title: Value of 3-Dimensional Speckle Tracking Echocardiography in the Prediction of Microvascular Obstruction and Left Ventricular Remodeling in Patients With ST-Elevation Myocardial Infarction.
abstract: In patients with myocardial infarction (MI), microvascular obstruction (MVO) determined by cardiac magnetic resonance imaging (CMR) is associated with left ventricular (LV) remodeling and worse prognosis.
  
  
  
  In 71 patients with ST-segment elevation MI (STEMI) treated by primary percutaneous coronary intervention (PCI), speckle tracking echocardiography (STE) and CMR were performed early after PCI. All patients underwent CMR at 6 months after hospital discharge to assess the occurrence of LV remodeling. The values of 3-dimensional (3D)-circumferential strain (CS), area change ratio (ACR), and 2-dimensional (2D)-CS were significantly different for the transmural extent of infarct, whereas the values of 3D- and 2D- longitudinal strain (LS) were not significantly different. In transmural infarct segments, the values of 3D-CS and ACR were significantly lower in segments with MVO than in those without MVO. At 6-month follow-up, LV remodeling was observed in 22 patients. In multivariable logistic regression models, global 3D-CS and ACR were significant determinants of LV remodeling rather than the number of MVO segments.
  
  
  
  Regional 3D-CS and ACR reflected the transmural extent of infarct and were significantly associated with the presence of MVO. In addition, global 3D-CS and ACR were preferable to the extent of MVO in the prediction of LV remodeling.
authors.affiliation: Cardiovascular Division, Faculty of Medicine, University of Tsukuba.
authors.forename: Akinori
authors.initials: A
authors.lastname: Sugano
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Seo
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ishizu
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Watabe
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Tomoko
authors.initials: T
authors.lastname: Machino-Ohtsuka
authors.forename: Yui
authors.initials: Y
authors.lastname: Takaiwa
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kakefuda
authors.forename: Hideaki
authors.initials: H
authors.lastname: Aihara
authors.forename: Yuko
authors.initials: Y
authors.lastname: Fumikura
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Nishina
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Noguchi
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Aonuma
mesh_terms: D000368:Aged; D019560:Echocardiography, Three-Dimensional; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D000072657:ST Elevation Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D020257:Ventricular Remodeling