title: Oral phaeohyphomycosis in a patient with squamocellular carcinoma of the lip: second case report.
abstract: This communication reports the second known case of oral phaeohyphomycosis in a patient with squamocellular carcinoma of the lip. The patient, an 82-year-old black woman, a former smoker (for more than 30 years), suffering from an ulcerous vegetative lesion in the middle third of the lower lip for approximately 12 months. The result of the histopathological analysis indicated carcinoma, with well-differentiated keratinized squamous cells and the presence of septate mycelial filaments. In the direct mycological examination, thick and dematiaceous septate mycelial filaments were observed. After the resection surgery, the patient did not need to use an antifungal drug to treat the phaeohyphomycosis, and no follow-up radiotherapy was needed to treat the squamocellular carcinoma. We stress that the presence of the squamocellular lesion of the lip was a possible contributing factor to the infection.
authors.affiliation: Universidade Estadual do Amazonas, Departamento de Micologia, Manaus, Amazonas, Brasil.
authors.forename: Suanni Lemos de
authors.initials: SL
authors.lastname: Andrade
authors.affiliation: Universidade Federal de Pernambuco, Departamento de Micologia, Recife, Pernambuco, Brasil. Electronic address: andreferrazleal@yahoo.com.br.
authors.forename: André Ferraz Goiana
authors.initials: AFG
authors.lastname: Leal
authors.affiliation: Universidade Federal de Pernambuco, Departamento de Micologia, Recife, Pernambuco, Brasil.
authors.forename: Armando Marsden Lacerda
authors.initials: AML
authors.lastname: Filho
authors.affiliation: Universidade Federal de Pernambuco, Departamento de Micologia, Recife, Pernambuco, Brasil.
authors.forename: Danielle Patrícia Cerqueira
authors.initials: DPC
authors.lastname: Macêdo
authors.affiliation: Universidade Federal de Pernambuco, Departamento de Patologia, Recife, Pernambuco, Brasil.
authors.forename: Maria do Carmo Carvalho de
authors.initials: MDCC
authors.lastname: Abreu E Lima
authors.affiliation: Universidade Federal de Pernambuco, Departamento de Micologia, Recife, Pernambuco, Brasil.
authors.forename: Rejane Pereira
authors.initials: RP
authors.lastname: Neves
mesh_terms: D000369:Aged, 80 and over; D001938:Brazil; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000601:surgery; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008046:Lip / Q000473:pathology* / Q000601:surgery; D008048:Lip Neoplasms / Q000150:complications* / Q000601:surgery; D008828:Microbiological Techniques; D008853:Microscopy; D060446:Phaeohyphomycosis / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
keywords: Lip; Oral phaeohyphomycosis; Squamocellular carcinoma