Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum.
Colostrum is the main external resource providing piglets with nutrients and maternal immune molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in vitro and several animal models. This study aimed to determine the effects of APS on immune factors in sow colostrum and milk. The sow diet was supplemented with APS one week before the expected delivery date. Colostrum and milk were collected and designated as 0 h- (onset of parturition), 12 h-, and 24 h-colostrum and 36 h-milk postpartum. Samples were measured using porcine immunoglobulin (Ig) G, IgM, classical swine fever virus antibody (CSFV Ab), epidermal growth factor (EGF), and insulin-like growth factor- (IGF-) 1 ELISA Quantitation Kits. Dietary supplementation of APS significantly enhanced the presence of IgG, IgM, EGF, and IGF-1 in 0 h-colostrum (P< 0.001). The blocking rates of CSFV Ab were increased in samples from APS-supplemented sow when compared to those from the matched samples without APS treatment. The results indicate that supplement of APS could improve the immune components in sow colostrum and/or milk; and status of some specific vaccination could be determined through using colostrum or early milk in sow.
College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Lunbo
L
Tan
College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Ting
T
Wei
College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Anwen
A
Yuan
College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Jun
J
He
College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Jinhui
J
Liu
College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Daojun
0000-0003-3699-9488
D
Xu
College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Qing
0000-0002-5910-458X
Q
Yang
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D027883:Astragalus Plant / Q000378:metabolism*; D006692:Classical Swine Fever Virus / Q000276:immunology; D003126:Colostrum / Q000737:chemistry*; D019587:Dietary Supplements; D004815:Epidermal Growth Factor / Q000097:blood*; D005260:Female; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D028321:Plant Preparations / Q000494:pharmacology*; D011134:Polysaccharides / Q000494:pharmacology; D011247:Pregnancy; D013552:Swine
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D028321:Plant Preparations; D011134:Polysaccharides; D004815:Epidermal Growth Factor; D007334:Insulin-Like Growth Factor I