title: Metastatic renal clear cell carcinoma to the rectum, lungs, ilium, and lymph nodes: A case report.
abstract: BACKGROUND
  Renal cell carcinoma metastasizing to rectum is very rare, and the unusual metastatic sites should be paid attention to during the follow-up of renal cell carcinoma.
  
  
  METHODS
  We describe a case of a 65-year-old male who was diagnosed with metastatic renal cell carcinoma to rectum 10 years after the right radical nephrectomy. Histopathology and immunohistochemical examinations contribute to making differential diagnosis between rectal metastasis of renal cell carcinoma and primary rectal clear cell carcinoma. Positron emission tomography-computed tomography with fluorodeoxyglucose shows hypermetabolic activity in upper rectum and other sites of metastasis at the same time.
  
  
  CONCLUSIONS
  Possibility of unusual metastatic sites of renal cell carcinoma such as rectum indeed exists, which should not be ignored in the surveillance after resection of the primary tumor.
authors.affiliation: Department of Urology Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Guoyang
authors.initials: G
authors.lastname: Zheng
authors.forename: Hanzhong
authors.initials: H
authors.lastname: Li
authors.forename: Ji
authors.initials: J
authors.lastname: Li
authors.forename: Xuebin
authors.initials: X
authors.lastname: Zhang
authors.forename: Yushi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xingcheng
authors.initials: X
authors.lastname: Wu
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D006801:Humans; D007085:Ilium; D007211:Indoles / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D009392:Nephrectomy; D011758:Pyrroles / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D000077210:Sunitinib
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D011758:Pyrroles; D000077210:Sunitinib