title: The course of anxiety, depression and unmet needs in survivors of diffuse large B cell lymphoma and multiple myeloma in the early survivorship period.
abstract: OBJECTIVE
  The purpose of the study is to examine the course of anxiety, depression and unmet needs in diffuse large B cell lymphoma (DLBCL) and multiple myeloma (MM) survivors in the first 2 years post diagnosis.
  
  
  METHODS
  DLBCL and MM survivors, recruited through the Victorian Cancer Registry, completed two interviews approximately 7 and 15 months post diagnosis. Hospital Anxiety and Depression Scale (HADS) and Supportive Care Needs Survey (SCNS-SF34) were completed at both interviews. Primary outcomes were prevalence of anxiety, depression and unmet needs (any or moderate-high). Generalized estimating equation examined whether course of anxiety, depression and unmet needs differed between the two cancers.
  
  
  RESULTS
  Overall, 236 DLBCL and 178 MM survivors completed both telephone interviews. Course of anxiety differed (p < 0.01) with rate increasing in DLBCL (14 to 22%) while remaining stable for MM (15 to 12%). Course of depression also differed (p < 0.01), decreasing for MM (22 to 12%) and remaining stable for DLBCL (15 to 16%) survivors. Change in unmet needs was generally similar for the two cancer groups, except for moderate to high psychological needs (p < 0.05).
  
  
  CONCLUSIONS
  Patterns of change in anxiety and depression in first 2 years post diagnosis differ for DLBCL and MM survivors.
  
  
  CONCLUSIONS
  Studying psychological outcomes in mixed haematological cancer samples may be inappropriate, at least in the early survivorship phase. Separate studies of the experiences of people with the different haematological cancer subtypes are needed to ensure psychosocial and supportive care interventions are appropriate to the needs of individuals with different haematological cancers.
authors.affiliation: Cancer Council Victoria, 615 St. Kilda Road, Melbourne, VIC, 3004, Australia.
authors.forename: Devesh
authors.initials: D
authors.lastname: Oberoi
authors.affiliation: Cancer Council Victoria, 615 St. Kilda Road, Melbourne, VIC, 3004, Australia. Vicki.whtie@cancervic.org.au.|The University of Melbourne, Parkville, VIC, 3010, Australia. Vicki.whtie@cancervic.org.au.
authors.forename: Victoria
authors.initials: V
authors.lastname: White
authors.affiliation: The University of Melbourne, Parkville, VIC, 3010, Australia.|Peter MacCallum Cancer Centre, 305 Grattan St., Melbourne, VIC, 3000, Australia.
authors.forename: John
authors.initials: J
authors.lastname: Seymour
authors.affiliation: The University of Melbourne, Parkville, VIC, 3010, Australia.|Peter MacCallum Cancer Centre, 305 Grattan St., Melbourne, VIC, 3000, Australia.
authors.forename: H Miles
authors.initials: HM
authors.lastname: Prince
authors.affiliation: The University of Melbourne, Parkville, VIC, 3010, Australia.|Peter MacCallum Cancer Centre, 305 Grattan St., Melbourne, VIC, 3000, Australia.
authors.forename: Simon
authors.initials: S
authors.lastname: Harrison
authors.affiliation: The University of Melbourne, Parkville, VIC, 3010, Australia.|Peter MacCallum Cancer Centre, 305 Grattan St., Melbourne, VIC, 3000, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Jefford
authors.affiliation: Royal Melbourne Hospital Familial Cancer Centre, Level 2, Royal Melbourne Hospital, Grattan Street, Parkville, VIC, 3052, Australia.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Winship
authors.affiliation: Cancer Council Victoria, 615 St. Kilda Road, Melbourne, VIC, 3004, Australia.|The University of Melbourne, Parkville, VIC, 3010, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Hill
authors.affiliation: Austin Health, Suite 5 210 Burgundy Street, Heidelberg, VIC, 3084, Australia.
authors.forename: Damien
authors.initials: D
authors.lastname: Bolton
authors.affiliation: North Eastern Melbourne Integrated Cancer Service, 145 Studley Rd, Heidelberg, VIC, 3084, Australia.
authors.forename: Anne
authors.initials: A
authors.lastname: Kay
authors.affiliation: AlfredHealth, The Alfred, 55 Commercial Road, Melbourne, VIC, 3004, Australia.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Millar
authors.affiliation: Concord Hospital, Hospital Rd., Concord, NSW, 2139, Australia.
authors.forename: Nicole Wong
authors.initials: NW
authors.lastname: Doo
authors.affiliation: Cancer Council Victoria, 615 St. Kilda Road, Melbourne, VIC, 3004, Australia.
authors.forename: Graham
authors.initials: G
authors.lastname: Giles
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000209:etiology*; D003863:Depression / Q000209:etiology*; D005260:Female; D006301:Health Services Needs and Demand; D006801:Humans; D008137:Longitudinal Studies; D016393:Lymphoma, B-Cell / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000523:psychology*; D020380:Needs Assessment; D011795:Surveys and Questionnaires; D015996:Survival Rate; D017741:Survivors / Q000523:psychology*; D055815:Young Adult
keywords: Cancer survivorship; Diffuse large B cell lymphoma; Haematological cancer; Multiple myeloma; Psychosocial oncology