title: Phylogenetic and pathogenic analysis of Mycoplasma Synoviae isolated from native chicken breeds in China.
abstract: Mycoplasma synoviae (M. synoviae) infection leads to serious economic losses in the world every year. Between 2013 and 2014, the infectious synovitis, caused by M. synoviae infection, occurred in native chickens in China and resulted in the loss of millions of chickens in Chinese poultry farms. However, there has been no data about phylogenetic and pathogenic analysis of Chinese M. synoviae isolates. In this study, a total of 110 M. synoviae strains were isolated from M. synoviae infected chickens. The isolates identified in the present study were classified into a new distinct subgroup based on analysis of the 5'-end vlhA sequences, tentatively termed the K group. In addition, though the pathogenicity was significantly different among isolates, there was no close relationship between pathogenicity and genotype for Chinese M. synoviae based on a pathogenic analysis of the 5'-end of the vlhA gene.
authors.affiliation: State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresourses, Guangxi University, Nanning, Guangxi, China.|Guangdong Enterprise Key Laboratory for Animal Health and Environmental Control, WENS Group Academy, Yunfu, Guangdong, China.
authors.forename: Shikai
authors.initials: S
authors.lastname: Sun
authors.affiliation: Guangdong Enterprise Key Laboratory for Animal Health and Environmental Control, WENS Group Academy, Yunfu, Guangdong, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Lin
authors.affiliation: State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
authors.forename: Junmei
authors.initials: J
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
authors.forename: Zhongqiang
authors.initials: Z
authors.lastname: Tian
authors.affiliation: College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
authors.forename: Yongchang
authors.initials: Y
authors.lastname: Cao
authors.affiliation: Guangdong Enterprise Key Laboratory for Animal Health and Environmental Control, WENS Group Academy, Yunfu, Guangdong, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Qin
authors.affiliation: State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresourses, Guangxi University, Nanning, Guangxi, China.
authors.forename: Tingrong
authors.initials: T
authors.lastname: Luo
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D002645:Chickens; D002681:China; D037102:Lectins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D009175:Mycoplasma Infections / Q000382:microbiology / Q000662:veterinary*; D045805:Mycoplasma synoviae / Q000145:classification / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology*; D011201:Poultry Diseases / Q000382:microbiology*; D016415:Sequence Alignment / Q000662:veterinary; D014774:Virulence
chemical_list: D001426:Bacterial Proteins; D037102:Lectins; C406455:VlhA protein, Mycoplasma synoviae
keywords: Chinese native chicken breeds; Mycoplasma synoviae; pathogenicity; phylogenetic analysis; vlhA