title: Sleep quality improves with endoscopic sinus surgery in patients with chronic rhinosinusitis and nasal polyposis.
abstract: BACKGROUND
  Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP) is a chronic disease that has a major impact on generic and disease-specific quality of life. Little is known about the influence of CRSwNP on sleep and what effect surgery for CRSwNP has on sleep quality. The aim of the study was to investigate sleep quality in patients with CRSwNP before and after endoscopic surgery.
  
  
  METHODS
  Forty-two patients filled out four validated sleep questionnaires and one sino/nasal, disease specific quality of life questionnaire before surgery and three months later. A healthy control group filled out the same questionnaires at baseline and after three months.
  
  
  RESULTS
  An impact on sleep patterns was found in all sleep questionnaires and surgery clearly improved the quality of sleep. The Sino-nasal outcome test sum score decreased from median 51,5 to 26,5. Epworth sleepiness scale showed a decline in score from score 7.5 to 6.0. Surgery also reduced the risk for obstructive sleep apnoea in 13 patients evaluated by the Berlin Questionnaire and Multivariable Apnea Prediction Index.
  
  
  CONCLUSIONS
  Patients with CRSwNP had impaired sleep quality, daytime sleepiness, nasal patency, and risk for sleep apnea, all of which improved after corrective surgery.
authors.affiliation: Department of Otorhinolaryngology, Skane University Hospital and Lund University, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Värendh
authors.affiliation: Occupational Therapy and Occupational Science, Lund University, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Johannisson
authors.affiliation: Department of Otorhinolaryngology, Akershus University Hospital, Lorenskog, Norway.
authors.forename: H
authors.initials: H
authors.lastname: Hrubos-Strøm
authors.affiliation: Department of Otorhinolaryngology, Skane University Hospital and Lund University, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Andersson
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D011446:Prospective Studies; D011788:Quality of Life; D012220:Rhinitis / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012852:Sinusitis / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012890:Sleep; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult