title: Silk textile with antimicrobial AEM5772/5 (Dermasilk): a pilot study with positive influence on acne vulgaris on the back.
abstract: BACKGROUND
  The use of special silk textiles (Dermasilk) has shown positive effects on chronic inflammatory diseases like lichen sclerosus et atrophicus, atopic dermatitis, diabetic ulcerations, and vulvovaginal candidiasis.
  
  
  OBJECTIVE
  Wearing T-shirts of this particular fabric could be useful in the management of patients with acne vulgaris on the back and trunk.
  
  
  METHODS
  Dermasilk T-shirts were given to 14 patients with acne vulgaris papulopustulosa on the back. The patients wore these shirts every night for 6 weeks, and their acne lesions were monitored. Dermasilk represents a polymerisate of fibroin, a silk protein, and antimicrobial AEM5772/5, an unsoluble colorless, odorless ammonium with antifungal and antibacterial ability.
  
  
  RESULTS
  Photographic documentation before and after 6 weeks showed a clinically significant reduction in acne lesions on the back without any concomitant treatment or change in lifestyle and living conditions.
  
  
  CONCLUSIONS
  The use of Dermasilk textiles in other subacute-chronic inflammatory skin diseases has shown positive effects. This is the first report on their safe and effective use in the management of acne vulgaris papulopustulosa corporis.
authors.affiliation: Center of Aesthetic Medicine, Department of Dermatology, Medical University Graz, Graz, Austria.
authors.forename: Caroline
authors.initials: C
authors.lastname: Schaunig
authors.affiliation: Center of Aesthetic Medicine, Department of Dermatology, Medical University Graz, Graz, Austria.
authors.forename: Daisy
authors.initials: D
authors.lastname: Kopera
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D064751:Ammonium Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001415:Back; D003020:Clothing; D005260:Female; D005349:Fibroins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010865:Pilot Projects; D012596:Scleroproteins / Q000627:therapeutic use*
chemical_list: D064751:Ammonium Compounds; D000890:Anti-Infective Agents; D012596:Scleroproteins; D005349:Fibroins