title: A new 5(6→7)abeo-sterol from Podocarpus fleuryi.
abstract: A new 5(6→7)abeo-sterol, podosterol (1), together with 20 known compounds, were isolated from the leaves of Podocarpus fleuryi. Their structures were elucidated by means of extensive spectroscopic analysis. Podosterol was assessed for its cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW-480), and the result showed that it had no activity.
authors.affiliation: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming 650500 , China.
authors.forename: Juan
authors.initials: J
authors.lastname: Liu
authors.affiliation: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming 650500 , China.
authors.forename: Zhao-Hong
authors.initials: ZH
authors.lastname: Gao
authors.affiliation: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming 650500 , China.
authors.forename: Ji-Chun
authors.initials: JC
authors.lastname: Wu
authors.affiliation: a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming 650500 , China.
authors.forename: Ye-Gao
authors.initials: YG
authors.lastname: Chen
mesh_terms: D000072283:A549 Cells; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D061986:MCF-7 Cells; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D013261:Sterols / Q000737:chemistry / Q000302:isolation & purification*; D064028:Tracheophyta / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D013261:Sterols; C000623066:podosterol
keywords: Podocarpaceae; Podocarpus fleuryi; abeo-sterol; podosterol