title: [A Case of Pancreatic Metastasis of Osteosarcoma Resected Using Laparoscopic Spleen Preserving Distal Pancreatectomy].
abstract: A 44-year-old woman underwent surgical resection and received preoperative and postoperative chemotherapy for conventional osteosarcoma in the right fibular head. Three years later, follow-up PET-CT revealed accumulation ofFDG in the tail ofthe pancreas. Contrast-enhanced computed tomography showed a 13mm well-circumscribed hypovascular tumor. EUS showed a heterogeneous solid tumor, which was diagnosed as metastasis ofosteosarcoma to the pancreas. Laparoscopic spleen preserving distal pancreatectomy(LAP-SPDP)was performed. Pathologically, the tumor was diagnosed as metastasis ofconventional osteosarcoma to the pancreas. Cells from pancreas islet tissue were detected in the tumor, suggesting invasion ofthe tumor into the pancreatic body and surrounding adipose tissue. Although postoperative chemotherapy was administered, lung metastasis was detected 1.1 years after surgery. Laparoscopic partial resection of the lung metastasis was performed, and the patient is still alive. Metastasis ofosteosarcoma to the pancreas is rare, and there is no report oflaparoscopic approach as a treatment. Herein, we report a case with several references.
authors.affiliation: Dept. of Surgery, Division of Hepato-Biliary-Pancreatic Surgery, Kobe University Graduate School of Medicine.
authors.forename: Hirochika
authors.initials: H
authors.lastname: Toyama
authors.forename: Sadaki
authors.initials: S
authors.lastname: Asari
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Goto
authors.forename: Sachio
authors.initials: S
authors.lastname: Terai
authors.forename: Sachiyo
authors.initials: S
authors.lastname: Shirakawa
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Nanno
authors.forename: Takuya
authors.initials: T
authors.lastname: Mizumoto
authors.forename: Takumi
authors.initials: T
authors.lastname: Fukumoto
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Ajiki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kido
authors.forename: Motofumi
authors.initials: M
authors.lastname: Tanaka
authors.forename: Taku
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Hisoka
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Kaori
authors.initials: K
authors.lastname: Kuramitsu
authors.forename: Yonson
authors.initials: Y
authors.lastname: Ku
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery; D005260:Female; D006801:Humans; D010535:Laparoscopy; D012516:Osteosarcoma / Q000556:secondary / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000556:secondary / Q000601:surgery*; D013154:Spleen; D016896:Treatment Outcome