title: Management of complex perianal Crohn's disease.
abstract: Patients with Crohn's disease often develop perianal disease, successfully managed in most cases. However, its most aggressive form, complex perianal disease, is associated with high morbidity and a significant impairment in patients' quality of life. The aim of this review is to provide an updated approach to this condition, reviewing aspects of its epidemiology, diagnosis and therapeutic alternatives. Emerging treatment options are also discussed. A multidisciplinary assessment of these patients with a coordinated medical and surgical approach is crucial.
authors.affiliation: Gastroenterology and Hepatology Department, University Hospital Ramón y Cajal (affiliated with Universidad de Alcalá), Madrid, Spain.
authors.forename: Lara
authors.initials: L
authors.lastname: Aguilera-Castro
authors.affiliation: Gastroenterology and Hepatology Department, University Hospital Ramón y Cajal (affiliated with Universidad de Alcalá), Madrid, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Ferre-Aracil
authors.affiliation: Gastroenterology and Hepatology Department, University Hospital Ramón y Cajal (affiliated with Universidad de Alcalá), Madrid, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Garcia-Garcia-de-Paredes
authors.affiliation: Gastroenterology and Hepatology Department, University Hospital Ramón y Cajal (affiliated with Universidad de Alcalá), Madrid, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Rodriguez-de-Santiago
authors.affiliation: Gastroenterology and Hepatology Department, University Hospital Ramón y Cajal (affiliated with Universidad de Alcalá), Madrid, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Lopez-Sanroman
keywords: Crohn’s disease; perianal abscess; perianal disease; perianal fistula