title: Neonatal Respiratory Failure Caused by Congenital Diffuse Intrinsic Pontine Glioma.
abstract: The authors present a case of diffuse intrinsic pontine glioma presenting in a newborn with stridor and respiratory distress that progressed to respiratory failure. Magnetic resonance imaging (MRI) of the brain revealed findings compatible with the diagnosis of diffuse intrinsic pontine glioma. The family pursued palliative care and postmortem examination confirmed WHO grade III astrocytoma.
authors.affiliation: 1 Neonatology, Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
authors.forename: Katie M
authors.initials: KM
authors.lastname: Satrom
authors.affiliation: 2 Pediatric Hematology-Oncology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: Rachel A
authors.initials: RA
authors.lastname: Phelan
authors.affiliation: 3 Pediatric Hematology-Oncology, Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Moertel
authors.affiliation: 4 Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA.
authors.forename: H
authors.initials: H
authors.lastname: Brent Clark
authors.affiliation: 1 Neonatology, Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
authors.forename: Dana E
authors.initials: DE
authors.lastname: Johnson
authors.affiliation: 1 Neonatology, Department of Pediatrics, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
authors.forename: Thomas N
authors.initials: TN
authors.lastname: George
mesh_terms: D020295:Brain Stem Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D003933:Diagnosis; D005910:Glioma / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D012131:Respiratory Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology*; D009418:S100 Proteins / Q000378:metabolism
chemical_list: D009418:S100 Proteins
keywords: brain stem; glioma; neonatal; respiratory distress; stridor