title: Understanding therapeutic targets in thrombotic thrombocytopenic purpura.
authors.affiliation: Service d'hématologie biologique and EA3518-Institut universitaire d'hématologie, Groupe Hospitalier Saint Louis-Lariboisière, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, 2 rue Ambroise Paré, 75010, Paris, France.
authors.forename: Bérangère S
authors.initials: BS
authors.lastname: Joly
authors.affiliation: Laboratory for Thrombosis Research, IRF Life Sciences, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.
authors.forename: Karen
authors.initials: K
authors.lastname: Vanhoorelbeke
authors.affiliation: Service d'hématologie biologique and EA3518-Institut universitaire d'hématologie, Groupe Hospitalier Saint Louis-Lariboisière, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, 2 rue Ambroise Paré, 75010, Paris, France. agnes.veyradier@aphp.fr.
authors.forename: Agnès
authors.initials: A
authors.lastname: Veyradier
mesh_terms: D000071120:ADAMTS13 Protein / Q000172:deficiency / Q000276:immunology / Q000627:therapeutic use; D001323:Autoantibodies / Q000097:blood / Q000187:drug effects / Q000276:immunology; D002986:Clinical Trials as Topic; D003422:Critical Care / Q000379:methods; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D007362:Intensive Care Units; D010951:Plasma Exchange; D011697:Purpura, Thrombotic Thrombocytopenic / Q000097:blood / Q000276:immunology / Q000401:mortality / Q000628:therapy; D012008:Recurrence
chemical_list: D001323:Autoantibodies; D007155:Immunologic Factors; D000071120:ADAMTS13 Protein
keywords: ADAMTS13 Deficiency; Eculizumab; High Molecular Weight Multimers; Thrombotic Thrombocytopenic Purpura; Thrombotic Thrombocytopenic Purpura Patient