title: Long-Term Implant Survival After 100 Maxillary Sinus Augmentations Using Plasma Rich in Growth Factors.
abstract: OBJECTIVE
  To identify determinants of long-term implant survival after sinus augmentation procedure (SAP) using a combination of plasma rich in growth factors (PRGF) and graft material.
  
  
  METHODS
  Patients were included in this retrospective study if they underwent SAP through a lateral wall approach using PRGF in combination with mainly xenograft, and received implants restored for at least 1 year. Sociodemographic, behavioral and implant characteristics (clinical factors, implant details, surgical details, prosthesis details, and complications) were analyzed.
  
  
  RESULTS
  Sixty-seven patients received 217 implants in 100 augmented sinuses. The mean follow-up was 7.2 years. Overall, 22 implants failed in 15 patients (90% cumulative implant survival). Multivariable models showed greater implant survival with implants placed with ≥5 mm of residual crestal bone height (RBH) compared with those placed with <3 mm of RBH. There was also an improvement in survival comparing implant lengths. In addition, immediate loading of implants significantly increased the risk of implant failure.
  
  
  CONCLUSIONS
  The use of PRGFs for maxillary sinus grafting may be an effective and safe treatment option for the rehabilitation of atrophic edentulous posterior maxillae. However, randomized clinical trials are needed to confirm these findings.
authors.affiliation: *Associate Director of Periodontology & Implant Dentistry, Bluestone Center for Clinical Research, New York, NY; Clinical Assistant Professor, Department of Oral and Maxillofacial Surgery, New York University College of Dentistry, New York, NY. †Periodontology and Oral Surgery, Private Practice, A Coruña, Spain. ‡Clinical Assistant Professor, Department of Stomatology II, School of Dentistry, Complutense University of Madrid, Madrid, Spain. §Clinical Professor and Director of Clinical Research, Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, NY.
authors.forename: Ismael
authors.initials: I
authors.lastname: Khouly
authors.forename: Simón
authors.initials: S
authors.lastname: Pardiñas López
authors.forename: Ignacio
authors.initials: I
authors.lastname: Aliaga
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Froum
mesh_terms: D003758:Dental Implantation, Endosseous / Q000379:methods* / Q000706:statistics & numerical data; D019232:Dental Restoration Failure / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010949:Plasma / Q000378:metabolism; D012189:Retrospective Studies; D012307:Risk Factors; D059546:Sinus Floor Augmentation / Q000379:methods* / Q000706:statistics & numerical data
chemical_list: D036341:Intercellular Signaling Peptides and Proteins