title: Thermolysis and radiofluorination of diaryliodonium salts derived from anilines.
abstract: Aniline-derived diaryliodonium salts were synthesized and functionalized in good to excellent yields by judicious utilization of electron-withdrawing protecting groups. This simple approach opens another route to radiolabeling amino arenes in relatively complex molecules, such as flutemetamol.
authors.affiliation: Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588, USA and Departments of Medicinal Chemistry & Pharmacognosy and Chemistry, University of Illinois-Chicago, Chicago, Illinois 60612, USA. sdimagno@uic.edu.
authors.forename: Ethan J
authors.initials: EJ
authors.lastname: Linstad
authors.affiliation: Division of Nuclear Medicine, Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
authors.forename: Amy L
authors.initials: AL
authors.lastname: Vāvere
authors.affiliation: Departments of Medicinal Chemistry & Pharmacognosy and Chemistry, University of Illinois-Chicago, Chicago, Illinois 60612, USA. sdimagno@uic.edu.
authors.forename: Bao
authors.initials: B
authors.lastname: Hu
authors.affiliation: Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588, USA.
authors.forename: Jayson J
authors.initials: JJ
authors.lastname: Kempinger
authors.affiliation: Division of Nuclear Medicine, Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
authors.forename: Scott E
authors.initials: SE
authors.lastname: Snyder
authors.affiliation: Departments of Medicinal Chemistry & Pharmacognosy and Chemistry, University of Illinois-Chicago, Chicago, Illinois 60612, USA. sdimagno@uic.edu.
authors.forename: Stephen G
authors.identifier: http://orcid.org/0000-0001-7861-4799
authors.initials: SG
authors.lastname: DiMagno