title: A novel kindred with inherited STAT2 deficiency and severe viral illness.
authors.affiliation: Department of Immunology and Microbiology, Experimental Laboratory Immunology, Childhood Immunology, Katholieke Universiteit (KU) Leuven, Leuven, Flanders, Belgium.
authors.forename: Leen
authors.initials: L
authors.lastname: Moens
authors.affiliation: Department of Immunology and Microbiology, Autoimmune Genetics Laboratory, Vlaams Instituut Biotechnologie and KU Leuven, Leuven, Flanders, Belgium.
authors.forename: Lien
authors.initials: L
authors.lastname: Van Eyck
authors.affiliation: Department of Immunology and Microbiology, Rega Institute, Laboratory Virology and Chemotherapy, KU Leuven, Leuven, Flanders, Belgium.
authors.forename: Dirk
authors.initials: D
authors.lastname: Jochmans
authors.affiliation: Department of Immunology and Microbiology, Rega Institute, Laboratory of Immunobiology, KU Leuven, Leuven, Flanders, Belgium.
authors.forename: Tania
authors.initials: T
authors.lastname: Mitera
authors.affiliation: Department of Immunology and Microbiology, Experimental Laboratory Immunology, Childhood Immunology, Katholieke Universiteit (KU) Leuven, Leuven, Flanders, Belgium.
authors.forename: Glynis
authors.initials: G
authors.lastname: Frans
authors.affiliation: Department of Immunology and Microbiology, Experimental Laboratory Immunology, Childhood Immunology, Katholieke Universiteit (KU) Leuven, Leuven, Flanders, Belgium.
authors.forename: Xavier
authors.initials: X
authors.lastname: Bossuyt
authors.affiliation: Department of Immunology and Microbiology, Rega Institute, Laboratory of Immunobiology, KU Leuven, Leuven, Flanders, Belgium.
authors.forename: Patrick
authors.initials: P
authors.lastname: Matthys
authors.affiliation: Department of Immunology and Microbiology, Rega Institute, Laboratory Virology and Chemotherapy, KU Leuven, Leuven, Flanders, Belgium.
authors.forename: Johan
authors.initials: J
authors.lastname: Neyts
authors.affiliation: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.
authors.forename: Michael
authors.initials: M
authors.lastname: Ciancanelli
authors.affiliation: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale-U1163, Paris, France; Paris Descartes University, Imagine Institute, Paris, France.
authors.forename: Shen-Ying
authors.initials: SY
authors.lastname: Zhang
authors.affiliation: Laboratory for Molecular Virology and Gene Therapy, KU Leuven, Leuven, Flanders, Belgium.
authors.forename: Rik
authors.initials: R
authors.lastname: Gijsbers
authors.affiliation: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale-U1163, Paris, France; Pediatric Hematology and Immunology Unit, Assistance Publique-Hôpitaux de Paris, Necker Hospital for Sick Children, Paris, France; Paris Descartes University, Imagine Institute, Paris, France; Howard Hughes Medical Institute, New York, NY.
authors.forename: Jean-Laurent
authors.initials: JL
authors.lastname: Casanova
authors.affiliation: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale-U1163, Paris, France; Paris Descartes University, Imagine Institute, Paris, France.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Boisson-Dupuis
authors.affiliation: Department of Immunology and Microbiology, Childhood Immunology, Leuven, Flanders, Belgium; Department of Pediatrics, University Hospitals Leuven and KU Leuven, Leuven, Flanders, Belgium. Electronic address: Isabelle.Meyts@uzleuven.be.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Meyts
authors.affiliation: Department of Immunology and Microbiology, Autoimmune Genetics Laboratory, Vlaams Instituut Biotechnologie and KU Leuven, Leuven, Flanders, Belgium. Electronic address: adrian.liston@vib.be.
authors.forename: Adrian
authors.initials: A
authors.lastname: Liston
mesh_terms: D000483:Alleles; D005260:Female; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008297:Male; D010375:Pedigree; D050795:STAT2 Transcription Factor / Q000172:deficiency*; D012720:Severity of Illness Index; D014777:Virus Diseases / Q000175:diagnosis* / Q000209:etiology*; D000073336:Whole Genome Sequencing
chemical_list: D050795:STAT2 Transcription Factor