title: LASER server: ancestry tracing with genotypes or sequence reads.
abstract: CONCLUSIONS
  To enable direct comparison of ancestry background in different studies, we developed LASER to estimate individual ancestry by placing either sezquenced or genotyped samples in a common ancestry space, regardless of the sequencing strategy or genotyping array used to characterize each sample. Here we describe the LASER server to facilitate application of the method to a wide range of genetic studies. The server provides genetic ancestry estimation for different geographic regions and user-friendly interactive visualization of the results.
  
  
  METHODS
  The LASER server is freely accessible at http://laser.sph.umich.edu/.
  
  
  BACKGROUND
  dtaliun@umich.edu or wangcl@gis.a-star.edu.sg.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Taliun
authors.affiliation: Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore.
authors.forename: Sonia P
authors.initials: SP
authors.lastname: Chothani
authors.affiliation: Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck 6020, Austria.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schönherr
authors.affiliation: Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck 6020, Austria.
authors.forename: Lukas
authors.initials: L
authors.lastname: Forer
authors.affiliation: Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Boehnke
authors.affiliation: Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.
authors.forename: Gonçalo R
authors.initials: GR
authors.lastname: Abecasis
authors.affiliation: Computational and Systems Biology, Genome Institute of Singapore, Singapore 138672, Singapore.
authors.forename: Chaolong
authors.initials: C
authors.lastname: Wang
mesh_terms: D014644:Genetic Variation; D006801:Humans; D058974:Phylogeography / Q000379:methods*; D044382:Population Groups / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software