title: Activity of LPO Processes in Women with Polycystic Ovarian Syndrome and Infertility.
abstract: Specific features of LPO processes and antioxidant defense were studied in patients with polycystic ovarian syndrome (PCOS) and infertility. Changes in LPO processes in patients with PCOS were compensatory, which manifested in increased α-tocopherol and retinol concentrations and moderate decrease in superoxide dismutase activity. Intensification of prooxidant processes was found in the group of patients with infertility without PCOS. The observed changes necessitate differentiated approach to the treatment of these patients.
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: L I
authors.initials: LI
authors.lastname: Kolesnikova
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: S I
authors.initials: SI
authors.lastname: Kolesnikov
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia. marina_darenskaya@inbox.ru.
authors.forename: M A
authors.initials: MA
authors.lastname: Darenskaya
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: L A
authors.initials: LA
authors.lastname: Grebenkina
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: O A
authors.initials: OA
authors.lastname: Nikitina
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: L M
authors.initials: LM
authors.lastname: Lazareva
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: L V
authors.initials: LV
authors.lastname: Suturina
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: I N
authors.initials: IN
authors.lastname: Danusevich
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: E B
authors.initials: EB
authors.lastname: Druzhinina
authors.affiliation: Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Semendyaev
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D019803:Glutathione Disulfide / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000175:diagnosis / Q000473:pathology; D015227:Lipid Peroxidation; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000175:diagnosis / Q000473:pathology; D013482:Superoxide Dismutase / Q000097:blood; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014801:Vitamin A / Q000097:blood; D024502:alpha-Tocopherol / Q000097:blood
chemical_list: D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances; D014801:Vitamin A; D013482:Superoxide Dismutase; D024502:alpha-Tocopherol; D019803:Glutathione Disulfide
keywords: adaptation; antioxidant defense; lipid peroxidation; polycystic ovarian syndrome