title: Synthesis of Phytocannabinoids.
abstract: The changing legal landscape including medicinal and recreational consumption of Cannabis sativa has led to renewed interest to study the chemistry and biology of cannabinoids. The chemistry in this chapter highlights approaches to cannabinoid total synthesis with an emphasis on the implementation of modern methods and tactics, which provide access to modified structures and enable investigations of the biology of the cannabinoid product family.
authors.affiliation: Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, 8093, Zürich, Switzerland. michael.schafroth@org.chem.ethz.ch.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Schafroth
authors.affiliation: Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, 8093, Zürich, Switzerland. carreira@org.chem.ethz.ch.
authors.forename: Erick M
authors.initials: EM
authors.lastname: Carreira
mesh_terms: D002186:Cannabinoids / Q000096:biosynthesis* / Q000737:chemistry; D002188:Cannabis / Q000378:metabolism*; D013237:Stereoisomerism
chemical_list: D002186:Cannabinoids
keywords: Asymmetric; Bisabosqual; Cannabinoids; Conicol; Diastereoselective; Enantioselective; Epiconicol; Machaeriol; Perrottetinene; Stereospecific; Synthesis; Tetrahydrocannabinol; Total synthesis