title: A Non-invasive 24 Hours Stabilization of Duodenal Ulcer Perforation by a Combination Regimen.
abstract: Surgical repair of perforated gastroduodenal ulcer has been extensively practiced in emergency clinical situations. Non-invasive conservation treatment is regaining the attention towards management of such ulcers. We report the case of a 50-year-old male smoker who presented in the emergency unit with acute generalized abdominal pain and guarding in the epigastric and right upper quadrant region. He is a known regular user of over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDS) for more than 10 years for his osteoarthiritis and myalgias. A differential diagnosis of gastritis and duodenal perforation was made owing to the symptoms and long usage of NSAIDs. He was managed with an intravenous proton pump inhibitor and intravenous antibiotics. This therapy lead to stabilization of the clinical symptoms as well as laboratory and imaging studies.
authors.affiliation: Surgery, Fatima Memorial Hospital.
authors.forename: Ahsan
authors.initials: A
authors.lastname: Zil-E-Ali
authors.affiliation: Department of General Surgery, Postgraduate Trainee, Ghurki Trust Hospital, Lahore Medical & Dental College.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Bin Shafique
authors.affiliation: Department of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
authors.forename: Salman
authors.initials: S
authors.lastname: Assad
authors.affiliation: Biochemistry, Fatima Memorial Hospital.
authors.forename: Hammad
authors.initials: H
authors.lastname: Ali
authors.affiliation: Department of Medicine, Shifa International Hospital, Islamabad, Pakistan.
authors.forename: Usman
authors.initials: U
authors.lastname: Ghani
keywords: duodenal ulcer; non-invasive management; perforated ulcer