title: Investigation of terahertz radiation influence on rat glial cells.
abstract: We studied an influence of continuous terahertz (THz) radiation (0.12 - 0.18 THz, average power density of 3.2 mW/cm2) on a rat glial cell line. A dose-dependent cytotoxic effect of THz radiation is demonstrated. After 1 minute of THz radiation exposure a relative number of apoptotic cells increased in 1.5 times, after 3 minutes it doubled. This result confirms the concept of biological hazard of intense THz radiation. Diagnostic applications of THz radiation can be restricted by the radiation power density and exposure time.
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia.
authors.forename: Mariia
authors.initials: M
authors.lastname: Borovkova
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia; Immunology Department, Institute of Experimental Medicine, 12 Acad. Pavlov Str., St. Petersburg 197376, Russia.
authors.forename: Maria
authors.initials: M
authors.lastname: Serebriakova
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia; Institute of Laser Physics, 13/3 Lavrentyeva Ave, Novosibirsk 630090, Russia.
authors.forename: Viacheslav
authors.initials: V
authors.lastname: Fedorov
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia.
authors.forename: Egor
authors.initials: E
authors.lastname: Sedykh
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia; Institute for Physics of Microstructures of the Russian Academy of Science, GSP-105, Nizhny Novgorod 603950, Russia.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Vaks
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia.
authors.forename: Alexander
authors.initials: A
authors.lastname: Lichutin
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia.
authors.forename: Alina
authors.initials: A
authors.lastname: Salnikova
authors.affiliation: Terahertz Biomedicine Laboratory, Photonics and Optical Information Department, ITMO University, 49 Kronverksky Ave, St. Petersburg 197101, Russia.
authors.forename: Mikhail
authors.initials: M
authors.lastname: Khodzitsky
keywords: (170.0170) Medical optics and biotechnology; (170.3660) Light propagation in tissues