title: Contact Burn with Blister Formation in Children Treated with Sennosides.
abstract: Eight children treated for severe constipation with sennosides unexpectedly developed contact burns with blisters secondary to the use of these laxatives. All patients wore diapers, and the injuries occurred overnight. To avoid this side effect, we recommend that patients treated with sennosides, especially those in diapers, receive the medication at a time that allows for bowel movements to occur during the day and not overnight.
authors.affiliation: Colorectal Center for Children, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Kimberly
authors.initials: K
authors.lastname: Cogley
authors.affiliation: Colorectal Center for Children, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Andrea
authors.initials: A
authors.lastname: Echevarria
authors.affiliation: Colorectal Center for Children, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Catalina
authors.initials: C
authors.lastname: Correa
authors.affiliation: Colorectal Center for Children, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
authors.forename: Luis
authors.identifier: http://orcid.org/0000-0002-1193-1316
authors.initials: L
authors.lastname: De la Torre-Mondragón
mesh_terms: D001768:Blister / Q000209:etiology* / Q000473:pathology; D002056:Burns / Q000209:etiology* / Q000473:pathology; D002400:Cathartics / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003248:Constipation / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D054368:Laxatives / Q000009:adverse effects*; D012676:Senna Extract / Q000009:adverse effects*
chemical_list: D002400:Cathartics; D054368:Laxatives; D012676:Senna Extract