title: The Efficacy of Q-Switched ND:YAG 1064 nm Laser in Recalcitrant Macular Amyloidosis: A Case Report.
abstract: Macular amyloidosis typically presents as small, dusky-brown or greyish pigmented macules, the result of altered keratin deposition. Treatment of these hyperpigmented regions with topical and systemic therapies remains challenging, however Q-Switched neodymi- um-doped yttrium aluminum garnet (ND:YAG) laser has proven to be an effective treatment modality to reduce hyperpigmentation. In this case report we investigated the ef cacy of Q-Switched Nd:YAG laser treatment on a 34-year old woman with recalcitrant macular amyloidosis who failed to respond to over-the-counter bleaching creams. The patient was treated with 7 treatment sessions of Q- Switched Nd:YAG laser at one month intervals. According to our photographic analysis and patient self-assessment, the patient ap- peared to improve with each treatment session. Post-recurrence of the lesion after reaction to Triluma ( uocoinolone actetonide 0.01%, hydroquinone 4%, tretinoin 0.05%), the patient has been continuing to respond well to a second round of treatment with Q-switched Nd:YAG laser at 1064 nm. <em>J Drugs Dermatol. 2016;15(11):1456-1458.</em>.
authors.forename: Nevil
authors.initials: N
authors.lastname: Khurana
authors.forename: Christine
authors.initials: C
authors.lastname: Urman
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000150:complications / Q000175:diagnosis* / Q000532:radiotherapy*; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D016896:Treatment Outcome