title: Reverse hybrid total hip arthroplasty.
abstract: Background and purpose - The use of a cemented cup together with an uncemented stem in total hip arthroplasty (THA) has become popular in Norway and Sweden during the last decade. The results of this prosthetic concept, reverse hybrid THA, have been sparsely described. The Nordic Arthroplasty Register Association (NARA) has already published 2 papers describing results of reverse hybrid THAs in different age groups. Based on data collected over 2 additional years, we wanted to perform in depth analyses of not only the reverse hybrid concept but also of the different cup/stem combinations used. Patients and methods - From the NARA, we extracted data on reverse hybrid THAs from January 1, 2000 until December 31, 2013. 38,415 such hips were studied and compared with cemented THAs. The Kaplan-Meier method and Cox regression analyses were used to estimate the prosthesis survival and the relative risk of revision. The main endpoint was revision for any reason. We also performed specific analyses regarding the different reasons for revision and analyses regarding the cup/stem combinations used in more than 500 cases. Results - We found a higher rate of revision for reverse hybrids than for cemented THAs, with an adjusted relative risk of revision (RR) of 1.4 (95% CI: 1.3-1.5). At 10 years, the survival rate was 94% (CI: 94-95) for cemented THAs and 92% (95% CI: 92-93) for reverse hybrids. The results for the reverse hybrid THAs were inferior to those for cemented THAs in patients aged 55 years or more (RR =1.1, CI: 1.0-1.3; p < 0.05). We found a higher rate of early revision due to periprosthetic femoral fracture for reverse hybrids than for cemented THAs in patients aged 55 years or more (RR =3.1, CI: 2.2-4.5; p < 0.001). Interpretation - Reverse hybrid THAs had a slightly higher rate of revision than cemented THAs in patients aged 55 or more. The difference in survival was mainly caused by a higher incidence of early revision due to periprosthetic femoral fracture in the reversed hybrid THAs.
authors.affiliation: a Department of Orthopaedic Surgery, Elverum , Innlandet Hospital Trust.
authors.forename: Helge
authors.initials: H
authors.lastname: Wangen
authors.affiliation: b The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery , Haukeland University Hospital , Bergen.|c Department of Clinical Medicine , University of Bergen , Bergen , Norway.
authors.forename: Leif I
authors.initials: LI
authors.lastname: Havelin
authors.affiliation: b The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery , Haukeland University Hospital , Bergen.
authors.forename: Anne M
authors.initials: AM
authors.lastname: Fenstad
authors.affiliation: b The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery , Haukeland University Hospital , Bergen.
authors.forename: Geir
authors.initials: G
authors.lastname: Hallan
authors.affiliation: b The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery , Haukeland University Hospital , Bergen.|c Department of Clinical Medicine , University of Bergen , Bergen , Norway.
authors.forename: Ove
authors.initials: O
authors.lastname: Furnes
authors.affiliation: d Competence Centre for Clinical Epidemiology and Biostatistics, North, Department of Clinical Epidemiology , Aarhus University Hospital , Aarhus.|f The Danish Hip Arthroplasty Register, Department of Clinical Epidemiology , Aarhus University Hospital , Aarhus , Denmark.
authors.forename: Alma B
authors.initials: AB
authors.lastname: Pedersen
authors.affiliation: e Department of Orthopaedic Surgery , Traumatology and Clinical Institute, Odense University Hospital , Odense.|f The Danish Hip Arthroplasty Register, Department of Clinical Epidemiology , Aarhus University Hospital , Aarhus , Denmark.
authors.forename: Søren
authors.initials: S
authors.lastname: Overgaard
authors.affiliation: g The Swedish Hip Arthroplasty Register.|h Department of Orthopaedics , Institute of Surgical Sciences, Sahlgrenska University Hospital , Gothenburg , Sweden.
authors.forename: Johan
authors.initials: J
authors.lastname: Kärrholm
authors.affiliation: g The Swedish Hip Arthroplasty Register.|h Department of Orthopaedics , Institute of Surgical Sciences, Sahlgrenska University Hospital , Gothenburg , Sweden.
authors.forename: Göran
authors.initials: G
authors.lastname: Garellick
authors.affiliation: i Department of Orthopaedics and Traumatology , Turku University Hospital , Turku.|j The Finnish Arthroplasty Register.
authors.forename: Keijo
authors.initials: K
authors.lastname: Mäkelä
authors.affiliation: j The Finnish Arthroplasty Register.|k The Coxa Hospital for Joint Replacement , Tampere , Finland.
authors.forename: Antti
authors.initials: A
authors.lastname: Eskelinen
authors.affiliation: l University of Oslo , Oslo.|m Department of Orthopaedics , Oslo University Hospital , Oslo , Norway.
authors.forename: Lars
authors.initials: L
authors.lastname: Nordsletten
mesh_terms: D000367:Age Factors; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000379:methods*; D002484:Cementation / Q000009:adverse effects / Q000379:methods*; D005260:Female; D005264:Femoral Fractures / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D057068:Periprosthetic Fractures / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D011474:Prosthesis Design; D011475:Prosthesis Failure / Q000209:etiology; D012042:Registries; D012086:Reoperation / Q000706:statistics & numerical data; D012307:Risk Factors; D012537:Scandinavian and Nordic Countries / Q000453:epidemiology