title: Medicinally active principles analysis of Tephrosia apollinea (Delile) DC. growing in the United Arab Emirates.
abstract: BACKGROUND
  Tephrosia apollinea is a leguminous plant and is native to southwest Asia, Arabia, northwestern India and northeast Africa. In traditional system, it is used for medicinal and coloring purpose. The present study aims to explore the phytochemical, proximate analysis, element contents and antioxidant potential of T. apollinea extract.
  
  
  METHODS
  The phytochemical screening was done with qualitative methods. Proximate analysis and elemental composition were performed from powdered sample. In vitro antioxidant assays such as 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and reducing power-scavenging assays were used for evaluating the antioxidant properties.
  
  
  RESULTS
  Qualitative screening of methanolic extract of T. apollinea showed the presence of alkaloids, phenolics, flavonoids, terpenoids, glycosides and saponins. The methanolic extract of T. apollinea exhibited a significant dose dependent inhibition of DPPH activity, with a 50% inhibition (IC50) at a concentration found to be 29.41 µg/ml, which was compared with standard GAE (IC50= 31.09 μg/ml). The reducing power shows good linear relationship in both standard gallic acid (R2= 0.956) and T. apollinea extract (0.984).
  
  
  CONCLUSIONS
  The results of our study clearly suggested that the methanolic extract of T. apollinea may serve as potential source of natural antioxidant for nutraceutical application.
authors.affiliation: Department of Aridland Agriculture, College of Food and Agriculture, United Arab Emirates University, P.O. Box 15551, Al Ain, United Arab Emirates. abdul.jaleel@uaeu.ac.ae.
authors.forename: Abdul J
authors.initials: AJ
authors.lastname: Cheruth
authors.affiliation: Department of Aridland Agriculture, College of Food and Agriculture, United Arab Emirates University, P.O. Box 15551, Al Ain, United Arab Emirates.
authors.forename: Saif A M
authors.initials: SA
authors.lastname: Al Baloushi
authors.affiliation: Department of Aridland Agriculture, College of Food and Agriculture, United Arab Emirates University, P.O. Box 15551, Al Ain, United Arab Emirates.
authors.forename: Kandhan
authors.initials: K
authors.lastname: Karthishwaran
authors.affiliation: Department of Food Science, College of Food and Agriculture, United Arab Emirates University, 15551, Al Ain, United Arab Emirates.
authors.forename: Sajid
authors.initials: S
authors.lastname: Maqsood
authors.affiliation: Department of Aridland Agriculture, College of Food and Agriculture, United Arab Emirates University, P.O. Box 15551, Al Ain, United Arab Emirates.
authors.forename: Shyam S
authors.initials: SS
authors.lastname: Kurup
authors.affiliation: Terrestrial and Marine Biodiversity Sector, Wildlife Assessment and Conservation, Environment Agency-Abu Dhabi, P.O. Box 45553, Abu Dhabi, United Arab Emirates.
authors.forename: Sabitha
authors.initials: S
authors.lastname: Sakkir
mesh_terms: D001713:Biphenyl Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry; D005707:Gallic Acid / Q000494:pharmacology; D000432:Methanol / Q000737:chemistry; D008903:Minerals / Q000032:analysis; D064209:Phytochemicals / Q000032:analysis*; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis; D031304:Tephrosia / Q000737:chemistry* / Q000254:growth & development*; D014479:United Arab Emirates
chemical_list: D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D008903:Minerals; D064209:Phytochemicals; D010851:Picrates; D010936:Plant Extracts; D005707:Gallic Acid; C004931:1,1-diphenyl-2-picrylhydrazyl; D000432:Methanol
keywords: Antioxidant; Free radical; Phytochemical; Proximate; Tephrosia apollinea