title: Transcatheter aortic valve implantation with the Edwards Sapien 3 valve: First experiences in Turkey.
abstract: OBJECTIVE
  Transcatheter aortic valve implantation (TAVI) has shown promising results in patients with severe aortic stenosis (AS) at high risk for open heart surgery. We aimed to evaluate outcomes of patients who underwent TAVI with Edwards SAPIEN 3 Transcatheter Heart Valve (S3), a second-generation TAVI device.
  
  
  METHODS
  Between November 2014 and June 2016, 31 high-risk patients received balloon-expandable S3 valve at Atatürk Training and Research Hospital that has the largest case series in Turkey.
  
  
  RESULTS
  Mean age of the patients was 76.1±12.6 years. Mean Society of Thoracic Surgeons and logistic European System for Cardiac Operative Risk Evaluation scores were 7.8%±3.1 and 31.4%±17.6, respectively. S3 valve was implanted in 27 patients via transfemoral approach and via trans-subclavian approach in 4 patients under local (n=29) or general (n=2) anesthesia. Procedural success rate was 100% (23 mm, n=7; 26 mm, n=16; 29 mm, n=8). Paravalvular aortic regurgitation (PAR) was absent or trivial in 29 (93.6%) patients and mild in 2 (6.4%) patients. Permanent pacemaker implantation (PPI) was required in 2 (6.4%) patients during the procedure, and in-hospital mortality occurred in 1 (3.2%) of those 2 patients.
  
  
  CONCLUSIONS
  S3 valve is associated with higher rate of device success and lower incidence of PAR, peripheral vascular complications, and need for new PPI.
authors.affiliation: Department of Cardiology, Atatürk Training and Research Hospital, Ankara, Turkey. drnabiaslan@hotmail.com.
authors.forename: Abdullah Nabi
authors.initials: AN
authors.lastname: Aslan
authors.forename: Serdal
authors.initials: S
authors.lastname: Baştuğ
authors.forename: Hacı Ahmet
authors.initials: HA
authors.lastname: Kasapkara
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Ayhan
authors.forename: Hakan
authors.initials: H
authors.lastname: Süygün
authors.forename: Telat
authors.initials: T
authors.lastname: Keleş
authors.forename: Tahir
authors.initials: T
authors.lastname: Durmaz
authors.forename: Nihal
authors.initials: N
authors.lastname: Akar Bayram
authors.forename: Emine
authors.initials: E
authors.lastname: Bilen
authors.forename: Engin
authors.initials: E
authors.lastname: Bozkurt
mesh_terms: D000368:Aged; D001021:Aortic Valve; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000601:surgery*; D006328:Cardiac Catheterization; D004867:Equipment Design; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014421:Turkey