title: Profile of infections in renal transplant recipients from India.
abstract: BACKGROUND
  Infectious disorders are a major cause of concern in renal transplant recipients (RTRs) leading to considerable morbidity and mortality. We studied the profile and outcomes of infectious disorders in a cohort of RTR.
  
  
  METHODS
  In this prospective, observational study, we evaluated all RTR who presented with the features of infection. We also included asymptomatic patients with microbiological evidence of infection. We excluded patients with acute rejection, drug toxicity, and malignancy. Descriptive statistics were used to analyze the results.
  
  
  RESULTS
  The study population (n= 45, 35 male and 10 female) had a mean age of 35.5 ± 10.4 years and follow-up after transplant was 2.1 ± 1.7 years. Urinary tract infection (UTI,n= 15) is the most common infection followed by tuberculosis (TB,n= 8), cytomegalovirus (n= 6), candidiasis (n= 7), and hepatitis (n= 11). Miscellaneous infections such as cryptosporidiosis and pneumocystis were seen in 10 patients. Simultaneous infections with two organisms were seen in 7 patients. Four patients succumbed to multiorgan dysfunction following sepsis, another 4 patients developed chronic graft dysfunction, while the remaining 35 RTR had a good graft function.
  
  
  CONCLUSIONS
  Infectious complications are very common in the posttransplant period including UTI and TB. Further large scale studies are required to identify the potential risk factors leading to infections in RTR.
authors.affiliation: Department of Nephrology, Command Hospital, Lucknow, Uttar Pradesh, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Department of Nephrology, Command Hospital, Lucknow, Uttar Pradesh, India.
authors.forename: Chaturbhuj
authors.initials: C
authors.lastname: Agarwal
authors.affiliation: Department of Nephrology, Command Hospital, Lucknow, Uttar Pradesh, India.
authors.forename: Ashok K
authors.initials: AK
authors.lastname: Hooda
authors.affiliation: Department of Medicine, AFMC, Pune, Maharashtra, India.
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Ojha
authors.affiliation: Department of Medicine, Military Hospital, Ambala, India.
authors.forename: Mukesh
authors.initials: M
authors.lastname: Dhillon
authors.affiliation: Department of Endocrinology, Army Hospital (R and R), Delhi, India.
authors.forename: K V S
authors.initials: KV
authors.lastname: Hari Kumar
keywords: India; infections; renal transplantation; tuberculosis; urinary tract infection