title: Annular lesions of cutaneous sarcoidosis with granulomatous vasculitis.
abstract: Sarcoidosis is known to be involved in diseases with vasculitis as sarcoid vasculitis. However, vasculitis in cutaneous sarcoidal lesions is extremely rare. Here we describe a case of sarcoidosis with multiple annular skin lesions with granulomatous vasculitis. A 62-year-old female was diagnosed with sarcoidosis by chest-abdominal computed tomographic examination and laboratory tests. The skin lesions had appeared on her lower limbs 2 years before. Physical examination showed multiple infiltrated annular eruptions on the lower extremities. A skin biopsy of an area of erythema showed multiple non-caseating epithelioid cell granulomas in the dermis and subcutaneous fat and granulomatous vasculitis with fibrinoid degeneration in the subcutaneous fat. There are two types of vasculitis in sarcoidosis: leukocytoclastic and granulomatous vasculitis. Ulcers and livedo were more common in granulomatous vasculitis than in leukocytoclastic vasculitis. The present case had unique annular skin lesions of sarcoidosis with granulomatous vasculitis.
authors.affiliation: Department of Dermatology, Kansai Medical University, Osaka, Japan.
authors.forename: Kana
authors.initials: K
authors.lastname: Mizuno
authors.affiliation: Department of Dermatology, Kansai Medical University, Osaka, Japan.
authors.forename: Chuyen Thi Hong
authors.initials: CT
authors.lastname: Nguyen
authors.affiliation: Department of Dermatology, Kansai Medical University, Osaka, Japan.
authors.forename: Ikuko
authors.initials: I
authors.lastname: Ueda-Hayakawa
authors.affiliation: Department of Dermatology, Kansai Medical University, Osaka, Japan.
authors.forename: Hiroyuki
authors.identifier: http://orcid.org/0000-0003-2058-7294
authors.initials: H
authors.lastname: Okamoto
mesh_terms: D020405:Dermis / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012507:Sarcoidosis / Q000378:metabolism / Q000473:pathology; D012871:Skin Diseases / Q000378:metabolism / Q000473:pathology; D050151:Subcutaneous Fat / Q000378:metabolism / Q000473:pathology; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000378:metabolism / Q000473:pathology
keywords: annular skin lesions; granulomatous vasculitis; sarcoidosis