title: Chicken Meat as a Reservoir of Colistin-Resistant Escherichia coli Strains Carryingmcr-1Genes in South America.
abstract: The detection and rapid spread of colistin-resistantEnterobacteriaceaecarrying themcr-1gene has created an urgent need to strengthen surveillance. In this study, eight clonally unrelated colistin-resistantEscherichia coliisolates carryingmcr-1andblaCTX-MorblaCMY-2genes were isolated from commercial chicken meat in Brazil. MostE. colistrains carried IncX4 plasmids, previously identified in human and animal isolates. These results highlight a new reservoir ofmcr-1-harboringE. colistrains in South America.
authors.affiliation: Department of Food and Experimental Nutrition, School of Pharmacy, University of São Paulo, São Paulo, Brazil.|Food Research Center, University of São Paulo, São Paulo, Brazil.
authors.forename: Daniel Farias
authors.initials: DF
authors.lastname: Monte
authors.affiliation: Department of Veterinary Medicine, Federal University of Paraná, Paraná, Brazil.
authors.forename: Andressa
authors.initials: A
authors.lastname: Mem
authors.affiliation: Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil.
authors.forename: Miriam R
authors.initials: MR
authors.lastname: Fernandes
authors.affiliation: Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil.
authors.forename: Louise
authors.initials: L
authors.lastname: Cerdeira
authors.affiliation: Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Esposito
authors.affiliation: Department of Veterinary Medicine, Federal University of Paraná, Paraná, Brazil.
authors.forename: Julia A
authors.initials: JA
authors.lastname: Galvão
authors.affiliation: Department of Food and Experimental Nutrition, School of Pharmacy, University of São Paulo, São Paulo, Brazil.|Food Research Center, University of São Paulo, São Paulo, Brazil.
authors.forename: Bernadette D G M
authors.initials: BDGM
authors.lastname: Franco
authors.affiliation: Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil lincopan@usp.br.|Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
authors.forename: Nilton
authors.identifier: 0000-0003-0161-5800
authors.initials: N
authors.lastname: Lincopan
authors.affiliation: Department of Food and Experimental Nutrition, School of Pharmacy, University of São Paulo, São Paulo, Brazil.|Food Research Center, University of São Paulo, São Paulo, Brazil.
authors.forename: Mariza
authors.initials: M
authors.lastname: Landgraf
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D002645:Chickens / Q000382:microbiology*; D003091:Colistin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000188:drug therapy; D029968:Escherichia coli Proteins / Q000235:genetics*; D005517:Foodborne Diseases / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control; D006801:Humans; D008461:Meat Products / Q000382:microbiology*; D010957:Plasmids / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; C000614037:MCR-1 protein, E coli; C103022:beta-lactamase CMY-2; D001618:beta-Lactamases; C000602253:beta-lactamase CTX-M, E coli; D003091:Colistin
keywords: Brazil; CTX-M-8; ESBL; IncX4; mcr-1; polymyxins