title: CD44v6-Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells.
abstract: CD44v6 peptide functionalized nanoparticlesare fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for developing novel multifunctional nanocarriers for therapeutic and/or diagnostic anticancer applications.
authors.affiliation: Institute of Toxicology and Genetics Karlsruhe Institute of Technology 76344 Karlsruhe Germany; Institute of Organic Chemistry University of Heidelberg 69120 Heidelberg Germany.
authors.forename: Linxian
authors.initials: L
authors.lastname: Li
authors.affiliation: Institute of Toxicology and Genetics Karlsruhe Institute of Technology 76344 Karlsruhe Germany.
authors.forename: Mark
authors.initials: M
authors.lastname: Schmitt
authors.affiliation: Institute of Toxicology and Genetics Karlsruhe Institute of Technology 76344 Karlsruhe Germany.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Matzke-Ogi
authors.affiliation: Institute of Biological Interfaces (IBG-2) Karlsruhe Institute of Technology 76344 Karlsruhe Germany.
authors.forename: Parvesh
authors.initials: P
authors.lastname: Wadhwani
authors.affiliation: Institute of Toxicology and Genetics Karlsruhe Institute of Technology 76344 Karlsruhe Germany.
authors.forename: Veronique
authors.initials: V
authors.lastname: Orian-Rousseau
authors.affiliation: Institute of Toxicology and Genetics Karlsruhe Institute of Technology 76344 Karlsruhe Germany; Department of Applied Physical Chemistry University of Heidelberg 69120 Heidelberg Germany.
authors.forename: Pavel A
authors.initials: PA
authors.lastname: Levkin
keywords: CD44v6; antimetastatic activity; quantum dots; tumor targeting; v6 peptide