title: Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection.
abstract: Cutaneous hyperpigmentation is a recognized adverse effect of chronic minocycline use occurring in up to 50% of patients. In this report we present a rare case of extensive skin hyperpigmentation involving both lower extremities in a patient receiving long term minocycline. The patient was receiving minocycline as suppression for chronic prosthetic joint infection. Risk factors associated with minocycline-induced cutaneous pigmentation (MICH) will be reviewed.
authors.affiliation: Division of Infectious Disease, Mayo Clinic College of Medicine, Rochester, MN, United States.
authors.forename: Hadi
authors.initials: H
authors.lastname: Berbari
authors.affiliation: Division of Infectious Disease, Mayo Clinic College of Medicine, Rochester, MN, United States.
authors.forename: Elie F
authors.initials: EF
authors.lastname: Berbari
authors.affiliation: Division of Infectious Disease, Mayo Clinic College of Medicine, Rochester, MN, United States.
authors.forename: Irene G
authors.initials: IG
authors.lastname: Sia