title: Genus Kitasatospora, taxonomic features and diversity of secondary metabolites.
abstract: The genus Kitasatospora was proposed in 1982. Although Kitasatospora strains resemble Streptomyces strains in morphology, they are clearly different in cell-wall composition, as they contain both LL- and meso-diaminopimelic acid. Aerial and submerged spores contain LL-, while vegetative and submerged mycelia contain mainly meso- in their cell walls. Currently, 23 species have been validly proposed. Members of the genus Kitasatospora form a tight cluster and represent a legitimate genus distinct from Streptomyces on the basis of phylogenetic analysis of 16S rRNA gene sequences. A variety of biologically active compounds have been found from Kitasatospora strains and structures of these compounds are extremely diverse. Genome sequences of 15 strains published so far are about 7-9 Mb in size and contain many genes governing secondary metabolites.
authors.affiliation: Kitasato Institute for Life Sciences, Kitasato University, Minato-ku, Tokyo, Japan.
authors.forename: Yōko
authors.initials: Y
authors.lastname: Takahashi
mesh_terms: D002473:Cell Wall / Q000737:chemistry; D016680:Genome, Bacterial; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics*; D064210:Secondary Metabolism / Q000235:genetics*; D017423:Sequence Analysis, RNA; D013045:Species Specificity; D013302:Streptomyces / Q000145:classification / Q000235:genetics; D013306:Streptomycetaceae / Q000145:classification / Q000235:genetics* / Q000378:metabolism
chemical_list: D012336:RNA, Ribosomal, 16S