title: Myocardial perfusion imaging with PET.
abstract: Noninvasive assessment of coronary artery disease remains a challenging task, with a large armamentarium of diagnostic modalities. Myocardial perfusion imaging (MPI) is widely used for this purpose whereby cardiac positron emission tomography (PET) is considered the gold standard. Next to relative radiotracer distribution, PET allows for measurement of absolute myocardial blood flow. This quantification of perfusion improves diagnostic accuracy and prognostic value. Cardiac hybrid imaging relies on the fusion of anatomical and functional imaging using coronary computed tomography angiography and MPI, respectively, and provides incremental value as compared with either stand-alone modality.
authors.affiliation: Department of Cardiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
authors.forename: Roel S
authors.initials: RS
authors.lastname: Driessen
authors.affiliation: Department of Nuclear Medicine and Radiology, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: Pieter G
authors.initials: PG
authors.lastname: Raijmakers
authors.affiliation: Department of Cardiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
authors.forename: Wijnand J
authors.initials: WJ
authors.lastname: Stuijfzand
authors.affiliation: Department of Cardiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. p.knaapen@vumc.nl.
authors.forename: Paul
authors.initials: P
authors.lastname: Knaapen
mesh_terms: D001783:Blood Flow Velocity; D000072226:Computed Tomography Angiography; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000503:physiopathology; D053805:Fractional Flow Reserve, Myocardial; D006801:Humans; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D000072078:Positron Emission Tomography Computed Tomography; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D011379:Prognosis; D019275:Radiopharmaceuticals / Q000008:administration & dosage; D015203:Reproducibility of Results; D012720:Severity of Illness Index
chemical_list: D019275:Radiopharmaceuticals
keywords: Myocardial blood flow; Myocardial perfusion imaging; Positron emission tomography