title: Uveal schwannoma in a brown-eyed dog.
abstract: An eleven-year-old, female spayed Boxer dog was diagnosed with a uveal schwannoma (formerly known as the spindle cell tumor of the blue-eyed dog or SCTBED) despite having a uniformly brown iris. The patient presented to emergency for ocular discomfort, and the right globe was subsequently enucleated due to glaucoma and submitted for histopathology. Upon histopathologic evaluation, a uveal schwannoma was diagnosed and confirmed with immunohistochemical staining. Complete metastatic evaluation 1 and 6 months after initial presentation did not reveal evidence of metastasis, and the dog remains systemically healthy. This case represents a unique variant of uveal schwannoma and is relevant because although the vast majority of these tumors occur in blue-eyed dogs, clinicians should not completely rule out this tumor as a differential based on the iris color.
authors.affiliation: Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: Todd L
authors.initials: TL
authors.lastname: Marlo
authors.affiliation: Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Giuliano
authors.affiliation: Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: Cecil P
authors.initials: CP
authors.lastname: Moore
authors.affiliation: School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
authors.forename: Gillian C
authors.initials: GC
authors.lastname: Shaw
authors.affiliation: School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
authors.forename: Leandro B C
authors.initials: LBC
authors.lastname: Teixeira
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology; D004285:Dogs; D005127:Eye Color; D005260:Female; D009442:Neurilemmoma / Q000473:pathology / Q000662:veterinary*; D014604:Uveal Neoplasms / Q000473:pathology* / Q000662:veterinary*
keywords: canine; intraocular; schwannoma; spindle cell tumor of blue-eyed dogs; tumor; uveal