title: Vaginal epithelioid angiosarcoma: a rare case.
abstract: Epithelioid angiosarcoma of the vagina is a rare variant, easily misdiagnosed as other epithelial neoplasms. On Hematoxylin-Eosin-stained sections, the pathologist encounters sheets of large, mildly to moderately pleomorphic epithelioid cells, with abundant eosinophilic cytoplasm, vesicular nuclei, and prominent nucleoli. We report the case of a 22-year-old woman initially diagnosed with condiloma-like tumor of the left vaginal wall, which turned out positive at immunostaining for epithelioid angiosarcoma. In her case, after the failure of chemotherapy in controlling the relapse of the disease, the only treatment option was radical hysterectomy with bilateral salpingo-oophorectomy.
authors.affiliation: Department of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova, Emergency University Hospital of Craiova, Romania; dr_berceanu@yahoo.com.
authors.forename: Elvira
authors.initials: E
authors.lastname: Brătilă
authors.forename: Oana Maria
authors.initials: OM
authors.lastname: Ionescu
authors.forename: Costin
authors.initials: C
authors.lastname: Berceanu
authors.forename: Ciprian Andrei
authors.initials: CA
authors.lastname: Coroleucă
authors.forename: Carmen Maria
authors.initials: CM
authors.lastname: Ardeleanu
authors.forename: Claudia
authors.initials: C
authors.lastname: MehedinŢu
mesh_terms: D000328:Adult; D015622:Epithelioid Cells / Q000473:pathology*; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology*; D006801:Humans; D014621:Vagina / Q000473:pathology*; D055815:Young Adult