title: Case for diagnosis. Lichen myxedematosus.
abstract: Scleromyxedema or lichen myxedematosus is a rare papular mucinosis of chronic and progressive course and unknown etiology. It is commonly associated with monoclonal gammopathy and may show extracutaneous manifestations, affecting the heart, lung, kidney, and nerves. The diagnosis is based on four criteria: generalized papular and sclerodermoid lesions; mucin deposition, fibroblast proliferation, and fibrosis in the histopathology; monoclonal gammopathy; and no thyroid disorders. This article reports the case of a scleromyxedema patient with a recent history of acute myocardial infarction and monoclonal gammopathy.
authors.affiliation: Faculdade Evangélica do Paraná (Fepar) - Curitiba (PR), Brazil.
authors.forename: Priscila Regina Orso
authors.initials: PR
authors.lastname: Rebellato
authors.affiliation: Universidade Positivo (UP) - Curitiba (PR), Brazil.
authors.forename: Mauren Beatriz Frazon
authors.initials: MB
authors.lastname: Carbonar
authors.affiliation: Universidade Federal do Paraná (UFPR) - Curitiba (PR), Brazil.
authors.forename: Nicole Iasmin Magario
authors.initials: NI
authors.lastname: Tabuti
authors.affiliation: Faculdade Evangélica do Paraná (Fepar) - Curitiba (PR), Brazil.
authors.forename: Graziela Junges Crescente
authors.initials: GJ
authors.lastname: Rastelli
mesh_terms: D049109:Cell Proliferation; D020405:Dermis / Q000473:pathology*; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009077:Mucins; D053718:Scleromyxedema / Q000473:pathology*
chemical_list: D009077:Mucins