title: Cross-Sectional Study Evaluating Skin, Hair, Nail, and Bone Disease in Patients with Focal Dermal Hypoplasia.
abstract: Focal dermal hypoplasia (FDH) is an X-linked dominant disease characterized by dermal thinning and fat herniation with other ectodermal and mesodermal abnormalities. There is limited literature regarding the symptomatology and progression of skin, hair, and nail disease. The risk of bone fragility has not been explored either. This cross-sectional survey-based study explored these gaps in knowledge and provides direction for future avenues of research in FDH.
authors.affiliation: Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts.|Harvard Medical School, Boston, Massachusetts.
authors.forename: Nicole S
authors.initials: NS
authors.lastname: Gunasekera
authors.affiliation: Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts.
authors.forename: Joan K
authors.initials: JK
authors.lastname: Divito
authors.affiliation: Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts.|Harvard Medical School, Boston, Massachusetts.
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Kupper
authors.affiliation: Harvard Medical School, Boston, Massachusetts.|Dermatology Program, Division of Immunology, Boston Children's Hospital, Boston, Massachusetts.
authors.forename: Jennifer T
authors.initials: JT
authors.lastname: Huang
authors.affiliation: Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts.|Harvard Medical School, Boston, Massachusetts.
authors.forename: Sherrie J
authors.initials: SJ
authors.lastname: Divito
mesh_terms: D000293:Adolescent; D001847:Bone Diseases / Q000150:complications* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005489:Focal Dermal Hypoplasia / Q000150:complications* / Q000473:pathology*; D006197:Hair; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009262:Nails; D012867:Skin