title: [Frequency of increased thyrotropin in women with hyperprolactinemia].
abstract: BACKGROUND
  Hypothyroidism has been associated to hyperprolactinemia. The aim was to establish the frequency of high thyrotropin (TSH) levels in women with hyperprolactinemia.
  
  
  METHODS
  Retrospective, observational, open, and non-controlled study, which included all the non-pregnant women whose prolactin (PRL) and TSH levels were measured between January 1 and December 31, 2014.
  
  
  RESULTS
  437 women were studied. The most frequent diagnoses that motivated PRL measurement were: infertility (31.7%), polycystic ovary syndrome (18.7%), and amenorrhea (7.8%). In the whole group TSH levels were 2.5 ± 2.7 µUl/mL and those of PRL 16.5 ± 13.2 ng/dL. From the total of women, those with normal PRL levels, 1.4% had low TSH levels, 76.6% normal and 7.5% high, while in those with high PRL levels 0.7% had low TSH levels 12.6% normal and 1.1% high. Of those 374 patients with normal PRL, 6 (1.6%) had low TSH levels, 335 (89.6%) normal TSH levels, and 33 (8.8%) high TSH levels. Of those 63 patients with high PRL, 3 (4.8%) had low TSH levels, 55 (87.3%) normal TSH and 5 (7.9%) high TSH levels.
  
  
  CONCLUSIONS
  In this study it was not possible to document that the proportion of patients with high TSH was greater in those with hyperprolactinemia.
authors.affiliation: División de Investigación en Salud, Hospital de Ginecoobstetricia 4 "Luis Castelazo Ayala", Instituto Mexicano del Seguro Social, Ciudad de México, México. drsebastiancarranza@gmail.com.
authors.forename: Sebastián
authors.initials: S
authors.lastname: Carranza-Lira
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Daza-Carrasco
authors.forename: Rosario
authors.initials: R
authors.lastname: Chán-Verdugo
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D011388:Prolactin / Q000097:blood; D012189:Retrospective Studies; D013972:Thyrotropin / Q000097:blood*
chemical_list: D015415:Biomarkers; D011388:Prolactin; D013972:Thyrotropin
keywords: Hypothyroidism; Prolactin; Thyroid-stimulating hormone