title: Dimensions of Attention Associated With the Microstructure of Corona Radiata White Matter.
abstract: Mirsky proposed a model of attention that included these dimensions: focus/execute, sustain, stabilize, encode, and shift. The neural correlates of these dimensions were investigated within corona radiata subregions in healthy youth. Diffusion tensor imaging and neuropsychological assessments were conducted in 79 healthy, right-handed youth aged 4-17 years. Diffusion tensor imaging maps were analyzed using standardized parcellation methods. Partial Pearson correlations between neuropsychological standardized scores, representing these attention dimensions, and diffusion tensor imaging measures of corona radiata subregions were calculated after adjusting for gender and IQ. Significant correlations were found between the focus/execute, sustain, stabilize, and shift dimensions and imaging metrics in hypothesized corona radiata subregions. Results suggest that greater microstructural white matter integrity of the corona radiata is partly associated with attention across 4 attention dimensions. Findings suggest that white matter microstructure of the corona radiata is a neural correlate of several, but not all, attention dimensions.
authors.affiliation: 1 Department of Radiology, Duke University School of Medicine, Durham, NC, USA.|2 Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
authors.forename: Elise A
authors.initials: EA
authors.lastname: Stave
authors.affiliation: 3 Department of Psychiatry and Behavioral Sciences, Healthy Childhood Brain Development and Developmental Traumatology Research Program, Duke University School of Medicine, Durham, NC, USA.
authors.forename: Michael D
authors.initials: MD
authors.lastname: De Bellis
authors.affiliation: 2 Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.|4 Departments of Psychiatry and Allied Health Sciences, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
authors.forename: Steven R
authors.initials: SR
authors.lastname: Hooper
authors.affiliation: 2 Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
authors.forename: Donald P
authors.initials: DP
authors.lastname: Woolley
authors.affiliation: 5 Hallym University Dongtan Sacred Heart Hospital, Hwasung City, Gyeonggi-do, Republic of Korea.
authors.forename: Suk Ki
authors.initials: SK
authors.lastname: Chang
authors.affiliation: 1 Department of Radiology, Duke University School of Medicine, Durham, NC, USA.
authors.forename: Steven D
authors.initials: SD
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000000981:diagnostic imaging* / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D056324:Diffusion Tensor Imaging; D056344:Executive Function / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D066127:White Matter / Q000000981:diagnostic imaging*
keywords: Mirsky; attention; corona radiata; diffusion tensor imaging; encode; focus/execute; neuropsychology; shift; stabilize; sustain