title: [Ultrastructural alterations in renal biopsy leading to the diagnosis of HIV infection].
abstract: HIV infection has different clinical presentations. We report a 21-year-old male with longstanding isolated microscopic hematuria attributed to thin glomerular basement membrane disease, who after 15 years of follow-up presented with significant proteinuria. A kidney biopsy was performed, revealing the presence of tubulo-reticular inclusions in the glomerular endothelial cells. This finding led to suspect an HIV infection, which was verified. Antiretroviral therapy, angiotensin-converting enzyme and angiotensin II receptor blockers were prescribed. At 6 years of diagnosis the patient is asymptomatic and has normal kidney function. Microscopic hematuria and low level proteinuria persists.
authors.affiliation: Sección Nefrología, Servicio de Medicina, Hospital Naval A. Nef, Viña del Mar, Chile.
authors.forename: Jorge
authors.initials: J
authors.lastname: Vega
authors.affiliation: Escuela de Medicina, Sede Viña del Mar, Universidad Andrés Bello, Viña del Mar, Chile.
authors.forename: M Elizabeth
authors.initials: ME
authors.lastname: Barthel
authors.affiliation: Departamento de Anatomía Patológica, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Gonzalo P
authors.initials: GP
authors.lastname: Méndez
mesh_terms: D016263:AIDS-Associated Nephropathy / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D001706:Biopsy; D006417:Hematuria / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007684:Kidney Tubules / Q000648:ultrastructure; D008297:Male; D011507:Proteinuria / Q000652:urine; D013997:Time Factors; D055815:Young Adult