title: Silica gel microspheres decorated with covalent triazine-based frameworks as an improved stationary phase for high performance liquid chromatography.
abstract: A new stationary phase for high performance liquid chromatography (HPLC) applications based on silica gel microspheres decorated with covalent triazine-based frameworks (CTF-SiO2) composite has been reported here. In this new hybrid material, sheet-like covalent triazine-based frameworks (CTF) were grown onto the supporting silica spheres, in order to achieve improved chromatographic separation and selectivity. The new material was characterized by infrared spectroscopy, elemental analysis and thermogravimetric analysis. The chromatographic performance and retention mechanism of the new stationary phase were investigated in reversed-phase mode and compared against standard C18and cyano-modified silica (CN-SiO2) columns. A variety of different probe molecules were analyzed, including mono-substituted benzenes, polycyclic aromatic hydrocarbons, phenols, anilines and bases. The synergism of triazine and aromatic moieties provided several different retention mechanisms, thus improving the selectivity in the CTF-SiO2composite. The good column packing properties of the uniform silica microspheres combined with the separation ability of the CTF frameworks make the new CTF-SiO2material a potentially useful stationary phase for the analysis of complex samples.
authors.affiliation: School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450001, PR China; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: wjiezh@126.com.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, PR China.
authors.forename: Kai
authors.initials: K
authors.lastname: Hu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Chenchen
authors.initials: C
authors.lastname: Hu
authors.affiliation: Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, PR China.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Wang
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Ajuan
authors.initials: A
authors.lastname: Yu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: zsszz@126.com.
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D001554:Benzene / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D008863:Microspheres; D010636:Phenols / Q000737:chemistry; D011084:Polycyclic Aromatic Hydrocarbons / Q000737:chemistry; D015203:Reproducibility of Results; D058428:Silica Gel / Q000737:chemistry*; D014227:Triazines / Q000737:chemistry*
chemical_list: D010636:Phenols; D011084:Polycyclic Aromatic Hydrocarbons; D014227:Triazines; D058428:Silica Gel; D001554:Benzene
keywords: CTF–SiO(2) composite; High performance liquid chromatography; Improved separation; Multiple retention mechanisms; Stationary phase