title: Role of Imaging in the Era of Precision Medicine.
abstract: Precision medicine is an emerging approach for treating medical disorders, which takes into account individual variability in genetic and environmental factors. Preventive or therapeutic interventions can then be directed to those who will benefit most from targeted interventions, thereby maximizing benefits and minimizing costs and complications. Precision medicine is gaining increasing recognition by clinicians, healthcare systems, pharmaceutical companies, patients, and the government. Imaging plays a critical role in precision medicine including screening, early diagnosis, guiding treatment, evaluating response to therapy, and assessing likelihood of disease recurrence. The Association of University Radiologists Radiology Research Alliance Precision Imaging Task Force convened to explore the current and future role of imaging in the era of precision medicine and summarized its finding in this article. We review the increasingly important role of imaging in various oncological and non-oncological disorders. We also highlight the challenges for radiology in the era of precision medicine.
authors.affiliation: Department of Imaging, Dana-Farber Cancer Institute, Boston, Massachusetts; Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
authors.forename: Angela
authors.initials: A
authors.lastname: Giardino
authors.affiliation: Department of Radiology and Imaging, Medical College of Georgia, 1120 15th St, Augusta, GA 30912. Electronic address: riya10.in@gmail.com.
authors.forename: Supriya
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Radiology Resident, University of California San Diego, San Diego, California.
authors.forename: Emmi
authors.initials: E
authors.lastname: Olson
authors.affiliation: Baylor College of Medicine, Houston, Texas.
authors.forename: Karla
authors.initials: K
authors.lastname: Sepulveda
authors.affiliation: Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
authors.forename: Leon
authors.initials: L
authors.lastname: Lenchik
authors.affiliation: Department of Diagnostic Radiology, Weill Cornell Medicine, New York, New York.
authors.forename: Jana
authors.initials: J
authors.lastname: Ivanidze
authors.affiliation: Department of Radiology, University of California San Diego, San Diego, California.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Rakow-Penner
authors.affiliation: Department of Radiology, University of South Florida, Tampa, Florida.
authors.forename: Midhir J
authors.initials: MJ
authors.lastname: Patel
authors.affiliation: Cyclotron and Molecular Imaging Program, Department of Radiology, UT Southwestern Medical Center, Dallas, Texas.
authors.forename: Rathan M
authors.initials: RM
authors.lastname: Subramaniam
authors.affiliation: Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Dhakshinamoorthy
authors.initials: D
authors.lastname: Ganeshan
mesh_terms: D006801:Humans; D008495:Medical Oncology / Q000193:education*; D057285:Precision Medicine / Q000379:methods*; D011871:Radiology / Q000193:education*
keywords: Precision medicine; imaging in oncology; task force