title: Prevalence of antepartum hemorrhage in women with placenta previa: a systematic review and meta-analysis.
abstract: Antepartum hemorrhage (APH) is an important cause of perinatal mortality and maternal morbidity in pregnant women with placenta previa in the world. However, the epidemiological characteristics are not completely understood. We performed an initial systematic review and meta-analysis to assess the prevalence of APH in pregnant women with placenta previa. It was totally performed following the Preferred Reporting Items for Systematic reviews and Meta-Analysis statement. PubMed, Elsevier Science Direct, and the Cochrane Library were searched before April 2016. A meta-analysis with a random-effects model based on a proportions approach was performed to determine the prevalence. Stratified analyses, meta-regression method, and sensitivity analysis were utilized to analyze the heterogeneity. A total of 29 articles were included. The pooled overall prevalence of APH among pregnant women with placenta previa was 51.6% (95% CI 42.7-60.6) in a heterogeneous set of studies (I2= 97.9). Correlation analysis found that there was a positive correlation between prevalence and percentage of multiparous (r = 0.534, P = 0.027) and a negative correlation between prevalence and survey year (r = -0.400, P = 0.031). In conclusion, the prevalence of APH was a high condition among pregnant women with placenta previa.
authors.affiliation: Department of Obsterics, South Medical University Affiliated Maternal &Child Health Hospital of Foshan, Foshan, Guangdong, 528000, China.|Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, 230032, China.
authors.forename: Dazhi
authors.initials: D
authors.lastname: Fan
authors.affiliation: School of Integrated Traditional and Western Medicine, Anhui University of Chinese Medicine, Hefei, Anhui, 230038, China.
authors.forename: Song
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, 230032, China.|Department of Library, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, 230032, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Xia
authors.affiliation: Department of Obsterics, South Medical University Affiliated Maternal &Child Health Hospital of Foshan, Foshan, Guangdong, 528000, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Obsterics, South Medical University Affiliated Maternal &Child Health Hospital of Foshan, Foshan, Guangdong, 528000, China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Guo
authors.affiliation: Department of Obsterics, South Medical University Affiliated Maternal &Child Health Hospital of Foshan, Foshan, Guangdong, 528000, China.
authors.forename: Zhengping
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010298:Parity; D010923:Placenta Previa / Q000473:pathology*; D011247:Pregnancy; D015995:Prevalence; D012044:Regression Analysis; D014592:Uterine Hemorrhage / Q000150:complications* / Q000453:epidemiology*