title: Outcomes From a Hearing-Targeted Cytomegalovirus Screening Program.
abstract: OBJECTIVE
  Cytomegalovirus (CMV) is the most common congenital infection and nongenetic cause of congenital sensorineural hearing loss in the United States. Utah was the first state to pass legislation mandating CMV screening for newborns who fail newborn hearing screening (NBHS). The study objective was to present outcomes of hearing-targeted CMV screening and determine factors predicting CMV screening.
  
  
  METHODS
  We used Utah Department of Health HiTrack and Vital Records databases to examine CMV screening from 509 infants who failed NBHS in the 24 months after implementation of the Utah legislation. Multivariate logistic regression analyses were conducted to identify predictors of compliance with CMV screening and diagnostic hearing evaluation.
  
  
  RESULTS
  Sixty-two percent of infants who never passed hearing screening underwent CMV screening. Fourteen of 234 infants tested within 21 days were CMV positive; 6 (42.9%) had hearing loss. Seventy-seven percent of eligible infants completed a diagnostic hearing evaluation within 90 days of birth. Compliance with CMV screening was associated with sociodemographic factors, time since the law was enacted, and NBHS protocol. Infants born after the legislation showed greater odds of achieving timely diagnostic hearing evaluation than infants born before the law.
  
  
  CONCLUSIONS
  Incorporating CMV screening into an established NBHS program is a viable option for the identification of CMV in infants failing NBHS. The addition of CMV testing can help a NBHS program attain timely audiological diagnostics within 90 days, an important early hearing detection and intervention milestone.
authors.affiliation: Departments of Family and Consumer Studies and marissa.diener@fcs.utah.edu.
authors.forename: Marissa L
authors.initials: ML
authors.lastname: Diener
authors.affiliation: Departments of Family and Consumer Studies and.
authors.forename: Cathleen D
authors.initials: CD
authors.lastname: Zick
authors.affiliation: Utah Department of Health, Salt Lake City, Utah.
authors.forename: Stephanie Browning
authors.initials: SB
authors.lastname: McVicar
authors.affiliation: Utah Department of Health, Salt Lake City, Utah.
authors.forename: Jill
authors.initials: J
authors.lastname: Boettger
authors.affiliation: Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Utah, Salt Lake City, Utah; and.
authors.forename: Albert H
authors.initials: AH
authors.lastname: Park
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D016208:Databases, Factual; D042241:Early Diagnosis; D004522:Educational Status; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000151:congenital / Q000175:diagnosis* / Q000821:virology; D006320:Hearing Tests; D006801:Humans; D007231:Infant, Newborn; D008484:Medicaid; D009035:Mothers; D015999:Multivariate Analysis; D015997:Neonatal Screening / Q000331:legislation & jurisprudence*; D035781:Siblings; D015406:Single Parent; D014481:United States; D014589:Utah