Unilateral occipital nerve stimulation for bilateral occipital neuralgia: a case report and literature review.
OBJECTIVE
The aim of this study is to present a case of successful relief of bilateral occipital neuralgia (ON) using unilateral occipital nerve stimulation (ONS) and to discuss the possible underlying mechanisms.


METHODS
We present the case of a 59-year-old female patient with severe bilateral ON treated with unilateral ONS. We systematically reviewed previous studies of ONS for ON, discussing the possible mechanisms of ONS in the relief of ON.


RESULTS
The patient reported complete pain relief after consistent unilateral ONS during the follow-up period. The underlying mechanisms may be linked to the relationship between pain and several brain regions, including the pons, midbrain, and periaqueductal gray.


CONCLUSIONS
ONS is an effective and safe option for treating ON. Future studies will be required to clarify the mechanisms by which unilateral occipital stimulation provided relief for bilateral neuralgia in this case.
Department of Neurosurgery, First Affiliated Hospital of PLA General Hospital, Beijing, People's Republic of China.
Aijun
A
Liu
Department of Neurosurgery, First Affiliated Hospital of PLA General Hospital, Beijing, People's Republic of China.
Yongcheng
Y
Jiao
Department of Neurosurgery, First Affiliated Hospital of PLA General Hospital, Beijing, People's Republic of China.
Huijun
H
Ji
Department of Neurosurgery, First Affiliated Hospital of PLA General Hospital, Beijing, People's Republic of China.
Zhiwen
Z
Zhang
neuromodulation; occipital neuralgia; peripheral nerve stimulation