Interplay between miRNAs and human diseases.
MicroRNAs (miRNAs) are endogenous, non-coding RNAs, which have evoked a great deal of interest due to their importance in many aspects of homeostasis and diseases. MicroRNAs are stable and are essential components of gene regulatory networks. They play a crucial role in healthy individuals and their dysregulations have also been implicated in a wide range of diseases, including diabetes, cardiovascular disease, kidney disease, and cancer. This review summarized the current understanding of interactions between miRNAs and different diseases and their role in disease diagnosis and therapy.
Department of Biotechnology, Assam University, Silchar, Assam, India.
Prosenjit
P
Paul
Department of Biotechnology, Assam University, Silchar, Assam, India.
Anindya
A
Chakraborty
Department of Biotechnology, Assam University, Silchar, Assam, India.
Debasree
D
Sarkar
Department of Biotechnology, Assam University, Silchar, Assam, India.
Malobika
M
Langthasa
Department of Biotechnology, Assam University, Silchar, Assam, India.
Musfhia
M
Rahman
Department of Biotechnology, Assam University, Silchar, Assam, India.
Minakshi
M
Bari
Department of Biotechnology, Assam University, Silchar, Assam, India.
Rk Sanamacha
RS
Singha
Department of Biotechnology, Assam University, Silchar, Assam, India.
Arup Kumar
AK
Malakar
Department of Biotechnology, Assam University, Silchar, Assam, India.
Supriyo
S
Chakraborty
D050197:Atherosclerosis / Q000235:genetics*; D009202:Cardiomyopathies / Q000235:genetics*; D003920:Diabetes Mellitus / Q000235:genetics*; D053263:Gene Regulatory Networks; D006801:Humans; D007674:Kidney Diseases / Q000235:genetics*; D035683:MicroRNAs / Q000235:genetics*; D009369:Neoplasms / Q000235:genetics*
D035683:MicroRNAs
cancer; homeostasis; insulin; kidney disease; miRNA