title: Laparoscopic radical cystectomy with novel orthotopic neobladder with bilateral isoperistaltic afferent limbs: initial experience.
abstract: OBJECTIVE
  To introduce a new method of constructing an orthotopic ileal neobladder with bilateral isoperistaltic afferent limbs, and to describe its clinical outcomes.
  
  
  METHODS
  From January 2012 to December 2013, 16 patients underwent a new method of orthotopic ileal neobladder after laparoscopic radical cystectomy for bladder cancer. To construct the neobladder, an ileal segment 60cm long was isolated approximately 25cm proximally to the ileocecum. The proximal 20cm of the ileal segment was divided into two parts for bilateral isoperistaltic afferent limbs. The proximal 10cm of the ileal segment was moved to the distal end of the ileal segment for the right isoperistaltic afferent limb, and the remaining proximal 10cm ileal segment was reserved for the left isoperistaltic afferent limb. The remaining length of the 40cm ileal segment was detubularized along its antimesenteric border to form a reservoir. The neobladder was sutured to achieve a spherical configuration.
  
  
  RESULTS
  All procedures were carried out successfully. The mean operative time was 330 min, mean blood loss was 328mL, and mean hospital stay was 12.5 days. The mean neobladder capacity 6 and 12 months after surgery was 300mL and 401mL, respectively. With a mean follow-up of 22.8 months, all patients achieved daytime continence and 15 achieved nighttime continence. The mean peak urinary flow rate was 11.9mL/s and 12.8mL/s at 6 and 12 months postoperatively, respectively.
  
  
  CONCLUSIONS
  This novel procedure is feasible, safe, simple to perform, and provides encouraging functional outcomes. However, comparative studies with long-term follow-up are required to prove its superiority.
authors.affiliation: Department of Urology Beijing Chao Yang Hospital, Affiliate of Capital Medical University, Beijing, Republic of China.
authors.forename: Nian-Zeng
authors.initials: NZ
authors.lastname: Xing
authors.affiliation: Department of Urology Beijing Chao Yang Hospital, Affiliate of Capital Medical University, Beijing, Republic of China.
authors.forename: Ning
authors.initials: N
authors.lastname: Kang
authors.affiliation: Department of Urology Beijing Chao Yang Hospital, Affiliate of Capital Medical University, Beijing, Republic of China.
authors.forename: Li-Mming
authors.initials: LM
authors.lastname: Song
authors.affiliation: Department of Urology Beijing Chao Yang Hospital, Affiliate of Capital Medical University, Beijing, Republic of China.
authors.forename: Yi-Nong
authors.initials: YN
authors.lastname: Niu
authors.affiliation: Department of Urology Beijing Chao Yang Hospital, Affiliate of Capital Medical University, Beijing, Republic of China.
authors.forename: Ming-Shuai
authors.initials: MS
authors.lastname: Wang
authors.affiliation: Department of Urology Beijing Chao Yang Hospital, Affiliate of Capital Medical University, Beijing, Republic of China.
authors.forename: Jun-Hui
authors.initials: JH
authors.lastname: Zhang
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000601:surgery*; D015653:Cystectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000601:surgery*; D010535:Laparoscopy / Q000379:methods*; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D019651:Plastic Surgery Procedures / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000000981:diagnostic imaging / Q000601:surgery*; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*
keywords: Cystectomy; Laparoscopy; Urinary Bladder Neoplasms; surgery [Subheading] 