title: [Cost-effectiveness analysis on colorectal cancer screening program].
abstract: Objective:To evaluate the cost-effectiveness of colorectal cancer screening program in different age groups from the view of health economics.Methods:The screening compliance rates, detection rates in different age groups were calculated by using the data from colorectal cancer screening program in Jiashan county, Zhejiang province. The differences in indicator among age groups were analyzed withχ(2) test or trendχ(2) test. The ratios of cost to the number of case were calculated according to cost statistics.Results:The detection rates of immunochemical fecal occult blood test (iFOBT) positivity, advanced adenoma and colorectal cancer and early stage cancer increased with age, while the early diagnosis rates were negatively associated with age. After exclusion the younger counterpart, the cost-effectiveness of individuals aged >50 years could be reduced by 15%-30%.Conclusion:From health economic perspective, it is beneficial to start colorectal cancer screening at age of 50 years to improve the efficiency of the screening.
authors.affiliation: Department of Epidemiology, School of Public Health, Zhejiang University, Hangzhou 310058, China.
authors.forename: Q C
authors.initials: QC
authors.lastname: Huang
authors.affiliation: Department of Epidemiology, School of Public Health, Zhejiang University, Hangzhou 310058, China.
authors.forename: D
authors.initials: D
authors.lastname: Ye
authors.affiliation: Department of Epidemiology, School of Public Health, Zhejiang University, Hangzhou 310058, China.
authors.forename: X Y
authors.initials: XY
authors.lastname: Jiang
authors.affiliation: General Office, Jiashan Institute for Cancer Prevention and Treatment, Jiashan 314100, China.
authors.forename: Q L
authors.initials: QL
authors.lastname: Li
authors.affiliation: Registry Office, Jiashan Institute for Cancer Prevention and Treatment, Jiashan 314100, China.
authors.forename: K Y
authors.initials: KY
authors.lastname: Yao
authors.affiliation: Department of Epidemiology, School of Public Health, Zhejiang University, Hangzhou 310058, China.
authors.forename: J B
authors.initials: JB
authors.lastname: Wang
authors.affiliation: Department of Epidemiology, School of Public Health, Zhejiang University, Hangzhou 310058, China.
authors.forename: M J
authors.initials: MJ
authors.lastname: Jin
authors.affiliation: Department of Epidemiology, School of Public Health, Zhejiang University, Hangzhou 310058, China.
authors.forename: K
authors.initials: K
authors.lastname: Chen
mesh_terms: D000368:Aged; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000191:economics / Q000453:epidemiology / Q000517:prevention & control; D003362:Cost-Benefit Analysis; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000191:economics* / Q000379:methods; D008875:Middle Aged; D009780:Occult Blood; D010043:Outcome and Process Assessment, Health Care / Q000191:economics*; D015397:Program Evaluation
keywords: Colorectal cancer; Cost-effectiveness; Screening