title: [An Elderly Colon Cancer Patient with Multiple Liver Metastases Who Was Successfully Treated Using mFOLFOX6 and sLV5FU2 Chemotherapy - A Case Report].
abstract: Curative treatment for unresectable colon cancer is difficult, and therefore, chemotherapy is often administered in an attempt to improve the prognosis. However, the safety andfeasibility of chemotherapy for elderly patients over 80-years-old have not yet been clarified. We report an elderly colon cancer patient with multiple liver metastases who was successfully treatedwith mFOLFOX6 andsLV5 FU2 chemotherapy. The patient was an 83-year-old-man who was referredto our hospital. After performing sigmoidectomy, we administered mFOLFOX6 chemotherapy. After 5 courses, the regimen was changed to sLV5FU2 owing to grade 3 neuropathy. Liver metastases disappearedanda complete response was obtained1 year after chemotherapy administration. Twenty-four courses of sLV5FU2 chemotherapy had been safely performed. Although grade 1 neutropenia developed, no other adverse event was observed. Currently, the patient is alive without recurrence. Chemotherapy for elderly patients is both feasible and safe.
authors.affiliation: Dept. of Surgery, Kinan Hospital.
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Miyazaki
authors.forename: Kazuo
authors.initials: K
authors.lastname: Yamabe
authors.forename: Nobuyasu
authors.initials: N
authors.lastname: Hayashi
authors.forename: Toshiya
authors.initials: T
authors.lastname: Michiura
authors.forename: Tomo
authors.initials: T
authors.lastname: Nakagawa
authors.forename: Keita
authors.initials: K
authors.lastname: Okubo
authors.forename: Shigeo
authors.initials: S
authors.lastname: Fujita
authors.forename: Makio
authors.initials: M
authors.lastname: Nagaoka
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D012074:Remission Induction; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome