title: Post-stroke epilepsy.
abstract: Post-stroke epilepsy (PSE) is a common complication after stroke, yet treatment options remain limited. While many physicians prescribe antiepileptic drugs (AED) for secondary prevention of PSE, it is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention. This review discusses the current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE.
authors.affiliation: Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan. Electronic address: tanakat@hsp.ncvc.go.jp.
authors.forename: Tomotaka
authors.initials: T
authors.lastname: Tanaka
authors.affiliation: Department of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Ihara
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology / Q000627:therapeutic use; D001812:Blood-Brain Barrier / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D004827:Epilepsy / Q000209:etiology* / Q000378:metabolism / Q000628:therapy*; D006801:Humans; D018836:Inflammation Mediators / Q000037:antagonists & inhibitors / Q000378:metabolism; D012307:Risk Factors; D020521:Stroke / Q000150:complications* / Q000378:metabolism / Q000628:therapy*
chemical_list: D000927:Anticonvulsants; D018836:Inflammation Mediators
keywords: Blood brain barrier; Early seizure; Epileptogenesis; Late seizure; Post stroke epilepsy; Post stroke seizure