title: Gingival Fibrosarcoma in a Horse.
abstract: A 4-year-old thoroughbred cross mare was referred to the University of Edinburgh Veterinary School Equine Hospital for treatment of a soft tissue tumor on the buccal gingival margin of the rostral right maxillary cheek teeth. The lesion was initially surgically excised and diagnosed as a fibrosarcoma via histopathology. Adjunctive treatment with intralesional cisplatin chemotherapy was begun. The tumor recurred and was repeatedly treated with intralesional cisplatin injections and additional surgical resection over the course of 14 weeks. Despite the initial poor response to treatment, no further regrowth of the tumor occurred 3 months following its final treatment. The horse remained free of visible evidence of tumor nearly 5 years later.
authors.affiliation: 1 University Veterinary Specialists, 2810 Washington Road, McMurray, PA, USA.
authors.forename: Apryle
authors.initials: A
authors.lastname: Horbal
authors.affiliation: 2 Equine Hospital, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, United Kingdom.
authors.forename: Padraic M
authors.initials: PM
authors.lastname: Dixon
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D005887:Gingival Neoplasms / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis / Q000628:therapy*; D006736:Horses; D008437:Maxilla; D009364:Neoplasm Recurrence, Local / Q000662:veterinary
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin
keywords: equine oral fibrosarcoma; equine oral mass; equine oral neoplasia; fibrosarcoma; horse