title: [A Case of Pure Squamous Cell Carcinoma of the Breast in an Elderly Woman Diagnosed by Cytology].
abstract: A n 85-year-old woman presented with a mass in the left breast. A3 7mm lobulated mass including enhancement of a cyst of 37mm was detected by sonography. An axillary lymph node had increased to 16 mm. Atypical cells dyed by light green and orange G were identified by fine needle aspiration and cytology. She was diagnosed with left breast cancer(cT2N1M0, Stage II B), histologically suspected to be squamous cell carcinoma. She underwent a left-breast-conserving surgery and axillary lymph node dissection. On pathology, a cyst of 34×30mm was noted. The tumor grew from inside the cyst to the surround- ing tissue and it had a trend for keratinocytes. Lymph node metastases affected 1/11. By immunostaining, the tumor was found to be ER(+), PgR(-), HER2(-), CK5/6(+), p40(+), mammaglobin(-), and GCDFP15(-). There was no component of ductal carcinoma. She received radiotherapy to the left breast and tamoxifen as an adjuvant therapy. Squamous cell carcinoma of the breast is rare. We encountered a case of pure squamous cell carcinoma of the breast in an elderly woman. We report this case with a discussion of the relevant literature.
authors.affiliation: Dept. of Surgery, Kansai Rosai Hospital.
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Sato
authors.forename: Junichi
authors.initials: J
authors.lastname: Inatome
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Okishiro
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Oneda
authors.forename: Tomo
authors.initials: T
authors.lastname: Ishida
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Morimoto
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Kuwahara
authors.forename: Hiroki
authors.initials: H
authors.lastname: Kusama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Naito
authors.forename: Kohei
authors.initials: K
authors.lastname: Murakami
authors.forename: Yoshiteru
authors.initials: Y
authors.lastname: Katsura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ohmura
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kagawa
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takeno
authors.forename: Chiyomi
authors.initials: C
authors.lastname: Egawa
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takeda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kato
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Tamura
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Takatsuka
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Goto
authors.forename: Teruaki
authors.initials: T
authors.lastname: Nagano
authors.forename: Shinichi
authors.initials: S
authors.lastname: Nakatsuka
mesh_terms: D000369:Aged, 80 and over; D001365:Axilla; D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D015412:Mastectomy, Segmental