title: [A Case of Port Site Recurrence after Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer].
abstract: It has been suggested that port site recurrence is a potential complication after laparoscopic distal gastrectomy for gastric cancer, especially considering the increased number of laparoscopic surgeries being performed. We encountered a case of an 84-year-old man who was diagnosed with 2 port site recurrences at the navel and right hypochondrium after laparoscopic distal gastrectomy(D2). Pathological diagnosis for the original tumor was tub2, pT4a, pN1(1/38), M0, pStage III A, and HER2(0). As first-line chemotherapy with S-1 plus CDDP for the port site recurrence failed, second-line chemotherapy with ramucirumab plus paclitaxel(RAM plus PTX)was administered. Although RAM plus PTX therapy induced shrinkage of the port site recurrence, liver metastasis was detected as a new lesion. RAM mono-therapy maintained good QOL for 18 months after surgery.
authors.affiliation: Dept. of Organ Regulatory Surgery, Fukushima Medical University.
authors.forename: Shotaro
authors.initials: S
authors.lastname: Fujita
authors.forename: Shinji
authors.initials: S
authors.lastname: Ohki
authors.forename: Koji
authors.initials: K
authors.lastname: Kase
authors.forename: Naoto
authors.initials: N
authors.lastname: Yamauchi
authors.forename: Shun
authors.initials: S
authors.lastname: Chida
authors.forename: Suguru
authors.initials: S
authors.lastname: Hayase
authors.forename: Wataru
authors.initials: W
authors.lastname: Sakamoto
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Monma
authors.forename: Masashi
authors.initials: M
authors.lastname: Takawa
authors.forename: Toru
authors.initials: T
authors.lastname: Ohtake
authors.forename: Koji
authors.initials: K
authors.lastname: Kono
authors.forename: Seiichi
authors.initials: S
authors.lastname: Takenoshita
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D010535:Laparoscopy; D008297:Male; D010094:Oxonic Acid / Q000008:administration & dosage; D012008:Recurrence; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin