Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016.
Since early November 2016, the number of laboratory-confirmed norovirus infections reported in Germany has been increasing steeply. Here, we report the detection and genetic characterisation of an emerging norovirus recombinant, GII.P16-GII.2. This strain was frequently identified as the cause of sporadic cases as well as outbreaks in nine federal states of Germany. Our findings suggest that the emergence of GII.P16-GII.2 contributed to rising case numbers of norovirus gastroenteritis in Germany.
Department of Infectious Diseases, Robert Koch-Institute, Berlin, Germany.|Consultant Laboratory for Noroviruses, Robert Koch-Institute, Berlin, Germany.
S
S
Niendorf
Department of Infectious Diseases, Robert Koch-Institute, Berlin, Germany.|Consultant Laboratory for Noroviruses, Robert Koch-Institute, Berlin, Germany.
S
S
Jacobsen
Department for Infectious Disease Epidemiology, Robert Koch-Institute, Berlin, Germany.
M
M
Faber
Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.
A M
AM
Eis-Hübinger
Institute of Medical Virology, Charité University Medicine, Berlin, and Labor Berlin, Charité-Vivantes GmbH, Berlin, Germany.
J
J
Hofmann
Institute of Medical Microbiology, Göttingen, Germany.
O
O
Zimmermann
Department of Infectious Diseases, Robert Koch-Institute, Berlin, Germany.|Consultant Laboratory for Noroviruses, Robert Koch-Institute, Berlin, Germany.
M
M
Höhne
Department of Infectious Diseases, Robert Koch-Institute, Berlin, Germany.
C T
CT
Bock
D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology; D018563:Disease Notification / Q000706:statistics & numerical data; D004196:Disease Outbreaks; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology*; D014644:Genetic Variation; D005838:Genotype; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007223:Infant; D029322:Norovirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D012621:Seasons; D017422:Sequence Analysis, DNA
D012367:RNA, Viral
GII.P16-GII.2; Germany; emergence; norovirus; recombinant