title: Hemoglobin Kansas as a Rare Cause of Cyanosis: A Case Report and Review of the Literature.
abstract: Hemoglobin (Hb) Kansas is an inherited Hb variant with a low oxygen affinity that is associated with low oxygen saturation on pulse oximetry (SpO2). It leads to asymptomatic cyanosis. Patients with Hb Kansas do not require any specific treatment and the prognosis is good. In patients with unexplained cyanosis, we should thus consider Hb variants, including Hb Kansas and avoid unnecessary investigations and managements. We herein report the case of 65-year-old woman with Hb Kansas and review five other cases (three lineages) that have been reported in Japan.
authors.affiliation: Department of Internal Medicine IV, Teikyo University School of Medicine, University Hospital, Mizonokuchi, Japan.
authors.forename: Yoshikuni
authors.initials: Y
authors.lastname: Nagayama
authors.forename: Minoru
authors.initials: M
authors.lastname: Yoshida
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kohyama
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Matsui
mesh_terms: D000368:Aged; D003490:Cyanosis / Q000209:etiology*; D003937:Diagnosis, Differential; D004586:Electrophoresis; D005260:Female; D006453:Hemoglobinopathies / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D010092:Oximetry
chemical_list: D006455:Hemoglobins, Abnormal; C017360:hemoglobin Kansas