Complete genome sequence of Serratia sp. YD25 (KCTC 42987) presenting strong antagonistic activities to various pathogenic fungi and bacteria.
Serratia sp. YD25 (KCTC 42987) was originally isolated from rhizosphere soil in a continuous cropping tobacco-planting farm. Here, we show that its metabolites efficiently suppress the growth of various important pathogenic fungi and bacteria, causing infection in both plants and humans. In addition, Serratia sp. YD25 has a special trait of simultaneous production of both serrawettin W2 and prodigiosin, two important bioactive secondary metabolites produced by Serratia strains. Such co-production has not been reported in other Serratia strains. The complete genome sequence of Serratia sp. YD25 is presented, which is valuable for further exploration of its biotechnological applications in agriculture and medicine. The genome sequence reported here is also useful for understanding the unique regulatory mechanisms underlying biosynthesis of active compounds.
National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi'an 710119, PR China.
Chun
C
Su
National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi'an 710119, PR China.
Yibo
Y
Liu
National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi'an 710119, PR China. Electronic address: sunyan@snnu.edu.cn.
Yan
Y
Sun
National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi'an 710119, PR China. Electronic address: lizhi@snnu.edu.cn.
Zhi
Z
Li
D000900:Anti-Bacterial Agents / Q000096:biosynthesis; D000935:Antifungal Agents / Q000378:metabolism; D001424:Bacterial Infections; D016680:Genome, Bacterial; D006801:Humans; D009181:Mycoses; D010935:Plant Diseases; D012705:Serratia / Q000235:genetics* / Q000378:metabolism
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents
Antimicrobial activity; Complete genome sequence; Secondary metabolites; Serratia sp. YD25 (KCTC 42987)