title: Selective synthesis of thioethers in the presence of a transition-metal-free solid Lewis acid.
abstract: The synthesis of thioethers starting from alcohols and thiols in the presence of amorphous solid acid catalysts is reported. A silica alumina catalyst with a very low content in alumina gave excellent results in terms of both activity and selectivity also under solvent-free conditions. The reaction rate follows the electron density of the carbinol atom in the substrate alcohol and yields up to 99% and can be obtained for a wide range of substrates under mild reaction conditions.
authors.affiliation: CNR ISTM, via C. Golgi 19, 20133 Milano, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Santoro
authors.affiliation: CNR ISTM, via C. Golgi 19, 20133 Milano, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Mariani
authors.affiliation: CNR ISTM, via C. Golgi 19, 20133 Milano, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Zaccheria
authors.affiliation: CNR ISTM, via C. Golgi 19, 20133 Milano, Italy.
authors.forename: Rinaldo
authors.initials: R
authors.lastname: Psaro
authors.affiliation: CNR ISTM, via C. Golgi 19, 20133 Milano, Italy.
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Ravasio
keywords: S-alkylation; no solvent; solid acids; thioethers; transition-metal-free