title: Solely lung-involved IgG4-related disease : a case report and review of the literature.
abstract: By analyzing the clinical data of 1 case of IgG4-related lung disease(IgG4-RLD) and the review of literature, the author investigated the clinical characteristics of IgG4-RLD. IgG4-RLD is a rare disease characterized by significant elevation of serum IgG4 and infiltration of a large number of IgG4+ plasma cells. The clinical manifestations of the disease were nonspecific, and the imaging features were mixed with several types. The disease can only be involved in the lung, but also multiple organ involvement. Solely lung-involved IgG4-RD is not only extremely rare but also easily misdiagnosed as tuberculosis, lung cancer, lymphoma and other common pulmonary diseases. Histopathological examination is the key to the diagnosis of the disease. Corticosteroids are the first choice of treatment, and the overall prognosis is good.
authors.affiliation: Department of Respirology, Zhejiang Provincial People's Hospital, Hangzhou 310014, China. zhangxiaoqin197907@163.com.
authors.forename: Xiao-Qin
authors.initials: XQ
authors.lastname: Zhang
authors.forename: Guo-Ping
authors.initials: GP
authors.lastname: Chen
authors.forename: Sheng-Chang
authors.initials: SC
authors.lastname: Wu
authors.forename: Sa
authors.initials: S
authors.lastname: Yu
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
authors.forename: Xuan-Yi
authors.initials: XY
authors.lastname: Chen
authors.forename: Zhuo-Chao
authors.initials: ZC
authors.lastname: Ren
mesh_terms: D001327:Autoimmune Diseases / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D001999:Bronchoscopy; D004359:Drug Therapy, Combination; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008168:Lung / Q000187:drug effects / Q000276:immunology* / Q000473:pathology; D008171:Lung Diseases / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography; D016896:Treatment Outcome; D051598:Whole Body Imaging
chemical_list: D015415:Biomarkers; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents
keywords: IgG4-related disease; Immunoglobulin G4; Lung