Leukocytosis due to markedly elevated granulocyte-colony stimulating factor levels in a patient with endometrial cancer: Case report and literature review.
•Granulocyte-colony stimulating factor (GCSF) secretion by gynecologic tumors is rare.•Elevations in serum GCSF can be seen in the absence of tumor GSCF secretion.•Extreme leukocytosis is associated with autocrine tumor growth and poor prognosis.
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina, United States.
Leslie H
LH
Clark
Department of Medicine, Division of Hematology-Oncology, University of North Carolina School of Medicine, United States.
Stephan
S
Moll
Department of Medicine, Division of Hematology-Oncology, University of North Carolina School of Medicine, United States.
Damon
D
Houghton
Department of Pathology, University of North Carolina School of Medicine, United States.
Siohban
S
O'Connor
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina, United States.
John T
JT
Soper
Endometrial cancer; GCSF; Granulocyte colony stimulating factor; Leukocytosis; Prognosis