title: Pregenual Anterior Cingulate Gyrus Involvement in Spontaneous Social Interactions in Primates-Evidence from Behavioral, Pharmacological, Neuropsychiatric, and Neurophysiological Findings.
abstract: The anterior cingulate cortex (ACC) has been implicated in different aspects of cognition and decision making, including social cognition. Several studies suggest that this region is actually formed by sub-regions concerned with distinct cognitive functions. The ACC is usually divided in its rostro-caudal axis, with the caudal ACC playing a major role in processing own actions, and the rostral ACC being related to social cognition. Recently, it has been suggested that the ACC can also be functionally divided in its dorso-ventral axis into ACC gyrus (ACCg) and ACC sulcus (ACCs), with the ACCg having a central role in processing social information. In this context, we propose that the pregenual ACCg might be especially important for engaging in social interactions. We discuss previous findings that support this hypothesis and present evidence suggesting that the activity of pregenual ACCg neurons is modulated during spontaneous social interactions.
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of Toyama Toyama, Japan.
authors.forename: Can Van
authors.initials: CV
authors.lastname: Mao
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of ToyamaToyama, Japan; Edmond and Lily Safra International Institute of Neuroscience, Santos Dumont InstituteMacaiba, Brazil.
authors.forename: Mariana F P
authors.initials: MF
authors.lastname: Araujo
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of Toyama Toyama, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nishimaru
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of Toyama Toyama, Japan.
authors.forename: Jumpei
authors.initials: J
authors.lastname: Matsumoto
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of Toyama Toyama, Japan.
authors.forename: Ahn Hai
authors.initials: AH
authors.lastname: Tran
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of Toyama Toyama, Japan.
authors.forename: Etsuro
authors.initials: E
authors.lastname: Hori
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of Toyama Toyama, Japan.
authors.forename: Taketoshi
authors.initials: T
authors.lastname: Ono
authors.affiliation: System Emotional Science, Graduate School of Medicine, University of Toyama Toyama, Japan.
authors.forename: Hisao
authors.initials: H
authors.lastname: Nishijo
keywords: anterior cingulate cortex; freely behaving monkeys; single neuron activity; social cognition; social interactions