title: Settling a Nervous Stomach: The Neural Regulation of Enteric Cancer.
abstract: The nervous system is emerging as a regulator of malignancy. In this issue of Cancer Cell, Hayakawa et al. demonstrate a feedforward signaling loop in which tumor-derived nerve growth factor promotes enteric tumor innervation, and recruited nerves drive cancer growth through acetylcholine-regulated Wnt signaling and stimulation of further NGF release.
authors.affiliation: Department of Neurology, Stanford University, Stanford, CA 94305, USA. Electronic address: mmonje@stanford.edu.
authors.forename: Michelle
authors.initials: M
authors.lastname: Monje
mesh_terms: D006801:Humans; D009369:Neoplasms; D015398:Signal Transduction; D013270:Stomach