title: Sclerosing angiomatoid nodular transformation of the spleen presenting rapid growth after adrenalectomy: Report of a case.
abstract: BACKGROUND
  Sclerosing angiomatoid nodular transformation (SANT) is a rare benign lesion with an unknown natural history and pathogenesis. So far fewer than 100 cases were documented, but detailed incidence and prevalence are unknown.
  
  
  METHODS
  We report a case of SANT of the spleen in a 37-year-old man that showed rapid growth after adrenalectomy for primary aldosteronism. Computed tomography showed a nodule in the spleen that increased in size from 2.0cm to 7.0cm during 3 years of observation.
  
  
  CONCLUSIONS
  This case is reported because data regarding growth rates and natural history of these lesions are limited and few cases have been reported to show the rapid growth progression seen in this case.
  
  
  CONCLUSIONS
  Decreases in glucocorticoid concentrations following adrenalectomy may have contributed to the rapid growth of SANT of the spleen, because SANT is considered to be related to immunoglobulin G4-associated disease.
authors.affiliation: Department of Gastroenterological Surgery, Hiroshima City Hiroshima Citizens Hospital, 7-33 Motomachi, Naka-ku, Hiroshima, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Nagai
authors.affiliation: Department of Gastroenterological Surgery, Hiroshima City Hiroshima Citizens Hospital, 7-33 Motomachi, Naka-ku, Hiroshima, Japan. Electronic address: ddds4863@gmail.com.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Satoh
authors.affiliation: Department of Gastroenterological Surgery, Hiroshima City Hiroshima Citizens Hospital, 7-33 Motomachi, Naka-ku, Hiroshima, Japan.
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Matsukawa
authors.affiliation: Department of Gastroenterological Surgery, Hiroshima City Hiroshima Citizens Hospital, 7-33 Motomachi, Naka-ku, Hiroshima, Japan.
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Shiozaki
keywords: Adrenalectomy; Glucocorticoid; Hand assisted laparoscopic surgery; IgG4-associated disease; Sclerosing angiomatoid nodular transformation (SANT)