title: Coupling Effect of Double Lungs on a VCV Ventilator with Automatic Secretion Clearance Function.
abstract: For patients with mechanical ventilation, secretions in airway are harmful and sometimes even mortal, it's of great significance to clear secretion timely and efficiently. In this paper, a new secretion clearance method for VCV (volume-controlled ventilation) ventilator is put forward, and a secretion clearance system with a VCV ventilator and double lungs is designed. Furthermore, the mathematical model of the secretion clearance system is built and verified via experimental study. Finally, to illustrate the influence of key parameters of respiratory system and secretion clearance system on the secretion clearance characteristics, coupling effects of two lungs on VCV secretion clearance system are studied by an orthogonal experiment, it can be obtained that rise of tidal volume adds to efficiency of secretion clearance while effect of area, compliance, and suction pressure on efficiency of secretion clearance needs further study. Rise of compliance improves bottom pressure of secretion clearance while rise of area, tidal volume, and suction pressure decreases bottom pressure of secretion clearance. This paper can be referred to in researches of secretion clearance for VCV.
authors.forename: Yan
authors.initials: Y
authors.lastname: Shi
authors.forename: Bolun
authors.initials: B
authors.lastname: Zhang
authors.forename: Maolin
authors.initials: M
authors.lastname: Cai
authors.forename: Weiqing
authors.initials: W
authors.lastname: Xu
mesh_terms: D000465:Algorithms; D012634:Bodily Secretions / Q000378:metabolism*; D004867:Equipment Design; D006801:Humans; D008168:Lung / Q000503:physiopathology; D008490:Medical Informatics; D008962:Models, Theoretical; D011312:Pressure; D012121:Respiration, Artificial / Q000295:instrumentation*; D015656:Respiratory Mechanics; D012984:Software; D013396:Suction; D013990:Tidal Volume; D012122:Ventilators, Mechanical