Which perseverative behaviors are symptoms of spatial neglect?
Spatial neglect is a characterized by a failure to attend or make movements towards left-sided stimuli. Common paper-and-pencil tasks to diagnose spatial neglect are sensitive to perseverative errors, including additional marks over already cancelled targets and "scribbling" out a target. Here, we examine whether functionally distinct perseverative behaviors are related to spatial neglect. Line cancellation tasks of 45 healthy controls and 220 right-hemisphere stroke survivors were examined for recurrent marks (RM) and continuous marks (CM) perseverations. We found that RM perseveration correlated with neglect severity, while CM perseveration did not. Examination of lesion profiles for the two groups indicated distinct anatomical correlates, with RM lesions overlapping regions implicated in spatial neglect including the rolandic operculum, superior temporal gyrus, and inferior parietal lobule.
Stroke Rehabilitation Research, Kessler Foundation, West Orange, NJ, USA; Department of Psychology, Lafayette College, Easton, PA, USA. Electronic address: meghandcaulfield@gmail.com.
Meghan D
MD
Caulfield
Stroke Rehabilitation Research, Kessler Foundation, West Orange, NJ, USA; Department of Physical Medicine and Rehabilitation, Rutgers-New Jersey Medical School, Newark, NJ, USA.
Peii
P
Chen
Stroke Rehabilitation Research, Kessler Foundation, West Orange, NJ, USA.
Michele M
MM
Barry
Stroke Rehabilitation Research, Kessler Foundation, West Orange, NJ, USA; Department of Physical Medicine and Rehabilitation, Rutgers-New Jersey Medical School, Newark, NJ, USA; Kessler Institute for Rehabilitation, West Orange, NJ, USA.
A M
AM
Barrett
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000473:pathology*; D010468:Perceptual Disorders / Q000175:diagnosis / Q000473:pathology / Q000523:psychology*; D011597:Psychomotor Performance / Q000502:physiology; D012720:Severity of Illness Index; D020521:Stroke / Q000473:pathology / Q000523:psychology*; D013702:Temporal Lobe / Q000473:pathology*; D055815:Young Adult
Activities of daily living; Allochiria; Barthel index; Disengagement of attention; Functional disability; Hyperkinesia; Lesion mapping; Motor disinhibition; Motor perseveration; Neglect; Perseveration; Spatial motor; Spatial representation; Stroke; Working memory