title: [Effect of air pollution on pregnancy outcome of women at reproductive age in Xi'an, 2010-2013].
abstract: Objective:To compare the differences in the incidence of adverse pregnancy outcome in different area, and confirm if the incidence of adverse pregnancy outcomes is closely associated with air pollution.Methods:A cross-sectional study was conducted in the central urban area and the rural-urban area of Xi'an through a questionnaire survey conducted among the local reproductive women selected through multistage stratified random sampling during 2010-2013, all the reproductive women surveyed were in pregnancy or had definite pregnancy outcomes.Results:The annual average of SO2concentration in the central urban area was 38-54 μg/m3, higher than that in the rural-urban area (29-43 μg/m3). The annual average NO2concentration in the central urban area was 29-87 μg/m3, higher than that in the rural-urban area (22-42 μg/m3). The incidence of birth defects was higher in the central urban area than in the rural-urban area (2.1%vs.1.0%), the difference was significant (P<0.05). After adjusting for confounding factors, logistic regression analysis showed the incidence of birth defects in the central urban area was still significantly higher than that in the rural-urban area, the difference was significant (P<0.05).Conclusion:The incidence of adverse pregnancy was closely associated with the level of air pollution.
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Health Science Center of Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: L L
authors.initials: LL
authors.lastname: Wang
authors.forename: R H
authors.initials: RH
authors.lastname: Bai
authors.forename: Q
authors.initials: Q
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Yan
mesh_terms: D000397:Air Pollution; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011256:Pregnancy Outcome; D012098:Reproduction; D012424:Rural Population