title: How to identify patients at risk of abdominal compartment syndrome after surgical repair of ruptured abdominal aortic aneurysms in the operating room: A pilot study.
abstract: Objectives Abdominal compartment syndrome (ACS) is poorly identified in surgery for ruptured abdominal aortic aneurysm and an early management is crucial. The aim of this study was to validate how many risk factors were needed to predict ACS. Secondary objectives were to assess its prevalence and the 30-day mortality. Methods All patients operated for ruptured abdominal aortic aneurysm during 5 years were included. An independent committee performed a retrospective diagnosis of ACS. Eight criteria were selected from the literature, and corresponded to pre- and intraoperative period: anemia (hemoglobin lower than 10 g/dL), prolonged shock (systolic blood pressure <90 mmHg more than 18 min), preoperative cardiac arrest, obesity (body mass index > 30), massive fluid resuscitation (≥3500 mL per hour for at least 1 h) and transfusions (>10 units packed blood red cell since the beginning of the treatment), severe hypothermia (≤33℃), acidosis (pH < 7.2). Sensitivity and specificity were assessed for each number of criteria. Results Eight patients were ACS+ and 28 ACS-, with three criteria for ACS+ and 1.5 for ACS- ( p = 0.002). Three criteria among the eight selected criteria have the best cutoff for sensitivity and specificity (75% and 82%) with a positive predictive value of 54% and a negative predictive value of 92%. The prevalence of ACS was 17%. The 30-day mortality in ACS+ tended to be higher than in ACS- ( p = 0.108). Conclusion The present results suggest that patients with an ACS seemed to have higher mortality and the threshold of three factors among eight specific factors is enough to predict this.
authors.affiliation: 1 Vascular Surgery Unit, University Hospital of Besançon, Besançon, France.|2 EA 3920, University of Franche-Comté, Besançon, France.
authors.forename: Betty
authors.initials: B
authors.lastname: Leclerc
authors.affiliation: 1 Vascular Surgery Unit, University Hospital of Besançon, Besançon, France.|2 EA 3920, University of Franche-Comté, Besançon, France.
authors.forename: Lucie
authors.initials: L
authors.lastname: Salomon Du Mont
authors.affiliation: 2 EA 3920, University of Franche-Comté, Besançon, France.|3 Department of Anesthesiology and Intensive Care Medicine, University Hospital of Besançon, Besançon, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Besch
authors.affiliation: 1 Vascular Surgery Unit, University Hospital of Besançon, Besançon, France.|2 EA 3920, University of Franche-Comté, Besançon, France.
authors.forename: Simon
authors.initials: S
authors.lastname: Rinckenbach
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D001019:Aortic Rupture / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D019540:Area Under Curve; D042241:Early Diagnosis; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D059325:Intra-Abdominal Hypertension / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009873:Operating Rooms; D010865:Pilot Projects; D011237:Predictive Value of Tests; D015995:Prevalence; D012372:ROC Curve; D015203:Reproducibility of Results; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects* / Q000401:mortality
keywords: Aortic rupture; aortic aneurysm; compartment syndrome; intra-abdominal hypertension