title: Two new flavans from the roots of Dianella ensifolia (L.) DC.
abstract: Two new flavans, named (2S)-2',4'-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2'-hydroxy-4',7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2 displayed cytotoxic eﬀects against cancer cell lines MDA-MB-231, B16-F10, HCT116 and A549.
authors.affiliation: a Department of Medical Science , Shunde Polytechnic , Shunde , China.
authors.forename: Ben-Qin
authors.initials: BQ
authors.lastname: Tang
authors.affiliation: a Department of Medical Science , Shunde Polytechnic , Shunde , China.
authors.forename: Shu-Sheng
authors.initials: SS
authors.lastname: Huang
authors.affiliation: b State Key Laboratory of Quality Research in Chinese Medicine , Institute of Chinese Medical Sciences, University of Macau , Macau SAR , China.
authors.forename: Ye-Er
authors.initials: YE
authors.lastname: Liang
authors.affiliation: c Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , China.
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Sun
authors.affiliation: a Department of Medical Science , Shunde Polytechnic , Shunde , China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Ma
authors.affiliation: a Department of Medical Science , Shunde Polytechnic , Shunde , China.
authors.forename: Bao
authors.initials: B
authors.lastname: Zeng
authors.affiliation: b State Key Laboratory of Quality Research in Chinese Medicine , Institute of Chinese Medical Sciences, University of Macau , Macau SAR , China.
authors.forename: Simon Ming-Yuen
authors.initials: SM
authors.lastname: Lee
authors.affiliation: a Department of Medical Science , Shunde Polytechnic , Shunde , China.
authors.forename: Jian-Lin
authors.initials: JL
authors.lastname: Lu
mesh_terms: D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology; D016923:Cell Death / Q000187:drug effects; D045744:Cell Line, Tumor; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D005419:Flavonoids
keywords: Dianella ensifolia; cytotoxicity; flavans