title: Improving the Catalytic Performance of (S)-Proline as Organocatalyst in Asymmetric Aldol Reactions in the Presence of Solvate Ionic Liquids: Involvement of a Supramolecular Aggregate.
abstract: For the first time, a highly efficient and stereoselective asymmetric aldol reaction employing (S)-proline in the presence of solvate ionic liquids is reported. The reaction seems to proceed via a supramolecular aggregate of (S)-proline, the solvate ionic liquid, and water, affording high yields and excellent stereoselectivities with low catalyst loadings.
authors.affiliation: Departamento de Química, Centro de Investigación y de Estudios Avanzados , Av. IPN 2508, 07360 Ciudad de México, México.
authors.forename: Arturo
authors.initials: A
authors.lastname: Obregón-Zúñiga
authors.affiliation: Departamento de Química, Centro de Investigación y de Estudios Avanzados , Av. IPN 2508, 07360 Ciudad de México, México.
authors.forename: Mario
authors.initials: M
authors.lastname: Milán
authors.affiliation: Departamento de Química, Centro de Investigación y de Estudios Avanzados , Av. IPN 2508, 07360 Ciudad de México, México.|El Colegio Nacional, Luis González Obregón 23, Centro Histórico, 06020 Ciudad de México, México.
authors.forename: Eusebio
authors.identifier: 0000-0003-0936-7020
authors.initials: E
authors.lastname: Juaristi