title: The use of negative pressure wound therapy in the treatment of infected wounds. Case studies.
abstract: OBJECTIVE
  To evaluate the results and benefits obtained from the topical use of negative pressure wound therapy (NPWT) in patients with infected wounds.
  
  
  METHODS
  This was a retrospective study of 20 patients (17 males and three females, mean age 42 years) with infected wounds treated using NPWT. The infected wounds were caused by trauma. The treatment system used was VAC.®(Vacuum Assisted Closure, KCI, San Antonio, United States) applied to the wound in continuous mode from 100 to 125 mmHg. The parameters related to the wounds (location, number of VAC changes, the size of the defects in the soft parts, and the evolution of the state of the wound), length of hospital stay, length of intravenous antibiotic therapy, and complications related to the use of this therapy were evaluated.
  
  
  RESULTS
  The mean length of the hospital stay, use of NPWT, and antibacterial therapy were 41 days, 22.5 days, and 20 days respectively. The use of the VAC led to a mean reduction of 29% in the wound area (95.65-68.1 cm2;p< 0.05). Only one patient did not show any improvement in the final appearance of the wound with complete eradication of the infection. No complication directly caused by NPWT was observed.
  
  
  CONCLUSIONS
  NPWT stimulates infection-free scar tissue formation in a short time, and is a quick and comfortable alternative to conventional infected wounds treatment methods.
authors.affiliation: Hospital São Rafael, Serviço de Ortopedia e Traumatologia, Salvador, BA, Brazil.
authors.forename: Daniel de Alcântara
authors.initials: DA
authors.lastname: Jones
authors.affiliation: Hospital São Rafael, Serviço de Ortopedia e Traumatologia, Salvador, BA, Brazil.
authors.forename: Wilson Vasconcelos
authors.initials: WV
authors.lastname: Neves Filho
authors.affiliation: Hospital São Rafael, Serviço de Ortopedia e Traumatologia, Salvador, BA, Brazil.
authors.forename: Janice de Souza
authors.initials: JS
authors.lastname: Guimarães
authors.affiliation: Hospital São Rafael, Serviço de Ortopedia e Traumatologia, Salvador, BA, Brazil.
authors.forename: Daniel de Araújo
authors.initials: DA
authors.lastname: Castro
authors.affiliation: Hospital São Rafael, Serviço de Ortopedia e Traumatologia, Salvador, BA, Brazil.
authors.forename: Antonio Marcos
authors.initials: AM
authors.lastname: Ferracini
keywords: Infection; Negative-pressure wound therapy; Wound healing; Wounds and injuries