title: Staging Evaluation and Response Criteria Harmonization (SEARCH) for Childhood, Adolescent and Young Adult Hodgkin Lymphoma (CAYAHL): Methodology statement.
abstract: International harmonization of staging evaluation and response criteria is needed for childhood, adolescence, and young adulthood Hodgkin lymphoma. Two Hodgkin lymphoma protocols from cooperative trials in Europe and North America were compared for areas in need of harmonization, and an evidence-based approach is currently underway to harmonize staging and response evaluations with a goal to enhance comparisons, expedite identification of effective therapies, and aid in the approval process for new agents by regulatory agencies.
authors.affiliation: Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Jamie E
authors.initials: JE
authors.lastname: Flerlage
authors.affiliation: Roswell Park Cancer Institute, University of Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York.
authors.forename: Kara M
authors.initials: KM
authors.lastname: Kelly
authors.affiliation: Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
authors.forename: Auke
authors.initials: A
authors.lastname: Beishuizen
authors.affiliation: Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
authors.forename: Steve
authors.initials: S
authors.lastname: Cho
authors.affiliation: University of Illinois College of Medicine, Peoria, Illinois.
authors.forename: Pedro A
authors.initials: PA
authors.lastname: De Alarcon
authors.affiliation: Klinik für Strahlenheilkunde, Universitätsklinik Freiburg, Freiburg, Germany.
authors.forename: Ute
authors.initials: U
authors.lastname: Dieckmann
authors.affiliation: Division of Pediatric Hematology Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Drachtman
authors.affiliation: Department of Radiation Oncology, University of Florida, Gainesville, Florida.
authors.forename: Bradford S
authors.initials: BS
authors.lastname: Hoppe
authors.affiliation: University of Memphis School of Health Studies, Memphis, Tennessee.
authors.forename: Scott C
authors.initials: SC
authors.lastname: Howard
authors.affiliation: Department of Diagnostic Imaging, University of Tennessee Health Sciences Center, Memphis, Tennessee.
authors.forename: Sue C
authors.initials: SC
authors.lastname: Kaste
authors.affiliation: Department of Nuclear Medicine, University Hospital of Leipzig, Leipzig, Germany.
authors.forename: Regine
authors.initials: R
authors.lastname: Kluge
authors.affiliation: Department of Nuclear Medicine, University Hospital of Leipzig, Leipzig, Germany.
authors.forename: Lars
authors.initials: L
authors.lastname: Kurch
authors.affiliation: Department of Paediatric Haematology & Oncology, Hôpital Trousseau AP-HP & Université Pierre et Marie Curie, Paris, France.
authors.forename: Judith
authors.initials: J
authors.lastname: Landman-Parker
authors.affiliation: Division of Pediatric Hematology Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey.
authors.forename: Jocelyn
authors.initials: J
authors.lastname: Lewis
authors.affiliation: Division of Pediatric Hematology-Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Link
authors.affiliation: Rhode Island Hospital/Warren Alpert Medical School at Brown University, Providence, Rhode Island.
authors.forename: Kathleen
authors.initials: K
authors.lastname: McCarten
authors.affiliation: Division of Haematology/Oncology, Department of Paediatrics, SickKids Hospital and University of Toronto, Toronto, Canada.
authors.forename: Angela
authors.initials: A
authors.lastname: Punnett
authors.affiliation: University Clinic Halle (Saale), Halle, Germany.
authors.forename: Dietrich
authors.initials: D
authors.lastname: Stoevesandt
authors.affiliation: Department of Radiology, Boston Children's Hospital Dana-Farber Cancer Institute, Boston, Massachusetts.
authors.forename: Stephan D
authors.initials: SD
authors.lastname: Voss
authors.affiliation: Royal Hospital for Sick Children, Edinburgh, Scotland, UK.
authors.forename: William Hamish
authors.initials: WH
authors.lastname: Wallace
authors.affiliation: Department of Pädiatrische Hämatologie und Onkologie, Zentrum für Kinderheilkunde der Justus-Liebig-Universität Gießen, Gießen, Germany.|Medical Faculty, Martin-Luther-University of Halle-Wittenberg, Halle, Germany.
authors.forename: Christine
authors.initials: C
authors.lastname: Mauz-Körholz
authors.affiliation: Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Monika L
authors.initials: ML
authors.lastname: Metzger
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008297:Male; D009367:Neoplasm Staging / Q000379:methods* / Q000592:standards*; D055815:Young Adult
keywords: Hodgkin lymphoma; cancer; international; lymphoma; pediatric; pediatric oncology