title: Flavoalkaloids-Isolation, Biological Activity, and Total Synthesis.
abstract: The flavoalkaloids possess unique molecular frameworks that contain both a flavonoid and alkaloid component. Flavoalkaloids result from the convergence of distinct biosynthetic pathways, affording natural products that display a wide range of interesting biological activities that would not be expected for flavonoids or alkaloids alone. This chapter collates all the known flavoalkaloids up until early 2016, detailing their isolation, bioactivity, and successful total syntheses.
authors.affiliation: University of Auckland, Auckland, New Zealand.
authors.forename: Lachlan M
authors.initials: LM
authors.lastname: Blair
authors.affiliation: University of Auckland, Auckland, New Zealand.
authors.forename: Matthew B
authors.initials: MB
authors.lastname: Calvert
authors.affiliation: University of Auckland, Auckland, New Zealand.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Sperry
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis / Q000302:isolation & purification / Q000494:pharmacology; D001688:Biological Products; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D001688:Biological Products
keywords: Alkaloid; Biologically active molecules; Flavoalkaloid; Flavonoid; Natural product; Total synthesis