title: Effective cerebrovascular thrombectomy requires well-organized structures : Real world experiences of a regional stroke network between 2012-2015.
abstract: BACKGROUND
  The objective of this study was to analyse the Neurothrombectomy Network registry of the Neuromed Campus (NMC) of the Kepler University Hospital in Linz (Austria). The data were compared to the results of recently published thrombectomy trials (MR CLEAN, ESCAPE, EXTEND-IA, SWIFT-PRIME, REVASCAT and THRACE).
  
  
  METHODS
  We retrospectively studied 246 patients with acute ischemic stroke who underwent thrombectomy between January 2012 and December 2015 at the NMC in Upper Austria. The main outcome measures were modified Rankin scale (mRS) score 0-2 at 90 days, all-cause mortality and stroke or thrombectomy-related mortality at discharge, as well as 90 days postdischarge.
  
  
  RESULTS
  The median age was 70.4 years (IQR 59.9-76.9) and the median NIHSS at admission 16 (IQR 13-20). The thrombolysis in cerebral infarction (TICI) scale 2b-3 recanalization was achieved in 87.4%, 11.0% of the patients died in hospital and an additional 6.1% within 90 days after discharge. After 90 days, 56.5% had a mRS score 0-2.
  
  
  CONCLUSIONS
  These data suggest that the positive results of thrombectomy reported in several randomized controlled studies can be achieved in routine clinical practice; therefore, the setting of an organized, regional stroke network proved an effective and appropriate method for delivering regional thrombectomy stroke treatment.
authors.affiliation: Department of Neurology, Neuromed Campus - Kepler University Hospital, Wagner Jauregg Weg 15, 4020, Linz, Austria.
authors.forename: Maria Sophie
authors.initials: MS
authors.lastname: Stockinger
authors.affiliation: Department of Radiology, Neuromed Campus - Kepler University Hospital, Linz, Austria.
authors.forename: Johannes
authors.initials: J
authors.lastname: Trenkler
authors.affiliation: Department of Neurology, Neuromed Campus - Kepler University Hospital, Wagner Jauregg Weg 15, 4020, Linz, Austria.
authors.forename: Tim
authors.initials: T
authors.lastname: von Oertzen
authors.affiliation: Department of Radiology, Neuromed Campus - Kepler University Hospital, Linz, Austria.
authors.forename: Karin
authors.initials: K
authors.lastname: Nussbaumer
authors.affiliation: Department of Radiology, Neuromed Campus - Kepler University Hospital, Linz, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Sonnberger
authors.affiliation: ASOKLIF, Department of Applied Systems Research and Statistics, Kepler University, Linz, Austria.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Schimetta
authors.affiliation: Department of Neurology, St. George's University Hospitals NHS Foundation Trust, London, UK.
authors.forename: Anthony C
authors.initials: AC
authors.lastname: Pereira
authors.affiliation: Department of Neurology, Neuromed Campus - Kepler University Hospital, Wagner Jauregg Weg 15, 4020, Linz, Austria.
authors.forename: Gerhard
authors.initials: G
authors.lastname: Traxler
authors.affiliation: Department of Neurology, Neuromed Campus - Kepler University Hospital, Wagner Jauregg Weg 15, 4020, Linz, Austria.
authors.forename: Claudia
authors.initials: C
authors.lastname: Dorninger
authors.affiliation: Department of Neurology, Neuromed Campus - Kepler University Hospital, Wagner Jauregg Weg 15, 4020, Linz, Austria. hanspeter.haring@gespag.at.
authors.forename: Hans-Peter
authors.identifier: http://orcid.org/0000-0003-0654-6963
authors.initials: HP
authors.lastname: Haring
mesh_terms: D000368:Aged; D001317:Austria / Q000453:epidemiology; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000401:mortality* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality* / Q000517:prevention & control; D015995:Prevalence; D012041:Regional Medical Programs / Q000706:statistics & numerical data*; D012042:Registries; D012307:Risk Factors; D015996:Survival Rate; D017131:Thrombectomy / Q000401:mortality* / Q000706:statistics & numerical data*; D016896:Treatment Outcome
keywords: Endovascular treatment; Interventional neuroradiology; Ischemic stroke; Stroke network; Thrombectomy