title: [Nuclear medicine techniques for selective internal radiotherapy of liver cancer].
abstract: Selective internal radiation therapy (SIRT) of hepatocellular carcinoma has been introduced at Aarhus University Hospital. 90Y-microspheres are implanted in the tumour by catheterization of the tumour feeding liver artery. Pretreatment angiography and test treatment using 99mTc-labelled particles followed by scintigraphy ensure a feasible and effective treatment. Post-treatment imaging of radiation from 90Y visualize the localization of microspheres. Currently, SIRT is also applied for liver metastases of neuroendocrine tumours. Future indications may include other liver tumours and metastases.
authors.affiliation: gerdvill@rm.dk.
authors.forename: Peter Frøhlich
authors.initials: PF
authors.lastname: Staanum
authors.forename: Anne Kirstine
authors.initials: AK
authors.lastname: Arveschoug
authors.forename: Stine Maria Jentoft
authors.initials: SM
authors.lastname: Kramer
authors.forename: Jens Erik
authors.initials: JE
authors.lastname: Nielsen
authors.forename: Dennis Tønner
authors.initials: DT
authors.lastname: Nielsen
authors.forename: Peter
authors.initials: P
authors.lastname: Ott
authors.forename: Henning
authors.initials: H
authors.lastname: Grønbæk
authors.forename: Gerda Elisabeth
authors.initials: GE
authors.lastname: Villadsen
mesh_terms: D000792:Angiography; D006528:Carcinoma, Hepatocellular / Q000532:radiotherapy; D004621:Embolization, Therapeutic / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D008863:Microspheres; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000627:therapeutic use*; D013668:Technetium Tc 99m Aggregated Albumin; D015899:Tomography, Emission-Computed, Single-Photon; D015021:Yttrium Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D015021:Yttrium Radioisotopes; C000615496:Yttrium-90