title: 1-year course of fatigue in patients on chronic hemodialysis.
abstract: OBJECTIVE
  Fatigue is common in end-stage renal disease patients receiving hemodialysis, reduces significantly their quality of life and is associated with all-cause and cardiac-related mortality. Unfortunately, little is known about the course of fatigue in patients on chronic hemodialysis.
  
  
  METHODS
  The Vitality Subscale of the SF-36 (SF-36 VS), Short-Form Health Survey, was administered to 45 patients in January (T1), June (T2) and November (T3) 2015.
  
  
  RESULTS
  The score of the SF-36 VS did not differ significantly among T1, T2 and T3. Similarly, the 1-year course of the SF-36 Vitality Subscale score did not differ significantly among T1, T2 and T3 after stratification of patients for sex, age, BMI, IADL and Charlson. Between T1 and T2, 21 out of 45 patients (46.6%) changed their fatigue status: 8 fatigued patients became not-fatigued and 13 not-fatigued patients became fatigued. Between T2 and T3, 12 out of 45 (26.6%) patients changed their fatigue status: 5 fatigued patients became not-fatigued and 7 not-fatigued patients became fatigued. Between T1 and T3, 19 out of 45 patients (42.2%) changed their fatigue status: 6 fatigued patients became not-fatigued and 13 not-fatigued became fatigued.
  
  
  CONCLUSIONS
  The present study is the first to identify variations in fatigue status among patients on chronic hemodialysis during 1-year course. These findings suggest to frequently assess the presence and severity of fatigue in patients on chronic hemodialysis.
authors.affiliation: Hemodialysis Unit, Institute of Clinical Surgery, Catholic University of the Sacred Heart, Rome, Italy. maubosso@tin.it.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bossola
authors.affiliation: Department of Clinical Chemistry, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Di Stasio
authors.affiliation: Department of Gerontology, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Antocicco
authors.affiliation: Hemodialysis Unit, Institute of Clinical Surgery, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Gilda
authors.initials: G
authors.lastname: Pepe
authors.affiliation: Department of Gerontology, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Marzetti
authors.affiliation: Hemodialysis Unit, Institute of Clinical Surgery, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Vulpio
mesh_terms: D000328:Adult; D000368:Aged; D005221:Fatigue / Q000209:etiology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors
keywords: Course; Fatigue; Hemodialysis; Longitudinal