title: Elizabeth Usher Memorial Lecture: Rethinking the clinical pathway for autism spectrum disorder and challenging the status quo.
abstract: Autism spectrum disorder (ASD) is typically diagnosed between 2 and 5 years of age, which is currently thought to be the earliest that the behavioural symptoms are able to be identified without ambiguity. A significant problem with this relatively "late" age of diagnosis is that by the time a child has been identified and diagnosed with ASD, many of the best opportunities for therapies to capitalise upon brain plasticity very early in development are not realised. This paper provides an overview of the benefits and drawbacks of the current clinical pathway that places primacy on a diagnostic assessment for triggering the commencement of therapy. The paper then presents an alternative clinical pathway - the identification and provision of therapy to infants at risk of ASD - and provides a critical review of current evidence supporting this model. The aim of the paper is to outline a vision for the future of early identification and intervention of individuals with ASD, and the research goals that need to be addressed to achieve this vision.
authors.affiliation: a Telethon Kids Institute, The University of Western Australia , Subiaco , Australia.
authors.forename: Andrew J O
authors.initials: AJO
authors.lastname: Whitehouse
mesh_terms: D000067877:Autism Spectrum Disorder / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D001521:Behavior Therapy / Q000379:methods*; D001921:Brain / Q000254:growth & development*; D002652:Child Behavior; D002657:Child Development; D002675:Child, Preschool; D019091:Critical Pathways; D042241:Early Diagnosis; D061345:Early Medical Intervention / Q000379:methods*; D006801:Humans; D007223:Infant; D018730:Infant Behavior; D009473:Neuronal Plasticity; D011237:Predictive Value of Tests; D012307:Risk Factors; D013066:Speech-Language Pathology / Q000379:methods*; D016896:Treatment Outcome
keywords: Autism spectrum disorders; clinical pathway; early intensive behavioural intervention