title: Total resection combined with osteotomy is more effective for orbital solitary fibrous tumor excision: a report of three cases.
abstract: A solitary fibrous tumor is a neoplasm generally arising from the mesothelial surfaces of the pleura and mesothelium. In this paper, we describe three cases of rare solitary fibrous tumors arising from the orbit and discuss the management of the tumors, including diagnosis and treatment. All three cases were treated by surgical resection and showed satisfactory aesthetic and functional results. For a definitive diagnosis, immunohistochemical staining for proteins such as vimentin, CD34 and bcl-2 and hematoxylin and eosin (H&E) staining for identifying the morphological characteristics of spindle cell tumors with a partially storiform pattern and staghorn vessels are indispensable. The principle of treatment for orbital solitary fibrous tumor is complete resection because the prognosis depends on controlling tumor progression, which can be difficult with chemotherapy and radiotherapy alone.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, Japan. tnkktya@gmail.com.
authors.forename: Katsuya
authors.identifier: http://orcid.org/0000-0001-9566-902X
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: Department of Plastic and Reconstructive Surgery, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yano
authors.affiliation: Investigative Pathology, Nagasaki University School of Medicine, Nagasaki, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Hayashi
authors.affiliation: Department of Plastic and Reconstructive Surgery, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, Japan.
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Hirano
mesh_terms: D000328:Adult; D000368:Aged; D018952:Antigens, CD34 / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery*; D010027:Osteotomy / Q000379:methods*; D054364:Solitary Fibrous Tumors / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D014746:Vimentin / Q000378:metabolism
chemical_list: D018952:Antigens, CD34; D014408:Biomarkers, Tumor; D014746:Vimentin
keywords: Immunohistochemistry; Orbital tumor; Pathology; Solitary fibrous tumor; Surgical treatment