Checking rounds for isolation precautions in the control of multidrug-resistant organisms: reduction achieved.
The objective of this investigation was to analyze the effectiveness of a quality improvement initiative in limiting the spread of multidrug-resistant organisms (MDROs) in the hospital setting. During the period 2011-2013, a multimodal intervention was activated at a tertiary care center in Italy. The intervention included: laboratory-based surveillance, interdisciplinary training sessions, monitoring the adoption of isolation precautions and daily supervision provided by infection control nurses, and a monthly feedback. Time series analysis was used to evaluate the trends and correlations between the MDROs rate, intensity of checking rounds, and hospital-wide data (i.e., transfer of patients, patients' days, site of isolation, etc.). A total of 149,251 patients were included in the study. The proportion of patients undergoing transmission-based isolation precautions within 24 h from a positive laboratory finding increased from 83% in 2011 to 99% in 2013 (p < 0.05). The wards appropriately adopting the correct isolation precaution increased from 83% in 2011 to 97.6% in 2013 (p < 0.05). The frequency of controls was significantly reduced after the observation of compliance in the appropriate wards (p < 0.05). After three years, the incidence rate changed from 5.8/1000 days of stay [95% confidence interval (CI) 5.6-6.1] in 2011 to 4.7 (95% CI 4.4-4.9) in 2013 (p < 0.0001). Moreover, microorganisms isolated from different types of specimens showed variable potential for transmission (i.e., skin as the most potential and urine the least). The results demonstrate the efficacy of the multimodal intervention, with sustained reduction of MDROs rate, besides check reduction, and highlight the long-term efficacy of checking rounds in changing professionals' behaviors.
Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Ancona, Italy.
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Barbadoro
Azienda Ospedaliero Universitaria "Ospedali Riuniti", Ancona, Italy.
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Martini
Azienda Ospedaliero Universitaria "Ospedali Riuniti", Ancona, Italy.
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Gioia
Azienda Ospedaliero Universitaria "Ospedali Riuniti", Ancona, Italy.
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Stoico
Azienda Ospedaliero Universitaria "Ospedali Riuniti", Ancona, Italy.
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Savini
Azienda Ospedaliero Universitaria "Ospedali Riuniti", Ancona, Italy.
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Manso
Azienda Ospedaliero Universitaria "Ospedali Riuniti", Ancona, Italy.
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Serafini
Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Ancona, Italy.
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Prospero
Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Ancona, Italy. musa@univpm.it.|Azienda Ospedaliero Universitaria "Ospedali Riuniti", Ancona, Italy. musa@univpm.it.|Department of Biomedical Sciences and Public Health, Hospital Hygiene Unit, AOU Ancona United Hospitals, Università Politecnica delle Marche, via Tronto, 10/a, Torrette di Ancona, Italy, 60020. musa@univpm.it.
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D'Errico
D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D024901:Drug Resistance, Multiple, Bacterial; D062665:Epidemiological Monitoring; D006761:Hospitals; D006801:Humans; D015994:Incidence; D017053:Infection Control / Q000379:methods*; D007558:Italy / Q000453:epidemiology; D062606:Tertiary Care Centers