title: Self-Assembled DNA Tubes Forming Helices of Controlled Diameter and Chirality.
abstract: Multihelical DNA bundles could enhance the functionality of nanomaterials and serve as model architectures to mimic protein filaments on the molecular and cellular level. We report the self-assembly of micrometer-sized helical DNA nanotubes with widely controllable helical diameters ranging from tens of nanometers to a few micrometers. Nanoscale helical shapes of DNA tile tubes (4-, 6-, 8-, 10-, and 12-helix tile tubes) are achieved by introducing discrete amounts of bending and twist through base pair insertions and/or deletions. Microscale helical diameters, which require smaller amounts of twist and bending, are achieved by controlling the intrinsic "supertwist" present in tile tubes with uneven number of helices (11-, 13-, and 15-helix tile tubes). Supertwist fine-tuning also allows us to produce helical nanotubes of defined chirality.
authors.affiliation: Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-Universität (LMU) , Geschwister-Scholl-Platz 1, 80539 München, Germany.
authors.forename: Alexander Mario
authors.initials: AM
authors.lastname: Maier
authors.affiliation: Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-Universität (LMU) , Geschwister-Scholl-Platz 1, 80539 München, Germany.
authors.forename: Wooli
authors.initials: W
authors.lastname: Bae
authors.affiliation: Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-Universität (LMU) , Geschwister-Scholl-Platz 1, 80539 München, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Schiffels
authors.affiliation: Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-Universität (LMU) , Geschwister-Scholl-Platz 1, 80539 München, Germany.
authors.forename: Johannes Friedrich
authors.initials: JF
authors.lastname: Emmerig
authors.affiliation: Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-Universität (LMU) , Geschwister-Scholl-Platz 1, 80539 München, Germany.
authors.forename: Maximilian
authors.initials: M
authors.lastname: Schiff
authors.affiliation: Faculty of Physics and Center for NanoScience, Ludwig-Maximilians-Universität (LMU) , Geschwister-Scholl-Platz 1, 80539 München, Germany.
authors.forename: Tim
authors.identifier: 0000-0002-0040-0173
authors.initials: T
authors.lastname: Liedl
mesh_terms: D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry; D043942:Nanotubes / Q000737:chemistry*; D010316:Particle Size
chemical_list: D004247:DNA
keywords: DNA nanotechnology; DNA self-assembly; chirality; helical nanotubes; protein filament mimics