title: CRISPR control of virulence in Pseudomonas aeruginosa.
abstract: Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated genes (cas) are essential components of an adaptive immune system that protects bacteria and archaea from viral infection. Now a recent paper published in Cell Research suggests that the Type I-F immune system in Pseudomonas aeruginosa may also be involved in post-transcriptional regulation of virulence.
authors.affiliation: Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.
authors.forename: Blake
authors.initials: B
authors.lastname: Wiedenheft
authors.affiliation: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Bondy-Denomy
mesh_terms: D000818:Animals; D064113:CRISPR-Cas Systems; D064112:Clustered Regularly Interspaced Short Palindromic Repeats; D011549:Pseudomonas; D011550:Pseudomonas aeruginosa / Q000235:genetics*; D014774:Virulence