title: Cationic AuIIIversus AuI: Catalyst-Controlled Divergent Reactivity of Alkyne-Tethered Lactams.
abstract: Switchable reactivity through cationic gold-based catalyst control built on the oxidation state, namely cationic AuIIIversus AuI, has been achieved in the direct functionalization of 2-azetidinone-tethered alkynyl indoles.
authors.affiliation: Grupo de LactamasyHeterociclos Bioactivos, Unidad Asociada al CSIC, Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
authors.forename: Benito
authors.identifier: http://orcid.org/0000-0002-2180-9605
authors.initials: B
authors.lastname: Alcaide
authors.affiliation: Instituto de Química Orgánica General, IQOG, Consejo Superior de Investigaciones Científicas, CSIC, Juan de la Cierva 3, 28006, Madrid, Spain.
authors.forename: Pedro
authors.identifier: http://orcid.org/0000-0001-6564-2758
authors.initials: P
authors.lastname: Almendros
authors.affiliation: Grupo de LactamasyHeterociclos Bioactivos, Unidad Asociada al CSIC, Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
authors.forename: Sara
authors.identifier: http://orcid.org/0000-0001-9884-9042
authors.initials: S
authors.lastname: Cembellín
authors.affiliation: Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
authors.forename: Israel
authors.identifier: http://orcid.org/0000-0002-0186-9774
authors.initials: I
authors.lastname: Fernández
authors.affiliation: Grupo de LactamasyHeterociclos Bioactivos, Unidad Asociada al CSIC, Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.
authors.forename: Teresa
authors.identifier: http://orcid.org/0000-0002-8729-4085
authors.initials: T
authors.lastname: Martínez Del Campo
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D001384:Azetidines / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D002412:Cations / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D007769:Lactams / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: C116379:2-azetidinone; D000480:Alkynes; D001384:Azetidines; D002412:Cations; D007211:Indoles; D007769:Lactams; D006046:Gold
keywords: allenes; gold; heterocycles; selectivity; synthetic methods