title: Ultrahigh-frequency ultrasound of fascicles in the median nerve at the wrist.
abstract: BACKGROUND
  An ultrahigh-frequency (70 MHZ) ultrasound device has recently been approved for human use. This study seeks to determine whether this device facilitates counting of fascicles within the median nerve at the wrist.
  
  
  METHODS
  Twenty healthy volunteers underwent imaging of the median nerve at the wrist bilaterally. The number of fascicles in each nerve was counted by two independent raters.
  
  
  RESULTS
  The mean fascicle number was 22.68. Correlation was strong between the two raters (r = 0.68, P < 0.001). Age, sex, body mass index, and nerve area did not predict fascicle number. Those with bifid median nerves and persistent median arteries had lower fascicle density than those without anatomic anomalies (1.79 vs. 2.29; P = 0.01).
  
  
  CONCLUSIONS
  Fascicles within the median nerve at the wrist can be readily imaged. Ultrahigh-frequency ultrasound technology may be informative in a variety of disorders affecting the peripheral nervous system. Muscle Nerve 56: 819-822, 2017.
authors.affiliation: Department of Neurology, Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC, USA, 27157.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Cartwright
authors.affiliation: Department of Neurology, Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC, USA, 27157.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Baute
authors.affiliation: Department of Neurology, Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC, USA, 27157.
authors.forename: James B
authors.initials: JB
authors.lastname: Caress
authors.affiliation: Department of Neurology, Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC, USA, 27157.
authors.forename: Francis O
authors.initials: FO
authors.lastname: Walker
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000000981:diagnostic imaging*; D008875:Middle Aged; D014463:Ultrasonography / Q000379:methods*; D014953:Wrist / Q000000981:diagnostic imaging* / Q000294:innervation*
keywords: carpal tunnel syndrome; fascicles; median nerve; motor neuron disease; polyneuropathy; ultrasound