title: [Prognostic Prediction Models for Liver Metastasis of Colorectal Cancer].
abstract: We developed a reliable prediction model for colorectal cancer(CRC)patients after surgically curative resection. Using clinicopathological factors, prediction models were constructed for liver metastasis-free survival(LMFS). Between January 2004 and December 2010, 528 CRC patients were investigated. On univariate analysis of clinicopathological factors, the following factors associated with LMFS: pathological tumor invasion, lymph node metastasis, lymphatic invasion, venous invasion, and preoperative serum CEA. Using these factors, a prediction model was constructed using a Cox regression model with a concordance index of 0.824 for LMFS. These individualized prediction models could help clinicians in the treatment of postoperative CRC patients.
authors.affiliation: Dept. of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases.
authors.forename: Ryuichiro
authors.initials: R
authors.lastname: Kimura
authors.forename: Norikatsu
authors.initials: N
authors.lastname: Miyoshi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ohue
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yasui
authors.forename: Yuma
authors.initials: Y
authors.lastname: Wada
authors.forename: Shiki
authors.initials: S
authors.lastname: Fujino
authors.forename: Keijiro
authors.initials: K
authors.lastname: Sugimura
authors.forename: Akira
authors.initials: A
authors.lastname: Tomokuni
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Akita
authors.forename: Shogo
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Hidenori
authors.initials: H
authors.lastname: Takahashi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Omori
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Masahiko
authors.initials: M
authors.lastname: Yano
authors.forename: Masato
authors.initials: M
authors.lastname: Sakon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002272:Carcinoembryonic Antigen / Q000097:blood; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence
chemical_list: D002272:Carcinoembryonic Antigen