title: Characteristics of Pregnant Women With Hepatitis B Virus Infection in 5 US Public Health Jurisdictions, 2008-2012.
abstract: We estimated the prevalence of hepatitis B surface antigen (HBsAg), a serologic marker of active hepatitis B virus (HBV) infection, among pregnant women, and estimated the proportion HBsAg-positive pregnant women who had received additional recommended testing.
  
  
  
  From 2008 through 2012, Perinatal Hepatitis B Prevention Programs (PHBPPs) in Florida, Michigan, Minnesota, New York City, and Texas prospectively collected data on demographic characteristics of HBsAg-positive pregnant women. We estimated the prevalence of HBsAg positivity among pregnant women by demographic characteristics using natality data. PHBPPs (excluding Texas) collected additional recommended testing (for hepatitis B e antigen [HBeAg] and/or HBV deoxyribonucleic acid [DNA]) among HBsAg-positive pregnant women to measure levels of viremia.
  
  
  
  During the study period, 15,205 HBsAg-positive women were case-managed. The median age of HBsAg-positive women was 29 years; prenatal HBsAg screening was at a median of 27 weeks pre-delivery. Of 15,205 HBsAg-positive women, 11,293 (74.3%) were foreign-born. In four PHBPPs with 14,098 pregnancies among 12,214 HBsAg-positive women, HBeAg and/or HBV DNA testing was documented for 2,794 (19.8%) pregnancies. The estimated prevalence of HBsAg positivity among pregnant women was 0.38% (17,023 of 4,468,773). HBsAg prevalence was highest among foreign-born women from most regions in Asia (2.0% to 8.7%; with the exception of South Asia, 0.4%) and Africa (3.4%).
  
  
  
  One-fifth of HBsAg-positive pregnant women had documentation for HBeAg and/or HBV DNA, and about one-third reported receiving care for HBV infection during a case-managed pregnancy. Greater emphasis is needed on prenatal evaluation for HBV liver disease care and treatment among pregnant women with HBV infection.
authors.affiliation: Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Division of Viral Hepatitis, Atlanta, GA, USA.
authors.forename: Tanja Y
authors.initials: TY
authors.lastname: Walker
authors.affiliation: Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Division of Viral Hepatitis, Atlanta, GA, USA.
authors.forename: Emily A
authors.initials: EA
authors.lastname: Smith
authors.affiliation: Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Immunization Services Division, Atlanta, GA, USA.
authors.forename: Nancy
authors.initials: N
authors.lastname: Fenlon
authors.affiliation: New York City Department of Health and Mental Hygiene, Bureau of Immunization, Perinatal Hepatitis B Prevention Unit, New York, NY, USA.
authors.forename: Julie E
authors.initials: JE
authors.lastname: Lazaroff
authors.affiliation: Florida Department of Health, Division of Disease Control, Tallahassee, FL, USA.
authors.forename: Cristina
authors.initials: C
authors.lastname: Dusek
authors.affiliation: Michigan Department of Community Health, Division of Immunization, Lansing, MI, USA.
authors.forename: Patrick
authors.initials: P
authors.lastname: Fineis
authors.affiliation: Minnesota Department of Health, Hepatitis Unit, Cross-Cutting Section, Infectious Disease Epidemiology, Prevention and Control, St. Paul, MN, USA.
authors.forename: Susan A
authors.initials: SA
authors.lastname: Crowley
authors.affiliation: Texas Department of State Health Services, ACE Unit, Immunization Branch, Austin, TX, USA.
authors.forename: Ruthie
authors.initials: R
authors.lastname: Benson
authors.affiliation: Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Division of Viral Hepatitis, Atlanta, GA, USA.
authors.forename: Steven L
authors.initials: SL
authors.lastname: Veselsky
authors.affiliation: Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Division of Viral Hepatitis, Atlanta, GA, USA.
authors.forename: Trudy V
authors.initials: TV
authors.lastname: Murphy
mesh_terms: D000293:Adolescent; D000328:Adult; D019090:Case Management / Q000706:statistics & numerical data*; D002648:Child; D054242:Emigrants and Immigrants / Q000706:statistics & numerical data; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology* / Q000208:ethnology; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000453:epidemiology* / Q000208:ethnology; D011295:Prenatal Care / Q000706:statistics & numerical data*; D015995:Prevalence; D011446:Prospective Studies; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens
keywords: hepatitis B; pregnancy; women