The Role of Liver Function in the Setting of Cirrhosis with Chronic Infection and Critical Illness.
The patient with sepsis in the setting of hepatitis C virus (HCV)-related cirrhosis can have a more rapid decline in other organ dysfunction during critical illness and faces further increase in the risk for death. This article discusses the role of liver function in the patient with a systemic critical illness in contrast to the worsened pathophysiology of the patient with cirrhosis secondary to chronic HCV infection and critical illness, inpatient and posthospitalization management of the critically ill patient with chronic HCV-related cirrhosis, and the nursing implications and recommendations for future research for this population.
School of Nursing, Louisiana State University Health Sciences Center, 1900 Gravier Street, New Orleans, LA 70112, USA. Electronic address: Slee17@lsuhsc.edu.
Susan
S
Lee
School of Nursing, Louisiana State University Health Sciences Center, 1900 Gravier Street, New Orleans, LA 70112, USA.
Latanja
L
Divens
School of Nursing, Louisiana State University Health Sciences Center, 1900 Gravier Street, New Orleans, LA 70112, USA.
Leanne H
LH
Fowler
D000998:Antiviral Agents / Q000627:therapeutic use*; D064648:Critical Care Nursing; D016638:Critical Illness / Q000451:nursing; D019698:Hepatitis C, Chronic / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D008103:Liver Cirrhosis / Q000503:physiopathology*; D018805:Sepsis / Q000401:mortality / Q000503:physiopathology*
D000998:Antiviral Agents
Cirrhosis; Critical illness; Hepatitis C virus; Nurse practitioner; Nursing; Sepsis