title: French updated recommendations in Stage I to III melanoma treatment and management.
abstract: As knowledge continues to develop, regular updates are necessary concerning recommendations for practice. The recommendations for the management of melanoma stages I to III were drawn up in 2005. At the request of the Société Française de Dermatologie, they have now been updated using the methodology for recommendations proposed by the Haute Autorité de Santé in France. In practice, the principal recommendations are as follows: for staging, it is recommended that the 7th edition of AJCC be used. The maximum excision margins have been reduced to 2 cm. Regarding adjuvant therapy, the place of interferon has been reduced and no validated emerging medication has yet been identified. Radiotherapy may be considered for patients in Stage III at high risk of relapse. The sentinel lymph node technique remains an option. Initial examination includes routine ultrasound as of Stage II, with other examinations being optional in stages IIC and III. A shorter strict follow-up period (3 years) is recommended for patients, but with greater emphasis on imaging.
authors.affiliation: Dermatology Department, CHU Montpellier.
authors.forename: B
authors.initials: B
authors.lastname: Guillot
authors.affiliation: Dermatology Department, CHU Dijon.
authors.forename: S
authors.initials: S
authors.lastname: Dalac
authors.affiliation: Laboratory of Biochemistry, CHU Nantes.
authors.forename: M G
authors.initials: MG
authors.lastname: Denis
authors.affiliation: Dermatology Department, CHU Rennes.
authors.forename: A
authors.initials: A
authors.lastname: Dupuy
authors.affiliation: Laboratory of Pathology, AP-HP Ambroise Paré Hospital, Boulogne, France.
authors.forename: J F
authors.initials: JF
authors.lastname: Emile
authors.affiliation: Laboratory of Pathology, Centre Léon Bérard Lyon.
authors.forename: A
authors.initials: A
authors.lastname: De La Fouchardiere
authors.affiliation: Department of Nuclear medicine, CHU Bordeaux.
authors.forename: E
authors.initials: E
authors.lastname: Hindie
authors.affiliation: Dermatology Department, CH Pau.
authors.forename: T
authors.initials: T
authors.lastname: Jouary
authors.affiliation: Department of Radiology, Institut Gustave Roussy Villejuif.
authors.forename: N
authors.initials: N
authors.lastname: Lassau
authors.affiliation: Department of Radiotherapy, Centre Oscar Lambret Lille.
authors.forename: X
authors.initials: X
authors.lastname: Mirabel
authors.affiliation: Institut Curie, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Piperno Neumann
authors.affiliation: 1 Avenue du 6 Juin, 1945, 14000 Caen, France.
authors.forename: S
authors.initials: S
authors.lastname: De Raucourt
authors.affiliation: Louvain Catholic University, Brussels, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Vanwijck
mesh_terms: D017024:Chemotherapy, Adjuvant / Q000592:standards; D046169:Dermoscopy; D005602:France; D005838:Genotype; D000072662:Margins of Excision; D008545:Melanoma / Q000175:diagnosis / Q000235:genetics / Q000556:secondary / Q000628:therapy; D009367:Neoplasm Staging; D011159:Population Surveillance / Q000379:methods; D018714:Radiotherapy, Adjuvant / Q000592:standards; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy