title: Reduction in retained activity participation is associated with depressive symptoms 3 months after mild stroke: An observational cohort study.
abstract: OBJECTIVE
  To quantify the association of depressive symptoms with retained activity participation 3 months post-stroke, after adjusting for neurological stroke severity and age.
  
  
  METHODS
  A cross-sectional observational study of retained activity participation and depressive symptoms in stroke survivors with ischaemic stroke.
  
  
  METHODS
  One hundred stroke survivors with mild neurological stroke severity.
  
  
  METHODS
  One hundred stroke survivors were recruited from 5 metropolitan hospitals and reviewed at 3 months post-stroke using measures of activity participation, Activity Card Sort-Australia, and depressive symptoms, Montgomery-Asberg Depression Rating Scale Structured Interview Guide (MADRS-SIGMA).
  
  
  RESULTS
  The median percentage of retained overall activity participation was 97%, (interquartile range 79-100%). Using multiple median regression, 1 point increase in the MADRS-SIGMA was associated with a median decrease of 0.7% (95% CI -1.4 to -0.1, p=0.02) of retained overall activity participation, assuming similar neurological stroke severity and age.
  
  
  CONCLUSIONS
  The findings of this study establish the association of depressive symptoms with retained activity participation 3 months post-stroke in stroke survivors with mild neurological stroke severity. Clinical rehabilitation recommendations to enhance activity participation need to account for those with even mild depressive symptoms post-stroke.
authors.affiliation: Occupational Therapy, Department of Community and Clinical Allied Health, School of Allied Health, La Trobe University and Neurorehabilitation and Recovery, Stroke Division, The Florey Institute of Neuroscience and Mental Health, 3084 Heidelberg, Australia. tamara.tse@florey.edu.au.
authors.forename: Tamara
authors.initials: T
authors.lastname: Tse
authors.forename: Jacinta
authors.initials: J
authors.lastname: Douglas
authors.forename: Primrose
authors.initials: P
authors.lastname: Lentin
authors.forename: Thomas
authors.initials: T
authors.lastname: Lindén
authors.forename: Leonid
authors.initials: L
authors.lastname: Churilov
authors.forename: Henry
authors.initials: H
authors.lastname: Ma
authors.forename: Stephen
authors.initials: S
authors.lastname: Davis
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Donnan
authors.forename: Leeanne M
authors.initials: LM
authors.lastname: Carey
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D020521:Stroke / Q000401:mortality / Q000523:psychology*; D017741:Survivors; D013997:Time Factors