title: The factors affecting survival in patients with bronchiectasis.
abstract: OBJECTIVE
  There is limited information about the rate and modifiers of mortality in noncystic fibrosis bronchiectasis.
  
  
  METHODS
  This study enrolled a total of 56 bronchiectasis patients. Patients' body mass index, smoking habit, previous therapies, comorbid disorders, history of vaccination, bronchiectasis type and radiological extent, arterial blood gas analysis, respiratory function tests, and laboratory results were recorded.
  
  
  RESULTS
  After a follow-up of 65.38 ± 18.62 months the overall mortality rate was 35.7%. The mean survival duration was 46.42 ± 8.25 months. Advanced age significantly increased mortality (HR: 2.031; CI: 0.991-4.072, P = 0.035). A significant correlation was found between mortality rate and the partial oxygen pressure level (HR: 0.886 (CI: 0.817-0.960); P = 0.039). Pulmonary artery pressure was directly proportional to mortality rate (HR: 9.015 (CI: 3.272-94.036); P = 0.03). There was also a significant correlation between Pseudomonas aeruginosa proliferation in sputum and mortality (HR: 7.014 (CI: 2.812-17.962); P = 0.00). Comorbidities increased mortality (HR: 1.984 (CI: 0.972-2.996); P = 0.04).
  
  
  CONCLUSIONS
  Bronchiectasis is a disease with high mortality. Advanced age, comorbid conditions, reduced partial oxygen pressure, pulmonary hypertension, and Pseudomonas aeruginosa proliferation in sputum increase its mortality rate.
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Fatma
authors.initials: F
authors.lastname: Çiftçi
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Elif
authors.initials: E
authors.lastname: Şen
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Sevgi Behiye
authors.initials: SB
authors.lastname: Saryal
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Zeynep Pınar
authors.initials: ZP
authors.lastname: Önen
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Banu
authors.initials: B
authors.lastname: Gülbay
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Öznur
authors.initials: Ö
authors.lastname: Yıldız
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Turan
authors.initials: T
authors.lastname: Acıcan
authors.affiliation: Department of Chest Disease, Faculty of Medicine, Ankara University, Ankara, Turkey.
authors.forename: Gülseren
authors.initials: G
authors.lastname: Karabıyıkoğlu
mesh_terms: D001987:Bronchiectasis; D006801:Humans; D011552:Pseudomonas Infections; D011550:Pseudomonas aeruginosa; D012129:Respiratory Function Tests; D013183:Sputum
keywords: Bronchiectasis survival; Pseudomonas aeruginosa; mortality