Changes in microRNA expression in response to Schistosoma japonicum infection.
Schistosomiasis japonicum is one of the most serious zoonotic diseases in the world. There is increasing evidence to show that host miRNAs are modulated following Schistosoma japonicum infection, and some of these miRNAs may play important regulatory roles in response to schistosome infection. Several host miRNAs have been identified and shown to be potential diagnostic biomarkers or novel therapeutic targets for schistosomiasis. These studies have paved the way to a better understanding of the mechanisms of schistosome-host interaction and may facilitate the development of novel approaches to the control of the disease.
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology, Ministry of Agriculture of China, Shanghai, China.
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Y
Hong
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology, Ministry of Agriculture of China, Shanghai, China.
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Fu
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology, Ministry of Agriculture of China, Shanghai, China.|Department of Clinical Laboratory, Ningbo Municipal Hospital of Traditional Chinese Medicine, Ningbo, China.
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Cao
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology, Ministry of Agriculture of China, Shanghai, China.|Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China.
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0000-0002-7739-6344
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Lin
D056704:Adaptive Immunity / Q000235:genetics* / Q000276:immunology; D000818:Animals; D005786:Gene Expression Regulation / Q000235:genetics*; D006801:Humans; D007113:Immunity, Innate / Q000235:genetics* / Q000276:immunology; D008099:Liver / Q000469:parasitology; D051379:Mice; D035683:MicroRNAs / Q000096:biosynthesis* / Q000235:genetics*; D051381:Rats; D012549:Schistosoma japonicum / Q000276:immunology* / Q000472:pathogenicity; D012554:Schistosomiasis japonica / Q000276:immunology* / Q000469:parasitology
D035683:MicroRNAs
Schistosoma spp; disease; parasite; schistosomiasis