title: Ofloxacin Induced Angioedema: A Rare Adverse Drug Reaction.
abstract: The Adverse Drug Reaction (ADR) to a commonly prescribed anti-microbial can pose a major public health problem. The authors report a rare case of 24-year-old young lady who presented with angioedema of lips after ingestion of Ofloxacin, prescribed to her for treatment of loose motions. Fluoroquinolones are widely prescribed antibiotics for various disease conditions. The history, clinical examination and normal laboratory parameters led to the diagnosis of ofloxacin induced hypersensitivity reaction and the patient was successfully treated with corticosteroids and antihistamines. The hypersensitivity reactions to fluoroquinolones are rare with an incidence of 0.4% to 2%. The pharmacovigilance program and self-reporting of all the ADR's by the health care workers can help in ensuring the judicious use of the drug, drug safety and thus decrease the associated morbidity and mortality.
authors.affiliation: Attending Consultant-Respiratory Intensive Care, Max Super Specialty Hospital , Saket, New Delhi, India .
authors.forename: Gautam
authors.initials: G
authors.lastname: Rawal
authors.affiliation: General Duty Medical Officer-II, Department of Medicine & TB, Chest Clinic Moti Nagar, North Delhi Municipal Corporation, New Delhi, India .
authors.forename: Sankalp
authors.initials: S
authors.lastname: Yadav
authors.affiliation: Senior Consultant and Incharge-Respiratory Intensive Care, Max Super Specialty Hospital , Saket, New Delhi, India .
authors.forename: Raj
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Clinical Associate, Critical Care, Max Super Specialty Hospital , Vaishali, Ghaziabad, Uttar Pradesh, India .
authors.forename: Umar Rasool
authors.initials: UR
authors.lastname: Wani
keywords: Fluoroquinolones; Hypersensitivity; Pharmacovigilance