title: Low Norton Scale Score Predicts Worse Outcomes for Parkinson's Disease Patients Hospitalized Due to Infection.
abstract: Background:Parkinson's disease (PD) patients are prone to infections leading to hospitalization. We used the Norton Scale score (NSS) as a prognostic tool for these patients.Method:Retrospective analysis of consecutive PD patients, all had NSS appreciation upon admission. Analyses were made to establish the association between NSS upon admission, short-term, and long-term clinical outcomes.Results:Five hundred twenty-eight PD patients' records were reviewed, of which 81 were eligible for analysis. Patients who died during hospitalization had a significantly lower NSS (10.0 vs. 13.1,p= .026). Among surviving patients, those who were discharged to more intensive care facilities relative to their original place of arrival also had a significantly lower NSS (10.38 vs. 13.63,p= .0002). Lower NSS was found to increase the risk for 1-year mortality (odds ratio = 1.3; 95% confidence interval = [1.09, 1.56],p= .003).Conclusion:Lower NSS upon admission of PD patients, suffering from infection is associated with worse clinical outcomes.
authors.affiliation: Tel Aviv University, Israel.
authors.forename: Omer
authors.initials: O
authors.lastname: Segal
authors.affiliation: Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: Sharon
authors.initials: S
authors.lastname: Hassin-Baer
authors.affiliation: Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: Iris
authors.initials: I
authors.lastname: Kliers
authors.affiliation: St George's, University of London, UK.
authors.forename: Keren Shaked
authors.initials: KS
authors.lastname: Cale'
authors.affiliation: Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: Gad
authors.initials: G
authors.lastname: Segal
keywords: Norton; Parkinson’s disease; hospitalization; infection; mortality; prognosis