title: Autoimmune Hepatitis Associated with Immune Thrombocytopenic Purpura.
abstract: Although autoimmune hepatitis (AIH) is frequently complicated with chronic thyroiditis or other autoimmune disorders, reports on its association with immune thrombocytopenic purpura (ITP) are scarce. We herein describe a case of AIH associated with ITP. A 75-year-old Japanese woman was admitted to our hospital due to increased aminotransferase levels and severe thrombocytopenia. Elevated serum immunoglobulin G (IgG) was detected, and tests for platelet-associated IgG and anti-nuclear antibody were positive. Following the diagnosis of AIH-associated ITP, prednisolone treatment of 0.6 mg/kg/day resulted in a decrease in the aminotransferase levels and an increased platelet count.
authors.affiliation: Department of Gastroenterology, National Hospital Organization, Shinshu Ueda Medical Center, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Ito
authors.forename: Kaname
authors.initials: K
authors.lastname: Yoshizawa
authors.forename: Kazuya
authors.initials: K
authors.lastname: Fujimori
authors.forename: Susumu
authors.initials: S
authors.lastname: Morita
authors.forename: Takashi
authors.initials: T
authors.lastname: Shigeno
authors.forename: Toshitaka
authors.initials: T
authors.lastname: Maejima
mesh_terms: D000368:Aged; D000974:Antibodies, Antinuclear / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D019693:Hepatitis, Autoimmune / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D011239:Prednisolone / Q000627:therapeutic use; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000974:Antibodies, Antinuclear; D005938:Glucocorticoids; D007074:Immunoglobulin G; D011239:Prednisolone