title: Secondary Metabolites from Polar Organisms.
abstract: Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms, lichen, moss and marine faunas. The structures of the new compounds and details of the source organism, along with any relevant biological activities are presented. Where reported, synthetic and biosynthetic studies on the polar metabolites have also been included.
authors.affiliation: College of Life Science, Taishan Medical University, Taian 271016, Shandong, China. tianyuan2005hit@163.com.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Tian
authors.affiliation: College of Life Science, Taishan Medical University, Taian 271016, Shandong, China. lingl816@163.com.
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Li
authors.affiliation: College of Life Science, Shandong Agricultural University, Taian 271018, Shandong, China. zhaofengchun@126.com.
authors.forename: Feng-Chun
authors.initials: FC
authors.lastname: Zhao
mesh_terms: D000818:Animals; D000864:Antarctic Regions; D059001:Aquatic Organisms / Q000737:chemistry*; D001110:Arctic Regions; D001688:Biological Products / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008386:Marine Biology / Q000379:methods
chemical_list: D001688:Biological Products
keywords: biological activity; biosynthesis; chemical synthesis; natural products; secondary metabolism; structure elucidation