title: The Results of Ultrasonography-Guided Percutaneous Radiofrequency Ablation in Hyperparathyroid Patients in Whom Surgery Is Not Feasible.
abstract: BACKGROUND
  The aim of the study was to evaluate the results of ultrasonography (US)-guided percutaneous radiofrequency ablation (RFA) in hyperparathyroid patients who refused surgery or had high surgical risks.
  
  
  METHODS
  Five patients with hyperparathyroidism (HPT) underwent US-guided RFA for a single hyperfunctioning parathyroid lesion. Post-ablation serum calcium and parathormone (PTH) assays were performed. All patients underwent imaging studies 6 months after the ablation to visualize the post-ablation change in the size of the treated parathyroid lesions.
  
  
  RESULTS
  All patients were normocalcemic on the post-ablation 1st day and 6th month. The post-ablation PTH levels were normal in three patients but remained elevated in two patients. The size of the parathyroid lesion was ≥30 mm in the two patients with elevated PTH, whereas the lesion was smaller than 30 mm in those with normal post-ablation PTH values.
  
  
  CONCLUSIONS
  Although this is a limited case series, it demonstrates the potential feasibility of RFA for HPT. Benefits were achieved particularly in patients with small parathyroid lesions.
authors.affiliation: Istanbul Faculty of Medicine, Department of General Surgery, Istanbul University, Millet Caddesi Capa, Fatih, 34093, Istanbul, Turkey. icsormaz@gmail.com.
authors.forename: Ismail Cem
authors.initials: IC
authors.lastname: Sormaz
authors.affiliation: Istanbul Faculty of Medicine, Department of Radiology, Istanbul University, Istanbul, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Poyanlı
authors.affiliation: Istanbul Faculty of Medicine, Department of General Surgery, Istanbul University, Millet Caddesi Capa, Fatih, 34093, Istanbul, Turkey.
authors.forename: Sami
authors.initials: S
authors.lastname: Açar
authors.affiliation: Department of General Surgery, Fatih Sultan Mehmet Research and Education Hospital, Istanbul, Turkey.
authors.forename: Ahmet Yalın
authors.initials: AY
authors.lastname: İşcan
authors.affiliation: Istanbul Faculty of Medicine, Department of General Surgery, Istanbul University, Millet Caddesi Capa, Fatih, 34093, Istanbul, Turkey.
authors.forename: İlker
authors.initials: İ
authors.lastname: Ozgur
authors.affiliation: Istanbul Faculty of Medicine, Department of General Surgery, Istanbul University, Millet Caddesi Capa, Fatih, 34093, Istanbul, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Tunca
authors.affiliation: Istanbul Faculty of Medicine, Department of General Surgery, Istanbul University, Millet Caddesi Capa, Fatih, 34093, Istanbul, Turkey.
authors.forename: Yasemin Giles
authors.initials: YG
authors.lastname: Senyürek
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods*
keywords: Ablation; Hyperparathyroidism; Parathyroidectomy; Radiofrequency; Ultrasonography