title: Testicular cancer in Down syndrome with spinal cord metastases.
abstract: A 22-year-old male patient with Down syndrome was referred to our hospital with a vast left testicular mass. He underwent a left radical inguinal orchiectomy, and a histopathological examination of the mass showed a yolk sac tumor invading the epididymis. The patient was discharged in a satisfactory condition. Sixteen days later, the patient presented again complaining of lower limb weakness. Magnetic resonance imaging of the spine showed metastatic lesions compressing the dorsal spine, and he underwent emergency surgical decompression. The histopathology of the metastatic lesions revealed a yolk sac subtype which was identical to his primary testicular tumor.
authors.affiliation: Department of Urology, King Abdullah Medical City, Makkah, Saudi Arabia.
authors.forename: Turky
authors.initials: T
authors.lastname: Almouhissen
authors.affiliation: Department of Urology, King Abdullah Medical City, Makkah, Saudi Arabia.
authors.forename: Hattan
authors.initials: H
authors.lastname: Badr
authors.affiliation: Department of Urology, King Abdullah Medical City, Makkah, Saudi Arabia.
authors.forename: Bassam
authors.initials: B
authors.lastname: AlMatrafi
authors.affiliation: Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
authors.forename: Noor
authors.initials: N
authors.lastname: Alessa
authors.affiliation: Department of Urology, King Abdullah Medical City, Makkah, Saudi Arabia; Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
authors.forename: Anmar
authors.initials: A
authors.lastname: Nassir
keywords: Bone metastases; Down syndrome; seminoma; spinal cord injury; testicular tumor; testis; trisomy