title: Neural regulation of immunity: molecular mechanisms and clinical translation.
abstract: Studies bridging neuroscience and immunology have identified neural pathways that regulate immunity and inflammation. Recent research using methodological advances in molecular genetics has improved our understanding of the neural control of immunity. Here we outline mechanistic insights, focusing on translational relevance and conceptual developments. We also summarize findings from recent clinical studies of bioelectronic neuromodulation in inflammatory and autoimmune diseases.
authors.affiliation: Center for Biomedical Science, The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, USA.|Center for Bioelectronic Medicine, The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, USA.
authors.forename: Valentin A
authors.initials: VA
authors.lastname: Pavlov
authors.affiliation: Center for Biomedical Science, The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, USA.|Center for Bioelectronic Medicine, The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, USA.
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Tracey
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000276:immunology*; D006801:Humans; D007109:Immunity / Q000502:physiology*; D007249:Inflammation / Q000276:immunology*; D009424:Nervous System Physiological Phenomena / Q000276:immunology*; D009434:Neural Pathways / Q000276:immunology*; D009488:Neurosciences / Q000379:methods