title: [IgA nephropathy - prognostic factors and treatment].
abstract: IgA nephropathy is the most common cause of primary glomerolunephritis. Patients who have isolated hematuria, little or no proteinuria (<0,5 g/d) and present with normal renal function usually have a low risk of progression. In patients with greater proteinuria and/or an elevation in the serum creatinine concentration, different rate of progression to end-stage renal disease has been observed. The approach to the management consists of nephroprotective therapies based on renin-angiotensin-aldosterone system blockade, which aim to slow progression of kidney damage, and, in some patients, immunosuppression.
authors.affiliation: Katedra i Klinika Nefrologii, Dializoterapii i Chorób Wewnętrznych WUM, Warszawa, Polska, monfeb@wp.pl.
authors.forename: Monika
authors.initials: M
authors.lastname: Wieliczko
authors.affiliation: Katedra i Klinika Nefrologii, Dializoterapii i Chorób Wewnętrznych WUM, Warszawa, Polska.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Dylewska
mesh_terms: D003404:Creatinine / Q000097:blood; D004359:Drug Therapy, Combination; D005919:Glomerular Filtration Rate; D005922:Glomerulonephritis, IGA / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007676:Kidney Failure, Chronic / Q000175:diagnosis* / Q000188:drug therapy*; D011379:Prognosis; D011507:Proteinuria / Q000175:diagnosis* / Q000188:drug therapy*; D012084:Renin-Angiotensin System / Q000187:drug effects
chemical_list: D007166:Immunosuppressive Agents; D003404:Creatinine
keywords:  immunosuppressive therapy ;  nephroprotection; IgA nephropathy