title: Bone marrow biopsies performed by both the powered OnControl drill device and the Jamshidi needle produce adequate specimens.
abstract: OBJECTIVE
  The aim of our study was to evaluate the adequacy and quality of the bone marrow (BM) obtained by OnControl powered drill (P-group) and to compare it with manual procedure (M-group).
  
  
  METHODS
  Retrospective analysis was done on 75 BM specimens; Jamshidi needle (n=44) and OnControl (n=31). Biopsy length after fixation, evaluable marrow length and total area, and fragmentation, aspiration and marrow dropout artefacts were compared.
  
  
  RESULTS
  Biopsies were sufficient for diagnosis in 38/44 cases (86%) in the M-group and in 26/31 cases (83%) in the P-group. The most common reason for suboptimal/inadequate biopsies was subcortical specimens (4/6) in the M-group and aspiration artefact (5/5) in the P-group. Average length after fixation, evaluable marrow length, evaluable marrow area was comparable. Aspiration artefact was minimal (<10%) in the majority of BM samples in the M-group (31/44), while 25/31 BM in the P-group showed >10% aspiration artefact, p<0.0001.
  
  
  CONCLUSIONS
  Our study suggests that quality of biopsy cylinder and adequacy rate of the biopsy is comparable between both devices. OnControl device showed more aspiration artefact.
authors.affiliation: Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors.forename: Sarika
authors.initials: S
authors.lastname: Jain
authors.affiliation: Department of Hemato-Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Enzerra
authors.affiliation: Department of Hemato-Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors.forename: Rohtesh S
authors.initials: RS
authors.lastname: Mehta
authors.affiliation: Department of Hemato-Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors.forename: Roy
authors.initials: R
authors.lastname: Smith
authors.affiliation: Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Djokic
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation; D001853:Bone Marrow / Q000473:pathology*; D001856:Bone Marrow Examination / Q000295:instrumentation / Q000592:standards; D004867:Equipment Design; D006801:Humans; D009339:Needles; D012189:Retrospective Studies; D013048:Specimen Handling / Q000295:instrumentation*
keywords: BONE MARROW; LEUKAEMIA; QUALITY CONTROL