title: Non-granulomatous myositis in a patient with ulcerative colitis who showed symptoms resembling gastrocnemius myalgia syndrome.
abstract: The patient was a 36-year-old man. His initial symptom was bilateral thigh and calf pain. When he developed ulcerative colitis in the following year, he also noticed wasting of the calf muscles. The clinical feature is similar to gastrocnemius myalgia syndrome, although the left upper limb was also involved. A high-intensity lesion in the left calf and soleus muscles was observed on MRI, which was lead to the diagnosis of non-granulomatous myositis with infiltration of CD68-positive cells based on muscle biopsy. After steroids were administered, his pain subsided. Evaluation with needle EMG, MRI, and muscle biopsy is important when muscle pain accompanies inflammatory bowel disease.
authors.affiliation: Department of Neurology, Kansai Electric Power Hospital.
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Manabu
authors.initials: M
authors.lastname: Inoue
authors.forename: Naoko
authors.initials: N
authors.lastname: Tachibana
authors.forename: Koji
authors.initials: K
authors.lastname: Tsuzaki
authors.forename: Yoko
authors.initials: Y
authors.lastname: Shibata
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Hamano
mesh_terms: D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D003093:Colitis, Ulcerative / Q000150:complications*; D003937:Diagnosis, Differential; D004576:Electromyography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D018482:Muscle, Skeletal / Q000378:metabolism / Q000473:pathology; D063806:Myalgia; D009220:Myositis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000008:administration & dosage; D020551:Pulse Therapy, Drug; D013577:Syndrome; D016896:Treatment Outcome; D000097382:CD68 Molecule
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D015415:Biomarkers; D008775:Methylprednisolone; D011239:Prednisolone; C067980:CD68 antigen, human; D000097382:CD68 Molecule