title: Does the addition of salpingectomy or fimbriectomy to hysterectomy in premenopausal patients compromise ovarian reserve? A prospective study.
abstract: OBJECTIVE
  To evaluate changes in ovarian reserve in patients following hysterectomy, with or without bilateral salpingectomy or fimbriectomy.
  
  
  METHODS
  Open-label, prospective cohort trial of patients undergoing hysterectomy for benign uterine indications. Levels of follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and ultrasonic measures of peak systolic flow velocity/diastolic velocity (S/D) ratio and resistance index (RI) in the ovarian artery were taken from patients before and 6 weeks after hysterectomy, hysterectomy+salpingectomy or hysterectomy+fimbriectomy.
  
  
  RESULTS
  The study period was from November 2011 to May 2014. Sixty patients were included in the final analysis, after two patients were lost to follow-up and one patient underwent bilateral oophorectomy. Of these 60 patients, 16 underwent hysterectomy alone (control group), and 44 were included in the study group (22 patients underwent hysterectomy+fimbriectomy and 22 patients underwent hysterectomy+salpingectomy). The mean age of patients was 46 years (standard deviation 4.07 years). Between-group dfferences in FSH, AMH, ovarian volume, ovarian artery S/D ratio and ovarian artery RI were not significant.
  
  
  CONCLUSIONS
  The addition of salpingectomy or fimbriectomy to routine hysterectomy in premenopausal patients does not diminish ovarian reserve.
authors.affiliation: Department of Obstetrics and Gynaecology, Kaplan Medical Centre, Rehovot, Israel. Electronic address: yaelnaa@gmail.com.
authors.forename: Y
authors.initials: Y
authors.lastname: Naaman
authors.affiliation: Department of Obstetrics and Gynaecology, Kaplan Medical Centre, Rehovot, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Hazan
authors.affiliation: Department of Obstetrics and Gynaecology, Kaplan Medical Centre, Rehovot, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Gillor
authors.affiliation: Department of Obstetrics and Gynaecology, Kaplan Medical Centre, Rehovot, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Marciano
authors.affiliation: Microbiology Laboratory, Kaplan Medical Center, Rehovot, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Bardenstein
authors.affiliation: Department of Obstetrics and Gynaecology, Kaplan Medical Centre, Rehovot, Israel.
authors.forename: Z
authors.initials: Z
authors.lastname: Shoham
authors.affiliation: Department of Obstetrics and Gynaecology, Kaplan Medical Centre, Rehovot, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Ben-Arie
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D008875:Middle Aged; D065851:Ovarian Reserve; D017697:Premenopause; D011446:Prospective Studies; D058994:Salpingectomy / Q000009:adverse effects*
keywords: Fimbriectomy; Hysterectomy; Menopause; Ovarian reserve; Salpingectomy