title: [Study on sweat gland regeneration induced by microenvironment of three-dimensional bioprinting].
abstract: Sweat glands are abundant in the body surface and essential for thermoregulation. Sweat glands fail to conduct self-repair in patients with large area of burn and trauma, and the body temperature of patients increases in hot climate, which may cause shock or even death. Now, co-culture system, reprogramming, and tissue engineering have made progresses in inducing sweat gland regeneration, but the inductive efficiency and duration need to be improved. Cellular microenvironment can regulate cell biological behavior, including cell migration and cell differentiation. This article reviews the studies of establishment of microenvironment in vitro by three-dimensional bioprinting technology to induce sweat gland regeneration.
authors.affiliation: Key Laboratory of Tissue Repair and Regeneration of PLA, the First Hospital Affiliated to General Hospital of PLA, Beijing 100048, China.
authors.forename: B
authors.initials: B
authors.lastname: Yao
authors.forename: J F
authors.initials: JF
authors.lastname: Xie
authors.forename: S
authors.initials: S
authors.lastname: Huang
authors.forename: X B
authors.initials: XB
authors.lastname: Fu
mesh_terms: D062028:Bioprinting; D002056:Burns / Q000628:therapy*; D002454:Cell Differentiation; D018920:Coculture Techniques; D006801:Humans; D066330:Printing, Three-Dimensional; D012038:Regeneration; D013234:Stem Cells / Q000166:cytology*; D013545:Sweat Glands / Q000502:physiology*; D023822:Tissue Engineering
keywords: Cellular microenvironment; Regeneration; Sweat glands; Three-dimensional bioprinting