title: Genome Analysis of the Carbapenem- and Colistin-Resistant Escherichia coli Isolate NRZ14408 Reveals Horizontal Gene Transfer Pathways towards Panresistance and Enhanced Virulence.
authors.affiliation: Institute of Medical Microbiology, Justus Liebig University Giessen, and German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Giessen, Germany.
authors.forename: Linda
authors.initials: L
authors.lastname: Falgenhauer
authors.affiliation: Institute of Medical Microbiology, Justus Liebig University Giessen, and German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Giessen, Germany.
authors.forename: Hiren
authors.initials: H
authors.lastname: Ghosh
authors.affiliation: Institute of Medical Microbiology, Justus Liebig University Giessen, and German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Giessen, Germany.
authors.forename: Swapnil
authors.initials: S
authors.lastname: Doijad
authors.affiliation: Institute of Medical Microbiology, Justus Liebig University Giessen, and German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Giessen, Germany.
authors.forename: Yancheng
authors.initials: Y
authors.lastname: Yao
authors.affiliation: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, and German Center for Infection Research (DZIF), Partner site Hannover-Braunschweig, Braunschweig, Germany.
authors.forename: Boyke
authors.initials: B
authors.lastname: Bunk
authors.affiliation: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, and German Center for Infection Research (DZIF), Partner site Hannover-Braunschweig, Braunschweig, Germany.
authors.forename: Cathrin
authors.initials: C
authors.lastname: Spröer
authors.affiliation: Department of Medical Microbiology, Ruhr University, Bochum, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Kaase
authors.affiliation: Institute of Bioinformatics and Systems Biology, Justus Liebig University Giessen, Giessen, Germany.
authors.forename: Rolf
authors.initials: R
authors.lastname: Hilker
authors.affiliation: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, and German Center for Infection Research (DZIF), Partner site Hannover-Braunschweig, Braunschweig, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: Overmann
authors.affiliation: Institute of Medical Microbiology, Justus Liebig University Giessen, and German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Giessen, Germany.
authors.forename: Can
authors.initials: C
authors.lastname: Imirzalioglu
authors.affiliation: Institute of Medical Microbiology, Justus Liebig University Giessen, and German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, Giessen, Germany Trinad.chakraborty@mikrobio.med.uni-giessen.de.
authors.forename: Trinad
authors.initials: T
authors.lastname: Chakraborty
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015780:Carbapenems / Q000494:pharmacology*; D003091:Colistin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D022761:Gene Transfer, Horizontal / Q000235:genetics*; D016680:Genome, Bacterial / Q000235:genetics; D006801:Humans; D010957:Plasmids / Q000235:genetics; D014774:Virulence / Q000235:genetics; D000073336:Whole Genome Sequencing
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems; D003091:Colistin
keywords: Escherichia coli; carbapenem resistance; colistin resistance; mcr-1; multidrug resistance; plasmid-mediated resistance