title: All that is old does not wither: Conservation of outer kinetochore proteins across all eukaryotes?
abstract: The kinetochore drives faithful chromosome segregation in all eukaryotes, yet the underlying machinery is diverse across species. D'Archivio and Wickstead (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608043) apply sensitive homology predictions to identify proteins in kinetoplastids with similarity to canonical outer kinetochore proteins, suggesting some degree of universality in the eukaryotic kinetochore.
authors.affiliation: Institut Curie, Paris Sciences et Lettres Research University, Centre National de la Recherche Scientifique UMR 3664, F-75005 Paris, France.|Sorbonne Universités, University Pierre-and-Marie-Curie, F-75005 Paris, France.
authors.forename: Aruni P
authors.initials: AP
authors.lastname: Senaratne
authors.affiliation: Institut Curie, Paris Sciences et Lettres Research University, Centre National de la Recherche Scientifique UMR 3664, F-75005 Paris, France ines.drinnenberg@curie.fr.
authors.forename: Ines A
authors.identifier: 0000-0002-9649-0352
authors.initials: IA
authors.lastname: Drinnenberg
mesh_terms: D020090:Chromosome Segregation; D056890:Eukaryota; D018386:Kinetochores; D011506:Proteins
chemical_list: D011506:Proteins