title: Validation of cadmium-zinc-telluride camera for measurement of left ventricular systolic performance.
abstract: There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging.
  
  
  
  60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement.
  
  
  
  48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques.
  
  
  
  CZT-SPECT is reliable for LVEF measurement.
authors.affiliation: Department of Cardiology, CHU Gabriel Montpied, Clermont-Ferrand, France. ecoupez@chu-clermontferrand.fr.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Coupez
authors.affiliation: Nuclear Medicine Department, Jean Perrin Cancer Center, Clermont-Ferrand, France.
authors.forename: Charles
authors.initials: C
authors.lastname: Merlin
authors.affiliation: ISIT, UMR CNRS 6284, Université d'Auvergne Clermont1, Clermont-Ferrand, France.
authors.forename: Viateur
authors.initials: V
authors.lastname: Tuyisenge
authors.affiliation: ISIT, UMR CNRS 6284, Université d'Auvergne Clermont1, Clermont-Ferrand, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Sarry
authors.affiliation: DRCI, CHU Gabriel Montpied, Clermont-Ferrand, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Pereira
authors.affiliation: Department of Cardiology, CHU Gabriel Montpied, Clermont-Ferrand, France.
authors.forename: Jean René
authors.initials: JR
authors.lastname: Lusson
authors.affiliation: Department of Radiology, CHU Gabriel Montpied, Clermont-Ferrand, France.
authors.forename: Louis
authors.initials: L
authors.lastname: Boyer
authors.affiliation: Department of Radiology, CHU Gabriel Montpied, Clermont-Ferrand, France.
authors.forename: Lucie
authors.initials: L
authors.lastname: Cassagnes
mesh_terms: D002104:Cadmium; D004452:Echocardiography; D015902:Gamma Cameras; D006801:Humans; D008279:Magnetic Resonance Imaging; D055414:Myocardial Perfusion Imaging; D015203:Reproducibility of Results; D000072657:ST Elevation Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012680:Sensitivity and Specificity; D013691:Tellurium; D015899:Tomography, Emission-Computed, Single-Photon; D016277:Ventricular Function, Left / Q000502:physiology*; D015032:Zinc
chemical_list: C474490:CdZnTe; D002104:Cadmium; D015032:Zinc; D013691:Tellurium
keywords: Echocardiography; SPECT; left ventricular function; magnetic resonance imaging; myocardial infarction; myocardial perfusion imaging