An audit of the results of ultrasound-guided core needle biopsy of mammography versus ultrasound screen-detected breast lesions.
OBJECTIVE
To analyze the malignancy rate of ultrasound-guided core needle biopsy (US-CNB) for screen-detected breast lesions and to evaluate the results according to the mode of detection of the target lesions.


METHODS
This is a retrospective review of 703 consecutive women who underwent US-CNB for screen-detected breast lesions at a single tertiary hospital. Breast Imaging Reporting and Data System (BI-RADS) categories and histopathological results of the target lesions were assessed. The cases were divided into two groups: the mammography-based detected lesions (M-group) and the US-based detected lesions (U-group). The biopsy performances of the two groups were compared using the χ2test.


RESULTS
The malignancy rate in the entire population was 22.0%: 0.8%, 12.3%, 65.2%, 89.3%, and 94.6% in BI-RADS categories 3, 4A, 4B, 4C, and 5, respectively. The malignancy rate was significantly higher in the M-group (54.1% [79/146]) than in the U-group (13.6% [76/557]) (p < 0.001). BI-RADS category 3 was the most common assessment overall that led to a US-CNB (362/703, 51.5%) and the rate of BI-RADS category 3 diagnoses that led to US-CNB was significantly higher in the U-group (p < 0.001).


CONCLUSIONS
The malignancy rate associated with US-CNB for screen-detected breast lesions was 22.0%. The breast lesions detected by mammography have a higher malignancy rate than those detected by US. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 45:261-266, 2017.
Department of Radiology and Center for Imaging Science, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, Republic of Korea.|Department of Radiology, Kyung Hee University Hospital at Gangdong, 892, Dongnam-ro, Gangdong-gu, Seoul, Republic of Korea.
Sun Jung
SJ
Rhee
Department of Radiology and Center for Imaging Science, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, Republic of Korea.
Boo-Kyung
BK
Han
Department of Radiology and Center for Imaging Science, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, Republic of Korea.
Eun Sook
ES
Ko
Department of Radiology and Center for Imaging Science, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, Republic of Korea.
Ji Soo
JS
Choi
Department of Radiology and Center for Imaging Science, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, Republic of Korea.
Eun Young
EY
Ko
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D062005:Biopsy, Large-Core Needle; D001940:Breast / Q000000981:diagnostic imaging; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D008485:Medical Audit / Q000379:methods / Q000706:statistics & numerical data*; D008875:Middle Aged; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary / Q000379:methods*; D055815:Young Adult
BI-RADS; breast neoplasms; breast screening; ultrasound; ultrasound-guided breast biopsy