title: Assessing Sensitivity and Specificity of Surveillance Case Definitions for Zika Virus Disease.
abstract: We evaluated performance of 5 case definitions for Zika virus disease surveillance in a human cohort during an outbreak in Singapore, August 26-September 5, 2016. Because laboratory tests are largely inaccessible, use of case definitions that include rash as a required clinical feature are useful in identifying this disease.
authors.forename: Angela
authors.initials: A
authors.lastname: Chow
authors.forename: Hanley
authors.initials: H
authors.lastname: Ho
authors.forename: Mar-Kyaw
authors.initials: MK
authors.lastname: Win
authors.forename: Yee-Sin
authors.initials: YS
authors.lastname: Leo
mesh_terms: D000328:Adult; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012846:Singapore / Q000453:epidemiology; D055815:Young Adult; D000071243:Zika Virus Infection / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology*
keywords: Centers for Disease Control and Prevention; European Centre for Disease Control and Prevention; Pan American Health Organization; Singapore; Singapore Ministry of Health; World Health Organization; Zika virus; Zika virus disease; case definitions; performance; positive likelihood ratio; rash; sensitivity; specificity; surveillance; viruses