title: Use of intravenous immunoglobulin therapy for myositis: an audit in South Australian patients.
abstract: In South Australia, between 2000 and 2014, 57 patients with idiopathic inflammatory myositis (IIM) were treated with intravenous immunoglobulin (IVIg). We reviewed disease characteristics to determine predictors of response to therapy and IVIg dosing and duration to identify opportunities to rationalise IVIg use. Patients with dermatomyositis/polymyositis had a response rate of 77% and were more likely than inclusion body myositis to respond to therapy. Consideration should be given to the use of the lowest possible dose of IVIg and to the undertaking of trials of cessation of IVIg in patients with stable IIM.
authors.affiliation: Immunology Department, SA Pathology Flinders Medical Centre, Adelaide, South Australia, Australia.|Immunology Department, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors.forename: Caroline
authors.initials: C
authors.lastname: Foreman
authors.affiliation: Immunology Department, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors.forename: Paul
authors.initials: P
authors.lastname: Russo
authors.affiliation: Immunoglobulin Governance, SA Health, Adelaide, South Australia, Australia.
authors.forename: Noelene
authors.initials: N
authors.lastname: Davies
authors.affiliation: Immunology Department, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors.forename: Pravin
authors.initials: P
authors.lastname: Hissaria
authors.affiliation: Rheumatology Department, Royal Adelaide Hospital, Adelaide, South Australia, Australia.|Discipline of Medicine, Adelaide University, Adelaide, South Australia, Australia.
authors.forename: Susanna
authors.initials: S
authors.lastname: Proudman
authors.affiliation: Immunology Department, SA Pathology Flinders Medical Centre, Adelaide, South Australia, Australia.
authors.forename: Tiffany
authors.initials: T
authors.lastname: Hughes
authors.affiliation: Rheumatology Department, Royal Adelaide Hospital, Adelaide, South Australia, Australia.|Discipline of Medicine, Adelaide University, Adelaide, South Australia, Australia.
authors.forename: Vidya
authors.initials: V
authors.lastname: Limaye
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003882:Dermatomyositis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D018979:Myositis, Inclusion Body / Q000188:drug therapy*; D013021:South Australia; D055815:Young Adult
chemical_list: D016756:Immunoglobulins, Intravenous
keywords: dermatomyositis; idiopathic inflammatory myopathy; inclusion body myositis; intravenous immunoglobulin; polymyositis