title: Noncompaction cardiomyopathy: The role of advanced multimodality imaging techniques in diagnosis and assessment.
abstract: Noncompaction cardiomyopathy (NCCM) is a unique cardiomyopathy with a diverse array of genotypic and phenotypic manifestations. Its hallmark morphology consists of a bilayered myocardium with a compact epicardial layer and prominent trabeculations that comprise the noncompacted endocardial layer. The controversial diagnostic criteria for NCCM have been frequently discussed in the literature. This review touches on those diagnostic criteria, delves further into the evolving use of advanced imaging techniques within the major imaging modalities (echocardiography, computed tomography, and cardiac magnetic resonance imaging), and proposes an alternative algorithm incorporating these techniques for aiding with the diagnosis of NCCM.
authors.affiliation: Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.
authors.forename: Lakshmi H
authors.initials: LH
authors.lastname: Chebrolu
authors.affiliation: Division of Cardiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: Anjlee M
authors.initials: AM
authors.lastname: Mehta
authors.affiliation: Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Navin C
authors.initials: NC
authors.lastname: Nanda
mesh_terms: D004452:Echocardiography / Q000379:methods*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D064847:Multimodal Imaging / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: cardiac magnetic resonance; computed tomography; echocardiography; left ventricular noncompaction; noncompaction; three-dimensional echocardiography; two-dimensional echocardiography