title: Herbal Extracts That Reduce Ocular Oxidative Stress May Enhance Attentive Performance in Humans.
abstract: We used herbal extracts in this study to investigate the effects of blue-light-induced oxidative stress on subjects' attentive performance, which is also associated with work performance. We employed an attention network test (ANT) to measure the subjects' work performance indirectly and used herbal extracts to reduce ocular oxidative stress. Thirty-two subjects participated in either an experimental group (wearing glasses containing herbal extracts) or a control group (wearing glasses without herbal extracts). During the ANT experiment, we collected electroencephalography (EEG) and electrooculography (EOG) data and measured button responses. In addition, electrocardiogram (ECG) data were collected before and after the experiments. The EOG results showed that the experimental group exhibited a reduced number of eye blinks per second during the experiment and faster button responses with a smaller variation than did the control group; this group also showed relatively more sustained tension in their ECG results. In the EEG analysis, the experimental group had significantly greater cognitive processing, with larger P300 and parietal 2-6 Hz activity, an orienting effect with neural processing of frontal area, high beta activity in the occipital area, and an alpha and beta recovery process after the button response. We concluded that reducing blue-light-induced oxidative stress with herbal extracts may be associated with reducing the number of eye blinks and enhancing attentive performance.
authors.affiliation: School of Information and Communications, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
authors.forename: Hohyun
authors.initials: H
authors.lastname: Cho
authors.affiliation: School of Information and Communications, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
authors.forename: Moonyoung
authors.initials: M
authors.lastname: Kwon
authors.affiliation: School of Information and Communications, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
authors.forename: Hyojung
authors.initials: H
authors.lastname: Jang
authors.affiliation: Department of Dermatology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea.
authors.forename: Jee-Bum
authors.initials: JB
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea.
authors.forename: Kyung Chul
authors.initials: KC
authors.lastname: Yoon
authors.affiliation: School of Information and Communications, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.
authors.forename: Sung Chan
authors.identifier: 0000-0001-5357-4436
authors.initials: SC
authors.lastname: Jun
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000494:pharmacology*; D001288:Attention / Q000187:drug effects*; D001767:Blinking / Q000187:drug effects*; D004585:Electrooculography; D005074:Evoked Potentials, Visual / Q000187:drug effects; D005133:Eye Movements / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D009010:Monte Carlo Method; D018384:Oxidative Stress / Q000187:drug effects*; D010775:Photic Stimulation; D010936:Plant Extracts / Q000494:pharmacology*; D011930:Reaction Time / Q000187:drug effects; D012815:Signal Processing, Computer-Assisted; D055815:Young Adult
chemical_list: D000975:Antioxidants; D010936:Plant Extracts