title: [Diagnostics of clinical and prodromal idiopathic Parkinson's disease : New criteria].
abstract: BACKGROUND
  Recently, the Movement Disorder Society (MDS) published an adaptation of the previous United Kingdom Brain Bank Society (UKBBS) criteria for the diagnosis of idiopathic Parkinson's disease (iPD).
  
  
  OBJECTIVE
  This article presents the changes in the current clinical diagnostic criteria for IPD. Furthermore, the new MDS criteria for prodromal iPD are discussed.
  
  
  RESULTS
  The recently introduced MDS criteria for the clinical diagnosis of iPD include useful novel features (e.g. postural instability is no longer listed as a cardinal symptom, familiar history of iPD and intake of neuroleptics at the first visit no longer lead to exclusion of the diagnosis) and red flags do not lead to exclusion of the diagnosis; however, they must be counterbalanced by the presence of supportive criteria for iPD. The criteria for identification of persons in the prodromal stage are currently established only for scientific investigations.
  
  
  CONCLUSIONS
  The new MDS criteria for the diagnostics of iPD should help to improve the sensitivity and specificity.
authors.affiliation: Universitätsklinik für Neurologie, Medizinische Universität Wien, Wien, Österreich.|Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Centre, Nijmegen, Niederlande.
authors.forename: H
authors.initials: H
authors.lastname: Zach
authors.affiliation: Klinik und Poliklinik für Neurologie, Universitätsmedizin Rostock, Rostock, Deutschland.
authors.forename: U
authors.initials: U
authors.lastname: Walter
authors.affiliation: Hertie Institut für klinische Hirnforschung, Universität Tübingen und Deutsches Zentrum für Neurodegenerative Erkrankungen, Tübingen, Deutschland.
authors.forename: I
authors.initials: I
authors.lastname: Liepelt-Scarfone
authors.affiliation: Klinik für Neurologie, Universitätsklinikum Schleswig-Holstein, Arnold-Heller-Straße 3, 24105, Kiel, Deutschland. w.maetzler@neurologie.uni-kiel.de.
authors.forename: W
authors.initials: W
authors.lastname: Maetzler
mesh_terms: D003937:Diagnosis, Differential; D003943:Diagnostic Techniques, Neurological / Q000592:standards*; D019317:Evidence-Based Medicine; D006801:Humans; D009069:Movement Disorders / Q000150:complications / Q000175:diagnosis*; D009462:Neurology / Q000592:standards*; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis*; D010808:Physical Examination / Q000592:standards*; D017410:Practice Guidelines as Topic; D062706:Prodromal Symptoms; D006113:United Kingdom
keywords: Bradykinesia; Movement disorders; Neuroleptics; Postural stability; Tremor