title: Green synthesized Co nanoparticles doped amino-graphene modified electrode and its application towards determination of baicalin.
abstract: The present paper reported an one-pot synthesis of Co nanoparticles doped amino-graphene nanocomposites (Co-amino-Gr), involving in situ generation of Co nanoparticles (NPs). The simultaneous reduction of graphene oxide (GO) and Co2+to produce Co-amino-Gr had been achieved under mild reaction conditions using an environmentally benign reducing agent, glycine. By combining the merits of amino-Gr and the Co NPs, a highly sensitive electrochemical sensor was erected to detect baicalin based on the Co-amino-Gr nanocomposites. Under optimum conditions, the response peak currents were linear related with baicalin concentrations in the range of 1.0×10-8-8.0×10-7molL-1with a lower detection limit of 5.0×10-9molL-1(S/N=3). Additionally, the proposed method was used to detect baicalin in the medicinal capsules with satisfactory results.
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Kai
authors.initials: K
authors.lastname: Sheng
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; Department of Environmental Engineering and Chemistry, Luoyang Institute of Science and Technology, Luoyang 471023, PR China.
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Huichao
authors.initials: H
authors.lastname: Li
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Lina
authors.initials: L
authors.lastname: Zou
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: yebx@zzu.edu.cn.
authors.forename: Baoxian
authors.initials: B
authors.lastname: Ye
mesh_terms: D002138:Calibration; D060326:Chemistry Techniques, Synthetic; D003035:Cobalt / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation*; D004566:Electrodes; D005419:Flavonoids / Q000032:analysis* / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D055772:Green Chemistry Technology; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000295:instrumentation*
chemical_list: D005419:Flavonoids; C038044:baicalin; D003035:Cobalt; D006108:Graphite
keywords: Amino-graphene; Baicalin; Co nanoparticles; Voltammetric sensor