title: A concise construction of 12H-benzo[4,5]thiazolo[2,3-b]quinazolin-12-ones via an unusual TBHP/Na2CO3promoted cascade oxidative cyclization and interrupted Dimroth rearrangement.
abstract: An efficient transition-metal-free cascade reaction has been developed for the facile synthesis of 12H-benzo[4,5]thiazolo[2,3-b]quinazolin-12-one derivatives from commercially available isatins and 2-haloaryl isothiocyanates. A preliminary mechanistic study suggested an interrupted Dimroth rearrangement was the key step for the successful transformation.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
authors.forename: Zhi-Wen
authors.initials: ZW
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
authors.forename: Feng-Cheng
authors.initials: FC
authors.lastname: Jia
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
authors.forename: Cheng
authors.initials: C
authors.lastname: Xu
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
authors.forename: Shi-Fen
authors.initials: SF
authors.lastname: Jiang
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
authors.forename: Yan-Dong
authors.initials: YD
authors.lastname: Wu
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, P. R. China. chwuyd@mail.ccnu.edu.cn chwuax@mail.ccnu.edu.cn.
authors.forename: An-Xin
authors.identifier: http://orcid.org/0000-0001-7673-210X
authors.initials: AX
authors.lastname: Wu