title: Efficient access to a designed phosphapalladacycle catalyst via enantioselective catalytic asymmetric hydrophosphination.
abstract: A chiral phosphine auxiliary was generated with excellent ee via catalytic asymmetric hydrophosphination of 3-(naphthalen-1-ylmethylene)pentane-2,4-dione. The subsequent metal complexation of the monophosphine yielded two different coordination complexes depending on the reaction conditions. The ortho-palladation of both coordination complexes resulted in the formation of a single dimeric phosphapalladacycle complex that could be further converted to the monomeric bisacetonitrile derivative. Moreover, the palladium complex exhibits interesting oxophilicity as the stable bisaquo derivative could be isolated and characterized crystallographically. The catalytic potential of the phosphapalladacycle was also demonstrated.
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. pakhing@ntu.edu.sg.
authors.forename: Xi-Rui
authors.initials: XR
authors.lastname: Li
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. pakhing@ntu.edu.sg.
authors.forename: Xiang-Yuan
authors.identifier: http://orcid.org/0000-0002-8678-5659
authors.initials: XY
authors.lastname: Yang
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. pakhing@ntu.edu.sg.
authors.forename: Yongxin
authors.initials: Y
authors.lastname: Li
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. pakhing@ntu.edu.sg.
authors.forename: Sumod A
authors.identifier: http://orcid.org/0000-0002-4150-2408
authors.initials: SA
authors.lastname: Pullarkat
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. pakhing@ntu.edu.sg.
authors.forename: Pak-Hing
authors.identifier: http://orcid.org/0000-0003-3588-1664
authors.initials: PH
authors.lastname: Leung