title: Pd/Cu-Catalyzed aerobic oxidative aromatic C-H bond activation/N-dealkylative carbonylation towards the synthesis of phenanthridinones.
abstract: It is important to achieve diverse functionalization of tertiary anilines due to their importance in biological molecules, pharmaceutical, functional materials, and ligands. A straightforward Pd/Cu-catalyzed oxidative C-H bond activation/N-dealkylative carbonylation of tertiary [1,1'-biphenyl]-2-anilines towards the synthesis of various biologically important phenanthridin-6(5H)-ones has been developed. A wide range of functional groups are well tolerated in this transformation. Moreover, O2is utilized as the terminal oxidant to promote the oxidative carbonylation process.
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan 430072, P. R. China. aiwenlei@whu.edu.cn.
authors.forename: Renyi
authors.initials: R
authors.lastname: Shi
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan 430072, P. R. China. aiwenlei@whu.edu.cn.
authors.forename: Huiying
authors.initials: H
authors.lastname: Niu
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan 430072, P. R. China. aiwenlei@whu.edu.cn.
authors.forename: Lijun
authors.initials: L
authors.lastname: Lu
authors.affiliation: College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan 430072, P. R. China. aiwenlei@whu.edu.cn and State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China.
authors.forename: Aiwen
authors.identifier: http://orcid.org/0000-0001-8417-3061
authors.initials: A
authors.lastname: Lei