title: Manipulating the microbiome.
abstract: The application of molecular methods has provided a new picture of the colon microbial flora, or microbiome. The microbiome has been found to be a complex ecosystem with multiple influences on its human host. In renal medicine, interest has focused on the microbiome as a source of toxic waste chemicals and a stimulant to unwanted systemic inflammation. Early attempts to manipulate the microbiome have yielded limited benefit, but further research is strongly motivated.
authors.affiliation: Department of Medicine, VA Palo Alto Health Care System, Palo Alto, California, USA; Department of Medicine, Stanford University, Palo Alto, California, USA.
authors.forename: Tammy L
authors.initials: TL
authors.lastname: Sirich
authors.affiliation: Department of Medicine, VA Palo Alto Health Care System, Palo Alto, California, USA; Department of Medicine, Stanford University, Palo Alto, California, USA. Electronic address: twmeyer@stanford.edu.
authors.forename: Timothy W
authors.initials: TW
authors.lastname: Meyer
mesh_terms: D006801:Humans; D064307:Microbiota