title: A Hazard Analysis of Risk Factors of Mortality in Individuals Who Inject Drugs in Denver CO.
abstract: Despite multiple risk factors for mortality among People Who Inject Drugs (PWID), more research is warranted that examines sub-populations within PWID. Mortality data from PWID participating in longitudinal HIV prevention research in Denver were obtained from The Colorado Department of Public Health and Environment. Risk factors for both all-cause and acute-toxicity related mortality were analyzed using Cox proportional hazards regression. Two-thousand seven individuals were interviewed at baseline. Eighty-six individuals died during the time frame of the study, 58 of which were due to acute-toxicity. Disabled (HR = 3.3, p < 0.001), gay/lesbian-identified (HR = 2.6, p = 0.03), white race/ethnicity (HR = 2.4, p = 0.003), and use of a shared cooker (HR = 2.1, p = 0.01) were important adjusted risk factors. These suggest that drug and HIV interventions should utilize techniques that can address the needs of marginalized populations in addition to HIV drug risk behaviors.
authors.affiliation: Project Safe, Department of Psychiatry, School of Medicine, University of Colorado Denver, 1557 Ogden Street, Denver, CO, 80218, USA. Jonathan.davis@ucdenver.edu.
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Davis
authors.affiliation: Project Safe, Department of Psychiatry, School of Medicine, University of Colorado Denver, 1557 Ogden Street, Denver, CO, 80218, USA.
authors.forename: Katie
authors.initials: K
authors.lastname: Suleta
authors.affiliation: Project Safe, Department of Psychiatry, School of Medicine, University of Colorado Denver, 1557 Ogden Street, Denver, CO, 80218, USA.
authors.forename: Karen F
authors.initials: KF
authors.lastname: Corsi
authors.affiliation: Project Safe, Department of Psychiatry, School of Medicine, University of Colorado Denver, 1557 Ogden Street, Denver, CO, 80218, USA.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Booth
mesh_terms: D000163:Acquired Immunodeficiency Syndrome; D000328:Adult; D002423:Cause of Death; D003120:Colorado; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D015658:HIV Infections / Q000401:mortality / Q000517:prevention & control; D006801:Humans; D013287:Illicit Drugs / Q000633:toxicity*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D016485:Needle Sharing / Q000706:statistics & numerical data; D016016:Proportional Hazards Models; D012307:Risk Factors; D000072339:Sexual and Gender Minorities / Q000706:statistics & numerical data; D015819:Substance Abuse, Intravenous / Q000401:mortality*
chemical_list: D013287:Illicit Drugs
keywords: Disabled; Gay/lesbian identification; Mortality risk; PWID