title: Hormone therapy in transgender adults is safe with provider supervision; A review of hormone therapy sequelae for transgender individuals.
abstract: BACKGROUND
  Some providers report concern for the safety of transgender hormone therapy (HT).
  
  
  METHODS
  This is a systematic literature review of HT safety for transgender adults.
  
  
  RESULTS
  Current literature suggests HT is safe when followed carefully for certain risks. The greatest health concern for HT in transgender women is venous thromboembolism. HT among transgender men appears to cause polycythemia. Both groups experienced elevated fasting glucose. There is no increase in cancer prevalence or mortality due to transgender HT.
  
  
  CONCLUSIONS
  Although current data support the safety of transgender HT with physician supervision, larger, long-term studies are needed in transgender medicine.
authors.affiliation: Transgender Medicine Research Group, Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA.
authors.forename: Jamie D
authors.initials: JD
authors.lastname: Weinand
authors.affiliation: Transgender Medicine Research Group, Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA.
authors.forename: Joshua D
authors.initials: JD
authors.lastname: Safer
keywords: Hormone therapy; Review; Safety; Transgender; Transsexual