title: Evaluation of Herpes Simplex Virus Type 2 Serological Tests for Use With Dried Blood Spots in Kenya.
abstract: We evaluated 2 assays to detect antibodies to herpes simplex virus type 2 in dried blood spots prepared from blood specimens submitted to a reference laboratory in Kenya. Dried blood spots did not perform well with the Kalon herpes simplex virus type 2 assay. Focus HerpeSelect 2 was 98.8% sensitive and 98.9% specific with dried blood spots.
authors.affiliation: From the *Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; †National HIV Reference Laboratory, Ministry of Health, Nairobi, Kenya; ‡Pacific Institute for Research and Evaluation; and §Department of Maternal and Child Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
authors.forename: Marcia M
authors.initials: MM
authors.lastname: Hobbs
authors.forename: Sophie W
authors.initials: SW
authors.lastname: Mwanyumba
authors.forename: Winnie K
authors.initials: WK
authors.lastname: Luseno
authors.forename: Shane
authors.initials: S
authors.lastname: Hartman
authors.forename: Carolyn T
authors.initials: CT
authors.lastname: Halpern
authors.forename: Denise D
authors.initials: DD
authors.lastname: Hallfors
authors.forename: Hyunsan
authors.initials: H
authors.lastname: Cho
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D006561:Herpes Simplex / Q000175:diagnosis* / Q000821:virology; D018258:Herpesvirus 2, Human / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012698:Serologic Tests
chemical_list: D000914:Antibodies, Viral