title: Daily associations between PTSD, drinking, and self-appraised alcohol-related problems.
abstract: Alcohol dependence (AD) and posttraumatic stress disorder (PTSD) are highly comorbid, yet limited research has focused on PTSD and daily drinking as they relate to self-appraised alcohol-related problems. In treatment contexts, patients' appraisals of alcohol-related problems have implications for assessment, intervention strategies, and prognosis. This study investigated the moderating effect of within-person (daily symptoms) and between-person (overall severity) differences in PTSD on the association between daily drinking and same-day alcohol-related problems. Participants with comorbid AD and PTSD (N = 86) completed 1 week of Interactive Voice Recognition data collection, and logistic and γ-adjusted multilevel models were used to estimate odds and magnitude of self-appraised alcohol-related problems. Results revealed that both within-person and between-person PTSD moderated the association between number of drinks and severity of self-appraised problems. As within-person and between-person PTSD symptoms increased, there was a weaker association between number of drinks consumed and perceived alcohol-related problems. Contrasts further revealed that on nondrinking and light-drinking days, PTSD (both daily symptoms and overall severity) was positively associated with ratings of alcohol-related problems. However, PTSD was not associated with alcohol-related problems on heavier drinking days. In conclusion, more severe PTSD is associated with a less directly contingent relationship between drinking quantity and perceived alcohol-related problems. These findings suggest the importance of further investigations of this moderating effect as well as clinical treatment of comorbid AD and severe PTSD with functional analysis of drinking. (PsycINFO Database Record
authors.affiliation: Mid-Atlantic Mental Illness Research Education and Clinical Center (MIRECC).
authors.forename: Sarah M
authors.identifier: 0000-0002-1028-6028
authors.initials: SM
authors.lastname: Wilson
authors.affiliation: VISN 20 MIRECC, VA Puget Sound Health Care System.
authors.forename: Marketa
authors.initials: M
authors.lastname: Krenek
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Duke University Medical Center.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Dennis
authors.affiliation: VA Puget Sound Health Care System.
authors.forename: Samantha S
authors.initials: SS
authors.lastname: Yard
authors.affiliation: VISN 20 MIRECC, VA Puget Sound Health Care System.
authors.forename: Kendall C
authors.initials: KC
authors.lastname: Browne
authors.affiliation: Center of Excellence in Substance Abuse Treatment & Education (CESATE), VA Puget Sound Health Care System.
authors.forename: Tracy L
authors.initials: TL
authors.lastname: Simpson
mesh_terms: D000328:Adult; D019973:Alcohol-Related Disorders / Q000175:diagnosis* / Q000453:epidemiology; D015897:Comorbidity; D059026:Diagnostic Self Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis* / Q000453:epidemiology; D055815:Young Adult