title: The Use of Functionalized Silk Fibroin Films as a Platform for Optical Diffraction-Based Sensing Applications.
abstract: A set of biocompatible, biodegradable, and biofunctionalizable diffractive optical elements (DOEs) using silk proteins as the building materials is reported. The diffraction pattern of a DOE is highly sensitive to the surrounding environment and the structural integrity, offering numerous opportunities for biosensing applications.
authors.affiliation: State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.|School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Zhitao
authors.initials: Z
authors.lastname: Zhou
authors.affiliation: Department of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040, China.
authors.forename: Zhifeng
authors.initials: Z
authors.lastname: Shi
authors.affiliation: State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.|School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Cai
authors.affiliation: Department of Mechanical Engineering, the University of Texas at Austin, Austin, TX, 78712, USA.
authors.forename: Shaoqing
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794, USA.
authors.forename: Stephanie G
authors.initials: SG
authors.lastname: Corder
authors.affiliation: State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.|School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049, China.|School of Physical Science and Technology, ShanghaiTech University, Shanghai, 200031, China.
authors.forename: Xinxin
authors.initials: X
authors.lastname: Li
authors.affiliation: Sericultural Research Institute College of Biotechnology, Jiangsu University of Science and Technology, No.2 Mengxi Road, Zhenjiang, Jiangsu, 212003, China.
authors.forename: Yeshun
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Sericultural Research Institute College of Biotechnology, Jiangsu University of Science and Technology, No.2 Mengxi Road, Zhenjiang, Jiangsu, 212003, China.
authors.forename: Guozheng
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794, USA.
authors.forename: Mengkun
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of Biomedical Engineering, Tufts University, Medford, MA, 02155, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Kaplan
authors.affiliation: Department of Biomedical Engineering, Tufts University, Medford, MA, 02155, USA.
authors.forename: Fiorenzo G
authors.initials: FG
authors.lastname: Omenetto
authors.affiliation: Department of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Mao
authors.affiliation: Department of Medical Laboratory Medicine, Nanchang Hospital of Integrative Traditional Chinese and Western Medicine, Nanchang, Jiangxi, 330003, China.
authors.forename: Zhendong
authors.initials: Z
authors.lastname: Tao
authors.affiliation: State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.|School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049, China.|Department of Mechanical Engineering, the University of Texas at Austin, Austin, TX, 78712, USA.|School of Physical Science and Technology, ShanghaiTech University, Shanghai, 200031, China.
authors.forename: Tiger H
authors.initials: TH
authors.lastname: Tao
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D012831:Bombyx; D005349:Fibroins / Q000737:chemistry*; D055096:Optical Devices; D047011:Silk
chemical_list: D001672:Biocompatible Materials; D047011:Silk; D005349:Fibroins
keywords: bio-optics; diffractive optical element; microstructuring; silk fibroins