title: Cobalt-Catalyzed α-Alkylation of Ketones with Primary Alcohols.
abstract: An ionic cobalt-PNP complex is developed for the efficient α-alkylation of ketones with primary alcohols for the first time. A broad range of ketone and alcohol substrates were employed, leading to the isolation of alkylated ketones with yields up to 98%. The method was successfully applied to the greener synthesis of quinoline derivatives while using 2-aminobenzyl alcohol as an alkylating reagent.
authors.affiliation: Department of Sciences, John Jay College and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York , New York, New York 10019, United States.
authors.forename: Guoqi
authors.identifier: 0000-0001-6071-8469
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Department of Sciences, John Jay College and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York , New York, New York 10019, United States.|Department of Chemistry, Hunter College, the City University of New York , New York, New York 10065, United States.
authors.forename: Jing
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Sciences, John Jay College and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York , New York, New York 10019, United States.|Department of Chemistry, Hunter College, the City University of New York , New York, New York 10065, United States.
authors.forename: Haisu
authors.initials: H
authors.lastname: Zeng
authors.affiliation: Department of Sciences, John Jay College and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York , New York, New York 10019, United States.
authors.forename: Shu
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Sciences, John Jay College and Ph.D. Program in Chemistry, The Graduate Center of the City University of New York , New York, New York 10019, United States.|Department of Chemistry, Hunter College, the City University of New York , New York, New York 10065, United States.
authors.forename: Zhiwei
authors.identifier: 0000-0002-4545-1783
authors.initials: Z
authors.lastname: Yin
authors.affiliation: Department of Chemistry, Hunter College, the City University of New York , New York, New York 10065, United States.
authors.forename: Shengping
authors.initials: S
authors.lastname: Zheng