title: Asymmetric hydroarylation of vinyl ethers catalyzed by a hydroxoiridium complex: azoles as effective directing groups.
abstract: Catalytic asymmetric hydroarylation of vinyl ethers using 2-aryl-substituted azoles containing an N-H bond as directing groups was realized by use of a hydroxoiridium/chiral phosphine catalyst. The reaction proceeded via C-H activation of the aromatic ring to give high yields of the corresponding addition products with high branch- and enantioselectivity.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. tnishi@kuchem.kyoto-u.ac.jp.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yamauchi
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. tnishi@kuchem.kyoto-u.ac.jp.
authors.forename: Takahiro
authors.identifier: http://orcid.org/0000-0002-7032-8613
authors.initials: T
authors.lastname: Nishimura
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. tnishi@kuchem.kyoto-u.ac.jp.
authors.forename: Hideki
authors.identifier: http://orcid.org/0000-0002-0153-1888
authors.initials: H
authors.lastname: Yorimitsu