title: Synthesis of Furandicarboxylic Acid Esters From Nonfood Feedstocks Without Concomitant Levulinic Acid Formation.
abstract: 5-Hydroxymethylfurfural (HMF) is a versatile intermediate in biomass conversion pathways. However, the notoriously unstable nature of HMF imposes challenges to design selective routes to chemicals such as furan-2,5-dicarboxylic acid (FDCA). Here, a new strategy for obtaining furans is presented, bypassing the formation of the unstable HMF. Instead of starting with glucose/fructose and thus forming HMF as an intermediate, the new route starts from uronic acids, which are abundantly present in many agro residues such as sugar beet pulp, potato pulp, and citrus peels. Conversion of uronic acids, via ketoaldonic acids, to the intermediate formylfuroic acid (FFA) esters, and subsequently to FDCA esters, proceeds without formation of levulinic acid or insoluble humins. This new route provides an attractive strategy to valorize agricultural waste streams and a route to furanic building blocks without the co-production of levulinic acid or humins.
authors.affiliation: Wageningen University Biobased Chemistry and Technology, Bornse Weilanden 9, 6708WG, Wageningen, The Netherlands.|Wageningen Food & Biobased Research, Bornse Weilanden 9, 6708WG, Wageningen, The Netherlands.
authors.forename: Frits
authors.initials: F
authors.lastname: van der Klis
authors.affiliation: Wageningen Food & Biobased Research, Bornse Weilanden 9, 6708WG, Wageningen, The Netherlands.
authors.forename: Jacco
authors.initials: J
authors.lastname: van Haveren
authors.affiliation: Wageningen Food & Biobased Research, Bornse Weilanden 9, 6708WG, Wageningen, The Netherlands.
authors.forename: Daan S
authors.initials: DS
authors.lastname: van Es
authors.affiliation: Wageningen University Biobased Chemistry and Technology, Bornse Weilanden 9, 6708WG, Wageningen, The Netherlands.
authors.forename: Johannes H
authors.initials: JH
authors.lastname: Bitter
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D003998:Dicarboxylic Acids / Q000138:chemical synthesis* / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry*; D007536:Isomerism; D007982:Levulinic Acids / Q000737:chemistry*; D010084:Oxidation-Reduction; D012997:Solvents / Q000737:chemistry
chemical_list: D003998:Dicarboxylic Acids; D004952:Esters; D005663:Furans; D007982:Levulinic Acids; D012997:Solvents; C551400:2,5-furandicarboxylic acid; C032246:levulinic acid
keywords: furandicarboxylic acid; isomerization; levulinic acid; oxidation; uronic acids