title: UV Photofunctionalization Effect on Bone Graft in Critical One-Wall Defect around Implant: A Pilot Study in Beagle Dogs.
abstract: The purpose of this study was to compare and evaluate, through histomorphometric and radiological analysis, the effects of UV photofunctionalization on an implant placed over a critical defect area with and without a bone graft. Four female beagle dogs were first divided into control and bone graft groups. Each group was then subdivided into UV-treated and UV-untreated groups. The mandibular premolars in each dog were extracted. 12 weeks after extraction, implants were placed according to the condition of each group. Four and 12 weeks after implantation on left and right mandible, the dogs were sacrificed. The specimens were prepared for histomorphometric and micro-computed tomographic analysis. In both 4-week and 12-week groups, UV-treated implant surfaces showed better osseointegration than SA implant surfaces. Also, with implant surfaces placed over the critical defect with bone graft, UV photofunctionalization increased bone-to-implant contact (BIC) and new bone formation at the initial stage (4 weeks). Based on the results of this study, it can be suggested that UV photofunctionalization on the surface of implants placed over large critical defects with bone graft aids initial osseointegration and osteogenesis.
authors.affiliation: Department of Prosthodontics, Oral Science Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
authors.forename: Min-Young
authors.initials: MY
authors.lastname: Kim
authors.affiliation: Department of Prosthodontics, Oral Science Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
authors.forename: Hyunmin
authors.identifier: 0000-0002-9479-3587
authors.initials: H
authors.lastname: Choi
authors.affiliation: Department of Prosthodontics, Oral Science Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
authors.forename: Jae-Hoon
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Prosthodontics, Oral Science Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
authors.forename: Jee-Hwan
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Division in Anatomy and Developmental Biology, Department of Oral Biology, Oral Science Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
authors.forename: Han-Sung
authors.initials: HS
authors.lastname: Jung
authors.affiliation: Department of Dental Technology, School of Medical and Public Health, Kyungdong University, Wonju, Gangwon-do, Republic of Korea.
authors.forename: Jae-Hong
authors.identifier: 0000-0002-2679-8802
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Prosthodontics, Oral Science Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
authors.forename: Young-Bum
authors.initials: YB
authors.lastname: Park
authors.affiliation: Department of Prosthodontics, Oral Science Research Center, BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
authors.forename: Hong-Seok
authors.identifier: 0000-0001-8118-8145
authors.initials: HS
authors.lastname: Moon
mesh_terms: D000818:Animals; D016025:Bone Transplantation / Q000379:methods*; D000069343:Bone-Implant Interface / Q000473:pathology / Q000528:radiation effects* / Q000601:surgery; D003131:Combined Modality Therapy / Q000379:methods; D015921:Dental Implants; D004285:Dogs; D005260:Female; D008334:Mandible / Q000473:pathology* / Q000528:radiation effects / Q000601:surgery*; D010865:Pilot Projects; D016896:Treatment Outcome; D014467:Ultraviolet Therapy / Q000379:methods*
chemical_list: D015921:Dental Implants