title: A trombosis story and PRES.
abstract: Trombosis is seen in children with acute lymphoblastic leukemia during or after L-asparaginase treatment. Posterior reversible encephalopathy syndrome (PRES) is a complex syndrome characterized with sudden hypertension, headache, nausea, vomiting, alteration in the state of consciousness, vision defect and seizures. The cases related to this syndrome have been reportedly seen after eclampsia, organ transplantation, immunsuppressive treatments, autoimmune diseases and chemotherapy. Vasogenic edema occuring in the brain parencyhma constitues the basic pathophysiology. We present a case who developed seizures during treatment for B-cell acute lymphoblastic leukemia and diagnosed as posterior reversible encephalopathy.
authors.affiliation: Department of Pediatrics, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.
authors.forename: Vural
authors.initials: V
authors.lastname: Kartal
authors.affiliation: Department of Pediatrics, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Zara
authors.affiliation: Department of Pediatric Hematology and Oncology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.
authors.forename: Sema
authors.initials: S
authors.lastname: Yilmaz
authors.affiliation: Department of Pediatric Hematology and Oncology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.
authors.forename: Aylin
authors.initials: A
authors.lastname: Ayhan
authors.affiliation: Department of Pediatric Hematology and Oncology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.
authors.forename: Asim
authors.initials: A
authors.lastname: Yoruk
authors.affiliation: Department of Pediatric Hematology and Oncology, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.
authors.forename: Cetin
authors.initials: C
authors.lastname: Timur
keywords: Child; L-asparaginase; PRES; leukemia; thrombosis