title: Prevalence of Anemia in Subjects Randomized into Roux-en-Y Gastric Bypass or Sleeve Gastrectomy.
abstract: Although bariatric surgery fosters heightened excess weight loss values, nutritional deficiencies are prominent; one of the most common being iron deficiency anemia. The purpose is to elucidate the frequency of anemia in Roux-en-Y gastric bypass and sleeve gastrectomy subjects.
  
  
  
  A retrospective analysis was conducted, in subjects (N = 100) diagnosed with type II diabetes who were randomized into sleeve gastrectomy or Roux-en-Y gastric bypass and intensive medical therapy.
  
  
  
  Anemia was more common in female subjects who underwent sleeve gastrectomy-roughly half developed microcytosis at 24 months and thereafter.
  
  
  
  The etiology of anemia appears to be iron-related and precipitated by the female sex. Scant iron supplementation is likely causative. However, anemia of chronic inflammation cannot be discounted as being somewhat causal. Subsequently, the aggregate may have had a synergistic influence.
authors.affiliation: Department of Endocrinology and Metabolism, Cleveland Clinic, 9500 Euclid Avenue F20, Cleveland, OH, 44195, USA.
authors.forename: Karim G
authors.initials: KG
authors.lastname: Kheniser
authors.affiliation: Department of Endocrinology and Metabolism, Cleveland Clinic, 9500 Euclid Avenue F20, Cleveland, OH, 44195, USA. Kashyas@ccf.org.
authors.forename: Sangeeta R
authors.initials: SR
authors.lastname: Kashyap
authors.affiliation: Bariatric and Metabolic Institute, Metabolic Translational Research Center, Endocrine and Metabolism Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
authors.forename: Philip R
authors.initials: PR
authors.lastname: Schauer
authors.affiliation: Department of Health and Human Performance, Cleveland State University, 2121 Euclid Avenue, Cleveland, OH, 44115, USA.
authors.forename: Eddie T C
authors.initials: ETC
authors.lastname: Lam
authors.affiliation: Department of Health and Human Performance, Cleveland State University, 2121 Euclid Avenue, Cleveland, OH, 44115, USA.
authors.forename: Emily S
authors.initials: ES
authors.lastname: Kullman
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects / Q000706:statistics & numerical data; D015390:Gastric Bypass / Q000009:adverse effects / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D015995:Prevalence; D011897:Random Allocation; D012189:Retrospective Studies; D055815:Young Adult
keywords: Anemia of chronic inflammation; Iron deficiency anemia; Metabolic surgery; Nutritional deficiencies; Type II diabetes