[The use of MALDI-TOF MS for direct identification of bacteria in clinical specimens].
MALDI-TOF MS is a method enabling rapid identification of bacteria. This is also important for early initiation of adequate antibiotic therapy in patients with infections. In this review, various methods for direct detection of bacteria in clinical specimens are described. The fundamental part deals with direct identification of bacteria from positive blood cultures. Attention is also paid to identification of bacteria from urine and cerebrospinal fluid. Finally, reliability of the methods is mentioned in comparison with conventional methods.
Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Czech Republic, e-mail: radka.tarabova@gmail.com.
Radka
R
Tarabová
Jan
J
Bardoň
D001419:Bacteria / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000382:microbiology* / Q000652:urine; D006801:Humans; D015203:Reproducibility of Results; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013997:Time Factors