Surgical Embolectomy for Acute Pulmonary Embolism: Systematic Review and Comprehensive Meta-Analyses.
Surgical pulmonary embolectomy (SPE) is a viable treatment approach for subsets of patients with acute pulmonary embolism. However, outcomes data are limited. We sought to characterize mortality and safety outcomes for this population. Studies reporting inhospital mortality for patients undergoing SPE for acute pulmonary embolism were included. In 56 eligible studies, we found 1,579 patients who underwent 1,590 SPE operations. The pooled inhospital all-cause mortality rate was 26.3% (95% confidence interval: 22.5% to 30.5%). Surgical site complications occurred in 7.0% of operations (95% confidence interval: 4.9% to 9.8%). More investigation is required to define the patient population that would benefit the most from SPE.
Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, and Cardiovascular Division, University of Minnesota, Minneapolis, Minnesota.
Rajat
R
Kalra
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama; Division of Cardiovascular Medicine and Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Navkaranbir S
NS
Bajaj
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama.
Pankaj
P
Arora
Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama.
Garima
G
Arora
Division of Cardiology, Emory University, Atlanta, Georgia.
William A
WA
Crosland
Division of Cardiac Surgery, Alfred Hospital and Monash University, Melbourne, Australia.
David C
DC
McGiffin
Division of Cardiology, Baptist Princeton, Birmingham, Alabama. Electronic address: musiahm@gmail.com.
Mustafa I
MI
Ahmed
D000208:Acute Disease; D017128:Embolectomy / Q000009:adverse effects* / Q000401:mortality; D017052:Hospital Mortality; D006801:Humans; D011655:Pulmonary Embolism / Q000401:mortality / Q000601:surgery*; D016896:Treatment Outcome