An extramedullary plasmacytoma in the kidney of a 14-year-old girl: Case report and review of the literature.
BACKGROUND
Extramedullary plasmacytoma (EMP) a rare plasma cell disorder and is frequently associated with plasma cell bone marrow infiltration. Most EMPs involve mucosal lymphoid tissue, especially in the nasopharyngeal area, respiratory tract, and head and neck region. Primary involvement of the kidney is exceedingly rare.


METHODS
A 14-year-old girl was admitted in our hospital with intermittent right upper quadrant pain for 1 month and recent (1 day) progressive deterioration. There was a mass found by ultrasonography in the right kidney and subsequent abdominal computed tomography scan revealed a 3 cm mass within the right kidney.


METHODS
Pathology revealed typical histology of plasmacytoma and immunohistochemistry revealed the expression of CD138, CD45, vimentin, and Kappa light chain.


METHODS
The patient successfully underwent radical nephrectomy with an uneventful recovery. She received no chemotherapy or radiotherapy after surgery.


RESULTS
There was no recurrence or metastasis during a 22-month follow-up.


CONCLUSIONS
Our case study demonstrated that renal EMP with a relatively indolent clinical course, if detected at an early stage, can be treated by radical nephrectomy without adjuvant therapy. Generally, the clinical outcome and prognosis of EMP are favorable.
Department of Urology, Affiliated Hospital of Binzhou Medical University, Binzhou Department of Urology, Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.
Yan-Hui
YH
Mei
Jian-Peng
JP
Yu
Gang
G
Li
D000293:Adolescent; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D010954:Plasmacytoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery