title: Phytochemistry and pharmacology ofFerula persicaBoiss.: A review.
abstract: Ferula persica, is the well-known species of the genusFerulain Iran and has two varieties:persicaandlatisecta. They have both been extensively used in traditional medicine for a wide range of ailments. A great number of chemical compounds including sesquiterpene coumarins and polysulfides have been isolated from this plant. Fresh plant materials, crude extracts and isolated components ofF. persicahave shown a wide spectrum of pharmacological properties including anti-pigmentation inSerratia marcescens, cytotoxic, antibacterial, anti-fungal, anti-leishmanial, cancer chemopreventive, reversal of multi-drug resistance, anti-inflammatory and lipoxygenase inhibitory activity. The present review summarizes the data available regarding the chemical constituents and biological activities ofF. persica.
authors.affiliation: Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Zohreh
authors.initials: Z
authors.lastname: Sattar
authors.affiliation: Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Iranshahi
keywords: Apiaceae; Ferula persica Sesquiterpene coumarins; Sulfur-containing – compounds; Umbelliprenin