title: [A Case of Trousseau's Syndrome Caused by CA19-9-Producing Gastric Cancer].
abstract: Trousseau's syndrome is a coagulation disorder occurring in cancer patients. In the present study, we report our experience regarding the pathophysiology and treatment strategies of this syndrome that is caused by CA19-9-producing gastric cancer during long term chemotherapy. A 60s male presented to our clinic; he was found to have a high level of CA19-9. An advanced gastric cancer was identified by gastric scope. A totalgastrectomy was performed. Severalcourses of chemotherapy were administered, and the level of CA19-9 was measured over a long period. Three years and 2 months after the surgery, he presented to the emergency room complaining of acute onset of aphasia and paresis of the extremities. Brain MRI showed multiple cerebral infarctions. He was diagnosed with Trousseau's syndrome. Although decision making is difficult in the treatment of this syndrome, owing to the complex medicalhistory associated with it, it is essentialthat strategies be established for achieving successfultreatment results in the future.
authors.affiliation: Dept. of Surgery, Nara City Hospital.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Nagata
authors.forename: Kei
authors.initials: K
authors.lastname: Nakamura
authors.forename: Akira
authors.initials: A
authors.lastname: Sougawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Mochizuki
authors.forename: Yuen
authors.initials: Y
authors.lastname: Nakase
authors.forename: Shozo
authors.initials: S
authors.lastname: Kitai
authors.forename: Seishirou
authors.initials: S
authors.lastname: Inaba
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000209:etiology*; D018395:CA-19-9 Antigen / Q000096:biosynthesis*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000737:chemistry / Q000150:complications* / Q000188:drug therapy; D013577:Syndrome
chemical_list: D018395:CA-19-9 Antigen