title: Hepatoid Adenocarcinoma of the Extrahepatic Bile Duct in a Patient with Polysplenia Syndrome.
abstract: Hepatoid adenocarcinoma (HAC) is a rare subtype of extrahepatic adenocarcinoma that is characterized by its morphological and functional similarities to hepatocellular carcinoma. We herein present a novel case of HAC arising from the extrahepatic bile duct in a 75-year-old Japanese woman with polysplenia syndrome. This is the second reported case of HAC arising from this site. The tumor induced jaundice and hemobilia. A total of four isolated intraductal polypoid masses of HAC were found. No recurrence was seen five months after surgery. Further reports of similar cases will be needed to clarify the clinical characteristics and the prognosis of this malignancy.
authors.affiliation: Department of Diagnostic Pathology, Japanese Red Cross Kochi Hospital, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Yorita
authors.forename: Shiori
authors.initials: S
authors.lastname: Sasaki
authors.forename: Ai
authors.initials: A
authors.lastname: Kawada
authors.forename: Michiyo
authors.initials: M
authors.lastname: Okazaki
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Yamai
authors.forename: Kunihisa
authors.initials: K
authors.lastname: Uchita
authors.forename: Shinichi
authors.initials: S
authors.lastname: Iwamura
authors.forename: Kimiko
authors.initials: K
authors.lastname: Nakatani
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ito
authors.forename: Naoto
authors.initials: N
authors.lastname: Kuroda
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000368:Aged; D001650:Bile Duct Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D017734:Bile Ducts, Extrahepatic; D001706:Biopsy; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006431:Hemobilia / Q000209:etiology; D059446:Heterotaxy Syndrome / Q000150:complications*; D006801:Humans; D011379:Prognosis; D014463:Ultrasonography