title: mcr-1-Harboring Salmonella enterica Serovar Typhimurium Sequence Type 34 in Pigs, China.
abstract: We detected the mcr-1 gene in 21 (14.8%) Salmonella isolates from pigs at slaughter; 19 were serovar Typhimurium sequence type 34. The gene was located on IncHI2-like plasmids that also harbored IncF replicons and lacked a conjugative transfer region. These findings highlight the need to prevent further spread of colistin resistance in animals and humans.
authors.forename: Linxian
authors.initials: L
authors.lastname: Yi
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Yanling
authors.initials: Y
authors.lastname: Gao
authors.forename: Yiyun
authors.initials: Y
authors.lastname: Liu
authors.forename: Yohei
authors.initials: Y
authors.lastname: Doi
authors.forename: Renjie
authors.initials: R
authors.lastname: Wu
authors.forename: Zhenling
authors.initials: Z
authors.lastname: Zeng
authors.forename: Zisen
authors.initials: Z
authors.lastname: Liang
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Liu
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002681:China / Q000453:epidemiology; D024901:Drug Resistance, Multiple, Bacterial; D023061:Gene Order; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D012481:Salmonella Infections, Animal / Q000453:epidemiology* / Q000382:microbiology*; D012486:Salmonella typhimurium / Q000145:classification* / Q000187:drug effects / Q000235:genetics*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents
keywords: China; Salmonella enterica serovar Typhimurium ST34; antimicrobial resistance; bacteria; clonal spread; colistin; food safety; mcr-1 gene; pigs; sequence type; slaughter; zoonoses