title: 1-Butyl-3-Methylimidazolium Tetrafluoroborate Film as a Highly Selective Sensing Material for Non-Invasive Detection of Acetone Using a Quartz Crystal Microbalance.
abstract: Breath acetone serves as a biomarker for diabetes. This article reports 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF₄]), a type of room temperature ionic liquid (RTIL), as a selective sensing material for acetone. The RTIL sensing layer was coated on a quartz crystal microbalance (QCM) for detection. The sensing mechanism is based on a decrease in viscosity and density of the [bmim][BF₄] film due to the solubilization of acetone leading to a positive frequency shift in the QCM. Acetone was detected with a linear range from 7.05 to 750 ppmv. Sensitivity and limit of detection were found to be 3.49 Hz/ppmv and 5.0 ppmv, respectively. The [bmim][BF₄]-modified QCM sensor demonstrated anti-interference ability to commonly found volatile organic compounds in breath, e.g., isoprene, 1,2-pentadiene,d-limonene, anddl-limonene. This technology is useful for applications in non-invasive early diabetic diagnosis.
authors.affiliation: Shenzhen Key Laboratory of Special Functional Materials & Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China. wenyan_tao@hotmail.com.|Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China. wenyan_tao@hotmail.com.
authors.forename: Wenyan
authors.initials: W
authors.lastname: Tao
authors.affiliation: Shenzhen Key Laboratory of Special Functional Materials & Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China. lin.peng@szu.edu.cn.
authors.forename: Peng
authors.initials: P
authors.lastname: Lin
authors.affiliation: Department of Biomedical Engineering, the Chinese University of Hong Kong, Shatin, Hong Kong 999077, China. sililiu2007@gmail.com.
authors.forename: Sili
authors.initials: S
authors.lastname: Liu
authors.affiliation: College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410082, China. xieqj@hunnu.edu.cn.
authors.forename: Qingji
authors.initials: Q
authors.lastname: Xie
authors.affiliation: Shenzhen Key Laboratory of Special Functional Materials & Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China. smke@szu.edu.cn.
authors.forename: Shanming
authors.initials: S
authors.lastname: Ke
authors.affiliation: Shenzhen Key Laboratory of Special Functional Materials & Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China. zengxier@szu.edu.cn.|Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China. zengxier@szu.edu.cn.
authors.forename: Xierong
authors.initials: X
authors.lastname: Zeng
mesh_terms: D000096:Acetone; D053138:Cyclohexenes; D007093:Imidazoles; D000077222:Limonene; D011791:Quartz; D058525:Quartz Crystal Microbalance Techniques; D013729:Terpenes
chemical_list: C419324:1-butyl-3-methylimidazolium tetrafluoroborate; D053138:Cyclohexenes; D007093:Imidazoles; D013729:Terpenes; D000096:Acetone; D011791:Quartz; D000077222:Limonene
keywords: 1-butyl-3-methylimidazolium tetrafluoroborate; acetone; non-invasive sensing; quartz crystal microbalance