title: Silver-mediated radical coupling reaction of isocyanides and alcohols/phenols in the presence of water: unprecedented hydration and radical coupling reaction sequence.
abstract: The radical coupling of isocyanides and alcohols/phenols promoted by silver in the presence of water is reported for the first time, which led to the formation of diverse carbamates. In contrast to the well-known 1,1-addition to form imidoyl radicals, a novel reaction mechanism, involving sequential hydration of isocyanides and coupling with alkoxyl/phenoxyl radicals, is disclosed by combining experimental and theoretical studies.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024, China. bixh507@nenu.edu.cn jpzhang@nenu.edu.cn.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Pin
authors.initials: P
authors.lastname: Xiao
authors.forename: Xiaoxue
authors.initials: X
authors.lastname: Guan
authors.forename: Zhouliang
authors.initials: Z
authors.lastname: Huang
authors.forename: Jingping
authors.initials: J
authors.lastname: Zhang
authors.forename: Xihe
authors.initials: X
authors.lastname: Bi