CLINICAL AND MAGNETIC RESONANCE IMAGING FEATURES OF IDIOPATHIC OCULOMOTOR NEUROPATHY IN 14 DOGS.
Ophthalmoplegia/ophthalmoparesis (internal, external, or both) has been reported in dogs secondary to neoplasia affecting the oculomotor nerve and is usually given a poor prognosis. The purpose of this retrospective study was to describe the clinical findings, magnetic resonance imaging (MRI) findings, management, outcome, and follow-up in a group of canine cases with idiopathic oculomotor neuropathy. Inclusion criteria included cases with ophthalmoplegia/ophthalmoparesis (internal, external or both) as sole neuroophthalmologic signs, complete ophthalmic and neurologic examination, head MRI, and a minimum follow-up period of 1 year. Dogs with progressive neurological signs not related to oculomotor neuropathy were excluded. Fourteen cases met the inclusion criteria. All cases were unilaterally affected. Magnetic resonance imaging showed equivocal enlargement of the oculomotor nerve in three cases, mild enlargement in five, and marked enlargement in six. Contrast enhancement was present in 12 cases, being marked in six. When present, the contrast enhancement was focal in eight cases and diffuse in four. The median follow-up time was 25 months. External ophthalmoparesis improved in seven cases, five cases under no treatment and two under systemic corticosteroid therapy. The clinical signs in the other seven cases remained unchanged. Idiopathic oculomotor neuropathy should be included as a differential diagnosis in dogs presenting with unilateral ophthalmoplegia/ophthalmoparesis (internal, external, or both) with the absence of other neurologic and ophthalmic signs, and with the MRI findings restricted to the oculomotor nerve. Idiopathic oculomotor neuropathy has a good prognosis as the clinical signs do not deteriorate and they can improve without treatment.
Comparative Ophthalmology Unit, Animal Health Trust, Lanwades Park, Kentford CB8 7UU, UK.
Roser
R
Tetas Pont
Neurology/Neurosurgery Unit, Animal Health Trust, Lanwades Park, Kentford CB8 7UU, UK.
Courtenay
C
Freeman
Diagnostic Imaging Unit, Animal Health Trust, Lanwades Park, Kentford CB8 7UU, UK.
Ruth
R
Dennis
Comparative Ophthalmology Unit, Animal Health Trust, Lanwades Park, Kentford CB8 7UU, UK.
Claudia
C
Hartley
Neurology/Neurosurgery Unit, Animal Health Trust, Lanwades Park, Kentford CB8 7UU, UK.
Elsa
E
Beltran
D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D005260:Female; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D015840:Oculomotor Nerve Diseases / Q000000981:diagnostic imaging / Q000662:veterinary*; D009886:Ophthalmoplegia / Q000000981:diagnostic imaging / Q000662:veterinary*; D012189:Retrospective Studies
CNIII; MRI; canine; oculomotor nerve; ophthalmoplegia