title: Bridging the Gap in Peripheral Nerve Repair.
abstract: Peripheral nerve injuries following trauma present an ongoing challenge to the hand surgeon. This review presents an overview of the topic with a historical perspective. Nerve anatomy and nerve injury classifications are discussed followed by a description of the biology of nerve regeneration. Methods used to bridge gaps in peripheral nerve repair are discussed in detail with a critical appraisal of the most recent literature. Recommendations for surgical treatment are formulated based on evidence-based medicine.
authors.forename: Donato
authors.initials: D
authors.lastname: Perretta
authors.forename: Steven
authors.initials: S
authors.lastname: Green
mesh_terms: D000818:Animals; D019317:Evidence-Based Medicine; D006801:Humans; D009416:Nerve Regeneration; D019635:Neurosurgical Procedures / Q000009:adverse effects; D059348:Peripheral Nerve Injuries / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D010525:Peripheral Nerves / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome