title: N-N bond formation in Ugi processes: from nitric acid to libraries of nitramines.
abstract: The Ugi reaction has drawn considerable attention over the years leading to numerous libraries of heterocycles and various extensions changing the nature of the components of the coupling. We report here the use of nitric acid as carboxylic acids surrogates, displaying the first aminative Ugi-type reaction leading to nitramines.
authors.affiliation: Laboratoire de Synthèse Organique, CNRS, Ecole Polytechnique, ENSTA ParisTech- UMR 7652, Université Paris-Saclay, 828 Bd des Maréchaux, 91128 Palaiseau, France. laurent.elkaim@ensta-paristech.fr and Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale "A. Avogadro", largo Donegani 2, 28100 Novara, Italy. giancesare.tron@uniupo.it.
authors.forename: Valentina
authors.initials: V
authors.lastname: Mercalli
authors.affiliation: Laboratoire de Synthèse Organique, CNRS, Ecole Polytechnique, ENSTA ParisTech- UMR 7652, Université Paris-Saclay, 828 Bd des Maréchaux, 91128 Palaiseau, France. laurent.elkaim@ensta-paristech.fr and Ecole normale supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Département de Chimie, PASTEUR, 24, rue Lhomond, 75005 Paris, France and Sorbonne Universités, UPMC Univ Paris 06, ENS, CNRS, PASTEUR, 75005 Paris, France. Laurence.grimaud@ens.fr.
authors.forename: Aude
authors.initials: A
authors.lastname: Nyadanu
authors.affiliation: Laboratoire de Chimie Moléculaire, UMR 9168, Department of Chemistry, Ecole Polytechnique, CNRS, 91128, Palaiseau Cedex, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Cordier
authors.affiliation: Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale "A. Avogadro", largo Donegani 2, 28100 Novara, Italy. giancesare.tron@uniupo.it.
authors.forename: Gian Cesare
authors.initials: GC
authors.lastname: Tron
authors.affiliation: Ecole normale supérieure, PSL Research University, UPMC Univ Paris 06, CNRS, Département de Chimie, PASTEUR, 24, rue Lhomond, 75005 Paris, France and Sorbonne Universités, UPMC Univ Paris 06, ENS, CNRS, PASTEUR, 75005 Paris, France. Laurence.grimaud@ens.fr.
authors.forename: Laurence
authors.initials: L
authors.lastname: Grimaud
authors.affiliation: Laboratoire de Synthèse Organique, CNRS, Ecole Polytechnique, ENSTA ParisTech- UMR 7652, Université Paris-Saclay, 828 Bd des Maréchaux, 91128 Palaiseau, France. laurent.elkaim@ensta-paristech.fr.
authors.forename: Laurent
authors.identifier: http://orcid.org/0000-0001-5729-8010
authors.initials: L
authors.lastname: El Kaim