title: [Therapeutic Strategies with Multidisciplinary Local Therapy for Postoperative Recurrence of Esophageal Cancer].
abstract: We report our experience with tailored treatment comprising resection or radiotherapy for postoperative recurrence of esophageal cancer in 73 patients(35.4%)who were diagnosed with recurrent esophageal cancer after curative resection. The initial recurrence patterns included 7 patients(3.4%)with local recurrence, 38 patients(18.4%)with lymphatic recurrence, 40 patients(19.4%)with hematologic metastases, and 12 patients(5.8%)with dissemination.Twenty -three patients had solitary lung metastases, and good local control was achieved by surgical resection alone.The success rate of intensity modulated radiation therapy (IMRT) for local control was 64.1%, and IMRT was considered effective and less invasive. The 2-year survival rate after successful treatment for recurrence was 53.5%, vs 5.8% after unsuccessful treatment. Improved prognosis for patients with recurrent esophageal cancer can be expected when adequate local control is achieved according to recurrence pattern by surgical resection or IMRT.
authors.affiliation: Dept. of Gastroenterological Surgery, Kanazawa University.
authors.forename: Koichi
authors.initials: K
authors.lastname: Okamoto
authors.forename: Itasu
authors.initials: I
authors.lastname: Ninomiya
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hirose
authors.forename: Jun
authors.initials: J
authors.lastname: Kinoshita
authors.forename: Keishi
authors.initials: K
authors.lastname: Nakamura
authors.forename: Katsunobu
authors.initials: K
authors.lastname: Oyama
authors.forename: Tomoharu
authors.initials: T
authors.lastname: Miyashita
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Tajima
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takamura
authors.forename: Sachio
authors.initials: S
authors.lastname: Fushida
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Takanaka
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Ohta
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery; D008297:Male; D011184:Postoperative Period; D011379:Prognosis; D012008:Recurrence