title: The biodegradation of fullerene C60by myeloperoxidase.
abstract: It is shown for the first time that the mammalian enzymes can cause the degradation of the C60 fullerene molecules. This biodegradation is caused by the action of а hypochlorite generated neutrophil enzyme myeloperoxidase of fullerene molecule and leads to the loss of the topology of the fullerene core.
authors.affiliation: Institute of Experimental Medicine, ul. Akademika Pavlova 12, St. Petersburg, 197376, Russia. llitasova@mail.ru.
authors.forename: E V
authors.initials: EV
authors.lastname: Litasova
authors.affiliation: Institute of Experimental Medicine, ul. Akademika Pavlova 12, St. Petersburg, 197376, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Iljin
authors.affiliation: Institute of Experimental Medicine, ul. Akademika Pavlova 12, St. Petersburg, 197376, Russia.|St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Sokolov
authors.affiliation: Institute of Experimental Medicine, ul. Akademika Pavlova 12, St. Petersburg, 197376, Russia.|St. Petersburg State University, Universitetskaya nab. 7/9, St. Petersburg, 199034, Russia.
authors.forename: V B
authors.initials: VB
authors.lastname: Vasilyev
authors.affiliation: Institute of Experimental Medicine, ul. Akademika Pavlova 12, St. Petersburg, 197376, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Dumpis
authors.affiliation: Institute of Experimental Medicine, ul. Akademika Pavlova 12, St. Petersburg, 197376, Russia.
authors.forename: L B
authors.initials: LB
authors.lastname: Piotrovskiy
mesh_terms: D045744:Cell Line, Tumor; D002846:Chromatography, Affinity; D037741:Fullerenes / Q000737:chemistry*; D006801:Humans; D006861:Hydrogen Peroxide / Q000737:chemistry; D006997:Hypochlorous Acid / Q000737:chemistry; D009504:Neutrophils / Q000737:chemistry; D009195:Peroxidase / Q000737:chemistry* / Q000302:isolation & purification; D012996:Solutions; D013057:Spectrum Analysis; D013447:Sulfites / Q000737:chemistry
chemical_list: D037741:Fullerenes; D012996:Solutions; D013447:Sulfites; D006997:Hypochlorous Acid; D006861:Hydrogen Peroxide; D009195:Peroxidase; C069837:fullerene C60; C025026:sodium sulfite