Effects of phosphatidic acid supplementation on muscle thickness and strength in resistance-trained men.
The purpose of this study was to investigate the effects of phosphatidic acid (PA) supplementation on muscle thickness and strength following an 8 week supervised resistance-training program. Fifteen resistance trained men (22.8 ± 3.5 years; 80.6 ± 8.7 kg; 178.1 ± 5.6 cm; 14.6% ± 8.8% body fat) were randomly assigned to a group that either consumed 750 mg of PA or a placebo (PL). Testing was carried out before (PRE) and after (POST) training/supplementation for muscle thickness and strength. Muscle thickness of the rectus femoris (RF), vastus lateralis (VL), biceps brachii (BB), and triceps brachii (TB) muscles were measured via ultrasonography, along with 1 repetition maximum (1RM) of squat, deadlift, and bench press. Analysis of covariance (ANCOVA), using PRE values as the covariate, did not reveal any group differences for measures of muscle thickness in the RF (PA: 3.6% ± 5.2%; PL: 3.2% ± 4.2%, p = 0.97), VL (PA: 23.4% ± 18.1%, PL: 12.5% ± 15.4%, p = 0.37), BB (PA: 3.7% ± 6.4%, PL: 9.6% ± 12.4%, p = 0.86), or TB (PA: 15.1% ± 17.9%, PL: 10.7% ± 19.3%, p = 0.79). Likewise, no group differences were observed in changes in squat (PA: 8.4% ± 4.1%, PL: 8.1% ± 4.2%, p = 0.79), deadlift (PA: 10.1% ± 10.1%, PL: 8.9% ± 9.5%, p = 0.66), or bench press (PA: 5.7% ± 5.5%, PL: 5.1% ± 3.0%, p = 0.76) exercises. Collectively, however, all participants experienced significant (p < 0.05) improvements in each measure of muscle thickness and strength. Results of this study suggest that PA supplementation, in combination with a 3 days·week-1resistance-training program for 8 weeks, did not have a differential effect compared with PL on changes in muscle thickness or 1RM strength.
a Department of Health Professions, Hofstra University, Hempstead, NY 11549, USA.
Adam M
AM
Gonzalez
a Department of Health Professions, Hofstra University, Hempstead, NY 11549, USA.
Katie M
KM
Sell
a Department of Health Professions, Hofstra University, Hempstead, NY 11549, USA.
Jamie J
JJ
Ghigiarelli
a Department of Health Professions, Hofstra University, Hempstead, NY 11549, USA.
Christopher F
CF
Kelly
a Department of Health Professions, Hofstra University, Hempstead, NY 11549, USA.
Edward W
EW
Shone
a Department of Health Professions, Hofstra University, Hempstead, NY 11549, USA.
Matthew R
MR
Accetta
a Department of Health Professions, Hofstra University, Hempstead, NY 11549, USA.
Jamie B
JB
Baum
b Department of Exercise Science and Sport Management, Kennesaw State University, Kennesaw, GA 30144, USA.
Gerald T
GT
Mangine
D000328:Adult; D056352:Athletes; D054874:Athletic Performance; D004041:Dietary Fats / Q000008:administration & dosage / Q000009:adverse effects; D019587:Dietary Supplements / Q000009:adverse effects; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D024510:Muscle Development; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000254:growth & development; D010349:Patient Compliance; D058573:Performance-Enhancing Substances / Q000008:administration & dosage* / Q000009:adverse effects; D010712:Phosphatidic Acids / Q000008:administration & dosage* / Q000009:adverse effects; D015203:Reproducibility of Results; D055070:Resistance Training; D014463:Ultrasonography; D014891:Weight Lifting; D055815:Young Adult
D004041:Dietary Fats; D058573:Performance-Enhancing Substances; D010712:Phosphatidic Acids
croissance musculaire; entraînement contre résistance; ergogenic aid; facteur ergogène; muscle growth; nutritional supplement; phospholipid; phospholipide; resistance training; supplément nutritif