title: Spontaneous Intracranial Hypotension With Site of Leak Detected Only After 111In-DTPA Cisternogram.
abstract: A 54-year-old man with a 3-week history of orthostatic headache and acute on chronic subdural hematoma presented with imaging findings suggestive of spontaneous intracranial hypotension. Three myelograms were negative for leak, and nontargeted epidural blood patches did not result in symptom relief. A cerebrospinal fluid leak study using In-DTPA with SPECT/CT demonstrated a focal area of asymmetric activity at the left C2 nerve root. A left C2 root tie-off, targeted epidural blood patch, and Dura seal glue resulted in resolution of patient symptomatology highlighting the importance of fused SPECT/CT images in detection of an occult cerebral spinal fluid leak.
authors.affiliation: From the Departments of *Radiology, and †Nuclear Medicine, University of Washington, Seattle, WA.
authors.forename: Sana
authors.initials: S
authors.lastname: Parsian
authors.forename: Manuela C
authors.initials: MC
authors.lastname: Matesan
authors.forename: Sachin Shivaji
authors.initials: SS
authors.lastname: Kumbhar
authors.forename: David H
authors.initials: DH
authors.lastname: Lewis
mesh_terms: D065634:Cerebrospinal Fluid Leak / Q000000981:diagnostic imaging*; D006801:Humans; D007205:Indium Radioisotopes; D019585:Intracranial Hypotension / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009192:Myelography; D004369:Pentetic Acid; D019275:Radiopharmaceuticals; D000072098:Single Photon Emission Computed Tomography Computed Tomography
chemical_list: D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; D004369:Pentetic Acid