title: The Role of Microsatellites in Streptophyta Gene Evolution.
abstract: Microsatellites form hotspot regions for recombination. In this research, we investigated whether genic microsatellites can be responsible for generating new genes by enhancing crossover between gene containing microsatellites and other genomic regions. We tested our hypothesis on 33,531 UniGene entries containing microsatellites. Each sequence was divided into microsatellites upstream and downstream fragments, and each pair of sequences was compared to study the microsatellites effect. The candidate pairs of genes are supposed to share a high similar fragment in one side of the microsatellites, while the other fragments should be completely different. This in silico approach detected 448 valid pairs of sequences in which both of them showed semi-resemblance nature. The synteny analysis for the detected sequences against 55 plant genomes indicated low representation of them across plant kingdom. Our results will add a body of knowledge toward understanding the role of microsatellites in gene evolution.
authors.affiliation: Agriculture Victoria, Bioscience Research, AgriBio, Centre for AgriBiosciences, Bundoora, VIC, 3083, Australia. Abdulqader.jighly@ecodev.vic.gov.au.|School of Applied Systems Biology, La Trobe University, Bundoora, VIC, 3083, Australia. Abdulqader.jighly@ecodev.vic.gov.au.|The International Center for Agricultural Research in the Dry Areas (ICARDA), Cairo, Egypt. Abdulqader.jighly@ecodev.vic.gov.au.
authors.forename: Abdulqader
authors.identifier: 0000-0002-2712-3698
authors.initials: A
authors.lastname: Jighly
authors.affiliation: The International Center for Agricultural Research in the Dry Areas (ICARDA), Cairo, Egypt.|Department of Horticulture and Crop Science, Faculty of Agriculture, The University of Jordan, Amman, 11942, Jordan.
authors.forename: Ayed M
authors.initials: AM
authors.lastname: Al-Abdallat
authors.affiliation: Computer Information Systems Department, The University of Jordan, Amman, Jordan.
authors.forename: Loai M
authors.initials: LM
authors.lastname: Alnemer
mesh_terms: D019143:Evolution, Molecular; D020224:Expressed Sequence Tags; D017343:Genes, Plant / Q000235:genetics; D018745:Genome, Plant / Q000235:genetics; D023281:Genomics / Q000379:methods; D018895:Microsatellite Repeats / Q000235:genetics*; D057949:Streptophyta / Q000235:genetics*; D026801:Synteny / Q000235:genetics
keywords: EST; Gene evolution; Microsatellites