title: Meta-QTL for resistance to white mold in common bean.
abstract: White mold, caused by the fungus Sclerotinia sclerotiorum (Lib.) de Bary, is a major disease that limits common bean production and quality worldwide. The host-pathogen interaction is complex, with partial resistance in the host inherited as a quantitative trait with low to moderate heritability. Our objective was to identify meta-QTL conditioning partial resistance to white mold from individual QTL identified across multiple populations and environments. The physical positions for 37 individual QTL were identified across 14 recombinant inbred bi-parental populations (six new, three re-genotyped, and five from the literature). A meta-QTL analysis of the 37 QTL was conducted using the genetic linkage map of Stampede x Red Hawk population as the reference. The 37 QTL condensed into 17 named loci (12 previously named and five new) of which nine were defined as meta-QTL WM1.1, WM2.2, WM3.1, WM5.4, WM6.2, WM7.1, WM7.4, WM7.5, and WM8.3. The nine meta-QTL had confidence intervals ranging from 0.65 to 9.41 Mb. Candidate genes shown to express under S. sclerotiorum infection in other studies, including cell wall receptor kinase, COI1, ethylene responsive transcription factor, peroxidase, and MYB transcription factor, were found within the confidence interval for five of the meta-QTL. The nine meta-QTL are recommended as potential targets for MAS for partial resistance to white mold in common bean.
authors.affiliation: Department of Biology, Federal University of Lavras, Lavras, Minas Gerais, Brazil.
authors.forename: Renato C C
authors.initials: RC
authors.lastname: Vasconcellos
authors.affiliation: Irrigated Agriculture Research and Extension Center, Washington State University, Prosser, Washington, United States of America.
authors.forename: O Blessing
authors.initials: OB
authors.lastname: Oraguzie
authors.affiliation: USDA-ARS, Grain Legume Genetics and Physiology Research Unit, Prosser, Washington, United States of America.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Soler
authors.affiliation: Department of Horticulture, Oregon State University, Corvallis, Oregon, United States of America.
authors.forename: Haidar
authors.initials: H
authors.lastname: Arkwazee
authors.affiliation: Department of Horticulture, Oregon State University, Corvallis, Oregon, United States of America.
authors.forename: James R
authors.initials: JR
authors.lastname: Myers
authors.affiliation: Área de Cultivos Hortofrutícolas y Forestales, Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Villaviciosa, Asturias, Spain.
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Ferreira
authors.affiliation: USDA-ARS, Soybean Genomics and Improvement Laboratory, Beltsville, Maryland, United States of America.
authors.forename: Qijian
authors.initials: Q
authors.lastname: Song
authors.affiliation: Department of Plant Sciences, North Dakota State University, Fargo, North Dakota, United Sates of America.
authors.forename: Phil
authors.initials: P
authors.lastname: McClean
authors.affiliation: USDA-ARS, Grain Legume Genetics and Physiology Research Unit, Prosser, Washington, United States of America.
authors.forename: Phillip N
authors.initials: PN
authors.lastname: Miklas
mesh_terms: D001203:Ascomycota / Q000235:genetics*; D002874:Chromosome Mapping; D032461:Chromosomes, Plant / Q000737:chemistry / Q000235:genetics; D060467:Disease Resistance / Q000235:genetics*; D008040:Genetic Linkage; D005838:Genotype; D009195:Peroxidase / Q000235:genetics / Q000378:metabolism; D027805:Phaseolus / Q000235:genetics* / Q000382:microbiology; D010935:Plant Diseases / Q000235:genetics / Q000382:microbiology; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism
chemical_list: D010940:Plant Proteins; D014157:Transcription Factors; D009195:Peroxidase