title: Copper Catalyzed C-N Cross-Coupling Reaction of Aryl Boronic Acids at Room Temperature through Chelation Assistance.
abstract: A copper-catalyzed selective C-N cross-coupling has been developed based on chelation-assisted amidation of readily available aryl boronic acids at room-temperature under open-flask conditions. The reaction is scalable and tolerates a wide spectrum of functional groups delivering fully substituted unsymmetrical amides in high yields (up to 96%). The C-N cross coupling also established with aryl silanes, extending the palette of coupling partners of this strategy.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Madras , Chennai 600036, Tamil Nadu, India.
authors.forename: Harekrishna
authors.initials: H
authors.lastname: Sahoo
authors.affiliation: Department of Chemistry, Indian Institute of Technology Madras , Chennai 600036, Tamil Nadu, India.
authors.forename: Sayan
authors.initials: S
authors.lastname: Mukherjee
authors.affiliation: Department of Chemistry, Indian Institute of Technology Madras , Chennai 600036, Tamil Nadu, India.
authors.forename: Gowri Sankar
authors.initials: GS
authors.lastname: Grandhi
authors.affiliation: Department of Chemistry, Indian Institute of Technology Madras , Chennai 600036, Tamil Nadu, India.
authors.forename: Jayaraman
authors.initials: J
authors.lastname: Selvakumar
authors.affiliation: Department of Chemistry, Indian Institute of Technology Madras , Chennai 600036, Tamil Nadu, India.
authors.forename: Mahiuddin
authors.identifier: 0000-0001-9415-7137
authors.initials: M
authors.lastname: Baidya