title: The response of weaned piglets to dietary valine and leucine.
abstract: Valine (Val) is considered to be the fifth-limiting amino acid in a maize-soyabean meal diet for pigs. Excess leucine (Leu) levels often occur in commercial diets, which may attenuate the effect of Val deficiency because of an increased oxidation of Val. The objective of the present experiment was to determine the effect of increasing concentrations of Leu on the response of young piglets to dietary Val. In all, 75 Large White×Landrace entire male pigs, 44 days of age and with a mean starting weight of 13.5 kg, were used. Three of these were sacrificed at the start to determine their mean initial chemical composition. A summit feed first limiting in Val was serially diluted with a non-protein diluent to produce a series of five digestible Val concentrations of 11.9, 10.1, 8.3, 6.6 and 4.8 g/kg, with a sixth treatment being added to test that the feeds were limiting in Val. Three identical Val series, each with six levels of Val, were supplemented with increasing amounts of Leu (23, 45 and 67 g/kg), thus 18 treatments in total. All pigs were killed at the end of the trial after 18 days for analysis of water, protein, lipid and ash in the carcass. The levels of Val and Leu and their interaction significantly influenced all the measurements taken in the trial. Daily gain in liveweight, water and protein, and feed conversion efficiency all increased with dietary Val content, whereas feed intake decreased as both Val and Leu contents increased. The deleterious effect of increased Leu on feed intake and growth was more marked at lower levels of Val. Supplementing the feed with the lowest Val content with additional Val largely overcame the effect of excess Leu. The efficiency of utilisation of Val for protein growth was unaffected by the level of Leu in the feed, the primary response to excess Leu being a reduction in feed intake. An intake of around 9 g Val/day yielded maximal protein growth during the period from 44 to 62 days of age in pigs of the genotype used in this trial.
authors.affiliation: 1Department Animal and Wildlife Science, Faculty Natural and Agricultural Sciences,University of Pretoria,Pretoria 0002,South Africa.
authors.forename: F
authors.initials: F
authors.lastname: Meyer
authors.affiliation: 1Department Animal and Wildlife Science, Faculty Natural and Agricultural Sciences,University of Pretoria,Pretoria 0002,South Africa.
authors.forename: C
authors.initials: C
authors.lastname: Jansen van Rensburg
authors.affiliation: 2School of Agricultural, Earth and Environmental Sciences,University of KwaZulu-Natal,Pietermaritzburg 3209,South Africa.
authors.forename: R M
authors.initials: RM
authors.lastname: Gous
mesh_terms: D000821:Animal Feed; D000818:Animals; D004032:Diet / Q000662:veterinary; D019587:Dietary Supplements; D004435:Eating / Q000187:drug effects; D007930:Leucine / Q000378:metabolism / Q000494:pharmacology*; D008297:Male; D013025:Glycine max; D013552:Swine / Q000502:physiology*; D014633:Valine / Q000378:metabolism / Q000494:pharmacology*; D014886:Weaning; D003313:Zea mays
chemical_list: D007930:Leucine; D014633:Valine
keywords: feed intake; growth; leucine; pigs; valine