title: Favourably effective formulation of sodium iodide and salicylic acid plus professional hygiene in patients affected by desquamative gingivitis.
abstract: The aim of this prospective pilot study was to evaluate the efficiency of an oral hygiene protocol, in combination with a solution of sodium iodide associated to salicylic acid (SISA), in patients affected by desquamative gingivitis (DG). Twenty patients not totally responding to conventional topical therapies, were selected. They received oral hygiene instructions with non-surgical periodontal therapy in a 21-day cohort study (during 3 weekly appointments). The SISA was used at the end of each session, with an impregnated gauze (with 5 ml of the solution) applied for 15 minutes for the upper jaw, and for a further 15 minutes with a new gauze for the lower. Evaluated clinical outcome variables included the full mouth plaque (FMPS) and bleeding (FMBS) scores, probing depth, patient related outcome and clinical gingival signs. Two months after concluding the planned protocol, a statistically significant reduction was observed for FMPS (P=0.032), FMBS (P=0.038), reported pain (P=0.000) and gingival clinical improvement (P=0.005). Topical application of SISA and professional oral hygiene procedures are connected with improvement of gum status, and decrease of related pain in subjects affected by severe DG.
authors.affiliation: Department of Surgical Sciences, Cir-Dental School, University of Turin, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Carcieri
authors.affiliation: Department of Surgical Sciences, Cir-Dental School, University of Turin, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Broccoletti
authors.affiliation: Department of Surgical Sciences, Cir-Dental School, University of Turin, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Giacometti
authors.affiliation: Department of Surgical Sciences, Cir-Dental School, University of Turin, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Gambino
authors.affiliation: Department of Surgical Sciences, Cir-Dental School, University of Turin, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Conrotto
authors.affiliation: Department of Surgical Sciences, Cir-Dental School, University of Turin, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Cabras
authors.affiliation: Department of Surgical Sciences, Cir-Dental School, University of Turin, Italy.
authors.forename: P G
authors.initials: PG
authors.lastname: Arduino
mesh_terms: D000287:Administration, Topical; D003729:Dental Care / Q000379:methods*; D003774:Dental Plaque Index; D005260:Female; D005891:Gingivitis / Q000628:therapy*; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009910:Oral Hygiene / Q000379:methods*; D010865:Pilot Projects; D011446:Prospective Studies; D020156:Salicylic Acid / Q000008:administration & dosage*; D012974:Sodium Iodide / Q000008:administration & dosage*
chemical_list: D007641:Keratolytic Agents; D012974:Sodium Iodide; D020156:Salicylic Acid