title: Oxygen saturation, periodic breathing, and sleep apnea in infants aged 1-4 months old living at 3200 meters above sea level.
abstract: To describe, in infants aged 1-4 months old living at 3200 meters above sea level (MASL), oxygen saturation (SpO2), sleep apnea indices, and periodic breathing (PB) during sleep. Polysomnographies were done in 18 healthy infants.
  
  
  
  The median SpO2 was 87%, and the median PB was 7.2% for the total sleep time. The median central sleep apnea index was 30.5/hour, which decreased to 5.4/hour once sleep apneas associated with PB were excluded. The 5th percentile for SpO2 was 76% among awake infants, and 66% among asleep infants.
  
  
  
  The SpO2 was lower than that observed at sea level, whereas PB and the central sleep apnea index were higher, once sleep apneas associated with PB were excluded. The latter was similar to that observed at sea level. At 3200 MASL, different cut-off points are required for a normal SpO2, one for infants during the waking state and one for infants during sleep.
authors.affiliation: Departamento de Pediatría, Fundación Santa Fe de Bogotá, Bogotá, Colombia. santiago_ucros@yahoo.com.
authors.forename: Santiago
authors.initials: S
authors.lastname: Ucrós
authors.affiliation: Departamentos de Pediatría y Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Claudia
authors.initials: C
authors.lastname: Granados
authors.affiliation: Departamento de Neurología y Laboratorio de Sueño, Fundación Clínica Shaio, Bogotá, Colombia.
authors.forename: Karem
authors.initials: K
authors.lastname: Parejo
authors.affiliation: Departamento de Pediatría, Hospital Luis Fernando Martínez, Cañar, Ecuador.
authors.forename: Fausto
authors.initials: F
authors.lastname: Ortega
authors.affiliation: Departamento de Pediatría, Hospital del Río, Universidad del Azuay, Cuenca, Ecuador.
authors.forename: Fernando
authors.initials: F
authors.lastname: Guillén
authors.affiliation: Departamentos de Pediatría, Hospital de La Misericordia y Fundación Santa Fe de Bogotá, Universidad de los Andes, Bogotá, Colombia.
authors.forename: Sonia
authors.initials: S
authors.lastname: Restrepo
authors.affiliation: Departamento de Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Fabián
authors.initials: F
authors.lastname: Gil
authors.affiliation: Estudiante de Medicina, Universidad del Azuay, Cuenca, Ecuador.
authors.forename: Miriam
authors.initials: M
authors.lastname: Guillén
mesh_terms: D000531:Altitude; D003105:Colombia; D003430:Cross-Sectional Studies; D004484:Ecuador; D006801:Humans; D007223:Infant; D010100:Oxygen / Q000378:metabolism*; D011446:Prospective Studies; D012119:Respiration; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000378:metabolism* / Q000503:physiopathology*
chemical_list: D010100:Oxygen
keywords: altitude; infant; oximetry; polysomnography; sleep