title: Effect of Protein Corona on Silver Nanoparticle Stabilization and Ion Release Kinetics in Artificial Seawater.
abstract: In parallel with the growing use of nanoparticle-containing products, their release into the environment over the coming years is expected to increase significantly. With many large population centers located in near-coastal areas, and increasing evidence that various nanoparticles may be toxic to a range of organisms, biota in estuarine and coastal waters may be particularly vulnerable. While size effects may be important in cases, silver nanoparticles have been found to be toxic in large part due to their release of silver ions. However, there is relatively little data available on how nanoparticle coatings can affect silver ion release in estuarine or marine waters. We have found that albumin, as a model for biocorona-forming macromolecules which nanoparticles may encounter in wastewater streams, stabilizes silver colloids from agglomeration in high salinity marine waters by electrosteric repulsion for long time periods. A minimum mass ratio of about 130 for albumin:silver nanoparticles (40 nm) was required for stable dispersion in seawater. Increasing albumin concentration was also found to reduce dissolution of nanoparticles in seawater with up to 3.3 times lower concentrations of silver ions noted. Persistent colloids and slow sustained ion release may have important consequences for biota in these environmental compartments.
authors.affiliation: Ruđer Bošković Institute , Center for Marine Research, G. Paliaga 5, 52210 Rovinj, Croatia.
authors.forename: Maja
authors.initials: M
authors.lastname: Levak
authors.affiliation: Ruđer Bošković Institute , Center for Marine Research, G. Paliaga 5, 52210 Rovinj, Croatia.
authors.forename: Petra
authors.initials: P
authors.lastname: Burić
authors.affiliation: Ruđer Bošković Institute , Division of Physical Chemistry, Bijenička cesta 54, 10000 Zagreb, Croatia.
authors.forename: Maja
authors.identifier: 0000-0001-6230-5190
authors.initials: M
authors.lastname: Dutour Sikirić
authors.affiliation: Ruđer Bošković Institute , Division of Physical Chemistry, Bijenička cesta 54, 10000 Zagreb, Croatia.
authors.forename: Darija
authors.identifier: 0000-0001-5261-5961
authors.initials: D
authors.lastname: Domazet Jurašin
authors.affiliation: Ruđer Bošković Institute , Division of Marine and Environmental Research, Bijenička cesta 54, 10000 Zagreb, Croatia.
authors.forename: Nevenka
authors.initials: N
authors.lastname: Mikac
authors.affiliation: Ruđer Bošković Institute , Division of Marine and Environmental Research, Bijenička cesta 54, 10000 Zagreb, Croatia.
authors.forename: Niko
authors.initials: N
authors.lastname: Bačić
authors.affiliation: Postnova Analytics GmbH, Max-Planck-Straße 14, 86899 Landsberg am Lech, Germany.
authors.forename: Roland
authors.initials: R
authors.lastname: Drexel
authors.affiliation: Postnova Analytics GmbH, Max-Planck-Straße 14, 86899 Landsberg am Lech, Germany.
authors.forename: Florian
authors.initials: F
authors.lastname: Meier
authors.affiliation: Ruđer Bošković Institute , Center for Marine Research, G. Paliaga 5, 52210 Rovinj, Croatia.
authors.forename: Željko
authors.initials: Ž
authors.lastname: Jakšić
authors.affiliation: Ruđer Bošković Institute , Center for Marine Research, G. Paliaga 5, 52210 Rovinj, Croatia.
authors.forename: Daniel M
authors.identifier: 0000-0001-7669-2136
authors.initials: DM
authors.lastname: Lyons
mesh_terms: D007700:Kinetics; D053768:Metal Nanoparticles; D000066970:Protein Corona; D012623:Seawater; D012834:Silver; D014874:Water Pollutants, Chemical / Q000633:toxicity
chemical_list: D000066970:Protein Corona; D014874:Water Pollutants, Chemical; D012834:Silver