title: Journal of clinical monitoring and computing 2016 end of year summary: monitoring cerebral oxygenation and autoregulation.
abstract: In the perioperative and critical care setting, monitoring of cerebral oxygenation (ScO2) and cerebral autoregulation enjoy increasing popularity in recent years, particularly in patients undergoing cardiac surgery. Monitoring ScO2is based on near infrared spectroscopy, and attempts to early detect cerebral hypoperfusion and thereby prevent cerebral dysfunction and postoperative neurologic complications. Autoregulation of cerebral blood flow provides a steady flow of blood towards the brain despite variations in mean arterial blood pressure (MAP) and cerebral perfusion pressure, and is effective in a MAP range between approximately 50-150 mmHg. This range of intact autoregulation may, however, vary considerably between individuals, and shifts to higher thresholds have been observed in elderly and hypertensive patients. As a consequence, intraoperative hypotension will be poorly tolerated, and might cause ischemic events and postoperative neurological complications. This article summarizes research investigating technologies for the assessment of ScO2and cerebral autoregulation published in the Journal of Clinical Monitoring and Computing in 2016.
authors.affiliation: Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. t.w.l.scheeren@umcg.nl.
authors.forename: Thomas W L
authors.initials: TW
authors.lastname: Scheeren
authors.affiliation: Department of Anesthesiology, Centre of Anesthesiology and Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Saugel
mesh_terms: D062186:Arterial Pressure / Q000502:physiology; D006348:Cardiac Surgical Procedures / Q000379:methods; D002315:Cardiopulmonary Bypass; D002560:Cerebrovascular Circulation / Q000502:physiology; D003422:Critical Care; D006706:Homeostasis; D006801:Humans; D008490:Medical Informatics / Q000379:methods*; D016343:Monitoring, Intraoperative / Q000379:methods; D008991:Monitoring, Physiologic / Q000379:methods*; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000378:metabolism*; D010506:Periodicals as Topic; D059035:Perioperative Period; D019265:Spectroscopy, Near-Infrared
chemical_list: D010100:Oxygen
keywords: Autoregulation; Cerebral blood flow; Cerebral oximetry; Monitoring; Near infrared spectroscopy; Tissue oxygenation