title: Palladium-Catalyzed Decarboxylative Allylation/Wittig Reaction: Substrate-Controlled Synthesis of C-Vinyl Glycosides.
abstract: A palladium-catalyzed one-pot Tsuji-Trost type decarboxylative allylation/Wittig reaction has been developed to synthesize C-vinyl glycosides. Screening of various aldehydes led to formation of β,(E)-selective C-vinyl glycosides with pyridyl group containing aldehydes and β,(Z)-selective C-vinyl glycosides with nonpyridyl aldehydes. A plausible mechanism is proposed based on the coordination effect of the aldehydes.
authors.affiliation: Division of Chemistry and Biological Chemistry Nanyang Technological University , School of Physical & Mathematical Sciences, 21 Nanyang Link, Singapore 637371, Singapore.
authors.forename: Wei-Lin
authors.initials: WL
authors.lastname: Leng
authors.affiliation: Division of Chemistry and Biological Chemistry Nanyang Technological University , School of Physical & Mathematical Sciences, 21 Nanyang Link, Singapore 637371, Singapore.
authors.forename: Hongze
authors.initials: H
authors.lastname: Liao
authors.affiliation: Division of Chemistry and Biological Chemistry Nanyang Technological University , School of Physical & Mathematical Sciences, 21 Nanyang Link, Singapore 637371, Singapore.
authors.forename: Hui
authors.initials: H
authors.lastname: Yao
authors.affiliation: Division of Chemistry and Biological Chemistry Nanyang Technological University , School of Physical & Mathematical Sciences, 21 Nanyang Link, Singapore 637371, Singapore.
authors.forename: Zi-En
authors.initials: ZE
authors.lastname: Ang
authors.affiliation: Division of Chemistry and Biological Chemistry Nanyang Technological University , School of Physical & Mathematical Sciences, 21 Nanyang Link, Singapore 637371, Singapore.
authors.forename: Shaohua
authors.initials: S
authors.lastname: Xiang
authors.affiliation: Division of Chemistry and Biological Chemistry Nanyang Technological University , School of Physical & Mathematical Sciences, 21 Nanyang Link, Singapore 637371, Singapore.
authors.forename: Xue-Wei
authors.identifier: 0000-0002-8327-6664
authors.initials: XW
authors.lastname: Liu