title: Outcome of stent grafting for esophageal perforations: single-center experience.
abstract: Recent studies showed that stent grafting is a promising technique for treatment of esophageal perforation. However, the evidence of its benefits is still scarce.
  
  
  
  Forty-three consecutive patients underwent stent grafting for esophageal perforation at the Oulu University Hospital, Finland. The main endpoints of this study were early and mid-term mortality. Secondary outcome endpoints were the need of esophagectomy and additional surgical procedures on the esophagus and extraesophageal structures.
  
  
  
  Patients' mean age was 64.6 ± 13.4 years. The mean delay to primary treatment was 23 ± 27 h. The most frequent cause of perforation was Boerhaave's syndrome (46.5%). The thoraco-abdominal segment of the esophagus was affected in 58.1% of cases. Minor primary procedures were performed in 25 patients (58.1%) and repeat surgical procedures in 23 patients (53.5%). Forty-nine repeat stent graftings were performed in 22 patients (50%). Two patients (4.7%) underwent esophagectomy, one for unrelenting preprocedural stricture of the esophagus and another for persistent leakage of a perforated esophageal carcinoma. The mean length of stay in the intensive care unit was 6.0 ± 7.5 days and the in-hospital stay was 24.3 ± 19.6 days. In-hospital mortality was 4.6%. Three-year survival was 67.2%.
  
  
  
  Stent grafting seems to be an effective less invasive technique for the treatment of esophageal perforation. Repeat stent grafting and procedures on the pleural spaces are often needed to control the site of perforation and for debridement of surrounding infected structures. Stent grafting allows the preservation of the esophagus in most of patients. The mid-term survival of these patients is suboptimal and requires further investigation.
authors.affiliation: Department of Surgery, Oulu University Hospital, PL 21, 90029, Oulu, Finland. faustobiancari@yahoo.it.
authors.forename: Fausto
authors.initials: F
authors.lastname: Biancari
authors.affiliation: Department of Surgery, Oulu University Hospital, PL 21, 90029, Oulu, Finland.
authors.forename: Tuomas
authors.initials: T
authors.lastname: Tauriainen
authors.affiliation: Department of Surgery, Oulu University Hospital, PL 21, 90029, Oulu, Finland.
authors.forename: Tatu
authors.initials: T
authors.lastname: Ylikotila
authors.affiliation: Department of Surgery, Central Ostrobothnia Central Hospital, Kokkola, Finland.
authors.forename: Misa
authors.initials: M
authors.lastname: Kokkonen
authors.affiliation: Department of Surgery, Lapland Central Hospital, Rovaniemi, Finland.
authors.forename: Jukka
authors.initials: J
authors.lastname: Rintala
authors.affiliation: Department of Surgery, Kainuu Central Hospital, Kajaani, Finland.
authors.forename: Elisa
authors.initials: E
authors.lastname: Mäkäräinen-Uhlbäck
authors.affiliation: Department of Surgery, Oulu University Hospital, PL 21, 90029, Oulu, Finland.
authors.forename: Vesa
authors.initials: V
authors.lastname: Koivukangas
authors.affiliation: Department of Surgery, Oulu University Hospital, PL 21, 90029, Oulu, Finland.
authors.forename: Juha
authors.initials: J
authors.lastname: Saarnio
mesh_terms: D000328:Adult; D000368:Aged; D004939:Esophageal Perforation / Q000150:complications / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D005260:Female; D005387:Finland; D017052:Hospital Mortality; D006785:Hospitals, University; D006801:Humans; D007049:Iatrogenic Disease; D007902:Length of Stay / Q000706:statistics & numerical data*; D008297:Male; D008477:Mediastinal Diseases / Q000150:complications* / Q000401:mortality; D008875:Middle Aged; D015607:Stents; D016896:Treatment Outcome; D004935:Esophageal Diseases; D012422:Rupture, Spontaneous; D000072663:Spontaneous Perforation
keywords: Esophagectomy; Esophagus; Oesophagus; Perforation; Stent graft; Stent grafting