title: Thoughts on investigational hedgehog pathway inhibitors for the treatment of cancer.
authors.affiliation: a Department of Surgery , Paracelsus Medical University, Salzburger Landeskliniken (SALK) , Salzburg , Austria.
authors.forename: Tarkan
authors.initials: T
authors.lastname: Jäger
authors.affiliation: b Experimental Medicine Oncology , Bayer Pharma AG , Berlin , Germany.|c Department of Gastroenterology CBF , Charité University Medicine Berlin , Berlin , Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Ocker
authors.affiliation: d Department of Internal Medicine I , Paracelsus Medical University, Salzburger Landeskliniken (SALK) , Salzburg , Austria.|e Laboratory for Tumour Biology and Experimental Therapies (TREAT) , Institute of Physiology and Pathophysiology, Paracelsus Medical University , Salzburg , Austria.
authors.forename: Tobias
authors.initials: T
authors.lastname: Kiesslich
authors.affiliation: f Faculty of Chemistry , University of Vienna , Vienna , Austria.
authors.forename: Elen
authors.initials: E
authors.lastname: Neureiter
authors.affiliation: g Institute of Pathology , Paracelsus Medical University, Salzburger Landeskliniken (SALK) , Salzburg , Austria.|h Cancer Cluster Salzburg (CCS) , Salzburg , Austria.
authors.forename: Daniel
authors.initials: D
authors.lastname: Neureiter
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D015195:Drug Design; D015507:Drugs, Investigational / Q000494:pharmacology / Q000627:therapeutic use; D053823:Hedgehog Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D015507:Drugs, Investigational; D053823:Hedgehog Proteins
keywords: Hedgehog pathway; drug development; inhibitors