[Genital warts in HIV-infected individuals].
Anogenital warts (condylomata acuminata) are much more frequent in human immunodeficiency (HIV)-positive patients compared to HIV-negative individuals. Anogenital warts of HIV-infected patients differ from those of HIV-negative individuals with respect to their spread, occurrence on more unusual anatomical sites, human papillomavirus (HPV)-type spectrum, tendency to recur, and risk of malignant transformation. Between 18 and 56% of anogenital warts of HIV-positive patients harbor high-grade dysplasia. Therefore, anogenital warts of HIV-infected patients should be preferentially treated with ablative methods and should be evaluated histopathologically. Gender-neutral prophylactic HPV vaccination of HPV-naive boys and girls could also lead to a significant reduction of anogenital warts in this patient group in the future.
Institut für Virologie, Nationales Referenzzentrum für Papillom- und Polyomaviren, Universität zu Köln, 50935, Köln, Deutschland. ulrike.wieland@uni-koeln.de.
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Wieland
Klinik für Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Klinik Oberhausen, Universität Witten-Herdecke, 46045, Oberhausen, Deutschland.
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Kreuter
D003218:Condylomata Acuminata / Q000175:diagnosis* / Q000628:therapy* / Q000821:virology; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D015658:HIV Infections / Q000175:diagnosis* / Q000628:therapy* / Q000821:virology; D006801:Humans; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000517:prevention & control / Q000821:virology*; D011230:Precancerous Conditions / Q000175:diagnosis / Q000517:prevention & control / Q000821:virology*; D016896:Treatment Outcome
Anogenital warts; Condylomata acuminata; Genital warts; Human papillomavirus; Vaccination