title: Intramolecular Construction of Trifluoromethyl Group by the Palladium-Catalyzed Alkylation of 2,3,3-Trifluoroallylic Carbonates with Indoles.
abstract: The palladium-catalyzed alkylation reaction of 2,3,3-trifluoroallylic carbonates with indoles afforded a trifluoromethyl group possessing 3-substituted indole derivatives. The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit.
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Taisyun
authors.initials: T
authors.lastname: Hanakawa
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Isa
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Shin-Ichi
authors.initials: SI
authors.lastname: Isobe
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hoshino
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Biao
authors.initials: B
authors.lastname: Zhou
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Motoi
authors.identifier: 0000-0002-8341-6866
authors.initials: M
authors.lastname: Kawatsura