title: Palladium(ii)-catalyzed direct O-alkenylation of 2-arylquinazolinones with N-tosylhydrazones: an efficient route to O-alkenylquinazolines.
abstract: An efficient Pd(ii)-catalyzed direct O-alkenylation of 2-arylquinazolinones with simple ketone-derived N-tosylhydrazones is reported. In this reaction, O-alkenylquinazolines were obtained in good yields, with excellent functional group tolerance. Pd-carbene migratory insertion is proposed as the key step in the reaction mechanism.
authors.affiliation: Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, India. nagaiah@iict.res.in nagasaisrikari@gmail.com.
authors.forename: Rajaka
authors.initials: R
authors.lastname: Lingayya
authors.forename: Mari
authors.initials: M
authors.lastname: Vellakkaran
authors.forename: Kommu
authors.initials: K
authors.lastname: Nagaiah
authors.forename: Prabhakar Rao
authors.initials: PR
authors.lastname: Tadikamalla
authors.forename: Jagadeesh Babu
authors.initials: JB
authors.lastname: Nanubolu