title: Peach gum polysaccharides improve the spermatogenesis of KKAy mice with impaired reproduction system.
abstract: OBJECTIVE
  Peach gum polysaccharides (PGPs) exhibit antioxidant and antibacterial activities. Nevertheless, the effect of PGPs on the spermatogenesis of KKAy mice with impaired reproduction system remains undetermined.
  
  
  METHODS
  PGPs were extracted with hot water. KKAy mice were randomly divided into two groups, namely, control and PGPs (treated with 100 mg/kg PGPs).
  
  
  RESULTS
  Oral administration of PGPs decreased the levels of serum triglyceride, total cholesterol, low-density lipoprotein cholesterol, fasting blood glucose, plasma insulin, and nitrate nitrogen level in the testes of KKAy mice. Moreover, treatment with PGPs increased the sperm density, sperm movement, rate of normal sperm morphology, protein expression level, and superoxide dismutase activity.
  
  
  CONCLUSIONS
  PGPs can effectively protect the spermatogenesis of KKAy mice with impaired reproduction system.
authors.affiliation: Department of Clinical Laboratory, The Second People's Hospital of Lianyungang, Haizhou, China.
authors.forename: Li
authors.initials: L
authors.lastname: Qian
authors.affiliation: Department of Clinical Laboratory, The Second People's Hospital of Lianyungang, Haizhou, China.
authors.forename: Wenjun
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Oncology, The People's Hospital of Guanyun County, Lianyungang, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Song
authors.affiliation: Department of Respiratory, The People's Hospital of Guanyun County, Lianyungang, China.
authors.forename: Dezhong
authors.initials: D
authors.lastname: Chen
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D052179:Antigens, Plant / Q000378:metabolism*; D000975:Antioxidants / Q000378:metabolism*; D007248:Infertility, Male / Q000235:genetics / Q000276:immunology*; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D011134:Polysaccharides / Q000378:metabolism*; D000068239:Prunus persica / Q000276:immunology; D055101:Semen Analysis; D013091:Spermatogenesis / Q000235:genetics; D014280:Triglycerides / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D052179:Antigens, Plant; D000975:Antioxidants; D011134:Polysaccharides; D014280:Triglycerides
keywords: peach; polysaccharide; spermatogenesis