title: [Five-year survival analysis in patients with penile cancer].
abstract: BACKGROUND
  Short-term survival of penile cancer is poor. The objective was to describe the 5-years penile cancer survival.
  
  
  METHODS
  Retrospective cohort study. We included patients with penile cancer managed surgically from 2010 to 2014. Descriptive statistics were used for socio-demographic variables and the Kaplan-Meier estimator for survival function.
  
  
  RESULTS
  We studied 22 patients with a mean age of 64.95 years and a time of evolution of 25 months after the diagnosis. 68.2% of patients smoked or had human papillomavirus (HPV); they all presented phimosis; 72.7% had pain in the penis and the groin area; 81.8% had palpable lymph nodes and 45.5% lesions ≥ 3 cm; 86.3% were diagnosed in clinical stage IIIa. 59.1% underwent partial penectomy and 86.4% had squamous cell variety. 40.9% of patients died six months after the surgery. 66% of the smokers presented metastasis; all of the patients that smoked and had HPV infection had neurovascular invasion and died; 83.3% of the patients (n = 6) who underwent partial penectomy and positive lymph node dissection due to metastases died. The 5-years mortality of patients with penile cancer was 40.9%.
  
  
  CONCLUSIONS
  Tobacco use and HPV increase morbidity and mortality in patients with penile cancer; lesions greater than 5 cm are more common in smokers. The size of the lesion increases with the delay in treatment.
authors.affiliation: División de Investigación en Salud, Hospital de Traumatología y Ortopedia, Centro Médico Nacional "Manuel Ávila Camacho", Instituto Mexicano del Seguro Social, Puebla, Puebla, México. dralmoja@hotmail.com.
authors.forename: Álvaro José
authors.initials: ÁJ
authors.lastname: Montiel-Jarquín
authors.forename: Antonio Jesús
authors.initials: AJ
authors.lastname: Contreras-Díaz
authors.forename: Eduardo
authors.initials: E
authors.lastname: Vázquez-Cruz
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: Chopin-Gazga
authors.forename: María Socorro
authors.initials: MS
authors.lastname: Romero-Figueroa
authors.forename: Ivet
authors.initials: I
authors.lastname: Etchegaray-Morales
authors.forename: Ivan
authors.initials: I
authors.lastname: Alvarado-Ortega
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D010412:Penile Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis
keywords: Epidemiology; Mortality; Penile cancer; Survival