title: The Use of Recombinant Human Platelet-Derived Growth Factor for Maxillary Sinus Augmentation.
abstract: The maxillary sinus augmentation procedure has become a predictable treatment to regenerate bone for implant placement. The purpose of this study was to evaluate the effect of recombinant human platelet-derived growth factor BB (rhPDGF-BB) combined with a deproteinized cancellous bovine bone graft for sinus augmentation. The lateral window approach was used for maxillary sinuses with minimal residual bone. After a healing period of 4 months, dental implants were placed and then restored following a 2-month osseointegration period. The result demonstrated increased bone height and ISQ values and a 100% survival rate. This study indicates that the addition of rhPDGF-BB to deproteinized cancellous bovine bone accelerated the healing period in maxillary sinuses with minimal native bone.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kubota
authors.forename: Hector
authors.initials: H
authors.lastname: Sarmiento
authors.forename: Mohammed Saad
authors.initials: MS
authors.lastname: Alqahtani
authors.forename: Arturo
authors.initials: A
authors.lastname: Llobell
authors.forename: Joseph P
authors.initials: JP
authors.lastname: Fiorellini
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000077214:Becaplermin; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods; D002417:Cattle; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D005260:Female; D006801:Humans; D008297:Male; D008437:Maxilla / Q000000981:diagnostic imaging / Q000601:surgery*; D008443:Maxillary Sinus / Q000000981:diagnostic imaging / Q000601:surgery*; D008567:Membranes, Artificial; D008875:Middle Aged; D008903:Minerals / Q000627:therapeutic use; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods; D016348:Osseointegration; D010027:Osteotomy; D020574:Proto-Oncogene Proteins c-sis / Q000627:therapeutic use*; D059546:Sinus Floor Augmentation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: C077540:Bio-Oss; D015921:Dental Implants; D008567:Membranes, Artificial; D008903:Minerals; D020574:Proto-Oncogene Proteins c-sis; D000077214:Becaplermin