases and determined the minimal threshold for the ELN count. Methods Data from a Chinese multi-institutional registry and the US SEER database on stage I to IIIA resected NSCLC (2001 to 2008) were analyzed for the relationship between the ELN count and stage migration and overall survival (OS) by using multivariable models. The series of the mean positive LNs, odds ratios (ORs), and hazard ratios (HRs) were fitted with a LOWESS smoother, and the structural break points were determined by Chow test. The selected cut point was validated with the SEER 2009 cohort. Results Although the distribution of ELN count differed between the Chinese registry (n = 5,706) and the SEER database (n = 38,806; median, 15 versus seven, respectively), both cohorts exhibited significantly proportional increases from N0 to N1 and N2 disease (SEER OR, 1.038; China OR, 1.012; both P < .001) and serial improvements in OS (N0 disease: SEER HR, 0.986; China HR, 0.981; both P < .001; N1 and N2 disease: SEER HR, 0.989; China HR, 0.984; both P < .001) as the ELN count increased after controlling for confounders. Cut point analysis showed a threshold ELN count of 16 in patients with declared node-negative disease, which were examined in the derivation cohorts (SEER 2001 to 2008 HR, 0.830; China HR, 0.738) and validated in the SEER 2009 cohort (HR, 0.837). Conclusion A greater number of ELNs is associated with more-accurate node staging and better long-term survival of resected NSCLC. We recommend 16 ELNs as the cut point for evaluating the quality of LN examination or prognostic stratification postoperatively for patients with declared node-negative disease.
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Liang
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Jiaxi
authors.initials: J
authors.lastname: He
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Yaxing
authors.initials: Y
authors.lastname: Shen
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Jianfei
authors.initials: J
authors.lastname: Shen
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Qihua
authors.initials: Q
authors.lastname: He
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Jianrong
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Gening
authors.initials: G
authors.lastname: Jiang
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Qun
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Lunxu
authors.initials: L
authors.lastname: Liu
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Shugeng
authors.initials: S
authors.lastname: Gao
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Deruo
authors.initials: D
authors.lastname: Liu
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Calvin S H
authors.initials: CS
authors.lastname: Ng
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Chia-Chuan
authors.initials: CC
authors.lastname: Liu
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: René Horsleben
authors.initials: RH
authors.lastname: Petersen
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Gaetano
authors.initials: G
authors.lastname: Rocco
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Thomas
authors.initials: T
authors.lastname: D'Amico
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Brunelli
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Haiquan
authors.initials: H
authors.lastname: Chen
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Xiuyi
authors.initials: X
authors.lastname: Zhi
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Yixin
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Wensen
authors.initials: W
authors.lastname: Chen
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, The First Affiliated Hospital of Guangzhou Medical University; Wenhua Liang, Jiaxi He, Jianfei Shen, Qihua He, Jianrong Zhang, and Jianxing He, Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease; Zhihua Zhu, Cancer Center of Sun Yat-Sen University; Qian Zhou, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou; Jianfei Shen, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai; Yaxing Shen and Qun Wang, Shanghai Zhongshan Hospital of Fudan University; Gening Jiang, Shanghai Pulmonary Hospital of Tongji University; Haiquan Chen, Fudan University Shanghai Cancer Center, Shanghai; Lunxu Liu, West China Hospital, Sichuan University, Chengdu; Shugeng Gao, Cancer Institute & Hospital, Chinese Academy of Medical Sciences; Shugeng Gao, Peking Union Medical College; Shugeng Gao, National Cancer Center; Deruo Liu, China and Japan Friendship Hospital; Xiuyi Zhi, Beijing Xuanwu Hospital of Capital Medical University; Bo Liu and Yixin Yang, Academy of Mathematics and Systems Science in the Chinese Academy of Sciences, Beijing; Zheng Wang, Shenzhen People's Hospital, Shenzhen; Calvin S.H. Ng, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region; Wensen Chen, Nanjing Medical University; Wensen Chen, the First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China; Chia-chuan Liu, Sun Yat-Sen Cancer Center, Taipei, Republic of China; René Horsleben Petersen, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark; Gaetano Rocco, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy; Thomas D'Amico, Duke University Medical Center, Durham, NC; and Alessandro Brunelli, St James's University Hospital, Leeds, United Kingdom.
authors.forename: Jianxing
authors.initials: J
authors.lastname: He
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D002681:China; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012044:Regression Analysis; D012189:Retrospective Studies; D018426:SEER Program; D015996:Survival Rate; D013997:Time Factors; D014481:United States