title: Current controversies in radiotherapy for breast cancer.
abstract: Multimodal treatment approaches have substantially improved the outcome of breast cancer patients in the last decades. Radiotherapy is an integral component of multimodal treatment concepts used in curative and palliative intention in numerous clinical situations from precursor lesions such as ductal carcinoma in situ (DCIS) to advanced breast cancer. This review addresses current controversial topics in radiotherapy with special consideration of DCIS, accelerated partial breast irradiation (APBI) and regional nodal irradiation (RNI) and provides an update on the clinical practice guidelines of the Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO).
authors.affiliation: Department of Radiation Oncology, University Hospital Heidelberg and National Center for Radiation Research in Oncology (NCRO), Heidelberg, Germany. david.krug@med.uni-heidelberg.de.
authors.forename: David
authors.initials: D
authors.lastname: Krug
authors.affiliation: University Hospital Schleswig-Holstein, Kiel, Germany.
authors.forename: René
authors.initials: R
authors.lastname: Baumann
authors.affiliation: Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: Wilfried
authors.initials: W
authors.lastname: Budach
authors.affiliation: University Hospital Schleswig-Holstein, Kiel, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Dunst
authors.affiliation: Vivantes Hospital Neukoelln, Berlin, Germany.
authors.forename: Petra
authors.initials: P
authors.lastname: Feyer
authors.affiliation: University Hospital Erlangen, Erlangen, Germany.
authors.forename: Rainer
authors.initials: R
authors.lastname: Fietkau
authors.affiliation: Formerly St.-Vincentius-Hospital, Karlsruhe, Germany.
authors.forename: Wulf
authors.initials: W
authors.lastname: Haase
authors.affiliation: St. Claraspital, Basel, Switzerland.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Harms
authors.affiliation: HELIOS-Hospital Wuppertal, Witten/Herdecke University, Wuppertal, Germany.
authors.forename: Marc D
authors.initials: MD
authors.lastname: Piroth
authors.affiliation: Municipal Hospital, Karlsruhe, Germany.
authors.forename: Marie-Luise
authors.initials: ML
authors.lastname: Sautter-Bihl
authors.affiliation: Paracelsus Medical University Hospital, Salzburg, Austria.
authors.forename: Felix
authors.initials: F
authors.lastname: Sedlmayer
authors.affiliation: Formerly University Hospital Tuebingen, Tuebingen, Germany.
authors.forename: Rainer
authors.initials: R
authors.lastname: Souchon
authors.affiliation: University Hospital Mannheim, Mannheim, Germany.
authors.forename: Frederik
authors.initials: F
authors.lastname: Wenz
authors.affiliation: University Hospital Erlangen, Erlangen, Germany.
authors.forename: Rolf
authors.initials: R
authors.lastname: Sauer
mesh_terms: D001918:Brachytherapy / Q000592:standards*; D001943:Breast Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage
keywords: Accelerated partial breast irradiation; Breast cancer; Ductal carcinoma in situ; Regional nodal irradiation