title: Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Combination Treatment in Patients with HIV/HCV Co-Infection: Results of an Italian Compassionate Use Program.
abstract: Patients co-infected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are at high risk of liver disease progression. We report a favorable safety profile and SVR12 rates of 96.7% among HIV/HCV co-infected patients participating in an Italian compassionate-use program of ombitasvir/paritaprevir/ritonavir + dasabuvir (OBV/PTV/r + DSV) ± ribavirin (RBV).
authors.affiliation: Clinical Infectious Diseases, Department. of Systems Medicine, Tor Vergata University, Rome, Italy.
authors.forename: Andreoni
authors.initials: A
authors.lastname: Massimo
authors.affiliation: Clinical Infectious Diseases, Department. of Systems Medicine, Tor Vergata University, Rome, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Teti
authors.affiliation: Clinical Department, National Institute for Infectious Diseases, INMI "L. Spallanzani″, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Antinori
authors.affiliation: Department of Biomedical and Clinical Science, University of Milan,Milan, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Milazzoi
authors.affiliation: Department of Biomedical and Clinical Science, University of Milan,Milan, Italy.
authors.forename: Savatore
authors.initials: S
authors.lastname: Sollima
authors.affiliation: Department of Infectious Diseases, ASST Fatebenefratelli Sacco, Milan, Italy, and School of Clinical Medicine, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: Giuliano
authors.initials: G
authors.lastname: Rizzardini
authors.affiliation: Infectious Disease Clinic, IRCCS University Hospital, San Martino IST, Genova, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Di Biagio
authors.affiliation: Institute of Infectious Disease, University of Bari, Bari, Italy.
authors.forename: Annalisa
authors.initials: A
authors.lastname: Saracino
authors.affiliation: Division of Infectious and Tropical Diseases, IRCCS Policlinico San Matteo, Pavia, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Bruno
authors.affiliation: Infectious Diseases Clinic, University Hospital, Modena, Italy.
authors.forename: Vanni
authors.initials: V
authors.lastname: Borghi
authors.affiliation: Department of Internal and Specialty Medicine University Infectious Diseases Unit, AOU Senese, Siena, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: De Luca
authors.affiliation: Department of Infectious and Tropical Diseases, University Hospital, Padova, Italy.
authors.forename: Annamaria
authors.initials: A
authors.lastname: Cattelan
authors.affiliation: Department of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Hamid
authors.initials: H
authors.lastname: Hasson
authors.affiliation: Department of Clinical Medicine, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
authors.forename: Gloria
authors.initials: G
authors.lastname: Taliani
authors.affiliation: Clinic of Infectious and Tropical Diseases, Department of Health Sciences, University of Milan, Milan, Italy.
authors.forename: Antonella D'Arminio
authors.initials: AD
authors.lastname: Monforte
authors.affiliation: Infectious Diseases Unit, Sapienza University of Rome, Latina, Italy, and Department of Public Health and Infectious Diseases, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
authors.forename: Claudio Maria
authors.initials: CM
authors.lastname: Mastroianni
authors.affiliation: Unit of Infectious Diseases, University of Turin, Department of Medical Sciences, "Amedeo di Savoia″ Hospital, Turin, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Di Perri
authors.affiliation: Division of Infectious Diseases, AO Papa Giovanni XXIII, Bergamo, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Bigoni
authors.affiliation: Division of Infectious Diseases, AO Niguarda Ca' Granda Hospital, Milan, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Puoti
authors.affiliation: Division of Infectious and Tropical Diseases, University of Brescia and Spedali Civili General Hospital, Brescia, Italy.
authors.forename: Angiola
authors.initials: A
authors.lastname: Spinetti
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, "San Gerardo″ Hospital, University of Milan-Bicocca, Milan, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Gori
authors.affiliation: First Division of Infectious Diseases, S. Giovanni di Dio e Ruggi d'Aragona Hospital, Salerno, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Boffa
authors.affiliation: Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.
authors.forename: Cacopardo
authors.initials: C
authors.lastname: Bruno
authors.affiliation: Infectious Diseases Unit, Department of Biomedical Sciences and Public Health, Marche Polytechnic University c/o Ospedali Riuniti, Ancona, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Giacometti
authors.affiliation: Infectious Disease Unit, Pescara General Hospital, Pescara, Italy.
authors.forename: Giustino
authors.initials: G
authors.lastname: Parruti
authors.affiliation: Department of Public Health and Infectious Diseases, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Vullo
authors.affiliation: III U.O.C. P.O. Cotugno, AORN Ospedali dei Colli, Naples, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Chirianni
authors.affiliation: Clinical Infectious Diseases, Sant'Andrea Hospital - Sapienza University of Rome, Rome, Italy.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Pennica
authors.affiliation: Clinical Infectious Diseases, Sant'Andrea Hospital - Sapienza University of Rome, Rome, Italy.
authors.forename: Caterina
authors.initials: C
authors.lastname: Pasquazzi
authors.affiliation: Unit of Infectious Diseases, University Hospital of Ferrara, Ferrara, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Segala
authors.affiliation: Clinical Infectious Diseases, Department. of Systems Medicine, Tor Vergata University, Rome, Italy.
authors.forename: Loredana
authors.initials: L
authors.lastname: Sarmati
keywords: DAA; HIV/HCV co-infection; IFN-free; anti-HCV therapy; antiviral therapy