title: Cancer cell cannibalism and the SASP: Ripples in the murky waters of tumor dormancy.
abstract: Relapse in cancer patients following an apparent cure and a prolonged latency period, known as tumor dormancy, remains an unrelenting clinical crisis. Here, I expand on our recent findings that potentially link cancer cell cannibalism of bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) to the senescence-associated secretory phenotype (SASP) and tumor dormancy.
authors.affiliation: Medical Physiology, College of Medicine, Texas A&M University System Health Science Center, Temple, TX, USA; Institute for Regenerative Medicine, College of Medicine, Texas A&M University System Health Science Center, Temple, TX, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Bartosh
keywords: Cancer; MSC; SASP; cell cannibalism; inflammation; senescence; tumor dormancy