title: Digenic MEFV/TNFRSF1A autoinflammatory syndrome with relapsing aseptic neutrophilic meningitis and chronic myelitis.
authors.affiliation: Université Paris-Diderot, Assistance Publique Hôpitaux de Paris, Département de Médecine Interne, Hôpital Bichat-Claude Bernard, Paris, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Murarasu
authors.affiliation: Université Paris-Descartes, Assistance Publique Hôpitaux de Paris, Département de Génétique et Biologie Moléculaires, Hôpital Cochin, Paris, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Dodé
authors.affiliation: Unité Médicale des Maladies Auto-Inflammatoires, Hôpital Arnaud de Villeneuve, CHU Montpellier, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Sarrabay
authors.affiliation: Université Paris-Diderot, Assistance Publique Hôpitaux de Paris, Département de Radiologie, Hôpital Bichat-Claude Bernard, Paris, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Klein
authors.affiliation: Université Paris-Diderot, Assistance Publique Hôpitaux de Paris, Département de Médecine Interne, Hôpital Bichat-Claude Bernard, Paris, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Papo
authors.affiliation: Université Paris-Diderot, Assistance Publique Hôpitaux de Paris, Département de Médecine Interne, Hôpital Bichat-Claude Bernard, Paris, France. karim.sacre@aphp.fr.
authors.forename: Karim
authors.initials: K
authors.lastname: Sacré
mesh_terms: D000328:Adult; D000368:Aged; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D002908:Chronic Disease; D004252:DNA Mutational Analysis; D005260:Female; D005334:Fever / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D020022:Genetic Predisposition to Disease; D040941:Heredity; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008582:Meningitis, Aseptic / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D008875:Middle Aged; D009154:Mutation; D009187:Myelitis / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology*; D010375:Pedigree; D010641:Phenotype; D000071198:Pyrin / Q000235:genetics*; D047888:Receptors, Tumor Necrosis Factor, Type I / Q000235:genetics*; D012008:Recurrence; D012074:Remission Induction; D016896:Treatment Outcome
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D007166:Immunosuppressive Agents; C000604192:MEFV protein, human; D000071198:Pyrin; D047888:Receptors, Tumor Necrosis Factor, Type I; C506235:TNFRSF1A protein, human; C502936:tocilizumab