title: Clinical and histopathological features of asymptomaticpersistent microscopic hematuria in children.
abstract: OBJECTIVE
  We analyzed the clinical and pathological features and prognosis of 106 children with persistent asymptomatic microscopic hematuria (PAMH) with or without mild proteinuria.
  
  
  METHODS
  This was a retrospective study of 106 children who were referred to our clinics from 2000 to 2013 for evaluation of PAMH.
  
  
  RESULTS
  Among the 106 patients, 69 (65%) were female and 37 (35%) were male. The patients were divided into two groups: 101 patients with isolated microscopic hematuria (IMH) and 5 patients with asymptomatic microscopic hematuria and mild proteinuria (AMHP). Renal biopsy was performed in all 5 children with AHMP: 2 patients had hereditary nephropathy and 2 patients had focal segmental glomerulosclerosis (FSGS). One biopsy specimen revealed nonspecific findings. Renal biopsy was performed in 9 children with IMH: 4 patients had hereditary nephropathy and 5 patients had nonspecific findings. None of the patients received any specific treatment prior to renal biopsy. During the follow-up period, none of the patients developed impaired renal function. Among all the children, only one patient with AMHP developed hypertension and 2 patients with IMH developed proteinuria.
  
  
  CONCLUSIONS
  Long-term follow-up must be done carefully for isolated microscopic hematuria and renal biopsy should be performed in selected cases.
authors.affiliation: Department of Pediatric Nephrology, School of Medicine, Marmara University, İstanbul, Turkey.
authors.forename: Serçin
authors.initials: S
authors.lastname: Güven
authors.affiliation: Department of Pediatric Nephrology, School of Medicine, Marmara University, İstanbul, Turkey.
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Gökçe
authors.affiliation: Department of Pediatric Nephrology, School of Medicine, Marmara University, İstanbul, Turkey.
authors.forename: Neslihan Çiçek
authors.initials: NÇ
authors.lastname: Deniz
authors.affiliation: Department of Pediatric Nephrology, School of Medicine, Marmara University, İstanbul, Turkey.
authors.forename: Ülger
authors.initials: Ü
authors.lastname: Altuntaş
authors.affiliation: Department of Pediatric Nephrology, School of Medicine, Marmara University, İstanbul, Turkey.
authors.forename: Nurdan
authors.initials: N
authors.lastname: Yıldız
authors.affiliation: Department of Pediatric Nephrology, School of Medicine, Marmara University, İstanbul, Turkey.
authors.forename: Harika
authors.initials: H
authors.lastname: Alpay
mesh_terms: D001706:Biopsy; D002648:Child; D005260:Female; D006417:Hematuria; D006801:Humans; D007668:Kidney; D007674:Kidney Diseases; D008297:Male; D011507:Proteinuria; D012189:Retrospective Studies
keywords: Hematuria; proteinuria; renal biopsy