title: Evolution of Gas Permeable Membranes for Extracorporeal Membrane Oxygenation.
abstract: Gas permeable membranes are a vital component of extracorporeal membrane oxygenation systems. Over more than half a century, membrane fabrication and packaging technology have progressed to enable safer and longer duration use of respiratory life support. Current research efforts seek to improve membrane efficiency and hemocompatibility, with the aim of producing smaller and more robust systems for ambulatory use. This review explores past and present innovations in oxygenator technology, suggesting possible applications of state-of-the-art membrane fabrication methods to address shortcomings of earlier concepts.
authors.affiliation: Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
authors.forename: Torin
authors.initials: T
authors.lastname: Yeager
authors.affiliation: Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
authors.forename: Shuvo
authors.initials: S
authors.lastname: Roy
mesh_terms: D000818:Animals; D004867:Equipment Design; D015199:Extracorporeal Membrane Oxygenation / Q000266:history / Q000295:instrumentation* / Q000379:methods; D005740:Gases / Q000737:chemistry; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D056656:Lab-On-A-Chip Devices / Q000266:history; D010107:Oxygenators, Membrane / Q000266:history; D010539:Permeability
chemical_list: D005740:Gases
keywords: Extracorporeal life support; Extracorporeal membrane oxygenation; Gas exchange; Membrane