title: Perioperative participation of orthopedic patients and surgical staff in a nasal decolonization intervention to reduce Staphylococcus spp surgical site infections.
abstract: With the goal of reducing rates of surgical site infections in our spine patients, we initiated a trial to investigate the impact of adding perisurgical nasal decolonization involving patients and surgical and nursing staff. We combined immediate presurgical application of a nonantibiotic alcohol-based nasal antiseptic with existing chlorhexidine bath or wipes in a comprehensive pre- and postoperative decolonization protocol. Mean infection rates were significantly decreased by 81% from 1.76 to 0.33 per 100 surgeries during the 15-month trial, when compared with the prior 9-month baseline.
authors.affiliation: Baylor Orthopedic and Spine Hospital at Arlington, Arlington, TX. Electronic address: amullen@uspi.com.
authors.forename: Anildaliz
authors.initials: A
authors.lastname: Mullen
authors.affiliation: Baylor Orthopedic and Spine Hospital at Arlington, Arlington, TX.
authors.forename: Helen J
authors.initials: HJ
authors.lastname: Wieland
authors.affiliation: Baylor Orthopedic and Spine Hospital at Arlington, Arlington, TX.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Wieser
authors.affiliation: Johns Hopkins University School of Public Health, Baltimore, MD.
authors.forename: Ernst W
authors.initials: EW
authors.lastname: Spannhake
authors.affiliation: Baylor Orthopedic and Spine Hospital at Arlington, Arlington, TX.
authors.forename: Rebecca S
authors.initials: RS
authors.lastname: Marinos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000985:Antisepsis / Q000379:methods*; D002353:Carrier State / Q000188:drug therapy*; D005260:Female; D006282:Health Personnel; D006302:Health Services Research; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000382:microbiology; D019637:Orthopedic Procedures / Q000009:adverse effects*; D010361:Patients; D013203:Staphylococcal Infections / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D055815:Young Adult
keywords: Alcohol-based nasal antiseptic; Anterior nares; Perioperative nasal decolonization; Spine surgery; Staff nasal decolonization