title: Access to N-cyanosulfoximines by transition metal-free iminations of sulfoxides.
abstract: A transition metal-free synthesis of N-cyanosulfoximines from sulfoxides using N-chlorosuccinimide (NCS) as oxidising agent and cyanamide as nucleophilic amine source is reported. The products are obtained in moderate to excellent yields. The protocol enables an easy access to N-cyanosulfoximines from readily available starting materials under inversion of configuration at a preexisting stereogenic center.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany. carsten.bolm@oc.rwth-aachen.de.
authors.forename: C A
authors.initials: CA
authors.lastname: Dannenberg
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany. carsten.bolm@oc.rwth-aachen.de.
authors.forename: L
authors.initials: L
authors.lastname: Fritze
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany. carsten.bolm@oc.rwth-aachen.de.
authors.forename: F
authors.initials: F
authors.lastname: Krauskopf
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany. carsten.bolm@oc.rwth-aachen.de.
authors.forename: C
authors.identifier: http://orcid.org/0000-0001-9415-9917
authors.initials: C
authors.lastname: Bolm