title: Cooperative Lewis acid-onium salt catalysis as tool for the desymmetrization of meso-epoxides.
abstract: Epoxide desymmetrizations by bromide are very rare despite the large synthetic potential of chiral bromohydrins. Herein we present a new concept for epoxide desymmetrizations in which a bifunctional Lewis acid/ammonium salt catalyst allows for efficient enantioselective epoxide ring openings by Br-. With acetylbromide as a Br-source bromohydrin esters are formed.
authors.affiliation: Universität Stuttgart, Institut für Organische Chemie, Pfaffenwaldring 55, 70569 Stuttgart, Germany. rene.peters@oc.uni-stuttgart.de.
authors.forename: Florian
authors.initials: F
authors.lastname: Broghammer
authors.affiliation: Universität Stuttgart, Institut für Organische Chemie, Pfaffenwaldring 55, 70569 Stuttgart, Germany. rene.peters@oc.uni-stuttgart.de.
authors.forename: Daniel
authors.initials: D
authors.lastname: Brodbeck
authors.affiliation: Universität Stuttgart, Institut für Organische Chemie, Pfaffenwaldring 55, 70569 Stuttgart, Germany. rene.peters@oc.uni-stuttgart.de.
authors.forename: Thorsten
authors.initials: T
authors.lastname: Junge
authors.affiliation: Universität Stuttgart, Institut für Organische Chemie, Pfaffenwaldring 55, 70569 Stuttgart, Germany. rene.peters@oc.uni-stuttgart.de.
authors.forename: René
authors.identifier: http://orcid.org/0000-0002-6668-4017
authors.initials: R
authors.lastname: Peters