title: Glycoproteins functionalized natural and synthetic polymers for prospective biomedical applications: A review.
abstract: Glycoproteins have multidimensional properties such as biodegradability, biocompatibility, non-toxicity, antimicrobial and adsorption properties; therefore, they have wide range of applications. They are blended with different polymers such as chitosan, carboxymethyl cellulose (CMC), polyvinyl pyrrolidone (PVP), polycaprolactone (PCL), heparin, polystyrene fluorescent nanoparticles (PS-NPs) and carboxyl pullulan (PC) to improve their properties like thermal stability, mechanical properties, resistance to pH, chemical stability and toughness. Considering the versatile charateristics of glycoprotein based polymers, this review sheds light on synthesis and characterization of blends and composites of glycoproteins, with natural and synthetic polymers and their potential applications in biomedical field such as drug delivery system, insulin delivery, antimicrobial wound dressing uses, targeting of cancer cells, development of anticancer vaccines, development of new biopolymers, glycoproteome research, food product and detection of dengue glycoproteins. All the technical scientific issues have been addressed; highlighting the recent advancement.
authors.affiliation: Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
authors.forename: Shazia
authors.initials: S
authors.lastname: Tabasum
authors.affiliation: Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
authors.forename: Aqdas
authors.initials: A
authors.lastname: Noreen
authors.affiliation: Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
authors.forename: Arooj
authors.initials: A
authors.lastname: Kanwal
authors.affiliation: Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zuber
authors.affiliation: Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
authors.forename: Muhammad Naveed
authors.initials: MN
authors.lastname: Anjum
authors.affiliation: Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan. Electronic address: ziakmpkpolym@yahoo.com.
authors.forename: Khalid Mahmood
authors.initials: KM
authors.lastname: Zia
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D001704:Biopolymers / Q000737:chemistry / Q000627:therapeutic use; D002266:Carboxymethylcellulose Sodium / Q000737:chemistry / Q000627:therapeutic use; D048271:Chitosan / Q000737:chemistry / Q000627:therapeutic use; D016503:Drug Delivery Systems; D006023:Glycoproteins / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use; D011091:Polyesters / Q000737:chemistry / Q000627:therapeutic use; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D011205:Povidone / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D001672:Biocompatible Materials; D001704:Biopolymers; D006023:Glycoproteins; D011091:Polyesters; D011108:Polymers; C016240:polycaprolactone; D048271:Chitosan; D011205:Povidone; D002266:Carboxymethylcellulose Sodium
keywords: Blends and composites; Cancer treatment; Drug delivery system; Glycoproteins; Tissue engineering