title: Hantavirus infection: a global zoonotic challenge.
abstract: Hantaviruses are comprised of tri-segmented negative sense single-stranded RNA, and are members of the Bunyaviridae family. Hantaviruses are distributed worldwide and are important zoonotic pathogens that can have severe adverse effects in humans. They are naturally maintained in specific reservoir hosts without inducing symptomatic infection. In humans, however, hantaviruses often cause two acute febrile diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). In this paper, we review the epidemiology and epizootiology of hantavirus infections worldwide.
authors.affiliation: Center for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710032, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
authors.affiliation: Center for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710032, China.
authors.forename: Xuyang
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Microbiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China.
authors.forename: Limei
authors.initials: L
authors.lastname: Wang
authors.affiliation: Center for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710032, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Du
authors.affiliation: Center for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710032, China. wangpz63@126.com.
authors.forename: Pingzhong
authors.initials: P
authors.lastname: Wang
authors.affiliation: Center for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710032, China. xfbai2011@163.com.
authors.forename: Xuefan
authors.initials: X
authors.lastname: Bai
mesh_terms: D000818:Animals; D004197:Disease Reservoirs; D014943:Global Health; D006476:Orthohantavirus / Q000254:growth & development; D018804:Hantavirus Pulmonary Syndrome / Q000453:epidemiology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology*; D006801:Humans; D015047:Zoonoses / Q000453:epidemiology* / Q000635:transmission
keywords: Bunyaviridae; hantavirus; hantavirus cardiopulmonary syndrome; hemorrhagic fever with renal syndrome; zoonosis