title: Marine actinobacteria as a drug treasure house.
abstract: Marine actinobacteria have been considered as a gold mine with respect to great potential regarding their secondary metabolites. Most of the researches have been conducted on actinobacteria's derived secondary metabolites to examine its pharmacological properties. Actinobacteria have a potential to provide future drugs against crucial diseases, such as drug-resistance bacteria, cancer, a range of viral illnesses, malaria, several infections and inflammations. Although, the mode of action of many bio molecules are still untapped, for a tangible number of compounds by which they interfere with human pathogenesis are reported here with detailed diagrammed illustrations. This knowledge is one of the basic vehicles to be known especially for transforming bio medicinal molecules to medicines. Actinobacteria produce a different kind of biochemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. Different diseases have the capability to fight at different sites inside the body can lead to a new wave of increasing the chances to produce targeted medicines.
authors.affiliation: Ocean College, Zhejiang University, Hangzhou 310058, China. Electronic address: hassan13@zju.edu.cn.
authors.forename: Syed Shams Ul
authors.initials: SSU
authors.lastname: Hassan
authors.affiliation: School of Medicine, Zhejiang University, Hangzhou 310058, China.
authors.forename: Abdul Lateef
authors.initials: AL
authors.lastname: Shaikh
mesh_terms: D039903:Actinobacteria / Q000502:physiology*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D001688:Biological Products / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D055808:Drug Discovery / Q000639:trends*; D006801:Humans; D040141:Staphylococcaceae / Q000187:drug effects / Q000502:physiology
chemical_list: D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D001688:Biological Products
keywords: Anti-inflammatory activity; Anticancer activity; Bio medicinal molecules; Chemical structures; Marine actinobacteria; Medicines