title: ERAD-icating mutant insulin promotes functional insulin secretion.
abstract: Overexpression of a chaperone protein liberates functional insulin from a misfolded mutant partner to improve insulin secretion.
authors.affiliation: Departments of Pediatrics and Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA. Email: daniel.moore@vanderbilt.edu.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Moore
mesh_terms: D004721:Endoplasmic Reticulum; D060746:Endoplasmic Reticulum-Associated Degradation; D007328:Insulin; D000078790:Insulin Secretion; D011384:Proinsulin / Q000235:genetics*; D017510:Protein Folding
chemical_list: D007328:Insulin; D011384:Proinsulin