title: Strategies for Corrole Functionalization.
abstract: This review covers the functionalization reactions of meso-arylcorroles, both at the inner core, as well as the peripheral positions of the macrocycle. Experimental details for the synthesis of all known metallocorrole types and for the N-alkylation reactions are presented. Key peripheral functionalization reactions such as halogenation, formylation, carboxylation, nitration, sulfonation, and others are discussed in detail, particularly the nucleophilic aromatic substitution and the participation of corroles in cycloaddition reactions as 2π or 4π components (covering Diels-Alder and 1,3-dipolar cycloadditions). Other functionalizations of corroles include a large diversity of reactions, namely Wittig reactions, reactions with methylene active compounds, formation of amines, amides, and imines, and metal catalyzed reactions. At the final section, the reactions involving oxidation and ring expansion of the corrole macrocycle are described comprehensively.
authors.affiliation: Department of Chemistry and QOPNA, and ‡Department of Chemistry and CICECO, University of Aveiro , 3810-193 Aveiro, Portugal.
authors.forename: Joana F B
authors.initials: JF
authors.lastname: Barata
authors.affiliation: Department of Chemistry and QOPNA, and ‡Department of Chemistry and CICECO, University of Aveiro , 3810-193 Aveiro, Portugal.
authors.forename: M Graça P M S
authors.initials: MG
authors.lastname: Neves
authors.affiliation: Department of Chemistry and QOPNA, and ‡Department of Chemistry and CICECO, University of Aveiro , 3810-193 Aveiro, Portugal.
authors.forename: M Amparo F
authors.identifier: http://orcid.org/0000-0003-4423-3802
authors.initials: MA
authors.lastname: Faustino
authors.affiliation: Department of Chemistry and QOPNA, and ‡Department of Chemistry and CICECO, University of Aveiro , 3810-193 Aveiro, Portugal.
authors.forename: Augusto C
authors.initials: AC
authors.lastname: Tomé
authors.affiliation: Department of Chemistry and QOPNA, and ‡Department of Chemistry and CICECO, University of Aveiro , 3810-193 Aveiro, Portugal.
authors.forename: José A S
authors.identifier: http://orcid.org/0000-0001-5495-5126
authors.initials: JA
authors.lastname: Cavaleiro