title: Acute Liver Injury and Failure.
abstract: Acute liver injury and acute liver failure are syndromes characterized by a rapid loss of functional hepatocytes in a patient with no evidence of pre-existing liver disease. A variety of inciting causes have been identified, including toxic, infectious, neoplastic, and drug-induced causes. This article reviews the pathophysiology and clinical approach to the acute liver injury/acute liver failure patient, with a particular emphasis on the diagnostic evaluation and care in the acute setting.
authors.affiliation: Emergency and Critical Care Medicine, Department of Clinical Studies, Matthew J. Ryan Veterinary Hospital of the University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104, USA. Electronic address: vthawley@upenn.edu.
authors.forename: Vincent
authors.initials: V
authors.lastname: Thawley
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D002415:Cats; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary*; D004035:Diet Therapy / Q000379:methods / Q000662:veterinary; D004283:Dog Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D004285:Dogs; D017114:Liver Failure, Acute / Q000209:etiology / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary*; D011379:Prognosis; D014812:Vitamin K / Q000627:therapeutic use
chemical_list: D014812:Vitamin K
keywords: Coagulopathy; Hepatic encephalopathy; Liver failure; Liver jury