title: A rapid electrochemical monitoring platform for sensitive determination of thiamethoxam based on β-cyclodextrin-graphene composite.
abstract: A rapid monitoring platform for sensitive voltammetric detection of thiamethoxam residues is reported in the present study. A β-cyclodextrin-reduced graphene oxide composite was used as a reinforcing material in electrochemical determination of thiamethoxam. Compared with bare glassy carbon electrodes, the reduction peak currents of thiamethoxam at reduced graphene oxide/glassy carbon electrode and β-cyclodextrin-reduced graphene oxide/glassy carbon electrode were increased by 70- and 124-fold, respectively. The experimental conditions influencing voltammetric determination of thiamethoxam, such as the amount of β-cyclodextrin-reduced graphene oxide, solution pH, temperature, and accumulation time, were optimized. The reduction mechanism and binding affinity of this material is also discussed. Under optimal conditions, the reduction peak currents increased linearly between 0.5 µM and 16 µM concentration of thiamethoxam. The limit of detection was 0.27 µM on the basis of a signal-to-noise ratio of 3. When the proposed method was applied to brown rice in a recovery test, the recoveries were between 92.20% and 113.75%. The results were in good concordance with the high-performance liquid chromatography method. The proposed method therefore provides a promising and effective platform for sensitive and rapid determination of thiamethoxam. Environ Toxicol Chem 2017;36:1991-1997. © 2017 SETAC.
authors.affiliation: Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing, China.|Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: XingChen
authors.initials: X
authors.lastname: Zhai
authors.affiliation: Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing, China.|Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Gu
authors.affiliation: Department of Water Supply and Drainage Sciences and Engineering, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin, China.
authors.forename: GuoPeng
authors.initials: G
authors.lastname: Zhou
authors.affiliation: Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: HaiTian
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: ZhenYu
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: AiJun
authors.initials: A
authors.lastname: Dong
authors.affiliation: Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing, China.|Department of Food Sciences and Engineering, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
mesh_terms: D002244:Carbon / Q000737:chemistry; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods*; D006108:Graphite / Q000737:chemistry*; D057230:Limit of Detection; D000073943:Neonicotinoids; D009574:Nitro Compounds / Q000032:analysis*; D012275:Oryza / Q000737:chemistry; D010078:Oxazines / Q000032:analysis*; D010087:Oxides / Q000737:chemistry; D010573:Pesticide Residues / Q000032:analysis*; D012680:Sensitivity and Specificity; D059629:Signal-To-Noise Ratio; D000077922:Thiamethoxam; D013844:Thiazoles / Q000032:analysis*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D000073943:Neonicotinoids; D009574:Nitro Compounds; D010078:Oxazines; D010087:Oxides; D010573:Pesticide Residues; D013844:Thiazoles; D047392:beta-Cyclodextrins; D002244:Carbon; D000077922:Thiamethoxam; D006108:Graphite; C031215:betadex
keywords: Brown rice; Determination; Electrochemical sensor; Thiamethoxam; β-cyclodextrin-graphene composite