title: Autoimmune neuropathies associated to rheumatic diseases.
abstract: Systemic manifestations are frequent in autoimmune rheumatic diseases and include peripheral nervous system damage. Neuron cell body, axons and myelin sheath may all be affected in this context. This involvement results in severe and sometimes disabling symptoms. Sensory, motor and autonomic features may be present in different patterns that emerge as peculiar clinical pictures. Prompt recognition of these neuropathies is pivotal to guide treatment and reduce the risks of long term disability. In this review, we aim to describe the main immune-mediated neuropathies associated to rheumatic diseases: sensory neuronopathies, multiple mononeuropathies and chronic inflammatory demyelinating polyradiculoneuropathy, with an emphasis on clinical features and therapeutic options.
authors.affiliation: Department of Neurology-Faculty of Medical Science-State University of Campinas, Brazil.
authors.forename: Alberto R M
authors.initials: AR
authors.lastname: Martinez
authors.affiliation: Department of Neurology-Faculty of Medical Science-State University of Campinas, Brazil.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Faber
authors.affiliation: Department of Neurology-Faculty of Medical Science-State University of Campinas, Brazil.
authors.forename: Anamarli
authors.initials: A
authors.lastname: Nucci
authors.affiliation: Rheumatology Division-Department of Medicine--Faculty of Medical Science-State University of Campinas, Brazil; Autoimmunity Disease Laboratory-State University of Campinas, Brazil. Electronic address: appenzellersimone@yahoo.com.
authors.forename: Simone
authors.initials: S
authors.lastname: Appenzeller
authors.affiliation: Department of Neurology-Faculty of Medical Science-State University of Campinas, Brazil. Electronic address: mcfrancajr@uol.com.br.
authors.forename: Marcondes C
authors.initials: MC
authors.lastname: França
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D020422:Mononeuropathies / Q000209:etiology* / Q000276:immunology; D010523:Peripheral Nervous System Diseases / Q000209:etiology* / Q000276:immunology; D012216:Rheumatic Diseases / Q000150:complications*
keywords: Autoimmune neuropathies; Rheumatic diseases