title: The Efficacy of Intravitreal Bevacizumab in Vitreous Hemorrhage of Diabetic Subjects.
abstract: OBJECTIVE
  To evaluate the efficacy of intravitreal bevacizumab (IVB) in the resolution of vitreous hemorrhage (VH) secondary to proliferative diabetic retinopathy (PDR).
  
  
  METHODS
  Seventy eyes of 70 patients (43 male, mean age 55.6±12.2 years) diagnosed with VH secondary to PDR were evaluated retrospectively. Demographic characteristics of the patients, baseline and final clinical results, and the interventions the patients were subject to were recorded. The patients who received IVB injections (group 1, n=29) were compared to those who did not receive injections (group 2, n=41) in terms of VH clearance time and surgery rates.
  
  
  RESULTS
  The mean follow-up time was 14.5±6.1 months in group 1 and 18.4±9.6 months in group 2 (p=0.185). The mean visual acuity was similar between the groups at baseline and at the last visit (for all p>0.05). Panretinal photocoagulation could be applied in 86% of subjects in group 1 and in 58% in group 2 2 within the first month (p=0.016). VH clearance time was not different between the groups (2.3±2.1 months in group 1 and 3.4±2.6 months in group 2, p=0.146). The number of subjects requiring surgery was 7 (24%) in group 1 and 20 (48.8%) in group 2 (p=0.048).
  
  
  CONCLUSIONS
  IVB was found effective in cases with VH secondary to PDR in terms of reducing the need for surgery and increasing the rate of subjects to whom panretinal photocoagulation could be applied in the early period, although there was no impact on final visual acuity.
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Cengiz
authors.initials: C
authors.lastname: Alagöz
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yıldırım
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Kocamaz
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Ökkeş
authors.initials: Ö
authors.lastname: Baz
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Uğur
authors.initials: U
authors.lastname: Çiçek
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Burcu
authors.initials: B
authors.lastname: Çelik
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Halil İbrahim
authors.initials: Hİ
authors.lastname: Demirkale
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Ahmet Taylan
authors.initials: AT
authors.lastname: Yazıcı
authors.affiliation: Beyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
authors.forename: Muhittin
authors.initials: M
authors.lastname: Taşkapılı
keywords: Proliferative diabetic retinopathy; intravitreal bevacizumab; vitreous hemorrhage