title: Is type D personality an independent risk factor for recurrent myocardial infarction or all-cause mortality in post-acute myocardial infarction patients?
abstract: Background Type D personality refers to a combination of simultaneously high levels of negative affectivity and social inhibition. The present study aimed to examine whether type D personality was independently associated with recurrent myocardial infarction or all-cause mortality in post-acute myocardial infarction patients, using any of the previously proposed methods for measuring type D personality. Design This was a prospective cohort study. Methods Utilising data from the Västmanland Myocardial Infarction Study, 946 post-acute myocardial infarction patients having data on the DS14 instrument used to measure type D personality were followed-up for recurrent myocardial infarction and all-cause mortality until 9 December 2015. Data were analysed using Cox regression, adjusted for established risk factors. Results In total, 133 (14.1%) patients suffered from type D personality. During a mean follow-up time for recurrent myocardial infarction of 5.7 (3.2) years, 166 (17.5%) patients were affected by recurrent myocardial infarction, of which 26 (15.7%) had type D personality, while during a mean follow-up time for all-cause mortality of 6.3 (2.9) years, 321 (33.9%) patients died, of which 42 (13.1%) had type D personality. After adjusting for established risk factors, type D personality was not significantly associated with recurrent myocardial infarction or all-cause mortality using any of the previously proposed methods for measuring type D personality. A weak association was found between the social inhibition part of type D personality and a decreased risk of all-cause mortality, but this association was not significant after taking missing data into account in a multiple imputation analysis. Conclusions No support was found for type D personality being independently associated with recurrent myocardial infarction or all-cause mortality in post-acute myocardial infarction patients, using any of the previously proposed methods for measuring type D personality.
authors.affiliation: 1 Centre for Clinical Research, Uppsala University, Sweden.|2 School of Health, Care and Social Welfare, Malardalen University, Sweden.
authors.forename: Emelie
authors.initials: E
authors.lastname: Condén
authors.affiliation: 1 Centre for Clinical Research, Uppsala University, Sweden.
authors.forename: Andreas
authors.initials: A
authors.lastname: Rosenblad
authors.affiliation: 1 Centre for Clinical Research, Uppsala University, Sweden.
authors.forename: Philippe
authors.initials: P
authors.lastname: Wagner
authors.affiliation: 1 Centre for Clinical Research, Uppsala University, Sweden.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Leppert
authors.affiliation: 3 Department of Neuroscience, Uppsala University, Sweden.
authors.forename: Lisa
authors.initials: L
authors.lastname: Ekselius
authors.affiliation: 1 Centre for Clinical Research, Uppsala University, Sweden.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Åslund
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000401:mortality* / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012008:Recurrence; D012042:Registries; D018570:Risk Assessment; D012720:Severity of Illness Index; D019467:Subacute Care / Q000379:methods; D016019:Survival Analysis; D013548:Sweden; D064415:Type D Personality
keywords: All-cause mortality; recurrent myocardial infarction; type D personality