title: Brief Report: Longitudinal Opioid Use Among HIV-Infected Patients, 2000 to 2014.
abstract: Longitudinal opioid prescription use is unknown among HIV-infected patients. Group-based trajectory modeling followed by multinomial logistic regression was used to identify distinct trajectories and their association with baseline characteristics among 1239 HIV-infected UNC CFAR HIV Clinical Cohort participants, 2000-2014. Three trajectories were identified: (1) 72% never/sporadic opioid use (referent group), (2) 11% episodic use (associated with female sex, depression, drug-related diagnoses, antiretroviral therapy use, and undetectable HIV RNA), and (3) 16% chronic use (associated with older age, female sex, and mental health diagnoses). Overall, opioid prescription decreased substantially with longer time in HIV care among both episodic and chronic users.
authors.affiliation: *Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; and †Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
authors.forename: Laurence
authors.initials: L
authors.lastname: Brunet
authors.forename: Sonia
authors.initials: S
authors.lastname: Napravnik
authors.forename: Amy D
authors.initials: AD
authors.lastname: Heine
authors.forename: Peter A
authors.initials: PA
authors.lastname: Leone
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Eron
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D019966:Substance-Related Disorders / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D000701:Analgesics, Opioid