title: Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody.
abstract: Drug induced lupus erythematosus (DIL or DILE) is an autoimmune disorder caused by chronic use of certain drugs. We report a unique case of hydralazine induced lupus syndrome (HILS) with a negative antinuclear antibody in a female patient who was on hydralazine for a period of 1.5-2 years and developed recurrent pericardial effusion as a result of it. Initially her condition was managed with a pericardial window. The recurrence of a massive pericardial effusion necessitated a right hemipericardiectomy. After hydralazine was stopped, she never had any further episodes of pericardial effusion or tamponade.
authors.affiliation: Department of Pulmonary and Critical Care, University of Tennessee Health Science Center, Memphis, TN, USA.
authors.forename: Praneet
authors.initials: P
authors.lastname: Iyer
authors.affiliation: Department of Internal Medicine, Seton Hall University School of Health and Medical Sciences, Saint Francis Medical Center, Trenton, NJ, USA.
authors.forename: Ahmed
authors.identifier: 0000-0002-6317-832X
authors.initials: A
authors.lastname: Dirweesh
authors.affiliation: Department of Internal Medicine, Seton Hall University School of Health and Medical Sciences, Saint Francis Medical Center, Trenton, NJ, USA.
authors.forename: Ritika
authors.initials: R
authors.lastname: Zijoo