title: Cluster headache and macroprolactinoma: Case report of a rare, but potential important causality.
abstract: While headache is not an uncommon symptom in patients suffering from pituitary adenomas, cluster headache (CH) has rarely been reported in such cases. Headache associated with hyperprolactinemia has been reported to be responsive to dopamine agonists (DA agonists) in many patients. We report on a patient with refractory CH secondary to a macroprolactinoma who showed immediate and permanent clinical and radiologic recovery following medical treatment with DA agonists. Measurement of prolactin levels in addition to cranial magnetic resonance imaging might be considered in patients with refractory CH, until the significance of this potential causality becomes clearer.
authors.affiliation: Department of Neurosurgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
authors.forename: Lukas
authors.initials: L
authors.lastname: Andereggen
authors.affiliation: Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
authors.forename: Marie-Luise
authors.initials: ML
authors.lastname: Mono
authors.affiliation: Department of Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
authors.forename: Frauke
authors.initials: F
authors.lastname: Kellner-Weldon
authors.affiliation: Department of Endocrinology, Universtiy Hospital Basel, University of Basel, Basel, Switzerland. Electronic address: emanuel.christ@usb.ch.
authors.forename: Emanuel
authors.initials: E
authors.lastname: Christ
mesh_terms: D003027:Cluster Headache / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D018491:Dopamine Agonists / Q000627:therapeutic use; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood; D015175:Prolactinoma / Q000150:complications / Q000175:diagnosis*
chemical_list: D018491:Dopamine Agonists; D011388:Prolactin
keywords: Cluster headache; Dopamine agonists; Prolactinoma