title: Outcomes of autograft alone versus PEEK+ autograft interbody fusion in the treatment of adult lumbar isthmic spondylolisthesis.
abstract: OBJECTIVE
  Bone resulting from a complete resection of the posterior arch can be cut into an autograft bone that contains the facet joint structure and morselised bone for interbody fusion. However, whether a strut autograft that contains this trimmed facet joint can produce the same clinical and radiographic outcomes as a cage for interbody fusion remains unclear. The aim of this study was to compare the outcomes of a local facet joint autograft alone to those of polyetheretherketone (PEEK)+autograft for posterior lumbar interbody fusion (PLIF) in the treatment of adult isthmic spondylolisthesis.
  
  
  METHODS
  A retrospective analysis was performed on 84 patients with single lumbar isthmic spondylolisthesis who were treated with a local facet joint autograft alone (group A; n=44) or PEEK+autograft (group B; n=40) in PLIF with a minimum follow-up period of 24 months. Pain and disability were assessed using the visual analogue scale, Oswestry disability index and Kirkaldy-Willis criteria. In the radiological evaluation, disc height, slippage reduction, and fusion status were examined. Postoperative complications were also monitored.
  
  
  RESULTS
  At the last follow-up examination, 84.1% (37/44) of the patients in group A and 82.5% (33/40) of the patients in group B had a good outcome, and there were no significant differences between the two groups. Boh Methods led to significant improvements in disc height, and while PEEK+autograft produced a smaller loss in disc height, the difference was insignificant. The improvements in slippage and the fusion and complication rates between the two groups were similar.
  
  
  CONCLUSIONS
  There were no significant differences in the clinical outcomes or radiographic improvements of both fusion methods in the treatment of adult isthmic spondylolisthesis. An autograft excised from a complete posterior arch containing a facet joint for interbody fusion is effective and affordable for treating isthmic spondylolisthesis.
authors.affiliation: Department of Orthopedic Surgery, Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China. Electronic address: gangwang2003@yeah.net.
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.affiliation: Department of Orthopedic Surgery, Central Hospital of Zibo City, Zibo 255036, China.
authors.forename: Dunfu
authors.initials: D
authors.lastname: Han
authors.affiliation: Department of Orthopedic Surgery, Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China.
authors.forename: Zhenglin
authors.initials: Z
authors.lastname: Cao
authors.affiliation: Department of Orthopedic Surgery, Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China.
authors.forename: Honggang
authors.initials: H
authors.lastname: Guan
authors.affiliation: Department of Orthopedic Surgery, Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China.
authors.forename: Tianhang
authors.initials: T
authors.lastname: Xuan
mesh_terms: D000328:Adult; D000368:Aged; D064592:Autografts; D001577:Benzophenones; D016025:Bone Transplantation / Q000379:methods; D005260:Female; D006801:Humans; D007659:Ketones / Q000627:therapeutic use*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D011108:Polymers; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000379:methods; D013168:Spondylolisthesis / Q000188:drug therapy* / Q000601:surgery; D014182:Transplantation, Autologous / Q000379:methods; D016896:Treatment Outcome
chemical_list: D001577:Benzophenones; D007659:Ketones; D011108:Polymers; C063834:polyetheretherketone; D011092:Polyethylene Glycols
keywords: 3; Autograft; Isthmic spondylolisthesis; Local bone graft; PEEK cage; Posterior lumbar interbody fusion; Spinal fusion