Update on Surgical Outcomes of Lateral Temporal Bone Resection for Ear and Temporal Bone Malignancies.
ObjectivesReview outcomes of lateral temporal bone resections for ear and temporal bone malignancy.Design, Setting, and ParticipantsRetrospective review of all lateral temporal bone resections performed from 2008 to 2015 at a single tertiary care center.Main Outcome MeasuresPatient demographics, perioperative variables, overall survival, disease-free survival (DFS), and comparison of Kaplan-Meier curves.ResultsOverall, 56 patients were identified with a mean follow-up period of 2.3 ± 1.8 years. The predominant histopathologic diagnosis was squamous cell carcinoma (SCC, 54%), followed by salivary gland tumors (18%), and basal cell carcinoma (9%). Tumor stages were T1-T2 in 23%, T3-T4 in 73%, and two unknown primary lesions. Mean overall survival was 4.6 ± 0.4 years. Comparison of tumors with and without lymph node involvement or perineural invasion approached statistical significance for overall survival (p= 0.07 and 0.06, respectively). DFS was 2.5 ± 0.3 years. Stratification by lymph node status had a statistically significant difference in DFS (p= 0.03). Subgroup analysis of SCC patients did not reveal significant differences.ConclusionsBased on our cohort, most patients with temporal bone malignancies present with advanced disease, making it difficult to achieve negative margins. Overall, lymph node status was the strongest predictor of survival in this group.
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States.
Sumi
S
Sinha
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States.
Matthew M
MM
Dedmon
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States.
Matthew R
MR
Naunheim
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States.
Jennifer C
JC
Fuller
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States.
Stacey T
ST
Gray
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States.
Derrick T
DT
Lin
cancer; lateral temporal bone resection; malignancy; outcomes