title: Recent breakthroughs in metabolomics promise to reveal the cryptic chemical traits that mediate plant community composition, character evolution and lineage diversification.
abstract: Contents 952 I. 952 II. 953 III. 955 IV. 956 V. 957 957 References 957 SUMMARY: Much of our understanding of the mechanisms by which biotic interactions shape plant communities has been constrained by the methods available to study the diverse secondary chemistry that defines plant relationships with other organisms. Recent innovations in analytical chemistry and bioinformatics promise to reveal the cryptic chemical traits that mediate plant ecology and evolution by facilitating simultaneous structural comparisons of hundreds of unknown molecules to each other and to libraries of known compounds. Here, I explore the potential for mass spectrometry and nuclear magnetic resonance metabolomics to enable unprecedented tests of seminal, but largely untested hypotheses that propose a fundamental role for plant chemical defenses against herbivores and pathogens in the evolutionary origins and ecological coexistence of plant species diversity.
authors.affiliation: Smithsonian Tropical Research Institute, Apartado 0843-03092, Balboa, Ancón, Republic of Panama.|Center for Biodiversity and Drug Discovery, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, Apartado 0843-01103, Ciudad del Saber, Ancón, Republic of Panama.
authors.forename: Brian E
authors.identifier: http://orcid.org/0000-0002-1723-9822
authors.initials: BE
authors.lastname: Sedio
mesh_terms: D055432:Metabolomics; D010802:Phylogeny; D010944:Plants / Q000737:chemistry* / Q000378:metabolism*; D013045:Species Specificity
keywords: chemical evolution; community ecology; macroevolution; mass spectrometry; nuclear magnetic resonance spectroscopy; species coexistence