title: Regioselective synthesis of difluoroalkyl/perfluoroalkyl enones via Pd-catalyzed four-component carbonylative coupling reactions.
abstract: The first example of Pd-catalyzed four-component carbonylative difluoroalkylation/perfluoroalkylation through the alkyne difunctionalization process is achieved. The reaction proceeds smoothly under mild conditions in the presence of 1 atm of CO at room temperature with good yields and E-selectivities. The utilization of CsF as an additive is vital to the success of the reaction.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liangym@lzu.edu.cn.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liangym@lzu.edu.cn.
authors.forename: Lan
authors.initials: L
authors.lastname: Zheng
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liangym@lzu.edu.cn.
authors.forename: Yu-Tao
authors.initials: YT
authors.lastname: He
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China. liangym@lzu.edu.cn.
authors.forename: Yong-Min
authors.identifier: http://orcid.org/0000-0001-8280-8211
authors.initials: YM
authors.lastname: Liang