title: Antimicrobial Treatment of Polymeric Medical Devices by Silver Nanomaterials and Related Technology.
abstract: Antimicrobial biocompatible polymers form a group of highly desirable materials in medicinal technology that exhibit interesting thermal and mechanical properties, and high chemical resistance. There are numerous types of polymers with antimicrobial activity or antimicrobial properties conferred through their proper modification. In this review, we focus on the second type of polymers, especially those whose antimicrobial activity is conferred by nanotechnology. Nanotechnology processing is a developing area that exploits the antibacterial effects of broad-scale compounds, both organic and inorganic, to form value-added medical devices. This work gives an overview of nanostructured antimicrobial agents, especially silver ones, used together with biocompatible polymers as effective antimicrobial composites in healthcare. The bactericidal properties of non-conventional antimicrobial agents are compared with those of conventional ones and the advantages and disadvantages are discussed.
authors.affiliation: Department of Solid State Engineering, University of Chemistry and Technology Prague, Prague 166 28, Czech Republic. polivkoa@vscht.cz.
authors.forename: Markéta
authors.initials: M
authors.lastname: Polívková
authors.affiliation: Institute of Hydrobiology, Biology Centre of the AS CR, Ceske Budejovice 370 05, Czech Republic. hubacektom@gmail.com.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Hubáček
authors.affiliation: Department of Solid State Engineering, University of Chemistry and Technology Prague, Prague 166 28, Czech Republic. marek.staszek@vscht.cz.
authors.forename: Marek
authors.initials: M
authors.lastname: Staszek
authors.affiliation: Department of Solid State Engineering, University of Chemistry and Technology Prague, Prague 166 28, Czech Republic. vaclav.svorcik@vscht.cz.
authors.forename: Václav
authors.initials: V
authors.lastname: Švorčík
authors.affiliation: Department of Solid State Engineering, University of Chemistry and Technology Prague, Prague 166 28, Czech Republic. Jakub.Siegel@vscht.cz.
authors.forename: Jakub
authors.initials: J
authors.lastname: Siegel
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry; D003428:Cross Infection / Q000382:microbiology / Q000517:prevention & control / Q000635:transmission; D004203:Disinfection / Q000379:methods; D004864:Equipment and Supplies / Q000382:microbiology; D006801:Humans; D049329:Nanostructures / Q000737:chemistry / Q000648:ultrastructure; D036103:Nanotechnology; D011108:Polymers / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013499:Surface Properties
chemical_list: D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D011108:Polymers; D012834:Silver
keywords: antimicrobials; biocompatibility; medical devices; modification; nanostructures; polymers