title: [Diagnosis of pulmonary hemorrhage of the newborn infants using lung ultrasonography].
abstract: Objective:To investigate the accuracy and reliability of lung ultrasound in diagnosis of pulmonary hemorrhage of the newborn infants.Method:From January 2014 to May 2016, 142 neonates from the Army General Hospital of the Chinese PLA were enrolled in the study. They were divided into two groups: a study group of 42 neonates, who were diagnosed with pulmonary hemorrhage according to their medical history, clinical manifestations and chest X-ray findings, and a control group of 100 neonates with no lung disease. All subjects underwent bedside lung ultrasound in a quiet state in a supine, lateral or prone posture, performed by a single experienced physician. The ultrasound findings were compared between the two groups.Fisher's exact test was uesd for comparison between two groups.Result:The lung ultrasound main findings associated with pulmonary hemorrhage included: (1) Shred sign: which was seen in 40 patients(95%). (2) Lung consolidation with air bronchograms: which were seen in 35 patients(83%). (3) Pleural effusion: which was seen in 34 infants(81%), pleurocentesis confirmed that the fluid was really bleeding.(4)Atelectasis: which was seen in 14 cases(33%). (5) Pleural line abnormalities and disappearing A-lines with an incidence of 100%. (6) Alveolar-interstitial syndrome: 5 patients(12%)had the main manifestations of alveolar-interstitial syndrome. The above signs were not seen in normal controls (allP<0.01) and the normal lung mainly manifested with clear pleural line and A-lines under ultrasound.Conclusion:Lung ultrasonography is accurate and reliable for diagnosing pulmonary hemorrhage, which is suitable for routine application for the diagnosis of pulmonary hemorrhage in the neonatal intensive care unit.
authors.affiliation: Department of Neonatology and Neonatal Intensive Care Unit of Bayi Children's Hospital, the Army General Hospital of the Chinese PLA, Beijing 100700, China.
authors.forename: J
authors.initials: J
authors.lastname: Liu
authors.forename: W
authors.initials: W
authors.lastname: Fu
authors.forename: S W
authors.initials: SW
authors.lastname: Chen
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
mesh_terms: D005260:Female; D006470:Hemorrhage / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008168:Lung; D008171:Lung Diseases / Q000175:diagnosis*; D008297:Male; D010994:Pleura; D010996:Pleural Effusion; D001261:Pulmonary Atelectasis / Q000175:diagnosis*; D013902:Radiography, Thoracic; D015203:Reproducibility of Results; D014463:Ultrasonography