title: Dramatic response in the dependency to transfusion after low doses of lenalidomide treatment in a 5q-syndrome patient: a case report.
abstract: 5q-syndrome is a special subgroup of myelodysplastic syndrome in terms of follow-up and treatment. Lenalidomide is an immunomodulatory drug that is frequently used in the treatment of multiple myeloma. Some clinical studies have shown that lenalidomide treatment is effective in 5q syndrome and significantly decreases the transfusion dependency in these patients. In this paper, we would like to share a dramatic response of lowered transfusion dependency after treatment with low-dose lenalidomide in a patient who received myelodysplastic syndrome diagnosis and isolated 5q anomaly in our clinic.
authors.affiliation: Department of Hematology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
authors.forename: Mehmet Hilmi
authors.initials: MH
authors.lastname: Dogu
authors.affiliation: Department of Hematology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Sari
authors.affiliation: Department of Hematology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Hacioglu
authors.affiliation: Department of Hematology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Keskin
keywords: Lenalidomide; del(5q); myelodysplastic syndrome