title: A Rare Case of Multiple Myeloma with Biclonal Gammopathy.
abstract: Multiple myeloma is a debilitating malignancy arising from plasma cells. These malignant plasma cells called myeloma cells proliferate and infiltrate the bone marrow. The disease is characterized by the presence of a monoclonal protein in plasma and/or the urine. In this report, we present a case of biclonal multiple myeloma which showed two M bands on serum protein electrophoresis. The patient had elevated serum IgA and IgG levels. To reveal the nature of M bands or clonality, serum Immunofixation study was performed which revealed IgA with Lambda and IgG with Kappa light chains. Such pattern is very rare if we consider the various immunofixation patterns observed in different gammopathies.
authors.affiliation: Pathologist, Department of Clinical Chemistry and Immunoassays, SRL Central Clinical Reference Laboratory , Mumbai, Maharastra, India .
authors.forename: Abhik
authors.initials: A
authors.lastname: Banerjee
authors.affiliation: Biochemist, Department of Clinical Chemistry and Immunoassays, SRL Central Clinical Reference Laboratory , Mumbai, Maharastra, India .
authors.forename: Kshama
authors.initials: K
authors.lastname: Pimpalgaonkar
authors.affiliation: Biochemist, Department of Clinical Chemistry and Immunoassays, SRL Central Clinical Reference Laboratory , Mumbai, Maharastra, India .
authors.forename: Alap Lukiyas
authors.initials: AL
authors.lastname: Christy
keywords: Immunofixation electrophoresis; Neoplastic clonal disease; Serum protein electrophoresis