title: Zinc sulfide nanosheets as a novel solid-phase extraction material for flavonoids.
abstract: As a novel solid-phase extraction material, zinc sulfide nanosheets were prepared by a simple method and were used to extract flavonoids. We used scanning electron microscopy to show its nanosheet morphology and energy dispersive X-ray spectroscopy and powder X-ray diffraction to confirm its chemical and phase compositions. Coupled to a high-performance liquid chromatography, the zinc sulfide nanosheets were packed into a microcolumn and were used to extract four model flavonoids to examine their extraction ability. The parameters of sample loading and elution were investigated. Under optimized conditions, the analytical method for flavonoids was established. For the method, wide linearities from 1 to 250 μg/L and low limits of detection from 0.25 to 0.5 μg/L were obtained. The relative standard deviations for single column repeatability and column to column reproducibility were less than 7.7 and 10.4%, respectively. The established method was also used to analyze two real samples and the recoveries from 88.7 to 98.2% further proved the reliability of the method. Moreover, the zinc sulfide nanosheets have good stability and that in one column can be reused for more than 50 times. This work proves that the prepared zinc sulfide nanosheets are a good candidate as the flavonoids sorbent.
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources, Chinese Academy of Sciences, Lanzhou, P.R. China.|Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P.R. China.
authors.forename: Licheng
authors.initials: L
authors.lastname: Wang
authors.affiliation: Exploration and Development Research Institute, Changqing Oilfield, Xi'an, P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Fan
authors.affiliation: Exploration and Development Research Institute, Changqing Oilfield, Xi'an, P.R. China.
authors.forename: Shuman
authors.initials: S
authors.lastname: Li
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources, Chinese Academy of Sciences, Lanzhou, P.R. China.|Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P.R. China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Jia
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources, Chinese Academy of Sciences, Lanzhou, P.R. China.|Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P.R. China.
authors.forename: Xiudan
authors.initials: X
authors.lastname: Hou
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources, Chinese Academy of Sciences, Lanzhou, P.R. China.|Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P.R. China.
authors.forename: Xusheng
authors.initials: X
authors.lastname: Wang
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources, Chinese Academy of Sciences, Lanzhou, P.R. China.|Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P.R. China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Wang
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources, Chinese Academy of Sciences, Lanzhou, P.R. China.|Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P.R. China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Guo
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000302:isolation & purification*; D049329:Nanostructures; D015203:Reproducibility of Results; D052616:Solid Phase Extraction; D013440:Sulfides; D017967:Zinc Compounds
chemical_list: D005419:Flavonoids; D013440:Sulfides; D017967:Zinc Compounds; C031238:zinc sulfide
keywords: flavonoids; high-performance liquid chromatography; sample pretreatment; solid-phase extraction; zinc sulfide