title: Reductive Homocoupling of Organohalides Using Nickel(II) Chloride and Samarium Metal.
abstract: A homocoupling method for organohalides and organosulfonates promoted by samarium metal and HMPA, and catalyzed by NiCl2has been developed. Various organohalides (benzyl, aryl, heterocyclic, alkenyl and alkyl halides), α-haloacetophenones, and phenyl organosulfonates were tolerated, and the reaction afforded coupling products with high efficiency. Excellent chemoselectivity was exhibited between halides and other groups, such as -COOH, -NO2, halogen, heterocyclic ring, ester, and ketone groups. The stereoselectivity suggested that the reaction mechanism might involve an organosamarium species.
authors.affiliation: State Key Laboratory Base of Eco-chemical Engineering, Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, P. R. China.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Liu
authors.affiliation: State Key Laboratory Base of Eco-chemical Engineering, Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, P. R. China.
authors.forename: Shuhuan
authors.initials: S
authors.lastname: Xiao
authors.affiliation: State Key Laboratory Base of Eco-chemical Engineering, Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, P. R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Qi
authors.affiliation: State Key Laboratory Base of Eco-chemical Engineering, Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, P. R. China.
authors.forename: Feng
authors.initials: F
authors.lastname: Du
keywords: halides; homocoupling; nickel(II) chloride; organosulfonate; samarium