title: The Role of Probiotic in Reducing Hepatic Inflammation Among NAFLD Patients: an Evidence-based Case Report.
abstract: OBJECTIVE
  to know the effectiveness of probiotic in reducing hepatic inflammation among non-alcoholic fatty liver disease (NAFLD) patients.
  
  
  METHODS
  we performed literature searching regarding the potential role of probiotic in reducing hepatic inflammation among NAFLD patients.
  
  
  RESULTS
  six articles were finally critically appraised. All six studies had good validity and importance. These studies unanimously reported that probiotic is useful in reducing hepatic inflammation, and liver fat content. However, further evidence is needed to show whether or not probiotic is beneficial reducing cirrhosis progression and liver-related mortality.
  
  
  CONCLUSIONS
  probiotic owns robust potential to treat NAFLD. Probiotic reduce hepatic inflammation, as shown by the reduction of liver aminotransferase, and inflammatory markers. Based on this evidence based report, probiotic is a promising adjunct therapy for NAFLD.
authors.affiliation: Departement of Internal Medicine, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia. alvin.nursalim@yahoo.com.
authors.forename: Alvin
authors.initials: A
authors.lastname: Nursalim
authors.forename: Ummi Ulfah
authors.initials: UU
authors.lastname: Madina
authors.forename: Cosmas Rinaldi A
authors.initials: CR
authors.lastname: Lesmana
mesh_terms: D003952:Diagnostic Imaging; D019317:Evidence-Based Medicine; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000188:drug therapy; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease / Q000175:diagnosis* / Q000188:drug therapy*; D019936:Probiotics / Q000627:therapeutic use*
keywords: NAFLD; inflammation; non-alcoholic fatty liver disease; probiotic