[Prevalence and risk factors of vitamin D deficiency in healthy adults aged 18-65 years in northern France].
BACKGROUND
Screening and treatment of vitamin D deficiency are the subject of several publications. A lot of recognized risk factors have increased steadily, leading to the recognition of populations at risk. Despite their exposure to the same risk factors as other populations, there are no recommendations concerning healthy adults, a population rarely studied. To determine the prevalence of vitamin D deficiency in healthy adults aged 18-65 years residing in northern France and to search for correlated risk factors at 20ng/mL.


METHODS
Descriptive, prospective, single-center epidemiology study; 297 subjects studied in January and February, 2015. The prevalence of vitamin D deficiency was determined at three serum levels (10, 20 and 30ng/mL). A self-administered questionnaire was used to identify risk factors correlated with vitamin D deficiency (<20ng/mL).


RESULTS
25(OH) vitamin D serum level was strictly less than 30ng/mL in 92.3% of participants, strictly less than 20ng/mL in 75.1%, and strictly less than 10ng/mL in 27.9%. Male gender (P=0.0001), age (P=0.012), no vacations in sunny regions (P=0.03) and no intake of prescription vitamin supplements (P=0.002) were independent risk factors of vitamin D deficiency (<20ng/mL).


CONCLUSIONS
In our population, vitamin D deficiency is frequent in healthy adults and is often severe. A systematic screening and supplementation strategy would limit the development of many pathological complications and ensure good nutritional balance.
Service de médecine polyvalente, hôpital Saint-Vincent de-Paul, GHICL, boulevard de Belfort, BP 387, 59020 Lille cedex, France. Electronic address: deplanque.xavier@ghicl.net.
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Deplanque
Service de médecine polyvalente, hôpital Saint-Vincent de-Paul, GHICL, boulevard de Belfort, BP 387, 59020 Lille cedex, France.
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Wullens
Département statistique, Direction de la recherche clinique, hôpital Saint-Vincent-de-Paul, GHICL, boulevard de Belfort, BP 387, 59020 Lille cedex, France.
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Norberciak
D000293:Adolescent; D000328:Adult; D000368:Aged; D058070:Asymptomatic Diseases / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D014808:Vitamin D Deficiency / Q000097:blood / Q000453:epidemiology*; D055815:Young Adult
Adulte sain; Deficiency; Facteurs de risque; Healthy adult; Insuffisance; Prevalence; Prévalence; Risk factors; Vitamin D; Vitamine D