title: Trends in colorectal cancer in the Caribbean: A population-based study in Martinique, 1982-2011.
abstract: BACKGROUND
  We aimed to describe incidence and mortality from colorectal cancer, and temporal trends between 1982 and 2011 in Martinique (French West-Indies).
  
  
  METHODS
  This was a descriptive, longitudinal, observational study based on data from the Martinique cancer registry. The study included all incident cases of colorectal cancer between 1982 and 2011. We recorded sociodemographic data and clinical variables (histology, site according to the WHO classification). Cancer cases were recorded in strict conformity with the international standards. Annual rate of change was calculated, direct standardisation was used for incidence and mortality age standardised rates (ASR). The comparative incidence figure and comparative mortality figure (95% confidence intervals) were calculated.
  
  
  RESULTS
  In total, 2530 patients were included in our study; 1243 died. In the period 2007-2011, a considerable increase in incidence was observed, making colorectal cancer the second leading cause of cancer deaths in both sexes (8.9% and 10.5%). In men, ASR for incidence increased from 9.6/100,000 person-years in the period 1982-1986 to 27.2/100,000 person-years in the period 2007-2011, with a notable acceleration of the increase. In women, ASR increased from 8.4 to 19.8/100,000 person-years over the same periods. For the latest period 2007-2011, mortality rates were 9.9 and 7.6/100,000 person-years for men and for women respectively. Regardless of the sex, there was a strong increase in the incidence of right colon cancer, which became the most common colorectal site in women in Martinique.
  
  
  CONCLUSIONS
  Our findings confirm the increase in the incidence of colorectal cancer that started in the 2000s. Trends observed reflect a salient epidemiological transition of the Caribbean.
authors.affiliation: University hospital of Martinique, oncology haematology urology pathology department, UF 1441 cancer research and registry, 97261 Fort-de-France, Martinique. Electronic address: clarisse.joachim@chu-fortdefrance.fr.
authors.forename: C
authors.initials: C
authors.lastname: Joachim
authors.affiliation: University hospital of Martinique, oncology haematology urology pathology department, UF 1441 cancer research and registry, 97261 Fort-de-France, Martinique.
authors.forename: J
authors.initials: J
authors.lastname: Véronique-Baudin
authors.affiliation: University hospital of Martinique, oncology haematology urology pathology department, 97261 Fort-de-France, Martinique.
authors.forename: M
authors.initials: M
authors.lastname: Razanakaivo
authors.affiliation: University hospital of Martinique, oncology haematology urology pathology department, UF 1441 cancer research and registry, 97261 Fort-de-France, Martinique.
authors.forename: J
authors.initials: J
authors.lastname: Macni
authors.affiliation: AMREC, 97232 Fort-de-France, Martinique.
authors.forename: A
authors.initials: A
authors.lastname: Pomier
authors.affiliation: Laboratoire de pathologie SERAL, 97233 Fort-de-France, Martinique.
authors.forename: M-J
authors.initials: MJ
authors.lastname: Dorival
authors.affiliation: University of French West Indies, EA 929-Biosphères, 97157 Fort-de-France, Martinique.
authors.forename: J
authors.initials: J
authors.lastname: Smith-Ravin
authors.affiliation: University hospital of Martinique, oncology haematology urology pathology department, UF 1441 cancer research and registry, 97261 Fort-de-France, Martinique.
authors.forename: O
authors.initials: O
authors.lastname: Pierre-Louis
authors.affiliation: University hospital of Martinique, oncology haematology urology pathology department, 97261 Fort-de-France, Martinique.
authors.forename: P
authors.initials: P
authors.lastname: Escarmant
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017691:Caribbean Region; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008395:Martinique / Q000453:epidemiology; D008875:Middle Aged; D009026:Mortality / Q000639:trends; D012042:Registries; D055815:Young Adult
keywords: Cancer colorectal; Colorectal cancer; Epidemiology; Incidence; Mortality; Mortalité; Topographie; Topography; Épidémiologie