title: GRAM-NEGATIVE BACTERIA FROM PATIENTS WITH ENDOPHTHALMITIS: DISTRIBUTION OF ISOLATES AND ANTIMICROBIAL SUSCEPTIBILITIES.
abstract: OBJECTIVE
  To study the distribution of isolates and antimicrobial susceptibility of gram-negative bacteria among culture-positive vitreous samples from patients with endophthalmitis.
  
  
  METHODS
  The records from culture-positive vitreous isolates (endophthalmitis cases) during a 24-year period (December 1990 to December 2014), at the Microbiology Department of Bascom Palmer Eye Institute were reviewed.
  
  
  RESULTS
  In the current study, gram-negative bacteria were reported in 246 (11.5%) of 2,134 vitreous isolates from endophthalmitis patients during 24-year period (December 1990 to December 2014) from a University Referral Center. The antimicrobial susceptibility to fluoroquinolones, aminoglycosides, carbapenems, and ceftazidime remained stable among gram-negative bacteria during the study period.
  
  
  CONCLUSIONS
  Antibiotic susceptibility pattern of gram-negative bacteria from vitreous isolates did not change significantly during the 24-year study period.
authors.affiliation: Departments of Microbiology, and.
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Wilson
authors.affiliation: Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Relhan
authors.affiliation: Departments of Microbiology, and.
authors.forename: Darlene
authors.initials: D
authors.lastname: Miller
authors.affiliation: Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida.
authors.forename: Harry W
authors.initials: HW
authors.lastname: Flynn
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004198:Disease Susceptibility; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005500:Follow-Up Studies; D005544:Forecasting; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D012189:Retrospective Studies; D014822:Vitreous Body / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents