title: [Curative Resection for Chemorefractory Advanced Gastric Cancer with Pancreatic Invasion by Pancreatoduodenectomy - A Case Report].
abstract: A 37-year-old woman was diagnosed with advanced gastric cancer. Pancreatic invasion of the tumor and positive cytology from peritoneal washing was found on staging laparoscopy. The patient received chemotherapy consisting of S-1 and CDDP, but the tumor size increased after 5 courses. The patient then received 2 courses of second line chemotherapy consisting of biweekly CPT-11; however, the tumor progressed and caused stenosis of the stomach. After gastrojejunostomy for the stenosis, negative cytology of intraperitoneal lavage was found. The patient underwent pancreatoduodenectomy with right hemicolectomy and wedge resection of the portal vein as curative resection. The patient was alive without recurrence 10 months after the surgery.
authors.affiliation: Dept. of Gastroenterological Surgery, Osaka Police Hospital.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Koh
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kishi
authors.forename: Ryo
authors.initials: R
authors.lastname: Tsukada
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tanemura
authors.forename: Mitsuyoshi
authors.initials: M
authors.lastname: Tei
authors.forename: Toru
authors.initials: T
authors.lastname: Masuzawa
authors.forename: Yozo
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Kenta
authors.initials: K
authors.lastname: Furukawa
authors.forename: Mikako
authors.initials: M
authors.lastname: Ikehara
authors.forename: Hiroki
authors.initials: H
authors.lastname: Akamatsu
mesh_terms: D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D018450:Disease Progression; D004338:Drug Combinations; D005260:Female; D006801:Humans; D000077146:Irinotecan; D009361:Neoplasm Invasiveness; D010094:Oxonic Acid / Q000008:administration & dosage; D010179:Pancreas / Q000473:pathology* / Q000601:surgery; D016577:Pancreaticoduodenectomy; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D005641:Tegafur / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin