title: Serial measurements of transrenal mycobacterial DNA as indicators of the early bactericidal activity (EBA) of antituberculosis drugs.
authors.affiliation: Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany; German Center for Infection Research, Clinical Tuberculosis Center, Borstel, Germany. Electronic address: jheyckendorf@fz-borstel.de.
authors.forename: Jan
authors.initials: J
authors.lastname: Heyckendorf
authors.affiliation: Alere Technologies GmbH, Jena, Germany.
authors.forename: Ines
authors.initials: I
authors.lastname: Labugger
authors.affiliation: Task Applied Science, Bellville, South Africa.
authors.forename: Lize
authors.initials: L
authors.lastname: van der Merwe
authors.affiliation: Centro de Investigação em Saúde de Manhiça (CISM), Vila da Manhiça, Maputo, Mozambique; Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain; Amsterdam Institute for Global Health and Development, Academic Medical Centre, Amsterdam, The Netherlands.
authors.forename: Alberto L
authors.initials: AL
authors.lastname: Garcia-Basteiro
authors.affiliation: Task Applied Science, Bellville, South Africa; Stellenbosch University, Tygerberg, South Africa.
authors.forename: Andreas H
authors.initials: AH
authors.lastname: Diacon
authors.affiliation: Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany; German Center for Infection Research, Clinical Tuberculosis Center, Borstel, Germany; International Health/Infectious Diseases, University of Lübeck, Lübeck, Germany; Department of Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Internal Medicine, University of Namibia School of Medicine, Windhoek, Namibia.
authors.forename: Christoph
authors.initials: C
authors.lastname: Lange
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D001431:Bacteriological Techniques; D004269:DNA, Bacterial / Q000652:urine*; D016903:Drug Monitoring / Q000379:methods; D006801:Humans; D007668:Kidney / Q000382:microbiology*; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000235:genetics; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D013183:Sputum / Q000382:microbiology; D013997:Time Factors; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology / Q000652:urine; D016482:Urinalysis
chemical_list: D000995:Antitubercular Agents; D004269:DNA, Bacterial
keywords: Antituberculosis drugs; Early bactericidal activity; Transrenal DNA; Treatment monitoring