title: Green Tea Consumption and the Risk of Liver Cancer: A Meta-Analysis.
abstract: Green tea is a commonly consumed beverage in Asia and has been suggested to have anticarcinogenic properties. To date, epidemiological evidence of the effect of green tea consumption on liver cancer risk remains ambiguous. The aim of this meta-analysis is to evaluate the association between green tea consumption and the risk of liver cancer. The summary relative risk for the highest consumption (≥5 cups/day) of green tea on liver cancer incidence compared with nondrinkers was 0.62 (95% confidence interval: 0.49-0.79). We also found a trend that the incidence of liver cancer was reduced with the increasing years of green tea intake (significance at >20 yr). A significant dose-response association was found between green tea drinking and liver cancer risk. The downward trend was most obvious when the consumption of green tea increased up to about 4 cups/day. The results showed that the increasing green tea intake may have a preventive effect against liver cancer.
authors.affiliation: a Department of Pharmacy , Shanghai Tenth People's Hospital, Tongji University School of Medicine , Shanghai , China.|b College of Pharmacy, Second Military Medical University , Shanghai , China.
authors.forename: Chen-Xu
authors.initials: CX
authors.lastname: Ni
authors.affiliation: c Laboratory of Stress Medicine , Faculty of Psychology and Mental Health, Second Military Medical University , Shanghai , China.
authors.forename: Hong
authors.initials: H
authors.lastname: Gong
authors.affiliation: d Department of Pharmacy , Dongfang Hospital , Shanghai , China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.affiliation: b College of Pharmacy, Second Military Medical University , Shanghai , China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Qi
authors.affiliation: c Laboratory of Stress Medicine , Faculty of Psychology and Mental Health, Second Military Medical University , Shanghai , China.
authors.forename: Chun-Lei
authors.initials: CL
authors.lastname: Jiang
authors.affiliation: b College of Pharmacy, Second Military Medical University , Shanghai , China.
authors.forename: Jun-Ping
authors.initials: JP
authors.lastname: Zhang
mesh_terms: D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology* / Q000517:prevention & control*; D012307:Risk Factors; D013662:Tea
chemical_list: D013662:Tea