title: Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Serafin
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Lissandron
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Buldini
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Bresolin
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Paganin
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Grillo
authors.affiliation: Centro Ricerca Tettamanti, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Andriano
authors.affiliation: Centro Ricerca Tettamanti, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Palmi
authors.affiliation: Centro Ricerca Tettamanti, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Cazzaniga
authors.affiliation: Department of Surgery, Medicine, Dentistry and Morphology, University of Modena and Reggio Emilia, Modena, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Marmiroli
authors.affiliation: Center of Hemato-Oncology, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Ospedale San Gerardo, Monza, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Conter
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Basso
authors.affiliation: Department of Woman's and Child's Health, University of Padova, Padova, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Accordi
mesh_terms: D019703:Calcineurin / Q000378:metabolism*; D002478:Cells, Cultured; D006412:Hematopoietic Stem Cells / Q000378:metabolism; D006801:Humans; D019860:Lymphocyte Specific Protein Tyrosine Kinase p56(lck) / Q000378:metabolism*; D022423:Myeloid Cells / Q000378:metabolism; D010766:Phosphorylation / Q000502:physiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000378:metabolism*; D054504:Precursor Cells, T-Lymphoid / Q000378:metabolism*; D020543:Proteome / Q000378:metabolism; D050796:STAT3 Transcription Factor / Q000378:metabolism*; D058570:TOR Serine-Threonine Kinases / Q000378:metabolism*; D059467:Transcriptome / Q000502:physiology
chemical_list: D020543:Proteome; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; C546842:MTOR protein, human; D019860:Lymphocyte Specific Protein Tyrosine Kinase p56(lck); D058570:TOR Serine-Threonine Kinases; D019703:Calcineurin