Seroprevalence and risk factors of Coxiella burnetii infection among high-risk population in center of Iran, a neglected health problem.
In order to evaluate the prevalence of antibodies against phase I and II antigens of Coxiella Burnetii and to identify related risk factors among high-risk groups in the center of Iran, a serological survey was performed in Isfahan County. In a cross-sectional study, 401 sera were collected from slaughterhouse workers, butchers, farmers and veterinarians in spring 2015. Samples were tested for specific immunoglobulin G (IgG) antibodies against phase I and II of C. burnetii by indirect immunofluorescence assay. A checklist was fulfilled to document demographic information. Univariate analysis and multivariable binary logistic regression model were used to analyze data. IgG antibodies against phases I and II of C. burnetii were detected in 19% and 36.9% of participants, respectively. The overall seropositivity (IgG against phase I and/or II) was 43.1%. The present study shows a high seroprevalence of C. burnetii infection among high-risk population in center of Iran. It is suggested to carry out occupational health monitoring programs for individuals who may be exposed to C. burnetii.
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Zary
Z
Nokhodian
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Behrooz
B
Ataei
Isfahan Veterinary Office, Head of Public Health Supervision Section, Isfahan, Iran.
Abdolreza
A
Moradi
Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Majid
M
Yaran
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Shervin Gaffari
SG
Hoseini
Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: awat_feiz@hlth.mui.ac.ir.
Awat
A
Feizi
Acquired Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Roya
R
Sherkat
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000822:Animal Husbandry / Q000706:statistics & numerical data; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D016997:Coxiella burnetii; D003430:Cross-Sectional Studies; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D019649:Food Industry / Q000706:statistics & numerical data; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011778:Q Fever / Q000453:epidemiology*; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires; D018634:Veterinarians / Q000706:statistics & numerical data; D055815:Young Adult
D000907:Antibodies, Bacterial
C. burnetii; High-risk population; Iran; Seroprevalence