title: Spinal cord infarction at the level of ossification of the posterior longitudinal ligament.
abstract: BACKGROUND
  We report a case of acute tetraplegia, without any trauma or symptoms prior to onset, who presented with ossification of the posterior longitudinal ligament (OPLL) in the cervical spine with concomitant spinal cord infarction.
  
  
  METHODS
  A 64-year-old man with a number of risk factors for vascular disease was admitted to our hospital with progressive motor weakness in the bilateral upper and lower extremities. He had initially felt numbness in his left upper extremity and had no previous neurological symptoms or trauma. The night after the initial symptoms, he developed spastic tetraplegia requiring respiratory support. Computed tomography images of the cervical spine demonstrated the segmental type of OPLL. Spinal cord compression and signal intensity changes were identified at the level of C3/4 on magnetic resonance imaging (MRI). He underwent emergency surgery consisting of posterior decompression with laminoplasty of C3-6. Despite the surgery, the patient's tetraplegia did not improve and he continued to require respirator support. There was still no improvement in his neurological status at 10 days postoperatively, and MRI demonstrated evidence of marked spinal cord infarction.
  
  
  CONCLUSIONS
  Mechanical compression of spinal arteries by OPLL and pre-existing vascular compromise had a role in the pathogenesis of spinal cord infarction. Chronic spinal compression may be characterized by 3 important factors, namely an uncommonly devastating clinical course, vascular risk factors and persistent findings on MRI, and these might lead to early diagnosis of spinal cord infarction.
authors.affiliation: Department of Orthopedic Surgery, Faculty of Medicine, Tottori University , Tottori, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tanida
authors.affiliation: Department of Orthopedic Surgery, Faculty of Medicine, Tottori University , Tottori, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kamimura
authors.affiliation: Department of Orthopedic Surgery, Faculty of Medicine, Tottori University , Tottori, Japan.
authors.forename: Shinji
authors.initials: S
authors.lastname: Tanishima
authors.affiliation: Department of Orthopedic Surgery, Faculty of Medicine, Tottori University , Tottori, Japan.
authors.forename: Tokumitsu
authors.initials: T
authors.lastname: Mihara
authors.affiliation: Department of Orthopedic Surgery, Faculty of Medicine, Tottori University , Tottori, Japan.
authors.forename: Chikako
authors.initials: C
authors.lastname: Takeda
authors.affiliation: Department of Orthopedic Surgery, Faculty of Medicine, Tottori University , Tottori, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Nagashima
keywords: Spinal cord diseases; Stroke