title: Technical Note: Measurement of common carotid artery lumen dynamics using black-blood MR cine imaging.
abstract: OBJECTIVE
  To demonstrate the feasibility of measuring the common carotid artery (CCA) lumen dynamics using a black-blood cine (BB-cine) imaging method.
  
  
  METHODS
  Motion-sensitized driven-equilibrium (MSDE) prepared spoiled gradient sequence was used for the BB-cine imaging. CCAs of eleven healthy volunteers were studied using this method. Lumen dynamics, including lumen area evolution waveforms and distension values, were measured and evaluated by comparing this method with bright-blood cine (BrB-cine) imaging.
  
  
  RESULTS
  Compared with the BrB-cine images, flow artifacts were effectively suppressed in the BB-cine images. BrB-cine images generally show larger lumen areas than BB-cine images. The lumen area waveforms and distension measurements from BB-cine imaging showed smaller variances among different subjects than BrB-cine imaging.
  
  
  CONCLUSIONS
  The proposed BB-cine imaging technique can suppress the flow artifacts effectively and reduce the partial volume effects from the vessel wall. This might allow more accurate lumen dynamics measurements than traditional BrB-cine imaging, which may further be valuable for investigating biomechanical and functional properties of the cardiovascular system.
authors.affiliation: Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Erpeng
authors.initials: E
authors.lastname: Dai
authors.affiliation: Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
authors.forename: Li
authors.initials: L
authors.lastname: Dong
authors.affiliation: Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Lyu
authors.initials: L
authors.lastname: Li
authors.affiliation: Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Xihai
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Clinical Sites Research Program, Philips Research North America, Briarcliff Manor, NY, 10510, USA.
authors.forename: Jinnan
authors.initials: J
authors.lastname: Wang
authors.affiliation: Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.|Department of Radiology, University of Washington, Seattle, WA, 98109, USA.
authors.forename: Chun
authors.initials: C
authors.lastname: Yuan
authors.affiliation: Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Guo
mesh_terms: D000293:Adolescent; D000328:Adult; D016477:Artifacts; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000502:physiology; D005240:Feasibility Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009038:Motion; D012039:Regional Blood Flow; D015203:Reproducibility of Results; D055815:Young Adult
keywords: 
  MSDE
  ; black-blood cine imaging; bright-blood cine imaging; common carotid artery; lumen dynamics