title: Drug sensitivity pattern of variousStaphylococcusspecies isolated at a tertiary care hospital.
abstract: BACKGROUND
  Staphylococcus aureusand otherStaphylococcusspecies are important pathogenic organisms and are responsible for various hospital infections. These are the predominant organisms found in pus and blood culture isolates. Infections arising due to these bacterial isolates are difficult to treat because of developing multidrug resistance.
  
  
  METHODS
  Over a 1-year period at a tertiary care hospital laboratory, 524 Staphylococci species were isolated from pus, blood and urine samples and species-level identification was done.
  
  
  RESULTS
  S. aureusformed the predominant species (70.8%) followed by coagulase-negativeStaphylococcus(CoNS) (29.20%).S. aureus(91%) was the main isolate from pus samples; however, CoNS was isolated in equally higher proportion in blood culture (63.58%). Among the CoNS,Staphylococcus hemolyticuswas the main isolate (9.3%). β-Lactamase production, alteration of PBP and MLSB resistance were seen in variable degrees in different species.
  
  
  CONCLUSIONS
  CoNS group of Staphylococci is becoming an important cause of infection at tertiary care centres. The increased multidrug resistance among variousStaphylococcusspecies is a cause of great concern and requires adequate measures to prevent the spread of these microorganisms in the hospital and the community.
authors.affiliation: Senior Adviser (Pathology), Military Hospital Meerut, UP, India.
authors.forename: Lavan
authors.initials: L
authors.lastname: Singh
authors.affiliation: Associate Professor, Dept of Community Medicine, Armed Forces Medical College, Pune 411040, India.
authors.forename: M P
authors.initials: MP
authors.lastname: Cariappa
authors.affiliation: Assistant Professor (Microbiology), Dr. D. Y. Patil Medical College, Pimpri, Pune, India.
authors.forename: N K
authors.initials: NK
authors.lastname: Das
keywords: Antibiotic resistance; Coagulase-negative Staphylococcus; Macrolide–lincosamide–streptogramin-B antibiotic resistance; Staphylococcus aureus