title: Crystal structure of (1R,3aR,7aR)-1-{(S)-1-[(2R,5S)-5-(3-hy-droxy-pentan-3-yl)tetra-hydro-furan-2-yl]eth-yl}-7a-methyl-2,3,3a,4,5,6,7,7a-octa-hydro-1H-inden-4-one.
abstract: The title compound, C21H36O3, contains an oxolane ring, and six defined stereocentres and may serve as a useful synthon for the synthesis of calcitriol analogues. The configurations of the chiral C atoms of the side chain were unambiguously established in the refinement. In the crystal, C-H⋯O and extremely weak O-H⋯O hydrogen bonds arising from the sterically hindered alcohol group link the mol-ecules into a three-dimensional network.
authors.affiliation: Dipartamento Química Orgínica, Facultade de Química, Universidade de Vigo, E-36310, Vigo, Spain.
authors.forename: Andrea
authors.initials: A
authors.lastname: Martínez
authors.affiliation: Dipartamento Química Orgínica, Facultade de Química, Universidade de Vigo, E-36310, Vigo, Spain.
authors.forename: Hugo
authors.initials: H
authors.lastname: Santalla
authors.affiliation: Dipartamento Química Orgínica, Facultade de Química, Universidade de Vigo, E-36310, Vigo, Spain.
authors.forename: Fátima
authors.initials: F
authors.lastname: Garrido
authors.affiliation: Département de Chimie, Faculté des Sciences, Université de Nouakchott, Nouakchott, Mauritania.
authors.forename: Aliou Hamady
authors.initials: AH
authors.lastname: Barry
authors.affiliation: Département de Chimie, Faculté des Sciences et Techniques, Université Cheikh Anta Diop, Dakar, Senegal.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Gaye
authors.affiliation: Dipartamento Química Orgínica, Facultade de Química, Universidade de Vigo, E-36310, Vigo, Spain.
authors.forename: Yagamare
authors.initials: Y
authors.lastname: Fall Diop
keywords: calcitriol; crystal structure; hydrogen bonding; vitamin D