title: [Clinical value of the evolution of left ventricular global strain in anterior myocardial infarction patients treated with emergency percutaneous coronary intervention].
abstract: To investigate the evolution of left ventricular global strain in anterior myocardial infarction patients treated with emergency percutaneous coronary intervention (PCI).  Methods: A total of 54 patients with PCI were enrolled as a PCI group. Forty healthy subjects were enrolled as a control group. Dynamic cardiac images were collected. All of these images were analyzed off-line by velocity vector imaging (VVI) software. N-terminal pro-B-type natriuretic peptide (NT-proBNP) was measured with an electrochemiluminescence immunoassay through the Elecsys 1010/2010 system. Correlation analysis were undertaken between VVI and NT-proBNP levels in blood.  Results: In PCI group, only globle longitudinal strain (GLS) was significantly increased 3 day after operation (P<0.05). GLS and globle circumferencial strain (GCS) were markedly increased 6 months after operation (P<0.05). In PCI group, left ventricular GLS 1 d to 6 months after PCI shows positive correlation with lgNT-proBNP levels (r=0.66, P<0.001). GLS value was -12.50% at the 3rd day after operation, indicating the improvment of cardiac function in the first and sixth month after PCI.  Conclusion: The change of Left ventricular globle longitudinal systolic function after emergency PCI may be more sensitive to the improvement of myocardial stunning after STEMI reperfusion; GLS value (-12.50%) at the 3rd day after operation predict the improvment of cardiac function in the first and sixth months after PCI.
authors.affiliation: Department of Ultrasonography, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Zurong
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Department of Ultrasonography, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Qichang
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: Department of Cardiovascular Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Zhenfei
authors.initials: Z
authors.lastname: Fang
authors.affiliation: Department of Ultrasonography, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Danming
authors.initials: D
authors.lastname: Cao
authors.affiliation: Department of Ultrasonography, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Jiawei
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Department of Ultrasonography, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Xiankui
authors.initials: X
authors.lastname: Tan
mesh_terms: D000368:Aged; D056988:Anterior Wall Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D015415:Biomarkers; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D005260:Female; D006321:Heart; D006352:Heart Ventricles / Q000737:chemistry* / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion / Q000009:adverse effects / Q000534:rehabilitation; D017682:Myocardial Stunning / Q000503:physiopathology / Q000628:therapy; D020097:Natriuretic Peptide, Brain / Q000737:chemistry*; D010446:Peptide Fragments; D062645:Percutaneous Coronary Intervention / Q000534:rehabilitation*; D011379:Prognosis; D000072657:ST Elevation Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013599:Systole; D016277:Ventricular Function, Left
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain