title: Concentrations of organophosphorus, polybromobenzene, and polybrominated diphenyl ether flame retardants in human serum, and relationships between concentrations and donor ages.
abstract: Organophosphorus flame retardants, polybromobenzenes, and polybrominated diphenyl ethers (PBDEs) were determined in pooled human serum samples collected in an area in which these chemicals are produced in North China. Tri (2-chloroethyl) phosphate (TCEP) was found at a higher concentration than the other chemicals, and the mean TCEP concentration was 480.4 ng/g lipid. This is the first time TCEP has been detected in human serum from China. The PBDE concentration in serum was found to have decreased between 2007 and 2013. BDE-209 remained the dominant PBDE congener, and its mean concentration was 91.3 ng/g lipid in this study. The polybromobenzene concentrations were relatively low, but pentabromobenzene and pentabromotoluene were found in very many of the samples. The highest TCEP, tris(2-butoxyethyl)phosphate, pentabromobenzene, and pentabromotoluene concentrations were found in samples from young people (<30 y old). This suggests that the risks posed by these alternative flame retardants also need more concerns.
authors.affiliation: College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.affiliation: College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China; Engineering Research Center of Food Environment and Public Health, Beijing 100081, China. Electronic address: junjin3799@126.com.
authors.forename: Jun
authors.initials: J
authors.lastname: Jin
authors.affiliation: College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.affiliation: College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China.
authors.forename: Jicheng
authors.initials: J
authors.lastname: Hu
authors.affiliation: College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Xu
authors.affiliation: College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China.
authors.forename: Yiming
authors.initials: Y
authors.lastname: Sun
authors.affiliation: College of Life and Environment Sciences, Minzu University of China, Beijing 100081, China.
authors.forename: Yulong
authors.initials: Y
authors.lastname: Ma
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001555:Benzene Derivatives / Q000097:blood*; D002681:China; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D005411:Flame Retardants / Q000032:analysis*; D055768:Halogenated Diphenyl Ethers / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D009943:Organophosphorus Compounds / Q000097:blood*; D055815:Young Adult
chemical_list: D001555:Benzene Derivatives; D004785:Environmental Pollutants; D005411:Flame Retardants; D055768:Halogenated Diphenyl Ethers; D009943:Organophosphorus Compounds
keywords: Organophosphorus; Polybrominated diphenyl ethers; Polybromobenzenes; Pooled human serum; Trends