A preliminary study on the potential ofMycoplasma pneumoniaeto induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia.
BACKGROUND
This study aimed to explore the cellular morphology of respiratory epithelium inMycoplasma pneumonia(MpP) patients.


METHODS
The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed.


RESULTS
Compared with the CAP group, cellular dysplasia in respiratory tract epithelial brushings was significantly greater in MpP patients (P= 0.033).


CONCLUSIONS
Unique biological characteristics and mechanisms of pathogenesis ofMycoplasma pneumoniae(Mp) may result in dyskaryotic changes in respiratory epithelium in adult MpP.
Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China.
Shu-Chang
SC
An
Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.
Dong-Hong
DH
Yang
Department of Radiology, First Hospital of Tsinghua University, Beijing, China.
Chao-Feng
CF
Luo
Department of Pathology, First Hospital of Tsinghua University, Beijing, China.
Xin
X
Chen
Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China.
Guo-Tian
GT
Liu
Department of Pathology, First Hospital of Tsinghua University, Beijing, China.
Yan
Y
Weng
Department of Radiology, First Hospital of Tsinghua University, Beijing, China.
Jing-Zhe
JZ
Liu
Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.
Ying
Y
Shang
Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China.
Rui-Qin
RQ
Wang
Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.
Zhan-Cheng
ZC
Gao
Cellular dysplasia; Mycoplasma pneumonia; community-acquired pneumonia