title: Plasmids of Distinct IncK Lineages Show Compatible Phenotypes.
abstract: IncK plasmids are some of the main carriers ofblaCTX-M-14andblaCMY-2genes and show high similarity to other plasmids belonging to the I complex, including IncB/O plasmids. Here, we studied the phylogenetic relationship of 37 newly sequenced IncK and IncB/O plasmids. We show that IncK plasmids can be divided into two compatible lineages named IncK1 and IncK2.
authors.affiliation: Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
authors.forename: Marta
authors.initials: M
authors.lastname: Rozwandowicz
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Michael S M
authors.initials: MS
authors.lastname: Brouwer
authors.affiliation: Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
authors.forename: Aldert L
authors.initials: AL
authors.lastname: Zomer
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Alex
authors.initials: A
authors.lastname: Bossers
authors.affiliation: Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Frank
authors.initials: F
authors.lastname: Harders
authors.affiliation: Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.|Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Dik J
authors.initials: DJ
authors.lastname: Mevius
authors.affiliation: Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.|Wageningen Bioveterinary Research, Lelystad, The Netherlands.
authors.forename: Jaap A
authors.initials: JA
authors.lastname: Wagenaar
authors.affiliation: Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands j.hordijk@uu.nl.
authors.forename: Joost
authors.initials: J
authors.lastname: Hordijk
mesh_terms: D003227:Conjugation, Genetic; D004926:Escherichia coli / Q000145:classification / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology; D029968:Escherichia coli Proteins / Q000235:genetics* / Q000378:metabolism; D015870:Gene Expression; D006801:Humans; D010641:Phenotype; D010802:Phylogeny; D010957:Plasmids / Q000737:chemistry / Q000145:classification* / Q000378:metabolism; D017422:Sequence Analysis, DNA; D014169:Transformation, Bacterial; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
chemical_list: D029968:Escherichia coli Proteins; C000621415:beta-lactamase CTX-M-14, E coli; D001618:beta-Lactamases; C000605810:beta-lactamase CMY-2, E coli
keywords: IncK; incompatibility; plasmid