title: [Diffuse cutaneous leishmaniasis (DCL) and visceral leishmaniasis (VL) concurrent with cancer: Presentation of a case].
abstract: Male of 52 year old with chronic alcoholism and ulcerated lesion on the face and disseminated nodular skin lesions, underwent to biopsy of ulcer edges where was observed a concomitant epidermoid malignancy with Leishmania (L.). Besides others, biopsies of nodule in the periumbilical region, lymph node and bone marrow were assayed, and all biopsies had abundant amastigotes. The amplified Polymerase Chain Reaction (PCR) products from nodule were sequenced and the alignment analysis demonstrated homology with L. mexicana confirming the infection by this parasite. This is considered the first case of visceral and diffuse cutaneous leishmaniasis concurrent with epidermoid cancer in the state of Campeche.
authors.affiliation: Laboratorio de Enfermedades Tropicales, Centro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Campeche, Camp., México.
authors.forename: Selene Del C
authors.initials: SD
authors.lastname: Blum-Domínguez
authors.affiliation: Servicio de Anatomía Patológica, Hospital General de Especialidades Dr. Javier Buenfil Osorio, Campeche, Camp., México.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Martínez-Vázquez
authors.affiliation: Laboratorio de Microbiología, Centro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Campeche, Camp., México.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Núñez-Oreza
authors.affiliation: Departamento de Ecología y Agentes Patógenos, Hospital General Dr. Manuel Gea González, Campeche, Camp., México.
authors.forename: Fernando
authors.initials: F
authors.lastname: Martínez-Hernández
authors.affiliation: Departamento de Ecología y Agentes Patógenos, Hospital General Dr. Manuel Gea González, Campeche, Camp., México.
authors.forename: Guiehdani
authors.initials: G
authors.lastname: Villalobos
authors.affiliation: Laboratorio de Enfermedades Transmitidas por Vectores y Zoonosis, Centro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Campeche, Camp., México.
authors.forename: Paulino
authors.initials: P
authors.lastname: Tamay-Segovia
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications*; D006801:Humans; D016774:Leishmaniasis, Diffuse Cutaneous / Q000150:complications*; D007898:Leishmaniasis, Visceral / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000150:complications*