title: Fast Optimization of LiMgMnOx/La2O3Catalysts for the Oxidative Coupling of Methane.
abstract: The development of efficient catalyst for oxidative coupling of methane (OCM) reaction represents a grand challenge in direct conversion of methane into other useful products. Here, we reported that a newly developed combinatorial approach can be used for ultrafast optimization of La2O3-based multicomponent metal oxide catalysts in OCM reaction. This new approach integrated inkjet printing assisted synthesis (IJP-A) with multidimensional group testing strategy (m-GT) tactfully takes the place of conventionally high-throughput synthesis-and-screen experiment. Just within a week, 2048 formulated LiMgMnOx-La2O3catalysts in a 64·8·8·8·8 = 262 144 compositional space were fabricated by IJP-A in a four-round synthesis-and-screen process, and an optimized formulation has been successfully identified through only 4·8 = 32 times of tests via m-GT screening strategy. The screening process identifies the most promising ternary composition region is Li0-0.48Mg0-6.54Mn0-0.62-La100Oxwith an external C2yield of 10.87% at 700 °C. The yield of C2is two times as high as the pure nano-La2O3. The good performance of the optimized catalyst formulation has been validated by the manual preparation, which further prove the effectiveness of the new combinatorial methodology in fast discovery of heterogeneous catalyst.
authors.affiliation: Department of Chemistry, Zhejiang University , HangZhou 310027, China.
authors.forename: Zhinian
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Chemistry, Zhejiang University , HangZhou 310027, China.
authors.forename: Lei
authors.initials: L
authors.lastname: He
authors.affiliation: Department of Chemistry, Zhejiang University , HangZhou 310027, China.
authors.forename: Shenliang
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Chemistry, Zhejiang University , HangZhou 310027, China.
authors.forename: Wuzhong
authors.initials: W
authors.lastname: Yi
authors.affiliation: Department of Chemistry, Zhejiang University , HangZhou 310027, China.
authors.forename: Shihui
authors.initials: S
authors.lastname: Zou
authors.affiliation: Department of Chemistry, Zhejiang University , HangZhou 310027, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Xiao
authors.affiliation: Department of Chemistry, Zhejiang University , HangZhou 310027, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Fan
mesh_terms: D002384:Catalysis; D057166:High-Throughput Screening Assays; D007202:Indicators and Reagents; D007281:Ink; D007811:Lanthanum / Q000737:chemistry*; D017895:Manganese Compounds / Q000737:chemistry; D008697:Methane / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D058451:Oxidative Coupling; D010087:Oxides / Q000737:chemistry*; D011327:Printing; D014961:X-Ray Diffraction
chemical_list: D007202:Indicators and Reagents; D017895:Manganese Compounds; D010087:Oxides; C103829:lanthanum oxide; D007811:Lanthanum; D008697:Methane
keywords: high-throughput; inkjet printing; multidimensional group testing; oxidative coupling of methane