title: Rethinking the Claisen-Tishchenko Reaction.
abstract: Pincer-type complexes [OsH2(CO){PyCH2NHCH2CH2NHPtBu2}] and [OsH2(CO){HN(CH2CH2PiPr2)2}] catalyze the disproportionation reaction of aldehydes via an outer-sphere bifunctional mechanism achieving turnover frequencies up to 14 000 h-1. The N-H group of the catalysts is a key player in this process, elucidated with the help of DFT calculations.
authors.affiliation: Department of Chemistry and Biochemistry, Wilfrid Laurier University, 75 University Ave. W., Waterloo, ON, N2L 3C5, Canada.
authors.forename: Stacey A
authors.initials: SA
authors.lastname: Morris
authors.affiliation: Department of Chemistry and Biochemistry, Wilfrid Laurier University, 75 University Ave. W., Waterloo, ON, N2L 3C5, Canada.
authors.forename: Dmitry G
authors.identifier: 0000-0003-3302-356X
authors.initials: DG
authors.lastname: Gusev
keywords: aldehyde disproportionation; bifunctional catalysts; ester synthesis; metal-ligand cooperation; pincer complexes