title: Highly Stereoselective Gold-Catalyzed Coupling of Diazo Reagents and Fluorinated Enol Silyl Ethers to Tetrasubstituted Alkenes.
abstract: We report a highly stereoselective synthesis of all-carbon or fluorinated tetrasubstituted alkenes from diazo reagents and fluorinated enol silyl ethers, using C-F bond as a synthetic handle. Cationic AuIcatalysis plays a key role in this reaction. Remarkable fluorine effects on the reactivity and selectivity was also observed.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, East China Normal University, 3663N Zhongshan Road, Shanghai, 200062, China.
authors.forename: Fu-Min
authors.initials: FM
authors.lastname: Liao
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, East China Normal University, 3663N Zhongshan Road, Shanghai, 200062, China.
authors.forename: Zhong-Yan
authors.initials: ZY
authors.lastname: Cao
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, East China Normal University, 3663N Zhongshan Road, Shanghai, 200062, China.
authors.forename: Jin-Sheng
authors.initials: JS
authors.lastname: Yu
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, East China Normal University, 3663N Zhongshan Road, Shanghai, 200062, China.|State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Shanghai, 200032, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
keywords: coupling reactions; diazo reagents; fluorine effects; gold catalysis; olefination