title: Semi-classical statistical description of Fröhlich condensation.
abstract: Fröhlich's model equations describing phonon condensation in open systems of biological relevance are reinvestigated within a semi-classical statistical framework. The main assumptions needed to deduce Fröhlich's rate equations are identified and it is shown how they lead us to write an appropriate form for the corresponding master equation. It is shown how solutions of the master equation can be numerically computed and can highlight typical features of the condensation effect. Our approach provides much more information compared to the existing ones as it allows to investigate the time evolution of the probability density function instead of following single averaged quantities. The current work is also motivated, on the one hand, by recent experimental evidences of long-lived excited modes in the protein structure of hen-egg white lysozyme, which were reported as a consequence of the condensation effect, and, on the other hand, by a growing interest in investigating long-range effects of electromagnetic origin and their influence on the dynamics of biochemical reactions.
authors.affiliation: Department of Oncology, 3-336, Cross Cancer Institute, Edmonton, AB, T6G 1Z2, Canada. preto@ualberta.ca.
authors.forename: Jordane
authors.identifier: http://orcid.org/0000-0002-6041-4008
authors.initials: J
authors.lastname: Preto
mesh_terms: D008962:Models, Theoretical; D013223:Statistics as Topic; D013816:Thermodynamics
keywords: Far-from-equilibrium systems; Fröhlich condensation; Low-frequency modes of proteins