title: Severe and extensive traumatic axonal injury following minor and indirect head trauma.
abstract: This study reports on a patient with mild traumatic brain injury (TBI) who showed severe and extensive traumatic axonal injury (TAI) of various neural tracts following minor and indirect head trauma, which was demonstrated by diffusion tensor tractography (DTT).
  
  
  
  A 26-year-old female patient suffered from indirect head trauma resulting from flexion-hyperextension injury after being hit from behind by a slowly moving car. At the time of head trauma, she felt tingling sensation on her four extremities; however, she did not experience loss of consciousness. At 5-day after onset, she began to experience tremor on the right leg and, subsequently, tremor had also developed in the left leg. At 8-days after onset, she could not even stand due to tremor of both legs and began to feel a tingling sensation on both legs. Since ~ 2 weeks after head trauma, myoclonus had developed mainly in the trunk. After 10-weeks after head trauma, when she started rehabilitation, she showed mild quadriparesis (4+/4+) with severe weakness of the proximal joint (shoulder/hip, 4-/4-), severe resting and intentional tremor, ataxic gait and severe myoclonus.
  
  
  
  Severe and extensive TAI of various neural tracts was demonstrated in a patient with mild TBI following minor and indirect head trauma, using DTT.
authors.affiliation: a Department of Physical Medicine and Rehabilitation , College of Medicine, Yeungnam University , Namku , Taegu , Republic of Korea.
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Jang
authors.affiliation: a Department of Physical Medicine and Rehabilitation , College of Medicine, Yeungnam University , Namku , Taegu , Republic of Korea.
authors.forename: Han Do
authors.initials: HD
authors.lastname: Lee
mesh_terms: D000070642:Brain Injuries, Traumatic / Q000000981:diagnostic imaging / Q000209:etiology*; D006259:Craniocerebral Trauma / Q000150:complications* / Q000000981:diagnostic imaging; D056324:Diffusion Tensor Imaging; D018450:Disease Progression; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D011712:Pyramidal Tracts / Q000000981:diagnostic imaging; D055815:Young Adult
keywords: Mild traumatic brain injury; diffusion tensor imaging; myoclonus; traumatic axonal injury; tremor