title: Prevalence of and Factors Associated with Sarcopenia in Korean Cancer Survivors: Based on Data Obtained by the Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2011.
abstract: Using a representative dataset from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011, we analyzed anthropometric and dual-energy X-ray absorptiometry (DXA)-determined body composition findings for 493 cancer survivors (mean age a61.1 ± 12.6 years; 35.7% male). A much higher proportion of men (30.1%) than women (0.6%) met the criteria of sarcopenia. Subjects with a history of lung cancer, genitourinary cancer, or gastric cancer were prone to develop sarcopenia (31.6%, 26.3%, and 21.4%, respectively). Furthermore, sarcopenia was more prevalent among elderly (≥65 years; P < 0.001), those with a lower BMI level (<23 kg/m2; P < 0.001), heavy drinker (P = 0.012), or smoker (P < 0.001), and those with inadequate intakes of protein (P = 0.017) and vitamin A (P = 0.024). Multivariable logistic analyses revealed sarcopenia was significantly associated with male gender (odds ratio [OR], 68.14; 95% CI, 15.52-299.13), a BMI of <23 kg/m2(OR 35.93, 95% CI, 8.24-156.67), and inadequate protein intake (OR 3.07, 95% CI, 1.30-7.22); these factors are significant predictors of sarcopenia in Korean cancer survivors.
authors.affiliation: a Department of Radiology , Gachon University Gil Medical Center , Incheon , Republic of Korea.
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Kim
authors.affiliation: b Department of Food Science and Nutrition , Dankook University , Cheonan, Chungnam , Republic of Korea.
authors.forename: Kirang
authors.initials: K
authors.lastname: Kim
authors.affiliation: c Division of Hematology and Oncology, Department of Internal Medicine , Gachon University Gil Medical Center , Incheon , Republic of Korea.
authors.forename: Young Saing
authors.initials: YS
authors.lastname: Kim
authors.affiliation: c Division of Hematology and Oncology, Department of Internal Medicine , Gachon University Gil Medical Center , Incheon , Republic of Korea.
authors.forename: Hee Kyung
authors.initials: HK
authors.lastname: Ahn
authors.affiliation: a Department of Radiology , Gachon University Gil Medical Center , Incheon , Republic of Korea.
authors.forename: Yu Mi
authors.initials: YM
authors.lastname: Jeong
authors.affiliation: a Department of Radiology , Gachon University Gil Medical Center , Incheon , Republic of Korea.
authors.forename: Jeong Ho
authors.initials: JH
authors.lastname: Kim
authors.affiliation: d Department of Occupational and Environmental Medicine , Gachon University Gil Medical Center , Incheon , Republic of Korea.
authors.forename: Won-Jun
authors.initials: WJ
authors.lastname: Choi
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D000886:Anthropometry; D044466:Asian People; D001823:Body Composition; D000073116:Cancer Survivors; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D009749:Nutrition Surveys; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D055948:Sarcopenia / Q000453:epidemiology*; D014807:Vitamin D / Q000031:analogs & derivatives / Q000097:blood
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D