title: Outbreak of Elizabethkingia meningoseptica sepsis with meningitis in a well-baby nursery.
abstract: Between March and May 2012, three neonates born at a regional maternity hospital developed Elizabethkingia meningoseptica (previously Chryseobacterium meningosepticum) sepsis with meningitis aged <10 days, and were treated successfully with intravenous ciprofloxacin plus vancomycin or piperacillin-tazobactam for three to six weeks. Four (16.6%) of 24 environmental specimens obtained from the nursery and delivery room were positive for this organism. All of the clinical isolates and two isolates from storage boxes for pacifiers and pacifier covers were genetically identical. After changing the storage boxes to stainless steel boxes that underwent regular autoclave sterilization, there were no further cases of infection with E. meningoseptica.
authors.affiliation: Department of Paediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: I-C
authors.initials: IC
authors.lastname: Tai
authors.affiliation: Department of Laboratory Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: T-P
authors.initials: TP
authors.lastname: Liu
authors.affiliation: Department of Paediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Y-J
authors.initials: YJ
authors.lastname: Chen
authors.affiliation: Department of Paediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: R-I
authors.initials: RI
authors.lastname: Lien
authors.affiliation: Tao-Yuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
authors.forename: C-Y
authors.initials: CY
authors.lastname: Lee
authors.affiliation: Department of Paediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan. Electronic address: ychuang@cgmh.org.tw.
authors.forename: Y-C
authors.initials: YC
authors.lastname: Huang
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002656:Child Day Care Centers; D045247:Chryseobacterium / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D004783:Environmental Microbiology; D005260:Female; D045826:Flavobacteriaceae Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D017053:Infection Control / Q000379:methods; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D017720:Molecular Epidemiology; D058889:Molecular Typing; D018805:Sepsis / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents
keywords: Elizabethkingia meningoseptica; Outbreak; Term neonates; Well-baby nursery