Surgical safety analysis of retaining the glands in papillary thyroid microcarcinoma.
The objective of the present study was to analyze the surgical safety of retaining the glands in papillary thyroid microcarcinoma (mPTC).



156 cases of mPTC were retrospectively reviewed and divided into four groups according to the treatment: group A (conservative follow-up group, 30 cases), group B (total resection of unilateral gland combined with isthmic resection, 48 cases), group C (total resection of unilateral gland combined with subtotal resection of contralateral gland, 47 cases), and group D (total resection of bilateral glands, 31 cases). The average follow-up time was 34.5 months.



The occurrence rate of hypothyroidism, hypoparathyroidism, hypocalcemia, injury of the recurrent laryngeal nerve and total occurrence rate in the group B were significantly lower than in the group C and group D, and the differences were statistically significant (p<0.05). The 75% survival time was 33 months in group A, 35 months in group B, and 34 months in group D. The survival time of group A was significantly less than in the other groups, and the difference was statistically significant (p<0.001). There was no significant difference in the comparison of total mortality rate and recurrence rate (p>0.05).



The total resection of the unilateral gland combined with isthmic resection, which conserves gland functionality, reduces complications and maintains survival time. It is, therefore, worthy of further clinical application.
The Third General Surgery, The Central Hospital of Zhumadian City, Zhumadian City, China. sprescbha7@163.com.
B
B
Ding
J-F
JF
Yu
W
W
Sun
N-F
NF
Ma
D000328:Adult; D002291:Carcinoma, Papillary / Q000601:surgery*; D005260:Female; D006801:Humans; D007011:Hypoparathyroidism / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D059351:Organ Sparing Treatments; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy