Microbial shifts in the porcine distal gut in response to diets supplemented with Enterococcus Faecalis as alternatives to antibiotics.
Gut microbiota plays an important role in host health and nutrient digestion of animals. Probiotics have become one of effective alternatives to antibiotics enhancing animal health and performance through modulating gut microbiota. Previously, our research demonstrated that dietary Enterococcus Faecalis UC-100 substituting antibiotics enhanced growth and health of weaned pigs. To investigate the alterations of microbiota in the distal gut of pigs fed E. faecalis UC-100 substituting antibiotics, this study assessed fecal microbiota in pigs from different dietary treatments: the basal diet group, the E. faecalis group, and the antibiotic group on d 0, 14, and 28 of feeding through 16 S rRNA sequencing. Twenty-one phyla and 137 genera were shared by all pigs, whereas 12 genera were uniquely identified in the E. faecalis group on d 14 and 28. Bacterial abundance and diversity in the E. faecalis group, bacterial diversity in the antibiotic group, especially abundances of Fibrobacteres phylum and 12 genera in the E. faecalis group and antibiotics group were lower than that in the basal diet group on d 28. These results showed that microbial shifts in the porcine gut in response to diets containing E. faecalis were similar to the response to which containing antibiotics.
Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, China.|Huaian Academy of Nanjing Agricultural University, Huaian, 223005, China.
Pinghua
P
Li
Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, China.|Huaian Academy of Nanjing Agricultural University, Huaian, 223005, China.
Qing
Q
Niu
Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, China.|Huaian Academy of Nanjing Agricultural University, Huaian, 223005, China.
Qingtian
Q
Wei
Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, China.|Huaian Academy of Nanjing Agricultural University, Huaian, 223005, China.
Yeqiu
Y
Zhang
Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, China.|Huaian Academy of Nanjing Agricultural University, Huaian, 223005, China.
Xiang
X
Ma
Department of Animal Science, North Carolina State University, Raleigh, North Carolina, 27695, United States of America.
Sung Woo
SW
Kim
Changxing Ecoagriculture Co. Limited, Yixing, 214246, China.
Mingxin
M
Lin
Institute of Swine Science, Nanjing Agricultural University, Nanjing, 210095, China.|Huaian Academy of Nanjing Agricultural University, Huaian, 223005, China.
Ruihua
R
Huang
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001483:Base Sequence; D044822:Biodiversity; D004032:Diet; D019587:Dietary Supplements; D013293:Enterococcus faecalis / Q000502:physiology*; D000069196:Gastrointestinal Microbiome / Q000187:drug effects; D025341:Principal Component Analysis; D034421:Sus scrofa / Q000382:microbiology*
D000900:Anti-Bacterial Agents