title: New strategies for cancer immunotherapy: targeting regulatory T cells.
abstract: The immunosuppressive action of regulatory T (Treg) cells is one mechanism attributed to the limited success of cancer immunotherapies with checkpoint blockers. Two recent studies report distinct transcriptional profiles of tumor-infiltrating Tregcells and expression of specific molecules, suggesting novel strategies to overcome resistance to cancer immunotherapy.
authors.affiliation: Biocenter, Division of Bioinformatics, Medical University of Innsbruck, Innsbruck, 6020, Austria.
authors.forename: Francesca
authors.initials: F
authors.lastname: Finotello
authors.affiliation: Biocenter, Division of Bioinformatics, Medical University of Innsbruck, Innsbruck, 6020, Austria. zlatko.trajanoski@i-med.ac.at.
authors.forename: Zlatko
authors.initials: Z
authors.lastname: Trajanoski
mesh_terms: D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D050378:T-Lymphocytes, Regulatory