title: TiL4-Coordinated Black Phosphorus Quantum Dots as an Efficient Contrast Agent for In Vivo Photoacoustic Imaging of Cancer.
abstract: Black phosphorus quantum dots coordinated with a sulfonic ester of the titanium ligand are prepared and exhibit enhanced stability. In vitro and in vivo photoacoustic imaging applications demonstrate that the quantum dots can efficiently accumulate inside the tumor producing tumor profiles with high spatial resolution, demonstrating their potential as an efficient agent for photoacoustic imaging.
authors.affiliation: Shenzhen Key Laboratory of Two-Dimensional Materials and Devices (SKTMD), SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.|Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
authors.forename: Zhengbo
authors.initials: Z
authors.lastname: Sun
authors.affiliation: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
authors.forename: Yuetao
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, 99077, China.
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Li
authors.affiliation: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
authors.forename: Haodong
authors.initials: H
authors.lastname: Cui
authors.affiliation: Department of Radiation Therapy, Shenzhen People's Hospital, 2nd Clinical Medical Collage of Jinan University, Shenzhen, Guangdong, 518055, P. R. China.
authors.forename: Yayan
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Department of Radiation Therapy, Shenzhen People's Hospital, 2nd Clinical Medical Collage of Jinan University, Shenzhen, Guangdong, 518055, P. R. China.
authors.forename: Weihao
authors.initials: W
authors.lastname: Li
authors.affiliation: Shenzhen Key Laboratory of Two-Dimensional Materials and Devices (SKTMD), SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Tao
authors.affiliation: Shenzhen Key Laboratory of Two-Dimensional Materials and Devices (SKTMD), SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.
authors.forename: Han
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
authors.forename: Huaiyu
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, 99077, China.
authors.forename: Paul K
authors.initials: PK
authors.lastname: Chu
authors.affiliation: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.
authors.forename: Xue-Feng
authors.initials: XF
authors.lastname: Yu
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000737:chemistry*; D003952:Diagnostic Imaging; D006046:Gold / Q000737:chemistry; D006801:Humans; D008024:Ligands; D061986:MCF-7 Cells; D008297:Male; D008819:Mice, Nude; D043942:Nanotubes / Q000737:chemistry; D009369:Neoplasms / Q000175:diagnosis* / Q000473:pathology; D010758:Phosphorus / Q000737:chemistry*; D061088:Photoacoustic Techniques / Q000379:methods*; D045663:Quantum Dots / Q000737:chemistry* / Q000648:ultrastructure; D014025:Titanium
chemical_list: D003287:Contrast Media; D008024:Ligands; D010758:Phosphorus; D006046:Gold; D014025:Titanium
keywords: 2D materials; black phosphorus; near-infrared; phosphorene; photoacoustic imaging