title: [Two Cases of Lung Metastasis from Breast Cancer Successfully Treated with Endocrine Therapy].
abstract: We report 2 cases of lung metastasis from breast cancer that were successfully treated with endocrine therapy.Case 1 is a 69-year-old woman with cirrhosis of the liver caused by hepatitis C.She underwent surgery for left breast cancer at the age of 58, and surgery for right breast cancer at the age of 65.Four years later, she was diagnosed with lung metastasis of breast cancer.She received letrozole and the treatment was effective.Because the severity of the pleural effusion increased 3 years later, fulvestrant was subsequently administered.As a result, the patient remained in good health for 1 year.She died 5 years later.Case 2 is a 72-year-old woman who underwent right breast cancer surgery 12 years previously.She complained of respiratory discomfort as a result of right pleural effusion from lung metastasis.She was hospitalized for cancer lymphangitis that had deteriorated.The patient was immediately treated with fulvestrant and her symptoms improved significantly; the pleural effusion also disappeared.Sixteen months later, no recurrence has been observed.
authors.affiliation: Dept. of Surgery, Hasuda Hospital.
authors.forename: Kumi
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Higashi
authors.forename: Ayako
authors.initials: A
authors.lastname: Kamiya
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Takatsuno
authors.forename: Ito
authors.initials: I
authors.lastname: Kondo
authors.forename: Jun
authors.initials: J
authors.lastname: Kaneko
authors.forename: Takeshi
authors.initials: T
authors.lastname: Endo
authors.forename: Shizuaki
authors.initials: S
authors.lastname: Maejima
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004958:Estradiol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D065171:Estrogen Receptor Antagonists / Q000627:therapeutic use*; D005260:Female; D000077267:Fulvestrant; D006801:Humans; D000077289:Letrozole; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D009570:Nitriles / Q000627:therapeutic use; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D065171:Estrogen Receptor Antagonists; D009570:Nitriles; D014230:Triazoles; D000077267:Fulvestrant; D004958:Estradiol; D000077289:Letrozole