title: 3D Printing of Aniline Tetramer-Grafted-Polyethylenimine and Pluronic F127 Composites for Electroactive Scaffolds.
abstract: Electroactive hydrogel scaffolds are fabricated by the 3D-printing technique using composites of 30% Pluronic F127 and aniline tetramer-grafted-polyethylenimine (AT-PEI) copolymers with various contents from 2.5% to 10%. The synthesized AT-PEI copolymers can self-assemble into nanoparticles with the diameter of ≈50 nm and display excellent electroactivity due to AT conjugation. The copolymers are then homogeneously distributed into 30% Pluronic F127 solution by virtue of the thermosensitivity of F127, denoted as F/AT-PEI composites. Macroscopic photographs of latticed scaffolds elucidate their excellent printability of F/AT-PEI hydrogels for the 3D-printing technique. The conductivities of the printed F/AT-PEI scaffolds are all higher than 2.0 × 10-3S cm-1, which are significantly improved compared with that of F127 scaffold with only 0.94 × 10-3S cm-1. Thus, the F/AT-PEI scaffolds can be considered as candidates for application in electrical stimulation of tissue regeneration such as repair of muscle and cardiac nerve tissue.
authors.affiliation: Beijing Engineering Research Center of Printed Electronics, Beijing Institute of Graphic Communication, Beijing, 102600, China.
authors.forename: Shi-Lei
authors.initials: SL
authors.lastname: Dong
authors.affiliation: Beijing Engineering Research Center of Printed Electronics, Beijing Institute of Graphic Communication, Beijing, 102600, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Han
authors.affiliation: Beijing Engineering Research Center of Printed Electronics, Beijing Institute of Graphic Communication, Beijing, 102600, China.
authors.forename: Cai-Xia
authors.initials: CX
authors.lastname: Du
authors.affiliation: Beijing Engineering Research Center of Printed Electronics, Beijing Institute of Graphic Communication, Beijing, 102600, China.
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Wang
authors.affiliation: Beijing Engineering Research Center of Printed Electronics, Beijing Institute of Graphic Communication, Beijing, 102600, China.
authors.forename: Lu-Hai
authors.initials: LH
authors.lastname: Li
authors.affiliation: Beijing Engineering Research Center of Printed Electronics, Beijing Institute of Graphic Communication, Beijing, 102600, China.|Department of Chemistry and Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing, 100084, China.
authors.forename: Yen
authors.initials: Y
authors.lastname: Wei
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D004553:Electric Conductivity; D020100:Hydrogels / Q000138:chemical synthesis* / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry; D010316:Particle Size; D020442:Poloxamer / Q000138:chemical synthesis / Q000737:chemistry*; D011094:Polyethyleneimine / Q000138:chemical synthesis / Q000737:chemistry*; D066330:Printing, Three-Dimensional; D013499:Surface Properties
chemical_list: D000814:Aniline Compounds; D020100:Hydrogels; D020442:Poloxamer; D011094:Polyethyleneimine; C023650:aniline
keywords: 3D printing; AT-PEI copolymer; Pluronic F127; electroactive scaffolds