title: Reply.
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain.
authors.forename: Jose
authors.initials: J
authors.lastname: Pinto-Fraga
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: López-Miguel
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain.
authors.forename: María J
authors.initials: MJ
authors.lastname: González-García
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain.
authors.forename: Itziar
authors.initials: I
authors.lastname: Fernández
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: López-de-la-Rosa
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain.
authors.forename: Amalia
authors.initials: A
authors.lastname: Enríquez-de-Salamanca
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Stern
authors.affiliation: IOBA, University of Valladolid, Valladolid, Spain. Electronic address: calonge@ioba.med.uva.es.
authors.forename: Margarita
authors.initials: M
authors.lastname: Calonge