title: R&D in Vaccines Targeting Neglected Diseases: An Exploratory Case Study Considering Funding for Preventive Tuberculosis Vaccine Development from 2007 to 2014.
abstract: Based on an exploratory case study regarding the types of institutions funding the research and development to obtain new tuberculosis vaccines, this article intends to provoke discussion regarding the provision of new vaccines targeting neglected disease. Although our findings and discussion are mainly relevant to the case presented here, some aspects are more generally applicable, especially regarding the dynamics of development in vaccines to prevent neglected diseases. Taking into account the dynamics of innovation currently seen at work in the vaccine sector, a highly concentrated market dominated by few multinational pharmaceutical companies, we feel that global PDP models can play an important role throughout the vaccine development cycle. In addition, the authors call attention to issues surrounding the coordination of actors and resources in the research, development, manufacturing, and distribution processes of vaccine products arising from PDP involvement.
authors.affiliation: Gonçalo Moniz Institute, Oswaldo Cruz Foundation Unit in Bahia State, Rio de Janeiro, RJ, Brazil.
authors.forename: Theolis
authors.initials: T
authors.lastname: Costa Barbosa Bessa
authors.affiliation: Institute of Collective Health, Federal University of Bahia, Salvador, BA, Brazil.
authors.forename: Erika
authors.initials: E
authors.lastname: Santos de Aragão
authors.affiliation: Institute of Humanities Arts and Sciences, Federal University of Southern Bahia, Itabuna, BA, Brazil.
authors.forename: Jane Mary
authors.initials: JM
authors.lastname: Medeiros Guimarães
authors.affiliation: Gonçalo Moniz Institute, Oswaldo Cruz Foundation Unit in Bahia State, Rio de Janeiro, RJ, Brazil.
authors.forename: Bethânia
authors.identifier: 0000-0001-8918-2661
authors.initials: B
authors.lastname: de Araújo Almeida
mesh_terms: D002986:Clinical Trials as Topic; D003299:Cooperative Behavior; D006801:Humans; D038622:Internationality; D058069:Neglected Diseases / Q000191:economics / Q000517:prevention & control*; D012106:Research / Q000191:economics; D014376:Tuberculosis / Q000191:economics / Q000276:immunology* / Q000517:prevention & control*; D032581:Tuberculosis Vaccines / Q000191:economics / Q000276:immunology*
chemical_list: D032581:Tuberculosis Vaccines