title: [Association of C reactive protein levels with metabolic syndrome in adults: a population-based study].
abstract: BACKGROUND
  Metabolic syndrome is highly prevalent among adults in Chile and represents a health risk.
  
  
  OBJECTIVE
  To determine the relationship between metabolic syndrome (MetS) and its components, with C reactive protein levels (CRP) as an inflammation marker.
  
  
  METHODS
  The population studied consisted of 736 individuals born in a hospital from Valparaíso Region, aged between 32-38 years at the time of the study. MetS was identified according to the Adult Treatment Panel (ATP) III guidelines and inflammation was measured using ultra-sensitive CRP. This parameter was classified as normal for values from 0 to 3 mg/L, high for values from 3.01 to 10 mg/L and very high for values > 10 mg/L.
  
  
  RESULTS
  Median CRP was in the normal range (1.9 mg/L, interquartile range 0.7-5.2) and was higher among women than men (2.2 and 1.4 mg/L respectively, p < 0.01). Twenty seven percent of participants had MetS. One-fourth had high blood glucose values, one-third had high triglyceride levels and 28% had blood pressure values over those established as normal in MetS. Elevated waist circumference (WC) and low HDL cholesterol were found among almost 50% of participants. A relationship between MetS and high CRP was only found among men with an Odds ratio (OR) of 2.04 (95% confidence intervals (CI): 1.11-3.73). The same association was observed for high triglyceride levels with an OR of 2.02 (CI: 1.17-3.49) and high WC with an OR of 3.89 (CI: 2.06-7.36). Among women, the only relationship observed was between abdominal obesity and very high CRP with an OR of 2. 65 (CI: 1.20-5.84).
  
  
  CONCLUSIONS
  Metabolic syndrome, high triglyceride levels, and abdominal obesity were associated with inflammation only in men.
authors.affiliation: Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Santiago, Chile, pbustos@med.uchile.cl.
authors.forename: Patricia
authors.initials: P
authors.lastname: Bustos
authors.affiliation: Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Santiago, Chile, pbustos@med.uchile.cl.
authors.forename: Bernardita
authors.initials: B
authors.lastname: Rosas
authors.affiliation: Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Santiago, Chile, pbustos@med.uchile.cl.
authors.forename: Pablo
authors.initials: P
authors.lastname: Román
authors.affiliation: Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Santiago, Chile, pbustos@med.uchile.cl.
authors.forename: Juan
authors.initials: J
authors.lastname: Villagrán
authors.affiliation: Departamento de Nutrición, Facultad de Medicina, Universidad de Chile, Santiago, Chile, pbustos@med.uchile.cl.
authors.forename: Hugo
authors.initials: H
authors.lastname: Amigo
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis*; D002677:Chile; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood*; D056128:Obesity, Abdominal / Q000150:complications; D012016:Reference Values; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D012959:Socioeconomic Factors; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides; D002097:C-Reactive Protein