Subjective craving and event-related brain response to olfactory and visual chocolate cues in binge-eating and healthy individuals.
High-sugar/high-fat foods are related to binge-eating behaviour and especially people with low inhibitory control may encounter elevated difficulties to resist their intake. Incentive sensitization to food-related cues might lead to increased motivated attention towards these stimuli and to cue-induced craving. To investigate the combined influence of olfactory and visual stimuli on craving, inhibitory control and motivated attention, 20 healthy controls and 19 individuals with binge-eating viewed chocolate and neutral pictures, primed by chocolate or neutral odours. Subjective craving and electroencephalogram activity were recorded during the task. N2 and Late Positive Potential (LPP) amplitudes were analysed. Patients reported higher craving than controls. Subjective craving, N2 and LPP amplitudes were higher for chocolate versus neutral pictures. Patients showed a higher relative increase in N2 amplitudes to chocolate versus neutral pictures than controls. Chocolate images induced significant increases in craving, motivated attention and measures of cognitive control. Chocolate odour might potentiate the craving response to visual stimuli, especially in patients with binge-eating.
Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain.|Ciber Fisiopatologia Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Barcelona, Spain.
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Wolz
Addictology and Liaison Psychiatry Department, Nantes University Hospital. Nantes, France.|EA 4275 SPHERE "Methods for Patients Centered Outcomes and Health Research", University of Nantes, France.
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Sauvaget
Ciber Fisiopatologia Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Barcelona, Spain.|Department of Psychobiology and Methodology. University Autònoma of Barcelona, Spain.
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Granero
Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain.|Ciber Fisiopatologia Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Barcelona, Spain.
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Mestre-Bach
Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain.|Ciber Fisiopatologia Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Barcelona, Spain.
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Baño
Department of Psychobiology and Methodology. University Autònoma of Barcelona, Spain.
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Martín-Romera
Department of Clinical Sciences, School of Medicine, University of Barcelona, Spain.
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Veciana de Las Heras
Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain.|Ciber Fisiopatologia Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Barcelona, Spain.
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Jiménez-Murcia
Clinical Psychological Science, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
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Jansen
Clinical Psychological Science, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
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Roefs
Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain.|Ciber Fisiopatologia Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Barcelona, Spain.
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Fernández-Aranda
D000328:Adult; D000704:Analysis of Variance; D001921:Brain / Q000502:physiology*; D002032:Bulimia / Q000503:physiopathology*; D016022:Case-Control Studies; D000069956:Chocolate; D066249:Craving; D003463:Cues; D004569:Electroencephalography; D055724:Electrophysiological Phenomena; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009830:Olfactory Bulb / Q000502:physiology*; D057566:Self Report; D055815:Young Adult