title: Carbon Dioxide-Controlled Assembly of Water-Soluble Conjugated Polymers Catalyzed by Carbonic Anhydrase.
abstract: The CO2-responsive and biocatalytic assembly based on conjugated polymers has been demonstrated by combining the signal amplification property of the polythiophene derivative (PTP) and the catalytic actions of carbonic anhydrase (CA). CO2is applied as a new trigger mode to construct the smart assembly by controlling the electrostatic and hydrophobic interactions between the PTP molecules in aqueous solution, leading to the visible fluorescence changes. Importantly, the assembly transformation of PTP can be specifically and highly accelerated by CA based on the efficient catalytic activity of CA for the inter-conversion between CO2and HCO3-, mimicking the CO2-associated biological processes that occurred naturally in living organisms. Moreover, the PTP-based assembly can be applied for biomimetic CO2sequestration with fluorescence monitoring in the presence of CA and calcium.
authors.affiliation: School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Yuan
authors.affiliation: School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 300401, P. R. China.|Key Laboratory of Hebei Province for Molecular Biophysics, Institute of Biophysics, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Chengfen
authors.initials: C
authors.lastname: Xing
authors.affiliation: Key Laboratory of Hebei Province for Molecular Biophysics, Institute of Biophysics, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Yibing
authors.initials: Y
authors.lastname: Fan
authors.affiliation: School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Ran
authors.initials: R
authors.lastname: Chai
authors.affiliation: Key Laboratory of Hebei Province for Molecular Biophysics, Institute of Biophysics, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Ruimin
authors.initials: R
authors.lastname: Niu
authors.affiliation: School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhan
authors.affiliation: Key Laboratory of Hebei Province for Molecular Biophysics, Institute of Biophysics, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Fei
authors.initials: F
authors.lastname: Peng
authors.affiliation: Key Laboratory of Hebei Province for Molecular Biophysics, Institute of Biophysics, Hebei University of Technology, Tianjin, 300401, P. R. China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Qi
mesh_terms: D055162:Biocatalysis; D002245:Carbon Dioxide / Q000737:chemistry / Q000378:metabolism*; D024402:Carbonic Anhydrase II / Q000737:chemistry / Q000378:metabolism*; D010316:Particle Size; D011108:Polymers / Q000737:chemistry / Q000378:metabolism*; D012995:Solubility; D013499:Surface Properties; D014867:Water / Q000737:chemistry / Q000378:metabolism*
chemical_list: D011108:Polymers; D014867:Water; D002245:Carbon Dioxide; D024402:Carbonic Anhydrase II
keywords: CO2-responsive assembly; carbonic anhydrases; water-soluble conjugated polymers