title: Lipid Profile of Children with Malaria byPlasmodium vivax.
abstract: Background. Changes in lipid profile are commonly reported in adult patients with malaria. However, a few studies evaluated lipid abnormalities in children continuously exposed toP. vivax.Objective. To evaluate lipid abnormalities in children withP. vivaxinfection and to assess if parasite count or the history of malaria correlates with lipid levels at admission.Methods. A total of 75 children were included in the study, from which 43 were slide confirmed infection byP. vivax. Serial blood samples were collected at admission and, on days 7 and 14, evaluated for the colorimetric measurements of triglycerides, very low-density lipoprotein (VLDL), total cholesterol, high-density lipoprotein (HDL), and low-density lipoprotein (LDL).Results. The levels of total cholesterol, LDL, and HDL were significantly lower in malaria cases. The levels of VLDL and triglycerides were significantly higher in children with malaria. Such changes were transient and were not associated with parasite counting as well as with the history of malaria of patients.Conclusion. There are significant lipid abnormalities in children with low level ofP. vivaxinfection and mild signs and symptoms of the disease, which are not associated with parasitaemia and previous episodes of disease.
authors.affiliation: Health Science Institute, Pará Federal University, Belém, PA, Brazil.
authors.forename: Rosa Maria
authors.initials: RM
authors.lastname: Dias
authors.affiliation: Health Science Institute, Pará Federal University, Belém, PA, Brazil.
authors.forename: Jose Luiz Fernandes
authors.identifier: 0000-0003-4842-8762
authors.initials: JL
authors.lastname: Vieira
authors.affiliation: Health Science Institute, Pará Federal University, Belém, PA, Brazil.
authors.forename: Bianca da Conceição
authors.initials: BD
authors.lastname: Cabral
authors.affiliation: Health Science Institute, Pará Federal University, Belém, PA, Brazil.
authors.forename: Isameriliam Rosaulem Pereira
authors.initials: IR
authors.lastname: da Silva
authors.affiliation: Health Science Institute, Pará Federal University, Belém, PA, Brazil.
authors.forename: Laelia Maria Barra Feio
authors.initials: LM
authors.lastname: Brasil
authors.affiliation: Health Science Institute, Pará Federal University, Belém, PA, Brazil.
authors.forename: Eliete da Cunha
authors.initials: ED
authors.lastname: Araújo
authors.affiliation: Health Science Institute, Pará Federal University, Belém, PA, Brazil.
authors.forename: Marcieni Ataíde
authors.initials: MA
authors.lastname: de Andrade