title: Endoscopic Ultrasound-Guided Drainage of Intra-Abdominal Abscess after Gastric Perforation in a Patient Receiving Ramucirumab and Paclitaxel for Advanced Gastric Cancer.
abstract: Gastrointestinal perforation is a serious adverse event that occurs in approximately 1% of patients receiving ramucirumab and paclitaxel. A 67-year-old man with unresectable advanced gastric cancer was admitted to our hospital and treated with ramucirumab and paclitaxel. Gastric perforation occurred during the second cycle of chemotherapy. Although the patient's condition improved without surgery, an abscess developed in the intra-abdominal fluid collection resulting from the perforation. We performed endoscopic ultrasound-guided abscess drainage. The patient improved and was discharged in satisfactory condition. Endoscopic ultrasound-guided drainage is a treatment option for patients with intra-abdominal abscess following gastric perforation due to ramucirumab.
authors.affiliation: Department of Gastroenterology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Mandai
authors.affiliation: Department of Gastroenterology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shirakawa
authors.affiliation: Department of Gastroenterology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Uno
authors.affiliation: Department of Gastroenterology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Yasuda
keywords: Advanced gastric cancer; Endoscopic ultrasound-guided drainage; Gastric perforation; Intra-abdominal abscess; Ramucirumab