title: IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients.
authors.affiliation: Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven - University of Leuven, Leuven, Belgium.
authors.forename: T
authors.identifier: 0000-0002-1969-7974
authors.initials: T
authors.lastname: Dierckx
authors.affiliation: Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven - University of Leuven, Leuven, Belgium.|Instituto Gonçalo Moniz-FIOCRUZ, Salvador-Bahia, Brazil.
authors.forename: R
authors.initials: R
authors.lastname: Khouri
authors.affiliation: Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven - University of Leuven, Leuven, Belgium.
authors.forename: S M
authors.initials: SM
authors.lastname: Menezes
authors.affiliation: Instituto Gonçalo Moniz-FIOCRUZ, Salvador-Bahia, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Decanine
authors.affiliation: Instituto Gonçalo Moniz-FIOCRUZ, Salvador-Bahia, Brazil.
authors.forename: L
authors.initials: L
authors.lastname: Farre
authors.affiliation: Hospital Universitário Professor Edgar Santos-UFBA, Salvador-BA, Brazil.
authors.forename: A
authors.initials: A
authors.lastname: Bittencourt
authors.affiliation: Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven - University of Leuven, Leuven, Belgium.|Center for Global Health and Tropical Medicine, Unidade de Microbiologia, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.
authors.forename: A M
authors.initials: AM
authors.lastname: Vandamme
authors.affiliation: Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven - University of Leuven, Leuven, Belgium.|Instituto Gonçalo Moniz-FIOCRUZ, Salvador-Bahia, Brazil.
authors.forename: J
authors.identifier: 0000-0003-3234-8426
authors.initials: J
authors.lastname: Van Weyenbergh
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000494:pharmacology*; D016899:Interferon-beta / Q000494:pharmacology*; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000473:pathology*; D007963:Leukocytes, Mononuclear / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D015398:Signal Transduction / Q000187:drug effects; D014407:Tumor Cells, Cultured; D016159:Tumor Suppressor Protein p53 / Q000187:drug effects / Q000378:metabolism; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents; D016898:Interferon-alpha; C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; D016899:Interferon-beta