title: [Potential indications of dalbavancin in clinical practice].
abstract: Dalbavancin is a semisynthetic lipoglycopeptide with two properties that distinguish it from other members of the antibiotic family from which it is derived: a greater intrinsic activity and a very prolonged mean half-life that allows weekly or twice-weekly dosing with a single 1000mg or 1500mg dose, respectively. Because of this half-life, dalbavancin is a unique antibiotic. This drug allows the design of new treatment strategies that facilitate early hospital discharge without the need for vascular access and with guaranteed treatment adherence. Dalbavancin could be used to resolve some of the problems that commonly occur in the management of infections in daily clinical practice, particularly in consolidation therapy in acute processes, infections requiring prolonged treatment and in the prophylaxis of some recurrent processes caused by Gram-positive cocci.
authors.affiliation: Hospital Universitario HM Montepríncipe, Universidad San Pablo CEU, Madrid, España. Electronic address: barberan60@gmail.com.
authors.forename: José
authors.initials: J
authors.lastname: Barberán
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D017334:Teicoplanin / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D017334:Teicoplanin; C469289:dalbavancin
keywords: Dalbavancin; Dalbavancina; Extended half-life; Potential uses; Staphylococcus spp.; Usos potenciales; Vida media prolongada