title: Locoregional control of tongue base adenoid cystic carcinoma with primary resection and radial forearm free flap reconstruction.
abstract: Adenoid cystic carcinoma of the minor salivary glands can be challenging and marked by high rates of local recurrence despite appropriate surgical resection. Management of this pathology in the base of the tongue is particularly difficult given the poor functional outcomes traditionally associated with an aggressive surgical approach. This article presents a case series of patients who underwent up-front surgical resection followed by free tissue transfer reconstruction. A retrospective analysis was performed of patients with adenoid cystic carcinoma of the base of the tongue who underwent composite resection and reconstruction with a radial forearm free flap. Three patients met inclusion criteria and underwent analysis. All patients achieved locoregional control after at least 4 years of surveillance. In addition, all patients were decannulated and were swallowing without the need for gastrostomy tube feeding. This series demonstrates that for select patients with adenoid cystic carcinoma of the base of the tongue, excellent locoregional control can be achieved with acceptable functional outcomes and prolonged survival when appropriate reconstructive measures are employed.
authors.affiliation: Department of Otolaryngology, Lahey Clinic, Boston, MA, USA.
authors.forename: Bharat B
authors.initials: BB
authors.lastname: Yarlagadda
authors.forename: Josh C
authors.initials: JC
authors.lastname: Meier
authors.forename: Derrick T
authors.initials: DT
authors.lastname: Lin
authors.forename: Kevin S
authors.initials: KS
authors.lastname: Emerick
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Deschler
mesh_terms: D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D059186:Chemoradiotherapy, Adjuvant; D005542:Forearm; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D013524:Surgical Flaps; D014062:Tongue Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*