title: Evaluation of Dose Homogeneity in Cone-Beam Breast Computed Tomography.
abstract: The aim of this study is to determine, via measurements on phantoms and Monte Carlo (MC) simulations, the dose distribution of absorbed dose in a cone-beam breast computed tomography scan. The absorbed dose volume distribution was measured inside a polyethylene cylindrical phantom, simulating adipose breast tissue, using LiF:Mg,Ti thermoluminescence dosimeters. A reasonable agreement (between 2 and 8%) between the simulated and measured data was observed. The 3D distribution of absorbed dose was evaluated at 40, 60 and 80 kV in a phantom simulating a pendant breast. MC simulations indicate a significantly lower spread of volume dose than in mammography. The dose variation along the radial distance in the simulated phantoms was in the range of 4‒14%. These findings might be useful when devising models for breast imaging dose assessment that take into account the uneven distribution of the glandular mass in the breast volume.
authors.affiliation: Dipartimento di Fisica 'Ettore Pancini', Università di Napoli Federico II, Napoli, Italy.|Istituto Nazionale di Fisica Nucleare, Sezione di Napoli, Napoli, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Mettivier
authors.affiliation: Dipartimento di Fisica, Università di Trieste, Trieste, Italy.|Alma Mater Studiorum, Dipartimento di Fisica e Astronomia, Università di Bologna, Bologna, Italy.
authors.forename: Matilde
authors.initials: M
authors.lastname: Costa
authors.affiliation: Alma Mater Studiorum, Dipartimento di Fisica e Astronomia, Università di Bologna, Bologna, Italy.|Istituto Nazionale di Fisica Nucleare, Sezione di Bologna, Bologna, Italy.
authors.forename: Nico
authors.initials: N
authors.lastname: Lanconelli
authors.affiliation: Dipartimento di Fisica 'Ettore Pancini', Università di Napoli Federico II, Napoli, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Ianiro
authors.affiliation: Dipartimento di Fisica 'Ettore Pancini', Università di Napoli Federico II, Napoli, Italy.|Istituto Nazionale di Fisica Nucleare, Sezione di Napoli, Napoli, Italy.
authors.forename: Mariagabriella
authors.initials: M
authors.lastname: Pugliese
authors.affiliation: Dipartimento di Fisica 'Ettore Pancini', Università di Napoli Federico II, Napoli, Italy.|Istituto Nazionale di Fisica Nucleare, Sezione di Napoli, Napoli, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Quarto
authors.affiliation: Dipartimento di Fisica 'Ettore Pancini', Università di Napoli Federico II, Napoli, Italy.|Istituto Nazionale di Fisica Nucleare, Sezione di Napoli, Napoli, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Russo
mesh_terms: D001940:Breast / Q000000981:diagnostic imaging*; D054893:Cone-Beam Computed Tomography; D005260:Female; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011874:Radiometry