title: Disassembly Control of Saccharide-Based Amphiphiles Driven by Electrostatic Repulsion.
abstract: According to the design of disassembly using electrostatic repulsion, novel amphiphiles consisting of a lipophilic ion part and a hydrophilic saccharide part were synthesized via the facile copper-catalyzed click reaction, and their molecular assemblies in water and chloroform were studied. The amphiphiles exhibited a molecular orientation opposite to that of the conventional amphiphiles in each case. ζ Potential measurements indicated that the lipophilic ion part is exposed outside in chloroform. The size of a solvophobic part in the amphiphiles dominates the size of an assembling structure; that is, in water, these amphiphiles tethering different lengths of the saccharide part exhibited almost identical assembling size, whereas in chloroform, the size depends on the length of the saccharide part in the amphiphiles.
authors.affiliation: Graduate School of Chemical Sciences and Engineering and ‡Faculty of Science, Hokkaido University , Kita10 Nishi8, Kita-ku, Sapporo, Hokkaido 060-0810, Japan.
authors.forename: Taihei
authors.initials: T
authors.lastname: Yamada
authors.affiliation: Graduate School of Chemical Sciences and Engineering and ‡Faculty of Science, Hokkaido University , Kita10 Nishi8, Kita-ku, Sapporo, Hokkaido 060-0810, Japan.
authors.forename: Kenta
authors.identifier: 0000-0003-3880-9094
authors.initials: K
authors.lastname: Kokado
authors.affiliation: Graduate School of Chemical Sciences and Engineering and ‡Faculty of Science, Hokkaido University , Kita10 Nishi8, Kita-ku, Sapporo, Hokkaido 060-0810, Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Sada
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D003300:Copper; D057927:Hydrophobic and Hydrophilic Interactions; D055672:Static Electricity
chemical_list: D002241:Carbohydrates; D003300:Copper