title: A Centralized Report on Pediatric Japanese Encephalitis Cases from Beijing Children's Hospital, 2013.
abstract: Fifteen pediatric cases of suspected Japanese encephalitis (JE) were reported in Beijing Children's Hospital during the late summer of 2013. The clinical manifestations in most cases included high fever, seizures, and abnormal magnetic resonance imaging findings. Twelve of 15 cases were laboratory-confirmed as JE cases by pathogen identification. Epidemiological investigations showed that five of the 12 laboratory-confirmed patients had an incomplete JE vaccination history. Follow-up investigations after discharge indicated that seven laboratory-confirmed JE patients without JE vaccinations had relatively poor prognoses, with an average Modified Rankin Scale (MRS) score of 2.6 when compared with the other five laboratory-confirmed, JE-vaccinated patients with an average MRS score of 0.5. The observation of pediatric JE cases among those with a history of JE vaccination warrants further attention.
authors.affiliation: Neurology Department, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
authors.forename: Jiu Wei
authors.initials: JW
authors.lastname: Li
authors.affiliation: Department of Viral Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Xiao Yan
authors.initials: XY
authors.lastname: Gao
authors.affiliation: Neurology Department, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Viral Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Shi Hong
authors.initials: SH
authors.lastname: Fu
authors.affiliation: Department of Polio, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Xiao Juan
authors.initials: XJ
authors.lastname: Tan
authors.affiliation: Department of Viral Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Yu Xi
authors.initials: YX
authors.lastname: Cao
authors.affiliation: Neurology Department, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
authors.forename: Wei Hua
authors.initials: WH
authors.lastname: Zhang
authors.affiliation: National Immunization Programme, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Zun Dong
authors.initials: ZD
authors.lastname: Yin
authors.affiliation: Department of Viral Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: He
authors.affiliation: National Immunization Programme, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Yi Xing
authors.initials: YX
authors.lastname: Li
authors.affiliation: Department of Viral Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Guo Dong
authors.initials: GD
authors.lastname: Liang
authors.affiliation: Department of Polio, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Wen Bo
authors.initials: WB
authors.lastname: Xu
authors.affiliation: Neurology Department, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing 100045, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Fang
authors.affiliation: Department of Viral Encephalitis, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory for Infectious Disease Prevention and Control (SKLID), Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Huan Yu
authors.initials: HY
authors.lastname: Wang
mesh_terms: D000068476:Beijing / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004664:Encephalitis Virus, Japanese / Q000502:physiology; D004672:Encephalitis, Japanese / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D005260:Female; D006801:Humans; D022321:Japanese Encephalitis Vaccines / Q000008:administration & dosage*; D008297:Male; D011379:Prognosis
chemical_list: D022321:Japanese Encephalitis Vaccines
keywords: Japanese encephalitis; Pediatric; Prognoses