title: [A Case of Gastric Cancer Responding to Neoadjuvant Chemotherapy Leading to Histological Change to Grade 3].
abstract: A 70-year-old man with cStage III A(cT3N2H0P0CYXM0)advanced gastric cancer in the lesser curvature with esophageal invasion and bulky lymph nodes was treated with S-1/CDDP. After 4 courses of chemotherapy, the tumor and lymph nodes were found to be reduced in a CT examination. Total gastrectomy with lymph node dissection(D2)was performed. Histopathological examination revealed no cancer cells in the stomach or lymph nodes, indicating Grade 3.
authors.affiliation: Dept. of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Osakabe
authors.forename: So
authors.initials: S
authors.lastname: Katayanagi
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Makuuchi
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Shigoka
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Sumi
authors.forename: Akihiko
authors.initials: A
authors.lastname: Tsuchida
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Kawachi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D020360:Neoadjuvant Therapy; D060787:Neoplasm Grading; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin