title: Three-dimensional quality assurance of IMRT prostate plans using gel dosimetry.
abstract: Intensity modulated radiotherapy (IMRT) is one of the most modern radiation therapy treatment techniques. Although IMRT can deliver high and complex conformational doses to the tumor volume, its implementation requires rigorous quality assurance (QA) procedures that include a dosimetric pre-treatment verification of individual patient planning. This verification usually involves measuring a small volume of absolute dose with an ionization chamber and checking bi-dimensional fluency with an array of detectors. The planning technique has tri-dimensional characteristics, but no tridimensional dosimetry has been established in the clinical routine. One strategy to perform three-dimensional dosimetry is to use polymeric gels associated with magnetic resonance imaging to evaluate dose distribution. Here, we have compared the results of conventional QA procedures involving one- and two-dimensional dosimetry to the results of three-dimensional dosimetry conducted with MAGIC-f gel in 10 cases of prostate cancer IMRT planning. More specifically, we used the gamma index (3%/3mm) to compare the results of three-dimensional dosimetry to the expected dose distributions obtained with the treatment planning system. Except for one IMRT treatment plan, the gel dosimetry results agreed with the conventional quality control and provided an overview of dose distribution in the target volume.
authors.affiliation: Departamento de Física, FFCLRP, Universidade de São Paulo, Av. Bandeirantes 3900, 14040-901, Monte Alegre, Ribeirão Preto, SP, Brazil.
authors.forename: M A
authors.initials: MA
authors.lastname: Silveira
authors.affiliation: Departamento de Física, FFCLRP, Universidade de São Paulo, Av. Bandeirantes 3900, 14040-901, Monte Alegre, Ribeirão Preto, SP, Brazil. Electronic address: jfpavoni@ffclrp.usp.br.
authors.forename: J F
authors.initials: JF
authors.lastname: Pavoni
authors.affiliation: Departamento de Física, FFCLRP, Universidade de São Paulo, Av. Bandeirantes 3900, 14040-901, Monte Alegre, Ribeirão Preto, SP, Brazil.
authors.forename: O
authors.initials: O
authors.lastname: Baffa
mesh_terms: D002138:Calibration; D005782:Gels; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D011785:Quality Assurance, Health Care; D011874:Radiometry; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated
chemical_list: D005782:Gels
keywords: Gel dosimetry; MAGIC-f; Prostate IMRT; Tridimensional dosimetry