title: Primarily isolated hepatic involvement of amyloidosis: A case report and overview.
abstract: BACKGROUND
  Amyloidosis is particularly difficult to diagnose because the signs and symptoms are subtle. Additionally, there are no specific imaging or laboratory tests, except histopathology. Although it is considered to be a systemic disorder, a small portion of cases may be localized.
  A 54-year-old man presented with nonspecific symptoms (jaundice and back pruritus). Biochemical tests showed a high level of bilirubin and elevated serum tumor markers (CA19-9 and CA125). Routine imaging showed hepatomegaly without heterogeneous enhancement. Liver biopsy confirmed the diagnosis of hepatic amyloidosis. No cardiac or renal involvement was found. The patient accepted treatment involving oral chemotherapy.
  
  
  CONCLUSIONS
  A rare and unique presentation of hepatic amyloidosis was highlighted in this case.
authors.affiliation: Department of Gastroenterology and Hepatology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Ye
authors.forename: Hui
authors.initials: H
authors.lastname: Shi
authors.forename: Hui-Min
authors.initials: HM
authors.lastname: Wu
authors.forename: Fang-Yu
authors.initials: FY
authors.lastname: Wang
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology; D006529:Hepatomegaly / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D007565:Jaundice / Q000209:etiology; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011537:Pruritus / Q000209:etiology