title: Continuous Positive Airway Pressure Adherence In Patients with Obstructive Sleep Apnea & Symptomatic BPH.
abstract: Purpose To determine the short-term and long-term adherence rates with continuous positive airway pressure (CPAP) therapy in sleep apnea patients with benign prostatic hyperplasia (BPH) compared to matched controls. Methods A case-control retrospective analysis was performed in a veterans affairs hospital. All symptomatic patients with BPH (n = 107) ever started on CPAP therapy between 2006 and 2012 were compared with controls matched for severity of sleep apnea (AHI). Adherence measures were obtained at the third and twelfth month visits. The cases included symptomatic BPH patients on active medical therapy. Diuretic use among cases and controls, and severity of nocturia among the cases were also analyzed. Results The mean AHI among cases and controls was 35.6 ± 27.3 and 35.5 ± 31 (p = 0.96). The population was male and predominantly Caucasian. There was no statistically significant difference in percent days CPAP device use ≥4 h. between symptomatic BPH patients and controls at 3-month (51.6 ± 38 vs. 47.2 ± 36; p = 0.43) and 1-year (64 ± 40.5 vs. 64.7 ± 31.3; p = 0.90) visits. The use of diuretics in the cases and controls, and the severity of nocturia in the cases did not influence adherence with CPAP therapy. Conclusions BPH or diuretic use did not affect adherence with CPAP therapy in obstructive sleep apnea. Severity of nocturia did not have any influence on adherence among the cases. BPH, regardless of the severity of nocturia, and diuretic use does not influence CPAP adherence in patients with OSA.
authors.affiliation: The Veterans Affairs Western New York Healthcare System, University at Buffalo, 3495 Bailey Avenue, Buffalo, NY, 14215, USA. dr.rameshmetta@gmail.com.|Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, 3495 Bailey Avenue, Buffalo, NY, 14215, USA. dr.rameshmetta@gmail.com.
authors.forename: Ramesh V V S
authors.initials: RV
authors.lastname: Metta
authors.affiliation: Department of Medicine, University at Buffalo, Buffalo, NY, USA.
authors.forename: Awais
authors.initials: A
authors.lastname: Zaka
authors.affiliation: Department of Medicine, University at Buffalo, Buffalo, NY, USA.
authors.forename: Vincent C
authors.initials: VC
authors.lastname: Lee
authors.affiliation: The Veterans Affairs Western New York Healthcare System, University at Buffalo, 3495 Bailey Avenue, Buffalo, NY, 14215, USA.|Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, 3495 Bailey Avenue, Buffalo, NY, 14215, USA.
authors.forename: M Jeffery
authors.initials: MJ
authors.lastname: Mador
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D045422:Continuous Positive Airway Pressure; D004232:Diuretics / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000209:etiology*; D010349:Patient Compliance / Q000706:statistics & numerical data*; D011470:Prostatic Hyperplasia / Q000150:complications* / Q000188:drug therapy; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000628:therapy*
chemical_list: D004232:Diuretics
keywords: BPH; Benign prostatic hyperplasia; CPAP adherence; Nocturia; Positive airway pressure; Sleep apnea