title: Primary squamous cell carcinoma of the thyroid. Initial assessment and follow-up using18F-FDG PET/CT.
abstract: Squamous cell carcinoma of thyroid is an uncommon, very aggressive neoplasm, having a poor prognosis and poor response to chemotherapy and radiotherapy. Surgery is the initial treatment of choice, although it often presents as a widespread disease at the time of diagnosis, usually with cervical swelling that causes most of the symptoms due to local infiltration or metastasis. Local infiltration from adjacent tumour and metastatic disease needs to be excluded from other primary epidermoid carcinomas, in order to make a correct diagnosis. This also requires the typical cytokeratin pattern seen in histological studies. The case is presented of a 53 year-old man with a medical history of hepatocarcinoma, with a cervical hypermetabolic lesion detected in an18F-FDG PET/CT performed to exclude widespread disease. The follow-up of this lesion with this technique and its usefulness is also described.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Virgen del Rocío, Sevilla, España. Electronic address: luiscaballerogullon.mnuclear@gmail.com.
authors.forename: L
authors.initials: L
authors.lastname: Caballero Gullón
authors.affiliation: Servicio de Radiología, Hospital La Merced, Osuna (Sevilla), España.
authors.forename: E
authors.initials: E
authors.lastname: Carmona González
authors.affiliation: Servicio de Medicina Nuclear, Hospital Virgen del Rocío, Sevilla, España.
authors.forename: A
authors.initials: A
authors.lastname: Martínez Estévez
authors.affiliation: Servicio de Medicina Nuclear, Hospital Virgen del Rocío, Sevilla, España.
authors.forename: M P
authors.initials: MP
authors.lastname: Gómez Camarero
authors.affiliation: Servicio de Oncología, Hospital Virgen del Rocío, Sevilla, España.
authors.forename: J J
authors.initials: JJ
authors.lastname: Corral
authors.affiliation: Servicio de Medicina Nuclear, Hospital Virgen del Rocío, Sevilla, España.
authors.forename: I
authors.initials: I
authors.lastname: Borrego Dorado
mesh_terms: D001859:Bone Neoplasms / Q000556:secondary; D006528:Carcinoma, Hepatocellular; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000556:secondary; D017809:Fatal Outcome; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging*; D010166:Palliative Care; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: (18)F-FDG PET/CT; (18)F-FDG PET/TC; Carcinoma de células escamosas; Positron emission tomography; Squamous cell carcinoma; Thyroid; Tiroides; Tomografía por emisión de positrones