title: Progressive Bilateral Vertebral Artery Dissection in a Case of Osteogenesis Imperfecta.
abstract: A 32-year-old woman with osteogenesis imperfecta (OI) was admitted to the hospital because of a right-sided occipital headache and facial paresthesia. She was diagnosed with lateral medullary syndrome due to right vertebral artery (VA) dissection. She was treated conservatively without antithrombotic therapy. She developed subarachnoid hemorrhage because of contralateral VA dissection 18 days later. This clinical course may reflect the underlying weakness of the vessel wall in OI. In patients with OI, occlusion of a unilateral VA could cause dissection and subsequent rupture of the contralateral VA. Early surgical treatment for lesions of the VA is required in such cases.
authors.affiliation: Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan. Electronic address: yujik@saitama-med.ac.jp.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kato
authors.affiliation: Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
authors.forename: Harumitsu
authors.initials: H
authors.lastname: Nagoya
authors.affiliation: Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Abe
authors.affiliation: Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hayashi
authors.affiliation: Department of Pathology, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
authors.forename: Masanori
authors.initials: M
authors.lastname: Yasuda
authors.affiliation: Department of Diagnostic Radiology, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Uchino
authors.affiliation: Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Tanahashi
authors.affiliation: Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Takao
mesh_terms: D000328:Adult; D038524:Diffusion Magnetic Resonance Imaging; D005192:Family Health; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D014854:Lateral Medullary Syndrome / Q000000981:diagnostic imaging / Q000209:etiology; D018810:Magnetic Resonance Angiography; D010013:Osteogenesis Imperfecta / Q000150:complications* / Q000000981:diagnostic imaging; D015898:Tomography Scanners, X-Ray Computed; D020217:Vertebral Artery Dissection / Q000150:complications* / Q000000981:diagnostic imaging
keywords: Osteogenesis imperfecta; bilateral vertebral artery dissection; lateral medullary syndrome; subarachnoid hemorrhage