title: Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis.
abstract: It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included in the final meta-analysis. Several perioperative and postoperative variables were compared. A total of 8 studies with 3858 patients were included in the analysis. Of these patients, 19% underwent neonatal repair. Neonatal repair was associated with increased mortality, longer intensive care unit stays, and longer total hospital length of stay.
authors.affiliation: Division of Cardiology and Cardiothoracic Surgery, Children's Hospital of Wisconsin/ Medical College of Wisconsin, 9000 Wisconsin Avenue, Milwaukee, WI, 53226, USA. loomba.rohit@gmail.com.
authors.forename: Rohit S
authors.initials: RS
authors.lastname: Loomba
authors.affiliation: Division of Cardiology and Cardiothoracic Surgery, Children's Hospital of Wisconsin/ Medical College of Wisconsin, 9000 Wisconsin Avenue, Milwaukee, WI, 53226, USA.
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Buelow
authors.affiliation: Division of Cardiology and Cardiothoracic Surgery, Children's Hospital of Wisconsin/ Medical College of Wisconsin, 9000 Wisconsin Avenue, Milwaukee, WI, 53226, USA.
authors.forename: Ronald K
authors.initials: RK
authors.lastname: Woods
mesh_terms: D000367:Age Factors; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000401:mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D013771:Tetralogy of Fallot / Q000601:surgery*; D013997:Time Factors
keywords: Cyanosis; Hypoxia; Neonatal; Repair; Tetralogy of fallot; Timing