title: When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema.
abstract: Angioedema is a severe form of an allergic reaction characterized by the localized edematous swelling of the dermis and subcutaneous tissues. Angiotensin-converting enzyme inhibitor-induced angioedema (ACEI-IA) is an allergic reaction that can be severe in some cases requiring advanced management measures. Fresh frozen plasma has been used off-labeled in some case reports to improve and to prevent worsening of the angioedema in a few cases of ACEI-IA. We are reporting this case to increase the awareness of physicians and to widen their therapeutic options when encountering this clinically significant condition.
authors.affiliation: Internal Medicine, University of Central Florida College of Medicine.
authors.forename: Gerard
authors.initials: G
authors.lastname: Chaaya
authors.affiliation: Internal Medicine, University of Central Florida College of Medicine.
authors.forename: Faraz
authors.initials: F
authors.lastname: Afridi
authors.affiliation: Internal Medicine, University of Central Florida College of Medicine.
authors.forename: Arfa
authors.initials: A
authors.lastname: Faiz
authors.affiliation: Pulmonary/Critical Care, Osceola Regional Medical Center.
authors.forename: Ali
authors.initials: A
authors.lastname: Ashraf
authors.affiliation: Internal Medicine, University of Central Florida College of Medicine.
authors.forename: Mahrukh
authors.initials: M
authors.lastname: Ali
authors.affiliation: Internal Medicine, University of Central Florida College of Medicine.
authors.forename: Analia
authors.initials: A
authors.lastname: Castiglioni
keywords: angioedema; angiotensin-converting enzyme inhibitor; fresh frozen plasma