title: Characteristics and Survival Determinants in Patients After Out-of-Hospital Cardiac Arrest in The Era of 24/7 Coronary Intervention Facilities.
abstract: BACKGROUND
  Survival rates and outcomes after out-of-hospital cardiac arrest (OHCA) remain low despite investments of time and money. The goal of this analysis was to identify variables related to survival of patients transferred to our coronary care unit (CCU) after an OHCA.
  
  
  METHODS
  102 consecutive OHCA patients, mean age 64.6 (SD 13.3), 70.6% men, between January, 2011 and December, 2013, who were transferred to our tertiary care CCU, were studied.
  
  
  RESULTS
  Cardiac-cause OHCA was present in 84 patients (82.4%). Of these 60.7% had an acute coronary syndrome (ACS) - STEMI 35.7%; NSTEMI 23.8%. Coronary angiography was performed in 73 (71.6%) patients - 81% with cardiac- and 31.3% (5/16) with a non-cardiac cause. Percutaneous coronary intervention (PCI) was performed in 50 patients (68.5%), 49 with cardiac-cause, and succeeded in 92%. In-hospital mortality was 38.2%, one-year mortality was 51.5%. In-hospital and one-year mortality were related to age (p=0.002 resp. p=0.001), first ECG rhythm (p=0.001, resp. p=0.005), history of coronary artery disease (RR 2.1; p=0.026 resp. RR 1.71; p=0.029), and history of arrhythmia (supraventricular tachyarrhythmia, bradyarrhythmia) (RR 2.74; p=0.003 resp. RR 2.3; p=0.001). One-year mortality was also related to a history of diabetes mellitus (RR 1.89; p=0.006).
  
  
  CONCLUSIONS
  Cardiac-cause was the most common cause of OHCA. Acute coronary syndrome was present in more than half of the cases. Availability of interventional facilities was a crucial factor in OHCA management. A history of coronary artery disease, diabetes mellitus, and arrhythmia were associated with worse survival.
authors.affiliation: Cardiocenter, 3(rd) Department of Internal Medicine - Cardiology, 3(rd) Medical School, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic.
authors.forename: Josef
authors.initials: J
authors.lastname: Kroupa
authors.affiliation: Cardiocenter, 3(rd) Department of Internal Medicine - Cardiology, 3(rd) Medical School, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic.
authors.forename: Jiri
authors.initials: J
authors.lastname: Knot
authors.affiliation: Cardiocenter, 3(rd) Department of Internal Medicine - Cardiology, 3(rd) Medical School, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic.
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Ulman
authors.affiliation: Cardiocenter, 3(rd) Department of Internal Medicine - Cardiology, 3(rd) Medical School, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic.
authors.forename: Frantisek
authors.initials: F
authors.lastname: Bednar
authors.affiliation: Institute of Physiology, 1(st) Medical School, Charles University, Prague, Czech Republic.
authors.forename: Alena
authors.initials: A
authors.lastname: Dohnalova
authors.affiliation: Cardiocenter, 3(rd) Department of Internal Medicine - Cardiology, 3(rd) Medical School, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic. Electronic address: motovska.zuzana@gmail.com.
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Motovska
mesh_terms: D000368:Aged; D016208:Databases, Factual; D018572:Disease-Free Survival; D017052:Hospital Mortality; D006801:Humans; D008875:Middle Aged; D058687:Out-of-Hospital Cardiac Arrest / Q000401:mortality* / Q000601:surgery*; D062645:Percutaneous Coronary Intervention; D012307:Risk Factors; D015996:Survival Rate
keywords: Acute coronary syndrome; Coronary angiography; Echocardiography; Mortality; Out-of-hospital cardiac arrest; Survival