title: Impact of Wheatgrass (Triticum aestivum L.) Supplementation on Atherogenic Lipoproteins and Menopausal Symptoms in Hyperlipidemic South Asian Women - A Randomized Controlled Study.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the effect of wheatgrass (Triticum aestivum L.) on atherogenic lipoproteins, inflammation, and menopausal symptoms.
  
  
  METHODS
  Fifty-nine hyperlipidemic women were randomized into control (n = 30) and intervention groups (n = 29). Intervention group was administered 3.5 g of freeze-dried wheatgrass powder in encapsulated form daily for 10 weeks, while the control group received no intervention.
  
  
  RESULTS
  The intervention group experienced a reduction of 5.4% in total cholesterol (TC), 4.4% in low-density lipoprotein cholesterol, and 9.5% in triacylglycerols (TAG); however, high-density lipoprotein (HDL) also reduced by 6% following 10 weeks of intervention. Compared with the control group, the baseline-adjusted post-intervention levels of TC, TAG, and Apolipoprotein B (Apo B) were significantly lower in the experimental group compared with the control group (p = 0.043, 0.045, and 0.016, respectively). Prevalence of menopausal symptoms saw nonsignificant reductions: vasomotor, 42%; somatic, 33%; and psychological, 50%, while urogenital symptoms remained unaltered.
  
  
  CONCLUSIONS
  Wheatgrass supplementation at a dose of 3.5 g per day for a period of 10 weeks results in significant reductions in Apo B fraction, TC, and TAG without significantly reducing the HDL cholesterol.
authors.affiliation: a Department of Foods & Nutrition , Faculty of Family and Community Sciences, The Maharaja Sayajirao University of Baroda , Vadodara , Gujarat , India.
authors.forename: Nitya
authors.initials: N
authors.lastname: Kumar
authors.affiliation: a Department of Foods & Nutrition , Faculty of Family and Community Sciences, The Maharaja Sayajirao University of Baroda , Vadodara , Gujarat , India.
authors.forename: Uma
authors.initials: U
authors.lastname: Iyer
mesh_terms: D000328:Adult; D001055:Apolipoproteins B / Q000097:blood; D002784:Cholesterol / Q000097:blood; D019587:Dietary Supplements; D004339:Drug Compounding; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000628:therapy*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008593:Menopause / Q000097:blood*; D008875:Middle Aged; D011208:Powders / Q000008:administration & dosage*; D014280:Triglycerides / Q000097:blood; D014908:Triticum
chemical_list: D001055:Apolipoproteins B; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D011208:Powders; D014280:Triglycerides; D002784:Cholesterol
keywords: South Asian women; atherogenicity; hyperlipidemic; inflammation; menopausal symptoms; wheatgrass