title: Fatigue analysis of tympanic membrane after ossiculoplasty.
abstract: CONCLUSIONS
  A tentative conclusion was made that the finite element method can be used to investigate the fatigue life of the tympanic membrane after ossiculoplasty; the main reason of the extrusion of the tympanic membrane may not be blamed to the fatigue mechanism under normal sound pressure.
  
  
  OBJECTIVE
  This study was to investigate the extrusion of the prosthesis from the tympanic membrane at post-ossiculoplasty by finite element method.
  
  
  METHODS
  A finite element model of the human middle ear has been constructed and used as the model of the constructed middle ear at post-ossiculoplasty. Then the fatigue life of the tympanic membrane was calculated under different sound pressure level using this model.
  
  
  RESULTS
  The tympanic membrane would not be extruded under normal sound pressure level. The sound pressure level which caused the tympanic membrane to crack in less than 3 years was higher than 145.17 dB (362.5 Pa).
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shanghai Zhongshan Hospital affiliated to Fudan University , Shanghai , PR China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhou
authors.affiliation: b Department of State Key Laboratory of Ocean Engineering , Shanghai Jiao Tong University , Shanghai , PR China.
authors.forename: Miaolin
authors.initials: M
authors.lastname: Feng
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shanghai Zhongshan Hospital affiliated to Fudan University , Shanghai , PR China.
authors.forename: Xinsheng
authors.initials: X
authors.lastname: Huang
authors.affiliation: c Department of Clinical Science, Intervention and Technology , Karolinska Institutet , Stockholm , Sweden.|d Department of Neurotology and Audiology , Karolinska University Hospital , Stockholm , Sweden.|e Department of Otolaryngology , Karolinska University Hospital , Stockholm , Sweden.
authors.forename: Maoli
authors.initials: M
authors.lastname: Duan
mesh_terms: D020342:Finite Element Analysis; D006801:Humans; D008954:Models, Biological; D013506:Otologic Surgical Procedures; D013314:Stress, Mechanical; D014432:Tympanic Membrane / Q000502:physiology*; D016474:Weight-Bearing
keywords: Ossiculoplasty; fatigue; finite element analysis; stress