Acceptorless Dehydrogenation of N-Heterocycles by Merging Visible-Light Photoredox Catalysis and Cobalt Catalysis.
Herein, the first acceptorless dehydrogenation of tetrahydroquinolines (THQs), indolines, and other related N-heterocycles, by merging visible-light photoredox catalysis and cobalt catalysis at ambient temperature, is described. The potential applications to organic transformations and hydrogen-storage materials are demonstrated. Primary mechanistic investigations indicate that the catalytic cycle occurs predominantly by an oxidative quenching pathway.
Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.|Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China.
Ke-Han
KH
He
Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Fang-Fang
FF
Tan
Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Chao-Zheng
CZ
Zhou
Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China.
Gui-Jiang
GJ
Zhou
Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China.
Xiao-Long
XL
Yang
Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Yang
Y
Li
cobalt; dehydrogenation; heterocycles; photochemistry; reaction mechanisms