title: Chemical Composition andIn VitroAntioxidant, Cytotoxic, Antimicrobial, and Larvicidal Activities of the Essential Oil ofMentha piperitaL. (Lamiaceae).
abstract: The essential oil was obtained by hydrodistillation and the identification and quantification of components were achieved with the use of GC-MS analysis. The antioxidant activity was evaluated by the method of sequestration of DPPH. Essential oils were used for study the cytotoxic front larvae ofArtemia salina. In the evaluation of the antimicrobial activity of essential oils, we employed the disk-diffusion method. The potential larvicide in mosquito larvae of the third stage of development ofAedes aegyptito different concentrations of essential oils was evaluated. The major compounds found in the essential oils ofM. piperitawere linalool (51.8%) and epoxyocimene (19.3%). The percentage of antioxidant activity was 79.9 ± 1.6%. The essential oil showed LC50= 414.6μg/mL front ofA. salineand is considered highly toxic. It shows sensitivity and halos significant inhibition againstE. coli. The essential possessed partial larvicidal efficiency againstA. aegypti.
authors.affiliation: Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil.
authors.forename: Ryan
authors.initials: R
authors.lastname: da Silva Ramos
authors.affiliation: Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil.
authors.forename: Alex Bruno Lobato
authors.initials: AB
authors.lastname: Rodrigues
authors.affiliation: Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil.
authors.forename: Ana Luzia Ferreira
authors.initials: AL
authors.lastname: Farias
authors.affiliation: Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil.
authors.forename: Ranggel Carvalho
authors.initials: RC
authors.lastname: Simões
authors.affiliation: Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil.
authors.forename: Mayara Tânia
authors.initials: MT
authors.lastname: Pinheiro
authors.affiliation: Laboratory of Arthropoda, Federal University of Amapá, Rodovia Juscelino Kubitschek, Km 02, Jardim Marco Zero, Macapá, AP, Brazil.
authors.forename: Ricardo Marcelo Dos Anjos
authors.initials: RM
authors.lastname: Ferreira
authors.affiliation: Laboratory of Arthropoda, Federal University of Amapá, Rodovia Juscelino Kubitschek, Km 02, Jardim Marco Zero, Macapá, AP, Brazil.
authors.forename: Ledayane Mayana
authors.initials: LM
authors.lastname: Costa Barbosa
authors.affiliation: Laboratory of Arthropoda, Federal University of Amapá, Rodovia Juscelino Kubitschek, Km 02, Jardim Marco Zero, Macapá, AP, Brazil.
authors.forename: Raimundo Nonato
authors.initials: RN
authors.lastname: Picanço Souto
authors.affiliation: Department of Chemistry, Federal University of São Carlos, Washington Luis Highway, Km 235, SP-310, 13565-905 São Carlos, SP, Brazil.
authors.forename: João Batista
authors.initials: JB
authors.lastname: Fernandes
authors.affiliation: Laboratory of Chemistry, Federal University of Pará, Rua Augusto Corrêa, 01-Setor Básico, 66075-110 Belém, PA, Brazil.
authors.forename: Lourivaldo da Silva
authors.identifier: 0000-0001-6698-1743
authors.initials: LD
authors.lastname: Santos
authors.affiliation: Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil.
authors.forename: Sheylla Susan Moreira da Silva
authors.identifier: 0000-0002-7687-8288
authors.initials: SS
authors.lastname: de Almeida
mesh_terms: D000330:Aedes; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D001156:Artemia / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007306:Insecticides; D007814:Larva; D036142:Mentha piperita / Q000737:chemistry*; D009822:Oils, Volatile / Q000494:pharmacology*; D010938:Plant Oils / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D007306:Insecticides; D009822:Oils, Volatile; D010938:Plant Oils