title: Effects of David I operation in the treatment of aortic root disease combined with aortic insufficiency.
abstract: BACKGROUND
  We compared the effects of the new David I operation and classical Bentall operation in the treatment of aortic root disease combined with aortic insufficiency.
  
  
  METHODS
  A total of 60 cases of patients with aortic root disease combined with aortic insufficiency diagnosed at our hospital from January 2010 to January 2016 were analyzed retrospectively, including 32 cases of aortic root aneurysm, 18 cases of aortic dissection, 5 cases of hypertension combined with atherosclerosis, 2 cases of retrogression, 2 cases of rheumatic heart disease and 1 case of Takayasu arteritis. Twenty-four cases that underwent the David I operation and 36 cases that underwent the Bentall operation were selected and their therapeutic effects were compared. The operation success rate, operation time, cardiopulmonary bypass time, cross-clamp time and blood infusion of both groups were compared; there were no significant differences (P>0.05).
  
  
  RESULTS
  Two patients in the David I group and 3 patients in the Bentall operation group died of multiple organ dysfunction. The LVEDd and LVEF of both groups postoperation had no difference when compared with those parameters of before operation. The diameter of the valve annulus after the operation was shorter than before the operation. The severity of valve regurgitation of both groups had no difference. However, the ratio of severe regurgitation of the David I group increased and the mild regurgitation decreased. The incidence rate of complications of the David I group was significantly lower than that of the Bentall operation group. The differences were statistically significant (P<0.05).
  
  
  CONCLUSIONS
  Both David I operation and Bentall operation have better short-term and long-term effects in the treatment of aortic root disease when combined with aortic insufficiency; however, David I operation had less long-term complications.
authors.affiliation: Department of Cardiothoracic Surgery, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China.
authors.forename: Ji-Dan
authors.initials: JD
authors.lastname: Fan
authors.affiliation: Department of Cardiothoracic Surgery, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China.
authors.forename: Yu-Sheng
authors.initials: YS
authors.lastname: Shu
authors.affiliation: The Second Xiangya Hospital of Central South University, Changsha, Hunan Province, China.
authors.forename: Xin-Min
authors.initials: XM
authors.lastname: Zhou
authors.affiliation: The Second Xiangya Hospital of Central South University, Changsha, Hunan Province, China.
authors.forename: Zhao-Shun
authors.initials: ZS
authors.lastname: Yuan
authors.affiliation: The Second Xiangya Hospital of Central South University, Changsha, Hunan Province, China.
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Liao
authors.affiliation: Department of Cardiothoracic Surgery, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China.
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Shi
authors.affiliation: Department of Cardiothoracic Surgery, Northern Jiangsu People's Hospital, Yangzhou, Jiangsu Province, China - ym86747832@163.com.
authors.forename: Min
authors.initials: M
authors.lastname: Yang
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000601:surgery; D001011:Aorta / Q000601:surgery*; D001014:Aortic Aneurysm / Q000601:surgery; D001018:Aortic Diseases / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000601:surgery*; D003331:Coronary Vessels / Q000601:surgery*; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology / Q000401:mortality; D059351:Organ Sparing Treatments; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D012092:Replantation; D012189:Retrospective Studies; D013318:Stroke Volume; D016896:Treatment Outcome