title: Helicobacter pylori: The Past, Present, and Future in Management.
abstract: Helicobacter pylori is a common bacterial pathogen responsible for substantial gastrointestinal morbidity worldwide. Helicobacter pylori infection can be clinically challenging, given the numerous diagnostic and therapeutic options available. In this article, we provide a systematic review of H pylori epidemiology and pathogenesis. In addition, we provide a simplified approach to the diagnosis and treatment of H pylori infection, suitable for application in the primary care setting. On completion of this article, one should be able to (1) state the indications for H pylori testing; (2) identify noninvasive and invasive tests to diagnose H pylori infection; and (3) describe the advantages and disadvantages of various treatment regimens.
authors.affiliation: Department of Internal Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Amrit K
authors.initials: AK
authors.lastname: Kamboj
authors.affiliation: Department of Internal Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Cotter
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address: oxentenko.amy@mayo.edu.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Oxentenko
mesh_terms: D019468:Disease Management; D016481:Helicobacter Infections / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D016480:Helicobacter pylori / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D054539:Medication Therapy Management; D011320:Primary Health Care / Q000379:methods