title: Tropical pulmonary eosinophilia: effect of addition of corticosteroids after failure of diethylcarbamazine therapy.
abstract: Successful response in diethylcarbamazine (DEC) therapy in tropical pulmonary eosinophilia (TPE) is not universal with a 20-40% failure rates in chronic cases. Corticosteroids have been used in such patients. However, their role in management remains ill-defined. A patient of TPE with incomplete clinical, haematological and physiological response to a standard 3 weeks DEC therapy received additional corticosteroids for the next two cycles, after which complete remission occurred. However, there was a relapse two months later with evidence of a chronic state requiring further treatment with corticosteroids with good response.
authors.forename: Manu
authors.initials: M
authors.lastname: Madan
authors.forename: Pawan
authors.initials: P
authors.lastname: Gupta
authors.forename: Richa
authors.initials: R
authors.lastname: Mittal
authors.affiliation: skchhabra@mailcity.com.
authors.forename: Sunil K
authors.initials: SK
authors.lastname: Chhabra
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D003371:Cough / Q000209:etiology; D004049:Diethylcarbamazine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D012129:Respiratory Function Tests
chemical_list: D000305:Adrenal Cortex Hormones; D004049:Diethylcarbamazine
keywords: corticosteroids; diethylcarbamazine; tropical pulmonary eosinophilia