title: Subtle.Nets.Finder: finely tuned interaction networks in DNA/RNA/protein complexes.
abstract: Graphical Abstract Subtle.Nets.Finder is a workflow of algorithms for identification of subtly interacting groups in DNA/RNA/protein complexes. It is founded on detailed and sophisticated evaluation of the self-consistency in the cooperative network of residue interactions via a combination of advanced calculations (fast multipole method and statistical mechanics) supplemented with graph-theoretical procedures.
authors.affiliation: Nuclear Magnetic Resonance Lab, Institute of Organic Chemistry, Bulgarian Academy of Sciences, U Reduta, Na Baira, Sofia, 1000, Bulgaria. alexkant@orgchm.bas.bg.
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Kantardjiev
mesh_terms: D000465:Algorithms; D019295:Computational Biology; D003198:Computer Simulation; D004247:DNA / Q000737:chemistry / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics; D030562:Databases, Protein; D046911:Macromolecular Substances / Q000737:chemistry*; D025941:Protein Interaction Mapping; D011506:Proteins / Q000737:chemistry / Q000235:genetics*; D012313:RNA / Q000737:chemistry / Q000235:genetics*; D016601:RNA-Binding Proteins / Q000737:chemistry / Q000235:genetics; D013329:Structure-Activity Relationship
chemical_list: D004268:DNA-Binding Proteins; D046911:Macromolecular Substances; D011506:Proteins; D016601:RNA-Binding Proteins; D012313:RNA; D004247:DNA