title: Efficacy of Concomitant Therapy with Fluoride and Chlorhexidine Varnish on Remineralization of Incipient Lesions in Young Children.
abstract: OBJECTIVE
  To assess the effect of combined use of chlorhexidine and fluoride varnish on the remineralization of incipient carious lesions in young children.
  
  
  METHODS
  Twenty caries-active children (80 lesions) were randomly divided into four groups and subjected to initial examination. Caries status was assessed visually and with the aid of DIAGNOdent. Baseline enamel biopsies were obtained. Subjects of groups I and II received fluoride and chlorhexidine varnish respectively. Group III received both fluoride and chlorhexidine varnish alternatively, for a period of 4 weeks. Group IV served as the control. At 3-month follow-up, the incipient lesions were assessed again with DIAGNOdent and enamel biopsy.
  
  
  RESULTS
  Increased calcium, phosphate, and fluoride levels were noticed in groups I, II, III compared to group IV, at the 3-month follow-up (p < 0.001).
  
  
  CONCLUSIONS
  The combined therapy with fluoride and chlorhex-idine varnish may be considered an alternative therapy for early reversal of incipient lesions.
  Naidu S, Tandon S, Nayak R, Ratnanag PV, Prajapati D, Kamath N. Efficacy of Concomitant Therapy with Fluoride and Chlorhexidine Varnish on Remineralization of Incipient Lesions in Young Children. Int J Clin Pediatr Dent 2016;9(4):296-302.
authors.affiliation: Assistant Professor, Department of Pedodontics, SB Patil Dental College and Hospital, Bidar, Karnataka, India.
authors.forename: Sarika
authors.initials: S
authors.lastname: Naidu
authors.affiliation: Professor, Faculty of Dentistry, University Technology MARA, Sungai Buloh Campus, Selangor, Malaysia.
authors.forename: Shobha
authors.initials: S
authors.lastname: Tandon
authors.affiliation: Professor and Head, Department of Pedodontics, Manipal College of Dental Sciences, Manipal, Karnataka, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Nayak
authors.affiliation: Reader, Department of Prosthodontics, SB Patil Dental College and Hospital, Bidar, Karnataka, India.
authors.forename: P Venkat
authors.initials: PV
authors.lastname: Ratnanag
authors.affiliation: Assistant Professor, Department of Pedodontics and Preventive Dentistry, NIMS Dental College, Jaipur, Rajasthan, India.
authors.forename: Deepesh
authors.initials: D
authors.lastname: Prajapati
authors.affiliation: Senior Lecturer, Department of Pedodontics, AB Shetty Memorial Institute of Dental Sciences, Mangaluru, Karnataka, India.
authors.forename: Namitha
authors.initials: N
authors.lastname: Kamath
keywords: Chlorhexidine; Fluoride; Incipient lesions; Varnishes.