title: Spectroscopic study of prompt-gamma emission for range verification in proton therapy.
abstract: We present the results of an investigation of the prompt-gamma emission from an interaction of a proton beam with phantom materials. Measurements were conducted with a novel setup allowing the precise selection of the investigated depth in the phantom, featuring three different materials composed of carbon, oxygen and hydrogen. We studied two beam energies of 70.54 and 130.87MeV and two detection angles: 90° and 120°. The results are presented in form of profiles of the prompt-gamma yield as a function of depth. In the analysis we focused on the transitions with the largest cross sections:12C4.44→g.s.and16O6.13→g.s.. We compare the profiles obtained under various irradiation conditions, with emphasis on the shape of the distal fall-off. The results are also compared to calculations including different cross-section models. They are in agreement with the model exploiting published cross-section data, but the comparison with the Talys model shows discrepancies.
authors.affiliation: Physics Institute 3B, RWTH Aachen University, Aachen, Germany. Electronic address: laurent.kelleter@physik.rwth-aachen.de.
authors.forename: Laurent
authors.initials: L
authors.lastname: Kelleter
authors.affiliation: Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków, Poland. Electronic address: aleksandra.wronska@uj.edu.pl.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Wrońska
authors.affiliation: Physics Institute 3B, RWTH Aachen University, Aachen, Germany.
authors.forename: Judith
authors.initials: J
authors.lastname: Besuglow
authors.affiliation: Department of Nuclear Physics and its Applications, Institute of Physics, University of Silesia, Katowice, Poland.
authors.forename: Adam
authors.initials: A
authors.lastname: Konefał
authors.affiliation: Physics Institute 3B, RWTH Aachen University, Aachen, Germany.
authors.forename: Karim
authors.initials: K
authors.lastname: Laihem
authors.affiliation: Physics Institute 3B, RWTH Aachen University, Aachen, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Leidner
authors.affiliation: Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Magiera
authors.affiliation: Heidelberg Ion-Beam Therapy Center, Heidelberg, Germany; Department of Medical Physics, Ludwig-Maximilians-Universität München, Munich, Germany.
authors.forename: Katia
authors.initials: K
authors.lastname: Parodi
authors.affiliation: Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Rusiecka
authors.affiliation: Physics Institute 3B, RWTH Aachen University, Aachen, Germany.
authors.forename: Achim
authors.initials: A
authors.lastname: Stahl
authors.affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität München, Munich, Germany; Department of Radiation Oncology, Heidelberg University Clinic, Heidelberg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Tessonnier
mesh_terms: D005720:Gamma Rays / Q000627:therapeutic use*; D019047:Phantoms, Imaging; D061766:Proton Therapy / Q000295:instrumentation / Q000379:methods*; D013057:Spectrum Analysis
keywords: Prompt-gamma imaging; Proton therapy; Range verification