title: Sulfur dioxide prodrugs: triggered release of SO2via a click reaction.
abstract: Sulfur dioxide (SO2) is being recognized as a possible endogenous gasotransmitter with importance on par with that of NO, CO, and H2S. Herein we describe a series of SO2prodrugs that are activated for SO2release via a bioorthogonal click reaction. The release rate can be tuned by adjusting the substituents on the prodrug.
authors.affiliation: Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, USA. xji@gsu.edu wang@gsu.edu.
authors.forename: Wenyi
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, USA. xji@gsu.edu wang@gsu.edu.
authors.forename: Xingyue
authors.initials: X
authors.lastname: Ji
authors.affiliation: Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, USA. xji@gsu.edu wang@gsu.edu.
authors.forename: Zhenming
authors.initials: Z
authors.lastname: Du
authors.affiliation: Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, USA. xji@gsu.edu wang@gsu.edu.
authors.forename: Binghe
authors.identifier: http://orcid.org/0000-0002-2200-5270
authors.initials: B
authors.lastname: Wang