title: The prevalence, risk factors and clinical correlates of obesity in Chinese patients with schizophrenia.
abstract: Obesity is a common comorbidity in schizophrenia. Few studies have addressed obesity in Chinese schizophrenia patients. The aims of this current study were to evaluate the prevalence, risk factors and clinical correlates of obesity in Chinese patients with schizophrenia. A total of 206 patients were recruited from a hospital in Beijing. Their clinical and anthropometric data together with plasma glucose and lipid parameters were collected. Positive and Negative Syndrome Scale (PANSS) was rated for all patients. Overall, 43 (20.9%) patients were obese and 67 (32.5%) were overweight. The obese patients had significantly higher glucose levels, triglyceride levels than non-obese patients. Females and patients with type 2 diabetes mellitus had increased risk for obesity. Correlation analysis showed that BMI was associated with sex, education levels, negative symptoms, total PANSS score, triglyceride levels and type 2 diabetes mellitus. Further stepwise regression analysis showed that sex, type 2 diabetes, education level, triglyceride and amount of smoking/day were significant predictors for obesity. Our study showed that the prevalence of obesity in Chinese patients with schizophrenia is higher than that in the general population. Some demographic and clinical variables are risk factors for obesity in schizophrenia.
authors.affiliation: Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Jiangsu, China; Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
authors.forename: Qiongzhen
authors.initials: Q
authors.lastname: Li
authors.affiliation: Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Jiangsu, China.
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Du
authors.affiliation: Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Jiangsu, China.
authors.forename: Yingyang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Jiangsu, China.
authors.forename: Guangzhong
authors.initials: G
authors.lastname: Yin
authors.affiliation: Suzhou Psychiatric Hospital, The Affiliated Guangji Hospital of Soochow University, Jiangsu, China.
authors.forename: Guangya
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
authors.forename: Consuelo
authors.initials: C
authors.lastname: Walss-Bass
authors.affiliation: Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
authors.forename: João
authors.initials: J
authors.lastname: Quevedo
authors.affiliation: Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
authors.forename: Jair C
authors.initials: JC
authors.lastname: Soares
authors.affiliation: Hefei Fourth People's Hospital, Anhui Mental Health Center, Hefei, China.
authors.forename: Haishen
authors.initials: H
authors.lastname: Xia
authors.affiliation: Hefei Fourth People's Hospital, Anhui Mental Health Center, Hefei, China.
authors.forename: Xiaosi
authors.initials: X
authors.lastname: Li
authors.affiliation: The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.
authors.forename: Yingjun
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Ning
authors.affiliation: Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA; Psychiatry Research Center, Beijing HuiLongGuan Hospital, Beijing, China. Electronic address: xiangyangzhang99@163.com.
authors.forename: Xiang Yang
authors.initials: XY
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry / Q000379:methods; D044466:Asian People / Q000523:psychology; D001786:Blood Glucose / Q000378:metabolism; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000453:epidemiology* / Q000523:psychology; D050177:Overweight / Q000097:blood / Q000453:epidemiology / Q000523:psychology; D015995:Prevalence; D012307:Risk Factors; D012559:Schizophrenia / Q000097:blood* / Q000453:epidemiology*; D012565:Schizophrenic Psychology; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D014280:Triglycerides
keywords: BMI; Chinese; Obesity; PANSS; Schizophrenia