Cognitive behavioural therapy on improving the depression symptoms in patients with diabetes: a meta-analysis of randomized control trials.
This meta-analysis was performed to evaluate the effect of cognitive behavioural therapy (CBT) in improving the depression symptoms of patients with diabetes. Literature search was conducted in PubMed and Embase up to October 2016 without the initial date. The pooled SMD (standard mean difference) and its 95% confidence interval (CI) were calculated by Revman 5.3. Subgroup analyses were performed by type of diabetes and evaluation criteria of depression. A total of five randomized control trials involving 834 patients with diabetes mellitus (including 417 patients in CBT group and 417 patients in control group) were included in this meta-analysis. The pooled estimates indicated significant improvement of depression by CBT compared with routine approaches in overall outcomes (SMD =-0.33, 95% CI =-0.46 to -0.21,P<0.00001), post-intervention outcomes (SMD =-0.43, 95% CI =-0.73 to -0.12,P=0.006) and outcomes after 12 months intervention (SMD =-0.38, 95% CI = -0.54 to -0.23,P<0.0001). Subgroup analyses showed that the results were not influenced by the type of diabetes. However, the effect of CBT on improving the depression symptoms disappeared when only using CES-D (Centre for Epidemiological Studies scale for Depression) to evaluate depression.
Key Laboratory of Hormones and Development (Ministry of Health), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300070, China.
Zhi-da
ZD
Wang
School of Nursing, Tianjin Medical University, Tianjin 300070, China.
Yu-Fei
YF
Xia
School of Nursing, Tianjin Medical University, Tianjin 300070, China yuezhao35@hotmail.com xfx22081@vip.163.com.
Yue
Y
Zhao
Key Laboratory of Hormones and Development (Ministry of Health), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300070, China yuezhao35@hotmail.com xfx22081@vip.163.com.
Li-Ming
LM
Chen
D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003863:Depression / Q000503:physiopathology* / Q000628:therapy*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods / Q000706:statistics & numerical data; D016032:Randomized Controlled Trials as Topic
cognitive behavioral therapy; depression; diabetes; meta analysis