Absorption of Irrigation Fluid During Thulium Laser Vaporization of the Prostate.
To assess the prevalence and extent of irrigation fluid absorption during thulium laser vaporization of the prostate.



Fifty-four patients undergoing thulium laser vaporization of the prostate were prospectively included into the trial at a tertiary referral center. Isotonic saline containing 1% ethanol was used for intraoperative irrigation. Absorption of irrigation fluid was measured periodically during the operation using the expired breath ethanol technique. Among others, intra- and postoperative changes in biochemical and hematological laboratory findings were assessed.



Absorption of irrigation fluid was detected in 7 out of 54 (13%) patients with a median absorption volume of 265 mL (227-615). No significant differences of intra- and postoperative blood parameters were observed between absorbers and nonabsorbers. No risk factor (i.e., age, prostate size, surgery duration, applied energy, and amount of irrigation fluid) for the occurrence of fluid absorption could be identified.



Absorption of irrigation fluid also occurs during thulium laser vaporization of the prostate and should be kept in mind, especially in patients at a high cardiovascular risk. However, compared with previously assessed resection and vaporization techniques, thulium vaporization might have a favorable safety profile regarding fluid absorption.
1 Department of Urology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Gautier
G
Müllhaupt
1 Department of Urology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Dominik
D
Abt
1 Department of Urology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Livio
L
Mordasini
1 Department of Urology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Olivia
O
Köhle
1 Department of Urology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Daniel S
DS
Engeler
2 Department of Anesthesiology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Andreas
A
Lüthi
3 Clinical Trials Unit, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Rafael
R
Sauter
1 Department of Urology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Hans-Peter
HP
Schmid
1 Department of Urology, Cantonal Hospital St. Gallen , St. Gallen, Switzerland .
Christoph
C
Schwab
D000368:Aged; D000369:Aged, 80 and over; D001944:Breath Tests; D002318:Cardiovascular Diseases; D000431:Ethanol / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D011467:Prostate / Q000601:surgery*; D012307:Risk Factors; D012965:Sodium Chloride / Q000378:metabolism*; D007507:Therapeutic Irrigation / Q000379:methods*; D013932:Thulium; D014835:Volatilization
D000431:Ethanol; D012965:Sodium Chloride; D013932:Thulium
ethanol; intraoperative complications; laser therapy; prostate; therapeutic irrigation