Comparison of low-dose coronary artery calcium scoring using low tube current technique and hybrid iterative reconstruction vs. filtered back projection.
BACKGROUND
We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP).


METHODS
We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP.


RESULTS
No significant difference between full and low dose CT in Agatston score 138.2±360.6 vs. 137.3±356.4 (p=0.272) or calcium mass score 19±48.3 vs. 18.7±49 (p=0.8), respectively. Bland-Altman analysis showed no systematic bias. Calcium volume difference was statistically significant 57.2±134 vs. 55.1±130.2 (p=0.001).


CONCLUSIONS
Low dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium mass quantification as compared to full dose FBP.
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: sulaimannada@gmail.com.
Nada
N
Sulaiman
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: jeanette.soon@gmail.com.
Jeanette
J
Soon
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: jongknpark@gmail.com.
Jong Kwan
JK
Park
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: chris.naoum@gmail.com.
Christopher
C
Naoum
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: sh_kueh@hotmail.com.
Shaw-Hua
SH
Kueh
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: phil.blanke@gmail.com.
Philipp
P
Blanke
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: darramurphy@me.com.
Darra
D
Murphy
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: ellisjen19@gmail.com.
Jennifer
J
Ellis
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: cjhague75@gmail.com.
Cameron J
CJ
Hague
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: jleipsic@providencehealth.bc.ca.
Jonathon
J
Leipsic
D000328:Adult; D000368:Aged; D000465:Algorithms; D002118:Calcium / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000378:metabolism / Q000473:pathology*; D003331:Coronary Vessels / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*
D002118:Calcium
Agatston score; Computed tomography; Coronary artery calcium score; Filtered back projection; Iterative reconstruction; Noise index