title: Slow generation of hydrogen sulfide from sulfane sulfurs and NADH models.
abstract: Here we report the model studies of the reactions between NADH models (using HEH and BNAH) and sulfane sulfurs (using polysulfides). Such reactions could lead to the oxidation of NADH models and the production of hydrogen sulfide (H2S). Kinetics of the reaction between BNAH and elemental sulfur S8were determined in ethanol and the second-order rate constant was found to be 0.074M-1min-1(at 37°C) suggesting this is a slow process.
authors.affiliation: Department of Chemistry, Washington State University, Pullman, WA 99164, USA.
authors.forename: Bo
authors.initials: B
authors.lastname: Peng
authors.affiliation: Department of Chemistry, Washington State University, Pullman, WA 99164, USA.
authors.forename: Chunrong
authors.initials: C
authors.lastname: Liu
authors.affiliation: Cardiovascular Center of Excellence, Louisiana State University Health Science Center, New Orleans, LA 70112, USA.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Chemistry, Washington State University, Pullman, WA 99164, USA.
authors.forename: Jacob J
authors.initials: JJ
authors.lastname: Day
authors.affiliation: Department of Chemistry, Southern Illinois University Edwardsville, Edwardsville, IL 62026, USA.
authors.forename: Yun
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Cardiovascular Center of Excellence, Louisiana State University Health Science Center, New Orleans, LA 70112, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Lefer
authors.affiliation: Department of Chemistry, Washington State University, Pullman, WA 99164, USA. Electronic address: mxian@wsu.edu.
authors.forename: Ming
authors.initials: M
authors.lastname: Xian
mesh_terms: D006862:Hydrogen Sulfide / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009243:NAD / Q000737:chemistry*; D010084:Oxidation-Reduction; D013457:Sulfur Compounds / Q000737:chemistry*
chemical_list: D013457:Sulfur Compounds; D009243:NAD; D006862:Hydrogen Sulfide
keywords: Ammonium tetrathiomolybdate; Donor; Hydrogen sulfide; Oxidative damage