title: The dynamics of HIV transmission in out of school young heterosexual men in South Africa: a systematic scoping review protocol.
abstract: In South Africa, gender inequality dominated by males and heterosexual HIV epidemic are associated with high HIV infection. Underlying epidemiological and social determinants driving HIV acquisition and transmission are critical to understand the extent and complexity of sexual networks as primary mechanisms through which HIV is likely to spread. The aim of the study is to provide an overview of empiric evidence that links the complex interaction of risk of HIV infection in men.
  
  
  
  We will conduct a systematic scoping review to identify, describe, and map literature on the dynamics of HIV infection in men, and we will determine the quality of the studies reporting on the dynamics of HIV infections in men. Primary research articles, published in peer-reviewed journals, review articles, and gray literature that address the research question, will be included. We will search PubMed, Web of Knowledge, Science Direct, EBSCOhost, Google Scholar, World Health Organization library, and UNAIDS database. Reference lists and existing networks such as government organizations and conferences will also be included to source relevant literature. Two independent reviewers will extract data in parallel from all relevant search engines, using specific inclusion and exclusion criteria. A thematic content analysis will be used to present the narrative account of the reviews, using NVivo version 10.
  
  
  
  We anticipate finding relevant literature on the dynamics of HIV transmission in South African men. Once summarized, data will be useful to guide future research.
  
  
  
  PROSPERO CRD42016039489.
authors.affiliation: Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa. Nonzwakazi.Ntombela@caprisa.org.|Centre for the AIDS Programme of Research in South Africa, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. Nonzwakazi.Ntombela@caprisa.org.
authors.forename: Nonzwakazi
authors.identifier: 0000-0002-1657-2893
authors.initials: N
authors.lastname: Ntombela
authors.affiliation: Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Tivani P
authors.initials: TP
authors.lastname: Mashamba-Thompson
authors.affiliation: Centre for the AIDS Programme of Research in South Africa, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Andile
authors.initials: A
authors.lastname: Mtshali
authors.affiliation: Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Anna
authors.initials: A
authors.lastname: Voce
authors.affiliation: Centre for the AIDS Programme of Research in South Africa, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Ayesha B M
authors.initials: AB
authors.lastname: Kharsany
mesh_terms: D015658:HIV Infections / Q000635:transmission*; D020010:Heterosexuality / Q000523:psychology*; D006801:Humans; D012725:Sexual Behavior; D013019:South Africa; D000098584:Scoping Reviews as Topic
keywords: HIV transmission; Heterosexual men; Sex behavior