Potential probiotic-associated traits revealed from completed high quality genome sequence ofLactobacillus fermentum3872.
The article provides an overview of the genomic features ofLactobacillus fermentumstrain 3872. The genomic sequence reported here is one of threeL. fermentumgenome sequences completed to date. Comparative genomic analysis allowed the identification of genes that may be contributing to enhanced probiotic properties of this strain. In particular, the genes encoding putative mucus binding proteins, collagen-binding proteins, class III bacteriocin, as well as exopolysaccharide and prophage-related genes were identified. Genes related to bacterial aggregation and survival under harsh conditions in the gastrointestinal tract, along with the genes required for vitamin production were also found.
School of Life Sciences, Pharmacy and Chemistry, SEC Faculty, Kingston University, Penryn Road, Kingston upon Thames, KT1 2EE UK.
Burhan
B
Lehri
School of Life Sciences, Pharmacy and Chemistry, SEC Faculty, Kingston University, Penryn Road, Kingston upon Thames, KT1 2EE UK.
Alan M
AM
Seddon
School of Life Sciences, Pharmacy and Chemistry, SEC Faculty, Kingston University, Penryn Road, Kingston upon Thames, KT1 2EE UK.
Andrey V
0000-0003-3124-019X
AV
Karlyshev
Bacteriocin; Collagen binding protein; Genome sequencing; Lactobacillus fermentum; Mucus binding protein; Probiotics; Prophage