title: Comorbidity between idiopathic overactive bladder and chronic migraine.
abstract: Objective We tested whether overactive bladder (OAB) and chronic migraine (CM) could be comorbid. Patients and methods CM women, aged 40-69 years, answered a validated OAB questionnaire. Prevalence data were compared with those reported in our country in the general population (GP) using the same questionnaire. Results We interviewed 231 CM women. Eighty-four met OAB criteria. OAB prevalence in CM patients was significantly higher than that found in the GP (36.4% vs. 21.8% in the GP; p = 0.0001). There were 34 CM women aged 40-49 years (34.3% vs. 15.2%; p = 0.001), 35 aged 50-59 years (38.9% vs. 21.7%; p = 0.004) and 15 aged 60-69 years (35.7% vs. 24.5%; p = 0.15) meeting OAB criteria. Seventy-seven (33% vs. 9.9%; p = 0.002) needed more than eight micturitions/24 h, 61 (26.4% vs. 8.1%, p = 0.002) experienced nocturia and 43 (18.6% vs. 8.1%; p = 0.001) urinary incontinence. Conclusion In this exploratory study, at least in women, OAB and CM are comorbid, which suggests shared mechanisms.
authors.affiliation: 1 Service of Neurology, University La Sabana, Bogotá, Colombia.
authors.forename: Marta L
authors.initials: ML
authors.lastname: Ramos
authors.affiliation: 2 Neuroscience Area, Service of Neurology and Faculty of Medicine, University Hospital Central de Asturias, Oviedo, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: García-Cabo
authors.affiliation: 3 Service of Neurology, University Hospital Santiago de Compostela, Spain.
authors.forename: Rogelio
authors.initials: R
authors.lastname: Leira
authors.affiliation: 3 Service of Neurology, University Hospital Santiago de Compostela, Spain.
authors.forename: Clara
authors.initials: C
authors.lastname: Domínguez
authors.affiliation: 4 Service of Neurology, University Hospital Vall d'Hebron, Barcelona, Spain.
authors.forename: Patricia
authors.initials: P
authors.lastname: Pozo-Rosich
authors.affiliation: 4 Service of Neurology, University Hospital Vall d'Hebron, Barcelona, Spain.
authors.forename: Carme
authors.initials: C
authors.lastname: Vila
authors.affiliation: 5 Service of Neurology, Hospital Clínico, Valencia, Spain.
authors.forename: Miguel J
authors.initials: MJ
authors.lastname: Laínez
authors.affiliation: 2 Neuroscience Area, Service of Neurology and Faculty of Medicine, University Hospital Central de Asturias, Oviedo, Spain.|6 Service of Neurology, University Hospital Marqués de Valdecilla and IDIVAL, Santander, Spain.
authors.forename: Julio
authors.initials: J
authors.lastname: Pascual
mesh_terms: D000328:Adult; D000368:Aged; D015897:Comorbidity; D005260:Female; D020773:Headache Disorders / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000453:epidemiology*; D015995:Prevalence; D011795:Surveys and Questionnaires; D053201:Urinary Bladder, Overactive / Q000453:epidemiology*
keywords: Calcitonin gene-related peptide; chronic migraine; comorbidity; overactive bladder