title: Personality dimensions in schizophrenia: A family study.
abstract: Studies have demonstrated that personality traits differ in schizophrenia patients and family members compared to controls, suggesting familial risk. This study evaluated personality traits in a family study of schizophrenia, as well as the relationship between personality traits and symptoms and social functioning in schizophrenia patients. Thirty-two schizophrenia patients, 28 adult non-psychotic relatives, and 27 community controls completed the Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ). Schizophrenia patients differed on many dimensions of the DAPP-BQ compared to controls and/or relatives: affective lability, anxiousness, callousness, conduct problems, cognitive dysregulation, identity problem, intimacy, insecure attachment, low affiliation, narcissism, oppositionality, restricted expression, self-harm, submissiveness, and suspiciousness. No differences were found between relatives and controls. Furthermore, in schizophrenia patients, associations were found between personality and particularly general symptoms, as well as social functioning. Personality traits can be conceptualized as an extended phenotype in schizophrenia patients.
authors.affiliation: Departments of Psychology and Psychological Clinical Science, University of Toronto, Canada. Electronic address: vina.goghari@utoronto.ca.
authors.forename: Vina M
authors.initials: VM
authors.lastname: Goghari
mesh_terms: D000328:Adult; D001007:Anxiety / Q000235:genetics / Q000523:psychology; D005190:Family / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality / Q000235:genetics*; D010552:Personality Assessment / Q000592:standards; D010554:Personality Disorders / Q000235:genetics* / Q000523:psychology*; D012559:Schizophrenia / Q000235:genetics*; D012565:Schizophrenic Psychology; D011795:Surveys and Questionnaires
keywords: Genetic risk; Psychosis; Relatives; Social functioning; Vulnerability marker