title: Examiner's finger-mounted near-infrared spectroscopy is feasible to analyze cerebral and skeletal muscle oxygenation in conscious Chihuahuas.
abstract: To measure regional saturation of oxygen ( rSO 2 ) of hemoglobin and total hemoglobin index (HbI) in the brain (through the molera of the head) and skeletal muscle (musculus gracilis) of conscious Chihuahua dogs using an examiner’s finger-mounted near-infrared spectroscopy (NIRS) device, Toccare, we investigated brain and skeletal muscle NIRS in 48 Chihuahuas without severe disease. To measure rSO 2 and total HbI, a Toccare probe was placed on the molera of the head and musculus gracilis of each dog for real-time recording. Stable NIRS values were obtained within 10 s. We also examined the effect of anesthesia on rSO 2 and total HbI of a Chihuahua. Cerebral rSO 2 values ( 59 % ± 7 % ) were significantly lower than those obtained at femoral regions ( 67 % ± 6 % ), whereas total HbI values in the brain ( 0.38 ± 0.09 ) were significantly higher than those of the musculus gracilis ( 0.20 ± 0.05 ). Sedation with a combination of medetomidine and ketamine decreased cerebral rSO 2 along with a corresponding reduction in heart rate. Sevoflurane anesthesia with 100% O 2 maintained rSO 2 in the brain with a
authors.affiliation: Nippon Veterinary and Life Science University, Laboratory of Comparative Medicine, School of Veterinary Medicine, Musashino, Tokyo, JapanbAnimal Medical Center of Gotemba Inter, Gotemba, Shizuoka, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Hiwatashi
authors.affiliation: Doi Pet Clinic, Fujieda, Shizuoka, Japan.
authors.forename: Kimiaki
authors.initials: K
authors.lastname: Doi
authors.affiliation: Tsukuba International University, Department of Medical Technology, Faculty of Health Sciences, Tsuchiura, Ibaraki, Japan.
authors.forename: Risuke
authors.initials: R
authors.lastname: Mizuno
authors.affiliation: Nippon Veterinary and Life Science University, Laboratory of Comparative Medicine, School of Veterinary Medicine, Musashino, Tokyo, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Yokosuka
mesh_terms: D000777:Anesthetics / Q000494:pharmacology; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D002560:Cerebrovascular Circulation / Q000187:drug effects; D004285:Dogs; D006454:Hemoglobins / Q000032:analysis; D018482:Muscle, Skeletal / Q000737:chemistry* / Q000187:drug effects; D010100:Oxygen / Q000032:analysis; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation*
chemical_list: D000777:Anesthetics; D006454:Hemoglobins; D010100:Oxygen