Development of primary central nervous system lymphoma in a systemic lupus erythematosus patient after treatment with mycophenolate mofetil and review of the literature.
Primary central nervous system lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin lymphoma and four cases of PCNSL have previously been described in association with mycophenolate mofetil. We report the fifth case of PCNSL in a patient with lupus nephropathy while on mycophenolate mofetil treatment.
1 Department of Rheumatology, Trakya University Medical Faculty, Edirne, Turkey.
M A
MA
Balci
2 Department of Hematology, Trakya University Medical Faculty, Edirne, Turkey.
G E
GE
Pamuk
3 Department of Radiology, Trakya University Medical Faculty, Edirne, Turkey.
E
E
Unlu
4 Department of Pathology, Trakya University Medical Faculty, Edirne, Turkey.
U
U
Usta
1 Department of Rheumatology, Trakya University Medical Faculty, Edirne, Turkey.
O N
ON
Pamuk
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D016543:Central Nervous System Neoplasms / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D038524:Diffusion Magnetic Resonance Imaging; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000009:adverse effects*; D016896:Treatment Outcome; D055815:Young Adult
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid
Systemic lupus erythematosus; haematological changes; nephritis