title: Takotsubo Cardiomyopathy Associated with Primary Hyperthyroidism Secondary to Toxic Multinodular Goiter.
abstract: Takotsubo cardiomyopathy is increasingly recognized as a distinct clinical entity. An association with thyroid disease has been identified in several case reports, mostly in the context of Grave disease. We report the case of a 67-year-old woman presenting with takotsubo cardiomyopathy and thyrotoxicosis secondary to toxic multinodular goiter. Previously unreported, this suggests that this association is related to the direct effects of thyroid hormone, rather than an autoimmune mechanism. Thyroid disease should be considered in patients presenting with takotsubo cardiomyopathy.
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, Brisbane, Australia; School of Medicine, The University of Queensland, Brisbane, Australia.
authors.forename: Dale
authors.initials: D
authors.lastname: Murdoch
authors.affiliation: Department of Endocrinology, Gold Coast University Hospital, Gold Coast, Australia.
authors.forename: William
authors.initials: W
authors.lastname: O'Callaghan
authors.affiliation: Department of Endocrinology, Gold Coast University Hospital, Gold Coast, Australia.
authors.forename: Elham
authors.initials: E
authors.lastname: Reda
authors.affiliation: Department of Endocrinology, Gold Coast University Hospital, Gold Coast, Australia; School of Medicine, Griffith University, Gold Coast, Australia.
authors.forename: Selvanayagam
authors.initials: S
authors.lastname: Niranjan
keywords: cardiomyopathy; hyperthyroidism; takotsubo; toxic multinodular goiter