Postoperative keratitis due toPaecilomyces: a rare pediatric case.
Fungal infections likePaecilomyces keratitishave emerged in childhood recently. The diagnosis and treatment ofPaecilomyces keratitisis difficult and the outcome is usually poor. Corneal culture should be performed on fungal media such as Sabouraud glucose neopeptone agar (SDA) as soon as possible for diagnosis. We report a rare case ofPaecilomyces keratitisin an immunocompetent child, which was unresponsive to amphotericin B. The case was managed by a multidisciplinary approach involving the departments of ophthalmology, microbiology and pediatric infectious diseases. We want to draw attention once again that fungal keratitis caused by unusual agents are increasing. Physicians should consider fungal causes of keratitis, in patients with some predisposing factors like ocular surgery and prolonged use of topical corticosteroids.
Istanbul University, Istanbul Faculty of Medicine, Department of Ophthalmology, Pendik, Istanbul, Turkey.
Ebru
E
Toker
The Council of Forensic Medicine, Department of Microbiology, Istanbul, Turkey.
Nihan
N
Ziyade
Marmara University Medical Faculty, Department of Pediatric Infectious Diseases, Pendik, Istanbul, Turkey.
Serkan
S
Atici
Marmara University Medical Faculty, Department of Pediatric Infectious Diseases, Pendik, Istanbul, Turkey.
Kepenekli Kadayifçi
KK
Eda
Bezmialem Vakif University, Department of Pediatric Infectious Diseases, Istanbul, Turkey.
Özden
Ö
Türel
Boston Childrens Hospital, Department of Pediatric/Urgent Care, USA.
Demet
D
Toprak
Istanbul University, Istanbul Faculty of Medicine, Department of Ophthalmology, Pendik, Istanbul, Turkey.
Merih
M
Oray
Marmara University Medical Faculty, Department of Microbiology, Istanbul, Turkey.
Nilgün
N
Cerikcioglu
Marmara University Medical Faculty, Department of Pediatric Infectious Diseases, Pendik, Istanbul, Turkey.
Ahmet
A
Soysal
Marmara University Medical Faculty, Department of Pediatric Infectious Diseases, Pendik, Istanbul, Turkey.
Mustafa
M
Bakir
D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D003315:Cornea / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D007634:Keratitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D013508:Ophthalmologic Surgical Procedures / Q000009:adverse effects; D010143:Paecilomyces / Q000302:isolation & purification*; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology
D000935:Antifungal Agents; D000666:Amphotericin B
Fungal infection; paecilomyces; voriconazole