title: Isolation and characterization of a novel dithio-carbodenafil analogue from a health supplement.
abstract: A novel dithio-carbodenafil compound was isolated and identified from a health supplement. The structure of the unknown compound has been characterized using LC-UV, Fourier Transform Infrared (FTIR), high-resolution mass spectrometry, 1D and 2D nuclear magnetic resonance (NMR) spectroscopy. It has been revealed as 3,5-dimethylpiperazinyl dithio-desmethylcarbodenafil as a result of two additional methyl groups on the piperazine ring.
authors.affiliation: Pharmaceutical Laboratory, Applied Sciences Group, Health Sciences Authority, 11 Outram Road, 169078, Singapore. Electronic address: Kee_Chee_Leong@hsa.gov.sg.
authors.forename: Chee-Leong
authors.initials: CL
authors.lastname: Kee
authors.affiliation: Pharmaceutical Laboratory, Applied Sciences Group, Health Sciences Authority, 11 Outram Road, 169078, Singapore.
authors.forename: Min-Yong
authors.initials: MY
authors.lastname: Low
authors.affiliation: Pharmaceutical Laboratory, Applied Sciences Group, Health Sciences Authority, 11 Outram Road, 169078, Singapore.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Ge
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods; D019587:Dietary Supplements / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D000077489:Piperazine; D010879:Piperazines / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013457:Sulfur Compounds / Q000737:chemistry*
chemical_list: D010879:Piperazines; D013457:Sulfur Compounds; D000077489:Piperazine
keywords: 3,5-dimethylpiperazinyl dithio-desmethylcarbodenafil; Health supplement; Mass Spectrometry; NMR