title: Extreme leukocytosis and leukemoid reaction associated with the lung sarcomatoid carcinoma: an unusual case report.
abstract: OBJECTIVE
  To report a rare case of extreme leukocytosis and leukemoid reaction associated with lung sarcomatoid carcinoma (LSC) and increase people's awareness of the disease.
  
  
  METHODS
  A 58-year-old male patient was diagnosed with LSC; however, after the end of the second course of chemotherapy, his white blood cells increased gradually without fever or use of medications such as granulocyte colony-stimulating factor and steroids. A bone marrow biopsy then confirmed it to be a leukemoid reaction.
  
  
  RESULTS
  The patient died of multiple organ failure 2 months after being diagnosed with leukocytosis.
  
  
  CONCLUSIONS
  LSC associated with leukemoid reaction is very rare and the prognosis is poor. When a patient's white blood cells are extremely elevated, we should think of the possible causes of the tumor itself and identify it with other diseases. However, more data and evidence are still needed to find an effective adjuvant therapy for these patients.
authors.affiliation: Department of Hematopathy, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Danyang
authors.initials: D
authors.lastname: Wang
authors.affiliation: Department of Hematopathy, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Hematopathy, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Fengkuan
authors.initials: F
authors.lastname: Yu
authors.affiliation: Department of Hematopathy, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
authors.forename: Baijun
authors.initials: B
authors.lastname: Fang
keywords: leukemoid reaction; lung sarcomatoid carcinoma