title: Parent-Reported Developmental Regression in Autism: Epilepsy, IQ, Schizophrenia Spectrum Symptoms, and Special Education.
abstract: Examined the psychiatric and clinical correlates of loss of previously acquired skills (regression) as reported by parents of youth with autism spectrum disorder (ASD). Study sample comprised 6- to 18-year old (N = 213) children and adolescents with ASD. Parents reported regression in 77 (36%) youth. A more homogeneous subgroup with regression between 18 and 36 months (n = 48) had higher rates of intellectual disability, epilepsy, and special education, more socially restrictive educational settings, and more severe ASD communication deficits and schizophrenia spectrum symptoms than non-regressed youth (n = 136). Similar results were obtained for a more inclusive definition of regression (n = 77). A brief parent report of developmental regression may be a useful clinical indicator of later general functioning.
authors.affiliation: Department of Psychiatry, Center for Understanding Biology using Imaging Technology (CUBIT), Stony Brook University, Stony Brook, NY, 11794-8101, USA. kenneth.gadow@stonybrook.edu.
authors.forename: Kenneth D
authors.initials: KD
authors.lastname: Gadow
authors.affiliation: Department of Psychiatry, Center for Understanding Biology using Imaging Technology (CUBIT), Stony Brook University, Stony Brook, NY, 11794-8101, USA.
authors.forename: Greg
authors.initials: G
authors.lastname: Perlman
authors.affiliation: Department of Psychiatry, Center for Understanding Biology using Imaging Technology (CUBIT), Stony Brook University, Stony Brook, NY, 11794-8101, USA.
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Weber
mesh_terms: D000293:Adolescent; D000067877:Autism Spectrum Disorder / Q000523:psychology*; D002648:Child; D004519:Education, Special / Q000379:methods; D004827:Epilepsy / Q000523:psychology*; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D010290:Parents / Q000523:psychology; D012043:Regression, Psychology; D012559:Schizophrenia; D012565:Schizophrenic Psychology