title: Multilocular Cystic Renal Cell Carcinoma or Cystic Nephroma?
abstract: The incidence of Multilocular cystic renal cell carcinoma (MCRCC) in literature is very low and confounding MCRCC with cystic nephroma (CN) is even more unusual. The aim of this report is to present a case of MCRCC and emphasize the importance of the preoperative radiologic evaluation and immunohistochemical staining confirmation to obtain an accurate diagnosis. A 73-year-old woman presented with a history of 4-month right flank pain. CT showed a Bosniak type III renal mass. After laparoscopic partial nephrectomy the initial report was cystic nephroma. Immunohistochemical staining was performed being positive for Epithelial Membrane Antigen thus changing the diagnosis to MCRCC. Multilocular cystic renal cell carcinoma cannot reliably be distinguished from cystic nephroma neither by physical examination nor by radiologic evaluation; immunohistochemical staining assay is useful to differentiate between these conditions allowing an accurate diagnosis and proper follow-up.
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Adolfo
authors.identifier: 0000-0002-7823-1664
authors.initials: A
authors.lastname: González-Serrano
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Roberto
authors.initials: R
authors.lastname: Cortez-Betancourt
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Alías-Melgar
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Pedro Jair
authors.initials: PJ
authors.lastname: Botello-Gómez
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Emilio
authors.initials: E
authors.lastname: Ramírez-Garduño
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Eric Iván
authors.initials: EI
authors.lastname: Trujillo-Vázquez
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Yosimart
authors.initials: Y
authors.lastname: Torres-Santos
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Mata-Martínez
authors.affiliation: Department of Urology, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
authors.forename: Fernando
authors.initials: F
authors.lastname: Carreño-de la Rosa