Hemodynamics study of a multilayer stent for the treatment of aneurysms.
BACKGROUND
The changes of hemodynamics caused by the implantation of multilayer stent (MS) have significant effects for aneurysm sac.


METHODS
Comparisons of 3D numerical models with/without a MS in an abdominal aortic aneurysm with a 90° branch vessel were numerically studied from the viewpoint of hemodynamics.


RESULTS
The results showed that: (1) The flow fields and Wall Shear Stress (WSS) are changed dramatically after MS implantation. The velocity of the blood flow in aneurysm sac decreases significantly and the regions of low-WSS increase. These help thrombus formation; (2) The pressure in aneurysm slightly decreases and keeps close to the normal level of blood pressure, however the risk of aneurysm enlargement or even rupture still exists; (3) The flux and the velocity in branch artery are reduced by about half after MS implantation. Due to the implantation of MS, the changes in the flow field causes the decrease of pressure/WSS in aneurysm sac and the blood flow in branch vessel.


CONCLUSIONS
The implantation of MS into abdominal artery results in more low-WSS regions inside aneurysm which induces thrombus formation. The pressure is reduced slightly means the risk of aneurysm rupture exists.
School of Manufacturing Science and Engineering, Sichuan University, 610065, Chengdu, China.
Yan
Y
Xiong
Department of Applied Mechanics, Sichuan University, 610065, Chengdu, China.
Xuhong
X
Wang
Department of Applied Mechanics, Sichuan University, 610065, Chengdu, China. scubme@aliyun.com.
Wentao
W
Jiang
Department of Applied Mechanics, Sichuan University, 610065, Chengdu, China.
Xiaobao
X
Tian
Department of Applied Mechanics, Sichuan University, 610065, Chengdu, China.
Qingyuan
Q
Wang
School of Biological Science and Medical Engineering, Beihang University, 100191, Beijing, China.
Yubo
Y
Fan
Department of Applied Mechanics, Sichuan University, 610065, Chengdu, China. yu_chen@scu.edu.cn.
Yu
Y
Chen
D000465:Algorithms; D017542:Aneurysm, Ruptured / Q000503:physiopathology / Q000601:surgery; D017544:Aortic Aneurysm, Abdominal / Q000503:physiopathology* / Q000601:surgery*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D003198:Computer Simulation; D006439:Hemodynamics; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008955:Models, Cardiovascular; D033081:Shear Strength; D015607:Stents; D013314:Stress, Mechanical; D013927:Thrombosis
Aorticaneurysm; Blood flow; Multilayer stent; Pressure; WSS