title: Lethal mechanisms in gastric volvulus.
abstract: A 55-year-old wheelchair-bound woman with severe cerebral palsy was found at autopsy to have marked distention of the stomach due to a volvulus. The stomach was viable, and filled with air and fluid and had pushed the left dome of the diaphragm upwards causing marked compression of the left lung with a mediastinal shift to the right (including the heart). There was no evidence of gastric perforation, ischaemic necrosis or peritonitis. Removal of the organ block revealed marked kyphoscoliosis. Histology confirmed the viability of the stomach and biochemistry showed no dehydration. Death in cases of acute gastric volvulus usually occurs because of compromise of the gastric blood supply resulting in ischaemic necrosis with distention from swallowed air and fluid resulting in perforation with lethal peritonitis. Hypovolaemic shock may also occur. However, the current case demonstrates an alternative lethal mechanism, that of respiratory compromise due to marked thoracic organ compression.
authors.affiliation: Discipline of Anatomy and Pathology, The University of Adelaide, Australia; Forensic Science SA, Adelaide, Australia.
authors.forename: Kimberley J
authors.initials: KJ
authors.lastname: Omond
authors.affiliation: Discipline of Anatomy and Pathology, The University of Adelaide, Australia; Forensic Science SA, Adelaide, Australia.
authors.forename: Roger W
authors.initials: RW
authors.lastname: Byard
mesh_terms: D001344:Autopsy; D002547:Cerebral Palsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007738:Kyphosis; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000209:etiology*; D012600:Scoliosis; D013277:Stomach Volvulus / Q000150:complications* / Q000473:pathology*
keywords: Gastric volvulus; cerebral palsy; death; kyphoscoliosis; respiratory compromise