Laryngeal Dysplasia, Squamous Cell Carcinoma, and Variants.
Squamous cell carcinoma (SCC) is a malignant epithelial tumor showing evidence of squamous differentiation. It is the most common malignancy of the larynx, with several variants (verrucous, exophytic or papillary, spindle-cell, basaloid, acantholytic, adenosquamous) recognized, with well-established precursor lesions. Dysplasia is now separated into only low-grade and high-grade categories. Each SCC variant has unique cytomorphologic features and histologic differential diagnoses that are important to consider, as management and outcomes are different.
Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, 5601 De Soto Avenue, Woodland Hills, CA 91367, USA. Electronic address: Lester.D.Thompson@kp.org.
Lester D R
LD
Thompson
D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D060787:Neoplasm Grading; D011230:Precancerous Conditions / Q000175:diagnosis / Q000473:pathology*
Carcinoma, adenosquamous; Carcinoma, squamous cell; Carcinoma, verrucous; Dysplasia; Larynx