title: [Comparing the activity of multiple sclerosis (MS) at the minute and at 20 minutes of gadolinium application in magnetic resonance imaging (MRI) of the brain?]
abstract: The aim was to compare active disease in patients diagnosed with multiple sclerosis, brain by MRI after gadolinium application at one minute and 20 minutes. A longitudinal, prospective, observational, analytical and comparative study was conducted in 18 patients over 18 years of age diagnosed with multiple sclerosis (MS). An analysis was made for each patient, watching for inflammatory activity in MS lesions, comparing the results to one minute and 20 minutes after the application of gadolinium. For the descriptive analysis, absolute frequencies and percentages were used, as well as means and standard deviations or medians with ranges for the inferential analysis comparing the presence or absence of enhancement in lesions at one minute and 20 minutes; the exact probability test used was Fisher. Finally, the results were analyzed, looking at the gender distribution: 14 (77.8%) were female. The average age was 36.2 ± 9.5 years, with a minimum age of 18 years and a maximum of 55 years; four patients (22.2%) presented further highlight active lesions at 20 minutes, and two patients (11.1%) presented enhancement at one minute. Concluding that MRI in the diagnosis of MS is very important for the detection of activity in lesions caused by the disease, it is evident that the optimum time for evaluation of postcontrast sequences is 20 minutes.
authors.affiliation: Departamento de Radiología e Imagen, UMAE No. 25, IMSS, Monterrey, N.L., México.
authors.forename: Christina
authors.initials: C
authors.lastname: Saldívar-Uribe
authors.affiliation: Departamento de Radiología e Imagen, UMAE No. 25, IMSS, Monterrey, N.L., México.
authors.forename: Mario Alberto
authors.initials: MA
authors.lastname: de la Portilla-Villanueva
authors.affiliation: Departamento de Radiología e Imagen, UMAE No. 25, IMSS, Monterrey, N.L., México.
authors.forename: Alberto
authors.initials: A
authors.lastname: Esau-Mendoza-García
mesh_terms: D000293:Adolescent; D000328:Adult; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D005682:Gadolinium / Q000008:administration & dosage*; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011446:Prospective Studies; D013997:Time Factors; D055815:Young Adult
chemical_list: D003287:Contrast Media; D005682:Gadolinium