Does applying resolution recovery to normal databases confer an advantage over conventional 3D-stereotactic surface projection techniques?
We evaluated a novel normal database (NDB) generated using single photon emission computed tomography (SPECT) data obtained from healthy brains by using a SPECT/CT system, analyzed using a resolution recovery (RR) technique applied to the three-dimensional stereotactic surface projection (3D-SSP) technique. We used a three-dimensional ordered subset expectation maximization method (3D-OSEM) with applied scatter correction (SC), attenuation correction, and RR to reconstruct the data. We verified the accuracy of the novel NDB's values (Z, extent, and error scores), and compared the novel NDB to the 3D-SSP technique by using simulated misery perfusion-related patient data from a conventional NDB. In addition, Z, extent, and error scores at the precuneus, cuneus, and posterior cingulate were compared under different reconstruction conditions by using the patient data. In the simulation, Z scores decreased when using the novel NDB corrected using computed tomography-based attenuation correction (CTAC), SC, and RR. The extent scores of the posterior cingulate increased using the novel NDB, relative to the other NDBs. The error score with the novel NDB without RR decreased by 15% compared to that of the conventional NDB. Z scores generated from patient data decreased in the novel NDB with RR. The extent scores tended to decrease in the novel NDB with RR. The extent scores in the novel NDB with RR improved at the posterior cingulate, compared to the scores with the other NDBs. However, applying RR to the novel NDB conferred no advantage because the cut-off of the current Z score must be reconsidered when using the additive RR technique.
Biological Systems Sciences Program, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Shoubara, Japan. yata@med.shimane-u.ac.jp.|Department of Radiology, Shimane University Hospital, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan. yata@med.shimane-u.ac.jp.
Nobuhiro
http://orcid.org/0000-0001-9575-3969
N
Yada
Biological Systems Sciences Program, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Shoubara, Japan.
Hideo
H
Onishi
Department of Radiology, Shimane University Hospital, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Masahiro
M
Miyai
Department of Radiology, Shimane University Hospital, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Kentarou
K
Ozasa
Department of Radiology, Faculty of Medicine, Shimane University, Izumo, Japan.
Takashi
T
Katsube
Department of Neurology, Faculty of Medicine, Shimane University, Izumo, Japan.
Keiichi
K
Onoda
Department of Radiology, Shimane University Hospital, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Masuo
M
Haramoto
Department of Radiology, Shimane University Hospital, 89-1 Enya-Cho, Izumo, Shimane, 693-8501, Japan.
Yasushi
Y
Yamamoto
Department of Neurology, Faculty of Medicine, Shimane University, Izumo, Japan.
Shuhei
S
Yamaguchi
Department of Radiology, Faculty of Medicine, Shimane University, Izumo, Japan.
Hajime
H
Kitagaki
D000368:Aged; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery; D016208:Databases, Factual; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D055420:Perfusion Imaging; D000072098:Single Photon Emission Computed Tomography Computed Tomography; D013238:Stereotaxic Techniques
Brain perfusion; Normal database (NDB); Resolution recovery; Single photon emission tomography (SPECT); Three-dimensional stereotactic surface projection (3D-SSP)