title: Location of the narrowest area of the pharynx regarding body mass index and obstructive sleep apnoea severity.
abstract: Among authors studying morphological determinants of the obstructive sleep apnoea (OSA) controversies exist on the location of the narrowest area within the pharynx, critical for development of obstruction. Those disagreements primarily revolve around differences between obese and nonobese OSA patients. Determination whether the location and size of the narrowest area within the pharynx differentiates the obese and nonobese OSA patients.
  
  
  
  A population of 55 subjects was investigated after being diagnosed with OSA in the Polysomnography Laboratory of the Department and Clinic of Otolaryngology in the Medical University of Warsaw, Poland. Additionally a head computed tomography (CT) was performed in all the subjects. The CT images were used to do several crucial measurements which described the geometry of the facial skeleton as well as soft tissues of the head. The obtained results were correlated with apnoea-hypopnoea index (AHI) and body mass index (BMI) values. The data were statistically analysed.
  
  
  
  The distance between the hard palate and posterior pharyngeal wall parallel to the horizontal plane as well as the shortest distance between the soft palate and posterior pharyngeal wall significantly differentiated patients in the subgroups by AHI but not by BMI.
  
  
  
  Pharyngeal obstruction at the level of the hard and soft palate differentiates patients with severe OSA from patients with mild and moderate OSA regardless of BMI.
authors.affiliation: Department of Orthodontics, Warsaw Medical University, Warsaw, Poland, Poland. mkrasny@op.pl.
authors.forename: M
authors.initials: M
authors.lastname: Krasny
authors.forename: J
authors.initials: J
authors.lastname: Wysocki
authors.forename: M
authors.initials: M
authors.lastname: Prus
authors.forename: K
authors.initials: K
authors.lastname: Niemczyk
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010614:Pharynx / Q000473:pathology*; D017286:Polysomnography; D012044:Regression Analysis; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000473:pathology*; D018709:Statistics, Nonparametric
keywords: computed tomography; obstructive sleep apnoea; pharynx