title: Pathogens and epidemiologic feature of severe fever with thrombocytopenia syndrome in Hubei province, China.
abstract: To evaluate the aetiological agents and epidemiologic features of severe fever with thrombocytopenia syndrome (SFTS) in Hubei province, China, sera from patients were collected from January to December 2011. All cases occurred from April to December, and the epidemic peaked from May to August. The ages of patients ranged from 10 to 86 years (median=55years), and the incidence of SFTS increased with age. The female:male ratio of cases was 1.008:1, and 54.6% (77/141) and 1.4% (2/141) of the cases were confirmed by qPCR to be SFTSV and Hantavirus (HV) infection, respectively. No case of simultaneous infection with two or more pathogens was found. The research in this paper showed that some suspected SFTS cases are confused with HV infection due to similar symptoms. The analysis showed that the distribution of SFTSV has a marked regional aggregation in Hubei province.
authors.affiliation: Institute of Medical Virology, Wuhan University School of Basic Medical Sciences, Wuhan, 430072, China; Division for Viral Disease Detection, Hubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
authors.forename: Jianbo
authors.initials: J
authors.lastname: Zhan
authors.affiliation: College of Medicine, Wuhan university of Science and Technology, Wuhan, 430081, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Cheng
authors.affiliation: Division for Viral Disease Detection, Hubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Hu
authors.affiliation: Division for Viral Disease Detection, Hubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: Division for Viral Disease Detection, Hubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
authors.forename: Ruangang
authors.initials: R
authors.lastname: Pan
authors.affiliation: Division for Viral Disease Detection, Hubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Division for Viral Disease Detection, Hubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Zou
authors.affiliation: Division for Viral Disease Detection, Hubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China. Electronic address: zhanfx@163.com.
authors.forename: Faxian
authors.initials: F
authors.lastname: Zhan
authors.affiliation: Institute of Medical Virology, Wuhan University School of Basic Medical Sciences, Wuhan, 430072, China. Electronic address: dguo@whu.edu.cn.
authors.forename: Deyin
authors.initials: D
authors.lastname: Guo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002044:Bunyaviridae Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D002648:Child; D002681:China / Q000453:epidemiology; D062665:Epidemiological Monitoring; D005260:Female; D006476:Orthohantavirus / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016856:Phlebovirus / Q000235:genetics* / Q000302:isolation & purification; D012367:RNA, Viral / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D012367:RNA, Viral
keywords: Epidemiologic; Features; Pathogens; SFTS