title: Nanomedicine applied to cardiovascular diseases: latest developments.
abstract: Cardiovascular diseases are a major cause of disability and they are currently responsible for a significant number of deaths in a large percentage of the world population. A large number of therapeutic options have been developed for the management of cardiovascular diseases. However, they are insufficient to stop or significantly reduce the progression of these diseases, and may produce unpleasant side effects. In this situation, the need arises to continue exploring new technologies and strategies in order to overcome the disadvantages and limitations of conventional therapeutic options. Thus, treatment of cardiovascular diseases has become one of the major focuses of scientific and technological development in recent times. More specifically, there have been important advances in the area of nanotechnology and the controlled release of drugs, destined to circumvent many limitations of conventional therapies for the treatment of diseases such as hyperlipidemia, hypertension, myocardial infarction, stroke and thrombosis.
authors.affiliation: Instituto de Investigaciones en Ciencias Químicas, Facultad de Ciencias de la Alimentación, Bioquímicas y Farmacéuticas, Universidad Católica de Cuyo, Sede San Juan, Argentina.
authors.forename: Virna Margarita
authors.initials: VM
authors.lastname: Martín Giménez
authors.affiliation: Instituto de Investigaciones en Ciencias Químicas, Facultad de Ciencias de la Alimentación, Bioquímicas y Farmacéuticas, Universidad Católica de Cuyo, Sede San Juan, Argentina.
authors.forename: Diego E
authors.initials: DE
authors.lastname: Kassuha
authors.affiliation: Instituto de Medicina y Biología Experimental de Cuyo, Consejo Nacional de Investigación Científica y Tecnológica (IMBECU-CONICET), Argentina.|Laboratorio de Farmacología Experimental Básica y Traslacional, Área de Farmacología, Departamento de Patología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Centro Universitario, CP 5500, Mendoza, Argentina.
authors.forename: Walter
authors.initials: W
authors.lastname: Manucha
mesh_terms: D000818:Animals; D002309:Cardiology / Q000639:trends*; D002317:Cardiovascular Agents / Q000009:adverse effects / Q000737:chemistry / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000188:drug therapy*; D003692:Delayed-Action Preparations; D004059:Diffusion of Innovation; D004337:Drug Carriers; D004339:Drug Compounding; D006801:Humans; D050997:Nanomedicine / Q000639:trends*; D053758:Nanoparticles; D013678:Technology, Pharmaceutical / Q000639:trends*
chemical_list: D002317:Cardiovascular Agents; D003692:Delayed-Action Preparations; D004337:Drug Carriers
keywords: cardiovascular disease; controlled release of drugs; nanomedicine; nanotechnology