title: Biotechnological Patents Applications of the Deuterium Oxide in Human Health.
abstract: BACKGROUND
  Deuterium oxide is a molecule that has been used for decades in several studies related to human health. Currently, studies on D2O have mobilized a "Race for Patenting" worldwide. Several patents have been registered from biomedical and technological studies of D2O showing the potential of this stable isotope in industry and health care ecosystems.
  
  
  METHODS
  Most of the patents related to the applications of the deuterium oxide in human health have been summarized in this review. The following patents databases were consulted: European Patent Office (Espacenet), the United States Patent and Trademark Office (USPTO), the United States Latin America Patents (LATIPAT), Patent scope -Search International and National Patent Collections (WIPO), Google Patents and Free Patents Online.
  
  
  RESULTS
  With this review, the information was collected on recent publications including 22 patents related to deuterium oxide and its applications in different areas.
  
  
  CONCLUSIONS
  This review showed that deuterium oxide is a promising component in different areas, including biotechnology, chemistry and medicine. In addition, the knowledge of this compound was covered, reinforcing its importance in the field of biotechnology and human health.
authors.affiliation: Universidade Federal de São João Del-Rei (UFSJ/CCO), Laboratório de Biotecnologia de Microrganismos, Divinópolis, MG, 35501-296. Brazil.
authors.forename: Reysla M
authors.initials: RM
authors.lastname: da S Mariano
authors.affiliation: Universidade Federal de São João Del-Rei (UFSJ/CCO), Laboratório de Biotecnologia de Microrganismos, Divinópolis, MG, 35501-296. Brazil.
authors.forename: Wendell C
authors.initials: WC
authors.lastname: Bila
authors.affiliation: Universidade Federal de São João Del-Rei (UFSJ/CCO), Laboratório de Biotecnologia de Microrganismos, Divinópolis, MG, 35501-296. Brazil.
authors.forename: Maria Jaciara F
authors.initials: MJF
authors.lastname: Trindade
authors.affiliation: Universidade Federal de São João Del-Rei (UFSJ/CCO), Laboratório de Biotecnologia de Microrganismos, Divinópolis, MG, 35501-296. Brazil.
authors.forename: Joel A
authors.initials: JA
authors.lastname: Lamounier
authors.affiliation: Laboratório de Biotecnologia de Microrganismos, Universidade Federal de São João Del-Rei, Divinópolis, MG, 355901-296. Brazil.
authors.forename: Alexsandro S
authors.initials: AS
authors.lastname: Galdino
mesh_terms: D001709:Biotechnology / Q000331:legislation & jurisprudence* / Q000379:methods; D016208:Databases, Factual; D017666:Deuterium Oxide / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010330:Patents as Topic
chemical_list: D017666:Deuterium Oxide
keywords: Biotechnology; chemicals; deuterium oxide; diseases; human health; imaging exams.; patents