title: An analysis of phosphorylation sites in protein kinases fromLeishmania.
abstract: Protein kinases are promising drug targets for Leishmaniasis. We have evaluated the phosphorylation potential of protein kinases in different species and strains of Leishmania. Phosphorylation potential of serine, threonine and tyrosine residues of kinases in Leishmania parasite were studied. The results indicate that some species specific residues of serine, threonine and tyrosine have a phosphorylation potential of 1 suggesting that these residues are important target sites in protein kinases based anti-leishmanial therapies.
authors.affiliation: Centre of Biotechnology, University of Allahabad, Allahabad, Uttar Pradesh - 211002 India.
authors.forename: Sukrat
authors.initials: S
authors.lastname: Sinha
authors.affiliation: Centre of Biotechnology, University of Allahabad, Allahabad, Uttar Pradesh - 211002 India.
authors.forename: Shanthy
authors.initials: S
authors.lastname: Sundaram
keywords: Kinases; Leishmania; Phosphorylation sites