title: N-Heterocyclic carbene-palladium(ii)-1-methylimidazole complex catalyzed direct C-H bond arylation of imidazo[1,2-a]pyridines with aryl chlorides.
abstract: We herein reported the N-heterocyclic carbene-palladium(ii)-1-methylimidazole complex catalyzed direct C-H bond arylation of imidazo[1,2-a]pyridines with aryl chlorides. Under suitable conditions, all reactions between various imidazo[1,2-a]pyridines and aryl chlorides worked well to give the desired C3-H arylated products in acceptable to high yields, giving a convenient and alternative method for the direct C-H bond arylation of imidazo[1,2-a]pyridines, using economic and easily available aryl chlorides as the arylating reagents.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China. Shaolix@wzu.edu.cn.
authors.forename: Qing-Xian
authors.initials: QX
authors.lastname: Liu
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China. Shaolix@wzu.edu.cn.
authors.forename: Bang-Yue
authors.initials: BY
authors.lastname: He
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China. Shaolix@wzu.edu.cn.
authors.forename: Peng-Cheng
authors.initials: PC
authors.lastname: Qian
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China. Shaolix@wzu.edu.cn.
authors.forename: Li-Xiong
authors.identifier: http://orcid.org/0000-0002-7589-1800
authors.initials: LX
authors.lastname: Shao