title: Unusual Destruction of the Nasal Septum.
abstract: Extranodal Natural Killer/T-cell lymphoma (ENKTL) is the most common cause of nasal cell lymphoma. It manifests by progressive destruction of the facial midline features with nasal obstruction and local destruction of soft tissue. Therefore, establishing the diagnosis of this disease tends to be difficult. This is attributed to an extensive differential diagnosis of infectious, autoimmune, neoplastic and inflammatory etiologies. We herein report the case of a 63-year-old female who presented to our department for persistent nasal congestion resistant to symptomatic treatment that was found to have an ENKTL. In this paper, we discuss the pathogenesis, clinical and imaging findings, differential diagnosis, prognosis and treatment.
authors.affiliation: Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
authors.forename: Tarek
authors.initials: T
authors.lastname: Assi
authors.affiliation: Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
authors.forename: Elie
authors.initials: E
authors.lastname: El Rassy
authors.affiliation: Radiology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
authors.forename: Tania
authors.initials: T
authors.lastname: Moussa
authors.affiliation: Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
authors.forename: Samer
authors.initials: S
authors.lastname: Tabchi
authors.affiliation: Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
authors.forename: Ralph
authors.initials: R
authors.lastname: Chebib
authors.affiliation: Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
authors.forename: Marwan
authors.initials: M
authors.lastname: Ghosn
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D054391:Lymphoma, Extranodal NK-T-Cell / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D009300:Nasal Septum / Q000473:pathology*; D011379:Prognosis