title: An Improved Strategy for the Synthesis of Ethylene Glycol by Oxamate-Mediated Catalytic Hydrogenation.
abstract: The present study reports an improved approach for the preparation of ethylene glycol (EG) by using carbon monoxide as C1 chemical by a two-step oxidative carbonylation and hydrogenation sequence. In the first step, oxamates are synthesized through oxidative cross double carbonylation of piperidine and ethanol by using Pd/C catalyst under phosphine ligand-free conditions and subsequently hydrogenated by Milstein's catalyst (carbonylhydrido[6-(di-t-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine]ruthenium(II)). The presented stepwise oxamate-mediated coupling provides the basis for a new strategy for the synthesis of EG by selective upgrading of C1 chemicals.
authors.affiliation: Department of Chemistry, Institute of Chemical Technology, N.P. Marg, Matunga, Mumbai, 400019, India.|Reliance Industries Limited, Patalganga, Rasayani, Raigad, Maharashtra, 410 220, India.
authors.forename: Anilkumar
authors.initials: A
authors.lastname: Satapathy
authors.affiliation: Department of Chemistry, Institute of Chemical Technology, N.P. Marg, Matunga, Mumbai, 400019, India.
authors.forename: Sandip T
authors.initials: ST
authors.lastname: Gadge
authors.affiliation: Department of Chemistry, Institute of Chemical Technology, N.P. Marg, Matunga, Mumbai, 400019, India.
authors.forename: Bhalchandra M
authors.initials: BM
authors.lastname: Bhanage
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D019855:Ethylene Glycol / Q000138:chemical synthesis* / Q000737:chemistry*; D006865:Hydrogenation; D010072:Oxamic Acid / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
chemical_list: D010165:Palladium; D019855:Ethylene Glycol; D010072:Oxamic Acid
keywords: carbonylation; ethylene glycol; hydrogenation; oxamates; ruthenium