title: Effects of dietary chromium exposure to rockfish, Sebastes schlegelii are ameliorated by ascorbic acid.
abstract: Juvenile rockfish Sebastes schlegelii (mean length 10.8±1.4cm, and mean weight 31.7±3.6g) were exposed for 4 weeks with the different levels of dietary chromium (Cr6+) at 0, 120 and 240mg/L and ascorbic acids (AsA) at 100, 200 and 400mg/L. Significant accumulation occurred in specific tissues and hematological parameters were altered: red blood cell count, hematocrit, and hemoglobin increased; plasma components were altered including calcium, glucose, cholesterol, total protein, glutamic oxalate transaminase, and glutamic pyruvate transaminase. However, magnesium and alkaline phosphatase concentrations were unchanged. Ascorbic acids reduced both chromium uptake into tissues and altered hematological parameters.
authors.affiliation: West Sea Fisheries Research Institute, National Institute of Fisheries Science, Incheon 22383, South Korea.
authors.forename: Jun-Hwan
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Aquatic Life Medicine, Pukyong National University, Busan 48513, South Korea. Electronic address: jckang@pknu.ac.kr.
authors.forename: Ju-Chan
authors.initials: JC
authors.lastname: Kang
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000494:pharmacology*; D001492:Bass / Q000502:physiology*; D002857:Chromium / Q000493:pharmacokinetics / Q000633:toxicity*; D004032:Diet / Q000009:adverse effects*; D004906:Erythrocyte Count; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D000637:Transaminases / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D000975:Antioxidants; D006454:Hemoglobins; D014874:Water Pollutants, Chemical; D002857:Chromium; D000637:Transaminases; D001205:Ascorbic Acid
keywords: Accumulation; Ascorbic acid; Chromium; Hematological parameters; Sebastes schlegelii