title: [Thrombolysis in stroke mimics: Experience in 10 cases].
abstract: BACKGROUND
  The effectiveness of intravenous thrombolysis (IVT) in cerebral ischemia is time dependent. Stroke mimics (SM) are frequent in emergency rooms. The effort to reduce door to needle time, can lead to administer thrombolytics to SM.
  
  
  OBJECTIVE
  To describe the frequency and prognosis of SM treated with IVT.
  
  
  METHODS
  Prospective analysis of all patients evaluated in a Chilean private clinic between December 2004 and July 2015 with a suspected acute ischemic stroke (AIS). We calculated the number of SM that were treated with IVT. In these patients, we analyzed the presence of symptomatic cerebral hemorrhage defined as the presence of a neurological deterioration of four points or more on the National Institute of Health Stroke Scale, the presence of extracranial bleeding according to Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries criteria and the patient's functional status at three months by modified Rankin scale (MRS).
  
  
  RESULTS
  We evaluated 1,417 patients with suspected AIS, of which 240 (16.9%) were finally diagnosed as SM. A total of 197 patients were treated with IVT, of these 10 (5%) corresponded to SM. All SM patients treated with thrombolytic drugs were functionally independent at 3 months and showed no bleeding complications.
  
  
  CONCLUSIONS
  Occasionally SM patients were treated with IVT. This treatment was not associated with bleeding complications and the prognosis of these patients at three months was favorable.
authors.affiliation: Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
authors.forename: Alejandro M
authors.initials: AM
authors.lastname: Brunser
authors.affiliation: Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
authors.forename: Arnold
authors.initials: A
authors.lastname: Hoppe
authors.affiliation: Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
authors.forename: Paula
authors.initials: P
authors.lastname: Muñoz
authors.affiliation: Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
authors.forename: Pablo M
authors.initials: PM
authors.lastname: Lavados
authors.affiliation: Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
authors.forename: Sergio
authors.initials: S
authors.lastname: Illanes
authors.affiliation: Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
authors.forename: Violeta
authors.initials: V
authors.lastname: Díaz
authors.affiliation: Unidad de Tratamiento del Ataque Cerebrovascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Santiago, Chile.
authors.forename: Verónica V
authors.initials: VV
authors.lastname: Olavarría
mesh_terms: D061605:Administration, Intravenous; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications / Q000188:drug therapy*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D020521:Stroke / Q000150:complications / Q000188:drug therapy*; D062606:Tertiary Care Centers; D015912:Thrombolytic Therapy; D013997:Time Factors; D061665:Time-to-Treatment
chemical_list: D005343:Fibrinolytic Agents