title: Comprehensive Annotation of Mature Peptides and Genotypes for Zika Virus.
abstract: The rapid spread of Zika virus (ZIKV) has caused much concern in the global health community, due in part to a link to fetal microcephaly and other neurological illnesses. While an increasing amount of ZIKV genomic sequence data is being generated, an understanding of the virus molecular biology is still greatly lacking. A significant step towards establishing ZIKV proteomics would be the compilation of all proteins produced by the virus, and the resultant virus genotypes. Here we report for the first time such data, using new computational methods for the annotation of mature peptide proteins, genotypes, and recombination events for all ZIKV genomes. The data is made publicly available through the Virus Pathogen Resource at www.viprbrc.org.
authors.affiliation: Vecna Technologies, Inc., Greenbelt, Maryland, United States of America.
authors.forename: Guangyu
authors.initials: G
authors.lastname: Sun
authors.affiliation: Vecna Technologies, Inc., Greenbelt, Maryland, United States of America.
authors.forename: Christopher N
authors.identifier: http://orcid.org/0000-0002-1051-5767
authors.initials: CN
authors.lastname: Larsen
authors.affiliation: Center for Comparative Medicine and the Department of Pathology, Microbiology & Immunology, University of California, Davis, Davis, California, United States of America.
authors.forename: Nicole
authors.initials: N
authors.lastname: Baumgarth
authors.affiliation: Northrop Grumman Health Solutions, Rockville, Maryland, United States of America.
authors.forename: Edward B
authors.initials: EB
authors.lastname: Klem
authors.affiliation: J. Craig Venter Institute, La Jolla, California, United States of America.|Department of Pathology, University of California, San Diego, San Diego, California, United States of America.|Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
authors.forename: Richard H
authors.initials: RH
authors.lastname: Scheuermann
mesh_terms: D005814:Genes, Viral; D005838:Genotype; D006801:Humans; D010455:Peptides / Q000378:metabolism*; D011634:Public Health; D014764:Viral Proteins / Q000378:metabolism*; D000071244:Zika Virus / Q000235:genetics* / Q000378:metabolism*; D000071243:Zika Virus Infection / Q000821:virology*
chemical_list: D010455:Peptides; D014764:Viral Proteins