title: Hydroaminoalkylation of Allylsilanes and a One-Pot Procedure for the Synthesis of 1,5-Benzoazasilepines.
abstract: Allylsilanes undergo highly regioselective intermolecular alkene hydroaminoalkylation with secondary amines in the presence of a titanium mono(formamidinate) catalyst. Corresponding reactions of a suitable allyl(2-bromophenyl)silane which exclusively deliver the branched hydroaminoalkylation products combined with a subsequent Buchwald-Hartwig amination result in the development of an elegant one-pot procedure for the synthesis of literature-unknown silicon analogues of 1,5-benzodiazepines, the so-called 1,5-benzoazasilepines.
authors.affiliation: Institut für Chemie, Universität Oldenburg, Carl-von-Ossietzky-Straße 9-11, 26111, Oldenburg, Germany.
authors.forename: Lars H
authors.initials: LH
authors.lastname: Lühning
authors.affiliation: Institut für Chemie, Universität Oldenburg, Carl-von-Ossietzky-Straße 9-11, 26111, Oldenburg, Germany.
authors.forename: Julia
authors.initials: J
authors.lastname: Strehl
authors.affiliation: Institut für Chemie, Universität Oldenburg, Carl-von-Ossietzky-Straße 9-11, 26111, Oldenburg, Germany.
authors.forename: Marc
authors.initials: M
authors.lastname: Schmidtmann
authors.affiliation: Institut für Chemie, Universität Oldenburg, Carl-von-Ossietzky-Straße 9-11, 26111, Oldenburg, Germany.
authors.forename: Sven
authors.initials: S
authors.lastname: Doye
keywords: amination; amines; palladium; silanes; titanium