title: A Quality Improvement Initiative to Improve Patient Adherence to Vitamin Supplementation in Cystic Fibrosis.
abstract: Patients with cystic fibrosis (CF) and pancreatic insufficiency are prescribed fat-soluble vitamins, although compliance remains low. Our objective was to identify patient and caregiver knowledge deficits regarding vitamin supplementation, provide targeted education, and examine serum vitamin levels pre-and posteducation.
  
  
  
  This prospective quality improvement study involved 118 patients. A vitamin knowledge survey was given to patients/caregivers during a clinic visit, education was provided targeting knowledge deficits, and the survey was re-administered at the next clinic visit. Serum vitamin levels were collected at pre- and postsurvey.
  
  
  
  Results showed significant pre-post increases for patient and caregiver knowledge scores, and significant decreases in self-reported nonadherence to vitamin use and number of reported barriers affecting adherence. A significant change in vitamin E level to therapeutic range post-education was demonstrated.
  
  
  
  Our brief, targeted educational interventions regarding vitamin supplementation showed utility in a routine clinic setting.
authors.affiliation: *Department of Pharmacy, WVUMedicine†Department of Psychology, West Virginia University, Morgantown‡Départ. de Psychologies et Cliniques des Systèmes humains, Université de Liegè, Belgium§Department of Pediatrics, West Virginia University, Morgantown.
authors.forename: Lisa
authors.initials: L
authors.lastname: Garavaglia
authors.forename: Christina
authors.initials: C
authors.lastname: Duncan
authors.forename: Malorie
authors.initials: M
authors.lastname: Toucheque
authors.forename: Allilene
authors.initials: A
authors.lastname: Farley
authors.forename: Kathryn S
authors.initials: KS
authors.lastname: Moffett
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000097:blood / Q000188:drug therapy*; D019587:Dietary Supplements; D005260:Female; D005500:Follow-Up Studies; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic; D011446:Prospective Studies; D058996:Quality Improvement; D057566:Self Report; D014815:Vitamins / Q000097:blood / Q000627:therapeutic use*; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D015415:Biomarkers; D014815:Vitamins