title: Histological evaluation of direct pulp capping with all-in-one adhesives in rat teeth.
abstract: The aim of this study was to histologically evaluate direct pulp capping using different all-in-one adhesives in rat teeth. Five all-in-one adhesives and a control material (MTA) were used. Each material was applied on the exposed pulp, and each cavity was subsequently restored with the resin composite. Rats were sacrificed 14 days after the surgical procedure. Serial stained sections were histologically evaluated for examining pulp tissue disorganization (PTD), inflammatory cell infiltration (ICI), dentin bridge formation (DBF), and bacterial penetration (BP). We found that rat pulps, which were direct capped with all-in-one adhesives, showed various degrees of PTD, ICI, and DBF depending on the material, and that there were no complete dentin bridges. In contrast, rat pulps capped with MTA showed no PTD and ICI, and there were complete dentin bridges in all, but one specimen. No BP was observed in any specimen.
authors.affiliation: Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata.
authors.forename: Koichi
authors.initials: K
authors.lastname: Shinkai
authors.affiliation: Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata.
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Taira
authors.affiliation: Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata.
authors.forename: Satoki
authors.initials: S
authors.lastname: Kawashima
authors.affiliation: Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata.
authors.forename: Shiro
authors.initials: S
authors.lastname: Suzuki
authors.affiliation: Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata.
authors.forename: Masaya
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000269:Adhesives; D000818:Animals; D002126:Calcium Hydroxide; D003782:Dental Pulp; D003785:Dental Pulp Capping; D003789:Dental Pulp Exposure; D003809:Dentin, Secondary; D051381:Rats; D019279:Resin Cements
chemical_list: D000269:Adhesives; D019279:Resin Cements; D002126:Calcium Hydroxide
keywords: All-in-one adhesive; Biocompatibility; Direct pulp capping; Histological evaluation; Rat pulp