title: Essential oil constituents and antimicrobial activity of Pycnocycla bashagardiana Mozaff. from Iran.
abstract: Pycnocycla bashagardiana is a rare endemic and endangered species that has been used in folkloric medicine in Southern Iran. This study aimed to evaluate the essential oil constituents and antimicrobial activity of wild and cultivated p. bashagardiana. The aerial parts of wild and cultivated plants were collected from two provinces of Iran. The essential oil was isolated by hydrodistillation and analyzed by a combination of capillary GC and GC-MS. The main components in wild plants were myristicin (39.12%), (E)-β-ocimene (21.97%), sabinene (15.0%) and cis-iso-miristicin (2.67%) and in cultivated plants, (E)-β-ocimene (55.40%), myristicin (18.27%), (Z)-β-ocimene (12.47%) and cis-iso-miristicin (2.94%) were the main constituents in essential oil. The in vitro antimicrobial activity of the essential oil of P. bashagardiana were studied against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Candida albicans for the first time. The results showed that the oil exhibited strong antimicrobial activity against all the tested pathogens.
authors.affiliation: a Department of Medicinal and Aromatic Plants, Estahban Branch , Islamic Azad University , Estahban , Iran.|b Young Researchers and Elites Club, Estahban Branch , Islamic Azad University , Estahban , Iran.
authors.forename: Ardalan
authors.initials: A
authors.lastname: Alizadeh
authors.affiliation: a Department of Medicinal and Aromatic Plants, Estahban Branch , Islamic Azad University , Estahban , Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Abdollahzadeh
mesh_terms: D000080462:Acyclic Monoterpenes; D000475:Alkenes / Q000032:analysis; D000081248:Allylbenzene Derivatives; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D019661:Apiaceae / Q000737:chemistry*; D001593:Benzyl Compounds / Q000032:analysis; D000081008:Bicyclic Monoterpenes; D002176:Candida albicans / Q000187:drug effects; D004148:Dioxolanes / Q000032:analysis; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004926:Escherichia coli / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D007492:Iran; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D011748:Pyrogallol / Q000031:analogs & derivatives / Q000032:analysis; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000080462:Acyclic Monoterpenes; D000475:Alkenes; D000081248:Allylbenzene Derivatives; D000890:Anti-Infective Agents; D001593:Benzyl Compounds; D000081008:Bicyclic Monoterpenes; D004148:Dioxolanes; D039821:Monoterpenes; D009822:Oils, Volatile; D011748:Pyrogallol; C005246:myristicin; C443996:beta-ocimene; C035127:sabinene
keywords: Pycnocycla bashagardiana; antimicrobial; essentialoil; myristicin