title: Successful surgical treatment for squamous cell carcinoma arising from hidradenitis suppurativa: A case report and literature review.
abstract: BACKGROUND
  Hidradenitis suppurativa (HS) is a disabling inflammatory disease mainly affecting apocrine glands. Marjolin ulcer (MU) is a term used to describe a rare type of squamous cell carcinoma (SCC) arising within sites of chronic wounds or preexisting scars. Chronic HS may result in a rare type of SCC, MU, which has a poor prognosis due to its high metastatic rate.
  Here we reported a 60-year-old male who developed SCC on the right buttock after suffering from HS for 15 years.
  
  
  METHODS
  Radical resection with clear margin was performed, after which topical negative pressure (TNP) was applied followed by split-thickness skin grafting.
  
  
  RESULTS
  In a 1-year follow-up, there was no recurrence of malignancy.
  
  
  CONCLUSIONS
  Cases reported in English literature since 1991 were reviewed to get a general grasp of status quo. The authors conclude that chronic HS lesion especially in the gluteal region should be cautiously observed. Once tumor arisen from HS lesion, immediate radical excision should be performed. With assured clear margin, TNP could be chosen to offer a favorable environment for the survival of skin grafting.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Beijing, P.R. China Department of Medicine, the University of Melbourne, Parkville, Victoria, Australia Department of Pathology, Peking Union Medical College Hospital, Beijing, P.R. China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Huang
authors.forename: Zhichao
authors.initials: Z
authors.lastname: Lai
authors.forename: Mu
authors.initials: M
authors.lastname: He
authors.forename: Biyun
authors.initials: B
authors.lastname: Zhai
authors.forename: Liangrui
authors.initials: L
authors.lastname: Zhou
authors.forename: Xiao
authors.initials: X
authors.lastname: Long
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000601:surgery*; D017497:Hidradenitis Suppurativa / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D012883:Skin Ulcer / Q000209:etiology / Q000473:pathology / Q000601:surgery*