Measurement of and Factors Associated with the Anterior Chamber Volume in Healthy Chinese Adults.
Purpose. To measure the anterior chamber volume (ACV) and determine factors associated with the ACV in healthy Chinese adults.Methods. In this cross-sectional study, we used swept-source optical coherence tomography (SS-OCT) to measure ACV and other anterior segment parameters. Factors associated with ACV were also determined.Results. A total of 313 healthy Chinese adults were enrolled. The anterior segment parameters, including ACV, could be measured by SS-OCT with excellent repeatability and reproducibility. There was a significant difference between the horizontal and vertical anterior chamber widths (ACW) (P< 0.05), with a mean difference of 390μm. The ACV (mean 153.83 ± 32.42 mm3) was correlated with most of the anterior segment parameters, especially anterior chamber depth (ACD), which accounted for about 85% of the variation of ACV. Most of the anterior segment parameters were significantly correlated with age, and the relative changes in ACV and ACD were greatest in subjects aged 41-50 years.Conclusion. ACV was correlated with most of the anterior segment parameters measured in this study, particularly ACD. The relatively large difference between horizontal and vertical ACW suggests that the ACV could and should be measured using multiple OCT scans.
Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai, Shanghai 200031, China.
Yuan
0000-0002-0178-990X
Y
Zong
Department of Ophthalmology, The Central Hospital of Zaozhuang Mining Group, Zaozhuang 277800, China.
Qian
Q
Xu
Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai, Shanghai 200031, China; Department of Ophthalmology, People's Hospital of Shanghai, No. 5, Shanghai 200240, China.
Chunhui
0000-0001-7857-9292
C
Jiang
Department of Ophthalmology, People's Hospital of Shanghai, No. 5, Shanghai 200240, China.
Haohao
0000-0003-1848-2354
H
Zhu
Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai, Shanghai 200031, China.
Jian
J
Yu
Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai, Shanghai 200031, China.
Xinghuai
0000-0002-4440-1389
X
Sun