title: A Time to Pause and Reflect: When a Patient with Autoimmune Hepatitis Stops Responding to Corticosteroids.
abstract: Drug-induced liver injury (DILI) with features of autoimmunity (AI) is a challenging diagnosis to make particularly due to its apparent corticosteroid responsiveness. We present the case of a 74-year-old woman who presented with a 2-week history of jaundice and fatigue. She was initially diagnosed with autoimmune hepatitis (AIH) based on biochemical and histological characteristics and prompt response with budesonide but a biochemical relapse occurred soon after inadvertent rechallenge with irbesartan, a drug that she had discontinued prior to her presentation but was not initially considered to be a cause of her symptoms.
authors.affiliation: The Canberra Hospital, Garran, ACT, Australia.
authors.forename: Lewis
authors.identifier: 0000-0001-9545-3966
authors.initials: L
authors.lastname: Tsang
authors.affiliation: ACT Health Pathology, Garran, ACT, Australia.
authors.forename: Mitali
authors.initials: M
authors.lastname: Fadia
authors.affiliation: The Canberra Hospital, Garran, ACT, Australia.
authors.forename: Shivakumar
authors.initials: S
authors.lastname: Chitturi