title: [Successful Treatment of Local Recurrence of Advanced Gastric Cancer Using Curative Gastrectomy via Distal Pancreatectomy after Chemoradiotherapy].
abstract: The patient was a 65-year-old woman. She was diagnosed with advanced gastric cancer with liver invasion. After receiving systemic chemotherapy(S-1 plus PTX)for 3 months, she underwent total gastrectomy and partial hepatectomy in May 2008. Because she developed celiac artery circumference lymph node recurrence in November 2010 during postoperative adjuvant chemotherapy consisting of S-1 plus PTX, we changed her chemotherapy regimen to CPT-11 plus CDDP. We observed an increase in the size of the lymph nodes in August 2013 and the response was poor even after switching to DOC. However, the lymph nodes continued to increase in size and we administered radiotherapy of 60.4 Gy/33 Fr that resulted in shrinkage of the nodes. We observed an increase in lymph node size and pancreas invasion in September 2015, including an expansion of the mid pancreatic duct. We performed distal pancreatectomy without identifying the recurrence observed in November 2015 assuming it was an exacerbation. Six months after the surgery, the recurrence was not apparent. We report an example of long-term survival that was achieved for Stage IV gastric cancer. The patient underwent combined modality therapy for 8 years, and local recurrence was controlled via a primary operation.
authors.affiliation: Dept. of Surgery, Minoh City Hospital.
authors.forename: Kenji
authors.initials: K
authors.lastname: Sakai
authors.forename: Teruyuki
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Masaya
authors.initials: M
authors.lastname: Higashiguchi
authors.forename: Takashi
authors.initials: T
authors.lastname: Doi
authors.forename: Taichi
authors.initials: T
authors.lastname: Koyama
authors.forename: Minako
authors.initials: M
authors.lastname: Hoshi
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Masakazu
authors.initials: M
authors.lastname: Murakami
authors.forename: Kimimasa
authors.initials: K
authors.lastname: Ikeda
authors.forename: Eiji
authors.initials: E
authors.lastname: Kurokawa
authors.forename: Itsuko
authors.initials: I
authors.lastname: Nakamichi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D059248:Chemoradiotherapy; D005260:Female; D005743:Gastrectomy; D006801:Humans; D010180:Pancreatectomy; D012008:Recurrence; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D016896:Treatment Outcome