title: Cardiovascular Consequences of Binge Drinking: An Integrative Review with Implications for Advocacy, Policy, and Research.
abstract: Worldwide, binge drinking is a major public health problem. The popularized health risks associated with binge drinking include physical injury and motor vehicle crashes; less attention has been given to the negative effects on the cardiovascular (CV) system. The primary aims of this review were to provide a summary of the adverse effects of binge drinking on the risk and development of CV disease and to review potential pathophysiologic mechanisms. Using specific inclusion criteria, an integrative review was conducted that included data from human experimental, prospective cross-sectional, and cohort epidemiological studies that examined the association between binge drinking and CV conditions such as hypertension (HTN), myocardial infarction (MI), stroke, and arrhythmias. Studies were identified that examined the relationship between binge drinking and CV outcomes. Collectively, findings support that binge drinking is associated with a higher risk of pre-HTN, HTN, MI, and stroke in middle-aged and older adults. Binge drinking may also have adverse CV effects in young adults (aged 18 to 30). Mechanisms remain incompletely understood; however, available evidence suggests that binge drinking may induce oxidative stress and vascular injury and be proatherogenic. Public health messages regarding binge drinking need to include the effects of binge drinking on the CV system.
authors.affiliation: Department of Biobehavioral Health Science, University of Illinois at Chicago, Chicago, Illinois.
authors.forename: Mariann R
authors.initials: MR
authors.lastname: Piano
authors.affiliation: Department of Physical Therapy, University of Illinois at Chicago, Chicago, Illinois.|Department of Physical Therapy, Federal University of São Carlos, São Paulo, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Mazzuco
authors.affiliation: Department of Biobehavioral Health Science, University of Illinois at Chicago, Chicago, Illinois.
authors.forename: Minkyung
authors.initials: M
authors.lastname: Kang
authors.affiliation: Department of Physical Therapy, University of Illinois at Chicago, Chicago, Illinois.
authors.forename: Shane A
authors.initials: SA
authors.lastname: Phillips
mesh_terms: D063425:Binge Drinking / Q000453:epidemiology / Q000503:physiopathology* / Q000517:prevention & control; D035843:Biomedical Research / Q000331:legislation & jurisprudence / Q000379:methods*; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000503:physiopathology* / Q000517:prevention & control; D015331:Cohort Studies; D003254:Consumer Advocacy / Q000331:legislation & jurisprudence; D003430:Cross-Sectional Studies; D006291:Health Policy / Q000331:legislation & jurisprudence; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000503:physiopathology; D011446:Prospective Studies
keywords: Alcohol; Binge Drinking; Cardiovascular Conditions; Myocardial Infarction; Stroke