title: Clinical applications of multi-parametric CMR in myocarditis and systemic inflammatory diseases.
abstract: Cardiac magnetic resonance (CMR) has changed the management of suspected viral myocarditis by providing a 'positive' diagnostic test and has lead to new insights into myocardial involvement in systemic inflammatory conditions. In this review we analyse the use of CMR tissue characterisation techniques across the available studies including T2 weighted imaging, early gadolinium enhancement, late gadolinium enhancement, Lake Louise Criteria, T2 mapping, T1 mapping and extracellular volume assessment. We also discuss the use of multiparametric CMR in acute cardiac transplant rejection and a variety of inflammatory conditions such as sarcoidosis, systemic lupus erythrematous, rheumatoid arthritis and systemic sclerosis.
authors.affiliation: North West Heart Centre, University Hospital of South Manchester, Manchester, UK.|Institute of Cardiovascular Sciences, Faculty of Medical & Human Sciences, University of Manchester, Manchester, M13 9NT, UK.
authors.forename: Jakub
authors.initials: J
authors.lastname: Lagan
authors.affiliation: North West Heart Centre, University Hospital of South Manchester, Manchester, UK.
authors.forename: Matthias
authors.initials: M
authors.lastname: Schmitt
authors.affiliation: North West Heart Centre, University Hospital of South Manchester, Manchester, UK. christopher.miller@manchester.ac.uk.|Institute of Cardiovascular Sciences, Faculty of Medical & Human Sciences, University of Manchester, Manchester, M13 9NT, UK. christopher.miller@manchester.ac.uk.
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Miller
mesh_terms: D064591:Allografts; D003287:Contrast Media / Q000008:administration & dosage; D006084:Graft Rejection / Q000000981:diagnostic imaging / Q000209:etiology; D006331:Heart Diseases / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D016027:Heart Transplantation / Q000009:adverse effects; D006801:Humans; D007249:Inflammation / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009205:Myocarditis / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000821:virology; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors
chemical_list: D003287:Contrast Media
keywords: Acute cardiac; Allograft rejection; Cardiac magnetic resonance; Extracellular volume assessment; Late gadolinium enhancement; Myocarditis; Rheumatoid arthritis; Sarcoidosis; Systemic lupus erythematosus; Systemic sclerosis; T1 mapping; T2 mapping