title: Sphincter of Oddi Dysfunction: A Perplexing Presentation.
abstract: Sphincter of Oddi dysfunction is caused by stenosis or dyskinesia of the sphincter of Oddi, leading to blockage of bile drainage from the common bile duct. We present the case of a 16-year-old female with chronic abdominal pain who underwent laparoscopic cholecystectomy for cholelithiasis but continued to experience abdominal pain, nausea, and vomiting along with persistently elevated ALT and AST levels. Postoperative abdominal ultrasound was nondiagnostic. Esophagogastroduodenoscopy showed mild reflux esophagitis and mild chronicHelicobacter pylori-negative gastritis. Omeprazole was started, but it did not decrease the frequency and severity of the abdominal symptoms. Magnetic resonance cholangiopancreatography did not reveal any pathology. Endoscopic retrograde cholangiopancreatography with manometry confirmed an elevated biliary sphincter pressure. Biliary sphincterotomy was performed, and the symptoms improved.
authors.affiliation: Division of Pediatric Gastroenterology, Hepatology and Nutrition, SUNY Upstate Medical University, Golisano Children's Hospital, Syracuse, NY, USA.
authors.forename: Sana Ahmad
authors.initials: SA
authors.lastname: Din
authors.affiliation: Division of Pediatric Gastroenterology, Hepatology and Nutrition, SUNY Upstate Medical University, Golisano Children's Hospital, Syracuse, NY, USA.
authors.forename: Iman
authors.initials: I
authors.lastname: Naimi
authors.affiliation: Division of Pediatric Gastroenterology, Hepatology and Nutrition, SUNY Upstate Medical University, Golisano Children's Hospital, Syracuse, NY, USA.
authors.forename: Mirza
authors.initials: M
authors.lastname: Beg
keywords: Abdominal pain; Cholecystectomy; Endoscopic retrograde cholangiopancreatography; Pediatrics; Sphincter of Oddi