title: Successfully treated congenital cystic adenomatoid malformation by open fetal surgery: A care-compliant case report of a 5-year follow-up and review of the literature.
abstract: BACKGROUND
  Congenital cystic adenomatoid malformation (CCAM) is a rare hamartomatous cystic lesion. Open fetal surgery currently provides a potential therapeutic option for management of a fetus with CCAM diagnosis.
  
  
  METHODS
  A 22-year-old G2P0 woman presented at (Equation is included in full-text article.)weeks' gestation for evaluation of a fetus with a left lung lesion and diagnosed as CCAM at (Equation is included in full-text article.)weeks' gestation. Open fetal surgery was performed to resection the lesion at (Equation is included in full-text article.)weeks' gestation under deep maternal general anesthesia. The mother presented at (Equation is included in full-text article.)weeks after open fetal surgery with preterm premature rupture of membranes (PPROM) and underwent cesarean delivery at (Equation is included in full-text article.)weeks' gestation. A vigorous woman infant of 1955 g, with good Apgar score, was delivered. At 1 month, 4 years, and present, 5 years after birth, she has continued to do well without any obvious deficit and both respiration and circulation were well maintained.
  
  
  CONCLUSIONS
  We present one case of CCAM which was cured by open fetal surgery and continued to do well at follow-up of 5 years. The success of treatment provided preliminary experience for further carrying out such interventions in China.
authors.affiliation: aFoshan Fetal Treatment Center bDepartment of Obstetrics, Southern Medical University Affiliated Maternal & Child Health Hospital of Foshan, Foshan, Guangdong cDepartment of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
authors.forename: Dazhi
authors.initials: D
authors.lastname: Fan
authors.forename: Shuzhen
authors.initials: S
authors.lastname: Wu
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Huang
authors.forename: Yao
authors.initials: Y
authors.lastname: Fu
authors.forename: Wen
authors.initials: W
authors.lastname: Ai
authors.forename: Meng
authors.initials: M
authors.lastname: Zeng
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Guo
authors.forename: Zhengping
authors.initials: Z
authors.lastname: Liu
mesh_terms: D002681:China; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D046128:Fetal Therapies / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal; D055815:Young Adult