Prevalence of Sensory Neuropathy in Type 2 Diabetes Mellitus and Its Correlation with Duration of Disease.
Background Peripheral neuropathy is one of the most common and distressing late complication of diabetes mellitus. Ignorance of the complications may develop foot ulcers and gangrene requiring amputation. Objective The main objective of this study is to find out the prevalence of sensory neuropathy in type 2 diabetes mellitus and to compare it with the duration of disease. Method Two hundred seventy one patients with type 2 diabetes mellitus of both gender age 30 years and above willing to participate were included in this study. Patients having hypothyroidism, rheumatoid arthritis, B12 deficiency, cerebrovascular disease, chronic musculoskeletal disease, Parkinson's disease, alcohol abuse, chronic renal or liver failure and cancer were excluded from the study. Touch, pin prick and vibration sensation were tested. Vibration perception threshold was recorded from six different sites of the sole of each foot using Biothesiometer. Result Two hundreds seventy one type 2 diabetic outpatients were studied. The mean age was 59.81±22.85 years. The overall prevalence of diabetic sensory neuropathy in the study population was 58.70%. A rising trend of diabetic sensory neuropathy with increasing age and duration of diabetes was observed. Neuropathy was found more in patients having urinary microalbuminuria. Burning and pins and needles sensation were most common symptoms. Conclusion The overall prevalence of diabetic sensory neuropathy in the study population was 58.70% (mean age 59.81±22.85 yrs), and its prevalence increased with duration of diabetes and increasing age. Its prevalence was found more in patients having microalbuminuria.
Department of Cardiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
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Karki
Department of Cardiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
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Yadava
Department of Internal Medicine, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
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Pant
Department of Cardiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
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Thusa
Department of Cardiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
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Dangol
Department of Cardiology, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal.
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Ghimire
D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D003929:Diabetic Neuropathies / Q000453:epidemiology*; D005260:Female; D016523:Foot Ulcer / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010525:Peripheral Nerves / Q000503:physiopathology; D015995:Prevalence; D012307:Risk Factors; D012678:Sensation Disorders / Q000453:epidemiology*