Thrombolysis in peripheral artery disease.
Peripheral artery disease (PAD) has been associated with severe morbidity and mortality worldwide, affecting the quality of life for millions of patients. Acute thrombosis has been identified as a major complication of PAD, with proper management including both open as well as endovascular techniques. Thrombolysis has emerged as a reasonable option in the last decades to treat such patients although data produced by randomized trials have been limited. This review aims to present major aspects of thrombolysis in PAD regarding its indications and contraindications, technique tips as well as to review literature data in order to produce useful conclusions for everyday clinical practice.
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Sotirios
S
Giannakakis
Department of Vascular Surgery, KAT General Hospital, 2 Nikis Street, Kifisia, 14561, Athens, Greece.
George
G
Galyfos
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Ioannis
I
Sachmpazidis
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Kostas
K
Kapasas
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Stavros
S
Kerasidis
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Ioannis
I
Stamatatos
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Georgios
G
Geropapas
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Georgios
G
Kastrisios
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Gerasimos
G
Papacharalampous
Department of Vascular Surgery, KAT General Hospital, Athens, Greece.
Chrisostomos
C
Maltezos
D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D018579:Patient Selection; D058729:Peripheral Arterial Disease / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D011788:Quality of Life; D012307:Risk Factors; D015912:Thrombolytic Therapy / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome; D014654:Vascular Patency / Q000187:drug effects
D005343:Fibrinolytic Agents
peripheral artery disease; review; thrombolysis