title: Blue Rubber Bleb Nevus Syndrome: Promising Response To Sirolimus.
abstract: BACKGROUND
  Blue rubber bleb nevus syndrome is a rare disease involving venous malformations.
  
  
  METHODS
  We present a 6-year-old female with the syndrome, and consumptive coagulopathy.
  
  
  RESULTS
  After management with sirolimus, symptoms resolved.
  
  
  CONCLUSIONS
  Sirolimus may be a valuable option for reducing bleeding complications and cosmetic sequelae for the patients with this syndrome.
authors.affiliation: Department of Pediatric Oncology, Hacettepe University, Cancer Institute, 06100 Ankara-Turkey. Correspondence to: Dr Burca Aydin, Department of Pediatric Oncology, Hacettepe University, Cancer Institute, 06100 Ankara-Turkey. burcaaydin@yahoo.com.
authors.forename: Canan
authors.initials: C
authors.lastname: Akyuz
authors.forename: Hilal
authors.initials: H
authors.lastname: Susam-Sen
authors.forename: Burca
authors.initials: B
authors.lastname: Aydin
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D002648:Child; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D006391:Hemangioma; D006801:Humans; D018329:Nevus, Blue / Q000188:drug therapy* / Q000473:pathology*; D020123:Sirolimus / Q000627:therapeutic use*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology*
chemical_list: D000903:Antibiotics, Antineoplastic; D020123:Sirolimus