title: Echinococcus granulosusSensu Stricto in Dogs and Jackals from Caspian Sea Region, Northern Iran.
abstract: BACKGROUND
  The aim of the present study was genotyping ofEchinococcus granulosusisolates from dogs and jackals in Mazandaran Province, northern Iran, and using partial sequence of the mitochondrial cytochrome c oxidase subunit 1 gene (cox1).
  
  
  METHODS
  E. granulosusisolates (n = 15) were collected from 42 stray dogs and 16 jackals found in south of the Caspian Sea in northern Iran. After morphological study, the isolates were genetically characterized using consensus sequences (366bp) of thecox1gene. Phylogenetic analysis ofcox1nucleotide sequence data was performed using a Bayesian Inference approach.
  
  
  RESULTS
  Four different sequences were observed among the isolates. Two genotypes [G1 (66.7%) and G3 (33.3%)] were identified among the isolates. The G1 sequences indicated three sequence profiles. One profile (Maz1) had 100% homology with reference sequence (AN: KP339045). Two other profiles, designated Maz2 and Maz3, had 99% homology with the G1 genotype (ANs: KP339046 and KP339047). A G3 sequence designated Maz4 showed 100% homology with a G3 reference sequence (AN: KP339048).
  
  
  CONCLUSIONS
  The occurrence of the G1 genotype ofE. granulosus sensu strictoas a frequent genotype in dogs is emphasized. This study established the first molecular characterization ofE. granulosusin the province.
authors.affiliation: Department of Parasitology & Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Shirzad
authors.initials: S
authors.lastname: Gholami
authors.affiliation: Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Hefzallah
authors.initials: H
authors.lastname: Jahandar
authors.affiliation: Invasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Abastabar
authors.affiliation: Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Abdolsatar
authors.initials: A
authors.lastname: Pagheh
authors.affiliation: Department of Parasitology & Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Iraj
authors.initials: I
authors.lastname: Mobedi
authors.affiliation: Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran; Department of Parasitology & Mycology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
authors.forename: Mitra
authors.initials: M
authors.lastname: Sharbatkhori
keywords: Dog; Echinococcus granulosus; Genotyping; Iran; Jackal; cox1