title: Familial Restless Legs Syndrome: A Family with all Female Patients.
abstract: BACKGROUND
  Restless legs syndrome (RLS) is a chronic condition characterized by odd sensations in the body, most commonly in the legs and an irresistible urge to move them. More than half of the patients with RLS have a family history. Most of the RLS cases are women and most of the families show characteristics of an autosomal dominant pedigree. Here, we shall present a family consisting only of women; to our knowledge, such a family has not been reported yet.
  
  
  METHODS
  The family presented here met the diagnosis criteria specified by International Restless Legs Syndrome Study Group (IRLSS). Clinical characteristic are described along with demographic properties.
  
  
  RESULTS
  The patients were between 12 and 59 years of age with a mean age of 35.3 ± 14.4 years. All 7 cases were women. The pedigree of the patients exhibited an autosomal dominant inheritance pattern.
  
  
  CONCLUSIONS
  The present family tree indicates that familial RLS can exhibit a heredity pattern which shows autosomal dominant inheritance. The present family is still under follow-up. Future research is required to support the present data.
authors.affiliation: Training and Research Hospital, Neurology Clinic, Samsun, Turkey.
authors.forename: Cetin Kursad
authors.initials: CK
authors.lastname: Akpinar
authors.affiliation: Ondokuz Mayis University, Medical Faculty, Department of Neurology, Samsun, Turkey.
authors.forename: Hande
authors.initials: H
authors.lastname: Turker
authors.affiliation: Ondokuz Mayis University, Medical Faculty, Department of Neurology, Samsun, Turkey.
authors.forename: Dursun
authors.initials: D
authors.lastname: Aygun
authors.affiliation: Firat University, Medical Faculty, Department of Neurology, Elazig, Turkey.
authors.forename: Emrah
authors.initials: E
authors.lastname: Aytac
mesh_terms: D000293:Adolescent; D000328:Adult; D000369:Aged, 80 and over; D018798:Anemia, Iron-Deficiency / Q000175:diagnosis*; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D040582:Inheritance Patterns; D008875:Middle Aged; D010375:Pedigree; D012148:Restless Legs Syndrome / Q000150:complications*; D014421:Turkey; D055815:Young Adult
chemical_list: D005293:Ferritins