title: Adenoid bacterial colonization in a paediatric population.
abstract: Adenoids play a key role in both respiratory and ear infection in children. It has also been shown that adenoidectomy improves these symptoms in this population. The main goal of the present study was to evaluate adenoid bacterial colonization and document a possible relation with infectious respiratory disease. A prospective observational study was designed to evaluate the proposed hypothesis in a paediatric population submitted to adenoidectomy by either infectious or non-infectious indications and compare these two cohorts. A total of 62 patients with ages ranging from 1 to 12 years old were enrolled in the study. Adenoid surface, adenoid core and middle meatus microbiota were compared. A close association between adenoid colonization and nasal infection was found, supporting that adenoids may function as bacterial reservoir for upper airway infection. The obtained results also contribute to explain the success of adenoidectomy in patients with infectious indications.
authors.affiliation: Serviço de otorrinolaringologia (ORL), Hospital de Beatriz Ângelo (HBA), Avenida Carlos Teixeira 3, 2674-514, Loures, Portugal.
authors.forename: João
authors.initials: J
authors.lastname: Subtil
authors.affiliation: Departamento de Doenças Infeciosas (DDI), Instituto Nacional de Saúde Dr. Ricardo Jorge (INSA), Avenida Padre Cruz, 1649-016, Lisbon, Portugal.
authors.forename: João Carlos
authors.initials: JC
authors.lastname: Rodrigues
authors.affiliation: Departamento de Doenças Infeciosas (DDI), Instituto Nacional de Saúde Dr. Ricardo Jorge (INSA), Avenida Padre Cruz, 1649-016, Lisbon, Portugal.
authors.forename: Lúcia
authors.initials: L
authors.lastname: Reis
authors.affiliation: Serviço de otorrinolaringologia (ORL), Hospital de Beatriz Ângelo (HBA), Avenida Carlos Teixeira 3, 2674-514, Loures, Portugal.
authors.forename: Luís
authors.initials: L
authors.lastname: Freitas
authors.affiliation: Serviço de otorrinolaringologia (ORL), Hospital de Beatriz Ângelo (HBA), Avenida Carlos Teixeira 3, 2674-514, Loures, Portugal.
authors.forename: Joana
authors.initials: J
authors.lastname: Filipe
authors.affiliation: Serviço de otorrinolaringologia (ORL), Hospital de Beatriz Ângelo (HBA), Avenida Carlos Teixeira 3, 2674-514, Loures, Portugal.
authors.forename: Alberto
authors.initials: A
authors.lastname: Santos
authors.affiliation: Serviço de otorrinolaringologia (ORL), Hospital de Beatriz Ângelo (HBA), Avenida Carlos Teixeira 3, 2674-514, Loures, Portugal.
authors.forename: Carlos
authors.initials: C
authors.lastname: Macor
authors.affiliation: Departamento de Microbiologia e Imunologia, Faculdade de Farmácia da Universidade de Lisboa, Av Prof Gama Pinto, 1649-003, Lisbon, Portugal.
authors.forename: Aida
authors.initials: A
authors.lastname: Duarte
authors.affiliation: Departamento de Saúde Ambiental, Unidade de Investigação e Desenvolvimento, INSA, Avenida Padre Cruz, 1649-016, Lisbon, Portugal. maria.jordao@insa.min-saude.pt.
authors.forename: Luisa
authors.identifier: http://orcid.org/0000-0002-5608-021X
authors.initials: L
authors.lastname: Jordao
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000382:microbiology* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000382:microbiology* / Q000517:prevention & control
keywords: Adenoidectomy; Children; Nasal and adenoidal microbiota; Upper airways infection