title: Bilateral Hippocampal Restricted Diffusion: Same Picture Many Causes.
abstract: With some regularity, we have encountered the unusual imaging abnormality of bilateral hippocampal restricted diffusion, either in isolation or in combination with other coincident abnormalities. In this retrospective case series, we examine clinical and imaging data to explore potential etiologies and clinical implications of this imaging finding. Sixteen cases with the imaging abnormality are presented, with etiologies including hypoxemia, hypoxemia-ischemia, and seizures.
authors.affiliation: Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
authors.forename: Shamik
authors.initials: S
authors.lastname: Bhattacharyya
authors.affiliation: Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
authors.forename: Taha
authors.initials: T
authors.lastname: Gholipour
authors.affiliation: Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
authors.forename: Rene A
authors.initials: RA
authors.lastname: Colorado
authors.affiliation: Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.|Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
authors.forename: Joshua P
authors.initials: JP
authors.lastname: Klein
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D005260:Female; D006624:Hippocampus / Q000098:blood supply / Q000000981:diagnostic imaging*; D006801:Humans; D000860:Hypoxia / Q000000981:diagnostic imaging*; D007511:Ischemia / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012640:Seizures / Q000000981:diagnostic imaging*; D055815:Young Adult