title: Multiple Myeloma Associated Chronic Inflammatory Demyelinating Polyradiculoneuropathy: The Importance of Continued Surveillance.
abstract: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease presenting with weakness and numbness in a remitting or chronic progressive course. It is known to have several clinical presentations and several associated diseases. CIDP has been associated with multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), and other paraproteinemias. We present a case of refractory CIDP in which the initial workup for multiple myeloma was negative, and multiple myeloma was then diagnosed two and half years later. Treatment of the multiple myeloma led to clinical improvement. This case is instructive in that perhaps more frequent surveillance for paraproteinemia in patients with CIPD, even after a negative initial workup, could lead to a better clinical outcome.
authors.affiliation: Pulmonary and Critical Care Medicine, Allegheny General Hospital.
authors.forename: Adebayo A
authors.initials: AA
authors.lastname: Fasanya
authors.affiliation: Medicine, Temple University School of Medicine.
authors.forename: Michael F
authors.initials: MF
authors.lastname: Loncharich
authors.affiliation: Pulmonary and Critical Care Medicine, Allegheny General Hospital.
authors.forename: Viral
authors.initials: V
authors.lastname: Gandhi
authors.affiliation: Neurology, Allegheny General Hospital.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Rana
authors.affiliation: Pulmonary and Critical Care Medicine, Allegheny General Hospital.
authors.forename: Marvin
authors.initials: M
authors.lastname: Balaan
keywords: cidp; neuropathy; paraproteinemia; weakness