title: PET+MR versus PET/CT in the initial staging of head and neck cancer, using a trimodality PET/CT+MR system.
abstract: OBJECTIVE
  To compare the diagnostic accuracy of PET+MR with PET/CT in the initial staging of head and neck cancer.
  
  
  METHODS
  Contrast-enhanced PET/CT+MR was performed in 27 patients with newly diagnosed head and neck cancer. PET/CT and PET+MR were evaluated separately, and the TNM stage and factors influencing treatment were assessed.
  
  
  RESULTS
  The TNM staging by PET+MR was comparable to PET/CT (T: p=0.331, N: p=0.453, M: p=0.034). The sensitivity/specificity/accuracy of treatment-influencing factors by PET/CT and PET+MR were 0.68/0.99/0.97, and 1.00/1.00/0.99, respectively.
  
  
  CONCLUSIONS
  Whole-body staging with PET+MR yields at least equal diagnostic accuracy as PET/CT in head and neck cancer.
authors.affiliation: Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland; Department of Radiology, Nippon Medical School, Tokyo, Japan. Electronic address: tetsuro.sekine@gmail.com.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Sekine
authors.affiliation: Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Felipe
authors.initials: F
authors.lastname: de Galiza Barbosa
authors.affiliation: Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland; Clinic of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Felix P
authors.initials: FP
authors.lastname: Kuhn
authors.affiliation: Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Irene A
authors.initials: IA
authors.lastname: Burger
authors.affiliation: Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland; Clinic of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Paul
authors.initials: P
authors.lastname: Stolzmann
authors.affiliation: Department of Otorhinolaryngology, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Gerhard F
authors.initials: GF
authors.lastname: Huber
authors.affiliation: Clinic of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Spyros S
authors.initials: SS
authors.lastname: Kollias
authors.affiliation: Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Gustav K
authors.initials: GK
authors.lastname: von Schulthess
authors.affiliation: Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland; Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Patrick
authors.initials: P
authors.lastname: Veit-Haibach
authors.affiliation: Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland.
authors.forename: Martin W
authors.initials: MW
authors.lastname: Huellner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D019788:Fluorodeoxyglucose F18; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D009367:Neoplasm Staging; D000072078:Positron Emission Tomography Computed Tomography; D049268:Positron-Emission Tomography; D011446:Prospective Studies; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: ENT surgery; Head and neck cancer; Oncology; PET/CT; PET/MR