title: Strategies for Targeted Therapy in Head and Neck Squamous Cell Carcinoma Using WEE1 Inhibitor AZD1775.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
authors.forename: Michael
authors.initials: M
authors.lastname: Kao
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
authors.forename: Carlos
authors.initials: C
authors.lastname: Green
authors.affiliation: Department of Pathology, University of Washington, Seattle.
authors.forename: Julia
authors.initials: J
authors.lastname: Sidorova
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Méndez
mesh_terms: D002453:Cell Cycle / Q000187:drug effects; D018797:Cell Cycle Proteins / Q000037:antagonists & inhibitors*; D045744:Cell Line, Tumor; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D009687:Nuclear Proteins / Q000037:antagonists & inhibitors*; D017410:Practice Guidelines as Topic; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D011720:Pyrazoles / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use*; D011744:Pyrimidinones; D000077195:Squamous Cell Carcinoma of Head and Neck / Q000188:drug therapy* / Q000473:pathology
chemical_list: D018797:Cell Cycle Proteins; D004791:Enzyme Inhibitors; D009687:Nuclear Proteins; D011720:Pyrazoles; D011743:Pyrimidines; D011744:Pyrimidinones; D011505:Protein-Tyrosine Kinases; C499349:WEE1 protein, human; C549567:adavosertib