title: Levels of Intracellular Phosphorylated Tenofovir and Emtricitabine Correlate With Natural Substrate Concentrations in Peripheral Blood Mononuclear Cells of Persons Prescribed Daily Oral Truvada for HIV Pre-exposure Prophylaxis.
authors.affiliation: *Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA †Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Haaland
authors.forename: Angela
authors.initials: A
authors.lastname: Holder
authors.forename: Chou-Pong
authors.initials: CP
authors.lastname: Pau
authors.forename: Alison
authors.initials: A
authors.lastname: Swaims-Kohlmeier
authors.forename: Carolyn
authors.initials: C
authors.lastname: Dawson
authors.forename: Dawn K
authors.initials: DK
authors.lastname: Smith
authors.forename: Tebogo M
authors.initials: TM
authors.lastname: Segolodi
authors.forename: Michael C
authors.initials: MC
authors.lastname: Thigpen
authors.forename: Lynn A
authors.initials: LA
authors.lastname: Paxton
authors.forename: Teresa L
authors.initials: TL
authors.lastname: Parsons
authors.forename: Craig W
authors.initials: CW
authors.lastname: Hendrix
authors.forename: Clyde E
authors.initials: CE
authors.lastname: Hart
mesh_terms: D000328:Adult; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects*; D000069480:Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination / Q000493:pharmacokinetics*; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D010766:Phosphorylation; D065129:Pre-Exposure Prophylaxis; D018894:Reverse Transcriptase Inhibitors / Q000493:pharmacokinetics*; D013379:Substrate Specificity; D019562:Viral Load
chemical_list: D000069480:Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; D018894:Reverse Transcriptase Inhibitors; D054303:HIV Reverse Transcriptase