title: Quality of Life after Intestinal Resection in Patients with Crohn Disease: A Systematic Review.
abstract: OBJECTIVE
  Most patients with Crohn disease (CD) require surgery within 10 years of diagnosis. Intestinal resection is the most commonly performed operation although the effects on health-related quality of life (HRQOL), particularly long-term, are contentious.
  
  
  METHODS
  We conducted a systematic review evaluating the impact of intestinal resection on the HRQOL of CD patients, predictors of postoperative HRQOL, and patient satisfaction with surgery.
  
  
  RESULTS
  Nine studies including 1,108 CD patients undergoing intestinal resection were identified as eligible for inclusion. The median age at surgery was 29-41 years with varying follow-up period (range 30 days-5 years). Ileocolic resection was the most commonly performed operation on an elective basis (range 95-100%). HRQOL improved as early as 2 weeks postoperatively and lasted up to 5 years across both generic and gastrointestinal domains. Gender, smoking, and disease recurrence were potential predictors of postoperative HRQOL. Patient satisfaction is high with regard to surgery, with preference for a laparoscopic approach.
  
  
  CONCLUSIONS
  Intestinal resection in CD patients improved HRQOL in the short- and long-term and patients describe high satisfaction about their surgery. Further studies are needed to validate potential predictors of postoperative HRQOL in this cohort.
authors.affiliation: Faculty of Medicine, Nursing and Health Sciences, Monash Rural Health, Joanna Briggs Centre, Monash University, Moe, VIC, Australia.
authors.forename: Francis J
authors.initials: FJ
authors.lastname: Ha
authors.forename: Louisa
authors.initials: L
authors.lastname: Thong
authors.forename: Hanan
authors.initials: H
authors.lastname: Khalil
mesh_terms: D003082:Colectomy; D003424:Crohn Disease / Q000601:surgery*; D006801:Humans; D007082:Ileum / Q000601:surgery; D017060:Patient Satisfaction; D016737:Proctocolectomy, Restorative; D011788:Quality of Life; D012008:Recurrence; D012737:Sex Factors; D012907:Smoking
keywords: Crohn disease; Intestinal resection; Quality of life; Surgery