title: Propensity score-matching analysis of the efficacy of late cholecystectomy for acute cholecystitis.
abstract: BACKGROUND
  Urgent cholecystectomy within 72 h from symptom onset is recommended. We assessed the feasibility of performing late cholecystectomy (4-7 days from symptom onset) for acute cholecystitis.
  
  
  METHODS
  One hundred sixty-four patients with grades 1 and 2 cholecystitis, who underwent urgent cholecystectomy within 7 days from symptom onset between June 2011 and June 2015 were enrolled. One hundred thirteen patients underwent operation within 72 h from symptom onset (early operation group), and 51 underwent operation between 4 and 7 days (late operation group). Surgical outcomes and postoperative complications were analyzed using propensity score-matching analysis.
  
  
  RESULTS
  The rate of conversion, intraoperative bleeding, and complications were comparable between the groups. After a one-to-two propensity score-matched analysis was performed, outcomes of the late operation group were not inferior to those of the early operation group.
  
  
  CONCLUSIONS
  Late cholecystectomy was acceptable for treating grades 1 and 2 acute cholecystitis.
authors.affiliation: Department of Surgery, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan.
authors.forename: Yu-Ki
authors.initials: YK
authors.lastname: Takemoto
authors.affiliation: Department of Surgery, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan. Electronic address: t.abe.hiroshima@gmail.com.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Abe
authors.affiliation: Department of Surgery, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan; Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi, Minami-ku, Hiroshima, Japan.
authors.forename: Hironobu
authors.initials: H
authors.lastname: Amano
authors.affiliation: Department of Gastroenterology, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Hanada
authors.affiliation: Department of Surgery, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan.
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Fujikuni
authors.affiliation: Department of Surgery, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Yoshida
authors.affiliation: Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi, Minami-ku, Hiroshima, Japan.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kobayashi
authors.affiliation: Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi, Minami-ku, Hiroshima, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Ohdan
authors.affiliation: Department of Surgery, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan; Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi, Minami-ku, Hiroshima, Japan.
authors.forename: Toshio
authors.initials: T
authors.lastname: Noriyuki
authors.affiliation: Department of Surgery, Onomichi General Hospital, Hirahara, Onomichi City, Hiroshima, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakahara
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002763:Cholecystectomy; D041881:Cholecystitis, Acute / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D057216:Propensity Score; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
keywords: Acute cholecystitis; Cholecystectomy; Complications; Late phase; Propensity score