title: Effects of smoking on healthy young men's hematologic parameters.
abstract: OBJECTIVE
  Cigarette smoking carries higher risks for most of the chronic diseases. It also has chronic and acute effects on the hematologic system. This study explores the effects of cigarette smoking on some blood values of the healthy young male smokers.
  
  
  METHODS
  In this study, cigarette smoking and usage of substance, additional diseases, birth places, and education levels of 171 healthy male subjects between the ages of 20 and 30 years were investigated. Anthropometric measurements of the cases were obtained. Thyroid function tests, vitamin B12, folic acid, ferritin, ferrous/ıron, total ıron binding capacity, leucocytes, platelets, hemoglobin, hematocrit, mean corpuscular volume (MCV), mean platelet volume (MPV), HBs AG, Anti-HBs and Anti-HIV were evaluated. Groups of smokers and nonsmokers were compared. The group of smokers was also sorted into subgroups of "2 year-smokers", "5 year-smokers" and "10 year-smokers" according to their pack-years of smoking. The effects of pack-years of smoking on the blood values were also investigated.
  
  
  RESULTS
  The MCV values of the group of smokers were higher than the values of nonsmokers, which were statistically significant (p<0.05). As a result of the subgroup analyses of smokers, the white blood cell (WBC) counts of the individuals smoking for 5 or more years were significantly higher than those with a history of smoking less than 5 years, (p<0.05).
  
  
  CONCLUSIONS
  This study supports the idea that cigarette smoking and especially longer durations of smoking have adverse effects on the hematologic parameters.
authors.affiliation: Department of Family Medicine, Pinarhisar State Hospital, Kirklareli, Turkey.
authors.forename: Besime
authors.initials: B
authors.lastname: Inal
authors.affiliation: Department of Hematology, Edirne State Hospital, Edirne, Turkey.
authors.forename: Tuba
authors.initials: T
authors.lastname: Hacıbekiroglu
authors.affiliation: Department of Internal Medicine, Pinarhisar State Hospital, Kırklareli, Turkey.
authors.forename: Bilger
authors.initials: B
authors.lastname: Cavus
authors.affiliation: Department of Family Medicine, Pinarhisar State Hospital, Kirklareli, Turkey.
authors.forename: Zeliha
authors.initials: Z
authors.lastname: Musaoglu
authors.affiliation: Department of Biochemistry, Kirklareli State Hospital, Kirklareli, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Demir
authors.affiliation: Department of Geriatrics, Acibadem University Faculty of Medicine, Istanbul, Turkey.
authors.forename: Berrin
authors.initials: B
authors.lastname: Karadag
keywords: Cigarette; hematologic parameters; young man