Warfarin related acute kidney injury: A case report.
Warfarin is an oral anticoagulant used extensively in clinical practice; However, its side-effect of causing renal damage has been recently detected. The mechanism leading to renal damage is glomerular hemorrhage and red blood cell tubular casts prothrombin time. Recently, it was found that warfarin causes renal damage in patients with chronic kidney disease and is also associated with progression of renal disease. Warfarin causing acute kidney injury in patients with normal renal function is a rare manifestation. It is important to be aware of this condition as its innocuous presence can lead to chronic kidney disease if not corrected in time. Further studies have also found that novel oral anticoagulants such as dabigatran also cause a similar syndrome and hence a new term called anticoagulant-related nephropathy is now in vogue.
Department of Medicine, Armed Forces Medical College and Command Hospital, Pune, Maharashtra, India.
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Mendonca
Department of Pathology and Laboratory Science and Armed Forces Medical College and Command Hospital, Pune, Maharashtra, India.
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Gupta
Department of Medicine, Armed Forces Medical College and Command Hospital, Pune, Maharashtra, India.
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Valsan
Department of Medicine, Armed Forces Medical College and Command Hospital, Pune, Maharashtra, India.
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Tewari
Acute kidney injury; anticoagulant-related nephropathy; warfarin; warfarin-related nephropathy