title: Management of endometrial polyps incidentally diagnosed during IVF: a case-control study.
abstract: An endometrial polyp is a frequently encountered abnormality of the uterine cavity that may interfere with normal embryo implantation. In this case-control study, we enrolled 56 women in whom endometrial polyps were incidentally diagnosed by transvaginal ultrasound and office hysteroscopy during IVF (Group 1), and 112 age-matched IVF controls randomly selected from the same time period (group 2). Cryopreserved embryos were transferred in group 1 whereas fresh embryos were transferred in group 2, which is a limitation of the study. Hysteroscopic polypectomy was carried out for those in group 1, followed by vitrified-warmed embryo transfer 1-7 months later. Results revealed that the clinical pregnancy rate was higher in group 1 than in group 2 (63% versus 41%, P = 0.009), but the embryo implantation rates were not different between the two groups (26% versus 20%). In group 1, pregnancy rates (64%, 69%, and 53% respectively) and embryo implantation rates (30%, 24%, and 23%, respectively) were similar among women that received vitrified-warmed embryo transfer at 1, 2, and 3 months or over after hysteroscopic polypectomy. We conclude that, for women with endometrial polyps incidentally diagnosed during IVF, pregnancy outcomes are not compromised after hysteroscopic polypectomy followed by vitrified-warmed embryo transfer.
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital, 7 Chung-Shan South Road, 100, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address: jjhyang@gmail.com.
authors.forename: Jehn-Hsiahn
authors.initials: JH
authors.lastname: Yang
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital, 7 Chung-Shan South Road, 100, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
authors.forename: Po-Kai
authors.initials: PK
authors.lastname: Yang
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital, 7 Chung-Shan South Road, 100, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
authors.forename: Mei-Jou
authors.initials: MJ
authors.lastname: Chen
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital, 7 Chung-Shan South Road, 100, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
authors.forename: Shee-Uan
authors.initials: SU
authors.lastname: Chen
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital, 7 Chung-Shan South Road, 100, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
authors.forename: Yu-Shih
authors.initials: YS
authors.lastname: Yang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D015907:Hysteroscopy; D011127:Polyps / Q000175:diagnosis / Q000601:surgery*; D011247:Pregnancy; D018873:Pregnancy Rate; D014591:Uterine Diseases / Q000000981:diagnostic imaging / Q000601:surgery*
keywords: Endometrial polyp; Hysteroscopy; IVF; Infertility