title: FGF23 and inflammation.
abstract: Systemic inflammation is a recognized feature in chronic kidney disease (CKD). The role of systemic inflammation in the pathogenesis of vascular calcification was recently settled. FGF23 was recently accused as a direct stimulus of systemic inflammation. This finding explains the strong association of FGF23 to vascular calcification and increased mortality among CKD.
authors.affiliation: Usama A A Sharaf El Din, Department of Nephrology, School of Medicine, Cairo University, Nasr City, Cairo 11759, Egypt.
authors.forename: Usama A A
authors.initials: UA
authors.lastname: Sharaf El Din
authors.affiliation: Usama A A Sharaf El Din, Department of Nephrology, School of Medicine, Cairo University, Nasr City, Cairo 11759, Egypt.
authors.forename: Mona M
authors.initials: MM
authors.lastname: Salem
authors.affiliation: Usama A A Sharaf El Din, Department of Nephrology, School of Medicine, Cairo University, Nasr City, Cairo 11759, Egypt.
authors.forename: Dina O
authors.initials: DO
authors.lastname: Abdulazim
keywords: Chronic kidney disease; FGF23; Inflammation; Phosphate binders; Vascular calcification