title: Exercise timing and blood lactate concentrations in individuals with type 2 diabetes.
abstract: The purpose of this study was to characterize how resistance exercise prior to or after a meal alters fasting and postprandial blood lactate concentrations in individuals with type 2 diabetes. Obese individuals with type 2 diabetes (N = 12) completed three 2-day trials, including (i) no exercise (NoEx), (ii) resistance exercise prior to dinner (Ex-M), and (iii) resistance exercise beginning at 45 min postdinner (M-Ex). During day 1 of each trial, fasting and postprandial blood lactate concentrations, perceived exertion, and substrate oxidation were measured, and subsequently on day 2 the following morning fasting blood lactate was measured. The premeal lactate incremental area under the curve (iAUC) during Ex-M (109 ± 66 mmol·L-1·1.6 h-1) was over 100-fold greater (P < 0.01) compared with NoEx (-15 ± 24 mmol·L-1·1.6 h-1) and M-Ex (-2 ± 18 mmol·L-1·1.6 h-1). The postprandial lactate iAUC during M-Ex (304 ± 116 mmol·L-1·4 h-1) was over 2-fold greater (P < 0.01) compared with NoEx (149 ± 74 mmol·L-1·4 h-1) and Ex-M (-140 ± 196 mmol·L-1·4 h-1). Average lactate during exercise was ∼45% greater (P = 0.03) during M-Ex (3.2 ± 0.9 mmol/L) compared with Ex-M (2.2 ± 0.9 mmol/L), but the change in lactate during Ex-M (2.4 ± 1.6 mmol/L) or M-Ex (2.3 ± 1.3 mmol/L) was not different (P > 0.05). Perceived exertion, substrate oxidation, or fasting blood lactate concentrations the day after testing were not different between trials. Blood lactate concentrations during acute resistance exercise are greater when exercise is performed in the postprandial period. Acute resistance exercise performed the night prior does not alter fasting blood lactate concentrations the following morning.
authors.affiliation: Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65211, USA.|Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65211, USA.
authors.forename: Timothy D
authors.initials: TD
authors.lastname: Heden
authors.affiliation: Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65211, USA.|Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65211, USA.
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65211, USA.|Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65211, USA.
authors.forename: Jill A
authors.initials: JA
authors.lastname: Kanaley
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000188:drug therapy; D004032:Diet; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000097:blood; D019344:Lactic Acid / Q000097:blood*; D008297:Male; D062407:Meals; D008687:Metformin / Q000627:therapeutic use; D008875:Middle Aged; D009765:Obesity / Q000097:blood; D019518:Postprandial Period; D055070:Resistance Training; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D014280:Triglycerides; D019344:Lactic Acid; D008687:Metformin
keywords: acide lactique; diabète de type 2; entraînement avec des haltères; exercise timing; lactic acid; meal timing; moment de l’exercice; moment du repas; type 2 diabetes; weight training