title: Assessment of binding properties of Actinomycin-D to 21nt DNA segment of hmgb1 gene promoter using spectroscopic and calorimetric techniques.
authors.affiliation: a Department of Biochemistry , All India Institute of Medical Sciences , New Delhi , India.
authors.forename: Neelam
authors.initials: N
authors.lastname: Lohani
authors.affiliation: a Department of Biochemistry , All India Institute of Medical Sciences , New Delhi , India.
authors.forename: Himanshu Narayan
authors.initials: HN
authors.lastname: Singh
authors.affiliation: a Department of Biochemistry , All India Institute of Medical Sciences , New Delhi , India.
authors.forename: Moganty R
authors.initials: MR
authors.lastname: Rajeswari
mesh_terms: D001665:Binding Sites; D002151:Calorimetry; D004247:DNA / Q000737:chemistry; D003609:Dactinomycin / Q000737:chemistry* / Q000627:therapeutic use; D024243:HMGB1 Protein / Q000037:antagonists & inhibitors / Q000737:chemistry*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D009690:Nucleic Acid Conformation / Q000187:drug effects; D011401:Promoter Regions, Genetic / Q000187:drug effects; D011485:Protein Binding / Q000187:drug effects*; D013057:Spectrum Analysis
chemical_list: D024243:HMGB1 Protein; C585491:HMGB1 protein, human; D003609:Dactinomycin; D004247:DNA
keywords: Act-D; HMGB1; calorimeter; drug–DNA interaction; minor groove binders; spectroscopy