title: Spectrophotometric intracutaneous analysis for the assessment of burn wounds: A service evaluation of its clinical application in 50 burn wounds.
abstract: BACKGROUND
  The assessment of burn depth can be challenging even to the experienced burn clinician. Clinical assessment is most widely used to determine burn depth. Because of this subjective nature, various imaging modalities have been invented. The use of photospectometry as a novel technique in burn wound depth analysis has been previously described but the literature is very limited.
  
  
  METHODS
  We carried out a single blinded non-randomized comparative study of healing potential of 50 burn wounds between tissue spectrophotometry analysis versus clinical evaluation.
  
  
  RESULTS
  ScanOSkin™ technology has an overall sensitivity of 75% and specificity of 86% in predicting healing potential of wounds. Analysis of Inter Rater Agreement (IRA) using Kappa calculations showed strengths of agreement varied from fair to moderate in perfusion and burn depth. IRA for assessing pigmentation however, was poor and this was reflected in user feedback.
  
  
  CONCLUSIONS
  There is a potential role for ScanOSkin™ tissue spectrophotometric analysis in burn depth assessment. Future studies comparing several imaging modalities with ScanOSkin®, taking into account costs comparison may be useful for future health resources planning.
authors.affiliation: St Andrew Centre for Plastics and Burns, CM1 7ET, United Kingdom; St Andrews Anglia Ruskin Plastics and Burns Research Unit, Department of Health Sciences, Bishop Hall Lane, CM1 1SQ, United Kingdom. Electronic address: alethea.tan@doctors.org.uk.
authors.forename: A
authors.initials: A
authors.lastname: Tan
authors.affiliation: St Andrew Centre for Plastics and Burns, CM1 7ET, United Kingdom; Scuola di Medicina e Chirurgia, Polo didattico Murri, Via Massarenti 9, 40138 Bologna, Italy.
authors.forename: F A
authors.initials: FA
authors.lastname: Pedrini
authors.affiliation: St Andrew Centre for Plastics and Burns, CM1 7ET, United Kingdom.
authors.forename: G
authors.initials: G
authors.lastname: Oni
authors.affiliation: St Andrew Centre for Plastics and Burns, CM1 7ET, United Kingdom; St Andrews Anglia Ruskin Plastics and Burns Research Unit, Department of Health Sciences, Bishop Hall Lane, CM1 1SQ, United Kingdom.
authors.forename: Q
authors.initials: Q
authors.lastname: Frew
authors.affiliation: St Andrew Centre for Plastics and Burns, CM1 7ET, United Kingdom.
authors.forename: B
authors.initials: B
authors.lastname: Philp
authors.affiliation: St Andrew Centre for Plastics and Burns, CM1 7ET, United Kingdom.
authors.forename: D
authors.initials: D
authors.lastname: Barnes
authors.affiliation: St Andrew Centre for Plastics and Burns, CM1 7ET, United Kingdom.
authors.forename: P
authors.initials: P
authors.lastname: Dziewulski
mesh_terms: D001830:Body Surface Area; D002056:Burns / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D012867:Skin; D013053:Spectrophotometry; D013997:Time Factors; D015599:Trauma Severity Indices; D014945:Wound Healing; D055815:Young Adult
keywords: Clinical applicability; Healing potential burn wounds; Spectrophotometric intracutaneous analysis