title: Spontaneously developed paraplegia in a patient with Factor V Leiden mutation.
abstract: Factor V Leiden (FVL) mutation is the one-point mutation in G1691A in the tenth exon of the gene for Factor V, caused by the substitution of glutamine for arginine at codon 506. We present here a patient with a mutation of the Factor V gene and taking anticoagulant therapy, who became paraplegic following surgery for dural hematoma and spontaneous spinal intramedullary hematoma. His physical examination revealed T5 ASIA A, complete paraplegia. Our case is important in the literature, as being the first case with spinal intramedullary hematoma that developed due to anticoagulant use.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Abant Izzet Baysal University Medical Faculty , Bolu, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Boyraz
authors.affiliation: Department of Physical Medicine and Rehabilitation, Abant Izzet Baysal University Medical Faculty , Bolu, Turkey.
authors.forename: Bunyamin
authors.initials: B
authors.lastname: Koc
authors.affiliation: Department of Physical Medicine and Rehabilitation, Abant Izzet Baysal University Medical Faculty , Bolu, Turkey.
authors.forename: Sirzat
authors.initials: S
authors.lastname: Cogalgil
keywords: Outcomes research; Spinal cord diseases