title: Comparing Parafoveal Cone Photoreceptor Mosaic Metrics in Younger and Older Age Groups Using an Adaptive Optics Retinal Camera.
abstract: To analyze cone mosaic metrics on adaptive optics (AO) images as a function of retinal eccentricity in two different age groups using a commercial flood illumination AO device.
  
  
  
  Fifty-three eyes of 28 healthy subjects divided into two age groups were imaged using an AO flood-illumination camera (rtx1; Imagine Eyes, Orsay, France). A 16° × 4° field was obtained horizontally. Cone-packing metrics were determined in five neighboring 50 µm × 50 µm regions. Both retinal (cones/mm2and µm) and visual (cones/degrees2and arcmin) units were computed.
  
  
  
  Results for cone mosaic metrics at 2°, 2.5°, 3°, 4°, and 5° eccentricity were compatible with previous AO scanning laser ophthalmoscopy and histology data. No significant difference was observed between the two age groups.
  
  
  
  The rtx1 camera enabled reproducible measurements of cone-packing metrics across the extrafoveal retina. These findings may contribute to the development of normative data and act as a reference for future research. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:45-50.].
authors.forename: Julie
authors.initials: J
authors.lastname: Jacob
authors.forename: Michel
authors.initials: M
authors.lastname: Paques
authors.forename: Valérie
authors.initials: V
authors.lastname: Krivosic
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Dupas
authors.forename: Ali
authors.initials: A
authors.lastname: Erginay
authors.forename: Ramin
authors.initials: R
authors.lastname: Tadayoni
authors.forename: Alain
authors.initials: A
authors.lastname: Gaudric
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005584:Fovea Centralis / Q000166:cytology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D055095:Optics and Photonics; D010781:Photography / Q000295:instrumentation*; D012016:Reference Values; D015203:Reproducibility of Results; D017949:Retinal Cone Photoreceptor Cells / Q000166:cytology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D055815:Young Adult