title: An update on the 2014 Ebola outbreak in Western Africa.
abstract: The recent Ebola outbreak in Western Africa was the most devastating outbreak witnessed in recent times. There have been remarkable local and international efforts to control the crisis. Ebola Virus Disease is the focus of immense research activity. The progression of events in the region has been evolving swiftly and it is of paramount importance to the medical community to be acquainted with the situation. Over 28000 people were inflicted with the condition, over 11000 have died. Novel data has emerged regarding modes of transmission, providing rationale for recent flare-ups. Similarly, studies on survivors are elucidating the later stages of the disease recovery process. Novel techniques for diagnosis are also discussed. Finally, the current research regarding treatment and vaccine development is reviewed, particularly the implementation of rVSV-ZEBOV vaccination programs.
authors.affiliation: Department of Clinical Medicine, Education Division, Trinity College Dublin, The University of Dublin, Dublin, Ireland.
authors.forename: Haaris A
authors.initials: HA
authors.lastname: Shiwani
authors.affiliation: Department of Cardiology, The Adelaide and Meath Hospital Dublin, Incorporating the National Children Hospital, Tallaght, Dublin, 24, Ireland.
authors.forename: Rebabonye B
authors.initials: RB
authors.lastname: Pharithi
authors.affiliation: Department of Cardiology, The Adelaide and Meath Hospital Dublin, Incorporating the National Children Hospital, Tallaght, Dublin, 24, Ireland.
authors.forename: Barkat
authors.initials: B
authors.lastname: Khan
authors.affiliation: University of Ndjamena, Faculty of Medicine, Ndjamena, Chad.
authors.forename: Christian Binoun-A
authors.initials: CB
authors.lastname: Egom
authors.affiliation: International Clinical Research Center, St. Anne's University Hospital and Masaryk University, Brno, Czech Republic.
authors.forename: Peter
authors.initials: P
authors.lastname: Kruzliak
authors.affiliation: Department of Cardiology, The Adelaide and Meath Hospital Dublin, Incorporating the National Children Hospital, Tallaght, Dublin, 24, Ireland.
authors.forename: Vincent
authors.initials: V
authors.lastname: Maher
authors.affiliation: Department of Clinical Medicine, Education Division, Trinity College Dublin, The University of Dublin, Dublin, Ireland; Department of Cardiology, The Adelaide and Meath Hospital Dublin, Incorporating the National Children Hospital, Tallaght, Dublin, 24, Ireland; Egom Clinical and Translational Research Services, Dartmouth, NS, Canada. Electronic address: egomemmanuel@gmail.com.
authors.forename: Emmanuel Eroume-A
authors.initials: EE
authors.lastname: Egom
keywords: EBOV; Ebola virus disease; Ebola virus vaccination; Western Africa