title: Vulvovaginal gingival lichen planus: report of two cases and review of literature.
abstract: OBJECTIVE
  Oral Lichen Planus (OLP) is a chronic inflammatory disease of skin and mucous membranes. Approximately 20% of women with oral lichen planus develops lesions in the genital mucosa. In 1982, Pelisse described a special form of lichen planus (LP), which consists of a triad of symptoms: vulval, vaginal and gingival (VVG)-LP lesions. Aim of the present report is to report two new cases and review the international literature.
  
  
  METHODS
  Two cases of VVG-LP are reported and a review of recent literature is performed.
  
  
  RESULTS
  The onset of erosive or ulcerative mouth lesions may precede or follow by months or even years the onset of vulvovaginal lesions. Vaginal agglutination is associated with the postmenopausal state in conjunction with a dermatologic condition. Intra-lesional corticosteroids have a role in localized chronic ulceration, while systemic therapies such as corticosteroids, azathioprine, mycophenolate mofetil, hydroxychloroquine, ciclosporin, methotrexate, retinoids, thalidomide and photo chemotherapy have been used in more severe cases with varying success.
  
  
  CONCLUSIONS
  VVG-LP is rather a rare condition and has been documented in the literature mainly in the form of case reports. Lack of a precise diagnostic criteria of VVG-LP depends on the specialists.
authors.affiliation: Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Lucchese
authors.affiliation: Department of Clinical Science and Translational Medicine, University of Rome "Tor Vergata", Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Dolci
authors.affiliation: Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Naples, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Minervini
authors.affiliation: Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Naples, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Salerno
authors.affiliation: Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Naples, Italy.
authors.forename: D
authors.initials: D
authors.lastname: DI Stasio
authors.affiliation: Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Naples, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Minervini
authors.affiliation: Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Naples, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Laino
authors.affiliation: Departimento de Estomatologia, University of Valencia, Valencia, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Silvestre
authors.affiliation: Multidisciplinary Department of Medical-Surgical and Dental Specialties, Second University of Naples, Naples, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Serpico
keywords: and oral diseases; oral lichen planus; peno-gignival lichen planus; vaginal agglutination; vulvovaginal gingival syndrome