title: Comparison of Diagnostic Accuracy between Pulse Volume Recording Parameters and Exercise-Ankle-Brachial Pressure Index in Patients with Ankle-Brachial Pressure Index above 0.9.
abstract: Objective:The objective of this study was to clarify whether or not pulse volume recoding (PVR) parameters have screening capability equivalent to ankle-brachial pressure index after walking (Ex-ABI) for patients with 0.91 or higher ABI.Patients and Methods:The subjects were 87 patients (147 limbs) with symptoms of lower extremities with 0.91 or higher ABI. In all patients, upstroke time (UT), percentage of mean artery pressure (%MAP) of PVR and Ex-ABI were measured, and computed tomographic angiography (CTA) was concomitantly performed.Results:Area under the curve (AUC) of receiver operating characteristics (ROC) curves of Ex-ABI, %MAP, and UT were 0.90, 0.70, and 0.81, respectively. A significant difference was noted in AUC between Ex-ABI and %MAP (p <0.001). When the cut-off values were set at %MAP ≥45% and UT ≥180 msec, the accuracies of %MAP and UT were markedly lower than that of Ex-ABI. When the cut-off values were corrected to the values determined from the ROC curves (%MAP ≥41, UT ≥164 msec), the diagnostic accuracy of UT increased markedly.Conclusion:In patients with 0.91 or higher ABI, screening capability of PVR parameters was markedly lower than that of Ex-ABI, but UT has screening capability close to that of Ex-ABI when the cut-off value is corrected downward.
authors.affiliation: Laboratory of Physiology, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsuyuki
authors.affiliation: Laboratory of Physiology, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kohno
authors.affiliation: Laboratory of Physiology, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Miho
authors.initials: M
authors.lastname: Asaoka
authors.affiliation: Division of Cardiovascular Surgery, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Kunio
authors.initials: K
authors.lastname: Ebine
authors.affiliation: Division of Cardiovascular Surgery, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Tamura
authors.affiliation: Division of Cardiovascular Surgery, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ohzeki
authors.affiliation: Division of Cardiovascular Surgery, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Murase
authors.affiliation: Division of Cardiovascular Medicine, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Sugi
authors.affiliation: Division of Cardiovascular Medicine, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Kumagai
authors.affiliation: Division of Cardiovascular Medicine, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Itaru
authors.initials: I
authors.lastname: Yokouchi
authors.affiliation: Division of Cardiovascular Medicine, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamazaki
authors.affiliation: Division of Cardiovascular Medicine, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Tohi
authors.affiliation: Laboratory of Physiology, Odawara Cardiovascular Hospital, Odawara, Kanagawa, Japan; Department of Clinical Engineering, Kanagawa Institute of Technology, Atsugi, Kanagawa, Japan.
authors.forename: Mutsumi
authors.initials: M
authors.lastname: Sorimachi
authors.affiliation: Department of Clinical Engineering, Kanagawa Institute of Technology, Atsugi, Kanagawa, Japan.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Watanabe
keywords: ankle-brachial pressure index; peripheral arterial disease; pulse volume recording