Brain Glucose Metabolism in Parry-Romberg Syndrome.
Parry-Romberg syndrome is a rare disorder characterized by a progressive facial hemiatrophy of the skin, subcutaneous tissue, musculature, bone, and cartilage. It is often associated with neurological symptoms such as trigeminal neuropathy, paresthesia of the face, migraine, and seizures and can be paired with ocular problems and ipsilateral progressive body atrophy. Here, we present a young woman with progressive facial hemiatrophy, who was referred for FDG-PET/CT. Hypometabolism was observed in the left cingulate and postcentral gyrus, left cerebellum, and right basal ganglia. Hypometabolism may be observed before anatomical changes and therefore facilitate early diagnosis.
From the Departments of *Nuclear Medicine, and †Neurology, University Hospital of Cologne, Cologne; and ‡Department of Neurology, Heilig Geist-Hospital, Cologne, Germany.
Klara
K
Uhrhan
Monika
M
Rabenstein
Carsten
C
Kobe
Alexander
A
Drzezga
Gereon R
GR
Fink
Lothar
L
Burghaus
D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism; D005150:Facial Hemiatrophy / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals; D055815:Young Adult
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18