title: Hepatitis E Virus (HEV) Infection in Anti-HEV Immunoglobulin G-Carrying Patients After Successful Hepatitis C Virus Treatment: Reactivation or Reinfection?
abstract: Although hepatitis E virus (HEV) is regarded as a self-limiting infection and anti-HEV antibodies seem to protect against reinfection, its pathogenesis is not well established. We describe 2 cases of acute symptomatic HEV infection after hepatitis C therapy in patients carrying anti-HEV immunoglobulin G antibodies, raising 2 major questions: reactivation or reinfection?
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: Antonio
authors.initials: A
authors.lastname: Rivero-Juarez
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: Mario
authors.initials: M
authors.lastname: Frias
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: Pedro
authors.initials: P
authors.lastname: Lopez-Lopez
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: María
authors.initials: M
authors.lastname: de Los Angeles Risalde
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: Teresa
authors.initials: T
authors.lastname: Brieva
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: Isabel
authors.initials: I
authors.lastname: Machuca
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: Angela
authors.initials: A
authors.lastname: Camacho
authors.affiliation: Servicio de Análisis Clínico, Hospital Universitario Reina Sofía de Córdoba, Instituto Maimonides de Investigación Biomédica de Córdoba, Universidad de Córdoba; and.
authors.forename: Antonio
authors.initials: A
authors.lastname: Martinez-Peinado
authors.affiliation: Departamento de Sanidad Animal, Universidad de Córdoba, Spain.
authors.forename: Jose Carlos
authors.initials: JC
authors.lastname: Gomez-Villamandos
authors.affiliation: Unidad de Enfermedades Infecciosas and.
authors.forename: Antonio
authors.initials: A
authors.lastname: Rivero
mesh_terms: D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D000998:Antiviral Agents / Q000627:therapeutic use; D060085:Coinfection; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D006508:Hepatitis Antibodies / Q000097:blood / Q000276:immunology*; D006526:Hepatitis C / Q000188:drug therapy / Q000821:virology; D016751:Hepatitis E / Q000175:diagnosis / Q000276:immunology* / Q000821:virology*; D016752:Hepatitis E virus / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D008297:Male; D008875:Middle Aged; D019562:Viral Load; D014775:Virus Activation
chemical_list: D000998:Antiviral Agents; D006508:Hepatitis Antibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M
keywords: HIV; hepatitis C; hepatitis E; reactivation.; reinfection