International consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: Executive summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology.
Food protein-induced enterocolitis (FPIES) is a non-IgE cell- mediated food allergy that can be severe and lead to shock. Despite the potential seriousness of reactions, awareness of FPIES is low; high-quality studies providing insight into the pathophysiology, diagnosis, and management are lacking; and clinical outcomes are poorly established. This consensus document is the result of work done by an international workgroup convened through the Adverse Reactions to Foods Committee of the American Academy of Allergy, Asthma & Immunology and the International FPIES Association advocacy group. These are the first international evidence-based guidelines to improve the diagnosis and management of patients with FPIES. Research on prevalence, pathophysiology, diagnostic markers, and future treatments is necessary to improve the care of patients with FPIES. These guidelines will be updated periodically as more evidence becomes available.
Anna
A
Nowak-Węgrzyn
Mirna
M
Chehade
Marion E
ME
Groetch
Jonathan M
JM
Spergel
Robert A
RA
Wood
Katrina
K
Allen
Dan
D
Atkins
Sami
S
Bahna
Ashis V
AV
Barad
Cecilia
C
Berin
Terri
T
Brown Whitehorn
A Wesley
AW
Burks
Jean-Christoph
JC
Caubet
Antonella
A
Cianferoni
Marisa
M
Conte
Carla
C
Davis
Alessandro
A
Fiocchi
Kate
K
Grimshaw
Ruchi
R
Gupta
Brittany
B
Hofmeister
J B
JB
Hwang
Yitzhak
Y
Katz
George N
GN
Konstantinou
Stephanie A
SA
Leonard
Jennifer
J
Lightdale
Sean
S
McGhee
Sami
S
Mehr
Stefano Miceli
SM
Sopo
Giovanno
G
Monti
Antonella
A
Muraro
Stacey Katherine
SK
Noel
Ichiro
I
Nomura
Sally
S
Noone
Hugh A
HA
Sampson
Fallon
F
Schultz
Scott H
SH
Sicherer
Cecilia C
CC
Thompson
Paul J
PJ
Turner
Carina
C
Venter
A Amity
AA
Westcott-Chavez
Matthew
M
Greenhawt
D004044:Dietary Proteins / Q000009:adverse effects* / Q000276:immunology; D004760:Enterocolitis / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D005512:Food Hypersensitivity / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans
D004044:Dietary Proteins
Food protein–induced enterocolitis syndrome; guidelines; non–IgE-mediated food allergy