title: [Matrix metalloproteinase in development, physiology and degenerative processes of skeletal muscles].
abstract: Matrix metalloproteinase (MMP) are a large family of enzymes, active in both physiological and pathological processes of many tissues. These proteases are able to selectively degrade components of the Extracellular Matrix (ECM). In skeletal muscle enzymes included in the MMP family are involved in tissue remodeling process, playing a key role in myogenesis as well as in tissue remodeling and regeneration of muscle. This paper describes the role of this group of enzymes in the conversion of skeletal muscle extracellular environment both in physiological processes in skeletal muscle and in the context of regeneration of the tissue.
authors.affiliation: Department of Cytology, Institute of Zoology, Faculty of Biology, University of Warsaw, 1 Miecznikowa St., 02-096 Warsaw, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Jung
authors.affiliation: Department of Cytology, Institute of Zoology, Faculty of Biology, University of Warsaw, 1 Miecznikowa St., 02-096 Warsaw, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Zimowska
mesh_terms: D000818:Animals; D006801:Humans; D020782:Matrix Metalloproteinases / Q000378:metabolism / Q000502:physiology*; D018482:Muscle, Skeletal / Q000201:enzymology* / Q000254:growth & development / Q000502:physiology; D012038:Regeneration
chemical_list: D020782:Matrix Metalloproteinases
keywords: MMP; regeneration; skeletal muscle