title: A New Way to Beat Intestinal Pathogens.
abstract: In the gastrointestinal tract, the tug of war for iron may provide a new way to vaccinate. Recent work shows that immunizing mice with siderophores (small molecules that microbes produce to capture iron) foils pathogen colonization and may instead allow a commensal to expand.
authors.affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO, USA. Electronic address: detweile@Colorado.EDU.
authors.forename: Corrella S
authors.initials: CS
authors.lastname: Detweiler
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D000906:Antibodies / Q000276:immunology / Q000494:pharmacology*; D002772:Cholera Toxin / Q000276:immunology; D000069196:Gastrointestinal Microbiome; D041981:Gastrointestinal Tract / Q000382:microbiology; D007114:Immunization; D007501:Iron / Q000378:metabolism*; D051379:Mice; D012475:Salmonella / Q000187:drug effects / Q000378:metabolism*; D012480:Salmonella Infections / Q000517:prevention & control*; D017262:Siderophores / Q000037:antagonists & inhibitors* / Q000276:immunology*
chemical_list: D000276:Adjuvants, Immunologic; D000906:Antibodies; D017262:Siderophores; D002772:Cholera Toxin; D007501:Iron