title: Exudative epidermitis of piglets caused by non-toxigenic Staphylococcus sciuri.
abstract: Infections with strains of Staphylococcus sciuri are a potential threat to animal and public health, and a cause for considerable concern. We isolated and identified S. sciuri as a pathogen from an acute outbreak of exudative epidermitis in piglets for further genetic identification using experimental infections. The results of this study showed that S. sciuri strain NJ1306 reproduced exudative epidermitis in experimentally infected 5-day-old piglets. The isolated bacteria also caused sudden death in BALB/c mice following intraperitoneal injection with 5×108CFU of the isolate. The data indicated that strain NJ1306 of S. sciuri was pathogenic to piglets and mice, and the study provided the first known report of clinical lung lesions and endocarditis in piglets due to S. sciuri.
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture·National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210014, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, 225009, China. Electronic address: llxnj@139.com.
authors.forename: Lixin
authors.initials: L
authors.lastname: Lu
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture·National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210014, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, 225009, China.
authors.forename: Kongwang
authors.initials: K
authors.lastname: He
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture·National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210014, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, 225009, China.
authors.forename: Yanxiu
authors.initials: Y
authors.lastname: Ni
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture·National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210014, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, 225009, China.
authors.forename: Zhengyu
authors.initials: Z
authors.lastname: Yu
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture·National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210014, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, 225009, China.
authors.forename: Aihua
authors.initials: A
authors.lastname: Mao
mesh_terms: D000818:Animals; D004196:Disease Outbreaks / Q000662:veterinary*; D004697:Endocarditis, Bacterial / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D004818:Epidermitis, Exudative, of Swine / Q000382:microbiology* / Q000473:pathology; D008168:Lung / Q000473:pathology; D008807:Mice, Inbred BALB C; D012867:Skin / Q000382:microbiology; D013203:Staphylococcal Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D013210:Staphylococcus / Q000302:isolation & purification / Q000502:physiology*; D013552:Swine
keywords: Experimental infection; Exudative epidermitis; Staphylococcus sciuri; Virulence-associated gene