title: [A Case of Laparoscopic Surgery for Rectal Cancer with Synchronous Lung Metastases after Chemotherapy].
abstract: A woman in her 70's presented with the predominant complaint of bloody stools. She was diagnosed with rectal cancer, and bilateral lymph node and pulmonary metastases were detected on computed tomography(CT). The patient was diagnosed with cT3N3M1a, cStage IV disease. After undergoing a colostomy, the patient was treated with S-1 plus oxaliplatin (SOX), and bevacizumab(Bev). A second CT scan obtained after completion of 7 courses of chemotherapy revealed that the lung metastases had significantly reduced or disappeared. Approximately 7 months after initial treatment, the patient underwent a laparoscopic Hartmann procedure to remove the tumor. The patient is currently under observation while being administered postoperative adjuvant chemotherapy as an outpatient in our department. There is currently no evidence of the safety of laparoscopic-assisted rectal cancer surgery for first-time Stage IV cases. However, when tumor regression has been achieved with chemotherapy, it may be an effective option.
authors.affiliation: Dept. of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yoshida
authors.forename: Hajime
authors.initials: H
authors.lastname: Morohashi
authors.forename: Daichi
authors.initials: D
authors.lastname: Ichinohe
authors.forename: Eri
authors.initials: E
authors.lastname: Yoshida
authors.forename: Kensuke
authors.initials: K
authors.lastname: Okano
authors.forename: Hayato
authors.initials: H
authors.lastname: Nagase
authors.forename: Harue
authors.initials: H
authors.lastname: Akasaka
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Jin
authors.forename: Takuya
authors.initials: T
authors.lastname: Miura
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Sakamoto
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hakamada
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000068258:Bevacizumab / Q000008:administration & dosage; D003125:Colostomy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077150:Oxaliplatin; D010094:Oxonic Acid / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; C079198:S 1 (combination); D005641:Tegafur; D000068258:Bevacizumab; D010094:Oxonic Acid