title: Regio-selective synthesis of diversely substituted benzo[a]carbazoles through Rh(iii)-catalyzed annulation of 2-arylindoles with α-diazo carbonyl compounds.
abstract: A novel synthetic approach toward benzo[a]carbazoles or 6-amino benzo[a]carbazoles containing an unprotected NH unit through Rh(iii)-catalyzed cascade reactions of 2-arylindoles or 2-arylindole-3-carbonitriles with α-diazo carbonyl compounds has been established. To our knowledge, this is the first example in which the NH unit of indole is used as a directing group for an intramolecular C(sp2)-H bond functionalization to give benzo[a]carbazole derivatives. Notably, this method features easily obtainable substrates, good functional group tolerance, excellent regio-selectivity, and high atom-efficiency.
authors.affiliation: School of Chemistry and Chemical Engineering, School of Environment, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University, Xinxiang, Henan 453007, China. xuesen.fan@htu.cn xinyingzhang@htu.cn.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering, School of Environment, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University, Xinxiang, Henan 453007, China. xuesen.fan@htu.cn xinyingzhang@htu.cn.
authors.forename: Beibei
authors.initials: B
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, School of Environment, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University, Xinxiang, Henan 453007, China. xuesen.fan@htu.cn xinyingzhang@htu.cn.
authors.forename: Xinying
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, School of Environment, Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University, Xinxiang, Henan 453007, China. xuesen.fan@htu.cn xinyingzhang@htu.cn.
authors.forename: Xuesen
authors.identifier: http://orcid.org/0000-0002-2040-6919
authors.initials: X
authors.lastname: Fan