title: Docetaxel Retinopathy: A Case Report.
abstract: BACKGROUND
  To report the use of En-face optical coherence tomography (OCT) in a patient treated with docetaxel and tamoxifen for breast cancer for the detection of macular edema (ME) without evidence of leakage on fluorescein angiography (FA).
  
  
  METHODS
  A 52-year-old woman treated for breast cancer presented with bilateral visual loss for 2 months. FA showed no significant leakage while spectral-domain OCT scans of both eyes showed foveolar and parafoveolar cystic spaces in a moderately thickened macula. En-face OCT segmented at the inner retina showed the petaloid arrangement of cystic cavities, comparable to a cystoid ME.
  
  
  CONCLUSIONS
  The combined use of tamoxifen could have potentiated the toxic effect of docetaxel on the macula. En-face OCT images may reveal a petaloid aspect of the macula due to cysts in the inner retina segmentation, when FA shows no leakage.
authors.affiliation: Centre d'Imagerie et de Laser, Paris, France; Ophthalmology Department, Vision and Handicaps, Avicenne Hospital, Bobigny, France.
authors.forename: Sylvia
authors.initials: S
authors.lastname: Nghiem-Buffet
authors.affiliation: Ophthalmology Department, Vision and Handicaps, Avicenne Hospital, Bobigny, France.
authors.forename: Salomon Yves
authors.initials: SY
authors.lastname: Cohen
authors.affiliation: Centre d'Imagerie et de Laser, Paris, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Giocanti-Auregan
keywords: En-face OCT; Macular edema; Tamoxifen; Taxanes; Toxic retinopathy