title: Distribution and Drug Susceptibility ofCandidaspp. Associated With Female Genital Tract Infection, Chongqing, China.
abstract: BACKGROUND
  Vulvovaginal candidiasis is defined as vulvovaginitis associated with vaginal carriage ofCandidaspp. and is a common problem with a high rate of morbidity.
  
  
  OBJECTIVE
  To investigate the distribution ofCandidaspp. and evaluate the corresponding antifungal susceptibility in women with genital tract infection in Chongqing, southwestern China.
  
  
  METHODS
  Samples (n = 2.129) were obtained from female patients with symptoms of genital tract infection.Candidaspp. were isolated from the specimens and were identified using a coloration medium and the VITEK 2 Compact automatic microbial identification system. Antifungal susceptibility testing was performed using the ATB FUNGUS drug susceptibility testing system.
  
  
  RESULTS
  From 2,129 samples, 478 (22.45%) isolates ofCandidawere isolated, of which 395 (82.64%) wereCandida albicans, 39 (8.16%) wereC. glabrata, 21 (4.39%) wereC. tropicalis, 9 (1.88%) wereC. parapsilosis,and 14 (2.93%) were otherCandidaspp. The resistance ofC. albicans,C. glabrata,andC. tropicalisto 5 antifungal drugs (amphotericin B, voriconazole, fluconazole, 5-fluorocytosine, and itraconazole) ranged from 0.5% to 6.4%, 0% to 7.7%, and 0% to 9.6%, respectively.
  
  
  CONCLUSIONS
  Candida albicanswas the major pathogen associated with candidiasis of the female genital tract in patients in Chongqing. The results of the antifungal sensitivity of the isolates suggest that it is important for clinicians to administer appropriate antifungals for the treatment ofCandidaspp. infections.
authors.affiliation: Department of Obstetrics and Gynecology, Second Affiliate Hospital, Chongqing University of Medical Sciences, Chongqing, China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Luo
authors.affiliation: Department of Obstetrics and Gynecology, Second Affiliate Hospital, Chongqing University of Medical Sciences, Chongqing, China.
authors.forename: Xiaojing
authors.initials: X
authors.lastname: Dong
authors.affiliation: Department of Obstetrics and Gynecology, Second Affiliate Hospital, Chongqing University of Medical Sciences, Chongqing, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Pen
keywords: Antifungals; Candida spp; Genital Tract Infection