title: Preparation and evaluation of pillararene bonded silica gel stationary phases for high performance liquid chromatography.
abstract: Pillararene bonded stationary phases for high performance liquid chromatography were prepared using 3-aminopropyltriethoxysilane as coupling reagent. The structure of the new materials was characterized by infrared spectroscopy, elemental analysis and thermogravimetric analysis. The chromatographic performance and retention mechanism of the new stationary phases were evaluated in reversed-phase mode compared with C18using different solute probes including Tanaka test solutes, polycyclic aromatic hydrocarbons, phenols and aromatic positional isomers. The new stationary phases could provide various interactions for different solutes, such as hydrophobic, hydrogen bonding, π-π and inclusion interactions. The synergistic effects resulting from aromatic rings, oxygen atoms, alkyl linkers and cavities in the new host molecules improved the separation selectivity by multiple retention mechanisms. Such hybrid stationary phases can provide more versatility and have great potential for the analysis of complex samples.
authors.affiliation: School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450001, PR China; Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, 450001, PR China. Electronic address: wjiezh@126.com.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Zhao
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Jianxiang
authors.initials: J
authors.lastname: Chu
authors.affiliation: Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, 450001, PR China.
authors.forename: Fuwei
authors.initials: F
authors.lastname: Xie
authors.affiliation: School of Material and Chemical Engineering, Henan Institute of Engineering, Zhengzhou 450052, PR China.
authors.forename: Qunpeng
authors.initials: Q
authors.lastname: Duan
authors.affiliation: School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450001, PR China.
authors.forename: Lijun
authors.initials: L
authors.lastname: He
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: zsszz@126.com.
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D007202:Indicators and Reagents; D007536:Isomerism; D010636:Phenols / Q000032:analysis; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis; D011437:Propylamines / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D058428:Silica Gel / Q000737:chemistry*
chemical_list: D007202:Indicators and Reagents; D010636:Phenols; D011084:Polycyclic Aromatic Hydrocarbons; D011437:Propylamines; D012821:Silanes; D058428:Silica Gel; C477625:amino-propyl-triethoxysilane
keywords: Multi-interaction; Pillararene; Reversed-phase chromatography; Stationary phase