Intraoperative Margin Assessment in Early Oral Squamous Cell Carcinoma.
The surgical method of margin sampling affects local control, pathologists' approach to margin sampling, and clarity of pathology reports. Studies have shown that exclusive reliance on tumor bed margins is associated with worse local control and should be avoided. En bloc resections and margins obtained from the resection specimen remain the "gold standard." Successful surgical treatment of early carcinomas of the oral cavity relies on close cooperation between surgeons and pathologists on issues of specimen orientation and margin sampling.
Department of Pathology, Presbyterian University Hospital, University of Pittsburgh Medical Center, A610.3, 200 Lothrop Street, Pittsburgh, PA 15213, USA. Electronic address: chioseasi@upmc.edu.
Simion I
SI
Chiosea
D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005629:Frozen Sections; D005927:Glossectomy / Q000379:methods; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D000072662:Margins of Excision; D009062:Mouth Neoplasms / Q000473:pathology / Q000601:surgery*; D013048:Specimen Handling / Q000379:methods
Frozen; Gross examination; Margin; Oral cavity; Squamous cell carcinoma