title: Influence to high-intensity intermittent and moderate-intensity continuous exercise on indices of cardio-inflammatory health in men.
abstract: The aim of this study was to evaluate the influence to acute exercises performed in different intensities with volume equalized (5 km) on indices of cardio-inflammatory health. Twelve physically active male subjects (age, 23.22±5.47 years; height, 174.75±5.80 m; weight, 75.13±6.61 kg; maximal oxygen uptake, 52.92 mL/kg/min), after determination of peak oxygen uptake (VO2Peak) and the speed associated with VO2Peak(sVO2Peak), completed two randomly experimental trials: high-intensity intermittent exercise (HIIE: 1:1 at 100% sVO2Peak) and moderate-intensity continuous exercise (MICE: 70% sVO2Peak). Brain-derived neurotrophic factor (BDNF), adiponectin and plasminogen inhibitor-1 (PAI-1) data were analyzed pre, immediately, and 60 min after the exercise session. Statistical analysis comparisons between moments and between HIIE and MICE were performed using a mixed model and statistical and significance was set at <5%. PAI-1 presented an effect for time from pre to immediately after exercise moment (P<0.018) and from immediately to 60 min after exercise moment (P<0.001) only in MICE. BDNF presented an effect for time from pre to immediately after exercise to HIIE (P<0.022) and from immediately to 60 min after exercise to MICE (P<0.034). HIIE promotes BDNF increase and that there is negative correlation between PAI-1 concentrations and BDNF in both protocols in healthy sportsmen, favoring an anti-atherogenic profile.
authors.affiliation: Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, Brazil.
authors.forename: Carolina C
authors.initials: CC
authors.lastname: Santos
authors.affiliation: Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, Brazil.
authors.forename: Tiego A
authors.initials: TA
authors.lastname: Diniz
authors.affiliation: Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, Brazil.
authors.forename: Daniela S
authors.initials: DS
authors.lastname: Inoue
authors.affiliation: Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, Brazil.
authors.forename: José
authors.initials: J
authors.lastname: Gerosa-Neto
authors.affiliation: Department of Sport, School of Physical Education and Sport, University of São Paulo, São Paulo, Brasil.
authors.forename: Valéria L G
authors.initials: VL
authors.lastname: Panissa
authors.affiliation: Faculdade de Nutrição, Universidade Federal de Goiás. Goiânia, Brazil.
authors.forename: Gustavo Duarte
authors.initials: GD
authors.lastname: Pimentel
authors.affiliation: Department of Physical Education, Federal University of Pernambuco, Recife, Brazil.
authors.forename: Eduardo Z
authors.initials: EZ
authors.lastname: Campos
authors.affiliation: Exercise Physiology, Training and Training Therapy Research Group, Institute of Sport Science, University of Graz, Graz, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Hofmann
authors.affiliation: Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, Brazil.
authors.forename: Fábio S
authors.initials: FS
authors.lastname: Lira
keywords: Cardio-inflammatory health; Cytokines; High-intensity intermittent exercise; Moderate-intensity continuous exercise