title: Quebrachitol: Global Status and Basic Research.
abstract: Recently, there has been a renewed interest in the natural-products-inspired drugs. Quebrachitol (QCT) is one of naturally occurring optically active cyclitols that has now received considerable attention. Until the last decade, it came to be a starting point for the lead discovery. In this review, we had a discussion on the basic research of QCT, including its source, structure, properties, and the recent advances on its application. The biological activities and QCT-inspired leads that are potentially effective for treating human diseases were also discussed.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
authors.forename: Shuqun
authors.initials: S
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Chang
authors.affiliation: State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China. dxkong@mail.hzau.edu.cn.
authors.forename: De-Xin
authors.initials: DX
authors.lastname: Kong
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. zuozhili@mail.kib.ac.cn.|Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming, 650201, China. zuozhili@mail.kib.ac.cn.
authors.forename: Zhili
authors.initials: Z
authors.lastname: Zuo
keywords: Application; Biological activity; Quebrachitol (QCT); Structure