title: Imaging Features of Idiopathic Intracranial Hypertension in Children.
abstract: Magnetic resonance imaging (MRI) signs of elevated intracranial pressure and idiopathic intracranial hypertension have been well characterized in adults but not in children. The MRIs of 50 children with idiopathic intracranial hypertension and 46 adults with idiopathic intracranial hypertension were reviewed for optic nerve head protrusion, optic nerve head enhancement, posterior scleral flattening, increased perioptic cerebrospinal fluid, optic nerve tortuosity, empty or partially empty sella, tonsillar herniation, enlargement of Meckel's cave meningoceles, and transverse venous sinus stenosis(TSS). Compared to adolescents (11-17 years, n = 40) and adults (>17 years, n = 46), prepubescent children (<11 years, n = 10) had lower frequencies of scleral flattening (50% vs 89% and 85%, P = .02), increased perioptic cerebrospinal fluid (60% vs 84% and 89%, P = .08), optic nerve tortuosity (20% vs 46% and 59%, P = .07), empty or partially empty sella (56% vs 78% and 93%, P = .007), and TSS (67% vs 93% and 96%, P = .04). Children with idiopathic intracranial hypertension have similar MRI findings as adults, but they are less frequent in prepubescent children.
authors.affiliation: 1 Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Alexander J P W
authors.initials: AJ
authors.lastname: Hartmann
authors.affiliation: 2 Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Bruno P
authors.initials: BP
authors.lastname: Soares
authors.affiliation: 1 Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.|3 Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.|4 Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, GA, USA.
authors.forename: Beau B
authors.initials: BB
authors.lastname: Bruce
authors.affiliation: 2 Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Amit M
authors.initials: AM
authors.lastname: Saindane
authors.affiliation: 1 Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.|3 Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.|5 Department of Neurological Surgery, Emory University School of Medicine, Atlanta, GA.
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Newman
authors.affiliation: 1 Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.|3 Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Valérie
authors.initials: V
authors.lastname: Biousse
authors.affiliation: 1 Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.|6 Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Jason H
authors.initials: JH
authors.lastname: Peragallo
mesh_terms: D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging* / Q000254:growth & development; D002648:Child; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D009898:Optic Disk / Q000000981:diagnostic imaging* / Q000254:growth & development
keywords: MRI; Pseudotumor cerebri; intracranial pressure; pediatric