title: Ruthenium-Catalyzed [2 + 2 + 2] Cycloaddition Reaction Forming 2-Aminopyridine Derivatives from α,ω-Diynes and Cyanamides.
abstract: A novel, efficient, and mild synthetic route for the preparation of 2-aminopyridines via ruthenium-mediated [2 + 2 + 2] cycloaddition of α,ω-diynes and cyanamides has been developed. This atom-economical catalytic process demonstrated remarkable regioselectivities to access pyridine derivatives of high synthetic utility.
authors.affiliation: PSL Research University, Chimie ParisTech - CNRS , Institut de Recherche de Chimie Paris, Paris 75005, France.
authors.forename: Fei
authors.initials: F
authors.lastname: Ye
authors.affiliation: PSL Research University, Chimie ParisTech - CNRS , Institut de Recherche de Chimie Paris, Paris 75005, France.
authors.forename: Mansour
authors.initials: M
authors.lastname: Haddad
authors.affiliation: PSL Research University, Chimie ParisTech - CNRS , Institut de Recherche de Chimie Paris, Paris 75005, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Ratovelomanana-Vidal
authors.affiliation: PSL Research University, Chimie ParisTech - CNRS , Institut de Recherche de Chimie Paris, Paris 75005, France.
authors.forename: Véronique
authors.identifier: 0000-0002-2217-9115
authors.initials: V
authors.lastname: Michelet