title: The end of measles and congenital rubella: an achievable dream?
abstract: Despite substantial progress towards measles and rubella control, outbreaks continue to threaten elimination goals worldwide.
  
  
  
  This paper aims to document progress towards the global eradication of measles and rubella. In particular, it investigates the major challenges faced by Italy in reaching the elimination goals.
  
  
  
  A review of the most important literature was carried out. Furthermore, a systematic review of the scientific literature on measles and rubella in the Italian setting was performed for the period 2000-2016.
  
  
  
  In the National Plan 2010-2015, Italy renewed its commitment to eliminate measles and rubella by 2015. However, Italy recently experienced a high measles burden (2,205 cases in 2013, 1,694 in 2014). Between June 2015 and May 2016, 515 cases were reported, accounting for 28% all cases in Europe. Immunization coverage decreased in recent years, with no Region reaching the 95% target. The systematic review included a total of 175 papers, with an upward trend in the number of published articles, which demonstrates an increasing interest in the field of measles and rubella. The review highlights the need to improve the commitment of the Italian Regions to the elimination goals; to promote Supplementary Immunization Activities (SIAs); to improve the communication skills of health care workers; to improve the health literacy of citizens; and to enhance integrated measles and rubella surveillance.
  
  
  
  Elimination of measles and rubella in Italy will require a substantial improvement in both commitment of the 21 Regions and activity of the whole country towards the WHO goals.
authors.affiliation: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Adamo
authors.affiliation: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Sturabotti
authors.affiliation: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
authors.forename: E
authors.initials: E
authors.lastname: D'Andrea
authors.affiliation: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Baccolini
authors.affiliation: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Romano
authors.affiliation: Office of Infectious Diseases and Prophylaxis, Ministry of Health, Rome, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Iannazzo
authors.affiliation: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Marzuillo
authors.affiliation: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy - Chairperson of the Italian National Verification Committee for measles and rubella elimination.
authors.forename: P
authors.initials: P
authors.lastname: Villari
mesh_terms: D060740:Disease Eradication; D004196:Disease Outbreaks / Q000517:prevention & control*; D005060:Europe / Q000453:epidemiology; D005260:Female; D006291:Health Policy; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008457:Measles / Q000453:epidemiology / Q000517:prevention & control*; D008458:Measles Vaccine / Q000008:administration & dosage* / Q000276:immunology; D012409:Rubella / Q000453:epidemiology / Q000517:prevention & control*; D012410:Rubella Syndrome, Congenital / Q000453:epidemiology / Q000517:prevention & control*; D012411:Rubella Vaccine / Q000008:administration & dosage* / Q000276:immunology; D014611:Vaccination / Q000379:methods; D014944:World Health Organization
chemical_list: D008458:Measles Vaccine; D012411:Rubella Vaccine
keywords:  Measles; Congenital rubella; Elimination Italy; Rubella