title: Transition Metal-Catalyzed C-H Amination: Scope, Mechanism, and Applications.
abstract: Catalytic transformation of ubiquitous C-H bonds into valuable C-N bonds offers an efficient synthetic approach to construct N-functionalized molecules. Over the last few decades, transition metal catalysis has been repeatedly proven to be a powerful tool for the direct conversion of cheap hydrocarbons to synthetically versatile amino-containing compounds. This Review comprehensively highlights recent advances in intra- and intermolecular C-H amination reactions utilizing late transition metal-based catalysts. Initial discovery, mechanistic study, and additional applications were categorized on the basis of the mechanistic scaffolds and types of reactions. Reactivity and selectivity of novel systems are discussed in three sections, with each being defined by a proposed working mode.
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST) , Daejeon 34141, Republic of Korea.|Center for Catalytic Hydrocarbon Functionalizations, Institute of Basic Science (IBS) , Daejeon 34141, Republic of Korea.
authors.forename: Yoonsu
authors.initials: Y
authors.lastname: Park
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST) , Daejeon 34141, Republic of Korea.|Center for Catalytic Hydrocarbon Functionalizations, Institute of Basic Science (IBS) , Daejeon 34141, Republic of Korea.
authors.forename: Youyoung
authors.initials: Y
authors.lastname: Kim
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST) , Daejeon 34141, Republic of Korea.|Center for Catalytic Hydrocarbon Functionalizations, Institute of Basic Science (IBS) , Daejeon 34141, Republic of Korea.
authors.forename: Sukbok
authors.identifier: http://orcid.org/0000-0001-9069-0946
authors.initials: S
authors.lastname: Chang