Assessment of thermal effects in a model of the human head implanted with a wireless active microvalve for the treatment of glaucoma creating a filtering bleb.
A 3D anatomical computational model is developed to assess thermal effects due to exposure to the electromagnetic field required to power a new investigational active implantable microvalve for the treatment of glaucoma. Such a device, located in the temporal superior eye quadrant, produces a filtering bleb, which is included in the geometry of the model, together with the relevant ocular structures. The electromagnetic field source-a planar coil-as well as the microvalve antenna and casing are also included. Exposure to the electromagnetic field source of an implanted and a non-implanted subject are simulated by solving a magnetic potential formulation, using the finite element method. The maximum SAR10is reached in the eyebrow and remains within the limits suggested by the IEEE and ICNIRP standards. The anterior chamber, filtering bleb, iris and ciliary body are the ocular structures where more absorption occurs. The temperature rise distribution is also obtained by solving the bioheat equation with the finite element method. The numerical results are compared with the in vivo measurements obtained from four rabbits implanted with the microvalve and exposed to the electromagnetic field source.
CIMEC Centro de Investigación de Métodos Computacionales, UNL, CONICET, Col. Ruta 168 s/n, Predio CONICET Dr Alberto Cassano, 3000 Santa Fe, Argentina. Facultad de Ingeniera, UNER, Ruta Provincial 11 Km 10, 3100 Oro Verde, Argentina.
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Schaumburg
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Guarnieri
D001768:Blister / Q000503:physiopathology / Q000601:surgery*; D001831:Body Temperature; D004574:Electromagnetic Fields; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D006257:Head / Q000502:physiology* / Q000528:radiation effects; D006801:Humans; D008953:Models, Anatomic; D019736:Prostheses and Implants; D013696:Temperature; D013817:Thermography