[Zika virus infection in pregnancy, fetal and neonatal impact].
Zika virus (ZV) is an arbovirus transmitted by Aedes aegypti and A. albopictus. The neurotropic profile of this virus is known since 1952. The main finding related to ZV in America is microcephaly. Two hypotheses are tested on its involvement in the central nervous system: its neurotropic feature and the direct effect of ZV on the placenta. Malformations and clinical findings on fetal development comprise congenital Zika syndrome. RT-PCR and serology (IgM) are useful for definitive diagnosis. However, we should keep in mind first that the viremia in pregnant women can stay for a longer period of time, and second, a positive IgM for Zika should be properly interpreted in an endemic area to other flavivirus. It is suggested to be part of TORCHS-Z complex the ZV infection in endemic areas.
Universidad de Cartagena, Cartagena, Colombia.
Wilfrido
W
Coronell-Rodríguez
Universidad de Cartagena, Cartagena, Colombia.
Cindy
C
Arteta-Acosta
Universidad el Bosque, Bogotá, Colombia.
M Alejandra
MA
Suárez-Fuentes
UCI Caribe, Clínica Santa Cruz de Bocagrande, Cartagena, Colombia.
M Cecilia
MC
Burgos-Rolon
Universidad de Cartagena, Cartagena, Colombia.
M Teresa
MT
Rubio-Sotomayor
Universidad de Cartagena, Cartagena, Colombia.
Michelle
M
Sarmiento-Gutiérrez
Universidad de Cartagena, Cartagena, Colombia.
Carlos
C
Corzo-Díaz
D000818:Animals; D005260:Female; D006801:Humans; D008831:Microcephaly / Q000821:virology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000821:virology*; D000071243:Zika Virus Infection / Q000150:complications / Q000175:diagnosis / Q000821:virology