title: Catalytic Asymmetric Synthesis of Chiral 2-Vinylindole Scaffolds by Friedel-Crafts Reaction.
abstract: A chiral bis(imidazolidine)pyridine (PyBidine)-Ni(OTf)2complex smoothly catalyzed an asymmetric Friedel-Crafts reaction of 2-vinylindoles with nitroalkenes to give chiral indoles in a highly enantioselective manner while maintaining the 2-vinyl functionality. The chiral 2-vinylindoles offer unique chiral scaffolds for diverse transformations.
authors.affiliation: Molecular Chirality Research Center, and Department of Chemistry, Graduate School of Science, Chiba University , 1-33 Yayoi, Inage, Chiba 263-8522, Japan.
authors.forename: Takayoshi
authors.identifier: 0000-0001-9490-3988
authors.initials: T
authors.lastname: Arai
authors.affiliation: Molecular Chirality Research Center, and Department of Chemistry, Graduate School of Science, Chiba University , 1-33 Yayoi, Inage, Chiba 263-8522, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Tsuchida
authors.affiliation: Molecular Chirality Research Center, and Department of Chemistry, Graduate School of Science, Chiba University , 1-33 Yayoi, Inage, Chiba 263-8522, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Miyazaki
authors.affiliation: Molecular Chirality Research Center, and Department of Chemistry, Graduate School of Science, Chiba University , 1-33 Yayoi, Inage, Chiba 263-8522, Japan.
authors.forename: Atsuko
authors.initials: A
authors.lastname: Awata