title: Prevention and treatment of diabetic foot ulcers.
abstract: The rising prevalence of diabetes estimated at 3.6 million people in the UK represents a major public health and socioeconomic burden to our National Health Service. Diabetes and its associated complications are of a growing concern. Diabetes-related foot complications have been identified as the single most common cause of morbidity among diabetic patients. The complicating factor of underlying peripheral vascular disease renders the majority of diabetic foot ulcers asymptomatic until latter evidence of non-healing ulcers become evident. Therefore, preventative strategies including annual diabetic foot screening and diabetic foot care interventions facilitated through a multidisciplinary team have been implemented to enable early identification of diabetic patients at high risk of diabetic foot complications. The National Diabetes Foot Care Audit reported significant variability and deficiencies of care throughout England and Wales, with emphasis on change in the structure of healthcare provision and commissioning, improvement of patient education and availability of healthcare access, and emphasis on preventative strategies to reduce morbidities and mortality of this debilitating disease. This review article aims to summarise major risk factors contributing to the development of diabetic foot ulcers. It also considers the key evidence-based strategies towards preventing diabetic foot ulcer. We discuss tools used in risk stratification and classifications of foot ulcer.
authors.affiliation: 1 Diabetes Centre, Aintree University Hospital, Liverpool L9 7AL, UK.
authors.forename: Jonathan Zhang Ming
authors.initials: JZ
authors.lastname: Lim
authors.affiliation: 2 Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK.
authors.forename: Natasha Su Lynn
authors.initials: NS
authors.lastname: Ng
authors.affiliation: 1 Diabetes Centre, Aintree University Hospital, Liverpool L9 7AL, UK.
authors.forename: Cecil
authors.initials: C
authors.lastname: Thomas
mesh_terms: D017719:Diabetic Foot / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy*; D006801:Humans; D008403:Mass Screening; D012307:Risk Factors; D014945:Wound Healing
keywords: diabetic foot ulcer; growth factor; offloading; wound debridement; wound dressing