title: Physical Activity is Associated with Metabolic Health in Men Living with HIV.
abstract: Metabolic health is a cause for concern among those living with HIV, especially those on antiretroviral therapy. Physical activity (PA) is known to benefit metabolic health, however, few studies have objectively measured PA or investigated the relationship between PA and metabolic health among those living with HIV. In this study, PA and indices of metabolic health among twenty men living with HIV and twenty age matched HIV-negative men were measured. PA was measured using Actigraph accelerometers. Components of the metabolic syndrome and insulin resistance were measured using routine laboratory methods. Men living with HIV were significantly more physically active than HIV-negative men, and were reaching public PA guidelines. Significant inverse correlations between moderate PA and both insulin resistance (ρ -0.847; p < 0.001) and triglycerides (ρ -0.575; p = 0.013) were seen in those living with HIV. Results of this study emphasize the importance of an active lifestyle for those living with HIV.
authors.affiliation: Discipline of Physiotherapy, University of Dublin, Trinity College, Dublin, Ireland. c.forde@tcd.ie.
authors.forename: Cuisle
authors.identifier: http://orcid.org/0000-0001-9961-6144
authors.initials: C
authors.lastname: Forde
authors.affiliation: Department of Genito Urinary Medicine and Infectious Diseases, Saint James's Hospital, Dublin, Ireland.
authors.forename: Aisling
authors.initials: A
authors.lastname: Loy
authors.affiliation: Department of Genito Urinary Medicine and Infectious Diseases, Saint James's Hospital, Dublin, Ireland.
authors.forename: Siobhan
authors.initials: S
authors.lastname: O'Dea
authors.affiliation: Department of Genito Urinary Medicine and Infectious Diseases, Saint James's Hospital, Dublin, Ireland.
authors.forename: Fiona
authors.initials: F
authors.lastname: Mulcahy
authors.affiliation: Discipline of Physiotherapy, University of Dublin, Trinity College, Dublin, Ireland.
authors.forename: John
authors.initials: J
authors.lastname: Gormley
authors.affiliation: Department of Cardiology, Saint James's Hospital, Dublin, Ireland.
authors.forename: Caroline
authors.initials: C
authors.lastname: Daly
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D015444:Exercise; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D018023:HIV Seronegativity; D006801:Humans; D007494:Ireland; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology; D008875:Middle Aged; D009043:Motor Activity; D010809:Physical Fitness; D057185:Sedentary Behavior
chemical_list: D019380:Anti-HIV Agents
keywords: HIV; Metabolic syndrome; Physical activity; Sedentary behavior