title: Micro X-Ray Computed Tomography Mass Loss Assessment of Different UHMWPE: A Hip Joint Simulator Study on Standard vs. Cross-Linked Polyethylene.
abstract: More than 60.000 hip arthroplasty are performed every year in Italy. Although Ultra-High-Molecular-Weight-Polyethylene remains the most used material as acetabular cup, wear of this material induces over time in vivo a foreign-body response and consequently osteolysis, pain, and the need of implant revision. Furthermore, oxidative wear of the polyethylene provoke several and severe failures. To solve these problems, highly cross-linked polyethylene and Vitamin-E-stabilized polyethylene were introduced in the last years. In in vitro experiments, various efforts have been made to compare the wear behavior of standard PE and vitamin-E infused liners. In this study we compared the in vitro wear behavior of two different configurations of cross-linked polyethylene (with and without the add of Vitamin E) vs. the standard polyethylene acetabular cups. The aim of the present study was to validate a micro X-ray computed tomography technique to assess the wear of different commercially available, polyethylene's acetabular cups after wear simulation; in particular, the gravimetric method was used to provide reference wear values. The agreement between the two methods is documented in this paper.
authors.affiliation: Medical Technology Laboratory, Rizzoli Orthopaedic Institute, Bologna-Italy.
authors.forename: Saverio
authors.identifier: http://orcid.org/0000-0003-3615-6085
authors.initials: S
authors.lastname: Affatato
authors.affiliation: Department of Management and Engineering, University of Padova, Vicenza-Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Zanini
authors.affiliation: Department of Management and Engineering, University of Padova, Vicenza-Italy.
authors.forename: Simone
authors.initials: S
authors.lastname: Carmignato
mesh_terms: D003432:Cross-Linking Reagents / Q000737:chemistry*; D006621:Hip Joint / Q000000981:diagnostic imaging*; D006801:Humans; D020959:Polyethylene / Q000737:chemistry*; D011095:Polyethylenes / Q000737:chemistry*; D055114:X-Ray Microtomography / Q000379:methods*
chemical_list: D003432:Cross-Linking Reagents; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D020959:Polyethylene