title: Risk of developing palatally displaced canines in patients with early detectable dental anomalies: a retrospective cohort study.
abstract: OBJECTIVE
  To estimate the risk of PDC occurrence in children with dental anomalies identified early during mixed dentition.
  
  
  METHODS
  The sample comprised 730 longitudinal orthodontic records from children (448 females and 282 males) with an initial mean age of 8.3 years (SD=1.36). The dental anomaly group (DA) included 263 records of patients with at least one dental anomaly identified in the initial or middle mixed dentition. The non-dental anomaly group (NDA) was composed of 467 records of patients with no dental anomalies. The occurrence of PDC in both groups was diagnosed using panoramic and periapical radiographs taken in the late mixed dentition or early permanent dentition. The prevalence of PDC in patients with and without early diagnosed dental anomalies was compared using the chi-square test (p<0.01), relative risk assessments (RR), and positive and negative predictive values (PPV and NPV).
  
  
  RESULTS
  PDC frequency was 16.35% and 6.2% in DA and NDA groups, respectively. A statistically significant difference was observed between groups (p<0.01), with greater risk of PDC development in the DA group (RR=2.63). The PPV and NPV was 16% and 93%, respectively. Small maxillary lateral incisors, deciduous molar infraocclusion, and mandibular second premolar distoangulation were associated with PDC.
  
  
  CONCLUSIONS
  Children with dental anomalies diagnosed during early mixed dentition have an approximately two and a half fold increased risk of developing PDC during late mixed dentition compared with children without dental anomalies.
authors.affiliation: - Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Odontopediatria, Ortodontia e Saúde Coletiva; Hospital de Reabilitação de Anomalias Craniofaciais, Bauru, SP, Brasil.
authors.forename: Daniela Gamba
authors.initials: DG
authors.lastname: Garib
authors.affiliation: - Universidade de São Paulo, Hospital de Reabilitação de Anomalias Craniofaciais, Bauru, SP, Brasil.
authors.forename: Melissa
authors.initials: M
authors.lastname: Lancia
authors.affiliation: - Universidade de São Paulo, Hospital de Reabilitação de Anomalias Craniofaciais, Bauru, SP, Brasil.
authors.forename: Renata Mayumi
authors.initials: RM
authors.lastname: Kato
authors.affiliation: - Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Odontopediatria, Ortodontia e Saúde Coletiva; Hospital de Reabilitação de Anomalias Craniofaciais, Bauru, SP, Brasil.
authors.forename: Thais Marchini
authors.initials: TM
authors.lastname: Oliveira
authors.affiliation: - Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Ciências Biológicas; Hospital de Reabilitação de Anomalias Craniofaciais, Bauru, SP, Brasil.
authors.forename: Lucimara Teixeira das
authors.initials: LT
authors.lastname: Neves
mesh_terms: D001938:Brazil / Q000453:epidemiology; D002648:Child; D003481:Cuspid / Q000002:abnormalities* / Q000000981:diagnostic imaging; D003818:Dentition, Mixed; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008437:Maxilla / Q000002:abnormalities; D015995:Prevalence; D011862:Radiography, Panoramic; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D017678:Sex Distribution; D014071:Tooth Abnormalities / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology; D014079:Tooth Eruption, Ectopic / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D014095:Tooth, Impacted / Q000209:etiology