title: Atom-Economic Synthesis of 4-Pyrones from Diynones and Water.
abstract: Transition-metal-free synthesis of 4-pyrones via TfOH-promoted nucleophilic addition/cyclization of diynones and water has been developed. This transformation is simple, atom economical and environmentally benign, providing rapid and efficient access to substituted 4-pyrones.
authors.affiliation: College of Pharmacy, Guilin Medical University, Guilin 541004, China. yanlixu@163.com.
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Xu
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China. qinghuteng@163.com.
authors.forename: Qing-Hu
authors.initials: QH
authors.lastname: Teng
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China. m18778391736@163.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Tong
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China. whengshan@163.com.
authors.forename: Heng-Shan
authors.initials: HS
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China. panym2013@hotmail.com.
authors.forename: Ying-Ming
authors.initials: YM
authors.lastname: Pan
authors.affiliation: College of Pharmacy, Guilin Medical University, Guilin 541004, China. mxl78@glmc.edu.cn.
authors.forename: Xian-Li
authors.initials: XL
authors.lastname: Ma
mesh_terms: D002384:Catalysis; D003500:Cyclization; D053280:Diynes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry
chemical_list: D053280:Diynes; D011753:Pyrones; D014867:Water
keywords: 4-pyrones; diynones; transition-metal-free; water