title: Sonogashira cross-coupling reactions of 3,5-dibromo-2,6-dichloropyridine.
abstract: A new method for the chemoselective synthesis of alkynylpyridines from 3,5-dibromo-2,6-dichloropyridine has been developed. Optimized conditions give access to a variety of mono-, di-, tri- and tetraalkynylated pyridines in good yields. Interestingly, the employment of 3,5-dibromo-2,6-dichloropyridine as a starting material led to the opposite regioisomers of dialkynylated pyridines as compared to the application of 2,3,5,6-tetrachloropyridine.
authors.affiliation: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany. peter.langer@uni-rostock.de and Leibniz Institut für Katalyse an der Universität Rostock e.V., Albert-Einstein-Str. 29a, 18059 Rostock, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Reimann
authors.affiliation: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany. peter.langer@uni-rostock.de and Leibniz Institut für Katalyse an der Universität Rostock e.V., Albert-Einstein-Str. 29a, 18059 Rostock, Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Ehlers
authors.affiliation: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany. peter.langer@uni-rostock.de.
authors.forename: Lars
authors.initials: L
authors.lastname: Ohlendorf
authors.affiliation: Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany. peter.langer@uni-rostock.de and Leibniz Institut für Katalyse an der Universität Rostock e.V., Albert-Einstein-Str. 29a, 18059 Rostock, Germany.
authors.forename: Peter
authors.identifier: http://orcid.org/0000-0002-7665-8912
authors.initials: P
authors.lastname: Langer