title: Effect of Prepublication Results on Trends in Prescribing of Antihypertensive Medication: Impact of the ALTITUDE (Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Disease Endpoints) Trial on Aliskiren Prescribing.
authors.affiliation: From the Institute for Clinical Evaluative Sciences (S.S.O., P.C.A., J.V.T., D.S.L.), the Institute for Medical Sciences, University of Toronto (S.S.O., D.S.L.), Sunnybrook Health Sciences Centre (J.V.T.), and the Peter Munk Cardiac Centre and the Joint Department of Medical Imaging, University Health Network, University of Toronto, Canada (D.S.L.).
authors.forename: Sahar S
authors.initials: SS
authors.lastname: Othman
authors.affiliation: From the Institute for Clinical Evaluative Sciences (S.S.O., P.C.A., J.V.T., D.S.L.), the Institute for Medical Sciences, University of Toronto (S.S.O., D.S.L.), Sunnybrook Health Sciences Centre (J.V.T.), and the Peter Munk Cardiac Centre and the Joint Department of Medical Imaging, University Health Network, University of Toronto, Canada (D.S.L.).
authors.forename: Peter C
authors.initials: PC
authors.lastname: Austin
authors.affiliation: From the Institute for Clinical Evaluative Sciences (S.S.O., P.C.A., J.V.T., D.S.L.), the Institute for Medical Sciences, University of Toronto (S.S.O., D.S.L.), Sunnybrook Health Sciences Centre (J.V.T.), and the Peter Munk Cardiac Centre and the Joint Department of Medical Imaging, University Health Network, University of Toronto, Canada (D.S.L.).
authors.forename: Jack V
authors.initials: JV
authors.lastname: Tu
authors.affiliation: From the Institute for Clinical Evaluative Sciences (S.S.O., P.C.A., J.V.T., D.S.L.), the Institute for Medical Sciences, University of Toronto (S.S.O., D.S.L.), Sunnybrook Health Sciences Centre (J.V.T.), and the Peter Munk Cardiac Centre and the Joint Department of Medical Imaging, University Health Network, University of Toronto, Canada (D.S.L.). dlee@ices.on.ca.
authors.forename: Douglas S
authors.initials: DS
authors.lastname: Lee
mesh_terms: D000368:Aged; D000577:Amides / Q000494:pharmacology*; D000959:Antihypertensive Agents; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D005260:Female; D005650:Fumarates / Q000494:pharmacology*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D009864:Ontario; D012189:Retrospective Studies
chemical_list: D000577:Amides; D000959:Antihypertensive Agents; D005650:Fumarates; C446481:aliskiren
keywords: angiotensin receptor antagonist; angiotensin-converting enzyme inhibitor; blood pressure; drug therapy; health policy; hypertension; hypotension