Diffuse Nodular Lymphoid Hyperplasia of the Intestine Caused by Common Variable Immunodeficiency and Refractory Giardiasis.
Diffuse nodular lymphoid hyperplasia of the gastrointestinal tract is a rare disease characterized by numerous small polypoid nodules in the small intestine, large intestine, or both. It is associated with immunodeficiency and infection, such as Giardia lamblia and Helicobacter pylori. Although diffuse nodular lymphoid hyperplasia associated with common variable immunodeficiency (CVID) and giardiasis is already known, a few studies have reported a regression of the lymphoid nodules after the eradication of infection. We herein describe a case of diffuse nodular lymphoid hyperplasia of the intestine associated with CVID and refractory giardiasis that markedly improved after successfully treating giardiasis.
Department of Internal Medicine, Hanyang University College of Medicine, Korea.
Jung Hye
JH
Choi
Dong Soo
DS
Han
Jieun
J
Kim
Kijong
K
Yi
Young-Ha
YH
Oh
Yongsoo
Y
Kim
D000328:Adult; D017074:Common Variable Immunodeficiency / Q000150:complications*; D003937:Diagnosis, Differential; D004378:Duodenal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D005260:Female; D005873:Giardiasis / Q000150:complications*; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology