Penicillium marneffeiinfection in a HIV-Positive patient: A comparison of bronchial washing cytology and biopsy.
Penicilliosis is a disseminated and progressive infection that is mainly found in immunocompromised individuals, especially those with human immunodeficiency virus (HIV) infection. Because of the high mortality of patients with disseminatedPenicillium marneffeiinfection, rapid diagnosis and early treatment are required. Diagnosis is traditionally made by biopsy and/or culture of blood or any involved organ. Cytology offers several advantages over biopsy, including more rapid diagnosis and greater resolution of cytomorphologic details of organisms, allowing rapid initiation of treatment. Here, we describe a case of penicilliosis in an HIV-positive patient with emphasis on the morphological characteristics of the organism in cytologic specimens, as well as a comparison of bronchial washing and biopsy findings.
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Chu Hyun
CH
Hee
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Chong Young
CY
Pil
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kyung Ja
KJ
Cho
Bronchial washing cytology; HIV; penicilliosis