title: Continuous blood pressure monitoring via non-invasive radial artery applanation tonometry and invasive arterial catheter demonstrates good agreement in patients undergoing colon carcinoma surgery.
abstract: OBJECTIVE
  Radial artery applanation tonometry (RAAT) has been developed and utilized for continuous arterial pressure monitoring. However, evidence is lacking to clinically verify the RAAT technology and identify appropriate patient groups before routine clinical use. This study aims to evaluate the RAAT technology by comparing systolic blood pressure (SBP), mean blood pressure (MBP) and diastolic blood pressure (DBP) values in patients undergoing colon carcinoma surgery.
  
  
  METHODS
  Blood Pressure (BP) values obtained via RAAT (TL-300, Tensys Medical Inc., San Diego, CA, USA) and conventional arterial catheterization from 30 colon carcinoma surgical patients were collected and compared via Bland-Atman method, linear regression and 4-quadrant plot concordance analysis.
  
  
  RESULTS
  For SBPs, MBPs and DBPs, means of the differences (±standard deviation; 95% limits of agreement) were -0.9 (±7.6; -15.7 to 13.9) mmHg, 3.1 (±6.5; -9.6 to 15.8) mmHg and 4.3 (±7.4; -10.3 to 18.8) mmHg, respectively. Linear regression coefficients of determination were 0.8706 for SBPs, 0.8353 for MBPs and 0.6858 for DBPs. Four-quadrant concordance correlation coefficients were 0.8740, 0.8522 and 0.7108 for SBPs, MBPs and DBPs, respectively.
  
  
  CONCLUSIONS
  A highly selected patient collective undergoing colon carcinoma surgery was studied. BP measurements obtained via the TL-300 had clinically acceptable agreement with that acquired invasively using an arterial catheter. For use in clinical routine, it is necessary to take measures for improvement regarding movement artifacts and dilution of noise. A large sample size of patients under various conditions is also needed to further evaluate the RAAT technology before clinically routine use.
authors.affiliation: Department of Clinical Engineering, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
authors.forename: Jing
authors.initials: J
authors.lastname: Sun
authors.affiliation: Department of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
authors.forename: Hanjian
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Clinical Engineering, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Department of Clinical Engineering, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
authors.forename: Bin
authors.initials: B
authors.lastname: Mao
authors.affiliation: Department of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China.
authors.forename: Shengmei
authors.initials: S
authors.lastname: Zhu
authors.affiliation: Department of Clinical Engineering, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China. casper_feng@163.com.
authors.forename: Jingyi
authors.identifier: http://orcid.org/0000-0002-6679-526X
authors.initials: J
authors.lastname: Feng
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D062186:Arterial Pressure; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods*; D002277:Carcinoma / Q000601:surgery*; D002406:Catheterization, Peripheral; D003110:Colonic Neoplasms / Q000601:surgery*; D003422:Critical Care / Q000379:methods; D013505:Digestive System Surgical Procedures; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D008991:Monitoring, Physiologic / Q000379:methods*; D017534:Radial Artery / Q000502:physiology*; D012044:Regression Analysis; D012815:Signal Processing, Computer-Assisted
keywords: Arterial catheter; Arterial pressure measurement; Blood pressure monitoring; Colon carcinoma surgery; Radial artery applanation tonometry