title: Absorption and metabolization of sex hormones and their transformation into contraceptive technologies: the paths taken by medical thought in Brazil.
abstract: The article analyses knowledge assimilation and the development of clinical and research practices relating to sex hormones among Brazilian gynaecologists. It discusses the paths taken by medical thought from the reception of the hormones to their transformation into contraceptives. Our objective is to comprehend styles of introducing and disseminating medical technologies in the area of reproductive health in Brazil. It uses methods of historical analysis and takes as its source the Anais Brasileiros de Ginecologia, a journal published between 1936 and 1970. From the outset, the accompaniment of scientific breakthroughs in relation to sex hormones and their use to treat diverse female illnesses played a key role in the rapid medical acceptance of hormonal contraception. Scientific and technical questions (side effects, dosages) and the demographic issue formed part of the majority of the debates. Objections from the Catholic Church were considered but did not set the agenda of medical thought on contraceptives. The quest to consolidate gynaecology as a scientific, modern and cosmopolitan area of expertise, along with sanitary and demographic motives that allowed contraceptives to be classed as ethical drugs, are identified as processes underlying the assimilation and metabolization of sex hormones as hormonal contraceptives.
authors.affiliation: Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fiocruz. Av. Rui Barbosa 716, Flamengo. 22250-020 Rio de Janeiro RJ Brasil. cbonan@globo.com.
authors.forename: Claudia
authors.initials: C
authors.lastname: Bonan
authors.affiliation: Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fiocruz. Av. Rui Barbosa 716, Flamengo. 22250-020 Rio de Janeiro RJ Brasil. cbonan@globo.com.
authors.forename: Luiz Antonio
authors.initials: LA
authors.lastname: Teixeira
authors.affiliation: Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fiocruz. Av. Rui Barbosa 716, Flamengo. 22250-020 Rio de Janeiro RJ Brasil. cbonan@globo.com.
authors.forename: Andreza Rodrigues
authors.initials: AR
authors.lastname: Nakano
mesh_terms: D035843:Biomedical Research / Q000379:methods*; D020811:Biomedical Technology / Q000379:methods; D001938:Brazil; D003271:Contraceptive Agents, Female / Q000008:administration & dosage*; D004059:Diffusion of Innovation; D015195:Drug Design; D005260:Female; D012739:Gonadal Steroid Hormones / Q000008:administration & dosage*; D006176:Gynecology; D006801:Humans
chemical_list: D003271:Contraceptive Agents, Female; D012739:Gonadal Steroid Hormones