title: "Inherently Chiral" Ionic-Liquid Media: Effective Chiral Electroanalysis on Achiral Electrodes.
abstract: To achieve enantioselective electroanalysis either chiral electrodes or chiral media are needed. High enantiodiscrimination properties can be granted by the "inherent chirality" strategy of developing molecular materials in which the stereogenic element responsible for chirality coincides with the molecular portion responsible for their specific properties, an approach recently yielding outstanding performances as electrode surfaces. Inherently chiral ionic liquids (ICILs) have now been prepared starting from atropisomeric 3,3'-bicollidine, synthesized from inexpensive reagents, resolved into antipodes without need of chiral HPLC and converted into long-chain dialkyl salts with melting points below room temperature. Both the new ICILs and shorter family terms, solid at room temperature, employed as low-concentration additives in achiral ILs, afford impressive enantioselection for the enantiomers of different probes on achiral electrodes, regularly increasing with additive concentration.
authors.affiliation: CNR, Istituto di Scienze e Tecnologie Molecolari (ISTM), Via Golgi 19, 20133, Milano, Italy.
authors.forename: Simona
authors.identifier: 0000-0003-2263-0954
authors.initials: S
authors.lastname: Rizzo
authors.affiliation: Università degli Studi di Milano, Dipartimento di Chimica, Via Golgi 19, 20133, Milano, Italia.
authors.forename: Serena
authors.identifier: 0000-0002-1981-4659
authors.initials: S
authors.lastname: Arnaboldi
authors.affiliation: Università degli Studi di Milano, Dipartimento di Chimica, Via Golgi 19, 20133, Milano, Italia.
authors.forename: Voichita
authors.identifier: 0000-0002-9983-2717
authors.initials: V
authors.lastname: Mihali
authors.affiliation: Istituto Superiore di Sanità, Dipartimento del Farmaco, Viale Regina Elena 299, 00161, Roma, Italy.
authors.forename: Roberto
authors.identifier: 0000-0001-6346-1953
authors.initials: R
authors.lastname: Cirilli
authors.affiliation: CNR, Istituto di Scienze e Tecnologie Molecolari (ISTM), Via Golgi 19, 20133, Milano, Italy.
authors.forename: Alessandra
authors.identifier: 0000-0002-5020-5544
authors.initials: A
authors.lastname: Forni
authors.affiliation: Università degli Studi di Padova, Dipartimento. di Scienze Chimiche, Via Marzolo 1, 35131, Padova, Italy.
authors.forename: Armando
authors.identifier: 0000-0002-7665-7178
authors.initials: A
authors.lastname: Gennaro
authors.affiliation: Università degli Studi di Padova, Dipartimento. di Scienze Chimiche, Via Marzolo 1, 35131, Padova, Italy.
authors.forename: Abdirisak Ahmed
authors.identifier: 0000-0003-0966-1983
authors.initials: AA
authors.lastname: Isse
authors.affiliation: Università di Roma "La Sapienza", Dipartimento di Chimica e Tecnologie del Farmaco, Piazzale Aldo Moro 5, 00185, Roma, Italy.
authors.forename: Marco
authors.identifier: 0000-0003-4030-8205
authors.initials: M
authors.lastname: Pierini
authors.affiliation: Università degli Studi di Milano, Dipartimento di Chimica, Via Golgi 19, 20133, Milano, Italia.
authors.forename: Patrizia Romana
authors.identifier: 0000-0003-4063-1563
authors.initials: PR
authors.lastname: Mussini
authors.affiliation: Università degli Studi di Milano, Dipartimento di Chimica, Via Golgi 19, 20133, Milano, Italia.
authors.forename: Francesco
authors.identifier: 0000-0003-4965-8543
authors.initials: F
authors.lastname: Sannicolò
keywords: bicollidinium salts; chiral electroanalysis; chiral ionic liquids; enantiodiscrimination; inherent chirality