Acute urinary retention secondary to urethral involvement of granulomatosis with polyangiitis.
Granulomatosis with polyangiitis (GPA, formerly Wegener's granulomatosis) is a systemic necrotizing vasculitis of small- and medium-sized blood vessels, primarily affecting the upper and lower respiratory tracts, as well as the kidneys. Urogenital manifestations of GPA are exceedingly rare and usually respond well to systemic immunosuppressive therapy. Here, we present a case of a 36-year-old female presenting with acute urinary obstruction secondary to urethral GPA involvement in the immediate postpartum period. Special consideration should be given to ruling out malignancy in all patients with a history of GPA and urethral lesions, especially when there is a history of cyclophosphamide treatment.
Department of Surgery, Division of Urology, University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada.
Patrick T
PT
Anderson
Department of Medicine, Division of Rheumatology; Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, London, ON, Canada.
Stephanie
S
Gottheil
Department of Pathology; Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, London, ON, Canada.
Manal
M
Gabril
Department of Medicine, Division of Rheumatology; Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, London, ON, Canada.
Lillian
L
Barra
Department of Surgery, Division of Urology; Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, London, ON, Canada.
Nicholas
N
Power