title: STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease.
abstract: BACKGROUND
  The Stroke and Cognition consortium (STROKOG) aims to facilitate a better understanding of the determinants of vascular contributions to cognitive disorders and help improve the diagnosis and treatment of vascular cognitive disorders (VCD).
  
  
  METHODS
  Longitudinal studies with ≥75 participants who had suffered or were at risk of stroke or TIA and which evaluated cognitive function were invited to join STROKOG. The consortium will facilitate projects investigating rates and patterns of cognitive decline, risk factors for VCD, and biomarkers of vascular dementia.
  
  
  RESULTS
  Currently, STROKOG includes 25 (21 published) studies, with 12,092 participants from five continents. The duration of follow-up ranges from 3 months to 21 years.
  
  
  CONCLUSIONS
  Although data harmonization will be a key challenge, STROKOG is in a unique position to reuse and combine international cohort data and fully explore patient level characteristics and outcomes. STROKOG could potentially transform our understanding of VCD and have a worldwide impact on promoting better vascular cognitive outcomes.
authors.affiliation: Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, Australia; Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia.
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authors.affiliation: Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, Australia.
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authors.affiliation: Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, Australia.
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authors.lastname: Crawford
authors.affiliation: Department of Psychology, Royal College of Surgeons in Ireland, Dublin, Ireland.
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authors.lastname: Mellon
authors.affiliation: Department of Psychology, Royal College of Surgeons in Ireland, Dublin, Ireland.
authors.forename: Anne
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authors.lastname: Hickey
authors.affiliation: Department of Stroke and Geriatric Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
authors.forename: David
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authors.lastname: Williams
authors.affiliation: University of Lille, Inserm, CHU Lille, U1171 - Degenerative & Vascular Cognitive Disorders, Lille, France.
authors.forename: Régis
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authors.lastname: Bordet
authors.affiliation: University of Lille, Inserm, CHU Lille, U1171 - Degenerative & Vascular Cognitive Disorders, Lille, France.
authors.forename: Anne-Marie
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authors.lastname: Mendyk
authors.affiliation: University of Lille, Inserm, CHU Lille, CIC 1403 - Centre d'investigation clinique, Lille, France.
authors.forename: Patrick
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authors.affiliation: University of Lille, Inserm, CHU Lille, CIC 1403 - Centre d'investigation clinique, Lille, France.
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authors.affiliation: Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
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authors.affiliation: Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
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authors.affiliation: Florey Institute for Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
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authors.affiliation: Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, Australia; Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia; Memory Ageing and Cognition Center, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Medicine (Neurology Division), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Yan-Hong
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authors.affiliation: Memory Ageing and Cognition Center, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Medicine (Neurology Division), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
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authors.affiliation: Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.
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authors.affiliation: Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
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authors.affiliation: Cognitive Neurology and Stroke Programs, University of Central Florida, Orlando VA Medical Center, Orlando, Florida, USA.
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authors.affiliation: University of Lille, Inserm, CHU Lille, U1171 - Degenerative & Vascular Cognitive Disorders, Lille, France.
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authors.affiliation: University of Lille, Inserm, CHU Lille, U1171 - Degenerative & Vascular Cognitive Disorders, Lille, France.
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authors.affiliation: Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, Australia.
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keywords: Cohort studies; Data harmonization; International consortium; Post-stroke dementia; Small vessel disease; Vascular cognitive disorder; Vascular dementia