title: The Ivy Sign on Fluid Attenuated Inversion Recovery Images Related to Single-Photon Emission Computed Tomography Cerebral Blood Flow in Moyamoya Disease: A Case Report.
abstract: Moyamoya disease is an idiopathic progressive cerebrovascular steno-occlusive disorder characterized by the formation of numerous collaterals called Moyamoya vessels. Accurate evaluation of vascular status and cerebral blood flow (CBF) is needed for prompt treatment to prevent ischemic and/or hemorrhagic events. The pathogenesis of the ivy sign on fluid attenuated inversion recovery (FLAIR) images of Moyamoya disease patients is unclear. We report a Moyamoya disease case wherein the ivy sign changed in relation to single-photon emission computed tomography (SPECT)-measured CBF during progression and following treatment. A 49-year-old female presented with slight aphasia and right hemiparesis. Magnetic resonance imaging (MRI) diffusionweighted image revealed cerebral infarction in the left frontal lobe. Cerebral angiography images showed bilateral distal internal carotid artery stenosis and Moyamoya vessels. FLAIR images exhibited the ivy sign. We performed superficial temporal arteryâ€" middle cerebral artery (STA-MCA) bypass surgery with encephalogaleosynangiosis (EGS) and encephalomyosynangiosis (EMS) on the left side 6 months after first presentation. After operation, left-side resting CBF gradually improved on SPECT and the ivy sign decreased. On the other hand, right-side CBF gradually deteriorated at rest, and the ivy sign increased. Therefore, we performed STAâˆ'MCA bypass with EGS and EMS on the right side 4 years after first presentation. After the operation, the resting CBF increased and the ivy sign decreased. The FLAIR ivy sign may be a useful indicator of both deterioration and improvement of CBF status without the need for CBF imaging using contrast material.
authors.affiliation: Chiba Hokusou Hospital, Department of Neurosurgery, Chiba, Japan.
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Matano
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Murai
authors.forename: Asami
authors.initials: A
authors.lastname: Kubota
authors.forename: Takayuki
authors.initials: T
authors.lastname: Mizunari
authors.forename: Shiro
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Akio
authors.initials: A
authors.lastname: Morita
mesh_terms: D016893:Carotid Stenosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D002533:Cerebral Angiography / Q000379:methods; D002544:Cerebral Infarction / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D002548:Cerebral Revascularization / Q000379:methods*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging / Q000601:surgery; D009072:Moyamoya Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*