title: Angioimmunoblastic T-cell Lymphoma Associated with IgA Nephropathy.
abstract: Few cases of IgA nephropathy with angioimmunoblastic T-cell lymphoma (AITL) have been reported. We herein present the case of a 79-year-old Japanese man with AITL and IgA nephropathy. The patient presented with generalized edema, fatigue, and fever. Laboratory investigations revealed polyclonal gammopathy with a high level of IgA, microscopic hematuria, proteinuria, and some other immunological abnormalities. Computed tomography revealed generalized lymphadenopathy. A diagnosis of AITL and IgA nephropathy was made based on inguinal lymph node and renal biopsies. Following chemotherapy for AITL, the patient's edema, microscopic hematuria, and proteinuria were alleviated. These findings indicate that IgA nephropathy may occur in AITL patients.
authors.affiliation: Department of Internal Medicine, Nagano Chuo Hospital, Japan.
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Harada
authors.forename: Kei
authors.initials: K
authors.lastname: Sakai
authors.forename: Shiho
authors.initials: S
authors.lastname: Asaka
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Nakayama
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D044466:Asian People; D005922:Glomerulonephritis, IGA / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D007564:Japan; D008198:Lymph Nodes / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000150:complications*; D008297:Male
chemical_list: D000970:Antineoplastic Agents