title: Predictive value of the Movement Assessment Battery for Children - Second Edition at 4 years, for motor impairment at 8 years in children born preterm.
abstract: To assess the predictive validity at 4 years of the Movement Assessment Battery for Children - Second Edition (MABC-2) for motor impairment at 8 years in children born preterm. We also aimed to determine if sex, cognition, medical, or social risks were associated with motor impairment at 8 years or with a change in MABC-2 score between 4 years and 8 years.
  
  
  
  Ninety-six children born at less than 30 weeks' gestation were assessed with the MABC-2 at 4 years and 8 years of age. Motor impairment was defined as less than or equal to the 5th centile. The Differential Ability Scales - Second Edition (DAS-II) was used to measure General Conceptual Ability (GCA) at 4 years, with a score <90 defined as 'below average'.
  
  
  
  There was a strong association between the MABC-2 total standard scores at 4 years and 8 years (59% variance explained, regression coefficient=0.80, 95% confidence interval [CI] 0.69-0.91, p<0.001). The MABC-2 at 4 years had high sensitivity (79%) and specificity (93%) for predicting motor impairment at 8 years. Below average cognition and higher medical risk were associated with increased odds of motor impairment at 8 years (odds ratio [OR]=15.3, 95% CI 4.19-55.8, p<0.001, and OR=3.77, 95% CI 1.28-11.1, p=0.016 respectively). Sex and social risk did not appear to be associated with motor impairment at 8 years. There was little evidence that any variables were related to change in MABC-2 score between 4 years and 8 years.
  
  
  
  The MABC-2 at 4 years is predictive of motor functioning in middle childhood. Below average cognition and higher medical risk may be predictors of motor impairment.
authors.affiliation: Monash University, Clayton, Vic., Australia.|Royal Children's Hospital, Parkville, Vic., Australia.|Murdoch Childrens Research Institute, Parkville, Vic., Australia.
authors.forename: Alison
authors.initials: A
authors.lastname: Griffiths
authors.affiliation: Monash University, Clayton, Vic., Australia.
authors.forename: Prue
authors.initials: P
authors.lastname: Morgan
authors.affiliation: Murdoch Childrens Research Institute, Parkville, Vic., Australia.|University of Melbourne, Parkville, Vic., Australia.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Anderson
authors.affiliation: Murdoch Childrens Research Institute, Parkville, Vic., Australia.|University of Melbourne, Parkville, Vic., Australia.|The Royal Women's Hospital, Parkville, Vic., Australia.
authors.forename: Lex W
authors.initials: LW
authors.lastname: Doyle
authors.affiliation: Murdoch Childrens Research Institute, Parkville, Vic., Australia.|University of Melbourne, Parkville, Vic., Australia.
authors.forename: Katherine J
authors.initials: KJ
authors.lastname: Lee
authors.affiliation: Murdoch Childrens Research Institute, Parkville, Vic., Australia.|University of Melbourne, Parkville, Vic., Australia.|The Royal Women's Hospital, Parkville, Vic., Australia.
authors.forename: Alicia J
authors.initials: AJ
authors.lastname: Spittle
mesh_terms: D002547:Cerebral Palsy / Q000175:diagnosis / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000209:etiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology*; D009069:Movement Disorders / Q000175:diagnosis* / Q000209:etiology*; D011237:Predictive Value of Tests; D047928:Premature Birth / Q000503:physiopathology*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index