title: Echocardiographic correlates are associated with in-hospital mortality in trauma and burn patients.
abstract: BACKGROUND
  The role of echocardiographic indices of preload and contractility in predicting outcomes is unknown. We report the association of end diastolic area (EDA) and fractional area of change (FAC) with mortality in a cohort of trauma and burn patients.
  
  
  METHODS
  Data on 86 patients admitted to a tertiary care center between July 2013 and July 2015 were reviewed. The association between abnormal EDA and FAC and adverse clinical outcomes was tested using exact logistic regression analysis.
  
  
  RESULTS
  31 patients had abnormal EDA (<10 cm2) and 13 had low FAC (<40%). Those with low FAC had higher blood pressure on admission, and lower urine output and higher lactic acid (p= < 0.01) on echocardiography day. Abnormal EDA was associated with in-hospital death (OR 4.20, 95% CI 1.45-12.17).
  
  
  CONCLUSIONS
  Echocardiographic measurements can predict outcome in trauma and burn patients. Further studies are needed to confirm these findings.
authors.affiliation: Department of Surgery, Division of Acute Care Surgery, University of Alabama at Birmingham, Birmingham, AL, 35294, USA. Electronic address: dyounan@uabmc.edu.
authors.forename: Duraid
authors.initials: D
authors.lastname: Younan
authors.affiliation: Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
authors.forename: Russell
authors.initials: R
authors.lastname: Griffin
authors.affiliation: Department of Surgery, Division of Acute Care Surgery, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
authors.forename: Donald
authors.initials: D
authors.lastname: Reiff
authors.affiliation: Department of Surgery, Division of Acute Care Surgery, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Richey
authors.affiliation: Department of Surgery, Division of Acute Care Surgery, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Schinnerer
authors.affiliation: Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Pittet
authors.affiliation: Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Zaky
mesh_terms: D002056:Burns / Q000401:mortality; D017548:Echocardiography, Transesophageal; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014947:Wounds and Injuries / Q000401:mortality*