title: Demyelinating Peripheral Neuropathy Due to Renal Cell Carcinoma.
abstract: Renal cell carcinoma (RCC) patients who develop a paraneoplastic syndrome may present with neuromuscular disorders. We herein report the case of a 50-year-old man who suffered from progressive gait disturbance and muscle weakness. The results of a nerve conduction study fulfilled the criteria of chronic inflammatory demyelinating polyneuropathy. An abdominal CT scan detected RCC, the pathological diagnosis of which was clear cell type. After tumor resection and a single course of intravenous immunoglobulin therapy, the patient's symptoms drastically improved over the course of one year. The patient's neurological symptoms preceded the detection of cancer. A proper diagnosis and the initiation of suitable therapies resulted in a favorable outcome.
authors.affiliation: Department of Neurology, Juntendo University School of Medicine, Japan.
authors.forename: Kenya
authors.initials: K
authors.lastname: Nishioka
authors.forename: Motoki
authors.initials: M
authors.lastname: Fujimaki
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Kanai
authors.forename: Yuta
authors.initials: Y
authors.lastname: Ishiguro
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nakazato
authors.forename: Ryota
authors.initials: R
authors.lastname: Tanaka
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Yokoyama
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Hattori
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D016756:Immunoglobulins, Intravenous