title: Effectiveness of telephone-based interventions on health-related quality of life and prognostic outcomes in breast cancer patients and survivors-A meta-analysis.
abstract: The aim of this meta-analysis was to evaluate the effect of telephone-based interventions on prognostic outcomes and health-related quality of life (HRQoL) in breast cancer patients and survivors. A systematic search of the Cochrane Library, Web of science, Medline, EMBASE, CNKI and CBM database was carried out. Randomised, controlled trials (RCTs) examining the effects of telephone-based intervention versus a control group receiving no telephone intervention, on prognostic outcomes and HRQoL with breast cancer were included. A meta-analysis was conducted to quantify the effects of telephone-based interventions on anxiety, depression, fatigue, self-efficiency, physiological function, social-domestic function and quality of life. In total, 14 studies involving 2002 participants were included. Due to the effect of telephone-based interventions, statistically significant results were found on anxiety (standard mean difference [SMD] = -0.16, 95% confidence intervals [CI] [0.01, 0.30], p = .04), self-efficiency (SMD = 0.22, 95% CI [-0.34, -0.10], p = .0004), social-domestic function (SMD = 0.19, 95% CI [-0.35, -0.03], p = .02) and quality of life (SMD = 0.54, 95% CI [-1.00, -0.08], p = .02). Although the effects on depression, fatigue and physiological function were in the expected direction, these effects were not statistically significant (p > .05) based on the insufficient evidence.
authors.affiliation: Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.|School of Nursing, Nantong University, Nantong, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.|School of Nursing, Nantong University, Nantong, China.
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.|School of Nursing, Nantong University, Nantong, China.
authors.forename: R
authors.initials: R
authors.lastname: Yin
authors.affiliation: Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.|School of Nursing, Nantong University, Nantong, China.
authors.forename: T
authors.initials: T
authors.lastname: Fu
authors.affiliation: Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, China.
authors.forename: B
authors.initials: B
authors.lastname: Shen
mesh_terms: D001007:Anxiety / Q000523:psychology; D001943:Breast Neoplasms / Q000523:psychology*; D003376:Counseling / Q000379:methods*; D003863:Depression / Q000523:psychology; D005221:Fatigue / Q000523:psychology; D005260:Female; D006801:Humans; D011379:Prognosis; D011788:Quality of Life; D020377:Self Efficacy; D017741:Survivors / Q000523:psychology*; D013689:Telephone
keywords: breast cancer; health-related quality of life; meta-analysis; prognostic outcomes; telephone-based interventions