Antibacterial activities of Manuka and Honeydew honey-based membranes against bacteria that cause wound infections in animals.
In this study, membranes composed of honey (Manuka or Honeydew) and pectin were developed, and the ISO 22196 method was used to evaluate their antibacterial activities against multidrug-resistant bacteria (i.e., Staphylococcus pseudointermedius, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa) that cause wound infection in animals. The results demonstrated that both Manuka and Honeydew honey-based membranes had strong antibacterial activities against the strain of methicillin-resistant S. pseudointermedius tested. Specifically, membranes composed of Manuka honey were effective in inhibiting the growth of Gram-negative bacteria within 3 h, whereas those composed of Honeydew honey needed 24 h to neutralise bacterial growth. The antimicrobial activities of both membranes developed in this study suggest that they can be effectively used as wound dressing in veterinary clinical medicine.
Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
C
C
Tramuta
Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
P
P
Nebbia
Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
P
P
Robino
Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
G
G
Giusto
Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
M
M
Gandini
Piedmont Honey Producers Association, Torino, Italy.
S
S
Chiadò-Cutin
Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
E
E
Grego
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000472:pathogenicity; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D024901:Drug Resistance, Multiple, Bacterial; D006722:Honey; D008567:Membranes, Artificial; D008826:Microbial Sensitivity Tests; D014730:Veterinary Medicine / Q000379:methods; D014946:Wound Infection / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*
D000900:Anti-Bacterial Agents; D008567:Membranes, Artificial
Antibakterielle Aktivität; Membranen
aus Honigtauhonig; Wundinfektionen,
Hund; antibacterial activity; honey-based membranes,
multidrug-resistant bacteria; multiresistente Bakterien; wound infection