Opening new horizons in regenerative dermatology using platelet-based autologous therapies.
Biological therapeutic therapies are gaining the attention of scientists and medical doctors. Accumulating evidence suggests that blood-derived autologous therapies are safe and effective treatments for skin repair and wound healing. The fibrin network formed after plasmatic activation and the autologous growth factors released when platelets degranulate constitute a real biological medicine that has been shown to promote cell recruitment, stimulate new blood vessel formation, reduce inflammation as well as protect from local infections. This perspective highlights recent basic and clinical results published on blood-derived autologous therapies in the field of regenerative dermatology and discusses potential challenges and future prospects.
Eduardo Anitua Foundation for Biomedical Research, Vitoria, Spain.|BTI - Biotechnology Institute, Vitoria, Spain.
Eduardo
E
Anitua
BTI - Biotechnology Institute, Vitoria, Spain.
Ander
A
Pino
Eduardo Anitua Foundation for Biomedical Research, Vitoria, Spain.|Laboratory of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of the Basque Country, Vitoria, Spain.|Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, SLFPB-EHU, Vitoria, Spain.
Gorka
G
Orive
D001792:Blood Platelets; D003357:Cosmetic Techniques; D006801:Humans; D017713:Platelet Transfusion; D012038:Regeneration; D012879:Skin Physiological Phenomena; D014182:Transplantation, Autologous; D014945:Wound Healing