title: Pathogenesis: common pathways between hidradenitis suppurativa and Crohn disease.
abstract: Both hidradenitis suppurativa and Crohn disease are considered chronic inflammatory diseases due to immune dysregulation. The high prevalence of Crohn disease patients diagnosed with hidradenitis suppurativa suggests the existence of common pathogenic links. The present literature review analyses the similarities and differences in the pathogenesis of the two diseases, in the search for new research and knowledge targets.
authors.affiliation: Servicio de Dermatología, Hospital Universitario del Sureste, Arganda del Rey, Madrid, España. Electronic address: fjgarcia@aedv.es.
authors.forename: F J
authors.initials: FJ
authors.lastname: García Martínez
authors.affiliation: Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón-IiSGM, Madrid, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, España; Departamento de Medicina, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.
authors.forename: L
authors.initials: L
authors.lastname: Menchén
mesh_terms: D056704:Adaptive Immunity; D001343:Autophagy / Q000235:genetics; D018988:Bacterial Translocation / Q000235:genetics; D015984:Causality; D015897:Comorbidity; D003424:Crohn Disease / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D016207:Cytokines / Q000378:metabolism; D004781:Environmental Exposure; D005799:Genes, Dominant; D020022:Genetic Predisposition to Disease; D017497:Hidradenitis Suppurativa / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D008213:Lymphocyte Activation / Q000235:genetics; D064307:Microbiota; D009765:Obesity / Q000453:epidemiology; D012907:Smoking / Q000009:adverse effects; D013315:Stress, Psychological / Q000150:complications / Q000276:immunology; D051193:Toll-Like Receptors / Q000276:immunology
chemical_list: D016207:Cytokines; D051193:Toll-Like Receptors
keywords: Crohn disease; Enfermedad de Crohn; Enfermedad inflamatoria intestinal; Etiopatogenia; Hidradenitis suppurativa; Hidradenitis supurativa; Inflammatory bowel disease; Pathogenesis