title: Echocardiographic assessment of long-term hemodynamic characteristics of mechanical mitral valve prostheses with different mitral valvular diseases.
abstract: Mitral stenosis (MS) and mitral insufficiency (MI) have different pre-operative hemodynamic characteristics. However, it is unclear if there are differences in long-term echocardiographic characteristics of MS and MI patients after mechanical mitral valve replacement. This study is to compare long-term echocardiographic results of mechanical mitral valve prostheses between MS and MI patients. From January 2003 to January 2009, a total of 199 consecutive patients were recruited in this study. Patients were classified as group MS (n = 123) and MI (n = 76) according to the manifestation of mitral valvular disease. The mean age for patients was 50.1 ± 10.5 years and follow-up time was 7.2 ± 2.0 years. The MS after operation were more likely to experience atrial fibrillation (p = 0.002). The New York Heart Association (NYHA) class in MI showed a greater improvement (p = 0.006) than in MS. The left ventricular end-diastolic dimension (LVEDD) (p = 0.010) and stroke volume (SV) (p = 0.000) in MI were still larger than that in MS patients. These differences did not disappear with time after operation. The long-term echocardiographic results of mechanical mitral valve prostheses between MS and MI patients are significantly different. Over a long-term follow up, MI patients still have a larger LVEDD and SV than MS, and associated with a greater improvement of NYHA class.
authors.affiliation: Department of Cardiovascular Surgery, Henan Province People's Hospital, Zhengzhou, Henan Province, People's Republic of China.|Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610000, People's Republic of China.
authors.forename: Xiliang
authors.initials: X
authors.lastname: Zhu
authors.affiliation: West China School of Medicine, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Hong
authors.initials: H
authors.lastname: Tang
authors.affiliation: Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610000, People's Republic of China. xiaoxijun91@163.com.
authors.forename: Xijun
authors.initials: X
authors.lastname: Xiao
mesh_terms: D001281:Atrial Fibrillation / Q000150:complications / Q000503:physiopathology; D001807:Blood Vessel Prosthesis; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000473:pathology* / Q000503:physiopathology*; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D008946:Mitral Valve Stenosis / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D011182:Postoperative Care; D011300:Preoperative Care
keywords: Echocardiography; Hemodynamic characteristics; Mitral valve replacement; Mitral valvular disease