title: Management of sickle cell disease in patients undergoing cardiac surgery.
abstract: Sickle cell disease is a life-limiting inherited hemoglobinopathy that poses inherent risk for surgical complications following cardiac operations. In this review, we discuss preoperative considerations, intraoperative decision-making, and postoperative strategies to optimize the care of a patient with sickle cell disease undergoing cardiac surgery.
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Todd C
authors.initials: TC
authors.lastname: Crawford
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Michael V
authors.initials: MV
authors.lastname: Carter
authors.affiliation: Division of Hematology, Department of Medicine, Greater Baltimore Medical Center, Baltimore, Maryland.
authors.forename: Rina K
authors.initials: RK
authors.lastname: Patel
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Suarez-Pierre
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Sophie Z
authors.initials: SZ
authors.lastname: Lin
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Jonathan Trent
authors.initials: JT
authors.lastname: Magruder
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Joshua C
authors.initials: JC
authors.lastname: Grimm
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Duke E
authors.initials: DE
authors.lastname: Cameron
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: William A
authors.initials: WA
authors.lastname: Baumgartner
authors.affiliation: Division of Cardiac Surgery Baltimore, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Mandal
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications / Q000628:therapy*; D001281:Atrial Fibrillation / Q000150:complications / Q000601:surgery; D001803:Blood Transfusion / Q000379:methods*; D006348:Cardiac Surgical Procedures; D019468:Disease Management; D006333:Heart Failure / Q000150:complications* / Q000601:surgery; D006801:Humans; D008297:Male; D011300:Preoperative Care / Q000379:methods*