title: Primary sarcomatoid carcinoma of the small intestine: very rare and aggressive tumour.
abstract: Sarcomatoid carcinoma of the small intestine is a very rare and aggressive variant of small intestinal cancers with poor prognosis. The tumour primarily affects middle-aged and older patients with a mean age of 57 years at the time of presentation. We report a woman aged 58 years without any relevant medical history who presented with small intestinal obstruction. She underwent radiologic and endoscopy investigation with persistent features of small bowel obstruction. The patient was found to have a small bowel tumour causing the obstruction and underwent surgical excision of the tumour. Pathology revealed malignant neoplasm with sarcomatoid and epithelioid features involving the terminal ileum. The use of immunohistochemical markers helps in wide range of differential diagnoses. Surgical resection is still considered the best and first-line therapy with poor response to chemotherapy and radiotherapy.
authors.affiliation: Department of Surgery, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine, Staten Island, New York, USA.|Department of Minimally Invasive Surgery, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine, Staten Island, New York, USA.
authors.forename: Peter Abotaga
authors.initials: PA
authors.lastname: Andrawes
authors.affiliation: Department of Surgery, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine, Staten Island, New York, USA.
authors.forename: Masood
authors.initials: M
authors.lastname: Shariff
authors.affiliation: Department of Pathology, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine. Staten Island, New York, USA.
authors.forename: Qing
authors.initials: Q
authors.lastname: Chang
authors.affiliation: Department of Surgery, Staten Island University Hospital, Northwell Health System, Hofstra School of Medicine, Staten Island, New York, USA.
authors.forename: Roman
authors.initials: R
authors.lastname: Grinberg
mesh_terms: D002277:Carcinoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D007415:Intestinal Obstruction / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012509:Sarcoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed