title: Chemical complexity of odors increases reliability of olfactory threshold testing.
abstract: Assessment of odor thresholds is a widely recognized method of measuring olfactory abilities in humans. To date no attempts have been made to assess whether chemical complexity of odors used can produce more reliable results. To this end, we performed two studies of repeated measures design with 121 healthy volunteers (age 19-62 years). In Study 1, we compared thresholds obtained from tests based on one odor presented in a pen-like odor dispensing device with three odors and six odors mixtures presented in glass containers. In study 2 we compared stimuli of one and three odors, both presented in glass containers. In both studies measurements were performed twice, separated by at least three days. Results indicate that the multiple odor mixtures produced more reliable threshold scores, as compared to thresholds based on a single substance.
authors.affiliation: Interdisciplinary Center, "Smell &Taste", Department of Otorhinolaryngology, TU Dresden, Germany.|Institute of Psychology, University of Wroclaw, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Oleszkiewicz
authors.affiliation: Interdisciplinary Center, "Smell &Taste", Department of Otorhinolaryngology, TU Dresden, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Pellegrino
authors.affiliation: Interdisciplinary Center, "Smell &Taste", Department of Otorhinolaryngology, TU Dresden, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Pusch
authors.affiliation: Interdisciplinary Center, "Smell &Taste", Department of Otorhinolaryngology, TU Dresden, Germany.
authors.forename: Celine
authors.initials: C
authors.lastname: Margot
authors.affiliation: Interdisciplinary Center, "Smell &Taste", Department of Otorhinolaryngology, TU Dresden, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Hummel
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D012684:Sensory Thresholds / Q000502:physiology*; D012903:Smell; D055815:Young Adult