title: Type 2 diabetes and mental disorders; a plausible link with inflammation.
abstract: Mental disorders including depression and anxiety are the prevalent human diseases which are associated with several metabolic and non-metabolic diseases. Recent investigations demonstrated that the mental disorders can be considered as the potential inducers/stimulators of chronic inflammation. Based on the fact that chronic inflammation is a main cause of human diseases, hence, a hypothesis has been raised to explore the interaction between mental disorders and inflammation related metabolic diseases. Type 2 diabetes (T2D), as a complicated metabolic disorder, is associated with inflammation and also mental disorders. Accordingly, it has been hypothesized that depression and anxiety, as mental disorders may be the inducers/stimulators of inflammation in the patients suffering from T2D. This review article collected recent information regarding the roles of mental disorders on the chronic inflammation in the T2D patients.
authors.affiliation: Dept. of Psychology, Faculty of Humanity, Science and Research Branch, Islamic Azad University, Tehran, Iran.
authors.forename: B
authors.initials: B
authors.lastname: Hajebrahimi
authors.affiliation: Dept. of Psychology, Faculty of Humanity, Science and Research Branch, Islamic Azad University, Tehran, Iran.
authors.forename: A
authors.initials: A
authors.lastname: Kiamanesh
authors.affiliation: Mental Health Research Center, Department of Clinical Psychology, Tehran Institute of Psychiatry, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: A A
authors.initials: AA
authors.lastname: Asgharnejad Farid
authors.affiliation: Neuroscience Research Center, Institute of Neuropharmacology Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: G
authors.initials: G
authors.lastname: Asadikaram
mesh_terms: D001007:Anxiety; D016207:Cytokines / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000473:pathology*; D006801:Humans; D007249:Inflammation; D001523:Mental Disorders / Q000473:pathology*
chemical_list: D016207:Cytokines