title: [A Case of Successful Multidisciplinary Therapy for Advanced Esophagogastric Junction Cancer with Multiple Lymph Node Metastase].
abstract: A 64-year-old man reporting dysphagia was examined. Upper gastrointestinal endoscopy showed a type 3 cancer at the esophagogastric junction. Enhanced CT scan showed several swollen mediastinal and abdominal lymph nodes. We diagnosed the patient with advanced adenocarcinoma of the esophagogastric junction with multiple lymph node metastases(Siewert type II , cT3N2M1[LYM], Stage IV ). After 5 courses of chemotherapy(S-1 plus cisplatin), a significant reduction was observed in the size of the tumor and lymph nodes. Therefore, we performed conversion surgery. The patient underwent esophagectomy and mediastinal lymph node dissection using a right thoracotomy approach. He has survived without recurrence in the 10 months since this radical surgery.
authors.affiliation: Dept. of Surgery, Kansai Rosai Hospital.
authors.forename: Kohei
authors.initials: K
authors.lastname: Murakami
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Tamura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takeno
authors.forename: Tomo
authors.initials: T
authors.lastname: Ishida
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Kuwahara
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Akiyama
authors.forename: Takuya
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Junichi
authors.initials: J
authors.lastname: Inatome
authors.forename: Atsushi
authors.initials: A
authors.lastname: Naito
authors.forename: Yoshiteru
authors.initials: Y
authors.lastname: Katsura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ohmura
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kagawa
authors.forename: Chiyomi
authors.initials: C
authors.lastname: Egawa
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takeda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kato
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000601:surgery; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004338:Drug Combinations; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D016629:Esophagectomy; D004943:Esophagogastric Junction / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use; D005641:Tegafur / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid