Oncoplastic breast surgery does not delay the onset of adjuvant chemotherapy: a population-based study.
BACKGROUND
Only a few studies of limited size have examined whether oncoplastic breast surgery delays the onset of adjuvant chemotherapy as compared to conventional breast surgery. We investigated whether oncoplastic breast surgery causes a delay in the onset of adjuvant chemotherapy in comparison to lumpectomy and mastectomy.


METHODS
The study is a population-based cohort study. Within the nationwide registry of the Danish Breast Cancer Group (DBCG), we identified 1798 patients who received adjuvant chemotherapy following mastectomy, lumpectomy or oncoplastic breast surgery for early and unilateral invasive breast cancer. Women treated with neoadjuvant chemotherapy were excluded.


RESULTS
We found no significant difference between the three groups (mastectomy, lumpectomy, oncoplastic breast surgery) in the time from biopsy to surgery (mean time 17.9, 17.0 and 18.3 days, respectively), the time from surgery to onset of adjuvant chemotherapy, nor total time from biopsy to the onset of adjuvant chemotherapy (mean time 52.7, 51.9 and 53.2 days, respectively).


CONCLUSIONS
Our study shows that oncoplastic breast surgery does not delay the onset of adjuvant chemotherapy in comparison with mastectomy and lumpectomy. Accordingly, patients should not be excluded from treatment with oncoplastic breast surgery due to concerns of delay in adjuvant chemotherapy.
a Department of Plastic Surgery, Breast Surgery and Burns Treatment , Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
Anders
A
Klit
a Department of Plastic Surgery, Breast Surgery and Burns Treatment , Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
Tove Filtenborg
TF
Tvedskov
a Department of Plastic Surgery, Breast Surgery and Burns Treatment , Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.|b Danish Breast Cancer Group , The Danish Cancer Society , Copenhagen , Denmark.
Niels
N
Kroman
a Department of Plastic Surgery, Breast Surgery and Burns Treatment , Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
Jens Jørgen
JJ
Elberg
b Danish Breast Cancer Group , The Danish Cancer Society , Copenhagen , Denmark.|c Department of Oncology , Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
Bent
B
Ejlertsen
a Department of Plastic Surgery, Breast Surgery and Burns Treatment , Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
Trine Foged
TF
Henriksen
D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016462:Mammaplasty; D008408:Mastectomy; D015412:Mastectomy, Segmental; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D013997:Time Factors