title: Short-term and long-term follow-up of pulmonary function in patients with COPD after total laryngectomy: A prospective study.
abstract: There exists no standardized method for examining lung function in laryngectomized patients.
  
  
  
  We established a base plate adapter (BPA) system for patients after laryngectomy. In 10 patients with chronic obstructive pulmonary disease (COPD), we evaluated pulmonary function before laryngectomy, as well as 2 weeks and 3 months after laryngectomy.
  
  
  
  The BPA system was well tolerated and delivered reliable results comparable to measurements with a mouthpiece. The parameters forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and mean forced expiratory flow between 25% and 75% of forced vital capacity (MFEF25-75) changed in the early postoperative examinations (2 weeks postoperative), whereas MFEF25-75, FEF75, peak expiratory flow (PEF), and peak inspiratory flow (PIF)) showed differences from baseline in long-term follow-up (3 months postoperative).
  
  
  
  We provide a practicable method of lung function testing in laryngectomized patients with COPD that is essential to tailor inhalation therapy despite tracheotomy. Lung function measurements of laryngectomized patients with COPD should be performed under stable clinical conditions a few weeks after surgery. Guidelines of COPD might be complemented considering the subgroup of laryngectomized patients.
  
  
  
  4. Laryngoscope, 127:2045-2049, 2017.
authors.affiliation: Department III of Internal Medicine, University of Cologne, Cologne, Germany.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Schönwald
authors.affiliation: Department III of Internal Medicine, University of Cologne, Cologne, Germany.
authors.forename: Maria Isabel
authors.initials: MI
authors.lastname: Körber
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany.
authors.forename: Dirk
authors.initials: D
authors.lastname: Beutner
authors.affiliation: Department III of Internal Medicine, University of Cologne, Cologne, Germany.
authors.forename: Roman
authors.initials: R
authors.lastname: Pfister
authors.affiliation: Department III of Internal Medicine, University of Cologne, Cologne, Germany.
authors.forename: Konrad
authors.initials: K
authors.lastname: Frank
authors.affiliation: Department of Otorhinolaryngology, Jena University Hospital, Jena, Germany.
authors.forename: Orlando
authors.identifier: 0000-0001-9671-0784
authors.initials: O
authors.lastname: Guntinas-Lichius
authors.affiliation: Department III of Internal Medicine, University of Cologne, Cologne, Germany.
authors.forename: Guido
authors.initials: G
authors.lastname: Michels
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005540:Forced Expiratory Flow Rates; D005541:Forced Expiratory Volume; D006801:Humans; D007825:Laryngectomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology* / Q000601:surgery; D012129:Respiratory Function Tests / Q000295:instrumentation* / Q000379:methods; D013997:Time Factors; D014797:Vital Capacity
keywords: COPD; Spirometry; lung function; total laryngectomy