title: Hypercholesterolaemia screening in Type 1 diabetes: a difference of opinion.
abstract: To assess cholesterol screening of children with Type 1 diabetes by diabetes professionals using a survey of current practice, given that National Institute of Health and Care Excellence guidelines on childhood Type 1 diabetes do not recommend cholesterol screening, yet the National Paediatric Diabetes Audit has an annual cholesterol measure (> 12 years) as a key outcome indicator.
  
  
  
  An online survey was sent to 280 members of the Association of Children's Diabetes Clinicians to assess cholesterol screening practice in children.
  
  
  
  A total of 87 diabetes professionals (31%) responded. The results showed that 94% of respondents measured cholesterol, 33% did this annually on all children, and 7% measured fasting cholesterol. A total of 63% used no guidelines to decide treatment or further investigation. The definition of 'high' cholesterol varied from > 4.5 to > 8 mmol/l, with 40% giving no response or specific level. Only 14% of clinicians had started statin therapy in their diabetes clinic in the previous 5 years.
  
  
  
  Whilst the majority of diabetes professionals measured cholesterol in children with Type 1 diabetes, there was marked variability in sampling, in children screened and in action taken if levels were considered abnormal. It is debatable whether cholesterol measures should be undertaken, certainly more than once, and whether cholesterol level should feature as a key outcome in the national audit in future.
authors.affiliation: Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK.|Biomedical Research Unit in Nutrition, Diet and Lifestyle, School of Oral and Dental Sciences, University of Bristol, Bristol, UK.
authors.forename: T
authors.initials: T
authors.lastname: Candler
authors.affiliation: Biomedical Research Unit in Nutrition, Diet and Lifestyle, School of Oral and Dental Sciences, University of Bristol, Bristol, UK.
authors.forename: O
authors.initials: O
authors.lastname: Mahmoud
authors.affiliation: Oxford Children's Hospital, Oxford, UK.
authors.forename: J
authors.initials: J
authors.lastname: Edge
authors.affiliation: Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK.|Biomedical Research Unit in Nutrition, Diet and Lifestyle, School of Oral and Dental Sciences, University of Bristol, Bristol, UK.
authors.forename: J
authors.initials: J
authors.lastname: Hamilton-Shield
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002657:Child Development; D002784:Cholesterol / Q000097:blood*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications*; D019538:Health Care Surveys; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D020407:Internet; D008403:Mass Screening; D000072143:Pediatricians; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D012955:Societies, Medical; D006113:United Kingdom
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D002784:Cholesterol