title: Human immunodeficiency virus-negative plasmablastic lymphoma: A case report and literature review.
abstract: BACKGROUND
  Plasmablastic lymphoma (PBL) is a rare subtype of human immunodeficiency virus (HIV)-related non-Hodgkin's lymphoma that predominantly manifests in the oral cavity.
  
  
  METHODS
  Three cases of HIV-negative PBL were reported.
  
  
  METHODS
  HIV-negative PBL INTERVENTIONS:: The patient had undergone chemotherapy.
  
  
  RESULTS
  Clinical outcomes were very poor in Cases 1 and 3; Case 2, whose diagnosis suggested no bone marrow involvement, is still alive.
  These cases served to broaden the reported clinical spectrum of HIV-negative PBL. Clinicians and pathologists need to be familiar with lymphoma in the identified extra-oral PBL variation and there levant differential diagnosis procedures for this particular disease.
authors.affiliation: Department of oncology, Institute of Clinical Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou Henan Department of Medical Oncology, Fujian Provincial Hospital, Fuzhou, China.
authors.forename: Li
authors.initials: L
authors.lastname: Lin
authors.forename: Xudong
authors.initials: X
authors.lastname: Zhang
authors.forename: Meng
authors.initials: M
authors.lastname: Dong
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.forename: Xinhua
authors.initials: X
authors.lastname: Wang
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Xiaorui
authors.initials: X
authors.lastname: Fu
authors.forename: Zhenchang
authors.initials: Z
authors.lastname: Sun
authors.forename: Jingjing
authors.initials: J
authors.lastname: Wu
authors.forename: Zhaoming
authors.initials: Z
authors.lastname: Li
authors.forename: Yu
authors.initials: Y
authors.lastname: Chang
authors.forename: Yingjun
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Zhou
authors.forename: Mingzhi
authors.initials: M
authors.lastname: Zhang
authors.forename: Qingjiang
authors.initials: Q
authors.lastname: Chen
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018023:HIV Seronegativity; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069293:Plasmablastic Lymphoma / Q000175:diagnosis* / Q000188:drug therapy; D055815:Young Adult