title: Grape Polyphenols' Effects in Human Cardiovascular Diseases and Diabetes.
abstract: The consumption of fruits and vegetables, as well as foods enriched in bioactive compounds and nutraceuticals, has increased due to consumers' interest in the relevance of food composition for human health. Considerable recent interest has focused on bioactive phenolic compounds in grape, as they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, anti-ageing and antimicrobial properties. Observational studies indicate that the intake of polyphenol-rich foods improves vascular health, thereby significantly reducing the risk of hypertension, and cardiovascular disease (CVD). Other researchers have described the benefits of a grape polyphenol-rich diet for other types of maladies such as diabetes mellitus. This is a comprehensive review on the consumption of polyphenolic grape compounds, concerning their potential benefits for human health in the treatment of cardiovascular diseases and diabetes.
authors.affiliation: Université de Bordeaux, ISVV, Institut des Sciences de la Vigne et du Vin, EA 4577 Œnologie, 210 Chemin de Leysotte, Villenave d'Ornon F-33140, France. zrasines@hotmail.es.|INRA, Instiut National de la Recherche Agronomique, ISVV, Institut des Sciences de la Vigne et du Vin, USC 1366 Œnologie, 210 Chemin de Leysotte, Villenave d'Ornon F-33140, France. zrasines@hotmail.es.
authors.forename: Zuriñe
authors.initials: Z
authors.lastname: Rasines-Perea
authors.affiliation: Université de Bordeaux, ISVV, Institut des Sciences de la Vigne et du Vin, EA 4577 Œnologie, 210 Chemin de Leysotte, Villenave d'Ornon F-33140, France. p.teissedre@u-bordeaux2.fr.|INRA, Instiut National de la Recherche Agronomique, ISVV, Institut des Sciences de la Vigne et du Vin, USC 1366 Œnologie, 210 Chemin de Leysotte, Villenave d'Ornon F-33140, France. p.teissedre@u-bordeaux2.fr.
authors.forename: Pierre-Louis
authors.initials: PL
authors.lastname: Teissedre
mesh_terms: D002318:Cardiovascular Diseases / Q000178:diet therapy* / Q000473:pathology; D003920:Diabetes Mellitus / Q000178:diet therapy* / Q000473:pathology; D005638:Fruit / Q000737:chemistry; D006801:Humans; D059808:Polyphenols / Q000737:chemistry / Q000627:therapeutic use*; D012307:Risk Factors; D027843:Vitis / Q000737:chemistry; D014920:Wine
chemical_list: D059808:Polyphenols
keywords: cardiovascular diseases; dietary antioxidant; grape polyphenols; type 2 diabetes