title: Sarcomatoid carcinoma of the common bile duct: A case report.
abstract: BACKGROUND
  Sarcomatoid carcinoma is an extremely rare lesion in the common bile duct (CBD).
  
  
  METHODS
  We present a case of sarcomatoid carcinoma of the distal CBD in a 51-year-old woman who presented with jaundice and abdominal pain. Whipple's operation was performed successfully. Microscopically, the tumor was a poorly differentiated carcinoma containing a component of sarcoma-like differentiation. The tumor cells displayed spindle-shaped nuclei with occasional mitotic figures. Cytokeratin (CK) 7, CK19, CK18, and pan-CK (AE1/AE3) staining was positive on immunohistochemistry. Vimentin and carcinoembryonic antigen (CEA) staining were also positive.
  
  
  METHODS
  Sarcomatoid carcinoma of the distal CBD.
  
  
  METHODS
  The patient received three cycles of chemotherapy after surgery.
  
  
  RESULTS
  The patient has experienced no adverse events in the 3 years post-surgery.
  
  
  CONCLUSIONS
  We present here a case report of sarcomatoid carcinoma of the distal CBD. The patient received chemotherapy after surgery, and was event-free for 3 years post-surgery, suggesting a relatively better prognosis, despite the infiltrative pattern of the tumor.
authors.affiliation: Department of Abdominal Surgical Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Department of Pathology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors.forename: Shuisheng
authors.initials: S
authors.lastname: Zhang
authors.forename: Jia
authors.initials: J
authors.lastname: Jia
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Bi
authors.forename: Qinglong
authors.initials: Q
authors.lastname: Jiang
authors.forename: Yajie
authors.initials: Y
authors.lastname: Zhao
authors.forename: Yingtai
authors.initials: Y
authors.lastname: Chen
authors.forename: Quan
authors.initials: Q
authors.lastname: Xu
authors.forename: Zhongmin
authors.initials: Z
authors.lastname: Lan
authors.forename: Jianwei
authors.initials: J
authors.lastname: Zhang
authors.forename: Zhihui
authors.initials: Z
authors.lastname: Zhang
authors.forename: Chengfeng
authors.initials: C
authors.lastname: Wang
mesh_terms: D002277:Carcinoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D003135:Common Bile Duct / Q000473:pathology*; D003138:Common Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D019160:Endosonography; D005260:Female; D006801:Humans; D008875:Middle Aged; D014057:Tomography, X-Ray Computed