title: [Pathological Complete Response in 3 Patients with Esophageal Cancer Treated with Neoadjuvant Chemoradiation Therapy].
abstract: Neoadjuvant chemotherapy(NAC)for esophageal cancer is standard in Japan. However, the value of neoadjuvant chemoradiation therapy(NACRT)is unknown. Thirteen patients with cStage II and III squamous cell carcinoma of the esopha- gus were treated with NACRT(CDDP 70mg/m2/day on day 1, 5-FU 70 mg/m2/day on days 1-4, radiation 30 Gy/15 Fr). We report 3 pathological CR cases and 10 non-CR cases of esophageal cancer. Between the CR and non-CR group there was no difference in the incidence of postoperative complications. No serious adverse events were observed. There were no significant differences in OS and RFS. Five cases relapsed in the non-CR group. There were no relapsed cases in the CR group.
authors.affiliation: Dept. of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center.
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Makuuchi
authors.forename: Sou
authors.initials: S
authors.lastname: Katayanagi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Osakabe
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Shigoka
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Sumi
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Kawachi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D059248:Chemoradiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D004938:Esophageal Neoplasms / Q000628:therapy*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D011379:Prognosis
chemical_list: D002945:Cisplatin; D005472:Fluorouracil