title: Disseminated eruptive granuloma annulare induced by levetiracetam.
abstract: Granuloma annulare (GA) is a benign, granulomatous cutaneous disease without clear etiology. Disseminated and drug induced granuloma annulare is a rare presentation. We present a 47-year-old woman with diffuse circular erythematous eruptions following treatment with levetiracetam. Her clinical and histopathological findings were compatible with the diagnosis of granuloma annulare. To the best of our knowledge, there is no previous report of this skin disease as a result of levetiracetam use. We report this case to highlight this antiepileptic drug as a possible etiologic agent in disseminated granuloma annulare.
authors.affiliation: a Dermatology, Abant Izzet Baysal University Medical Faculty , Bolu , Turkey.
authors.forename: Betul
authors.initials: B
authors.lastname: Sereflican
authors.affiliation: a Dermatology, Abant Izzet Baysal University Medical Faculty , Bolu , Turkey.
authors.forename: Tekden
authors.initials: T
authors.lastname: Karapinar
authors.affiliation: b Pathology, Abant Izzet Baysal Universitesi , Bolu , Turkey , and.
authors.forename: Selma Erdogan
authors.initials: SE
authors.lastname: Duzcu
authors.affiliation: c Neurology, Abant Izzet Baysal Universitesi , Bolu , Turkey.
authors.forename: Şule Aydin
authors.initials: ŞA
authors.lastname: Turkoglu
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D016460:Granuloma Annulare / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D000077287:Levetiracetam; D008875:Middle Aged; D010889:Piracetam / Q000009:adverse effects / Q000031:analogs & derivatives*; D012867:Skin / Q000187:drug effects / Q000473:pathology
chemical_list: D000927:Anticonvulsants; D000077287:Levetiracetam; D010889:Piracetam
keywords: Disseminated; drug; eruptive; granuloma annulare; levetiracetam