title: Pregnancy-related osteoporosis and spinal fractures.
abstract: Pregnancy-related osteoporosis is a very rare condition characterized by the occurrence of fracture during pregnancy or the puerperium. Despite its relative rarity, it can be a dangerous condition that causes severe back pain, height loss and disability. Normal physiologic changes during pregnancy, genetic or racial difference, obstetrical history and obstetrical disease, such as preterm labor or pregnancy-induced hypertension, are presumed risk factors of pregnancy-related osteooporosis. However, exact etiology and pathogenesis are uncertain. The management and natural history are still poorly defined. Traditional medications for osteoporosis are calcium/vitamin D and bisphosphonate. Concerns with bisphosphonate include accumulation in bone and fetal exposure in subsequent pregnancies. The newly developed medication, teriparatide, has shown good results. We report six cases of pregnancy-related osteoporosis and spinal fracture with literature review.
authors.affiliation: Medical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Ka Yeong
authors.initials: KY
authors.lastname: Yun
authors.affiliation: Medical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Si Eun
authors.initials: SE
authors.lastname: Han
authors.affiliation: Medical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Seung Chul
authors.initials: SC
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, Korea.
authors.forename: Jong Kil
authors.identifier: 0000-0002-6338-1512
authors.initials: JK
authors.lastname: Joo
authors.affiliation: Medical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Kyu Sup
authors.initials: KS
authors.lastname: Lee
keywords: Fractures; Osteoporosis; Pregnancy; compression