Young and Lean: Elimination of Senescent Cells Boosts Adaptive Thermogenesis.
Thermogenesis converts the chemical energy of nutrients into heat, and this is associated to improved metabolic performance. In a previous issue of Cell Metabolism, Berry et al. (2017) reported that the progenitors of thermogenic beige adipocytes lose functionality with aging, and this process can be reversed with strategies that eliminate senescent cells.
Madrid Institute for Advanced Studies (IMDEA) in Food, CEI UAM+CSIC, Madrid E28049, Spain. Electronic address: pablojose.fernandez@imdea.org.
Pablo J
PJ
Fernandez-Marcos
Spanish National Cancer Research Centre (CNIO), Madrid E28029, Spain. Electronic address: mserrano@cnio.es.
Manuel
M
Serrano
D017667:Adipocytes; D022722:Thermogenesis