[Infective endocarditis by Abiotrophia defectiva diagnosed by mass spectrometry (MALDI-TOF MS) in Argentina].
We report the case of a 63-year-old woman with congestive heart failure due to a bicuspid aortic valve and severe aortic stenosis. The patient had a febrile syndrome with positive blood cultures for Abiotrophia defectiva, Transesophageal echocardiogram revealed the presence of paravalvular abscess, which was treated by a successful valve replacement. The patient received appropriate antibiotic therapy with intravenous vancomycin, leading to a successful response. The use of MALDI-TOF MS as a rapid and specific method for the microbiological diagnosis is discussed in the following report.
Servicio de Infectología, Hospital Privado Universitario de Córdoba, Argentina.
Flavo
F
Lipari
Servicio de Cardiología, Hospital Privado Universitario de Córdoba, Argentina.
Matías
M
Martínez
Servicio de Microbiología, Hospital Privado Universitario de Córdoba, Argentina.
Daniela
D
Hernández
Servicio de Anatomía Patológica, Hospital Privado Universitario de Córdoba, Argentina.
María
M
Laborie
Servicio de Infectología, Hospital Privado Universitario de Córdoba, Argentina.
Juan P
JP
Caeiro
D058835:Abiotrophia / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014640:Vancomycin