title: Effects of age after laparoscopic right colectomy for cancer: Are there any specific outcomes?
abstract: BACKGROUND
  Laparoscopic approach in colorectal surgery has demonstrated to give advantages in terms of postoperative outcomes, particularly in high-risk patients. The aim was to assess the impact of patients' age on the short-term outcomes after laparoscopic right colectomy for cancer.
  
  
  METHODS
  From January 2004 to September 2014, all patients who underwent laparoscopic right colectomy for cancer in a single institution were divided into four groups (A: <64 years; B: 65-74 years; C: 75-84 years; D ≥85 years). Risk factors for postoperative complications were determined on multivariable analysis.
  
  
  RESULTS
  Laparoscopic right colectomy was performed in 507 patients, including 171 (33.7%) in A, 168 (33.1%) in B, 131 (25.8) in C and 37 (7.4%) in D. Patients in Group C and Group D had higher ASA score (p<0.0001) and presented more frequently with anaemia (20.6% and 29.7%, p=0.001). Stages III and IV were more frequently encountered in groups C and D. Overall morbidity was 27.5% without any difference in the four groups (24.5%, 29.1%, 7.5% and 18.4% respectively, p=0.58). The rate of minor complications (such as wound infection or postoperative ileus) was higher in Group D compared to other groups (p=0.05). The only independent variable correlated with postoperative morbidity was intraoperative blood transfusion (OR 2.82; CI 95% 1.05-4.59, p<0.0001).
  
  
  CONCLUSIONS
  The present series suggests that patient's age did not significantly jeopardize the postoperative outcomes after laparoscopic right colectomy for cancer.
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Denet
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France. Electronic address: david.fuks@imm.fr.
authors.forename: David
authors.initials: D
authors.lastname: Fuks
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Francesca
authors.initials: F
authors.lastname: Cocco
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Chopinet
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Marcel
authors.initials: M
authors.lastname: Abbas
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Cyprian
authors.initials: C
authors.lastname: Costea
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Hugues
authors.initials: H
authors.lastname: Levard
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Perniceni
authors.affiliation: Department of Digestive Disease, Institute Mutualiste Montsouris, Paris Descartes University, Paris, France.
authors.forename: Brice
authors.initials: B
authors.lastname: Gayet
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000453:epidemiology*; D001803:Blood Transfusion; D003082:Colectomy / Q000009:adverse effects*; D003110:Colonic Neoplasms / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000601:surgery*; D005260:Female; D005602:France; D006801:Humans; D045823:Ileus / Q000453:epidemiology; D010535:Laparoscopy / Q000379:methods; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology*; D012307:Risk Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: Colorectal cancer; Elderly patients; Laparoscopic right colectomy; Postoperative outcomes; Transfusion