title: Initial Experience with a Cone-beam Breast Computed Tomography-guided Biopsy System.
abstract: OBJECTIVE
  To evaluate our initial experience with a cone-beam breast computed tomography (BCT)-guided breast biopsy system for lesion retrieval in phantom studies for use with a cone-beam BCT imaging system.
  
  
  METHODS
  Under the Institutional Review Board approval, a phantom biopsy study was performed using a dedicated BCT-guided biopsy system. Fifteen biopsies were performed on each of the small, medium, and large anthropomorphic breast phantoms with both BCT and stereotactic guidance for comparison. Each set of the 45 phantoms contained masses and calcification clusters of varying sizes. Data included mass/calcium retrieval rate and dose and length of procedure time for phantom studies.
  
  
  RESULTS
  Phantom mass and calcium retrieval rate were 100% for BCT and stereotactic biopsy. BCT dose for small and medium breast phantoms was found to be equivalent to or less than the corresponding stereotactic approach. Stereotactic-guided biopsy dose was 34.2 and 62.5 mGy for small and medium breast phantoms, respectively. BCT-guided biopsy dose was 15.4 and 30.0 mGy for small and medium breast phantoms, respectively. Both computed tomography biopsy and stereotactic biopsy study time ranged from 10 to 20 min.
  
  
  CONCLUSIONS
  Initial experience with a BCT-guided biopsy system has shown to be comparable to stereotactic biopsy in phantom studies with equivalent or decreased dose.
authors.affiliation: Elizabeth Wende Breast Care, LLC, Rochester, NY, USA.
authors.forename: Posy J
authors.initials: PJ
authors.lastname: Seifert
authors.affiliation: Elizabeth Wende Breast Care, LLC, Rochester, NY, USA.
authors.forename: Renee C
authors.initials: RC
authors.lastname: Morgan
authors.affiliation: Radiation Safety Unit, University of Rochester, Rochester, NY, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Conover
authors.affiliation: Elizabeth Wende Breast Care, LLC, Rochester, NY, USA.
authors.forename: Andrea L
authors.initials: AL
authors.lastname: Arieno
keywords: Breast biopsy; breast cancer; breast computed tomography