Antibiotic use and the prevention and management of infectious complications in stone disease.
The importance of assessing perioperative urine/stone cultures and providing appropriate antibiotic prophylaxis prior to shock wave lithotripsy (SWL) or endoscopic intervention cannot be minimized. Urinary tract infection (UTI) is the most common complication relating to stone intervention. Adequate assessment of culture data and adherence to appropriate guidelines may prevent the development of UTI and the potential for post-intervention urosepsis. This review outlines the current evidence for prophylaxis in the prevention of UTI and urosepsis, as well as the interpretation of stone culture data to provide an evidence-based approach for the judicious use of antibiotics in urologic stone practice.
Division of Urology, Department of Surgery, Duke University Medical Center, 40 Duke Medicine Circle, Room 1573, White Zone, Durham, North Carolina, 27710, USA.
Daniel A
DA
Wollin
St James' University Hospital, Leeds, UK.
Adrian D
AD
Joyce
Mount Sinai Medical Center, New York, NY, USA.
Mantu
M
Gupta
Mount Elizabeth Hospital, Singapore, Singapore.
Michael Y C
MYC
Wong
AMC University of Amsterdam, Amsterdam, The Netherlands.
Pilar
P
Laguna
University of Thessaly, Larissa, Greece.
Stavros
S
Gravas
Wake Forest School of Medicine, Winston-Salem, NC, USA.
Jorge
J
Gutierrez
University of Foggia, Foggia, Italy.
Luigi
L
Cormio
West China Hospital, Sichuan University, Chengdu, China.
Kunjie
K
Wang
Division of Urology, Department of Surgery, Duke University Medical Center, 40 Duke Medicine Circle, Room 1573, White Zone, Durham, North Carolina, 27710, USA. glenn.preminger@duke.edu.
Glenn M
GM
Preminger
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D019317:Evidence-Based Medicine; D006801:Humans; D008096:Lithotripsy / Q000379:methods; D000074642:Nephrolithotomy, Percutaneous / Q000379:methods; D018805:Sepsis / Q000517:prevention & control*; D018666:Ureteroscopy / Q000379:methods; D014545:Urinary Calculi / Q000628:therapy*; D014552:Urinary Tract Infections / Q000517:prevention & control*
D000900:Anti-Bacterial Agents
Antibiotic; Nephrolithiasis; Percutaneous nephrolithotomy; Prophylaxis; Sepsis; Shock wave lithotripsy; Ureteroscopy