title: Hyperspectral infrared nanoimaging of organic samples based on Fourier transform infrared nanospectroscopy.
abstract: Infrared nanospectroscopy enables novel possibilities for chemical and structural analysis of nanocomposites, biomaterials or optoelectronic devices. Here we introduce hyperspectral infrared nanoimaging based on Fourier transform infrared nanospectroscopy with a tunable bandwidth-limited laser continuum. We describe the technical implementations and present hyperspectral infrared near-field images of about 5,000 pixel, each one covering the spectral range from 1,000 to 1,900 cm-1. To verify the technique and to demonstrate its application potential, we imaged a three-component polymer blend and a melanin granule in a human hair cross-section, and demonstrate that multivariate data analysis can be applied for extracting spatially resolved chemical information. Particularly, we demonstrate that distribution and chemical interaction between the polymer components can be mapped with a spatial resolution of about 30 nm. We foresee wide application potential of hyperspectral infrared nanoimaging for valuable chemical materials characterization and quality control in various fields ranging from materials sciences to biomedicine.
authors.affiliation: CIC nanoGUNE, 20018 Donostia-San Sebastián, Spain.
authors.forename: Iban
authors.initials: I
authors.lastname: Amenabar
authors.affiliation: CIC nanoGUNE, 20018 Donostia-San Sebastián, Spain.|IFIB - Interfaculty Institute of Biochemistry, 72076 Tübingen, Germany.
authors.forename: Simon
authors.initials: S
authors.lastname: Poly
authors.affiliation: CIC nanoGUNE, 20018 Donostia-San Sebastián, Spain.|Metallic Surfaces Unit, IK4-CIDETEC, 20014 Donostia-San Sebastián, Spain.
authors.forename: Monika
authors.initials: M
authors.lastname: Goikoetxea
authors.affiliation: CIC nanoGUNE, 20018 Donostia-San Sebastián, Spain.
authors.forename: Wiwat
authors.initials: W
authors.lastname: Nuansing
authors.affiliation: Department of Proteomics and Spectroscopy (ZBS6), Robert Koch Institut, 13353 Berlin, Germany.
authors.forename: Peter
authors.identifier: 0000-0001-6193-3144
authors.initials: P
authors.lastname: Lasch
authors.affiliation: CIC NanoGUNE and UPV/EHU, 20018 Donostia-San Sebastián, Spain.|IKERBASQUE, Basque Foundation for Science, 48013 Bilbao, Spain.
authors.forename: Rainer
authors.initials: R
authors.lastname: Hillenbrand