title: Pulmonary vascular remodeling in pulmonary hypertension.
abstract: Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension and involves changes in the intima, media and adventitia, often with the interplay of inflammatory cells. This review examines the pathology of these changes and highlights some of the pathogenetic mechanisms that underlie the remodeling process.
authors.affiliation: Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus Research 2, Room 9001, 12700 East 19th Avenue, Aurora, CO 80045, USA. rubin.tuder@ucdenver.edu.
authors.forename: Rubin M
authors.initials: RM
authors.lastname: Tuder
mesh_terms: D000818:Animals; D006801:Humans; D006976:Hypertension, Pulmonary / Q000473:pathology / Q000503:physiopathology*; D007249:Inflammation / Q000473:pathology; D066253:Vascular Remodeling
keywords: Endothelial cells; Lung; Pulmonary hypertension; Pulmonary remodeling; Smooth muscle cells