title: [A new toolbox for genome editing].
abstract: A new approach, based on the use of peptide nucleic acid molecules to form triple helices and promote locus-specific recombination, demonstrates potential for in vivo gene correction at clinically significant levels and may provide a promising avenue for gene therapy.
authors.affiliation: UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d'adultes la Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05, France - CoReBio PACA, case 901, parc scientifique de Luminy, 13288 Marseille Cedex 09, France.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Jordan
mesh_terms: D064113:CRISPR-Cas Systems; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D000072669:Gene Editing / Q000379:methods* / Q000639:trends; D018390:Gene Targeting; D015316:Genetic Therapy / Q000379:methods; D023281:Genomics / Q000379:methods / Q000639:trends; D006801:Humans; D016297:Mutagenesis, Site-Directed / Q000379:methods*; D020135:Peptide Nucleic Acids / Q000502:physiology*
chemical_list: C505032:CFTR protein, human; D020135:Peptide Nucleic Acids; D019005:Cystic Fibrosis Transmembrane Conductance Regulator