title: The Differentiation of Intestinal-Failure-Associated Liver Disease from Nonalcoholic Fatty Liver and Nonalcoholic Steatohepatitis.
abstract: Intestinal failure-associated liver disease (IFALD), formerly known as parenteral nutrition-associated liver disease has often been listed in textbooks as an example of nonalcoholic fatty liver disease (NAFLD). However, the etiology, pathophysiology, epidemiology, histology, and progression differ substantially between the conditions defined as NAFLD and the disease, IFALD. Therefore, IFALD should not be defined or considered as a type or a cause of nonalcoholic fatty liver or nonalcoholic steatohepatitis, but rather as a distinct disease.
authors.affiliation: Department of Surgery, University of Illinois, Chicago, Illinois.
authors.forename: Alan L
authors.initials: AL
authors.lastname: Buchman
authors.affiliation: Department of Pathology, UCLA Medical Center, Los Angeles, California.
authors.forename: Bita V
authors.initials: BV
authors.lastname: Naini
authors.affiliation: Bert Spilker and Associates LLC, Bethesda, Maryland.
authors.forename: Bert
authors.initials: B
authors.lastname: Spilker
mesh_terms: D018450:Disease Progression; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D008286:Malabsorption Syndromes / Q000150:complications* / Q000473:pathology; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D012307:Risk Factors