title: [Long-Term Survival of a Patient with Sigmoid Colon Cancer with Multiple Visceral Metastases].
abstract: A 66-year-old woman underwent total pelvic exenteration for a pelvic tumor. The pathological diagnosis was sigmoid colon cancer T4b(in the small intestine, uterus, and vagina), N0, M0, Stage II . The patient was treated with XELOX for 6 months as adjuvant chemotherapy and was then treated with IRIS for another 6 months. Brain metastasis developed in the left occipital lobe after 12 months, and she underwent craniotomy and enucleation of the tumor. Liver metastasis and peritoneal dissemination metastasis developed 16 months after her initial diagnosis. The patient underwent re-craniotomy and radiotherapy for recurrence of the brain metastasis 18 months after diagnosis and started taking TAS-102 3 months later. She began treatment with CPT-11 plus panitumumab 24 months after diagnosis, and the dose was increased 9 months later(ie, 35 months after the initial diagnosis). The patient remains alive 42 months after surgery.
authors.affiliation: Dept. of Surgery, Nara Medical University.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Naoto
authors.initials: N
authors.lastname: Nishigori
authors.forename: Fumikazu
authors.initials: F
authors.lastname: Koyama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ueda
authors.forename: Takashi
authors.initials: T
authors.lastname: Inoue
authors.forename: Keijirou
authors.initials: K
authors.lastname: Kawasaki
authors.forename: Shinsaku
authors.initials: S
authors.lastname: Obara
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nakamoto
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Hisao
authors.initials: H
authors.lastname: Fujii
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Nakajima
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D012008:Recurrence; D012811:Sigmoid Neoplasms / Q000473:pathology / Q000628:therapy*; D013997:Time Factors