title: The Utility of Post-Void Residual Volume versus Sphincter Electromyography to Distinguish between Multiple System Atrophy and Parkinson's Disease.
abstract: OBJECTIVE
  To determine the ability of sphincter electromyography (EMG) and post-void residual urine volume (PVR) during a free-flow study and a pressure-flow study (PFS) for distinguishing multiple system atrophy (MSA) from Parkinson's disease (PD).
  
  
  METHODS
  We retrospectively reviewed 241 case records; both urodynamic study and sphincter EMG were performed in patients with MSA (n = 147) and PD (n = 94).
  
  
  RESULTS
  There was a statistically significant difference (p < 0.01) in the mean PVR during the free-flow study (113.1 ± 7.5 mL in MSA and 40.4 ± 3.8 mL in PD), mean PVR during PFS (230.1 ± 12.6 mL in MSA and 71.7 ± 6.6 mL in PD), and mean duration of MUP for sphincter EMG (9.3 ± 0.1 ms in MSA and 7.7 ± 0.1 ms in PD). The area under the curve used for differentiating MSA from PD was 0.79 and 0.73 for PVR during PFS and the free-flow study, respectively. There was a mean duration of 0.69 ms for the sphincter EMG.
  
  
  CONCLUSIONS
  The present results suggested that PVR was more appropriate than sphincter EMG for differentiating MSA from PD.
authors.affiliation: Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yamamoto
authors.affiliation: Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Asahina
authors.affiliation: Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Yamanaka
authors.affiliation: Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.|Department of Neurology, Continence Center, Dokkyo Medical University, Tochigi, Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Uchiyama
authors.affiliation: Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Hirano
authors.affiliation: Department of Urology, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Miki
authors.initials: M
authors.lastname: Fuse
authors.affiliation: Department of Molecular Diagnosis, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Koga
authors.affiliation: Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.|Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Sakakibara
authors.affiliation: Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kuwabara
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D004576:Electromyography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019578:Multiple System Atrophy / Q000175:diagnosis* / Q000503:physiopathology*; D010300:Parkinson Disease / Q000175:diagnosis* / Q000503:physiopathology*; D012372:ROC Curve; D012189:Retrospective Studies; D057566:Self Report; D014521:Urethra / Q000503:physiopathology*; D014563:Urodynamics