Giant Chondroma of the Saddle Area: Case Report and Literature Review.
A 63-year-old man presented with sexual dysfunction of 6-year duration, 5-year history of bilateral vision loss, and left nasal obstruction for 3 years. Brain computed tomography and magnetic resonance imaging showed a large mass lesion in the saddle area and extending upward to the dorsum sellae, bilateral cavernous sinus, and suprasellar region, and down into the sphenoid sinus and nasal cavity; the optic nerves and optic chiasm were elevated upward and compressed. Endocrine tests indicated that all serum level of anterior pituitary hormones decreased. The preoperative diagnosis included invasive pituitary adenoma, chordoma, osteosarcoma, chondrosarcoma, and craniopharyngioma. The tumour was subtotally removed through transsphenoidal approach. Histopathology examination revealed a chondroma. Postoperatively, the patient was stable and his visual acuity and visual field defect improved and his pituitary function return to normal except for hypothyroidism.
Department of Otorhinolaryngology, the Second Hospital of Anhui Medical University Hefei People's Republic of China.
Lubin
L
Qiu
Department of Otorhinolaryngology, the Second Hospital of Anhui Medical University Hefei People's Republic of China.
Yongjun
Y
Zhu
Department of Neurosurgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou People's Republic of China.
Haijun
H
Wang
Department of Otorhinolaryngology, the Second Hospital of Anhui Medical University Hefei People's Republic of China.
Yatang
Y
Wang
Department of Pathology, the Second Hospital of Anhui Medical University Hefei People's Republic of China.
Qiang
Q
Wu
Department of Otorhinolaryngology, the Second Hospital of Anhui Medical University Hefei People's Republic of China.
Jianming
J
Yang
Computed tomography (CT); histology; magnetic resonance (MR); sellar chondroma; transsphenoidal approach