title: Congenital mesoblastic nephroma 50 years after its recognition: A narrative review.
abstract: Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.
authors.affiliation: Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.|Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
authors.forename: S L
authors.initials: SL
authors.lastname: Gooskens
authors.affiliation: Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.|Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
authors.forename: M E
authors.initials: ME
authors.lastname: Houwing
authors.affiliation: Department of Cellular Pathology, University Hospital of Wales/Cardiff, University School of Medicine, Heath Park, Cardiff, United Kingdom.
authors.forename: G M
authors.initials: GM
authors.lastname: Vujanic
authors.affiliation: Division of Oncology, Children's National Health System, Washington, District of Columbia.
authors.forename: J S
authors.initials: JS
authors.lastname: Dome
authors.affiliation: Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
authors.forename: T
authors.initials: T
authors.lastname: Diertens
authors.affiliation: Department of Pathology, Hopitaux Universitaires Est Parisien, Trousseau La Roche-Guyon, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Coulomb-l'Herminé
authors.affiliation: Department of Emergency Medicine, Medical University of Wroclaw, Wroclaw, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Godzinski
authors.affiliation: Cancer Section, University College London Institute of Child Health, London, United Kingdom.
authors.forename: K
authors.initials: K
authors.lastname: Pritchard-Jones
authors.affiliation: Department of Pediatric Hematology and Oncology, Saarland University, Saarbrucken, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Graf
authors.affiliation: Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
authors.forename: M M
authors.initials: MM
authors.lastname: van den Heuvel-Eibrink
mesh_terms: D006801:Humans; D007680:Kidney Neoplasms; D018201:Nephroma, Mesoblastic
keywords: clinical characteristics; congenital mesoblastic nephroma; genetics; histology; infancy; outcome; renal tumor; review; treatment