title: Seizure detection and neuromodulation: A summary of data presented at the XIII conference on new antiepileptic drug and devices (EILAT XIII).
abstract: The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII) took place in Madrid, Spain from June 26th to 29th 2016. For the first time, the last day of the conference focused solely on new medical devices and neuromodulation. The current article summarises the presentations of that day, focusing first on EEG- and ECG based methods and devices for seizure detection. These methodologies form the basis for novel cardiac-based methods of vagal nerve and responsive deep brain stimulation that rely on the prediction or early detection of seizures and that are also included in this article.
authors.affiliation: Institute for Drug Research, School of Pharmacy and David R. Bloom Centre for Pharmacy Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address: meirb@ekmd.huji.ac.il.
authors.forename: Meir
authors.initials: M
authors.lastname: Bialer
authors.affiliation: The National Center for Epilepsy, Sandvika, Oslo University Hospital, Oslo, Norway; Department of Pharmacology, Oslo University Hospital, Oslo, Norway.
authors.forename: Svein I
authors.initials: SI
authors.lastname: Johannessen
authors.affiliation: Department of Pharmaceutics, University of Washington, Seattle, WA, USA; Department of Neurological Surgery, University of Washington, Seattle, WA, USA.
authors.forename: René H
authors.initials: RH
authors.lastname: Levy
authors.affiliation: Division of Clinical and Experimental Pharmacology, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; C. Mondino National Neurological Institute, Pavia, Italy.
authors.forename: Emilio
authors.initials: E
authors.lastname: Perucca
authors.affiliation: Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
authors.forename: Torbjörn
authors.initials: T
authors.lastname: Tomson
authors.affiliation: Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, WA, USA.
authors.forename: H Steve
authors.initials: HS
authors.lastname: White
authors.affiliation: Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, United Kingdom.
authors.forename: Matthias J
authors.initials: MJ
authors.lastname: Koepp
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology / Q000627:therapeutic use; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D006321:Heart / Q000503:physiopathology; D006801:Humans; D012640:Seizures / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D013030:Spain
chemical_list: D000927:Anticonvulsants
keywords: Deep brain stimulation; ECG; EEG; Seizure detection; Vagal nerve stimulation