title: N-Heterocyclic Carbene-Catalyzed [4 + 2] Cyclization of Saturated Carboxylic Acid with o-Quinone Methides through in Situ Activation: Enantioselective Synthesis of Dihydrocoumarins.
abstract: An N-heterocyclic carbene (NHC)-catalyzed formal [4 + 2] synthesis of dihydrocoumarins was realized from saturated carboxylic acids and o-quinone methides via an in situ activation strategy. This protocol results in excellent diastereoselectivity and enantioselectivity and good yields and uses readily available and inexpensive starting materials.
authors.affiliation: Jangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, Jiangsu 221116, P. R. China.
authors.forename: Yuanfeng
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Jangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, Jiangsu 221116, P. R. China.
authors.forename: Jian
authors.initials: J
authors.lastname: Pan
authors.affiliation: Jangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, Jiangsu 221116, P. R. China.
authors.forename: Jingjiao
authors.initials: J
authors.lastname: Dong
authors.affiliation: Jangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, Jiangsu 221116, P. R. China.
authors.forename: Chenxia
authors.initials: C
authors.lastname: Yu
authors.affiliation: Jangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, Jiangsu 221116, P. R. China.
authors.forename: Tuanjie
authors.initials: T
authors.lastname: Li
authors.affiliation: Jangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, Jiangsu 221116, P. R. China.
authors.forename: Xiang-Shan
authors.identifier: 0000-0002-0077-7819
authors.initials: XS
authors.lastname: Wang
authors.affiliation: Xuzhou Institute of Architectural Technology , Xuzhou, Jiangsu 221116, China.
authors.forename: Shide
authors.initials: S
authors.lastname: Shen
authors.affiliation: Jangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, Jiangsu 221116, P. R. China.
authors.forename: Changsheng
authors.identifier: 0000-0002-0185-2366
authors.initials: C
authors.lastname: Yao