Relationship between yellow plaque grade and tissue protrusion after stent implantation: A coronary angioscopy study.
BACKGROUND
Tissue protrusion detected with optical coherence tomography after percutaneous coronary intervention using stents is one of the risk factors for early stent thrombosis. However, tissue protrusion features have not been described. The aim of this study was to compare tissue morphology at stented sites with or without tissue protrusion by using coronary angioscopy.


METHODS
Using optical coherence tomography and coronary angioscopy, we assessed 42 patients [31 men, 11 women; age, 70.7±7.4years; acute coronary syndrome (ACS), n=19; effort angina pectoris (EAP), n=23] after stenting.


RESULTS
Twenty patients had tissue protrusion. ACS patients had a higher incidence of tissue protrusion than EAP patients (70.0% vs 29.4%; p=0.002). The plaque at the protrusion site had higher-grade yellow plaque with thrombus than those without protrusion (2.35±0.67 vs 1.40±0.67; p<0.001). The plaque at protrusion sites developed more thrombi (60.0% vs 22.7%; p=0.041).


CONCLUSIONS
Tissue protrusion after stent implantation was associated with high-grade yellow plaque with thrombi.
Department of Cardiovascular Medicine, Ehime Prefectural Imabari Hospital, Imabari, Japan. Electronic address: mmyrb0807@gmail.com.
Toru
T
Miyoshi
Department of Cardiovascular Medicine, Ehime Prefectural Imabari Hospital, Imabari, Japan.
Hideo
H
Kawakami
Department of Cardiovascular Medicine, Ehime Prefectural Imabari Hospital, Imabari, Japan.
Fumiyasu
F
Seike
Department of Cardiovascular Medicine, Ehime Prefectural Imabari Hospital, Imabari, Japan.
Akira
A
Oshita
Department of Cardiovascular Medicine, Ehime Prefectural Imabari Hospital, Imabari, Japan.
Hiroshi
H
Matsuoka
D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging / Q000601:surgery*; D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000601:surgery*; D017546:Angioscopy; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention; D058226:Plaque, Atherosclerotic / Q000000981:diagnostic imaging / Q000209:etiology*; D012307:Risk Factors; D015607:Stents / Q000009:adverse effects*; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*; D041623:Tomography, Optical Coherence
Coronary angioscopy; Tissue protrusion; Yellow plaque