title: Plants from Lamiaceae family as source of antifungal molecules in humane and veterinary medicine.
abstract: This work aimed to review the main plants of Lamiaceae family with activity against pathogenic fungi of medical and veterinary interest. Published studies in the main international databases between January 2002 and June 2016 showed that 55 botanical species belonging to 27 genus presented antifungal activity in different forms of extractions, mainly essential oils. Pathogenic fungi of Aspergillus spp., Candida spp., Malassezia spp., Cryptococcus spp., Sporothrix spp., Microsporum spp., Trichophyton spp. and Epidermophyton spp. genus were in vitro sensitive to several plants of Lamiaceae family. Chemical molecules isolated were described as promising use as antifungals in mycoses, highlighting estragole, 1,8-cineole, terpineol-4, γ-terpinene, among others. However, it should be alert to need of universal standardization in the laboratories tests with natural products.
authors.affiliation: Centro de Diagnóstico e Pesquisa em Micologia Veterinária, Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brazil. Electronic address: waller.stefanie@yahoo.com.br.
authors.forename: Stefanie Bressan
authors.initials: SB
authors.lastname: Waller
authors.affiliation: Departamento de Clínicas Veterinária, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brazil.
authors.forename: Marlete Brum
authors.initials: MB
authors.lastname: Cleff
authors.affiliation: Centro de Diagnóstico e Pesquisa em Micologia Veterinária, Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brazil.
authors.forename: Emanoele Figueiredo
authors.initials: EF
authors.lastname: Serra
authors.affiliation: Centro de Diagnóstico e Pesquisa em Micologia Veterinária, Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brazil.
authors.forename: Anna Luiza
authors.initials: AL
authors.lastname: Silva
authors.affiliation: Centro de Diagnóstico e Pesquisa em Micologia Veterinária, Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brazil.
authors.forename: Angelita Dos Reis
authors.initials: AD
authors.lastname: Gomes
authors.affiliation: Departamento de Farmacologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
authors.forename: João Roberto Braga
authors.initials: JR
authors.lastname: de Mello
authors.affiliation: Centro de Diagnóstico e Pesquisa em Micologia Veterinária, Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brazil.
authors.forename: Renata Osório
authors.initials: RO
authors.lastname: de Faria
authors.affiliation: Centro de Diagnóstico e Pesquisa em Micologia Veterinária, Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas (UFPEL), Pelotas, RS, Brazil.
authors.forename: Mário Carlos Araújo
authors.initials: MC
authors.lastname: Meireles
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D001688:Biological Products / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D005658:Fungi / Q000187:drug effects*; D019686:Lamiaceae / Q000737:chemistry*; D009181:Mycoses / Q000188:drug therapy* / Q000662:veterinary*; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D001688:Biological Products; D010936:Plant Extracts
keywords: Antifungal resistance; Essential oils; Extracts; Mycosis; Natural products