title: [Factors influencing antiretroviral therapy adherence among HIV-infected people on antiretroviral therapy in Ili Kazakh Autonomous Prefecture].
abstract: Objective:To analyze factors influencing antiretroviral therapy (ART) adherence among human immunodeficiency virus (HIV) patients receiving ART at the town level in Ili Kazakh Autonomous Prefecture (Ili) in May 2015 and to document enhanced ART for acquired immunodeficiency syndrome (AIDS) cases.Methods:A cross-sectional survey was conducted using one-on-one interviews and data collection from the system of AIDS follow-up management in three ART services centers at the town level of Ili. The subjects were HIV-infected individuals, aged 18 years or older, who were receiving ART during the survey. The surveys collected demographic characteristics, information related to ART and status of engaging ART, smoking and drinking behavior, depression, and quality of life.Results:A total of 412 participants completed the survey. The age was (41.1±8.0) years (range, 19-67 years). Approximately 60.9% (251) were male and 39.1% (161) were female. The survey showed that 75.0% (309) of participants were in good adherence and theP(50) (P(25),P(75)) of quality of life was 56.31 (50.55, 59.42). Females demonstrated better adherence to ART (82.6% (n=133)) than males (70.1% (n=76)) (χ(2)=8.16,P=0.005). The compliance rate of participants (78.0% (n=54)) with depression was higher than non-depressed participants (63.5% (n=255)) (χ(2)=7.52,P=0.008). Multivariate logistic regression analyses showed that the probability of good adherence to ART increased with increasing quality of life (OR=1.06, 95%CI:1.02-1.09). Moreover, participants who consumed alcohol or disclosed their HIV infection status to families were less likely to have good adherence to ART (OR=0.26, 95%CI:0.13-0.53 andOR=0.31, 95%CI:0.13-0.72, respectively). Additionally, employed participants were also less likely to have good adherence to ART compared with unemployed participants (OR=0.45, 95%CI:0.21-0.97).Conclusion:HIV/AIDS patients primarily showed good adherence to ART. Factors related to ART adherence included alcohol consumption, informing family of infection, work status, and quality of life.
authors.affiliation: Department of Epidemiology and Healthy Statistics, School of Public Health, Anhui Medical University, Hefei 230032, China.
authors.forename: W
authors.initials: W
authors.lastname: Wang
authors.forename: W
authors.initials: W
authors.lastname: Liu
authors.forename: T
authors.initials: T
authors.lastname: Chen
authors.forename: N P
authors.initials: NP
authors.lastname: Liu
authors.forename: Y J
authors.initials: YJ
authors.lastname: Zheng
authors.forename: S D
authors.initials: SD
authors.lastname: Ye
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: X M
authors.initials: XM
authors.lastname: Wang
authors.forename: G Z
authors.initials: GZ
authors.lastname: Wang
authors.forename: H B
authors.initials: HB
authors.lastname: Zhang
mesh_terms: D000163:Acquired Immunodeficiency Syndrome; D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D023241:Antiretroviral Therapy, Highly Active; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D010349:Patient Compliance; D011788:Quality of Life; D011795:Surveys and Questionnaires
keywords: Acquired immunodeficiency syndrome; Antiretroviral therapy/ART; HIV; Medication adherence