title: Consolidative thoracic radiotherapy for extensive stage small cell lung cancer.
abstract: Extensive stage small cell lung cancer (ES-SCLC) represents approximately half of all diagnosed small cell lung cancer worldwide. It is notorious for a high risk of local recurrence although it's sensitive to chemotherapy. Nearly 90% of intrathoracic failures happen in the first year after diagnosis. The cornerstone of treatment for ES-SCLC is etoposide-platinum based chemotherapy. Consolidative radiotherapy to thorax has diminished the incidence of local relapse, therefore it should be offered to patients with excellent response to induction first-line chemotherapy. This review centers on the clinical evidence for the use of thoracic radiotherapy (TRT) and current modalities of TRT delivery, then tries to determine a feasible way to conduct TRT in a selective group of cases.
authors.affiliation: . Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, China.|. Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Zhang
authors.affiliation: . Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, China.|. Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.|. Shandong Academy of Medical Sciences, Jinan University, Jinan, China.
authors.forename: Jinming
authors.initials: J
authors.lastname: Yu
authors.affiliation: . Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.|. Shandong Academy of Medical Sciences, Jinan University, Jinan, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhu
authors.affiliation: . Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.|. Shandong Academy of Medical Sciences, Jinan University, Jinan, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Meng
authors.affiliation: . Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.|. Shandong Academy of Medical Sciences, Jinan University, Jinan, China.
authors.forename: Minghuan
authors.initials: M
authors.lastname: Li
authors.affiliation: . Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.|. Shandong Academy of Medical Sciences, Jinan University, Jinan, China.
authors.forename: Liyang
authors.initials: L
authors.lastname: Jiang
authors.affiliation: . Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.|. Weifang Medical University, Weifang, China.
authors.forename: Xingchen
authors.initials: X
authors.lastname: Ding
authors.affiliation: . Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Science, Jinan, China.|. Shandong Academy of Medical Sciences, Jinan University, Jinan, China.
authors.forename: Xindong
authors.initials: X
authors.lastname: Sun
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D055752:Small Cell Lung Carcinoma / Q000473:pathology / Q000532:radiotherapy*; D013899:Thoracic Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D016896:Treatment Outcome
keywords: extensive stage; small cell lung cancer; thoracic radiotherapy