title: Primary Lacrimal Sac Melanoma With Metastatic Cervical Disease: A Review of the Literature and Case Report.
abstract: Primary melanoma arising from the nasolacrimal sac is a rare form of mucosal melanoma, with only 30 cases previously reported in the literature and none reporting cervical metastatic disease. Given the extremely rare nature of this disease, specific guidelines for staging and intervention are impractical and do not exist. As such, case presentations have formed the basis for management. This report describes the only case to the authors' knowledge of primary nasolacrimal sac mucosal melanoma with cervical metastatic disease at the time of diagnosis, which was detected only with positron emission tomographic computer tomography, and briefly reviews the existing published cases to help assist in the development of a general algorithm for patient care.
authors.affiliation: Fellow, Department of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, Hampshire, UK. Electronic address: shivassubramaniam@gmail.com.
authors.forename: Shiva S
authors.initials: SS
authors.lastname: Subramaniam
authors.affiliation: Consultant, Department of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, Hampshire, UK.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Anand
authors.affiliation: Consultant, Department of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, Hampshire, UK.
authors.forename: Timothy K
authors.initials: TK
authors.lastname: Mellor
authors.affiliation: Consultant, Department of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, Hampshire, UK.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Brennan
mesh_terms: D005134:Eye Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000556:secondary*; D008875:Middle Aged; D009301:Nasolacrimal Duct; D009333:Neck