title: Hospital wide porcine mesh conversion results in cost savings with equivalent clinical outcomes.
abstract: BACKGROUND
  A variety of biologic mesh is available for ventral hernia repair. Despite widely variable costs, there is no data comparing cost of material to clinical outcome.
  
  
  METHODS
  Biologic mesh product change was examined. A prospective survey was done to determine appropriate biologic mesh utilization, followed by a retrospective chart review of those treated from Sept. 2012 to Aug. 2013 with Strattice™ and from Sept. 2013 to Aug. 2014 with Permacol™. Outcome variables included complications associated with each material, repair success, and cost difference over the two periods.
  
  
  RESULTS
  28 patients received Strattice™ and 41 Permacol™. There was no statistical difference in patient factors, hernia characteristics, length of stay, readmission rates or surgical site infections at 30 days. The charges were significantly higher for Strattice™ with the median cost $8940 compared to $1600 for Permacol™ (p < 0.001). Permacol™ use resulted in a savings if $181,320.
  
  
  CONCLUSIONS
  Permacol™ use resulted in similar clinical outcomes with significant cost savings when compared to Strattice™. Biologic mesh choice should be driven by a combination of clinical outcomes and product cost.
authors.affiliation: Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.
authors.forename: Nickolas
authors.initials: N
authors.lastname: Byrge
authors.affiliation: Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.
authors.forename: Mary C
authors.initials: MC
authors.lastname: Mone
authors.affiliation: Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: daniel.vargo@hsc.utah.edu.
authors.forename: Daniel
authors.initials: D
authors.lastname: Vargo
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003094:Collagen / Q000191:economics* / Q000627:therapeutic use; D017046:Cost Savings; D005260:Female; D006555:Hernia, Ventral / Q000191:economics / Q000601:surgery*; D059685:Herniorrhaphy / Q000191:economics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013526:Surgical Mesh / Q000191:economics*; D016896:Treatment Outcome
chemical_list: C422414:Permacol; C568444:strattice; D003094:Collagen
keywords: Biologic mesh; Cost; Permacol™; Strattice™; Ventral hernia