title: PDE3 inhibition with enoximone as first-line therapy for severe persistent pulmonary hypertension of the newborn during neonatal transport: a case report.
abstract: Severe Persistent pulmonary hypertension of the newborn (PPHN) can be effectively treated with a PDE3 inhibitor as first-line treatment during neonatal transport when iNO is not readily available. Starting iNO as soon as possible is strongly advised because of the complementary actions of both therapeutics.
authors.affiliation: Emma Children's Hospital Academic Medical Center Meibergdreef 15 1105AZ Amsterdam Netherlands.
authors.forename: Robin
authors.initials: R
authors.lastname: van der Lee
authors.affiliation: Wilhelmina Childrens's Hospital University Medical Center Lundlaan 6 3584EA Utrecht Netherlands.
authors.forename: Barbara
authors.initials: B
authors.lastname: Peels
authors.affiliation: Wilhelmina Childrens's Hospital University Medical Center Lundlaan 6 3584EA Utrecht Netherlands.
authors.forename: Corine
authors.initials: C
authors.lastname: Koopman-Esseboom
keywords: Enoximone; nitric oxide; neonatal transport; persistent pulmonary hypertension of the newborn; phosphodiesterase inhibitor