title: Systemic Sclerosis Sine Scleroderma in Mexican Patients. Case Reports.
abstract: Systemic sclerosis sine scleroderma (ssSSc) is a form of systemic sclerosis that is characterized by Raynaud's phenomenon (RP), visceral involvement without thickening of skin and anticentromere antibodies (ACA). We studied 10 ssSsc patients with a prevalence of 2%. The clinical signs were: RP 9/10, esophageal manifestations 8/10, pulmonary arterial hypertension 4/10, interstitial lung disease 4/10, cardiac signs 3/10 and ACA 8/10.
  
  
  CONCLUSIONS
  In patients with RP, esophageal dysmotility, interstitial lung disease and pulmonary arterial hypertension should be tested for ACA in order to establish a prompt diagnosis and treatment of ssSSc.
authors.affiliation: Departamento de Medicina Interna, Unidad Médica de Alta Especialidad, Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional, La Raza, Instituto Mexicano del Seguro Social, México D.F., México; División de Estudios de posgrado, Facultad de Medicina, Universidad Nacional Autónoma de México, México D.F., México. Electronic address: Olgavera62@yahoo.com.mx.
authors.forename: Olga
authors.initials: O
authors.lastname: Vera-Lastra
authors.affiliation: Universidad Autónoma de Sinaloa, México; Academia Mexicana de la Ciencia, México.
authors.forename: Christian Alexis
authors.initials: CA
authors.lastname: Sauceda-Casas
authors.affiliation: División de Estudios de posgrado, Facultad de Medicina, Universidad Nacional Autónoma de México, México D.F., México; División de Investigación en Salud, Unidad Médica de Alta Especialidad, Hospital de Especialidades, Dr. Antonio Fraga Mouret, Centro Médico Nacional, La Raza. Instituto Mexicano del Seguro Social, México D.F., México.
authors.forename: María Del Pilar Cruz
authors.initials: MDPC
authors.lastname: Domínguez
authors.affiliation: Departamento de Medicina Interna, Unidad Médica de Alta Especialidad, Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional, La Raza, Instituto Mexicano del Seguro Social, México D.F., México; División de Estudios de posgrado, Facultad de Medicina, Universidad Nacional Autónoma de México, México D.F., México.
authors.forename: Sergio Alberto Mendoza
authors.initials: SAM
authors.lastname: Alvarez
authors.affiliation: Departamento de Medicina Interna, Unidad Médica de Alta Especialidad, Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional, La Raza, Instituto Mexicano del Seguro Social, México D.F., México.
authors.forename: Jesús
authors.initials: J
authors.lastname: Sepulceda-Delgado
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D012189:Retrospective Studies; D012595:Scleroderma, Systemic / Q000150:complications / Q000175:diagnosis* / Q000473:pathology
keywords: Clinical manifestations; Esclerosis sistémica sin esclerodermia; Manifestaciones clínicas; Prevalence; Prevalencia; Systemic sclerosis sine scleroderma