title: Structures, biological activities, and industrial applications of the polysaccharides from Hericium erinaceus (Lion's Mane) mushroom: A review.
abstract: Hericium erinaceus (Bull.) Pers., also known as Yamabushitake, Houtou and Lion's Mane, is capable of fortifying the spleen and nourishing the stomach, tranquilizing the mind, and fighting cancer. Over the past decade, it has been demonstrated that H. erinaceus polysaccharides possess various promising bioactivities, including antitumor and immunomodulation, anti-gastric ulcer, neuroprotection and neuroregeneration, anti-oxidation and hepatoprotection, anti-hyperlipidemia, anti-hyperglycemia, anti-fatigue and anti-aging. The purpose of the present review is to provide systematically reorganized information on extraction and purification, structure characteristics, biological activities, and industrial applications of H. erinaceus polysaccharides to support their therapeutic potentials and sanitarian functions.
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China; Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China. Electronic address: hxrhist@163.com.
authors.forename: Xirui
authors.initials: X
authors.lastname: He
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China.
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Wang
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China.
authors.forename: Jiacheng
authors.initials: J
authors.lastname: Fang
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chang
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Ning
authors.initials: N
authors.lastname: Ning
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Hao
authors.initials: H
authors.lastname: Guo
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China. Electronic address: huanglhlab@163.com.
authors.forename: Linhong
authors.initials: L
authors.lastname: Huang
authors.affiliation: Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Huang
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China.
authors.forename: Zefeng
authors.initials: Z
authors.lastname: Zhao
mesh_terms: D000363:Agaricales / Q000737:chemistry* / Q000254:growth & development / Q000378:metabolism; D000818:Animals; D046508:Culture Techniques; D006801:Humans; D007221:Industry; D011134:Polysaccharides / Q000096:biosynthesis / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D011134:Polysaccharides
keywords: Hericium erinaceus; Industrial applications; Polysaccharides