title: Undermining plastic surgery as a possible option for treating basal cell carcinoma of the forehead.
abstract: Basal cell carcinoma (BCC) is the most common cutaneous cancer. Although most cases can be cured with simple surgical procedures and are associated with a good prognosis, a minority of BCCs may pose significant therapeutic challenges. This occurs mostly in cases of so-called advanced BCC, which a loosely defined term that encompasses locally advanced lesions and tumors with metastatic spread. Treatment of these cases is often complex and sometimes may need combinations of therapeutic modalities, including surgery, radiotherapy and/or targeted therapy directed towards sonic hedgehog (SHH) signaling pathways, such as vismodegib. We herein present the case of a 74-year-old man presenting with a large basal cell of the forehead evolving for more than 7 years. The patient underwent excision of the lesion with clear surgical margins. Reconstruction of the defect was performed after extensive undermining of the skin allowing subsequent direct closure with a simple suture, which resulted in an acceptable cosmetic outcome. We discuss the potential advantages, disadvantages, and applicability of this relatively simple surgical maneuver in the reconstruction of defects resulting from excision of considerably large cutaneous tumors.
authors.affiliation: Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), Sofia, Bulgaria. georgi_tchernev@yahoo.de.|Onkoderma - Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria. georgi_tchernev@yahoo.de.
authors.forename: Georgi
authors.initials: G
authors.lastname: Tchernev
authors.affiliation: Department of General, Vascular and Abdominal Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), Generel Skobelev 79, 1606, Sofia, Bulgaria.
authors.forename: Ivan
authors.initials: I
authors.lastname: Pidakev
authors.affiliation: Department of General, Vascular and Abdominal Surgery, Medical Institute of Ministry of Interior (MVR-Sofia), Generel Skobelev 79, 1606, Sofia, Bulgaria.
authors.forename: Ilia
authors.initials: I
authors.lastname: Lozev
authors.affiliation: Chair of Dermatology, University of Rome "G. Marconi", Rome, Italy.
authors.forename: Torello
authors.initials: T
authors.lastname: Lotti
authors.affiliation: Department of Dermatopathology, St John's Institute of Dermatology, St Thomas' Hospital, London, UK.
authors.forename: Jose Carlos
authors.initials: JC
authors.lastname: Cardoso
authors.affiliation: Department of Pathology, University of Virginia Health System, 1215 Lee Street, 800214, 22908, Charlottesville, VA, USA.
authors.forename: James W
authors.initials: JW
authors.lastname: Patterson
mesh_terms: D000368:Aged; D002280:Basal Cell Carcinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005153:Facial Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005546:Forehead / Q000601:surgery; D006801:Humans; D007636:Keratoacanthoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012225:Rhinoplasty; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D013536:Suture Techniques
keywords: BCC; Outcome; Skin cancer; Surgery; Treatment