title: [A clinical case of long-term macitentan therapy in a female patient with idiopathic pulmonary hypertension].
abstract: In late 2015, the Russian Federation registered the new non-selective endothelin receptor antagonist macitentan for the pathogenetic therapy of pulmonary arterial hypertension. The given clinical case demonstrates the possibility of using macitentan in a female patient with idiopathic pulmonary hypertension and its ability to affect the clinical, hemodynamic, and functional status of patients and to slow down the progression of the disease.
authors.affiliation: A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research and Production Complex, Ministry of Health of Russia, Moscow, Russia.
authors.forename: O A
authors.initials: OA
authors.lastname: Arkhipova
authors.affiliation: A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research and Production Complex, Ministry of Health of Russia, Moscow, Russia.
authors.forename: T V
authors.initials: TV
authors.lastname: Martynyuk
authors.affiliation: A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research and Production Complex, Ministry of Health of Russia, Moscow, Russia.
authors.forename: I E
authors.initials: IE
authors.lastname: Chazova
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D018450:Disease Progression; D004452:Echocardiography / Q000379:methods; D065128:Endothelin Receptor Antagonists / Q000008:administration & dosage / Q000009:adverse effects; D065627:Familial Primary Pulmonary Hypertension / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D011743:Pyrimidines / Q000008:administration & dosage / Q000009:adverse effects; D013449:Sulfonamides / Q000008:administration & dosage / Q000009:adverse effects; D013995:Time; D016896:Treatment Outcome
chemical_list: D065128:Endothelin Receptor Antagonists; D011743:Pyrimidines; D013449:Sulfonamides; C533860:macitentan