title: sfinx: an R package for the elimination of false positives from affinity purification-mass spectrometry datasets.
abstract: CONCLUSIONS
  We describe sfinx, an R package providing access to the straightforward filtering index (SFINX) for the separation of true positive from false positive protein interactions in affinity purification - mass spectrometry datasets. This package maintains the reliability and user-friendliness of the SFINX web site interface but is faster, unlimited in input size, and can be run locally within R.
  
  
  METHODS
  The sfinx R package is available for download at the comprehensive R archive network (CRAN) https://cran.r-project.org/web/packages/sfinx/ under the Apache License 2.0.
  
  
  BACKGROUND
  sven.eyckerman@vib-ugent.be or kevin.titeca@gmail.com.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium.|Department of Biochemistry, Ghent University, Ghent, Belgium.
authors.forename: Kevin
authors.initials: K
authors.lastname: Titeca
authors.affiliation: Advanced Database Research and Modelling (ADReM), Department of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium.|Biomedical Informatics Research Center Antwerp (biomina), University of Antwerp/Antwerp University Hospital, Edegem, Belgium.
authors.forename: Pieter
authors.initials: P
authors.lastname: Meysman
authors.affiliation: Advanced Database Research and Modelling (ADReM), Department of Mathematics and Computer Science, University of Antwerp, Antwerp, Belgium.|Biomedical Informatics Research Center Antwerp (biomina), University of Antwerp/Antwerp University Hospital, Edegem, Belgium.
authors.forename: Kris
authors.initials: K
authors.lastname: Laukens
authors.affiliation: VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium.|Department of Biochemistry, Ghent University, Ghent, Belgium.|Bioinformatics Institute Ghent, Ghent University, Zwijnaarde, Belgium.
authors.forename: Lennart
authors.initials: L
authors.lastname: Martens
authors.affiliation: VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium.|Department of Biochemistry, Ghent University, Ghent, Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Tavernier
authors.affiliation: VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium.|Department of Biochemistry, Ghent University, Ghent, Belgium.
authors.forename: Sven
authors.initials: S
authors.lastname: Eyckerman
mesh_terms: D013058:Mass Spectrometry / Q000379:methods*; D040901:Proteomics / Q000379:methods*; D015203:Reproducibility of Results; D012984:Software