title: Copper-catalyzed C-O bond cleavage and cyclization: synthesis of indazolo[3,2-b]quinazolinones.
abstract: The first example of a copper-catalyzed halogen-free protocol to construct indazolo[3,2-b]quinazolinones was developed through sequential inert C-O bond cleavage followed by intramolecular C-N bond formation. This protocol represents an efficient synthetic tool for accessing a more diverse range of functionalized indazolo[3,2-b]quinazolinones. The structure of the newly synthesized indazolo[3,2-b]quinazolinones was unambiguously confirmed by X-ray crystal diffraction analysis.
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Rui
authors.initials: R
authors.lastname: Qiao
authors.affiliation: The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, P. R. China.
authors.forename: Leping
authors.initials: L
authors.lastname: Ye
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Kun
authors.initials: K
authors.lastname: Hu
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Shuling
authors.initials: S
authors.lastname: Yu
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Weiguang
authors.initials: W
authors.lastname: Yang
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Miaochang
authors.initials: M
authors.lastname: Liu
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Jiuxi
authors.identifier: http://orcid.org/0000-0001-6666-9813
authors.initials: J
authors.lastname: Chen
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Jinchang
authors.initials: J
authors.lastname: Ding
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China. jiuxichen@wzu.edu.cn huayuewu@wzu.edu.cn.
authors.forename: Huayue
authors.initials: H
authors.lastname: Wu