Strong family history and early onset of schizophrenia: about 2 families in Northern Nigeria.
Schizophrenia is a highly heritable psychotic disorder and high genetic loading is associated with early onset of the disease. The outcome of schizophrenia has also been linked with the age of onset as well as the presence of family history of the disease. Therefore families with patients with early onset Schizophrenia are subpopulations for genetic studies. We present 2 families with heavy genetic loading who have adolescents with schizophrenia.
Federal Neuropsychiatric Hospital, Barnawa Kaduna, Nigeria.
Folorunsho Tajudeen
FT
Nuhu
Department of Paediatrics, Ahmadu Bello University Teaching Hospital, Zaria Nigeria.
Edwin Ehi
EE
Eseigbe
Department of Behavioural Science, University of Ilorin Teaching Hospital, Ilorin Nigeria.
Baba Awoye
BA
Issa
Federal Neuropsychiatric Hospital, Barnawa Kaduna, Nigeria.
Michael Omeiza
MO
Gomina
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D002648:Child; D005192:Family Health; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D009549:Nigeria; D012559:Schizophrenia / Q000453:epidemiology* / Q000235:genetics
Schizophrenia; age of onset; genetic loading; outcome