Designing β Cells.
Diabetes is a growing epidemic, and many patients depend on insulin injections to control the disease and minimize long-term complications. In a recent manuscript published in Science, Xie et al. (2016) generate insulin-producing cells from a somatic embryonic kidney cell line through minimal genetic modification capable of regulating glucose levels in diabetic mice.
Diabetes Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: mhebrok@diabetes.ucsf.edu.
Matthias
M
Hebrok
D000818:Animals; D001786:Blood Glucose; D002460:Cell Line; D003921:Diabetes Mellitus, Experimental; D006801:Humans; D007328:Insulin / Q000235:genetics; D050417:Insulin-Secreting Cells; D051379:Mice
D001786:Blood Glucose; D007328:Insulin