title: Volumetric Assessment of Regenerative Efficacy of Demineralized Freeze-Dried Bone Allograft With or Without Amnion Membrane in Grade II Furcation Defects: A Cone Beam Computed Tomography Study.
abstract: Volumetric changes were evaluated to assess the regenerative efficacy of demineralized freeze-dried bone allograft (DFDBA) with and without amnion membrane (AM) in Grade II furcation defects both clinically and radiographically using cone beam computed tomography (CBCT). Sites were randomly assigned to Group I (DFDBA) and Group II (DFDBA + AM). Clinical parameters such as probing pocket depth, clinical attachment level, gingival recession, and horizontal probing depth were assessed at baseline, 3 months, and 6 months. Radiographic dimensions of the defect height, width, depth, and volume were assessed at baseline and 6 months postoperatively. DFDBA used with AM resulted in significant improvement in clinical and radiographic parameters when compared with DFDBA alone. The mean reductions in radiographic volume of the defect were 11.15 ± 6.39 mL for Group I and 17.02 ± 10.86 mL for Group II. Greater reduction in volume indicated a greater amount of healed regenerated tissue in Group II patients.
authors.forename: Natasha G
authors.initials: NG
authors.lastname: Pajnigara
authors.forename: Abhay P
authors.initials: AP
authors.lastname: Kolte
authors.forename: Rajashri A
authors.initials: RA
authors.lastname: Kolte
authors.forename: Nilufer G
authors.initials: NG
authors.lastname: Pajnigara
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000601:surgery; D000650:Amnion / Q000637:transplantation*; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D003648:Decalcification Technique; D005260:Female; D005612:Freeze Drying; D017823:Furcation Defects / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D005889:Gingival Recession / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D006801:Humans; D007194:India; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D017622:Periodontal Attachment Loss / Q000601:surgery; D010514:Periodontal Pocket / Q000601:surgery
chemical_list: D018786:Bone Substitutes; D008567:Membranes, Artificial