title: Transcription Factors as a Target for Vaccination Against Ticks and Mites.
abstract: Ticks and mites are well-known ectoparasites as potential vectors for numerous bacteria, viruses, and parasites. Many being blood feeders add to physiological deterioration, morbidity, and mortality of their vertebrate hosts. To control them, transcription factors have been identified and studied in their role to sustain such arthropod pests. This paper summarizes some of the work done on those factors involved during blood feeding, reproduction, or when interacting with their pathogens and symbiont populations. Any transcription factor supporting the equilibrium developed by the ticks/mites could become a potential target for new control methods to prevent some of their key physiological functions.
authors.affiliation: Coventry University, Coventry, United Kingdom. Electronic address: olivier.sparagano@coventry.ac.uk.
authors.forename: O A E
authors.initials: OA
authors.lastname: Sparagano
mesh_terms: D000818:Animals; D008925:Mites / Q000382:microbiology / Q000469:parasitology; D013559:Symbiosis; D013987:Ticks / Q000382:microbiology / Q000469:parasitology; D014157:Transcription Factors / Q000187:drug effects*; D014612:Vaccines / Q000008:administration & dosage*
chemical_list: D014157:Transcription Factors; D014612:Vaccines
keywords: Antigen targets; Mites; Ticks; Transcription factors; Vaccine development