title: THE EFFECT OF RADIATION THERAPY FOR BONE METASTASIS IN URINARY ORGAN CANCER.
abstract: (Objective) Bone metastasis symptoms are complications that greatly reduce the quality of life (QOL) of cancer patients. We report a retrospective study on the efficacy of radiation therapy for patients with bone metastasis in urinary organ cancer. (Subjects and methods) Subjects are comprised of 17 patients; total irradiated areas consist of 25 sites. There are 5 patients diagnosed with renal cell carcinoma, 1 patient with bladder cancer and 11 patients with prostatic cancer. All of them have undergone radiation therapy for bone metastasis in urinary organ cancer between April 2007 and March 2014 in the Department of Urology, Kanazawa Medical University. The mean age of the patients was 66.7 years old. We looked at irradiated areas, exposure dose and changes of symptom in all patients. (Results) Irradiated areas are thoracolumbar vertebrae (14 sites), cranial base (2 sites), pubic bone (1 site), ilium bone (2 sites), sacral bone (1 site), rib bone (1 site) and hip joint (1 site). The mean exposure dose of one area is 37.5 Gy (13.5-60). 19 irradiated sites which were previously reported to have sharp pain have gained improvement at 16 sites. These 16 sites have comparatively lesser pain or no pain. 8 cases in acknowledgment of walk difficulty, it was with 7 cases walking alone possibility again. (Conclusion) This study showed that radiation therapy have significant improvement in terms of symptoms and QOL for the patients with bone metastasis in urinary organ cancer.
authors.affiliation: Department of Urology, Kanazawa Medical University.
authors.forename: Ippei
authors.initials: I
authors.lastname: Chikazawa
authors.forename: Shinya
authors.initials: S
authors.lastname: Inoue
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakazawa
authors.forename: Dan
authors.initials: D
authors.lastname: Nakai
authors.forename: Takeo
authors.initials: T
authors.lastname: Ishii
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Tachibana
authors.forename: Koudai
authors.initials: K
authors.lastname: Suga
authors.forename: Nobuyo
authors.initials: N
authors.lastname: Morita
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Tanaka
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Ota
authors.forename: Munetaka
authors.initials: M
authors.lastname: Matoba
authors.forename: Katsuhito
authors.initials: K
authors.lastname: Miyazawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D016896:Treatment Outcome; D014565:Urogenital Neoplasms / Q000473:pathology*