title: A Case of Olanzapine-Induced Fever.
abstract: Olanzapine, a frequently used second-generation antipsychotic, has rarely been implicated as a cause of drug-induced fever in the absence of neuroleptic malignant syndrome. We describe a patient who developed isolated fever following olanzapine monotherapy, which subsided after discontinuation of olanzapine. Blockade of dopaminergic receptors and elevated cytokines concentration are possible mechanisms of fever development during treatment with olanzapine. This case calls for attention to olanzapine-induced fever in clinical practice.
authors.affiliation: Drs. Yang, MD, Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei, Taiwan. Dr. Ying-Yeh Chen, MD, ScD, Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Cho-Hsiang
authors.initials: CH
authors.lastname: Yang
authors.affiliation: Drs. Yang, MD, Chen, MD, ScD, Taipei City Psychiatric Center, Taipei City Hospital, Taipei, Taiwan. Dr. Ying-Yeh Chen, MD, ScD, Institute of Public Health and Department of Public Health, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Ying-Yeh
authors.initials: YY
authors.lastname: Chen
keywords: cytokine; dopamine antagonism; fever; olanzapine