title: Using game theory to investigate the epigenetic control mechanisms of embryo development: Comment on: "Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition" by Qian Wang et al.
abstract: A body of research [1-7] has already shown that epigenetic reprogramming plays a critical role in maintaining the normal development of embryos. However, the mechanistic quantitation of the epigenetic interactions between sperms and oocytes and the related impact on embryo development are still not clear [6,7]. In this study, Wang et al., [8] develop a modeling framework that addresses this question by integrating game theory and the latest discoveries of the epigenetic control of embryo development.
authors.affiliation: College of Computer and Information Science, Southwest University, Chongqing, 400715, PR China. Electronic address: zhanglcq@swu.edu.cn.
authors.forename: Le
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Institute of Digital Medicine, Third Military Medical University, Chongqing, 400038, PR China. Electronic address: zhangcvh@aliyun.com.
authors.forename: Shaoxiang
authors.initials: S
authors.lastname: Zhang
mesh_terms: D047108:Embryonic Development; D044127:Epigenesis, Genetic; D005716:Game Theory; D008297:Male; D009865:Oocytes; D015053:Zygote
keywords: Embryo development; Epigenetic reprogramming; Game theory