title: Acute effect of treatment of mitral stenosis on left atrium function.
abstract: OBJECTIVE
  Peak atrial longitudinal strain (PALS) is used to evaluate left atrium (LA) function in patients with mitral stenosis (MS), before and after percutaneous transmitral commissurotomy (PTMC) and mitral valve replacement (MVR).
  
  
  METHODS
  Patients with severe symptomatic MS, who were referred to our echocardiographic laboratory for a diagnostic examination before cardiac surgery or PTMC from October of 2014 to October of 2015, were included in the study.
  
  
  RESULTS
  The peak systolic global LA strain improved post-PTMC (P < 0.001) and post-MVR (P = 0.012). This difference was statistically highly significant.
  
  
  CONCLUSIONS
  PALS is impaired in patients with severe symptomatic MS and improved acutely after treatment and may be a good indicator of LA function and may predict the right time for intervention on mitral valve.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Atooshe
authors.initials: A
authors.lastname: Rohani
authors.affiliation: Mashhad Cardiac Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Shahram
authors.initials: S
authors.lastname: Kargar
authors.affiliation: Mashhad Cardiac Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Afsoon
authors.initials: A
authors.lastname: Fazlinejad
authors.affiliation: Atherosclerosis Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Fereshte
authors.initials: F
authors.lastname: Ghaderi
authors.affiliation: Department of Social Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Vida
authors.initials: V
authors.lastname: Vakili
authors.affiliation: Department of Cardiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Homa
authors.initials: H
authors.lastname: Falsoleiman
authors.affiliation: Department of Cardiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Ramin Khamene
authors.initials: RK
authors.lastname: Bagheri
mesh_terms: D016275:Atrial Function / Q000502:physiology*; D004452:Echocardiography; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000503:physiopathology; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome