title: Overview of the Role of Vanillin on Redox Status and Cancer Development.
abstract: Bioactive natural products play critical roles in modern drug development, especially anticancer agents. It has been widely reported that various pharmacological activities of such compounds are related to their antioxidant properties. Vanillin is a natural substance widely found in many plant species and often used in beverages, foods, cosmetics, and pharmaceutical products. Antioxidant and anticancer potential have been described for this compound. Considering the importance of vanillin in the area of human health and food and pharmaceuticals sectors, in this review, we discuss the role of vanillin on redox status and its potential contribution to the prevention and the treatment of cancer.
authors.affiliation: Gonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ-BA), Salvador, BA, Brazil.
authors.forename: Daniel Pereira
authors.initials: DP
authors.lastname: Bezerra
authors.affiliation: Department of Pharmaceutical Sciences, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB, Brazil.
authors.forename: Anne Karine Nascimento
authors.initials: AK
authors.lastname: Soares
authors.affiliation: Department of Pharmaceutical Sciences, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB, Brazil.
authors.forename: Damião Pergentino
authors.identifier: 0000-0002-4520-6577
authors.initials: DP
authors.lastname: de Sousa
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000627:therapeutic use / Q000633:toxicity; D000975:Antioxidants / Q000737:chemistry; D017209:Apoptosis; D001547:Benzaldehydes / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity; D001688:Biological Products / Q000737:chemistry; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D010084:Oxidation-Reduction
chemical_list: D000970:Antineoplastic Agents; D000975:Antioxidants; D001547:Benzaldehydes; D001688:Biological Products; C100058:vanillin