title: Sleep disturbances in individuals at clinical high risk for psychosis.
abstract: There has been recent interest in understanding the role that sleep disturbance plays in patients at Clinical High Risk for psychosis (CHR). We assessed sleep disturbance in 194 CHR patients and 66 healthy control subjects and their relationship to symptoms (positive, negative and general functioning). Patients experienced significantly more sleep disturbance than healthy control subjects and their sleep disturbance was related to greater positive and negative symptoms and worse overall functioning. Targeting sleep disturbance in CHR individuals may provide alternative means of treating the CHR syndrome.
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA. Electronic address: slcp118@me.com.
authors.forename: Sarah-Lucy
authors.initials: SL
authors.lastname: Poe
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Gary
authors.initials: G
authors.lastname: Brucato
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Nicolina
authors.initials: N
authors.lastname: Bruno
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Leigh Y
authors.initials: LY
authors.lastname: Arndt
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Shelly
authors.initials: S
authors.lastname: Ben-David
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Kelly E
authors.initials: KE
authors.lastname: Gill
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Tiziano
authors.initials: T
authors.lastname: Colibazzi
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Joshua T
authors.initials: JT
authors.lastname: Kantrowitz
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Cheryl M
authors.initials: CM
authors.lastname: Corcoran
authors.affiliation: Columbia University Medical Center, Department of Psychiatry, New York, NY, USA; The New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Ragy R
authors.initials: RR
authors.lastname: Girgis
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D062706:Prodromal Symptoms; D011618:Psychotic Disorders / Q000175:diagnosis*; D012306:Risk; D012893:Sleep Wake Disorders / Q000175:diagnosis*; D055815:Young Adult
keywords: Clinical/Ultra high risk; Prodromal; Psychosis; Sleep Disturbance