title: The Role of Impedance Planimetry in the Evaluation of Esophageal Disorders.
abstract: OBJECTIVE
  Impedance planimetry measures tissue wall distensibility as a function of pressure and cross-sectional area. Recent interest in this technique's relevance to the gastrointestinal tract has been accelerated by the availability of the functional lumen imaging probe, a catheter-based system that dynamically quantitates these biomechanical properties. Herein, we review the device's particular utility in the setting of esophageal pathology, including processes affecting the esophageal body as well as the upper and lower esophageal sphincters.
  
  
  RESULTS
  An expanding suite of disease-specific indications for impedance planimetry includes achalasia, gastroesophageal reflux disease, and eosinophilic esophagitis. The technique has also demonstrated a role in the intraoperative guidance of therapy and in the definition of hitherto unrecognized patterns of esophageal dysmotility. Device-specific technology remains in active evolution, which, in conjunction with progressively larger datasets, sets the stage for broader clinical applicability in the near future.
authors.affiliation: Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
authors.forename: Nitin K
authors.initials: NK
authors.lastname: Ahuja
authors.affiliation: Division of Gastroenterology and Hepatology, Stanford University School of Medicine, 300 Pasteur Drive, Room H0206B, MC: 5244, Stanford, CA, 94305, USA. john.clarke@stanford.edu.
authors.forename: John O
authors.initials: JO
authors.lastname: Clarke
mesh_terms: D017097:Electric Impedance; D057765:Eosinophilic Esophagitis / Q000175:diagnosis / Q000503:physiopathology; D004931:Esophageal Achalasia / Q000175:diagnosis / Q000503:physiopathology; D004935:Esophageal Diseases / Q000175:diagnosis* / Q000503:physiopathology; D015154:Esophageal Motility Disorders / Q000175:diagnosis / Q000503:physiopathology; D004943:Esophagogastric Junction / Q000503:physiopathology; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008365:Manometry / Q000379:methods
keywords: Dysphagia; EndoFLIP; EsoFLIP; Esophagogastric junction; FLIP; Fundoplication