Utility of Duranta, a wireless patch-type electrocardiographic monitoring system developed in Japan, in detecting covert atrial fibrillation in patients with cryptogenic stroke: A case report.
BACKGROUND
Subcutaneous implantable electrocardiographs are highly effective in detecting covert atrial fibrillation (AF) in cryptogenic stroke. However, these invasive devices are not indicated for all cryptogenic stroke patients, and noninvasive improvements over conventional Holter-type ambulatory electrocardiography are needed. We evaluated the clinical application and effectiveness of Duranta (ImageONE Co., Ltd.), a wireless patch-type electrocardiographic monitoring system developed in Japan for chronically ill patients or home-based patients at the end of life. A Duranta device was used to detect covert AF in patients with acute ischemic stroke of undetermined source with no sign of AF during cardiographic monitoring ≥24 hours postadmission.


METHODS
A 72-year-old man with severe aortic stenosis was admitted to our hospital with dysarthria and right upper limb weakness. Diffusion-weighted plain head magnetic resonance imaging (MRI) showed acute cerebral infarctions across the left middle cerebral artery territory. Twelve-lead electrocardiography, Holter-type ambulatory electrocardiography, and cardiographic monitoring for ≥24 hours revealed no AF, indicating a probable diagnosis of artery-to-artery embolism following left common carotid artery stenosis detected by carotid ultrasound imaging and cerebral angiography.


METHODS
However, because of high blood brain natriuretic peptide (BNP) and valvular heart disease, continuous monitoring using Duranta was performed from the 2nd to 13th days after onset to exclude possible cardioembolic stroke. Waveform and heart rate trend graph analysis showed paroxysmal AF (PAF) occurred on the 5th and 9th days after onset. PAF did not occur at any other time during the observation period. The quality of the cardiograms sufficed for analysis and diagnosis of AF. The lightweight compact device can be placed quickly with no movement restriction. These features and our findings show the usefulness of the Duranta device for long-term continuous monitoring.


CONCLUSIONS
A noninvasive wireless patch-type electrocardiographic monitoring system, Duranta, placed at the precordium, was useful in detecting covert AF in cryptogenic stroke patients, warranting further investigation.
Department of Neurology, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan.
Hisanao
H
Akiyama
Saki
S
Nukui
Takashi
T
Araga
Masashi
M
Hoshino
Keita
K
Tanaka
Satoru
S
Kashima
Rie
R
Sasaki
Kenji
K
Uchino
Yasuhiro
Y
Hasegawa
D000208:Acute Disease; D000368:Aged; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging; D001281:Atrial Fibrillation / Q000150:complications* / Q000175:diagnosis*; D002545:Brain Ischemia / Q000209:etiology*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging; D015716:Electrocardiography, Ambulatory / Q000295:instrumentation*; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood; D020521:Stroke / Q000209:etiology*
D020097:Natriuretic Peptide, Brain