Inflammatory and Infectious Lesions of the Sinonasal Tract.
The sinonasal tract is frequently affected by nonneoplastic inflammatory diseases. Inflammatory lesions of the sinonasal tract can be divided into 3 main categories: chronic rhinosinusitis, which encompasses a heterogeneous group of entities, all of which result in mucosal inflammation with or without polyps-eosinophils; infectious diseases; and autoimmune diseases and vasculitides, which can result in midline necrosis and facial deformities. This article reviews the common inflammatory lesions of the sinonasal tract with emphasis on infectious diseases, vasculitis, iatrogenic, and diseases of unknown cause. Many of these lesions can result in midline destruction and result in facial deformity.
Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 6 Founders, Philadelphia, PA 19104, USA. Electronic address: Kathleen.Montone@uphs.upenn.edu.
Kathleen T
KT
Montone
Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 6 Founders, Philadelphia, PA 19104, USA.
Virginia A
VA
LiVolsi
D001327:Autoimmune Diseases / Q000175:diagnosis / Q000473:pathology; D003141:Communicable Diseases / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D009298:Nasal Polyps / Q000175:diagnosis / Q000473:pathology; D009668:Nose Diseases / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis; D012220:Rhinitis / Q000175:diagnosis / Q000473:pathology; D012852:Sinusitis / Q000175:diagnosis / Q000473:pathology; D014657:Vasculitis / Q000175:diagnosis / Q000473:pathology
Midline destructive disease; Rhinosinusitis; Sinonasal; Vasculitis