Single-shot edge illumination x-ray phase-contrast tomography enabled by joint image reconstruction.
Edge illumination x-ray phase-contrast tomography (EIXPCT) is an emerging x-ray phase-contrast tomography technique for reconstructing the complex-valued x-ray refractive index distribution of an object. Conventional image reconstruction approaches for EIXPCT require multiple images to be acquired at each tomographic view angle. This contributes to prolonged data-acquisition times and elevated radiation doses, which can hinder in vivo applications. In this work, a new "single-shot" method is proposed for joint reconstruction (JR) of the real and imaginary-valued components of the refractive index distribution from a tomographic data set that contains only a single image acquired at each view angle. The proposed method is predicated on a nonlinear formulation of the inverse problem that is solved by using a gradient-based optimization method. The method is validated and investigated using computer-simulated and experimental EIXPCT data sets.
Yujia
Y
Chen
Huifeng
H
Guan
Charlotte K
CK
Hagen
Alessandro
A
Olivo
Mark A
MA
Anastasio
D007091:Image Processing, Computer-Assisted / Q000379:methods*; D055620:Optical Phenomena; D014054:Tomography / Q000379:methods*; D014965:X-Rays