title: Whole-body MRI in pediatric patients with cancer.
abstract: Cancer is the leading cause of natural death in the pediatric populations of developed countries, yet cure rates are greater than 70% when a cancer is diagnosed in its early stages. Recent advances in magnetic resonance imaging methods have markedly improved diagnostic and therapeutic approaches, while avoiding the risks of ionizing radiation that are associated with most conventional radiological methods, such as computed tomography and positron emission tomography/computed tomography. The advent of whole-body magnetic resonance imaging in association with the development of metabolic- and function-based techniques has led to the use of whole-body magnetic resonance imaging for the screening, diagnosis, staging, response assessment, and post-therapeutic follow-up of children with solid sporadic tumours or those with related genetic syndromes. Here, the advantages, techniques, indications, and limitations of whole-body magnetic resonance imaging in the management of pediatric oncology patients are presented.
authors.affiliation: Department of Imaging, AC Camargo Cancer Center, Rua Prof. Antônio Prudente, 211, Liberdade, São Paulo/SP, 01509-010, Brazil.|Universidade Federal do Vale do São Francisco (UNIVASF), Av. José de Sá Maniçoba, Petrolina, PE, 56304-917, Brazil.
authors.forename: Marcos Duarte
authors.initials: MD
authors.lastname: Guimarães
authors.affiliation: Department of Imaging, AC Camargo Cancer Center, Rua Prof. Antônio Prudente, 211, Liberdade, Sao Paulo/SP, 01509-010, Brazil. julia_noschang@hotmail.com.
authors.forename: Julia
authors.initials: J
authors.lastname: Noschang
authors.affiliation: Division of Radiology, Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto/ SP, 14049-090, Brazil.
authors.forename: Sara Reis
authors.initials: SR
authors.lastname: Teixeira
authors.affiliation: Division of Radiology, Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto/ SP, 14049-090, Brazil.
authors.forename: Marcel Koenigkam
authors.initials: MK
authors.lastname: Santos
authors.affiliation: Universidade Federal de São Paulo, Departamento de Diagnóstico Por Imagem, Disciplina de Diagnóstico por Imagem em Pediatria, Rua Napoleão de Barros, 800, Vila Clementino, Sao Paulo/SP, 04024002, Brazil.
authors.forename: Henrique Manoel
authors.initials: HM
authors.lastname: Lederman
authors.affiliation: Universidade Federal de São Paulo, Centro de Diagnóstico por Imagem do Instituto de Oncologia Pediátrica e Médica Radiologista do Centro de Diagnóstico por Imagem do Instituto de Oncologia Pediátrica, Rua Napoleão de Barros, 800, Vila Clementino, Sao Paulo/SP, 04024002, Brazil.
authors.forename: Vivian
authors.initials: V
authors.lastname: Tostes
authors.affiliation: Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
authors.forename: Vikas
authors.initials: V
authors.lastname: Kundra
authors.affiliation: Department of Imaging, AC Camargo Cancer Center, Rua Prof. Antônio Prudente, 211, Liberdade, Sao Paulo/SP, 01509-010, Brazil.
authors.forename: Alex Dias
authors.initials: AD
authors.lastname: Oliveira
authors.affiliation: Department of Radiology, Universidade Federal de Ciências da Saúde de Porto Alegre, Rua Professor Anes Dias, 285, Centro Histórico, Porto Alegre/RS, 90020-090, Brazil.
authors.forename: Bruno
authors.initials: B
authors.lastname: Hochhegger
authors.affiliation: Department of Radiology, Universidade Federal do Rio de Janeiro, Rua Thomaz Cameron, 438, Valparaíso, Petrópolis/RJ, 25685-129, Brazil.
authors.forename: Edson
authors.initials: E
authors.lastname: Marchiori
mesh_terms: D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009367:Neoplasm Staging; D009369:Neoplasms / Q000000981:diagnostic imaging*; D010372:Pediatrics; D051598:Whole Body Imaging / Q000379:methods*
keywords: Magnetic resonance imaging; Neoplasm; Pediatrics; Whole body MRI; Whole body imaging