title: Autosomal SNPs study of a population sample from Southern Portugal and from a sample of immigrants from Guinea-Bissau residing in Portugal.
abstract: In recent years, autosomal single nucleotide polymorphisms (SNPs) have been comprehensively investigated in forensic research due to their usefulness in certain circumstances in complementing short tandem repeats (STRs) analysis, or even for use on their own when analysis of STRs fails. However, as with STRs, in order to properly use SNP markers in forensic casuistic we need to understand the population and forensic parameters in question. As a result of Portugal's colonial history during the time of empire, and the subsequent process of decolonization, some African individuals migrated to Portugal, giving rise to large African and African-descendent communities. One of these groups is the community originating from Guinea-Bissau, that in 2014, was enumerated to consist of more than 17,700 individuals with official residency status, more than the third major city of Guinea-Bissau. In order to study the population and forensic parameters mentioned above for the two populations important to our casuistic, a total of 142 unrelated individuals from the South of Portugal and 90 immigrants from Guinea-Bissau (equally non related and all residing in Portugal) were typed with SNaPshot™ assay for all 52 loci included in the SNPforID 52plex.
authors.affiliation: INMLCF - National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal; University of Lisbon, Faculty of Sciences, Campo Grande, 1749-016 Lisboa, Portugal; CENCIFOR - Forensic Sciences Centre, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal; CESAM - Centre for Environmental and Marine Studies, Pólo de Lisboa, Edifício C2, Campo Grande, 1749-016 Lisboa, Portugal. Electronic address: paulo.a.dario@inmlcf.mj.pt.
authors.forename: Paulo
authors.initials: P
authors.lastname: Dario
authors.affiliation: INMLCF - National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal; University of Lisbon, Faculty of Sciences, Campo Grande, 1749-016 Lisboa, Portugal; CESAM - Centre for Environmental and Marine Studies, Pólo de Lisboa, Edifício C2, Campo Grande, 1749-016 Lisboa, Portugal.
authors.forename: Ana Rita
authors.initials: AR
authors.lastname: Oliveira
authors.affiliation: INMLCF - National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal; CENCIFOR - Forensic Sciences Centre, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal.
authors.forename: Teresa
authors.initials: T
authors.lastname: Ribeiro
authors.affiliation: INMLCF - National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal; CENCIFOR - Forensic Sciences Centre, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal.
authors.forename: Maria João
authors.initials: MJ
authors.lastname: Porto
authors.affiliation: University of Lisbon, Faculty of Sciences, Campo Grande, 1749-016 Lisboa, Portugal; CESAM - Centre for Environmental and Marine Studies, Pólo de Lisboa, Edifício C2, Campo Grande, 1749-016 Lisboa, Portugal.
authors.forename: Deodália
authors.initials: D
authors.lastname: Dias
authors.affiliation: INMLCF - National Institute of Legal Medicine and Forensic Sciences, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal; CENCIFOR - Forensic Sciences Centre, Largo da Sé Nova, s/n, 3000-213 Coimbra, Portugal; University of Coimbra, Faculty of Medicine, Rua Larga, 3004-504 Coimbra, Portugal.
authors.forename: Francisco
authors.initials: F
authors.lastname: Corte Real
mesh_terms: D016172:DNA Fingerprinting; D054242:Emigrants and Immigrants; D005787:Gene Frequency; D005828:Genetics, Population; D006169:Guinea-Bissau; D006801:Humans; D018895:Microsatellite Repeats; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011174:Portugal; D060888:Real-Time Polymerase Chain Reaction
keywords: 52plex; DNA frequency estimate; Genetic distance; Guinea-Bissau; SNP; South of Portugal