title: Antibacterial efficacy of AH Plus and AH26 sealers mixed with amoxicillin, triple antibiotic paste and nanosilver.
abstract: Background.Elimination of bacteria from the root canal system is one of the aims of endodontic treatment; hence the incorporation of antibiotics into sealers can increase their antimicrobial efficacy. The aim of the present study was to determine the in vitro antimicrobial effects of AH26 and AH Plus sealers mixed with amoxicillin, triple antibiotic paste and nanosilver onEnterococcus faecalis.Methods.In this experiment, amoxicillin, triple antibiotic paste and nanosilver powder were added at 10% of the total sealer weight to AH26 and AH Plus sealers and then cultured freshly or after 1, 3, and 7 days with suspension of E. faecalis for 24 hours. The zones of growth inhibition forE. faecaliswere evaluated in each group.Results.Incorporation of nanosilver did not increase antibacterial effects of the sealers. Sealers combined with amoxicillin exhibited the highest antibacterial efficacy in fresh condition. In the set specimens, the results demonstrated that the mixture of sealers and triple antibiotic pastes exhibited the greatest antibacterial efficacy.Conclusion.Amoxicillin and triple antibiotic paste significantly improved the antibacterial properties of AH Plus and AH26 sealers. Such properties decreased with time, but the use of sealer-amoxicillin/triple paste combination was still superior to using sealers alone or in combination with nanosilver.
authors.affiliation: Department of Endodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Kangarlou
authors.affiliation: Private Dental Practice, Tehran, Iran.
authors.forename: Rojin
authors.initials: R
authors.lastname: Neshandar
authors.affiliation: Private Dental Practice, Tehran, Iran.
authors.forename: Negin
authors.initials: N
authors.lastname: Matini
authors.affiliation: Department of Endodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Omid
authors.initials: O
authors.lastname: Dianat
keywords: Antibacterial; Enterococcus faecalis; agar diffusion test; antibiotic; root canal sealer