title: Follicular thyroid carcinoma presenting with pathological fracture of the humerus at initial diagnosis.
abstract: Differentiated carcinomas of the thyroid gland usually have a good prognosis with prognosis often discussed in terms of 20 year survival. Nevertheless its 10-year-survival rate decreases when accompanied by distant metastasis. Follicular thyroid cancer (FTC) is the second most common thyroid cancer and usually presents with a solitary thyroid nodule with or without cervical lymphadenopathy. Distance metastasis at initial diagnosis is seldom observed with incidence range from 1 to 9%. In cases of bone metastasis, the incidence is only 2-3% and weight-bearing skeleton is preferentially affected. In our case, we present a patient with FTC that metastasized to the upper limb causing severe pain and pathological fracture at the initial presentation.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Leicester Royal Infirmary, Infirmary Square, LE1 5WW, UK dingyang@doctors.org.uk.
authors.forename: Wanding
authors.initials: W
authors.lastname: Yang
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Leicester Royal Infirmary, Infirmary Square, LE1 5WW, UK.
authors.forename: WaiSum
authors.initials: W
authors.lastname: Cho
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Leicester Royal Infirmary, Infirmary Square, LE1 5WW, UK.
authors.forename: Sudip
authors.initials: S
authors.lastname: Das
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Leicester Royal Infirmary, Infirmary Square, LE1 5WW, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Conboy