title: [Analysis on mortality of cervical cancer and its temporal trend in women in China, 2006-2012].
abstract: Objective:To analyze the mortality of cervical cancer and its temporal trend in women in China between 2006 and 2012.Methods:The cause-of-death data about cervical cancer, which was abstracted from National Disease Surveillance Points and adjusted by special survey for underreporting, was used to analyze the age and area specific crude mortality rates of cervical cancer in China during 2006-2012. The age-standardized mortality rate was calculated by using world standardized population (Segi's). The Joinpoint regression model was used to obtain annual percentage change and 95%CIfor assessing the time trend of mortality rate of cervical cancer from 2006 to 2012.Results:In 2012, the crude mortality rate of cervical cancer was 3.15 per 100 000 in women in China. The mortality rate in rural area (3.45/100 000) was higher than that in urban area (2.76/100 000), while the central area had the highest mortality rate of cervical cancer (3.77/100 000) compared with western area (3.23/100 000) and eastern area (2.54/100 000). The Segi's age-standardized mortality rate in eastern area increased by 2.9%(95%CI: 0.8%-5.0%) annually, an increase of 6.0%was observed in age group 30-59 years (95%CI: 1.6%-10.5%). However, the Segi's age-standardized mortality rate in central area declined by 4.6%(95%CI: -5.9%- -3.3%), where the declines of 3.2%and 5.7%were observed in age groups 30-59 years and ≥60 years (95%CI: - 5.0%-- 1.4%and 95% CI: - 9.3%--2.0%) and respectively. There was no significant change in cervical cancer mortality in western area. The similar trends were observed in the age-standardized mortality rate calculated according to the population of China.Conclusions:The decline of overall mortality rate of cervical cancer tended to stop in China and significant differences still exist among different areas. Our results suggest that the central/western areas and rural areas are still key areas for cervical cancer prevention and control and close attention should be paid to the increase of cervical cancer mortality in women aged 35-59 years in eastern area. It is essential to establish a systematic cervical cancer prevention network with larger population coverage to reduce the deaths caused by cervical cancer.
authors.affiliation: Division of Cancer Control and Prevention, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
authors.forename: H L
authors.initials: HL
authors.lastname: Bao
authors.affiliation: Division of Vital Statistics and Death Surveillance, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
authors.forename: Y N
authors.initials: YN
authors.lastname: Liu
authors.affiliation: Division of Vital Statistics and Death Surveillance, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
authors.forename: L J
authors.initials: LJ
authors.lastname: Wang
authors.affiliation: Division of Cancer Control and Prevention, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
authors.forename: L W
authors.initials: LW
authors.lastname: Fang
authors.affiliation: Division of Cancer Control and Prevention, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
authors.forename: S
authors.initials: S
authors.lastname: Cong
authors.affiliation: National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
authors.forename: M G
authors.initials: MG
authors.lastname: Zhou
authors.affiliation: National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
authors.forename: L H
authors.initials: LH
authors.lastname: Wang
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D009026:Mortality / Q000639:trends*; D011159:Population Surveillance; D012042:Registries; D012424:Rural Population; D014505:Urban Population; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000401:mortality*
keywords: Cervical cancer; Mortality; Surveillance; Time trend