title: 68Ga-Exendin-4 PET/CT in Evaluation of Endoscopic Ultrasound-Guided Ethanol Ablation of an Insulinoma.
abstract: A 32-year-old man with endogenous hyperinsulinemic hypoglycemia was clinically diagnosed with an insulinoma. Conventional imaging result was negative, and a previous exploratory laparotomy with distal pancreatectomy failed to detect the tumor. Ga-exendin-4 PET/CT showed a lesion with intense radioactivity in the head of the pancreas suggestive of an insulinoma, and endoscopic ultrasound-guided ethanol ablation was performed. Postablation evaluation with Ga-exendin-4 PET/CT showed markedly decreased radioactivity of the tumor. The symptoms and blood glucose monitoring also suggested partial response of the insulinoma.
authors.affiliation: From the Departments of *Nuclear Medicine, †Gastroenterology, and ‡Endocrinology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Luo
authors.forename: Ji
authors.initials: J
authors.lastname: Li
authors.forename: Aiming
authors.initials: A
authors.lastname: Yang
authors.forename: Hongbo
authors.initials: H
authors.lastname: Yang
authors.forename: Fang
authors.initials: F
authors.lastname: Li
mesh_terms: D000328:Adult; D002425:Cautery / Q000009:adverse effects*; D056831:Coordination Complexes; D000431:Ethanol; D006801:Humans; D007340:Insulinoma / Q000000981:diagnostic imaging* / Q000601:surgery; D008297:Male; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D010455:Peptides; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals; D025321:Surgery, Computer-Assisted / Q000009:adverse effects
chemical_list: C000612060:68Ga-NOTA-exendin-4; D056831:Coordination Complexes; D010455:Peptides; D019275:Radiopharmaceuticals; D000431:Ethanol