title: [A Case of Male Hereditary Breast Cancer Involving a Sentinel Lymph Node Biopsy].
abstract: We report a rare case of male hereditary breast cancer in which a sentinel lymph node biopsy was performed. A 62-yearold man was admitted to our hospital because of a palpable tumor in his right breast. Both his younger sister and daughter had had breast cancer. Genetic testing revealed a morbid mutation in the BRCA2 gene. The tumor was palpated to an elastic hard mass and had a clear border in the right DCE area. We performed a core needle biopsy and diagnosed invasive ductal carcinoma, specifically, cT1cN0cM0, cStage I hereditary breast cancer. The patient underwent mastectomy and a sentinel lymph node biopsy. Nine days later, tamoxifen therapy was initiated. There has been no sign of recurrence during the 9 months after the operation.
authors.affiliation: Dept. of Digestive Surgery, Tsushimi Hospital.
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Tokunou
authors.forename: Tatsuhito
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Hisato
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Ryoji
authors.initials: R
authors.lastname: Kamei
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kitamura
authors.forename: Seiichirou
authors.initials: S
authors.lastname: Ando
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D024682:BRCA2 Protein / Q000235:genetics; D001943:Breast Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D018567:Breast Neoplasms, Male / Q000188:drug therapy / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009154:Mutation; D021701:Sentinel Lymph Node Biopsy; D013629:Tamoxifen / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D018931:Antineoplastic Agents, Hormonal; D024682:BRCA2 Protein; C551750:BRCA2 protein, human; D013629:Tamoxifen