title: Reproductive Outcome of Transcervical Uterine Incision in Unicornuate Uterus.
abstract: BACKGROUND
  The pregnancy outcome of the unicornuate uterus is associated with an increased risk of miscarriage, cervical incompetence, and a number of obstetric complications. However, at present, there is no accepted treatment method for women with unicornuate uterus, other than expectant measures. The aim of this study was to evaluate the reproductive outcome of transcervical uterine incision (TCUI) in patients with unicornuate uterus.
  
  
  METHODS
  Thirty-three patients with unicornuate uterus presented to our tertiary center for infertility or miscarriage. All 33 patients underwent TCUI and were followed up for 10-52 months. The pregnancy outcomes ( first-trimester miscarriage, second-trimester miscarriage, preterm, term, intrauterine death, ongoing pregnancy, and live birth) before and after TCUI were compared by t- test.
  
  
  RESULTS
  Among 31 patients who attempted to conceive after TCUI, twenty conceived including one termination of pregnancy, one second-trimester miscarriage, one ectopic pregnancy, five preterm deliveries, 11 term delivery, and one ongoing pregnancy. There were 16 live births in total. There was significant reduction in the first-trimester miscarriage rate (t = 4.890; P< 0.001), increase in term delivery (t = -3.288; P = 0.002), and live birth rates (t = -4.073; P< 0.001) after TCUI.
  
  
  CONCLUSIONS
  TCUI appeared to improve the pregnancy outcome in women with unicornuate uterus presenting with infertility or miscarriage.
authors.affiliation: Hysteroscopic Center, Fu Xing Hospital, Capital Medical University, Beijing 100038, China.
authors.forename: En-Lan
authors.initials: EL
authors.lastname: Xia
authors.affiliation: Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Hong Kong 999077, China.
authors.forename: Tin-Chiu
authors.initials: TC
authors.lastname: Li
authors.affiliation: Department of Obstetrics and Gynaecology, United Christian Hospital, Hong Kong 999077, China.
authors.forename: Sze-Ngar Sylvia
authors.initials: SS
authors.lastname: Choi
authors.affiliation: Hysteroscopic Center, Fu Xing Hospital, Capital Medical University, Beijing 100038, China.
authors.forename: Qiao-Yun
authors.initials: QY
authors.lastname: Zhou
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*; D011256:Pregnancy Outcome; D014564:Urogenital Abnormalities / Q000601:surgery*; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery*