title: PTEN deficiency permits the formation of pancreatic cancer in the absence of autophagy.
authors.affiliation: Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.|Comprehensive Cancer Center Mainfranken, Josef-Schneider Str. 6, Wuerzburg, Germany.|Department of Pathology, University of Wuerzburg, Josef-Schneider Str. 2, Wuerzburg, Germany.
authors.forename: Mathias T
authors.initials: MT
authors.lastname: Rosenfeldt
authors.affiliation: Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.
authors.forename: Jim
authors.initials: J
authors.lastname: O'Prey
authors.affiliation: Department of Pathology, University of Wuerzburg, Josef-Schneider Str. 2, Wuerzburg, Germany.
authors.forename: Lucia
authors.initials: L
authors.lastname: Flossbach
authors.affiliation: Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.
authors.forename: Colin
authors.initials: C
authors.lastname: Nixon
authors.affiliation: Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.
authors.forename: Jennifer P
authors.initials: JP
authors.lastname: Morton
authors.affiliation: Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.|Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G611BD, UK.
authors.forename: Owen J
authors.identifier: 0000-0001-9540-3010
authors.initials: OJ
authors.lastname: Sansom
authors.affiliation: Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.|Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G611BD, UK.
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Ryan
mesh_terms: D000818:Animals; D001343:Autophagy; D000071193:Autophagy-Related Protein 7 / Q000378:metabolism; D045744:Cell Line, Tumor; D006801:Humans; D051379:Mice; D051059:PTEN Phosphohydrolase / Q000172:deficiency* / Q000378:metabolism; D010190:Pancreatic Neoplasms / Q000201:enzymology* / Q000473:pathology*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism
chemical_list: D016159:Tumor Suppressor Protein p53; D051059:PTEN Phosphohydrolase; D000071193:Autophagy-Related Protein 7