title: Oral, Slow-Release Ivermectin: Biting Back at Malaria Vectors.
abstract: Bellinger and colleagues offer an elegant twist for a promising new tool against malaria. This formulation is designed to release ivermectin, a mosquito-killing drug for 10 days after a single oral dose. This could reduce the vector population and serve as a complementary tool for malaria elimination.
authors.affiliation: ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique; Instituto de Salud Tropical Universidad de Navarra, Pamplona, Spain. Electronic address: carlos.chaccour@isglobal.org.
authors.forename: Carlos J
authors.initials: CJ
authors.lastname: Chaccour
authors.affiliation: ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat de Barcelona, Barcelona, Spain; Harvard T.H. Chan School of Public Health, Boston, USA.
authors.forename: N Regina
authors.initials: NR
authors.lastname: Rabinovich
mesh_terms: D000284:Administration, Oral; D000818:Animals; D003692:Delayed-Action Preparations / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology; D006801:Humans; D007303:Insect Vectors / Q000187:drug effects; D007306:Insecticides / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology; D007559:Ivermectin / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000494:pharmacology; D008288:Malaria / Q000188:drug therapy / Q000517:prevention & control*; D009032:Mosquito Control / Q000379:methods*
chemical_list: D003692:Delayed-Action Preparations; D007306:Insecticides; D007559:Ivermectin
keywords: endectocide; ivermectin; malaria elimination; mass drug administration; slow-release; vector control