title: Detoxification of ammonium to Nannochloropsis oculata and enhancement of lipid production by mixotrophic growth with acetate.
abstract: In this study, the toxicity of ammonium was removed in the microalga Nannochloropsis oculata by using acetate as a carbon source. Algal biomass and lipid production were significantly enhanced when N. oculata was grew on 0.5-50mM of ammonium and 16-64mM of acetate in mixotrophic conditions. When grown mixotrophically on 1mM of ammonium and 32mM of acetate, the biomass and lipid production reached 543mg/L and 279mg/L respectively, which were 1.5 and 9.4times higher than the levels generated when grown autotrophically on nitrate. This suggests that mixotrophic growth with acetate can be a useful method to enhance microalgal lipid production.
authors.affiliation: Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, PR China.
authors.forename: Weitie
authors.initials: W
authors.lastname: Lin
authors.affiliation: Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, PR China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Li
authors.affiliation: Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, PR China.
authors.forename: Zipeng
authors.initials: Z
authors.lastname: Liao
authors.affiliation: Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, PR China. Electronic address: ljfjf2002@scut.edu.cn.
authors.forename: Jianfei
authors.initials: J
authors.lastname: Luo
mesh_terms: D064751:Ammonium Compounds / Q000032:analysis / Q000302:isolation & purification*; D018533:Biomass; D008658:Inactivation, Metabolic; D008055:Lipids / Q000096:biosynthesis*; D058086:Microalgae / Q000737:chemistry* / Q000254:growth & development / Q000378:metabolism*
chemical_list: D064751:Ammonium Compounds; D008055:Lipids
keywords: Acetate; Ammonium; Detoxification; Nannochloropsis