title: [Successful Multidisciplinary Treatment of Metastatic Ovarian Cancer after Perforative Peritonitis of the Rectum Due to Disseminated Ovarian Cancer].
abstract: A72 -year-old woman who complained of abdominal pain and distention visited the emergency clinic of our hospital in April 2014. Computed tomography(CT)showed an omental mass and a pelvic mass with massive ascites. The fluid was removed by abdominal aspiration, and the patient showed perforative peritonitis next day. An emergency operation was performed. The surgical operation showed that the rectum was perforated due to stenosis covered by the ovarian cancer metastases. Aleft colectomy combined with a transverse colostomy was performed. After 4 weeks of rest, 6 courses of tri- weekly TC chemotherapy were administered, and the CA125 level decreased from 140 U/mL to 11.8 U/mL. She underwent a complete cytoreductive surgery in February 2015. She was histologically diagnosed with Grade 2b serous adenocarcinoma. After these 2 surgical operations, she underwent a splenectomy to remove a single metastasis in February 2016 and consecutive chemotherapy. For ovarian cancer, if dissemination occurs, rectal perforation can be a treatment target with a gastrointestinal surgeon's help.
authors.affiliation: Dept. of Surgery, Seikeikai Hospital.
authors.forename: Taiping
authors.initials: T
authors.lastname: Huang
authors.forename: Makoto
authors.initials: M
authors.lastname: Nakamuro
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakano
authors.forename: Yuhei
authors.initials: Y
authors.lastname: Okubo
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kondo
authors.forename: Kazuo
authors.initials: K
authors.lastname: Ishikawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furukawa
authors.forename: Ichiro
authors.initials: I
authors.lastname: Amakawa
authors.forename: Koichi
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Kozo
authors.initials: K
authors.lastname: Kadowaki
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ohta
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001201:Ascites / Q000209:etiology; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D010538:Peritonitis / Q000209:etiology*; D012004:Rectal Neoplasms / Q000556:secondary / Q000601:surgery