title: Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions.
abstract: We summarize here the results presented and subsequent discussion from the meeting on Integrating Hebbian and Homeostatic Plasticity at the Royal Society in April 2016. We first outline the major themes and results presented at the meeting. We next provide a synopsis of the outstanding questions that emerged from the discussion at the end of the meeting and finally suggest potential directions of research that we believe are most promising to develop an understanding of how these two forms of plasticity interact to facilitate functional changes in the brain.This article is part of the themed issue 'Integrating Hebbian and homeostatic plasticity'.
authors.affiliation: Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK t.keck@ucl.ac.uk.
authors.forename: Tara
authors.identifier: 0000-0001-6623-1037
authors.initials: T
authors.lastname: Keck
authors.affiliation: RIKEN Brain Science Institute, Wako, Japan.
authors.forename: Taro
authors.identifier: 0000-0001-5444-8829
authors.initials: T
authors.lastname: Toyoizumi
authors.affiliation: Department of Neurosurgery, Stanford University, Stanford, CA, USA.
authors.forename: Lu
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Mathematics, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Brent
authors.initials: B
authors.lastname: Doiron
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.
authors.forename: Daniel E
authors.identifier: 0000-0003-4646-8170
authors.initials: DE
authors.lastname: Feldman
authors.affiliation: Division of Neuroscience, University of Cardiff, Cardiff, Wales, UK.
authors.forename: Kevin
authors.initials: K
authors.lastname: Fox
authors.affiliation: Brain Mind Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
authors.forename: Wulfram
authors.initials: W
authors.lastname: Gerstner
authors.affiliation: Tufts University School of Medicine, Medford, MA, USA.
authors.forename: Philip G
authors.initials: PG
authors.lastname: Haydon
authors.affiliation: Department of Cellular and Systems Neuroscience, Max Planck Institute of Neurobiology, Martinsried, Bayern, Germany.
authors.forename: Mark
authors.initials: M
authors.lastname: Hübener
authors.affiliation: The Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Hey-Kyoung
authors.identifier: 0000-0002-5554-983X
authors.initials: HK
authors.lastname: Lee
authors.affiliation: Department of Biology, Brandeis University, Waltham, MA, USA.
authors.forename: John E
authors.identifier: 0000-0003-2676-225X
authors.initials: JE
authors.lastname: Lisman
authors.affiliation: Department of Cellular and Systems Neuroscience, Max Planck Institute of Neurobiology, Martinsried, Bayern, Germany.
authors.forename: Tobias
authors.identifier: 0000-0002-7156-4714
authors.initials: T
authors.lastname: Rose
authors.affiliation: Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.|Division of Neuroscience, University of Cardiff, Cardiff, Wales, UK.
authors.forename: Frank
authors.identifier: 0000-0002-7060-1851
authors.initials: F
authors.lastname: Sengpiel
authors.affiliation: Centre for Research in Neuroscience, McGill University, Montreal, Quebec, Canada.
authors.forename: David
authors.identifier: 0000-0003-3509-103X
authors.initials: D
authors.lastname: Stellwagen
authors.affiliation: Sandler Neurosciences Center, University of California, San Francisco, CA, USA.
authors.forename: Michael P
authors.identifier: 0000-0003-1546-5831
authors.initials: MP
authors.lastname: Stryker
authors.affiliation: Department of Biology, Brandeis University, Waltham, MA, USA.
authors.forename: Gina G
authors.initials: GG
authors.lastname: Turrigiano
authors.affiliation: School of Informatics, University of Edinburgh, Edinburgh, UK.
authors.forename: Mark C
authors.identifier: 0000-0001-6525-6814
authors.initials: MC
authors.lastname: van Rossum
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D006706:Homeostasis; D006801:Humans; D009473:Neuronal Plasticity
keywords: Hebbian plasticity; homeostatic mechanisms; theoretical modelling