title: [Selective laser trabeculoplasty: Effect of number of preoperative topical glaucoma medications on pressure lowering and success rate].
abstract: OBJECTIVE
  To evaluate the lowering of intraocular pressure (IOP) one year after SLT and to assess if differences are related to number of pre-SLT topical treatments in ocular hypertension (OHT) and primary open angle glaucoma (POAG) patients.
  
  
  METHODS
  Retrospective review of 106 eyes of 13 OHT and 93 POAG patients treated by SLT for insufficient IOP control, allergy, discomfort or non-compliance to glaucoma medications, excluding patients with less than 1 year of follow-up after SLT. IOP was measured by applanation before and at 1, 6 and 12 months after SLT.
  
  
  RESULTS
  Hundred and six eyes untreated (n=13), or treated with one (n=25), two (n=40) or three or more (n=28) glaucoma medications were included. Mean IOP decreased from 19.4±3.6mmHg preoperatively to 15.7±3.1mmHg at 12 months, which corresponds to an average decrease of 18.8%. At 1 year, 62.2% (n=66) were responders (IOP reduction≥3mmHg): 92.3% without medications (n=12), 68% with one (n=17), 57.5% with two (n=23) and 50% with three or more medications (n=14). Their average IOP decreased from 20.7±3.4 to 15.2±2.9mmHg (26.6%), respectively from 20.8±2.6 to 15.8±3.2 (25%) without medications, 20.6±3.2 to 14.9±3.7 (27.3%) with one, 20.8±4.1 to 15.5±3.3 (25.1%) with two and 20.7±3.2 to 14.4±2.4mmHg (29.7%) with three medications.
  
  
  CONCLUSIONS
  The number of responders seems to be greater in OHT and POAG patients without or with few glaucoma medications, but the IOP reduction seems to be similar regardless of the number of glaucoma medications.
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France. Electronic address: sambonnelbasely@hotmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Bonnel
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: J-R
authors.initials: JR
authors.lastname: Fenolland
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: A-F
authors.initials: AF
authors.lastname: Marill
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Gaillard
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Rosenberg
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: V
authors.initials: V
authors.lastname: Theillac
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Mazharian
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: J-M
authors.initials: JM
authors.lastname: Giraud
authors.affiliation: Hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Renard
mesh_terms: D000287:Administration, Topical; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D053685:Laser Therapy / Q000379:methods*; D009798:Ocular Hypertension / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery*; D011300:Preoperative Care / Q000379:methods; D057234:Preoperative Period; D012189:Retrospective Studies; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents
keywords: Glaucome primitif à angle ouvert; Hypertonie oculaire; Intraocular pressure; Ocular hypertension; Pression intraoculaire; Primary open angle glaucoma; Trabeculoplasty; Trabéculoplastie