title: [Three Cases of Bleeding from Advanced Gastric Cancer during Chemotherapy Treated with Transcatheter Arterial Embolization(TAE)].
abstract: Case 1: An 71-year-old man underwent chemotherapy with S-1 plus trastuzumab to treat type 3 gastric cancer that was diagnosed as Stage IV tubular adenocarcinoma(T4b[Panc], N3, H0, CY1, P0, M1). For anemia and active bleeding from the tumor, transcatheter arterial embolization(TAE)was performed with metallic coils on the splenic artery. Infarction of the spleen and left pleural effusion were observed. Second-line paclitaxel(PTX)chemotherapy was administered 4 weeks after TAE. Case 2: An 76-year-old man underwent chemotherapy with S-1 plus cisplatin to treat type 3 gastric cancer that was diagnosed as Stage IV tubular adenocarcinoma(T4a, N3, H0, P1, M1). For anemia and active bleeding from the tumor, TAE with gelatin sponge(Serescure®)was performed on the left and right gastric artery. Radiotherapy(31 Gy)with S-1 was performed because TAE was not effective for bleeding. After chemoradiotherapy, nab-PTX was administered. Case 3: An 74- year-old man underwent second-line chemotherapy with nab-PTX to treat type 4 advanced gastric cancer that was diagnosed as Stage IV tubular adenocarcinoma(T4a, N3, H1, P0, M1). For progression of anemia due to tumor bleeding, TAE with gelatin sponge(Serescure®)was performed on the left gastric artery. TAE was effective, and he was discharged from the hospital. In 2 of 3 cases, hemostasis was achieved by TAE. Therefore, TAE is effective to decrease bleeding from gastric cancer during chemotherapy.
authors.affiliation: Dept. of Surgery, Sakai City Medical Center.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kimura
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Makari
authors.forename: Johta
authors.initials: J
authors.lastname: Mikami
authors.forename: Yoko
authors.initials: Y
authors.lastname: Hiraki
authors.forename: Shingo
authors.initials: S
authors.lastname: Sasamatsu
authors.forename: Genta
authors.initials: G
authors.lastname: Sawada
authors.forename: Shin
authors.initials: S
authors.lastname: Nakahira
authors.forename: Jun
authors.initials: J
authors.lastname: Yamamura
authors.forename: Shunji
authors.initials: S
authors.lastname: Kamigaki
authors.forename: Ken
authors.initials: K
authors.lastname: Nakata
authors.forename: Naoki
authors.initials: N
authors.lastname: Ikeda
authors.forename: Masaki
authors.initials: M
authors.lastname: Tsujie
authors.forename: Junya
authors.initials: J
authors.lastname: Fujita
authors.forename: Akihiro
authors.initials: A
authors.lastname: Kuriu
authors.forename: Hiroki
authors.initials: H
authors.lastname: Ohzato
mesh_terms: D000368:Aged; D004621:Embolization, Therapeutic; D017809:Fatal Outcome; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*