title: The essential oil from the fruits of the Brazilian spice Xylopia sericea A. St.-Hil. presents expressive in-vitro antibacterial and antioxidant activity.
abstract: OBJECTIVE
  The aims of this study were to investigate the chemical composition and the antioxidant activity and antibacterial activity of the essential oil of Xylopia sericea fruits (OXS). The fruits of this species are popularly used for medicinal purposes, and as a condiment in food preparation.
  
  
  METHODS
  The chemical composition of OXS was analysed by GC/MS. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) scavenging, β-carotene/linoleic acid bleaching and phosphomolybdenum and thiobarbituric acid-reactive substance (TBARS) assays were used to evaluate the antioxidant activity. Antibacterial activity was assessed by minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against bacterial strains of interest to human health and food spoilage.
  
  
  RESULTS
  Eighty-four compounds were identified. The sesquiterpenes spathulenol (16.42%), guaiol (13.93%) and germacrene D (8.11%) were the most abundant constituents. OXS presented a significant antioxidant activity and also a high bacteriostatic effect against Staphylococcus aureus, Enterobacter cloacae, Bacillus cereus and Klebsiella pneumoniae.
  
  
  CONCLUSIONS
  Those results evidenced the potential of OXS to treat human bacterial infections and as an antimicrobial ingredient for food preservation.
authors.affiliation: Laboratory of Bioactive Natural Products, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Renata de F
authors.initials: RF
authors.lastname: Mendes
authors.affiliation: Laboratory of Bioactive Natural Products, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Nícolas de C C
authors.initials: NC
authors.lastname: Pinto
authors.affiliation: Laboratory of Bioactive Natural Products, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Josiane M
authors.initials: JM
authors.lastname: da Silva
authors.affiliation: Laboratory of Bioactive Natural Products, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Jucélia B
authors.initials: JB
authors.lastname: da Silva
authors.affiliation: Laboratory of Bioactive Natural Products, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Raquel C Dos S
authors.initials: RC
authors.lastname: Hermisdorf
authors.affiliation: Laboratory of Bioactive Natural Products, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Rodrigo L
authors.initials: RL
authors.lastname: Fabri
authors.affiliation: Department of Botany, Biological Sciences Institute, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Luciana M
authors.initials: LM
authors.lastname: Chedier
authors.affiliation: Laboratory of Bioactive Natural Products, Department of Biochemistry, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.
authors.forename: Elita
authors.initials: E
authors.lastname: Scio
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001713:Biphenyl Compounds / Q000737:chemistry / Q000494:pharmacology; D001938:Brazil; D005638:Fruit / Q000737:chemistry*; D008826:Microbial Sensitivity Tests / Q000379:methods; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D010851:Picrates / Q000737:chemistry / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology; D045788:Sesquiterpenes, Germacrane / Q000737:chemistry / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane; D054336:Xylopia / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D009822:Oils, Volatile; D010851:Picrates; D010936:Plant Extracts; D010938:Plant Oils; D012717:Sesquiterpenes; D045788:Sesquiterpenes, Germacrane; D045789:Sesquiterpenes, Guaiane; C010574:biphenyl; C013258:spathulenol; C004931:1,1-diphenyl-2-picrylhydrazyl; C469146:guaiol; C027259:germacrene D
keywords: 
  Xylopia sericea
  ; bacterial infections; essential oil; food preservation