title: Push-pull strategy in the regulation of postembryonic root development.
abstract: Unlike animals, plants continue to grow throughout their lives. The stem cell niche, protected in meristems of shoots and roots, enables this process. In the root, stem cells produce precursors for highly organized cell types via asymmetric cell divisions. These precursors, which are "transit-amplifying cells," actively divide for several rounds before entering into differentiation programs. In this review, we highlight positive feedback regulation between shoot- and root-ward signals during the postembryonic root growth, which is reminiscent of a "push-pull strategy" in business parlance. This property of molecular networks underlies the regulation of stem cells and their organizer, the "quiescent center," as well as of the signaling between stem cell niche, transit-amplifying cells, and beyond.
authors.affiliation: School of Biological Sciences, College of Natural Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.
authors.forename: Goh
authors.initials: G
authors.lastname: Choe
authors.affiliation: School of Biological Sciences, College of Natural Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea; Plant Genomics and Breeding Institute, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea. Electronic address: jl924@snu.ac.kr.
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Lee
mesh_terms: D060049:Asymmetric Cell Division; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D018519:Meristem / Q000254:growth & development; D018517:Plant Roots / Q000254:growth & development*; D018520:Plant Shoots / Q000254:growth & development*; D055153:Stem Cell Niche; D013234:Stem Cells / Q000378:metabolism