title: [Splenic abscesses: From diagnosis to therapy].
abstract: Splenic abscess is septic collection which occurs after haematogenous spread or local dissemination. Splenic abscess is an uncommon and rare condition, more frequently affecting male and immunocompromised patients. There are no guidelines regarding its diagnosis and management. Computed tomography (CT) scan is highly sensitive and specific (95% and 92%, respectively) in the diagnosis of splenic abscess. Diagnosis is based on blood cultures which are positive in 24 to 80% of cases. Bacterial growth culture of abscess after drainage is more efficient (50-80%) and can be performed after surgery or percutaneous drainage under imaging, including CT scan. Microorganisms involved are frequently enterobacteriaceae, gram-positive cocci and anaerobes. This particular ecology leads to an empiric broad-spectrum antibiotic therapy, with a variable duration, from 10days to more than one month. Management remains very close to the one applied in case of liver abscesses. The role of splenectomy in the prevention of recurrence remains controversial. We reviewed the literature regarding splenic abscesses, from diagnosis to therapy.
authors.affiliation: Service de médecine interne, hôpital Ambroise-Paré, hôpitaux universitaires Paris Île-de-France Ouest, 92200 Boulogne-Billancourt, France; Service de maladies infectieuses, hôpital Raymond-Poincaré, hôpitaux universitaires Paris Île-de-France Ouest, 104, boulevard Raymond-Poincaré, 92380 Garches, France. Electronic address: benjamin.davido@aphp.fr.
authors.forename: B
authors.initials: B
authors.lastname: Davido
authors.affiliation: Service de médecine interne, hôpital Ambroise-Paré, hôpitaux universitaires Paris Île-de-France Ouest, 92200 Boulogne-Billancourt, France; Service de maladies infectieuses, hôpital Raymond-Poincaré, hôpitaux universitaires Paris Île-de-France Ouest, 104, boulevard Raymond-Poincaré, 92380 Garches, France.
authors.forename: A
authors.initials: A
authors.lastname: Dinh
authors.affiliation: Service de médecine interne, hôpital Ambroise-Paré, hôpitaux universitaires Paris Île-de-France Ouest, 92200 Boulogne-Billancourt, France.
authors.forename: E
authors.initials: E
authors.lastname: Rouveix
authors.affiliation: Service de maladies infectieuses, hôpital Raymond-Poincaré, hôpitaux universitaires Paris Île-de-France Ouest, 104, boulevard Raymond-Poincaré, 92380 Garches, France; Service de gastro-entérologie, nutrition transversale, hôpital Ambroise-Paré, hôpitaux universitaires Paris Île-de-France Ouest, 92200 Boulogne-Billancourt, France.
authors.forename: P
authors.initials: P
authors.lastname: Crenn
authors.affiliation: Service de médecine interne, hôpital Ambroise-Paré, hôpitaux universitaires Paris Île-de-France Ouest, 92200 Boulogne-Billancourt, France.
authors.forename: T
authors.initials: T
authors.lastname: Hanslik
authors.affiliation: Service de maladies infectieuses, hôpital Raymond-Poincaré, hôpitaux universitaires Paris Île-de-France Ouest, 104, boulevard Raymond-Poincaré, 92380 Garches, France.
authors.forename: J
authors.initials: J
authors.lastname: Salomon
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D001424:Bacterial Infections / Q000175:diagnosis / Q000382:microbiology; D001431:Bacteriological Techniques / Q000379:methods; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008100:Liver Abscess / Q000175:diagnosis / Q000628:therapy; D008297:Male; D013158:Splenic Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*
keywords: Abcès de la rate; Antibiotic; Antibiotique; Diagnosis; Diagnostic; Imagerie; Imaging; Splenic abscess; Traitement; Treatment