title: (R)-Ketamine Shows Greater Potency and Longer Lasting Antidepressant Effects Than Its Metabolite (2R,6R)-Hydroxynorketamine.
authors.affiliation: Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba.
authors.forename: Chun
authors.initials: C
authors.lastname: Yang
authors.affiliation: Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba.
authors.forename: Youge
authors.initials: Y
authors.lastname: Qu
authors.affiliation: Taisho Pharmaceutical Co., Ltd. , Saitama, Japan.
authors.forename: Masahito
authors.initials: M
authors.lastname: Abe
authors.affiliation: Taisho Pharmaceutical Co., Ltd. , Saitama, Japan.
authors.forename: Dai
authors.initials: D
authors.lastname: Nozawa
authors.affiliation: Taisho Pharmaceutical Co., Ltd. , Saitama, Japan.
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Chaki
authors.affiliation: Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba. Electronic address: hashimoto@faculty.chiba-u.jp.
authors.forename: Kenji
authors.initials: K
authors.lastname: Hashimoto
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D003866:Depressive Disorder / Q000188:drug therapy*; D004195:Disease Models, Animal; D004291:Dominance-Subordination; D007249:Inflammation / Q000188:drug therapy; D007649:Ketamine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D008070:Lipopolysaccharides; D008297:Male; D008810:Mice, Inbred C57BL; D013237:Stereoisomerism; D013315:Stress, Psychological / Q000188:drug therapy; D013997:Time Factors
chemical_list: D000928:Antidepressive Agents; D008070:Lipopolysaccharides; D007649:Ketamine; C050654:6-hydroxynorketamine