title: Prevalence profile of odontogenic cysts and tumors on Brazilian sample after the reclassification of odontogenic keratocyst.
abstract: OBJECTIVE
  The aim of this study was to evaluate the impact of the reclassification of odontogenic keratocyst (OKC) as a tumor on the prevalence profile of odontogenic cysts (OCs) and odontogenic tumors (OTs).
  
  
  METHODS
  Two referral Oral and Maxillofacial Pathology services in Brazil were evaluated. All cases diagnosed as OCs or OTs were selected and classified according to the 1992 WHO-classification (cases before 2005 WHO classification of tumors excluding OKC) and the 2005 WHO classification of tumors, going forward including cases of odontogenic keratocyst tumor (KCOT). The frequency and prevalence of OCs and OTs were compared before and after the reclassification.
  
  
  RESULTS
  Among 27,854 oral biopsies, 4920 (17.66%) were OCs and 992 (3.56%) were OTs. The prevalence of OTs before 2005 WHO classification of tumors was 2.04%, while the prevalence after 2005 WHO classification was 11.51% (p < 0.0001). Before 2006, the most frequent tumor diagnosed was odontoma with 194 cases (39.67%), and after 2005 WHO classification of tumors the KCOT was the most frequent with 207 cases (41.07%).
  
  
  CONCLUSIONS
  The increase in the prevalence of OTs after 2005 WHO is related to the improvement of pathology services and to the inclusion of KCOT in the OTs group.
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Department of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, Brazil; Department of Dentistry, Centro Universitário Newton Paiva, Belo Horizonte, Brazil. Electronic address: filipejaeger@gmail.com.
authors.forename: Filipe
authors.initials: F
authors.lastname: Jaeger
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Mariana Saturnino
authors.initials: MS
authors.lastname: de Noronha
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Maiza Luiza Vieira
authors.initials: ML
authors.lastname: Silva
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Márcio Bruno Figueiredo
authors.initials: MB
authors.lastname: Amaral
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Department of Dentistry, Universidade Vale do Rio Verde - UninCor, Belo Horizonte, Brazil.
authors.forename: Soraya de Mattos Carmago
authors.initials: SM
authors.lastname: Grossmann
authors.affiliation: Department of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Martinho Campolina Rebello
authors.initials: MC
authors.lastname: Horta
authors.affiliation: Department of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Paulo Eduardo Alencar
authors.initials: PE
authors.lastname: de Souza
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Maria Cássia Ferreira
authors.initials: MC
authors.lastname: de Aguiar
authors.affiliation: Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Ricardo Alves
authors.initials: RA
authors.lastname: Mesquita
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000145:classification / Q000453:epidemiology*; D007573:Jaw Neoplasms / Q000145:classification / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009807:Odontogenic Cysts / Q000145:classification / Q000453:epidemiology*; D009808:Odontogenic Tumors / Q000145:classification / Q000453:epidemiology*; D015995:Prevalence; D012737:Sex Factors; D055815:Young Adult
keywords: Keratocyst odontogenic tumor; Odontogenic cysts; Odontogenic keratocyst; Odontogenic tumors