title: [Clinical evaluation of periodontal-orthodontic treatment in patients with aggressive periodontitis and malocclusion].
abstract: To evaluate the clinical effect and safety of periodontal-orthodontic treatment in patients with aggressive periodontitis (AgP) and malocclusion.
  
  
  
  A retrospective analysis was conducted in 25 AgP patients, who had received periodontal-orthodontic treatment in Peking University School and Hospital of Stomatology. Clinical indexes, including probing depth (PD), bleeding index (BI) and percentage of sites with bleeding on probing (BOP%) were evaluated at three time points: Baseline (T0); active periodontal treatment finished and before orthodontic treatment (T1); and after orthodontic treatment (T2). Also changes of ratio of the residual alveolar bone height (RBH) and the occurrence of root resorption were evaluated by periapical radiographs.
  
  
  
  (1) Compared with T0, all the clinical parameters including PD, BI, BOP% and percentage of sites with PD>3 mm were significantly improved (P<0.001). (2) Significant difference was observed in the average RBH between T0 (68.37%±15.60% and T2 (70.27%±14.23%). RBH in upper incisors [(58.79%±16.71% at T0, 65.54% (55.74%, 78.13%) at T2], upper canines [77.62% (66.06%, 87.17%) at T0, 79.57% (69.75%, 86.52%) at T2] and upper molars [74.30% (61.69%, 84.45%) at T0, 76.76% (68.12%, 85.09%) at T2] showed significant increase (P<0.05). (3) After orthodontic treatment, varying degrees of root resorption occurred in (23.94%±13.45%) of teeth per capita, among which the lower and upper incisors showed the highest incidence (68.48% and 65.31% in homogeneous teeth, respectively).
  
  
  
  After active periodontal treatment, orthodontic treatment in AgP patients had not aggravated inflammation and alveolar bone resorption; root resorption occurred in two-thirds of incisors approximately.
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
authors.forename: X
authors.initials: X
authors.lastname: Shen
authors.affiliation: Department of Orthodontics, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
authors.forename: J
authors.initials: J
authors.lastname: Shi
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
authors.forename: L
authors.initials: L
authors.lastname: Xu
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
authors.forename: J
authors.initials: J
authors.lastname: Jiao
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
authors.forename: R F
authors.initials: RF
authors.lastname: Lu
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
authors.forename: H X
authors.initials: HX
authors.lastname: Meng
mesh_terms: D010520:Aggressive Periodontitis / Q000150:complications* / Q000628:therapy*; D016301:Alveolar Bone Loss / Q000209:etiology* / Q000517:prevention & control*; D000539:Alveolar Process / Q000254:growth & development / Q000473:pathology; D003481:Cuspid / Q000473:pathology; D006801:Humans; D007180:Incisor / Q000473:pathology; D008310:Malocclusion / Q000628:therapy*; D008963:Molar / Q000473:pathology; D009971:Orthodontics, Corrective / Q000009:adverse effects* / Q000706:statistics & numerical data; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000473:pathology / Q000628:therapy; D010517:Periodontics / Q000379:methods / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012391:Root Resorption / Q000209:etiology / Q000473:pathology; D016896:Treatment Outcome