title: [To enhance study on translation and application of mesenchymal stem cells in wound repair].
abstract: Wound repair is a complicated process of interactions among numerous types of cells, involving the activation of multiple cells and various cytokines. The extensive burn and chronic wound are already big challenges for clinic due to the limitations of existing treatment means. Stem cell technology, as a new therapy, may be the optimum choice for wound repair. Mesenchymal stem cells are multipotent cells with self-renewal and differentiation capacity and have a broad tissue distribution, which are promising in treating wound, and it is worthy to discuss and analyze their role, clinical translation and application in wound repair, the facing problems at present and solving strategies as well.
authors.affiliation: Burn Center of PLA, Department of Burns and Cutaneous Surgery, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China.
authors.forename: D H
authors.initials: DH
authors.lastname: Hu
authors.forename: W
authors.initials: W
authors.lastname: Zhang
mesh_terms: D002056:Burns / Q000473:pathology / Q000628:therapy*; D002454:Cell Differentiation; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000502:physiology; D012867:Skin / Q000293:injuries* / Q000378:metabolism; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology*
keywords: Mesenchymal stem cells; Translation and application; Wound healing