title: Ecthyma gangrenosum, a skin manifestation of Pseudomonas aeruginosa sepsis in a previously healthy child: A case report.
abstract: BACKGROUND
  Ecthyma gangrenosum (Eg) is a necrotic lesion that is mostly seen in immunocompromised patients. It reflects a severe sepsis, possibly caused by Pseudomonas aeruginosa (Pa).
  
  
  METHODS
  A healthy 3-year-old girl admitted to the Pediatric Emergency Department presented a sepsis-associated purpura with neurological and respiratory distress.
  
  
  METHODS
  An empiric antibiotherapy (anti-meningococcal) was prescribed.
  
  
  METHODS
  Forty-eight hours after admission, blood and wound cultures were positive for Pa. As a result, the decision was made to change the antibiotic therapy.Unfortunately, on day 3, the patient died. Exhaustive immunologic tests are presently being carried out.
  
  
  RESULTS
  Eg caused by Pa is uncommon in healthy children, and purpura sepsis is usually caused by Neisseria meningitides infection.
  
  
  CONCLUSIONS
  Eg should be recognized rapidly so that the appropriate treatment can be prescribed as quickly as possible.
authors.affiliation: Pediatric Hospitals of Nice CHU-Lenval, Nice, France.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Biscaye
authors.forename: Diane
authors.initials: D
authors.lastname: Demonchy
authors.forename: Mickael
authors.initials: M
authors.lastname: Afanetti
authors.forename: Audrey
authors.initials: A
authors.lastname: Dupont
authors.forename: Herve
authors.initials: H
authors.lastname: Haas
authors.forename: Antoine
authors.initials: A
authors.lastname: Tran
mesh_terms: D002675:Child, Preschool; D004473:Ecthyma / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D011552:Pseudomonas Infections / Q000150:complications*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D018805:Sepsis / Q000382:microbiology*