Management of aplastic anaemia in pregnancy in a resource poor centre.
Aplastic anaemia occurring in pregnancy is a rare event with life threatening challenges for both mother and child. We present a successful fetomaternal outcome despite the challenges in the management of this rare condition in a tertiary but resource poor centre. This is case of a 37 year old Nigerian woman G6P0+5managed with repeated blood transfusions from 28 weeks of gestation for bone marrow biopsy confirmed aplastic anaemia following presentation with weakness and gingival bleeds. She had a cesarean section at 37 weeks for pre-eclampsia and oligohydraminous with good feto-maternal outcome. She was managed entirely with fresh whole blood and received 21 units. Aplastic Anaemia in Pregnancy is a rare event with poor feto maternal prognosis. Successful management is possible with good multi-disciplinary approach and availability of supportive comprehensive obstetric care.
Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Celestine Osita
CO
John
Department of Haematology & Blood Transfusion, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Kaladada
K
Korubo
Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Rosemary
R
Ogu
Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Chigozirim Faith
CF
Mmom
Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Alpheus Gogo
AG
Mba
Department of Haematology & Blood Transfusion, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Ezenwa-Ahanene
EA
Chidiadi
Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Chris
C
Akani
D000328:Adult; D000741:Anemia, Aplastic / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D001706:Biopsy; D001803:Blood Transfusion / Q000379:methods; D002585:Cesarean Section / Q000379:methods; D005260:Female; D006801:Humans; D009549:Nigeria; D016104:Oligohydramnios / Q000175:diagnosis; D011225:Pre-Eclampsia / Q000175:diagnosis; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D011256:Pregnancy Outcome
Aplastic anaemia; absolute neutrophil count; bone marrow; cyclosporine; platelet concentrate; pregnancy; transfusion