title: Oxidative decarbonylative coupling of aliphatic aldehydes with methacryloyl benzamides to generate isoquinoline-1,3(2H,4H)-diones.
abstract: Alkyl-substituted isoquinoline-1,3(2H,4H)-diones were prepared by decarbonylative coupling of N-alkyl-N-methacryloylbenzamides and aliphatic aldehydes under metal-free conditions. The reaction undergoes subsequent decarbonylation, radical addition and cyclization processes with aliphatic aldehydes as the cheap and abundant alkyl radical source. This procedure offers a complementary approach to the convenient generation of alkyl-substituted isoquinoline-1,3(2H,4H)-diones.
authors.affiliation: School of Chemical & Environmental Engineering, Jiangsu University of Technology, Changzhou 213001, P. R. China.
authors.forename: Changduo
authors.initials: C
authors.lastname: Pan
authors.affiliation: School of Chemical & Environmental Engineering, Jiangsu University of Technology, Changzhou 213001, P. R. China.
authors.forename: Chaoyue
authors.initials: C
authors.lastname: Chen
authors.affiliation: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou 213164, P. R. China. panchangduo@jsut.edu.cn yujintao@cczu.edu.cn.
authors.forename: Jin-Tao
authors.identifier: http://orcid.org/0000-0002-0264-9407
authors.initials: JT
authors.lastname: Yu