title: Genetic characterisation of novel, highly pathogenic avian influenza (HPAI) H5N6 viruses isolated in birds, South Korea, November 2016.
abstract: A novel genotype of H5N6 influenza viruses was isolated from migratory birds in South Korea during November 2016. Domestic outbreaks of this virus were associated with die-offs of wild birds near reported poultry cases in Chungbuk province, central South Korea. Genetic analysis and animal studies demonstrated that the Korean H5N6 viruses are highly pathogenic avian influenza (HPAI) viruses and that these viruses are novel reassortants of at least three different subtypes (H5N6, H4N2 and H1N1).
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.|These authors contributed equally to this work.
authors.forename: Young-Jae
authors.initials: YJ
authors.lastname: Si
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.|These authors contributed equally to this work.
authors.forename: In Won
authors.initials: IW
authors.lastname: Lee
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Eun-Ha
authors.initials: EH
authors.lastname: Kim
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Young-Il
authors.initials: YI
authors.lastname: Kim
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Hyeok-Il
authors.initials: HI
authors.lastname: Kwon
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Su-Jin
authors.initials: SJ
authors.lastname: Park
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Hiep Dinh
authors.initials: HD
authors.lastname: Nguyen
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Se Mi
authors.initials: SM
authors.lastname: Kim
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Jin-Jung
authors.initials: JJ
authors.lastname: Kwon
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Won-Suk
authors.initials: WS
authors.lastname: Choi
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Yun Hee
authors.initials: YH
authors.lastname: Beak
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Min-Suk
authors.initials: MS
authors.lastname: Song
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
authors.forename: Chul-Joong
authors.initials: CJ
authors.lastname: Kim
authors.affiliation: Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Webby
authors.affiliation: College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
authors.forename: Young-Ki
authors.initials: YK
authors.lastname: Choi
mesh_terms: D000818:Animals; D000835:Animals, Wild / Q000821:virology*; D001717:Birds / Q000821:virology*; D004196:Disease Outbreaks / Q000662:veterinary; D005838:Genotype; D053118:Influenza A Virus, H1N1 Subtype / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity*; D005585:Influenza in Birds / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology*; D010802:Phylogeny; D011200:Poultry / Q000821:virology; D011201:Poultry Diseases / Q000453:epidemiology; D056910:Republic of Korea / Q000453:epidemiology; D017422:Sequence Analysis, DNA
keywords: H5N6; Highly pathogenic avian influenza (HPAI); Influenza A virus; South Korea