title: AuPt Alloy Nanostructures with Tunable Composition and Enzyme-like Activities for Colorimetric Detection of Bisulfide.
abstract: Tuning the enzyme-like activity and studying the interaction between biologically relevant species and nano-enzymes may facilitate the applications of nanostructures in mimicking natural enzymes. In this work, AuPt alloy nanoparticles (NPs) with varying compositions were prepared through a facile method by co-reduction of Au3+and Pt2+in aqueous solutions. The composition could be tuned easily by adjusting the molar ratios of added Pt2+to Au3+. It was found that both peroxidase-like and oxidase-like activity of AuPt alloy NPs were highly dependent on the alloy compositions, which thus suggesting an effective way to tailor their catalytic properties. By investigating the inhibitory effects of HS-on the enzyme-like activity of AuPt alloy NPs and natural enzyme, we have developed a method for colorimetric detection of HS-and evaluation of the inhibiting effects of inhibitors on natural and artificial enzymes. In addition, the responsive ability of this method was influenced largely by the composition: AuPt alloy NPs show much lower limit of detection for HS-than Pt NPs while Pt NPs show wider linear range than AuPt alloy NPs. This study suggests the facile way not only for synthesis of alloy nanostructures, but also for tuning their catalytic activities and for use in bioanalysis.
authors.affiliation: Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, College of Advanced Materials and Energy, Institute of Surface Micro and Nano Materials, Xuchang University, Henan 461000, P.R. China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: He
authors.affiliation: Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, College of Advanced Materials and Energy, Institute of Surface Micro and Nano Materials, Xuchang University, Henan 461000, P.R. China.
authors.forename: Xiangna
authors.initials: X
authors.lastname: Han
authors.affiliation: Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, College of Advanced Materials and Energy, Institute of Surface Micro and Nano Materials, Xuchang University, Henan 461000, P.R. China.
authors.forename: Huimin
authors.initials: H
authors.lastname: Jia
authors.affiliation: Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, College of Advanced Materials and Energy, Institute of Surface Micro and Nano Materials, Xuchang University, Henan 461000, P.R. China.
authors.forename: Junhui
authors.initials: J
authors.lastname: Cai
authors.affiliation: Wenzhou Institute of biomaterials and engineering, CNITECH, CAS, Zhejiang 325001, P.R. China.|Institute of biomaterials and engineering, Wenzhou Medical University, Zhejiang 325001, P.R. China.
authors.forename: Yunlong
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, College of Advanced Materials and Energy, Institute of Surface Micro and Nano Materials, Xuchang University, Henan 461000, P.R. China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Zheng
mesh_terms: D000497:Alloys / Q000378:metabolism*; D040761:Biomimetic Materials / Q000378:metabolism; D002623:Chemistry Techniques, Analytical; D003124:Colorimetry / Q000379:methods*; D004798:Enzymes / Q000378:metabolism; D006046:Gold / Q000378:metabolism; D049329:Nanostructures; D010984:Platinum / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000032:analysis*
chemical_list: D000497:Alloys; D004798:Enzymes; D013438:Sulfhydryl Compounds; D010984:Platinum; D006046:Gold