[The Power of Phosphaturia in the Infrequent Hemodialysis].
BACKGROUND
Residual renal function (RRF) and phosphaturia had not stimulated particular interest in studies regarding patients on hemodialysis. In the current year the Authors have selected a series of patients with RRF undergoing infrequent hemodialysis treatments.


OBJECTIVE
The Authors have carried out a study of the phosphate balance in patients on infrequent hemodialysis with the hypothesis that the phosphaturia was always neglected in hemodialysis patients, but it could represent a positive impact element on the cardiovascular events and mortality in hemodialysis.


METHODS
During 6 months, the Authors have conducted forty urine collections in 10 patients on twice a week hemodialysis (TWH) (age: 69,3 years, dialysis vintage: 42,7 months and 40.9 months on TWH) and eighty urine collections in 8 patients on once a week hemodialysis and low-protein diet (CDDP) (age: 69.6 years, dialysis vintage: 24.7 months and 24 months in CDDP) to determine RRF and phosphaturia. We compared the balance of phosphate compared with a thrice-weekly hemodialysis considering on phosphate removal: dialysis efficiency, phosphate-binders power on the protein- phosphates intake and the extent of phosphaturia.


RESULTS
The patients on infrequent hemodialysis have demonstrated a significant share of urinary phosphate output leading to a weekly phosphoric balance equal to zero or even negative.


CONCLUSIONS
The phosphoric balance in infrequent hemodialysis patients is a decisive way to remove the phosphates, confirming that this factor could be decisive on the improved survival and reduced cardiovascular mortality compared to patients receiving thrice-weekly hemodialysis. The Authors stress again the need to keep as long as possible the FRR.
Piergiorgio
P
Bolasco
Stefano
S
Murtas
Stefania
S
Caria
Andrea
A
Galfrè
Maria Paola
MP
Esposito
Rita
R
Contu
Maria Luisa
ML
Deiana
Antonella
A
Serra
Katia
K
Cannas
Simonetta
S
Caria
Irene
I
Sitzia
Patrizia
P
Scotto
Pierluigi
P
Spiga
Gabriella
G
Concas
D000368:Aged; D005260:Female; D006801:Humans; D007015:Hypophosphatemia, Familial / Q000209:etiology / Q000628:therapy*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000503:physiopathology* / Q000628:therapy*; D008297:Male; D006435:Renal Dialysis / Q000706:statistics & numerical data*