title: Valuable building block for the synthesis of lunularic acid, hydrangeic acid and their analogues.
abstract: A new functionalised sulphone-based building block has been synthesised that enabled C-C bond formation through Julia olefination. The utility of developed building block was demonstrated by successful synthesis of two natural products lunularic acid, hydrangeic acid and initial libraries of their analogues.
authors.affiliation: a Department of Chemistry , Indian Institute of Technology Madras , Chennai , India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Mukkamala
authors.affiliation: a Department of Chemistry , Indian Institute of Technology Madras , Chennai , India.
authors.forename: Asik
authors.initials: A
authors.lastname: Hossain
authors.affiliation: a Department of Chemistry , Indian Institute of Technology Madras , Chennai , India.
authors.forename: Indrapal
authors.initials: I
authors.lastname: Singh Aidhen
mesh_terms: D012459:Salicylates / Q000138:chemical synthesis*; D013267:Stilbenes / Q000138:chemical synthesis*; D013450:Sulfones / Q000737:chemistry*
chemical_list: D012459:Salicylates; D013267:Stilbenes; D013450:Sulfones; C543195:hydrangeic acid; C067452:lunularic acid
keywords: Julia olefination; Lunularic acid; amorfrutin; bi-benzyl natural products; cajaninstilbene acid; hydrangeic acid