title: Gut microbiota: Implications in Parkinson's disease.
abstract: Gut microbiota (GM) can influence various neurological outcomes, like cognition, learning, and memory. Commensal GM modulates brain development and behavior and has been implicated in several neurological disorders like Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, anxiety, stress and much more. A recent study has shown that Parkinson's disease patients suffer from GM dysbiosis, but whether it is a cause or an effect is yet to be understood. In this review, we try to connect the dots between GM and PD pathology using direct and indirect evidence.
authors.affiliation: Jaypee University of Information Technology, Waknaghat, District- Solan, Himachal Pradesh, PIN-173234, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Parashar
authors.affiliation: Jaypee University of Information Technology, Waknaghat, District- Solan, Himachal Pradesh, PIN-173234, India. Electronic address: udayabanu.m@juit.ac.in.
authors.forename: Malairaman
authors.initials: M
authors.lastname: Udayabanu
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D003071:Cognition / Q000187:drug effects; D000069196:Gastrointestinal Microbiome / Q000187:drug effects; D006801:Humans; D010300:Parkinson Disease / Q000382:microbiology* / Q000503:physiopathology*; D019936:Probiotics / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotics; Fecal transplant; Germ-free; Gut microbiota; Parkinson's disease; Probiotics