title: Trachyspic acid 19-butyl ester, a new inhibitor of Plk1 polo box domain-dependent recognition from uncharacterized fungus RKGS-F2684.
authors.affiliation: RIKEN Center for Sustainable Research Science, Chemical Biology Research Group, Saitama, Japan.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Nogawa
authors.affiliation: RIKEN Center for Sustainable Research Science, Chemical Biology Research Group, Saitama, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Ogita
authors.affiliation: RIKEN Center for Sustainable Research Science, Chemical Biology Research Group, Saitama, Japan.
authors.forename: Yushi
authors.initials: Y
authors.lastname: Futamura
authors.affiliation: Alcohol Research and Institute, OENON Holdings, Inc, Yamanashi, Japan.
authors.forename: Shigenori
authors.initials: S
authors.lastname: Negishi
authors.affiliation: RIKEN Center for Sustainable Research Science, Bio-Active Compounds Discovery Research Unit, Saitama, Japan.
authors.forename: Nobumoto
authors.initials: N
authors.lastname: Watanabe
authors.affiliation: RIKEN Center for Sustainable Research Science, Chemical Biology Research Group, Saitama, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Osada
mesh_terms: D018797:Cell Cycle Proteins / Q000037:antagonists & inhibitors*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005658:Fungi / Q000378:metabolism*; D057166:High-Throughput Screening Assays / Q000379:methods; D017346:Protein Serine-Threonine Kinases / Q000037:antagonists & inhibitors*; D011518:Proto-Oncogene Proteins / Q000037:antagonists & inhibitors*; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000097869:Polo-Like Kinase 1
chemical_list: D018797:Cell Cycle Proteins; D004791:Enzyme Inhibitors; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins; D013141:Spiro Compounds; D000097869:Polo-Like Kinase 1; C094346:trachyspic acid