title: Systemic medications used in treatment of common dermatological conditions: safety profile with respect to pregnancy, breast feeding and content in seminal fluid.
abstract: Prescribing for pregnant or lactating patients and male patients wishing to father children can be a difficult area for dermatologists. There is a lack of review articles of commonly used systemic medications in dermatology with respect to their effects on developing embryogenesis and their potential transfer across the placenta, in breast milk and in seminal fluid. This paper aims to provide an up to date summary of evidence to better equip dermatologists to inform patients about the effects of systemic medications commonly used in dermatology to treat conditions such as atopic dermatitis, psoriasis and acne, on current and future embryogenesis and fertility.
authors.affiliation: a Dermatology Department , Royal Victoria Infirmary , Newcastle Upon Tyne , UK.
authors.forename: Sarah Madeline
authors.initials: SM
authors.lastname: Brown
authors.affiliation: a Dermatology Department , Royal Victoria Infirmary , Newcastle Upon Tyne , UK.
authors.forename: Khadija
authors.initials: K
authors.lastname: Aljefri
authors.affiliation: a Dermatology Department , Royal Victoria Infirmary , Newcastle Upon Tyne , UK.
authors.forename: Rachel
authors.initials: R
authors.lastname: Waas
authors.affiliation: a Dermatology Department , Royal Victoria Infirmary , Newcastle Upon Tyne , UK.
authors.forename: Philip
authors.initials: P
authors.lastname: Hampton
mesh_terms: D000328:Adult; D001942:Breast Feeding; D003879:Dermatologic Agents / Q000009:adverse effects*; D003880:Dermatology / Q000379:methods; D005260:Female; D005298:Fertility / Q000187:drug effects; D006801:Humans; D007774:Lactation; D008297:Male; D011247:Pregnancy; D012661:Semen / Q000187:drug effects; D013723:Teratogens / Q000494:pharmacology
chemical_list: D003879:Dermatologic Agents; D013723:Teratogens
keywords: Pregnancy; biologics; breastfeeding; retinoids; seminal fluid