title: Primary adenosquamous carcinoma of the liver: a case report.
abstract: Adenosquamous carcinoma of the liver is a rare variant of cholangiocarcinoma. It is known to be a highly aggressive tumor with a poor prognosis, but its pathogenesis remains unclear owing to limited data in the literature. We report a case of 56-year-old woman who presented with a 1-week history of epigastric pain. Magnetic resonance imaging revealed a 6.5-cm ill-defined mass with low signal intensity in the left lobe of the liver, which was suspicious of cholangiocarcinoma. The patient underwent left hemihepatectomy. Microscopically, the tumor consisted of malignant glandular and squamous components and staged as pT2aN1. Despite postoperative chemoradiation, the patient had recurrence 8 months after surgery.
authors.affiliation: Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
authors.forename: Kyung Han
authors.initials: KH
authors.lastname: Nam
authors.affiliation: Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
authors.forename: Ji Yeon
authors.initials: JY
authors.lastname: Kim
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D018196:Carcinoma, Adenosquamous / Q000000981:diagnostic imaging / Q000473:pathology*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D005260:Female; D042882:Gallstones / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D016717:Sphincterotomy, Endoscopic; D014057:Tomography, X-Ray Computed
keywords: Adenosquamous carcinoma; Cholangiocarcinoma; Liver; Pathology