title: Prevalence of Bovine herpesvirus type 4 in aborting dairy cows.
abstract: Bovine herpesvirus type 4 (BHV-4) is related to many different conditions: infertility, postpartal metritis, vulvovaginitis, mastitis, encephalitis, calf pneumonia, keratoconjunctivitis, cutaneous lesions, digital dermatitis and abortion. In this study a retrospective PCR examination of 100 extracted DNA samples from aborting cows was performed in order to determine: prevalence of BHV-4 in abortive cattle, whether coinfections BHV-4 with other abortifacient pathogens are present in the same sample and to determine the month of gestation when BHV-4 associated abortions were detected. Out of 100 examined samples, the BHV-4 genome was detected in 21 samples (21%). In two samples we detected coinfection of BHV-4 with bovine viral diarrhea virus (BVDV) and in one with Neospora caninum. Most of the BHV-4-associated abortions were detected during the seventh month of gestation. It was concluded that an active BHV-4 infection was present among cows that aborted on the farms examined. The high prevalence of the BHV-4 genome in abortion material suggests that this virus may have cause the abortions. Further studies and examinations are needed to establish causative connection between presence of BHV-4 and abortion.
authors.forename: Đ
authors.initials: Đ
authors.lastname: Cvetojević
authors.forename: B
authors.initials: B
authors.lastname: Savić
authors.forename: V
authors.initials: V
authors.lastname: Milićević
authors.forename: B
authors.initials: B
authors.lastname: Kureljušić
authors.forename: N
authors.initials: N
authors.lastname: Jezdimirović
authors.forename: D
authors.initials: D
authors.lastname: Jakić-Dimić
authors.forename: M
authors.initials: M
authors.lastname: Pavlović
authors.forename: Lj
authors.initials: L
authors.lastname: Spalević
mesh_terms: D037881:Aborted Fetus / Q000821:virology; D000034:Abortion, Veterinary / Q000821:virology*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000821:virology*; D004279:DNA, Viral / Q000302:isolation & purification; D006566:Herpesviridae Infections / Q000662:veterinary* / Q000821:virology; D026021:Herpesvirus 4, Bovine / Q000302:isolation & purification*; D015995:Prevalence; D014412:Tumor Virus Infections / Q000662:veterinary* / Q000821:virology
chemical_list: D004279:DNA, Viral