title: Pump Thrombosis following HeartMate II Left Ventricular Assist Device Implantation in a Patient with Aspirin and Plavix Resistance.
abstract: Despite advances in pump technology, thromboembolic events and pump thrombosis are potentially life-threatening complications in patients with continuous flow ventricular assist devices. Here we describe a patient with pump thrombosis following LVAD HeartMate II implantation presenting with Aspirin and Plavix resistance and signs of acute hemolysis as manifested by high LDH, changing pump power, pulse index and reduced pump flows.
authors.affiliation: Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, Pennsylvania, USA.|Miami Transplant Institute, University of Miami, Jackson Memorial Hospital, Miami, Florida, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Ghodsizad
authors.affiliation: Miami Transplant Institute, University of Miami, Jackson Memorial Hospital, Miami, Florida, USA.
authors.forename: A
authors.initials: A
authors.lastname: Badiye
authors.affiliation: Nazih Zuhdi Transplant and Advanced Cardiac Care Institute, INTEGRIS Baptist Medical Center, Oklahoma City, Oklahoma, USA.
authors.forename: M
authors.initials: M
authors.lastname: Zeriouh
authors.affiliation: Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, Pennsylvania, USA.
authors.forename: W
authors.initials: W
authors.lastname: Pae
authors.affiliation: Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, Pennsylvania, USA.|Nazih Zuhdi Transplant and Advanced Cardiac Care Institute, INTEGRIS Baptist Medical Center, Oklahoma City, Oklahoma, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Koerner
authors.affiliation: Miami Transplant Institute, University of Miami, Jackson Memorial Hospital, Miami, Florida, USA.
authors.forename: M
authors.initials: M
authors.lastname: Loebe
mesh_terms: D000368:Aged; D001241:Aspirin / Q000627:therapeutic use*; D000077144:Clopidogrel; D004351:Drug Resistance; D006333:Heart Failure / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011475:Prosthesis Failure; D012189:Retrospective Studies; D013927:Thrombosis; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin