title: Advances in Myeloid-Like Cell Origins and Functions in the Model Organism Drosophila melanogaster.
abstract: Drosophila has long served as a valuable model for deciphering many biological processes, including immune responses. Indeed, the genetic tractability of this organism is particularly suited for large-scale analyses. Studies performed during the last 3 decades have proven that the signaling pathways that regulate the innate immune response are conserved between Drosophila and mammals. This review summarizes the recent advances on Drosophila hematopoiesis and immune cellular responses, with a particular emphasis on phagocytosis.
authors.affiliation: Laboratoire de Génétique de la drosophile et virulence microbienne, UR. EGFEM, Faculté des Sciences, Université Saint-Joseph de Beyrouth, B.P. 17-5208 Mar Mikhaël Beyrouth 1104 2020, Liban.
authors.forename: Laure
authors.initials: L
authors.lastname: El Chamy
authors.affiliation: Université de Strasbourg, UPR 9022 du CNRS, Institut de Biologie Moléculaire et Cellulaire, Strasbourg Cedex 67084, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Matt
authors.affiliation: Université de Strasbourg, UPR 9022 du CNRS, Institut de Biologie Moléculaire et Cellulaire, Strasbourg Cedex 67084, France.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Reichhart
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D004331:Drosophila melanogaster / Q000502:physiology*; D006410:Hematopoiesis; D007113:Immunity, Innate; D022423:Myeloid Cells / Q000502:physiology*; D010587:Phagocytosis