title: Heck functionalization of an asymmetric aza-BODIPY core: synthesis of far-red infrared probes for bioimaging applications.
abstract: As part of our ongoing work on the synthesis of a new class of plant hormones named Strigolactones (SLs) and their analogues, we became interested in tracing bioactive molecules with red emitting BODIPY fluorophores in order to unravel signaling and distribution of SLs in plants. In this paper we report on an unprecedented Heck functionalization of azadipyrromethenes (aza-DIPY) which allows for the introduction of suitable functional groups to convert aza-BODIPY in bioconjugate complexes useful for untangling biological processes.
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Stefano
authors.initials: S
authors.lastname: Parisotto
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Beatrice
authors.initials: B
authors.lastname: Lace
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Emma
authors.initials: E
authors.lastname: Artuso
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Chiara
authors.initials: C
authors.lastname: Lombardi
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Annamaria
authors.identifier: http://orcid.org/0000-0003-2622-2798
authors.initials: A
authors.lastname: Deagostino
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Roberto
authors.initials: R
authors.lastname: Scudu
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Claudio
authors.initials: C
authors.lastname: Garino
authors.affiliation: Dipartimento di Biotecnologie Molecolari e Scienze per la Salute, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Medana
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Torino, via P. Giuria 7, 10125 Torino, Italy. cristina.prandi@unito.it.
authors.forename: Cristina
authors.identifier: http://orcid.org/0000-0001-9510-8783
authors.initials: C
authors.lastname: Prandi
mesh_terms: D017360:Arabidopsis / Q000737:chemistry; D001372:Aza Compounds / Q000737:chemistry / Q000493:pharmacokinetics*; D001896:Boron Compounds / Q000737:chemistry / Q000493:pharmacokinetics*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry / Q000493:pharmacokinetics*; D015394:Molecular Structure; D055668:Photochemical Processes; D018517:Plant Roots / Q000737:chemistry; D019265:Spectroscopy, Near-Infrared; D014018:Tissue Distribution
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001372:Aza Compounds; D001896:Boron Compounds; D005456:Fluorescent Dyes