title: Emotion Perception Mediates the Predictive Relationship Between Verbal Ability and Functional Outcome in High-Functioning Adults with Autism Spectrum Disorder.
abstract: The aim of this study was to identify specific cognitive abilities that predict functional outcome in high-functioning adults with autism spectrum disorder (ASD), and to clarify the contribution of those abilities and their relationships. In total, 41 adults with ASD performed cognitive tasks in a broad range of neuro- and social cognitive domains, and information concerning functional outcomes was obtained. Regression analyses revealed that emotion perception and verbal generativity predicted adaptive functioning directly, and the former mediated between the other two. These findings provide the first evidence of a triadic relationship among neuro- and social cognition and functional outcome in this population. Our results suggest that psychosocial interventions targeting these cognitive abilities could benefit social adaptation in adults with ASD.
authors.affiliation: Faculty of Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. o2ka.psycho@gmail.com.|The Organization for Promoting Neurodevelopmental Disorder Research (OPNDR), 40 Shogoin Sanno-cho, Sakyo-ku, Kyoto, 606-8392, Japan. o2ka.psycho@gmail.com.
authors.forename: Sadao
authors.identifier: 0000-0001-6282-840X
authors.initials: S
authors.lastname: Otsuka
authors.affiliation: Department of Neurodevelopmental Psychiatry, Habilitation and Rehabilitation, Faculty of Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Shota
authors.initials: S
authors.lastname: Uono
authors.affiliation: Department of Neurodevelopmental Psychiatry, Habilitation and Rehabilitation, Faculty of Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
authors.forename: Sayaka
authors.initials: S
authors.lastname: Yoshimura
authors.affiliation: Faculty of Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.|International Research Fellow of the Japan Society for the Promotion of Science (JSPS), 5-3-1, Kojimachi, Chiyoda-ku, 102-0083, Tokyo, Japan.
authors.forename: Shuo
authors.initials: S
authors.lastname: Zhao
authors.affiliation: Faculty of Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.|The Organization for Promoting Neurodevelopmental Disorder Research (OPNDR), 40 Shogoin Sanno-cho, Sakyo-ku, Kyoto, 606-8392, Japan.
authors.forename: Motomi
authors.initials: M
authors.lastname: Toichi
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000067877:Autism Spectrum Disorder / Q000523:psychology*; D004644:Emotions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014705:Verbal Behavior; D055815:Young Adult
keywords: Adaptive behavior; Autism spectrum disorder (ASD); Emotion recognition; Predictor; Social cognition; Social functioning