title: The study protocol for a non-randomized controlled clinical trial using a genotype-guided strategy in a dataset of patients who undergone percutaneous coronary intervention with stent.
abstract: This article contains data related to the research article entitled "Results of genotype-guided antiplatelet therapy in patients undergone percutaneous coronary intervention with stent" (J. Sánchez-Ramos, C.L. Dávila-Fajardo, P. Toledo Frías, X. Díaz Villamarín, L.J. Martínez-González, S. Martínez Huertas, F. Burillo Gómez, J. Caballero Borrego, A. Bautista Pavés, M.C. Marín Guzmán, J.A. Ramirez Hernández, C. Correa Vilches, J. Cabeza Barrera, 2016) (1). This data article reports, for the first time, about the non-randomized clinical trial protocol that check ifCYP2C19/ABCB1genotype-guided strategy in which the choice of antiplatelet therapy is based on the genetic test, reduces the rates of cardiovascular events and bleeding compared to a non-tailored strategy in patients undergone percutaneous coronary intervention (PCI) with stent. The data included in this article are: design and setting of the study, study population, inclusion and exclusion criteria, definition of the intervention, objectives, variables (baseline characteristics and during the follow-up), study procedures, collection and treatment of the biological sample, genotyping, withdrawal criteria, sample size, statistic analysis, ethical aspects, information sheet and consent form. The authors confirm that this study has been registered in Eudra CT (Eudra CT: 2016-001294-33).
authors.affiliation: Department of Clinical Pharmacy, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Cristina Lucía
authors.initials: CL
authors.lastname: Dávila-Fajardo
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Sánchez-Ramos
authors.affiliation: Department of Clinical Pharmacy, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Xando Diaz-
authors.initials: XD
authors.lastname: Villamarín
authors.affiliation: Genomics Unit, Centre for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Andalusian Regional Government, Health Sciences Technology Park, Granada, Spain.
authors.forename: Luis Javier
authors.initials: LJ
authors.lastname: Martínez-González
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Pablo Toledo
authors.initials: PT
authors.lastname: Frías
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Susana Martínez
authors.initials: SM
authors.lastname: Huertas
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Francisco Burillo
authors.initials: FB
authors.lastname: Gómez
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Juan Caballero
authors.initials: JC
authors.lastname: Borrego
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Alicia Bautista
authors.initials: AB
authors.lastname: Pavés
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Mª Carmen Marín
authors.initials: MC
authors.lastname: Guzmán
authors.affiliation: Department of Clinical Pharmacy, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: José Antonio Ramirez
authors.initials: JA
authors.lastname: Hernández
authors.affiliation: Department of Cardiology, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Concepción Correa
authors.initials: CC
authors.lastname: Vilches
authors.affiliation: Department of Clinical Pharmacy, Granada University Hospital, Institute for Biomedical Research, ibs., Granada, Spain.
authors.forename: Jose Cabeza
authors.initials: JC
authors.lastname: Barrera
keywords: Clinical trial protocol