title: Genomic prediction for beef fatty acid profile in Nellore cattle.
abstract: The objective of this study was to compare SNP-BLUP, BayesCπ, BayesC and Bayesian Lasso methodologies to predict the direct genomic value for saturated, monounsaturated, and polyunsaturated fatty acid profile, omega 3 and 6 in the Longissimus thoracis muscle of Nellore cattle finished in feedlot. A total of 963 Nellore bulls with phenotype for fatty acid profiles, were genotyped using the Illumina BovineHD BeadChip (Illumina, San Diego, CA) with 777,962 SNP. The predictive ability was evaluated using cross validation. To compare the methodologies, the correlation between DGV and pseudo-phenotypes was calculated. The accuracy varied from -0.40 to 0.62. Our results indicate that none of the methods excelled in terms of accuracy, however, the SNP-BLUP method allows obtaining less biased genomic evaluations, thereby; this method is more feasible when taking into account the analyses' operating cost. Despite the lowest bias observed for EBV, the adjusted phenotype is the preferred pseudophenotype considering the genomic prediction accuracies regarding the context of the present study.
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil. Electronic address: chiaia1@yahoo.com.br.
authors.forename: Hermenegildo Lucas Justino
authors.initials: HLJ
authors.lastname: Chiaia
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Elisa
authors.initials: E
authors.lastname: Peripoli
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Rafael Medeiros de Oliveira
authors.initials: RMO
authors.lastname: Silva
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Carolyn
authors.initials: C
authors.lastname: Aboujaoude
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Fabiele Loise Braga
authors.initials: FLB
authors.lastname: Feitosa
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Marcos Vinicius Antunes de
authors.initials: MVA
authors.lastname: Lemos
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Mariana Piatto
authors.initials: MP
authors.lastname: Berton
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Bianca Ferreira
authors.initials: BF
authors.lastname: Olivieri
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Rafael
authors.initials: R
authors.lastname: Espigolan
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Rafael Lara
authors.initials: RL
authors.lastname: Tonussi
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Daniel Gustavo Mansan
authors.initials: DGM
authors.lastname: Gordo
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Tiago
authors.initials: T
authors.lastname: Bresolin
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Ana Fabrícia Braga
authors.initials: AFB
authors.lastname: Magalhães
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Gerardo Alves Fernandes
authors.initials: GAF
authors.lastname: Júnior
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Lúcia Galvão de
authors.initials: LG
authors.lastname: Albuquerque
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Henrique Nunes de
authors.initials: HN
authors.lastname: Oliveira
authors.affiliation: Faculdade de Medicina Veterinária e Zootecnia, USP, Pirassununga, SP, 13635-900, Brazil.
authors.forename: Joyce de Jesus Mangini
authors.initials: JJM
authors.lastname: Furlan
authors.affiliation: Faculdade de Medicina Veterinária e Zootecnia, USP, Pirassununga, SP, 13635-900, Brazil.
authors.forename: Adrielle Mathias
authors.initials: AM
authors.lastname: Ferrinho
authors.affiliation: Faculdade de Zootecnia e Engenharia de Alimentos, USP, Pirassununga, SP, 13635-900, Brazil.
authors.forename: Lenise Freitas
authors.initials: LF
authors.lastname: Mueller
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Humberto
authors.initials: H
authors.lastname: Tonhati
authors.affiliation: Faculdade de Medicina Veterinária e Zootecnia, USP, Pirassununga, SP, 13635-900, Brazil.
authors.forename: Angélica Simone Cravo
authors.initials: ASC
authors.lastname: Pereira
authors.affiliation: Faculdade de Ciências Agrárias e Veterinárias, UNESP, Jaboticabal, SP, 14884-000, Brazil.
authors.forename: Fernando
authors.initials: F
authors.lastname: Baldi
mesh_terms: D000818:Animals; D017849:Animals, Inbred Strains; D001499:Bayes Theorem; D001938:Brazil; D002417:Cattle; D005227:Fatty Acids / Q000032:analysis* / Q000378:metabolism; D005229:Fatty Acids, Monounsaturated / Q000378:metabolism; D015525:Fatty Acids, Omega-3 / Q000378:metabolism; D043371:Fatty Acids, Omega-6 / Q000378:metabolism; D005240:Feasibility Studies; D023281:Genomics / Q000379:methods*; D006801:Humans; D008297:Male; D008460:Meat / Q000032:analysis*; D008957:Models, Genetic; D009124:Muscle Proteins / Q000235:genetics* / Q000378:metabolism; D018482:Muscle, Skeletal / Q000254:growth & development / Q000378:metabolism*; D009753:Nutritive Value; D020641:Polymorphism, Single Nucleotide; D012641:Selection, Genetic
chemical_list: D005227:Fatty Acids; D005229:Fatty Acids, Monounsaturated; D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6; D009124:Muscle Proteins
keywords: Bos indicus; Genomic selection; Lipid profile; Meat quality