title: Post-implant Analysis of Epidemiologic and Eating Behavior Data Related to Weight Loss Effectiveness in Obese Patients Treated with Gastric Electrical Stimulation.
abstract: To determine possible preoperative predictors for obtaining clinically meaningful weight loss with gastric electrical stimulation (GES) using the "Three-Factor Eating Questionnaire" (TFEQ) as well as epidemiological data.
  
  
  
  Ninety-seven obese participants in a prospective multicenter randomized study conducted in nine European centers were implanted laparoscopically with the abiliti® closed-loop GES system (CLGES). Five clinical variables and three preoperative TFEQ factor scores (F1-cognitive-restraint, F2-disinhibition, and F3-hunger) were analyzed in order to determine predictors of weight loss success defined as excess weight loss (EWL) > 30% and failure defined as EWL < 20% at 12 months post-surgery.
  
  
  
  The mean 12-month %EWL with CLGES was 35.1 ± 19.7%, with a success rate of 52% and a failure rate of 19%. Significant predictors of success were body mass index (BMI) < 40 kg/m2and age ≥ 50 years, increasing probability of success by 22 and 29%, respectively. A low F1-cognitive-restraint score was a significant predictor of failure (p = 0.004). The best predictive model for success included F1-cognitive-restraint, F2-disinhibition, BMI < 40, and age ≥ 50 (p = 0.002).
  
  
  
  This retrospective analysis has shown that age, preoperative BMI, and F1-cognitive-restraint and F2-disinhibition scores from a preoperatively administered TFEQ are predictive of weight loss outcomes with CLGES and may be used for patient selection.
  
  
  
  ClinicalTrials.gov Identifier: NCT01448785.
authors.affiliation: Innovation and Minimal Invasive Surgery Unit, Virgen del Rocío, Hospital Virgen del Rocio, Avda Manuel Siurot, S/N, 41010, Sevilla, Spain. isaiasalarcon@gmail.com.
authors.forename: I
authors.initials: I
authors.lastname: Alarcón Del Agua
authors.affiliation: Innovation and Minimal Invasive Surgery Unit, Virgen del Rocío, Hospital Virgen del Rocio, Avda Manuel Siurot, S/N, 41010, Sevilla, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Socas-Macias
authors.affiliation: Department of Medicine - University of Padova, Center for the Study and the Integrated Management of Obesity, Clinica Medica 3 - Padova University Hospital, Via Giustiniani 2, 35128, Padova, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Busetto
authors.affiliation: Hospital Clínico San Carlos, Calle Profesor Martín Lagos s/n, 28040, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Torres-Garcia
authors.affiliation: Innovation and Minimal Invasive Surgery Unit, Virgen del Rocío, Hospital Virgen del Rocio, Avda Manuel Siurot, S/N, 41010, Sevilla, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Barranco-Moreno
authors.affiliation: Innovation and Minimal Invasive Surgery Unit, Virgen del Rocío, Hospital Virgen del Rocio, Avda Manuel Siurot, S/N, 41010, Sevilla, Spain.
authors.forename: P P
authors.initials: PP
authors.lastname: Garcia de Luna
authors.affiliation: Innovation and Minimal Invasive Surgery Unit, Virgen del Rocío, Hospital Virgen del Rocio, Avda Manuel Siurot, S/N, 41010, Sevilla, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Morales-Conde
mesh_terms: D000328:Adult; D004558:Electric Stimulation; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000453:epidemiology / Q000628:therapy; D019736:Prostheses and Implants; D012189:Retrospective Studies; D015431:Weight Loss / Q000502:physiology*
keywords: Eating behavior; Gastric stimulation; Morbid obesity; Obesity; Weight loss