title: Does diet mediate associations of volume and bouts of sedentary time with cardiometabolic health indicators in adolescents?
abstract: Examine the mediating role of diet in the relationship between volume and duration of sedentary time with cardiometabolic health in adolescents.
  
  
  
  Adolescents (12-19 years) participating in the 2003/04 and 2005/06 U.S. National Health and Nutrition Examination Survey (NHANES) were examined. Cardiometabolic health indicators were body mass index z-scores (zBMI) (n = 1,797) and metabolic syndrome (MetS) (n = 812). An ActiGraph hip-worn accelerometer was used to derive total sedentary time and usual sedentary bout duration. Dietary intake was assessed using two 24-hour dietary recalls. Mediation analyses were conducted to examine five dietary mediators [total energy intake, discretionary foods, sugar-sweetened beverages (SSB), fruits and vegetables, and dietary quality] of the relationship between total sedentary time and usual sedentary bout duration with zBMI and MetS.
  
  
  
  Total sedentary time was inversely associated with zBMI (β = -1.33; 95% CI -2.53 to -0.13) but attenuated after adjusting for moderate-to-vigorous physical activity. No significant associations were observed between usual sedentary bout duration with zBMI or either sedentary measure with MetS. None of the five dietary variables mediated any of the relationships examined.
  
  
  
  Further studies are needed to explore associations of specific time periods (e.g., after school) and bout durations with both cardiometabolic health indicators and dietary behaviors.
authors.affiliation: School of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong, Australia.
authors.forename: Elly A
authors.initials: EA
authors.lastname: Fletcher
authors.affiliation: Faculty of Physical Education and Recreation, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Valerie
authors.initials: V
authors.lastname: Carson
authors.affiliation: School of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong, Australia.
authors.forename: Sarah A
authors.initials: SA
authors.lastname: McNaughton
authors.affiliation: School of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong, Australia.|Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.|Department of Medicine, Monash University, Melbourne, Victoria, Australia.|School of Public Health, The University of Queensland, Brisbane, Queensland, Australia.|Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.|School of Sport Science, Exercise and Health, The University of Western Australia, Perth, Western Australia, Australia.
authors.forename: David W
authors.initials: DW
authors.lastname: Dunstan
authors.affiliation: Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.|School of Public Health, The University of Queensland, Brisbane, Queensland, Australia.|School of Physiotherapy, Curtin University, Perth, Western Australia, Australia.
authors.forename: Genevieve N
authors.initials: GN
authors.lastname: Healy
authors.affiliation: School of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong, Australia.
authors.forename: Jo
authors.initials: J
authors.lastname: Salmon
mesh_terms: D061725:Accelerometry; D000293:Adolescent; D015992:Body Mass Index; D002648:Child; D003430:Cross-Sectional Studies; D004032:Diet; D002149:Energy Intake / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000503:physiopathology; D009749:Nutrition Surveys; D057185:Sedentary Behavior; D055815:Young Adult