title: Comparison of Hemodynamic Performance and Clinical Results with EVAHEART Versus HeartMate II.
abstract: This study aimed to compare the hemodynamic performance and clinical results of the EVAHEART and HeartMate II left ventricular assist devices (LVADs). From 2007 to 2016, fourteen patients received EVAHEART and 28 received HeartMate II at our center. Early survival, driveline infection, and neurologic events were evaluated. Hemodynamic performance was evaluated with transthoracic echocardiography and right heart catheterization. Mean follow-up was 35.5 ± 14.8 months for EVAHEART and 29.8 ± 6.5 months for HeartMate II. Survival rates were comparable between the two groups. After 24 months, freedom from driveline infection was 28% with EVAHEART, and 85% with HeartMate II; freedom from neurologic events was 21% with EVAHEART, and 89% with HeartMate II. Serum lactate dehydrogenase was significantly lower with EVAHEART. There was a significantly greater decrease in left ventricular size with HeartMate II. In catheter examination performed 1 month postoperatively, HeartMate II recipients had significantly lower pulmonary capillary wedge pressure and mean pulmonary pressure, despite a comparable cardiac index. Both devices provided excellent clinical results and hemodynamic performance. HeartMate II could be a better choice to avoid driveline infection and neurologic events. Our results suggest that HeartMate II reduced right ventricular afterload. However, further analysis of more cases is required.
authors.affiliation: From the Departments of *Cardiovascular Surgery; ‡Transplantation, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan; and †Department of Cardiovascular Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Yorihiko
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Fujita
authors.forename: Satsuki
authors.initials: S
authors.lastname: Fukushima
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hata
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Shimahara
authors.forename: Yuta
authors.initials: Y
authors.lastname: Kume
authors.forename: Kizuku
authors.initials: K
authors.lastname: Yamashita
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kuroda
authors.forename: Seiko
authors.initials: S
authors.lastname: Nakajima
authors.forename: Takuma
authors.initials: T
authors.lastname: Sato
authors.forename: Osamu
authors.initials: O
authors.lastname: Seguchi
authors.forename: Masanobu
authors.initials: M
authors.lastname: Yanase
authors.forename: Norihide
authors.initials: N
authors.lastname: Fukushima
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Shimizu
authors.forename: Junjiro
authors.initials: J
authors.lastname: Kobayashi
mesh_terms: D000328:Adult; D005260:Female; D006333:Heart Failure / Q000401:mortality / Q000628:therapy; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015996:Survival Rate