title: Dengue Chikungunya co-infection: A live-in relationship??
abstract: Dengue and Chikungunya are viral infections that are a major public health hazard in recent times. Both these infections are caused by RNA viruses termed arboviruses owing to their requirement of an arthropod vector to get transmitted to vertebrate hosts. Apart from sharing a common vector, namely Aedes mosquitoes, these infections are also characterized by overlapping clinical presentations and are known to exist as co-infection. The present review traces the history and evolution of co-infection across the globe and provides specific compilation of the scenario in India. Furthermore, clinical manifestations during co-infection are discussed. Lastly, up-to-date information with respect to vector behaviour during co-infection both under laboratory conditions and in natural Aedes populations is reviewed.
authors.affiliation: Vector Borne Disease Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, 110067, India.
authors.forename: Jaspreet
authors.initials: J
authors.lastname: Jain
authors.affiliation: Vector Borne Disease Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, 110067, India.
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Dubey
authors.affiliation: Vector Borne Disease Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, 110067, India.
authors.forename: Jatin
authors.initials: J
authors.lastname: Shrinet
authors.affiliation: Vector Borne Disease Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, 110067, India. Electronic address: sujatha@icgeb.res.in.
authors.forename: Sujatha
authors.initials: S
authors.lastname: Sunil
mesh_terms: D000330:Aedes / Q000821:virology*; D000818:Animals; D065632:Chikungunya Fever / Q000453:epidemiology* / Q000821:virology*; D002646:Chikungunya virus / Q000502:physiology; D060085:Coinfection / Q000453:epidemiology* / Q000821:virology*; D015897:Comorbidity; D003715:Dengue / Q000453:epidemiology* / Q000821:virology*; D003716:Dengue Virus / Q000502:physiology; D004196:Disease Outbreaks / Q000706:statistics & numerical data; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D015995:Prevalence; D012307:Risk Factors
keywords: Aedes; Chikungunya; Clinical studies; Co-infection; Dengue; Evolution