title: The Systems Biology of Auxin in Developing Embryos.
abstract: Systems biology orientates signaling pathways in their biological context. This aim invariably requires models that ignore extraneous factors and focus on the most crucial pathways of any given process. The developing embryo encapsulates many important processes in plant development; understanding their interaction will be key to designing crops able to maximize yield in an ever-more challenging world. Here, we briefly summarize the role of auxin during embryo development. We highlight recent advances in our understanding of auxin signaling and discuss implications for a systems understanding of development.
authors.affiliation: Institute of Cytology and Genetics, Novosibirsk, 630090, Russia; Novosibirsk State University, Novosibirsk, 630090, Russia.
authors.forename: Victoria
authors.initials: V
authors.lastname: Mironova
authors.affiliation: Institute of Biology II, University of Freiburg, Schänzlestrasse 1, 79104 Freiburg, Germany.
authors.forename: William
authors.initials: W
authors.lastname: Teale
authors.affiliation: Institute of Biology II, University of Freiburg, Schänzlestrasse 1, 79104 Freiburg, Germany.
authors.forename: Mojgan
authors.initials: M
authors.lastname: Shahriari
authors.affiliation: Department of Physics, Syracuse University, Syracuse, NY 13210, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Dawson
authors.affiliation: Institute of Biology II, University of Freiburg, Schänzlestrasse 1, 79104 Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, Albert-Ludwigs-University of Freiburg, Freiburg 79104, Germany; Freiburg Institute of Advanced Sciences (FRIAS), Albert-Ludwigs-University of Freiburg, Freiburg79104, Germany. Electronic address: klaus.palme@biologie.uni-freiburg.de.
authors.forename: Klaus
authors.initials: K
authors.lastname: Palme
mesh_terms: D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000378:metabolism*; D008962:Models, Theoretical; D012639:Seeds / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D049490:Systems Biology / Q000379:methods*
chemical_list: D007210:Indoleacetic Acids
keywords: ARF; Aux/IAA; embryo patterning; mathematical model