title: Attributable risk of ambient PM10on daily mortality and years of life lost in Chengdu, China.
abstract: Attributable risk is an important indicator for planning and evaluating public health interventions. However, most current measures of the attributable risk of air pollutants have not considered temporal relationships between exposure and risk. More importantly, limited information is available regarding the attributable risk due to ambient air pollutants in basin regions like the Sichuan Basin, China. To quantify the association between PM10and deaths in the Basin region, we used a measure proposed recently within the framework of the distributed lag non-linear model to estimate the attributable risk in Chengdu, China. Meanwhile, we examined the association between PM10and years of life lost (YLL). Our analysis showed that population-attributable fractions for non-accidental, respiratory, and cardiovascular mortality were 0.569% (95% CI: -3.474%, 4.374%), 0.695% (95% CI: -5.260%, 6.457%), and 0.631% (95% CI: -6.973%, 7.390%), respectively. On average, a 1μg/m3increase in PM10was associated with cumulative increases of 0.26893, 0.30437, and 0.21924 YLL for non-accidental, respiratory, and cardiovascular mortality, respectively, referring to 20μg/m3. In addition, we found an inverse U-shaped pattern for the cumulative risk with 350μg/m3as the reverse point. With a 1μg/m3increase in PM10, YLL changed more significantly than mortality. Moreover, PM10demonstrated remarkable effects on YLL among men and the elderly.
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Chen
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Zibing
authors.initials: Z
authors.lastname: Deng
authors.affiliation: Sichuan Centre for Disease Control and Prevention, Chengdu 610041, Sichuan, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Deng
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Zhijiao
authors.initials: Z
authors.lastname: Qiao
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Lan
authors.affiliation: School of Public Health, Kunming Medical University, Kunming, 650500, Yunnan, China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Meng
authors.affiliation: Sichuan Environmental Monitoring Centre, Chengdu 610041, Sichuan, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Luo
authors.affiliation: Sichuan Environmental Monitoring Centre, Chengdu 610041, Sichuan, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Sichuan Centre for Disease Control and Prevention, Chengdu 610041, Sichuan, China.
authors.forename: Kui
authors.initials: K
authors.lastname: Ji
authors.affiliation: Institute of New Energy and Low-Carbon Technology, Sichuan University, Chengdu, Sichuan, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Qiao
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Fan
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Meixia
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Cui
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address: zhaoxing731@gmail.com.
authors.forename: Xing
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address: lixiaosong1101@126.com.
authors.forename: Xiaosong
authors.initials: X
authors.lastname: Li
mesh_terms: D000397:Air Pollution / Q000009:adverse effects*; D002681:China; D006801:Humans; D009026:Mortality; D052638:Particulate Matter / Q000009:adverse effects; D011634:Public Health; D012307:Risk Factors
chemical_list: D052638:Particulate Matter
keywords: China; Disease burden; Mortality; PM(10); YLL