title: [Complex treatment of chronic cystitis in women].
abstract: OBJECTIVE
  Evaluation of the efficacy and safety of Phytolysin in complex treatment of female patients with chronic cystitis.
  
  
  METHODS
  40 women with chronic cystitis were examined from January 2016 to March 2016. Depending on the treatment, all patients were divided into two groups of 20 people. Main group of patients was treated with Fosfomycin (Monural) and Phytolysin. Control group of patients received monotherapy with fosfomycin.
  
  
  RESULTS
  The results were assessed at 1 and 2 months after initiation of therapy. Rapid normalization of the status and laboratory parameters, improvement of dynamics of the endoscopic view was observed in main group of patients.
  
  
  CONCLUSIONS
  The complex of biologically active substances contained in Phytolysin has antimicrobial, anti-inflammatory, antispasmodic, and immunomodulatory effects, promotes the normalization of urodynamics of lower urinary tract, reduces the risk of relapse of chronic recurrent cystitis. Thus, Phytolysin can be recommended as a component of complex therapy of exacerbations of chronic cystitis, as well as a drug for prevention of the disease in disease-free periods.
authors.affiliation: SBEI HPE Altai State Medical University of RMH.
authors.forename: A I
authors.initials: AI
authors.lastname: Neymark
authors.affiliation: NGHCI RCH at the station Barnaul JSC Russian Railways.
authors.forename: M V
authors.initials: MV
authors.lastname: Razdorskaya
authors.affiliation: SBEI HPE Altai State Medical University of RMH.
authors.forename: B A
authors.initials: BA
authors.lastname: Neymark
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016022:Case-Control Studies; D002908:Chronic Disease; D003556:Cystitis / Q000188:drug therapy* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D005260:Female; D005578:Fosfomycin / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D005578:Fosfomycin
keywords: Phytolysin; chronic cystitis; fosfomycin