title: Uncoupling between cerebral perfusion and oxygenation during incremental exercise in an athlete with postconcussion syndrome: a case report.
abstract: High-intensity exercise may pose a risk to patients with postconcussion syndrome (PCS) when symptomatic during exertion. The case of a paralympic athlete with PCS who experienced a succession of convulsion-awakening periods and reported a marked increase in postconcussion symptoms after undergoing a graded symptom-limited aerobic exercise protocol is presented. Potential mechanisms of cerebrovascular function failure are then discussed.
authors.affiliation: Department of Kinesiology, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada.|Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Quebec City, Quebec, Canada.
authors.forename: Sarah
authors.initials: S
authors.lastname: Imhoff
authors.affiliation: Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Quebec City, Quebec, Canada.|Pulmonary Hypertension Research Group, Quebec Heart and Lungs Institute Research Center, Laval University, Quebec City, Quebec, Canada.
authors.forename: Simon
authors.initials: S
authors.lastname: Malenfant
authors.affiliation: Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Quebec City, Quebec, Canada.
authors.forename: Éric
authors.initials: É
authors.lastname: Nadreau
authors.affiliation: Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Quebec City, Quebec, Canada.
authors.forename: Paul
authors.initials: P
authors.lastname: Poirier
authors.affiliation: Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, South Wales, United Kingdom.|Sondes Moléculaires en Biologie, Laboratoire Chimie Provence UMR 6264 CNRS, Université de Provence Marseille, Marseille, France.
authors.forename: Damian M
authors.initials: DM
authors.lastname: Bailey
authors.affiliation: Department of Kinesiology, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada patrice.brassard@kin.ulaval.ca.|Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Quebec City, Quebec, Canada.
authors.forename: Patrice
authors.identifier: http://orcid.org/0000-0002-6254-5044
authors.initials: P
authors.lastname: Brassard
mesh_terms: D000328:Adult; D062186:Arterial Pressure; D056352:Athletes; D001783:Blood Flow Velocity; D002540:Cerebral Cortex / Q000098:blood supply* / Q000503:physiopathology*; D015444:Exercise; D005260:Female; D006801:Humans; D020768:Middle Cerebral Artery / Q000503:physiopathology; D038223:Post-Concussion Syndrome / Q000503:physiopathology*; D012119:Respiration
keywords: Cerebral oxygenation; cerebral perfusion; exercise; postconcussion syndrome