title: Clinical features and management of Plasmodium knowlesi infections in humans.
abstract: Plasmodium knowlesi is a simian malaria of primarily the macaque species of South East Asia. While it was known that human infections could be induced during the years of malariotherapy, naturally occurring P. knowlesi human infections were thought to be rare. However, in 2004, knowlesi infections became recognized as an important infection amongst human populations in Sarawak, Malaysian Borneo. Since then, it has become recognized as a disease affecting people living and visiting endemic areas across South East Asia. Over the last 12 years, clinical studies have improved our understanding of this potentially fatal disease. In this review article the current literature is reviewed to give a comprehensive description of the disease and treatment.
authors.affiliation: Department of Respiratory Medicine,Plymouth Hospitals NHS Trust,Plymouth,UK.
authors.forename: Cyrus
authors.initials: C
authors.lastname: Daneshvar
authors.affiliation: Queen Elizabeth Hospital,Kota Kinabalu,Malaysia.
authors.forename: Timothy
authors.initials: T
authors.lastname: William
authors.affiliation: School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital,Western Australia,Australia.
authors.forename: Timothy M E
authors.initials: TME
authors.lastname: Davis
mesh_terms: D001210:Asia, Southeastern / Q000453:epidemiology; D006801:Humans; D008288:Malaria / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000469:parasitology; D016790:Plasmodium knowlesi / Q000502:physiology*; D015995:Prevalence; D012307:Risk Factors
keywords: 
                 Plasmodium knowlesi
              ; antimalarial; clinical; complicated; malaria; severe; simian; treatment