title: [Neuroendocrine Tumor of the Ampulla of Vater and Gastrointestinal Stromal Tumor of the Duodenum in a Patient with Von Recklinghausen's Disease].
abstract: A 57-year-old woman with von Recklinghausen's disease presented with epigastralgia. Gastroduodenoscopy revealed swelling of the ampulla of Vater in the ventral and caudal direction, forming a hard, elastic mass. She was diagnosed with a tumor of the ampulla of Vater, and a subtotal stomach-preserving pancreaticoduodenectomy and D2 lymph node dissection were performed. The isolated specimen showed an intra-ampullary tumor of the ampulla of Vater and a submucosal tumor in the descending duodenum, which were diagnosed as a somatostatin-producing neuroendocrine tumor and gastrointestinal stromal tumor, respectively, on pathological examination. We believe that the neuroendocrine tumor of the ampulla of Vater and gastrointestinal stromal tumor of the duodenum are common gastrointestinal lesions in von Recklinghausen's disease.
authors.affiliation: Dept. of Surgery, Tokyo Women's Medical University Medical Center East.
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Yamada
authors.forename: Shunichi
authors.initials: S
authors.lastname: Shiozawa
authors.forename: Takebumi
authors.initials: T
authors.lastname: Usui
authors.forename: Kotaro
authors.initials: K
authors.lastname: Kuhara
authors.forename: Teppei
authors.initials: T
authors.lastname: Kouno
authors.forename: Shinichi
authors.initials: S
authors.lastname: Asaka
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Hazime
authors.initials: H
authors.lastname: Yokomizo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shimakawa
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Yoshimatsu
authors.forename: Takao
authors.initials: T
authors.lastname: Katsube
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Naritaka
mesh_terms: D014670:Ampulla of Vater / Q000473:pathology* / Q000601:surgery; D001650:Bile Duct Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D018278:Carcinoma, Neuroendocrine / Q000150:complications / Q000601:surgery; D003137:Common Bile Duct Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D004379:Duodenal Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000150:complications / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery; D009456:Neurofibromatosis 1 / Q000150:complications*