title: Long-term Results of Small-incision Lenticule Extraction in High Myopia.
abstract: OBJECTIVE
  To evaluate two-year results of small-incision lenticule extraction (SMILE) for correction of high myopia.
  
  
  METHODS
  Forty-five eyes of 35 patients with mean spherical equivalent (SE) of -7.10±0.95 D who underwent routine SMILE by a single surgeon and were followed for at least 2 years were analyzed by retrospective chart review. SMILE was performed with a Visumax femtosecond laser (Carl Zeiss Meditec, Jena, Germany). Follow-up intervals were at 1, 6, 12, and 24 months after surgery. Uncorrected and best corrected distance visual acuity (CDVA), corneal wavefront measurements, and all complications were recorded.
  
  
  RESULTS
  After 2 years, 86% of eyes with plano target had an uncorrected distant visual acuity (VA) of 20/20 or better. Two percent of eyes lost 1 line of CDVA, while 32% gained 1 line. The mean SE after 2 years was -0.30±0.50 D. Corneal total high-order aberrations (HOA) increased from 0.43 to 0.92 μm at postoperative 12 months. There were metallic foreign bodies at the corneal interface in 1 eye of 1 patient which caused no decrease in VA.
  
  
  CONCLUSIONS
  SMILE for high myopia seems safe and effective in light of two-year follow-up results. The procedure caused a moderate increase in HOA.
authors.affiliation: Prof. Dr. N. Reşat Belger Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yıldırım
authors.affiliation: Prof. Dr. N. Reşat Belger Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Cengiz
authors.initials: C
authors.lastname: Alagöz
authors.affiliation: Kağıthane State Hospital, Ophthalmology Clinic, İstanbul, Turkey.
authors.forename: Abdülvahit
authors.initials: A
authors.lastname: Demir
authors.affiliation: Prof. Dr. N. Reşat Belger Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Onur
authors.initials: O
authors.lastname: Ölçücü
authors.affiliation: Prof. Dr. N. Reşat Belger Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Özveren
authors.affiliation: Prof. Dr. N. Reşat Belger Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Ağca
authors.affiliation: Prof. Dr. N. Reşat Belger Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Engin Bilge
authors.initials: EB
authors.lastname: Özgürhan
authors.affiliation: Prof. Dr. N. Reşat Belger Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Demirok
keywords: Small-incision lenticule extraction; high myopia; high-order aberrations