title: The Use of Complementary and Alternative Medicine among Patients with Inflammatory Bowel Disease Is Associated with Reduced Health-Related Quality of Life.
abstract: Background and Aims.Complementary and alternative medicine (CAM) use among patients with inflammatory bowel disease (IBD) is common. The aim of this study was to explore associations between CAM use and health-related quality of life (HRQoL) as well as identifying whether sociodemographic factors, disease activity, and personal resources (self-efficacy) influence HRQoL scores in users and nonusers of CAM.Methods.Measures included sociodemographic and disease-related data, the International-CAM Questionnaire, and General Self-Efficacy Scale. A univariate analysis of variance was used to assess the association between CAM use and HRQoL. The associations between clinical, demographic, and personal factors and HRQoL were examined through linear regression analyses.Results.CAM users had statistically significant lower SF-36 scores compared to nonusers and the background population. Nonusers scored significantly lower compared to the background population in two out of the eight SF-36 dimensions. Independent of CAM use, disease activity had a negative impact and self-efficacy had a positive impact on HRQoL.Conclusions.HRQoL in CAM users with IBD was significantly lower compared to nonusers and the background population. Independent of CAM use, disease activity was negatively associated with HRQoL. Self-efficacy had a positive impact on the mental health dimensions in both CAM users and nonusers.
authors.affiliation: Department of Gastroenterology, Oslo University Hospital, Postboks 4959 Nydalen, 0424 Oslo, Norway; University of Oslo, Institute of Health and Society, Postboks 1072 Blindern, 0316 Oslo, Norway.
authors.forename: Randi
authors.identifier: 0000-0002-0513-1435
authors.initials: R
authors.lastname: Opheim
authors.affiliation: Department of Gastroenterology, Oslo University Hospital, Postboks 4959 Nydalen, 0424 Oslo, Norway.
authors.forename: Marte
authors.identifier: 0000-0002-0104-465X
authors.initials: M
authors.lastname: Lie Høivik
authors.affiliation: Telemark Hospital Trust, O&U, 3710 Skien, Norway; Institute of Clinical Medicine, University of Oslo, Postboks 1072 Blindern, 0316 Oslo, Norway.
authors.forename: Tomm
authors.initials: T
authors.lastname: Bernklev
authors.affiliation: Health Science, Østfold University College, Postboks 700, 1757 Halden, Norway; Department of Gastroenterology, Østfold Hospital Trust, Sarpsborg, Norway.
authors.forename: Lars-Petter
authors.identifier: 0000-0002-5465-1576
authors.initials: LP
authors.lastname: Jelsness-Jørgensen
authors.affiliation: Department of Gastroenterology, Oslo University Hospital, Postboks 4959 Nydalen, 0424 Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Postboks 1072 Blindern, 0316 Oslo, Norway.
authors.forename: Bjørn
authors.initials: B
authors.lastname: Moum