title: Splenic histiocyte-rich pseudotumor following chemotherapy for non Hodgkin diffuse large B cell lymphoma.
abstract: Chemotherapy may induce mass lesion in rare conditions, which can be easily mistaken as a residual tumor mass. In this report, we describe a mass affecting spleen in a patient received chemotherapy for non Hodgkin diffuse large B cell lymphoma. This mass proved histologically to be non neoplastic formed of sheets of histiocytes and xanthoma cells, which is called histiocyte-rich pseudotumor. This report describes this rare lesion and the possible differential diagnosis.
authors.affiliation: Pathology Department, Faculty of Medicine, Menofiya University, Shebein Elkom, Egypt.
authors.forename: A G
authors.initials: AG
authors.lastname: Abdou
authors.affiliation: Pathology Department, Faculty of Medicine, Menofiya University, Shebein Elkom, Egypt.
authors.forename: M
authors.initials: M
authors.lastname: Kandil
authors.affiliation: Pathology Department, Faculty of Medicine, Menofiya University, Shebein Elkom, Egypt.
authors.forename: M S
authors.initials: MS
authors.lastname: Eldien
authors.affiliation: Pathology Department, Faculty of Medicine, Menofiya University, Shebein Elkom, Egypt.
authors.forename: R
authors.initials: R
authors.lastname: Abdallah
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D006644:Histiocytes / Q000737:chemistry / Q000187:drug effects* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013154:Spleen / Q000737:chemistry / Q000187:drug effects* / Q000473:pathology; D013158:Splenic Diseases / Q000139:chemically induced* / Q000473:pathology; D016896:Treatment Outcome; D014973:Xanthomatosis / Q000139:chemically induced* / Q000473:pathology
chemical_list: D015415:Biomarkers
keywords: Postchemotherapy; Spleen; Xanthomatous pseudotumor