title: Determining the relationship between atherosclerosis and periodontopathogenic microorganisms in chronic periodontitis patients.
abstract: OBJECTIVE
  The aim of this study is to determine the relationship between atherosclerosis and periodontopathogenic microorganisms in chronic periodontitis patients following periodontal treatment.
  
  
  METHODS
  A total of 40 patients were included in the study. 20 of these patients diagnosed with atherosclerosis and chronic periodontitis formed the test group. The remaining 20 patients were systemically healthy patients diagnosed with chronic periodontitis and formed the control group. All patients had nonsurgical periodontal treatment. The periodontopathogenic microorganism levels were determined at baseline and at 6 months in microbial dental plaque samples and WBC, LDL, HDL, PLT, fibrinogen, creatinine and hs-CRP levels were determined by blood samples.
  
  
  RESULTS
  Statistically significant reduction has been achieved in clinical periodontal parameters following non-surgical periodontal treatment in test and control groups. Following periodontal treatment, WBC, LDL, PLT, fibrinogen, creatinine and hs-CRP levels significantly decreased and HDL levels significantly increased in both test and control groups. Similarly, the periodontopathogenic microorganism levels significantly decreased following periodontal treatment in the test and control groups. A statistically significant positive correlation has been determined between the periodontopathogenic microorganism levels and WBC, LDL, PLT, fibrinogen, creatinine, and hs-CRP levels in the test group.
  
  
  CONCLUSIONS
  The association between hs-CRP, WBC, LDL, PLT, fibrinogen, creatinine, and the amount of periodontopathogenic microorganisms indicates the possibility that periodontal treatment could decrease the risk atherosclerosis. More studies must be conducted in order for these results to be supported.
authors.affiliation: a Faculty of Dentistry, Department of Periodontology , Firat University , Elazig , Turkey.
authors.forename: Alihan
authors.initials: A
authors.lastname: Bozoglan
authors.affiliation: b Faculty of Dentistry, Department of Periodontology , Izmir Katip Celebi University , Izmir , Turkey.
authors.forename: Abdullah Seckin
authors.initials: AS
authors.lastname: Ertugrul
authors.affiliation: c Faculty of Medicine, Department of Medical Biology and Genetics , Yuzuncu Yil University , Van , Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Taspınar
authors.affiliation: d Faculty of Dentistry, Department of Orthodontics , Yuzuncu Yil University , Van , Turkey.
authors.forename: Betul
authors.initials: B
authors.lastname: Yuzbasioglu
mesh_terms: D000328:Adult; D050197:Atherosclerosis / Q000097:blood* / Q000150:complications / Q000628:therapy; D002097:C-Reactive Protein / Q000032:analysis; D055113:Chronic Periodontitis / Q000097:blood* / Q000628:therapy; D003774:Dental Plaque Index; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D010512:Periodontal Index; D010518:Periodontitis / Q000097:blood
chemical_list: D018836:Inflammation Mediators; D015850:Interleukin-6; D008075:Lipoproteins, HDL; D005340:Fibrinogen; D002097:C-Reactive Protein
keywords: Atherosclerosis; chronic periodontitis; non-surgical periodontal treatment; periodontopathogenic microorganisms