title: Iodine-mediatedsp³C-H functionalization of methyl ketones: a one-pot synthesis of functionalized indolizines via the 1,3-dipolar cycloaddition reaction between pyridinium ylides and ynones.
abstract: An efficient transition-metal-free approach toward C-H bond activation by using molecular [Formula: see text]-mediated [Formula: see text] C-H bond functionalization for the synthesis of indolizine derivatives via 1,3-dipolar cycloaddition reaction of nitrogen ylides with ynones is described.
authors.affiliation: Department of Chemistry, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran. yavarisa@modares.ac.ir.
authors.forename: Issa
authors.initials: I
authors.lastname: Yavari
authors.affiliation: Department of Chemistry, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran.
authors.forename: Jamil
authors.initials: J
authors.lastname: Sheykhahmadi
authors.affiliation: Department of Chemistry, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Naeimabadi
authors.affiliation: Department of Inorganic Chemistry, Chemistry and Chemical Engineering Research Center of Iran, PO Box 14335-186, Tehran, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Halvagar
mesh_terms: D002384:Catalysis; D061565:Cycloaddition Reaction; D007212:Indolizines / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D011725:Pyridines / Q000737:chemistry*
chemical_list: D007212:Indolizines; D007659:Ketones; D011725:Pyridines; C035094:indolizine; D007455:Iodine; C023666:pyridine
keywords: 1, 3-Dipolar cycloaddition; C–H activation; Indolizines; Iodine; N-ylides; Ynones