title: Synthesis of Enantiopure C3-Symmetric Triangular Molecules.
abstract: An asymmetric synthesis of C3-symmetric triangular macrocycles is reported. 1-Methylsulfonyl-4-(4-vinylphenyl)-1,2,3-triazole undergoes a rhodium(II)-catalyzed cyclotrimerization to establish an enantiopure C3-symmetric triangular macrocycle motif. This method can be applied to the synthesis of an enantiopure hydrocarbon, which owes its chirality to asymmetric distribution of H/D atoms on the benzene rings.
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.
authors.forename: Tomoya
authors.identifier: 0000-0003-2493-0184
authors.initials: T
authors.lastname: Miura
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nakamuro
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.|School of Chemistry and Biochemistry, The University of Western Australia, Australia.
authors.forename: Scott G
authors.initials: SG
authors.lastname: Stewart
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.
authors.forename: Yuuya
authors.initials: Y
authors.lastname: Nagata
authors.affiliation: Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto, 615-8510, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami
keywords: C3-symmetry; asymmetric synthesis; cyclotrimerization; macrocycles; rhodium