title: Longitudinal Cohort Study on the Incidence of Primary Open-Angle Glaucoma in Bai Chinese.
abstract: OBJECTIVE
  The prevalence of primary open-angle glaucoma (POAG) in China has been reported previously, and was lower than that in white and black populations. However, the incidence of POAG in China has not been reported. Therefore, a longitudinal study was conducted to determine the 5-year cumulative incidence and predictors of POAG in China.
  
  
  METHODS
  Population-based cohort study.
  
  
  METHODS
  A total of 1520 participants (71.3% of the subjects in the baseline survey) of Bai ethnicity were examined and followed for 5 years. Glaucoma was defined based on the International Society of Geographical and Epidemiological Ophthalmology Classification criteria. Multivariable logistic regression models were fitted to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs).
  
  
  RESULTS
  A total of 19 new cases of POAG were detected. The 5-year cumulative incidence of POAG was 1.3% (95% CI, 0.7-1.9). In multivariate analyses, incident POAG was associated with baseline variables including increased age (OR, 4.3; 95% CI, 1.4-13.8; P = .02; 70 years or older vs 50-59 years), elevated IOP (OR, 3.5; 95% CI, 2.0-5.9; P < .001; per 10 mm Hg increase), lower education level (OR, 0.3; 95% CI, 0.1-0.8; P = .02; post-primary education vs no formal education), and the presence of myopia (OR, 3.4; 95% CI, 1.3-8.6; P < .01).
  
  
  CONCLUSIONS
  The average annual incidence of POAG in Bai Chinese was lower than that in populations of African descent and white race. The results are important to elucidate the racial/ethnic difference in POAG incidence and for the clinical management and health resource allocation in China.
authors.affiliation: Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Medical College of Soochow University, Suzhou, China.
authors.forename: Chen-Wei
authors.initials: CW
authors.lastname: Pan
authors.affiliation: Department of Ophthalmology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
authors.forename: Wen-Yan
authors.initials: WY
authors.lastname: Yang
authors.affiliation: New York Eye and Ear Infirmary at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, New York.
authors.forename: Dan-Ning
authors.initials: DN
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
authors.forename: Jian-Gang
authors.initials: JG
authors.lastname: Xu
authors.affiliation: Department of Ophthalmology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Niu
authors.affiliation: Department of Ophthalmology, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
authors.forename: Yuan-Sheng
authors.initials: YS
authors.lastname: Yuan
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
authors.forename: Min-Bin
authors.initials: MB
authors.lastname: Yu
authors.affiliation: Department of Ophthalmology, the First Affiliated Hospital of Kunming Medical University, Kunming, China. Electronic address: zhoculist@163.com.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D016001:Confidence Intervals; D005006:Ethnicity; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000208:ethnology*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods*; D015995:Prevalence; D012189:Retrospective Studies; D013997:Time Factors