title: Responsive Thiolactone-Derived N-Substituted Poly(Urethane-Amide)s.
abstract: AB' type monomers containing a thiolactone unit and vinyl ether moiety have been prepared with high yields. Aminolysis of the thiolactone moiety generates the corresponding thiol in situ, and upon UV-irradiation, radical polyaddition occurs in the same medium, yielding linear poly(amide-urethane)s with different side chain residues and (Poly(Ethylene Oxide)) PEO-like backbone. Moreover, these unique polymers feature lower critical solution temperature behavior in water. Systematic modification of the responsive polymers reveals the influence of the variation of the side chains and the backbone structure on the corresponding solubility properties. In selected cases, multiresponsive polymers have been developed, which also respond to pH and metal concentration.
authors.affiliation: Department of Organic and Macromolecular Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4-bis, B-9000, Ghent, Belgium.
authors.forename: Pieter
authors.initials: P
authors.lastname: Espeel
authors.affiliation: Department of Organic and Macromolecular Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4-bis, B-9000, Ghent, Belgium.
authors.forename: Sensu
authors.initials: S
authors.lastname: Celasun
authors.affiliation: Department of Organic and Macromolecular Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4-bis, B-9000, Ghent, Belgium.
authors.forename: Pinar Sinem
authors.initials: PS
authors.lastname: Omurtag
authors.affiliation: Department of Organic and Macromolecular Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4-bis, B-9000, Ghent, Belgium.
authors.forename: Steven
authors.initials: S
authors.lastname: Martens
authors.affiliation: Department of Organic and Macromolecular Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4-bis, B-9000, Ghent, Belgium.
authors.forename: Filip E
authors.initials: FE
authors.lastname: Du Prez
mesh_terms: D007783:Lactones / Q000737:chemistry*; D015394:Molecular Structure; D011140:Polyurethanes / Q000138:chemical synthesis* / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D007783:Lactones; D011140:Polyurethanes; D013438:Sulfhydryl Compounds
keywords: aminolysis; polyaddition; responsive polymers; thiol-ene; thiolactone