title: Hydrophilic Dogwood Extracts as Materials for Reducing the Skin Irritation Potential of Body Wash Cosmetics.
abstract: A significant problem related to the use of surfactants in body wash cosmetics is their propensity to trigger skin irritations. Only scarce literature exists on the effect of plant extracts on the skin irritation potential. The present study is an attempt to determine the effect of hydrophilic dogwood extracts on the irritant potential of body wash gels. Extractants used in the study were water and mixtures of water with glycerine, water with trimethylglycine (betaine), and water with plant-derived glycol (propanediol). The basic biochemical properties, i.e., the ability to neutralize free radicals, and the content of polyphenols, anthocyanins and flavonoids, were determined. An attempt was undertaken to analyze the impact of the extract added to natural body wash gel formulations on product properties. The skin irritation potential was assessed by determining the zein number and the increase in the pH level of the bovine serum albumin (BSA) solution. The viscosity and foaming ability of the resulting products were evaluated. The studies revealed that an addition of dogwood extract contributes to an improvement in the properties of body wash gels and significantly increases the safety of product use through reducing the skin irritation effect.
authors.affiliation: Department of Cosmetology, The University of Information Technology and Management in Rzeszow, Kielnarowa 386a, Tyczyn 36-020, Poland. zniziol@wsiz.rzeszow.pl.
authors.forename: Zofia
authors.initials: Z
authors.lastname: Nizioł-Łukaszewska
authors.affiliation: Department of Cosmetology, The University of Information Technology and Management in Rzeszow, Kielnarowa 386a, Tyczyn 36-020, Poland. posika@wsiz.rzeszow.pl.
authors.forename: Paweł
authors.initials: P
authors.lastname: Osika
authors.affiliation: Department of Chemistry, University of Technology and Humanities in Radom, Chrobrego 27, Radom 26-600, Poland. tomasz.wasilewski@uthrad.pl.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Wasilewski
authors.affiliation: Department of Cosmetology, The University of Information Technology and Management in Rzeszow, Kielnarowa 386a, Tyczyn 36-020, Poland. tbujak@wsiz.rzeszow.pl.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Bujak
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D029768:Cornus / Q000737:chemistry*; D003358:Cosmetics / Q000737:chemistry* / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D064209:Phytochemicals / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D059808:Polyphenols / Q000737:chemistry; D012867:Skin / Q000187:drug effects; D014783:Viscosity
chemical_list: D000975:Antioxidants; D003358:Cosmetics; D005419:Flavonoids; D064209:Phytochemicals; D010936:Plant Extracts; D059808:Polyphenols
keywords: Cornus mas; antioxidant activity; cosmetic safety; extract; irritation potential