title: [A Case of Locally Far-Advanced Colon Cancer Resected by Laparoscopic Surgery after Colonic Stent Insertion and Neoadjuvant Chemotherapy].
abstract: We report a case of locally far-advanced colon cancer resected by laparoscopic surgery after colonic stent insertion and neoadjuvant chemotherapy. A 71-year-old man with obstructive symptoms was admitted to our hospital in July 2015. CT revealed a sigmoid colon tumor infiltrating the retroperitoneum and small intestine. Lower gastrointestinal endoscopy showed a sigmoid colon cancer. Self-expandable metallic stent insertion for obstructive colon cancer alleviated the patient's symptoms quickly. Four courses of neoadjuvant chemotherapy(XELOX)reduced the primary tumor in size, allowing for laparoscopic surgical resection. Combination therapy with colonic stenting and neoadjuvant chemotherapy can be an effective treatment for obstructive colon cancer. However, further studies and additional cases are needed to assess the safety and efficacy of this combination therapy.
authors.affiliation: Dept. of Surgery, Fukuoka Tokushukai Medical Center.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ishii
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Hirano
authors.forename: Taro
authors.initials: T
authors.lastname: Munechika
authors.forename: Keita
authors.initials: K
authors.lastname: Tanaka
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Yonemitsu
authors.forename: Masako
authors.initials: M
authors.lastname: Nomi
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Shibata
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Okamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Maeno
authors.forename: Jun
authors.initials: J
authors.lastname: Yanagisawa
authors.forename: Shunji
authors.initials: S
authors.lastname: Kawamoto
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Noritomi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000069287:Capecitabine; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005472:Fluorouracil / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D045823:Ileus / Q000209:etiology / Q000628:therapy; D010535:Laparoscopy; D008297:Male; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010071:Oxaloacetates; D012811:Sigmoid Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D015607:Stents; D016896:Treatment Outcome
chemical_list: D010071:Oxaloacetates; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil