Hepatoprotective effect of Syringae vulgaris flos ethanolic extracts in streptozotocin-induced diabetes in rats.
Taking account of increasing world population life expectancy, health services will face with a large number of elderly people with chronic age-related diseases. It has been established that chronic diseases are usually accompanied by oxidative stress induced by the overproduction of reactive oxygen species damaging cellular constituents, under conditions of weakening antioxidant defense systems. The balance between free radicals and antioxidant endogenous systems has a defining role in preventing the damage of macromolecules. In addition to the enzymatic (catalase, superoxide dismutase, glutathione peroxidase, glutathione reductase) and non-enzymatic (vitamins A, C, E) endogenous systems, a good source of natural antioxidants are medicinal herbs products or phytochemical compounds. The aim of this study is to evaluate the hepatoprotective effect of Syringae vulgaris flos ethanolic extracts in a rat model of streptozotocin-induced diabetes.
Department of Biochemistry, University of Medicine and Pharmacy of Craiova, Romania; camiparsot@yahoo.com.
Anca
A
Berbecaru-Iovan
Elena Camelia
EC
Stănciulescu
Ana Marina
AM
Andrei
Sorin
S
Berbecaru-Iovan
Cerasela Elena
CE
Gîrd
Cristiana Iulia
CI
Dumitrescu
Ileana Monica
IM
BaniŢă
Cătălina Gabriela
CG
Pisoschi
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy* / Q000378:metabolism; D000431:Ethanol / Q000737:chemistry; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D029592:Oleaceae / Q000737:chemistry*; D018384:Oxidative Stress / Q000187:drug effects; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D010936:Plant Extracts; D000431:Ethanol