title: The impact of male age on embryo quality: a retrospective study using time-lapse imaging.
abstract: OBJECTIVE
  This study aimed to correlate male age with embryo morphokinetic parameters on D3 considering the timing and the exact moment of embryo cleavage.
  
  
  METHODS
  Time-lapse imaging was used to produce an ideal cleavage curve for the embryos analyzed. The percentage of embryos under the curve was analyzed and correlated with male age.
  
  
  RESULTS
  32.6% of the embryos from patients aged 28-33 years were under the curve; 36.2% of the embryos from patients aged 34-39 years were under the curve; 41.3% of the embryos from patients aged 40-45 years were under the curve; and 26.3% of the embryos fro patients aged 46-57 years were under the curve.
  
  
  CONCLUSIONS
  a statistically non-significant decrease was observed in the percentage of embryos under the optimal cleavage curve on D3 in the group of men aged between 40 and 45 years. Further studies looking into embryos in the blastocyst stage (D5 or D6) are required.
authors.affiliation: Embryolife Reproductive Medicine Institute, São José dos Campos/SP.
authors.forename: Guilherme R F
authors.initials: GR
authors.lastname: Rosário
authors.affiliation: Embryolife Reproductive Medicine Institute, São José dos Campos/SP.
authors.forename: Diana S
authors.initials: DS
authors.lastname: Vidal
authors.affiliation: Embryolife Reproductive Medicine Institute, São José dos Campos/SP.
authors.forename: Adriana V
authors.initials: AV
authors.lastname: Silva
authors.affiliation: Embryolife Reproductive Medicine Institute, São José dos Campos/SP.
authors.forename: Antônio C C
authors.initials: AC
authors.lastname: Franco
keywords: Male age; embryo quality; morphokinetics; time-lapse