title: Evolution of body weight parameters up to 3 years after solid organ transplantation: The prospective Swiss Transplant Cohort Study.
abstract: Obesity and weight gain are serious concerns after solid organ transplantation (Tx); however, no unbiased comparison regarding body weight parameter evolution across organ groups has yet been performed. Using data from the prospective nationwide Swiss Transplant Cohort Study, we compared the evolution of weight parameters up to 3 years post-Tx in 1359 adult kidney (58.3%), liver (21.7%), lung (11.6%), and heart (8.4%) recipients transplanted between May 2008 and May 2012. Changes in mean weight and body mass index (BMI) category were compared to reference values from 6 months post-Tx. At 3 years post-Tx, compared to other organ groups, liver Tx recipients showed the greatest weight gain (mean 4.8±10.4 kg), 57.4% gained >5% body weight, and they had the highest incidence of obesity (38.1%). After 3 years, based on their BMI categories at 6 months, normal weight and obese liver Tx patients, as well as underweight kidney, lung and heart Tx patients had the highest weight gains. Judged against international Tx patient data, the majority of our Swiss Tx recipients' experienced lower post-Tx weight gain. However, our findings show weight gain pattern differences, both within and across organ Tx groups that call for preventive measures.
authors.affiliation: Institute of Nursing Science, University of Basel, Basel, Switzerland.|Department of Abdomen-Metabolism, University Hospital Zurich, Zurich, Switzerland.
authors.forename: Sonja
authors.initials: S
authors.lastname: Beckmann
authors.affiliation: Department of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.
authors.forename: Nataša
authors.initials: N
authors.lastname: Nikolic
authors.affiliation: Institute of Nursing Science, University of Basel, Basel, Switzerland.
authors.forename: Kris
authors.initials: K
authors.lastname: Denhaerynck
authors.affiliation: Nephrology and Transplantation Medicine, Cantonal Hospital St Gallen, St Gallen, Switzerland.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Binet
authors.affiliation: Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland.
authors.forename: Michael
authors.initials: M
authors.lastname: Koller
authors.affiliation: University Hospital of Geneva, Geneva, Switzerland.
authors.forename: Elsa
authors.initials: E
authors.lastname: Boely
authors.affiliation: Institute of Nursing Science, University of Basel, Basel, Switzerland.|Department of Public Health and Primary Care, Academic Center for Nursing and Midwifery, KU Leuven, Leuven, Belgium.
authors.forename: Sabina
authors.initials: S
authors.lastname: De Geest
mesh_terms: D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology*; D016377:Organ Transplantation; D015995:Prevalence; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D013557:Switzerland / Q000453:epidemiology; D015430:Weight Gain
keywords: body mass index; obesity; organ transplantation; prospective study; underweight; weight gain