The "Scope" of Post-ERCP Pancreatitis.
Pancreatitis is the most common adverse event of endoscopic retrograde cholangiopancreatography, with the potential for clinically significant morbidity and mortality. Several patient and procedural risk factors have been identified that increase the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). Considerable research efforts have identified several pharmacologic and procedural interventions that can drastically affect the incidence of PEP. This review article addresses the underlying mechanisms at play for the development of PEP, identifying patient and procedural risk factors and meaningful use of risk-stratification information, and details current interventions aimed at reducing the risk of this complication.
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Tulane University, New Orleans, LA.
Parth J
PJ
Parekh
Division of Gastroenterology and Hepatology, University of North Carolina-Johnston Healthcare, Smithfield.
Raj
R
Majithia
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Tulane University, New Orleans, LA.
Sanjay K
SK
Sikka
Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill. Electronic address: todd_baron@med.unc.edu.
Todd H
TH
Baron
D017677:Age Distribution; D018890:Chemoprevention / Q000379:methods; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000209:etiology* / Q000517:prevention & control; D012307:Risk Factors; D017678:Sex Distribution