title: A 54-year-old male with rapidly progressive neurologic syndrome: Clinicopathologic correlation of a rare diagnosis.
abstract: Diagnosis of systemic lupus erythematosus (SLE) as primary presentation with central nervous system involvement as a rapidly progressive neurologic syndrome is extremely rare. We present a rare case of a 54-year-old hypertensive male patient, who presented with a fulminant neurologic syndrome. He presented with cerebellar and meningeal signs, aseptic meningitis and had a rapid downhill course following admission. A postmortem revealed feature of systemic connective tissue fulfilling diagnostic criteria of SLE with lupus cerebritis.
authors.affiliation: Department of Pathology, Command Hospital Air Force, Bengaluru, Karnataka, India.
authors.forename: Deepti
authors.initials: D
authors.lastname: Mutreja
authors.affiliation: Department of Pathology, Command Hospital Air Force, Bengaluru, Karnataka, India.
authors.forename: Nikhil
authors.initials: N
authors.lastname: Moorchung
authors.affiliation: Department of Medicine, Command Hospital Air Force, Bengaluru, Karnataka, India.
authors.forename: Salil
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Department of Medicine, Command Hospital Air Force, Bengaluru, Karnataka, India.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Saxena
authors.affiliation: Department of Pathology, Command Hospital Air Force, Bengaluru, Karnataka, India.
authors.forename: Rohini S
authors.initials: RS
authors.lastname: Doshetty
authors.affiliation: Department of Medicine, Command Hospital Air Force, Bengaluru, Karnataka, India.
authors.forename: Bhaskar
authors.initials: B
authors.lastname: Nandi
mesh_terms: D001344:Autopsy; D002493:Central Nervous System Diseases / Q000209:etiology* / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D008875:Middle Aged