title: Hemodynamics of His Bundle pacing.
abstract: This review will focus on the feasibility of long term His bundle pacing and its effects on left ventricle (LV) hemodynamics. Compared with right ventricular pacing, His bundle pacing results in a more physiological electro-mechanical activation that contributes to preserve LV function. Moreover some studies showed a similar effect to biventricular pacing in patients with heart failure and left bundle branch block. Recent observations indicate that His bundle pacing should be considered as an optimal site to pace right ventricle in patients who are candidates for cardiac resynchronization therapy.
authors.affiliation: Heart Failure and Electrophysiology Unit, IRCCS MultiMedica, Milano. Electronic address: lucap.alberti@gmail.com.
authors.forename: Luca
authors.initials: L
authors.lastname: Alberti
authors.affiliation: Arrhythmology Unit, Careggi University Hospital, Florence.
authors.forename: Paolo
authors.initials: P
authors.lastname: Pieragnoli
authors.affiliation: Arrhythmology Unit, Careggi University Hospital, Florence.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ricciardi
authors.affiliation: Heart Failure and Electrophysiology Unit, IRCCS MultiMedica, Milano; Arrhythmology Unit, Careggi University Hospital, Florence; Chair of Cardiology, University of Florence.
authors.forename: Luigi
authors.initials: L
authors.lastname: Padeletti
mesh_terms: D002036:Bundle of His / Q000503:physiopathology*; D002037:Bundle-Branch Block / Q000150:complications / Q000503:physiopathology* / Q000628:therapy*; D002304:Cardiac Pacing, Artificial / Q000009:adverse effects / Q000379:methods*; D003326:Coronary Circulation; D019317:Evidence-Based Medicine; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000209:etiology / Q000503:physiopathology*