title: Preoperative weight loss program targeting women with overweight and hypertrophy of the breast - a pilot study.
abstract: Among women with hypertrophic breasts, the clear majority are overweight or obese. Owing to increased risk of complications, women with a body mass index (BMI) above 25 kg m-2are precluded from reduction mammaplasty. The primary aim was to investigate if intensive weight loss could ready women with overweight for breast reduction surgery. Six women, all overweight [BMI 30.9 {28.5; 35.8} kg m-2] with symptomatic hypertrophy of the breast, were included a 12-week weight loss program. All women desired reduction mammaplasty and were motivated for preoperational weight loss. The first 8 weeks consisted of a formula-based diet supplying 800 kcal daily, in the subsequent 4 weeks regular foods were reintroduced increasing the intake to 1200 kcal daily. Five women completed the trial, and achieved a median (range) weight loss of 10.2 (6.5; 19) kg. Initial breast volume was 1100-2500 mL per breast, this was reduced by 300 (200; 500) mL after the intervention; equivalent to approximately 19%. Waist, hip, upper arm and thorax circumference were significantly reduced following weight loss. At end of study, all the women still suffered from symptomatic breast hypertrophy to substantiate reduction mammaplasty. Surgeries were performed 2 months thereafter. A 12-week intensive preoperative weight loss program enabled women with obesity for breast reduction surgery. Breast size was reduced proportionally more than total weight loss among women with hypertrophy.
authors.affiliation: Clinical Nutrition Research Unit, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark.
authors.forename: N R W
authors.initials: NR
authors.lastname: Geiker
authors.affiliation: Department of Plastic Surgery, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark.
authors.forename: J
authors.initials: J
authors.lastname: Horn
authors.affiliation: Clinical Nutrition Research Unit, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark.|Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
authors.forename: A
authors.initials: A
authors.lastname: Astrup
mesh_terms: D000328:Adult; D001940:Breast / Q000002:abnormalities* / Q000473:pathology* / Q000601:surgery; D004038:Diet, Reducing / Q000379:methods*; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000209:etiology / Q000601:surgery*; D016462:Mammaplasty; D008875:Middle Aged; D009929:Organ Size; D050177:Overweight / Q000150:complications / Q000178:diet therapy*; D010865:Pilot Projects; D057234:Preoperative Period; D016896:Treatment Outcome; D015431:Weight Loss; D061217:Weight Reduction Programs / Q000379:methods
keywords: Hypertrophy; obesity; overweight; reduction mammoplasty