Necrotizing Enterocolitis and Human Milk Feeding: A Systematic Review.
This article summarizes evidence regarding whether a donor human milk (DHM) and/or an exclusively human milk (EHM) diet decreases the incidence of necrotizing enterocolitis (NEC) and the dose of human milk (HM) necessary to reduce the risk of NEC in premature infants. Additional research regarding protection afforded by DHM and EHM is necessary as well as research elucidating the exact dose of HM necessary for NEC risk reduction. Research is also needed to determine whether there is a dose-dependent effect of DHM, a combination of mother's own milk and DHM, and an EHM diet on NEC incidence.
Division of Neonatology, Department of Pediatrics, University of Florida, 1600 Southwest Archer Road, HD-118, Gainesville, FL 32610, USA. Electronic address: nicole.cacho@peds.ufl.edu.
Nicole Theresa
NT
Cacho
Biobehavioral Nursing Science, College of Nursing, University of Florida, PO Box 100187, HPNP 2227, Gainesville, FL 32610-0187, USA.
Leslie A
LA
Parker
Division of Neonatology, Department of Pediatrics, University of Florida, 1600 Southwest Archer Road, HD-112, Gainesville, FL 32610, USA.
Josef
J
Neu
D001942:Breast Feeding / Q000706:statistics & numerical data*; D061186:Breast Milk Expression / Q000706:statistics & numerical data; D020345:Enterocolitis, Necrotizing / Q000453:epidemiology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008895:Milk, Human; D065840:Protective Factors; D009927:Tissue and Organ Procurement
Donor milk; Exclusive human milk; Human milk; Necrotizing enterocolitis; Premature infant