title: Monte Carlo simulation of ruthenium eye plaques with GEANT4: influence of multiple scattering algorithms, the spectrum and the geometry on depth dose profiles.
abstract: Previous studies show remarkable differences in the simulation of electron depth dose profiles of ruthenium eye plaques. We examined the influence of the scoring and simulation geometry, the source spectrum and the multiple scattering algorithm on the depth dose profile using GEANT4. The simulated absolute dose deposition agrees with absolute dose data from the manufacturer within the measurement uncertainty. Variations in the simulation geometry as well as the source spectrum have only a small influence on the depth dose profiles. However, the multiple scattering algorithms have the largest influence on the depth dose profiles. They deposit up to 20% less dose compared to the single scattering implementation. We recommend researchers who are interested in simulating low- to medium-energy electrons to examine their simulation under the influence of different multiple scattering settings. Since the simulation and scoring geometry as well as the exact physics settings are best described by the source code of the application, we made the code publicly available.
authors.affiliation: Experimentelle Physik 5, TU Dortmund, Otto-Hahn-Str. 4, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Sommer
authors.forename: M
authors.initials: M
authors.lastname: Ebenau
authors.forename: B
authors.initials: B
authors.lastname: Spaan
authors.forename: M
authors.initials: M
authors.lastname: Eichmann
mesh_terms: D005134:Eye Neoplasms / Q000532:radiotherapy; D006801:Humans; D009010:Monte Carlo Method; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D012429:Ruthenium Radioisotopes / Q000627:therapeutic use*
chemical_list: D019275:Radiopharmaceuticals; D012429:Ruthenium Radioisotopes