title: Life-Threatening Ventricular Arrhythmia and Brugada-Type ST-Segment Elevation Associated With Acute Ischemia of the Right Ventricular Outflow Tract.
abstract: Brugada-type ECG (Br-ECG) is occasionally observed during acute myocardial ischemia of the right ventricular outflow tract (RVOT). No studies have explored, however, the association of ventricular tachyarrhythmia and development of Br-ECG due to acute ischemia of the RVOT.
  
  
  
  The study included 13 consecutive patients with acute ischemia of the RVOT during coronary catheterization. Patients were divided into 2 groups: those with Br-ECG (group B) and those without (group N). The proportion of male patients was higher in group B than in group N (100% vs. 25%, P<0.01), and VT/VF developed in only patients with Br-ECG (group B). In group B, VT/VF was observed in patients without pre-existing organic change in the conus/right ventricular (RV) branch of the right coronary artery and no VT/VF was seen in patients with organic coronary stenosis despite Br-ECG.
  
  
  
  Acute myocardial ischemia of the RVOT caused Br-ECG predominantly in male patients and subsequent development of VT/VF in some patients. VT/VF was seen in patients without any obstructive lesion but arrhythmic events were not observed in RVOT ischemia in the case of pre-existing coronary occlusion or stenosis of the conus or RV branch, suggesting the effects of precondition.
authors.affiliation: Department of Cardiology, Yokohama Minami Kyosai Hospital.
authors.forename: Rena
authors.initials: R
authors.lastname: Nakamura
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Nishizaki
authors.forename: Kiko
authors.initials: K
authors.lastname: Lee
authors.forename: Masato
authors.initials: M
authors.lastname: Shimizu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fujii
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Yamawake
authors.forename: Harumizu
authors.initials: H
authors.lastname: Sakurada
authors.forename: Masayasu
authors.initials: M
authors.lastname: Hiraoka
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Isobe
mesh_terms: D000368:Aged; D053840:Brugada Syndrome / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D023921:Coronary Stenosis / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D003331:Coronary Vessels / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000503:physiopathology / Q000601:surgery