title: Source of Ectopic ACTH Secretion Easily Identified by 68 Ga DOTANOC PET/CT.
abstract: Malignant tumors account for most sources of ectopic ACTH Cushing syndrome (EA-CS). Early localization of the source and complete removal can be curative and also prevent metastasis. Diagnostic CT is known to perform better than PET/CT (low dose) in characterizing lung pathologies. However, bronchial carcinoids, a common source of EA-CS, may be difficult to detect on chest CT scan especially when it is small and located close to the hilar region. We present a case of EA-CS due to bronchial carcinoid, which was easily seen on Ga DOTANOC PET/CT after a diagnostic chest CT was reported as normal.
authors.affiliation: From the Nuclear Medicine Division, Groote Schuur Hospital/University of Cape Town, Cape Town, South Africa.
authors.forename: Sofiullah
authors.initials: S
authors.lastname: Abubakar
authors.forename: Yaw Ampem
authors.initials: YA
authors.lastname: Amoako
authors.forename: Tessa
authors.initials: T
authors.lastname: Kotze
authors.forename: Naima
authors.initials: N
authors.lastname: Tag
mesh_terms: D000182:ACTH Syndrome, Ectopic / Q000000981:diagnostic imaging*; D001984:Bronchial Neoplasms / Q000000981:diagnostic imaging*; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging*; D003480:Cushing Syndrome / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009942:Organometallic Compounds; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals
chemical_list: C504894:68Ga-DOTANOC; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals