title: Barriers and enablers of the prevention of mother-to-child transmission of HIV/AIDS program in China: a systematic review and policy implications.
abstract: OBJECTIVE
  To identify the barriers to and enablers of the prevention of mother-to-child transmission (PMTCT) of HIV program in China.
  
  
  METHODS
  A systematic review of the existing literature regarding barriers to and enablers of the implementation of the PMTCT program in China was performed. The checklist from the SURE guidelines (Supporting the Use of Research Evidence) was used to synthesize the barriers and enablers (supporting strategies) and to analyze their relationships. The HIV testing rate, vertical transmission rate, and antiretroviral treatment (ART) acceptance rate among HIV-infected women and their infants was also extracted from the included studies to assess the effectiveness of the enablers.
  
  
  RESULTS
  Initially 794 publications were identified, and ultimately 14 articles were included. Eighteen types of barrier and nine types of supportive strategy were identified, mainly at the level of social and political issues, healthcare recipients, healthcare providers, and the healthcare system. Based on government-oriented multi-sector cooperation, enablers in China have included community-hospital-family promotion, comprehensive financial support for service recipients, free HIV testing at marriage registration, the opt-out model, and the one-to-one service model.
  
  
  CONCLUSIONS
  Experience in China suggests that the government's role in coordination and the acceptability and accessibility of the service should be the primary concerns in regard to the PMTCT project.
authors.affiliation: Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China.
authors.forename: Zhuoxin
authors.initials: Z
authors.lastname: Peng
authors.affiliation: Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China.
authors.forename: Shengnan
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China.
authors.forename: Biao
authors.initials: B
authors.lastname: Xu
authors.affiliation: Department of Epidemiology, Fudan University,138 Yi Xue Yuan Road, Shanghai 200032, China. Electronic address: wwb@fudan.edu.cn.
authors.forename: Weibing
authors.initials: W
authors.lastname: Wang
mesh_terms: D000328:Adult; D002648:Child; D002681:China; D005260:Female; D015658:HIV Infections / Q000635:transmission*; D006801:Humans; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D009035:Mothers; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*
keywords: Barriers; China; Enablers; HIV; PMTCT; Policy implications