title: Rosai-Dorfman Disease: Manifestations Outside of the Head and Neck.
abstract: OBJECTIVE
  Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck.
  
  
  CONCLUSIONS
  The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.
authors.affiliation: 1 Department of Radiology, University of Illinois at Chicago, 1740 W Taylor St, Rm 2483 (MC 931), Chicago, IL 60612.
authors.forename: Winnie A
authors.initials: WA
authors.lastname: Mar
authors.affiliation: 2 Department of Radiology, University of North Carolina, Chapel Hill, NC.
authors.forename: Jonathan H
authors.initials: JH
authors.lastname: Yu
authors.affiliation: 3 Department of Radiology, Mayo Clinic, Scottsdale, AZ.
authors.forename: Martha Gracia
authors.initials: MG
authors.lastname: Knuttinen
authors.affiliation: 4 Department of Radiology, Northwestern Memorial Hospital, Chicago, IL.
authors.forename: Jeanne M
authors.initials: JM
authors.lastname: Horowitz
authors.affiliation: 5 Department of Pathology, University of Illinois at Chicago, Chicago, IL.
authors.forename: Odile
authors.initials: O
authors.lastname: David
authors.affiliation: 1 Department of Radiology, University of Illinois at Chicago, 1740 W Taylor St, Rm 2483 (MC 931), Chicago, IL 60612.
authors.forename: Andrew
authors.initials: A
authors.lastname: Wilbur
authors.affiliation: 3 Department of Radiology, Mayo Clinic, Scottsdale, AZ.
authors.forename: Christine O
authors.initials: CO
authors.lastname: Menias
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging*; D003952:Diagnostic Imaging / Q000379:methods*; D006257:Head / Q000000981:diagnostic imaging; D015618:Histiocytosis, Sinus / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009140:Musculoskeletal Diseases / Q000000981:diagnostic imaging*; D009333:Neck / Q000000981:diagnostic imaging; D010388:Pelvis / Q000000981:diagnostic imaging*; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods; D013896:Thoracic Diseases / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: Rosai-Dorfman disease; abdominal; extranodal; histiocytosis; thoracic