title: Are biventricular systolic functions impaired in patient with coronoray slow flow? A prospective study with three dimensional speckle tracking.
abstract: The newly developed three dimensional speckle-tracking echocardiography (3D-STE) technology provides quick and comprehensive quantitative assessment of biventricular myocardial dynamics. The impact of coronary slow flow phenomenon (CSFP) on biventricular functions has not been comprehensively evaluated using this new technology. Therefore, the aim of this study was to evaluate the effects of CSFP on biventricular systolic functions using 3D-STE. Forty patients with CSFP and otherwise normal coronary arteries (NCAs) and 40 age- and sex-matched controls with normal coronary angiograms (CAGs) were prospectively enrolled. Biventricular systolic function was evaluated by 3D-STE. Left ventricular (LV) global longitudinal, circumferential and radial strains, ejection fraction (EF) were significantly lower and LV end-systolic volume (ESV) was significantly higher in the CSFP group compared to the control group. There were no significant differences in LV mass, LV end-diastolic volume (EDV) or LV stroke volume (SV). Additionally, Right ventricular (RV) free wall, septal wall and global longitudinal strains, and RV EF were significantly lower in the CSFP group, but there were no significant differences in RV EDV, ESV and RV SV. The present study demonstrated that CSFP has a notable negative effect on not only 3D strain parameters but also biventricular EF. There was a strong correlation between the strain parameters of the affected vessel's myocardial area and the TIMI frame count of same vessel.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Bahçeşehir University, Istanbul, Turkey. tugbakemalogluoz@gmail.com.
authors.forename: Tuğba
authors.initials: T
authors.lastname: Kemaloğlu Öz
authors.affiliation: Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Eren
authors.affiliation: Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
authors.forename: Işıl
authors.initials: I
authors.lastname: Atasoy
authors.affiliation: Department of Cardiology, Faculty of Medicine, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Tayfun
authors.initials: T
authors.lastname: Gürol
authors.affiliation: Department of Cardiology, Faculty of Medicine, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Özer
authors.initials: Ö
authors.lastname: Soylu
authors.affiliation: Department of Cardiology, Faculty of Medicine, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Bahadır
authors.initials: B
authors.lastname: Dağdeviren
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003326:Coronary Circulation; D019560:Echocardiography, Three-Dimensional; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D054318:No-Reflow Phenomenon / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011237:Predictive Value of Tests; D011446:Prospective Studies; D013318:Stroke Volume; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right
keywords: Coronary slow flow phenomenon; Echocardiography; Speckle tracking; Systolic function; Three dimensional echocardiography; Three dimensional speckle tracking