title: Combined surgical therapy of advanced peri-implantitis evaluating two methods of surface decontamination: a 7-year follow-up observation.
abstract: To assess the long-term outcomes (>4 years) following combined surgical resective/regenerative therapy of advanced peri-implantitis lesions using two surface decontamination methods.
  
  
  
  Fifteen patients (n = 15 combined supra- and intrabony defects) completed a follow-up observation period of 7 years. The treatment procedure included access flap surgery, granulation tissue removal and implantoplasty at buccally and supracrestally exposed implant parts, and a randomly assigned decontamination of the unmodified intrabony implant surface areas using either (i) an Er:YAG laser (ERL) or (ii) plastic curettes + cotton pellets + sterile saline (CPS). Intrabony defects were filled using a natural bone mineral and covered by a native collagen membrane.
  
  
  
  At 7 years, both ERL and CPS were associated with similar mean bleeding on probing reductions (CPS: 89.99 ± 11.65% versus ERL: 86.66 ± 18.26%) and clinical attachment level gains (CPS: 2.76 ± 1.92 mm versus ERL: 2.06 ± 2.52 mm).
  
  
  
  Combined surgical resective/regenerative therapy of advanced peri-implantitis was effective on the long-term, but not influenced by the initial method of surface decontamination.
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Gordon
authors.initials: G
authors.lastname: John
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Schmucker
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Narja
authors.initials: N
authors.lastname: Sahm
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Becker
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008875:Middle Aged; D019647:Oral Surgical Procedures / Q000379:methods; D057873:Peri-Implantitis / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome
keywords: bone graft; collagen membrane; implantoplasty; peri-implantitis; surgical regenerative therapy