FAMILIAL LARYNGEAL WEB IN THREE GENERATIONS WITH PROBABLE AUTOSOMAL DOMINANT TRANSMISSION.
We report a family with congenital anterior laryngeal web in three males and two females in three successive generations. The maternal grandmother of our proband had a spontaneous occurrence of the web, which subsequently was transmitted in a probable autosomal dominant pattern. A left vocal cord paralysis was documented in two of the affected members.
Division of Genetics, (SMS, MGB, JAP), Department of Pediatrics (JWC), and Department of Otolaryngology (JLN), Vanderbilt University School of Medicine, Nashville, TN and Bowling Green, KY (WTM).
Stephen M
SM
Strakowski
Division of Genetics, (SMS, MGB, JAP), Department of Pediatrics (JWC), and Department of Otolaryngology (JLN), Vanderbilt University School of Medicine, Nashville, TN and Bowling Green, KY (WTM).
Merlin G
MG
Butler
Division of Genetics, (SMS, MGB, JAP), Department of Pediatrics (JWC), and Department of Otolaryngology (JLN), Vanderbilt University School of Medicine, Nashville, TN and Bowling Green, KY (WTM).
James W
JW
Cheek
Division of Genetics, (SMS, MGB, JAP), Department of Pediatrics (JWC), and Department of Otolaryngology (JLN), Vanderbilt University School of Medicine, Nashville, TN and Bowling Green, KY (WTM).
William T
WT
Moore
Division of Genetics, (SMS, MGB, JAP), Department of Pediatrics (JWC), and Department of Otolaryngology (JLN), Vanderbilt University School of Medicine, Nashville, TN and Bowling Green, KY (WTM).
James L
JL
Netterville
Division of Genetics, (SMS, MGB, JAP), Department of Pediatrics (JWC), and Department of Otolaryngology (JLN), Vanderbilt University School of Medicine, Nashville, TN and Bowling Green, KY (WTM).
John A
JA
Phillips
congenital anterior glottic web; inheritance; left vocal cord paralysis