title: An unusual cause of renal failure; Epstein syndrome.
abstract: Epstein syndrome constitutes macrothrombocytopenia without neutrophil inclusion bodies along with deafness and renal failure. A diagnosis of Epstein syndrome was made in a 17 year-old-male patient with macrothrombopathic thrombocytopenia, renal failure and sensorineural hearing loss. Our patient is unique as he presented with rapidly progressive renal failure and developed chronic kidney disease in second decade of life with no symptomatic hearing loss or bleeding tendency. Epstein syndrome needs to be differentiated from Alport syndrome which is more common disease with similar clinical presentation.
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Manish R
authors.initials: MR
authors.lastname: Balwani
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Divyesh P
authors.initials: DP
authors.lastname: Engineer
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Manoj R
authors.initials: MR
authors.lastname: Gumber
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Vivek B
authors.initials: VB
authors.lastname: Kute
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Himanshu V
authors.initials: HV
authors.lastname: Patel
authors.affiliation: Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, Dr. HL Trivedi Institute of Transplantation Sciences Ahmedabad, India.
authors.forename: Aruna V
authors.initials: AV
authors.lastname: Vanikar
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Dinesh
authors.initials: D
authors.lastname: Gera
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Pankaj R
authors.initials: PR
authors.lastname: Shah
authors.affiliation: Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center.
authors.forename: Hargovind L
authors.initials: HL
authors.lastname: Trivedi
keywords: Chronic kidney disease; Deafness; Epstein Syndrome; Hemodialysis; Megathrombocytopenia