title: The metabolic sensor AKIN10 modulates the Arabidopsis circadian clock in a light-dependent manner.
abstract: Plants generate rhythmic metabolism during the repetitive day/night cycle. The circadian clock produces internal biological rhythms to synchronize numerous metabolic processes such that they occur at the required time of day. Metabolism conversely influences clock function by controlling circadian period and phase and the expression of core-clock genes. Here, we show that AKIN10, a catalytic subunit of the evolutionarily conserved key energy sensor sucrose non-fermenting 1 (Snf1)-related kinase 1 (SnRK1) complex, plays an important role in the circadian clock. Elevated AKIN10 expression led to delayed peak expression of the circadian clock evening-element GIGANTEA (GI) under diurnal conditions. Moreover, it lengthened clock period specifically under light conditions. Genetic analysis showed that the clock regulator TIME FOR COFFEE (TIC) is required for this effect of AKIN10. Taken together, we propose that AKIN10 conditionally works in a circadian clock input pathway to the circadian oscillator.
authors.affiliation: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, 50829, Germany.
authors.forename: Jieun
authors.initials: J
authors.lastname: Shin
authors.affiliation: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, 50829, Germany.|Colegio de Postgraduados campus Campeche, Campeche, 24750, Mexico.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Sánchez-Villarreal
authors.affiliation: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, 50829, Germany.|Department of Biology, University of York, York, YO10 5DD, UK.
authors.forename: Amanda M
authors.initials: AM
authors.lastname: Davis
authors.affiliation: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, 50829, Germany.
authors.forename: Shen-Xiu
authors.initials: SX
authors.lastname: Du
authors.affiliation: Zentrum für Molekularbiologie der Pflanzen, Universität Tübingen, Tübingen, 72076, Germany.
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Berendzen
authors.affiliation: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, 50829, Germany.
authors.forename: Csaba
authors.initials: C
authors.lastname: Koncz
authors.affiliation: College of Life Sciences, Shandong University, Jinan, 250100, China.
authors.forename: Zhaojun
authors.initials: Z
authors.lastname: Ding
authors.affiliation: College of Life Sciences, Shandong University, Jinan, 250100, China.
authors.forename: Cuiling
authors.initials: C
authors.lastname: Li
authors.affiliation: Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, 50829, Germany.|Department of Biology, University of York, York, YO10 5DD, UK.
authors.forename: Seth J
authors.identifier: http://orcid.org/0000-0001-5928-9046
authors.initials: SJ
authors.lastname: Davis
mesh_terms: D017360:Arabidopsis / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D057906:Circadian Clocks / Q000502:physiology*; D018506:Gene Expression Regulation, Plant; D008027:Light; D009154:Mutation; D009687:Nuclear Proteins / Q000235:genetics; D030821:Plants, Genetically Modified; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D009687:Nuclear Proteins; D017346:Protein Serine-Threonine Kinases; C523534:TIC protein, Arabidopsis; C531469:At3g01090 protein, Arabidopsis
keywords: light signalling; metabolism