Congenital diaphragmatic hernia: pathogenesis, prenatal diagnosis and management - literature review.
Congenital diaphragmatic hernia (CDH) is a developmental discontinuity of the diaphragm. It allows abdominal viscera to herniate into the chest and leads to lung hypoplasia. Congenital diaphragmatic hernia is one of the most severe birth defects, with extremely high neonatal mortality. This paper presents a review of the available literature on prenatal diagnosis, management and treatment options for CDH. In selected cases, a prenatal procedure to improve neonatal survival is possible. The authors of this manuscript believe their work might contribute to a better understanding of congenital diaphragmatic hernia and patient selection for the FETO (fetal endoscopic tracheal occlusion) surgery or expectant management.
1stDepartment of Obstetrics and Gynecology, Medical University of Warsaw, Poland. pkosinski.mail@gmail.com.
Przemysław
P
Kosiński
Mirosław
M
Wielgoś
D000015:Abnormalities, Multiple; D019468:Disease Management; D005260:Female; D046128:Fetal Therapies / Q000379:methods*; D005332:Fetoscopy; D005333:Fetus / Q000601:surgery*; D065630:Hernias, Diaphragmatic, Congenital / Q000000981:diagnostic imaging / Q000196:embryology / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D014132:Trachea / Q000601:surgery*; D016216:Ultrasonography, Prenatal
FETO procedure; congenital diaphragmatic hernia; lung hypoplasia; tracheal balloon occlusion