title: [Comparison of colon-cleansing methods in preparation for colonoscopy-comparative of solutions of mannitol and sodium picosulfate].
abstract: OBJECTIVE
  The purpose of the present study is to compare intestinal preparation with mannitol and sodium picosulphate, assessing patient's acceptance, side effects and cleaning capacity.
  
  
  METHODS
  This is a prospective, nom randomized, blind study, in which the evaluator had no information about the preparation applied. The sample obtained was divided into two groups according to the bowel preparation applied, with 153 patients prepared with 10% mannitol and 84 patients with sodium picosulfate. The evaluation of colon preparation was done using the Boston Scale (Boston Bowel Preparation Scale - BBP) through a three-point scoring system for each of the three regions of the colon: right, left and transverse colon.
  
  
  RESULTS
  Of the 237 patients that were evaluated, 146 (61.60%) were female and 91 (38.4%) were male. Regarding the group that used mannitol, 98 were female (64.05%) and 55 were male (35.95%). Among the patients who used sodium picosulfate, 48 were female (57.14%) and 36 were male (42.86%), with no statistical differences between both groups (p> 0.32). Considering that an adequate preparation scores ≥ 6 in the Boston Scale, the bowel cleansing preparation was satisfactory in both groups. 93% of the patients who used mannitol and 81% of the patients who used sodium picosulfate had adequate preparation (score of ≥ 6). Moreover, we consider that the average score in the preparation with Mannitol was 9, while the sodium picosulfate score was 7. There were no significant differences between the two groups.
  
  
  CONCLUSIONS
  There is consensus among authors who state that colonoscopy's safety and success are highly related to the cleansing outcome, regardless of the method used. The same can be observed in the present study, on which both preparations were proved safe and effective for bowel cleansing, according to the Boston scale, as well as accepted by patients and free of complications.
authors.affiliation: Departamento de Endoscopia Gastrointestinal, Escuela de Medicina, Universidad de Sao Paulo. Sao Paulo, Brasil.
authors.forename: Diogo Turiani
authors.initials: DT
authors.lastname: de Moura
authors.affiliation: Departamento de Endoscopia Gastrointestinal, Escuela de Medicina, Universidad de Sao Paulo. Sao Paulo, Brasil.
authors.forename: Hugo
authors.initials: H
authors.lastname: Guedes
authors.affiliation: Universidad de Mogi das Cruzes. Sao Paulo, Brasil.
authors.forename: Verônica
authors.initials: V
authors.lastname: Tortoretto
authors.affiliation: Universidad de Mogi das Cruzes. Sao Paulo, Brasil.
authors.forename: Tayrê Pádua
authors.initials: TP
authors.lastname: Arataque
authors.affiliation: Departamento de Endoscopia Gastrointestinal, Escuela de Medicina, Universidad de Sao Paulo. Sao Paulo, Brasil.
authors.forename: Eduardo Guimarães
authors.initials: EG
authors.lastname: de Moura
authors.affiliation: Departamento de Endoscopia Gastrointestinal, Escuela de Medicina, Universidad de Sao Paulo. Sao Paulo, Brasil.
authors.forename: Juan Pablo
authors.initials: JP
authors.lastname: Román
authors.affiliation: Departamento de Endoscopia Gastrointestinal, Escuela de Medicina, Universidad de Sao Paulo. Sao Paulo, Brasil.
authors.forename: Gustavo Luis
authors.initials: GL
authors.lastname: Rodela
authors.affiliation: Departamento de Endoscopia Gastrointestinal, Escuela de Medicina, Universidad de Sao Paulo. Sao Paulo, Brasil.
authors.forename: Everson L
authors.initials: EL
authors.lastname: Artifon
mesh_terms: D002400:Cathartics / Q000008:administration & dosage* / Q000009:adverse effects; D002951:Citrates / Q000008:administration & dosage* / Q000009:adverse effects; D003113:Colonoscopy; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008353:Mannitol / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage* / Q000009:adverse effects; D017063:Outcome Assessment, Health Care; D010847:Picolines / Q000008:administration & dosage* / Q000009:adverse effects; D011446:Prospective Studies
chemical_list: D002400:Cathartics; D002951:Citrates; D009942:Organometallic Compounds; D010847:Picolines; D008353:Mannitol; C005701:picosulfate sodium