title: [The SPRINT study - the outcomes of the most important study over the recent period focused on hypertension].
abstract: When treating systolic hypertension we do not know the optimum blood pressure which leads to the reduction of cardiovascular events and cardiovascular and total mortality. The results of the ACCORD study, when comparing intensive treatment of systolic blood pressure < 120 mm Hg and standard treatment < 140 mm Hg, did not lead to affecting the primary target for patients with diabetes mellitus. In the autumn last year the SPRINT study was presented and published, showing favourable impact on the combined primary target, which involved myocardial infarction, other acute coronary syndromes, stroke, heart failure or death from cardiovascular causes during intensive treatment of systolic blood pressure, i.e. < 120 mm Hg, but on the other hand with a statistically significant incidence of secondary effects (hypotension, syncope, renal impairment or failure).Key words: target values - hypotension - cardiovascular events - systolic blood pressure.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Souček
mesh_terms: D054058:Acute Coronary Syndrome / Q000453:epidemiology; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000401:mortality; D003920:Diabetes Mellitus; D006333:Heart Failure / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007022:Hypotension / Q000139:chemically induced; D015994:Incidence; D009203:Myocardial Infarction / Q000453:epidemiology; D010347:Patient Care Planning; D051437:Renal Insufficiency / Q000139:chemically induced; D020521:Stroke / Q000453:epidemiology; D013575:Syncope / Q000139:chemically induced; D013599:Systole
chemical_list: D000959:Antihypertensive Agents