Specific detection of cancer cells through aggregation-induced emission of a light-up bioprobe.
A cancer cell specific aptamer was labeled with an aggregation-induced emission (AIE) probe for the first time. Using it as a light-up bioprobe, a specific cancer cell detection method is developed.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. hpzhou@ciac.ac.cn congyu@ciac.ac.cn and University of the Chinese Academy of Sciences, Beijing 100049, P. R. China.
Jian
J
Chen
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. hpzhou@ciac.ac.cn congyu@ciac.ac.cn and University of the Chinese Academy of Sciences, Beijing 100049, P. R. China.
Hong
H
Jiang
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. hpzhou@ciac.ac.cn congyu@ciac.ac.cn and University of the Chinese Academy of Sciences, Beijing 100049, P. R. China.
Huipeng
H
Zhou
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. hpzhou@ciac.ac.cn congyu@ciac.ac.cn and University of the Chinese Academy of Sciences, Beijing 100049, P. R. China.
Zhenzhen
Z
Hu
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. hpzhou@ciac.ac.cn congyu@ciac.ac.cn and University of the Chinese Academy of Sciences, Beijing 100049, P. R. China.
Niu
N
Niu
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. hpzhou@ciac.ac.cn congyu@ciac.ac.cn and Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan. sashahzad@ciit.net.pk.
Sohail Anjum
SA
Shahzad
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. hpzhou@ciac.ac.cn congyu@ciac.ac.cn and University of the Chinese Academy of Sciences, Beijing 100049, P. R. China.
Cong
C
Yu
D052157:Aptamers, Nucleotide / Q000737:chemistry*; D045744:Cell Line, Tumor; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D008856:Microscopy, Fluorescence / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D061848:Optical Imaging / Q000379:methods; D013050:Spectrometry, Fluorescence / Q000379:methods
D052157:Aptamers, Nucleotide; D005456:Fluorescent Dyes