title: Changes in allele frequencies ofCSF3RandSETBP1mutations and evidence of clonal evolution in a chronic neutrophilic leukemia patient treated with ruxolitinib.
authors.affiliation: University of Colorado Division of Hematology, Aurora, CO, USA.
authors.forename: Zohra
authors.initials: Z
authors.lastname: Nooruddin
authors.affiliation: Children's Hospital of Colorado, Department of Pathology, Aurora, CO, USA.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Miltgen
authors.affiliation: Children's Hospital of Colorado, Department of Pathology, Aurora, CO, USA.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wei
authors.affiliation: University of Colorado Department of Pathology, Aurora, CO, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Schowinsky
authors.affiliation: University of Colorado Department of Pathology, Aurora, CO, USA.
authors.forename: Zengang
authors.initials: Z
authors.lastname: Pan
authors.affiliation: University of Colorado School of Pharmacy, Aurora, CO, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Tobin
authors.affiliation: University of Colorado Division of Hematology, Aurora, CO, USA.
authors.forename: Enkhtsetseg
authors.initials: E
authors.lastname: Purev
authors.affiliation: University of Colorado Division of Hematology, Aurora, CO, USA.
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Gutman
authors.affiliation: University of Colorado Division of Hematology, Aurora, CO, USA.
authors.forename: William
authors.initials: W
authors.lastname: Robinson
authors.affiliation: University of Colorado Division of Hematology, Aurora, CO, USA daniel.pollyea@ucdenver.edu.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Pollyea
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D002352:Carrier Proteins / Q000235:genetics*; D060965:Clonal Evolution / Q000187:drug effects / Q000235:genetics*; D018450:Disease Progression; D005787:Gene Frequency; D006801:Humans; D015467:Leukemia, Neutrophilic, Chronic / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D007958:Leukocyte Count; D009154:Mutation; D009570:Nitriles; D009687:Nuclear Proteins / Q000235:genetics*; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011720:Pyrazoles / Q000494:pharmacology / Q000627:therapeutic use*; D011743:Pyrimidines; D016184:Receptors, Colony-Stimulating Factor / Q000235:genetics*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; C517047:CSF3R protein, human; D002352:Carrier Proteins; D009570:Nitriles; D009687:Nuclear Proteins; D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D011743:Pyrimidines; D016184:Receptors, Colony-Stimulating Factor; C425066:SETBP1 protein, human; C540383:ruxolitinib