title: HUGE RENAL ANGIOMYOLIPOMA (AML) IN TUBEROUS SCLEROSIS COMPLEX (TSC) WHICH IS CONTROLED BY EVEROLIMUS: A CASE REPORT.
abstract: We report a 43-year-old TSC man with repeated hemorrhage of bilateral renal AML. He was diagnosed with TSC based on the findings of facial angiofibroma, mental retardation and epilepsy in childhood. In 2011, he experienced three times in AML-associated hemorrhage from the left kidney and received selective transarterial embolotherapy (TAE). In 2013, he also experienced AML-associated hemorrhage from the right kidney and received selective TAE. To control his AML, treatments with Everolimus was started and well tolerated. So far, his renal AML remarkably shrunk without retroperitoneal hemorrhage for 24 months, while he had some episode of side effect.
authors.affiliation: Department of Urology, Tsuyama Chuo Hospital.
authors.forename: Taiki
authors.initials: T
authors.lastname: Kanbara
authors.forename: Kazuma
authors.initials: K
authors.lastname: Sakaeda
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Kusaka
authors.forename: Naoki
authors.initials: N
authors.lastname: Akebi
mesh_terms: D000328:Adult; D018207:Angiomyolipoma / Q000188:drug therapy* / Q000209:etiology; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001921:Brain / Q000000981:diagnostic imaging; D000068338:Everolimus / Q000008:administration & dosage* / Q000009:adverse effects; D006470:Hemorrhage / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000209:etiology; D007970:Leukopenia / Q000139:chemically induced; D008297:Male; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014402:Tuberous Sclerosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D000068338:Everolimus