title: The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil.
abstract: BACKGROUND
  Breast cancer is the most common cause of cancer death among women.
  
  
  OBJECTIVE
  The objective of this study was to analyze time trends in overall mortality from breast cancer in Brazil, Brazilian regions and States.
  
  
  METHODS
  This is an exploratory study, of the time series of deaths from breast cancer contained in the Mortality Information System (SIM), of women living in Brazil, Brazilian regions and States, from 1996 to 2013. For the trend analysis, the polynomial regression model was used, and a significant trend was considered when the estimated model obtained a p value <0.05.
  
  
  RESULTS
  There was a tendency of increased mortality from breast cancer in Brazilian women (average increase of 0.18 per year; p <0.001), with regional differences, particularly in the age group 20-49 years (0.07 per year; p <0.001). The age group 50-69 years remained constant but had high average rates (37.14).
  
  
  CONCLUSIONS
  More effective planning is needed to focus on the different scenarios of the Brazilian regions. Screening strategies for the incidence and mortality from breast cancer must also be rethought according to age group in the country.
authors.affiliation: Health Science Center, State University of Maringa, Maringa, Parana, Brazil.
authors.forename: Sheila Cristina
authors.identifier: http://orcid.org/0000-0002-0591-7307
authors.initials: SC
authors.lastname: Rocha-Brischiliari
authors.affiliation: Department of Nursing, State University of Maringa, Maringa, Parana, Brazil.
authors.forename: Rosana Rosseto de
authors.initials: RR
authors.lastname: Oliveira
authors.affiliation: Department of Medicine, State University of Maringa, Maringa, Parana, Brazil.
authors.forename: Luciano
authors.initials: L
authors.lastname: Andrade
authors.affiliation: Department of Nursing, State University of Maringa, Maringa, Parana, Brazil.
authors.forename: Adriano
authors.initials: A
authors.lastname: Brischiliari
authors.affiliation: Health Science Center, State University of Maringa, Maringa, Parana, Brazil.
authors.forename: Angela Andreia França
authors.initials: AA
authors.lastname: Gravena
authors.affiliation: Department of Post Graduate in Health Science, State University of Maringa, Maringa, Parana, Brazil.
authors.forename: Maria Dalva de Barros
authors.initials: MD
authors.lastname: Carvalho
authors.affiliation: Department of Post Graduate in Health Science and Nursing, State University of Maringa, Maringa, Parana, Brazil.
authors.forename: Sandra Marisa
authors.initials: SM
authors.lastname: Pelloso
mesh_terms: D000328:Adult; D000368:Aged; D001938:Brazil; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000401:mortality*; D003625:Data Collection; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D015233:Models, Statistical; D009026:Mortality / Q000639:trends; D012044:Regression Analysis; D055815:Young Adult