title: Genetic polymorphisms of human platelet antigens in Euro-African and Japanese descendants from Parana, Southern Brazil.
abstract: The frequency distributions of HPA-1 to HPA-6 and HPA-15 were evaluated in two Brazilian populations from Parana: a mixed population of predominantly Caucasians and a population of Japanese descendants. Genotyping was performed by PCR-SSP in 364 unrelated individuals. Differences in the distribution of HPA highlight diversity in Brazilian miscegenation and the importance of formation of the HPA panel composed of regional blood donors.
authors.affiliation: a Post Graduation Program of Biosciences and Physiopathology, Biomedicine and Clinical Analysis Department , Maringa State University , Maringa , Brazil.
authors.forename: Ana Paula Avenia
authors.initials: APA
authors.lastname: Silvestre
authors.affiliation: a Post Graduation Program of Biosciences and Physiopathology, Biomedicine and Clinical Analysis Department , Maringa State University , Maringa , Brazil.
authors.forename: Joana Maira Valentini
authors.initials: JMV
authors.lastname: Zacarias
authors.affiliation: b Albert Einstein Israelita Hospital , São Paulo , Brazil.
authors.forename: Gláucia Andréia Soares
authors.initials: GAS
authors.lastname: Guelsin
authors.affiliation: a Post Graduation Program of Biosciences and Physiopathology, Biomedicine and Clinical Analysis Department , Maringa State University , Maringa , Brazil.|c Basic Health Sciences Department , Maringa State University , Maringa , Brazil.
authors.forename: Jeane Eliete Laguila
authors.initials: JEL
authors.lastname: Visentainer
authors.affiliation: a Post Graduation Program of Biosciences and Physiopathology, Biomedicine and Clinical Analysis Department , Maringa State University , Maringa , Brazil.
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Sell
mesh_terms: D000483:Alleles; D016824:Antigens, Human Platelet / Q000235:genetics*; D044466:Asian People / Q000235:genetics*; D044383:Black People / Q000235:genetics*; D001938:Brazil; D005260:Female; D005787:Gene Frequency; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics*; D044465:White People / Q000235:genetics*
chemical_list: D016824:Antigens, Human Platelet
keywords: Allele frequency; HPA; genotyping; polymorphisms