Predictive Factors for Good Outcome and Mortality After Stent-Retriever Thrombectomy in Patients With Acute Anterior Circulation Stroke.
OBJECTIVE
Predictive factors associated with stent-retriever thrombectomy for patients with acute anterior circulation stroke remain to be elucidated. This study aimed to investigate clinical and procedural factors predictive of good outcome and mortality after stent-retriever thrombectomy in a large cohort of patients with acute anterior circulation stroke.


METHODS
We analyzed clinical and procedural data in 335 patients with acute anterior circulation stroke treated with stent-retriever thrombectomy. A good outcome was defined as a modified Rankin Scale score of 0 to 2 at 3 months. The associations between clinical, imaging, and procedural factors and good outcome and mortality, respectively, were evaluated using logistic regression analysis.


RESULTS
Using multivariate analysis, age (odds ratio [OR], 0.965; 95% confidence interval [CI], 0.944-0.986;P=0.001), successful revascularization (OR, 4.658; 95% CI, 2.240-9.689;P<0.001), parenchymal hemorrhage (OR, 0.150; 95% CI, 0.049-0.460;P=0.001), and baseline NIHSS score (OR, 0.908; 95% CI, 0.855-0.965;P=0.002) were independent predictors of good outcome. Independent predictors of mortality were age (OR, 1.043; 95% CI, 1.002-1.086;P=0.041), successful revascularization (OR, 0.171; 95% CI, 0.079-0.370;P<0.001), parenchymal hemorrhage (OR, 2.961; 95% CI, 1.059-8.276;P=0.038), and a history of previous stroke/TIA (OR, 3.124; 95% CI, 1.340-7.281;P=0.008).


CONCLUSIONS
Age, revascularization status, and parenchymal hemorrhage are independent predictors of both good outcome and mortality after stent retriever thrombectomy for acute anterior circulation stroke. In addition, NIHSS score on admission is independently associated with good outcome, whereas a history of previous stroke is independently associated with mortality.
Department of Radiology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea.
Woong
W
Yoon
Department of Radiology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea.
Seul Kee
SK
Kim
Department of Neurology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea.
Man Seok
MS
Park
Department of Radiology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea.
Byung Hyun
BH
Baek
Department of Radiology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea.
Yun Young
YY
Lee
Brain infarction; Mortality; Outcome; Prognosis; Thrombectomy