title: Conductive Polymeric Ionic Liquid/Fe3O4Nanocomposite as an Efficient Catalyst for the Voltammetric Determination of Amlodipine Besylate.
abstract: A novel conductive polymeric ionic liquid (IL)-Fe3O4 nanocomposite (represented as PIL-Fe3O4) based on inorganic-organic hybrid material was synthesized using two different methods. Nuclear magnetic resonance, Fourier transform infrared, X-ray diffraction, and field emission scanning electron microscopy characterized the structures of IL, Fe3O4 nanoparticles, and PIL-Fe3O4. The electrochemical sensors based on PIL-Fe3O4-modified glassy carbon electrode were fabricated, and each of these nanocomposites was examined for the ability to determine amlodipine besylate (AMD). The electrochemical study of the modified electrodes, as well as its efficiency for the electro-oxidation of AMD, was described in 0.1 M phosphate-buffered solution (pH 7.0) using voltammetric methods. The results exhibit a linear dynamic range from 1 to 500 nM and a detection limit of 0.36 nM. Finally, the modified electrode was used for the determination of AMD in pharmaceutical and biological samples.
authors.affiliation: Shahid Bahonar University of Kerman, Faculty of Sciences, Department of Chemistry, Kerman, Iran.
authors.forename: Fariba
authors.initials: F
authors.lastname: Fathirad
authors.affiliation: Shahid Bahonar University of Kerman, Faculty of Sciences, Department of Chemistry, Kerman, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Mostafavi
authors.affiliation: Graduate University of Advanced Technology, Institute of Science and High Technology and Environmental Sciences, Department of Environment, Kerman, Iran.
authors.forename: Daryoush
authors.initials: D
authors.lastname: Afzali
mesh_terms: D017311:Amlodipine / Q000032:analysis*; D001565:Benzoates / Q000737:chemistry; D002384:Catalysis; D055664:Electrochemical Techniques; D004566:Electrodes; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008956:Models, Chemical; D053761:Nanocomposites / Q000737:chemistry*; D010084:Oxidation-Reduction; D011092:Polyethylene Glycols / Q000737:chemistry
chemical_list: D001565:Benzoates; D007093:Imidazoles; D052578:Ionic Liquids; D058185:Magnetite Nanoparticles; C450003:poly(ethylene glycol) methacrylate polymer; D017311:Amlodipine; D011092:Polyethylene Glycols; C028022:2-sulfobenzoic acid cyclic anhydride; C018100:1-methylimidazole