A multinational report of technical factors on stereotactic body radiotherapy for oligometastases.
OBJECTIVE
Oligometastatic cancer is being increasingly managed with aggressive local therapy using stereotactic body radiation therapy (SBRT). However, few guidelines exist. We summarize the results of an international survey reviewing technical factors for extracranial SBRT for oligometastatic disease to guide safe management.


METHODS
Seven high-volume centers contributed. Levels of agreement were categorized as strong (6-7 common responses), moderate (4-5), low (2-3) or no agreement.


CONCLUSIONS
We present the results of a multi-national and multi-institutional survey of technical factors of SBRT for extracranial oligometastases. Key methods including target delineation, prescription doses, normal tissue constraints, imaging and set-up for safe implementation and practice of SBRT for oligometastasis have been identified. This manuscript will serve as a foundation for future clinical evaluations.
Johns Hopkins University, Baltimore, MD, USA.
Kristin J
KJ
Redmond
University of Washington School of Medicine, Seattle, WA, USA.
Simon S
SS
Lo
University of Florida, Jacksonville, FL, USA.
Roi
R
Dagan
Odette Cancer Centre-Sunnybrook Health Sciences, Toronto, Ontario, Canada.
Ian
I
Poon
University of Queensland, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
Matthew C
MC
Foote
Odette Cancer Centre-Sunnybrook Health Sciences, Toronto, Ontario, Canada.
Darby
D
Erler
Odette Cancer Centre-Sunnybrook Health Sciences, Toronto, Ontario, Canada.
Young
Y
Lee
Azienda Az. Ospedaliero-Universitaria di Modena, Dipartimento di Oncologia, Unita Operativa di Radioterapia, Modena, Italy.
Frank
F
Lohr
University Hospitals Seidman Cancer Center, Cleveland, OH, USA.
Tithi
T
Biswas
Department of Oncology, University of Turin, Turin, Italy.
Umberto
U
Ricardi
Odette Cancer Centre-Sunnybrook Health Sciences, Toronto, Ontario, Canada.
Arjun
A
Sahgal
D000465:Algorithms; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D006801:Humans; D064847:Multimodal Imaging / Q000379:methods; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy*; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D016896:Treatment Outcome; D047368:Tumor Burden
SBRT; oligometastatic cancer; stereotactic body radiation therapy; technical factors