title: Choroidal thickness findings in two siblings with nanophthalmos by swept source-OCT: a case report.
abstract: BACKGROUND
  We investigated choroidal thicknesses at five sites in two siblings (four eyes) with nanophthalmos using swept-source optical coherence tomography.
  
  
  METHODS
  Case 1, a 51-year-old Japanese female with high hyperopia (Right: +20.5 Dioptors, Left: +19.5 Dioptors), had axial lengths of 15.6 mm in both eyes. Case 2, a 55-year-old Japanese male with high hyperopia (Right: +22.5 Dioptors, Left: +22.8 Dioptors), had axial lengths of 14.8 and 14.7 mm in the right and left eyes, respectively. Choroidal thickness was measured at five sites in each eye using swept-source optical coherence tomography; subfoveal, nasal, temporal, superior and inferior (the 4 non-subfoveal sites were measured 3000 µm from the fovea).
  
  
  CONCLUSIONS
  The mean choroidal thickness was 355.8 ± 63.6 μm at the subfoveal, 466.3 ± 85.1 μm at the nasal, 274.8 ± 77.2 μm at the temporal, 396.8 ± 54.6 μm at the superior, and 480.8 ± 66.8 μm at the inferior (mean ± standard deviation) site. Choroidal thickness was maximal at the inferior site. The choroid was thinnest, in diminishing order, at the nasal, superior, subfoveal and temporal sites.
authors.affiliation: Division of Ophthalmology, Department of Visual Science, Nihon University School of Medicine, Nihon University Hospital, 1-6 Surugadai, Kanda, Chiyoda-ku, Tokyo, 101-8309, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kaneko
authors.affiliation: Division of Ophthalmology, Department of Visual Science, Nihon University School of Medicine, Nihon University Hospital, 1-6 Surugadai, Kanda, Chiyoda-ku, Tokyo, 101-8309, Japan. ariearly7@gmail.com.
authors.forename: Ari
authors.initials: A
authors.lastname: Shinojima
authors.affiliation: Division of Ophthalmology, Department of Visual Science, Nihon University School of Medicine, Nihon University Hospital, 1-6 Surugadai, Kanda, Chiyoda-ku, Tokyo, 101-8309, Japan.
authors.forename: Mori
authors.initials: M
authors.lastname: Ryusaburo
authors.affiliation: Division of Ophthalmology, Department of Visual Science, Nihon University School of Medicine, Nihon University Hospital, 1-6 Surugadai, Kanda, Chiyoda-ku, Tokyo, 101-8309, Japan.
authors.forename: Akiyuki
authors.initials: A
authors.lastname: Kawamura
authors.affiliation: Division of Ophthalmology, Department of Visual Science, Nihon University School of Medicine, Nihon University Hospital, 1-6 Surugadai, Kanda, Chiyoda-ku, Tokyo, 101-8309, Japan.
authors.forename: Mitsuko
authors.initials: M
authors.lastname: Yuzawa
mesh_terms: D002829:Choroid / Q000473:pathology*; D015785:Eye Diseases, Hereditary / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012590:Sclera / Q000473:pathology; D035781:Siblings; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
keywords: Axial length; Choroidal thickness; Hyperopia; Nanophthalmos; Optical coherence tomography