title: [Progress of Experimental Research on Differentiation of Muscle-Derived Stem Cells into Haematopoietic Lineages in Vitro -Review].
abstract: Muscle-derived stem cells (MDSC) are a population of multipotent stem cells in the muscular tissue. It provide an excellent prospect of hemopathy treatment due to their superiorities, such as rich sources, convenient material resource and a high survival rate after transplantation and so on. However, there are great differences in sampling, separation, purification, and proliferation when MDSC were cultured in vitro. In addition, the proliferation conditions of the MDSC in vitro are yet unclear. The related regulatory mechanisms, which MDSC transformed into haematopoietic cells, need to be investigated. In this article, the experimental researches on the differentiation of MDSC into haematopoietic lineages are reviewed, the concrete problems discussed in this review are culture of MDSC in vitro, identification of MDSC, proleferation of MDSC, differention of MDSC in to hematopoietic lineages and so on.
authors.affiliation: School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
authors.forename: Juan-Juan
authors.initials: JJ
authors.lastname: Wang
authors.affiliation: School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
authors.forename: Xiao-Ning
authors.initials: XN
authors.lastname: Gao
authors.affiliation: School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
authors.forename: Shan-Shan
authors.initials: SS
authors.lastname: Chen
authors.affiliation: School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
authors.forename: Pan-Pan
authors.initials: PP
authors.lastname: Zhang
authors.affiliation: School of Integrated Traditional Chinese and Western Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. E-mail: wangtao6112@163.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.affiliation: School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. E-mail: douhaoying11@126.com.
authors.forename: Hao-Ying
authors.initials: HY
authors.lastname: Dou
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D019070:Cell Lineage; D006413:Hematopoietic System; D039902:Multipotent Stem Cells; D018482:Muscle, Skeletal