title: Prevalence of attention deficit/hyperactivity disorder among children and adolescents in China: a systematic review and meta-analysis.
abstract: Attention deficit/hyperactivity disorder (ADHD), the most common childhood neurobehavioural disorder, can produce a series of negative effects on children, adolescents, and even adults as well as place a serious economic burden on families and society. However, the prevalence of ADHD is not well understood in China. The goal of this study was to estimate the pooled prevalence of ADHD among children and adolescents in China using a systematic review and meta-analysis.
  
  
  
  A systematic literature search was conducted in PubMed, Web of Science, MEDLINE, CNKI, Wanfang, Weipu and CBM databases, and relevant articles published from inception to March 1, 2016, that provided the prevalence of ADHD among children and adolescents in China were reviewed. The risk of bias in individual studies was assessed using the Risk of Bias Tool for prevalence studies. Pooled-prevalence estimates were calculated with a random-effects model. Sources of heterogeneity were explored using subgroup analyses.
  
  
  
  Sixty-seven studies with a total of 275,502 individuals were included in this study. The overall pooled-prevalence of ADHD among children and adolescents in China was 6.26% (95% CI: 5.36-7.22%) with significant heterogeneity (I2= 99.0%, P < 0.001). The subgroup analyses showed that, the variables "geographic location" and "source of information" partially explained of the heterogeneity in this study (P < 0.05). The prevalence of ADHD-I was the highest of the subtypes, followed by ADHD-HI and ADHD-C.
  
  
  
  The prevalence of ADHD among children and adolescents in China is generally consistent with the worldwide prevalence and shows that ADHD affects quite a large number of people under 18 years old. However, a nationwide study is needed to provide more accurate estimations.
authors.affiliation: Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 238 Shang Ma Yuan Ling Xiang Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Wang
authors.affiliation: Department of Toxicology, Xiangya School of Public Health, Central South University, Changsha, Hunan Province, China.
authors.forename: Kaihua
authors.initials: K
authors.lastname: Liu
authors.affiliation: Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
authors.forename: Zhanzhan
authors.initials: Z
authors.lastname: Li
authors.affiliation: Deyang Center for Disease Control and Prevention, Sichuan Province, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Xu
authors.affiliation: Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 238 Shang Ma Yuan Ling Xiang Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 238 Shang Ma Yuan Ling Xiang Xiangya Road, Kaifu District, Changsha, Hunan Province, China.
authors.forename: Wenpei
authors.initials: W
authors.lastname: Shi
authors.affiliation: Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 238 Shang Ma Yuan Ling Xiang Xiangya Road, Kaifu District, Changsha, Hunan Province, China. liche4005@126.com.
authors.forename: Lizhang
authors.initials: L
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis* / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence
keywords: Attention deficit/hyperactivity disorder; China; Meta-analysis; Prevalence