title: Clinical statistics of gynecologic cancers in Japan.
abstract: Cervical, endometrial, and ovarian cancers, have both high morbidity and mortality among the gynecologic malignant tumors in Japan. The present study was conducted using both the population-based cancer registry and the gynecologic cancer registry to elucidate the characteristics of gynecologic malignant tumors in Japan. Based on nationwide estimates from the population-based cancer registry in Japan, the morbidities and mortality of cervical, endometrial, and ovarian cancers were obtained and used for analysis. Clinicopathologic factors for cervical cancer, endometrial cancer, ovarian cancer, including age, clinical stage, postsurgical stage, histological type, therapeutic strategy, and prognosis were retrieved from the gynecologic cancer registry published by the Japan Society of Obstetrics and Gynecology and used for analysis. The morbidities of cervical, endometrial, and ovarian cancers were 10,908, 13,606, and 9,384 women in 2012, respectively. The prevalence of endometrial cancer has significantly and consistently been increasing and represents the most common gynecologic malignant tumor in Japan. The mortalities of cervical, endometrial, and ovarian cancers were 2.1, 1.3, and 3.2 per 100,000 in 2012, respectively. In 2014, 52.2% of cervical cancer patients were classified as stage I, 22.5% as stage II, 10.2% as stage III, and 11.2% as stage IV. In addition, 71.9% of endometrial cancer patients were classified as stage I, 6.0% as stage II, 13.3% as stage III, and 7.5% as stage IV. Finally, 43.2% of ovarian cancer patients were classified as stage I, 9.1% as stage II, 27.6% as stage III, and 7.2% as stage IV. Twelve-point six percent of ovarian cancer patients received neoadjuvant chemotherapy.
authors.affiliation: Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan. gami@z8.keio.jp.|Gynecologic Tumor Committee, Japan Society of Obstetrics and Gynecology, Tokyo, Japan.
authors.forename: Wataru
authors.identifier: 0000-0003-3925-6057
authors.initials: W
authors.lastname: Yamagami
authors.affiliation: Gynecologic Tumor Committee, Japan Society of Obstetrics and Gynecology, Tokyo, Japan.|Department of Obstetrics and Gynecology, Yamagata University School of Medicine, Yamagata, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Nagase
authors.affiliation: Department of Clinical Research Network, Clinical Research, Innovation and Education Center, Tohoku University Hospital, Sendai, Japan.
authors.forename: Fumiaki
authors.identifier: 0000-0001-9201-1089
authors.initials: F
authors.lastname: Takahashi
authors.affiliation: Gynecologic Tumor Committee, Japan Society of Obstetrics and Gynecology, Tokyo, Japan.|Department of Obstetrics and Gynecology, Wakayama Medical University, Wakayama, Japan.
authors.forename: Kazuhiko
authors.identifier: 0000-0002-6198-0730
authors.initials: K
authors.lastname: Ino
authors.affiliation: Gynecologic Tumor Committee, Japan Society of Obstetrics and Gynecology, Tokyo, Japan.|Department of Obstetrics and Gynecology, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
authors.forename: Toru
authors.identifier: 0000-0003-2888-2538
authors.initials: T
authors.lastname: Hachisuga
authors.affiliation: Gynecologic Tumor Committee, Japan Society of Obstetrics and Gynecology, Tokyo, Japan.|Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Daisuke
authors.identifier: 0000-0002-9596-8326
authors.initials: D
authors.lastname: Aoki
authors.affiliation: Gynecologic Tumor Committee, Japan Society of Obstetrics and Gynecology, Tokyo, Japan.|Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
authors.forename: Hidetaka
authors.identifier: 0000-0002-2403-6134
authors.initials: H
authors.lastname: Katabuchi
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology* / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000628:therapy; D003430:Cross-Sectional Studies; D016889:Endometrial Neoplasms / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging / Q000706:statistics & numerical data; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000628:therapy; D015995:Prevalence; D011379:Prognosis; D012042:Registries; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000628:therapy
keywords: Genital Neoplasms, Female; Japan; Mortality; Neoplasms; Prevalence; Registries; Stage