title: Exosomal Small Talk Carries Strong Messages from Muscle Stem Cells.
abstract: Exosome-dependent intercellular communication is an emerging signaling mechanism involved in tissue repair and regeneration. Now in this issue of Cell Stem Cell, Fry et al. (2016) show that muscle stem cells communicate with fibrogenic cells by exosomal trafficking of microRNA-206 to regulate extracellular matrix deposition and muscle tissue remodeling.
authors.affiliation: Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Janelle M
authors.initials: JM
authors.lastname: Spinazzola
authors.affiliation: Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA; The Stem Cell Program at Boston Children's Hospital, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: gussoni@enders.tch.harvard.edu.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Gussoni
mesh_terms: D002450:Cell Communication; D055354:Exosomes; D006801:Humans; D032446:Myoblasts; D012038:Regeneration; D013234:Stem Cells