title: ANGIOGRAPHIC SUBTYPES OF POLYPOIDAL CHOROIDAL VASCULOPATHY IN TAIWAN: A Prospective Multicenter Study.
abstract: OBJECTIVE
  To determine the incidence and clinical characteristics of angiographic subtypes of polypoidal choroidal vasculopathy (PCV).
  
  
  METHODS
  It is a prospective, multicenter, cross-sectional study. Patients with newly diagnosed exudative macular degeneration are classified into PCV, age-related macular degeneration (AMD), and retinal angiomatous proliferation. Polypoidal choroidal vasculopathy is further classified into two subtypes depending on the presence (Type 1: polypoidal choroidal neovascularization) or absence (Type 2: typical PCV) of feeder vessels on indocyanine green angiography.
  
  
  RESULTS
  We enrolled 169 patients: 76 (45%) with PCV, 75 (44.4%) with AMD, and 14 (8.3%) with retinal angiomatous proliferation. Of the patients with PCV, 20 (26%) were classified as Type 1 PCV and 56 (74%) were classified as Type 2 PCV. The Type 1 PCV had a similar mean age compared to the AMD group (73.1 ± 9.6 vs. 75.6 ± 8.8 years, P = 0.281) and the Type 2 PCV (68.8 ± 9.6 years) was younger than the AMD group (P < 0.001). Type 1 PCV presented with worse visual acuity compared with the AMD. Both PCV subtypes had a higher incidence of hemorrhagic complications (85% and 75% respectively).
  
  
  CONCLUSIONS
  Type 2 PCV is more common than Type 1 PCV in Taiwan. Our results support the hypothesis that polypoidal choroidal neovascularization and typical PCV may be distinct entities.
authors.affiliation: Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan.|College of Medicine, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Ling
authors.initials: L
authors.lastname: Yeung
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
authors.forename: Chien-Neng
authors.initials: CN
authors.lastname: Kuo
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: An-Ning
authors.initials: AN
authors.lastname: Chao
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Kuan-Jen
authors.initials: KJ
authors.lastname: Chen
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Wei-Chi
authors.initials: WC
authors.lastname: Wu
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
authors.forename: Chien-Hsiung
authors.initials: CH
authors.lastname: Lai
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Nan-Kai
authors.initials: NK
authors.lastname: Wang
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Yih-Shiou
authors.initials: YS
authors.lastname: Hwang
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
authors.forename: Ching-Lung
authors.initials: CL
authors.lastname: Chen
authors.affiliation: College of Medicine, Chang Gung University, Taoyuan, Taiwan.|Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
authors.forename: Chi-Chun
authors.initials: CC
authors.lastname: Lai
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply*; D015862:Choroid Diseases / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D015994:Incidence; D008297:Male; D011127:Polyps / Q000175:diagnosis*; D011446:Prospective Studies; D012171:Retinal Vessels / Q000473:pathology*; D013624:Taiwan / Q000453:epidemiology; D014792:Visual Acuity