title: Metastatic Prostate Cancer Diagnosed by Bone Marrow Aspiration in an Elderly Man Not Undergoing PSA Screening.
abstract: Prostate cancer screening by PSA testing remains controversial, particularly in the elderly. Practice guidelines from most clinical societies suggest discontinuing PSA screening at age 70 while the USPSTF recommends against screening at any age. Recent reports have demonstrated an increased incidence of metastatic prostate cancer, with men aged 75 or older accounting for roughly half of those newly diagnosed at an incurable stage. We herein describe the case of an elderly gentleman with no history of prostate cancer screening who presented with anorexia and back pain of unclear etiology. Evaluation with bone marrow aspiration revealed a diagnosis of metastatic prostate cancer.
authors.affiliation: The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Ridwan
authors.initials: R
authors.lastname: Alam
authors.affiliation: The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Tosoian
authors.affiliation: Texas Oncology, Waco, TX, USA.
authors.forename: Ofobuike
authors.initials: O
authors.lastname: Okani
authors.affiliation: The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Ashley E
authors.initials: AE
authors.lastname: Ross
authors.affiliation: Pathologists Bio-Medical Laboratory, Department of Pathology, Baylor University Medical Center at Dallas, Dallas, TX, USA.
authors.forename: Milena
authors.initials: M
authors.lastname: Vuica-Ross
keywords: Metastasis; Older men; PSA; PSA, prostate-specific antigen; Prostate cancer; Screening; USPSTF, United States Preventive Services Task Force