title: Joint MR-PET Reconstruction Using a Multi-Channel Image Regularizer.
abstract: While current state of the art MR-PET scanners enable simultaneous MR and PET measurements, the acquired data sets are still usually reconstructed separately. We propose a new multi-modality reconstruction framework using second order Total Generalized Variation (TGV) as a dedicated multi-channel regularization functional that jointly reconstructs images from both modalities. In this way, information about the underlying anatomy is shared during the image reconstruction process while unique differences are preserved. Results from numerical simulations and in-vivo experiments using a range of accelerated MR acquisitions and different MR image contrasts demonstrate improved PET image quality, resolution, and quantitative accuracy.
authors.affiliation: Bernard and Irene Schwartz Center for Biomedical Imaging, and the Center for Advanced Imaging Innovation and Research (CAIR), in the Department of Radiology at NYU School of Medicine, New York, NY, United States.
authors.forename: Florian
authors.initials: F
authors.lastname: Knoll
authors.affiliation: Institute of Mathematics and Scientific Computing, University of Graz, Graz, Austria. The Institute of Mathematics and Scientific Computing is a member of NAWI Graz (www.nawigraz.at) and BioTechMed Graz (www.biotechmed.at).
authors.forename: Martin
authors.initials: M
authors.lastname: Holler
authors.affiliation: Bernard and Irene Schwartz Center for Biomedical Imaging, and the Center for Advanced Imaging Innovation and Research (CAIR), in the Department of Radiology at NYU School of Medicine, New York, NY, United States.
authors.forename: Thomas
authors.initials: T
authors.lastname: Koesters
authors.affiliation: Bernard and Irene Schwartz Center for Biomedical Imaging, and the Center for Advanced Imaging Innovation and Research (CAIR), in the Department of Radiology at NYU School of Medicine, New York, NY, United States.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Otazo
authors.affiliation: Institute of Mathematics and Scientific Computing, University of Graz, Graz, Austria. The Institute of Mathematics and Scientific Computing is a member of NAWI Graz (www.nawigraz.at) and BioTechMed Graz (www.biotechmed.at).
authors.forename: Kristian
authors.initials: K
authors.lastname: Bredies
authors.affiliation: Bernard and Irene Schwartz Center for Biomedical Imaging, and the Center for Advanced Imaging Innovation and Research (CAIR), in the Department of Radiology at NYU School of Medicine, New York, NY, United States.
authors.forename: Daniel K
authors.initials: DK
authors.lastname: Sodickson
mesh_terms: D000465:Algorithms; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed