title: Photocyclization of photoswitches with high enantioselectivity in human serum albumin in an artificial environment.
abstract: Three photochromic bisthienylethenes exhibited 56 to >99% enantiomeric excess in photochemical ring closure upon UV irradiation when incorporated in human serum albumin dissolved in 15% acetonitrile-phosphate buffer solution and incubated for 24 h at -4 °C. The absolute stereochemistry of the major enantiomers of two bisthienylethenes has been determined by their chemical transformations.
authors.affiliation: Department of Advanced Materials Chemistry, Graduate School of Engineering, Yokohama National University, 79-5, Tokiwadai, Hodogaya, Yokohama 240-8501, Japan. yokoyama-yasushi-wp@ynu.ac.jp.
authors.forename: Koichi
authors.initials: K
authors.lastname: Kawamura
authors.affiliation: Department of Advanced Materials Chemistry, Graduate School of Engineering, Yokohama National University, 79-5, Tokiwadai, Hodogaya, Yokohama 240-8501, Japan. yokoyama-yasushi-wp@ynu.ac.jp.
authors.forename: Ken
authors.initials: K
authors.lastname: Osawa
authors.affiliation: Department of Advanced Materials Chemistry, Graduate School of Engineering, Yokohama National University, 79-5, Tokiwadai, Hodogaya, Yokohama 240-8501, Japan. yokoyama-yasushi-wp@ynu.ac.jp.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Watanobe
authors.affiliation: Department of Advanced Materials Chemistry, Graduate School of Engineering, Yokohama National University, 79-5, Tokiwadai, Hodogaya, Yokohama 240-8501, Japan. yokoyama-yasushi-wp@ynu.ac.jp.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Saeki
authors.affiliation: Department of Advanced Materials Chemistry, Graduate School of Engineering, Yokohama National University, 79-5, Tokiwadai, Hodogaya, Yokohama 240-8501, Japan. yokoyama-yasushi-wp@ynu.ac.jp.
authors.forename: Naoki
authors.initials: N
authors.lastname: Maruyama
authors.affiliation: Department of Advanced Materials Chemistry, Graduate School of Engineering, Yokohama National University, 79-5, Tokiwadai, Hodogaya, Yokohama 240-8501, Japan. yokoyama-yasushi-wp@ynu.ac.jp.
authors.forename: Yasushi
authors.identifier: http://orcid.org/0000-0002-8654-1320
authors.initials: Y
authors.lastname: Yokoyama
mesh_terms: D003500:Cyclization; D005030:Ethylenes / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D055668:Photochemical Processes; D012709:Serum Albumin / Q000737:chemistry*; D013237:Stereoisomerism; D014466:Ultraviolet Rays
chemical_list: D005030:Ethylenes; D012709:Serum Albumin