title: Effect of medical treatment on histological findings in rabbits with acute appendicitis.
abstract: BACKGROUND
  Acute appendicitis (AA) is the most common reason for abdominal surgery in the world. The aim of this study was to evaluate the effect of medical treatment on histological findings in rabbits with AA.
  
  
  METHODS
  Twenty-one male New Zealand rabbits were divided into 3 groups: appendix ligation and medical treatment, appendix ligation and no treatment, and control group, which underwent only laparotomy.
  
  
  RESULTS
  In appendix ligation without treatment group, AA findings were much more severe.
  
  
  CONCLUSIONS
  Medical treatment reduced inflammation of AA.
authors.forename: Gürcan
authors.initials: G
authors.lastname: Şimşek
authors.affiliation: Department of General Surgery, Sarıkaya State Hospital, Yozgat-Turkey. drbarissevinc@gmail.com.
authors.forename: Barış
authors.initials: B
authors.lastname: Sevinç
authors.forename: Yaşar
authors.initials: Y
authors.lastname: Ünlü
authors.forename: İsmail
authors.initials: İ
authors.lastname: Hasırcı
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Kurku
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Karahan
mesh_terms: D000208:Acute Disease; D000818:Animals; D001064:Appendicitis / Q000473:pathology / Q000601:surgery*; D001065:Appendix / Q000098:blood supply*; D004195:Disease Models, Animal; D007511:Ischemia / Q000473:pathology*; D007813:Laparotomy; D008297:Male; D011817:Rabbits