title: Recovery of nail dystrophy potential new therapeutic indication of tofacitinib.
abstract: Nail dystrophy is a heterogeneous skin condition and in some subtypes, is associated with autoimmune diseases in particular psoriasis and psoriatic arthritis. In this report, we show that tofacitinib, a novel therapy for rheumatoid arthritis, appears to be beneficial in patients with nail disease refractory to other conventional modes of therapy.
authors.affiliation: Clinica de la Piel, Departamento de Dermatologia, Barranquilla, Colombia.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Jaller
authors.affiliation: Centro de Reumatologia y Ortopedia, Division de Reumatologia, Barranquilla, Colombia.
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Jaller
authors.affiliation: Clinica de la Piel, Departamento de Dermatologia, Barranquilla, Colombia.
authors.forename: Antonio M
authors.initials: AM
authors.lastname: Jaller
authors.affiliation: Centro de Reumatologia y Ortopedia, Division de Reumatologia, Barranquilla, Colombia.
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Jaller-Char
authors.affiliation: Clinica Dermatosineida, Maringá, Brazil.
authors.forename: Sineida Berbert
authors.initials: SB
authors.lastname: Ferreira
authors.affiliation: Clinica Dermatosineida, Maringá, Brazil.
authors.forename: Rachel
authors.initials: R
authors.lastname: Ferreira
authors.affiliation: Hospital Israelita Albert Einstein, Hospital AACD, São Paulo, Brazil. morton@osite.com.br.
authors.forename: Morton
authors.initials: M
authors.lastname: Scheinberg
mesh_terms: D000328:Adult; D000505:Alopecia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000188:drug therapy*; D010880:Piperidines / Q000008:administration & dosage*; D047428:Protein Kinase Inhibitors / Q000008:administration & dosage*; D011743:Pyrimidines / Q000008:administration & dosage*; D011758:Pyrroles / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D010880:Piperidines; D047428:Protein Kinase Inhibitors; D011743:Pyrimidines; D011758:Pyrroles; C479163:tofacitinib
keywords: Janus kinase; Nail dystrophy; Tofacitinib