title: The relation of anthropometric measurements and insulin resistance in patients with polycystic kidney disease.
abstract: OBJECTIVE
  To examine the frequency of insulin resistance (IR) and its relation with anthropometric measurements in patients with autosomal dominant polycystic kidney disease (ADPKD).
  
  
  METHODS
  Nonobese 82 patients with ADPKD and 58 age matched healthy controls were enrolled into the study. None of participants were diabetic or receiving renal replacement therapies (RRT). IR was determined by homeostasis model assessment of insulin resistance (HOMA-IR) formula. Tanita body composition analyzer was used for anthropometric measurements. Creatinine clearance of participant were assessed by the modification of diet in renal diseases (MDRD).
  
  
  RESULTS
  Patients with ADPKD had significantly higher level of urea and creatinine, microalbuminuria, and lower level of MDRD. Body fat distribution and HOMA-IR in both the groups were similar. Systolic and diastolic blood pressure of patients were higher than those of controls.
  
  
  CONCLUSIONS
  We failed to determine a higher frequency of IR among patients with ADPKD.
authors.affiliation: Department of Nephrology, Acibadem Taksim Hospital, Istanbul, Turkey.
authors.forename: Bennur
authors.initials: B
authors.lastname: Esen
authors.affiliation: Bagcilar Education and Research Hospital, Internal Medicine, Istanbul, Turkey.
authors.forename: Emel Sağlam
authors.initials: ES
authors.lastname: Gokmen
authors.affiliation: Department of Internal Medicine, School of Medicine, Yeni Yuzyil University, Istanbul, Turkey.
authors.forename: Mahmut
authors.initials: M
authors.lastname: Kaya
authors.affiliation: Department of Urology, School of Medicine, Acibadem University, Istanbul, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Ozkan
authors.affiliation: Bagcilar Education and Research Hospital, Internal Medicine, Istanbul, Turkey.
authors.forename: Ahmet Engin
authors.initials: AE
authors.lastname: Atay
keywords: anthropometric measurements; diabetes mellitus; insulin resistance; obesity; polycystic kidney disease