title: Antidepressants triggering suicidal ideation: An area of concern.
abstract: This is a report of four cases of possible suicidal ideation with the use of antidepressants in Indian population. The patients presented to emergency department of a tertiary care hospital with attempted suicide. All of them were prescribed at least one antidepressant. The association of increased suicidal attempts/ideation with antidepressant drugs themselves has been reported in the West, but data in the Indian population are lacking. Antidepressants are widely used not only for treatment of depression but also many other psychiatric illnesses; it is yet unclear whether suicidal ideation is because of these drugs or the progression of the disease. Hence, careful prescribing of these medicines is warranted.
authors.affiliation: Department of Pharmacology, V S Hospital, Ahmedabad, Gujarat, India.
authors.forename: Himali
authors.initials: H
authors.lastname: Rajgadhi
authors.affiliation: Department of Emergency Medicine, V S Hospital, Ahmedabad, Gujarat, India.
authors.forename: Sapna
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Department of Pharmacology, V S Hospital, Ahmedabad, Gujarat, India.
authors.forename: Supriya Deepak
authors.initials: SD
authors.lastname: Malhotra
authors.affiliation: Department of Emergency Medicine, V S Hospital, Ahmedabad, Gujarat, India.
authors.forename: Advait
authors.initials: A
authors.lastname: Thakor
authors.affiliation: Department of Dean and Professor of Orthopaedics, V S Hospital, Ahmedabad, Gujarat, India.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Patel
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology*; D062787:Drug Overdose / Q000175:diagnosis / Q000517:prevention & control / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D059020:Suicidal Ideation; D055815:Young Adult
chemical_list: D000928:Antidepressive Agents
keywords: Antidepressant drugs; emergency department; treatment-emergent suicidal ideation/thought