title: Spontaneous Rupture of the Main Pancreatic Duct Synchronous With a Multi-Focal Microscopic Pancreatic Adenocarcinoma: A Case Report.
abstract: Pancreatic cancer is one of the most lethal types of malignant tumours, commonly diagnosed at an advanced stage. The only curative treatment for this fatal disease is surgery and early diagnosis is the key to a better outcome and prognosis. In this case report we present a 57-year-old woman presenting to the emergency room with abdominal pain and weight loss. Computer Tomography (CT) imaging showed a rupture of the main pancreatic duct and a peri-pancreatic fluid collection with no evidence of a pancreatic mass. An Endoscopic Ultrasound (EUS) guided Fine Needle Aspiration (FNA) did not show any malignant cells and Carcinoembryonic Antigen (CEA) and Carbohydrate Antigen (CA) 19-9 markers were in the normal range. The patient then underwent pancreatectomy that revealed multiple microscopic foci of pancreatic adenocarcinoma with evidence of massive perineural and vascular invasion.
authors.affiliation: Faculty, Surgery Division, Hillel Yaffe Medical Center , Hadera, Israel .
authors.forename: Shirly
authors.initials: S
authors.lastname: Shohat
authors.affiliation: Faculty, Oncology Unit, Hillel Yaffe Medical Center , Hadera, Israel .
authors.forename: Katerina
authors.initials: K
authors.lastname: Shulman
authors.affiliation: Faculty, Surgery Division, Hillel Yaffe Medical Center , Hadera, Israel .
authors.forename: Boris
authors.initials: B
authors.lastname: Kessel
authors.affiliation: Faculty, Gastroenterology Department, Hillel Yaffe Medical Center , Hadera, Israel .
authors.forename: Oren
authors.initials: O
authors.lastname: Gal
authors.affiliation: Faculty, Radiology Department, Hillel Yaffe Medical Center , Hadera, Israel .
authors.forename: Abdel Rauf
authors.initials: AR
authors.lastname: Zeina
keywords: Early detection; Pancreatectomy; Pancreatic cancer; Wirsung rupture