title: Profound T-cell lymphopenia associated with prenatal exposure to purine antagonists detected by TREC newborn screening.
authors.affiliation: Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, Calif. Electronic address: ckuo@mednet.ucla.edu.
authors.forename: Caroline Y
authors.initials: CY
authors.lastname: Kuo
authors.affiliation: Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, Calif.
authors.forename: Maria I
authors.initials: MI
authors.lastname: Garcia-Lloret
authors.affiliation: ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah; Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Patricia
authors.initials: P
authors.lastname: Slev
authors.affiliation: Department of Allergy and Immunology, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: John F
authors.initials: JF
authors.lastname: Bohnsack
authors.affiliation: Department of Allergy and Immunology, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Karin
authors.initials: K
authors.lastname: Chen
mesh_terms: D001372:Aza Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007223:Infant; D007231:Infant, Newborn; D018655:Lymphocyte Count; D008231:Lymphopenia / Q000175:diagnosis* / Q000235:genetics; D038041:Lymphopoiesis / Q000187:drug effects; D008297:Male; D015122:Mercaptopurine / Q000009:adverse effects* / Q000627:therapeutic use; D015997:Neonatal Screening; D057089:Pathology, Molecular; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000175:diagnosis*; D011687:Purines / Q000037:antagonists & inhibitors*; D011948:Receptors, Antigen, T-Cell / Q000235:genetics*; D016511:Severe Combined Immunodeficiency / Q000175:diagnosis*; D013601:T-Lymphocytes / Q000502:physiology*; D014481:United States
chemical_list: D001372:Aza Compounds; D007166:Immunosuppressive Agents; D011687:Purines; D011948:Receptors, Antigen, T-Cell; D015122:Mercaptopurine; C030985:purine