title: Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study.
abstract: This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.
authors.affiliation: Institute of Health Informatics, University College London, London, UK. c.warren-gash@ucl.ac.uk.|The Farr Institute of Health Informatics Research, 222 Euston Road, London, NW1 2DA, UK. c.warren-gash@ucl.ac.uk.
authors.forename: Charlotte
authors.identifier: http://orcid.org/0000-0003-4524-3180
authors.initials: C
authors.lastname: Warren-Gash
authors.affiliation: Institute of Liver Studies, King's College Hospital, London, UK.
authors.forename: Kate
authors.initials: K
authors.lastname: Childs
authors.affiliation: Research Department of Infection and Population Health, University College London, London, UK.
authors.forename: Alicia
authors.initials: A
authors.lastname: Thornton
authors.affiliation: Department of Infectious Diseases, Royal Free London NHS Foundation Trust, London, UK.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Bhagani
authors.affiliation: Institute for Liver and Digestive Health, Division of Medicine, University College London, London, UK.|Hepatology Unit, Department of Experimental and Clinical Medicine, University of Catania, Catania, Italy.
authors.forename: Shirin
authors.initials: S
authors.lastname: Demma
authors.affiliation: Institute for Liver and Digestive Health, Division of Medicine, University College London, London, UK.
authors.forename: Ankur
authors.initials: A
authors.lastname: Srivastava
authors.affiliation: Regional Infectious Diseases Unit, Western General Hospital, Edinburgh, UK.
authors.forename: Clifford
authors.initials: C
authors.lastname: Leen
authors.affiliation: Institute of Liver Studies, King's College Hospital, London, UK.
authors.forename: Kosh
authors.initials: K
authors.lastname: Agarwal
authors.affiliation: Research Department of Infection and Population Health, University College London, London, UK.|Department of Infectious Diseases, Royal Free London NHS Foundation Trust, London, UK.
authors.forename: Alison J
authors.initials: AJ
authors.lastname: Rodger
authors.affiliation: Research Department of Infection and Population Health, University College London, London, UK.
authors.forename: Caroline A
authors.initials: CA
authors.lastname: Sabin
mesh_terms: D000328:Adult; D060085:Coinfection / Q000150:complications*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D019694:Hepatitis B, Chronic / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000453:epidemiology* / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D006113:United Kingdom
keywords: Cirrhosis; Co-infection; HIV; Hepatitis B; Hepatitis C; Liver transplantation