title: First complete genome sequence of parainfluenza virus 5 isolated from lesser panda.
abstract: Parainfluenza virus 5 (PIV5) is widespread in mammals and humans. Up to now, there is little information about PIV5 infection in lesser pandas. In this study, a PIV5 variant (named ZJQ-221) was isolated from a lesser panda with respiratory disease in Guangzhou zoo in Guangdong province, southern China. The full-length genome of ZJQ-221 was found to be 15,246 nucleotides and consisted of seven non-overlapping genes encoding eight proteins (i.e., NP, V, P, M, F, SH, HN and L). Sequence alignment and genetic analysis revealed that ZJQ-221 shared a close relationship with a PIV5 strain of canine-origin (1168-1) from South Korea. The findings of this study confirm the presence of PIV5 in lesser panda and indicate this mammal as a possible natural reservoir. Furthermore they highlight the urgent need to strengthen viral surveillance and control of PIV5 in zoo animals.
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
authors.forename: Jun-Qiong
authors.initials: JQ
authors.lastname: Zhai
authors.affiliation: Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China. zhaishaolun@163.com.
authors.forename: Shao-Lun
authors.identifier: http://orcid.org/0000-0003-3217-2256
authors.initials: SL
authors.lastname: Zhai
authors.affiliation: Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 57007, USA.
authors.forename: Tao
authors.initials: T
authors.lastname: Lin
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
authors.forename: Jian-Kui
authors.initials: JK
authors.lastname: Liu
authors.affiliation: Mengzi Animal Disease Prevention and Control Center, Mengzi, 661100, China.
authors.forename: He-Xing
authors.initials: HX
authors.lastname: Wang
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Li
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
authors.forename: He
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
authors.forename: Shu-Zhan
authors.initials: SZ
authors.lastname: Zou
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
authors.forename: Meng-Fan
authors.initials: MF
authors.lastname: Wu
authors.affiliation: Guangzhou Zoo, Guangzhou, 510070, China. guangzhouchenwu@sina.com.
authors.forename: Wu
authors.initials: W
authors.lastname: Chen
authors.affiliation: Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. 710510116@qq.com.
authors.forename: Man-Lin
authors.initials: ML
authors.lastname: Luo
mesh_terms: D053822:Ailuridae / Q000821:virology*; D000818:Animals; D000836:Animals, Zoo / Q000821:virology; D001483:Base Sequence; D002460:Cell Line; D002522:Chlorocebus aethiops; D004279:DNA, Viral / Q000235:genetics*; D016679:Genome, Viral / Q000235:genetics*; D045402:Parainfluenza Virus 5 / Q000235:genetics* / Q000302:isolation & purification; D019351:Rubulavirus Infections / Q000662:veterinary* / Q000821:virology; D017422:Sequence Analysis, DNA; D014709:Vero Cells
chemical_list: D004279:DNA, Viral