title: Urine Output during Cardiopulmonary Bypass Predicts Acute Kidney Injury after Coronary Artery Bypass Grafting.
abstract: This study evaluated the relationship between the amount of urinary output during cardiopulmonary bypass and acute kidney injury in the postoperative period of coronary artery bypass grafting.
  
  
  
  Two hundred patients with normal preoperative serum creatinine levels, operated on with isolated CABG between 2012-2014 were investigated retrospectively. The RIFLE (Risk, injury, failure, loss of function, and end-stage renal disease) risk scores were calculated for each patient in the third postoperative day. Patients were distributed into two groups in relation to the presence of acute kidney injury or not and these two groups were compared.
  
  
  
  The urinary output (mL/kg/hour) during cardiopulmonary bypass in the acute kidney injury negative group was significantly higher than in the acute kidney injury positive group (P = .022). In case of a urinary output value 3.70 and lower to predict acute kidney injury positivity, sensitivity was detected as 71.43%. Results of the analysis for urinary output predict positivity of acute kidney injury.
  
  
  
  We suggest that urine output during cardiopulmonary bypass is a significant criteria that could predict acute kidney injury following coronary artery bypass grafting with cardiopulmonary bypass. Attempts to increase the urine output during cardiopulmonary bypass could help to maintain the renal functions during and after surgery.
authors.affiliation: Department of Anesthesiology and Reanimation, Derince Research and Education Hospital Kocaeli, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yilmaz
authors.affiliation: Department of Cardiovascular Surgery, Derince Research and Education Hospital Kocaeli, Turkey.
authors.forename: Rezan
authors.initials: R
authors.lastname: Aksoy
authors.affiliation: Anesthesiology and Reanimation Department, Kocaeli State Hospital, Kocaeli, Turkey.
authors.forename: Vildan
authors.initials: V
authors.lastname: Kilic Yilmaz
authors.affiliation: Department of Anesthesiology and Reanimation, Derince Research and Education Hospital Kocaeli, Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Balci
authors.affiliation: Department of Cardiovascular Surgery, Derince Research and Education Hospital Kocaeli, Turkey.
authors.forename: Cagri
authors.initials: C
authors.lastname: Duzyol
authors.affiliation: Department of Cardiovascular Surgery, Derince Research and Education Hospital Kocaeli, Turkey.
authors.forename: Atike
authors.initials: A
authors.lastname: Tekeli Kunt
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology / Q000209:etiology / Q000652:urine*; D000368:Aged; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D003324:Coronary Artery Disease / Q000378:metabolism / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D015994:Incidence; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D014421:Turkey / Q000453:epidemiology; D014554:Urination / Q000502:physiology*