Structural analysis of fluorine-containing bioactive glass nanoparticles synthesized by sol-gel route assisted by ultrasound energy.
In the last decades, studies about the specific effects of bioactive glass on remineralization of dentin were the focus of attention, due to their excellent regenerative properties in mineralized tissues. The incorporation of Fluorine in bioactive glass nanoparticles may result in the formation of fluorapatite (FAP), which is chemically more stable than hydroxyapatite or carbonated hydroxyapatite, and therefore is of interest for dental applications. The aim of this study was to synthesize and characterize a new system of Fluorine-containing bioactive glass nanoparticles (BGNPF). A sol-gel route assisted by ultrasound was used for the synthesis of BGNPF. The particles obtained were characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), atomic force microscopy (AFM), X-ray diffraction (XRD), dynamic light scattering (DLS), nitrogen adsorption, and X-ray photoelectron spectroscopy (XPS). SEM micrographs showed that the particles are quite uniform spherical nanostructures, occurring agglomeration or partial sinterization of the particulate system after heat treatment. XRD and XPS analysis results suggest the formation of fluorapatite crystals embedded within the matrix of the bioactive glass nanoparticles. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 360-366, 2018.
Departamento de Engenharia Metalúrgica e de Materiais, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Carolina E C
CEC
Lins
Departamento de Engenharia Metalúrgica e de Materiais, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.|Department of Research and development, JHS Biomateriais, Sabará, Brazil.
Agda A R
AAR
Oliveira
Department of Applied Physics, Centro de Desenvolvimento da Tecnologia Nuclear, CDTN, Belo Horizonte, MG, Brazil.
Ismael
I
Gonzalez
Department of Applied Physics, Centro de Desenvolvimento da Tecnologia Nuclear, CDTN, Belo Horizonte, MG, Brazil.
Waldemar A A
WAA
Macedo
Departamento de Engenharia Metalúrgica e de Materiais, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Marivalda M
MM
Pereira
D005461:Fluorine / Q000737:chemistry*; D005898:Glass / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D044367:Phase Transition; D000069453:Ultrasonic Waves
D005461:Fluorine
bioactive glass; biomaterial; fluorine-containing; material design; nanoparticle