title: Features of Malignancy Prevalence among Children in the Aral Sea Region
abstract: Objective: A study of primary cancer morbidity among children and subsequent calculation of average annual
  incidence were carried out for boys and girls, and young men and women in Kazakhstan. Methods: The investigated
  population lived in three areas of the Aral Sea region: designated catastrophe (Aral, Kazalt, Shalkar regions), crisis
  (Zhalagash, Karmakshy, Shiely regions), pre-crisis (Irgiz, Arys, Ulytau regions). Zhanaarka region of Karaganda oblast
  was applied as a control. Parameters were retrospective analyzed for the 10 years from 2004 to 2013. Result: The
  results indicate that indices of children cancer morbidity were slightly higher in the Aral Sea region than in the control
  district, but they were comparable with similar data from studies in other regions. In all areas of the Aral Sea region,
  except for Ulytau, primary cancer morbidity exceeded the control level by 1.3-2.7 times (4.7%000). Hematological
  malignancies, including solid tumors - tumors of musculoskeletal system and skin, digestive system, brain and central
  nervous system predominated. Stress levels in zones of the Aral Sea region were slightly higher in the crisis zone than
  in the catastrophe zone that can be explained by the phenomenon of wave-like dynamics of disease growth risk. Gender
  differences in characteristics of malignancy formation were not more pronounced in the studied region. Conclusion:
  Indices of children cancer are slightly higher in the Aral Sea region than in the control area of Kazakhstan, but they
  are comparable to results for other regions.
authors.affiliation: West Kazakhstan branch of & ldquo; National Centre for Occupational Health and Occupational Diseases& rdquo; MHSD of Kazakhstan. Email: asemaika@mail.ru
authors.forename: Arstan
authors.initials: A
authors.lastname: Mamyrbayev
authors.forename: Nailya
authors.initials: N
authors.lastname: Dyussembayeva
authors.forename: Lyazzat
authors.initials: L
authors.lastname: Ibrayeva
authors.forename: Zhanna
authors.initials: Zh
authors.lastname: Satenova
authors.forename: Anara
authors.initials: A
authors.lastname: Tulyayeva
authors.forename: Nurgul
authors.initials: N
authors.lastname: Kireyeva
authors.forename: Dinara
authors.initials: D
authors.lastname: Zholmukhamedova
authors.forename: Dina
authors.initials: D
authors.lastname: Rybalkina
authors.forename: Galymzhan
authors.initials: G
authors.lastname: Yeleuov
authors.forename: Almasbek
authors.initials: A
authors.lastname: Yeleuov
keywords: Cancer morbidity; Aral sea region; environment; gender differences; children; adolescents