[Glioblastoma, innovations in surgery].
One of the innovative principles in glioblastoma surgery consists in making the tumour fluorescent in order for it to be more easily visualised during the procedure. 5-aminolevulinic acid (5-ALA) undergoes an enzyme transformation, turning into another molecule, protoporphyrine IX (PPIX) whose property is fluorescence. It emits red light when it is stimulated by blue light.
Service de neurochirurgie oncologique et vasculaire, hôpital neurologique Pierre Wertheimer, CHU de Lyon, 59 Boulevard Pinel, 69500 Bron, France.
Thiebaud
T
Picart
Service de neurochirurgie oncologique et vasculaire, hôpital neurologique Pierre Wertheimer, CHU de Lyon, 59 Boulevard Pinel, 69500 Bron, France. Electronic address: jacques.guyotat@chu-lyon.fr.
Jacques
J
Guyotat
D001932:Brain Neoplasms / Q000451:nursing / Q000601:surgery*; D005909:Glioblastoma / Q000451:nursing / Q000601:surgery*; D006801:Humans; D007982:Levulinic Acids / Q000627:therapeutic use; D000072662:Margins of Excision; D019635:Neurosurgical Procedures / Q000379:methods / Q000451:nursing / Q000639:trends*; D025321:Surgery, Computer-Assisted / Q000379:methods / Q000451:nursing / Q000639:trends; D035703:Therapies, Investigational / Q000451:nursing / Q000639:trends; D000622:Aminolevulinic Acid
D007982:Levulinic Acids; D000622:Aminolevulinic Acid
chirurgie; excision; exérèse; fluorescence; glioblastoma; glioblastome; surgery; traitement; treatment