title: The role of dexamethasone in decreasing early recurrence of acute intussusception in children: A retrospective study.
abstract: BACKGROUND
  Early recurrent intussusception (RI) is a concern after a successful pneumatic reduction. Steroids have been suggested as a treatment that decreases early RI. The purpose of this study was to examine the role of dexamethasone in decreasing early RI.
  
  
  METHODS
  A retrospective review of 174 pediatric patients that underwent successful pneumatic reduction was conducted. Two groups were identified: group 1 that received intravenous dexamethasone (0.5mg/kg/dose) on diagnosis or immediately after the reduction maneuver, and group 2 that were not given dexamethasone.
  
  
  RESULTS
  There were 113 boys and 61 girls ranging in age from 2 to 36months. There were no statistical differences between the groups except for younger age in the dexamethasone group (P=0.03). There was no significant difference (p=0.08) in the rate of early RI between the non-steroid group (5.4%, 4/74) and the steroid group 14% (14/100). Mean admission length was 30h. The majority of RIs occurred in the first 8h of admission.
  
  
  CONCLUSIONS
  We found that premedication of children with idiopathic intussusception with dexamethasone did not decrease early RI.
  
  
  METHODS
  Level III retrospective comparative study.
authors.affiliation: Pediatric Division, Assaf Harofeh Medical Centre, Zerifin 70300, Israel, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: yigale@asaf.health.gov.il.
authors.forename: Yigal
authors.initials: Y
authors.lastname: Efrati
authors.affiliation: Pediatric Division, Assaf Harofeh Medical Centre, Zerifin 70300, Israel, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: klin2@netvision.net.il.
authors.forename: Baruch
authors.initials: B
authors.lastname: Klin
authors.affiliation: Pediatric Division, Assaf Harofeh Medical Centre, Zerifin 70300, Israel, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: erank@asaf.health.gov.il.
authors.forename: Eran
authors.initials: E
authors.lastname: Kozer
authors.affiliation: Pediatric Division, Assaf Harofeh Medical Centre, Zerifin 70300, Israel, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address: abukishki@gmail.com.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Abu-Kishk
mesh_terms: D002675:Child, Preschool; D003907:Dexamethasone / Q000008:administration & dosage*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007443:Intussusception / Q000188:drug therapy* / Q000601:surgery*; D008297:Male; D008467:Meckel Diverticulum / Q000601:surgery; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone
keywords: Dexamethasone; Infants; Intussusception; Recurrence