Gastric neuroendocrine tumor with hypergastrinemia following type B chronic atrophic gastritis: a case report.
A man in his 60s was referred to our institution for the evaluation of a gastric neuroendocrine tumor (G-NET) located in the fornix and that measured 13mm in size. Blood test results revealed hypergastrinemia (up to 3376pg/ml). Additional tests, including esophagogastroduodenoscopy, computed tomography, and intragastric pH monitoring, indicated that hypergastrinemia was not associated with type A autoimmune gastritis or gastrinoma. The patient was positive for the immunoglobulin G antibody against Helicobacter pylori, suggesting type B chronic atrophic gastritis as the cause for the condition. This report describes a rare case of G-NET with hypergastrinemia following type B chronic atrophic gastritis. Evaluation of similar cases is necessary to determine if H. pylori-associated chronic atrophic gastritis is frequently associated with G-NET.
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University.
Eriko
E
Yamaguchi
Tsutomu
T
Iwasa
Eikichi
E
Ihara
Yosuke
Y
Tomita
Akira
A
Aso
Eiji
E
Oki
Kayoko
K
Nakano
Minako
M
Hirahashi
Kazuhiko
K
Nakamura
D002908:Chronic Disease; D005755:Gastrins / Q000097:blood*; D005757:Gastritis, Atrophic / Q000209:etiology*; D016481:Helicobacter Infections / Q000150:complications / Q000276:immunology; D016480:Helicobacter pylori / Q000276:immunology; D006801:Humans; D008297:Male; D018358:Neuroendocrine Tumors / Q000150:complications*; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology*
D005755:Gastrins