title: Interstitial Pneumonia Associated with the Influenza Vaccine: A Report of Two Cases.
abstract: Although the influenza vaccine is relatively safe and effective, serious complications can develop in rare cases. We encountered two cases of interstitial pneumonia that developed after vaccination during the 2014-2015 influenza season. Overall, nine cases, including the two presented here, have been recorded in PubMed and the Cochrane library; eight patients were treated with corticosteroids, and all nine survived, suggesting a good prognosis. Interstitial pneumonia is rare; however, we found an increase in its incidence after 2009. Therefore, clinicians must be aware of the possibility of this complication and duly educate all patients in advance.
authors.affiliation: Department of Respiratory Medicine, Shonan Fujisawa Tokushukai Hospital, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Hibino
authors.forename: Tetsuri
authors.initials: T
authors.lastname: Kondo
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000009:adverse effects*; D007251:Influenza, Human / Q000517:prevention & control*; D017563:Lung Diseases, Interstitial / Q000139:chemically induced / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D007252:Influenza Vaccines