title: Geographical and epidemiological analysis of oncological incidence in paediatric and adolescent ages in a municipality of North-Western Italy: Vercelli, years 2002-2009.
abstract: This study of the geographical incidence on the oncological mortality in young age (0-44 years) in the City of Vercelli, was aimed to address the concerns of the population and the request of municipal administrators. A detailed and sophisticated study for a City of medium-small size is due for the presence of various sources of pressure, such as a MSW incinerator just a few kilometres from the city and an intensive agricultural activity that characterizes the entire area.
  
  
  
  The study is based on the census analysis of the population, and of the hospital admission cards, and it considers epidemiological standardized estimators and spatial analysis through Bayesian models, as well.
  
  
  
  Both approaches highlight Major risks for the area south of the city for major tumours such as total cancer in women (SIR / SMR significant excess of about 50%), colorectal (mean increments SMR / SIR between 3 and 4 times), ovary (mean increments SMR / SIR between 3:04 and times), and nervous system (increases 3 times for both indicators).
  
  
  
  These results deserve further studies through inferential case-control and cohort analysis, given the marginal role of the possible occupational hazards in the aetiology of juvenile cancer disorders.
authors.affiliation: Department of Translational Medicine. University of Eastern Piedmont "Amedeo Avogadro", Novara, Ital.
authors.forename: C
authors.initials: C
authors.lastname: Salerno
authors.affiliation: Department of Clinical and Biological Sciences. University of Turin, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Berchialla
authors.affiliation: Department of Translational Medicine. University of Eastern Piedmont "Amedeo Avogadro", Novara, Ital.
authors.forename: L A
authors.initials: LA
authors.lastname: Palin
authors.affiliation: Department of Urology, Clinic Santa Rita - Policlinico of Monza, Vercelli, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Barasolo
authors.affiliation: Local Health Agency (ASL) of Vercelli.
authors.forename: P G
authors.initials: PG
authors.lastname: Fossale
authors.affiliation: Department of Pharmacological and Biomolecular Science, University of Milan, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Marciani
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D017745:Incineration; D007223:Infant; D007231:Infant, Newborn; D007558:Italy / Q000453:epidemiology; D008297:Male; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology* / Q000401:mortality; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D015996:Survival Rate; D013997:Time Factors; D014505:Urban Population / Q000706:statistics & numerical data*
keywords: Bayesian model; Juvenile cancer mortality; Province of Vercelli; Spatial analysis