title: [Analysis of genetic polymorphisms of 15 STR loci among ethnic Hans from Xiamen].
abstract: OBJECTIVE
  To assess the value of 15 short tandem repeat (STR) loci selected by an AmpFLSTR IdentifilerTMsystem for personal identification and paternity testing among ethnic Hans from Xiamen, Fujian.
  
  
  METHODS
  For 400 unrelated individuals, allelic frequencies for the 15 STR loci from the AmpFLSTR IdentifilerTMkit were determined. Population genetics parameters for forensic usage were calculated.
  
  
  RESULTS
  No deviation of the observed allele frequency from Hardy-Weinberg equilibrium expectations was found by Chi-square test (P>0.05). All of the 15 loci were highly polymorphic. Observed heterozygosity has varied between 0.580 and 0.868. Matching probability was between 0.036 and 0.148. Power of discrimination was between 0.798 and 0.967. Polymorphic information content was between 0.560 and 0.850. And power of exclusion was between 0.268 and 0.730.
  
  
  CONCLUSIONS
  All of the 15 loci selected by the AmpFLSTR IdentifilerTMsystem are highly polymorphic among ethnic Hans from Xiamen. By determining the alleles and allelic frequencies, data for genetic polymorphisms usable for paternity testing and personal identification for local population were obtained.
authors.affiliation: The First Clinical Medical School, Fujian Medical University, Fuzhou, Fujian 350108, China. songxyxm@126.com.
authors.forename: Lili
authors.initials: L
authors.lastname: Wu
authors.forename: Peng
authors.initials: P
authors.lastname: Ran
authors.forename: Xiujuan
authors.initials: X
authors.lastname: Zheng
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Zhou
authors.forename: Bin
authors.initials: B
authors.lastname: Pei
authors.forename: Xiuyu
authors.initials: X
authors.lastname: Song
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics; D016009:Chi-Square Distribution; D002681:China; D053803:Forensic Genetics / Q000379:methods*; D005787:Gene Frequency; D005828:Genetics, Population / Q000379:methods*; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D018895:Microsatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic