title: Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS.
abstract: Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, IN, USA. cooks@purdue.edu.
authors.forename: V
authors.identifier: http://orcid.org/0000-0002-3924-6943
authors.initials: V
authors.lastname: Pirro
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, IN, USA. cooks@purdue.edu.
authors.forename: A K
authors.initials: AK
authors.lastname: Jarmusch
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, IN, USA. cooks@purdue.edu.
authors.forename: C M
authors.initials: CM
authors.lastname: Alfaro
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, USA. eyas.hattab@louisville.edu.
authors.forename: E M
authors.initials: EM
authors.lastname: Hattab
authors.affiliation: Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. acohenmd@gmail.com.
authors.forename: A A
authors.initials: AA
authors.lastname: Cohen-Gadol
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, IN, USA. cooks@purdue.edu.
authors.forename: R Graham
authors.initials: RG
authors.lastname: Cooks
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D021241:Spectrometry, Mass, Electrospray Ionization