Physical, chemical and antimicrobial evaluation of a composite material containing quaternary ammonium salt for braces cementation.
The antibiofilm effect of iodide quaternary ammonium methacryloxy silicate (IQAMS) in Transbond XT Light Cure Adhesive resin used for braces cementation was evaluated. Fourier Transform Infrared (FTIR) spectroscopy confirmed IQAMS formation and Scanning Electron Microscopy coupled to Energy-Dispersive X-ray Spectroscopy (SEM-EDS) revealed that as coating, the quaternary ammonium groups from IQAMS were homogeneously dispersed throughout the surface. When incorporated, the composite material presented homogeneous dispersion throughout the resin. Assays with Streptococcus mutans demonstrated enhanced antibiofilm effect for the IQAMS coated resin, with much lower colony-forming units (CFU), in comparison to incorporated IQAMS. Such a difference was assigned to low availability of quaternary ammonium groups at the surface of resin when IQAMS was incorporated, hindering its antibiofilm effect. Additionally, the incorporation of IQAMS led to slight decrease in ultimate bond strength (UBS) and shear bond strength (SBS), in comparison to the neat commercial resin. Thus, the synthesized IQAMS displays great potential as antibiofilm coating or sealant to prevent oral infections in brackets during orthodontic treatment.
Departamento de Odontologia Restaurativa, Faculdade de Odontologia de Piracicaba - Universidade de Campinas, Piracicaba, SP 13414-903, Brazil.
Mari Miura
MM
Sugii
Grupo de Química de Materiais Híbridos e Inorgânicos, Instituto de Química de São Carlos - Universidade de São Paulo, São Carlos, SP 13563-120, Brazil. Electronic address: ferreira.fabio.a.s@gmail.com.
Fábio Augusto de Souza
FAS
Ferreira
Departamento de Ciências Fisiológicas, Área de Farmacologia, Anestesiologia e Terapeutica, Faculdade de Odontologia de Piracicaba - Universidade de Campinas, Piracicaba, SP 13414-903, Brazil.
Karina Cogo
KC
Müller
Departamento de Odontologia Restaurativa, Faculdade de Odontologia de Piracicaba - Universidade de Campinas, Piracicaba, SP 13414-903, Brazil.
Debora Alves Nunes Leite
DANL
Lima
Departamento de Ciências Fisiológicas, Área de Farmacologia, Anestesiologia e Terapeutica, Faculdade de Odontologia de Piracicaba - Universidade de Campinas, Piracicaba, SP 13414-903, Brazil.
Francisco Carlos
FC
Groppo
Grupo de Química de Materiais Híbridos e Inorgânicos, Instituto de Química de São Carlos - Universidade de São Paulo, São Carlos, SP 13563-120, Brazil.
Hidetake
H
Imasato
Grupo de Química de Materiais Híbridos e Inorgânicos, Instituto de Química de São Carlos - Universidade de São Paulo, São Carlos, SP 13563-120, Brazil.
Ubirajara Pereira
UP
Rodrigues-Filho
Departamento de Odontologia Restaurativa, Faculdade de Odontologia de Piracicaba - Universidade de Campinas, Piracicaba, SP 13414-903, Brazil.
Flávio Henrique Baggio
FHB
Aguiar
D000890:Anti-Infective Agents / Q000494:pharmacology*; D001672:Biocompatible Materials / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects; D001915:Braces; D002484:Cementation; D015169:Colony Count, Microbial; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D019279:Resin Cements; D012492:Salts / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D017550:Spectroscopy, Fourier Transform Infrared; D013295:Streptococcus mutans / Q000187:drug effects / Q000502:physiology
D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D000644:Quaternary Ammonium Compounds; D019279:Resin Cements; D012492:Salts; C477790:Transbond XT
Antibiofilm; Methacrylate; Orthodontic; Quaternary ammonium; Streptococcus mutans