Some Important Dietary Polyphenolic Compounds: An Anti-inflammatory and Immunoregulatory Perspective.
Inflammation plays an important role in maintaining the body's homeostasis. It repairs the damaged tissues of the body resulting from injury or infection. In addition, a diverse array of diseases like hepatitis, arthritis and colitis has been reported and described to be associated with inflammatory processes. Some autoimmune diseases like inflammatory bowel disease (IBD) emerge by the influence of numerous genes in complex environmental situations belong to inflammation. The currently available processes for curing inflammation and related disorders facilitate the use of non steroidal antiinflammatory drugs (NSAIDs). Moreover, intolerable side effects are also associated with the consumption of these medications. It is well known that phenolic compounds, largely present in vegetables and fruits, serve as an integral part of normal human diet besides having great medicinal value. These are considered to reflect a variety of anti-inflammatory properties, and can be used as an alternate natural source for the prevention of chronic inflammatory disorders. This mini-review summarized the antiinflammatory benefits of plants derived very prominent dietary polyphenolic compounds particularly, Oleocanthal, Curcumin, Resveratrol and Quercetin.
Department of Chemistry, Maharishi Markandeshwar University, Mullana, Ambala-133207, Haryana, India.
Mayank
M
Kinger
Department of Chemistry, Maharishi Markandeshwar University, Mullana, Ambala-133207, Haryana, India.
Sushil
S
Kumar
Department of Chemistry, Maharishi Markandeshwar University, Mullana, Ambala-133207, Haryana, India.
Vinod
V
Kumar
D000447:Aldehydes / Q000737:chemistry / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000473:pathology / Q000517:prevention & control*; D003474:Curcumin / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use; D000081004:Cyclopentane Monoterpenes; D004032:Diet; D006801:Humans; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology / Q000378:metabolism; D010636:Phenols / Q000737:chemistry / Q000627:therapeutic use; D059808:Polyphenols / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D011794:Quercetin / Q000737:chemistry / Q000627:therapeutic use; D000077185:Resveratrol; D013267:Stilbenes / Q000737:chemistry / Q000627:therapeutic use
D000447:Aldehydes; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000081004:Cyclopentane Monoterpenes; D010636:Phenols; D059808:Polyphenols; D013267:Stilbenes; D011794:Quercetin; C503534:oleocanthal; D003474:Curcumin; D000077185:Resveratrol
Curcumin; inflammation; oleocanthal; polyphenol; quercetin; resveratrol.