title: [The differences in the estimation of depression severity by psychiatrists and patients during the combined treatment with agomelatine (a multicenter study "EMOTSIA")].
abstract: OBJECTIVE
  To compare the prognosis of depression severity estimated by the physician and by the patient based on the treatment outcome.
  
  
  METHODS
  One hundred and seven patients with depression were examined. Mental status was assessed with HАМ-D, SHAPS, CGI-S, CGI-I, PGI-S, PGI-I and VAS. A data analysis was performed.
  
  
  RESULTS
  There were differences in the estimation of depression severity by psychiatrists and patients. Moreover, the scores on HАМ-D and CGI-S were not consistent when assessed by psychiatrists. As the severity of depression decreased and patient's state improved during the treatment with agomelatine (valdoxan), the assessments of the changes by the psychiatrist and the patient became similar.
  
  
  CONCLUSIONS
  Agomelatine (valdoxan) is effective and tolerable in the treatment of depression of any severity. The differences between the psychiatrist's and patient's estimation of the depression severity at baseline using different psychometric scales can level the prognostic value of treatment outcome.
authors.affiliation: Russian University of People's Friendship Moscow, Russia.
authors.forename: V E
authors.initials: VE
authors.lastname: Medvedev
authors.affiliation: Ural State Medical University, Yekaterinburg, Russia.
authors.forename: K Yu
authors.initials: KY
authors.lastname: Retiunsky
authors.affiliation: Novosibirsk State Medical University, Novosibirsk, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Ovchinnikov
authors.affiliation: Razumovsky Saratov State Medical University, Saratov, Russia.
authors.forename: Yu B
authors.initials: YB
authors.lastname: Barylnik
authors.affiliation: Pirogov National Research Medical University, Moscow, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Shmilovich
authors.affiliation: Orenburg State Medical University, Orenburg, Russia.
authors.forename: E Yu
authors.initials: EY
authors.lastname: Antokhin
authors.affiliation: Omsk State Medical Academy, Omsk, Russia.
authors.forename: G M
authors.initials: GM
authors.lastname: Usov
authors.affiliation: Organizatsion, Methodical and Consultation Unit for and Psychiatry And Suicidology Public Health Department, Moscow, Russia.
authors.forename: R A
authors.initials: RA
authors.lastname: Cheremin
authors.affiliation: South Ural State Medical University, Chelyabinsk, Russia.
authors.forename: V M
authors.initials: VM
authors.lastname: Poletsky
authors.affiliation: Murmansk Regional Psychoneurological Dispensary, Murmansk, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Onegin
authors.affiliation: Pirogov National Research Medical University, Moscow, Russia.
authors.forename: I P
authors.initials: IP
authors.lastname: Kireeva
authors.affiliation: Russian University of People's Friendship Moscow, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Frolova
authors.affiliation: Razumovsky Saratov State Medical University, Saratov, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Filippova
authors.affiliation: Razumovsky Saratov State Medical University, Saratov, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Antonova
authors.affiliation: Razumovsky Saratov State Medical University, Saratov, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Deeva
authors.affiliation: Murmansk Regional Psychoneurological Dispensary, Murmansk, Russia.
authors.forename: D A
authors.initials: DA
authors.lastname: Onegina
mesh_terms: D000081:Acetamides / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis*; D006801:Humans; D010820:Physicians; D011569:Psychiatric Status Rating Scales; D011570:Psychiatry; D011594:Psychometrics; D057566:Self Report; D016896:Treatment Outcome; D009281:Naphthalenes
chemical_list: D000081:Acetamides; D000928:Antidepressive Agents; C084711:agomelatine; D009281:Naphthalenes