title: A successful experience of the Iranian blood transfusion organization in improving accessibility and affordability of plasma derived medicine.
abstract: Plasma is the liquid part of blood. It is estimated 21.6 million liters of plasma collect from Whole blood annually. From these plasma, 4.2 million liters transfuse, 8.1 million liters fractionate, 9.3 million liters waste. Nowadays, blood products and PDM (plasma derived medicine) consider as essential medicine in modern health care and transfusion medicine. Iranian blood transfusion organization as a non-profit organization was established in 1974 in order to centralize all blood transfusion activities from donor recruitment to distribution of blood components to hospitals. Iran is the only country in EMR region with the rate of 20-29.9 blood donations per 1000 population and reached 100% voluntary non-remunerated blood donation in 2007. RBCs and platelets demand are much more than FFPs so the IBTO was faced the surplus plasma that could cause surplus plasma wastage. Simultaneously, hospitals need more plasma derived medicine especially albumin, IVIG, factor VIII, factor IX. IBTO was faced the challenges such as Fractionators selection, Plasma volume shipment, Contract duration, Product profile, Multiple External audits, Cold chain maintenance, Transporting plasma across international borders, NAT test. To overcome plasma wastage and storage of PDM. IBTO involved toll manufacturing in 2005 and not only prevents plasma wastage but also save MOH (ministry of health) budget.
authors.affiliation: Department of Immunohematology, Blood transfusion research Center, High Institute for Research and Education in Transfusion Medicine, P.O. Box: 14665-1157, Tehran, Iran. Electronic address: a.chegini@ibto.ir.
authors.forename: Azita
authors.initials: A
authors.lastname: Chegini
authors.affiliation: IBTO Iranian Blood Transfusion Organization plasma Committee, IBTO, Box: 14665-1157, Tehran, Iran. Electronic address: drtorab@hotmail.com.
authors.forename: Seyed Ardeshir
authors.initials: SA
authors.lastname: Torab
authors.affiliation: General Director of Iranian Blood Transfusion Organisation, Department of Immunology, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran. Electronic address: pourfa@yahoo.com.
authors.forename: Ali Akbar
authors.initials: AA
authors.lastname: Pourfatollah
mesh_terms: D001803:Blood Transfusion / Q000379:methods*; D006801:Humans; D007492:Iran; D010949:Plasma / Q000378:metabolism*; D064826:Transfusion Medicine / Q000379:methods*
keywords: Plasma; Plasma derived medicine