title: Synthetic (polymer) biology (membrane): functionalization of polymer scaffolds for membrane proteins.
abstract: A plethora of polymer-based scaffolds have been designed to facilitate biochemical and biophysical investigation of membrane proteins, with a common goal to stabilize and present them in a functional format. In this review, an up-to-date account of such polymer-based supports and incorporation methodologies are presented. Furthermore, conceptual and imminent technological advances, with associated technical challenges are proposed.
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Drive, 637553, Singapore.
authors.forename: Zhaolong
authors.initials: Z
authors.lastname: Hu
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Drive, 637553, Singapore.
authors.forename: James C S
authors.initials: JCS
authors.lastname: Ho
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Drive, 637553, Singapore; ACM Biolabs Pte Ltd., Innovation Centre Block 2, 18 Nanyang Drive, 637723, Singapore. Electronic address: MNallani@ntu.edu.sg.
authors.forename: Madhavan
authors.initials: M
authors.lastname: Nallani
mesh_terms: D006801:Humans; D008565:Membrane Proteins / Q000737:chemistry*; D008567:Membranes, Artificial; D011108:Polymers / Q000737:chemistry*; D058615:Synthetic Biology / Q000379:methods*
chemical_list: D008565:Membrane Proteins; D008567:Membranes, Artificial; D011108:Polymers