title: Tb3+-doped LaF3nanocrystals for correlative cathodoluminescence electron microscopy imaging with nanometric resolution in focused ion beam-sectioned biological samples.
abstract: Here, we report the use of rare earth element-doped nanocrystals as probes for correlative cathodoluminescence electron microscopy (CCLEM) bioimaging. This first experimental demonstration shows potential for the simultaneous acquisition of luminescence and electron microscopy images with nanometric resolution in focused ion beam cut biological samples.
authors.affiliation: Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland. inge.herrmann@empa.ch.
authors.forename: K
authors.initials: K
authors.lastname: Keevend
authors.affiliation: Reliability Science and Technology, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Uberlandstrasse 129, 8600 Dubendorf, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Stiefel
authors.affiliation: Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland. inge.herrmann@empa.ch.
authors.forename: A L
authors.initials: AL
authors.lastname: Neuer
authors.affiliation: Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland. inge.herrmann@empa.ch.
authors.forename: M T
authors.initials: MT
authors.lastname: Matter
authors.affiliation: Center for X-ray Analytics, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Uberlandstrasse 129, 8600 Dubendorf, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Neels
authors.affiliation: Department of Medical Physics and Biomedical Engineering, University College London (UCL), Malet Place Engineering Building, London, WC1E 6BT, UK. s.bertazzo@ucl.ac.uk.
authors.forename: S
authors.initials: S
authors.lastname: Bertazzo
authors.affiliation: Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland. inge.herrmann@empa.ch.
authors.forename: I K
authors.identifier: http://orcid.org/0000-0002-3018-6796
authors.initials: IK
authors.lastname: Herrmann
mesh_terms: D000072283:A549 Cells; D005459:Fluorides; D006801:Humans; D007811:Lanthanum; D017348:Microscopy, Electron, Scanning Transmission; D053758:Nanoparticles
chemical_list: C083668:lanthanum trifluoride; D007811:Lanthanum; D005459:Fluorides