title: Iron Overload in the Liver of 2 Children: Nonalcoholic Steatohepatitis and Juvenile Hemochromatosis.
abstract: Iron overload disorders are hereditary hemochromatosis and secondary etiologies other than hereditary hemochromatosis. We describe 2 boys presenting with iron overload. Juvenile hemochromatosis and nonalcoholic steatohepatitis (NASH) related iron overload are the genetic and secondary causes, respectively.
  
  
  
  Both patients benefited from phlebotomy even if they had different etiologies.
  
  
  
  In childhood, the diagnosis of iron overload syndromes is crucial because they do not confront us with obvious symptoms and findings. Early initiation of a phlebotomy program can prevent mortality. NASH might lead to iron overload and iron overload might aggravate the clinical course of NASH.
authors.affiliation: Departments of *Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition ‡Pathology, Gazi University Faculty of Medicine, Ankara, Turkey †"Mario Coppo" Liver Research Center, Division of Internal Medicine 2 and Center for Hemochromatosis, University Hospital of Modena, Modena, Italy.
authors.forename: Aysel
authors.initials: A
authors.lastname: Ünlüsoy Aksu
authors.forename: Angela
authors.initials: A
authors.lastname: Caleffi
authors.forename: Antonello
authors.initials: A
authors.lastname: Pietrangelo
authors.forename: Sinan
authors.initials: S
authors.lastname: Sari
authors.forename: Ödül
authors.initials: Ö
authors.lastname: Eğritaş Gürkan
authors.forename: Zeliha
authors.initials: Z
authors.lastname: Demirtaş
authors.forename: Güldal
authors.initials: G
authors.lastname: Yilmaz
authors.forename: Buket
authors.initials: B
authors.lastname: Dalgiç
mesh_terms: D000293:Adolescent; D006432:Hemochromatosis / Q000150:complications / Q000151:congenital*; D006801:Humans; D019190:Iron Overload / Q000150:complications* / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D008099:Liver / Q000473:pathology; D008297:Male; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications*; D018962:Phlebotomy