[Sertoli-Leydig cell tumor of the ovary: case study of a 22-year old woman].
Sertoli-Leydig cell tumors are rare secreting mesenchymal and sex cord-stromal tumors. However, they constitute one type of tumor most often responsible for virilization syndrome. A definite diagnosis is provided by histological examination following surgical excision of the tumor. It has no characterizing features on ultrasonography, in spite of the strong clinical presumption. Like many neoplasias, prognosis is related to the degree of cellular differentiation and to the presence of heterologous elements. The aim of our study was to report the case of a 22-year old woman suffering from a real virilization syndrome secondary to non-epithelial Sertoli-Leydig cell tumor of the ovary. Poorly differentiated Sertoli-Leydig tumors have high malignant potential. Treatment is surgical; taxane-platinum combination chemotherapy is an interesting adjuvant. Prognosis after surgical resection is related to the risk of relapses.
Centre Service de Gynécologie-Obstétrique, Centre Hospitalier National de Pikine Sis Camp de Thiaroye, Dakar, Sénégal.
Diallo
D
Moussa
Centre Service de Gynécologie-Obstétrique, Centre Hospitalier National de Pikine Sis Camp de Thiaroye, Dakar, Sénégal.
Diouf Abdoul
DA
Aziz
Clinique Gynécologique et Obstétricale de l'Hôpital Aristide Le Dantec, Dakar, Sénégal.
Diallo Astou Coly
DA
Niassy
Centre Service de Gynécologie-Obstétrique, Centre Hospitalier National de Pikine Sis Camp de Thiaroye, Dakar, Sénégal.
Koulimaya Cyre
KC
Espérence
Centre Service de Gynécologie-Obstétrique, Centre Hospitalier National de Pikine Sis Camp de Thiaroye, Dakar, Sénégal.
Niang
N
Youssou
Clinique Gynécologique et Obstétricale de l'Hôpital Aristide Le Dantec, Dakar, Sénégal.
Moreau Jean
MJ
Charles
Centre Service de Gynécologie-Obstétrique, Centre Hospitalier National de Pikine Sis Camp de Thiaroye, Dakar, Sénégal.
Diouf
D
Alassane
D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D018310:Sertoli-Leydig Cell Tumor / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D014770:Virilism / Q000209:etiology*; D055815:Young Adult
Sertoli-leydig; Tumour; ovary; virilisation