title: Cardiac MOLLI T1mapping at 3.0 T: comparison of patient-adaptive dual-source RF and conventional RF transmission.
abstract: To prospectively compare image quality and myocardial T1relaxation times of modified Look-Locker inversion recovery (MOLLI) imaging at 3.0 T (T) acquired with patient-adaptive dual-source (DS) and conventional single-source (SS) radiofrequency (RF) transmission. Pre- and post-contrast MOLLI T1mapping using SS and DS was acquired in 27 patients. Patient wise and segment wise analysis of T1times was performed. The correlation of DS MOLLI measurements with a reference spin echo sequence was analysed in phantom experiments. DS MOLLI imaging reduced T1standard deviation in 14 out of 16 myocardial segments (87.5%). Significant reduction of T1variance could be obtained in 7 segments (43.8%). DS significantly reduced myocardial T1variance in 16 out of 25 patients (64.0%). With conventional RF transmission, dielectric shading artefacts occurred in six patients causing diagnostic uncertainty. No according artefacts were found on DS images. DS image findings were in accordance with conventional T1mapping and late gadolinium enhancement (LGE) imaging. Phantom experiments demonstrated good correlation of myocardial T1time between DS MOLLI and spin echo imaging. Dual-source RF transmission enhances myocardial T1homogeneity in MOLLI imaging at 3.0 T. The reduction of signal inhomogeneities and artefacts due to dielectric shading is likely to enhance diagnostic confidence.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany. michael.rasper@tum.de.
authors.forename: Michael
authors.initials: M
authors.lastname: Rasper
authors.affiliation: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Nadjiri
authors.affiliation: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
authors.forename: Alexandra S
authors.initials: AS
authors.lastname: Sträter
authors.affiliation: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
authors.forename: Marcus
authors.initials: M
authors.lastname: Settles
authors.affiliation: Department of Cardiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
authors.forename: Karl-Ludwig
authors.initials: KL
authors.lastname: Laugwitz
authors.affiliation: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
authors.forename: Ernst J
authors.initials: EJ
authors.lastname: Rummeny
authors.affiliation: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.
authors.forename: Armin M
authors.initials: AM
authors.lastname: Huber
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016477:Artifacts; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D019786:Gadolinium DTPA / Q000008:administration & dosage; D006331:Heart Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D019047:Phantoms, Imaging; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D055815:Young Adult
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA
keywords: 3 T; Cardiac T1 mapping; Dual-source RF transmission; MOLLI; RF shimming