title: Holmium laser transurethral resection of bladder tumor: Our experience.
abstract: OBJECTIVE
  To compare the safety and efficiency of conventional monopolar and holmium laseren bloctransurethral resection of bladder tumor (CM-TURBT and HoL-EBRBT) while managing primary nonmuscle-invasive bladder cancer.
  
  
  METHODS
  From January 2012 to October 2015, fifty patients with primary nonmuscle-invasive bladder cancer underwent endoscopic surgery. Among them, 27 patients underwent CM-TURBT and 23 patients underwent HoL-EBRBT. Clinical data, included preoperative, operative, and postoperative management and follow-up, were recorded.
  
  
  RESULTS
  Patient demographics and tumor characteristics in both groups were compared before surgery. There was no significant difference in operative duration among the groups. Compared with the CM-TURBT group, HoL-EBRBT group had less intraoperative and postoperative complications, including obturator nerve reflex (P< 0.01), bladder perforation (P< 0.01), as well as bleeding and postoperative bladder irritation (P< 0.01). There were no significant differences among the two groups in the transfusion rate and occurrence of urethral strictures. Patients in the HoL-EBRBT group had less catheterization and hospitalization time than those in the CM-TURBT group (P< 0.01), and there were no significant differences in each risk subgroup as well as the overall recurrence rate among the CM-TURBT and HoL-EBRBT groups.
  
  
  CONCLUSIONS
  HoL-EBRBT might prove to be preferable alternatives to CM-TURBT management of nonmuscle-invasive bladder cancer. HoL-EBRBT however did not demonstrate an obvious advantage over CM-TURBT in tumor recurrence rate.
authors.affiliation: Department of Urology, Yenepoya Medical College and Hospital, Mangalore, Karnataka, India.
authors.forename: Nischith
authors.initials: N
authors.lastname: D'souza
authors.affiliation: Department of Urology, Yenepoya Medical College and Hospital, Mangalore, Karnataka, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Verma
keywords: Holmium laser en bloc tumor resection; laser transurethral resection of the bladder tumor; nonmuscle-invasive bladder tumor; trans-urethral resection of bladder tumor