title: Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature.
abstract: Introduction.Angiomyolipomas are the most common benign tumor of the kidney, associated with Tuberous Sclerosis in 20% of cases and arising sporadically in 80% of cases. Renal angiomyolipomas are neoplasms of mesenchymal origin with varying proportions of vasculature, smooth muscle spindle cells, and adipocytes, making management of such neoplasms a challenging endeavor. Possible management options include partial or radical nephrectomy and segmental renal artery embolization.Case Presentation.A 61-year-old woman admitted for a large retroperitoneal hemorrhage was discovered to have a giant, sporadic, 3818.3 g, 30.0 × 26.5 × 18.0 cm left perinephric angiomyolipoma. Given her hemodynamic instability upon presentation, she underwent segmental arterial embolization, followed by an open left partial nephrectomy. Ten-month follow-up revealed no noticeable loss of renal function.Discussion.Literature review revealed occasional renal angiomyolipomas of comparable size, with all angiomyolipomas larger than this requiring treatment with radical nephrectomy.Conclusion.We show that nephron-sparing surgery may be considered in the treatment of even the largest of renal angiomyolipomas.
authors.affiliation: University of Minnesota Medical School, Minneapolis, MN, USA.
authors.forename: Jacob
authors.identifier: 0000-0003-4546-9948
authors.initials: J
authors.lastname: Albersheim-Carter
authors.affiliation: University of Minnesota Medical School, Minneapolis, MN, USA.
authors.forename: Molly
authors.initials: M
authors.lastname: Klein
authors.affiliation: University of Minnesota Medical School, Minneapolis, MN, USA.
authors.forename: Paari
authors.initials: P
authors.lastname: Murugan
authors.affiliation: University of Minnesota Medical School, Minneapolis, MN, USA.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Weight