title: Reference values for kaolin-activated thromboelastography in volunteers of Anhui Province in China.
abstract: BACKGROUND
  The assessment of the coagulation status using thromboelastography (TEG) in Chinese population has less been reported. This study aimed to establish reliable reference values for kaolin-activated TEG in Chinese volunteers.
  
  
  METHODS
  A total of 1681 Chinese adult individuals were recruited for this study. The reference individuals were stratified by gender and age, and the TEG values were measured on the basis of strict quality control. The 95% reference values were determined using nonparametric statistical methods.
  
  
  RESULTS
  The sex-related 95% reference values were reaction time (R):4.2-8.7 minutes; clotting time (K): 1.2-3.2 minutes; alpha angle (α): 47.0-72.3 degree; maximum amplitude (MA): 49.1-70.5 mm for males, and R: 3.7-9.0 minutes; K: 1.0-3.2 minutes; α: 48.4-74.4 degree; MA: 46.8-72.4 mm for females. Also, the TEG parameters indicated a relatively more hypercoagulable profile in both female and elder groups.
  
  
  CONCLUSIONS
  This study established the reference values for kaolin-activated TEG in the target Chinese population, which might provide a reference for both clinical and laboratory studies.
authors.affiliation: Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.|Department of Blood Transfusion, The Second Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: Jun-Bo
authors.initials: JB
authors.lastname: Sun
authors.affiliation: Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: Mao-Hong
authors.initials: MH
authors.lastname: Bian
authors.affiliation: Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhong
authors.affiliation: Department of Blood Transfusion, The Second Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: Ying-Yu
authors.initials: YY
authors.lastname: Lu
authors.affiliation: Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: Bang-Qiang
authors.initials: BQ
authors.lastname: Zhu
authors.affiliation: Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: Hui-Qin
authors.initials: HQ
authors.lastname: Wen
authors.affiliation: Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: Hai-Liang
authors.initials: HL
authors.lastname: Hu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001777:Blood Coagulation / Q000187:drug effects*; D002681:China; D005260:Female; D006801:Humans; D007616:Kaolin / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013916:Thrombelastography / Q000379:methods / Q000592:standards / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D007616:Kaolin
keywords: Chinese; coagulation; reference values; thromboelastography