title: Is It Time to Include CT "Reverse Halo Sign" and qPCR Targeting Mucorales in Serum to EORTC-MSG Criteria for the Diagnosis of Pulmonary Mucormycosis in Leukemia Patients?
abstract: In 23 leukemia patients with proven (n = 17) or possible (n = 6) pulmonary mucormycosis (PM), the presence of reversed halo sign on computed tomography was strongly associated with the positivity of quantitative polymerase chain reaction assays targeting Mucorales in the serum, confirming the value of these two tools for the diagnosis of PM in this setting.
authors.affiliation: Department of Clinical Haematology, University Hospital, Dijon; Inserm Unit 866, LabEx Team, Dijon School of Medicine.
authors.forename: Denis
authors.initials: D
authors.lastname: Caillot
authors.affiliation: Mycology and Parasitology Department , University Hospital , Dijon.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Valot
authors.affiliation: Department of Clinical Haematology , University Hospital , Dijon.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Lafon
authors.affiliation: Mycology and Parasitology Department, University Hospital, Dijon; Bourgogne Franche-Comté University, Agrosup Dijon, UMR PAM, Team Vin, Aliment, Microbiologie, Stress.
authors.forename: Louise
authors.initials: L
authors.lastname: Basmaciyan
authors.affiliation: Department of Clinical Haematology, University Hospital, Dijon; Inserm Unit 866, LabEx Team, Dijon School of Medicine.
authors.forename: Marie Lorraine
authors.initials: ML
authors.lastname: Chretien
authors.affiliation: Mycology and Parasitology Department, University Hospital, Dijon; Bourgogne Franche-Comté University, Agrosup Dijon, UMR PAM, Team Vin, Aliment, Microbiologie, Stress.
authors.forename: Marc
authors.initials: M
authors.lastname: Sautour
authors.affiliation: Chrono-Environnement UMR, 6249 CNRS, Bourgogne Franche-Comté University, Besançon; Parasitology-Mycology Department, University Hospital, Besançon, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Million
authors.affiliation: Department of Clinical Haematology, University Hospital, Dijon; Inserm Unit 866, LabEx Team, Dijon School of Medicine.
authors.forename: Caroline
authors.initials: C
authors.lastname: Legouge
authors.affiliation: Department of Clinical Haematology , University Hospital , Dijon.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Payssot
authors.affiliation: Mycology and Parasitology Department, University Hospital, Dijon; Bourgogne Franche-Comté University, Agrosup Dijon, UMR PAM, Team Vin, Aliment, Microbiologie, Stress.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Dalle
keywords: early diagnosis; leukemia; pulmonary mucormycosis; quantitative polymerase chain reaction; reversed halo sign