Randomized Double-Blind Controlled Trial of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease.
1 Barts Health NHS Trust London, United Kingdom.|8 * University College London London, United Kingdom.
Alex J
AJ
Mackay
2 University College London London, United Kingdom.
Anant R C
ARC
Patel
1 Barts Health NHS Trust London, United Kingdom.|9 * Imperial College London London, United Kingdom.
Richa
R
Singh
3 Imperial College London London, United Kingdom.
Raymond J
RJ
Sapsford
3 Imperial College London London, United Kingdom.
Gavin C
GC
Donaldson
4 Vertex Pharmaceuticals (Europe) Ltd. London, United Kingdom and.|5 * Takeda Development Centre Europe Ltd. London, United Kingdom.
Niyati
N
Prasad
5 * Takeda Development Centre Europe Ltd. London, United Kingdom.|7 Vifor Pharma Ltd. Glattbrugg, Switzerland and.
Udo-Michael
UM
Goehring
6 Takeda Development Centre Europe Ltd. London, United Kingdom.
Tsz Keung
TK
Nip
3 Imperial College London London, United Kingdom.
Jadwiga A
JA
Wedzicha
D000368:Aged; D000369:Aged, 80 and over; D000631:Aminopyridines / Q000627:therapeutic use*; D001549:Benzamides / Q000627:therapeutic use*; D003521:Cyclopropanes / Q000627:therapeutic use; D018450:Disease Progression; D004311:Double-Blind Method; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D007958:Leukocyte Count; D008131:London; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000166:cytology / Q000276:immunology; D058988:Phosphodiesterase 4 Inhibitors / Q000627:therapeutic use*; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology; D013183:Sputum / Q000166:cytology; D016896:Treatment Outcome
D000631:Aminopyridines; D001549:Benzamides; D003521:Cyclopropanes; D058988:Phosphodiesterase 4 Inhibitors; C424423:Roflumilast