Current views on fetal surgical treatment of myelomeningocele - the Management of Myelomeningocele Study (MOMS) trial and Polish clinical experience.
Myelomeningocele (MMC) is the most frequent congenital defect of the central nervous system for which there is no satisfactory alternative to postnatal treatment. On the contrary prenatal MMC surgery is conducting before birth and is aimed at protecting from Chiari II malformation. The main goal of fetal MMC repair is to improve development and life quality of children with Chiari II malformation. Management of Myelomeningocele Study (MOMS) which was published in 2011 clearly confirmed effectiveness of prenatal surgery. In this paper we compare MOMS results with our own clinical experience. Thanks to high effectiveness and significant improvement in safety of maternal-fetal surgery prenatal MMC surgery become a new standard of treatment.
Jacek
J
Zamłyński
Ewa
E
Horzelska
Medical University of Silesia Poland. m.zamlynski@hotmail.com.
Mateusz
M
Zamłyński
Katarzyna
K
Olszak-Wąsik
Leszek
L
Nowak
Piotr
P
Bodzek
Tomasz
T
Horzelski
Rafał
R
Bablok
Anita
A
Olejek
D001139:Arnold-Chiari Malformation / Q000601:surgery*; D018450:Disease Progression; D004677:Encephalocele; D005260:Female; D046128:Fetal Therapies / Q000379:methods*; D005333:Fetus / Q000601:surgery*; D006801:Humans; D006849:Hydrocephalus; D008591:Meningomyelocele / Q000601:surgery*; D011044:Poland; D011247:Pregnancy; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic
operacje wewnątrzmaciczne; przepuklina oponowo-rdzeniowa; rozszczep kręgosłupa; zespół Chari II