Disseminated Cryptococcosis with Rapidly Growing Lung Nodules in an End-stage Renal Disease Patient.
A 73-year-old man with type 2 diabetes mellitus and end-stage renal disease was diagnosed with acute myocardial infarction. He required continuous dialysis after percutaneous coronary intervention. Subsequently, multiple nodules were discovered in both lungs for the first time, and Cryptococcus neoformans was isolated from the patient's sputum, blood, bilateral pleural fluid, and cerebrospinal fluid cultures, resulting in a diagnosis of disseminated cryptococcosis. This case represents an invaluable example of disseminated cryptococcosis with rapidly growing lung nodules in a dialysis patient, and illustrates that dialysis causes innate immune disorder and the reactivation of cryptococcosis.
Department of Respiratory Medicine, Tokyo Teishin Hospital, Japan.
Atsushi
A
Inaba
Akira
A
Okada
Taiko
T
Yoshida
Satoshi
S
Itoyama
Tatsuro
T
Nakai
Tetsuya
T
Hisada
Hideki
H
Takano
D000368:Aged; D003453:Cryptococcosis / Q000150:complications* / Q000382:microbiology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D003924:Diabetes Mellitus, Type 2; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications / Q000382:microbiology*; D008297:Male; D051436:Renal Insufficiency, Chronic / Q000150:complications*; D013183:Sputum / Q000382:microbiology; D014132:Trachea / Q000382:microbiology