title: [A Case of Esophageal Submucosal Tumor Undiagnosed Preoperatively and Treated with Thoracoscopic Enucleation].
abstract: An asymptomatic 35-year-old man visited our hospital because of an esophageal abnormality identified on a medical check-up. Gastrointestinal endoscopic examination revealed a 4 cm diameter submucosal tumor(SMT)in the upper esophagus. endoscopic ultrasound fine-needle aspiration biopsy(EUS-FNAB)was performed. Histopathological examination showed that it was strongly positive for a-SMA and partially positive for c-kit. An esophageal leiomyoma was suspected but esophageal gastrointestinal stromal tumor(GIST)could not be completely ruled out. After considering the patient's age and the location of the tumor, we performed thoracic enucleation of the esophageal SMT. Immunostaining findings showed that it was a-SMA positive and S-100 negative. Mast cells, but not tumor cells were partially stained with c-kit. The final pathological diagnosis was leiomyoma. The postoperative course was uneventful. We report this case together with a review of the literature.
authors.affiliation: Dept. of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tokuhisa
authors.forename: Shigeru
authors.initials: S
authors.lastname: Takeda
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Kanekiyo
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Nishiyama
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kitahara
authors.forename: Michihisa
authors.initials: M
authors.lastname: Iida
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Sakamoto
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Suzuki
authors.forename: Tomio
authors.initials: T
authors.lastname: Ueno
authors.forename: Shigeru
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Shigefumi
authors.initials: S
authors.lastname: Yoshino
authors.forename: Shoichi
authors.initials: S
authors.lastname: Hazama
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nagano
mesh_terms: D000328:Adult; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D013906:Thoracoscopy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome