title: Effects of a New Eyelid Shampoo on Lid Hygiene and Eyelash Length in Patients with Meibomian Gland Dysfunction: A Comparative Open Study.
abstract: Purpose. Meibomian gland dysfunction (MGD) can lead to abnormalities in the composition and function of tear film, resulting in dry eye. Eyelid hygiene is a key to management of MGD. We tested a novel eyelid shampoo (Eye Shampoo Long, ESL) for its ability to maintain lid hygiene. This shampoo is nonirritating and can potentially lengthen eyelashes. This study was aimed to evaluate the efficacy of ESL in the treatment of MGD and its effects on eyelash length.Methods. Ten patients with MGD and 10 healthy subjects without MGD applied ESL twice daily for 8 weeks. Patients were examined for lid margin and dry eye before and after the trial. Subjective symptoms were evaluated. Eyelash length was measured at baseline and at the end of the trial.Results. In the MGD group, significant improvements were observed in subjective symptoms obstruction of the meibomian orifice, secretion of meibum, eyelashes contamination, eyelid margin foam, and SPK. Eyelash length became significantly longer.Conclusions. Maintaining eyelid hygiene using ESL improved the eyelid margins and symptoms of dry eye in MGD patients and increased eyelash length. These findings are promising and warrant confirmation in a larger randomized controlled study.
authors.affiliation: Minamiaoyama Eye Clinic, Renai Aoyama Building 4F, 3-3-11 Kitaaoyama, Minato-ku, Tokyo 107-0061, Japan.
authors.forename: Asuka
authors.identifier: 0000-0002-9244-5642
authors.initials: A
authors.lastname: Kobayashi
authors.affiliation: Minamiaoyama Eye Clinic, Renai Aoyama Building 4F, 3-3-11 Kitaaoyama, Minato-ku, Tokyo 107-0061, Japan; Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 1608582, Japan.
authors.forename: Takeshi
authors.identifier: 0000-0002-7712-0997
authors.initials: T
authors.lastname: Ide
authors.affiliation: Minamiaoyama Eye Clinic, Renai Aoyama Building 4F, 3-3-11 Kitaaoyama, Minato-ku, Tokyo 107-0061, Japan; Kikugawa Eye Clinic, 5134 Kamo Kikukawa-shi, Shizuoka, Japan.
authors.forename: Teruki
authors.identifier: 0000-0001-8734-3871
authors.initials: T
authors.lastname: Fukumoto
authors.affiliation: Minamiaoyama Eye Clinic, Renai Aoyama Building 4F, 3-3-11 Kitaaoyama, Minato-ku, Tokyo 107-0061, Japan; Miki Eye Clinic, 1-5 Iwata Tsu-shi, Mie, Japan.
authors.forename: Emiko
authors.initials: E
authors.lastname: Miki
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 1608582, Japan.
authors.forename: Kazuo
authors.identifier: 0000-0002-8874-7111
authors.initials: K
authors.lastname: Tsubota
authors.affiliation: Minamiaoyama Eye Clinic, Renai Aoyama Building 4F, 3-3-11 Kitaaoyama, Minato-ku, Tokyo 107-0061, Japan; Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 1608582, Japan.
authors.forename: Ikuko
authors.identifier: 0000-0001-6284-4290
authors.initials: I
authors.lastname: Toda