title: Recent Progress in the Chemistry of Daphniphyllum Alkaloids †.
abstract: Daphniphyllum is an evergreen species known since 1826. After initial systematic investigations, more than 320 members of this family have been isolated, which comprise complex and fascinating structures. Unique azapolycyclic architectures containing one or more quaternary stereocenters render these alkaloids synthetically challenging. This review covers efforts toward the synthesis of Daphniphyllum alkaloids spanning the period from 2005 to the beginning of 2016, including reported biological activities as well as the isolation of new members of this genus.
authors.affiliation: Department of Chemistry, Université de Montréal , Post Office Box 6128, Station Centre Ville, Montreal, Quebec H3C 3J7, Canada.
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Chattopadhyay
authors.affiliation: Department of Chemistry, Université de Montréal , Post Office Box 6128, Station Centre Ville, Montreal, Quebec H3C 3J7, Canada.
authors.forename: Stephen
authors.identifier: http://orcid.org/0000-0003-3582-6972
authors.initials: S
authors.lastname: Hanessian
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D031995:Saxifragaceae / Q000737:chemistry*
chemical_list: D000470:Alkaloids