title: Three-year postoperative outcomes between MIS and conventional TLIF in1-segment lumbar disc herniation.
abstract: OBJECTIVE
  The aim of this study is to assess the long-term clinical and radiological outcomes between minimally invasive (MIS) and conventional transforaminal lumbar interbody fusion (TLIF) in treating one-segment lumbar disc herniation (LDH).
  
  
  METHODS
  One-hundred and six patients treated by MIS-TLIF (50 cases) or conventional TLIF (56 cases) were included. Perioperative results were evaluated. Clinical outcomes were compared preoperatively and postoperatively. Radiologic parameters were based on a comparison of preoperative and three-year postoperative lumbar lordosis, segmental lordosis, sacral slope, the cross-sectional area of the paraspinal muscle and fusion rates.
  
  
  RESULTS
  MIS TILF had significantly less blood, shorter operation time, mean return to work time and lower intramuscular pressure compared with the conventional group during the operation. VAS scores for lower back pain and ODI in MIS-TLIF were significantly decreased. The mean cross-sectional area of the paraspinal muscle was significantly decreased after surgery in the conventional TLIF group and no significant intragroup differences were established in the MIS-TLIF group. No significant differences were found in fusion rate, lumbar lordosis, segmental lordosis and sacral slope.
  
  
  CONCLUSIONS
  Both MIS and conventional TLIF were beneficial for patients with LDH. However, MIS-TLIF manifests a great improvement in perioperative outcomes, low back pain, disability and preventing paraspinal muscle atrophy during the follow-up period observation.
authors.affiliation: a Department of Orthopedics , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: You
authors.initials: Y
authors.lastname: Lv
authors.affiliation: b Department of Orthopedics , Ningbo Medical Center Lihuili Eastern Hosipital , Zhejiang , China.
authors.forename: Jingyang
authors.initials: J
authors.lastname: Chen
authors.affiliation: a Department of Orthopedics , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: Jinchuan
authors.initials: J
authors.lastname: Chen
authors.affiliation: c Department of Nursing , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: Yuling
authors.initials: Y
authors.lastname: Wu
authors.affiliation: d Department of Orthopedics , Affiliated Hospital of Xuzhou Medical University , Jiangsu , China.
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Chen
authors.affiliation: a Department of Orthopedics , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.affiliation: a Department of Orthopedics , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: Zhaoming
authors.initials: Z
authors.lastname: Chu
authors.affiliation: a Department of Orthopedics , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: Luxin
authors.initials: L
authors.lastname: Sheng
authors.affiliation: a Department of Orthopedics , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: Rujie
authors.initials: R
authors.lastname: Qin
authors.affiliation: a Department of Orthopedics , The First People's Hospital of Lianyungang , Jiangsu , China.
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
mesh_terms: D016063:Blood Loss, Surgical; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000601:surgery*; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D008141:Lordosis / Q000453:epidemiology; D017116:Low Back Pain / Q000453:epidemiology; D008159:Lumbar Vertebrae / Q000601:surgery; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D061646:Operative Time; D011446:Prospective Studies; D062707:Return to Work / Q000706:statistics & numerical data; D013123:Spinal Fusion / Q000379:methods*; D016896:Treatment Outcome
keywords: Minimally invasive; ODI; VAS; low back pain; transforaminal lumbar interbody fusion