title: Thyroid Stimulating Hormone Receptor.
abstract: Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by several oncogenes. This article will provide a brief review of TSHR and related diseases.
authors.affiliation: Hacettepe University Faculty of Medicine, Department of Nuclear Medicine, Ankara, Turkey, Phone: +90 536 213 03 41, E-mail: muratmtx@yahoo.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Tuncel