title: Acinar Adenocarcinoma of Prostate with Predominant Ttf-1 Positive Intraductal Component.
abstract: Intraductal carcinoma of prostate has been previously described in radical prostatectomies. It's rarely encountered in needle biopsies in the absence of infiltrative carcinoma. But, both histogenesis and nomenclature of the lesion is still controversial. Among the pure intraductal carcinoma of prostate cases, a different solid patern was described with smaller nuclei at the center of the ducts. However, there is a lack of information about the association of those cases with acinar prostate adenocarcinoma. Herein, we describe a case of acinar adenocarcinoma with predominant non-neuroendocrine TTF-1 positive small cell intraductal component.
authors.affiliation: Department of Pathology, Ege University, Faculty of Medicine, İZMİR, TURKEY.
authors.forename: Banu
authors.initials: B
authors.lastname: Sarsik
authors.forename: Nisar
authors.initials: N
authors.lastname: Karadeniz
authors.forename: Adnan
authors.initials: A
authors.lastname: Şimşir
authors.forename: Rahmi
authors.initials: R
authors.lastname: Akyol
authors.forename: Kutsal
authors.initials: K
authors.lastname: Yörükoğlu
authors.forename: Sait
authors.initials: S
authors.lastname: Şen
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D018267:Carcinoma, Acinar Cell / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D004268:DNA-Binding Proteins / Q000032:analysis / Q000096:biosynthesis*; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D014157:Transcription Factors
chemical_list: D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins; C504003:TTF1 protein, human; D014157:Transcription Factors