title: Biomanufacturing Seamless Tubular and Hollow Collagen Scaffolds with Unique Design Features and Biomechanical Properties.
abstract: A versatile process to develop designer collagen scaffolds for hollow and tubular tissue engineering applications is presented. This process creates seamless and biomechanically tunable scaffolds ranging from ureter-like microsized tubings to structures with highly customized lumens that resemble intestinal villi, fluid bladders, and alveolar sacs that together with stem cells can potentially be used in preclinical and clinical settings.
authors.affiliation: Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.|Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.|Translational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD, 21231, USA.
authors.forename: Anirudha
authors.initials: A
authors.lastname: Singh
authors.affiliation: Translational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD, 21231, USA.
authors.forename: David
authors.initials: D
authors.lastname: Lee
authors.affiliation: Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
authors.forename: Nikolai
authors.initials: N
authors.lastname: Sopko
authors.affiliation: Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
authors.forename: Hotaka
authors.initials: H
authors.lastname: Matsui
authors.affiliation: Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
authors.forename: Praveena
authors.initials: P
authors.lastname: Sabnekar
authors.affiliation: Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
authors.forename: Xiaopu
authors.initials: X
authors.lastname: Liu
authors.affiliation: Translational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD, 21231, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Elisseeff
authors.affiliation: Department of Urology, Albert Einstein College of Medicine, Bronx, NY, 10467, USA.
authors.forename: Mark P
authors.initials: MP
authors.lastname: Schoenberg
authors.affiliation: Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.|Department of Surgery and Oncology, Johns Hopkins Medical Institutions and Sidney Kimmel Comprehensive Cancer Center (SKCC), Baltimore, MD, 21287, USA.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Pienta
authors.affiliation: Department of Urology, The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.|Department of Surgery and Oncology, Johns Hopkins Medical Institutions and Sidney Kimmel Comprehensive Cancer Center (SKCC), Baltimore, MD, 21287, USA.
authors.forename: Trinity J
authors.initials: TJ
authors.lastname: Bivalacqua
mesh_terms: D001705:Bioprosthesis; D003094:Collagen / Q000737:chemistry*; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism*; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D003094:Collagen
keywords: biomanufacturing; collagen; neo-urinary bladders; neo-urinary conduits; scaffolds