title: Factors Contributing to Depression and Chronic Pain in Patients with Hidradenitis Suppurativa: Results from a Single-Center Retrospective Review.
abstract: BACKGROUND
  Hidradenitis suppurativa (HS) is a debilitating chronic disease that leads to inflammation and abscess formation in the involved skin, along with a malodorous discharge. Pain is a considerable aspect of HS and significantly impacts quality of life. In addition, HS is significantly associated with depression. A better understanding of contributing factors to depression and pain in patients with HS can identify opportunities to improve care for patients.
  
  
  OBJECTIVE
  To identify factors that contribute to depression and chronic pain in patients with HS.
  
  
  METHODS
  This is a retrospective chart review of 283 patients seen at dermatology clinics of an academic health center for HS from July 2012 to December 2015. The association between HS and depression and chronic pain was assessed in multivariate models using logistic regression analyses.
  
  
  RESULTS
  Patients with a greater number of areas of involvement were more likely to have both chronic pain and depression.
  
  
  CONCLUSIONS
  This is a single-center retrospective chart review with a limited sample size.
  
  
  CONCLUSIONS
  This study suggests that the extent of disease rather than severity plays a role in reducing the quality of life in HS patients.
authors.affiliation: Center for Clinical Studies, Webster, TX, USA.
authors.forename: Ramya
authors.initials: R
authors.lastname: Vangipuram
authors.forename: Toral
authors.initials: T
authors.lastname: Vaidya
authors.forename: Roman
authors.initials: R
authors.lastname: Jandarov
authors.forename: Ali
authors.initials: A
authors.lastname: Alikhan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D059350:Chronic Pain / Q000209:etiology; D003863:Depression / Q000209:etiology; D005260:Female; D017497:Hidradenitis Suppurativa / Q000150:complications / Q000523:psychology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
keywords: Chronic pain; Depression; Hidradenitis suppurativa