title: The Comparison of Hydrochloric Acid and Phosphoric Acid Treatments in the Preparation of Montmorillonite Catalysts for RNA Synthesis.
abstract: The treatment of clay minerals with a preliminary acid wash and titration to pH 7 has proven to generate catalysts for the most interesting of oligomerization reactions in which activated RNA-nucleotides generate oligomers up to 40-mers. Significantly, not all clay minerals become catalytic following this treatment and none are catalytic in the absence of such treatment. The washing procedure has been modified and explored further using phosphoric acid and the outcomes are compared to those obtained when clay samples are prepared following a hydrochloric acid wash.
authors.affiliation: Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA. alderm@rpi.edu.
authors.forename: Michael Frank
authors.initials: MF
authors.lastname: Aldersley
authors.affiliation: Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
authors.forename: Prakash C
authors.initials: PC
authors.lastname: Joshi
authors.affiliation: Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
authors.forename: Yixing
authors.initials: Y
authors.lastname: Huang
mesh_terms: D001546:Bentonite / Q000737:chemistry*; D002384:Catalysis; D006851:Hydrochloric Acid / Q000737:chemistry*; D010756:Phosphoric Acids / Q000737:chemistry*; D012313:RNA / Q000138:chemical synthesis*
chemical_list: D010756:Phosphoric Acids; D001546:Bentonite; D012313:RNA; C030242:phosphoric acid; D006851:Hydrochloric Acid
keywords: Activated nucleotides; Montmorillonite; Oligonucleotides