title: Prevalence and Risk Factors of Gastric Adenoma and Gastric Cancer in Colorectal Cancer Patients.
abstract: Background/Aims. To evaluate the incidence of gastric adenoma and gastric cancer in colorectal cancer patients, as well as the clinicopathological features that affect their incidence.Methods. Among patients who underwent surgery after being diagnosed with colorectal cancer between January 2004 and December 2013 at Chungnam National University Hospital, 142 patients who underwent follow-up upper gastrointestinal endoscopy were assigned to the patient group. The control group included 426 subjects randomly selected. The patient group was subdivided into two: one that developed gastric adenoma or cancer and one that did not. Clinicopathological characteristics were compared between these groups.Results. In total, 35 (24.6%) colorectal cancer patients developed a gastric adenoma or gastric cancer, which was higher than the number in the control group (20 [4.7%] patients;p< 0.001). Age, alcohol history, and differentiation of colorectal cancer were associated with higher risks of gastric adenoma or gastric cancer, with odds ratios of 1.062, 6.506, and 5.901, respectively.Conclusions. In colorectal cancer patients, screening with upper gastrointestinal endoscopy is important, even if no lesions are noted in the upper gastrointestinal tract at colorectal cancer diagnosis. Endoscopic screening is particularly important with increasing age, history of alcohol consumption, and poor cancer differentiation.
authors.affiliation: Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
authors.forename: Dae Hyun
authors.identifier: 0000-0002-4587-3089
authors.initials: DH
authors.lastname: Tak
authors.affiliation: Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
authors.forename: Hee Seok
authors.identifier: 0000-0002-8806-2163
authors.initials: HS
authors.lastname: Moon
authors.affiliation: Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
authors.forename: Sun Hyung
authors.identifier: 0000-0002-1913-4346
authors.initials: SH
authors.lastname: Kang
authors.affiliation: Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
authors.forename: Jae Kyu
authors.identifier: 0000-0002-9068-624X
authors.initials: JK
authors.lastname: Sung
authors.affiliation: Division of Gastroenterology, Departments of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
authors.forename: Hyun Yong
authors.initials: HY
authors.lastname: Jeong