title: Paradoxical insomnia in a patient taking zopiclone.
abstract: We present a case of a man aged 20 years who was diagnosed with a major depressive disorder and was started on escitalopram and zopiclone. The patient had a significant response to escitalopram except that he developed severe insomnia which dramatically resolved following discontinuation of zopiclone. The patient was recommenced on low dose of zopiclone and unfortunately redeveloped moderate insomnia. The patient was thoroughly investigated and zopiclone was determined to have paradoxically caused the insomnia.
authors.affiliation: Department of Psychiatry, University of Alberta Faculty of Medicine and Dentistry, Edmonton, Alberta, Canada.|Department of Young Adult, Alberta Hospital Edmonton, Edmonton, Alberta, Canada.
authors.forename: Adam
authors.initials: A
authors.lastname: Abba-Aji
authors.affiliation: Queen Elizabeth II Hospital, Grande Prairie, Alberta, Canada.
authors.forename: Prajjita
authors.initials: P
authors.lastname: Bardoloi
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D053961:Azabicyclo Compounds / Q000009:adverse effects*; D015283:Citalopram / Q000627:therapeutic use; D000069340:Deprescriptions; D003865:Major Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D008297:Male; D010879:Piperazines / Q000009:adverse effects*; D007319:Sleep Initiation and Maintenance Disorders / Q000139:chemically induced*; D055815:Young Adult
chemical_list: D000928:Antidepressive Agents; D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone; D015283:Citalopram