title: Determination of Tryptamines and β-Carbolines in Ayahuasca Beverage Consumed During Brazilian Religious Ceremonies.
abstract: Ayahuasca is a potent hallucinogenic beverage prepared from Banisteriopsis caapi in combination with other psychoactive plants. N,N-dimethyltryptamine, tryptamine, harmine, harmaline, harmalol, and tetrahydroharmine were quantified in ayahuasca samples using a simple and low-cost method based on SPE and LC with UV diode-array detection. The experimental variables that affect the SPE method, such as type of solid phase and nature of solvent, were optimized. The method showed good linearity (r > 0.9902) and repeatability (RSD < 0.8%) for alkaloid compounds, with an LOD of 0.12 mg/L. The proposed method was used to analyze 20 samples from an ayahuasca cooking process from a religious group located in the municipality of Fortaleza, state of Ceará, Brazil. The results showed that concentrations of the target compounds ranged from 0.3 to 36.7 g/L for these samples.
authors.affiliation: Universidade Federal de Sergipe, Departamento de Química, Av Marechal Rondon, s/n, 49100-000, São Cristóvão-Se, Brazil.
authors.forename: Mônica Cardoso
authors.initials: MC
authors.lastname: Santos
authors.affiliation: Universidade Federal de Sergipe, Departamento de Química, Av Marechal Rondon, s/n, 49100-000, São Cristóvão-Se, Brazil.
authors.forename: Sandro
authors.initials: S
authors.lastname: Navickiene
authors.affiliation: Instituto Federal de Educação, Ciência e Tecnologia de Sergipe, Br 101, Km 96, 49100-000, São Cristóvão-Se, Brazil.
authors.forename: Alain
authors.initials: A
authors.lastname: Gaujac
mesh_terms: D031581:Banisteriopsis / Q000737:chemistry*; D001628:Beverages / Q000032:analysis*; D001938:Brazil; D002243:Carbolines / Q000032:analysis*; D006213:Hallucinogens / Q000032:analysis*; D014363:Tryptamines / Q000032:analysis*
chemical_list: D002243:Carbolines; D006213:Hallucinogens; D014363:Tryptamines