title: Distribution of Malassezia Species in Patients with Different Dermatological Disorders and Healthy Individuals.
abstract: There are differences with respect to the commonly isolated Malassezia species, not only between healthy individuals and the patients with various skin diseases, but also between different countries. We investigated the species composition of Malassezia microflora on the skin of patients with Malassezia-associated diseases and of healthy subjects (HS). Two hundred and fifty skin scrapings from patients with pityriasis versicolor (PV), seborrheic dermatitis (SD), atopic dermatitis (AD), psoriasis (PS), and healthy subjects (HS), fifty each, were inoculated into Sabouraud dextrose agar and into modified Dixon agar and identified using conventional culture-based methods. In PV and PS lesions, the most common species was M. globosa (62% and 52%, respectively), while M. restricta was predominant in SD lesions (28%). M. sympodialis was the most common species recovered from AD (52%) and healthy trunk skin (30%). Fewer cultures were positive for Malassezia growth in patients with AD than in patients with other skin conditions, and even in controls. Our data are in agreement with other studies and suggest that the pathogenic species of PV is M. globosa. The evidence that any given species is clinically important in the pathogenicity of SD, AD and PS is still lacking.
authors.affiliation: Professor Asja Prohić, MD, PhD, Department of Dermatovenerology, University Clinical Center of Sarajevo, Bolnicka 25, 71000 Sarajevo, Bosnia and Herzegovina; asjaprohic@hotmail.com.
authors.forename: Asja
authors.initials: A
authors.lastname: Prohić
authors.forename: Tamara
authors.initials: T
authors.lastname: Jovović Sadiković
authors.forename: Suada
authors.initials: S
authors.lastname: Kuskunović-Vlahovljak
authors.forename: Rusmir
authors.initials: R
authors.lastname: Baljić
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002648:Child; D015897:Comorbidity; D016208:Databases, Factual; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000453:epidemiology; D012628:Dermatitis, Seborrheic / Q000175:diagnosis / Q000453:epidemiology; D003881:Dermatomycoses / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D038622:Internationality; D008290:Malassezia / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011565:Psoriasis / Q000175:diagnosis / Q000453:epidemiology; D012016:Reference Values; D018570:Risk Assessment; D017678:Sex Distribution; D014010:Tinea Versicolor / Q000175:diagnosis / Q000453:epidemiology; D055815:Young Adult