title: Comparison of Model-Based Iterative Reconstruction, Adaptive Statistical Iterative Reconstruction, and Filtered Back Projection for Detecting Hepatic Metastases on Submillisievert Low-Dose Computed Tomography.
abstract: OBJECTIVE
  The aim of the study was to compare the diagnostic performance of model-based iterative reconstruction (MBIR), adaptive statistical iterative reconstruction (ASIR), and filtered back projection (FBP) on submillisievert low-dose computed tomography (LDCT) for detecting hepatic metastases.
  
  
  METHODS
  Thirty-eight patients having hepatic metastases underwent abdomen CT. Computed tomography protocol consisted of routine standard-dose portal venous phase scan (120 kVp) and 90-second delayed low-dose scan (80 kVp). The LDCT images were reconstructed with FBP, ASIR, and MBIR, respectively. Two readers recorded the number of hepatic metastases on each image set.
  
  
  RESULTS
  A total of 105 metastatic lesions were analyzed. For reader 1, sensitivity for detecting metastases was stationary between FBP (49%) and ASIR (52%, P = 0.0697); however, sensitivity increased in MBIR (66%, P = 0.0035). For reader 2, it was stationary for all the following sets: FBP (65%), ASIR (68%), and MBIR (67%, P > 0.05).
  
  
  CONCLUSIONS
  The MBIR and ASIR showed a limited sensitivity for detecting hepatic metastases in submillisievert LDCT.
authors.affiliation: From the *Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Haeundae-gu, Busan; and †Department of Radiology, Myongji Hospital, Deogyang-gu, Goyang-si, Gyeonggi-do, South Korea.
authors.forename: Jung Hee
authors.initials: JH
authors.lastname: Son
authors.forename: Seung Ho
authors.initials: SH
authors.lastname: Kim
authors.forename: Jung-Hee
authors.initials: JH
authors.lastname: Yoon
authors.forename: Yedaun
authors.initials: Y
authors.lastname: Lee
authors.forename: Yun-Jung
authors.initials: YJ
authors.lastname: Lim
authors.forename: Seon-Jeong
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*