title: Mesenchymal MicroRNA Function Branches Out.
abstract: Significant amounts of microRNAs (miRs) are detected in exosomes, but their function during fetal development is poorly understood. In this issue of Developmental Cell, Hayashi et al. (2017) show that exosomal miRs secreted by mesenchymal cells can regulate epithelial KIT+progenitor cell expansion during murine salivary gland organogenesis.
authors.affiliation: Iowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA; Craniofacial Anomalies Research Center, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA; Department of Endodontics, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Huojun
authors.initials: H
authors.lastname: Cao
authors.affiliation: Iowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA; Craniofacial Anomalies Research Center, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA; Department of Prosthodontics, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Liu
authors.initials: L
authors.lastname: Hong
authors.affiliation: Iowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA; Craniofacial Anomalies Research Center, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA; Department of Orthodontics, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA; Department of Anatomy and Cell Biology, Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA. Electronic address: brad-amendt@uiowa.edu.
authors.forename: Brad A
authors.initials: BA
authors.lastname: Amendt
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D055354:Exosomes / Q000235:genetics*; D051379:Mice; D035683:MicroRNAs / Q000235:genetics*; D038081:Organogenesis; D012469:Salivary Glands / Q000196:embryology
chemical_list: D035683:MicroRNAs