title: Risk Factors for Recurrent Intussusception After Fluoroscopy-Guided Air Enema.
abstract: OBJECTIVE
  The aim of this study was to identify risk factors for recurrent intussusception after a successful reduction by fluoroscopy-guided air enema, the time required for recurrence, and the association between delayed reduction and the recurrence.
  
  
  METHODS
  Medical records of 479 consecutive children with intussusception who underwent fluoroscopy-guided air enema between January 2004 and September 2014 were reviewed. Recurrent intussusception was defined as a recurrence within 48 hours of a reduction. Symptom-to-door time was defined as the time from symptom onset to emergency department arrival. Door-to-reduction time was defined as the time from emergency department arrival to reduction. Time-to-recurrence was defined as the time required for recurrence from the first ultrasound diagnosis.
  
  
  RESULTS
  Of the 360 eligible children, 32 had recurrent intussusceptions (8.9%). Multivariable logistic regression showed that age 2 years or older is an independent predictor of recurrent intussusception (odds ratio, 2.39; 95% confidence interval, 1.13-5.02; P = 0.02). Median time to recurrence was 25 hours (18.0-36.0 hours). Although symptom-to-door and door-to-reduction times tended to be longer in the recurrence group, these differences were not significant (12.5 vs 7.0 hours, P = 0.18; 154.0 vs 143.0 minutes, P = 0.67, respectively).
  
  
  CONCLUSIONS
  Our data suggest that provision for early recurrence and extended observation may be beneficial for children 2 years or older. Delayed reduction was not associated with recurrent intussusception, but further studies with larger sample sizes are needed to explain this issue.
authors.affiliation: From the Departments of Pediatrics and.
authors.forename: Jung Heon
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Jong Seung
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Ryu
authors.affiliation: Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Kyoung Soo
authors.initials: KS
authors.lastname: Lim
authors.affiliation: Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Won Young
authors.initials: WY
authors.lastname: Kim
mesh_terms: D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004733:Enema / Q000009:adverse effects* / Q000379:methods; D005260:Female; D005471:Fluoroscopy / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007223:Infant; D007443:Intussusception / Q000628:therapy*; D008297:Male; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome