[Recurrence occurring ten years after the initial diagnosis of granulosa cell tumour of the ovary: about two cases and review of the literatur].
Granulosa Cell Tumors (GCT) of the ovary are rare tumors belonging to the group of sex cord stromal tumors. They represent 0.6 - 3% of all ovarian tumors and 5% of all malignant tumors. Two different types of GCT can be distinguished: juvenile granulosa cell tumor (JGT) which is characterized by its aggressive potential and adult granulosa cell tumor (AGT) which is the most common and the least aggressive type. GCT of the ovary usually develops recurrences within 5 years of initial diagnosis but they rarely develop local or peritoneal metastases. Although treatment options including surgery with or without chemotherapy or radiation have been reported in treating GCT relapses, there are no standardized protocols for the treatment of relapses. We here present our therapeutic strategy in the treatment of longterm relapses of GCT peritoneal carcinomatosis occurring in two patients 10 years after the initial diagnosis and a review of the literature.
Service de Radiothérapie, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Soufya
S
Majdoul
Service de Radiothérapie, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Nezha
N
Tawfiq
Service de Radiothérapie, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Zouhour
Z
Bourhaleb
Service d'Oncologie Médicale, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Nora
N
Naqos
Service d'Oncologie Médicale, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Amina
A
Taleb
Service de Radiothérapie, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Zineb
Z
Bouchbika
Service de Radiothérapie, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Nadia
N
Benchakroun
Service de Radiothérapie, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Hassan
H
Jouhadi
Service de Radiothérapie, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Souha
S
Sahraoui
Centre Mohammed VI de Traitement des Cancers, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Maroc.
Abdelatif
A
Benider
D000328:Adult; D005260:Female; D006106:Granulosa Cell Tumor / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D010534:Peritoneal Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D013997:Time Factors
Granulosa cell tumors of the ovary; late recedivism; treatment