title: Acute liver failure: An up-to-date approach.
abstract: Acute liver failure is a rare but potentially devastating disease. Throughout the last few decades, acute liver failure outcomes have been improving in the context of the optimized overall management. This positive trend has been associated with the earlier recognition of this condition, the improvement of the intensive care unit management, and the developments in emergent liver transplantation. Accordingly, we aimed to review the current diagnostic and therapeutic approach to this syndrome, especially in the intensive care unit setting.
authors.affiliation: Intensive Care Unit, Curry Cabral Hospital, Central Lisbon Hospital Center, Lisbon, Portugal. Electronic address: filipe_sousacardoso@hotmail.com.
authors.forename: Filipe S
authors.initials: FS
authors.lastname: Cardoso
authors.affiliation: Intensive Care Unit, Curry Cabral Hospital, Central Lisbon Hospital Center, Lisbon, Portugal.
authors.forename: Paulo
authors.initials: P
authors.lastname: Marcelino
authors.affiliation: Intensive Care Unit, Curry Cabral Hospital, Central Lisbon Hospital Center, Lisbon, Portugal.
authors.forename: Luís
authors.initials: L
authors.lastname: Bagulho
authors.affiliation: Divisions of Gastroenterology (Liver Unit) and Critical Care, University of Alberta Hospital, Edmonton, Canada.
authors.forename: Constantine J
authors.initials: CJ
authors.lastname: Karvellas
mesh_terms: D003422:Critical Care / Q000639:trends*; D006801:Humans; D007362:Intensive Care Units; D017114:Liver Failure, Acute / Q000628:therapy*; D016031:Liver Transplantation; D012017:Referral and Consultation
keywords: Critical care; Hepatitis; Liver failure