MoS2/reduced graphene oxide nanocomposite for sensitive sensing of cysteamine in presence of uric acid in human plasma.
A hybrid nanocomposite of MoS2nanosheets and reduced graphene oxide (rGO) was fabricated by a facile and effective method. The morphology and structure of the nanocomposite (MoS2-rGO) were characterized by scanning electron microscopy, X-ray photoelectron spectroscopy, Raman spectroscopy, electrochemical impedance spectroscopy and cyclic voltammetry. The MoS2nanosheets were uniformly anchored on the rGO framework with strong adhesion. A glassy carbon electrode modified by drop-casting with MoS2-rGO was used for the electrochemical oxidation of cysteamine (CA) in the presence of uric acid (UA). Under optimum conditions, the anodic peak current of CA shows a linear relation with the CA concentration between 0.01 and 20μM with a detection limit of 7nM. The proposed electrochemical sensor was used for determination of CA in human plasma.
Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran. Electronic address: fchekin@yahoo.com.
Fereshteh
F
Chekin
Univ. Lille, CNRS, Centrale Lille, ISEN, Univ. Valenciennes, UMR 8520 - IEMN, F-59000 Lille, France.
Rabah
R
Boukherroub
Univ. Lille, CNRS, Centrale Lille, ISEN, Univ. Valenciennes, UMR 8520 - IEMN, F-59000 Lille, France.
Sabine
S
Szunerits
D002138:Calibration; D002384:Catalysis; D003543:Cysteamine / Q000097:blood*; D058266:Dielectric Spectroscopy; D004220:Disulfides / Q000737:chemistry*; D055664:Electrochemical Techniques; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D008982:Molybdenum / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D010084:Oxidation-Reduction; D056951:Photoelectron Spectroscopy; D015203:Reproducibility of Results; D012996:Solutions; D013052:Spectrometry, X-Ray Emission; D013059:Spectrum Analysis, Raman; D014527:Uric Acid / Q000737:chemistry*
D004220:Disulfides; D012996:Solutions; D014527:Uric Acid; D003543:Cysteamine; D006108:Graphite; D008982:Molybdenum; C082964:molybdenum disulfide
Cysteamine; MoS(2) nanosheets; Plasma; Reduced graphene oxide