title: Hysterosalpingo-Contrast Sonography With Four-Dimensional Technique for Screening Fallopian Tubal Patency: Let's Make an Exploration.
abstract: To evaluate the practicability of transvaginal 4-dimensional (4D) hysterosalpingo-contrast sonography (HyCoSy) using SonoVue for screening of fallopian tube patency in infertile females.
  
  
  
  Prospective observational study (Canadian Task Force classification II-2).
  
  
  
  The Second Affiliated Hospital of Zhejiang University.
  
  
  
  204 infertile females who underwent 4D-HyCoSy between July 2015 and June 2016.
  
  
  
  4D-HyCoSy was performed to acquire dynamic images. If any of the fallopian tubes was not developing during the process, the procedure was repeated promptly, to exclude false-positive outcomes. Subsequently, tube status was confirmed by traditional 2-dimensional (2D)-HyCoSy. Finally, the results of the 4D-HyCoSy and the final 2D-HyCoSy were compared.
  
  
  
  A total of 204 patients (408 tubes) were evaluated ith 4D-HyCoSy followed by 2D-HyCoSy. Of these 408 tubes, 385 demonstrated the same status on 4D-HyCoSy and 2D-HyCoSy, for an agreement rate of 94.4%.
  
  
  
  A 4D technique combined with HyCoSy is a practicable screening method for assessing fallopian tube patency. It overcomes the disadvantages of 2D-HyCoSy and has a relatively high degree of agreement with the more difficult 2D-HyCoSy technique.
authors.affiliation: Department of Ultrasonography, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
authors.forename: Fenhong
authors.initials: F
authors.lastname: Chen
authors.affiliation: Department of Ultrasonography, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Quan
authors.affiliation: Department of Ultrasonography, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
authors.forename: Pintong
authors.initials: P
authors.lastname: Huang
authors.affiliation: Department of Ultrasonography, Second Affiliated Hospital of Zhejiang University, Hangzhou, China. Electronic address: xdyou@sina.com.
authors.forename: Xiangdong
authors.initials: X
authors.lastname: You
mesh_terms: D000328:Adult; D003287:Contrast Media; D005184:Fallopian Tube Diseases / Q000000981:diagnostic imaging*; D005186:Fallopian Tube Patency Tests / Q000379:methods*; D005187:Fallopian Tubes / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007247:Infertility, Female / Q000000981:diagnostic imaging*; D010743:Phospholipids; D011446:Prospective Studies; D013459:Sulfur Hexafluoride; D014463:Ultrasonography / Q000379:methods
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride
keywords: Fallopian tube patency; Four-dimensional; Infertility; SonoVue; Sonography