title: The Conversion of tert-Butyl Esters to Acid Chlorides Using Thionyl Chloride.
abstract: The reaction of tert-butyl esters with SOCl2at room temperature provides acid chlorides in unpurified yields of 89% or greater. Benzyl, methyl, ethyl, and isopropyl esters are essentially unreactive under these conditions, allowing for the selective conversion of tert-butyl esters to acid chlorides in the presence of other esters.
authors.affiliation: Department of Chemistry and Biochemistry, University of Colorado Boulder , Boulder, Colorado 80309, United States.
authors.forename: Jacob A
authors.initials: JA
authors.lastname: Greenberg
authors.affiliation: Department of Chemistry and Biochemistry, University of Colorado Boulder , Boulder, Colorado 80309, United States.
authors.forename: Tarek
authors.identifier: 0000-0003-3703-5672
authors.initials: T
authors.lastname: Sammakia