title: Concise Syntheses of Hyrtioreticulins C and D via a C-4 Pictet-Spengler Reaction: Revised Signs of Specific Rotations.
abstract: The first syntheses of hyrtioreticulins C and D via a Pictet-Spengler reaction at the C-4 position of the indole rings are described. The synthesis proceeds in only two steps from commercially available starting materials. In this Communication, the structures of the natural products were confirmed. Furthermore, we revise the signs of the specific rotations of hyrtioreticulins C and D.
authors.affiliation: Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido , Ishikari-tobetsu, Hokkaido 0610293, Japan.
authors.forename: Takumi
authors.identifier: 0000-0003-1729-1097
authors.initials: T
authors.lastname: Abe
authors.affiliation: Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido , Ishikari-tobetsu, Hokkaido 0610293, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Yamada
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism
chemical_list: D001688:Biological Products; D026121:Indole Alkaloids; C000620941:hyrtioreticulin C; C000620942:hyrtioreticulin D