title: Serum anti-Müllerian hormone levels decrease after endometriosis surgery.
abstract: The purpose of this study was to evaluate and compare the post-operative decline in serum AMH levels in patients with endometriosis and other benign cysts. This study also attempts to clarify the factors of endometriosis that may influence the AMH level. A total of 75 were recruited prospectively between 2011 and 2012. Fifty-nine patients had endometriosis, while the other 16 had another kind of benign ovarian cyst. In the endometriosis group, the AMH level decreased significantly from pre- to postoperatively (4.3 ± 0.4 vs. 2.8 ± 0.2, p<.001). This significant decrement in AMH levels was present in the endometriosis group regardless of multiplicity (p=.028 vs. p<.001) and bilaterality (p=.003 vs. p<.001). The stage III-IV endometriosis group also demonstrated a significant decrease (p<.001). Laparoscopic ovarian cystectomy in patients with endometriosis may cause a decrease in serum AMH levels. We suggest that preoperative and postoperative AMH levels should be evaluated in reproductive-aged women with endometriosis for their future fertility.
authors.affiliation: a Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Centre, Dankook University College of Medicine , Seoul , South Korea.
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: a Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Centre, Dankook University College of Medicine , Seoul , South Korea.
authors.forename: Sun-Wha
authors.initials: SW
authors.lastname: Cha
authors.affiliation: a Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Centre, Dankook University College of Medicine , Seoul , South Korea.
authors.forename: Hye-Ok
authors.initials: HO
authors.lastname: Kim
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D004715:Endometriosis / Q000097:blood* / Q000145:classification / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D010048:Ovarian Cysts / Q000097:blood; D065851:Ovarian Reserve; D011184:Postoperative Period; D011446:Prospective Studies; D018709:Statistics, Nonparametric
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Anti-Müllerian hormone; cyst; endometriosis; laparoscopy; ovarian reserve