title: INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE VERSUS COMPLETE INTERNAL LIMITING MEMBRANE REMOVAL IN MYOPIC MACULAR HOLE SURGERY: A Comparative Study.
abstract: OBJECTIVE
  To compare the results of vitrectomy with complete internal limiting membrane (ILM) removal and inverted ILM flap in the treatment of myopic macular hole (MMH).
  
  
  METHODS
  Seventy eyes of 68 patients with MMH undergone pars-plana vitrectomy (PPV) with either complete ILM removal (n = 36, Group 1) or inverted ILM flap technique (n = 34, Group 2) were included in the study. Outcomes measured were the rate of MMH closure assessed by optical coherence tomography (OCT) and visual acuity (BCVA) at six months.
  
  
  RESULTS
  Closure of MMH was achieved in 22 cases of Group 1 (61%) and in 32 cases of Group 2 (94%). Surgical failure was reported in 14 cases of Group 1 (39%) and in one case of Group 2 (3%). Average best-corrected visual acuity (BCVA) changed from 0.60 to 0.58 in Group 1 (P = 0.329) and from 0.70 to 0.39 in Group 2 (P < 0.01). Logistic regression analysis showed that inverted ILM flap technique was associated with 22 times higher probability of anatomic success, regardless of the MMH diameter.
  
  
  CONCLUSIONS
  Inverted ILM flap should be preferred to complete ILM removal for the treatment of MMH. The outcomes reported with this technique were better than any other technique described until now.
authors.affiliation: *Department of Ophthalmology, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy; and †Department of Computer Science, University of Verona, Verona, Italy.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Mete
authors.forename: Alessandro
authors.initials: A
authors.lastname: Alfano
authors.forename: Massimo
authors.initials: M
authors.lastname: Guerriero
authors.forename: Guido
authors.initials: G
authors.lastname: Prigione
authors.forename: Mauro
authors.initials: M
authors.lastname: Sartore
authors.forename: Antonio
authors.initials: A
authors.lastname: Polito
authors.forename: Grazia
authors.initials: G
authors.lastname: Pertile
mesh_terms: D001485:Basement Membrane / Q000637:transplantation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications* / Q000503:physiopathology; D012167:Retinal Perforations / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D013524:Surgical Flaps; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods*; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*