title: [A Case of Curatively Resected Ascending Colon Cancer Invading the Duodenum after Neoadjuvant Chemotherapy].
abstract: A 64-year-old woman with anorexia and anemia was diagnosed with ascending colon cancer invading the duodenum. Considering the difficulty of curative resection, we first performed gastrojejunostomy and ileostomy. After surgery, the patient received FOLFIRI with cetuximab as neoadjuvant chemotherapy. After 9 courses of the regimen, enhanced computed tomography revealed shrinkage of the lesion, with the efficacy evaluated as a partial response. The patient underwent right hemico- lectomy and partial resection of the duodenum. The pathological diagnosis was pT3(SS), pN0(0/30), ly1, v1, pPM0, pDM0, pRM0, fStage II . On histopathological examination, the efficacy of chemotherapy was evaluated as Grade 1a. The patient received adjuvant chemotherapy with FOLFIRI and remains well without any evidence of recurrence more than 6 months after surgery.
authors.affiliation: Dept. of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Yachi
authors.forename: Akihiko
authors.initials: A
authors.lastname: Murata
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Nishikawa
authors.forename: Kenichi
authors.initials: K
authors.lastname: Takahashi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Morita
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hakamada
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D044682:Colon, Ascending / Q000473:pathology* / Q000601:surgery*; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D004386:Duodenum / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D014057:Tomography, X-Ray Computed