title: Miniaturized and integrated whole cell living bacterial sensors in field applicable autonomous devices.
abstract: Live-cell based bioreporters are increasingly being deployed in microstructures, which facilitates their handling and permits the development of instruments that could perform autonomous environmental monitoring. Here we review recent developments of on-chip integration of live-cell bioreporters, the coupling of their reporter signal to the devices, their longer term preservation and multi-analyte capacity. We show examples of instruments that have attempted to fully integrate bioreporters as their sensing elements.
authors.affiliation: Department of Fundamental Microbiology, University of Lausanne, 1015 Lausanne, Switzerland.
authors.forename: Clémence
authors.initials: C
authors.lastname: Roggo
authors.affiliation: Department of Fundamental Microbiology, University of Lausanne, 1015 Lausanne, Switzerland. Electronic address: janroelof.vandermeer@unil.ch.
authors.forename: Jan Roelof
authors.initials: JR
authors.lastname: van der Meer
mesh_terms: D001419:Bacteria / Q000145:classification / Q000235:genetics; D015374:Biosensing Techniques; D004784:Environmental Monitoring; D017930:Genes, Reporter