Synovial sarcoma of the hard palate: The third case in the medical literature.
Synovial sarcoma is a high-grade soft tissue sarcoma that rarely arises in the head and neck region. It affects the parapharyngeal space and the hypopharynx most commonly and it has different presentations based on the affected site. In extremely rare occasions, it involves the hard palate such as in our case where a 24-year-old female patient presented with a mass lesion involving the left hard palate, which was identified clinically and by imaging studies. The histopathological assessment confirmed that it was a monophasic synovial sarcoma which was also confirmed with further molecular studies. The patient underwent surgical excision and postoperative radiotherapy. Her close follow up over a 6-year period that followed her curative treatment has demonstrated no evidence of disease recurrence or distant metastasis. Surgical excision is the mainstay of treatment for synovial sarcoma and adjuvant radiotherapy is advised. Long-term follow up is recommended because of the remote possibility of late recurrence of the tumor.
Saudi Otolaryngology Program, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. Electronic address: aodoubi@gmail.com.
Aseel
A
Doubi
Department of Otolaryngology/Head & Neck Surgery/Communication Sciences, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Motaz
M
Doubi
Department of Otolaryngology/Head & Neck Surgery/Communication Sciences, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Nabil
N
Alzaher
Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Asma
A
Tulbah
D000328:Adult; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D021362:Palate, Hard / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D013584:Sarcoma, Synovial / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology / Q000628:therapy
Hard palate sarcoma of the head and neck; Synovial sarcoma; Synovial sarcoma of the hard palate