title: Feasibility Study on Applying Radiophotoluminescent Glass Dosimeters for CyberKnife SRS Dose Verification.
abstract: CyberKnife is one of multiple modalities for stereotactic radiosurgery (SRS). Due to the nature of CyberKnife and the characteristics of SRS, dose evaluation of the CyberKnife procedure is critical. A radiophotoluminescent glass dosimeter was used to verify the dose accuracy for the CyberKnife procedure and validate a viable dose verification system for CyberKnife treatment. A radiophotoluminescent glass dosimeter, thermoluminescent dosimeter, and Kodak EDR2 film were used to measure the lateral dose profile and percent depth dose of CyberKnife. A Monte Carlo simulation for dose verification was performed using BEAMnrc to verify the measured results. This study also used a radiophotoluminescent glass dosimeter coupled with an anthropomorphic phantom to evaluate the accuracy of the dose given by CyberKnife. Measurements from the radiophotoluminescent glass dosimeter were compared with the results of a thermoluminescent dosimeter and EDR2 film, and the differences found were less than 5%. The radiophotoluminescent glass dosimeter has some advantages in terms of dose measurements over CyberKnife, such as repeatability, stability, and small effective size. These advantages make radiophotoluminescent glass dosimeters a potential candidate dosimeter for the CyberKnife procedure. This study concludes that radiophotoluminescent glass dosimeters are a promising and reliable dosimeter for CyberKnife dose verification with clinically acceptable accuracy within 5%.
authors.affiliation: Medical Physics and Radiation Measurements Laboratory, Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC.|Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC.|Biophotonics and Molecular Imaging Research Center, National Yang-Ming University, Taipei, Taiwan, ROC.
authors.forename: Shih-Ming
authors.initials: SM
authors.lastname: Hsu
authors.affiliation: Division of Radiation Therapy and Oncology, Chang Gung Memorial Hospital, Chia-Yi, Taiwan, ROC.
authors.forename: Chao-Hsiung
authors.initials: CH
authors.lastname: Hung
authors.affiliation: School of Medical Laboratory Science and Biotechnology, Collage of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan, ROC.
authors.forename: Yi-Jen
authors.initials: YJ
authors.lastname: Liao
authors.affiliation: Department of radiation Oncology, MacKay Memorial Hospital, New-Taipei, Taiwan, ROC.
authors.forename: Hsiao-Mei
authors.initials: HM
authors.lastname: Fu
authors.affiliation: CyberKnife Treatment Center, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan, ROC.
authors.forename: Jo-Ting
authors.initials: JT
authors.lastname: Tsai
authors.affiliation: Department of Medical Imaging and Radiological Sciences, I-Shou University, Taiwan, R.O.C.
authors.forename: Yung-Hui
authors.initials: YH
authors.lastname: Huang
authors.affiliation: Medical Physics Graduate Program at Duke Kunshan University, Kunshan, Jiangsu, China.
authors.forename: David Y C
authors.initials: DY
authors.lastname: Huang
mesh_terms: D003198:Computer Simulation; D005240:Feasibility Studies; D005898:Glass / Q000737:chemistry*; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D000072232:Radiation Dosimeters; D016634:Radiosurgery / Q000295:instrumentation*; D011879:Radiotherapy Dosage; D015203:Reproducibility of Results; D013819:Thermoluminescent Dosimetry / Q000295:instrumentation*