title: Individuals with dark eyes and hair exhibit higher pain sensitivity.
abstract: Emerging evidence suggests that some phenotypic features, such as eye or hair colour, might predict pain. We investigated if light and dark eye and hair colour would influence pain in 60 healthy subjects divided in groups of 15 according to their eye-hair colour and gender. Pressure pain thresholds (PPTs), cold pressor test (CPT), and quality of the perceived pain were assessed. Findings indicated that dark pigmentation phenotype is more sensitive in response to CPT.
authors.affiliation: a Department of Health Science and Technology , Aalborg University , Aalborg , Denmark.
authors.forename: Henrik
authors.initials: H
authors.lastname: Holmgaard
authors.affiliation: a Department of Health Science and Technology , Aalborg University , Aalborg , Denmark.
authors.forename: Eva Ørsnæs
authors.initials: EØ
authors.lastname: Hansen
authors.affiliation: a Department of Health Science and Technology , Aalborg University , Aalborg , Denmark.
authors.forename: Nhung Phuong Thi
authors.initials: NP
authors.lastname: Dong
authors.affiliation: a Department of Health Science and Technology , Aalborg University , Aalborg , Denmark.
authors.forename: Laila Brøns
authors.initials: LB
authors.lastname: Dixen
authors.affiliation: a Department of Health Science and Technology , Aalborg University , Aalborg , Denmark.
authors.forename: Gebbie Ann Rodriguez
authors.initials: GA
authors.lastname: Nielsen
authors.affiliation: a Department of Health Science and Technology , Aalborg University , Aalborg , Denmark.
authors.forename: Jeppe Nørgaard
authors.initials: JN
authors.lastname: Poulsen
authors.affiliation: a Department of Health Science and Technology , Aalborg University , Aalborg , Denmark.
authors.forename: Parisa
authors.initials: P
authors.lastname: Gazerani
mesh_terms: D000293:Adolescent; D000328:Adult; D005127:Eye Color; D005260:Female; D006200:Hair Color; D006801:Humans; D006930:Hyperalgesia / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement; D017288:Pain Threshold / Q000502:physiology*; D011312:Pressure; D018709:Statistics, Nonparametric; D055815:Young Adult
keywords: Pain; phenotype; pigmentation