title: Assessing the Adequacy of Small Solute Clearance for Various Dialysis Modalities, with Inclusion of Residual Native Kidney Function.
abstract: Measurement of small molecule clearance remains important in the clinical care of patients requiring long-term dialysis. Many patients maintain a significant degree of residual native kidney function and may have nontraditional schedules with or without combined dialysis modalities. In this review, we examine and outline methods for comparing small molecule clearances among various dialysis prescriptions and modalities, with inclusion of residual kidney urea clearance.
authors.affiliation: Department of Medicine, Davis School of Medicine, University of California, Sacramento, California.
authors.forename: Andrew I
authors.initials: AI
authors.lastname: Chin
authors.affiliation: Department of Medicine, Davis School of Medicine, University of California, Sacramento, California.
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Depner
authors.affiliation: Department of Medicine, University of Illinois College of Medicine, Chicago, Illinois.
authors.forename: John T
authors.initials: JT
authors.lastname: Daugirdas
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D003404:Creatinine / Q000097:blood*; D005919:Glomerular Filtration Rate / Q000502:physiology*; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D008954:Models, Biological; D006435:Renal Dialysis; D014508:Urea / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D014508:Urea; D003404:Creatinine