title: Short-Term Changes in Cardiovascular Hemodynamics in Response to Bariatric Surgery and Weight Loss Using the Nexfin® Non-invasive Continuous Monitoring Device: a Pilot Study.
abstract: Compared to healthy individuals, obese have significantly higher systolic and diastolic blood pressure, mean arterial pressure, heart rate, and cardiac output. The aim of this study was to evaluate cardiovascular hemodynamic changes before and 3 months after bariatric surgery.
  
  
  
  Patients scheduled for bariatric surgery between the 29th of September 2016 and 24th of March 2016 were included and compared with 24 healthy individuals. Hemodynamic measurements were performed preoperatively and 3 months after surgery, using the Nexfin® non-invasive continuous hemodynamic monitoring device (Edwards Lifesciences/BMEYE B.V., Amsterdam, the Netherlands).
  
  
  
  Eighty subjects were included in this study, respectively, 56 obese patients scheduled for bariatric surgery and 24 healthy individuals. Baseline hemodynamic measurements showed significant differences in cardiac output (6.5 ± 1.6 versus 5.7 ± 1.6 l/min, p = 0.046), mean arterial pressure (107 ± 19 versus 89 ± 11 mmHg, p = 0.001), systolic (134 ± 24 versus 116 ± 18 mmHg, p = 0.001) and diastolic blood pressure (89 ± 17 versus 74 ± 10 mmHg, p = 0.001), and heart rate (87 ± 12 versus 76 ± 14 bpm, p = 0.02) between obese and healthy subjects. Three months after surgery, significant changes occurred in mean arterial pressure (89 ± 17 mmHg, p = 0.001), systolic (117 ± 24 mmHg, p = 0.001) and diastolic blood pressure (71 ± 15 mmHg, p = 0.001), stroke volume (82.2 ± 22.4 ml, p = 0.03), and heart rate (79 ± 17 bpm, p = 0.02) CONCLUSIONS: Three months after bariatric surgery, significant improvements occur in hemodynamic variables except cardiac output and cardiac index, in the patient group.
authors.affiliation: Department of Surgery, Catharina Hospital, Michelangelolaan 2, P.O. Box 1350, 5602, ZA, Eindhoven, The Netherlands. Sjaakpwls@gmail.com.|Department of Epidemiology, CAPHRI Research School, Maastricht University, Maastricht, The Netherlands. Sjaakpwls@gmail.com.
authors.forename: Sjaak
authors.initials: S
authors.lastname: Pouwels
authors.affiliation: Department of Anaesthesiology, Intensive Care and Pain Medicine, Catharina Hospital, Eindhoven, The Netherlands.
authors.forename: Bianca
authors.initials: B
authors.lastname: Lascaris
authors.affiliation: Department of Surgery, Catharina Hospital, Michelangelolaan 2, P.O. Box 1350, 5602, ZA, Eindhoven, The Netherlands.
authors.forename: Simon W
authors.initials: SW
authors.lastname: Nienhuijs
authors.affiliation: Department of Anaesthesiology, Intensive Care and Pain Medicine, Catharina Hospital, Eindhoven, The Netherlands.
authors.forename: Arthur R
authors.initials: AR
authors.lastname: Bouwman
authors.affiliation: Department of Anaesthesiology, Intensive Care and Pain Medicine, Catharina Hospital, Eindhoven, The Netherlands.
authors.forename: Marc P
authors.initials: MP
authors.lastname: Buise
mesh_terms: D000328:Adult; D062186:Arterial Pressure / Q000502:physiology; D050110:Bariatric Surgery / Q000379:methods; D001794:Blood Pressure / Q000502:physiology; D002302:Cardiac Output / Q000502:physiology; D015897:Comorbidity; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000295:instrumentation; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D009767:Obesity, Morbid / Q000503:physiopathology* / Q000601:surgery; D010865:Pilot Projects; D011300:Preoperative Care / Q000295:instrumentation; D015431:Weight Loss / Q000502:physiology*
keywords: Bariatric surgery; Blood pressure monitoring; Cardiac physiology; Hemodynamics; Nexfin