title: Determination of Organophosphorous Pesticides in Environmental Water Samples Using Surface-Engineered C18 Functionalized Silica-Coated Core-Shell Magnetic Nanoparticles-Based Extraction Coupled with GC-MS/MS Analysis.
abstract: The present paper depicts a novel method based on magnetic SPE (MSPE) for the determination of organophosphorus pesticides (OPs) such as phorate, malathion, and chlorpyrifos in environmental water samples. In this study, C18 functionalized silica-coated core-shell iron oxide magnetic nanoparticles (MNPs) were used as a surface-engineered magnetic sorbent for the selective extraction of pesticides from aqueous samples, followed by GC-MS and GC-tandem MS analysis for confirmative determination of the analytes. Various important method parameters, including quantity of MNP adsorbent, volume of sample, effective time for extraction, nature of the desorbing solvent, and pH of the aqueous sample, were investigated and optimized to obtain maximum method performance. Under the optimized instrumental analysis conditions, good linearity (r2 value ≥0.994) was achieved at the concentration range of 0.5-500 μg/L. Recoveries were in the range of 79.2-96.3 and 80.4-97.5% in selective-ion monitoring and multiple reaction monitoring (MRM) modes, respectively, at the spiking concentrations of 1, 5, and 10 μg/L. MRM mode showed better sensitivity, selectivity, and low-level detection (0.5 μg/L) of analytes. The novel MSPE method is a simple, cheap, rapid, and eco-friendly method for the determination of OPs in environmental water samples.
authors.affiliation: Institute of Pesticide Formulation Technology, Analytical Division, Sector-20, Udyog Vihar, Opposite Ambience Mall, NH-8 Gurgaon, Haryana, India.
authors.forename: Neha
authors.initials: N
authors.lastname: Srivastava
authors.affiliation: Institute of Pesticide Formulation Technology, Analytical Division, Sector-20, Udyog Vihar, Opposite Ambience Mall, NH-8 Gurgaon, Haryana, India.
authors.forename: Supriya
authors.initials: S
authors.lastname: Kumari
authors.affiliation: Institute of Pesticide Formulation Technology, Analytical Division, Sector-20, Udyog Vihar, Opposite Ambience Mall, NH-8 Gurgaon, Haryana, India.
authors.forename: Kishore
authors.initials: K
authors.lastname: Nair
authors.affiliation: Institute of Pesticide Formulation Technology, Analytical Division, Sector-20, Udyog Vihar, Opposite Ambience Mall, NH-8 Gurgaon, Haryana, India.
authors.forename: Samsul
authors.initials: S
authors.lastname: Alam
authors.affiliation: Institute of Pesticide Formulation Technology, Analytical Division, Sector-20, Udyog Vihar, Opposite Ambience Mall, NH-8 Gurgaon, Haryana, India.
authors.forename: Syed K
authors.initials: SK
authors.lastname: Raza
mesh_terms: D008401:Gas Chromatography-Mass Spectrometry; D058185:Magnetite Nanoparticles; D009943:Organophosphorus Compounds / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D012822:Silicon Dioxide; D053719:Tandem Mass Spectrometry; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D058185:Magnetite Nanoparticles; D009943:Organophosphorus Compounds; D010575:Pesticides; D014874:Water Pollutants, Chemical; D012822:Silicon Dioxide