title: GIST: Institutional Experience at SRMS-IMS, India.
abstract: Gastro-Intestinal Stromal Tumors (GIST) is a malignant, non-epithelial, mesenchymal tumor of the digestive tract that is not uncommon in clinical practice nowadays; diagnosis being based upon immuno-histo-chemical analysis of the resected or biopsied (FNAC) specimen. Abdominal lump with or without intra-luminal bleed is a common mode of presentation. Early diagnosis and appropriate management with surgery and/or Imatinib therapy improves recurrence free survival and may impact overall survival. We present here our institutional experience of four patients, admitted in Onco-Surgery Dept., with pain abdomen and upper/lower gastrointestinal bleed, which, on subsequent workup were diagnosed to be cases of GIST, were appropriately managed according to their disease stage and show recurrence-free survival on follow-up.
authors.affiliation: Dept. of Surgical Oncology, SRMS-IMS, Bhojipura, Bareilly, India.
authors.forename: Shubhanshu
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Dept. of Surgical Oncology, SRMS-IMS, Bhojipura, Bareilly, India.
authors.forename: Keshri
authors.initials: K
authors.lastname: Amit
authors.affiliation: Dept. of Interventional Radiology, SRMS-IMS, Bhojipura, Bareilly, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Dept. of Pathology, Bhojipura, SRMS-IMS, Bareilly, India.
authors.forename: Tanu
authors.initials: T
authors.lastname: Argawal
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D000068877:Imatinib Mesylate / Q000627:therapeutic use*; D007194:India; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate