title: The prospective opportunities offered by magnetic scaffolds for bone tissue engineering: a review.
abstract: Magnetic scaffolds are becoming increasingly attractive in tissue engineering, due to their ability to enhance bone tissue formation by attracting soluble factors, such as growth factors, hormones and polypeptides, directly to the implantation site, as well as their potential to improve the fixation and stability of the implant. Moreover, there is increasing evidence that the synergistic effects of magnetic scaffolds and magnetic fields can promote bone repair and regeneration. In this manuscript we review the recent innovations in bone tissue engineering that exploit magnetic biomaterials combined with static magnetic fields to enhance bone cell adhesion and proliferation, and thus bone tissue growth.
authors.affiliation: Laboratory of Nano Biotechnology (NaBi), Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Ortolani
authors.affiliation: Laboratory of Nano Biotechnology (NaBi), Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Bianchi
authors.affiliation: I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Mosca
authors.affiliation: I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Silvio
authors.initials: S
authors.lastname: Caravelli
authors.affiliation: I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Fuiano
authors.affiliation: Laboratory of Nano Biotechnology (NaBi), Istituto Ortopedico Rizzoli, Bologna, Italy; I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Maurilio
authors.initials: M
authors.lastname: Marcacci
authors.affiliation: Laboratory of Nano Biotechnology (NaBi), Istituto Ortopedico Rizzoli, Bologna, Italy; I Orthopaedic and Traumatological Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Russo
keywords: bone; magnetic; regeneration; scaffold; tissue engineering