title: The Effect of Sleep Deprivation on Coronary Heart Disease.
abstract: Sleep deprivation (SD) has been associated with an increased morbidity and mortality of coronary heart disease (CHD). SD could induce autonomic nervous dysfunction, hypertension, arrhythmia, hormonal dysregulation, oxidative stress, endothelial dysfunction, inflammation and metabolic disorder in CHD patients. This paper reviewed the study results of SD in clinical trials and animal experiments and concluded that SD was associated with cardiovascular risk factors, which aggravated CHD in pathogenesis and outcomes.
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053; Beijing University of Chinese Medicine, Beijing 100029.
authors.forename: Rong
authors.initials: R
authors.lastname: Yuan
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053.
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053.
authors.forename: Lili
authors.initials: L
authors.lastname: Guo
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000209:etiology; D003324:Coronary Artery Disease / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D008659:Metabolic Diseases / Q000209:etiology; D018384:Oxidative Stress; D012892:Sleep Deprivation / Q000150:complications*