title: Decarbonylative Diaryl Ether Synthesis by Pd and Ni Catalysis.
abstract: Because diaryl ethers are present as an important motif in pharmaceuticals and natural products, extensive studies for the development of novel methods have been conducted. A conventional method for the construction of the diaryl ether moiety is the intermolecular cross-coupling reaction of aryl halides and phenols with a copper or palladium catalyst. We developed a catalytic decarbonylative etherification of aromatic esters using a palladium or nickel catalyst with our enabling diphosphine ligand to give the corresponding diaryl ethers. The present reaction can be conducted on gram scale in excellent yield. This reaction not only functions in an intramolecular setting but also allows for a cross-etherification using other phenols.
authors.affiliation: Institute of Transformative Bio-Molecules (WPI-ITbM) and Graduate School of Science, Nagoya University , Chikusa, Nagoya 464-8602, Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Takise
authors.affiliation: Department of Applied Chemistry, Waseda University , 3-4-1 Ohkubo, Shinjuku, Tokyo 169-8555, Japan.
authors.forename: Ryota
authors.initials: R
authors.lastname: Isshiki
authors.affiliation: Department of Applied Chemistry, Waseda University , 3-4-1 Ohkubo, Shinjuku, Tokyo 169-8555, Japan.
authors.forename: Kei
authors.identifier: 0000-0001-8301-4384
authors.initials: K
authors.lastname: Muto
authors.affiliation: Institute of Transformative Bio-Molecules (WPI-ITbM) and Graduate School of Science, Nagoya University , Chikusa, Nagoya 464-8602, Japan.|JST-ERATO, Itami Molecular Nanocarbon Project, Nagoya University , Chikusa, Nagoya 464-8602, Japan.
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
authors.affiliation: Department of Applied Chemistry, Waseda University , 3-4-1 Ohkubo, Shinjuku, Tokyo 169-8555, Japan.
authors.forename: Junichiro
authors.identifier: 0000-0002-3896-5882
authors.initials: J
authors.lastname: Yamaguchi