title: Precipitation SELEX: identification of DNA aptamers for calcium phosphate materials synthesis.
abstract: DNA aptamers that enhance calcium phosphate mineral formation were identified using a novel precipitation SELEX method. The evolved DNA library was substantially enriched in G nucleotides and in predicted G-quadruplex structures, suggesting their importance in the mechanism of mineralization. This work could readily be extended to provide additional novel DNA aptamers for materials synthesis.
authors.affiliation: Department of Chemistry and Physics, Emmanuel College, 400 The Fenway, Boston, MA, USA. gerdoar@emmanuel.edu.
authors.forename: K R
authors.initials: KR
authors.lastname: Baillargeon
authors.affiliation: Department of Chemistry and Physics, Emmanuel College, 400 The Fenway, Boston, MA, USA. gerdoar@emmanuel.edu.
authors.forename: K
authors.initials: K
authors.lastname: Meserve
authors.affiliation: Department of Chemistry and Physics, Emmanuel College, 400 The Fenway, Boston, MA, USA. gerdoar@emmanuel.edu.
authors.forename: S
authors.initials: S
authors.lastname: Faulkner
authors.affiliation: Department of Chemistry and Physics, Emmanuel College, 400 The Fenway, Boston, MA, USA. gerdoar@emmanuel.edu.
authors.forename: S
authors.initials: S
authors.lastname: Watson
authors.affiliation: Department of Chemistry and Physics, Emmanuel College, 400 The Fenway, Boston, MA, USA. gerdoar@emmanuel.edu.
authors.forename: H
authors.initials: H
authors.lastname: Butts
authors.affiliation: Department of Biology, Emmanuel College, 400 The Fenway, Boston, MA, USA.
authors.forename: P
authors.initials: P
authors.lastname: Deighan
authors.affiliation: Department of Chemistry and Physics, Emmanuel College, 400 The Fenway, Boston, MA, USA. gerdoar@emmanuel.edu.
authors.forename: A E
authors.identifier: http://orcid.org/0000-0001-7133-679X
authors.initials: AE
authors.lastname: Gerdon