title: Targeting Glioblastoma with CAR T Cells.
abstract: CAR T cells targeting IL13Rα2 proved effective against recurrent multifocal leptomeningeal glioblastoma, according to a case report. Direct delivery of the therapy into the cerebrospinal fluid was well tolerated, completely eliminating the patient's brain and spinal tumors for 7.5 months, during which the patient resumed his normal activities.
mesh_terms: D000328:Adult; D001932:Brain Neoplasms; D064987:Cell- and Tissue-Based Therapy; D005909:Glioblastoma; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011948:Receptors, Antigen, T-Cell; D000076962:Receptors, Chimeric Antigen; D013601:T-Lymphocytes; D023041:Xenograft Model Antitumor Assays
chemical_list: D011948:Receptors, Antigen, T-Cell; D000076962:Receptors, Chimeric Antigen