title: Enamel remineralization effect of a dentifrice containing calcium sodium phosphosilicate: an optical coherence tomography observation.
abstract: OBJECTIVE
  The purpose of this study was to examine the effects of a dentifrice containing 5% calcium sodium phosphosilicate (CSP) on the remineralization of the enamel using optical coherence tomography (OCT).
  
  
  METHODS
  Bovine incisors were sliced and shaped in a rectangular form. One group of five specimens was treated with undersaturated 0.1 M lactic acid buffer solution (pH 4.75) for 10 min and then placed in artificial saliva (pH 7.0) (De group). Other specimens were stored in solutions of toothpaste containing CSP for 10 min, followed by 10-min immersion in the lactic acid buffer solution twice a day before storage in artificial saliva (CSP group). An additional group was stored in only artificial saliva (control group). OCT imaging on the selected location of the enamel surface was performed. The peak intensity and width at 1/e2were recorded in each of the six areas on the sample and averaged, and the sample size of each group was six. The integrated value in units (dB × μm) was calculated in the area of peak intensity. The data for each group was subjected to one-way repeated-measures ANOVA and Tukey HSD tests (α = 0.05).
  
  
  RESULTS
  The changes in integrated values of each group were different. A slight but significant increase in the integrated value was observed in the control group, whereas a slight but significant decrease in the value was observed the De group. Integrated values increased in the CSP group.
  
  
  CONCLUSIONS
  Remineralization occurred upon immersion in the toothpaste containing CSP.
authors.affiliation: a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
authors.forename: Saki
authors.initials: S
authors.lastname: Matsuyoshi
authors.affiliation: a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Murayama
authors.affiliation: a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Akiba
authors.affiliation: a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
authors.forename: Chiaki
authors.initials: C
authors.lastname: Yabuki
authors.affiliation: a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
authors.forename: Toshiki
authors.initials: T
authors.lastname: Takamizawa
authors.affiliation: a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Kurokawa
authors.affiliation: a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Miyazaki
mesh_terms: D000818:Animals; D002130:Calcium Phosphates / Q000627:therapeutic use*; D002417:Cattle; D003743:Dental Enamel / Q000187:drug effects*; D003802:Dentifrices / Q000494:pharmacology / Q000627:therapeutic use*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D012464:Saliva, Artificial; D012969:Sodium Fluoride; D041623:Tomography, Optical Coherence / Q000379:methods*; D017001:Tooth Demineralization / Q000517:prevention & control*; D014089:Tooth Remineralization / Q000379:methods; D014100:Toothpastes
chemical_list: D002130:Calcium Phosphates; D003802:Dentifrices; D057133:Dentin Desensitizing Agents; D012464:Saliva, Artificial; D014100:Toothpastes; D012969:Sodium Fluoride
keywords: Calcium sodium phosphosilicate; dentifrice; optical coherence tomography; remineralization