Premature Ventricular Complex Ablation in Structural Heart Disease.
Frequent premature ventricular complexes (PVCs) in patients with underlying structural heart disease, particular after myocardial infarction, can predict increased mortality. Use of antiarrhythmic medications to suppress PVCs in this setting can result in a further increase in mortality. High PVC burdens in patients with structural heart disease can cause or worsen cardiomyopathy and successful elimination of PVCs with catheter ablation can improve or, in some cases normalize, cardiac function. PVCs may also trigger more malignant ventricular arrhythmias, particularly in patients with previous myocardial infarction, and when identified can be mapped and ablated.
Division of Electrophysiology, Department of Internal Medicine, University of Michigan Health System, CVC, SPC 5853, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5853, USA. Electronic address: rakeshl@med.umich.edu.
Rakesh
R
Latchamsetty
Division of Electrophysiology, Department of Internal Medicine, University of Michigan Health System, CVC, SPC 5853, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5853, USA.
Frank
F
Bogun
D009202:Cardiomyopathies / Q000503:physiopathology / Q000601:surgery; D017115:Catheter Ablation; D006801:Humans; D018879:Ventricular Premature Complexes / Q000503:physiopathology / Q000601:surgery
Ablation; Cardiomyopathy; Premature ventricular complexes; Structural heart disease