title: OPTN/SRTR 2015 Annual Data Report: Intestine.
abstract: Intestine and intestine-liver transplant remains important in the treatment of intestinal failure, despite decreased morbidity associated with parenteral nutrition. In 2015, 196 new patients were added to the intestine transplant waiting list, with equal numbers waiting for intestine and intestine-liver transplant. Among prevalent patients on the list at the end of 2015, 63.3% were waiting for an intestine transplant and 36.7% were waiting for an intestine-liver transplant. The pretransplant mortality rate decreased dramatically over time for all age groups. Pretransplant mortality was notably higher for intestine-liver than for intestine transplant candidates (respectively, 19.9 vs. 2.8 deaths per 100 waitlist years in 2014-2015). By age, pretransplant mortality was highest for adult candidates, at 19.6 per 100 waitlist years, and lowest for children aged younger than 6 years, at 3.6 per 100 waitlist years. Pretransplant mortality by etiology was highest for candidates with non-congenital types of short-gut syndrome. Numbers of intestine transplants without a liver increased from a low of 51 in 2013 to 70 in 2015. Intestine-liver transplants increased from a low of 44 in 2012 to 71 in 2015. Short-gut syndrome (congenital and non-congenital) was the main cause of disease leading to intestine and to intestine-liver transplant. Patient survival was lowest for adult intestine-liver recipients and highest for pediatric intestine recipients.
authors.affiliation: Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.|Department of Pediatrics, University of Washington, Seattle, WA.
authors.forename: J M
authors.initials: JM
authors.lastname: Smith
authors.affiliation: Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.
authors.forename: M A
authors.initials: MA
authors.lastname: Skeans
authors.affiliation: Liver and Intestine Transplantation Program, Seattle Childrens Hospital, Seattle, WA.
authors.forename: S P
authors.initials: SP
authors.lastname: Horslen
authors.affiliation: Organ Procurement and Transplantation Network, Richmond, VA.|United Network for Organ Sharing, Richmond, VA.
authors.forename: E B
authors.initials: EB
authors.lastname: Edwards
authors.affiliation: Organ Procurement and Transplantation Network, Richmond, VA.|United Network for Organ Sharing, Richmond, VA.
authors.forename: A M
authors.initials: AM
authors.lastname: Harper
authors.affiliation: Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.|Department of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN.
authors.forename: J J
authors.initials: JJ
authors.lastname: Snyder
authors.affiliation: Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.|Department of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN.|Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN.
authors.forename: A K
authors.initials: AK
authors.lastname: Israni
authors.affiliation: Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.|Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN.
authors.forename: B L
authors.initials: BL
authors.lastname: Kasiske
mesh_terms: D000847:Annual Reports as Topic; D006085:Graft Survival; D006801:Humans; D007166:Immunosuppressive Agents; D007422:Intestines / Q000637:transplantation*; D040841:Resource Allocation; D014019:Tissue Donors / Q000600:supply & distribution*; D009927:Tissue and Organ Procurement / Q000379:methods*; D016896:Treatment Outcome; D014481:United States; D014850:Waiting Lists
chemical_list: D007166:Immunosuppressive Agents
keywords: Intestinal failure; intestine transplant; intestine-liver transplant; waiting list