title: Study of Aortic Valve Sclerosis as A Marker of Atherosclerosis in Acute Coronary Syndromes.
abstract: BACKGROUND
  Aortic valve sclerosis has been shown to be associated with increased incidence, chances of developing myocardial infarction and even death. The epidemiological risk factors causing calcification of aortic valves have also been found to cause atherosclerosis.
  
  
  OBJECTIVE
  To analyse the epidemiological risk factors causing aortic valve sclerosis which have been studied in details and analysed to see whether they cause any significant increase in the incidence of cardiovascular events.
  
  
  METHODS
  This prospective case-control study was conducted between 1stJan 2015 to 31stDec 2015 in NEIGRIHMS hospital and data for age, gender, socioeconomic status, hypertension, diabetes, tobacco use, Body Mass Iindex (BMI), cholesterol levels, Electrocardiography (ECG) changes and Ejection Fraction (EF) were collected and analysed by using SPSS software version 22.
  
  
  RESULTS
  Hypertension, diabetes, weight, BMI, hyperglycaemia and hyperlipidemia were not found to be significantly associated with aortic valve sclerosis in patients presenting with acute coronary syndromes. The presence of aortic valve sclerosis was also not associated with increased risk of cardiovascular mortality and morbidity.
  
  
  CONCLUSIONS
  The risk factors for atherosclerosis were found to be associated with the presence of aortic valve sclerosis more in the control group and hence finding of a sclerosed aortic valve in the apparent normal population might identify those persons at increased risk of developing coronary artery disease and appropriate preventive measures should be taken before the disease sets in.
authors.affiliation: Resident Doctor, Department of Medicine, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Preeti Jane
authors.initials: PJ
authors.lastname: Picardo
authors.affiliation: Resident Doctor, Department of Surgery, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Peter Daniel S
authors.initials: PD
authors.lastname: Khariong
authors.affiliation: Associate Professor, Department of Surgery, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Ranendra
authors.initials: R
authors.lastname: Hajong
authors.affiliation: Resident Doctor, Department of Surgery, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Debobratta
authors.initials: D
authors.lastname: Hajong
authors.affiliation: Resident Doctor, Department of Surgery, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Narang
authors.initials: N
authors.lastname: Naku
authors.affiliation: Resident Doctor, Department of Surgery, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Madhur
authors.initials: M
authors.lastname: Anand
authors.affiliation: Resident Doctor, Department of Surgery, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Girish
authors.initials: G
authors.lastname: Sharma
authors.affiliation: Resident Doctor, Department of Surgery, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: K Lenish
authors.initials: KL
authors.lastname: Singh
keywords: Coronary artery disease; Coronary events; Epidemiological risk