title: An Assessment of Vitreous Degeneration in Eyes with Vitreomacular Traction and Macular Holes.
abstract: Purpose. To compare the stages of vitreous degeneration in patients with vitreomacular traction (VMT) and macular holes (MH).Methods. A retrospective study was performed analyzing stages of vitreous degeneration of eyes with VMT or MH using swept-source optical coherence tomography (SS-OCT) and spectral-domain optical coherence tomography (SD-OCT). An analogous review was performed on a control group of eyes with contralateral posterior vitreous detachments. Thirty-four eyes with VMT/MH and 39 control eyes were reviewed.Results.Twenty-seven VMT/MH eyes and 31 control eyes were included. Eyes with VMT/MH demonstrated significantly earlier stages of vitreous degeneration when compared to the control group (p= 0.048) despite significantly greater age (p= 0.032).Conclusions. Vitreoretinal interface disease is more often associated with a formed vitreous and an intact premacular bursa. This is contrary to previous assumptions implicating degeneration of vitreous as a precipitating factor of interface disease when in conjunction with abnormal vitreomacular separation.
authors.affiliation: Department of Ophthalmology, Manhattan Eye Ear and Throat Hospital of Northwell Health, 210 East 64th Street, New York, NY 10021, USA; Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022, USA; Department of Ophthalmology, New York University Langone Medical Center, 462 1st Avenue, New York, NY 10016, USA.
authors.forename: Quraish
authors.identifier: 0000-0003-4606-618X
authors.initials: Q
authors.lastname: Ghadiali
authors.affiliation: Department of Ophthalmology, Manhattan Eye Ear and Throat Hospital of Northwell Health, 210 East 64th Street, New York, NY 10021, USA; Department of Ophthalmology, New York University Langone Medical Center, 462 1st Avenue, New York, NY 10016, USA.
authors.forename: Sarwar
authors.initials: S
authors.lastname: Zahid
authors.affiliation: Department of Ophthalmology, Manhattan Eye Ear and Throat Hospital of Northwell Health, 210 East 64th Street, New York, NY 10021, USA; Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022, USA.
authors.forename: Rosa
authors.identifier: 0000-0002-2963-2541
authors.initials: R
authors.lastname: Dolz-Marco
authors.affiliation: Department of Ophthalmology, Manhattan Eye Ear and Throat Hospital of Northwell Health, 210 East 64th Street, New York, NY 10021, USA; Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022, USA; Singapore National Eye Center and Singapore Eye Research Institute, The Academia, 20 College Road, Discovery Tower Level 6, Singapore 169856.
authors.forename: Anna
authors.initials: A
authors.lastname: Tan
authors.affiliation: Department of Ophthalmology, Manhattan Eye Ear and Throat Hospital of Northwell Health, 210 East 64th Street, New York, NY 10021, USA; Vitreous Retina Macula Consultants of New York, 460 Park Avenue, New York, NY 10022, USA; Department of Ophthalmology, New York University Langone Medical Center, 462 1st Avenue, New York, NY 10016, USA.
authors.forename: Michael
authors.identifier: 0000-0001-7582-2672
authors.initials: M
authors.lastname: Engelbert