Radiographic involvement of metacarpophalangeal and radiocarpal joints in hand osteoarthritis.
To evaluate, by means of a longitudinal study, radiographic involvement of metacarpophalangeal and radio-carpal joints in hand osteoarthritis, its relationship with erosive disease and its progression, 368 patients with hand osteoarthritis were enrolled. All patients underwent hand X-rays. On the basis of the presence of central erosions in interphalangeal joints, patients were divided into three groups: 0-no central erosions, 1-one joint with central erosion, and 2-two or more joints with central erosions. A longitudinal study on 44 patients and nine normal controls, whose X-rays were available after 3.9 years, was performed. The radiological involvement of metacarpophalangeal and radio-carpal joints was evaluated using Kellgren-Lawrence and OARSI scores. Low number of joints showed Kellgren-Lawrence values ≥2 group 0, 42/1290 (3.3%); group 1, 10/410 (2.4%); and group 2, 36/1980 (1.8%). Low score values were obtained for all radiographic items. Only metacarpophalangeal joint space narrowing score showed significant increase from groups 0 to 2. Subsequent adjustment for age, gender, and BMI did not confirm the statistical significance. Marginal erosions were rarely found (6.7% of joints). Metacarpophalangeal and radio-carpal radiographic per patient scores significantly worsened at follow-up, but no significant increase in joints with Kellgren-Lawrence score ≥2 was found. In normal controls, no significant radiographic worsening was found. Only a minority of metacarpophalangeal joints shows a Kellgren-Lawrence value ≥2. Metacarpophalangeal and to lesser extent radiocarpal joints had significant worsening at follow-up. Metacarpophalangeal joint involvement in hand osteoarthritis is mild but progressive. Radiocarpal involvement is negligible.
Medicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, 40136, Bologna, Italy. olga.addimanda@ior.it.|Dept of Biomedical & Neuromotor Sciences, University of Bologna, Bologna, Italy. olga.addimanda@ior.it.
Olga
http://orcid.org/0000-0002-1267-5764
O
Addimanda
Medicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, 40136, Bologna, Italy.
Carlotta
C
Cavallari
Statistics Unit, Rizzoli Orthopaedic Institute, Bologna, Italy.
Elettra
E
Pignotti
Immunorheumatology and Tissue regeneration, Rizzoli Orthopaedic Institute, Bologna, Italy.
Lia
L
Pulsatelli
Medicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, 40136, Bologna, Italy.
Luana
L
Mancarella
DIMED, University of Padova, Padova, Italy.
Roberta
R
Ramonda
Rheumatology Unit, Department of Clinical Medicine and Immunological Science, University of Siena, Siena, Italy.
Antonella
A
Fioravanti
Medicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, 40136, Bologna, Italy.|Dept of Biomedical & Neuromotor Sciences, University of Bologna, Bologna, Italy.
Riccardo
R
Meliconi
D000368:Aged; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging*; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging*; D011859:Radiography / Q000379:methods*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors; D014955:Wrist Joint / Q000000981:diagnostic imaging*
Imaging–radiology; OA