title: Dexamethasone as an Adjuvant to Bupivacaine in Supraclavicular Brachial Plexus Block in Paediatrics for Post-operative Analgesia.
abstract: BACKGROUND
  Sensory blockade of the brachial plexus with local anaesthetics for perioperative analgesia leads to stable haemodynamics intraoperatively, smoother emergence from general anaesthesia and decreased need for supplemental analgesics or suppositories in the Post-operative period. However, increasing the duration of local anaesthetic action is often desirable because it prolongs surgical anaesthesia and analgesia. Various studies in adults prove that steroids increase the duration of action of local anaesthetics when used as adjuncts.
  
  
  OBJECTIVE
  The study aimed at determining the efficacy of dexame-thasone as an adjuvant to bupivacaine for Post-operative analgesia following sensory blockade of the brachial plexus in paediatrics.
  
  
  METHODS
  The study was divided into two groups of 15 each, group BD receiving dexamethasone (0.1mg/kg) as an adjunct to bupivacaine 0.125% and group B receiving bupivacaine alone. The duration of analgesia was taken as time from completion of the block to the patient receiving rescue analgesia, the haemodynamics were measured until 180 minutes after surgery, the incidence of Post-operative Nausea and Vomiting (PONV) was measured.
  
  
  RESULTS
  The duration of analgesia in the group BD was 27.1±13.4 hours and was significantly higher as compared to the group B, in which it was 13.9±11.3 hours (p<0.05). The pulse rate measured Post-operatively between both groups at 20 minutes (p-value 0.634), 60 minutes (p-value 0.888), 120 minutes (p-value 0.904) and 180 minutes (p-value 0.528) showed no statistical significance. Likewise the mean blood pressure measured between the two groups at 20 minutes, 60 minutes, 120 minutes and 180 minutes Post-operatively showed no significance. There was no significant difference in incidence of PONV in both groups with p-value of 0.624.
  
  
  CONCLUSIONS
  Dexamethasone as an adjuvant to local anaesthetic in brachial plexus blocks significantly, prolongs duration of analgesia in children undergoing upper limb surgeries.
authors.affiliation: Assistant Professor, Department of Anesthesiology, Father Muller Medical College , Mangalore, Karnataka, India .
authors.forename: Karl Sa
authors.initials: KS
authors.lastname: Ribeiro
authors.affiliation: Senior Resident, Department of Anesthesiology, Father Muller Medical College , Mangalore, Karnataka, India .
authors.forename: Anjali
authors.initials: A
authors.lastname: Ollapally
authors.affiliation: Assistant Professor, Department of Anesthesiology, Kasturba Medical College , Mangalore, Karnataka, India .
authors.forename: Julie
authors.initials: J
authors.lastname: Misquith
keywords: Post-operative analgesia; Stable haemodynamics; Ultrasound; Wong baker scale