title: Accessing alternative reaction pathways of the intermolecular condensation between homo-propargyl alcohols and terminal alkynes through divergent gold catalysis.
abstract: An intermolecular condensation of alkynols and terminal alkynes is reported. Using IPrAuNTf2, an efficient Au-catalyzed cyclization-alkynylation strategy furnishes (2-arylalkynyl) cyclic ethers in moderate to excellent yields (up to 94%). This strategy is extended to the synthesis of functionalized 2,3-dihydrooxepines via the sequential Au-catalyzed ring expansion of the cyclic ether substrates.
authors.affiliation: Department of Chemistry, University of South Florida, Tampa, FL 33620, USA. xmshi@usf.edu.
authors.forename: Courtney A
authors.initials: CA
authors.lastname: Smith
authors.affiliation: Department of Chemistry, University of South Florida, Tampa, FL 33620, USA. xmshi@usf.edu.
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Motika
authors.affiliation: Department of Chemistry, University of South Florida, Tampa, FL 33620, USA. xmshi@usf.edu.
authors.forename: Lukasz
authors.initials: L
authors.lastname: Wojtas
authors.affiliation: Department of Chemistry, University of South Florida, Tampa, FL 33620, USA. xmshi@usf.edu.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Shi