title: Multifunctional Fe3O4/Au core/satellite nanocubes: an efficient chemical synthesis, characterization and functionalization of streptavidin protein.
abstract: A novel and efficient chemical approach for the synthesis of Fe3O4/Au core/satellite nanocubes is reported. In a one-pot reaction, metallic Au nanodots were successfully deposited on the polyvinylpyrrolidone (PVP) functionalized Fe3O4nanocube surface for the fabrication of a core/satellite structure (Fe3O4/Au) by the reduction of HAuCl4using ammonia. Transmission electron microscopy and energy dispersive spectroscopy mapping revealed that small Au nanodots of about 2 nm average size decorated the surface of Fe3O4nanocubes. X-ray diffraction data was used to confirm the formation of both the phases of a cubic inverse spinel structure for Fe3O4and a bcc structure for Au in the core/satellite structure of Fe3O4/Au nanocubes. The magnetic properties of the seed Fe3O4nanocubes and Fe3O4/Au core/satellite nanocubes were measured by using a superconducting quantum interference device at 300 K. For biological application purposes, the as-synthesized Fe3O4/Au core/satellite nanocubes were functionalized by cysteamine followed by successful immobilization of streptavidin protein as confirmed through the fluorescence confocal microscopy images.
authors.affiliation: Department of Emerging Materials Science, DGIST, Daegu 42988, South Korea. cgkim@dgist.ac.kr mohamed@dgist.ac.kr and Ceramics Department, National Research Centre, 12622 El-Bohouth Str., Cairo, Egypt.
authors.forename: Mohamed
authors.identifier: http://orcid.org/0000-0001-6268-6069
authors.initials: M
authors.lastname: Abbas
authors.affiliation: Department of Emerging Materials Science, DGIST, Daegu 42988, South Korea. cgkim@dgist.ac.kr mohamed@dgist.ac.kr.
authors.forename: Sri
authors.initials: S
authors.lastname: RamuluTorati
authors.affiliation: Department of Emerging Materials Science, DGIST, Daegu 42988, South Korea. cgkim@dgist.ac.kr mohamed@dgist.ac.kr.
authors.forename: CheolGi
authors.initials: C
authors.lastname: Kim
mesh_terms: D060326:Chemistry Techniques, Synthetic; D006046:Gold / Q000737:chemistry*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D019809:Streptavidin / Q000737:chemistry*
chemical_list: D058185:Magnetite Nanoparticles; D006046:Gold; D019809:Streptavidin