title: Cryptosporidiosis outbreak at an academic animal research laboratory-Colorado, 2014.
abstract: BACKGROUND
  After cryptosporidiosis was reported in three workers caring for preweaned calves at an academic research laboratory, we sought to identify cases, determine risk factors, and implement control measures.
  
  
  METHODS
  A cryptosporidiosis case was defined as diarrhea duration ≥72 hr, abdominal cramps, or vomiting in an animal research laboratory worker during July 14-July 31. A confirmed case had laboratory evidence of Cryptosporidium infection. Staff were interviewed regarding illness, potential exposures, training, and personal protective equipment (PPE) standard operating procedures (SOPs).
  
  
  RESULTS
  The cryptosporidiosis attack rate (AR) was 74% (20/27); five were laboratory-confirmed. Median job training was 2 hr including respiratory-fit testing. No SOPs existed for doffing PPE. AR for workers who removed their gloves first was 84% (16/19) compared with 20% (1/5) for workers who removed gloves last (risk ratio = 4.2; P < 0.02).
  
  
  CONCLUSIONS
  This outbreak highlights the importance of adequate training, enforced proper PPE procedures, and promoting a culture of safety. Am. J. Ind. Med. 60:208-214, 2017. © 2017 Wiley Periodicals, Inc.
authors.affiliation: Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA.|Disease Control and Environmental Epidemiology Division, Colorado Department of Public Health and Environment, South Denver, CO.
authors.forename: Jessica
authors.initials: J
authors.lastname: Hancock-Allen
authors.affiliation: Disease Control and Environmental Epidemiology Division, Colorado Department of Public Health and Environment, South Denver, CO.
authors.forename: Nisha B
authors.initials: NB
authors.lastname: Alden
authors.affiliation: Disease Control and Environmental Epidemiology Division, Colorado Department of Public Health and Environment, South Denver, CO.
authors.forename: Alicia B
authors.initials: AB
authors.lastname: Cronquist
mesh_terms: D000328:Adult; D000818:Animals; D003120:Colorado; D003457:Cryptosporidiosis / Q000175:diagnosis*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007753:Laboratories; D059232:Laboratory Personnel; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis*; D016273:Occupational Exposure / Q000009:adverse effects*; D016272:Occupational Health; D012108:Research Personnel; D014495:Universities; D055815:Young Adult
keywords: cryptosporidiosis; disease outbreaks; occupational health; zoonoses