title: Pathogenesis of Fungal Infections in Cystic Fibrosis.
abstract: For a long time, the microbiology of cystic fibrosis has been focussed onPseudomonas aeruginosaand associated Gram-negative pathogens. An increasing body of evidence has been compiled demonstrating an important role for moulds and yeasts within this complex patient group. Whether or not fungi are active participants, spectators or transient passersby remain to be elucidated. However, functionally, they do appear to play a contributory role in pathogenesis, albeit we do not know if this is a direct or indirect effect. The following review examines some of the key evidence for the role of fungi in CF pathogenesis.
authors.affiliation: Institute of Healthcare Policy and Practice, University of West of Scotland, Paisley, UK.
authors.forename: Craig
authors.initials: C
authors.lastname: Williams
authors.affiliation: Oral Sciences Research Group, Glasgow Dental School, School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
authors.forename: Ranjith
authors.initials: R
authors.lastname: Ranjendran
authors.affiliation: Oral Sciences Research Group, Glasgow Dental School, School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
authors.forename: Gordon
authors.initials: G
authors.lastname: Ramage
keywords: Cystic fibrosis; Fungal infections; Pathogenesis; Pseudomonas aeruginosa; Review