title: Challenges in neurologic prognostication after neonatal brain injury.
abstract: Parents often ask neonatologists and neurologists to determine neurologic prognosis in the preterm and term infant after neonatal brain injury. Prognostication in these populations remains rather full of uncertainties. Knowledge of available diagnostic tests and their limitations allows the clinician to synthesize the most likely outcomes after neurologic injury. In this review, we describe the diagnostic tools available to the clinician, active areas of research, and challenges in neurologic prognostication of the neonate.
authors.affiliation: Department of Neurology, University of Washington, Seattle Children׳s Hospital, Seattle, WA.
authors.forename: Niranjana
authors.initials: N
authors.lastname: Natarajan
authors.affiliation: Division of Neurology, Ann & Robert H. Lurie Children׳s Hospital of Chicago, Northwestern University Feinberg School of Medicine, 225 E. Chicago Ave, Box #51, Chicago, IL 60611. Electronic address: apardo@luriechildrens.org.
authors.forename: Andrea C
authors.initials: AC
authors.lastname: Pardo
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001926:Brain Death / Q000175:diagnosis; D003142:Communication; D004453:Echoencephalography; D004569:Electroencephalography; D005071:Evoked Potentials; D005544:Forecasting; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000000981:diagnostic imaging / Q000503:physiopathology*; D007231:Infant, Newborn; D007234:Infant, Premature; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D011368:Professional-Family Relations; D011379:Prognosis; D019265:Spectroscopy, Near-Infrared; D013727:Terminal Care
chemical_list: D015415:Biomarkers
keywords: Brain Injury; Hypoxic ischemic encephalopathy; Prematurity; Prognostication