title: Novel EGFR Exon 18 (G721R) Mutation in a Patient with Non-Small Cell Lung Carcinoma with Lack of Response to Afatinib.
authors.affiliation: Department of Hematology and Oncology, Cleveland Clinic, Cleveland, OH. Electronic address: velchev@ccf.org.
authors.forename: Vamsidhar
authors.initials: V
authors.lastname: Velcheti
authors.affiliation: Department of Internal Medicine, Cleveland Clinic, Cleveland, OH.
authors.forename: Monica
authors.initials: M
authors.lastname: Khunger
authors.affiliation: Department of Translational Hematology Oncology Research Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH.
authors.forename: Mohamed E
authors.initials: ME
authors.lastname: Abazeed
mesh_terms: D000077716:Afatinib; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics* / Q000473:pathology; D019008:Drug Resistance, Neoplasm; D066246:ErbB Receptors / Q000235:genetics* / Q000378:metabolism; D005091:Exons; D006801:Humans; D008175:Lung Neoplasms / Q000201:enzymology / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011799:Quinazolines / Q000494:pharmacology
chemical_list: D011799:Quinazolines; D000077716:Afatinib; C512478:EGFR protein, human; D066246:ErbB Receptors