title: Unprotected Left Main Disease and Percutaneous Intervention: A Prototype for Precision Medicine.
abstract: The SYNTAX Score based on angiographic findings is an actionable risk prediction model helping guide treatment for significant unprotected left main disease. Adding the clinical factor based EuroSCORE to SYNTAX improves outcome prediction for percutaneous coronary intervention of unprotected left main disease. Prediction models are an increasingly useful tool permitting cardiologists to optimize patient outcomes through "personalized" or precision medicine.
authors.affiliation: Cardiovascular Division, University of Alabama at Birmingham, Birmingham and Alabaster, Alabama.
authors.forename: Arka
authors.initials: A
authors.lastname: Chatterjee
authors.affiliation: Department of Biostatistics, University of Alabama at Birmingham, Birmingham and Alabaster, Alabama.|Heart South Cardiovascular Group, Birmingham and Alabaster, Alabama.
authors.forename: William B
authors.initials: WB
authors.lastname: Hillegass
mesh_terms: D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000628:therapy; D054855:Drug-Eluting Stents; D006801:Humans; D053208:Kaplan-Meier Estimate; D062645:Percutaneous Coronary Intervention; D057285:Precision Medicine; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome