title: Levels of miRNA and Hormones in Thoracic Duct Lymph in Rats with Experimental Breast Cancer Induced by N-Methyl-N-Nitrosourea.
abstract: We studied hormone levels in the thoracic duct lymph and expression of miRNA involved in the pathogenesis of breast cancer induced in rats by intramammary injection of N-methyl-Nnitrosourea. The correlations between miRNA expression and hormone levels depended on the type of treatment.
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia. aplykov2@mail.ru.
authors.forename: A P
authors.initials: AP
authors.lastname: Lykov
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Kabakov
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Kazakov
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Bondarenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Poveshchenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: T V
authors.initials: TV
authors.lastname: Raiter
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: A F
authors.initials: AF
authors.lastname: Poveshchenko
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: D N
authors.initials: DN
authors.lastname: Strunkin
authors.affiliation: Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Konenkov
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology; D002273:Carcinogens / Q000633:toxicity; D003520:Cyclophosphamide / Q000494:pharmacology; D004958:Estradiol / Q000378:metabolism; D005260:Female; D005472:Fluorouracil / Q000494:pharmacology; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D007986:Luteinizing Hormone / Q000378:metabolism; D008196:Lymph / Q000737:chemistry*; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D008727:Methotrexate / Q000494:pharmacology; D008770:Methylnitrosourea / Q000633:toxicity; D035683:MicroRNAs / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013897:Thoracic Duct / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D013954:Thyroglobulin / Q000378:metabolism
chemical_list: D002273:Carcinogens; D035683:MicroRNAs; D004958:Estradiol; D008770:Methylnitrosourea; D003520:Cyclophosphamide; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013954:Thyroglobulin; D005472:Fluorouracil; D008727:Methotrexate
keywords: N-methyl-N-nitrosourea; breast cancer; hormones; lymph; miRNA