title: In Silico Analysis of the Biomechanical Stability of Commercially Pure Ti and Ti-15Mo Plates for the Treatment of Mandibular Angle Fracture.
abstract: OBJECTIVE
  To investigate the influence of different materials and fixation methods on maximum principal stress (MPS) and displacement in reconstruction plates using in silico 3-dimensional finite element analysis (3D-FEA).
  
  
  METHODS
  Computer-assisted designed (CAD) models of the mandible and teeth were constructed. Champy and AO/ASIF plates and fixation screws were designed with CAD software. 3D-FEA was performed by image-based CAE software. Maximum and minimum values of biomechanical stability, MPS, and displacement distribution were compared in Champy and AO/ASIF plates made from commercially pure titanium grade 2 (cp-Ti) and a titanium-and-molybdenum (14.47% wt) alloy (Ti-15Mo).
  
  
  RESULTS
  For plates fixed on a model of a fractured left angle of the mandible, the maximum and minimum values of MPS in the cp-Ti-constructed Champy plate, upper AO/ASIF plate, and lower AO/ASIF plate were 19.5 and 20.3%, 15.2 and 25.3%, and 21.4 and 4.6% lower, respectively, than those for plates made from Ti-15Mo. In the same model, the maximum and minimum values of displacement in the cp-Ti-constructed Champy plate, upper AO/ASIF plate, and lower AO/ASIF plate were 1.6 and 3.8%, 3.1 and 2.7%, and 5.4 and 10.4% higher, respectively, than those for plates made from Ti-15Mo.
  
  
  CONCLUSIONS
  This in silico 3D-FEA shows that Ti-15Mo plates have greater load-bearing capability.
authors.affiliation: Associate Professor, Department of Biomaterials Science, Osaka University Graduate School of Dentistry, Osaka, Japan. Electronic address: yamagu@dent.osaka-u.ac.jp.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamaguchi
authors.affiliation: Assistant Professor, Centro Universotário do Norte Paulista (UNORP), São José do Rio Preto, SP, Brazil.
authors.forename: Rodolfo B
authors.initials: RB
authors.lastname: Anchieta
authors.affiliation: Postdoctoral Research Fellow, Faculdade de Odontologia de Araraquara, UNESP - Universidate Estadual Paulista, Araraquara, SP, Brazil.
authors.forename: Fernando P S
authors.initials: FPS
authors.lastname: Guastaldi
authors.affiliation: Assistant Professor, Department of Biomaterials and Biomimetics, New York University, New York, NY.
authors.forename: Nick
authors.initials: N
authors.lastname: Tovar
authors.affiliation: Assistant Professor, Department of Mechanical and Systems Engineering, Ryukoku University, Shiga, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tawara
authors.affiliation: Professor, Department of Biomaterials Science, Osaka University Graduate School of Dentistry, Osaka, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Imazato
authors.affiliation: Associate Professor, Department of Biomaterials and Biomimetics, New York University, New York, NY.
authors.forename: Paulo G
authors.initials: PG
authors.lastname: Coelho
mesh_terms: D001696:Biomechanical Phenomena; D001860:Bone Plates; D003198:Computer Simulation; D006801:Humans; D008337:Mandibular Fractures / Q000601:surgery*; D019637:Orthopedic Procedures / Q000379:methods; D019651:Plastic Surgery Procedures / Q000379:methods; D014025:Titanium
chemical_list: D014025:Titanium