title: Over 10 years MRI observation of a patient with neuronal intranuclear inclusion disease.
abstract: We present a sporadic neuronal intranuclear inclusion disease (NIID) patient with neuropathy followed by cognitive dysfunction along with brain MRIs findings of leucoencephalopathy. Her cognitive impairment gradually progressed along with abnormal intensity lesions in diffusion-weighted images. This pathological and clinical deterioration resemble pathological process in prion diseases.
authors.affiliation: Division of Neurology, Department of Community Health Medicine, Hyogo College of Medicine Graduate School of Medicine, Nishinomiya, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Abe
authors.affiliation: Fujita Shinkeinaika Clinic, Higashiosaka, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Fujita
mesh_terms: D060825:Cognitive Dysfunction / Q000209:etiology*; D038524:Diffusion Magnetic Resonance Imaging; D018450:Disease Progression; D005260:Female; D006801:Humans; D045586:Intranuclear Inclusion Bodies; D056784:Leukoencephalopathies / Q000000981:diagnostic imaging* / Q000209:etiology; D008137:Longitudinal Studies; D008875:Middle Aged; D019636:Neurodegenerative Diseases / Q000150:complications / Q000000981:diagnostic imaging*