title: Independent psychometric validation of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24).
abstract: The endometrial cancer (EC)-specific Quality of Life module of the European Organization for Research and Treatment of Cancer (EORTC QLQ-EN24), was developed and validated in one study. We independently validated and assessed the psychometric properties of the instrument. Two hundred and eight women with EC before surgery, during adjuvant treatment and follow-up; in three different cancer centres completed the EORTC QLQ-C30 and the EN24. The questionnaire's completion rate was 100%, except sexuality items, that were answered by 35% of patients. All item-scale correlations for the multi-item scales exceeded the .4 criterion and correlated well with their own scale, while correlations with the other scales were low. The internal consistency of all multi-item scales were satisfactory (Cronbach's alpha coefficients ranging from .77 to .97). Discriminance for single-item scales was low. The QLQ-EN24 module discriminated well between clinically different patients, and there were no differences in quality of life questionnaire scales between patients with body mass index ≤30 when compared to those with >30. This validation study supports the reliability, as well as convergent and divergent validity of the EORTC QLQ-EN24. The module is a useful instrument for the assessment of QOL in patients with EC. However, data concerning sexuality should be interpreted with caution.
authors.affiliation: Department of Gynaecologic Oncology, Gdynia Oncology Centre, Gdynia, Poland.|Medicover Outpatient Clinic, Gdańsk, Poland.
authors.forename: M
authors.identifier: http://orcid.org/0000-0003-2376-4663
authors.initials: M
authors.lastname: Stukan
authors.affiliation: Department of Clinical Oncology, Holycross Cancer Centre, Kielce, Poland.|Clinical Department of Obstetrics, Female Diseases and Gynaecological Oncology, II Medical Faculty, Medical University of Warsaw, Warsaw, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Zalewski
authors.affiliation: Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Poznan, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Mardas
authors.affiliation: Department of Radiotherapy, Gdynia Oncology Centre, Gdynia, Poland.
authors.forename: D
authors.initials: D
authors.lastname: Filarska
authors.affiliation: Department of Propaedeutics of Oncology, Faculty of Health Sciences, Medical University of Gdańsk, Gdańsk, Poland.|Department of Surgical Oncology, Gdynia Oncology Centre, Gdynia, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Szajewski
authors.affiliation: Department of Gynaecologic Oncology, Gdynia Oncology Centre, Gdynia, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Kmieć
authors.affiliation: Department of Medical Oncology, Gdynia Oncology Centre, Gdynia, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Bińkowska
authors.affiliation: Medicover Outpatient Clinic, Gdańsk, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Pietrzak-Stukan
authors.affiliation: Department of Gynaecologic Oncology, Gdynia Oncology Centre, Gdynia, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Dudziak
authors.affiliation: Department of Gynaecology, Charite-University of Medicine, Berlin, Germany.
authors.forename: J P
authors.initials: JP
authors.lastname: Grabowski
authors.affiliation: Department of Obstetrics & Gynaecology, University of California Irvine Medical Centre, Orange, CA, USA.
authors.forename: R N
authors.initials: RN
authors.lastname: Eskander
authors.affiliation: Department of Obstetrics and Gynaecology, Medical University of Graz, Graz, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Greimel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales / Q000592:standards; D011594:Psychometrics; D011788:Quality of Life; D011795:Surveys and Questionnaires / Q000592:standards*
keywords: endometrial cancer; quality of life; questionnaire; validation