title: An extended retinotopic map of mouse cortex.
abstract: Visual perception and behavior are mediated by cortical areas that have been distinguished using architectonic and retinotopic criteria. We employed fluorescence imaging and GCaMP6 reporter mice to generate retinotopic maps, revealing additional regions of retinotopic organization that extend into barrel and retrosplenial cortices. Aligning retinotopic maps to architectonic borders, we found a mismatch in border location, indicating that architectonic borders are not aligned with the retinotopic transition at the vertical meridian. We also assessed the representation of visual space within each region, finding that four visual areas bordering V1 (LM, P, PM and RL) display complementary representations, with overlap primarily at the central hemifield. Our results extend our understanding of the organization of mouse cortex to include up to 16 distinct retinotopically organized regions.
authors.affiliation: Allen Institute for Brain Science, Seattle, United States.
authors.forename: Jun
authors.identifier: http://orcid.org/0000-0002-6237-3270
authors.initials: J
authors.lastname: Zhuang
authors.affiliation: Allen Institute for Brain Science, Seattle, United States.
authors.forename: Lydia
authors.initials: L
authors.lastname: Ng
authors.affiliation: Allen Institute for Brain Science, Seattle, United States.
authors.forename: Derric
authors.initials: D
authors.lastname: Williams
authors.affiliation: Allen Institute for Brain Science, Seattle, United States.
authors.forename: Matthew
authors.initials: M
authors.lastname: Valley
authors.affiliation: Allen Institute for Brain Science, Seattle, United States.
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.affiliation: Allen Institute for Brain Science, Seattle, United States.
authors.forename: Marina
authors.initials: M
authors.lastname: Garrett
authors.affiliation: Allen Institute for Brain Science, Seattle, United States.
authors.forename: Jack
authors.identifier: http://orcid.org/0000-0002-2312-4183
authors.initials: J
authors.lastname: Waters
mesh_terms: D000818:Animals; D001931:Brain Mapping; D017930:Genes, Reporter; D051379:Mice; D061848:Optical Imaging; D014793:Visual Cortex / Q000033:anatomy & histology* / Q000502:physiology*
keywords: cortex; mouse; neuroscience; topographic map; visual map