title: Evaluation of the Efficacy and Safety of the New Susanna Glaucoma Drainage Device in Refractory Glaucomas: Short-term Results.
abstract: OBJECTIVE
  To assess the efficacy and safety of the new Susanna glaucoma drainage device (SGDD) in patients with neovascular and refractory glaucomas.
  
  
  METHODS
  In this prospective study, patients with neovascular glaucoma or refractory glaucomas (defined as eyes with previous trabeculectomy failure) were enrolled. All eyes had to have intraocular pressure (IOP) above 21 mm Hg despite maximum tolerated topical medication, or recent documentation of anatomic and/or functional progression. Patients underwent glaucoma surgery with the new SGDD in a standardized manner. Postoperative visits were performed at days 1 and 7; months 1, 3, and 6; and every 6 months thereafter. Preoperative and postoperative IOP, number of antiglaucoma medications, surgical complications, and any subsequent related events were recorded. Success criteria were: (I) IOP≥6 and ≤21 mm Hg; (II) IOP≥6 and ≤18 mm Hg. Each criterion was classified as complete (without medication) or qualified (with medication).
  
  
  RESULTS
  A total of 58 patients with a mean age of 64.3±11.5 years were included [19 with neovascular glaucoma (group 1) and 39 with failure of first trabeculectomy (group 2)]. Overall, mean follow-up was 7.1±3.8 months, and mean IOP was reduced from 31.5±1.6 (range, 18 to 68) mm Hg to 12.6±0.7 (range, 2 to 28) mm Hg at the last follow-up visit (P<0.01). The mean number of antiglaucoma medications used was reduced from 3.4±0.9 to 1.4±1.5 (P<0.01). At 6 months postoperatively, qualified success rates for groups 1 and 2 were 73% and 86%, respectively (considering the stricter criterion). Main complications were 2 cases of conjunctival erosion and 2 cases of late hypotony.
  
  
  CONCLUSIONS
  Our initial findings suggest that the new SGDD is an effective alternative for managing neovascular and refractory glaucomas, with minor postoperative complications in the short-term.
authors.affiliation: *Department of Ophthalmology, Federal University of São Paulo §Department of Ophthalmology, University of São Paulo, São Paulo †Department of Ophthalmology, São José University Hospital, Belo Horizonte ‡Brazilian Institute of Ophthalmology and Blindness Prevention (IBOPC), Salvador, Brazil.
authors.forename: Luis G
authors.initials: LG
authors.lastname: Biteli
authors.forename: Tiago S
authors.initials: TS
authors.lastname: Prata
authors.forename: Carolina P B
authors.initials: CP
authors.lastname: Gracitelli
authors.forename: Fábio N
authors.initials: FN
authors.lastname: Kanadani
authors.forename: Flávia
authors.initials: F
authors.lastname: Villas Boas
authors.forename: Marcelo
authors.initials: M
authors.lastname: Hatanaka
authors.forename: Augusto
authors.initials: A
authors.lastname: Paranhos Junior
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D005260:Female; D005901:Glaucoma / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D020327:Glaucoma Drainage Implants / Q000009:adverse effects; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000601:surgery; D011446:Prospective Studies; D019919:Prosthesis Implantation; D014130:Trabeculectomy; D017211:Treatment Failure
chemical_list: D000959:Antihypertensive Agents