title: Confining a bi-enzyme inside the nanochannels of a porous aluminum oxide membrane for accelerating the enzymatic reactions.
abstract: An artificial metabolon with high conversion efficiency was constructed by confining a bi-enzyme into porous aluminum oxide nanochannels, which accelerated enzymatic reactions by minimizing the diffusion loss of intermediate species.
authors.affiliation: Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China. liusq@seu.edu.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Shangguan
authors.affiliation: Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China. liusq@seu.edu.cn.
authors.forename: Yuanqing
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China. liusq@seu.edu.cn.
authors.forename: Xu
authors.initials: X
authors.lastname: Liu
authors.affiliation: Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China. liusq@seu.edu.cn.
authors.forename: Jiachao
authors.initials: J
authors.lastname: Yu
authors.affiliation: Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China. liusq@seu.edu.cn.
authors.forename: Songqin
authors.initials: S
authors.lastname: Liu
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry* / Q000378:metabolism; D019363:Cytochrome P-450 CYP1A1 / Q000737:chemistry / Q000378:metabolism*; D004058:Diffusion; D005954:Glucosephosphate Dehydrogenase / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D036103:Nanotechnology / Q000295:instrumentation*; D010316:Particle Size; D016062:Porosity; D013499:Surface Properties
chemical_list: D005954:Glucosephosphate Dehydrogenase; D019363:Cytochrome P-450 CYP1A1; D000537:Aluminum Oxide