Antifungal Activity of Two Root Canal Sealers against Different Strains ofCandida.
BACKGROUND
Microorganisms and microbial products are the main etiologic factors in pulp and periapical diseases. The present study aimed to compare the antifungal activity of two different sealers, AH-26 and MTA Fillapex against three strains ofCandida,24, 48, 72 h and 7 days after mixing.


METHODS
The microorganisms used in this study wereCandidia albicans (ATCC 10231), Candidia glabrata(ATCC 90030) andCandidia krusei(DSM 70079). This test was based on growth of microorganisms and turbidity measurement technique using a spectrophotometer. The direct contact test was conducted by direct and indirect methods. Multiple comparisons were carried out using analysis of variances (ANOVA) with repeated measures followed by Tukey's tests.


RESULTS
The antifungal activity of both sealers was similar in the indirect method. The antifungal activity of both sealers in the direct method was similar againstCandida albicansand higher for AH-26 sealer againstCandida kruseiandCandida glabrata.


CONCLUSIONS
The total antifungal effect of MTA Fillapex sealer was significantly less than AH-26 sealer in direct method. The antifungal effect of both sealers was similar in indirect method.
Department of Endodontics, Dental School, Tabriz University of Medical Sciences, Tabriz, Iran.
Farnaz
F
Jafari
Department of Orthodontics, Dental School, Ilam University of Medical Sciences, Ilam, Iran.
Sanaz
S
Jafari
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hossein
H
Samadi Kafil
Dentist, Dental School, Tabriz University of Medical Sciences, Tabriz, Iran.
Tahereh
T
Momeni
Dentist, Dental School, Tabriz University of Medical Sciences, Tabriz, Iran.
Helen
H
Jamloo
Antifungal; Antimicrobial; Candida; Endodontic Sealers