title: Structural analysis of strontium in human teeth treated with surface pre-reacted glass-ionomer filler eluate by using extended X-ray absorption fine structure analysis.
abstract: The bioactive effects of strontium released from surface pre-reacted glass-ionomer (S-PRG) fillers may aid in caries prevention. In this study, the local structure of strontium taken up by teeth was estimated by extended X-ray absorption fine structure analysis. Immersing teeth into S-PRG filler eluate increased the strontium content in enamel and dentin by more than 100 times. The local structure of strontium in enamel and dentin stored in distilled water was the same as that in synthetic strontium-containing hydroxyapatite (SrHAP). Moreover, the local structure of strontium in enamel and dentin after immersion in the S-PRG filler eluate was also similar to that of SrHAP. After immersion in the S-PRG filler eluate, strontium was suggested to be incorporated into the hydroxyapatite (HAP) of enamel and dentin at the calcium site in HAP.
authors.affiliation: Advanced Biomaterials Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.
authors.forename: Motohiro
authors.initials: M
authors.lastname: Uo
authors.forename: Takahiro
authors.initials: T
authors.lastname: Wada
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Asakura
mesh_terms: D003743:Dental Enamel; D003804:Dentin; D005899:Glass Ionomer Cements; D006801:Humans; D013324:Strontium; D014965:X-Rays
chemical_list: D005899:Glass Ionomer Cements; D013324:Strontium