title: The Bruton tyrosine kinase inhibitor ibrutinib abrogates triggering receptor on myeloid cells 1-mediated neutrophil activation.
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Nicole
authors.initials: N
authors.lastname: Stadler
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Astrid
authors.initials: A
authors.lastname: Hasibeder
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Pamela Aranda
authors.initials: PA
authors.lastname: Lopez
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Teschner
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Desuki
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Oliver
authors.initials: O
authors.lastname: Kriege
authors.affiliation: Institute for Cell Biology, Department of Immunology, Eberhardt Karls-University of Tübingen, Germany.
authors.forename: Alexander N R
authors.initials: ANR
authors.lastname: Weber
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.|Associated Hematology Practice, Bad Kreuznach, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Schulz
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Michel
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Heβ
authors.affiliation: Department of Hematology, Medical Oncology & Pneumology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany radsak@uni-mainz.de.
authors.forename: Markus P
authors.initials: MP
authors.lastname: Radsak
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives; D000818:Animals; D015415:Biomarkers; D006801:Humans; D051379:Mice; D018375:Neutrophil Activation / Q000187:drug effects* / Q000235:genetics* / Q000276:immunology; D009504:Neutrophils / Q000187:drug effects* / Q000276:immunology / Q000378:metabolism*; D010880:Piperidines; D047428:Protein Kinase Inhibitors / Q000494:pharmacology*; D011720:Pyrazoles / Q000494:pharmacology*; D011743:Pyrimidines / Q000494:pharmacology*; D016897:Respiratory Burst / Q000187:drug effects / Q000235:genetics / Q000276:immunology; D000073871:Triggering Receptor Expressed on Myeloid Cells-1 / Q000235:genetics* / Q000378:metabolism
chemical_list: D015415:Biomarkers; D010880:Piperidines; D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D011743:Pyrimidines; C408842:TREM1 protein, human; D000073871:Triggering Receptor Expressed on Myeloid Cells-1; C551803:ibrutinib; D000225:Adenine