title: Acute kidney injury in pancreatic surgery; association with urine output and intraoperative fluid administration.
abstract: BACKGROUND
  Acute kidney injury (AKI) is a devastating postoperative complication. Intraoperative urine output is assumed to reflect patient's intravascular volume and kidney function. We thus evaluated the incidence of postoperative AKI and its association with intraoperative urine output and the volume of fluid administered.
  
  
  METHODS
  A retrospective study on 153 consecutive patients admitted to Tel Aviv Medical Center for pancreatic surgery.
  
  
  RESULTS
  The incidence of AKI in patients undergoing pancreatic surgery was 9.8%. Oliguria was not a predictor of AKI. There was no association between the amount of fluids administered and AKI. Pulmonary disease is an independent predictor of AKI. AKI is an independent predictor of mortality.
  
  
  CONCLUSIONS
  AKI is common in patients undergoing pancreas surgeries and is associated with high mortality. Neither urine output, nor the volume of fluids administered correlate with postoperative AKI. Low diuresis is therefore not a sole marker for fluid administration.
authors.affiliation: Division of Anesthesiology, Pain, and Intensive Care, Tel Aviv Medical Center, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel; Departments of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
authors.forename: Or
authors.initials: O
authors.lastname: Goren
authors.affiliation: Departments of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
authors.forename: Amalia
authors.initials: A
authors.lastname: Levy
authors.affiliation: Division of Anesthesiology, Pain, and Intensive Care, Tel Aviv Medical Center, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel.
authors.forename: Anat
authors.initials: A
authors.lastname: Cattan
authors.affiliation: Department of Surgery, Tel Aviv Medical Center, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel.
authors.forename: Guy
authors.initials: G
authors.lastname: Lahat
authors.affiliation: Division of Anesthesiology, Pain, and Intensive Care, Tel Aviv Medical Center, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel. Electronic address: iditm@tlvmc.gov.il.
authors.forename: Idit
authors.initials: I
authors.lastname: Matot
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology*; D000368:Aged; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D007557:Israel / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D014556:Urine
keywords: Acute kidney injury; Pancreatic surgery; Perioperative management; Urine output