title: A Rare Case of Bilateral Optic Neuritis and Guillain-Barré Syndrome PostMycoplasma pneumoniaeInfection.
abstract: Neurological complications are the most commonly encountered extra-pulmonary manifestation of infection withMycoplasma pneumoniae (M. pneumoniae). Here the authors report the case of a 39-year-old woman who was admitted with acute-onset bilateral visual loss coinciding with ascending numbness. Clinical examination, neurological imaging, and nerve conduction studies revealed a syndrome of bilateral optic neuritis and Guillain-Barré syndrome (GBS). Serological testing confirmed recent exposure toM. pneumoniae. The patient did not experience any clinical benefit with pulsed intravenous methylprednisolone but demonstrated marked clinical and radiological improvement following 5 days of plasma exchange. This report will explore the diagnostic and therapeutic approach to patients with neuro-ophthalmological and neurological complications ofM. pneumoniaeinfection in addition to discussing previously encountered cases.
authors.affiliation: Department of Neurology, National Hospital for Neurology and Neurosurgery , London, United Kingdom.
authors.forename: Aravindhan
authors.initials: A
authors.lastname: Baheerathan
authors.affiliation: Department of Neurology, National Hospital for Neurology and Neurosurgery , London, United Kingdom.
authors.forename: Amy
authors.initials: A
authors.lastname: Ross Russell
authors.affiliation: Department of Neuro-ophthalmology, National Hospital for Neurology and Neurosurgery , London, United Kingdom.
authors.forename: Fion
authors.initials: F
authors.lastname: Bremner
authors.affiliation: Department of Neurology, National Hospital for Neurology and Neurosurgery , London, United Kingdom.
authors.forename: Simon F
authors.initials: SF
authors.lastname: Farmer
keywords: Guillain-Barré syndrome; Mycoplasma pneumoniae; optic neuritis; plasma exchange; post-infectious inflammatory neuropathy; post-infectious optic neuropathy