title: Current Management of Low Risk Differentiated Thyroid Cancer and Papillary Microcarcinoma.
abstract: Each year, the proportion of thyroid cancer patients presenting with low risk disease is increasing. Moreover, the definition of low risk thyroid cancer is expanding and several histological subtypes beyond papillary microcarcinomas are now classified as low risk disease. This shift in the landscape of thyroid cancer presentation is forcing clinicians to critically re-evaluate whether or not traditional management paradigms that were effective in treating intermediate and high risk disease are applicable to these low risk patients. Here we review the definition of low risk disease, examine the various histological subtypes that are considered low risk in the 2015 American Thyroid Association guidelines for the management of thyroid nodules and thyroid cancer, and review our current approach to the management of these low risk tumours.
authors.affiliation: Endocrinology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
authors.forename: V D
authors.initials: VD
authors.lastname: Tarasova
authors.affiliation: Endocrinology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: tuttlem@mskcc.org.
authors.forename: R M
authors.initials: RM
authors.lastname: Tuttle
mesh_terms: D002291:Carcinoma, Papillary / Q000473:pathology*; D006801:Humans; D009367:Neoplasm Staging; D013961:Thyroid Gland / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000628:therapy; D013965:Thyroidectomy / Q000379:methods*
keywords: Low risk thyroid cancer; papillary microcarcinoma; staging