The Use of Sugammadex in a Patient With Guillain-Barre Syndrome: A Case Report.
Sugammadex encapsulates and inactivates rocuronium and vecuronium. It is used to reverse neuromuscular blockade from these nondepolarizing agents. The safety of sugammadex in patients with neuromuscular disease has not been established. Guillain-Barre Syndrome (GBS) is a neuromuscular disease characterized by acute inflammatory polyneuropathy. Patients with GBS may exhibit autonomic dysfunction, chronic pain, abnormal reactions to neuromuscular blocking agents, and may require postoperative mechanical ventilation. We report the successful use of sugammadex to reverse rocuronium in a patient with chronic GBS, who presented for a hemicolectomy.
From the Department of Anesthesiology and Reanimation Clinic, Turkey Yüksek Ihtisas Education and Research Hospital, Ankara, Turkey.
Büşra
B
Tezcan
Demet
D
Bölükbaşi
Dilek
D
Kazanci
Sema
S
Turan
Gülseren
G
Suer Kaya
Ayşegül
A
Özgök
D000732:Androstanols / Q000037:antagonists & inhibitors; D020275:Guillain-Barre Syndrome / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D003473:Neuromuscular Nondepolarizing Agents / Q000037:antagonists & inhibitors*; D000077123:Rocuronium; D000077122:Sugammadex; D016896:Treatment Outcome; D014673:Vecuronium Bromide / Q000037:antagonists & inhibitors; D047408:gamma-Cyclodextrins / Q000008:administration & dosage* / Q000494:pharmacology
D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D014673:Vecuronium Bromide; D000077123:Rocuronium