title: Major Change in Body Weight over 5 Years and Total Sleep Time: Investigation of Effect Modification by Sex and Obesity in a Large e-Cohort.
abstract: We assessed the association of long-term weight change ≥5 kg with total sleep time (TST), investigating effect modification by sex and overweight/obesity.
  
  
  
  In a cross-sectional context, we studied 41,610 adults from the general population-based NutriNet-Santé e-cohort. A sleep questionnaire was self-administered in 2014. It included sleep logs for the estimation of average TST at night, and items for the calculation of major weight change as experienced over the previous 5 years. We fit multivariate polytomous logistic regression models.
  
  
  
  Overall, women with major weight loss had an increased likelihood of short TST (≤6 h) when compared with women with stable weight (OR = 1.15, 95% CI: 1.05-1.25). Individuals with major weight gain had an increased likelihood of short TST compared with their counterparts with stable weight (men: OR = 1.20, 95% CI: 1.05-1.37; women: OR = 1.24, 95% CI: 1.15-1.33). Men with major weight gain were less likely to report long TST compared with men with stable weight (OR = 0.83, 95% CI: 0.70-0.97). Overweight or obesity did not moderate the associations.
  
  
  
  The study advances knowledge in the fields of public health and nutrition by providing some evidence of a sex-specific association of major weight change with both short and long TST. These associations merit future investigation in a longitudinal context with repeated, objective measures of both weight and sleep time, while applying more stringent interaction test criteria and accounting for changes in health behaviors.
authors.affiliation: Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), Centre de Recherche en Epidémiologie et Statistiques, Inserm U1153, Inra U1125, Cnam, COMUE Sorbonne Paris Cité, Université Paris 13, F-93017, Bobigny, France. v.andreeva@eren.smbh.univ-paris13.fr.
authors.forename: Valentina A
authors.initials: VA
authors.lastname: Andreeva
authors.affiliation: Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), Centre de Recherche en Epidémiologie et Statistiques, Inserm U1153, Inra U1125, Cnam, COMUE Sorbonne Paris Cité, Université Paris 13, F-93017, Bobigny, France.
authors.forename: Marion J
authors.initials: MJ
authors.lastname: Torres
authors.affiliation: Sorbonne Paris Cité, AP-HP Hôtel-Dieu, Centre du Sommeil et de la Vigilance et EA7330 VIFASOM, Université Paris Descartes, F-75004, Paris, France.
authors.forename: Damien
authors.initials: D
authors.lastname: Léger
authors.affiliation: Sorbonne Paris Cité, AP-HP Hôtel-Dieu, Centre du Sommeil et de la Vigilance et EA7330 VIFASOM, Université Paris Descartes, F-75004, Paris, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Bayon
authors.affiliation: Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), Centre de Recherche en Epidémiologie et Statistiques, Inserm U1153, Inra U1125, Cnam, COMUE Sorbonne Paris Cité, Université Paris 13, F-93017, Bobigny, France.
authors.forename: Paloma
authors.initials: P
authors.lastname: Gonzalez
authors.affiliation: Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), Centre de Recherche en Epidémiologie et Statistiques, Inserm U1153, Inra U1125, Cnam, COMUE Sorbonne Paris Cité, Université Paris 13, F-93017, Bobigny, France.
authors.forename: Fabien Szabo
authors.initials: FS
authors.lastname: de Edelenyi
authors.affiliation: Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), Centre de Recherche en Epidémiologie et Statistiques, Inserm U1153, Inra U1125, Cnam, COMUE Sorbonne Paris Cité, Université Paris 13, F-93017, Bobigny, France.|Département de Santé Publique, Hôpital Avicenne, F-93017, Bobigny, France.
authors.forename: Serge
authors.initials: S
authors.lastname: Hercberg
authors.affiliation: Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), Centre de Recherche en Epidémiologie et Statistiques, Inserm U1153, Inra U1125, Cnam, COMUE Sorbonne Paris Cité, Université Paris 13, F-93017, Bobigny, France.
authors.forename: Pilar
authors.initials: P
authors.lastname: Galan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D015438:Health Behavior; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology*; D050177:Overweight / Q000453:epidemiology*; D012890:Sleep / Q000502:physiology*; D011795:Surveys and Questionnaires; D015430:Weight Gain / Q000502:physiology*; D055815:Young Adult
keywords: Body mass index; E-cohort; General population; Health behavior; Sleep; Weight change