Four cases of Morbihan disease successfully treated with doxycycline.
Morbihan disease (MD) is rosacea-like disease characterized by persistent lymphedema on the upper half of the face. Currently, there is no established standard treatment for MD. Recently, MD has been reported to be associated with the infiltration of mast cells. The aim of this study was to investigate the association of treatment response and mast cell infiltration in MD. We report four cases of MD that were successfully treated with long-term oral doxycycline therapy.
Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, Japan.
Ayaka
A
Okubo
Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, Japan.
Kazuhiro
K
Takahashi
Department of Dermatology, Kitakami Saiseikai Hospital, Kitakami, Japan.
Toshihide
T
Akasaka
Department of Dermatology, School of Medicine, Iwate Medical University, Morioka, Japan.
Hiroo
H
Amano
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004318:Doxycycline / Q000627:therapeutic use*; D005148:Facial Dermatoses / Q000188:drug therapy*; D006801:Humans; D008209:Lymphedema / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D000900:Anti-Bacterial Agents; D004318:Doxycycline
Morbihan disease; doxycycline; eyelid edema; minocycline; rosacea