title: Evaluation of Mobile Phone Performance for Near-Infrared Fluorescence Imaging.
abstract: We have investigated the potential for contrast-enhanced near-infrared fluorescence imaging of tissue on a mobile phone platform. Charge-coupled device- and phone-based cameras were used to image molded and three-dimensional-printed tissue phantoms, and an ex vivo animal model. Quantitative and qualitative evaluations of image quality demonstrate the viability of this approach and elucidate variations in performance due to wavelength, pixel color, and image processing.
authors.affiliation: Center for Devices and Radiological HealthFood and Drug Administration.
authors.forename: Pejhman
authors.initials: P
authors.lastname: Ghassemi
authors.affiliation: Department of Electrical and Computer EngineeringUniversity of Maryland.
authors.forename: Bohan
authors.initials: B
authors.lastname: Wang
authors.affiliation: Center for Devices and Radiological HealthFood and Drug Administration.
authors.forename: Jianting
authors.initials: J
authors.lastname: Wang
authors.affiliation: Center for Devices and Radiological HealthFood and Drug Administration.
authors.forename: Quanzeng
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Fischell Department of BioengineeringUniversity of Maryland.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, USA.
authors.forename: T
authors.initials: T
authors.lastname: Joshua Pfefer
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D007259:Infrared Rays; D008029:Lighting / Q000295:instrumentation; D008856:Microscopy, Fluorescence / Q000379:methods*; D063731:Mobile Applications; D019047:Phantoms, Imaging; D010781:Photography / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D000068997:Smartphone; D014584:User-Computer Interface