title: Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil.
abstract: The positional distribution pattern of fatty acids (FAs) in the triacylglycerols (TAGs) affects intestinal absorption of these FAs. The aim of this study was to compare lymphatic absorption of pinolenic acid (PLA) present in structured pinolenic TAG (SPT) where PLA was evenly distributed on the glycerol backbone, with absorption of pine nut oil (PNO) where PLA was predominantly positioned at the sn-3 position. SPT was prepared via the nonspecific lipase-catalyzed esterification of glycerol with free FA obtained from PNO. Lymphatic absorption of PLA from PNO and from SPT was compared in a rat model of lymphatic cannulation. Significantly (P < 0.05) greater amounts of PLA were detected in lymph collected for 8 h from an emulsion containing SPT (28.5 ± 0.7% dose) than from an emulsion containing PNO (26.2 ± 0.6% dose), thereby indicating that PLA present in SPT has a greater capacity for lymphatic absorption than PLA from PNO.
authors.affiliation: Korea Food Research Institute , Seongnam 13539, Korea.
authors.forename: Min-Yu
authors.initials: MY
authors.lastname: Chung
authors.affiliation: Department of Food Science and Technology, Chung-Ang University , Anseong 17546, Korea.
authors.forename: Hyunjoon
authors.initials: H
authors.lastname: Woo
authors.affiliation: Department of Food and Nutrition, Changwon National University , Changwon 51140, Korea.
authors.forename: Juyeon
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Food and Nutrition, Changwon National University , Changwon 51140, Korea.
authors.forename: Daecheol
authors.initials: D
authors.lastname: Kong
authors.affiliation: Korea Food Research Institute , Seongnam 13539, Korea.
authors.forename: Hee-Don
authors.initials: HD
authors.lastname: Choi
authors.affiliation: Korea Food Research Institute , Seongnam 13539, Korea.
authors.forename: In-Wook
authors.initials: IW
authors.lastname: Choi
authors.affiliation: Department of Food and Nutrition, Korea University , Seoul 02841, Korea.
authors.forename: In-Hwan
authors.initials: IH
authors.lastname: Kim
authors.affiliation: Department of Food and Nutrition, Changwon National University , Changwon 51140, Korea.
authors.forename: Sang K
authors.initials: SK
authors.lastname: Noh
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University , Seoul 04310, Korea.
authors.forename: Byung Hee
authors.identifier: http://orcid.org/0000-0002-4599-6775
authors.initials: BH
authors.lastname: Kim
mesh_terms: D000818:Animals; D004951:Esterification; D007408:Intestinal Absorption; D008042:Linolenic Acids / Q000737:chemistry* / Q000378:metabolism*; D008196:Lymph / Q000737:chemistry / Q000378:metabolism*; D008297:Male; D015394:Molecular Structure; D009754:Nuts / Q000737:chemistry / Q000378:metabolism; D028223:Pinus / Q000737:chemistry / Q000378:metabolism*; D010938:Plant Oils / Q000737:chemistry / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014280:Triglycerides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D008042:Linolenic Acids; D010938:Plant Oils; D014280:Triglycerides; C034302:5,9,12-octadecatrienoic acid
keywords: Novozym 435; lymphatic absorption; pinolenic acid; stereospecific numbering position; structured triacylglycerols