title: Haematopoietic stem cells show their true colours.
abstract: Delineating the behaviour of haematopoietic stem cells (HSCs) in vivo has thus far proven challenging. Two studies in zebrafish and mouse models now track HSCs in vivo using fate mapping with multicolour approaches to provide further insights into clonal events that regulate blood development, HSC function and differentiation during homeostasis and stress conditions.
authors.affiliation: Beth Israel Deaconess Medical Center, Department of Pathology, Harvard Medical School, Harvard Stem Cell Institute, CLS 536, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.
authors.forename: Trista E
authors.initials: TE
authors.lastname: North
authors.affiliation: Brigham and Women's Hospital, Genetics and Gastroenterology Division, Harvard Medical School, Harvard Stem Cell Institute, NRB 458, 77 Avenue Louis Pasteur, Boston, Massachusetts 02215, USA.
authors.forename: Wolfram
authors.initials: W
authors.lastname: Goessling
mesh_terms: D000818:Animals; D058948:Cell Tracking; D002999:Clone Cells; D004625:Embryo, Nonmammalian / Q000166:cytology; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006706:Homeostasis; D051379:Mice; D013312:Stress, Physiological; D015027:Zebrafish / Q000196:embryology