title: [Method and significance of specimens standardized pathological treatment in pancreaticoduodenectomy for pancreatic head cancer].
abstract: Pancreatic ductal adenocarcinoma is a highly aggressive disease with a grim prognosis. Surgical resection offers the best chance for long-term survival. Negative-margin resection still remains the goal, the influence of margin status on outcomes in pancreatic head carcinoma remains controversial, as conflicting data have been plagued by a lack of standardization in R0 resection and margin definitions, pathologic analysis, and reporting. In contrast to common belief, a high rate of R1 resections in pancreatic cancer is not a marker of low-quality surgery but rather of high-quality pathology. The international pathological consensus of pancreatic head carcinoma is still needed to fully understand the prognostic value of margin status in order to optimize treatment strategy for this disease.
authors.affiliation: Department of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai 200092, China.
authors.forename: W G
authors.initials: WG
authors.lastname: Wu
authors.forename: X S
authors.initials: XS
authors.lastname: Wu
authors.forename: M L
authors.initials: ML
authors.lastname: Li
authors.forename: X A
authors.initials: XA
authors.lastname: Wang
authors.forename: H B
authors.initials: HB
authors.lastname: Liang
authors.forename: Y B
authors.initials: YB
authors.lastname: Liu
mesh_terms: D021441:Carcinoma, Pancreatic Ductal / Q000601:surgery*; D006801:Humans; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000601:surgery*; D016577:Pancreaticoduodenectomy; D011379:Prognosis; D015996:Survival Rate