title: [CLINICAL EVALUATION OF THE NEW ANTISEPTIC MESHES].
abstract: Improving the results of hernia treatment and prevention of complications became a goal of our research which included two parts - experimental and clinical. Histomorphological and bacteriological researches showed that the best result out of the 3 control groups was received in case of covering implant "Coladerm"+ with chlorhexidine. Based on the experiment results working process continued in clinics in order to test and introduce new "coladerm"+ chlorhexidine covered poliprophilene meshes into practice. For clinical illustration there were 60 patients introduced to the research who had hernioplasty procedures by different nets: I group - standard meshes+"coladerm"+chlorhexidine, 35 patients; II group - standard meshes +"coladerm", 15 patients; III group - standard meshes, 10 patients. Assessment of the wound and echo-control was done post-surgery on the 8th, 30th and 90th days. This clinical research based on the experimental results once again showed the best anti-microbe features of new antiseptic polymeric biocomposite meshes (standard meshes+"coladerm"+chlorhexidine); timely termination of regeneration and reparation processes without any post-surgery suppurative complications. We hope that new antiseptic polymeric biocomposite meshes presented by us will be successfully used in surgical practice of hernia treatment based on and supported by expermental-clinical research.
authors.affiliation: I. Javakhishvili Tbilisi State Universiti, Medical Department, Faculty of Medicine; "A. Aladashvili Klinik", LTD; New Vision University Hospital; Tbilisi State Medical University, Department of Surgical Propedevtic, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Gogoladze
authors.affiliation: I. Javakhishvili Tbilisi State Universiti, Medical Department, Faculty of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Kiladze
authors.affiliation: I. Javakhishvili Tbilisi State Universiti, Medical Department, Faculty of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Chkhikvadze
authors.affiliation: I. Javakhishvili Tbilisi State Universiti, Medical Department, Faculty of Medicine.
authors.forename: D
authors.initials: D
authors.lastname: Jiqia
mesh_terms: D000328:Adult; D000818:Animals; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000627:therapeutic use*; D005260:Female; D059685:Herniorrhaphy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009757:Nylons; D011126:Polypropylenes; D011183:Postoperative Complications / Q000209:etiology; D011817:Rabbits; D013526:Surgical Mesh / Q000009:adverse effects
chemical_list: D000891:Anti-Infective Agents, Local; D009757:Nylons; D011126:Polypropylenes; D002710:Chlorhexidine