title: Dopaminergic rules of engagement for memory in Drosophila.
abstract: Dopamine is associated with a variety of conserved responses across species including locomotion, sleep, food consumption, aggression, courtship, addiction and several forms of appetitive and aversive memory. Historically, dopamine has been most prominently associated with dynamics underlying reward, punishment, or salience. Recent emerging evidence from Drosophila supports a role in all of these functions, as well as additional roles in the interplay between external sensation and internal states and forgetting of the very memories dopamine helped encode. We discuss how cell-specific resolution and manipulation are elucidating the rules of dopamine's involvement in encoding valence and memory.
authors.affiliation: Department of Neuroscience, Brown University, Providence, RI 02912, United States. Electronic address: karla_kaun@brown.edu.
authors.forename: Karla R
authors.initials: KR
authors.lastname: Kaun
authors.affiliation: Department of Psychiatry, University of Utah Molecular Medicine Program, Salt Lake City, UT 84113, United States.
authors.forename: Adrian
authors.initials: A
authors.lastname: Rothenfluh
mesh_terms: D000818:Animals; D004298:Dopamine / Q000378:metabolism*; D004330:Drosophila / Q000502:physiology*; D008568:Memory / Q000502:physiology*; D011678:Punishment; D012201:Reward
chemical_list: D004298:Dopamine