title: Preoperative and intraoperative continuous use of dexmedetomidine on hyperalgesia after patients' remifentanil anesthesia.
abstract: OBJECTIVE
  Analyze clinical use of dexmedetomidine to relieve prognosis of remifentanil anesthesia recovery and analyze intervention effect.
  
  
  METHODS
  Choose 3600 cases of cerebral functional area operation patients treated in different hospitals during June 2011 and December 2015 for general analysis, group the patients by considering relevant parting of anesthesia recovery by American Society of Anesthesiologists, and divide the patients into dexmedetomidine group and control group according to different use of drugs. The two groups of patients are anesthetized, patients' anesthesia wake-up time and wake-up success rate are recorded, and effect of two types of anesthesia wake-up way are compared.
  
  
  RESULTS
  There exists no significant statistical difference in wake-up success rate of the two groups of patients, wake-up time has small difference, but anesthesia recovery quality of dexmedetomidine group is higher, which is conducive to physical rehabilitation of patients and minimize the effects of anesthetics on patients.
  
  
  CONCLUSIONS
  In clinical surgery, after use of remifentanil anesthesia on patients, use of dexmedetomidine for anesthesia recovery can minimize adverse effects of drugs on patients and thus is worthy to be effectively promoted in clinics.
authors.affiliation: Department of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, China.
authors.forename: M
authors.initials: M
authors.lastname: Yang
authors.affiliation: Department of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, China.
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, China.
authors.forename: F
authors.initials: F
authors.lastname: Zhang
authors.affiliation: Department of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, China.
authors.forename: H
authors.initials: H
authors.lastname: Fang
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000009:adverse effects; D001279:Atracurium / Q000008:administration & dosage / Q000031:analogs & derivatives; D020927:Dexmedetomidine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D006930:Hyperalgesia / Q000150:complications*; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage; D010880:Piperidines / Q000008:administration & dosage* / Q000009:adverse effects; D011300:Preoperative Care; D000077208:Remifentanil; D016896:Treatment Outcome
chemical_list: D006993:Hypnotics and Sedatives; D009466:Neuromuscular Blocking Agents; D010880:Piperidines; D001279:Atracurium; D020927:Dexmedetomidine; D000077208:Remifentanil; C101584:cisatracurium