title: Importance of producing economic compounds to combat cancer.
abstract: The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost.
authors.affiliation: Laboratorio de Ecología Molecular Microbiana, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla, Ciudad Universitaria, Edificio 103 J, San Manuel, Puebla, CP, 72570, México.
authors.forename: Jesús
authors.identifier: 0000-0002-1151-9778
authors.initials: J
authors.lastname: Muñoz-Rojas
mesh_terms: D030008:Catharanthus; D006801:Humans; D009369:Neoplasms; D014747:Vinblastine
chemical_list: D014747:Vinblastine