title: Parsimonious blood use and lower transfusion triggers: What is the evidence?
abstract: Evidence supports a parsimonious approach to blood use for managing anemia, contrasting with the long-standing practice of blood transfusion targeting arbitrary hemoglobin levels. Hemodilution studies have demonstrated that humans can tolerate anemia. The cumulative data have confirmed and validated the safety of a conservative approach to transfusion. This has translated into formal national guidelines for blood transfusion as well as patient safety and quality markers supporting blood management stewardship to minimize unnecessary use of blood products.
authors.affiliation: Department of Hospital Medicine and Department of Pediatric Hospital Medicine, Cleveland Clinic, Cleveland, OH, USA. auronm@ccf.org.|Associate Professor of Medicine and Pediatrics, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Moises
authors.initials: M
authors.lastname: Auron
authors.affiliation: Staff Physician, Department of Pulmonary and Critical Care, MetroHealth Medical Center, Cleveland, OH, USA.
authors.forename: Marina Y
authors.initials: MY
authors.lastname: Duran Castillo
authors.affiliation: Chief, Department of Medicine, Hartford Hospital, Hartford, CT, USA.
authors.forename: Ajay
authors.initials: A
authors.lastname: Kumar
mesh_terms: D000740:Anemia / Q000628:therapy*; D001803:Blood Transfusion / Q000592:standards*; D000072700:Conservative Treatment / Q000379:methods / Q000592:standards*; D006438:Hemodilution / Q000379:methods / Q000592:standards; D006801:Humans