title: [The Local Control Effect of Surgical Treatment after Neoadjuvant Chemoradiotherapy for Rectal Adenocarcinoma with Inguinal Lymph Node Metastasis].
abstract: No consensus has been reached with regard to the optimal treatment strategy and the prognosis of patients with advanced rectal cancer and inguinal lymph node metastasis. We, therefore, retrospectively analyzed the outcomes of 41 patients with locally advanced rectal cancer who underwent surgery after neoadjuvant chemoradiotherapy(NACRT). Six patients, with clinical inguinal lymph node metastasis determined by pretreatment imaging, underwent inguinal lymph node dissections after NACRT. Five patients survived without a relapse. Only 1 patient, who had been diagnosed with pathological inguinal lymph node metastasis, had a relapse in the right iliac lymph node 6 years after surgery. Surgical treatment after NACRT for rectal adenocarcinoma with inguinal lymph node metastasis contributes to an improvement in outcomes. NACRT plus inguinal lymph node dissection is an effective strategy for patients with inguinal lymph node metastasis from rectal adenocarcinoma.
authors.affiliation: Division of Gastrointestinal Surgery, Kobe University Graduate School of Medicine.
authors.forename: Koji
authors.initials: K
authors.lastname: Ueta
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Yamashita
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Sumi
authors.forename: Kiyonori
authors.initials: K
authors.lastname: Kanemitsu
authors.forename: Masashi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Shingo
authors.initials: S
authors.lastname: Kanaji
authors.forename: Taro
authors.initials: T
authors.lastname: Oshikiri
authors.forename: Tetsu
authors.initials: T
authors.lastname: Nakamura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kakeji
mesh_terms: D000230:Adenocarcinoma / Q000628:therapy*; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D059248:Chemoradiotherapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies