title: Functional Connectomics: How Maggots Make Up Their Minds.
abstract: How Drosophila larvae select one behavior or a sequence of behaviors, and then persist in the final one, has been addressed by a powerful combination of electron-microscopy reconstruction of neuronal connections, genetic manipulations, electrophysiology, and neuronal modeling. Surprisingly, reciprocal inhibitory synaptic connections are major players in choosing, sequencing and maintaining behaviors.
authors.affiliation: Neurobiology Section, Department of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0357, USA. Electronic address: wkristan@ucsd.edu.
authors.forename: William B
authors.initials: WB
authors.lastname: Kristan
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D063132:Connectome / Q000379:methods*; D004330:Drosophila / Q000166:cytology / Q000254:growth & development* / Q000502:physiology* / Q000648:ultrastructure; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D007814:Larva / Q000166:cytology / Q000502:physiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009474:Neurons / Q000166:cytology / Q000502:physiology* / Q000648:ultrastructure; D013569:Synapses / Q000502:physiology / Q000648:ultrastructure
chemical_list: D029721:Drosophila Proteins