title: Ion mobility spectrometry as a fast analytical tool in benzalkonium chloride homologs determination.
abstract: A novel procedure is proposed for the determination by ion mobility spectrometry (IMS) of C12, C14and C16benzalkonium chloride (BAC) homologs. The proposed method requires minimum sample treatment and the measurement was made in less than one minute. A high sensitivity was obtained for BAC determination by IMS with limit of detection values from 37 to 69µgL-1. Accuracy of the proposed methodology was evaluated through the analysis of aqueous and alcoholic samples spiked with BAC at concentration levels from 0.002% to 20% (w/v), providing recovery values from 91% to 104%. BAC was determined in sanitary alcohols, nasal sprays, postharvest products, algaecides, and treated swimming pool water. Results obtained by the proposed IMS methodology were statistically comparable to those provided by a liquid chromatography-ultraviolet (LC-UV) reference methodology. The Green Certificate evaluation of the proposed IMS methodology provided 91 score points in the Eco-Scale as compared with 77 for LC-UV method.
authors.affiliation: Department of Analytical Chemistry, University of Valencia, Jeroni Muñoz Building, 50th Dr. Moliner St., 46100 Burjassot, Valencia, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Gallart-Mateu
authors.affiliation: Department of Analytical Chemistry, University of Valencia, Jeroni Muñoz Building, 50th Dr. Moliner St., 46100 Burjassot, Valencia, Spain. Electronic address: sergio.armenta@uv.es.
authors.forename: S
authors.initials: S
authors.lastname: Armenta
authors.affiliation: Department of Analytical Chemistry, University of Valencia, Jeroni Muñoz Building, 50th Dr. Moliner St., 46100 Burjassot, Valencia, Spain.
authors.forename: F A
authors.initials: FA
authors.lastname: Esteve-Turrillas
authors.affiliation: Department of Analytical Chemistry, University of Valencia, Jeroni Muñoz Building, 50th Dr. Moliner St., 46100 Burjassot, Valencia, Spain.
authors.forename: M
authors.initials: M
authors.lastname: de la Guardia
keywords: Benzalkonium chloride; Green Analytical Chemistry; Ion mobility spectrometry; Quality control