title: Factors that Explain the Cancer-Related Insomnia.
abstract: A better understanding of cancer related insomnia and its relationship with other associated factors is necessary to improve its management. To clarify the relationship between insomnia and treatment related variables, sociodemographic data, health related fitness, pain, anxiety, and depression in breast cancer patients. One hundred twenty-three patients participated in this cross-sectional study. As a primary variable was insomnia using The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 version. Other variables included: stage of treatment, type of treatment, multiple sit to stand test, trunk curl test, 6-min walk test, back muscle strength test, the Brief Pain Inventory short form and the Hospital Anxiety and Depression Scale. Insomnia was negatively associated with the treatment stage (p = 0.01), the 6-min walk test (p = 0.01) and the back muscle strength test (p = 0.01), while it was positively associated with the type of treatment (p = 0.01) and the multiple sit-to-stand test (p = 0.05). In addition, higher levels of insomnia were associated with higher scores on the Brief Pain Inventory short form (p = 0.01) and the Hospital Anxiety and Depression Scale (p = 0.01). Anxiety, type of treatment, back muscle strength, pain severity and stage of treatment were predictors of insomnia, and when they were combined they explained 51.2% of insomnia in our sample. The variability in insomnia related breast cancer is explained by anxiety, type of treatment, pain, treatment stage, and back muscle strength. Clinicians should take these results into account when generating cancer care programs to control pain and health-related-fitness (Registration of Trials NCT01801527).
authors.affiliation: Instituto de Investigación Biosanitaria de Granada, Granada, Spain.|Department of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
authors.forename: Noelia
authors.initials: N
authors.lastname: Galiano-Castillo
authors.affiliation: Instituto de Investigación Biosanitaria de Granada, Granada, Spain.|Department of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Arroyo-Morales
authors.affiliation: Department of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.|Physical Medicine and Rehabilitation Department, Clinico Universitario San Cecilio, Granada, Spain.
authors.forename: Angélica
authors.initials: A
authors.lastname: Ariza-Garcia
authors.affiliation: Instituto de Investigación Biosanitaria de Granada, Granada, Spain.|Department of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
authors.forename: Carolina
authors.initials: C
authors.lastname: Fernández-Lao
authors.affiliation: Department of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
authors.forename: Andrés J
authors.initials: AJ
authors.lastname: Fernández-Fernández
authors.affiliation: Instituto de Investigación Biosanitaria de Granada, Granada, Spain.|Department of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: Cantarero-Villanueva
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety; D001943:Breast Neoplasms / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D010147:Pain Measurement; D011788:Quality of Life; D007319:Sleep Initiation and Maintenance Disorders / Q000523:psychology*; D013030:Spain; D011795:Surveys and Questionnaires
keywords: breast cancer; chemotherapy; insomnia related cancer; survival