title: Current and Emerging Technology for Continuous Glucose Monitoring.
abstract: Diabetes has become a leading cause of death worldwide. Although there is no cure for diabetes, blood glucose monitoring combined with appropriate medication can enhance treatment efficiency, alleviate the symptoms, as well as diminish the complications. For point-of-care purposes, continuous glucose monitoring (CGM) devices are considered to be the best candidates for diabetes therapy. This review focuses on current growth areas of CGM technologies, specifically focusing on subcutaneous implantable electrochemical glucose sensors. The superiority of CGM systems is introduced firstly, and then the strategies for fabrication of minimally-invasive and non-invasive CGM biosensors are discussed, respectively. Finally, we briefly outline the current status and future perspective for CGM systems.
authors.affiliation: School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. chencheng@sspu.edu.cn.
authors.forename: Cheng
authors.initials: C
authors.lastname: Chen
authors.affiliation: School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. xlzhao@sspu.edu.cn.
authors.forename: Xue-Ling
authors.initials: XL
authors.lastname: Zhao
authors.affiliation: School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. zhli@sspu.edu.cn.
authors.forename: Zhan-Hong
authors.initials: ZH
authors.lastname: Li
authors.affiliation: School of Environmental and Materials Engineering, College of Engineering, Shanghai Polytechnic University, Shanghai 201209, China. zgzhu@sspu.edu.cn.
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Zhu
authors.affiliation: Department of Ophthalmology, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200231, China. qsh2304@163.com.
authors.forename: Shao-Hong
authors.initials: SH
authors.lastname: Qian
authors.affiliation: Electrical Engineering Division, Department of Engineering, University of Cambridge, J J Thomson Avenue, Cambridge CB3 0FA, UK. ajf@eng.cam.ac.uk.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Flewitt
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D003920:Diabetes Mellitus; D006801:Humans; D008991:Monitoring, Physiologic; D019095:Point-of-Care Systems
chemical_list: D001786:Blood Glucose
keywords: continuous glucose monitoring; glucose biosensor; implanted devices; mini-invasive; non-invasive