title: Divergent Photocyclization/1,4-Sigmatropic Rearrangements for the Synthesis of Sesquiterpenoid Derivatives.
abstract: Combined experimental and computational efforts have demonstrated the utility of divergent photocyclization/1,4-sigmatropic rearrangement reactions for developing a general strategy toward the synthesis of cubebane-, spiroaxane-, and guaiane-type sesquiterpenes and related analogues. The configuration of the bridgehead substituent, the choice of solvent, and the wavelength of irradiation all impact diastereoselectivity in this tandem reaction process.
authors.affiliation: Department of Chemistry, University of Calgary , 2500 University Drive NW, Calgary, Alberta Canada T2N 1N4.
authors.forename: Evgueni
authors.initials: E
authors.lastname: Gorobets
authors.affiliation: Department of Chemistry, University of Calgary , 2500 University Drive NW, Calgary, Alberta Canada T2N 1N4.
authors.forename: Norman E
authors.initials: NE
authors.lastname: Wong
authors.affiliation: Chemistry Research Laboratory, Oxford University , Mansfield Road, Oxford OX1 3TA, U.K.
authors.forename: Robert S
authors.identifier: 0000-0002-0104-4166
authors.initials: RS
authors.lastname: Paton
authors.affiliation: Department of Chemistry, University of Calgary , 2500 University Drive NW, Calgary, Alberta Canada T2N 1N4.
authors.forename: Darren J
authors.identifier: 0000-0002-5945-6921
authors.initials: DJ
authors.lastname: Derksen