title: Psychosocial Factors and Comorbidity Associated with Suicide Attempts: Findings in Patients with Bipolar Disorder.
abstract: BACKGROUND
  Suicidal attempts occur more frequently in patients with bipolar disorder compared to other mood disorders. The goal of this study is to identify psychosocial factors and comorbidity associated with this serious and life-threatening behavior.
  
  
  METHODS
  Subjects were 121 patients evaluated and treated at a university outpatient psychiatric clinic. The patients' charts were examined to determine history of suicide attempts, demographic and psychosocial variables, and comorbid symptoms.
  
  
  RESULTS
  Forty-one percent of the subjects had attempted suicide. Patients who were younger at onset of illness (p = 0.02) and those who had been abused (p = 0.003) were more likely to attempt suicide. Suicide attempts were also more common in subjects with a history of alcohol abuse (p = 0.003) and those with psychotic symptoms (p = 0.02).
  
  
  CONCLUSIONS
  Based on the results of this study, it is recommended that increased emphasis be placed on the psychosocial history and comorbid symptoms in patients with bipolar disorder. While asking about previous suicide attempts is the most accurate way to predict suicidal behavior, age of onset, past abuse, and overuse of alcohol may also be helpful. Since suicidal behavior in patients with bipolar disorder is relatively common, intensified efforts to predict this behavior may be life-saving.
authors.affiliation: Department of Psychiatry, The University of Toledo, Toledo, OH, USA.
authors.forename: Angele
authors.initials: A
authors.lastname: McGrady
authors.forename: Denis
authors.initials: D
authors.lastname: Lynch
authors.forename: Daniel
authors.initials: D
authors.lastname: Rapport
mesh_terms: D000328:Adult; D017668:Age of Onset; D000437:Alcoholism / Q000523:psychology; D001714:Bipolar Disorder / Q000453:epidemiology / Q000523:psychology*; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000453:epidemiology / Q000523:psychology*; D012307:Risk Factors; D012720:Severity of Illness Index; D019966:Substance-Related Disorders; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000523:psychology* / Q000706:statistics & numerical data
keywords: Bipolar disorder; Comorbidity; Psychosocial factors; Suicide