Epilepsy: HSP90 inhibition suppresses seizures.
Sarah
S
Crunkhorn
D000818:Animals; D016227:Benzoquinones; D004827:Epilepsy / Q000188:drug therapy* / Q000378:metabolism*; D050491:Glutamate Plasma Membrane Transport Proteins / Q000378:metabolism; D018841:HSP90 Heat-Shock Proteins / Q000037:antagonists & inhibitors*; D006801:Humans; D047029:Lactams, Macrocyclic; D051379:Mice; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D012640:Seizures / Q000188:drug therapy* / Q000378:metabolism
D016227:Benzoquinones; D050491:Glutamate Plasma Membrane Transport Proteins; D018841:HSP90 Heat-Shock Proteins; D047029:Lactams, Macrocyclic; C112765:tanespimycin; D046988:Proteasome Endopeptidase Complex