title: A prospective study of breast anthropomorphic measurements, volume and ptosis in 605 Asian patients with breast cancer or benign breast disease.
abstract: OBJECTIVE
  The current study aims to summarize breast anthropomorphic measurement features in Chinese patients with breast diseases and to investigate their potential correlations with demographic factors.
  
  
  METHODS
  Fifteen breast anthropomorphic parameters of 605 Chinese female patients were collected prospectively. Breast ptosis status was scaled by two methods and breast volume was calculated according to a modified formula of BREAST-V.
  
  
  RESULTS
  Among 1210 breasts, the average breast volume was 340.0±109.1 ml (91.8-919.2 ml). The distance from the nipple to the inframammary fold was 7.5±1.6 cm in the standing position. The width of the breast base was 14.3±1.4 cm (8.5-23.5 cm). The incidence of breast ptosis was 22.8% (274/1204), of which 37 (23.5%) and 79 (31.7%) women had severe ptosis assessed by different criteria. Increased height (OR[odds ratio] = 1.500, P<0.001), post-menopausal status (OR = 1.463, P = 0.02), increased BMI, breastfeeding for 7-12 months (OR = 1.882, P = 0.008) and more than one year (OR = 2.367, P = 0.001) were risk factors for an increased breast volume. Post-menopausal status (OR = 2.390, P<0.001 and OR = 2.621, P<0.001 for different scales), BMI≥24.7 kg/m2 (OR = 3.149, P<0.001 and OR = 2.495, P = 0.002), breastfeeding for 7-12 months (OR = 4.136, P = 0.004 and OR = 4.010, P = 0.002), and breastfeeding for more than one year (OR = 6.934, P<0.001 and OR = 6.707, P<0.001) were independent risk factors for breast ptosis.
  
  
  CONCLUSIONS
  The current study provides anthropomorphic measurements data of Chinese women with breast diseases, which are useful for cosmetic and reconstructive breast surgery decisions. Post-menopausal status, increased BMI, and breastfeeding for more than six months were independent risk factors for both increased breast volume and breast ptosis.
authors.affiliation: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.|Department of Oncology, Fudan University, Shanghai Medical College, Fudan University, Shanghai, China.
authors.forename: Nai-Si
authors.initials: NS
authors.lastname: Huang
authors.affiliation: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.|Department of Oncology, Fudan University, Shanghai Medical College, Fudan University, Shanghai, China.
authors.forename: Chen-Lian
authors.initials: CL
authors.lastname: Quan
authors.affiliation: Department of Oncology, Fudan University, Shanghai Medical College, Fudan University, Shanghai, China.|Department of Clinical Statistics, Fudan University Shanghai Cancer Center, Shanghai, China.
authors.forename: Miao
authors.initials: M
authors.lastname: Mo
authors.affiliation: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.|Department of Oncology, Fudan University, Shanghai Medical College, Fudan University, Shanghai, China.
authors.forename: Jia-Jian
authors.initials: JJ
authors.lastname: Chen
authors.affiliation: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.|Department of Oncology, Fudan University, Shanghai Medical College, Fudan University, Shanghai, China.
authors.forename: Ben-Long
authors.initials: BL
authors.lastname: Yang
authors.affiliation: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.|Department of Oncology, Fudan University, Shanghai Medical College, Fudan University, Shanghai, China.
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Huang
authors.affiliation: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.|Department of Oncology, Fudan University, Shanghai Medical College, Fudan University, Shanghai, China.|Collaborative Innovation Center of Cancer Medicine, Shanghai, China.
authors.forename: Jiong
authors.initials: J
authors.lastname: Wu
mesh_terms: D000328:Adult; D000886:Anthropometry / Q000379:methods*; D044466:Asian People; D015992:Body Mass Index; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000208:ethnology / Q000473:pathology*; D001942:Breast Feeding; D001943:Breast Neoplasms / Q000208:ethnology / Q000473:pathology*; D002681:China; D005260:Female; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D015999:Multivariate Analysis; D009929:Organ Size; D017698:Postmenopause; D011446:Prospective Studies; D012307:Risk Factors