title: [Alternative Methods of Local Therapy for Complicated Periocular Infections - Two Case Reports].
abstract: BackgroundWounds of the eyelid can usually be cured with common surgical measures and the use of local antibiotics. Here we present two cases to demonstrate that biological debridement and negative pressure vacuum therapy (NPWT), two second line therapies, are effective and possibly superior alternatives to conventional, antibiotic-based approaches.Methodology and ResultA persistent infectious wound of the upper eyelid after surgical debridement of necrotising fasciitis and an upper eyelid abscess with multiple purulent entry points, which was refractory to a five-week antibiotic regimen, were treated with biological debridement and NPWT. The combination of these two therapies leads to an optimal outcome.ConclusionOur cases demonstrate that, in ophthalmology, uncommon methods such as biological debridement and NPWT are quite practicable and are valuable therapeutic options.
authors.affiliation: Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz.
authors.forename: J C
authors.initials: JC
authors.lastname: Giers
authors.affiliation: Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz.
authors.forename: S
authors.initials: S
authors.lastname: Halstenberg
authors.affiliation: Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz.
authors.forename: U
authors.initials: U
authors.lastname: Voßmerbäumer
authors.affiliation: Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz.
authors.forename: S
authors.initials: S
authors.lastname: Pitz
mesh_terms: D000328:Adult; D001762:Blepharitis / Q000175:diagnosis / Q000628:therapy*; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods*; D015817:Eye Infections / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome