title: The American College of Radiology and the American Brachytherapy Society practice parameter for the performance of radionuclide-based high-dose-rate brachytherapy.
abstract: Brachytherapy is a radiation therapy method in which radionuclide sources are used to deliver a radiation dose at a distance of up to a few centimeters by surface, intracavitary, intraluminal, or interstitial application. This practice parameter refers only to the use of radionuclides for brachytherapy. Brachytherapy alone or combined with external beam therapy plays an important role in the management and treatment of patients with cancer. High-dose-rate (HDR) brachytherapy uses radionuclides such as iridium-192 at dose rates of 20 cGy per minute (12 Gy per hour) or more to a designated target point or volume. High-dose-rate (HDR) brachytherapy is indicated for treating malignant or benign tumors where the treatment volume or targeted points are defined and accessible.
authors.affiliation: Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address: berickson@mcw.edu.
authors.forename: Beth A
authors.initials: BA
authors.lastname: Erickson
authors.affiliation: Tacoma Valley Radiation Oncology Centers, Tacoma, WA, USA.
authors.forename: Nathan H J
authors.initials: NH
authors.lastname: Bittner
authors.affiliation: Mount Sinai Beth Israel, New York, NY, USA.
authors.forename: Manjeet
authors.initials: M
authors.lastname: Chadha
authors.affiliation: Helen F. Graham Cancer Center & Research Institute, Christiana Care Health System, Newark, DE, USA.
authors.forename: Firas
authors.initials: F
authors.lastname: Mourtada
authors.affiliation: UCLA Health System, Los Angeles, CA, USA.
authors.forename: D Jeffrey
authors.initials: DJ
authors.lastname: Demanes
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D006282:Health Personnel / Q000592:standards; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D009369:Neoplasms / Q000532:radiotherapy*; D018579:Patient Selection; D018787:Radiation Oncology; D011868:Radioisotopes / Q000627:therapeutic use; D011871:Radiology; D011879:Radiotherapy Dosage; D012955:Societies, Medical; D014481:United States
chemical_list: D007496:Iridium Radioisotopes; D011868:Radioisotopes
keywords: HDR brachytherapy; High-dose-rate brachytherapy; Oncologic practice; Radiation oncologist; Radiation therapy; Radioactive sources; Radionuclides