title: Brønsted acid-catalyzed stereoselective [4+3] cycloadditions of ortho-hydroxybenzyl alcohols with N,N'-cyclic azomethine imines.
abstract: The first [4+3] cycloaddition of ortho-hydroxybenzyl alcohols has been established by making use of N,N'-cyclic azomethine imines as suitable 1,3-dipoles under Brønsted acid catalysis. By using this strategy, biologically important seven-membered heterocyclic scaffolds have been constructed in good yields and excellent diastereoselectivities (up to 92% yield, most >95 : 5 dr).
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Guang-Jian
authors.initials: GJ
authors.lastname: Mei
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Zi-Qi
authors.initials: ZQ
authors.lastname: Zhu
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Jia-Jia
authors.initials: JJ
authors.lastname: Zhao
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Chen-Yu
authors.initials: CY
authors.lastname: Bian
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Ruo-Wei
authors.initials: RW
authors.lastname: Chen
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Feng
authors.identifier: http://orcid.org/0000-0003-3922-0708
authors.initials: F
authors.lastname: Shi