title: Radiation therapy and cancer control in developing countries: Can we save more lives?
abstract: Globally, morbidity and mortality due to cancer are predicted to increase in both men and women in the coming decades. Furthermore, it is estimated that two thirds of these cancer-related deaths will occur in low-and middle-income countries (LMIC). In addition to morbidity and mortality, cancer also causes an enormous economic burden, especially in developing countries. There are several treatment and management options for cancer including chemotherapy, radiation therapy, surgery, and palliative care. Radiotherapy or radiation therapy (RT) can be an effective treatment, especially for localized or solid cancers; about half of cancer patients receive radiation as a curative or palliative treatment. Because of its low cost, for patients from LMIC with inoperable tumors, RT may be the only option. With the overall increase in the number of cancer patients especially in resource-starved LMIC, the need for more RT facilities further affects the economic growth of those countries. Therefore, an advanced molecular-targeted and more integrated approach involving either RT alone or with surgery and improved cancer drug access worldwide are urgent needs for cancer care.
authors.affiliation: Sengkang General and Community Hospital, Singapore.
authors.forename: Rajamanickam
authors.initials: R
authors.lastname: Baskar
authors.affiliation: Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.
authors.forename: Koji
authors.initials: K
authors.lastname: Itahana
mesh_terms: D016923:Cell Death / Q000528:radiation effects; D003906:Developing Countries; D006801:Humans; D009369:Neoplasms / Q000191:economics / Q000453:epidemiology / Q000532:radiotherapy*; D011878:Radiotherapy / Q000191:economics / Q000379:methods* / Q000706:statistics & numerical data
keywords: Cancer; Cell death; Developing countries; Economic burden; Radiation therapy.