title: Point-of-care monitoring for the management of trauma-induced bleeding.
abstract: OBJECTIVE
  Knowledge of trauma-induced coagulopathy has been grown in the past and point-of-care suitable devices for coagulation testing have been introduced. Methodology and clinical application of different systems for point-of-care coagulation monitoring are shown with a focus on thrombelastography as measured by TEG, rotational thromboelastometry as measured by ROTEM and impedance aggregometry as measured by the multiplate analyser and ROTEM platelet.
  
  
  RESULTS
  Two different methods for point-of-care coagulation assessment are available: viscoelastic tests (ROTEM, TEG) and impedance aggregometry. In different settings these methods have been evaluated in various publications pointing out the possibility of reducing transfusion requirements, transfusion-related side effects, and resulting costs.
  
  
  CONCLUSIONS
  Point-of-care assessment of coagulation in trauma patients appears to be at least promising. However, because published data mostly are of retrospective or observational nature only, there is a need for prospective, randomized and controlled studies.
authors.affiliation: aKlinik für Anästhesiologie und Intensivmedizin, Medizinische Hochschule Hannover, Hannover bKlinik für Orthopädie, Diakovere Annastift cKlinik für Unfallchirurgie, Medizinische Hochschule Hannover, Hannover, Germany.
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Hanke
authors.forename: Hauke
authors.initials: H
authors.lastname: Horstmann
authors.forename: Michaela
authors.initials: M
authors.lastname: Wilhelmi
mesh_terms: D001778:Blood Coagulation Disorders / Q000175:diagnosis* / Q000209:etiology; D001780:Blood Coagulation Tests / Q000295:instrumentation / Q000379:methods*; D001803:Blood Transfusion; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods*; D019095:Point-of-Care Systems; D014947:Wounds and Injuries / Q000150:complications* / Q000628:therapy