title: Resolution of Q Fever-Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment.
abstract: Immunologic phenomena can complicate chronic infections withCoxiella burnetii(Q fever), including immune complex deposition causing vasculitis, neuropathy, and glomerulonephritis. We describe the case of a man with Q fever endocarditis, mixed cryoglobulinemia, and life-threatening vasculitis driven by immune complex deposition who was successfully treated with B cell depleting therapy (rituximab).
authors.affiliation: University of Colorado, Aurora, CO, USA.
authors.forename: Kellie L
authors.initials: KL
authors.lastname: Hawkins
authors.affiliation: University of Colorado, Aurora, CO, USA; Denver Veterans Affairs Medical Center, Denver, CO, USA.
authors.forename: Edward N
authors.initials: EN
authors.lastname: Janoff
authors.affiliation: University of Colorado, Aurora, CO, USA; Denver Veterans Affairs Medical Center, Denver, CO, USA.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Janson
keywords: Q fever; cryoglobulinemia; endocarditis; rituximab