title: The Missing Link in the Diagnostic Pathway of Prostate Cancer.
abstract: Prostate cancer is one of the most common cancers in the Western world. It is among the leading causes of cancer related death. While its incidence and survival increased significantly during the last few decades in Denmark, the mortality rate did not change for patients younger than 80 year old. Development of new techniques, such as multiparametric MRI, helps to increase the accuracy of diagnosis. However, a missing link in the diagnostic pathway may result in mistreatment if an acinar adenocarcinoma of prostate is transformed into a neuroendocrine phenotype such as small cell carcinoma.
authors.affiliation: Patologisk Institut, Regionshospitalet Viborg, Pakhusvej 1, 8800, Viborg, Denmark.
authors.forename: Arne Vidar Tind
authors.initials: AV
authors.lastname: Wøyen
authors.affiliation: Urologisk Afdeling, Regionshospitalet Viborg, Viborg, Denmark.
authors.forename: Gergely
authors.initials: G
authors.lastname: Laczkó
authors.affiliation: Patologisk Institut, Aarhus Universitetshospital, Aarhus, Denmark.
authors.forename: Søren
authors.initials: S
authors.lastname: Høyer
authors.affiliation: Patologisk Institut, Regionshospitalet Viborg, Pakhusvej 1, 8800, Viborg, Denmark. lhegyi@doctors.org.uk.
authors.forename: Laszlo
authors.identifier: http://orcid.org/0000-0003-0296-1836
authors.initials: L
authors.lastname: Hegyi
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology*
keywords: Adenocarcinoma; Immunohistochemistry; Prostatic carcinoma; Small cell carcinoma