title: Benefits of Oxygen Saturation Targeting Trials: Oximeter Calibration Software Revision and Infant Saturations.
abstract: It has been reported in the 3 Benefits of Oxygen Saturation Targeting (BOOST-II) trials that changes in oximeter calibration software resulted in clearer separation between the oxygen saturations in the two trial target groups. A revised analysis of the published BOOST-II data does not support this conclusion.
authors.affiliation: Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.
authors.forename: Robin K
authors.initials: RK
authors.lastname: Whyte
authors.affiliation: Neonatal Trials Group, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Harvey
authors.initials: H
authors.lastname: Nelson
authors.affiliation: Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Robin S
authors.initials: RS
authors.lastname: Roberts
authors.affiliation: Division of Neonatology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.
authors.forename: Barbara
authors.initials: B
authors.lastname: Schmidt
mesh_terms: D002138:Calibration; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis*; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D010092:Oximetry / Q000295:instrumentation* / Q000379:methods; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption / Q000502:physiology*; D016032:Randomized Controlled Trials as Topic; D012680:Sensitivity and Specificity; D012984:Software
chemical_list: D010100:Oxygen
keywords: clinical trials; extremely low birth-weight infant; oxygen targets; pulse oximetry