title: Successful surgical management of congenital Kasabach-Merritt syndrome.
abstract: Since the first description of Kasabach-Merritt syndrome (KMS) in 1940, many treatments have been proposed combining pharmacologic and non-pharmacologic approaches, which can be effective on the pathology but can have adverse and unpredictable side-effects with long-term use. Herein we describe the solely surgical treatment of Kasabach-Merritt syndrome in a neonate with a severe and rapidly progressive thrombocytopenia. The patient's condition normalized at 7 days postoperatively, with rapid increase in platelet count and normalization of d-dimer concentration.
authors.affiliation: Pediatric Plastic Surgery Department, Timone Enfants University Hospital, Marseille, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Pascal
authors.affiliation: Pediatric Plastic Surgery Department, Timone Enfants University Hospital, Marseille, France.
authors.forename: Quentin
authors.initials: Q
authors.lastname: Bettex
authors.affiliation: Pediatric Oncology Department, Timone Enfants University Hospital, Marseille, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Andre
authors.affiliation: Pediatric Imaging Department, Timone Enfants University Hospital, Marseille, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Petit
authors.affiliation: Plastic Surgery Department, La Conception Hospital, Marseille, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Casanova
authors.affiliation: Pediatric Plastic Surgery Department, Timone Enfants University Hospital, Marseille, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Degardin
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D059885:Kasabach-Merritt Syndrome / Q000150:complications / Q000601:surgery*; D008297:Male; D013921:Thrombocytopenia / Q000150:complications; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler
keywords: Kasabach-Merritt; congenital; management; surgery; syndrome