title: Recrudescence ofPlasmodium falciparumin a Primigravida After Nearly 3 Years of Latency.
abstract: We present a case of a primigravid woman who presented withPlasmodium falciparumnearly 3 years after she last visited a malaria-endemic region. We review the literature to identify case reports of recrudescentP. falciparummalaria during pregnancy, including those with prolonged latency. Reports of recrudescence ofP. falciparumduring pregnancy are limited.Plasmodium falciparuminfection can persist for years. Recrudescence can occur with waning of immunity following departure from endemic areas. Pregnancy, particularly the primigravid state, is a risk factor for severe infection.
authors.affiliation: University of Massachusetts Medical School, Worcester, Massachusetts.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al Hammadi
authors.affiliation: University of Massachusetts Medical School, Worcester, Massachusetts.
authors.forename: Michael
authors.initials: M
authors.lastname: Mitchell
authors.affiliation: Saint Vincent Hospital, Worcester, Massachusetts.
authors.forename: George M
authors.initials: GM
authors.lastname: Abraham
authors.affiliation: University of Massachusetts Medical School, Worcester, Massachusetts.
authors.forename: Jennifer P
authors.initials: JP
authors.lastname: Wang
mesh_terms: D061605:Administration, Intravenous; D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use; D018890:Chemoprevention; D002738:Chloroquine / Q000627:therapeutic use; D005260:Female; D020073:Gravidity; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis* / Q000188:drug therapy; D010963:Plasmodium falciparum / Q000302:isolation & purification*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis* / Q000188:drug therapy; D011802:Quinidine / Q000627:therapeutic use; D012008:Recurrence; D012307:Risk Factors
chemical_list: D000962:Antimalarials; D002738:Chloroquine; D011802:Quinidine