title: Anatomic Considerations for Sinonasal and Ventral Skull Base Malignancy.
abstract: Malignancies of the sinonasal region and ventral skull base include a varied group of uncommon tumors that are a challenge to treat. These malignancies, with few exceptions, often present late because of their insidious growth and bland symptomatology. As with malignancies of other sites, the primary goal in surgical management is complete resection with negative margins. This presents a unique surgical challenge in that these lesions lie within a region of densely populated anatomic real estate. This fact reinforces the importance of complete preoperative work-up and a sound anatomic understanding. This article discusses key anatomic regions and their importance from an endonasal perspective.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, UPMC Eye & Ear Institute, University of Pittsburgh Medical Center, Suite 500, 203 Lothrop Street, Pittsburgh, PA 15213, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Willson
authors.affiliation: Department of Neurological Surgery, UPMC Presbyterian, University of Pittsburgh Medical Center, Suite B-400, 200 Lothrop Street, Pittsburgh, PA 15213, USA. Electronic address: fernandezmirandajc@upmc.edu.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Fernandez-Miranda
authors.affiliation: Department of Neurological Surgery, UPMC Presbyterian, University of Pittsburgh Medical Center, Suite B-400, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
authors.forename: Cristian
authors.initials: C
authors.lastname: Ferrareze Nunes
authors.affiliation: Department of Neurological Surgery, UPMC Presbyterian, University of Pittsburgh Medical Center, Suite B-400, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
authors.forename: Stefan
authors.initials: S
authors.lastname: Lieber
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, UPMC Eye & Ear Institute, University of Pittsburgh Medical Center, Suite 500, 203 Lothrop Street, Pittsburgh, PA 15213, USA.
authors.forename: Eric W
authors.initials: EW
authors.lastname: Wang
mesh_terms: D004724:Endoscopy; D006801:Humans; D008443:Maxillary Sinus / Q000033:anatomy & histology* / Q000601:surgery; D009296:Nasal Cavity / Q000033:anatomy & histology* / Q000601:surgery; D009669:Nose Neoplasms / Q000601:surgery*; D019291:Skull Base / Q000033:anatomy & histology* / Q000601:surgery; D019292:Skull Base Neoplasms / Q000601:surgery*; D014057:Tomography, X-Ray Computed
keywords: Anatomy; Endonasal; Endoscopic; Skullbase