title: Imaging Locally Advanced, Recurrent, and Metastatic Prostate Cancer: A Review.
abstract: OBJECTIVE
  Prostate cancer is the second leading cause of cancer deaths in US men. The course of prostate cancer is highly variable, and timely and accurate detection of clinically significant cancer is critical in positively affecting outcomes.
  
  
  METHODS
  Molecular imaging methods and magnetic resonance imaging (MRI) are the most promising new developments for prostate tumor visualization. While the benefits of MRI are many, positron emission tomography (PET) radiotracers are still available only as research tools.
  
  
  CONCLUSIONS
  The current research-based evidence on PET imaging has demonstrated encouraging potential in the initial diagnosis and detection of recurrence and metastases of prostate cancer.
authors.affiliation: Molecular Imaging Program, National Cancer Institute, National Institute of Health (NIH), Bethesda, Maryland.
authors.forename: Maria L
authors.initials: ML
authors.lastname: Lindenberg
authors.affiliation: Molecular Imaging Program, National Cancer Institute, National Institute of Health (NIH), Bethesda, Maryland.
authors.forename: Baris
authors.initials: B
authors.lastname: Turkbey
authors.affiliation: Molecular Imaging Program, National Cancer Institute, National Institute of Health (NIH), Bethesda, Maryland.
authors.forename: Esther
authors.initials: E
authors.lastname: Mena
authors.affiliation: Molecular Imaging Program, National Cancer Institute, National Institute of Health (NIH), Bethesda, Maryland.
authors.forename: Peter L
authors.initials: PL
authors.lastname: Choyke
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D057054:Molecular Imaging / Q000379:methods*; D060787:Neoplasm Grading; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology