title: Effects of carbomer eye drops in combination with orthokeratology lens in treating adolescent myopia.
abstract: To investigate the effects of carbomer eye drops (CED) during long-time wearing of overnight orthokeratology lens of adolescents with myopia, 260 teenagers with myopia treated in the Henan Provincial Peoples Hospital from June 2012 to August 2014 and followed-up for more than 2 years were enrolled. All the patients underwent regular fitting of orthokeratology lens. They were divided into a CED (Vidisic) group (130 cases, 260 eyes treated with CED) and rewetting drops (RD) (Baushe and Lomb) group (130 cases, 260 eyes treated with RD). The effects in the two groups were observed. The incidence of corneal epithelial defects one day, one week and one month after treatment of the CED group was lower than that of the RD group, and the difference was statistically significant (P less than 0.05); the tear break up time (TBUT) of the CED group was higher than that of the RD group at different time points, and the difference had statistical significance (P less than 0.05); the difference of the value of Schirmer I test between the two groups had no statistical significance (P>0.05). It is concluded that carbomer eye drops can stabilize tear film and protect and repair corneal epithelium during the wearing of orthokeratology lens.
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Shi
authors.affiliation: Teaching and Research Section of Optometry, Department of Medical Technology, Zhengzhou Railway Vocational and Technical College, Zhengzhou, China.
authors.forename: L T
authors.initials: LT
authors.lastname: Zhou
authors.affiliation: Department of Ophthalmology, Kaifeng Central Hospital, Kaifeng, China.
authors.forename: C X
authors.initials: CX
authors.lastname: Zhang
authors.affiliation: Luoyang Boai Ophthalmology Hospital, Luoyang, China.
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Li
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: J Z
authors.initials: JZ
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: H M
authors.initials: HM
authors.lastname: Zhou
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: Y G
authors.initials: YG
authors.lastname: Li
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: T
authors.initials: T
authors.lastname: Liu
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: L L
authors.initials: LL
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: L N
authors.initials: LN
authors.lastname: Sun
authors.affiliation: Department of Ophthalmology, Henan Provincial Peoples Hospital, Zhengzhou, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000180:Acrylic Resins / Q000008:administration & dosage*; D000293:Adolescent; D002648:Child; D003131:Combined Modality Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009216:Myopia / Q000628:therapy*; D009883:Ophthalmic Solutions; D054158:Orthokeratologic Procedures / Q000379:methods*; D055815:Young Adult
chemical_list: D000180:Acrylic Resins; D009883:Ophthalmic Solutions; C479038:carbomer