Did food allergy develop in the process of animal evolution?
Food allergy is pathophysiologic ally based on stimulation of the immune system at the first exposure, and allergic reactions develop during following exposures. Therefore, memory is the cornerstone of an allergy, as seen in the adaptive immune system. The adaptive immune system was first introduced during evolution in vertebrates, so we can say that invertebrates do not have allergic reactions. We can conclude that food allergy is a complication of animal evolution. Evolution also can cause diseases and complications; therefore, understanding it may help in allergy treatment.
M.D., Professor, Department of Immunology and Allergy, Faculty of Medicine, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Hesamedin
SH
Nabavizadeh
Student of Dentistry, Faculty of Dentistry, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sara Sadat
SS
Nabavizadeh
M.D., Faculty Member, Department of Internal Medicine, Faculty of Medicine, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Amir
A
Anushiravani
Food allergy; Hypersensitivity; Immune system