Big-Data-Driven Stem Cell Science and Tissue Engineering: Vision and Unique Opportunities.
Achieving the promises of stem cell science to generate precise disease models and designer cell samples for personalized therapeutics will require harnessing pheno-genotypic cell-level data quantitatively and predictively in the lab and clinic. Those requirements could be met by developing a Big-Data-driven stem cell science strategy and community.
Computational Biology Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6 Avenue du Swing, Belvaux 4367, Luxembourg. Electronic address: antonio.delsol@uni.lu.
Antonio
A
Del Sol
Institute of Immunology, Universitätsmedizin Rostock, University of Rostock, 18051 Rostock, Germany.
Hans J
HJ
Thiesen
Laboratory for Neural Stem Cells and Functional Neurogenetics, Departments of Neurology and Neuroscience, and Molecular Biology and Cancer Genetic Program, The James Comprehensive Cancer Hospital, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Jaime
J
Imitola
Pharmacology Department and Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK. Electronic address: rafael.carazosalas@bristol.ac.uk.
Rafael E
RE
Carazo Salas
D000818:Animals; D019295:Computational Biology; D006801:Humans; D010641:Phenotype; D012586:Science; D013223:Statistics as Topic; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering