Bacterial cell cycle classification. Application to DNA synthesis and DNA content at any cell age.
A proposal is presented for classifying bacterial cell cycles into twelve discrete groups. This classification translates the three temporal parameters that define a cell cycle into numbers that facilitate an algorithmic approach to analyse the replication state of a single bacterium and of a bacterial population during steady-state of exponential growth. The classification and its implementation offer easy ways to obtain the rate of DNA synthesis and the amount of DNA per cell at any age in batch cultures.
Dpto. Genética, Universidad de Extremadura, E06071 Badajoz, Spain. Electronic address: a.jimenezsanchez@gmail.com.
Alfonso
A
Jiménez-Sánchez
D000465:Algorithms; D002453:Cell Cycle / Q000235:genetics / Q000502:physiology*; D002455:Cell Division / Q000235:genetics / Q000502:physiology; D002876:Chromosomes, Bacterial / Q000235:genetics; D004261:DNA Replication / Q000235:genetics / Q000502:physiology; D004269:DNA, Bacterial / Q000145:classification / Q000235:genetics; D004926:Escherichia coli / Q000166:cytology* / Q000235:genetics; D007700:Kinetics; D008954:Models, Biological; D013997:Time Factors
D004269:DNA, Bacterial
Cell cycle parameters; DNA per cell; Rate of growth; Replication rate; rcd