title: Gamma-band neural synchrony due to autobiographical fact violation in a self-referential question.
abstract: Our purpose was to investigate the cortical information processing of autobiographical fact violation (AFV) in self-referential questions. We expected that AFV in a self-referential question would evoke a characteristic pattern of neural synchrony and event-related potentials (ERPs). Averaged ERP and event-related synchronization in the gamma band were analyzed to observe differences between the processing of questions with and without AFV. Significant differences in ERP were found in the posterior area at 290-435ms (N400) and in the frontal area at 520-800ms (late positive component, LPC). Interestingly, differentiation of the gamma-band synchrony was found in two temporal periods, (255-365 and 525-585ms), which are comparable to the periods of significant ERP differences. The two periods are interpreted to be devoted to the processing of semantic and self-referential information, respectively. These findings may imply that the decision-making involved in answering self-referential questions is enabled by the integration of semantic and autobiographical information processing.
authors.affiliation: Department of Biomedical Engineering, College of Health Science, Yonsei University, 234 Maeji-ri, Heungup-myun, Wonju, Gangwon-do 26493, South Korea.
authors.forename: Jeong Woo
authors.initials: JW
authors.lastname: Choi
authors.affiliation: Department of Biomedical Engineering, College of Health Science, Yonsei University, 234 Maeji-ri, Heungup-myun, Wonju, Gangwon-do 26493, South Korea.
authors.forename: Kwang Su
authors.initials: KS
authors.lastname: Cha
authors.affiliation: Department of Neurology, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 03080, South Korea.
authors.forename: Ki-Young
authors.initials: KY
authors.lastname: Jung
authors.affiliation: Department of Biomedical Engineering, College of Health Science, Yonsei University, 234 Maeji-ri, Heungup-myun, Wonju, Gangwon-do 26493, South Korea. Electronic address: khkim0604@yonsei.ac.kr.
authors.forename: Kyung Hwan
authors.initials: KH
authors.lastname: Kim
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology; D004569:Electroencephalography / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D008014:Lie Detection; D008297:Male; D008606:Mental Processes / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D057566:Self Report; D012660:Semantics; D055815:Young Adult
keywords: Autobiographical fact violation (AFV); Event-related potential (ERP); Gamma-band synchrony; N400; Self-referential questions