title: Genomics, proteomics and evolution of dengue virus.
abstract: The genome of a pathogenic organism possesses a specific order of nucleotides that contains not only information about the synthesis and expression of proteomes, which are required for its growth and survival, but also about its evolution. Inhibition of any particular protein, which is required for the survival of that pathogenic organism, can be used as a potential therapeutic target for the development of effective drugs to treat its infections. In this review, the genomics, proteomics and evolution of dengue virus have been discussed, which will be helpful in better understanding of its origin, growth, survival and evolution, and may contribute toward development of new efficient anti-dengue drugs.
authors.forename: Vivek Dhar
authors.initials: VD
authors.lastname: Dwivedi
authors.forename: Indra Prasad
authors.initials: IP
authors.lastname: Tripathi
authors.forename: Ramesh Chandra
authors.initials: RC
authors.lastname: Tripathi
authors.forename: Shiv
authors.initials: S
authors.lastname: Bharadwaj
authors.forename: Sarad Kumar
authors.initials: SK
authors.lastname: Mishra
mesh_terms: D001483:Base Sequence; D018360:Crystallography, X-Ray; D003716:Dengue Virus / Q000235:genetics*; D019143:Evolution, Molecular; D023281:Genomics; D006801:Humans; D008958:Models, Molecular; D010802:Phylogeny; D040901:Proteomics; D065288:Serogroup
keywords: dengue virus; evolution; genomics; proteomics; serotypes