title: Convenient access to 5-arylisoindolo[2,1- α]quinolin-11(6aH)-ones.
abstract: Substituted isoindoloquinolinones were obtained from N-aryl-3-hydroxyisoindolinones and aryl alkynes under Lewis acid-catalyzed conditions in 30-99% yields.
authors.affiliation: Department of Chemistry, Acadia University, Wolfville, NS, Canada.
authors.forename: Melissa
authors.initials: M
authors.lastname: O'Brien
authors.affiliation: Department of Chemistry, Acadia University, Wolfville, NS, Canada.
authors.forename: Rachael
authors.initials: R
authors.lastname: Weagle
authors.affiliation: Department of Chemistry, Acadia University, Wolfville, NS, Canada.
authors.forename: Donald
authors.initials: D
authors.lastname: Corkum
authors.affiliation: Department of Chemistry, Acadia University, Wolfville, NS, Canada.
authors.forename: Minati
authors.initials: M
authors.lastname: Kuanar
authors.affiliation: Department of Chemistry, Acadia University, Wolfville, NS, Canada.
authors.forename: Prabhu P
authors.initials: PP
authors.lastname: Mohapatra
authors.affiliation: Department of Chemistry, Acadia University, Wolfville, NS, Canada. amitabh.jha@acadiau.ca.
authors.forename: Amitabh
authors.initials: A
authors.lastname: Jha
mesh_terms: D015195:Drug Design; D054833:Isoindoles / Q000737:chemistry*; D015363:Quinolones / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D054833:Isoindoles; D015363:Quinolones
keywords: Aryl alkynes; Inverse electron demand cycloaddition; Lewis acid; N-Acyliminium ion; N-Aryl-3-hydroxyisoindolinones