title: Pharmacologic Treatment of Opioid Addiction During Pregnancy.
abstract: Opioid addiction during pregnancy presents a treatment challenge to clinicians and women alike. Untreated addiction can lead to poor maternal and fetal health outcomes. Medication-assisted treatment is the standard of care, and methadone is the current drug of choice for treatment. Emerging evidence also supports the use of buprenorphine during pregnancy. Both methadone and buprenorphine have risks and benefits that should be explored before initiating treatment. Clinicians who work in obstetrics and in addiction treatment can collaborate and coordinate treatment to ensure optimal maternal and fetal outcomes. Women undergoing treatment will require frequent monitoring, particularly in the third trimester. Neonates born to women receiving treatment may have withdrawal symptoms and require additional treatment.
authors.forename: Lori
authors.initials: L
authors.lastname: Keough
authors.forename: Heidi Collins
authors.initials: HC
authors.lastname: Fantasia
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000009:adverse effects*; D002047:Buprenorphine / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008691:Methadone / Q000494:pharmacology / Q000627:therapeutic use; D009357:Neonatal Abstinence Syndrome / Q000188:drug therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D019966:Substance-Related Disorders / Q000188:drug therapy* / Q000523:psychology
chemical_list: D000701:Analgesics, Opioid; D002047:Buprenorphine; D008691:Methadone
keywords: buprenorphine; medication-assisted treatment; methadone; opioid; pregnancy