title: Prenatal diagnosis of pericallosal curvilinear lipoma: specific imaging pattern and diagnostic pitfalls.
abstract: We report the first series of cases of pericallosal curvilinear lipoma (CL) diagnosed prenatally and highlight the limitations in identifying a specific prenatal imaging pattern using ultrasound and magnetic resonance imaging (MRI). In all five of our cases, on ultrasound, the main feature leading to referral was a short corpus callosum. This subtle callosal dysgenesis was associated with a band of hyperechogenicity surrounding the corpus callosum, mimicking the pericallosal sulcus, which increased in size during the third trimester in three of the four cases in which sonographic follow-up was performed. On T2-weighted MRI, this band showed typical hypointensity in all cases; in contrast, on T1-weighted imaging, in only one case was there hyperintensity, suggestive of fat, as seen typically in the postnatal period. For appropriate prenatal counseling regarding outcome, it is important to identify or rule out CL when mild corpus callosal dysgenesis is observed. One should be aware of subtle diagnostic findings, such as a thin band of echogenicity surrounding the corpus callosum that is seen as a band of hypointensity on T2-weighted fetal MRI, and which may increase in size during gestation. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
authors.affiliation: Centre Pluridisciplinaire de Diagnostic Prénatal, Hôpital Femme Mère Enfant, Lyon Bron, France.
authors.forename: A
authors.initials: A
authors.lastname: Atallah
authors.affiliation: Imagerie Pédiatrique et Fœtale, Hôpital Femme Mère Enfant, Université Claude Bernard Lyon 1, Lyon Bron, France.
authors.forename: A
authors.initials: A
authors.lastname: Lacalm
authors.affiliation: Centre Pluridisciplinaire de Diagnostic Prénatal, Hôpital Femme Mère Enfant, Lyon Bron, France.
authors.forename: M
authors.initials: M
authors.lastname: Massoud
authors.affiliation: Centre Pluridisciplinaire de Diagnostic Prénatal, Hôpital Femme Mère Enfant, Lyon Bron, France.
authors.forename: J
authors.initials: J
authors.lastname: Massardier
authors.affiliation: Centre Pluridisciplinaire de Diagnostic Prénatal, Hôpital Femme Mère Enfant, Lyon Bron, France.
authors.forename: P
authors.initials: P
authors.lastname: Gaucherand
authors.affiliation: Centre Pluridisciplinaire de Diagnostic Prénatal, Hôpital Femme Mère Enfant, Lyon Bron, France.|Imagerie Pédiatrique et Fœtale, Hôpital Femme Mère Enfant, Université Claude Bernard Lyon 1, Lyon Bron, France.
authors.forename: L
authors.identifier: 0000-0002-5747-6654
authors.initials: L
authors.lastname: Guibaud
mesh_terms: D000328:Adult; D061085:Agenesis of Corpus Callosum / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D001932:Brain Neoplasms / Q000151:congenital / Q000000981:diagnostic imaging* / Q000196:embryology; D003337:Corpus Callosum / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007231:Infant, Newborn; D008067:Lipoma / Q000151:congenital / Q000000981:diagnostic imaging* / Q000196:embryology; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
keywords: CNS; MRI; corpus callosum; fetal; lipoma; ultrasound