title: Cancer Bioinformatics for Updating Anticancer Drug Developments and Personalized Therapeutics.
abstract: Last two to three decades, this world witnesses a rapid progress of biomarkers and bioinformatics technologies. Cancer bioinformatics is one of such important omics branches for experimental/clinical studies and applications.
  
  
  
  Same as other biological techniques or systems, bioinformatics techniques will be widely used. But they are presently not omni-potent. Despite great popularity and improvements, cancer bioinformatics has its own limitations and shortcomings at this stage of technical advancements.
  
  
  
  This article will offer a panorama of bioinformatics in cancer researches and clinical therapeutic applications-possible advantages and limitations relating to cancer therapeutics. A lot of beneficial capabilities and outcomes have been described. As a result, a successful new era for cancer bioinformatics is waiting for us if we can adhere on scientific studies of cancer bioinformatics in malignant- origin mining, medical verifications and clinical diagnostic applications.
  
  
  
  Cancer bioinformatics gave a great significance in disease diagnosis and therapeutic predictions. Many creative ideas and future perspectives are highlighted.
authors.affiliation: Shanghai University, Shanghai 200444, China.
authors.forename: Da-Yong
authors.initials: DY
authors.lastname: Lu
authors.affiliation: Nanjing General Hospital of Nanjing Military Command, Jiangsu Province, China.
authors.forename: Rong-Xin
authors.initials: RX
authors.lastname: Qu
authors.affiliation: Shanghai University, Shanghai 200444, China.
authors.forename: Ting-Ren
authors.initials: TR
authors.lastname: Lu
authors.affiliation: Shanghai University, Shanghai 200444, China.
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Wu
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D035843:Biomedical Research / Q000379:methods; D019295:Computational Biology / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D058990:Molecular Targeted Therapy / Q000379:methods*; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics; D057285:Precision Medicine / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D000970:Antineoplastic Agents
keywords: Cancer bioinformatics; cancer stem cells; cancer therapy; drug developments; drug response predictions; neoplasm
  metastasis; personalized cancer therapy