MRI and clinical manifestations of delayed encephalopathy after carbon monoxide poisoning.
To explore the relationship between the clinical manifestations and functional magnetic resonance images of delayed encephalopathy after carbon monoxide intoxication. Six patients received the MRI were diagnosed with delayed encephalopathy after carbon monoxide (CO) poisoning. Clinical manifestations were observed in each patient. MRI revealed multiple lesions. The majority of the lesions were located in the globus pallidus, sub cortical white matter, and basal ganglia. The cognitive injury, akinetic mutism, fecal and uroclepsia, forced crying, forced laughing and extra pyramidal syndromes such as chorea and parkinsonism were manifested in clinic. Cognitive impairment improved greatly while involuntary movements only improved slightly after several months. Meanwhile brain MRI suggested remarkable improvement. Neuroimaging directly correlated with the clinical manifestations.
Department of Neurology, The Second People's Hospital of Zhengzhou, Zhengzhou, Henan, China.
Xiahong
X
Wang
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Zhenyu
Z
Li
Department of Neurology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA.
Jacqueline
J
Berglass
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Wenlong
W
He
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Jianmin
J
Zhao
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Min
M
Zhang
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Chongyang
C
Gao
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Caixia
C
Zhang
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Huimin
H
Zhang
Department of Neurology, Xinxiang Central hospital, Xinxiang, Henan, China.
Xuewei
X
Yi
D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging*; D001927:Brain Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D002249:Carbon Monoxide Poisoning / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D002681:China; D003071:Cognition; D003072:Cognition Disorders / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D004409:Dyskinesia, Drug-Induced / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D005260:Female; D059907:Functional Neuroimaging / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D020127:Recovery of Function; D012189:Retrospective Studies; D013997:Time Factors