Surgical pathology, management and outcome in the vulvar melanoma associated with abdominal mass - a case report.
Vulvar malignant melanomas are extremely rare neoplasms, representing less than 3% of all cancers in women, 9% of all external genital tract malignancies and 9% of all primary vulvar malignancies. We present the case of a 60-year-old Caucasian patient, who has been admitted in the Clinic of Obstetrics and Gynecology with polymorphic, vulvar local, pelvic-abdominal, genitourinary and general symptoms, being diagnosed with nodular and superficial spreading vulvar melanoma and multiple voluminous uterine leiomyoma with various degenerations. Our study presents the approach of this case in terms of surgical pathology, management, prognosis and outcome. Surgical treatment is the central element of therapeutic management. Vulva melanomas are in general a relatively unpredictable unfavorable prognosis. The sizes of the tumor, the thickness and micro-staging are essential factors for prognosis.
Department of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy, "Nicolae Malaxa" Clinical Hospital, Bucharest, Romania; claudiamehedintu@yahoo.com.
Costin
C
Berceanu
Florinel
F
Pop
Claudia
C
MehedinŢu
Monica Mihaela
MM
Cîrstoiu
Răzvan
R
Ciortea
Sabina
S
Berceanu
Ioana Andreea
IA
Gheonea
Elvira
E
Brătilă
D000005:Abdomen / Q000473:pathology*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D014846:Vulvar Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*