title: [A Case of Surgical Resection for Liver Metastasis of Gastric Cancer Treated with Neoadjuvant Chemotherapy].
abstract: The patient was a 73-year-old man. Upper gastrointestinal endoscopy revealed a type 3 tumor in the antrum of the stomach. Preoperative CT imaging showed multiple liver metastases(S2, S3, S4, S6, S7). We administered 2 courses of chemotherapy( XP therapy)for the unresectable gastric cancer; the impact of the neoadjuvant therapy was PR. We performed distal gastrectomy and D2 dissection. After gastric resection, we administered an additional 3 courses of XP therapy. Unfortunately, new lesions of liver metastases were recurrent at S5 and S8. The patient was treated with 3 courses of S-1 chemotherapy. However, abdominal CT and EOB-MRI revealed significant tumor growth despite S-1 therapy. We performed S5 sub-segment resection and S8 partial resection due to the absence of new lesions. Histopathological findings revealed that the well-differentiated adenocarcinoma had metastasized to the liver, with Grade 1a tumor destruction. Two years after the initial gastrectomy, no recurrence of gastric cancer was observed.
authors.affiliation: Dept. of Surgery, Osaka Police Hospital.
authors.forename: Soichiro
authors.initials: S
authors.lastname: Mori
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tanemura
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kishi
authors.forename: Mitsuyoshi
authors.initials: M
authors.lastname: Tei
authors.forename: Toru
authors.initials: T
authors.lastname: Masuzawa
authors.forename: Yozo
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Masahisa
authors.initials: M
authors.lastname: Otsuka
authors.forename: Kenta
authors.initials: K
authors.lastname: Furukawa
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sakano
authors.forename: Kazunori
authors.initials: K
authors.lastname: Mori
authors.forename: Hiroki
authors.initials: H
authors.lastname: Akamatsu
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005743:Gastrectomy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D008297:Male; D020360:Neoadjuvant Therapy; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery