title: Pulmonary benign metastasizing leiomyoma presented as acute respiratory distress.
abstract: Benign metastasizing leiomyoma (BML) is a very rare condition and is characterized by the presence of benign smooth muscle tumours in organs distant from the uterus, most commonly the lung. It generally affects women of reproductive age and prognostic is usually excellent. However, the course of the disease is unpredictable. We report here the case of a 76-year-old woman with a previous medical history of uterine benign leiomyomas in whom BML was acutely revealed by a respiratory distress due to voluminous pulmonary and pleural leiomyomas requiring surgical extraction. Clinical evolution was remarkable by resistance to medical treatment and development of rare bone localization. BML is a contradictory entity characterized by benign histological features but with metastatic potential. Pulmonologists as well as oncologists in charge of patients with multiple pulmonary nodules and a history of uterine leiomyoma should be aware of this potential diagnosis in order to implement appropriate diagnostic procedures for this benign tumour.
authors.affiliation: Université Paris Descartes Sorbonne Paris Cité and AP-HP Paris France; Service de Pneumologie Hôpital Européen Georges Pompidou Paris France.
authors.forename: Jean
authors.initials: J
authors.lastname: Pastré
authors.affiliation: Service de Pneumologie Hôpital Européen Georges Pompidou Paris France.
authors.forename: Karine
authors.initials: K
authors.lastname: Juvin
authors.affiliation: Service de Chirurgie Thoracique Hôpital Européen Georges Pompidou Paris France.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Grand
authors.affiliation: Service d'Anatomo-pathologie Hôpital Européen Georges Pompidou Paris France.
authors.forename: Laure
authors.initials: L
authors.lastname: Gibault
authors.affiliation: Service de Pneumologie Hôpital Européen Georges Pompidou Paris France.
authors.forename: Judith
authors.initials: J
authors.lastname: Valcke
authors.affiliation: Université Paris Descartes Sorbonne Paris Cité and AP-HP Paris France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Israël-Biet
keywords: Benign metastasizing leiomyoma; lung; metastases; pleura