title: [Differences in Related Risk Factors for Severe Postoperative Complications and Prognosis between Male and Female Gastric Cancer Patients].
abstract: OBJECTIVE
  Little is known about sex-based differences in morbidity and prognosis after gastrectomy for gastric cancer. This study was designed to detect risk factors for severe postoperative complications and define prognosis according to sex after gastrectomy for gastric cancer.
  
  
  METHODS
  Consecutive patients comprising 878 male and 421 female patients, who underwent R0 gastrectomy for Stage I - III gastric cancer, were retrospectively analyzed. We defined patients with severe postoperative complications as those with anastomotic leakage, a pancreatic fistula, and/or an intra-abdominal abscess of grade> II according to the Clavien-Dindo classification.
  
  
  RESULTS
  There was a significant association between sex and severe postoperative complications after gastrectomy for gastric cancer. In the male patients, poor nutrition, open surgery, and disease progression were independent risk factors for severe postoperative complications. In female patients, disease progression was the only independent risk factor. Regarding prognosis, poor nutrition was the only independent poor prognostic factor in male patients.
  
  
  CONCLUSIONS
  Risk factors for severe postoperative complications were different between the male and female patients. Particularly in male patients, careful nutritional support may be required to prevent severe complications and improve the prognosis.
authors.affiliation: Division of Digestive Surgery, Dept. of Surgery, Kyoto Prefectural University of Medicine.
authors.forename: Jun
authors.initials: J
authors.lastname: Kiuchi
authors.forename: Shuhei
authors.initials: S
authors.lastname: Komatsu
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ichikawa
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kosuga
authors.forename: Kazuma
authors.initials: K
authors.lastname: Okamoto
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Arita
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Konishi
authors.forename: Ryo
authors.initials: R
authors.lastname: Morimura
authors.forename: Yasutoshi
authors.initials: Y
authors.lastname: Murayama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shiozaki
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kuriu
authors.forename: Hisashi
authors.initials: H
authors.lastname: Ikoma
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Nakanishi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Eigo
authors.initials: E
authors.lastname: Otsuji
mesh_terms: D000368:Aged; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000601:surgery