title: Cervical length measurement: Comparison of transabdominal and transvaginal approach.
abstract: Objective: To compare transabdominal (TA) and transvaginal (TV) ultrasound assessment of cervical length at 16-41 weeks gestation.Methods: TA and TV ultrasound measurements of cervical length were made on 491 pregnancies of 16-41 weeks gestation. Cervical length was measured from internal to external cervical os. Bland-Altman plots and Wilcoxon signed rank test were used to evaluate differences between TA and TV measurements.Results: The validity of the TA method depended on cervical length. Although the TA method underestimated cervical length by 2.0 mm on average (P< 0.001), Bland Altman plots showed an inverse trend with shorter cervixes. In women with a cervix < 25 mm (n = 30) based on TV scan measurement, TA overestimated cervical length by 12 mm (P < 0.001). The sensitivity and specificity of TA as a test to detect cervical length < 25 mm were 10% (95% CI: 2.1-26%) and 94% (95% CI: 92-96%) respectively; the negative LR was 0.96 (95% CI: 0.84-1.08). The maximum area under the ROC curve would be obtained at a TA cut-off = 32 mm (to detect a cervix < 25 mm), corresponding to a sensitivity of 77% and a specificity of 58%.Conclusion: TA measurements do not reflect TV assessment accurately, particularly if the cervix is short. At 24-34 weeks, a policy of proceeding to TV scan if TA measurement is < 25 mm will only detect 10% of affected pregnancies and has a poor positive predictive value so is of limited value as a predictive tool for women attending with symptoms and signs of preterm labour > 24 weeks gestation. There is no value in TA assessment of the cervix > 36 weeks.
authors.affiliation: Northern Women's ImagingSydneyNew South WalesAustralia; Discipline of Obstetrics Gynaecology and NeonatologyFaculty of MedicineUniversity of SydneySydneyNew South WalesAustralia.
authors.forename: Susan Campbell
authors.initials: SC
authors.lastname: Westerway
authors.affiliation: Department of Obstetrics and GynaecologyInstitute of Clinical MedicineAarhus UniversityAarhusDenmark; RPA Women and BabiesRoyal Prince Alfred HospitalSydneyNew South WalesAustralia.
authors.forename: Lars Henning
authors.initials: LH
authors.lastname: Pedersen
authors.affiliation: RPA Women and BabiesRoyal Prince Alfred HospitalSydneyNew South WalesAustralia; Discipline of Obstetrics Gynaecology and NeonatologyFaculty of MedicineUniversity of SydneySydneyNew South WalesAustralia.
authors.forename: Jon
authors.initials: J
authors.lastname: Hyett
keywords: cervical length; preterm labour; risk prediction; ultrasound