title: Long-term Clinical Efficacy and Safety Profile of Transurethral Resection of Prostate Versus Plasmakinetic Resection of the Prostate for Benign Prostatic Hyperplasia.
abstract: OBJECTIVE
  To investigate the differences on clinical efficacy, complications, and safety profile between transurethral resection of the prostate (TURP) and bipolar plasmakinetic resection of the prostate (PKRP) for benign prostatic hyperplasia (BPH).
  
  
  METHODS
  Six hundred ninety patients of BPH were recruited from May 2008 to May 2011 and divided into TURP group and PKRP group. The International Prostate Symptom Score (IPSS), quality of life score (QoL), postvoid residual urine (PVR), maximum flow rate (Qmax), complications, International Index of Erectile Function-5 (IIEF-5) questionnaire, and retrograde ejaculation were used for evaluation of clinical efficacy and safety and sexual function between the 2 groups.
  
  
  RESULTS
  The intraoperative irrigation volume, postoperative irrigation volume, postoperative irrigation time, decrease in sodium, intraoperative blood loss, and duration of catheterization of the PKRP group were significantly lower than those of the TURP group (P <.05). For comparison of complications, the incidence rates of massive hemorrhage, blood transfusion, capsular perforation, prolonged hematuria, micturition frequency, micturition urgency, and micturition pain of the PKRP group were significantly less than those of the TURP group (P <.05). During the 5-year follow-up, the PKRP group showed better effect on IPSS, QoL, PVR, and Qmaxcompared with the TURP group (P <.05), but there were no significant differences on IIEF-5 and retrograde ejaculation (P > .05).
  
  
  CONCLUSIONS
  PKRP is just as efficacious as TURP and is associated with a lower rate of certain morbidities. Its lower complications and better safety profile make PKRP an attractive alternative for treatment of BPH.
authors.affiliation: Department of Urology, Hunan Provincial People's Hospital, Changsha, Hunan Province, China. Electronic address: 18974898411@189.cn.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Urology, Hunan Provincial People's Hospital, Changsha, Hunan Province, China.
authors.forename: Yuan Wei
authors.initials: YW
authors.lastname: Li
authors.affiliation: Department of Urology, Hunan Provincial People's Hospital, Changsha, Hunan Province, China.
authors.forename: Wan Rui
authors.initials: WR
authors.lastname: Wu
authors.affiliation: Department of Urology, Hunan Provincial People's Hospital, Changsha, Hunan Province, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Lu
mesh_terms: D000368:Aged; D057908:Argon Plasma Coagulation / Q000009:adverse effects / Q000379:methods; D002681:China; D057186:Comparative Effectiveness Research; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D011467:Prostate / Q000473:pathology / Q000601:surgery*; D011470:Prostatic Hyperplasia / Q000473:pathology / Q000601:surgery*; D011788:Quality of Life; D012086:Reoperation; D012189:Retrospective Studies; D012735:Sexual Dysfunction, Physiological / Q000209:etiology; D020728:Transurethral Resection of Prostate / Q000009:adverse effects / Q000379:methods; D016896:Treatment Outcome