title: Zika Virus Infection and Guillain-Barré Syndrome in Three Patients from Suriname.
abstract: We present three patients from Suriname who were diagnosed with Guillain-Barré syndrome (GBS) during the Zika virus (ZIKV) outbreak in this country. One patient had a positive ZIKV urine real-time RT-PCR (qRT-PCR) result. The other two patients had a negative ZIKV urine qRT-PCR but a positive virus neutralization test and presence of IgG antibodies against ZIKV in the serum. Considering the evidence of a past ZIKV infection and absence of evidence for recent infections with the most common preceding infections of GBS, it is very likely that these GBS cases were triggered by ZIKV.
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Thomas
authors.initials: T
authors.lastname: Langerak
authors.affiliation: Department of Neurology, Academic Hospital Paramaribo , Paramaribo , Suriname.
authors.forename: Harvey
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Neurology, St. Vincentius Hospital , Paramaribo , Suriname.
authors.forename: Mark
authors.initials: M
authors.lastname: Baptista
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Laura
authors.initials: L
authors.lastname: Doornekamp
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Tessa
authors.initials: T
authors.lastname: Kerkman
authors.affiliation: Diagnostic Laboratory, Academic Hospital Paramaribo , Paramaribo , Suriname.
authors.forename: John
authors.initials: J
authors.lastname: Codrington
authors.affiliation: Diagnostic Laboratory, Academic Hospital Paramaribo , Paramaribo , Suriname.
authors.forename: Jimmy
authors.initials: J
authors.lastname: Roosblad
authors.affiliation: Department of Internal Medicine, Academic Hospital Paramaribo , Paramaribo , Suriname.
authors.forename: Stephen G S
authors.initials: SG
authors.lastname: Vreden
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Erwin
authors.initials: E
authors.lastname: De Bruin
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Ramona
authors.initials: R
authors.lastname: Mögling
authors.affiliation: Department of Neurology, Erasmus Medical Center, Rotterdam, Netherlands; Department of Immunology, Erasmus Medical Center, Rotterdam, Netherlands.
authors.forename: Bart C
authors.initials: BC
authors.lastname: Jacobs
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Suzan D
authors.initials: SD
authors.lastname: Pas
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Corine H
authors.initials: CH
authors.lastname: GeurtsvanKessel
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Chantal B E M
authors.initials: CB
authors.lastname: Reusken
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Marion P
authors.initials: MP
authors.lastname: Koopmans
authors.affiliation: Department of Viroscience, Erasmus Medical Center , Rotterdam , Netherlands.
authors.forename: Eric C M
authors.initials: EC
authors.lastname: Van Gorp
authors.affiliation: Department of Neurology, Academic Hospital Paramaribo , Paramaribo , Suriname.
authors.forename: Henk
authors.initials: H
authors.lastname: Alberga
keywords: Flavivirus infections; Guillain–Barré syndrome; Zika virus; acute flaccid paralysis; emerging infectious disease