title: [Evidence-based recommendations for diagnostics and treatment of gouty arthritis in the specialist sector : S2e guidelines of the German Society of Rheumatology in cooperation with the AWMF].
abstract: Due to the increasing prevalence of gout, particularly in old age, the disease is becoming of increasing importance in Germany. Gout is one of the most common forms of recurrent inflammatory arthritis and is induced by the deposition of monosodium urate crystals in synovial fluid and other tissues. The principal goals of therapy in chronic gout are the symptomatic treatment of the acute joint inflammation and the causal treatment of the underlying metabolic cause, the hyperuricemia. Only a consistent and permanent reduction of the serum uric acid level ultimately results in an efficient avoidance of further gout attacks and therefore the prevention of structural damage. Due to an often inadequate treatment of gout, the target of healing the disease is often not achieved. A correct and timely diagnosis and adequate assessment of comorbidities associated with gout are, however, of substantial importance for patient and physician to achieve remission of the disease. In order to create a solid basis for a timely and effective treatment of affected patients, in 2016 the German Society of Rheumatology (DGRh) initiated the development of S2e guidelines on gouty arthritis for specialists. This article summarizes these S2e guidelines on the management of gouty arthritis in the specialist sector.
authors.affiliation: Rheumazentrum Ruhrgebiet, Claudiusstr. 45, 44649, Herne, Deutschland. Uta.kiltz@elisabethgruppe.de.
authors.forename: U
authors.initials: U
authors.lastname: Kiltz
authors.affiliation: Rheumatologie, Klinische Immunologie, Osteologie, Physikalische Therapie und Sportmedizin, Schlosspark-Klinik, Berlin, Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Alten
authors.affiliation: Klinik und Poliklinik für Innere Medizin I, Klinik für Rheumatologie/Klinische Immunologie, Asklepios-Klinikum, Uniklinikum Regensburg, Bad Abbach, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Fleck
authors.affiliation: Rheumatologisches Praxiszentrum St. Bonifatius, München, Deutschland.
authors.forename: K
authors.initials: K
authors.lastname: Krüger
authors.affiliation: Medizinische Klinik 3, Universitätsklinikum Erlangen, Erlangen, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Manger
authors.affiliation: Abteilung für Rheumatologie und Klinische Immunologie, Kerckhoff-Klinik, Bad Nauheim, Deutschland.
authors.forename: U
authors.initials: U
authors.lastname: Müller-Ladner
authors.affiliation: Rheumatologische Schwerpunktpraxis, Nürnberg, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Nüsslein
authors.affiliation: Facharzt-Praxis für Rheumatologie und Onkologie, Bad Bocklet, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Reuss-Borst
authors.affiliation: Rheumatologisch-immunologische Ambulanz, Universitätsklinik Mainz, Mainz, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Schwarting
authors.affiliation: Klinikum der Universität München, München, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Schulze-Koops
authors.affiliation: Medizinische Klinik III, Abteilung für Rheumatologie, Universitätsklinikum Carl Gustav Carus, Dresden, Deutschland.
authors.forename: A K
authors.initials: AK
authors.lastname: Tausche
authors.affiliation: Rheumazentrum Ruhrgebiet, Claudiusstr. 45, 44649, Herne, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Braun
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D015210:Arthritis, Gouty / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D000066491:Clinical Decision-Making / Q000379:methods; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine / Q000592:standards; D005858:Germany; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D033461:Hyperuricemia / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D017063:Outcome Assessment, Health Care / Q000592:standards; D017410:Practice Guidelines as Topic; D012219:Rheumatology / Q000592:standards*; D016896:Treatment Outcome; D014528:Uricosuric Agents / Q000627:therapeutic use
chemical_list: D018501:Antirheumatic Agents; D006074:Gout Suppressants; D014528:Uricosuric Agents
keywords: Guidelines; Hyperuricemia; Inflammation; Joint; Management