Small Intestinal Bacterial Overgrowth and Other Intestinal Disorders.
Gut microbiota is the largest organ of the human body. Although growth of bacteria more than 105colony forming unit (CFU) per milliliter in culture of upper gut aspirate is used to diagnosis small intestinal bacterial overgrowth (SIBO), 103CFU or more is being considered to suggest the diagnosis, particularly if colonic type bacteria are present in the upper gut. Although neither very sensitive nor specific, hydrogen breath tests are widely used to diagnose SIBO. Rifaximin is the best treatment for SIBO due to its broad spectrum, lack of systemic absorption, and safety profile.
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India. Electronic address: udayghoshal@gmail.com.
Uday C
UC
Ghoshal
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Ujjala
U
Ghoshal
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000254:growth & development*; D000069196:Gastrointestinal Microbiome; D006801:Humans; D007421:Intestine, Small / Q000382:microbiology* / Q000503:physiopathology
D000900:Anti-Bacterial Agents
Gut microbiota; Hydrogen breath tests; Malabsorption syndrome; Rifaximin; Tropical sprue