title: Decrease of respiratory events in patients with obstructive sleep apnea-hypopnea syndrome using a mandibular advancement device assessed with split night polysomnography.
abstract: BACKGROUND
  Mandibular advancement device (MAD) may represent a feasible choice in the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS), in well selected patients.
  
  
  OBJECTIVE
  The aim of this study is to assess the efficacy of MAD in patients with OSAHS, using split night polysomnography (SNP).
  
  
  METHODS
  We performed an auto controlled clinical trial to assess the efficacy of MAD in 30 patients with snoring and OSAHS. Clinical evaluation was made every 2 weeks to adjust treatment and observe changes in clinical symptoms. Three-months after placement of the MAD, a SNP was performed, using the MAD in the second half of the night, in order to compare the respiratory results.
  
  
  RESULTS
  SNP show significant changes with use of MAD (p<0.05) such as: Decrease in Snore index (from 159.95 to 32.46/h) and in Apnea-hypopnea index (AHI, from 22.45 to 4.63/h), increase in oxygen saturation (SaO2, from 89.98% to 91.39%) and somnolence improvement, using the Epworth Sleepiness Scale (from 14.4 to 4.6 points).
  
  
  CONCLUSIONS
  Our data supports that the use of MAD is an alternative in the management of OSAHS, in well selected patients, used in a multidisciplinary fashion, and evaluated using a SNP.
authors.affiliation: Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico.
authors.forename: Emma
authors.initials: E
authors.lastname: García-Campos
authors.affiliation: Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico.
authors.forename: Alberto
authors.initials: A
authors.lastname: Labra
authors.affiliation: Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico.
authors.forename: Lourdes
authors.initials: L
authors.lastname: Galicia-Polo
authors.affiliation: Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico.
authors.forename: Francisco
authors.initials: F
authors.lastname: Sánchez-Narváez
authors.affiliation: Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico.
authors.forename: Reyes
authors.initials: R
authors.lastname: Haro
authors.affiliation: Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico.
authors.forename: Ulises
authors.initials: U
authors.lastname: Jiménez
authors.affiliation: Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico.
authors.forename: Adrián
authors.initials: A
authors.lastname: Poblano
keywords: Mandibular advancement device; Obstructive sleep apnea; Polysomnography