title: Proteomic Analyses of Changes in Synechococcus sp. PCC7942 Following UV-C Stress.
abstract: UV-C's effects on the physiological and biochemical processes of cyanobacteria have been well characterized. However, the molecular mechanisms of cyanobacteria's tolerance to UV-C still need further investigation. This research attempts to decode the variation in protein abundances in cyanobacteria after UV-C stress. Different expression levels of proteins in the cytoplasm of Synechococcus sp. PCC7942 under UV-C stress were investigated using a comparative proteomic approach. In total, 47 UV-C-regulated proteins were identified by MALDI-TOF analysis and classified by Gene Ontology (GO). After studying their pathways, the proteins were mainly enriched in the groups of protein folding, inorganic ion transport and energy production. By focusing on these areas, this study reveals the correlation between UV-C stress-responsive proteins and the physiological changes of Synechococcus sp. PCC7942 under UV-C radiation. These findings may open up new areas for further exploration in the homeostatic mechanisms associated with cyanobacteria responses to UV-C radiation.
authors.affiliation: School of Medicine, Nankai University, Tianjin, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Peng
authors.affiliation: College of Life Science and Technology, Xinjiang University, Urumqi, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.affiliation: School of Medicine, Nankai University, Tianjin, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
mesh_terms: D000222:Adaptation, Physiological; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism / Q000528:radiation effects*; D015536:Down-Regulation; D015180:Electrophoresis, Gel, Two-Dimensional; D063990:Gene Ontology; D006706:Homeostasis; D017136:Ion Transport; D017510:Protein Folding; D040901:Proteomics; D060888:Real-Time Polymerase Chain Reaction; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D046940:Synechococcus / Q000378:metabolism* / Q000502:physiology / Q000528:radiation effects*; D014466:Ultraviolet Rays / Q000009:adverse effects*; D015854:Up-Regulation
chemical_list: D001426:Bacterial Proteins