[Fever and hypotension after treatment of syphilis; the Jarisch-Herxheimer reaction].
A 73-year-old man presented with fever and hypotension, which had developed a few hours after receiving treatment with benzyl-penicillin for secondary syphilis. These symptoms were due to the so-called Jarisch-Herxheimer reaction. The patient was admitted to hospital and treated with prednisone and intravenous fluids. Within 24 hours the patient had fully recovered. The symptoms, pathogenesis and treatment of Jarisch-Herxheimer reaction are discussed.
Amphia Ziekenhuis, afd. Inwendige Geneeskunde, Breda.
K D
KD
Hendriks
R W
RW
van Etten
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P
van Wijngaarden
D000368:Aged; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D007022:Hypotension / Q000139:chemically induced*; D008297:Male; D010400:Penicillin G / Q000009:adverse effects* / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D013587:Syphilis / Q000188:drug therapy*
D010400:Penicillin G; D011241:Prednisone