Diastereoselective tandem oxidation/Michael/aldol reaction: unprecedented formation of dispirocyclopentanebisoxindoles and dispiro[acenaphthylene-1,1'-cyclopentane-3',1''-acenaphthylene]-2,2''diones.
An unprecedented tandem oxidation/Michael/aldol reaction is reported. The diastereoselective formation of only a single isomer of dispirocyclopentanebisoxindole and dispiro[acenaphthylene-1,1'-cyclopentane-3',1''-acenaphthylene]-2,2''dione is presented. The reaction generates two new C-C bonds and two all-carbon quaternary chiral stereocenters in a single step.
Organic and Bioorganic Chemistry Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai, Tamilnadu, India-600020. thennarasu@gmail.com.
Koorathota
K
Suman
Organic and Bioorganic Chemistry Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai, Tamilnadu, India-600020. thennarasu@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bahavan, 2 Rafi Marg, New Delhi-110001, India.
Mala
M
Ramanjaneyulu
Organic and Bioorganic Chemistry Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai, Tamilnadu, India-600020. thennarasu@gmail.com and Academy of Scientific and Innovative Research (AcSIR), Anusandhan Bahavan, 2 Rafi Marg, New Delhi-110001, India.
Sathiah
http://orcid.org/0000-0001-8439-4438
S
Thennarasu