title: Do anxiety and depression statuses differ in differentpolycystic ovary syndrome phenotypes?
abstract: OBJECTIVE
  To evaluate psychological parameters and health quality profiles in women with reproductive polycystic ovary syndrome (PCOS) phenotypes and age matched controls.
  
  
  METHODS
  The study groups included 101 women with PCOS (54 with the National Institutes of Health [NIH] phenotype and 47 with the non-NIH phenotype) and 49 healthy female controls. The participants completed anxiety and depression scales and four quality of life domains.
  
  
  RESULTS
  We identified the women with PCOS as having a 3.39 times increased risk for depression (subscale &ge; 7) and a 3.64 times increased risk for anxiety (subscale &ge; 10) compared to the controls. Both NIH and non-NIH phenotypes showed similar rates of depression (46.3% vs. 46.8%, respectively; P = 0.57) and anxiety (31.5% vs. 36.2%, respectively; P = 0.47). Regarding the quality of life scale, the women with NIH PCOS had significantly lower mental health scores compared to those with non-NIH PCOS (P = 0.03). Furthermore, while mental health scores were similar in the women with PCOS and the controls, physical health scores were significantly lower in the women with PCOS (P = 0.007).
  
  
  CONCLUSIONS
  Nearly half of the women with PCOS had higher depression scores and one third had higher anxiety scores. Thus, psychiatric evaluations appear necessary for PCOS patients in order to diagnose and treat clinical depression and anxiety.
authors.affiliation: Department of Reproductive Medicine and Infertility, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.
authors.forename: Derya
authors.initials: D
authors.lastname: Akdağ Cirik
authors.affiliation: Department of Reproductive Medicine and Infertility, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.
authors.forename: Berna
authors.initials: B
authors.lastname: Dilbaz
authors.affiliation: Department of Reproductive Medicine and Infertility, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.
authors.forename: Sezin
authors.initials: S
authors.lastname: Aksakal
authors.affiliation: Department of Psychiatry, Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Kotan
authors.affiliation: Department of Reproductive Medicine and Infertility, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.
authors.forename: Runa
authors.initials: R
authors.lastname: Özelçi
authors.affiliation: Department of Reproductive Medicine and Infertility, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Akpınar
authors.affiliation: Department of Reproductive Medicine and Infertility, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.
authors.forename: Leyla
authors.initials: L
authors.lastname: Mollamahmutoğlu
mesh_terms: D001007:Anxiety; D003863:Depression; D005260:Female; D006801:Humans; D010641:Phenotype; D011085:Polycystic Ovary Syndrome; D011788:Quality of Life
keywords: Anxiety; depression; phenotype; polycystic ovary syndrome; quality of life