title: Do TMJ symptoms improve and last across time after treatment with red (660 nm) and infrared (790 nm) low level laser treatment (LLLT)? A survival analysis.
abstract: OBJECTIVE
  Temporomandibular disorder (TMD) is a variety of clinical problems that originate from the area of the temporomandibular joint (TMJ), masticatory muscles, and surrounding tissues. There are different treatment options; however, there is no evidence that low level laser treatment (LLLT) will last about six months. The aim of this study was to determine the survival rate of treatment with red (660 nm) and infrared (790 nm) laser in cases of TMDs.
  
  
  METHODS
  In 19 subjects, one side of the face (half face) was randomly selected to receive intervention, in a total of 116 sensitive points. Pain was measured at baseline and time intervals of 24 h, 30, 90, and 180 days after treatment. Laser irradiation with 4 j/cm² in the TMJs and 8 j/cm² in the muscles was used in three sessions. Kaplan-Meier survival analysis and logistic regression were performed.
  
  
  RESULTS
  Both treatments showed statistically significant results (p < 0.001). The survival rate for red and infrared laser was 0.24 and 0.30, respectively, at 180 days. Grinding teeth and headache were associated with recurrent pain.
  
  
  CONCLUSIONS
  Both lasers were effective in the treatment of TMD symptoms and had a low survival rate at 180 days.
authors.affiliation: a Faculty of Dentistry, Department of Periodontology , Federal University of Minas Gerais , Belo Horizonte , Brazil.
authors.forename: Dhelfeson Willya
authors.identifier: http://orcid.org/0000-0002-8628-3122
authors.initials: DW
authors.lastname: Douglas De Oliveira
authors.affiliation: a Faculty of Dentistry, Department of Periodontology , Federal University of Minas Gerais , Belo Horizonte , Brazil.
authors.forename: Frederico Santos
authors.initials: FS
authors.lastname: Lages
authors.affiliation: b Private Practice , Montes Claros , Brazil.
authors.forename: Raphael Castro
authors.initials: RC
authors.lastname: Guimarães
authors.affiliation: b Private Practice , Montes Claros , Brazil.
authors.forename: Túlio Silva
authors.identifier: http://orcid.org/0000-0002-7520-4759
authors.initials: TS
authors.lastname: Pereira
authors.affiliation: c Department of Dentistry , Federal University of Jequitinhonha and Mucuri Valley , Diamantina , Brazil.
authors.forename: Adriana Maria
authors.initials: AM
authors.lastname: Botelho
authors.affiliation: c Department of Dentistry , Federal University of Jequitinhonha and Mucuri Valley , Diamantina , Brazil.
authors.forename: José Cristiano Ramos
authors.identifier: http://orcid.org/0000-0002-7991-1012
authors.initials: JCR
authors.lastname: Glória
authors.affiliation: c Department of Dentistry , Federal University of Jequitinhonha and Mucuri Valley , Diamantina , Brazil.
authors.forename: Karine Taís Aguiar
authors.initials: KTA
authors.lastname: Tavano
authors.affiliation: c Department of Dentistry , Federal University of Jequitinhonha and Mucuri Valley , Diamantina , Brazil.
authors.forename: Patricia Furtado
authors.initials: PF
authors.lastname: Gonçalves
authors.affiliation: c Department of Dentistry , Federal University of Jequitinhonha and Mucuri Valley , Diamantina , Brazil.
authors.forename: Olga Dumont
authors.initials: OD
authors.lastname: Flecha
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D016019:Survival Analysis; D013705:Temporomandibular Joint Disorders / Q000532:radiotherapy*; D016896:Treatment Outcome
keywords: Laser; orofacial pain; photobiomodulation; survival analysis; temporomandibular disorders