title: [Candida infiltrations in the iris and lens during iritis and situation after sepsis].
abstract: Intraocular Candida infections are overall rather rare; nevertheless they are often found as endogenous infections after Candida sepsis and can be sight-threatening. The most common manifestations are either a sole chorioretinitis or an endophthalmitis. Here we report the case of a 35-year-old man developing Candida infiltrations in the lens capsule and behind the iris after corticosteroid treatment of a presumed HLA-B27-positive iritis. The patient suffered from a life-threatening intensive care stay with positive Candida blood cultures earlier after intestinal perforation. With systemic intracameral and topical voriconazole, the infection was successfully treated. In patients with positive blood samples for Candida, topical and systemic corticosteroids should be given with care even months after the last positive blood cultures.
authors.affiliation: Klinik für Augenheilkunde, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland. dkuerten@ukaachen.de.
authors.forename: D
authors.initials: D
authors.lastname: Kuerten
authors.affiliation: Klinik für Augenheilkunde, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Fuest
authors.affiliation: Klinik für Augenheilkunde, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Mazinani
authors.affiliation: Klinik für Augenheilkunde, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Walter
authors.affiliation: Klinik für Augenheilkunde, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
authors.forename: N
authors.initials: N
authors.lastname: Plange
mesh_terms: D000328:Adult; D000935:Antifungal Agents; D002175:Candida; D002177:Candidiasis; D009877:Endophthalmitis; D015821:Eye Infections, Fungal; D006801:Humans; D007498:Iris; D007500:Iritis; D008297:Male; D018805:Sepsis
chemical_list: D000935:Antifungal Agents
keywords: Infiltrates; Iritis; Ocular candidiasis; Ocular mycosis