title: Detection of themcr-1Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.
abstract: Since colistin resistance based on the plasmid-encodedmcr-1gene was first described, this resistance gene inEnterobacteriaceaehas been found worldwide. These organisms are typically of heterogeneous genetic background and show exceptional clonal diversity. We describe the first confirmation ofmcr-1in a humanEscherichia colistrain cultured from a surveillance stool sample of an Austrian oncology patient.
authors.affiliation: Institute of Hygiene, Microbiology and Tropical Medicine, National Reference Centre for Nosocomial Infections and Antimicrobial Resistance, Ordensklinikum Linz - Elisabethinen, Linz, Austria.
authors.forename: Rainer
authors.initials: R
authors.lastname: Hartl
authors.affiliation: Institute of Hygiene, Microbiology and Tropical Medicine, National Reference Centre for Nosocomial Infections and Antimicrobial Resistance, Ordensklinikum Linz - Elisabethinen, Linz, Austria.
authors.forename: Heidrun
authors.initials: H
authors.lastname: Kerschner
authors.affiliation: AGES - Austrian Agency for Health and Food Safety, Institute of Medical Microbiology and Hygiene, Vienna, Austria.
authors.forename: Sarah
authors.initials: S
authors.lastname: Lepuschitz
authors.affiliation: AGES - Austrian Agency for Health and Food Safety, Institute of Medical Microbiology and Hygiene, Vienna, Austria.
authors.forename: Werner
authors.initials: W
authors.lastname: Ruppitsch
authors.affiliation: AGES - Austrian Agency for Health and Food Safety, Institute of Medical Microbiology and Hygiene, Vienna, Austria.
authors.forename: Franz
authors.initials: F
authors.lastname: Allerberger
authors.affiliation: Institute of Hygiene, Microbiology and Tropical Medicine, National Reference Centre for Nosocomial Infections and Antimicrobial Resistance, Ordensklinikum Linz - Elisabethinen, Linz, Austria petra.apfalter@jku.at.|Johannes Kepler University, Linz, Austria.
authors.forename: Petra
authors.initials: P
authors.lastname: Apfalter
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001317:Austria; D003091:Colistin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D004927:Escherichia coli Infections / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents; D003091:Colistin
keywords: Austria; Escherichia coli; colistin; mcr-1; resistance