title: Steroid-induced glaucoma in the pediatric population.
abstract: Steroid medications may cause elevation of intraocular pressure, sometimes with permanent damage to the optic nerve. These therapies, via various routes of administration, are commonly prescribed for children, but the potential sequelae of elevated intraocular pressure and glaucomatous optic nerve damage can be even more severe and devastating in children than in adults. This review discusses the pathophysiology and potential risk factors, including the impact of intraocular pressure elevation via the different common routes of administration of steroids, clinical evaluation, and management of steroid response and steroid-induced glaucoma in children.
authors.affiliation: Ratner Children's Eye Center at the Shiley Eye Institute, University of California San Diego, La Jolla, California.
authors.forename: Brenda
authors.initials: B
authors.lastname: Nuyen
authors.affiliation: Shiley Eye Institute, University of California San Diego, La Jolla, California.
authors.forename: Robert N
authors.initials: RN
authors.lastname: Weinreb
authors.affiliation: Ratner Children's Eye Center at the Shiley Eye Institute, University of California San Diego, La Jolla, California. Electronic address: srobbins@ucsd.edu.
authors.forename: Shira L
authors.initials: SL
authors.lastname: Robbins
mesh_terms: D002648:Child; D002675:Child, Preschool; D005901:Glaucoma / Q000139:chemically induced* / Q000503:physiopathology; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007429:Intraocular Pressure / Q000187:drug effects* / Q000502:physiology; D012307:Risk Factors; D014129:Trabecular Meshwork / Q000187:drug effects / Q000503:physiopathology; D014792:Visual Acuity / Q000187:drug effects; D014794:Visual Fields / Q000187:drug effects
chemical_list: D005938:Glucocorticoids