title: A clinical and safety review of paracetamol and ibuprofen in children.
abstract: The antipyretic analgesics, paracetamol, and non-steroidal anti-inflammatory agents NSAIDs are one of the most widely used classes of medications in children. The aim of this review is to determine if there are any clinically relevant differences in safety between ibuprofen and paracetamol that may recommend one agent over the other in the management of fever and discomfort in children older than 3 months of age.
authors.affiliation: Evelina Children's Hospital, London, SE1 7EH, UK. dkanabar@doctors.org.uk.
authors.forename: Dipak J
authors.identifier: http://orcid.org/0000-0001-6561-6533
authors.initials: DJ
authors.lastname: Kanabar
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects*; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002648:Child; D062787:Drug Overdose / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D004632:Emergency Medical Services / Q000639:trends; D005334:Fever / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*
chemical_list: D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen; D007052:Ibuprofen
keywords: Acetaminophen; Children; Ibuprofen; Paracetamol; Safety