title: Prognostic role of margin status in open and CO2laser cordectomy for T1a-T1b glottic cancer.
abstract: BACKGROUND
  Cordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer.
  
  
  OBJECTIVE
  The aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis-T1) treated with CO2laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results.
  
  
  METHODS
  Clinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed.
  
  
  RESULTS
  Margin status is related to recurrence rate in both groups (p<0.05) without significant differences between open and laser cordectomy (p>0.05). The 5 years overall survival and disease-free survival were respectively 90.48% and 85.71% in Group A; 88.14% and 86.44% in Group B (p>0.05). Lower tracheostomy rate, earlier recovery of swallowing function and shorter hospital stay were observed in Group A (p<0.05).
  
  
  CONCLUSIONS
  Margin status has a prognostic role in T1a-T1b glottic cancer. Transoral laser surgery showed similar oncologic results of open cordectomy, with better functional outcomes.
authors.affiliation: University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Landolfo
authors.affiliation: University of Turin, Surgical Sciences Department, 2nd ENT Division, Turin, Italy.
authors.forename: Carmine Fernando
authors.initials: CF
authors.lastname: Gervasio
authors.affiliation: University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy. Electronic address: giuseppe.riva84@gmail.com.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Riva
authors.affiliation: University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Garzaro
authors.affiliation: University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
authors.forename: Rita
authors.initials: R
authors.lastname: Audisio
authors.affiliation: University of Turin, Surgical Sciences Department, 1st ENT Division, Turin, Italy.
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Pecorari
authors.affiliation: University of Turin, Surgical Sciences Department, 2nd ENT Division, Turin, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Albera
keywords: Câncer glótico inicial; Disease free survival; Early glottic cancer; Estado de margem; Laryngeal neoplasms; Margin status; Neoplasias laríngeas; Overall survival; Sobrevida global; Sobrevida livre de doença