Neuroglial intramedullary tumors: The collaboration between neurosurgeons and neuropathologists.
Intramedullary tumors constitute approximately 5% of spinal tumors and about 80% are of neuroglial origin. We reviewed our series of adult patients with spinal neuroglial intramedullary tumors operated on between 1984 and 2011 at the neurosurgical department of Bicêtre hospital. The histopathological records for 196 patients were retrospectively analyzed. The majority of tumors were ependymomas (68%) and astrocytomas (27.5%). The importance of a proper and detailed neuropathological diagnosis is the key to define patient management. The available literature data about the genetic profiles of these rare tumors are summarized and reviewed.
Department of neurosurgery, university hospital of Lausanne, 46, rue du Bugnon, 1010 Lausanne, Switzerland. Electronic address: giulia.cossu@chuv.ch.
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Cossu
Department of neuropathology, Bicêtre hospital, Paris-Sud university, 94270 Paris, France.
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Lacroix
Department of neuropathology, Bicêtre hospital, Paris-Sud university, 94270 Paris, France.
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Adams
Department of neurosurgery, university hospital of Lausanne, 46, rue du Bugnon, 1010 Lausanne, Switzerland.
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Daniel
Department of neurosurgery, Bicêtre hospital, Paris-Sud university, 94270 Paris, France.
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Parker
Department of neurosurgery, university hospital of Lausanne, 46, rue du Bugnon, 1010 Lausanne, Switzerland; Department of neurosurgery, Bicêtre hospital, Paris-Sud university, 94270 Paris, France.
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Messerer
D001254:Astrocytoma / Q000473:pathology / Q000601:surgery; D004806:Ependymoma / Q000473:pathology / Q000601:surgery; D005910:Glioma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007400:Interprofessional Relations; D000069338:Neuropathology; D009493:Neurosurgery; D012189:Retrospective Studies; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000601:surgery*
Astrocytoma; Ependymoma; Gangliocytoma; Intramedullary tumors; Neuroglial tumors; Spinal cord