Magnetic resonance imaging brain findings in a case of aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder, presenting with intractable vomiting and hiccups.
Neuromyelitisoptica (NMO) and multiple sclerosis (MS) were once considered to be differing manifestation of same auto immune disease, NMO predominantly involving the optic nerve and cord. Now with discovery of NMO antibody the concept has changed and a spectrum of disorders with lesions in brain has been identified. Occasionally, brain may be the first or the only site of involvement in these disorders hence it is essential to be aware of this spectrum. The brain lesions in NMO/NMOSD may be located in characteristic regions and present with symptoms mimicking non neurological disease. We herein present a case of an adult female who was admitted with intractable vomiting and hiccups; subsequently on MRI brain found to have very tiny demyelinating foci in Area Postrema.
Department of Radiodiagnosis, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
Prerna
P
Garg
Department of Radiodiagnosis, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
Muthusubramanian
M
Rajasekaran
Department of Radiodiagnosis, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
Salil
S
Pandey
Department of Neurology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
Gnanashanmugam
G
Gurusamy
Department of Radiodiagnosis, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
Devanand
D
Balalakshmoji
Department of Radiodiagnosis, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
Rajakumar
R
Rathinasamy
Aquaporin-4 antibody; area postrema; longitudinally extensive spinal cord lesions; magnetic resonance imaging; multiple sclerosis; neuromyelitis optica; optic neuritis