title: [Report of a Case of Long-Term Survival with Mulitidisciplinary Therapy for a Patient with Multiple Liver Metastases from Rectal Cancer].
abstract: Multidisciplinary therapy is necessary to prevent recurrence of advanced rectal cancer and advanced cancer with metastases. Here we report a case of long-term survival of a patient with advanced rectal cancer with multiple liver metastases. An 80's woman had previously undergone both Hartmann's operation and a partial hepatectomy for advanced rectal cancer with multiple liver metastases. A year after chemotherapy, a CT scan revealed multiple liver metastases. Thus, we performed partial liver resection. After another round of chemotherapy, a CT scan revealed lung metastases and local recurrence of the rectal cancer; therefore, we performed partial lung resection and a Miles operation. These procedures were conducted 4 years after her first operation. The following year, PET-CT revealed a mediastinum lymph node metastasis; consequently, we performed radiation therapy. New lung metastases and local recurrences of rectal cancer were identified after the radiation therapy; thus, we resumed the therapy, including a molecular targeting drug. Although the patient is in a tumor-bearing state, she is still alive 10 years after her first operation.
authors.affiliation: Dept. of Surgery, Hiroshima City Hiroshima Citizens Hospital.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Nagai
authors.forename: Masao
authors.initials: M
authors.lastname: Harano
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ogawa
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Komatsu
authors.forename: Naoki
authors.initials: N
authors.lastname: Mimura
authors.forename: Daisuke
authors.initials: D
authors.lastname: Satoh
authors.forename: Daisuke
authors.initials: D
authors.lastname: Sumitani
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Choda
authors.forename: Kanyu
authors.initials: K
authors.lastname: Nakano
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Matsukawa
authors.forename: Yasutomo
authors.initials: Y
authors.lastname: Ojima
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Idani
authors.forename: Masazumi
authors.initials: M
authors.lastname: Okajima
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Shiozaki
authors.forename: Tadashi
authors.initials: T
authors.lastname: Onoda
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003082:Colectomy; D003131:Combined Modality Therapy; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D012008:Recurrence