title: Cardiovascular diseases: Interplay of epigenetics.
abstract: Several association studies have been carried out to elucidate the role of genetic variants in cardiovascular diseases (CVDs), while studies on the epigenome regulating gene expression changes are helping to understand the development of disease and factors promoting such changes. This review summarizes the different epigenetic aspects involved in cardiac development and disease along with current therapeutic interventions.
authors.affiliation: a Department of Genetics and Molecular Medicine , Vasavi Medical and Research Center , Hyderabad , India.
authors.forename: Yog R
authors.initials: YR
authors.lastname: Ahuja
authors.affiliation: b Department of Clinical Pharmacology , Apollo Hospital, Jubilee Hills , Hyderabad , India.
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Sharma
authors.affiliation: a Department of Genetics and Molecular Medicine , Vasavi Medical and Research Center , Hyderabad , India.|c Research Unit, Hansgene Cancer Foundation , Hyderabad , India.
authors.forename: Vasavi
authors.initials: V
authors.lastname: Mohan
mesh_terms: D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000235:genetics* / Q000517:prevention & control; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D015870:Gene Expression; D006657:Histones / Q000235:genetics; D006801:Humans; D022661:RNA, Untranslated / Q000235:genetics
chemical_list: D006657:Histones; D022661:RNA, Untranslated
keywords: Cardiovascular disease; epigenetic; factors; therapeutic