title: In situ generation and reactions of p-(trifluoromethyl)benzyl electrophiles: an efficient access to p-(trifluoromethyl)benzyl compounds.
abstract: A new three-component reaction, namely condensation-anti-Michael addition-aromatization, enabling the construction of benzylic compounds is disclosed. This reaction can not only act as an alternative approach to regioselective Csp2-H trifluoromethylation of arenes through an "aromatic to be" strategy, but also provides a simple, convenient, step-economic, and practical strategy for the in situ generation of electrophilic p-(trifluoromethyl)benzyl species under extremely mild conditions.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024, China. panl948@nenu.edu.cn liuqun@nenu.edu.cn.
authors.forename: Jinhuan
authors.initials: J
authors.lastname: Dong
authors.forename: Shuang
authors.initials: S
authors.lastname: Xin
authors.forename: Yanqing
authors.initials: Y
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Pan
authors.forename: Qun
authors.initials: Q
authors.lastname: Liu