title: Update on advanced melanoma treatments: small molecule targeted therapy, immunotherapy, and future combination therapies.
abstract: Early stage melanomas can achieve remarkable outcomes with surgery alone, but stage IV metastatic melanoma requires significant intervention and has poor outcomes. Here we present evidence on the latest advances in melanoma treatment, discuss the scientific concepts behind new therapies, and analyze the potential of future treatment combinations.
authors.affiliation: Keck School of Medicine of USC (University of Southern California), Los Angeles, CA, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Kwong
authors.affiliation: Department of Medical Sciences, Section of Dermatology, University of Turin, Turin, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Sanlorenzo
authors.affiliation: Rudolfstiftung Hospital, Academic Teaching Hospital, Medical University Vienna, Juchgasse 25, Vienna, 1030, Austria.
authors.forename: Klemens
authors.initials: K
authors.lastname: Rappersberger
authors.affiliation: Rudolfstiftung Hospital, Academic Teaching Hospital, Medical University Vienna, Juchgasse 25, Vienna, 1030, Austria. igor.vujic.md@gmail.com.|School of Medicine, Sigmund Freud University Vienna, Vienna, Austria. igor.vujic.md@gmail.com.
authors.forename: Igor
authors.initials: I
authors.lastname: Vujic
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D007167:Immunotherapy; D008545:Melanoma / Q000628:therapy; D058990:Molecular Targeted Therapy
keywords: Efficacy; Immunotherapy; Malignant melanoma; Targeted molecular therapy; Therapy