title: Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis.
abstract: In this paper, a porous polymer nanostructure has been integrated with droplet-based microfluidics in a single planar format. Monolithic porous polymer (MPP) was formed selectively within a microfluidic channel. The resulting analyte bands were sequentially comartmentalised into droplets. This device reduces band broadening and the effects of post-column dead volume by the combination of the two techniques. Moreover it offers the precise control of nano/picoliter volume samples.
authors.affiliation: Department of Biosystems Science and Engineering, Bioegineering Laboratory, ETH Zurich, CH-4058 Basel, Switzerland.
authors.forename: Jin-Young
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Department of Biochemistry, Chungbuk National University, Cheongju, Chungbuk 361-763 Korea.
authors.forename: Soo-Ik
authors.initials: SI
authors.lastname: Chang
authors.affiliation: Institute of Chemical and Bioengineering, Department of Chemistry and Applied Bioscience, ETH Zurich, CH-8093 Zurich, Switzerland.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: deMello
authors.affiliation: Department of Bioengineering, Imperial College London, London, SW7 2AZ UK.
authors.forename: Danny
authors.initials: D
authors.lastname: O'Hare