Recent advances in liver transplantation for metabolic disease.
The indications and outcomes of liver transplantation for metabolic disease have been reviewed recently and this short review concentrates on recent developments and advances. Recently recognized metabolic causes of acute liver failure are reviewed and their implications for transplantation discussed. Newly described indications for liver transplantation in systemic metabolic diseases are described and an update is given on the role of auxiliary and domino liver transplantation.
Division of Gastroenterology/Hepatology/Nutrition Children's Hospital of Pittsburgh of UPMC, Pittsburgh Liver Research Centre, University of Pitttsburgh, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA. patrick.mckiernan@chp.edu.
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Mc Kiernan
D000592:Amino Acid Metabolism, Inborn Errors / Q000235:genetics / Q000601:surgery; D000818:Animals; D020739:Brain Diseases, Metabolic, Inborn / Q000235:genetics / Q000601:surgery; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics / Q000601:surgery; D056947:Enzyme Replacement Therapy; D004838:Epiphyses / Q000002:abnormalities / Q000601:surgery; D050938:Glycine N-Methyltransferase / Q000172:deficiency / Q000235:genetics; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000235:genetics / Q000601:surgery; D017114:Liver Failure, Acute / Q000601:surgery*; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation / Q000639:trends*; D008659:Metabolic Diseases / Q000601:surgery*; D017237:Mitochondrial Encephalomyopathies / Q000235:genetics / Q000601:surgery; D039141:Muscular Dystrophy, Oculopharyngeal; D009363:Neoplasm Proteins / Q000235:genetics; D009886:Ophthalmoplegia / Q000151:congenital; D010009:Osteochondrodysplasias / Q000235:genetics / Q000601:surgery; D011693:Purpura / Q000235:genetics / Q000601:surgery; D052919:Refsum Disease, Infantile / Q000235:genetics / Q000601:surgery; D028361:Mitochondrial Diseases
C117339:NBAS protein, human; D009363:Neoplasm Proteins; D050938:Glycine N-Methyltransferase