title: A comparison of magnetic resonance venography findings and venous occlusion plethysmography variables in postthrombotic syndrome.
abstract: Objective The relation between venous morphology and venous function in postthrombotic syndrome is poorly understood. The aim of this study was to compare obstruction and collateralization as seen with magnetic resonance venography with variables of venous occlusion plethysmography in patients with postthrombotic syndrome. Methods Medical records, magnetic resonance venography and venous occlusion plethysmography data were analyzed in 28 patients (33 legs). Magnetic resonance venography images were scored for degree of obstruction and collateralization in segments of pelvic and abdominal veins and correlated to venous occlusion plethysmography data. Results Obstruction of the inferior vena cava correlated with an overall increase of collaterals ( p < 0.001). The summary scores of collaterals or obstructions did not correlate with venous occlusion plethysmography variables. Relative expelled volume at 4 s correlated inversely with obstruction of the inferior vena cava ( p = 0.045) and vertebral collateralization ( p = 0.033). Conclusions Modest correlations were found between magnetic resonance venography scores and venous occlusion plethysmography variables. Prospective studies with refined scoring and magnetic resonance venography techniques may increase our knowledge further.
authors.affiliation: 1 Department of Vascular Surgery, Karolinska University Hospital, Stockholm, Sweden.|2 Karolinska Instutet, Stockholm, Sweden.
authors.forename: Lena
authors.initials: L
authors.lastname: Blomgren
authors.affiliation: 3 Department of Radiology, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Jan
authors.initials: J
authors.lastname: Engström
authors.affiliation: 2 Karolinska Instutet, Stockholm, Sweden.|4 Department of Clinical Physiology, Södersjukhuset, Stockholm, Sweden.
authors.forename: Stefan
authors.initials: S
authors.lastname: Rosfors
mesh_terms: D000328:Adult; D000368:Aged; D003097:Collateral Circulation; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010690:Phlebography / Q000379:methods*; D010865:Pilot Projects; D010991:Plethysmography; D054070:Postthrombotic Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D012039:Regional Blood Flow; D012189:Retrospective Studies; D012720:Severity of Illness Index; D055815:Young Adult
keywords: Postthrombotic syndrome; chronic venous disease; magnetic resonance venography; proximal venous obstruction; venous collaterals; venous occlusion plethysmography