title: [Optimized detection and characterization of liver metastases : The role of current MRI contrast agents].
abstract: Metastases are the most common malignant lesions of the liver. The presence of liver metastases is an important prognostic factor and is decisive for the further management, especially in patients with colorectal cancer. Detection and characterization of liver metastases as well as differentiation from benign lesions are of high importance and a daily challenge in clinical radiology. Contrast-enhanced magnetic resonance imaging (MRI) has the highest sensitivity in detecting liver metastases. The sensitivity of MRI has been further increased due to the development of liver-specific contrast agents. This article describes the role of extracellular and hepatobiliary contrast agents for the detection and characterization of liver metastases. Moreover, the current knowledge on safety, sequence optimization, transient severe dyspnea and the combination of hepatobiliary with intravascular contrast agents for liver imaging is discussed.
authors.affiliation: Zentrum für Radiologie und Endoskopie, Klinik und Poliklinik für diagnostische und interventionelle Radiologie und Nuklearmedizin, Universitätsklinikum Hamburg-Eppendorf, Gebäude Ost 26, Martinistr. 52, 20246, Hamburg, Deutschland.
authors.forename: J M
authors.initials: JM
authors.lastname: Weinrich
authors.affiliation: Zentrum für Radiologie und Endoskopie, Klinik und Poliklinik für diagnostische und interventionelle Radiologie und Nuklearmedizin, Universitätsklinikum Hamburg-Eppendorf, Gebäude Ost 26, Martinistr. 52, 20246, Hamburg, Deutschland.
authors.forename: L
authors.initials: L
authors.lastname: Well
authors.affiliation: Zentrum für Radiologie und Endoskopie, Klinik und Poliklinik für diagnostische und interventionelle Radiologie und Nuklearmedizin, Universitätsklinikum Hamburg-Eppendorf, Gebäude Ost 26, Martinistr. 52, 20246, Hamburg, Deutschland. p.bannas@uke.de.
authors.forename: P
authors.initials: P
authors.lastname: Bannas
mesh_terms: D015179:Colorectal Neoplasms; D003287:Contrast Media; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D008279:Magnetic Resonance Imaging / Q000379:methods*
chemical_list: D003287:Contrast Media
keywords: Liver imaging; Prognosis; Sequence optimization; Treatment protocols; Tumor patients