title: An ESIPT-Based Fluorescent Probe for Hydrazine Detection in Aqueous Solution and its Application in Living Cells.
abstract: A new fluorescent probe based on "protection-deprotection" sequence and the excited-state intramolecular proton transfer (ESIPT) effect was designed and synthesized. The probe responds rapidly and high selectively toward hydrazine at room temperature, and exhibits a low detection limit of 0.016 μM (0.512 ppb), which is well below the safety level (10 ppb) as regulated by EPA. Moreover, it can be applied for the imaging of hydrazine in living cells.
authors.affiliation: College of Chemistry and Chemical Engineering, Xuchang University, Xuchang, 461000, China. juz1696@163.com.
authors.forename: Zhiyu
authors.initials: Z
authors.lastname: Ju
authors.affiliation: College of Chemistry and Chemical Engineering, Xuchang University, Xuchang, 461000, China.
authors.forename: Dapeng
authors.initials: D
authors.lastname: Li
authors.affiliation: Institute of Quality Standards and Testing Technology for Agro-Products, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
authors.forename: Di
authors.initials: D
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Chemical Engineering, Xuchang University, Xuchang, 461000, China.
authors.forename: Dandan
authors.initials: D
authors.lastname: Li
authors.affiliation: College of Chemistry and Chemical Engineering, Xuchang University, Xuchang, 461000, China.
authors.forename: Changzeng
authors.initials: C
authors.lastname: Wu
authors.affiliation: College of Chemistry and Chemical Engineering, Xuchang University, Xuchang, 461000, China. xuzhihong1980@yahoo.com.
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Xu
mesh_terms: D004938:Esophageal Neoplasms / Q000378:metabolism*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D006834:Hydrazines / Q000032:analysis*; D011522:Protons; D013050:Spectrometry, Fluorescence / Q000379:methods*; D014407:Tumor Cells, Cultured; D014867:Water / Q000032:analysis*
chemical_list: D005456:Fluorescent Dyes; D006834:Hydrazines; D011522:Protons; D014867:Water; C029424:hydrazine
keywords: Biological imaging; Excited state intramolecular proton transfer; Fluorescence; Hydrazine