title: Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses' Health Study 2.
abstract: We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, the Nurses' Health Study 2. We used logistic regression to calculate age- and multivariate-adjusted odds ratios to determine the risk of incident AA and vitiligo associated with AD diagnosed in or before 2009. A total of 87 406 and 87 447 participants were included in the AA and vitiligo analyses, respectively. A history of AD in 2009 was reported in 11% of participants. There were 147 incident cases of AA and 98 incident cases of vitiligo over 2 years of follow-up. AD was associated with increased risk of developing AA (OR 1.80, 95% CI 1.18-2.76) and vitiligo (OR 2.14, 95% CI 1.29-3.54) in multivariate models. In this study of US women, AD was associated with increased risk of incident vitiligo and AA in adulthood.
authors.affiliation: Department of Dermatology, Warren Alpert Medical School, Providence, RI, USA.|Department of Dermatology, Rhode Island Hospital, Providence, RI, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Drucker
authors.affiliation: Department of Dermatology, Warren Alpert Medical School, Providence, RI, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Thompson
authors.affiliation: Department of Dermatology, Warren Alpert Medical School, Providence, RI, USA.|Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.
authors.forename: W-Q
authors.initials: WQ
authors.lastname: Li
authors.affiliation: Department of Dermatology, Warren Alpert Medical School, Providence, RI, USA.|Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.|Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
authors.forename: E
authors.initials: E
authors.lastname: Cho
authors.affiliation: Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
authors.forename: T
authors.initials: T
authors.lastname: Li
authors.affiliation: Laboratory for Investigative Dermatology, Rockefeller University, New York, NY, USA.|Department of Dermatology and the Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: E
authors.initials: E
authors.lastname: Guttman-Yassky
authors.affiliation: Department of Dermatology, Warren Alpert Medical School, Providence, RI, USA.|Department of Dermatology, Rhode Island Hospital, Providence, RI, USA.|Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.|Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Qureshi
mesh_terms: D000506:Alopecia Areata / Q000453:epidemiology* / Q000209:etiology*; D003876:Dermatitis, Atopic / Q000150:complications* / Q000453:epidemiology*; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D009726:Nurses; D016017:Odds Ratio; D011159:Population Surveillance; D018570:Risk Assessment; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D014820:Vitiligo / Q000453:epidemiology* / Q000209:etiology*
keywords: alopecia areata; atopic dermatitis; comorbidities; epidemiology; vitiligo