title: HIV and hypogonadism: a new challenge for young-aged and middle-aged men on effective antiretroviral therapy.
abstract: Male hypogonadism is poorly defined in people living with HIV. Using a reliable free-testosterone assay, we examined the prevalence and risk factors of male hypogonadism among people living with HIV on effective antiretroviral therapy. Male hypogonadism was found in 12.4% of patients, twice the rate reported in the general population of the same age. Two risk thresholds, namely 5 years of antiretroviral therapy and 19% total body fat, may help to identify patients at risk.
authors.affiliation: aDepartment of Infectious Diseases, Bichat-Claude-Bernard Hospital, AP-HPbParis Diderot University, Sorbonne Paris Cité, PariscDepartment of Infectious Diseases, Tourcoing Hospital, TourcoingdLaboratory of Biochemistry, Lille Hospital, LilleeDepartment of Nuclear Medicine, Lille Hospital, LillefLaboratory of Virology, Lille Hospital, LillegParis-Saclay University, Paris-Sud University, UVSQ, CESP U1018, INSERMhDepartment of Internal Medicine, Bicêtre Hospital, AP-HPiEA 7327 Paris Descartes University, Paris, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Lachâtre
authors.forename: Armelle
authors.initials: A
authors.lastname: Pasquet
authors.forename: Faïza
authors.initials: F
authors.lastname: Ajana
authors.forename: Benoit
authors.initials: B
authors.lastname: Soudan
authors.forename: Georges
authors.initials: G
authors.lastname: Lion
authors.forename: Laurence
authors.initials: L
authors.lastname: Bocket
authors.forename: Pauline
authors.initials: P
authors.lastname: Cornavin
authors.forename: Eric
authors.initials: E
authors.lastname: Senneville
authors.forename: Faroudy
authors.initials: F
authors.lastname: Boufassa
authors.forename: Antoine
authors.initials: A
authors.lastname: Chéret
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007006:Hypogonadism / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors
chemical_list: D044966:Anti-Retroviral Agents