title: A Step-by-Step Clinical Approach for the Management of Neuroendocrine Tumours.
abstract: Neuroendocrine tumours (NET) are rare neoplasms, but the incidence is permanently increasing. Most of the NETs are slow proliferating and clinically silent, and for that reason, they are often diagnosed at a stage with advanced disease. The complexity and diversity of the NET-biology require the treatment of patients in specialised centres to guarantee a qualified, multidisciplinary treatment planning. At our institution, we developed an interdisciplinary model for the assessment and treatment of NET. The aim was to adapt the guidelines to the clinical practice, exchange of current knowledge, and a tailored approach to the individual patient. In our team are included medical professionals from pathology, radiology, oncology, gastroenterology, oncological surgery, and nuclear medicine. In this paper, we describe step-by-step a procedural algorithm for the management of patients with neuroendocrine tumours, focusing on midgut-NETs in terms of therapy.
authors.affiliation: Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Yordanova
authors.affiliation: Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Ahmadzadehfar
authors.affiliation: Department of Internal Medicine 1, University Hospital Bonn, Bonn, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Gonzalez-Carmona
authors.affiliation: Department of Internal Medicine 1, University Hospital Bonn, Bonn, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Strassburg
authors.affiliation: Department of Internal Medicine 3, University Hospital Bonn, Bonn, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Mayer
authors.affiliation: Department of Internal Medicine 3, University Hospital Bonn, Bonn, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Feldmann
authors.affiliation: Department of Internal Medicine 3, University Hospital Bonn, Bonn, Germany.
authors.forename: I
authors.initials: I
authors.lastname: Schmidt-Wolf
authors.affiliation: Department of Surgery, University Hospital Bonn, Bonn, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Lingohr
authors.affiliation: Department of Radiology, University Hospital Bonn, Bonn, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Fischer
authors.affiliation: Department of Pathology, University Hospital Bonn, Bonn, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Kristiansen
authors.affiliation: Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Essler
mesh_terms: D003952:Diagnostic Imaging; D005500:Follow-Up Studies; D006801:Humans; D009367:Neoplasm Staging; D018358:Neuroendocrine Tumors / Q000145:classification / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*