When People with Opioid-Induced Constipation Speak: A Patient Survey.
Opioid-induced constipation (OIC) is a common consequence of opioid use for chronic pain. OIC creates problems for patients independent of their pain syndromes, in addition to threatening pain treatment effectiveness. Healthcare practitioners need to be alert to how patients talk about OIC so that it is not missed. Using a survey mechanism, we sought patient expressions of the personal impact OIC imposes on how they are able to live their lives and on meanings that symptom relief would produce.



We used an online survey asking adults with OIC about quality of life implications of OIC and focused on open-ended text responses to questions about personal impacts of straining and meanings attached to OIC symptom relief. Participants were from the US, Canada, UK, Germany, Sweden, and Norway.



A survey of 513 people with OIC produced 280 text responses concerning the impacts of straining on quality of life and 469 text responses on the meaning OIC symptom relief would confer. Text responses about the quality of life impacts of straining often included explicit descriptions conveying physical, psychological, or practical problems. Text responses about the meaning conferred from OIC symptom relief primarily concentrated around freedom from the constraints that OIC can impose.



Patients are willing and able to comment on the problems OIC cause them, using a variety of terms and phrases. Their comments concerning impacts on their lives will often refer to physical consequences, psychological effects, or practical implications. These insights provide healthcare practitioners guidance on how to engage patients about OIC.
Epstein Health, Woodcliff Lake, NJ, USA.
Robert S
RS
Epstein
Epstein Health, Woodcliff Lake, NJ, USA. rteagarden@epsteinhealth.com.
J Russell
JR
Teagarden
AstraZeneca, Cambridge, UK.
Ali
A
Cimen
AstraZeneca, Gaitherburg, MD, USA.
Mark
0000-0002-2779-730X
M
Sostek
AstraZeneca, Gaitherburg, MD, USA.
Tehseen
T
Salimi
D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D059350:Chronic Pain / Q000188:drug therapy*; D003248:Constipation / Q000139:chemically induced / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009293:Opioid-Related Disorders / Q000175:diagnosis / Q000523:psychology; D059408:Pain Management / Q000379:methods; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
D000701:Analgesics, Opioid
Gastroenterology; Opioid-induced constipation; Pain; Patient survey; Quality of life