title: A novel method for heterocyclic amide-thioamide transformations.
abstract: In this paper, we introduce a novel and convenient method for the transformation of heterocyclic amides into heteocyclic thioamides. A two-step approach was applied for this transformation: Firstly, we applied a chlorination of the heterocyclic amides to afford the corresponding chloroheterocycles. Secondly, the chloroherocycles andN-cyclohexyl dithiocarbamate cyclohexylammonium salt were heated in chloroform for 12 h at 61 °C to afford heteocyclic thioamides in excellent yields.
authors.affiliation: Physics and Math. Engineering Dept., Faculty of Engineering, Port-Said University, Port Said, Egypt.
authors.forename: Walid
authors.initials: W
authors.lastname: Fathalla
authors.affiliation: Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia, Egypt.
authors.forename: Ibrahim A I
authors.initials: IA
authors.lastname: Ali
authors.affiliation: Centre for Syntheses at Sustainable Conditions and Their Management, Faculty of Science, Masaryk University, Brno, Czech Republic.
authors.forename: Pavel
authors.initials: P
authors.lastname: Pazdera
keywords: N-cyclohexyl dithiocarbamate cyclohexylammonium salt; heterocyclic amides; heterocyclic thioamides; novel thiating agent; thiation