title: Selenium rescues orbital fibroblasts from cell death induced by hydrogen peroxide: another molecular basis for the effects of selenium in graves' orbitopathy.
authors.affiliation: Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Giovanna
authors.initials: G
authors.lastname: Rotondo Dottore
authors.affiliation: Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Chiarini
authors.affiliation: Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: De Gregorio
authors.affiliation: Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Marenza
authors.initials: M
authors.lastname: Leo
authors.affiliation: Department of Surgical, Medical and Molecular Pathology, Ophthalmopathy Unit I, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Giamberto
authors.initials: G
authors.lastname: Casini
authors.affiliation: Department of Surgical, Medical and Molecular Pathology, Ophthalmopathy Unit I, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Cestari
authors.affiliation: Department of Surgical, Medical and Molecular Pathology, ENT Unit I, University of Pisa and University Hospital of Pisa, Italy, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Sellari-Franceschini
authors.affiliation: Department of Surgical, Medical and Molecular Pathology, Ophthalmopathy Unit I, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Nardi
authors.affiliation: Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Vitti
authors.affiliation: Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Marcocci
authors.affiliation: Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Via Paradisa 2, Pisa, 56124, Italy. michele.marino@med.unipi.it.
authors.forename: Michele
authors.identifier: 0000-0003-0365-116X
authors.initials: M
authors.lastname: Marinò
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects / Q000473:pathology; D000368:Aged; D016923:Cell Death / Q000187:drug effects / Q000235:genetics; D002478:Cells, Cultured; D019610:Cytoprotection / Q000187:drug effects*; D005260:Female; D005347:Fibroblasts / Q000187:drug effects* / Q000473:pathology; D049970:Graves Ophthalmopathy / Q000188:drug therapy* / Q000473:pathology / Q000517:prevention & control; D006801:Humans; D006861:Hydrogen Peroxide / Q000633:toxicity*; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000187:drug effects* / Q000473:pathology; D061251:Primary Cell Culture; D012643:Selenium / Q000494:pharmacology* / Q000627:therapeutic use; D015398:Signal Transduction / Q000187:drug effects / Q000235:genetics
chemical_list: D006861:Hydrogen Peroxide; D012643:Selenium