title: Current Status of Exposed Endoscopic Full-Thickness Resection and Further Development of Non-Exposed Endoscopic Full-Thickness Resection.
abstract: Endoscopic full-thickness resection (EFTR) is a procedure that makes it possible to access the lesions that are on the wall of the digestive tract via the shortest distance through the mouth. Because of the ultra-minimal invasive nature of the treatment, pure EFTR is a highly promising surgical procedure that allows the radical excision of full-thickness layers of digestive tract tumors using only a flexible endoscope. There are 2 types of EFTR methods: exposed and non-exposed. Considering the risks of contracting infection and intraperitoneal dissemination of tumor cells, non-exposed EFTR is an ideal method. However, a number of issues remain unresolved, including the method for performing a full-thickness suture under endoscopic view and the challenge of securing the operating field in the case of gastrointestinal tract collapse. Moreover, advances in the development of equipment such as full-thickness suturing devices would be helpful to make this therapeutic procedure the most minimally invasive endoscopic surgery ever.
authors.affiliation: Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu, Japan.
authors.forename: Hirohito
authors.initials: H
authors.lastname: Mori
authors.forename: Asadur
authors.initials: A
authors.lastname: Rahman
authors.forename: Hideki
authors.initials: H
authors.lastname: Kobara
authors.forename: Shintaro
authors.initials: S
authors.lastname: Fujihara
authors.forename: Noriko
authors.initials: N
authors.lastname: Nishiyama
authors.forename: Maki
authors.initials: M
authors.lastname: Ayaki
authors.forename: Tae
authors.initials: T
authors.lastname: Matsunaga
authors.forename: Masanori
authors.initials: M
authors.lastname: Murakami
authors.forename: Tsumomu
authors.initials: T
authors.lastname: Masaki
mesh_terms: D000069916:Endoscopic Mucosal Resection / Q000379:methods*; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005770:Gastrointestinal Neoplasms / Q000601:surgery*; D041981:Gastrointestinal Tract / Q000601:surgery; D006801:Humans; D009055:Mouth; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods*; D013536:Suture Techniques / Q000639:trends