title: Rapid development of a mycotic aneurysm of the intracranial artery secondary toScedosporium apiospermumsinusitis.
abstract: An 85-year-old man complained of a 2-month history of pain on the left side of his face. Brain computed tomography (CT) and magnetic resonance imaging/magnetic resonance angiography did not clearly show any intracranial abnormality and only showed fluid effusion in his left sphenoid sinus. Filamentous fungi were detected from the left sphenoid sinus specimen. The isolate wasScedosporium apiospermum. He was empirically treated with voriconazole, to which the isolate was susceptible. His consciousness decreased rapidly. Urgent 3D-CT angiography revealed an intracranial aneurysm near the left sphenoid sinus. Despite urgent coil embolization, the aneurysm ruptured, and he died.
authors.affiliation: Center for Infectious Diseases, Nara Medical University, Shijo 840, Kashihasa, Nara, Japan.
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Ogawa
authors.affiliation: Department of Infectious Diseases, Nara City Hospital, Nara, Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Sato
authors.affiliation: Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Tashiro
authors.affiliation: Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Miyazaki
authors.affiliation: Department of Neurosurgery, Nara City Hospital, Nara, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Nagata
authors.affiliation: Department of Neurology, Nara City Hospital, Nara, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Takahashi
authors.affiliation: Center for Infectious Diseases, Nara Medical University, Shijo 840, Kashihasa, Nara, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Kasahara
authors.affiliation: Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Izumikawa
authors.affiliation: Department of Microbiology and Infectious Diseases, Nara Medical University, Nara, Japan.
authors.forename: Hisakazu
authors.initials: H
authors.lastname: Yano
authors.affiliation: Center for Infectious Diseases, Nara Medical University, Shijo 840, Kashihasa, Nara, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Mikasa
keywords: Central nervous system infection; Mycotic aneurysm; Scedosporium apiospermum