title: Testing an explanatory model of nurses' intention to report adverse drug reactions in hospital settings.
abstract: OBJECTIVE
  To test an explanatory model of nurses' intention to report adverse drug reactions in hospital settings, based on the theory of planned behaviour.
  
  
  BACKGROUND
  Under-reporting of adverse drug reactions is an important problem among nurses.
  
  
  METHODS
  A cross-sectional design was used. Data were collected with the adverse drug reporting nurses' questionnaire. Confirmatory factor analysis was performed to test the factor validity of the adverse drug reporting nurses' questionnaire, and structural equation modelling was used to test the explanatory model.
  
  
  RESULTS
  The convenience sample comprised 500 Italian hospital nurses (mean age = 43.52). Confirmatory factor analysis supported the factor validity of the adverse drug reporting nurses' questionnaire. The structural equation modelling showed a good fit with the data. Nurses' intention to report adverse drug reactions was significantly predicted by attitudes, subjective norms and perceived behavioural control (R² = 0.16).
  
  
  CONCLUSIONS
  The theory of planned behaviour effectively explained the mechanisms behind nurses' intention to report adverse drug reactions, showing how several factors come into play.
  
  
  CONCLUSIONS
  In a scenario of organisational empowerment towards adverse drug reaction reporting, the major predictors of the intention to report are support for the decision to report adverse drug reactions from other health care practitioners, perceptions about the value of adverse drug reaction reporting and nurses' favourable self-assessment of their adverse drug reaction reporting skills.
authors.affiliation: Department of Nursing, Local Health Authority Roma 4, Civitavecchia, Rome, Italy.
authors.forename: Alessia De
authors.initials: A
authors.lastname: Angelis
authors.affiliation: Department of Psychology, University of Milan-Bicocca, Milan, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Pancani
authors.affiliation: Department of Psychology, University of Milan-Bicocca, Milan, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Steca
authors.affiliation: Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
authors.forename: Sofia
authors.initials: S
authors.lastname: Colaceci
authors.affiliation: National Center of Epidemiology, Surveillance and Health Promotion National Institute of Health, Rome, Italy.
authors.forename: Angela
authors.initials: A
authors.lastname: Giusti
authors.affiliation: Department of Nursing, Local Health Authority Roma 4, Civitavecchia, Rome, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Tibaldi
authors.affiliation: Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
authors.forename: Rosaria
authors.initials: R
authors.lastname: Alvaro
authors.affiliation: Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.
authors.forename: Davide
authors.initials: D
authors.lastname: Ausili
authors.affiliation: Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
authors.forename: Ercole
authors.initials: E
authors.lastname: Vellone
mesh_terms: D000328:Adult; D001291:Attitude of Health Personnel; D064420:Drug-Related Side Effects and Adverse Reactions / Q000523:psychology*; D005260:Female; D006761:Hospitals; D006801:Humans; D033182:Intention; D007588:Job Satisfaction; D008297:Male; D008875:Middle Aged; D009726:Nurses / Q000523:psychology* / Q000592:standards; D015279:Organizational Culture; D012308:Risk Management / Q000941:ethics*; D012647:Self-Assessment; D011795:Surveys and Questionnaires; D000078329:Workforce; D017132:Workplace / Q000523:psychology / Q000592:standards
keywords: adverse drug reaction reporting; nurses; pharmacovigilance; theory of planned behaviour