title: Bilateral Papillophlebitis in a Patient with Mutation of Metilenetetrahydrofolate Reductase Enzyme.
abstract: Papillophlebitis is known as central retinal vein occlusion seen in young patients. It usually presents as unilateral optic disc edema with cotton wool spots and hemorrhage in the peripapillary region. As it may be due to many autoimmune and inflammatory causes, a thorough systemic evaluation of the patient is warranted. In this case report we describe a bilateral, simultaneous papillophlebitis case thought to be related to hyperhomocysteinemia secondary to C677T polymorphism of methylenetetrahyrofolate reductase enzyme.
authors.affiliation: Tatvan State Hospital, Ophthalmology Clinic, Bitlis, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Güzel
authors.affiliation: Selçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
authors.forename: Banu
authors.initials: B
authors.lastname: Turgut Öztürk
authors.affiliation: Selçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
authors.forename: Şansal
authors.initials: Ş
authors.lastname: Gedik
authors.affiliation: Selçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
authors.forename: Berker
authors.initials: B
authors.lastname: Bakbak
authors.affiliation: Selçuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Beyoğlu
authors.affiliation: Selçuk University Faculty of Medicine, Department of Medical Genetics, Konya, Turkey.
authors.forename: Nadir
authors.initials: N
authors.lastname: Koçak
keywords: Papillophlebitis; hyperhomocycteinemia; methylenetetrahyrofolate reductase mutation