Immunoglobulin G4-positive Sclerosing Idiopathic Orbital Inflammation: New Neuro-ophthalmological Presentations.
We report two rare cases of biopsy proven Immunoglobulin G4-related sclerosing orbital inflammation (IgG4SOI). The first case had intracranial involvement which, to our knowledge, is the first IgG4SOI case with serum cerebrospinal fluid abnormalities and the second case had an unusual presentation of a compressive optic neuropathy and systemic lymphadenopathy.
Department of Ophthalmology, The Methodist Hospital Houston, TX USA.
Nagham
N
Al-Zubidi
Department of Ophthalmology, Osaka Medical College Osaka Japan.
Hidehiro
H
Oku
The Department of Pathology and Laboratory Medicine, The Methodist Hospital.
Elizabeth
E
Verner-Cole
The Department of Pathology and Laboratory Medicine, The Methodist Hospital; Department of Pathology and Laboratory Medicine and Ophthalmology, Weill Cornell Medical College, Retinoblastoma Center of Houston; Department of Ophthalmology, Baylor College of Medicine; Department of Pathology and Laboratory Medicine, University of Texas MD Anderson Cancer CenterHouston, TXUSA.
Patricia
P
Chévez-Barrios
Department of Ophthalmology, Osaka Medical College Osaka Japan.
Masahiro
M
Tonari
Department of Ophthalmology, Osaka Medical College Osaka Japan.
Takuji
T
Kurimoto
Department of Pathology, Osaka Medical College Osaka Japan.
Motomu
M
Tsuji
Department of Ophthalmology, Osaka Medical College Osaka Japan.
Tsunehiko
T
Ikeda
Department of Ophthalmology, The Methodist HospitalHouston, TXUSA; Department of Ophthalmology, Baylor College of Medicine; Departments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medical CollegeHoustonTX; Department of Ophthalmology, The University of Iowa Hospitals and ClinicsIowa City, IA; Department of Ophthalmology, The University of Texas Medical BranchGalveston, TXUSA.
Andrew G
AG
Lee
Compressive optic neuropathy; IgG4; immunoglobulin G4-positive sclerosing idiopathic orbital inflammation; immunoglobulin G4-positive with intracranial involvement; sclerosing idiopathic orbital inflammation; systemic lymphadenopathy