title: Transduction Function of a Magnetic Nanoparticle TMADM for Stem-Cell Imaging with Quantum Dots.
abstract: We investigated the transduction function of a cationic dextran hydroxypropyltrimethyl ammonium chloride-coated magnetic iron oxide nanoparticle (TMADM-03) for transducing quantum dots (QDs) into adipose tissue-derived stem cells (ASCs). As a result, the fluorescence intensity of ASCs labeled with QDs using TMADM-03 was much higher than that of QDs only labeling. These data suggest that TMADM-03 can be useful as a transduction agent for QDs in stem-cell imaging.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Nagoya University.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Ogihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yukawa
authors.forename: Daisuke
authors.initials: D
authors.lastname: Onoshima
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Baba
mesh_terms: D000273:Adipose Tissue / Q000166:cytology; D000818:Animals; D003911:Dextrans / Q000737:chemistry*; D005260:Female; D005290:Ferric Compounds / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D057054:Molecular Imaging / Q000379:methods*; D061848:Optical Imaging / Q000379:methods*; D020005:Propanols / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013234:Stem Cells / Q000166:cytology*
chemical_list: D003911:Dextrans; D005290:Ferric Compounds; D020005:Propanols; D000644:Quaternary Ammonium Compounds; C000499:ferric oxide