title: Effects of a Home-Based Family-Centred Early Habilitation Program on Neurobehavioural Outcomes of Very Preterm Born Infants: A Retrospective Cohort Study.
abstract: Preterm children have an increased risk of neurodevelopmental impairments which include psychomotor and language retardation. The objectives of the present retrospective cohort study were to examine the effects of an individually adapted, home-based, and family-centred early developmental habilitation program on neurodevelopmental and behavioural outcomes of very preterm children compared with a standard follow-up at 2 years' corrected age. Enrolled infants were retrospectively assigned to the intervention group (61 subjects) or to the control group (62 subjects) depending on whether they had or had not carried out a home-based family-centred early developmental habilitation program focused on environmental enrichment, parent-guided environmental interaction, and infant development. Developmental outcome was assessed for both groups at 24 months' corrected age using the Bayley Scales of Infant Development 2nd Edition. Intervention significantly improved both cognitive and behavioural outcomes. In addition, males had significantly lower scores than females either before or after treatment. However, the treatment was effective in both genders to the same extent. In conclusion, a timely updated environment suitable to the infant's developmental needs could provide the best substrate where the parent-infant relationship can be practised with the ultimate goal of achieving further developmental steps.
authors.affiliation: Unità Operativa Neuropsichiatria Infanzia e Adolescenza (UONPIA), ASST Fatebenefratelli e Sacco, 20157 Milano, Italy.
authors.forename: Michela
authors.initials: M
authors.lastname: Poggioli
authors.affiliation: Unit of Environmental Epidemiology, Institute of Clinical Physiology, National Council of Research, 56124 Pisa, Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Minichilli
authors.affiliation: Unità Operativa Neuropsichiatria Infanzia e Adolescenza (UONPIA), ASST Fatebenefratelli e Sacco, 20157 Milano, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Bononi
authors.affiliation: Unità Operativa Neuropsichiatria Infanzia e Adolescenza (UONPIA), ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.
authors.forename: Pasquina
authors.initials: P
authors.lastname: Meghi
authors.affiliation: Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Andre
authors.affiliation: Department of Translational Research on New Technologies in Medicine and Surgery, School of Physical Medicine and Rehabilitation, University of Pisa, 56126 Pisa, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Crecchi
authors.affiliation: Department of Translational Research on New Technologies in Medicine and Surgery, School of Physical Medicine and Rehabilitation, University of Pisa, 56126 Pisa, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Rossi
authors.affiliation: Department of Translational Research on New Technologies in Medicine and Surgery, School of Physical Medicine and Rehabilitation, University of Pisa, 56126 Pisa, Italy.
authors.forename: Maria Chiara
authors.initials: MC
authors.lastname: Carboncini
authors.affiliation: Unità Operativa Neuropsichiatria Infanzia e Adolescenza (UONPIA), ASST Fatebenefratelli e Sacco, 20157 Milano, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Ottolini
authors.affiliation: Department of Translational Research on New Technologies in Medicine and Surgery, School of Physical Medicine and Rehabilitation, University of Pisa, 56126 Pisa, Italy.
authors.forename: Luca
authors.identifier: 0000-0001-5097-1014
authors.initials: L
authors.lastname: Bonfiglio
mesh_terms: D002657:Child Development / Q000502:physiology*; D015331:Cohort Studies; D061345:Early Medical Intervention / Q000379:methods*; D004777:Environment; D022143:Family Nursing / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006699:Home Care Services; D006801:Humans; D007223:Infant; D062071:Infant, Extremely Premature / Q000502:physiology* / Q000523:psychology; D007231:Infant, Newborn; D008297:Male; D010287:Parent-Child Relations; D012189:Retrospective Studies; D016896:Treatment Outcome