title: [Interaction of oral form anticancer drugs with grapefruit juice].
abstract: Oral medication (tablets, capsules, suspensions, liquids, etc.) are frequently used in therapy. This may arise due to the fact that oral medication patient can take at home and it reduce the stress associated with taking the drug. On the Polish pharmaceutical market can be observed more frequent registration to trading anticancer drugs in oral form. Is also growing interest about drug interactions with food, but they are still less accented than drug-drug interactions. The results of pharmacokinetic studies on the interaction of drugs used in antineoplastic therapy with food are particularly important because of the characteristics of cancer patients, and a growing number of people suffering from cancer and which may have a problem. The aim of the study was to collect and present clinically relevant interactions of anticancer drugs in oral form used in oncology with grapefruit juice based on the latest scientific reports and the summary of product characteristics.
authors.affiliation: Medical University of Silesia in Katowice, School of Public Health in Bytom, Poland: Department of Human Nutrition.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Cholewka-Stafińska
authors.affiliation: Medical University of Silesia in Katowice, School of Public Health in Bytom, Poland: Department of Human Nutrition.
authors.forename: Renata
authors.initials: R
authors.lastname: Polaniak
authors.affiliation: Medical University of Silesia in Katowice, School of Public Health in Bytom, Poland: Department of Food Technology and Quality Evaluation.
authors.forename: Marek
authors.initials: M
authors.lastname: Kardas
authors.affiliation: Medical University of Silesia in Katowice, School of Public Health in Bytom, Poland: Department of Food Technology and Quality Evaluation.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Grajek
authors.affiliation: Medical University of Silesia in Katowice, School of Public Health in Bytom, Poland: Department of Human Nutrition.
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Grochowska-Niedworok
mesh_terms: D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D032083:Citrus paradisi; D018565:Food-Drug Interactions; D000067030:Fruit and Vegetable Juices; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents
keywords: drug- food interactions; grapefruit; interactions; oncological medicines