title: Galanin's implications for post-stroke improvement.
abstract: Stroke leads to a variety of pathophysiological conditions such as ischemic infarct, cerebral inflammation, neuronal damage, cognitive decline, and depression. Many endeavors have been tried to find the therapeutic solutions to attenuate severe neuropathogenesis after stroke. Several studies have reported that a decrease in the neuropeptide regulator 'galanin' is associated with neuronal loss, learning and memory dysfunctions, and depression following a stroke. The present review summarized recent evidences on the function and the therapeutic potential of galanin in post-ischemic stroke to provide a further understanding of galanin's role. Hence, we suggest that galanin needs to be considered as a therapeutic factor in the alleviation of post-stroke pathologies.
authors.affiliation: Department of Biomedical Sciences, Center for Creative Biomedical Scientists at Chonnam National University, Gwangju, Korea.; Human Life Research Center, Dong-A University, Busan, Korea.
authors.forename: Juhyun
authors.initials: J
authors.lastname: Song
authors.affiliation: Human Life Research Center, Dong-A University, Busan, Korea.; Department of Food Science and Nutrition, Dong-A University, Brain Busan 21, Busan, Korea.
authors.forename: Oh Yoen
authors.initials: OY
authors.lastname: Kim
keywords: Cognitive decline; Depression; Galanin; Inflammation; Post-stroke