title: MIBG Localization of a Subclinical Paraganglioma of the Bladder.
abstract: Urinary bladder paragangliomas are very rare, and the majority are hormonally active. Nonfunctioning paragangliomas are even rarer and more difficult to diagnose because of absence of catecholamine secretion. We present a 27-year-old woman with an asymptomatic paraganglioma of the urinary bladder discovered incidentally in a patient with prior resection of a functional pararenal paraganglioma. Metabolic profiles and cystoscopy were nondiagnostic. We demonstrate the increased sensitivity of I-MIBG SPECT/CT compared with planar scintigraphy for detection of a nonfunctional paraganglioma of the urinary bladder, which makes it valuable in evaluation of functional and nonfunctional paragangliomas.
authors.affiliation: From the Department of Radiology, University of Virginia Health System, Charlottesville, VA.
authors.forename: Ayman
authors.initials: A
authors.lastname: Mithqal
authors.forename: Pasha
authors.initials: P
authors.lastname: Darvishi
authors.forename: Patrice
authors.initials: P
authors.lastname: Rehm
mesh_terms: D019797:3-Iodobenzylguanidine; D000328:Adult; D005260:Female; D006801:Humans; D010235:Paraganglioma / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D000072098:Single Photon Emission Computed Tomography Computed Tomography; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine