Diet and the Microbiome.
The gut microbiota provides a range of ecologic, metabolic, and immunomodulatory functions relevant to health and well-being. The gut microbiota not only responds quickly to changes in diet, but this dynamic equilibrium may be managed to prevent and/or treat acute and chronic diseases. This article provides a working definition of the term "microbiome" and uses two examples of dietary interventions for the treatment of large bowel conditions to emphasize the links between diet and microbiome. There remains a need to develop a better functional understanding of the microbiota, if its management for clinical utility is to be fully realized.
The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, Queensland 4102, Australia.
Nida
N
Murtaza
The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, Queensland 4102, Australia.
Páraic
P
Ó Cuív
The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, Queensland 4102, Australia. Electronic address: m.morrison1@uq.edu.au.
Mark
M
Morrison
D000818:Animals; D004032:Diet; D000069196:Gastrointestinal Microbiome; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000178:diet therapy / Q000382:microbiology*; D043183:Irritable Bowel Syndrome / Q000178:diet therapy / Q000382:microbiology*
Diet; Gut; Inflammatory bowel disease; Irritable bowel syndrome; Microbiome; Microbiota