title: Changes in Molecular Characteristics of Mycoplasma pneumoniae in Clinical Specimens from Children in Beijing between 2003 and 2015.
abstract: The molecular characteristics of 480 Mycoplasma pneumoniae polymerase chain reaction-positive specimens (331 were previously reported and 149 were newly reported) collected from pediatric patients in Beijing, China, between 2003 and 2015 were analyzed. Genotype M4-5-7-2/P1 were the most prevalent across the 13-year study period, although the isolation and mutation rates for this genotype varied between the periods 2003-2007, 2008-2013, and 2014-2015. In addition, there was a close association between the M4-5-7-2 genotype and macrolide resistance.
authors.affiliation: Department of Bacteriology, Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Sun
authors.affiliation: Department of Bacteriology, Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
authors.forename: Guanhua
authors.initials: G
authors.lastname: Xue
authors.affiliation: Department of Bacteriology, Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Yan
authors.affiliation: Department of Bacteriology, Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
authors.forename: Shaoli
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Bacteriology, Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
authors.forename: Hanqing
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Department of Bacteriology, Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
authors.forename: Yanling
authors.initials: Y
authors.lastname: Feng
authors.affiliation: Department of Bacteriology, Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
authors.forename: Liqiong
authors.initials: L
authors.lastname: Wang
mesh_terms: D002648:Child; D002681:China; D024881:Drug Resistance, Bacterial / Q000235:genetics; D005798:Genes, Bacterial; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000187:drug effects / Q000235:genetics*