title: Childhood social adversity and risk of depressive symptoms in adolescence in a US national sample.
abstract: Childhood social adversity has been associated with an increased risk of depression and other psychiatric disorders in adolescence and early adulthood. However, the role of timing and accumulation of adversities has not yet been established in longitudinal studies. We examined the association between childhood adversities and adolescent depressive symptoms, and the impact of timing and accumulation of adversity.
  
  
  
  Longitudinal data were obtained from the Child Development Supplement to the Panel Study of Income Dynamics (n=2223), a nationally representative survey of US families that incorporates data from parents and their children. Negative binomial regression analysis was used to estimate effects of childhood social adversity on adolescent depressive symptoms, presented as Incidence Rate Ratios with 95% confidence intervals.
  
  
  
  Children exposed to social adversity reported higher levels of adolescent depressive symptoms captured by two depression scales. Single-parent household and residential instability were particularly associated with depressive symptoms. A positive relationship was found between cumulative adversity and the risk of adolescent depression. The timing of exposure appeared to have little effect on the risk of adolescent depressive symptoms.
  
  
  
  The structure of the data implies that alternative causal pathways cannot be fully discounted. The self- or parent-reported data is subject to recall bias.
  
  
  
  Our findings support the long-term negative impact of childhood adversity on adolescent depressive symptoms, regardless of when in childhood the adversity occurs. Policies and interventions to reduce adolescent depressive symptoms need to consider the social background of the family as an important risk or protective factor.
authors.affiliation: Department of Community Health Sciences, Fielding School of Public Health and California Center for Population Research, University of California Los Angeles, Los Angeles, CA, United States; Department of Public Health Sciences, Division of Social Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: embjor@ucla.edu.
authors.forename: Emma
authors.initials: E
authors.lastname: Björkenstam
authors.affiliation: Department of Community Health Sciences, Fielding School of Public Health and California Center for Population Research, University of California Los Angeles, Los Angeles, CA, United States.
authors.forename: Anne R
authors.initials: AR
authors.lastname: Pebley
authors.affiliation: Department of Public Health Sciences, Division of Social Medicine, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Bo
authors.initials: B
authors.lastname: Burström
authors.affiliation: Department of Public Health Sciences, Division of Public Health Epidemiology, Karolinska Institutet, Stockholm, Sweden; Center for Epidemiology and Community Medicine, Stockholm County Council, Stockholm, Sweden.
authors.forename: Kyriaki
authors.initials: K
authors.lastname: Kosidou
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003863:Depression / Q000209:etiology*; D005191:Family Characteristics; D005260:Female; D006801:Humans; D008016:Life Change Events; D008137:Longitudinal Studies; D008297:Male; D010290:Parents; D000297:Psychology, Adolescent; D012044:Regression Analysis; D012307:Risk Factors; D057566:Self Report
keywords: Adolescence; Childhood adversity; Longitudinal; Social adversity depression; Socioeconomic