title: Implementing Genomic Clinical Decision Support for Drug-Based Precision Medicine.
abstract: The explosive growth of patient-specific genomic information relevant to drug therapy will continue to be a defining characteristic of biomedical research. To implement drug-based personalized medicine (PM) for patients, clinicians need actionable information incorporated into electronic health records (EHRs). New clinical decision support (CDS) methods and informatics infrastructure are required in order to comprehensively integrate, interpret, deliver, and apply the full range of genomic data for each patient.
authors.affiliation: Department of Health Sciences Research, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: R R
authors.initials: RR
authors.lastname: Freimuth
authors.affiliation: Department of Pharmacy, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: C M
authors.initials: CM
authors.lastname: Formea
authors.affiliation: Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Hoffman
authors.affiliation: Department of Pharmacy, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: E
authors.initials: E
authors.lastname: Matey
authors.affiliation: Department of Biomedical Informatics and Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
authors.forename: J F
authors.initials: JF
authors.lastname: Peterson
authors.affiliation: Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Boyce
mesh_terms: D030541:Databases, Genetic / Q000639:trends; D020000:Decision Support Systems, Clinical / Q000639:trends; D057286:Electronic Health Records / Q000639:trends; D023281:Genomics / Q000379:methods* / Q000639:trends; D006801:Humans; D057285:Precision Medicine / Q000379:methods* / Q000639:trends