title: Spontaneous rupture of hepatic epithelioid hemangioendothelioma: A case report.
abstract: Hepatic epithelioid hemangioendothelioma (HEH) is a rare tumor of vascular endothelial origin. Spontaneous rupture of HEH is a life-threatening complication and is extremely rare. HEH has variable malignant potential, and the clinical diagnosis remains challenging. Here we report a case of HEH with spontaneous rupture. A 44-year-old man presented with constant cutting pains over the right upper abdomen after eating. He had hemoptysis 11 d previously. Diagnostic abdominal puncture demonstrated active bleeding. Chest and abdominal computer tomography scan showed multiple ground-glass nodules over the lungs, multiple low-density intrahepatic nodules and massive hemorrhage. Transcatheter arterial embolization and exploratory laparotomy were performed and subsequent immunohistochemical examination confirmed a diagnosis of HEH.
authors.affiliation: Jun-Wu Yang, Yong Li, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao, Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
authors.forename: Jun-Wu
authors.initials: JW
authors.lastname: Yang
authors.affiliation: Jun-Wu Yang, Yong Li, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao, Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.affiliation: Jun-Wu Yang, Yong Li, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao, Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Xie
authors.affiliation: Jun-Wu Yang, Yong Li, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao, Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Dong
authors.affiliation: Jun-Wu Yang, Yong Li, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao, Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
authors.forename: Xian-Tong
authors.initials: XT
authors.lastname: Cao
authors.affiliation: Jun-Wu Yang, Yong Li, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao, Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Xiao
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D004621:Embolization, Therapeutic / Q000379:methods*; D018323:Hemangioendothelioma, Epithelioid / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008175:Lung Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000556:secondary; D008297:Male; D019152:Paracentesis; D035583:Rare Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D012422:Rupture, Spontaneous / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor
keywords: Hepatic epithelioid hemangioendothelioma; Spontaneous rupture