title: Preparing Brain Slices to Study Basic Synaptic Properties.
abstract: This protocol describes how to prepare brain slices for electrophysiology, with an emphasis on synaptic physiology in voltage clamp. This approach remains the gold standard for understanding the properties of individual neurons, as well as the connections between neurons.
authors.affiliation: Department of Biological Sciences, University at Buffalo, State University of New York, Buffalo, New York 14260.
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Xu-Friedman
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D004594:Electrophysiology / Q000379:methods*; D009924:Organ Culture Techniques / Q000379:methods*; D018408:Patch-Clamp Techniques / Q000379:methods*; D012377:Rodentia; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission