title: Influence of Age on Factors associated with Peri-implant Bone Loss after Prosthetic Rehabilitation over Osseointegrated Implants.
abstract: To verify the influence of age on factors associated with peri-implant bone loss after prosthetic rehabilitation over osseointegrated implants.
  
  
  
  This is an analytical, observational, and longitudinal study with initial 23 participants. Patients presenting with osseointegrated implants with their respective prostheses installed were included, and they could be carriers of chronic and degenerative diseases, such as diabetes, osteoporosis, hypothyroidism, cardiovascular disease (CVD), and systemic arterial hypertension. Thus, 18 participants with 57 implants were selected and followed up from 2009 to 2013. For statistical analysis, chi-square or Fisher's exact test was used for the association of systemic conditions and bone loss. Student's t-test was used for mean comparisons of age and number of total upper and lower implants.
  
  
  
  The average age of the sample studied was 71.05 years (65-80). The average implant per person was 3.2. Smoking had an influence on both mesial and distal bone loss, and the latter was significant (p = 0.0370). The association between bone loss and gender was also significant (p < 0.05). Moreover, male gender and upper implants were factors significantly associated with bone loss. The systemic conditions, when isolated, did not have significant influence on implant survival.
  
  
  
  Age is not a factor that, alone, contraindicates implant-rehabilitating therapy. On the contrary, smoking has a significant influence on dental implant survival. Systemic diseases, such as osteoporosis, hypothyroidism, diabetes, hypertension, and heart diseases, when controlled, are not contraindication factors.
  
  
  
  This study is relevant for assessing peri-implant bone loss in elderly patients, right after implant installation and over time. Therefore, it was possible to verify that age is not a limiting factor for this procedure. Controlled systemic diseases do not contraindicate implant installation, but smoking is a factor that affects implant survival.
authors.affiliation: Department of Gerodontology, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Rio Grande dos Sul, Brazil.
authors.forename: Rejane El
authors.initials: RE
authors.lastname: Pedro
authors.affiliation: Department of Dentistry, Passo Fundo University, Passo Fundo, Rio Grande do Sul, Brazil.
authors.forename: João P
authors.initials: JP
authors.lastname: De Carli
authors.affiliation: Department of Dentistry, Passo Fundo University, Passo Fundo, Rio Grande do Sul, Brazil.
authors.forename: Maria Ss
authors.initials: MS
authors.lastname: Linden
authors.affiliation: Department of Dentistry, Federal University of Sergipe Lagarto, Sergipe, Brazil.
authors.forename: Igor Fp
authors.initials: IF
authors.lastname: Lima
authors.affiliation: Department of Dentistry, Federal University of Sergipe Lagarto, Sergipe, Brazil, Phone: +5579991161896, e-mail: paranhos@ortodontista.com.br.
authors.forename: Luiz R
authors.initials: LR
authors.lastname: Paranhos
authors.affiliation: Department of Dentistry, University Tiradentes, Aracaju Sergipe, Brazil.
authors.forename: Max D
authors.initials: MD
authors.lastname: Costa
authors.affiliation: Department of Gerodontology, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Rio Grande dos Sul, Brazil.
authors.forename: Ângelo Jg
authors.initials: ÂJ
authors.lastname: Bós
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D016301:Alveolar Bone Loss / Q000453:epidemiology* / Q000209:etiology*; D000077280:Bone-Anchored Prosthesis; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002908:Chronic Disease; D019232:Dental Restoration Failure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008437:Maxilla; D011475:Prosthesis Failure; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects*
keywords: Aging; Case-control study; Chronic disease; Dental implants; Implants; Prostheses Risk factors.