title: Ratiometric SERS imaging and selective biosensing of nitric oxide in live cells based on trisoctahedral gold nanostructures.
abstract: Herein, a ratiometric SERS probe was created for monitoring nitric oxide (NO) by designing a novel molecule, 3,4-diaminobenzene-thiol, and immobilizing this molecule onto trisoctahedral gold nanostructures with superior SERS capability. The established probe possessed good selectivity and biocompatibility, high sensitivity and accuracy, thus enabling imaging and biosensing of NO in live cells.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, P. R. China. ytian@chem.ecnu.edu.cn.
authors.forename: Qiao
authors.initials: Q
authors.lastname: Xu
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.forename: Yang
authors.initials: Y
authors.lastname: Tian
mesh_terms: D000818:Animals; D001555:Benzene Derivatives / Q000737:chemistry; D015374:Biosensing Techniques; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009569:Nitric Oxide / Q000032:analysis*; D016716:PC12 Cells; D010316:Particle Size; D051381:Rats; D013059:Spectrum Analysis, Raman; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013499:Surface Properties
chemical_list: D001555:Benzene Derivatives; D013438:Sulfhydryl Compounds; D009569:Nitric Oxide; D006046:Gold