title: MIS Score: Prediction Model for Minimally Invasive Surgery.
abstract: BACKGROUND
  Reports suggest that patients with spontaneous intracerebral hemorrhage (ICH) can benefit from minimally invasive surgery, but the inclusion criterion for operation is controversial. This article analyzes factors affecting the 30-day prognoses of patients who have received minimally invasive surgery and proposes a simple grading scale that represents clinical operation effectiveness.
  
  
  METHODS
  The records of 101 patients with spontaneous ICH presenting to Qianfoshan Hospital were reviewed. Factors affecting their 30-day prognosis were identified by logistic regression. A clinical grading scale, the MIS score, was developed by weighting the independent predictors based on these factors.
  
  
  RESULTS
  Univariate analysis revealed that the factors that affect 30-day prognosis include Glasgow coma scale score (P < 0.01), age ≥80 years (P < 0.05), blood glucose (P < 0.01), ICH volume (P < 0.01), operation time (P < 0.05), and presence of intraventricular hemorrhage (P < 0.001). Logistic regression revealed that the factors that affect 30-day prognosis include Glasgow coma scale score (P < 0.05), age (P < 0.05), ICH volume (P < 0.01), and presence of intraventricular hemorrhage (P < 0.05). The MIS score was developed accordingly; 39 patients with 0-1 MIS scores had favorable prognoses, whereas only 9 patients with 2-5 MIS scores had poor prognoses.
  
  
  CONCLUSIONS
  The MIS score is a simple grading scale that can be used to select patients who are suited for minimal invasive drainage surgery. When MIS score is 0-1, minimal invasive surgery is strongly recommended for patients with spontaneous cerebral hemorrhage. The scale merits further prospective studies to fully determine its efficacy.
authors.affiliation: Department of Neurosurgery, Qianfoshan Hospital affiliated to Shandong University, Jinan, Shandong, People's Republic of China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Shandong University, Jinan, Shandong, People's Republic of China.
authors.forename: Jingwei
authors.initials: J
authors.lastname: Cao
authors.affiliation: Department of Neurosurgery, Qianfoshan Hospital affiliated to Shandong University, Jinan, Shandong, People's Republic of China.
authors.forename: Xianzeng
authors.initials: X
authors.lastname: Hou
authors.affiliation: Department of Neurosurgery, Qianfoshan Hospital affiliated to Shandong University, Jinan, Shandong, People's Republic of China. Electronic address: huyy009@hotmail.com.
authors.forename: Guangcun
authors.initials: G
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000601:surgery*; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D003661:Decision Support Techniques; D004322:Drainage / Q000379:methods*; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D007223:Infant; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D019635:Neurosurgical Procedures / Q000379:methods; D061646:Operative Time; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D014207:Trephining / Q000379:methods*; D055815:Young Adult
chemical_list: D001786:Blood Glucose
keywords: Cerebral hemorrhage; Minimal invasive surgery; Prognostic factors; Scale