title: A B-cell lymphoma case that is unclassifiable, and intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma of lacrimal gland.
abstract: A 60-year-old woman presented with acute eyelid swelling and a subcutaneous hemorrhage in the right eye. Magnetic resonance imaging showed a spherical tumor of the lacrimal gland. The tumor was removed by the Kroenlein method. We diagnosed as a B-cell lymphoma that is unclassifiable, and intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) (intermediate DLBCL/BL) based on its immunohistopathological examination andc-MYC/IgHrearrangement. We administered six cycles of dose-adjusted-EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin hydrochloride, and rituximab) therapy, and remission of the lymphoma was obtained. This is the first case of an intermediate DLBCL/BL of a lacrimal gland.
authors.affiliation: Department of Ophthalmology.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yunoki
authors.affiliation: Department of Gastroenterology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama.
authors.forename: Jun
authors.initials: J
authors.lastname: Murakami
authors.affiliation: Department of Ophthalmology, Osaka Kaisei Hospital, Osaka.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Imagawa
authors.affiliation: Department of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
authors.forename: Takahiko
authors.initials: T
authors.lastname: Nakajima
authors.affiliation: Department of Ophthalmology.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hayashi
keywords: Burkitt lymphoma; c-MYC gene; diffuse large B-cell lymphoma; fluorescence in situ hybridization