title: Comparative Evaluation of Bioactive Synthetic NovaBone Putty and Calcified Algae-derived Porous Hydroxyapatite Bone Grafts for the Treatment of Intrabony Defects.
abstract: BACKGROUND
  To compare and evaluate clinically and radio-graphically the bone regeneration and the amount of bone fill in intrabony component of periodontal osseous defects through the osteoconductive and osteostimulative effect of bioactive synthetic NovaBone Putty - CMF and osteoconductive effect of calcified algae-derived porous hydroxyapatite Frios®Algi-pore®bone grafts.
  
  
  METHODS
  Twenty-two sites in 11 patients, within the age range of 25 to 60 years, showing intrabony defects were selected according to split mouth design and divided into group I (Frios®Algipore®) and group II (NovaBone Putty - CMF). All the selected sites were assessed with the clinical and radiographic parameters like plaque index, gingival index (full mouth and site specific), sulcus bleeding index, probing pocket depth, clinical attachment level, gingival recession, and radiographic bone fill. All the clinical and radiographic parameter values obtained at different intervals (baseline, 3, and 6 months) were subjected to statistical analysis.
  
  
  RESULTS
  A statistically significant reduction in pocket depth of 2.55 ± 0.52 mm (group I), 2.64 ± 0.67 mm (group II) and gain in clinical attachment level of 7.55 ± 1.44 mm (group I), 7.55 ± 2.38 mm (group II) were recorded at the end of the study. A slight increase in gingival recession was observed. The mean percentage change in amount of radiographic bone fill of group II (71.34%) was more than group I (61.93%).
  
  
  CONCLUSIONS
  Both NovaBone Putty - CMF and Frios®Algipore®improve healing outcomes and lead to a reduction of probing depth, a resolution of osseous defects, and a gain in clinical attachment, but radiographic observation found better results with NovaBone Putty.
  Bembi NN, Bembi S, Mago J, Baweja GK, Baweja PS. Comparative Evaluation of Bioactive Synthetic NovaBone Putty and Calcified Algae-derived Porous Hydroxyapatite Bone Grafts for the Treatment of Intrabony Defects. Int J Clin Pediatr Dent 2016;9(4):285-290.
authors.affiliation: Reader, Department of Periodontia, Shaheed Kartar Singh Sarabha Dental College and Hospital, Ludhiana, Punjab, India.
authors.forename: Nitika N
authors.initials: NN
authors.lastname: Bembi
authors.affiliation: Professor, Department of Endodontia, Shaheed Kartar Singh Sarabha Dental College and Hospital, Ludhiana, Punjab, India.
authors.forename: Sumit
authors.initials: S
authors.lastname: Bembi
authors.affiliation: Senior Lecturer, Department of Oral Medicine and Radiology, Shaheed Kartar Singh Sarabha Dental College and Hospital, Ludhiana, Punjab India.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Mago
authors.affiliation: Reader, Department of Prosthodontics, Guru Nanak Dev Dental College and Hopsital, Patiala, Punjab, India.
authors.forename: Gurpreet Kaur
authors.initials: GK
authors.lastname: Baweja
authors.affiliation: Reader, Department of Endodontia, Shaheed Kartar Singh Sarabha Dental College and Hospital, Ludhiana, Punjab, India.
authors.forename: Parvinder Singh
authors.initials: PS
authors.lastname: Baweja
keywords: Bone grafts; Bone regeneration; Intrabony defects.