title: Scabies in a bilateral hand allograft recipient: An additional mimicker of acute skin rejection in vascularized composite allotransplantation.
abstract: Vascularized composite tissue allografts include skin, which frequently undergoes, in the early post-graft period, acute rejections. The diagnosis of acute rejection may be difficult as it can be mimicked by several dermatoses. We present a bilateral hand allograft recipient who developed, 16.5 years post-graft, cutaneous lesions raising suspicion about rejection. Physical examination and skin biopsy were diagnostic of scabies. This ectoparasitosis should be added in the list of dermatoses that can mimic allograft rejection in vascular composite allografts.
authors.affiliation: Department of Dermatology, Edouard Herriot Hospital Group, Lyon, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Kanitakis
authors.affiliation: Department of Nephrology, Edouard Herriot Hospital Group, Lyon, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Morelon
mesh_terms: D064591:Allografts / Q000469:parasitology / Q000473:pathology; D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D006084:Graft Rejection / Q000175:diagnosis* / Q000473:pathology / Q000517:prevention & control; D063987:Hand Transplantation / Q000009:adverse effects*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects* / Q000379:methods; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007559:Ivermectin / Q000627:therapeutic use; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D012520:Sarcoptes scabiei; D012532:Scabies / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology; D012867:Skin / Q000469:parasitology / Q000473:pathology; D014184:Transplantation, Homologous / Q000009:adverse effects; D063986:Vascularized Composite Allotransplantation / Q000009:adverse effects*
chemical_list: D000977:Antiparasitic Agents; D007166:Immunosuppressive Agents; D007559:Ivermectin
keywords: 
  Sarcoptes scabiei
  ; acute rejection; hand allografts; scabies; skin; vascularized composite allografts