title: Review of Decision-Making in Game Tasks in Elderly Participants with Alzheimer Disease and Mild Cognitive Impairment.
abstract: Changes in decision-making (DM) have recently been investigated in patients with Alzheimer disease (AD) or mild cognitive impairment (MCI). DM is highly relevant to everyday functioning and autonomy. It relies on several cognitive abilities, such as semantic and episodic memory, as well as aspects of executive functioning. We conducted a systematic review of DM in older adults with MCI and AD.
  
  
  
  Only 5 studies whose main objective was to evaluate the DM performance were selected. The results extracted indicated that DM in ambiguity and in at-risk situations are both impaired in probable AD patients. MCI patients have difficulty making advantageous decisions under ambiguity and at risk, similar to patients with probable AD but they are less impaired. Key Messages: DM deficits may be a predictor of cognitive impairment and conversion to dementia and its potential clinical value should be further explored in longitudinal studies involving direct comparison between MCI and AD patients.
authors.affiliation: Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
authors.forename: Alaise Silva Santos
authors.initials: AS
authors.lastname: de Siqueira
authors.forename: Juliana Emy
authors.initials: JE
authors.lastname: Yokomizo
authors.forename: Wilson
authors.initials: W
authors.lastname: Jacob-Filho
authors.forename: Mônica Sanches
authors.initials: MS
authors.lastname: Yassuda
authors.forename: Ivan
authors.initials: I
authors.lastname: Aprahamian
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000523:psychology*; D060825:Cognitive Dysfunction / Q000523:psychology*; D003657:Decision Making / Q000502:physiology*; D005717:Games, Experimental; D006801:Humans; D008875:Middle Aged; D011597:Psychomotor Performance