title: Pulmonary vascular and cardiac impairment in interstitial lung disease.
abstract: Pulmonary vascular and cardiac impairment is increasingly appreciated as a major adverse factor in the natural history of interstitial lung disease. This clinically orientated review focuses on the current concepts in the pathogenesis, pathophysiology and implications of the detrimental sequence of increased pulmonary vascular resistance, pre-capillary pulmonary hypertension and right heart failure in interstitial lung disease, and provides guidance on its management.
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.
authors.forename: Marios
authors.initials: M
authors.lastname: Panagiotou
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.
authors.forename: Alistair C
authors.initials: AC
authors.lastname: Church
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.
authors.forename: Martin K
authors.initials: MK
authors.lastname: Johnson
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Peacock
mesh_terms: D000818:Animals; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D011379:Prognosis; D011652:Pulmonary Circulation; D012307:Risk Factors; D018497:Ventricular Dysfunction, Right / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D016278:Ventricular Function, Right