Incidence and predictors of surgical site infection in Ethiopia: prospective cohort.
Surgical site infections are commonest nosocomial infections and responsible for considerable morbidity and mortality as well as increased hospitalizations and treatment cost related to surgical operations. The aim of this study was to determine incidence and predictors of surgical site infections at surgical ward of Hawassa University Referral Hospital, Southern Ethiopia.



We performed prospective study involving 105 patients that undergone major surgical procedure at Hawassa University Referral Hospital from March 2 to May 2, 2015. Data were extracted from paper based medical charts, operational and anesthesia note, by direct observation and patients' interview. All patients were followed daily before, during and after operation for 30 days starting from the date of operation. Data were analyzed using Statistical Package for Social Science (SPSS) for window version 20.0 software. Predictors of Surgical site infections were identified using multivariable logistic regression model. P-value less than 0.05 was considered to be statistically significant.



We studied 105 patients. Sixty four patients (61%) were males. The mean age of the patients was 30.85 ± 17.72 years. The mean Body Mass Index (BMI) was 21.6 ± 4 kg/m2. Twenty patients (19.1%) developed surgical site infections. Age greater than 40 years, AOR = 7.7(95% CI [1.610-40.810 p = 0.016,]), preoperative hospital stay more than 7 days, AOR = 22.4(95% CI [4.544-110.780, p = 0.001]), duration of operation more than 1 hour, AOR = 8.01(95% CI [1.562-41.099, p = 0.013]) and administering antimicrobial prophylaxis before 1 hour of operation, AOR = 11.1 (95% CI [1.269-75.639, p = 0.014]) were independent predictors for surgical site infections.



Surgical site infection is relatively high.
Hawassa College of Health Sciences, Hawassa, Ethiopia.
Tamrat
T
Legesse Laloto
Department of Epidemiology, Faculty of Public Health, Institute of Health Sciences, Jimma University, Jimma, Ethiopia.
Desta
D
Hiko Gemeda
Pharmacology and Clinical Pharmacy Department, School of Pharmacy, Addis Ababa University, Jimma, Ethiopia. sadhussen@yahoo.com.
Sadikalmahdi Hussen
SH
Abdella
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D019072:Antibiotic Prophylaxis / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003428:Cross Infection / Q000453:epidemiology; D013505:Digestive System Surgical Procedures; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D007223:Infant; D007902:Length of Stay / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D013517:Otorhinolaryngologic Surgical Procedures; D011446:Prospective Studies; D012307:Risk Factors; D013514:Surgical Procedures, Operative; D013530:Surgical Wound Infection / Q000453:epidemiology*; D013520:Urologic Surgical Procedures; D055815:Young Adult
Antimicrobial prophylaxis; Ethiopia; Predictors; Surgical site infection