title: Internal limiting membrane: The innermost retinal barrier.
abstract: Recently, peeling of internal limiting membrane (ILM) has become one of the most common and effective surgical procedures for macular disorders. The authors discuss the adverse effects of such procedures and explore the possible functions of the membrane. We also suggest a barrier function of this membrane in addition to its possible other physiological roles. Thus, apart from the well-known inner and outer retinal barriers, ILM might be the third and innermost retinal barrier. The possible evidences supporting this hypothesis are presented.
authors.affiliation: Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
authors.forename: Rohan
authors.initials: R
authors.lastname: Chawla
authors.affiliation: Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. Electronic address: koushiktripathy@gmail.com.
authors.forename: Koushik
authors.initials: K
authors.lastname: Tripathy
authors.affiliation: Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
authors.forename: Shreyas
authors.initials: S
authors.lastname: Temkar
authors.affiliation: Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
authors.forename: Vinod
authors.initials: V
authors.lastname: Kumar
mesh_terms: D001813:Blood-Retinal Barrier; D005128:Eye Diseases / Q000601:surgery*; D015316:Genetic Therapy; D006470:Hemorrhage / Q000473:pathology; D006801:Humans; D008962:Models, Theoretical; D009336:Necrosis; D012160:Retina / Q000033:anatomy & histology / Q000473:pathology* / Q000601:surgery; D012164:Retinal Diseases / Q000473:pathology; D055213:Retinal Pigment Epithelium / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology; D012173:Retinitis / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D041623:Tomography, Optical Coherence