title: Rhodium-Catalyzed Intermolecular Carbonylative [2 + 2 + 1] Cycloaddition of Alkynes Using Alcohol as the Carbon Monoxide Source for the Formation of Cyclopentenones.
abstract: A highly regioselective rhodium-catalyzed intermolecular carbonylative [2 + 2 + 1] cycloaddition of alkynes using alcohol as a CO surrogate to access 4-methylene-2-cyclopenten-1-ones has been developed. In this transformation, the alcohol performs multiple roles, including generating the Rh-H intermediate, functioning as the CO source, and assisting in the isomerization of the alkyne. Alkynes can act as both the olefin and the alkyne partner in the cyclopentenone core.
authors.affiliation: Department of Chemistry, College of Natural Sciences, Seoul National University , Seoul 08826, Republic of Korea.
authors.forename: Ju Hyun
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Chemistry, College of Natural Sciences, Seoul National University , Seoul 08826, Republic of Korea.
authors.forename: Taemoon
authors.initials: T
authors.lastname: Song
authors.affiliation: Department of Chemistry, College of Natural Sciences, Seoul National University , Seoul 08826, Republic of Korea.
authors.forename: Young Keun
authors.identifier: 0000-0002-2837-5176
authors.initials: YK
authors.lastname: Chung