Nanoscale size effect in in situ titanium based composites with cell viability and cytocompatibility studies.
Novel in situ Metal Matrix Nanocomposite (MMNC) materials based on titanium and boron, revealed their new properties in the nanoscale range. In situ nanocomposites, obtained through mechanical alloying and traditional powder metallurgy compaction and sintering, show obvious differences to their microstructural analogue. A unique microstructure connected with good mechanical properties reliant on the processing conditions favour the nanoscale range of results of the Ti-TiB in situ MMNC example. The data summarised in this work, support and extend the knowledge boundaries of the nanoscale size effect that influence not only the mechanical properties but also the studies on the cell viability and cytocompatibility. Prepared in the same bulk, in situ MMNC, based on titanium and boron, could be considered as a possible candidate for dental implants and other medical applications. The observed relations and research conclusions are transferable to the in situ MMNC material group. Aside from all the discussed relations, the increasing share of these composites in the ever-growing material markets, heavily depends on the attractiveness and a possible wider application of these composites as well as their operational simplicity presented in this work.
Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawla II 24, 61-138 Poznan, Poland. Electronic address: andrzej.miklaszewski@put.poznan.pl.
Andrzej
A
Miklaszewski
Division Mother's and Child's Health, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.
Mieczysława U
MU
Jurczyk
Department of Immunology, Chair of Clinical Immunology, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806 Poznan, Poland.
Mariusz
M
Kaczmarek
Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznan, Poland.
Anna
A
Paszel-Jaworska
Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznan, Poland.
Aleksandra
A
Romaniuk
Department of Clinical Chemistry and Molecular Diagnostics, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznan, Poland.
Natalia
N
Lipińska
Department of Immunobiochemistry, Chair of Biology and Environmental Sciences, Poznan University of Medical Sciences, Rokietnicka 8, 60-806 Poznan, Poland.
Jakub
J
Żurawski
Department of Cell Biology, Poznan University of Medical Sciences, Rokietnicka 5D, 60-806 Poznan, Poland.
Paulina
P
Urbaniak
Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawla II 24, 61-138 Poznan, Poland.
Mieczyslaw
M
Jurczyk
D001672:Biocompatible Materials / Q000494:pharmacology*; D002453:Cell Cycle / Q000187:drug effects; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D055119:Elastic Modulus; D005347:Fibroblasts / Q000166:cytology* / Q000187:drug effects; D006801:Humans; D008422:Materials Testing; D053758:Nanoparticles / Q000737:chemistry*; D010006:Osteoblasts / Q000166:cytology* / Q000187:drug effects; D010316:Particle Size; D016062:Porosity; D011208:Powders; D014025:Titanium / Q000494:pharmacology*; D014961:X-Ray Diffraction
D001672:Biocompatible Materials; D011208:Powders; D014025:Titanium
Cell viability and cytocompatibility; In situ TiB; Mechanical alloying; Nanoscale; Titanium metal matrix composite