title: Carbamazepine Toxicity-Induced Spindle Coma: A Novel Case Report.
abstract: A 9-year-old girl presented with alleged history of deliberate ingestion of 4 g of carbamazepine, following which she became comatose. A bedside electroencephalogram (EEG) was performed to rule out nonconvulsive status epilepticus, which showed presence of spindle coma (SC), not reactive to noxious stimuli. Following hemodialysis, a second EEG showed absence of SC and complete clinical recovery. We present this unique case of carbamazepine-induced SC, thereby highlighting the extent of the etiologic spectrum of SC and discussing the literature related to this association.
authors.affiliation: Narayana Institute of Neurosciences, Narayana Health City, Bangalore, Karnataka, India.
authors.forename: Bhumir
authors.initials: B
authors.lastname: Chauhan
authors.forename: Amitkumar
authors.initials: A
authors.lastname: Patanvadiya
authors.forename: Gopal Krishna
authors.initials: GK
authors.lastname: Dash
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects; D002220:Carbamazepine / Q000009:adverse effects*; D002648:Child; D003128:Coma / Q000139:chemically induced*; D062787:Drug Overdose / Q000628:therapy; D004569:Electroencephalography; D005260:Female; D006801:Humans; D006435:Renal Dialysis
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine