title: Multivalency in Rab effector interactions.
abstract: Rab proteins regulate vesicular transport in eukaryotic cells and establish connections to various cellular structures and processes by interacting with so-called effector molecules. Several of these effectors are known to not only bind a single Rab protein, but to be able to bind multiple different Rabs simultaneously. In this review we will give a short overview of effectors in general and (putative) functions of the aforementioned multivalent Rab:effector interactions.
authors.affiliation: a Department of Structural Biochemistry , Max Planck Institute of Molecular Physiology , Dortmund , Germany.
authors.forename: Amrita
authors.initials: A
authors.lastname: Rai
authors.affiliation: a Department of Structural Biochemistry , Max Planck Institute of Molecular Physiology , Dortmund , Germany.
authors.forename: Roger S
authors.identifier: 0000-0002-0772-0444
authors.initials: RS
authors.lastname: Goody
authors.affiliation: a Department of Structural Biochemistry , Max Planck Institute of Molecular Physiology , Dortmund , Germany.
authors.forename: Matthias P
authors.identifier: 0000-0002-1529-8933
authors.initials: MP
authors.lastname: Müller
mesh_terms: D011487:Protein Conformation; D020691:rab GTP-Binding Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D020691:rab GTP-Binding Proteins
keywords: EHBPs; Gcc185; Micals; MyoV; Rab effectors; Rabenosyn-5; bMERB; multivalency