title: Practical Synthetic Procedures for the Iron-Catalyzed Intermolecular Olefin Aminohydroxylation Using Functionalized Hydroxylamines.
abstract: A set of practical synthetic procedures for the iron-catalyzed intermolecular olefin aminohydroxylation reactions in gram scale is reported. In these transformations, a bench-stable functionalized hydroxylamine is applied as the amination reagent. This method is compatible with a broad range of synthetically valuable olefins including those that are incompatible with the existing aminohydroxylation methods. It also provides valuable amino alcohol building blocks with regio- and stereo-chemical arrays that are complementary to known methods.
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors.forename: Cheng-Liang
authors.initials: CL
authors.lastname: Zhu
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors.forename: Deng-Fu
authors.initials: DF
authors.lastname: Lu
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Sears
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors.forename: Zhen-Xin
authors.initials: ZX
authors.lastname: Jia
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Xu
keywords: alkenes; amination; asymmetric catalysis; iron; oxidation