title: Comparative analysis of short - term functional outcomes and quality of life in a prospective series of brachytherapy and Da Vinci robotic prostatectomy.
abstract: BACKGROUND
  There is a growing interest in achieving higher survival rates with the lowest morbidity in localized prostate cancer (PC) treatment. Consequently, minimally invasive techniques such as low-dose rate brachytherapy (BT) and robotic-assisted prostatectomy (RALP) have been developed and improved. Comparative analysis of functional outcomes and quality of life in a prospective series of 51BT and 42Da Vinci prostatectomies DV Materials and Methods: Comparative analysis of functional outcomes and quality of life in a prospective series of 93 patients with low-risk localized PC diagnosed in 2011. 51patients underwent low-dose rate BT and the other 42 patients RALP. IIEF to assess erectile function, ICIQ to evaluate continence and SF36 test to quality of life wee employed.
  
  
  RESULTS
  ICIQ at the first revision shows significant differences which favour the BT group, 79% present with continence or mild incontinence, whereas in the DV group 45% show these positive results. Differences disappear after 6 months, with 45 patients (89%) presenting with continence or mild incontinence in the BT group vs. 30 (71%) in the DV group. 65% of patients are potent in the first revision following BT and 39% following DV. Such differences are not significant and cannot be observed after 6 months. No significant differences were found in the comparative analysis of quality of life.
  
  
  CONCLUSIONS
  ICIQ after surgery shows significant differences in favour of BT, which disappear after 6 months. Both procedures have a serious impact on erectile function, being even greater in the DV group. Differences between groups disappear after 6 months.
authors.affiliation: Virgen del Rocío Universitary Hospital, Seville, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: García-Sánchez
authors.affiliation: Virgen del Rocío Universitary Hospital, Seville, Spain.
authors.forename: Ana A Román
authors.initials: AA
authors.lastname: Martín
authors.affiliation: Virgen del Rocío Universitary Hospital, Seville, Spain.
authors.forename: J Manuel
authors.initials: JM
authors.lastname: Conde-Sánchez
authors.affiliation: Virgen del Rocío Universitary Hospital, Seville, Spain.
authors.forename: C Belén
authors.initials: CB
authors.lastname: Congregado-Ruíz
authors.affiliation: Virgen del Rocío Universitary Hospital, Seville, Spain.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Osman-García
authors.affiliation: Virgen del Rocío Universitary Hospital, Seville, Spain.
authors.forename: Rafael A
authors.initials: RA
authors.lastname: Medina-López
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects / Q000379:methods*; D004307:Dose-Response Relationship, Radiation; D007172:Erectile Dysfunction / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods*; D011471:Prostatic Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D011788:Quality of Life; D065287:Robotic Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000209:etiology
keywords: Prostatectomy; Quality of Life; Robotic Surgical Procedures