Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes.
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Zhifen
Z
Chen
Institute for Molecular Cell Biology, Medical Faculty, University Homburg/Saar, Universität des Saarlandes, Homburg/Saar 66421, Germany.
Wenying
W
Xian
Department of Anatomy and Embryology, Leiden University Medical Center, Leiden 2333, The Netherlands.
Milena
M
Bellin
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Tatjana
T
Dorn
Institute for Molecular Cell Biology, Medical Faculty, University Homburg/Saar, Universität des Saarlandes, Homburg/Saar 66421, Germany.
Qinghai
Q
Tian
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Alexander
A
Goedel
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Lisa
L
Dreizehnter
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Christine M
CM
Schneider
Department of Anatomy and Embryology, Leiden University Medical Center, Leiden 2333, The Netherlands.
Dorien
D
Ward-van Oostwaard
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Judy King Man
JK
Ng
Rabea
R
Hinkel
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Luna Simona
LS
Pane
Department of Anatomy and Embryology, Leiden University Medical Center, Leiden 2333, The Netherlands.
Christine L
CL
Mummery
Institute for Molecular Cell Biology, Medical Faculty, University Homburg/Saar, Universität des Saarlandes, Homburg/Saar 66421, Germany.
Peter
P
Lipp
Alessandra
A
Moretti
Karl-Ludwig
KL
Laugwitz
I. Department of Medicine (Cardiology), Klinikum rechts der Isar, Technische Universität München, Munich 81675, Germany.
Daniel
D
Sinnecker
D000200:Action Potentials / Q000502:physiology; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D016022:Case-Control Studies; D020117:Cisapride / Q000494:pharmacology; D004341:Drug Evaluation / Q000379:methods; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000502:physiology*; D000077550:Ivabradine / Q000494:pharmacology; D008133:Long QT Syndrome / Q000503:physiopathology; D008164:Luminescent Proteins / Q000378:metabolism; D008955:Models, Cardiovascular; D032383:Myocytes, Cardiac / Q000378:metabolism / Q000502:physiology*; D026902:Potassium Channel Blockers / Q000494:pharmacology; D056969:Voltage-Sensitive Dye Imaging / Q000379:methods*
D000889:Anti-Arrhythmia Agents; D008164:Luminescent Proteins; D026902:Potassium Channel Blockers; D000077550:Ivabradine; D020117:Cisapride