title: Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review.
abstract: Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical presentation that can be quite bizarre, mandating a long list of differential diagnostic possibilities, and subsequent rise of a puzzling diagnostic challenge. We describe an ESRD patient who presented with blistering, nonhealing ulcerative lesions with a diagnostic skin biopsy revealing a mixed pattern of linear IgA bullous dermatosis and dermatitis herpetiformis. A clinical remission could be achieved with pulse intravenous steroids followed by oral maintenance in combination with dapsone, with no evidence of recurrence.
authors.affiliation: Division of Nephrology and Hypertension, Department of Internal Medicine, Wayne State University Detroit Medical Center, Detroit, MI, USA.
authors.forename: Zeenat Yousuf
authors.identifier: 0000-0003-1960-1730
authors.initials: ZY
authors.lastname: Bhat
authors.affiliation: Division of Nephrology and Hypertension, Department of Internal Medicine, Wayne State University Detroit Medical Center, Detroit, MI, USA.
authors.forename: Marwan
authors.initials: M
authors.lastname: Abu Minshar
authors.affiliation: Division of Nephrology and Hypertension, Department of Internal Medicine, Wayne State University Detroit Medical Center, Detroit, MI, USA.
authors.forename: Nashat
authors.identifier: 0000-0002-5772-2659
authors.initials: N
authors.lastname: Imran
authors.affiliation: Department of Pathology, Wayne State University Detroit Medical Center, Detroit, MI, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Thompson
authors.affiliation: Division of Nephrology and Hypertension, Department of Internal Medicine, Wayne State University Detroit Medical Center, Detroit, MI, USA.
authors.forename: Yahya Osman
authors.initials: YO
authors.lastname: Malik