title: Lighting Up ERK Activity.
abstract: Activation of extracellular signal regulated kinase (ERK) is used by many signaling pathways to control tissue patterning in a broad range of multicellular organisms. In this issue of Developmental Cell, Johnson et al. (2017) provide an optogenetic approach to manipulate this pathway with high precision and explore its signaling code.
authors.affiliation: Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: benny.shilo@weizmann.ac.il.
authors.forename: Ben-Zion
authors.initials: BZ
authors.lastname: Shilo
authors.affiliation: Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
authors.forename: Naama
authors.initials: N
authors.lastname: Barkai
mesh_terms: D004789:Enzyme Activation; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism*; D008027:Light; D020935:MAP Kinase Signaling System; D062308:Optogenetics; D010766:Phosphorylation; D015398:Signal Transduction
chemical_list: D048049:Extracellular Signal-Regulated MAP Kinases