[Prostaglandins and optic papilla blood flow].
Recent studies found that peripapillary microcirculation was damaged in glaucoma patients, indicating that blood flow in the optic nerve head is important in the pathogenesis of glaucoma. Effects of different antiglaucoma drugs on optic papilla blood flow deserve attention. Prostaglandins is the first line antiglaucoma drug. The experimental and clinical studies on the potential of prostaglandins to modify the blood flow in the optic papilla and related mechanisms are reviewed in this article. Effects of ocular blood flow increase on the treatment of glaucoma require further investigations.(Chin J Ophthalmol, 2017, 53: 73-76).
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
S H
SH
Zhang
J L
JL
Zhao
D001783:Blood Flow Velocity; D005901:Glaucoma / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007429:Intraocular Pressure; D008833:Microcirculation / Q000187:drug effects*; D009898:Optic Disk / Q000098:blood supply* / Q000187:drug effects*; D011453:Prostaglandins / Q000494:pharmacology*; D012039:Regional Blood Flow
D011453:Prostaglandins
Microcirculation; Optic disk; Prostaglandins; Regional blood flow; Retina