Acute effects of nicotine-free and flavour-free electronic cigarette use on lung functions in healthy and asthmatic individuals.
We designed a crossover and placebo-controlled trial to investigate the impact of a 1-h acute vaping session of nicotine-free and flavour-free e-liquid on the pulmonary functions and respiratory mechanics of healthy and asthmatic individuals. This study shows that a 1-h vaping session of a high-grade and contaminant-free mixture of propylene glycol and glycerol using a commercially available electronic cigarette performed in a controlled environment does not significantly impact pulmonary functions, respiratory mechanics or symptoms in healthy or asthmatic subjects.
Quebec Heart and Lung Institute - Université Laval, 2725 Chemin Sainte-Foy, Quebec City, PQ, G1V 4G5 Mallet M2679, Canada.
Marie-Ève
MÈ
Boulay
Quebec Heart and Lung Institute - Université Laval, 2725 Chemin Sainte-Foy, Quebec City, PQ, G1V 4G5 Mallet M2679, Canada.
Cyndi
C
Henry
Quebec Heart and Lung Institute - Université Laval, 2725 Chemin Sainte-Foy, Quebec City, PQ, G1V 4G5 Mallet M2679, Canada.|Department of Medicine, Université Laval, Quebec City, Canada.
Ynuk
Y
Bossé
Quebec Heart and Lung Institute - Université Laval, 2725 Chemin Sainte-Foy, Quebec City, PQ, G1V 4G5 Mallet M2679, Canada.
Louis-Philippe
LP
Boulet
Quebec Heart and Lung Institute - Université Laval, 2725 Chemin Sainte-Foy, Quebec City, PQ, G1V 4G5 Mallet M2679, Canada. mathieu.morissette@criucpq.ulaval.ca.|Department of Medicine, Université Laval, Quebec City, Canada. mathieu.morissette@criucpq.ulaval.ca.
Mathieu C
MC
Morissette
D000280:Administration, Inhalation; D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D018592:Cross-Over Studies; D005260:Female; D005990:Glycerol / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D009538:Nicotine; D015990:Placebo Effect; D019946:Propylene Glycol / Q000008:administration & dosage / Q000009:adverse effects*; D012129:Respiratory Function Tests; D000072137:Vaping / Q000009:adverse effects*
D019946:Propylene Glycol; D009538:Nicotine; D005990:Glycerol