title: Seroepidemiology of hepatitis B and C virus infections among blood donors in Ethiopia.
abstract: This study was conducted to investigate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among blood donors in different regions in Ethiopia. A total of 56 885 sera were tested for HBsAg and anti-HCV antibodies. Of these, 3.9% were found HBsAg-positive, 0.52% anti-HCV-positive, and 0.054% dual positive. HBV prevalence was relatively higher in Adama (5.91%) than Gondar (4.05%), Jimma (3.87%), Addis Ababa (3.75%), and Tigray (3.7%); and in males (4.64%) than females (2.1%). Overall, HBV and HCV prevalence increased with age. In conclusion, HBV and HCV seroprevalence among blood donors in Ethiopia is intermediate and low, respectively.
authors.affiliation: Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: Gadissa Bedada
authors.identifier: 0000-0002-5627-9675
authors.initials: GB
authors.lastname: Hundie
authors.affiliation: Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: Victor Stalin
authors.initials: VS
authors.lastname: Raj
authors.affiliation: National Blood Bank Services, Ministry of Health, Addis Ababa, Ethiopia.
authors.forename: Daniel
authors.initials: D
authors.lastname: GebreMichael
authors.affiliation: Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: Bart L
authors.initials: BL
authors.lastname: Haagmans
mesh_terms: D000328:Adult; D001782:Blood Donors; D003430:Cross-Sectional Studies; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D016174:Hepacivirus / Q000276:immunology / Q000302:isolation & purification; D006509:Hepatitis B / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006515:Hepatitis B virus / Q000276:immunology / Q000302:isolation & purification; D006526:Hepatitis C / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies; D012737:Sex Factors; D055815:Young Adult
chemical_list: D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies
keywords: HBV; HCV; ethiopia; seroepidemiology