title: Patient evaluation of the redesigned follitropin alfa pen injector.
abstract: We aimed to evaluate the overall impressions of learning and subsequent use of the redesigned GONAL-f® (follitropin alfa) pen injector by women with recent or current infertility requiring assisted reproductive technologies (ART) or in vitro fertilization (IVF).
  
  
  
  This was a simulated-use study including 86 women with infertility and 30 fertility nurses. Nurses trained the women on the use of the redesigned pen. The opinions of the women on the pen injector were collected during a questionnaire interview. Fertility nurse opinions on patient anxiety were collected before training.
  
  
  
  The pen injector was considered easy to learn to use and easy to use, particularly setting the dose and reading the number on the dial. After training, most women felt confident they could self-administer medication without further training. Most women would recommend the redesigned pen injector to friends and family requiring IVF treatment. Overall, fertility nurses overestimated how anxious the women would be when using the pen injector.
  
  
  
  This study demonstrated that both IVF/ART-experienced and -naïve women with infertility found the redesigned pen injector easy to learn to use and to use.
authors.affiliation: a Global Clinical Development , EMD Serono Research and Development Institute , Billerica , MA , USA.
authors.forename: Joan
authors.initials: J
authors.lastname: Schertz
authors.affiliation: b Aequus Research , London , UK.
authors.forename: Hilary
authors.initials: H
authors.lastname: Worton
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D043373:Follicle Stimulating Hormone, Human / Q000008:administration & dosage*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy; D008875:Middle Aged; D009726:Nurses; D011994:Recombinant Proteins / Q000008:administration & dosage; D027724:Reproductive Techniques, Assisted; D012646:Self Administration; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D043373:Follicle Stimulating Hormone, Human; D011994:Recombinant Proteins; C571801:follitropin alfa
keywords: ART; GONAL-f; IVF; follitropin alfa; patients; pen injector