title: Central Systolic Hypertension in Patients with Well-Controlled Hypertension.
abstract: Background. Central systolic blood pressure (CSBP) has prognostic significance and simplified devices for its estimation have been introduced recently. The aim of this study was to assess the achievement of the target CSBP in treated hypertensive patients.Subjects and Methods. One hundred patients with well-controlled hypertension were analysed. For CSBP estimation, we used the Arteriograph (TensioMed Ltd.), which uses one cuff for all measurements, the "single-point measurement" approach.Results. We found that 62% of patients had CSBP ≥ 130 mmHg, the suggested cut-off value for hypertension. When sex-specific classification was employed (CSBP ≥ 137 mmHg for female and CSBP ≥ 133 mmHg for male), only 13% of patients (mainly women) remained in the hypertensive range. We also found that 55% of patients had a CSBP higher than brachial pressure. Multiple analyses showed that CSBP was significantly associated with sex, height, and return time.Conclusions. A high proportion of treated hypertensive patients had CSBP levels that exceeded their brachial BP. CSBP positively correlated with lower height and shorter return time of the reflected pressure wave and was significantly higher in females compared to males. These findings suggest that, for CSBP classification, it is important to take height and sex-specific differences into account.
authors.affiliation: 1st Department of Internal Medicine, Comenius University, Faculty of Medicine, Mickiewiczova 13, 813 69 Bratislava, Slovakia.
authors.forename: Jozef
authors.identifier: 0000-0002-4457-8977
authors.initials: J
authors.lastname: Bulas
authors.affiliation: 1st Department of Internal Medicine, Comenius University, Faculty of Medicine, Mickiewiczova 13, 813 69 Bratislava, Slovakia.
authors.forename: Mária
authors.initials: M
authors.lastname: Potočárová
authors.affiliation: 1st Department of Internal Medicine, Comenius University, Faculty of Medicine, Mickiewiczova 13, 813 69 Bratislava, Slovakia.
authors.forename: Ján
authors.initials: J
authors.lastname: Murín
authors.affiliation: Institute of Medical Physics, Biophysics, Informatics and Telemedicine, Comenius University, Faculty of Medicine, Sasinkova 2, 813 72 Bratislava, Slovakia.
authors.forename: Katarína
authors.initials: K
authors.lastname: Kozlíková
authors.affiliation: Institute of Medical Biology, Genetics and Clinical Genetics, Comenius University, Faculty of Medicine, Sasinkova 4, 813 72 Bratislava, Slovakia.
authors.forename: Ján
authors.initials: J
authors.lastname: Luha
authors.affiliation: 1st Department of Internal Medicine, Comenius University, Faculty of Medicine, Mickiewiczova 13, 813 69 Bratislava, Slovakia.
authors.forename: Martin
authors.initials: M
authors.lastname: Čaprnda
mesh_terms: D000368:Aged; D001794:Blood Pressure; D001795:Blood Pressure Determination; D001916:Brachial Artery; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis; D012307:Risk Factors; D012727:Sex Characteristics; D013599:Systole / Q000502:physiology*; D059289:Vascular Stiffness