title: Crouzon's Syndrome: A Rare Genetic Disorder.
abstract: Crouzon's syndrome, also known as brachial arch syndrome, is an autosomal dominant disorder with complete penetrance and variable expressivity. Described by a French neurosurgeon in 1912, it is a rare genetic disorder. Crouzon's syndrome is caused by mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. Normally, the sutures in the human skull fuse after the complete growth of the brain, but if any of these sutures close early, then it may interfere with the growth of the brain. The disease is characterized by craniosynostosis, with associated dentofacial anomalies. This report describes the different clinical features in a 10-year-old male patient, with particular reference to characteristic findings of this syndrome.
  Kaushik A, Bhatia H, Sharma N. Crouzon's Syndrome: A Rare Genetic Disorder. Int J Clin Pediatr Dent 2016;9(4):384-387.
authors.affiliation: Senior Lecturer, Department of Pedodontics and Preventive Dentistry, MN DAV Dental College, Solan, Himachal Pradesh, India.
authors.forename: Anupriya
authors.initials: A
authors.lastname: Kaushik
authors.affiliation: Professor and Head, Department of Pedodontics and Preventive Dentistry, Manav Rachna Dental College, Faridabad, Haryana, India.
authors.forename: Hindpal
authors.initials: H
authors.lastname: Bhatia
authors.affiliation: Reader, Department of Pedodontics and Preventive Dentistry, Manav Rachna Dental College, Faridabad, Haryana, India.
authors.forename: Naresh
authors.initials: N
authors.lastname: Sharma
keywords: Crouzon’s syndrome; Fibroblast growth factor; Premature synostosis.