title: Unusual Anemias.
abstract: Many processes lead to anemia. This review covers anemias that are less commonly encountered in the United States. These anemias include hemoglobin defects like thalassemia, bone marrow failure syndromes like aplastic anemia and pure red cell aplasia, and hemolytic processes such as paroxysmal nocturnal hemoglobinuria. The pathogenesis, diagnostic workup, and treatment of these rare anemias are reviewed.
authors.affiliation: Division of Hematology/Medical Oncology, Department of Medicine, Oregon Health Sciences University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97201-3098, USA.
authors.forename: Molly Maddock
authors.initials: MM
authors.lastname: Daughety
authors.affiliation: Division of Hematology/Medical Oncology, Department of Medicine, Oregon Health Sciences University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97201-3098, USA; Division of Hematology/Medical Oncology, Department of Medicine, Knight Cancer Institute, Oregon Health and Science University, MC L586, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA. Electronic address: delought@ohsu.edu.
authors.forename: Thomas G
authors.initials: TG
authors.lastname: DeLoughery
mesh_terms: D000740:Anemia / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy; D000741:Anemia, Aplastic / Q000188:drug therapy / Q000503:physiopathology; D000743:Anemia, Hemolytic / Q000503:physiopathology; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D001855:Bone Marrow Diseases / Q000503:physiopathology; D000080983:Bone Marrow Failure Disorders; D002056:Burns / Q000150:complications; D003300:Copper / Q000172:deficiency; D064420:Drug-Related Side Effects and Adverse Reactions; D006457:Hemoglobinuria, Paroxysmal / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D044342:Malnutrition / Q000150:complications; D012010:Red-Cell Aplasia, Pure / Q000139:chemically induced / Q000503:physiopathology; D013789:Thalassemia / Q000503:physiopathology
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D007166:Immunosuppressive Agents; D003300:Copper; C481642:eculizumab
keywords: Aplastic anemia; Burns; Drug induced; Paroxysmal nocturnal hemoglobinuria; Spur cell anemia; Thalassemia