title: The impact of previous prostate surgery on the outcomes of laparoscopic radical prostatectomy.
abstract: The aim of this study was to evaluate the outcomes in laparoscopic radical prostatectomy (LRP) in patients who had undergone prior prostate surgery (PPS).
  
  
  
  In this study 946 consecutive LR P patients were included and a retrospective comparison between those patients who had received PPS (group A) and those who had not received PPS (group B) was carried out. The preoperative, intraoperative and postoperative data was collected in a prospectively-maintained database. All complications occurring ≤30 days after surgery were recorded and defined according to the Dindo-modification of the Clavien system.
  
  
  
  Longer operative time, greater blood loss, longer catheterization time, higher incidence of lymphocele, rectal injury and anastomotic stricture were found to be more frequent in group A. No statistically significant difference was noted between the two groups in terms of positive surgical margin rate and Biochemical recurrence free survival (BCRFS). Complete urinary continence rate resulted significantly higher in group B patients at both 1-year and 2-year follow-up. Potency rate resulted better in group B patients even if a statistically significant difference for both unilateral and bilateral nerve sparing techniques was not reached.
  
  
  
  LRP procedure can be safely performed on patients who have previously undergone PPS without compromising oncologic safety whereas a negative impact on functional outcome in terms of achieving a complete urinary continence rate and sexual potency should be expected.
authors.affiliation: Urology Unit, Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples "Federico II ", Naples, Italy - pverze@gmail.com.
authors.forename: Paolo
authors.initials: P
authors.lastname: Verze
authors.affiliation: Urology and Mini-Invasive Surgery Unit, Romolo Hospital, Rocca di Neto, Crotone, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Greco
authors.affiliation: Urology Unit, A. Manzoni Hospital, Lecco, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Scuzzarella
authors.affiliation: Urology and Mini-Invasive Surgery Unit, Romolo Hospital, Rocca di Neto, Crotone, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Bottone
authors.affiliation: Urology Unit, Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples "Federico II ", Naples, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Palmieri
authors.affiliation: Urology Unit, Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples "Federico II ", Naples, Italy.
authors.forename: Vito
authors.initials: V
authors.lastname: Cucchiara
authors.affiliation: Urology Unit, Department of Woman, Child and General and Specialized Surgery, Second University of Naples (SUN), Naples, Italy.
authors.forename: Davide
authors.initials: D
authors.lastname: Arcaniolo
authors.affiliation: Urology Unit, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Imperatore
authors.affiliation: Urology Unit, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Creta
authors.affiliation: Urology Unit, Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University of Naples "Federico II ", Naples, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Mirone
mesh_terms: D000368:Aged; D006801:Humans; D010535:Laparoscopy; D008297:Male; D011467:Prostate / Q000601:surgery*; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome