title: Comparison of topical oxybuprocaine and intravenous fentanyl in pediatric strabismus surgery.
abstract: OBJECTIVE
  To compare the outcomes such as postoperative nausea/vomiting, analgesic requirements, and hospital stay following the use of topical oxybuprocaine hydrochloride 0.4% or intravenous (IV) fentanyl in children undergoing strabismus surgery.
  
  
  METHODS
  This was a prospective cohort study. Children operated under general anesthesia for strabismus were given topical oxybuprocaine hydrochloride 0.4% (Group T) and IV fentanyl (Group F) before surgery. The episodes of nausea/vomiting, pain score, requirement of additional analgesia during postoperative period, and duration of hospital stay were compared in two groups.
  
  
  RESULTS
  There were 47 children in Group T and 59 children in Group F. The median pain score in two groups were 2.38 (25% quartile; 2.0) and 3.00 (25% quartile; 3.00), respectively. The difference was significant (K WP< 0.03). The episodes of nausea/vomiting in two groups were in 2 and 6 children in Group T and Group F, respectively. The median hospital stay of children of Group T and Group F were 242 and 285 min, respectively. The difference was not statistically significant (P= 0.22).
  
  
  CONCLUSIONS
  Using intraoperative topical oxybuprocaine drops, one can achieve better analgesic outcomes and reduce risk of nausea and vomiting compared to intravenous opioid analgesics and therefore, the hospital stay could also be marginally reduced.
authors.affiliation: Department of Anesthesia, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Yousafzai
authors.affiliation: Department of Anesthesia, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
authors.forename: Abdul
authors.initials: A
authors.lastname: Zahoor
authors.affiliation: Department of Anesthesiology and Reanimatology, Russian People's Friendship University, State Prize Laureate of USSR, Moscow, Russia.
authors.forename: Butrov
authors.initials: B
authors.lastname: Andrey
authors.affiliation: Department of Anesthesia, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
authors.forename: Nauman
authors.initials: N
authors.lastname: Ahmad
keywords: Analgesia; pain score; strabismus