title: Cochrane Corner: Extracts from The Cochrane Library.
abstract: The Cochrane Corner is a section in the journal that highlights systematic reviews relevant to otolaryngology-head and neck surgery, with invited commentary to aid clinical decision making. This installment features a pair of related Cochrane Reviews on intranasal steroids for chronic rhinosinusitis, which identify low- to moderate-quality evidence for a beneficial effect on overall symptoms, nasal congestion, and rhinorrhea. There is no evidence, however, to suggest superiority of any particular steroid preparation or drug delivery system. The related expert commentary should help clinicians make the best treatment decisions based on the studies and outcomes identified in these Cochrane Reviews.
authors.affiliation: 1 University of Utah, Salt Lake City, Utah, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Orlandi
authors.affiliation: 2 King's Health Partners Clinical Academic Groups, King's College, London, UK.
authors.forename: Clair
authors.initials: C
authors.lastname: Hopkins
authors.affiliation: 3 Norwich Medical School and James Paget University Hospital, Norwich, UK.
authors.forename: Carl
authors.initials: C
authors.lastname: Philpott
authors.affiliation: 4 Department of Otolaryngology, State University of New York Downstate Medical Center, Brooklyn, New York, USA.
authors.forename: Richard M
authors.initials: RM
authors.lastname: Rosenfeld
mesh_terms: D006801:Humans; D000281:Administration, Intranasal; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D002908:Chronic Disease; D012196:Review Literature as Topic; D012220:Rhinitis / Q000150:complications / Q000188:drug therapy; D012852:Sinusitis / Q000150:complications / Q000188:drug therapy
chemical_list: D000305:Adrenal Cortex Hormones
keywords: Cochrane Collaboration; chronic rhinosinusitis; evidence-based medicine; intranasal corticosteroids; systematic review