title: Silver-catalysed tandem hydroamination and cyclization of 2-trifluoromethyl-1,3-enynes with primary amines: modular entry to 4-trifluoromethyl-3-pyrrolines.
abstract: A highly efficient tandem hydroamination and cyclization reaction of 2-trifluoromethyl-1,3-enynes with primary amines leading to 4-trifluoromethyl-3-pyrrolines was developed by using AgNO3as a catalyst under mild reaction conditions. This new method is compatible with alkyl, aryl, and allyl primary amines, representing an atom-economical protocol for the construction of 4-trifluoromethyl-3-pyrrolines for the first time.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, 200062, P. R. China. yjxiao@chem.ecnu.edu.cn jlzhang@chem.ecnu.edu.cn.
authors.forename: Xiaofan
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, 200062, P. R. China. yjxiao@chem.ecnu.edu.cn jlzhang@chem.ecnu.edu.cn.
authors.forename: Chaoqian
authors.initials: C
authors.lastname: Huang
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, 200062, P. R. China. yjxiao@chem.ecnu.edu.cn jlzhang@chem.ecnu.edu.cn.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zeng
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, 200062, P. R. China. yjxiao@chem.ecnu.edu.cn jlzhang@chem.ecnu.edu.cn.
authors.forename: Jiarui
authors.initials: J
authors.lastname: Xiong
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, 200062, P. R. China. yjxiao@chem.ecnu.edu.cn jlzhang@chem.ecnu.edu.cn.
authors.forename: Yuanjing
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Road, Shanghai, 200062, P. R. China. yjxiao@chem.ecnu.edu.cn jlzhang@chem.ecnu.edu.cn.
authors.forename: Junliang
authors.identifier: http://orcid.org/0000-0002-4636-2846
authors.initials: J
authors.lastname: Zhang