title: Cyberinfrastructure for Open Science at the Montreal Neurological Institute.
abstract: Data sharing is becoming more of a requirement as technologies mature and as global research and communications diversify. As a result, researchers are looking for practical solutions, not only to enhance scientific collaborations, but also to acquire larger amounts of data, and to access specialized datasets. In many cases, the realities of data acquisition present a significant burden, therefore gaining access to public datasets allows for more robust analyses and broadly enriched data exploration. To answer this demand, the Montreal Neurological Institute has announced its commitment to Open Science, harnessing the power of making both clinical and research data available to the world (Owens, 2016a,b). As such, the LORIS and CBRAIN (Das et al., 2016) platforms have been tasked with the technical challenges specific to the institutional-level implementation of open data sharing, including: Comprehensive linking of multimodal data (phenotypic, clinical, neuroimaging, biobanking, and genomics, etc.)Secure database encryption, specifically designed for institutional and multi-project data sharing, ensuring subject confidentiality (using multi-tiered identifiers).Querying capabilities with multiple levels of single study and institutional permissions, allowing public data sharing for all consented and de-identified subject data.Configurable pipelines and flags to facilitate acquisition and analysis, as well as access to High Performance Computing clusters for rapid data processing and sharing of software tools.Robust Workflows and Quality Control mechanisms ensuring transparency and consistency in best practices.Long term storage (and web access) of data, reducing loss of institutional data assets.Enhanced web-based visualization of imaging, genomic, and phenotypic data, allowing for real-time viewing and manipulation of data from anywhere in the world.Numerous modules for data filtering, summary statistics, and personalized and configurable dashboards. Implementing the vision of Open Science at the Montreal Neurological Institute will be a concerted undertaking that seeks to facilitate data sharing for the global research community. Our goal is to utilize the years of experience in multi-site collaborative research infrastructure to implement the technical requirements to achieve this level of public data sharing in a practical yet robust manner, in support of accelerating scientific discovery.
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Samir
authors.initials: S
authors.lastname: Das
authors.affiliation: Department of Computer Science and Software Engineering, Concordia University Montreal, QC, Canada.
authors.forename: Tristan
authors.initials: T
authors.lastname: Glatard
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Christine
authors.initials: C
authors.lastname: Rogers
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: John
authors.initials: J
authors.lastname: Saigle
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Santiago
authors.initials: S
authors.lastname: Paiva
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Leigh
authors.initials: L
authors.lastname: MacIntyre
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Mouna
authors.initials: M
authors.lastname: Safi-Harab
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Marc-Etienne
authors.initials: ME
authors.lastname: Rousseau
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Jordan
authors.initials: J
authors.lastname: Stirling
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada; Department of Computer Science and Software Engineering, Concordia UniversityMontreal, QC, Canada.
authors.forename: Najmeh
authors.initials: N
authors.lastname: Khalili-Mahani
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: David
authors.initials: D
authors.lastname: MacFarlane
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Penelope
authors.initials: P
authors.lastname: Kostopoulos
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Pierre
authors.initials: P
authors.lastname: Rioux
authors.affiliation: Douglas Mental Health University Hospital Montreal, QC, Canada.
authors.forename: Cecile
authors.initials: C
authors.lastname: Madjar
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Xavier
authors.initials: X
authors.lastname: Lecours-Boucher
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Vanamala
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Reza
authors.initials: R
authors.lastname: Adalat
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Zia
authors.initials: Z
authors.lastname: Mohaddes
authors.affiliation: Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Vladimir S
authors.initials: VS
authors.lastname: Fonov
authors.affiliation: Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Milot
authors.affiliation: Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Ilana
authors.initials: I
authors.lastname: Leppert
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: Clotilde
authors.initials: C
authors.lastname: Degroot
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Durcan
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Tara
authors.initials: T
authors.lastname: Campbell
authors.affiliation: Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Moreau
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Alain
authors.initials: A
authors.lastname: Dagher
authors.affiliation: Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: D Louis
authors.initials: DL
authors.lastname: Collins
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: Jason
authors.initials: J
authors.lastname: Karamchandani
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: Amit
authors.initials: A
authors.lastname: Bar-Or
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: Edward A
authors.initials: EA
authors.lastname: Fon
authors.affiliation: Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Rick
authors.initials: R
authors.lastname: Hoge
authors.affiliation: Montreal Neurological InstituteMontreal, QC, Canada; McConnell Brain Imaging Centre, Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Baillet
authors.affiliation: Montreal Neurological Institute Montreal, QC, Canada.
authors.forename: Guy
authors.initials: G
authors.lastname: Rouleau
authors.affiliation: McGill Centre for Integrative Neuroscience, Montreal Neurological InstituteMontreal, QC, Canada; Montreal Neurological InstituteMontreal, QC, Canada.
authors.forename: Alan C
authors.initials: AC
authors.lastname: Evans
keywords: bids; big data; cyberinfrastructure; data sharing; neuroimaging; neuroscience; open science framework; workflow