title: [Pancreatic Panniculitis in Patients with Chronic Pancreatitis: Case Report and Review of Literature].
abstract: Pancreatic panniculitis is a rare complication characterized by subcutaneous fat necrosis associated with pancreatic disease. It has been postulated that pancreatic panniculitis is caused by the systemic activity of pancreatic enzymes that lead to microcirculatory disturbances. We report a 41-year-old heavy alcoholic woman with pancreatic panniculitis that coexisted with acute and chronic pancreatitis. She was diagnosed with chronic pancreatitis and alcoholic liver cirrhosis 5 years ago. She presented with multiple, tender, erythematous, subcutaneous nodules with heat sensation on both lower legs. Laboratory evaluation revealed an increase in the serum blood amylase and lipase. Histopathologic findings showed fat necrosis with inflammation around the necrotic subcutaneous fat tissue. The lesions subsided gradually with an improvement of acute pancreatitis.
authors.affiliation: Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
authors.forename: Eui Joong
authors.initials: EJ
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
authors.forename: Min Su
authors.initials: MS
authors.lastname: Chu
authors.affiliation: Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
authors.forename: Ki Chang
authors.initials: KC
authors.lastname: Sohn
authors.affiliation: Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
authors.forename: Dong Ho
authors.initials: DH
authors.lastname: Cho
authors.affiliation: Department of Dermatology, Wonkwang University College of Medicine, Iksan, Korea.
authors.forename: Ga Hye
authors.initials: GH
authors.lastname: Na
authors.affiliation: Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
authors.forename: Haak Cheoul
authors.initials: HC
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Cho
mesh_terms: D000328:Adult; D000681:Amylases / Q000097:blood; D004890:Erythema / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007753:Laboratories; D008049:Lipase / Q000097:blood; D008104:Liver Cirrhosis, Alcoholic / Q000175:diagnosis / Q000473:pathology; D050500:Pancreatitis, Chronic / Q000150:complications / Q000473:pathology*; D015434:Panniculitis / Q000150:complications / Q000175:diagnosis*; D012867:Skin / Q000473:pathology
chemical_list: D008049:Lipase; D000681:Amylases
keywords: Chronic pancreatitis; Panniculitis; Subcutaneous fat necrosis