Applications of deuterium oxide in human health.
The main aim goal of this review was to gather information about recent publications related to deuterium oxide (D2O), and its use as a scientific tool related to human health. Searches were made in electronic databases Pubmed, Scielo, Lilacs, Medline and Cochrane. Moreover, the following patent databases were consulted: EPO (Espacenet patent search), USPTO (United States Patent and Trademark Office) and Google Patents, which cover researches worldwide related to innovations using D2O.
a Graduate Programme in Health Sciences , Federal University of São João Del Rei-West Centre Campus , Divinópolis , Brazil.
Wendell Costa
WC
Bila
b Graduate Programme in Biochemistry and Molecular Biology , Federal University of São João del Rei , Divinópolis , Brazil.|c Graduate Program in Biotechnology , Federal University of São João del Rei , Divinópolis , Brazil.
Reysla Maria da Silveira
RMDS
Mariano
d Faculty of Medicine, School of Sciences of Santa Casa de Misericórdia of Vitória , Nossa Senhora da Glória Children's Hospital , Vitória , Brazil.
Valmin Ramos
VR
Silva
a Graduate Programme in Health Sciences , Federal University of São João Del Rei-West Centre Campus , Divinópolis , Brazil.
Maria Emília Soares Martins
MESM
Dos Santos
a Graduate Programme in Health Sciences , Federal University of São João Del Rei-West Centre Campus , Divinópolis , Brazil.
Joel Alves
JA
Lamounier
e Ribeirão Preto Medical School , University of São Paulo , Ribeirão Preto , Brazil.
Eduardo
E
Ferriolli
b Graduate Programme in Biochemistry and Molecular Biology , Federal University of São João del Rei , Divinópolis , Brazil.|c Graduate Program in Biotechnology , Federal University of São João del Rei , Divinópolis , Brazil.
Alexsandro Sobreira
AS
Galdino
D035843:Biomedical Research / Q000379:methods*; D001709:Biotechnology / Q000379:methods*; D017666:Deuterium Oxide / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans
D017666:Deuterium Oxide
Application research; deuterium oxide; human health; hydrogen-2; isotope biochemistry; isotope effects; patents; stable isotope pharmaceuticals