title: Vaginoplasty with an Autologous Buccal Mucosa Fenestrated Graft in Two Patients with Vaginal Agenesis: A Multidisciplinary Approach and Literature Review.
abstract: Here we describe the procedure and outcomes of a multidisciplinary approach to vaginoplasty using autologous buccal mucosa fenestrated grafts in 2 patients with vaginal agenesis. This procedure resulted in anatomic success, with a functional neovagina with good vaginal length and caliber and satisfactory sexual function capacity and well-healed buccal mucosa. There were no complications, and the patients were satisfied with the surgical results. We conclude that the use of a single fenestrated graft of autologous buccal mucosa is a simple, effective procedure for the treatment of vaginal agenesis that results in an optimally functioning neovagina with respect to vaginal length, caliber, and sexual capacity.
authors.affiliation: Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address: jessicachanmd@gmail.com.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Chan
authors.affiliation: Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Pamela J
authors.initials: PJ
authors.lastname: Levin
authors.affiliation: Department of Oral and Maxillofacial Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Brian P
authors.initials: BP
authors.lastname: Ford
authors.affiliation: Department of Oral and Maxillofacial Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: David C
authors.initials: DC
authors.lastname: Stanton
authors.affiliation: Center for Reproductive Medicine, Weill Cornell Medical College, New York, New York.
authors.forename: Samantha M
authors.initials: SM
authors.lastname: Pfeifer
mesh_terms: D000293:Adolescent; D000013:Congenital Abnormalities / Q000601:surgery*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D009061:Mouth Mucosa / Q000637:transplantation*; D014621:Vagina / Q000002:abnormalities* / Q000601:surgery; D055815:Young Adult
keywords: Mayer–Rokitansky–Küster–Hauser syndrome; Neovagina