title: Recent development of transcatheter closure of atrial septal defect and patent foramen ovale with occluders.
abstract: Atrial septal defect (ASD) and patent foramen ovale (PFO) are common clinical congenital heart defects. As an effective method for the treatment of ASD and PFO, transcatheter closure with occluders presents many advantages, including safety, ease of operation, minimal invasiveness, and reduced complications. This contribution reviews the various types of occluders currently used in clinical applications and under development, including non degradable occluders, partially degradable occluders, and totally degradable occluders. A number of case studies are described in detail. Comparison is made on the treatment outcomes using different occulders. Future development of transcatheter closure is discussed, in particular the use of totally degradable occluders. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 433-443, 2018.
authors.affiliation: College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
authors.forename: Baiyu
authors.initials: B
authors.lastname: Tang
authors.affiliation: College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
authors.forename: Feng
authors.initials: F
authors.lastname: Su
authors.affiliation: College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, People's Republic of China.
authors.forename: Xiangke
authors.initials: X
authors.lastname: Sun
authors.affiliation: Qingdao Children's Heart Center, Qingdao Women and Children's Hospital, Congenital Heart Dieases Research Center of Qingdao University, Qingdao, 266034, People's Republic of China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Qingdao Children's Heart Center, Qingdao Women and Children's Hospital, Congenital Heart Dieases Research Center of Qingdao University, Qingdao, 266034, People's Republic of China.
authors.forename: Quansheng
authors.initials: Q
authors.lastname: Xing
authors.affiliation: Institut Européen des Membranes, UMR CNRS 5635, Université de Montpellier, Montpellier, 34095, France.
authors.forename: Suming
authors.initials: S
authors.lastname: Li
mesh_terms: D006328:Cardiac Catheterization / Q000295:instrumentation* / Q000401:mortality*; D054085:Foramen Ovale / Q000601:surgery*; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006801:Humans
keywords: atrial septal defect; biodegradable; occluder; patent foramen ovale