Anterior Skull Base Glomangioma-Induced Osteomalacia.
Oncogenic osteomalacia (OO) is an uncommon but treatable cause of osteomalacia related to tumor production of FGF23, usually caused by benign mesenchymal neoplasms. Paranasal sinus glomangiomas are a rare cause of OO, with only one previously reported case. Here we describe a second case (first reported in English) of paranasal sinus glomangioma-induced osteomalacia in a 42-year-old man. He presented with weakness and multiple spontaneous fractures, and was found to have an ethmoid sinus glomangioma with intracranial extension. The tumor was removed via endoscopic endonasal approach to the anterior skull base, which resulted in complete resolution of symptoms and no further evidence of disease 1 year postoperatively.
Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States.
Malia S
MS
Gresham
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, United States.
Steven
S
Shen
Division of Neurological Surgery, Department of Neurosurgery, Houston Methodist Hospital, Houston, Texas, United States.
Yi J
YJ
Zhang
Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States.
Kelly
K
Gallagher
glomangioma; glomus tumor; oncogenic osteomalacia; paranasal sinus tumor