title: Caffeoylquinic Acids from the Aerial Parts of Chrysanthemum coronarium L.
abstract: To elucidate the chemical compositions of the aerial parts ofChrysanthemum coronariumL., the ethanol extracts ofCh. coronariumL. were firstly isolated by the MCI-gel resin column. The caffeoylquinic acid-rich fractions were further purified by various chromatographic columns including silica gel, Sephadex LH-20, and semi-preparative HPLC to yield the compounds. The purified compounds were characterized by ¹H-Nuclear Magnetic Resonance (¹H-NMR),13C-NMR, and high resolution electrospray ionisation mass spectral (HR-ESI-MS) spectroscopy. Seven caffeoylquinic acid (CQA) compounds were isolated from this plant. Their structures were clarified by spectrometric methods and identified as 3-O-caffeoylquinic acid (1), 5-O-caffeoylquinic acid (2), 4-O-caffeoylquinic acid (3), 3,4-di-O-caffeoylquinic acid (4), 1,5-di-O-caffeoylquinic acid (5), 3,5-di-O-caffeoylquinic acid (6), and 4,5-di-O-caffeoylquinic acid (7). Caffeoylquinic acids were the major constituents present in the aerial parts ofCh. coronariumL. All of the isolates except for compounds2and6were reported for the first time from this species. Moreover, compounds3-5, and7were identified from theChrysanthemumgenus for the first time.
authors.affiliation: College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China. lemonwan@126.com.|Collaborative Innovation Center of Post-Harvest Key Technology and Quality Safety of Fruits and Vegetables in Jiangxi Province, Jiangxi Agricultural University, Nanchang 330045, China. lemonwan@126.com.
authors.forename: Chunpeng
authors.initials: C
authors.lastname: Wan
authors.affiliation: College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China. liss0824@126.com.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Li
authors.affiliation: College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China. linliu0960@126.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Liu
authors.affiliation: College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China. ccy0728@126.com.|Collaborative Innovation Center of Post-Harvest Key Technology and Quality Safety of Fruits and Vegetables in Jiangxi Province, Jiangxi Agricultural University, Nanchang 330045, China. ccy0728@126.com.
authors.forename: Chuying
authors.initials: C
authors.lastname: Chen
authors.affiliation: College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China. chunpengwan@jxau.edu.cn.
authors.forename: Shuying
authors.initials: S
authors.lastname: Fan
keywords: Chrysanthemum coronarium L.; aerial parts; caffeoylquinic acids