title: Stiffer double-stranded DNA in two-dimensional confinement due to bending anisotropy.
abstract: Using analytical approach and Monte Carlo (MC) simulations, we study the elastic behavior of the intrinsically twisted elastic ribbons with bending anisotropy, such as double-stranded DNA (dsDNA), in two-dimensional (2D) confinement. We show that, due to the bending anisotropy, the persistence length of dsDNA in 2D conformations is always greater than three-dimensional (3D) conformations. This result is in consistence with the measured values for DNA persistence length in 2D and 3D in equal biological conditions. We also show that in two dimensions, an anisotropic, intrinsically twisted polymer exhibits an implicit twist-bend coupling, which leads to the transient curvature increasing with a half helical turn periodicity along the bent polymer.
authors.affiliation: Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, Tehran, Iran.
authors.forename: H
authors.initials: H
authors.lastname: Salari
authors.affiliation: Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands.
authors.forename: B
authors.initials: B
authors.lastname: Eslami-Mossallam
authors.affiliation: Institute of Complex Systems (ICS-2), Forschungszentrum Jülich, Wilhelm-Johnen-Straße, 52425 Jülich, Germany.
authors.forename: H F
authors.initials: HF
authors.lastname: Ranjbar
authors.affiliation: Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, Tehran, Iran and School of Nano Science, Institute for Research in Fundamental Sciences (IPM), Tehran 19395-5531, Iran.
authors.forename: M R
authors.initials: MR
authors.lastname: Ejtehadi
mesh_terms: D016880:Anisotropy; D003198:Computer Simulation; D004247:DNA / Q000737:chemistry*; D008958:Models, Molecular; D009010:Monte Carlo Method; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA