title: Immunoglobulin G4-related disease presenting as a pulmonary nodule with an irregular margin.
abstract: We report a case of immunoglobulin G4 (IgG4)-related lung disease presenting as a solitary pulmonary nodule with an irregular margin on computed tomography. The nodule showed a high standardized uptake value on positron emission tomography. A malignant pulmonary tumour could not be excluded. Middle lobectomy was performed. Histological analysis revealed marked lymphoplasmacytic infiltration and storiform fibrosis. Immunostaining indicated the presence of IgG4-positive plasma cells. A definitive diagnosis of IgG4-related disease was confirmed.
authors.affiliation: Department of Thoracic Surgery Tonan Hospital Sapporo Japan.
authors.forename: Tetsuyuki
authors.initials: T
authors.lastname: Okubo
authors.affiliation: Department of Diagnostic Pathology Tonan Hospital Sapporo Japan.
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Oyamada
authors.affiliation: Department of Thoracic Surgery Tonan Hospital Sapporo Japan.
authors.forename: Masaya
authors.initials: M
authors.lastname: Kawada
authors.affiliation: Department of Surgery Tonan Hospital Sapporo Japan.
authors.forename: Yo
authors.initials: Y
authors.lastname: Kawarada
authors.affiliation: Department of Surgery Tonan Hospital Sapporo Japan.
authors.forename: Shuji
authors.initials: S
authors.lastname: Kitashiro
authors.affiliation: Department of Surgery Tonan Hospital Sapporo Japan.
authors.forename: Shunichi
authors.initials: S
authors.lastname: Okushiba
keywords: Immunoglobulin G4‐related disease; immunoglobulin G4‐related lung disease; irregular margin; lung cancer; solitary pulmonary nodule