Ethnomedical survey and safety evaluation of traditional eye medicines used in Misungwi district, Tanzania.
OBJECTIVE
This study aimed at documenting products used as traditional eye medicine (TEM) in Misungwi district, Tanzania, and performing preliminary analysis on safety status.


METHODS
Ethnomedical study was conducted in Misungwi district. Information was sourced by face-to-face interview with traditional healers, traditional medicine vendors, and knowledgeable people guided by a well-structured questionnaire. Safety was evaluated by determining pH using pH meter and mineral analysis using the Delta, Portable X-ray fluorescence equipment, and qualitative chemical tests.


RESULTS
A total of 23 TEM products were recorded from botanical (79%) and zoological (21%) sources including animal excreta. Liquid preparation ranked highest among dosage forms. Safety evaluation showed that only one product possessed the pH value of 7.4 as recommended for topical ophthalmic medicines. Fourteen minerals were detected and quantified in three samples; some of these minerals are known for their negative effects to the eyes, of medical interest is strontium used for the management of benign eye tumors. Information providers were unaware of health risks associated with the use of TEM.


CONCLUSIONS
This study has revealed the common use of TEM in Misungwi district. The majority of the products are from the botanical source. Although literature provides supporting data for the application to some of the recorded TEM, safety evaluation by pH and mineral analysis in this study have indicated possible ophthalmological medical problems that could result from using such products. Extensive scientific studies including animal experiments and identification of bioactive compounds are essential to develop safe TEMs.
Department of Pharmacognosy, Muhimbili University of Health and Allied Sciences, University of Dar es Salaam, Dar es Salaam, Tanzania.
Sheila M
SM
Maregesi
Department of Pharmacognosy, Muhimbili University of Health and Allied Sciences, University of Dar es Salaam, Dar es Salaam, Tanzania.
Charles W
CW
Messo
Department of Pharmacognosy, Muhimbili University of Health and Allied Sciences, University of Dar es Salaam, Dar es Salaam, Tanzania.
Juma
J
Mathias
Ethnomedical; Misungwi district; Tanzania; minerals; pH; safety; traditional eye medicine