title: Loading of the medial meniscus in the ACL deficient knee: A multibody computational study.
abstract: The menisci of the knee reduce tibiofemoral contact pressures and aid in knee lubrication and nourishment. Meniscal injury occurs in half of knees sustaining anterior cruciate ligament injury and the vast majority of tears in the medial meniscus transpire in the posterior horn region. In this study, computational multibody models of the knee were derived from medical images and passive leg motion for two female subjects. The models were validated against experimental measures available in the literature and then used to evaluate medial meniscus contact force and internal hoop tension. The models predicted that the loss of anterior cruciate ligament (ACL) constraint increased contact and hoop forces in the medial menisci by a factor of 4 when a 100N anterior tibial force was applied. Contact forces were concentrated in the posterior horn and hoop forces were also greater in this region. No differences were found in contact or hoop tension between the intact and ACL deficient (ACLd) knees when only a 5Nm external tibial torque was applied about the long axis of the tibia. Combining a 100N anterior tibial force and a 5Nm external tibial torque increased posterior horn contact and hoop forces, even in the intact knee. The results of this study show that the posterior horn region of the medial meniscus experiences higher contact forces and hoop tension, making this region more susceptible to injury, especially with the loss of anterior tibia motion constraint provided by the ACL. The contribution of the dMCL in constraining posterior medial meniscus motion, at the cost of higher posterior horn hoop tension, is also demonstrated.
authors.affiliation: University of Missouri, Department of Physical Therapy, Department of Orthopaedic Surgery, 801 Clark Hall, Columbia, MO 65211-4250, United States . Electronic address: guesstr@health.missouri.edu.
authors.forename: Trent M
authors.initials: TM
authors.lastname: Guess
authors.affiliation: University of Missouri, Department of Physical Therapy, Department of Orthopaedic Surgery, 801 Clark Hall, Columbia, MO 65211-4250, United States.
authors.forename: Swithin
authors.initials: S
authors.lastname: Razu
mesh_terms: D000328:Adult; D016118:Anterior Cruciate Ligament; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D005260:Female; D005269:Femur / Q000502:physiology; D006801:Humans; D008592:Menisci, Tibial / Q000502:physiology*; D008954:Models, Biological; D009068:Movement; D013977:Tibia / Q000502:physiology; D016474:Weight-Bearing; D055815:Young Adult
keywords: Anterior cruciate ligament; Computational biomechanics; Medial collateral ligament; Medial meniscus; Menisci