title: Oral Rehabilitation of a Patient With Ectodermal Dysplasia Treated With Fresh-Frozen Bone Allografts and Computer-Guided Implant Placement: A Clinical Case Report.
abstract: Ectodermal dysplasia (ED) is an inherited disorder characterized by abnormality of ectodermally derived structures. A recurrent oral finding is oligodontia, which in turn leads to a severely hypotrophic alveolar process with typical knife-edge morphology and adverse ridge contours. This unfavorable anatomy can seriously hamper proper implant placement. Fresh-frozen bone (FFB) allografts recently have been proposed to augment the residual bone volume for implant placement purposes; however, scientific evidence concerning the use of FFB to treat ED patients is absent. Similarly, data reporting computer-aided template-guided implant placement in medically compromised patients are limited. Thus the purpose of this report is to illustrate the oral rehabilitation of a female patient affected by ED and treated with appositional FFB block grafts and consecutive computer-guided flapless implant placement in a 2-stage procedure. Fixed implant-supported dental prostheses were finally delivered to the patient, which improved her self-esteem and quality of life. During the follow-up recall 1 year after the prosthetic loading, the clinical examination showed healthy peri-implant soft tissues with no signs of bleeding on probing or pathologic probing depths. The panoramic radiograph confirmed the clinical stability of the result. Peri-implant marginal bone levels were radiographically stable with neither pathologic bone loss at the mesial and distal aspects of each implant nor peri-implant radiolucency. Within the limitations of this report, the use of FFB allografts in association with computer-aided flapless implant surgery might be considered a useful technique in patients affected by ED.
authors.affiliation: Full Professor and Chairman, Oral Surgery and Implant Center for Maxillary Atrophies, School of Dentistry, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Maiorana
authors.affiliation: Fellow in Oral Sciences, Implant Center for Edentulism and Jawbone Atrophies, Maxillo-Facial and Odontostomatology Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy. Electronic address: pierpaolo.poli@unimi.it.
authors.forename: Pier Paolo
authors.initials: PP
authors.lastname: Poli
authors.affiliation: Clinical Assistant Professor, Implant Center for Edentulism and Jawbone Atrophies, Maxillo-Facial and Odontostomatology Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Poggio
authors.affiliation: Resident Doctor, Implant Center for Edentulism and Jawbone Atrophies, Maxillo-Facial and Odontostomatology Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Barbieri
authors.affiliation: Clinical Assistant Professor, Implant Center for Edentulism and Jawbone Atrophies, Maxillo-Facial and Odontostomatology Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Beretta
mesh_terms: D000328:Adult; D000848:Anodontia / Q000209:etiology* / Q000534:rehabilitation / Q000601:surgery*; D016025:Bone Transplantation; D003758:Dental Implantation, Endosseous; D004476:Ectodermal Dysplasia / Q000150:complications*; D005260:Female; D005615:Freezing; D006801:Humans; D025321:Surgery, Computer-Assisted