title: Synthesis of palladium@gold nanoalloys/nitrogen and sulphur-functionalized multiple graphene aerogel for electrochemical detection of dopamine.
abstract: Integration of noble metal nanomaterials on graphene nanosheets potentially paves one way to improve their electronic, chemical and electrochemical properties. The study reported synthesis of palladium@gold nanoalloys/nitrogen and sulphur-functionalized multiple graphene aerogel composite (Pd@Au/N,S-MGA). The as-prepared composite offers a well-defined three-dimensional architecture with rich of mesopores. The Pd@Au nanoalloys were dispersed on the graphene framework networks and their active sites were fully exposed. The unique structure achieves to ultra high electron/ion conductivity, electrocatalytic activity and structural stability. The sensor based on the Pd@Au/N,S-MGA creates ultrasensitive electrochemical response towards dopamine due to significantly electrochemical synergy between Pd, Au and N,S-MGA. Its differential pulse voltammetric signal linearly increases with the increase of dopamine concentration in the range from 1.0 × 10-9M to 4.0 × 10-5M with the detection limit of 3.6 × 10-10M (S/N = 3). The analytical method provides the advantage of sensitivity, reproducibility, rapidity and long-term stability. It has been successfully applied in the detection of trace dopamine in biological samples. The study also opens a window on the electronic properties of graphene aerogel and metal nanomaterials as well their nanohybrids to meet needs of further applications as nanoelectronics in diagnosis, bioanalysis and catalysis.
authors.affiliation: School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Ruiyi
authors.initials: R
authors.lastname: Li
authors.affiliation: School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Yang
authors.affiliation: School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China; Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, Wuxi 214122, China. Electronic address: zaijunli@jiangnan.edu.cn.
authors.forename: Zaijun
authors.initials: Z
authors.lastname: Li
authors.affiliation: School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Zhiguo
authors.initials: Z
authors.lastname: Gu
authors.affiliation: School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Guangli
authors.initials: G
authors.lastname: Wang
authors.affiliation: School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Junkang
authors.initials: J
authors.lastname: Liu
mesh_terms: D015374:Biosensing Techniques; D004298:Dopamine / Q000032:analysis*; D055664:Electrochemical Techniques; D005782:Gels; D006046:Gold; D006108:Graphite; D053768:Metal Nanoparticles; D009584:Nitrogen; D010165:Palladium; D015203:Reproducibility of Results; D013455:Sulfur
chemical_list: D005782:Gels; D010165:Palladium; D013455:Sulfur; D006046:Gold; D006108:Graphite; D009584:Nitrogen; D004298:Dopamine
keywords: Detection; Dopamine; Electrochemical sensor; Nitrogen and sulphur-functionalized multiple graphene aerogel; Palladium@gold nanoalloys