Synthesis of Lactones and Other Heterocycles.
Chemical fixation of CO2into value-added chemicals represents a promising field in view of sustainable development and green synthesis. In this aspect, the construction of heterocyclic compounds from CO2and readily available starting materials is particularly appealing in both organic and pharmaceutical fields since CO2can be regarded as carbon and oxygen resource with advantages of abundance, renewability, non-toxicity, and non-flammability. In this chapter, we have summarized elegant protocols with elaborately designed substrates for the direct incorporation of entire CO2molecule or "CO" or "C" fragments into lactones and other heterocycles such as oxazolidinones, cyclic carbonates, quinazoline-2,4(1H,3H)-diones, etc., through the formation of carbon-carbon, carbon-nitrogen and/or carbon-oxygen bonds promoted by homogeneous catalysts.
State Key Laboratory and Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin, 300071, People's Republic of China.
Xi
X
Liu
State Key Laboratory and Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin, 300071, People's Republic of China. heln@nankai.edu.cn.
Liang-Nian
http://orcid.org/0000-0002-6067-5937
LN
He
D002245:Carbon Dioxide / Q000737:chemistry; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry
D006571:Heterocyclic Compounds; D007783:Lactones; D002245:Carbon Dioxide; D009584:Nitrogen; D010100:Oxygen
Carbon dioxide; Catalysis; Heterocycle; Lactone; Sustainable chemistry; Synthetic methods