title: [Principles «cliff» pancreatic necrosis in a first-aid hospital].
abstract: BACKGROUND
  Pancreatic necrosis - acute surgical disease accompanying high rates of mortality and complications.
  
  
  METHODS
  The analysis of the treatment of 256 patients with pancreatic necrosis moderate and severe degrees. In the control group was conducted basic therapy, the main (n=158), which further were administered high doses of octreotide and endoscopic stenting of the main pancreatic duct to decrease the intraductal pressure, prevention and treatment of internal pancreatic fistula.
  
  
  CONCLUSIONS
  In the main group in contrast to the control is marked by a more rapid decline in the level of amylase, lipase and leukocyte index of intoxication. The infection occurred in the basic - 11%, control 20% died in the study group - 3%, control - 9%.
authors.affiliation: A.I. Evdokimov Moscow State medical dental University, Moscow, Russia.
authors.forename: M D
authors.initials: MD
authors.lastname: Dibirov
authors.affiliation: A.I. Evdokimov Moscow State medical dental University, Moscow, Russia.
authors.forename: L V
authors.initials: LV
authors.lastname: Domarev
authors.affiliation: A.I. Evdokimov Moscow State medical dental University, Moscow, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Shitikov
authors.affiliation: A.I. Evdokimov Moscow State medical dental University, Moscow, Russia.
authors.forename: A I
authors.initials: AI
authors.lastname: Isayev
authors.affiliation: A.I. Evdokimov Moscow State medical dental University, Moscow, Russia.
authors.forename: G S
authors.initials: GS
authors.lastname: Karsotiyan
mesh_terms: D003131:Combined Modality Therapy / Q000379:methods; D019299:Decompression, Surgical / Q000295:instrumentation / Q000379:methods; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D005260:Female; D005765:Gastrointestinal Agents / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000008:administration & dosage*; D010043:Outcome and Process Assessment, Health Care; D010179:Pancreas / Q000473:pathology / Q000601:surgery; D010185:Pancreatic Fistula / Q000209:etiology / Q000517:prevention & control; D019283:Pancreatitis, Acute Necrotizing / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control*; D012426:Russia / Q000453:epidemiology; D012720:Severity of Illness Index; D015607:Stents
chemical_list: D005765:Gastrointestinal Agents; D015282:Octreotide