title: Dental care in patients with antiphospholipid syndrome: two case reports.
abstract: Antiphospholipid syndrome (APS) is a prothrombotic autoimmune disease that may be classified as primary or secondary. Treatment consists of oral anticoagulant, antiplatelet, and/or immunosuppressant drugs. This report describes the dental treatment of 2 women with APS and multiple dental concerns, including periodontal disease, caries, and missing teeth. The invasive dental procedures were performed in an outpatient setting with hematologic monitoring and use of local hemostatic measures. Neither interruption of anticoagulant medications nor administration of blood products was necessary. All of the procedures were performed without complications. To date, no recommendations for the dental care of patients with APS have been established, demonstrating a need to investigate the risks for bleeding and infection, among other concerns, during dental treatment of these patients.
authors.forename: Karine Cestaro
authors.initials: KC
authors.lastname: Mesquita
authors.forename: Carolina Rodrigues
authors.initials: CR
authors.lastname: Teófilo
authors.forename: João Paulo Veloso
authors.initials: JP
authors.lastname: Perdigão
authors.forename: Fabrício Bitu
authors.initials: FB
authors.lastname: Sousa
authors.forename: Ana Paula Negreiros Nunes
authors.initials: AP
authors.lastname: Alves
authors.forename: Wagner Araújo
authors.initials: WA
authors.lastname: de Negreiros
authors.forename: Mário Rogério Lima
authors.initials: MR
authors.lastname: Mota
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D003729:Dental Care / Q000379:methods*; D003731:Dental Caries / Q000150:complications / Q000601:surgery; D003793:Dental Restoration, Permanent; D012534:Dental Scaling; D003832:Denture, Partial, Removable; D003970:Diastema / Q000601:surgery; D005260:Female; D005889:Gingival Recession / Q000150:complications; D006801:Humans; D007180:Incisor / Q000002:abnormalities / Q000601:surgery; D010510:Periodontal Diseases / Q000150:complications / Q000601:surgery; D016745:Root Planing; D014081:Tooth Extraction
keywords: anticoagulation therapy; antiphospholipid syndrome; dental care; platelet aggregation; pregnancy complications