title: The Inpatient Burden of Autoimmune Blistering Disease in US Children: Analysis of Nationwide Inpatient Sample Data.
abstract: BACKGROUND
  Little is known about the epidemiology of pediatric autoimmune blistering disorders (PAIBD).
  
  
  OBJECTIVE
  We sought to determine the inpatient burden and comorbidities of PAIBD.
  
  
  METHODS
  We analyzed data from the Nationwide Inpatient Sample from 2002 to 2012, which contained a representative 20% sample of all US hospitalizations.
  
  
  RESULTS
  The most common PAIBD with a primary admission was pemphigus (8.0 per million), whereas the most common secondary diagnosis of PAIBD was dermatitis herpetiformis (DH; 9.6 per million). Bullous pemphigoid (BP) was inversely associated with being female and having government or no insurance but positively associated with Black and Hispanic race/ethnicity and more chronic conditions. Pemphigus was associated with being female, Hispanic, having government or no insurance, and having a higher number of chronic conditions. DH was inversely associated with non-White race but positively associated with having government insurance and more chronic conditions. BP was associated with dialysis, hypertension, and diabetes. Pemphigus was associated with osteoarthritis, renal failure, hypothyroidism, and weight loss. DH was associated with herpes simplex virus infection, rheumatoid arthritis, and fungal, viral, and other skin infections.
  
  
  CONCLUSIONS
  PAIBD are associated with a considerable inpatient burden and comorbid health conditions.
authors.affiliation: Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.|The Graduate School, Northwestern University, Chicago, IL, 60611, USA.
authors.forename: Ziyou
authors.initials: Z
authors.lastname: Ren
authors.affiliation: Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
authors.forename: Derek Y
authors.initials: DY
authors.lastname: Hsu
authors.affiliation: Department of Dermatology, Mount-Sinai Icahn School of Medicine, New York, NY, USA.
authors.forename: Nanette B
authors.initials: NB
authors.lastname: Silverberg
authors.affiliation: Departments of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Suite 1600, 676 N. St. Clair St., Chicago, IL, 60611, USA. JonathanISilverberg@Gmail.com.
authors.forename: Jonathan I
authors.initials: JI
authors.lastname: Silverberg
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D017281:Cost of Illness; D003874:Dermatitis Herpetiformis / Q000191:economics* / Q000453:epidemiology*; D005260:Female; D006760:Hospitalization / Q000191:economics*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male; D010391:Pemphigoid, Bullous / Q000191:economics* / Q000453:epidemiology*; D010392:Pemphigus / Q000191:economics* / Q000453:epidemiology*; D012737:Sex Factors; D014481:United States / Q000453:epidemiology