title: [A Case of Small Intestinal Gastrointestinal Stromal Tumor(GIST)with Synchronous Colonic Cancer and Gastric Cancer at a Different Time].
abstract: The patient was a 70-year-old woman with a gastrointestinalstromaltumor (GIST)of the small intestine and synchronous colonic cancer, who underwent laparoscopic right colectomy and resection of the small intestine. We started imatinib therapy because GIST belongs to a high-risk group, according to the modified Fletcher classification. Gastric cancer was diagnosed 2 years after the start of imatinib therapy. Only 4 of the 12 GIST cases seen at our institution over the last 5 years were complicated by another cancer. This is the first case of GIST in which 2 other cancers occurred at both the same and different times. We suggest that imatinib might be a factor in the development of gastric cancer.
authors.affiliation: Dept. of Surgery, Arao Mumicipal Hospital.
authors.forename: Yukika
authors.initials: Y
authors.lastname: Tsukamoto
authors.forename: Hisami
authors.initials: H
authors.lastname: Oshima
authors.forename: Takashi
authors.initials: T
authors.lastname: Katsumori
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Hamaguchi
authors.forename: Shinichi
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iwanaga
authors.forename: Susumu
authors.initials: S
authors.lastname: Ohkawara
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000601:surgery; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001063:Appendiceal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007078:Ileal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D000068877:Imatinib Mesylate / Q000627:therapeutic use; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate