title: Clinical Features and Management of Subretinal Abscesses Secondary to Methicillin-Resistant Staphylococcus aureus Endogenous Endophthalmitis.
abstract: To describe the clinical features, management, and immediate outcomes of patients with subretinal abscesses secondary to methicillin-resistant Staphylococcus aureus (MRSA) endogenous endophthalmitis.
  
  
  
  Eleven eyes of seven patients were identified by retrospective chart review. Demographics, initial presentation, examination findings, imaging, cultures, treatments, and short-term outcomes were reviewed.
  
  
  
  Eleven eyes of seven patients presented with subretinal abscesses secondary to MRSA endogenous endophthalmitis. Four had history of recurrent MRSA infections or active soft-tissue ulceration. Six underwent vitreous tap for culture without growth. Three had positive blood cultures for MRSA. Six received empiric therapy with intravenous vancomycin, one received oral trimethoprim-sulfamethoxazole, and six received intravitreal vancomycin. Consolidation of abscesses was seen within days of initial treatment. Visual outcomes were contingent on abscess location and time to initial treatment.
  
  
  
  Prompt diagnosis and systemic antibiotic therapy is paramount in the treatment of this rare presentation. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:134-142.].
authors.forename: Jorge
authors.initials: J
authors.lastname: Fortun
authors.forename: Yasha S
authors.initials: YS
authors.lastname: Modi
authors.forename: Angela
authors.initials: A
authors.lastname: Bessette
authors.forename: Jordan
authors.initials: J
authors.lastname: Heffez
authors.forename: Petros
authors.initials: P
authors.lastname: Carvounis
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Petkovsek
authors.forename: Nicholas G
authors.initials: NG
authors.lastname: Anderson
authors.forename: Daniel
authors.initials: D
authors.lastname: Martin
authors.forename: Sunil
authors.initials: S
authors.lastname: Srivastava
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019468:Disease Management; D009877:Endophthalmitis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D041623:Tomography, Optical Coherence; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents