Analgesic Effect of Preoperative Pentazocine for Laparoscopic Cholecystectomy.
Objective:To assess whether preoperative pentazocine can reduce intraoperative hemodynamic changes and postoperative pain. Methods:Fifty patients undergoing laparoscopic cholecystectomy were randomized into two groups. Group P received intravenous 0.5 mg/kg pentazocine 10 min before surgery, and Group C received normal saline as a placebo. A standardized general anesthesia was conducted in all patients. Mean blood pressure (MBP), heart rate (HR), and visual analog scale (VAS) scores at various time points were recorded. The tramadol consumption during the study period was recorded.


RESULTS
Group P had lower VAS scores at two, four, and eight hours postoperatively compared with Group C. MBP and HR rose significantly because of pneumoperitoneum within Group C, and no significant changes were detected in MBP and HR within Group P. Tramadol doses given were statistically fewer in Group P.


CONCLUSIONS
Preoperative intravenous pentazocine can decrease intraoperative hemodynamic changes and postoperative pain.
Department of Anesthesiology, The First Hospital of Jilin University.
Na
N
Wang
Department of Cardiovascular Surgery, The First Hospital of Jilin University.
Lei
L
Wang
Department of Anesthesiology, The First Hospital of Jilin University.
Yang
Y
Gao
Department of Urology, The First Hospital of Jilin University.
Honglan
H
Zhou
Department of Urology, The First Hospital of Jilin University.
Jinguo
J
Wang
laparoscopy; pentazocine; postoperative pain; preemptive analgesia; stress reaction