title: A Phage-Like IncY Plasmid Carrying themcr-1Gene in Escherichia coli from a Pig Farm in China.
abstract: We report here a new type of plasmid that carries themcr-1gene, the pMCR-1-P3 plasmid, harbored in anEscherichia colistrain isolated from a pig farm in China. pMCR-1-P3 belongs to the IncY incompatibility group and is a phage-like plasmid that contains a large portion of phage-related sequences. The backbone of this plasmid is different from that of othermcr-1-carrying plasmids reported previously.
authors.affiliation: China Institute of Veterinary Drug Control, Beijing, China.
authors.forename: Chunping
authors.initials: C
authors.lastname: Zhang
authors.affiliation: CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.|Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing, China.|University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Feng
authors.affiliation: CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.|Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.|Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.affiliation: China Institute of Veterinary Drug Control, Beijing, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Jiang
authors.affiliation: China Animal Health and Epidemiology Center, Qingdao, China.
authors.forename: Zhina
authors.initials: Z
authors.lastname: Qu
authors.affiliation: Core Genomic Facility of Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Lei
authors.affiliation: Core Genomic Facility of Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Wang
authors.affiliation: Core Genomic Facility of Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Zhang
authors.affiliation: CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.|Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.|Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing, China.
authors.forename: Yongfei
authors.initials: Y
authors.lastname: Hu
authors.affiliation: China Institute of Veterinary Drug Control, Beijing, China dingjiabo@126.com zhubaoli@im.ac.cn.
authors.forename: Jiabo
authors.initials: J
authors.lastname: Ding
authors.affiliation: CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China dingjiabo@126.com zhubaoli@im.ac.cn.|Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.|Beijing Key Laboratory of Microbial Drug Resistance and Resistome, Beijing, China.
authors.forename: Baoli
authors.initials: B
authors.lastname: Zhu
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D001435:Bacteriophages / Q000235:genetics / Q000378:metabolism; D001483:Base Sequence; D002681:China; D004926:Escherichia coli / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D029968:Escherichia coli Proteins / Q000235:genetics* / Q000378:metabolism; D015870:Gene Expression; D016366:Open Reading Frames; D010957:Plasmids / Q000737:chemistry* / Q000378:metabolism; D017422:Sequence Analysis, DNA; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*
chemical_list: D029968:Escherichia coli Proteins; C000614037:MCR-1 protein, E coli
keywords: DNA sequencing; antibiotics; plasmid