title: Wunderlich's syndrome as a manifestation of polyarteritis nodosa.
abstract: Wunderlich syndrome is a rare clinical entity characterised by spontaneous renal haemorrhage that can be life-threatening and requires emergency attention. The most frequent aetiologies are renal tumours and vascular diseases. The authors report a case of a patient admitted with hypovolaemic shock due to a retroperitoneal haematoma in the context of polyarteritis nodosa (PAN). Prognosis of untreated PAN is very poor with 13% 5-year survival rate. Therefore, early recognition of disease and proper treatment with immunosuppressors will prevent catastrophic complications and improves survival.
authors.affiliation: Department of Internal Medicine, Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Pedro
authors.initials: P
authors.lastname: Beirão
authors.affiliation: Department of Rheumatology, Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Lídia
authors.initials: L
authors.lastname: Teixeira
authors.affiliation: Department of Internal Medicine, Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Pereira
authors.affiliation: Department of Internal Medicine, Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Margarida Lopes
authors.initials: ML
authors.lastname: Coelho
mesh_terms: D000783:Aneurysm / Q000000981:diagnostic imaging; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006406:Hematoma / Q000000981:diagnostic imaging / Q000209:etiology*; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D012077:Renal Artery / Q000000981:diagnostic imaging; D012187:Retroperitoneal Space / Q000000981:diagnostic imaging; D012769:Shock / Q000175:diagnosis / Q000209:etiology*; D013577:Syndrome; D014057:Tomography, X-Ray Computed
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone