title: Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study.
abstract: Lumbar disc herniation (LDH) is rare in the adolescent population. Factors predisposing to LDH in adolescents differ from adults with more cases being related to trauma or structural malformations. Further, there are limited data on patient-reported outcomes after lumbar microdiscectomy in adolescents. Our aim was to compare clinical outcomes at 1 year following single-level lumbar microdiscectomy in adolescents (13-19 years old) compared to younger adults (20-50 years old) with LDH.
  
  
  
  Data were collected through the Norwegian Registry for Spine Surgery. Patients were eligible if they had radiculopathy due to LDH, underwent single-level lumbar microdiscectomy between January 2007 and May 2014, and were between 13 and 50 years old at time of surgery. The primary endpoint was change in Oswestry Disability Index (ODI) 1 year after surgery. Secondary endpoints were generic quality of life (EuroQol five dimensions [EQ-5D]), back pain numerical rating scale (NRS), leg pain NRS and complications.
  
  
  
  A total of 3,245 patients were included (97 patients 13-19 years old and 3,148 patients 20-50 years old). A significant improvement in ODI was observed for the whole population, but there was no difference between groups (0.6; 95% CI, -4.5 to 5.8; p = 0.811). There were no differences between groups concerning EQ-5D (-0.04; 95% CI, -0.15 to 0.07; p = 0.442), back pain NRS (-0.4; 95% CI, -1.2 to 0.4; p = 0.279), leg pain NRS (-0.4; 95% CI, -1.2 to 0.5; p = 0.374) or perioperative complications (1.0% for adolescents, 5.1% for adults, p = 0.072).
  
  
  
  The effectiveness and safety of single-level microdiscectomy are similar in adolescents and the adult population at 1-year follow-up.
authors.affiliation: Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway.|Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.|National Advisory Unit on Spinal Surgery, St. Olavs University Hospital, Trondheim, Norway.
authors.forename: Sasha
authors.initials: S
authors.lastname: Gulati
authors.affiliation: Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway.
authors.forename: Mattis A
authors.initials: MA
authors.lastname: Madsbu
authors.affiliation: Department of Neurosurgery, University Hospital of Northern Norway (UNN), Tromsø, Norway.|The Norwegian National Registry for Spine Surgery, University Hospital of Northern Norway (UNN), Tromsø, Norway.
authors.forename: Tore K
authors.initials: TK
authors.lastname: Solberg
authors.affiliation: Department of Neurosurgery, University Hospital of Northern Norway (UNN), Tromsø, Norway.|The Norwegian National Registry for Spine Surgery, University Hospital of Northern Norway (UNN), Tromsø, Norway.
authors.forename: Andreas
authors.initials: A
authors.lastname: Sørlie
authors.affiliation: Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.|Department of Medicine, Ålesund Hospital, Ålesund, Norway.
authors.forename: Charalampis
authors.initials: C
authors.lastname: Giannadakis
authors.affiliation: Department of Paediatrics, Rikshospitalet, Oslo University Hospital, Oslo, Norway.
authors.forename: Marius K
authors.initials: MK
authors.lastname: Skram
authors.affiliation: Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway.|Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.|National Advisory Unit on Spinal Surgery, St. Olavs University Hospital, Trondheim, Norway.|The Norwegian National Registry for Spine Surgery, University Hospital of Northern Norway (UNN), Tromsø, Norway.
authors.forename: Øystein P
authors.initials: ØP
authors.lastname: Nygaard
authors.affiliation: Department of Neurosurgery, St. Olavs University Hospital, Trondheim, Norway. legepost@gmail.com.|Department of Neurosurgery, Sahlgrenska University Hospital, Blå Stråket 5, vån 3, 413 45, Göteborg, Sweden. legepost@gmail.com.|Institute of Neuroscience and Physiology, Sahlgrenska Academy, Gothenburg, Sweden. legepost@gmail.com.
authors.forename: Asgeir S
authors.initials: AS
authors.lastname: Jakola
mesh_terms: D000293:Adolescent; D000328:Adult; D017586:Diskectomy / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000601:surgery; D008297:Male; D011183:Postoperative Complications; D011446:Prospective Studies; D011788:Quality of Life; D012585:Sciatica / Q000601:surgery*; D016896:Treatment Outcome
keywords: Adolescent; Disc herniation; Microdiscectomy; Spine