title: Current Strategies for the Immunotherapy of Multiple Myeloma.
abstract: The introduction of cellular immunotherapies using genetically modified T cells has revolutionized the treatment of patients with B-cell lymphomas. However, despite the progress made in this field, similarly effective immunotherapeutic approaches have not yet been identified for patients with solid tumors or other hematologic malignancies such as multiple myeloma. Here we outline the most promising novel cellular immune strategies for patients with multiple myeloma. In addition, we highlight combinatorial approaches that, it is hoped, will further optimize cellular immunotherapies for myeloma and lead to deep and durable responses and, possibly, even cures.
authors.forename: Tim
authors.initials: T
authors.lastname: Luetkens
authors.forename: Sara
authors.initials: S
authors.lastname: Yousef
authors.forename: Sabarinath Venniyil
authors.initials: SV
authors.lastname: Radhakrishnan
authors.forename: Djordje
authors.initials: D
authors.lastname: Atanackovic
mesh_terms: D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D016246:Lymphocytes, Tumor-Infiltrating / Q000276:immunology; D009101:Multiple Myeloma / Q000276:immunology / Q000628:therapy*; D011948:Receptors, Antigen, T-Cell / Q000235:genetics / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000276:immunology
chemical_list: D011948:Receptors, Antigen, T-Cell; D011993:Recombinant Fusion Proteins