title: Hyponatremic hypertensive syndrome - a retrospective cohort study.
abstract: OBJECTIVE
  To ascertain the frequency of hyponatremic hypertensive syndrome (HHS) in a cohort of children with hypertensive emergency in a tertiary pediatric hospital.
  
  
  METHODS
  A retrospective review was undertaken among children with hypertensive emergency admitted in our tertiary children hospital between June 2014 and December 2015 with an aim to identify any children with HHS. Three children with HHS were identified during this period.
  
  
  RESULTS
  The 3 patients with HHS presented with hypertensive emergency. They were initially managed with Labetalol infusion and thereafter switched to oral anti-hypertensives (combination of Nifedipine sustained release, Hydralazine and Beta Blocker). All 3 were diagnosed to have unilateral renal artery stenosis. One child was lost to follow up, whereas the other 2 underwent renal angioplasty which was followed with normalization of blood pressure.
  
  
  CONCLUSIONS
  Despite activation of renin angiotensin axis secondary to renal artery stenosis, these groups of children have significant hyponatremia. Renal re-vascularisation produces excellent results in most of them.
authors.affiliation: Devdeep Mukherjee, Rajiv Sinha, Md Shakil Akhtar, Department of Pediatric Medicine, Institute of Child Health, Kolkata 700017, India.
authors.forename: Devdeep
authors.initials: D
authors.lastname: Mukherjee
authors.affiliation: Devdeep Mukherjee, Rajiv Sinha, Md Shakil Akhtar, Department of Pediatric Medicine, Institute of Child Health, Kolkata 700017, India.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Sinha
authors.affiliation: Devdeep Mukherjee, Rajiv Sinha, Md Shakil Akhtar, Department of Pediatric Medicine, Institute of Child Health, Kolkata 700017, India.
authors.forename: Md Shakil
authors.initials: MS
authors.lastname: Akhtar
authors.affiliation: Devdeep Mukherjee, Rajiv Sinha, Md Shakil Akhtar, Department of Pediatric Medicine, Institute of Child Health, Kolkata 700017, India.
authors.forename: Agni Sekhar
authors.initials: AS
authors.lastname: Saha
keywords: Encephalopathy; Hypertension; Hyponatremia; Paediatric; Renovascular