title: Neurological Complications Resulting from Non-Oral Occupational Methanol Poisoning.
abstract: Methanol poisoning results in neurological complications including visual disturbances, bilateral putaminal hemorrhagic necrosis, parkinsonism, cerebral edema, coma, or seizures. Almost all reported cases of methanol poisoning are caused by oral ingestion of methanol. However, recently there was an outbreak of methanol poisoning via non-oral exposure that resulted in severe neurological complications to a few workers at industrial sites in Korea. We present 3 patients who had severe neurological complications resulting from non-oral occupational methanol poisoning. Even though initial metabolic acidosis and mental changes were improved with hemodialysis, all of the 3 patients presented optic atrophy and ataxia or parkinsonism as neurological complications resulting from methanol poisoning. In order to manage it adequately, as well as to prevent it, physicians should recognize that methanol poisoning by non-oral exposure can cause neurologic complications.
authors.affiliation: Department of Neurology, Ewha Womans University School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.
authors.forename: Ji Hyun
authors.identifier: http://orcid.org/0000-0003-2310-1368
authors.initials: JH
authors.lastname: Choi
authors.affiliation: Department of Neurology, Soonchunhyang University School of Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
authors.forename: Seung Keun
authors.initials: SK
authors.lastname: Lee
authors.affiliation: Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea.
authors.forename: Young Eun
authors.initials: YE
authors.lastname: Gil
authors.affiliation: Department of Occupational and Environmental Medicine, Ewha Womans University School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.
authors.forename: Jia
authors.identifier: http://orcid.org/0000-0002-7745-564X
authors.initials: J
authors.lastname: Ryu
authors.affiliation: Department of Occupational and Environmental Medicine, Ewha Womans University School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.
authors.forename: Kyunghee
authors.identifier: http://orcid.org/0000-0002-9800-0994
authors.initials: K
authors.lastname: Jung-Choi
authors.affiliation: Department of Occupational and Environmental Medicine, Ewha Womans University School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.
authors.forename: Hyunjoo
authors.initials: H
authors.lastname: Kim
authors.affiliation: Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea.
authors.forename: Jun Young
authors.initials: JY
authors.lastname: Choi
authors.affiliation: Department of Neurology, Soonchunhyang University School of Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
authors.forename: Sun Ah
authors.identifier: http://orcid.org/0000-0002-3027-3259
authors.initials: SA
authors.lastname: Park
authors.affiliation: Department of Neurology, Ewha Womans University School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.
authors.forename: Hyang Woon
authors.identifier: http://orcid.org/0000-0002-0610-085X
authors.initials: HW
authors.lastname: Lee
authors.affiliation: Department of Neurology, Ewha Womans University School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea. dream-yoon@hanmail.net.
authors.forename: Ji Young
authors.identifier: http://orcid.org/0000-0001-9648-9450
authors.initials: JY
authors.lastname: Yun
mesh_terms: D000138:Acidosis / Q000175:diagnosis / Q000209:etiology; D000328:Adult; D001259:Ataxia / Q000175:diagnosis* / Q000209:etiology; D001921:Brain / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D000432:Methanol / Q000506:poisoning*; D016273:Occupational Exposure; D009896:Optic Atrophy / Q000175:diagnosis* / Q000209:etiology; D020734:Parkinsonian Disorders / Q000175:diagnosis* / Q000209:etiology; D056910:Republic of Korea; D041623:Tomography, Optical Coherence
chemical_list: D000432:Methanol
keywords: Metabolic Encephalopathies; Methanol; Neurological Manifestations; Poisoning