title: Prospective study on factors affecting the prognosis of oral cancer in a Chinese population.
abstract: This study was performed to identify the factors affecting prognosis of oral cancer patients. 1240 pathologically confirmed oral cancer patients were included. The sociodemographic and clinical characteristics of all patients were collected. Univariate and multivariate Cox proportional hazards models were used to assess potential prognostic factors for survival. 1240 oral cancer patients were followed up for 49235.00 person months, and the 5-year overall survival rate was 64.38%. Both univariate and multivariate Cox regression analysis indicated that Body Mass Index < 18.5 kg/m2 (vs 18.5-23.9 kg/m2), age ≥ 55 years (vs < 55 years), clinical stages of II-IV (vs stage I), and poor differentiation (vs well differentiation) were associated with worse survival of oral cancer patients. While surgery (vs non-surgery) and origin of urban area (vs rural area) were protective factors. However, no significant association was found between adjuvant therapy and survival in oral cancer patients.
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Fengqiong
authors.initials: F
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Fa
authors.initials: F
authors.lastname: Chen
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Jiangfeng
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Lingjun
authors.initials: L
authors.lastname: Yan
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Fangping
authors.initials: F
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Junfeng
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Stomatology, The First Affiliated Hospital of Fujian Medical University, Fujian, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Qiu
authors.affiliation: Department of Stomatology, The First Affiliated Hospital of Fujian Medical University, Fujian, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Rongzhao
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Department of Stomatology, The First Affiliated Hospital of Fujian Medical University, Fujian, China.
authors.forename: Lisong
authors.initials: L
authors.lastname: Lin
authors.affiliation: Department of Epidemiology and Health Statistic, Fujian Provincial Key Laboratory of Environment factors and Cancer, School of Public Health, Fujian Medical University, Fujian, China.
authors.forename: Baochang
authors.initials: B
authors.lastname: He
mesh_terms: D000368:Aged; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000401:mortality* / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D016019:Survival Analysis; D015996:Survival Rate
keywords: BMI; chemotherapy; oral cancer; prognosis; radiotherapy