title: Systematic review of childhood and adolescent risk and prognostic factors for persistent abdominal pain.
abstract: This review aimed to identify childhood and adolescence risk and prognostic factors associated with onset and persistence of persistent abdominal pain and related disability and assess quality of the evidence. While findings suggest a possible role for negative emotional symptoms and parental mental health as risk and prognostic factors for onset and persistence of persistent abdominal pain, the evidence is of poor quality overall and nonexistent when it comes to prognostic factors associated with disability.
  
  
  CONCLUSIONS
  Further research is needed to increase confidence in existing evidence and to explore new factors. This research will inform prevention.
authors.affiliation: IWK Health Centre, Halifax, NS, Canada.|Department of Community Health and Epidemiology, Dalhousie University, Halifax, NS, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Huguet
authors.affiliation: Department of Psychology, University of New Brunswick, Federicton, NB, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Olthuis
authors.affiliation: IWK Health Centre, Halifax, NS, Canada.|Department of Community Health and Epidemiology, Dalhousie University, Halifax, NS, Canada.|Departments of Pediatrics and Psychiatry, Dalhousie University, Halifax, NS, Canada.
authors.forename: P J
authors.initials: PJ
authors.lastname: McGrath
authors.affiliation: Department of Psychology & Neuroscience, Dalhousie University, Halifax, NS, Canada.
authors.forename: M E
authors.initials: ME
authors.lastname: Tougas
authors.affiliation: Department of Community Health and Epidemiology, Dalhousie University, Halifax, NS, Canada.
authors.forename: J A
authors.initials: JA
authors.lastname: Hayden
authors.affiliation: Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada.
authors.forename: J N
authors.initials: JN
authors.lastname: Stinson
authors.affiliation: IWK Health Centre, Halifax, NS, Canada.|Departments of Pediatrics and Psychiatry, Dalhousie University, Halifax, NS, Canada.|Department of Psychology & Neuroscience, Dalhousie University, Halifax, NS, Canada.
authors.forename: C T
authors.initials: CT
authors.lastname: Chambers
mesh_terms: D015746:Abdominal Pain / Q000453:epidemiology*; D000293:Adolescent; D002648:Child; D006801:Humans; D012307:Risk Factors
keywords: Adolescent; Children; Persistent abdominal pain; Prognostic factors; Risk factors