title: The Value of the T2-Weighted Multipoint Dixon Sequence in MRI of Sacroiliac Joints for the Diagnosis of Active and Chronic Sacroiliitis.
abstract: OBJECTIVE
  The objective of this study was to determine the value of the T2-weighted multipoint Dixon technique as a single sequence in MRI of the sacroiliac joints for the diagnosis of active and chronic sacroiliitis.
  
  
  METHODS
  The T2-weighted multipoint Dixon sequence with water-only, in-phase, opposed-phase, and fat-only images was added to a routine MRI protocol, which included T1-weighted, fat-saturated T2-weighted, and contrast-enhanced fat-saturated T1-weighted sequences, for imaging 73 patients. Images obtained as part of the routine protocol were reviewed first by two radiologists. Then, the T2-weighted multipoint Dixon images were reviewed separately. Signs of active inflammation detected on fat-saturated T2-weighted and contrast-enhanced fat-saturated T1-weighted images were compared with the water-only images. Signs of chronic sacroiliitis detected on T1-weighted images were compared with the fat-only, in-phase, and opposed-phase images. Contrast-to-noise ratios (CNRs) of all lesions were statistically analyzed. ANOVA and posthoc Tukey tests were used to compare CNR data.
  
  
  RESULTS
  The mean CNR of 34 lesions with bone marrow edema or osteitis was greater on the water-only images (CNR, 176) than on the fat-saturated T2-weighted images (CNR, 82) and the contrast-enhanced fat-saturated T1-weighted images (CNR, 56), and this difference in mean CNRs was statistically significant (p < 0.01). There were also statistically significant differences in CNRs between sequences (p < 0.01). The highest mean CNR for subchondral sclerosis in 23 lesions was noted on in-phase images, and the highest mean CNR for periarticular fat deposition in 29 lesions was noted on opposed-phase images. Qualitative analyses also revealed that T2-weighted multipoint Dixon images were superior in showing signs of both active and chronic sacroiliitis.
  
  
  CONCLUSIONS
  The T2-weighted multipoint Dixon sequence is superior to conventional MRI sequences in depicting diagnostic signs of active and chronic sacroiliitis and therefore may be used as a single sequence.
authors.affiliation: 1 Department of Radiology, Yeditepe University, İçerenköy Mahallesi, Hastane Yolu Sokak, Number 102-104, Ataşehir, Istanbul 34752, Turkey.|2 Department of Radiology, Memorial Hospitals Group, Istanbul, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Özgen
mesh_terms: D000208:Acute Disease; D000328:Adult; D000465:Algorithms; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results; D012446:Sacroiliac Joint / Q000000981:diagnostic imaging*; D058566:Sacroiliitis / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio
keywords: MRI; sacroiliac joint; sacroiliitis; spondyloarthropathy