A 17-Year-Old With Chest Pain.
A 17-year-old male subject with a history of deep venous thrombosis presented with acute unilateral severe chest pain. His examination was nonspecific, and vital signs were normal. His initial laboratory evaluation revealed mild thrombocytopenia, elevated troponin levels, and critically elevated activated partial thromboplastin time. A computed tomography angiogram of the chest revealed a pulmonary embolus, and anticoagulation therapy was initiated. His course was complicated by the development of multiple thrombi and respiratory failure. Extensive evaluation revealed a rare, underlying diagnosis in time for life-saving treatment to be initiated.
Children's National Health System, Washington, District of Columbia; and anshah@childrensnational.org.
Ankoor Y
AY
Shah
Department of Dermatology, Georgetown University-Washington Hospital Center, Washington, District of Columbia.
Megan
M
Jamison
Children's National Health System, Washington, District of Columbia; and.
Hansel J
HJ
Otero
Children's National Health System, Washington, District of Columbia; and.
Lawrence
L
Jung
Children's National Health System, Washington, District of Columbia; and.
Lowell H
LH
Frank
Children's National Health System, Washington, District of Columbia; and.
Michael F
MF
Guerrera
Children's National Health System, Washington, District of Columbia; and.
A Yasmine
AY
Kirkorian
D000293:Adolescent; D000307:Adrenal Gland Diseases / Q000209:etiology; D016736:Antiphospholipid Syndrome / Q000175:diagnosis*; D002637:Chest Pain / Q000209:etiology; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D008297:Male; D010314:Partial Thromboplastin Time; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging; D013921:Thrombocytopenia / Q000209:etiology; D014336:Troponin / Q000097:blood; D020246:Venous Thrombosis / Q000209:etiology
D016682:Lupus Coagulation Inhibitor; D014336:Troponin