Severe Chromoblastomycosis-Like Cutaneous Infection Caused byChrysosporium keratinophilum.
Chrysosporiumspecies are saprophytic filamentous fungi commonly found in the soil, dung, and animal fur. Subcutaneous infection caused by this organism is rare in humans. We report a case of subcutaneous fungal infection caused byChrysosporium keratinophilumin a 38-year-old woman. The patient presented with severe chromoblastomycosis-like lesions on the left side of the jaw and neck for 6 years. She also got tinea corporis on her trunk since she was 10 years old.Chrysosporium keratinophilumwas isolated from the tissue on the neck and scales on the trunk, respectively. The patient showed satisfactory response to itraconazole therapy, although she discontinued the follow-up.
Department of Dermatology, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi, China.
Juhaer
J
Mijiti
Department of Dermatology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China; Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China.
Bo
B
Pan
CBS-KNAW Fungal Biodiversity Centre, Royal Netherlands Academy of Arts and Sciences Utrecht, Netherlands.
Sybren
S
de Hoog
Medical Mycology Research Center, Chiba University Chiba, Japan.
Yoshikazu
Y
Horie
Department of Nutrition Science, University of Nagasaki Nagasaki, Japan.
Tetsuhiro
T
Matsuzawa
Department of Dermatology, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi, China.
Yilixiati
Y
Yilifan
Department of Dermatology, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi, China.
Yong
Y
Liu
Department of Dermatology, First Hospital of Xinjiang Medical University Urumqi, China.
Parida
P
Abliz
Department of Dermatology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China; Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China.
Weihua
W
Pan
Department of Dermatology, The Second Affiliated Hospital of Kunming Medical University Kunming, China.
Danqi
D
Deng
Department of Dermatology, The Second Affiliated Hospital of Kunming Medical University Kunming, China.
Yun
Y
Guo
Department of Dermatology, The Second Affiliated Hospital of Kunming Medical University Kunming, China.
Peiliang
P
Zhang
Department of Dermatology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China; Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China.
Wanqing
W
Liao
Department of Dermatology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China; Key Laboratory of Molecular Medical Mycology, Shanghai Changzheng Hospital, Second Military Medical UniversityShanghai, China; Department of Dermatology, First Hospital of Xinjiang Medical UniversityUrumqi, China.
Shuwen
S
Deng
Chrysosporium keratinophilum; cutaneous infection; diagnosis; fungal infection; treatment