title: [The role of Sabin inactivated poliovirus vaccine in the final phase of global polio eradication].
abstract: Global polio eradication has entered its final phase, but still faces enormous challenges. The Polio Eradication and Endgame Strategic Plan (2013-2018) set the target for making the world polio-free by 2018. Meanwhile, the World Heath Organization Global Action Plan (GAP Ⅲ) recommended that polioviruses be stored under strict conditions after eradication of the wild poliovirus. At least one dose of inactivated poliovirus vaccine (IPV) would be required for each newborn baby in the world to ensure successful completion of the final strategy and GAP Ⅲ. The Sabin IPV has a high production safety and low production cost, compared with the wild-virus IPV and, therefore, can play an important role in the final stage of global polio eradication.
authors.affiliation: Institute of Medical Biology, Chinese Academy of Medical Scence and Peking Union Medical College, Kunming 650118, China.
authors.forename: S Z
authors.initials: SZ
authors.lastname: Dong
authors.forename: W B
authors.initials: WB
authors.lastname: Zhu
mesh_terms: D060740:Disease Eradication / Q000379:methods; D014943:Global Health; D006801:Humans; D017589:Immunization Programs; D007223:Infant; D011051:Poliomyelitis / Q000517:prevention & control*; D017955:Poliovirus / Q000145:classification*; D011054:Poliovirus Vaccine, Inactivated / Q000008:administration & dosage* / Q000276:immunology; D011055:Poliovirus Vaccine, Oral / Q000008:administration & dosage* / Q000276:immunology; D014611:Vaccination
chemical_list: D011054:Poliovirus Vaccine, Inactivated; D011055:Poliovirus Vaccine, Oral