title: Measurements of myocardial bridges on computed tomography predict presence of clinical symptoms and outcomes of adverse heart events: a retrospective study in a large population from China.
abstract: Background Clinical-radiological correlation of myocardial bridge (MB) remains unclear. Purpose To correlate clinical symptoms and outcomes of MBs with computed tomography (CT) coronary angiography findings. Material and Methods A total of 2092 patients with CT coronary angiography were collected. Patients were divided into symptomatic and asymptomatic groups, adverse heart events (AHE) and non-AHE groups, MB and non-MB groups, as well as left anterior descending (LAD)-MB and non-LAD-MB groups. Statistical analyses were performed to identify inter-group differences, and clinical-radiological correlations of MBs or mural coronary arteries (MCAs). Results The prevalence of MB, the MCA stenosis either in systole or in diastole, and the ratio of LAD-MB were significantly higher in the symptomatic group than in the asymptomatic group, and higher in the AHE group than in the non-AHE group ( P all <0.05). MB thickness, systolic MCA stenosis, and diastolic MCA stenosis were independent variables predicting clinical symptoms ( P < 0.05), with diastolic MCA stenosis having the highest diagnostic performance, when cutting at 24.6%. The corresponding sensitivity and specificity were 87.8% and 90.6%, respectively. Diastolic MCA stenosis independently indicated outcome of AHE (odds ratio, 1.047; P < 0.001). Conclusion Measurements of MB-MCA by CT predict the presence of clinical symptoms and outcomes of AHE, with diastolic MCA stenosis possessing the greatest performance.
authors.affiliation: 1 Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, PR China.
authors.forename: Guobing
authors.initials: G
authors.lastname: Liu
authors.affiliation: 1 Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, PR China.
authors.forename: Yanjuan
authors.initials: Y
authors.lastname: Qu
authors.affiliation: 2 Department of Radiology, Wuhan Asia Heart Hospital, Wuhan, PR China.
authors.forename: Xin
authors.initials: X
authors.lastname: Chen
authors.affiliation: 1 Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, PR China.
authors.forename: Meiyan
authors.initials: M
authors.lastname: Liao
authors.affiliation: 1 Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, PR China.
authors.forename: Huijuan
authors.initials: H
authors.lastname: Hu
authors.affiliation: 1 Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, PR China.
authors.forename: Yiyuan
authors.initials: Y
authors.lastname: Cao
authors.affiliation: 1 Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, PR China.
authors.forename: Zhixiong
authors.initials: Z
authors.lastname: Tian
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D000072226:Computed Tomography Angiography / Q000379:methods*; D017023:Coronary Angiography / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D054084:Myocardial Bridging / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
keywords: Myocardial bridge; computed tomography (CT); dual-source CT; mural coronal artery