title: [A case of rhinofacial entomophthoromycosis in Soudano-Sahelian tropical climate in Burkina Faso].
abstract: We describe a rhinofacial entomophthoramycosis case in a sexagenarian (65 years old) housewife. She was immunocompetent and resident of Burkina Faso. She consulted both the service of dermatology and the service of stomatology of the Teaching Hospital of Bobo-Dioulasso in February 2016 for a diffuse facial tumefaction evolving over six months. This tumefaction was associated with headaches and a left nasal obstruction. Histological examination of the lesion showed an important and polymorphic inflammatory reaction. Also, a filamentous fungus with wide non-septated hyphae and right-angled fungal branching, consistent with mucormycosis was isolated. Mycological diagnosis based on fungal culture with Sabouraud medium without any antibiotic and cyclohexemide after incubation at 27°C and at 30°C was negative. Furthermore, it was not possible to amplify the DNA extracted from biopsy. Antifungal therapy based on the administration of fluconazole per os at 800mg/day was started allowing clinical improvement. This is the first case of a rhinofacial entomophtharomycosis documented in Bobo-Dioulasso. Rhinofacial entomophthoromycosis is largely unknown, even in tropical regions such as Burkina Faso. This lack of knowledge results in a delay in the diagnosis, and subsequently a bad prognosis. It is therefore urgent to improve knowledge on this disease to guide diagnostic steps, prognosis of outcome, and antifungal therapy.
authors.affiliation: Service de parasitologie-mycologie, département des laboratoires, CHU Sourô Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso. Electronic address: hsanata@yahoo.fr.
authors.forename: S
authors.initials: S
authors.lastname: Bamba
authors.affiliation: Service d'anatomie pathologique, département des laboratoires, CHU Sourô Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso.
authors.forename: V
authors.initials: V
authors.lastname: Konsegré
authors.affiliation: Service de parasitologie-mycologie, CHU Yalgado Ouédraogo, 01 BP 721, Ouagadougou, Burkina Faso.
authors.forename: A
authors.initials: A
authors.lastname: Zida
authors.affiliation: Service de parasitologie-mycologie, département des laboratoires, CHU Sourô Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso.
authors.forename: I
authors.initials: I
authors.lastname: Sangaré
authors.affiliation: Service de parasitologie-mycologie, département des sciences fondamentales et mixtes, université polytechnique de Bobo-Dioulasso, 01 BP 1091, Bobo Dioulasso, Burkina Faso.
authors.forename: M
authors.initials: M
authors.lastname: Cissé
authors.affiliation: Service de stomatologie, département de chirurgie, CHU Sourô Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso.
authors.forename: R
authors.initials: R
authors.lastname: Beogo
authors.affiliation: Service de dermatologie, département de médecine, CHU Sourô Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso.
authors.forename: B
authors.initials: B
authors.lastname: Diallo
authors.affiliation: Service de dermatologie, département de médecine, CHU Sourô Sanou, 01 BP 676, Bobo-Dioulasso, Burkina Faso.
authors.forename: J B
authors.initials: JB
authors.lastname: Andonaba
authors.affiliation: Service de parasitologie-mycologie, département des sciences fondamentales et mixtes, université polytechnique de Bobo-Dioulasso, 01 BP 1091, Bobo Dioulasso, Burkina Faso.
authors.forename: R T
authors.initials: RT
authors.lastname: Guiguemdé
mesh_terms: D000368:Aged; D002050:Burkina Faso; D020092:Conidiobolus / Q000302:isolation & purification / Q000502:physiology; D005148:Facial Dermatoses / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D009091:Mucormycosis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D009667:Nose Deformities, Acquired / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D009668:Nose Diseases / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D014329:Tropical Climate; D020096:Zygomycosis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*
chemical_list: D015725:Fluconazole
keywords: Bobo-Dioulasso; Burkina Faso; Entomophtharomycosis; Entomophthoramycose; Mycose rhinofaciale; Rhinofacial mycosis