title: Associations of maternal pre-pregnancy body mass index and gestational weight gain with birth outcomes in Shanghai, China.
abstract: Recent data suggests that abnormal maternal pre-pregnancy body mass index (BMI) or gestational weight gain (GWG) is associated with unfavorable delivery outcomes. However, limited clinical evidence is available to support this correlation in China. Participating 510 mother-infant pairs were recruited from the Shanghai First Maternity and Infant Hospital, China, between January 1stand 30th2016. Maternal pre-pregnancy BMI was categorized according to the China's classification and GWG according to the 2009 Institute of Medicine recommendations (IOM). Linear regression tested the associations between pre-pregnancy BMI or GWG and length of gestation, birthweight, length, and head circumference. Logistic regression assessed the associations between pre-pregnancy BMI or GWG and macrosomic, small- (SGA) and large- (LGA) for-gestational-age infants. Overweight/obese women showed increased length of gestation and birthweight, but did not have a higher risk of macrosomic and LGA infants compared with normal weight women. Women with excessive GWG showed increased length of gestation, birthweight, length, and head circumference, and were more likely to deliver macrosomic and LGA infants compared with women with adequate GWG. Although a relatively low proportion of women from Shanghai area are overweight/obese or exhibit excessive GWG, both high pre-pregnancy BMI and excessive GWG influence perinatal outcomes.
authors.affiliation: Department of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
authors.forename: Lingli
authors.initials: L
authors.lastname: Xiao
authors.affiliation: Department of Pediatrics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
authors.forename: Guodong
authors.initials: G
authors.lastname: Ding
authors.affiliation: Department of Obstetrics &Gynaecology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Headley Way, Oxford, OX3 9DU, UK.
authors.forename: Angela
authors.initials: A
authors.lastname: Vinturache
authors.affiliation: Department of Pediatrics, Punan Hospital of Pudong New District, Shanghai 200125, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
authors.forename: Yifang
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Department of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
authors.forename: Jialin
authors.initials: J
authors.lastname: Guo
authors.affiliation: Department of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Huang
authors.affiliation: Department of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
authors.forename: Xuelei
authors.initials: X
authors.lastname: Yin
authors.affiliation: Department of Pediatrics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Qiao
authors.affiliation: Bachelor of medicine and bachelor of surgery (MBBS) 2012, Tongji University School of Medicine, Shanghai 200092, China.
authors.forename: Inesh
authors.initials: I
authors.lastname: Thureraja
authors.affiliation: Department of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Ben
mesh_terms: D000886:Anthropometry; D001724:Birth Weight; D001824:Body Constitution; D015992:Body Mass Index; D002681:China; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome; D015430:Weight Gain