title: Periodontal Regenerative Therapy of Intrabony Defects Using Deproteinized Bovine Bone Mineral in Combination with Collagen Barrier Membrane: A Multicenter Prospective Case-Series Study.
abstract: This multicenter prospective case series study aimed to evaluate the outcome of periodontal regenerative therapy using a deproteinized bovine bone mineral (DBBM) in combination with a collagen barrier (CB) in the treatment of intrabony defects. A total of 36 nonsmoking patients with chronic periodontitis were recruited in five centers in Japan. All patients had at least one intrabony defect of ≥ 3 mm. The surgical procedures included access for debridement using a papilla preservation technique. Defects were filled with DBBM and covered with CB. Clinical evidence after 6 months supported the effectiveness of the combination therapy in the treatment of intrabony defects.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Irokawa
authors.forename: Nobuki
authors.initials: N
authors.lastname: Okubo
authors.forename: Masahiko
authors.initials: M
authors.lastname: Nikaido
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Shimizu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Konobu
authors.forename: Tokuo
authors.initials: T
authors.lastname: Matsui
authors.forename: Takahisa
authors.initials: T
authors.lastname: Fujita
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Goto
authors.forename: Takahiro
authors.initials: T
authors.lastname: Takeuchi
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Ishii
authors.forename: Atsushi
authors.initials: A
authors.lastname: Saito