Supramolecular Metal-Coordination Polymers, Nets, and Frameworks from Synthetic Coiled-Coil Peptides.
Metal coordination and peptide-directed self-assembly are two proven methods for creating defined supramolecular architectures. Here, we report a new class of crystalline materials based on coiled-coil peptides bearing unnatural metal-chelating terpyridine moieties. High-resolution structural characterization of lattices formed in the presence of Cu2+reveals a general assembly mechanism. Subtle sequence variation in the modular synthetic ligand dictates assembly morphology.
Department of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.
Nathan A
NA
Tavenor
Department of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.
Matthew J
MJ
Murnin
Department of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.
W Seth
0000-0003-2927-1739
WS
Horne
D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D046911:Macromolecular Substances; D008958:Models, Molecular; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
D056831:Coordination Complexes; D008024:Ligands; D046911:Macromolecular Substances; D010455:Peptides; D011108:Polymers; D003300:Copper