Identification of diagnostic markers involved in the pathogenesis of gastric cancer through iTRAQ-based quantitative proteomics.
We provide detailed datasets from our analysis of proteins that are differentially expressed in gastric cancer tissues compared with adjacent normal gastric tissues, as identified by iTRAQ-based quantitative proteomics. Also included is a set of representative images of immunohistochemical staining of gastric cancer tissues showing four levels of expression of fatty acid binding protein (FABP1) and fatty acid synthase (FASN). The data presented in this paper support the research article "Quantitative proteomic analysis reveals that proteins required for fatty acid metabolism may serve as diagnostic markers for gastric cancer" (Jiang et al., 2017) [1]. We expect that the data will contribute to the identification of sensitive and specific biomarkers for early detection of gastric cancer.
Department of Biochemistry, School of Preclinical Medicine, North Sichuan Medical College, Nanchong, Sichuan Province 637100, PR China.
Zhen
Z
Jiang
College of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan Province 646000, PR China.
Hongchun
H
Shen
Department of Pathology, Affiliated Traditional Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, PR China.
Bo
B
Tang
Department of Biochemistry, School of Preclinical Medicine, North Sichuan Medical College, Nanchong, Sichuan Province 637100, PR China.
Hui
H
Chen
Research Center of Combine Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, PR China.
Qin
Q
Yu
Research Center of Combine Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, PR China.
Xingli
X
Ji
Research Center of Combine Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, PR China.
Li
L
Wang
ESI, electrospray ionization; FABP1, fatty acid binding protein; FASN, fatty acid synthase; GC, gastric cancer; LC, liquid chromatography; MS/MS, tandem mass spectrometry; iTRAQ, isobaric tag for relative and absolute quantitation