title: The Effect of Depression in Chronic Hemodialysis Patients on Inpatient Hospitalization Outcomes.
abstract: OBJECTIVE
  Depression is common in patients with end-stage renal disease (ESRD) on hemodialysis (HD). Although, depression is associated with mortality, the effect of depression on in-hospital outcomes has not been studied as yet.
  
  
  METHODS
  We analyzed the National Inpatient Sample for trends and outcomes of hospitalizations with depression in patients with ESRD.
  
  
  RESULTS
  The proportion of ESRD hospitalizations with depression doubled from 2005 to 2013 (5.01-11.78%). Hospitalized patients on HD with depression were younger (60.47 vs. 62.70 years, p < 0.0001), female (56.93 vs. 47.81%, p < 0.0001), white (44.92 vs. 34.01%, p < 0.0001), and had higher proportion of comorbidities. However, there was a statistically significant lower risk of mortality in HD patients within the top 5 reasons for admissions.
  
  
  CONCLUSIONS
  There were significant differences in demographics and comorbidities for hospitalized HD patients with depression. Depression was associated with an increased rate of adverse effects in discharged patients, and decreased in-hospital mortality.
authors.affiliation: Department of Nephrology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.
authors.forename: Lili
authors.initials: L
authors.lastname: Chan
authors.forename: Sri Lekha
authors.initials: SL
authors.lastname: Tummalapalli
authors.forename: Rocco
authors.initials: R
authors.lastname: Ferrandino
authors.forename: Priti
authors.initials: P
authors.lastname: Poojary
authors.forename: Aparna
authors.initials: A
authors.lastname: Saha
authors.forename: Kinsuk
authors.initials: K
authors.lastname: Chauhan
authors.forename: Girish N
authors.initials: GN
authors.lastname: Nadkarni
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003863:Depression / Q000401:mortality / Q000503:physiopathology*; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects* / Q000401:mortality / Q000523:psychology; D051436:Renal Insufficiency, Chronic / Q000401:mortality / Q000523:psychology*; D012307:Risk Factors; D055815:Young Adult