title: Fragmentation of 120 and 200 MeV u-14He ions in water and PMMA targets.
abstract: Recently, the use of4He particles in cancer radiotherapy has been reconsidered as they potentially represent a good compromise between protons and12C ions. The first step to achieve this goal is the development of a dedicated treatment planning system, for which basic physics information such as the characterization of the beam lateral scattering and fragmentation cross sections are required. In the present work, the attenuation of4He primary particles and the build-up of secondary charged fragments at various depths in water and polymethyl methacrylate were investigated experimentally for 120 and 200 MeV u-1beams delivered by the synchrotron at the Heidelberg Ion-Beam Therapy Center, Heidelberg. Species and isotope identification was accomplished combining energy loss and time-of-flight measurements. Differential yields and energy spectra of all fragments types were recorded between 0° and 20° with respect to the primary beam direction.
authors.affiliation: GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany. TIFPA Trento Institute for Fundamental Physics and Applications-INFN Trento, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Rovituso
authors.forename: C
authors.initials: C
authors.lastname: Schuy
authors.forename: U
authors.initials: U
authors.lastname: Weber
authors.forename: S
authors.initials: S
authors.lastname: Brons
authors.forename: M A
authors.initials: MA
authors.lastname: Cortés-Giraldo
authors.forename: C
authors.initials: C
authors.lastname: La Tessa
authors.forename: E
authors.initials: E
authors.lastname: Piasetzky
authors.forename: D
authors.initials: D
authors.lastname: Izraeli
authors.forename: D
authors.initials: D
authors.lastname: Schardt
authors.forename: M
authors.initials: M
authors.lastname: Toppi
authors.forename: E
authors.initials: E
authors.lastname: Scifoni
authors.forename: M
authors.initials: M
authors.lastname: Krämer
authors.forename: M
authors.initials: M
authors.lastname: Durante
mesh_terms: D006371:Helium / Q000737:chemistry* / Q000627:therapeutic use*; D006801:Humans; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D012062:Relative Biological Effectiveness; D017356:Synchrotrons / Q000295:instrumentation*; D014867:Water / Q000737:chemistry*
chemical_list: D014867:Water; D006371:Helium; D019904:Polymethyl Methacrylate