title: Proton Pump Inhibitor-Induced Remission of Lymphocytic Esophagitis.
abstract: Lymphocytic esophagitis is a chronic condition that has been described in the literature; however, there is little information describing its characteristics and treatment. We present a case of lymphocytic esophagitis that was identified following food impaction. Repeat esophagogastroduodenoscopy (EGD) with biopsy showed a marked decrease in lymphocytic infiltration after a 6-week course of twice-daily high-dose proton pump inhibitor (PPI). After initiation of the high-dose PPI regimen, the patient had no further episodes of dysphagia or food impaction. We propose that treating lymphocytic esophagitis with twice-daily PPI can improve symptoms and show histologic evidence of improvement.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Einstein Medical Center, Philadelphia, PA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Sloan
authors.affiliation: Department of Internal Medicine, Einstein Medical Center, Philadelphia, PA.
authors.forename: Naemat
authors.initials: N
authors.lastname: Sandhu
authors.affiliation: Department of Pathology and Laboratory Medicine, Einstein Medical Center, Philadelphia, PA.
authors.forename: Ronald
authors.initials: R
authors.lastname: Miick
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Einstein Medical Center, Philadelphia, PA.
authors.forename: Yogesh
authors.initials: Y
authors.lastname: Govil