title: Colonic Schwannoma: A Case Study and Literature Review of a Rare Entity and Diagnostic Dilemma.
abstract: An asymptomatic 73-year-old woman was found to have a submucosal mass in the descending colon on routine colonoscopy. A CT scan revealed a 31 × 28 × 31 mm lesion in the same location. Previous biopsy proved to be nondiagnostic, and the patient underwent a laparoscopic descending colon resection. Histologic evaluation of the tumor revealed a low grade spindle cell neoplasm with strong, diffuse positivity for S-100 protein by immunohistochemistry, leading to the diagnosis of schwannoma. A review of the literature revealed intestinal schwannoma to be a rare disease entity, with only about 50 cases previously reported.
authors.affiliation: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
authors.forename: Alex
authors.initials: A
authors.lastname: Uhr
authors.forename: Awinder P
authors.initials: AP
authors.lastname: Singh
authors.forename: Jose
authors.initials: J
authors.lastname: Munoz
authors.forename: Allison
authors.initials: A
authors.lastname: Aka
authors.forename: Melanie
authors.initials: M
authors.lastname: Sion
authors.forename: Wei
authors.initials: W
authors.lastname: Jiang
authors.forename: Scott D
authors.initials: SD
authors.lastname: Goldstein
authors.forename: Ernest L
authors.initials: EL
authors.lastname: Rosato
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D003110:Colonic Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000473:pathology; D003113:Colonoscopy; D005260:Female; D006801:Humans; D009442:Neurilemmoma / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000473:pathology; D035583:Rare Diseases / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor