title: [Relationship of consequences of anastomotic insufficiency and bacterial flora of oral cavity in patients with esophageal and cardia cancer].
abstract: BACKGROUND
  In the course of anastomotic insufficiency following resection of esophageal cancers the bacterial compound of the esophageal substance has a remarkable, presumable role in the outcome of complications.
  
  
  OBJECTIVE
  The purpose of this study is to compare the consequences of the anastomotic leak with the bacterial flora of patients' oral cavity.
  
  
  METHODS
  In this prospective study a total of 131 patients were investigated directly before the surgical intervention taking a bacterial sample. Bacterial flora of patients' oral cavity was analysed; and the correlation between the consequences of the anastomotic leak and the content of the bacterial flora was examined.
  
  
  RESULTS
  Pathogenic bacteria in the oral microflora in 50 cases (38.2%) was found. Statistically significant, moderate correlation was found between the severity of the complication and the incidence of pathogenic bacteria (rs= 0.553; p≤0.05).
  
  
  CONCLUSIONS
  Pathogenic agent in the microbial flora might induce higher risk and more severe outcome in case of anastomotic leakage and it might be evaluated as a determinative factor. Consideration of the bacterial flora of the oral cavity requires more attention in the preoperative preparation than before and it demands the change of the current practice. Orv. Hetil., 2017, 158(1), 25-30.
authors.affiliation: Általános Orvostudományi Kar, I. Sebészeti Klinika, Semmelweis Egyetem Budapest, Üllői út 78., 1082.
authors.forename: Ákos
authors.initials: Á
authors.lastname: Balázs
authors.affiliation: Általános Orvostudományi Kar, Tudományos Diákkör, Semmelweis Egyetem Budapest.
authors.forename: Beáta
authors.initials: B
authors.lastname: Winkler
authors.affiliation: Klinikai Mikrobiológiai, Diagnosztikai Laboratórium, Laboratóriumi Medicina Intézet Budapest.
authors.forename: Katalin
authors.initials: K
authors.lastname: Kristóf
authors.affiliation: Általános Orvostudományi Kar, I. Sebészeti Klinika, Semmelweis Egyetem Budapest, Üllői út 78., 1082.
authors.forename: László
authors.initials: L
authors.lastname: Harsányi
authors.affiliation: Általános Orvostudományi Kar, I. Sebészeti Klinika, Semmelweis Egyetem Budapest, Üllői út 78., 1082.
authors.forename: Lívia
authors.initials: L
authors.lastname: Bokor
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects; D057868:Anastomotic Leak / Q000382:microbiology*; D002299:Cardia / Q000382:microbiology* / Q000601:surgery; D004938:Esophageal Neoplasms / Q000382:microbiology* / Q000601:surgery; D016629:Esophagectomy / Q000009:adverse effects*; D006801:Humans; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000382:microbiology* / Q000601:surgery
keywords: anastomosiselégtelenség; anastomotic leakage; esophageal tumor; műtéti előkészítés; nyelőcsőtumor; oral bacterial flora; preoperative preparation; szájüregi baktériumflóra