title: Proteomics reveals a new DNA repair factor involved in DNA damage signaling.
abstract: Stalling of the DNA replication machinery activates the ATR checkpoint kinase, which coordinates the cellular responses to replication stress. New studies identify a novel ATR activator, ETAA1, which is indispensable for the maintenance of genome integrity. Dysregulation of ETAA1 may contribute to the development of pancreatic cancer.
authors.affiliation: Department of Molecular Genetics, TU Kaiserslautern , Kaiserslautern, Germany.
authors.forename: Markus
authors.identifier: 0000-0002-6737-7203
authors.initials: M
authors.lastname: Räschle
keywords: ATR signaling; DNA Replication checkpoint; DNA repair; Proteomics