Highly stable aluminum-based metal-organic frameworks as biosensing platforms for assessment of food safety.
Two unique immunosensors made of aluminum-based metal-organic frameworks (MOFs), namely, 515- and 516-MOFs, with 4,4',4''-nitrilotribenzoic acid (H3NTB) were successfully obtained to efficiently assess food safety. The as-prepared 515- and 516-MOFs exhibited superior thermal and physicochemical stability, high electrochemical activity, and good biocompatibility. Among these immunosensors, 516-MOF showed a preferable biosensing ability toward analytes determined by electrochemical techniques. The developed 516-MOF-based electrochemical biosensor not only demonstrated high sensitivity with low detection limits of 0.70 and 0.40pgmL-1toward vomitoxin and salbutamol, respectively, but also showed good selectivity in the presence of other interferences. Therefore, with the advantages of high sensitivity, good selectivity, and simple operation, this new strategy is believed to exhibit great potential for simple and convenient detection of poisonous and harmful residues in food.
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Chun-Sen
CS
Liu
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Chun-Xiao
CX
Sun
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Jia-Yue
JY
Tian
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Zhuo-Wei
ZW
Wang
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Hong-Fei
HF
Ji
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Ying-Pan
YP
Song
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Shuai
S
Zhang
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China. Electronic address: mainzhh@163.com.
Zhi-Hong
ZH
Zhang
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China.
Ling-Hao
LH
He
Henan Provincial Key Laboratory of Surface & Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China. Electronic address: dumiao@public.tpt.tj.cn.
Miao
M
Du
D000420:Albuterol / Q000032:analysis; D000535:Aluminum / Q000737:chemistry*; D000818:Animals; D055910:Antibodies, Immobilized / Q000737:chemistry; D015374:Biosensing Techniques / Q000379:methods; D001993:Bronchodilator Agents / Q000032:analysis; D055664:Electrochemical Techniques / Q000379:methods*; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D057230:Limit of Detection; D008958:Models, Molecular; D009942:Organometallic Compounds / Q000737:chemistry*; D000069466:Red Meat / Q000032:analysis; D013552:Swine; D014255:Trichothecenes / Q000032:analysis; D014920:Wine / Q000032:analysis
D055910:Antibodies, Immobilized; D001993:Bronchodilator Agents; D009942:Organometallic Compounds; D014255:Trichothecenes; D000535:Aluminum; C007262:deoxynivalenol; D000420:Albuterol
Al-MOF-based electrochemical biosensors; Al-MOFs; Crystal structures; Ultrasensitive detection