title: Primitive neuroectodermal tumour of the cervix: a rare diagnosis.
abstract: A 48-year-old woman presented with symptoms of lower abdominal pain and vaginal discharge for 6 months. Clinical examination and pelvic ultrasound scan suggested a diagnosis of infected Gartner's cyst, for which she underwent vaginal cystectomy. However, histopathology and immunohistochemistry revealed a diagnosis of primitive neuroectodermal tumour of the cervix. Further investigations revealed the stage to be FIGO IIIB, which was inoperable. She received neoadjuvant chemotherapy (vincristine, adriamycin, cyclophosphamide alternating with ifosfamide, cisplatin and etoposide, every 21 days), but the tumour did not respond to treatment and she was started on radiotherapy with definitive intent (55.8 Gray in 31 fractions over 6.2 weeks). A PET-CT performed 2 months after completion of radiotherapy showed complete response, and she is now receiving adjuvant chemotherapy.
authors.affiliation: Department of Radiation Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India.
authors.forename: Irfan
authors.initials: I
authors.lastname: Ahmad
authors.affiliation: Department of Radiation Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India.
authors.forename: Kundan Singh
authors.initials: KS
authors.lastname: Chufal
authors.affiliation: Department of Medical Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Bhargava
authors.affiliation: Department of Radiation Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India.
authors.forename: Irfan
authors.initials: I
authors.lastname: Bashir
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D035583:Rare Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy