title: Bone Grafting of Atlantoaxial Joints and Occipitocervical or Atlantoaxial Fusion for the Reduction and Fixation of Basilar Invagination with Atlantoaxial Dislocation by a Posterior Approach: A Preliminary Study.
abstract: BACKGROUND
  Basilar invagination (BI) with atlantoaxial dislocation (AAD) is a complex disease to manage. We have developed a new technique of bone grafting the atlantoaxial joints and occipitocervical fusion using a posterior approach for the reduction and fixation of BI with AAD with complete retention of the C2 nerve root.
  
  
  METHODS
  Thirty-two patients underwent bone grafting of the atlantoaxial joints and occipitocervical fusion for the reduction and fixation of BI with AAD by the posterior approach in our department between January 2015 and February 2016. All patients underwent plain radiography, computed tomography (CT) scanning, and magnetic resonance imaging evaluation. The atlantodens interval and cervicomedullary angle were evaluated preoperatively and 5 days after surgery on sagittal reconstructed CT scans to evaluate BI with AAD. CT scans of sagittal reconstruction were acquired at each follow-up until bone fusion was confirmed.
  
  
  RESULTS
  All patients were followed up for 6-19 months. No patient required re-exploration for failure of implant fixation. At the last follow-up, all patients had achieved fusion (32/32). Japanese Orthopedic Association score, atlantodens interval, and cervicomedullary angle were significantly improved in these patients compared with preoperative measurements (P < 0.05). The duration of symptoms ranged from 5 days to 11 months (mean duration, 2 months). No serious complication was observed.
  
  
  CONCLUSIONS
  In this preliminary study, our operation technique could treat BI with AAD by using only a posterior approach, which could retain C2 nerve roots and fuse atlantoaxial joints. This technique may be extended to other diseases requiring treatment by C1-C2 fusion.
authors.affiliation: Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, China.
authors.forename: Xin
authors.initials: X
authors.lastname: He
authors.affiliation: Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, China.
authors.forename: Yibin
authors.initials: Y
authors.lastname: Meng
authors.affiliation: Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, China.
authors.forename: Jianan
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, China.
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Hang
authors.affiliation: Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, China.
authors.forename: Junsong
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, China.
authors.forename: Qining
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, China. Electronic address: haodjspine@126.com.
authors.forename: Dingjun
authors.initials: D
authors.lastname: Hao
mesh_terms: D000328:Adult; D001139:Arnold-Chiari Malformation / Q000473:pathology / Q000601:surgery*; D001268:Atlanto-Axial Joint / Q000002:abnormalities* / Q000473:pathology / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D000013:Congenital Abnormalities / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D016268:Internal Fixators; D004204:Joint Dislocations / Q000473:pathology / Q000601:surgery*; D008297:Male; D010865:Pilot Projects; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome
keywords: Atlantoaxial dislocation; Atlantoaxial joints; Basilar invagination; Posterior approach