Metaphase Spindle Assembly.
A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells.
Laboratory of Chemistry and Cell Biology, the Rockefeller University, New York, NY 10065, USA. kapoor@mail.rockefeller.edu.
Tarun M
TM
Kapoor
cell division; chromosome; dynein; kinesin; metaphase; microtubules; mitosis