title: Levator Ani Muscle Defects in Patients With Surgical Failure.
abstract: The objective of the study was to use a well-described system of measuring levator ani (LA) muscle defects from magnetic resonance images to evaluate whether major defects are correlated to an increased risk of surgical failure.
  
  
  
  A retrospective cohort study performed on patients who underwent laparoscopic uterosacral ligament suspension from 2010 to 2012. Surgical failure was defined as a composite score of anatomic bulge beyond the hymen with sensation of bulge or repeat treatment of prolapse via pessary or surgery by 1-year follow-up. Levator ani muscle defects were graded by a score of 0 (no defect), 1 (<50% muscle bulk missing), 2 (>50% muscle bulk missing), or 3 (complete loss of muscle). Total score is the sum from both graded sides, with 0 classified as having no defect, 1 to 3 classified as having minor defects, and 4 to 6 classified as having major defects. Dichotomous values of LA major defects were compared against dichotomous values of surgical outcomes via a contingency table. Fisher exact test was then performed to correlate major defects to surgical success/failure. P value of less than 0.05 was considered statistically significant.
  
  
  
  Sixty-six women met the inclusion criteria. Thirteen (19.6%) patients met the criteria for surgical failure at 1 year. Of the 13, 54% (7) had a major defect, and 46% (6) had a minor or no defect (odds ratio, 1.31; 95% confidence interval, 0.39-4.41; P = 0.762).
  
  
  
  We did not find a statistical correlation to surgical failure after a laparoscopic uterosacral ligament suspension with LA muscle defects on preoperative magnetic resonance images within this specific patient population.
authors.affiliation: From the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL.
authors.forename: Allison M
authors.initials: AM
authors.lastname: Wyman
authors.forename: Kristie A
authors.initials: KA
authors.lastname: Greene
authors.forename: Renee
authors.initials: R
authors.lastname: Bassaly
authors.forename: Lindsey
authors.initials: L
authors.lastname: Hahn
authors.forename: Simon
authors.initials: S
authors.lastname: Patton
authors.forename: Branko
authors.initials: B
authors.lastname: Miladinovic
authors.forename: Lennox
authors.initials: L
authors.lastname: Hoyte
mesh_terms: D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D008022:Ligaments / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D017773:Pelvic Floor / Q000473:pathology; D059952:Pelvic Floor Disorders / Q000473:pathology*; D056887:Pelvic Organ Prolapse / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D012447:Sacrum / Q000601:surgery; D017211:Treatment Failure; D014599:Uterus / Q000601:surgery