title: Prevalence and Correlates of Metabolic Syndrome in Chinese Children: The China Health and Nutrition Survey.
abstract: Metabolic syndrome (MetS) is generally defined as a cluster of metabolically related cardiovascular risk factors which are often associated with the condition of insulin resistance, elevated blood pressure, and abdominal obesity. During the past decades, MetS has become a major public health issue worldwide in both adults and children. In this study, data from the China Health and Nutrition Surveys (CHNS) was used to assess the prevalence of MetS based on both the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII) guidelines and the International Diabetes Federation (IDF) criteria, and to evaluate its possible correlates. A total of 831 children aged 7-18 years were included in this study, and 28 children were classified as having MetS as defined by the modified NCEP-ATPIII definition, which yielded an overall prevalence of 3.37%. Elevated blood pressure was the most frequent MetS component. The results of logistic regression models revealed that increased body mass index (BMI), hyperuricemia, and insulin resistance (IR) were all associated with the presence of MetS. To conclude, our study revealed the prevalence of MetS in Chinese children at the national level. Further large-scale studies are still needed to identify better MetS criteria in the general paediatric population in China.
authors.affiliation: Department of Child, Adolescent and Women's Health, School of Public Health, Peking University, Beijing 100191, China. peigesong@hsc.pku.edu.cn.|Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK. peigesong@hsc.pku.edu.cn.
authors.forename: Peige
authors.initials: P
authors.lastname: Song
authors.affiliation: Division of Medicine, School of Life and Medical Science, University College London, London WC1E 6BT, UK. rmhajyy@ucl.ac.uk.
authors.forename: Jinyue
authors.initials: J
authors.lastname: Yu
authors.affiliation: Department of Child, Adolescent and Women's Health, School of Public Health, Peking University, Beijing 100191, China. changxl_echo@163.com.
authors.forename: Xinlei
authors.initials: X
authors.lastname: Chang
authors.affiliation: Department of Child, Adolescent and Women's Health, School of Public Health, Peking University, Beijing 100191, China. 18354226871@163.com.
authors.forename: Manli
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Child, Adolescent and Women's Health, School of Public Health, Peking University, Beijing 100191, China. anlinbjmu@163.com.
authors.forename: Lin
authors.initials: L
authors.lastname: An
mesh_terms: D000293:Adolescent; D044466:Asian People; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D001835:Body Weight; D002648:Child; D002681:China / Q000453:epidemiology; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006306:Health Surveys; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000453:epidemiology*; D007328:Insulin / Q000097:blood; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000453:epidemiology*; D009749:Nutrition Surveys; D015995:Prevalence; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D007328:Insulin; D014280:Triglycerides
keywords: China; children; epidemiology; metabolic syndrome