title: Synthesis of chiral sultams via palladium-catalyzed intramolecular asymmetric reductive amination.
abstract: A novel palladium-catalyzed intramolecular reductive amination of ketones with weakly nucleophilic sulfonamides has been developed in the presence of a Brønsted acid, giving a wide range of chiral γ-, δ-, and ε-sultams in high yields and up to 99% of enantioselectivity.
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, P. R. China. ygzhou@dicp.ac.cn.
authors.forename: Bo
authors.initials: B
authors.lastname: Song
authors.forename: Chang-Bin
authors.initials: CB
authors.lastname: Yu
authors.forename: Yue
authors.initials: Y
authors.lastname: Ji
authors.forename: Mu-Wang
authors.initials: MW
authors.lastname: Chen
authors.forename: Yong-Gui
authors.initials: YG
authors.lastname: Zhou