title: Pseudotumor Cerebri as the First Manifestation of Juvenile Systemic Lupus Erythematosus.
abstract: BACKGROUND
  Headache is a common neuropsychiatric manifestation of juvenile systemic lupus erythematous (JSLE). Pseudotumor cerebri (PTC) is an uncommon cause of headache, presenting especially in active JSLE. In this paper, we report a case of missed intractable headache that was eventually diagnosed as PTC and presented as the first manifestation of JSLE.
  
  
  METHODS
  A 9-year-old girl with a history of progressive headache for four months, fever, fatigue, myalgia, arthralgia, small-joint arthritis of the hands, and recent diplopia was referred to our clinic. The diagnosis of PTC in the background of JSLE was made based on her history, physical examination, positive laboratory findings, and increased intracranial pressure, with normal neuroimaging. Treatment with high-dose prednisolone led to dramatic resolution of the headache.
  
  
  CONCLUSIONS
  It seems that a complete neurologic examination in newly diagnosed SLE patients is mandatory, especially in the presence of any neuropsychiatric manifestations, such as headache.
authors.affiliation: Department of Pediatrics, Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Seyed-Reza
authors.initials: SR
authors.lastname: Raeeskarami
authors.affiliation: Department of Pediatrics, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Leila
authors.initials: L
authors.lastname: Shahbaznejad
authors.affiliation: Department of Pediatrics, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Raheleh
authors.initials: R
authors.lastname: Assari
authors.affiliation: Department of Pediatrics, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Yahya
authors.initials: Y
authors.lastname: Aghighi
keywords: Headache; Lupus Erythematosus; Pseudotumor Cerebri