title: Schinortriterpenoids: A Case Study in Synthetic Design.
abstract: Since the pioneering days of total synthesis and retrosynthetic analysis, the community has embraced guiding principles for planning synthetic approaches towards complex natural products. These guideposts have enabled the community to synthesize ever more complex compounds by applying prior knowledge gained in new settings. The recently isolated schinortriterpenoid family of natural products has attracted considerable synthetic attention and provided a rich opportunity to evaluate the lessons learned in the construction of complex, polycyclic scaffolds. In this Minireview, a detailed discussion of the synthetic work within this family is provided, including the six reported total syntheses, as well as a comparative analysis of the approaches utilized in their construction.
authors.affiliation: Chemistry Department, Oregon State University, Gilbert Hall Room 153, Corvallis, OR, 9733I, USA.
authors.forename: Xin
authors.identifier: 0000-0002-8840-0695
authors.initials: X
authors.lastname: Li
authors.affiliation: Chemistry Department, Oregon State University, Gilbert Hall Room 153, Corvallis, OR, 9733I, USA.
authors.forename: Paul Ha-Yeon
authors.identifier: 0000-0001-6705-2962
authors.initials: PH
authors.lastname: Cheong
authors.affiliation: Chemistry Department, Oregon State University, Gilbert Hall Room 153, Corvallis, OR, 9733I, USA.
authors.forename: Rich G
authors.identifier: 0000-0002-9100-1791
authors.initials: RG
authors.lastname: Carter
keywords: asymmetric synthesis; natural products; schinortriterpenoids; total synthesis