title: Asymmetric Aziridination of N-Sulphonyl Ketimines with Unfunctionalized Ketones: A One-pot Approach to Multisubstituted Fused Aziridines.
abstract: A highly diastereo- and enantioselective aziridination of N-sulphonyl ketimines with unfunctionalized ketones was reported. In this efficient method, a sequential direct asymmetric Mannich reaction and oxidative C-H amination were involved, which enabled a straightforward route to multisubstituted-fused aziridines in one pot. More importantly, two different products could be selectively obtained in the reaction by adding or removing a metal additive.
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang 473061, P. R. China.
authors.forename: Sheng
authors.identifier: 0000-0002-9686-3921
authors.initials: S
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang 473061, P. R. China.
authors.forename: Lijun
authors.initials: L
authors.lastname: Li
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang 473061, P. R. China.
authors.forename: Lilan
authors.initials: L
authors.lastname: Xin
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang 473061, P. R. China.
authors.forename: Wenmin
authors.initials: W
authors.lastname: Liu
authors.affiliation: College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University , Nanyang 473061, P. R. China.
authors.forename: Kun
authors.initials: K
authors.lastname: Xu