title: Localization patterns of dopamine active transporter synthesizing cells during development of brine shrimp.
abstract: There have been many studies on dopamine active transporter (DAT) in humans and laboratory animals; however, there is a lack of information on DAT in brine shrimp. In this study, we demonstrated the neuronal and nonneuronal characteristics of DAT-synthesizing (DAT+cells) during development of brine shrimp. In neuronal cells, the DAT+neurons in the central body and lobes of a protocerebrum (PC) controlled the deutocerebrum. The sensory cells of nauplius eyes projected their decussated axons to the PC, and the DAT+cells at the posterior region were associated with migration and control of the 10 posterior neurons during the early nauplius stage. In nonneuronal cells, the five types of glands, that is, the salt, antennal, mandible, and accessory glands and posterior gland1 and gland2 synthesized DAT protein. In addition, the gut and rectum dilator muscles and renal cells expressed DAT protein. Thus, DAT protein acts in the development of several types of cells during development of brine shrimp.
authors.affiliation: Department of Clinical Laboratory Sciences, College of Health Science, Korea University, Seoul, Korea.
authors.forename: Bo Yong
authors.initials: BY
authors.lastname: Kim
authors.affiliation: Department of Clinical Laboratory Sciences, College of Health Science, Korea University, Seoul, Korea.
authors.forename: Gyeong Hee
authors.initials: GH
authors.lastname: Shin
authors.affiliation: Department of Laboratory Medicine, Kangwon National University, School of Medicine, Chuncheon, Gangwon-do, Korea.
authors.forename: In Soo
authors.initials: IS
authors.lastname: Lee
authors.affiliation: Department of Clinical Laboratory Sciences, College of Health Science, Korea University, Seoul, Korea.
authors.forename: Suhng Wook
authors.initials: SW
authors.lastname: Kim
authors.affiliation: Department of Clinical Laboratory Sciences, College of Health Science, Korea University, Seoul, Korea.
authors.forename: Ho Seung
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Department of Biomedical Laboratory Science, College of Health Science, Jungwon University, Geo-San, Republic of Korea.
authors.forename: Jin Kwan
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Clinical Laboratory Sciences, College of Health Science, Korea University, Seoul, Korea.
authors.forename: Seung Gwan
authors.initials: SG
authors.lastname: Lee
mesh_terms: D000818:Animals; D001156:Artemia / Q000166:cytology* / Q000254:growth & development / Q000378:metabolism; D050483:Dopamine Plasma Membrane Transport Proteins / Q000378:metabolism*; D059290:Dopaminergic Neurons
chemical_list: D050483:Dopamine Plasma Membrane Transport Proteins
keywords: Artemia; arthropods; crustacean; dopamine; invertebrates; monoamine transporter