title: Direct α-Arylation/Heteroarylation of 2-Trifluoroboratochromanones via Photoredox/Nickel Dual Catalysis.
abstract: Utilizing photoredox/nickel dual catalysis, diverse flavanones have been synthesized by coupling novel 2-trifluoroboratochromanone building blocks with aryl and heteroaryl bromide partners. The newly reported trifluoroboratochromanones can be easily accessed from the corresponding chromones on multigram scale. This represents a general route for accessing natural and unnatural flavanones that were previously formed through a synthetically more restrictive ring closure route from chalcone precursors.
authors.affiliation: Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
authors.forename: Jennifer K
authors.initials: JK
authors.lastname: Matsui
authors.affiliation: Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
authors.forename: Gary A
authors.identifier: 0000-0002-9114-5584
authors.initials: GA
authors.lastname: Molander
mesh_terms: D002384:Catalysis; D017611:Fluorine Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel; D010084:Oxidation-Reduction
chemical_list: D017611:Fluorine Compounds; D009532:Nickel