title: Studies on alterations of clinical and hemato-biochemical parameters before and after treatment in calves naturally infected with theileriosis.
abstract: OBJECTIVE
  The aim was to determine hemato-biochemical alterations and to determine the better treatment of theileriosis in naturally infected calves.
  
  
  METHODS
  A total of 74 Holstein crossbred calves below 6 months of age, of either sex were included for present investigation in Bikaner. Based on the clinical examinations and laboratory results, 20 calves included for hemato-biochemical studies (before and after treatment) and divided into two groups (having 10 calves each).
  
  
  RESULTS
  The clinical examination of these calves revealed weakness, ticks infestations, high fever above 104°F, pronounced swelling of prescapular, prefemoral, parotid lymph nodes, loss of elasticity of skin, anemia, lacrimal discharges, pulpy cornea, tachycardia, and dyspnea. There was highly significant decrease (p<0.01) in hemoglobin, total erythrocyte count, packed cell volume and total leukocyte count, serum glucose, total protein, globulin and albumin level and highly significant increase in aspartate aminotransferase and alanine aminotransferase level as compared to healthy control animals in Group I and II. The animals of Group II treated with buparvaquone along with single blood transfusion shows better recovery then animals of Group I treated with bupavaqone and hematinic.
  
  
  CONCLUSIONS
  Significant changes were found in hemato-biochemical parameters in theileria affected calves before treatment as compare to healthy control calves. Significant improvement was observed in hemato-biochemical parameters in buparvaquone and single blood transfusion treated calves as compare to another group, so it is concluded that buparvaquone and single blood transfusion is better combination for treatment of theileriosis.
authors.affiliation: Department of Clinical Veterinary Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, India.
authors.forename: J P
authors.initials: JP
authors.lastname: Kachhawa
authors.affiliation: Veterinary Hospital, Haripura, Hanumangarh, Rajasthan, India.
authors.forename: Surender
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department of Clinical Veterinary Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, India.
authors.forename: Ankita
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Clinical Veterinary Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, India.
authors.forename: A P
authors.initials: AP
authors.lastname: Singh
authors.affiliation: Department of Clinical Veterinary Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, India.
authors.forename: Anil
authors.initials: A
authors.lastname: Ahuja
keywords: blood transfusion; buparvaquone; calves; hemato-biochemical; theileriosis