title: Algorithms for the treatment of motor problems in Parkinson's disease.
abstract: Several different strategies are effective for medical treatment of motor problems in Parkinson's disease (PD). Many guidelines and evidence-based reviews are available, but there is no documentation or consensus in favor of just one treatment strategy. This review presents two algorithms that may be helpful when deciding how to treat a PD patient at various stages of the disease. The first algorithm suggests one way to treat PD from the first onset of motor symptoms. It is largely based on treatment recommendations from the Scandinavian countries and Germany. The other algorithm is meant as assistance for choosing among the different device-aided treatments for advanced PD. There is not sufficient comparative data to recommend one particular line of treatment, neither in early PD nor in advanced disease with motor complications. Individualized treatment is needed for each patient. The current algorithms only represent an alternative for aiding treatment decisions.
authors.affiliation: Department of Neurology, Oslo University Hospital and University of Oslo, Oslo, Norway.
authors.forename: E
authors.identifier: http://orcid.org/0000-0002-3328-5263
authors.initials: E
authors.lastname: Dietrichs
authors.affiliation: Department of Neurology, Skåne University Hospital, University of Lund, Lund, Sweden.|Department of Neurology, Klinikum-Bremerhaven, Bremerhaven, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Odin
mesh_terms: D000465:Algorithms; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D002230:Carbidopa / Q000627:therapeutic use*; D032921:Consensus; D046690:Deep Brain Stimulation; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa; D002230:Carbidopa
keywords: Parkinson's disease; apomorphine; deep brain stimulation; levodopa-carbidopa intestinal gel; motor complications; treatment