title: Leukemia cutis in a patient with chronic lymphocytic leukemia presenting as bilateral helical nodules.
abstract: Chronic lymphocytic leukemia, the most common adult leukemia worldwide, is considered an indolent but incurable non-Hodgkin lymphoma. Leukemia cutis is an uncommon manifestation of chronic lymphocytic leukemia. We present a case of an adult patient who presented with skin lesion of bilateral ears, which led to the diagnosis of chronic lymphocytic leukemia. We also reviewed the cases of auricular involvement in chronic lymphocytic leukemia patients reported in the literature. Local treatment is indicated in case of leukemia cutis; however, systemic treatment is recommended when there are systemic signs and symptoms. Better awareness of disease evolution and prompt diagnosis of this leukemia cutis of chronic lymphocytic leukemia will improve the effectiveness and outcome of its management.
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, Joan C. Edwards School of Medicine, Marshall University-Edwards Comprehensive Cancer Center, Huntington, WV, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Raufi
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, Joan C. Edwards School of Medicine, Marshall University-Edwards Comprehensive Cancer Center, Huntington, WV, USA.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Alsharedi
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, Joan C. Edwards School of Medicine, Marshall University-Edwards Comprehensive Cancer Center, Huntington, WV, USA.
authors.forename: Yousef
authors.initials: Y
authors.lastname: Khelfa
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, Joan C. Edwards School of Medicine, Marshall University-Edwards Comprehensive Cancer Center, Huntington, WV, USA.
authors.forename: Doreen C
authors.initials: DC
authors.lastname: Griswold
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, Joan C. Edwards School of Medicine, Marshall University-Edwards Comprehensive Cancer Center, Huntington, WV, USA.
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Lebowicz
keywords: Chronic lymphocytic leukemia; ear involvement; leukemia cutis