title: Effectiveness and Tolerability of Colesevelam HCl for Accelerated Elimination of Teriflunomide in Healthy Participants.
authors.affiliation: Sanofi R&D, Chilly-Mazarin, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Lunven
authors.affiliation: Sanofi US, Bridgewater, NJ, USA.
authors.forename: Zuyu
authors.initials: Z
authors.lastname: Guo
authors.affiliation: Sanofi US, Bridgewater, NJ, USA.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Turpault
authors.affiliation: Sanofi R&D, Chilly-Mazarin, France.
authors.forename: Astrid
authors.initials: A
authors.lastname: Delfolie
authors.affiliation: Biotrial, Rennes, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Fauchoux
authors.affiliation: Sanofi Genzyme, Cambridge, MA, USA.
authors.forename: Timothy
authors.initials: T
authors.lastname: Turner
authors.affiliation: Sanofi Genzyme, Cambridge, MA, USA.
authors.forename: Francesca
authors.initials: F
authors.lastname: Baldinetti
mesh_terms: D000328:Adult; D000924:Anticholesteremic Agents / Q000008:administration & dosage / Q000097:blood; D000069472:Colesevelam Hydrochloride / Q000008:administration & dosage* / Q000097:blood*; D003437:Crotonates / Q000008:administration & dosage* / Q000097:blood*; D004334:Drug Administration Schedule; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D006885:Hydroxybutyrates; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects* / Q000502:physiology; D009570:Nitriles; D014052:Toluidines / Q000008:administration & dosage* / Q000097:blood*; D016896:Treatment Outcome
chemical_list: D000924:Anticholesteremic Agents; D003437:Crotonates; D006885:Hydroxybutyrates; D009570:Nitriles; D014052:Toluidines; C527525:teriflunomide; D000069472:Colesevelam Hydrochloride
keywords: accelerated elimination procedure; colesevelam HCl; pharmacokinetics; teriflunomide