title: Seroprevalence of Hepatitis E Among Boston Area Travelers, 2009-2010.
abstract: AbstractWe determined the prevalence of IgG antibodies to hepatitis E virus (anti-HEV IgG) among travelers attending Boston-area travel health clinics from 2009 to 2010. Pre-travel samples were available for 1,356 travelers, with paired pre- and post-travel samples for 450 (33%). Eighty of 1,356 (6%) pre-travel samples were positive for anti-HEV IgG. Compared with participants who had never lived in nor traveled to a highly endemic country, the pre-travel prevalence odds ratio (POR) of anti-HEV IgG among participants born in or with a history of previous travel to a highly endemic country was increased (POR = 4.8, 95% CI = 2.3-10.3 and POR = 2.6, 95% CI = 1.4-5.0, respectively). Among participants with previous travel to a highly endemic country, anti-HEV IgG was associated with age > 40 years (POR = 3.7, 95% CI = 1.3-10.2) and travel history to ≥ 3 highly endemic countries (POR = 2.7, 95% CI = 1.2-5.9). Two participants may have contracted HEV infection during their 2009-2010 trip.
authors.affiliation: National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.
authors.forename: Kira A
authors.initials: KA
authors.lastname: Barbre
authors.affiliation: National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.
authors.forename: Emily S
authors.initials: ES
authors.lastname: Jentes
authors.affiliation: National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC, Atlanta, Georgia.
authors.forename: Jan
authors.initials: J
authors.lastname: Drobeniuc
authors.affiliation: National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC, Atlanta, Georgia.
authors.forename: Saleem
authors.initials: S
authors.lastname: Kamili
authors.affiliation: Department of Global Health and Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts.|Section of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, Massachusetts.
authors.forename: Davidson H
authors.initials: DH
authors.lastname: Hamer
authors.affiliation: Department of Pediatrics, Boston Medical Center, Boston, Massachusetts.
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Barnett
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000097:blood*; D001900:Boston; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005260:Female; D014943:Global Health; D016751:Hepatitis E / Q000453:epidemiology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D000069078:Seroconversion; D016036:Seroepidemiologic Studies; D014195:Travel; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G