title: Mapping to Estimate Health-State Utility from Non-Preference-Based Outcome Measures: An ISPOR Good Practices for Outcomes Research Task Force Report.
abstract: Economic evaluation conducted in terms of cost per quality-adjusted life-year (QALY) provides information that decision makers find useful in many parts of the world. Ideally, clinical studies designed to assess the effectiveness of health technologies would include outcome measures that are directly linked to health utility to calculate QALYs. Often this does not happen, and even when it does, clinical studies may be insufficient for a cost-utility assessment. Mapping can solve this problem. It uses an additional data set to estimate the relationship between outcomes measured in clinical studies and health utility. This bridges the evidence gap between available evidence on the effect of a health technology in one metric and the requirement for decision makers to express it in a different one (QALYs). In 2014, ISPOR established a Good Practices for Outcome Research Task Force for mapping studies. This task force report provides recommendations to analysts undertaking mapping studies, those that use the results in cost-utility analysis, and those that need to critically review such studies. The recommendations cover all areas of mapping practice: the selection of data sets for the mapping estimation, model selection and performance assessment, reporting standards, and the use of results including the appropriate reflection of variability and uncertainty. This report is unique because it takes an international perspective, is comprehensive in its coverage of the aspects of mapping practice, and reflects the current state of the art.
authors.affiliation: School of Health and Related Research, University of Sheffield, Sheffield, UK. Electronic address: a.j.wailoo@sheffield.ac.uk.
authors.forename: Allan J
authors.initials: AJ
authors.lastname: Wailoo
authors.affiliation: School of Health and Related Research, University of Sheffield, Sheffield, UK.
authors.forename: Monica
authors.initials: M
authors.lastname: Hernandez-Alava
authors.affiliation: Centre for Health Economics, University of York, York, UK.
authors.forename: Andrea
authors.initials: A
authors.lastname: Manca
authors.affiliation: Instituto de Evaluación Tecnológica en Salud, Bogota, Colombia.
authors.forename: Aurelio
authors.initials: A
authors.lastname: Mejia
authors.affiliation: F. Hoffmann-La Roche, Basel, Switzerland.
authors.forename: Joshua
authors.initials: J
authors.lastname: Ray
authors.affiliation: IMS Health, Tokyo, Japan.
authors.forename: Bruce
authors.initials: B
authors.lastname: Crawford
authors.affiliation: Pharmerit International, Bethesda, MD, USA.
authors.forename: Marc
authors.initials: M
authors.lastname: Botteman
authors.affiliation: Department of Psychiatry, Section Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: Jan
authors.initials: J
authors.lastname: Busschbach
mesh_terms: D026683:Advisory Committees; D003362:Cost-Benefit Analysis; D003661:Decision Support Techniques; D006304:Health Status; D006801:Humans; D008962:Models, Theoretical; D017063:Outcome Assessment, Health Care / Q000379:methods* / Q000592:standards*; D019057:Quality-Adjusted Life Years; D015203:Reproducibility of Results; D012107:Research Design / Q000592:standards*
keywords: economic evaluation; health utility; mapping; quality of life