title: Prevalence of oral manifestations in children and adolescents with cancer submitted to chemotherapy.
abstract: BACKGROUND
  Oral complications may be observed during chemotherapy and are important side effects that may directly affect the anticancer treatment, even causing septicaemia in some cases. This research was done in order to evaluate changes in oral lesions during follow-up of children and adolescents in chemotherapy at Hospital Estadual Infantil Nossa Senhora da Glória (HEINSG).
  
  
  METHODS
  The study design was longitudinal, 45 patients were evaluated and monitored for 1 month after the initiation of chemotherapy. Twenty-eight patients were male and 17 female, ranging from 3 months to 18 years old.
  
  
  RESULTS
  The results show an increase in the number of mucositis cases and a decrease in xerostomia cases after the initiation of treatment, and other oral lesions were also found in low numbers.
  
  
  CONCLUSIONS
  It is possible to avoid oral complications by maintaining a good oral health, and reducing infectious outbreaks. It is also feasible to obtain an early diagnosis of, and treat these oral complications, preventing them from following a more severe clinical course that may negatively affect the individual's treatment. This outcome requires the presence of a dental surgeon on the multidisciplinary cancer treatment team.
authors.affiliation: Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, ES, 29043-900, Brazil. deisebergervelten@yahoo.com.br.
authors.forename: Deise Berger
authors.initials: DB
authors.lastname: Velten
authors.affiliation: Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, ES, 29043-900, Brazil.
authors.forename: Eliana
authors.initials: E
authors.lastname: Zandonade
authors.affiliation: Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, ES, 29043-900, Brazil.
authors.forename: Maria Helena
authors.initials: MH
authors.lastname: Monteiro de Barros Miotto
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004408:Dysgeusia / Q000139:chemically induced; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D009059:Mouth Diseases / Q000139:chemically induced*; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy; D009909:Oral Health; D015995:Prevalence; D013280:Stomatitis / Q000139:chemically induced; D014987:Xerostomia / Q000139:chemically induced
chemical_list: D000970:Antineoplastic Agents
keywords: Chemotherapy; Oncology; Oral manifestations