title: Associations between perceived neighbourhood problems and quality of life in older adults with and without osteoarthritis: Results from the Hertfordshire Cohort Study.
abstract: This study examined whether the association of quality of life (QoL) with perceived neighbourhood problems is stronger in older adults with osteoarthritis (OA) than in those without OA. Of all 294 participants, 23.8% had OA. More perceived neighbourhood problems were associated with a stronger decrease in QoL over time in participants with OA (B=-0.018; p=0.02) than in those without OA (B=-0.004; p=0.39). Physical activity did not mediate this relationship. Older adults with OA may be less able to deal with more challenging environments.
authors.affiliation: Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands. Electronic address: ej.timmermans@vumc.nl.
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Timmermans
authors.affiliation: Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands.
authors.forename: Suzan
authors.initials: S
authors.lastname: van der Pas
authors.affiliation: Department of Health Sciences, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, The Netherlands.
authors.forename: Laura A
authors.initials: LA
authors.lastname: Schaap
authors.affiliation: MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, United Kingdom; NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
authors.forename: Cyrus
authors.initials: C
authors.lastname: Cooper
authors.affiliation: MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, United Kingdom.
authors.forename: Mark H
authors.initials: MH
authors.lastname: Edwards
authors.affiliation: MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, United Kingdom; Centre for Cognitive Ageing & Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.
authors.forename: Catharine R
authors.initials: CR
authors.lastname: Gale
authors.affiliation: Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands.
authors.forename: Dorly J H
authors.initials: DJ
authors.lastname: Deeg
authors.affiliation: MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, United Kingdom; School of Biological Sciences, Victoria University of Wellington, New Zealand.
authors.forename: Elaine M
authors.initials: EM
authors.lastname: Dennison
mesh_terms: D000368:Aged; D015331:Cohort Studies; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D010003:Osteoarthritis / Q000523:psychology*; D010465:Perception; D011788:Quality of Life / Q000523:psychology*; D012111:Residence Characteristics; D011795:Surveys and Questionnaires; D006113:United Kingdom
keywords: Neighbourhood problems; Older population; Osteoarthritis; Physical activity; Quality of life