title: Recent Update on the Role of Chinese Material Medica and Formulations in Diabetic Retinopathy.
abstract: Diabetes mellitus is one of the most frequent endocrine disorders, affecting populations worldwide. Diabetic retinopathy (DR) is the most frequent microvascular complication of diabetes in patients aged 20 and over. Major complications of DR include intraocular neovascularization, inter-retinal edema, hemorrhage, exudates and microaneurysms. Therefore, timely medical attention and prevention are required. At present, laser-assisted therapy and other operational procedures are the most common treatment for DR. However, these treatments can cause retinal damage and scarring. Also, use of the majority of traditional medicines is not supported by clinical evidence. However, due to accumulating scientific evidence, traditional natural medications may assist in delaying or preventing the progression of DR. This review focuses on evidence for the role of traditional natural medicines and their mechanisms of action and pharmacological test results in relation to the progression of DR.
authors.affiliation: Department of Biotechnology, Konkuk University, Chungju 380-701, Korea. sandeepbcp@gmail.com.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Vasant More
authors.affiliation: Department of Biotechnology, Konkuk University, Chungju 380-701, Korea. kis5497@kku.ac.kr.
authors.forename: In-Su
authors.initials: IS
authors.lastname: Kim
authors.affiliation: Department of Biotechnology, Konkuk University, Chungju 380-701, Korea. choidk@kku.ac.kr.
authors.forename: Dong-Kug
authors.initials: DK
authors.lastname: Choi
mesh_terms: D000328:Adult; D000818:Animals; D003930:Diabetic Retinopathy / Q000188:drug therapy* / Q000473:pathology; D018450:Disease Progression; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008419:Materia Medica / Q000627:therapeutic use*; D008516:Medicine, Chinese Traditional / Q000379:methods; D009389:Neovascularization, Pathologic / Q000473:pathology / Q000517:prevention & control*; D010946:Plants, Medicinal / Q000737:chemistry* / Q000145:classification; D012160:Retina / Q000187:drug effects / Q000473:pathology
chemical_list: D004365:Drugs, Chinese Herbal; D008419:Materia Medica
keywords: diabetes; herbal; medicine; retinopathy; traditional