title: Aminophosphine Oxides: A Platform for Diversified Functions.
abstract: This review summarizes significant contributions reported on aminophosphine oxides (AmPOs), specifically those containing at least one amino group present as amino substituents on α- and β-carbons including direct P-N bond containing molecules. AmPOs have additional 'N' site(s), including highly basic 'P=O' groups, and these features make favor smooth and unexpected behavior. The most striking manifestations of flexibility of AmPOs are that they are exciting ligand systems for the coordination chemistry of actinides, and their involvement in catalytic organic reactions including enantioselective opening of meso-epoxides, addition of silyl enol ethers, allylation with allyltributylstannane, etc. The diverse properties of the AmPOs and their metal complexes demonstrate both the scope and complexity of these systems, depending on the basicity of phosphoryl group, and nature of the substituents on the pentavalent tetracoordinate phosphorus atom and metal. Two components key to understanding the challenges of actinide separations are detailed here, namely, previously described separation methods, and recent investigations into the fundamental coordination chemistry of actinides. Both are aimed at probing the critical features necessary for improved selectivity of separations. This review leads to the conclusion that, although many AmPOs have already been discovered and developed over the past century, many opportunities nevertheless exist for further developments towards new extraction processes and new catalytic materials by fine tuning the electronic and steric properties of substituents on the central phosphorus atom.
authors.affiliation: Department of Chemistry, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632 014, India.
authors.forename: E Veerashekhar
authors.initials: EV
authors.lastname: Goud
authors.affiliation: Department of Chemistry, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632 014, India. asrkrishna@vit.ac.in.
authors.forename: Akella
authors.initials: A
authors.lastname: Sivaramakrishna
authors.affiliation: Department of Chemistry, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632 014, India.
authors.forename: Kari
authors.initials: K
authors.lastname: Vijayakrishna
mesh_terms: D015394:Molecular Structure; D010087:Oxides / Q000138:chemical synthesis / Q000737:chemistry*; D010720:Phosphines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D010087:Oxides; D010720:Phosphines; C000629094:aminophosphine
keywords: Actinide separation; Aminophosphine oxide; Application; Coordination behavior; Synthetic route