title: Ruxolitinib rechallenge in combination with hydroxyurea is effective in reverting cachexia and reducing blood transfusion demand and splenomegaly symptoms in a patient with primary myelofibrosis.
authors.affiliation: Hematology Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131, Naples, Italy. claudiocerc@hotmail.com.
authors.forename: Claudio
authors.initials: C
authors.lastname: Cerchione
authors.affiliation: Hematology Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131, Naples, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Peluso
authors.affiliation: Hematology Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131, Naples, Italy.
authors.forename: Davide
authors.initials: D
authors.lastname: Nappi
authors.affiliation: Hematology Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131, Naples, Italy.
authors.forename: Anna Emanuele
authors.initials: AE
authors.lastname: Pareto
authors.affiliation: Hematology Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131, Naples, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Picardi
authors.affiliation: Hematology Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131, Naples, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Martinelli
authors.affiliation: Hematology Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131, Naples, Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Pane
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001803:Blood Transfusion; D002100:Cachexia / Q000209:etiology / Q000517:prevention & control*; D004334:Drug Administration Schedule; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009570:Nitriles; D055728:Primary Myelofibrosis / Q000150:complications / Q000188:drug therapy*; D011720:Pyrazoles / Q000008:administration & dosage*; D011743:Pyrimidines; D013163:Splenomegaly / Q000188:drug therapy* / Q000209:etiology
chemical_list: D009570:Nitriles; D011720:Pyrazoles; D011743:Pyrimidines; C540383:ruxolitinib; D006918:Hydroxyurea
keywords: Cachexia; Hydroxyurea; Primary myelofibrosis; Ruxolitinib; Splenomegaly