title: Generation of cycloalkynes through deprotonation of cyclic enol triflates with magnesium bisamides.
abstract: Deprotonative generation of cyclohexynes, cycloheptynes, and cyclooctynes was achieved by controlling the reactivities of transient anionic species from the corresponding enol triflates with magnesium bis(2,2,6,6-tetramethylpiperidide) as a base. The starting enol triflates are readily obtained through triflation of the corresponding ketones, allowing direct access to the cycloalkynes.
authors.affiliation: Department of Chemical Science and Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan. okano@harbor.kobe-u.ac.jp.
authors.forename: Yuto
authors.initials: Y
authors.lastname: Hioki
authors.affiliation: Department of Chemical Science and Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan. okano@harbor.kobe-u.ac.jp.
authors.forename: Kentaro
authors.identifier: http://orcid.org/0000-0003-2029-8505
authors.initials: K
authors.lastname: Okano
authors.affiliation: Department of Chemical Science and Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan. okano@harbor.kobe-u.ac.jp.
authors.forename: Atsunori
authors.initials: A
authors.lastname: Mori