title: [A Case of Advanced Hepatocellular Carcinoma, Its Disease Progression Could Be Controlled by Multimodal Treatment].
abstract: The patient was a 73-year-old man, diagnosed with advanced huge hepatocellular carcinoma with a tumor thrombus extending into the inferior vena cava and extrahepatic metastases. Radiation therapy(50 Gy)was applied for the bone metastases, primary tumor, and tumor thrombus, and the patient received a cisplatin transcatheter arterial infusion(100mg/ body, 5 courses). Sorafenib was administered orally once the local lesion was under control. The tumor showed a partial response according to the RECIST criteria, but the tumor thrombus in the inferior vena cava almost disappeared. The presence of a tumor thrombus in the inferior vena cava must be regarded as an oncologic emergency. Acisplatin transcatheter arterial infusion and radiation therapy may be treatment options for unresectable cases.
authors.affiliation: Dept. of Surgery, Nara Medical University.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Takeo
authors.initials: T
authors.lastname: Nomi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Hokuto
authors.forename: Ichirou
authors.initials: I
authors.lastname: Yamato
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yasuda
authors.forename: Shinsaku
authors.initials: S
authors.lastname: Obara
authors.forename: Chihiro
authors.initials: C
authors.lastname: Kawaguchi
authors.forename: Shoichi
authors.initials: S
authors.lastname: Kinoshita
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nishiwada
authors.forename: Minako
authors.initials: M
authors.lastname: Nagai
authors.forename: Takahiro
authors.initials: T
authors.lastname: Akahori
authors.forename: Takatsugu
authors.initials: T
authors.lastname: Yamada
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sho
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Kanehiro
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Nakajima
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D018450:Disease Progression; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D008297:Male; D009536:Niacinamide / Q000008:administration & dosage / Q000031:analogs & derivatives; D010671:Phenylurea Compounds / Q000008:administration & dosage; D000077157:Sorafenib; D016896:Treatment Outcome
chemical_list: D010671:Phenylurea Compounds; D009536:Niacinamide; D000077157:Sorafenib; D002945:Cisplatin