title: Effects of etomidate and propofol on immune function in patients with lung adenocarcinoma.
abstract: OBJECTIVE
  To investigate the effects of etomidate and propofol on immune function in patients with lung adenocarcinoma.
  
  
  METHODS
  Sixty patients who were scheduled for lung cancer surgery under general anesthesia were studied. The patients were randomly divided into an etomidate total intravenous anesthesia group (group E) and a propofol total intravenous anesthesia group (group P), with 30 cases in each group.
  
  
  RESULTS
  Within group comparison: The percentage of CD4+ in the two groups was significantly reduced at 24 hours post-operation (T2) compared with the percentage before surgery, whereas the percentage of CD8+ was higher at T2. Between group comparison: The CD4+ percentage of group E was higher than that of group P (P< 0.05) at T2, whereas the CD8+ percentage was lower than that of group P (P< 0.05) at T1.
  
  
  CONCLUSIONS
  Using etomidate for anesthesia has less of an effect on immune function in patients with lung adenocarcinoma.
authors.affiliation: Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
authors.forename: Jiapeng
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
authors.forename: Wei
authors.initials: W
authors.lastname: Dong
authors.affiliation: Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.affiliation: Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
authors.forename: Liang
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
authors.forename: Long
authors.initials: L
authors.lastname: Zhan
authors.affiliation: Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
authors.forename: Yifei
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Department of Anesthesiology, Tianjin Chest Hospital Tianjin 300222, P R China.
authors.forename: Jiange
authors.initials: J
authors.lastname: Han
keywords: Etomidate; general anesthesia; immune function; lung adenocarcinoma; propofol