title: Recent advances in the management of liposarcoma.
abstract: Liposarcoma is the most common soft tissue sarcoma. With its various subtypes, the natural history of this disease can vary significantly from a locally recurrent tumor to a highly malignant one carrying a poor prognosis. Progress in the understanding of the specific molecular abnormalities in liposarcoma provides greater opportunity for new treatment modalities. Although surgical resection and radiation therapy remain the keystones for the management of primary liposarcoma, the inclusion of novel agents that target known abnormalities in advanced liposarcoma enhances the potential for improved outcomes.
authors.affiliation: Hoag Family Cancer Institute, Hoag Hospital, Newport Beach, CA, USA; Orthopedic Research and Education Institute, Sand Canyon Avenue, Irvine, CA, USA; Hoag Orthopedic Institute, Sand Canyon Avenue, Irvine, CA, USA.
authors.forename: Nadar A
authors.initials: NA
authors.lastname: Nassif
authors.affiliation: Hoag Family Cancer Institute, Hoag Hospital, Newport Beach, CA, USA; Department of Surgery, Section of Surgical Oncology, Keck School of Medicine, University of Southern California, San Pablo, Los Angeles, California, USA.
authors.forename: William
authors.initials: W
authors.lastname: Tseng
authors.affiliation: Orthopedic Research and Education Institute, Sand Canyon Avenue, Irvine, CA, USA.
authors.forename: Camille
authors.initials: C
authors.lastname: Borges
authors.affiliation: Hoag Family Cancer Institute, Hoag Hospital, Newport Beach, CA, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: Chen
authors.affiliation: Hoag Family Cancer Institute, Hoag Hospital, Newport Beach, CA, USA; Department of Surgery, Section of Surgical Oncology, Keck School of Medicine, University of Southern California, San Pablo, Los Angeles, California, USA; USC Norris Cancer Center, Los Angeles, California, USA.
authors.forename: Burton
authors.initials: B
authors.lastname: Eisenberg
keywords: liposarcoma; palbociclib; radiation therapy; soft tissue sarcoma; surgical resection