title: Functionalization of C-H Bonds by Photoredox Catalysis.
abstract: Visible-light photoredox catalysis has been successfully used in the functionalization of inert C-H bonds including C(sp2)-H bonds of arenes and C(sp3)-H bonds of aliphatic compounds over the past decade. These transformations are typically promoted by the process of single-electron-transfer (SET) between substrates and photo-excited photocatalyst upon visible light irradiation (household bulbs or LEDs). Compared with other synthetic strategies, such as the transition-metal catalysis and traditional radical reactions, visible-light photoredox approach has distinct advantages in terms of operational simplicity and practicability. Versatile direct functionalization of inert C(sp2)-H and C(sp3)-H bonds including alkylation, trifluoromethylation, arylation and amidation, has been achieved using this practical strategy.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
authors.forename: Qixue
authors.initials: Q
authors.lastname: Qin
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
authors.forename: Heng
authors.initials: H
authors.lastname: Jiang
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
authors.forename: Zhentao
authors.initials: Z
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
authors.forename: Daan
authors.initials: D
authors.lastname: Ren
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
authors.forename: Shouyun
authors.initials: S
authors.lastname: Yu
keywords: C−H functionalization; photochemistry; photoredox; radical; visible light