title: [Down syndrome and heart block secondary to neonatal lupus].
abstract: In Down syndrome, so far, has not been reported it's association with congenital heart block, this entity is rare and occurred in only 1% of mothers who have systemic lupus erythematosus, the presence of anti-Ro antibodies cross the placenta presenting neonatal lupus with skin lesions and congenital heart block, bradycardia, which is why we describe the following case. This is a new male end product of asymptomatic young mother, but serological birth with stigmata of Down syndrome, birth presents congenital bradycardia rare manifestation abnormalities, but common in children of mothers with lupus are initiated study protocol, realizing you including laboratory tests and immunological studies cabinet as electrocardiogram and echocardiogram, which gave tone to take the mother immunological studies, being positive antiRo. We concluded that the risk of heart block in a patient with Down syndrome is the same as for the general population.
authors.affiliation: Departamento de Cardiología Pediátrica, Hospital General Regional 36, Instituto Mexicano del Seguro Social, Puebla, Puebla, México. carla_illana@hotmail.com.
authors.forename: Carla Lucila
authors.initials: CL
authors.lastname: Illana-Bravo
authors.forename: Socorro
authors.initials: S
authors.lastname: Méndez-Martínez
authors.forename: María Enriqueta
authors.initials: ME
authors.lastname: Juan-Martínez
mesh_terms: D004314:Down Syndrome / Q000150:complications / Q000175:diagnosis*; D006327:Heart Block / Q000150:complications / Q000151:congenital* / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000151:congenital* / Q000175:diagnosis; D008297:Male
keywords: Down syndrome; Heart block; Lupus