title: A missense mutation makes a mess of Ca2+ sensing.
abstract: A new JGP study shows how a disease-causing mutation in RyR2 dramatically alters channel behavior.
authors.forename: Caitlin
authors.identifier: 0000-0001-9984-047X
authors.initials: C
authors.lastname: Sedwick
mesh_terms: D002118:Calcium; D020013:Calcium Signaling; D003600:Cytosol; D020125:Mutation, Missense; D019837:Ryanodine Receptor Calcium Release Channel / Q000235:genetics*
chemical_list: D019837:Ryanodine Receptor Calcium Release Channel; D002118:Calcium