title: New bunya-like viruses: Highlighting their relations.
abstract: The standard virus classification scheme for arenaviruses and bunyaviruses shifted dramatically when several groups reported the detection and isolation of divergent groups of viruses in a variety of insect collections. Although these viral families can differ in terms of morphology, structure and genetics, recent findings indicate these viruses may have a shared evolutionary origin. To determine the phylogenetic relations among these families, we inferred phylogenetic trees using three methods. The Maximum Likelihood and Bayesian trees were rooted as suggested by the (molecular clock-rooted) BEAST tree. Our results highlight a noteworthy relation among these viral supergroups of different genome organizations. Our study suggests that the best scenario is the existence of at least three monophyletic supergroups, all of them well supported. The recent data indicate that these viruses are evolutionarily and genetically interconnected. While these supergroups appear to be closely related in our phylogenetic analysis, other viruses should be investigated in future research. In sum, our results also provide insights into the classification scheme, thereby providing a new perspective about the fundamental questions of family origins, diversity and genome evolution.
authors.affiliation: Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil; Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: guterres@ioc.fiocruz.br.
authors.forename: Alexandro
authors.initials: A
authors.lastname: Guterres
authors.affiliation: Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
authors.forename: Renata Carvalho
authors.initials: RC
authors.lastname: de Oliveira
authors.affiliation: Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
authors.forename: Jorlan
authors.initials: J
authors.lastname: Fernandes
authors.affiliation: Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
authors.forename: Elba Regina Sampaio
authors.initials: ER
authors.lastname: de Lemos
authors.affiliation: Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Carlos Guerra
authors.initials: CG
authors.lastname: Schrago
mesh_terms: D000818:Animals; D001499:Bayes Theorem; D005075:Biological Evolution; D002043:Bunyaviridae / Q000145:classification / Q000235:genetics*; D016679:Genome, Viral; D007313:Insecta / Q000821:virology; D016013:Likelihood Functions; D008322:Mammals / Q000821:virology; D010802:Phylogeny; D010944:Plants / Q000821:virology
keywords: Arenaviruses; Bunyavirus supergroup; Bunyaviruses; Evolutionary history; Orthobunyaviruses; Phleboviruses; Tospoviruses