title: B-Cell Lymphoma in a Patient With a History of Foreign Body Injection.
abstract: Dermal filler injection has been one of the most evolving areas of interest in the field of esthetic plastic surgery. This procedure is sometimes preferred to surgery due to shorter procedure and patient recovery times, and because it is suitable for a wide range of applications. Dermal filler injection is considered to be relatively safe, but various late complications such as infection and foreign body granuloma sometimes occur. Postprocedure development of lymphoma also occurs, but is extremely rare. The authors diagnosed extranodal marginal zone B-cell lymphoma of the mucosa associated lymphoid tissue that developed after a filler injection procedure was performed on a patient's face. This 72-year-old female first presented with a palpable mass on her left cheek that developed after a probable silicone injection. An magnetic resonance imaging (MRI) scan and excisional biopsy confirmed the presence of the lymphoma. Complete remission occurred after radiotherapy. This rare case of lymphoma in a patient with a history of foreign body injection indicated that practitioners must be aware that long-standing chronic inflammation resulting from dermal filler injections can trigger lymphoma development.
authors.affiliation: *Department of Plastic and Reconstructive Surgery, Gachon University Gil Medical Center †Department of Pathology, Gachon University Gil Medical Center, Namdong-gu, Republic of Korea.
authors.forename: Seo Hyung
authors.initials: SH
authors.lastname: Lee
authors.forename: Hyun Chul
authors.initials: HC
authors.lastname: Kim
authors.forename: Yu Jin
authors.initials: YJ
authors.lastname: Kim
mesh_terms: D000368:Aged; D002610:Cheek / Q000473:pathology; D000067548:Dermal Fillers / Q000009:adverse effects*; D005153:Facial Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000532:radiotherapy; D005260:Female; D015745:Granuloma, Foreign-Body / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D007267:Injections; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000209:etiology* / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D012074:Remission Induction
chemical_list: D000067548:Dermal Fillers