Cultivated limbal epithelial transplantation and penetrating keratoplasty postchemical injury: a 14-year follow-up.
An 11-year-old girl presented to our tertiary eye care centre with a 9-month-old history of lime injury in the left eye in 1999 with vision of counting fingers close to the face. She initially underwent superficial keratectomy with amniotic membrane graft in 1999. Subsequently, cultivated limbal epithelial transplantation was performed in 2001 which improved her vision to 20/400. Following development of pannus and symblepharon in the left eye, she underwent pannus resection and conjunctival limbal autograft in 2002 and, a month later, optical penetrating keratoplasty (PK) following which her vision improved to 20/125. She was under regular follow-up, underwent exotropia correction and subsequent levator palpebrae superioris resection for ptosis and was maintaining good vision. On her last follow-up 14 years after PK in 2016, her vision in the left eye was 20/40 with lipid keratopathy and her right eye showed no signs of focal limbal stem cell deficiency.
L V Prasad Eye Institute, Tej Kohli Cornea Institute, Hyderabad, Telangana, India.
Ritu
R
Shah
L V Prasad Eye Institute, Tej Kohli Cornea Institute, Hyderabad, Telangana, India.
Charuta
C
Puranik
Ophthalmic Biophysics Laboratory, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Ashik
http://orcid.org/0000-0001-5520-4930
A
Mohamed
L V Prasad Eye Institute, Centre for Ocular Regeneration, Hyderabad, Telangana, India.
Virender S
http://orcid.org/0000-0002-8229-4158
VS
Sangwan
D000328:Adult; D017610:Calcium Compounds; D003316:Corneal Diseases / Q000601:surgery*; D019573:Epithelium, Corneal / Q000637:transplantation*; D005126:Eye Burns / Q000139:chemically induced*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015948:Keratoplasty, Penetrating; D016850:Limbus Corneae / Q000166:cytology / Q000601:surgery; D010087:Oxides; D033581:Stem Cell Transplantation; D016896:Treatment Outcome; D014792:Visual Acuity
D017610:Calcium Compounds; D010087:Oxides; C016538:lime