title: Anti-oxidative aspect of inhaled anesthetic gases against acute brain injury.
abstract: Acute brain injury is a critical and emergent condition in clinical settings, which needs to be addressed urgently. Commonly acute brain injuries include traumatic brain injury, ischemic and hemorrhagic strokes. Oxidative stress is a key contributor to the subsequent injuries and impedes the reparative process after acute brain injury; therefore, facilitating an anti-oxidative approach is important in the care of those diseases. Readiness to deliver and permeability to blood brain barrier are essential for the use of this purpose. Inhaled anesthetic gases are a group of such agents. In this article, we discuss the anti-oxidative roles of anesthetic gases against acute brain injury.
authors.affiliation: Department of Neurology, Pittsburgh Institute of Brain Disorders and Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Tuo
authors.initials: T
authors.lastname: Yang
authors.affiliation: Department of Neurology, Pittsburgh Institute of Brain Disorders and Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Yang
authors.initials: Y
authors.lastname: Sun
authors.affiliation: Department of Neurology, Pittsburgh Institute of Brain Disorders and Recovery, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research, Educational and Clinical Center, Veterans Affairs Pittsburgh Health Care System, Pittsburgh, PA, USA; Key Lab of Cerebral Microcirculation in Universities of Shandong, Taishan Medical University, Taian, Shandong Province, China.
authors.forename: Feng
authors.identifier: 0000-0001-7275-9989
authors.initials: F
authors.lastname: Zhang
keywords: isoflurane; nuclear factor (erythroid-derived 2)-like 2; post-conditioning; pre-conditioning; sevoflurane; stroke; traumatic brain injury; xenon