title: Effects of 4-week continuous ingestion of champignon extract on halitosis and body and fecal odor.
abstract: This was placebo-controlled double-blind parallel-group comparative clinical trial targeting 80 men and women aged 50-79 years with halitosis and body and fecal odor. We investigated whether daily champignon extract ingestion for 4 weeks improved these conditions. Subjects were divided into four groups: a placebo group and 50, 500, and 1000 mg/day ingestion groups. No severe adverse events or side effects were noted during the study period. Compared with the placebo group, all champignon extract ingestion groups showed improvement or tendency toward improvement in halitosis and body and fecal odor. Furthermore, our results suggested that the effectiveness of champignon extract in alleviating odors is dose-dependent, i.e., it increases with the dosage.
authors.affiliation: Department of Medical Management and Informatics, Hokkaido Information University, Hokkaido, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Nishihira
authors.affiliation: Department of Medical Management and Informatics, Hokkaido Information University, Hokkaido, Japan.
authors.forename: Mie
authors.initials: M
authors.lastname: Nishimura
authors.affiliation: Department of Medical Management and Informatics, Hokkaido Information University, Hokkaido, Japan.
authors.forename: Aiko
authors.initials: A
authors.lastname: Tanaka
authors.affiliation: Primary Cell Division, Cosmo Bio Co., Ltd., Sapporo, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Yamaguchi
authors.affiliation: Primary Cell Division, Cosmo Bio Co., Ltd., Sapporo, Japan.
authors.forename: Toshio
authors.initials: T
authors.lastname: Taira
keywords: Champignon; Clinical trial; Fecal odor; Halitosis