title: A MnO2nanosheet-assisted GSH detection platform using an iridium(iii) complex as a switch-on luminescent probe.
abstract: A rapid and sensitive detection platform for GSH has been constructed by combining a MnO2nanosheet with a luminescent iridium(iii) complex [Ir(Cl-phq)2(Cl-phen)]+. The MnO2nanosheet was prepared by using a facile one-step approach and was characterized by TEM. The luminescence intensity of the detection platform responded linearly with the GSH concentration from 1 to 200 μM (R2= 0.9951), and the detection limit for GSH was 0.13 μM. More importantly, practical application of the detection platform for visualizing the intracellular GSH distribution in living zebrafish has also been demonstrated.
authors.affiliation: Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. edmondma@hkbu.edu.hk.
authors.forename: Zhen-Zhen
authors.initials: ZZ
authors.lastname: Dong
authors.affiliation: Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. edmondma@hkbu.edu.hk and College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, China.
authors.forename: Lihua
authors.initials: L
authors.lastname: Lu
authors.affiliation: Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. edmondma@hkbu.edu.hk.
authors.forename: Chung-Nga
authors.initials: CN
authors.lastname: Ko
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. duncanleung@umac.mo.
authors.forename: Chao
authors.initials: C
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. duncanleung@umac.mo.
authors.forename: Shengnan
authors.initials: S
authors.lastname: Li
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. duncanleung@umac.mo.
authors.forename: Ming-Yuen
authors.initials: MY
authors.lastname: Lee
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. duncanleung@umac.mo.
authors.forename: Chung-Hang
authors.initials: CH
authors.lastname: Leung
authors.affiliation: Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. edmondma@hkbu.edu.hk.
authors.forename: Dik-Lung
authors.identifier: http://orcid.org/0000-0002-1458-6263
authors.initials: DL
authors.lastname: Ma