title: Methods of Screening-Purification and Antimicrobial Potentialities of Bacteriocin in Health Care.
abstract: BACKGROUND
  Bacteriocin have been tested as safe and effective alternative molecules over the currently used chemotherapeutic agents. Thus, being an important clinical significance, its screening and recovery methods along with its application are poorly described. Therefore, their screening, purification strategies and utilities must me extended. Thus, in this review, we, summarize potential application, various screening and purification methods used for recovery of bacteriocins.
  
  
  METHODS
  To complete this review, many reviews and previously published reports were studied. We, concentrated on review question and exclusion and inclusion criteria. The quality of content was evaluated by the quality the quality contents evaluation method. The standard method is used to describe the useful contents of available resources and appraised.
  
  
  RESULTS
  One hundred twenty research and review reports were used to complete this report. Sixty reports were used to make a collective information on screening and production of Bacteriocin Eighty two papers were used to explore the antimicrobial, therapeutic, diagnostic etc potentialities of bacteriocin in diverse field. The summarize form of data also presented in the form of tables and figures. This review describes the various methods and parameters that must be considered during the screening and purification methods. Moreover, the useful information is collected in regard represent it therapeutic potentialities in various fields for the welfare of human being.
  
  
  CONCLUSIONS
  The conclusion of this review presented the significance of a fundamental framework for planning to understanding the basic requirement needed for fast, cost effective screening and purification of bacteriocins. The summered area of their utilities also helpful to extend the research field of bacteriocin. Thus, this report would be useful not only to scale up the screening and production strategies faster at economical rate, but also provides a platform to extend the research field of bacteriocin in many ways.
authors.affiliation: Nanomedicine & Nanobiotechnology Lab, Department of Biosciences, Integral University, Kursi Road, Dasauli, Lucknow- 226026. India.
authors.forename: Varish
authors.initials: V
authors.lastname: Ahmad
authors.affiliation: Department of Health Information Management, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim. Saudi Arabia.
authors.forename: Qazi Mohammad Sajid
authors.initials: QMS
authors.lastname: Jamal
authors.affiliation: Department of Health Information Management, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim. Saudi Arabia.
authors.forename: Mughees Uddin
authors.initials: MU
authors.lastname: Siddiqui
authors.affiliation: King Abdullah Institute for Nanotechnology, King Saud University, P.O. Box 2455, Riyadh 11451. Saudi Arabia.
authors.forename: Arun K
authors.initials: AK
authors.lastname: Shukla
authors.affiliation: Department of Medical Laboratory, College of Applied Medical Sciences, Qassim University, Al Qassim. Saudi Arabia.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Alzohairy
authors.affiliation: Department of Medical Laboratory, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim. Saudi Arabia.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Al Karaawi
authors.affiliation: King Fahd Medical Research Center, King Abdulaziz University, P. O. Box 80216, Jeddah 21589. Saudi Arabia.
authors.forename: Mohammad Amjad
authors.initials: MA
authors.lastname: Kamal
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000145:classification / Q000493:pharmacokinetics / Q000494:pharmacology; D001430:Bacteriocins / Q000008:administration & dosage / Q000145:classification / Q000493:pharmacokinetics / Q000494:pharmacology; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents; D001430:Bacteriocins
keywords: Bacteriocin; antimicrobial; health care; purification; screening; therapeutics potentialities