title: Fine particulate matter on hospital admissions for acute exacerbation of chronic obstructive pulmonary disease in southwestern Taiwan during 2006-2012.
abstract: This study explored the effects of PM2.5on hospital admissions (HAs) for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in southwestern Taiwan. Data on HAs for AECOPD, pollutants, and meteorological variables were obtained from the National Health Insurance Research Database and Environmental Protection Administration. The relative risks (RRs) of HAs for AECOPD was estimated using the Quasi-Poisson generalized additive model. A total of 38,715 HAs for AECOPD were recorded. The average daily HAs for AECOPD and mean 24-h average level of PM2.5were 15.2 and 38.8 µg/m3, respectively. For both single and multiple pollutant (adjusted for O3and NO2) models, increased AECOPD admissions were significantly associated with PM2.5during cold season, with the RRs for every 10 µg/m3increase in PM2.5being 1.02 (95% CI = 1.007-1.040) at lag 0-1 in single-pollutant, and 1.02 (95 % CI = 1.001-1.042) at lag 0 day in multiple pollutant model. People 65 years of age and older had higher risk of HAs for AECOPD after PM2.5exposure. The RRs of PM2.5on HAs for AECOPD were robust after adjusting for O3and NO2. Findings reveal an association between PM2.5and HAs for AECOPD in southwestern Taiwan, particularly during cold season.
authors.affiliation: a Department of Nursing , Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|b Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|c Division of Pulmonary and Critical Care Medicine , Chang Gung Memorial Hospital Chiayi Branch , Puzi City , Taiwan, ROC.
authors.forename: Su-Lun
authors.initials: SL
authors.lastname: Hwang
authors.affiliation: c Division of Pulmonary and Critical Care Medicine , Chang Gung Memorial Hospital Chiayi Branch , Puzi City , Taiwan, ROC.|d Department of Respiratory Care , Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|e Department of Respiratory Therapy , Chang Gung University , Taoyuan , Taiwan, ROC.
authors.forename: Yu-Ching
authors.initials: YC
authors.lastname: Lin
authors.affiliation: a Department of Nursing , Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|b Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.
authors.forename: Su-Er
authors.initials: SE
authors.lastname: Guo
authors.affiliation: a Department of Nursing , Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|b Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.
authors.forename: Chiang-Ting
authors.initials: CT
authors.lastname: Chou
authors.affiliation: a Department of Nursing , Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|d Department of Respiratory Care , Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|f Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University , Taoyuan , Taiwan, ROC.
authors.forename: Chieh-Mo
authors.initials: CM
authors.lastname: Lin
authors.affiliation: b Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.|d Department of Respiratory Care , Chang Gung University of Science and Technology , Puzi City , Taiwan, ROC.
authors.forename: Miao-Ching
authors.initials: MC
authors.lastname: Chi
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000393:Air Pollutants / Q000032:analysis / Q000633:toxicity*; D004781:Environmental Exposure / Q000032:analysis; D004784:Environmental Monitoring; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D010316:Particle Size; D052638:Particulate Matter / Q000032:analysis / Q000633:toxicity*; D029424:Pulmonary Disease, Chronic Obstructive / Q000139:chemically induced / Q000453:epidemiology*; D012621:Seasons; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter
keywords: Fine particulate matter; acute exacerbation of chronic obstructive pulmonary disease; hospital admissions; population-based study; season