title: Potential relationship between periodontal diseases and eye diseases.
abstract: Periodontal diseases are inflammatory lesions initiated by oral bacteria and lead to the destruction of the supporting structures of the teeth (gingiva, periodontal ligament and alveolar bone) in susceptible patient. Via several biological mechanisms, periodontal diseases have been associated with multiple systemic diseases, such as rheumatoid arthritis, diabetes, cardiovascular diseases, Alzheimer's disease and adverse pregnancy outcomes. Similarly certain eye diseases have been associated with systemic diseases of the inflammatory pathway. We hypothesized that periodontal diseases are associated with eye diseases. Thus using literature data we find that several studies have reported that eye disorders are associated with the presence of periodontal diseases. But the mechanisms of this relationship are not clear. However the innate immune response involvement, the sharing of similar risk factors in pathogenesis and the changes of eye choroid thickness may be suggested as several hypotheses to explain this potential association.
authors.affiliation: UIC Odontology, CHU NANTES, LIOAD Inserm U791, Faculty of Dental Surgery, University of Nantes, 1 place Alexis Ricordeau, 44200 Nantes, France.
authors.forename: Z A D
authors.initials: ZA
authors.lastname: Pockpa
authors.affiliation: Department of Periodontology, Faculty of Dental Surgery, University of Nantes, UIC Odontology, CHU NANTES, LIOAD Inserm U791, Faculty of Dental Surgery, University of Nantes, 1 place Alexis Ricordeau, 44200 Nantes, France.
authors.forename: X
authors.initials: X
authors.lastname: Struillou
authors.affiliation: Department of Periodontology, Faculty of Dental Surgery, University of Felix Houphouët Boigny, CHU COCODY, 22 BP 612 Abidjan 22, Cote d'Ivoire.
authors.forename: N T
authors.initials: NT
authors.lastname: Coulibaly
authors.affiliation: Department of Ophthalmology, CHU NANTES, 1 place Alexis Ricordeau, 44200 Nantes, France.
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.affiliation: Department of Periodontology, Faculty of Dental Surgery, University of Nantes, UIC Odontology, CHU NANTES, LIOAD Inserm U791, Faculty of Dental Surgery, University of Nantes, 1 place Alexis Ricordeau, 44200 Nantes, France. Electronic address: assem.soueidan@univ-nantes.fr.
authors.forename: A
authors.initials: A
authors.lastname: Soueidan
authors.affiliation: Department of Periodontology, Faculty of Dental Surgery, University of Nantes, UIC Odontology, CHU NANTES, LIOAD Inserm U791, Faculty of Dental Surgery, University of Nantes, 1 place Alexis Ricordeau, 44200 Nantes, France.
authors.forename: Z
authors.initials: Z
authors.lastname: Badran
mesh_terms: D002829:Choroid / Q000378:metabolism; D015897:Comorbidity; D003165:Complement System Proteins / Q000502:physiology; D005128:Eye Diseases / Q000150:complications*; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D007249:Inflammation; D008297:Male; D008962:Models, Theoretical; D010510:Periodontal Diseases / Q000150:complications*; D011247:Pregnancy; D012160:Retina / Q000502:physiology; D012307:Risk Factors
chemical_list: D003165:Complement System Proteins