title: [Feasibility of using connective tissue prosthesis for autoplastic repair of urinary bladder wall defects (an experimental study)].
abstract: Experiments on laboratory rats have shown the feasibility of autoplastic repair of urinary bladder wall defects using a connective-tissue capsule formed as the result of an inflammatory response to the presence of a foreign body. The formation of connective tissue prosthesis is characterized by developing fibrous connective tissue, ordering of collagen fibers, reducing the number of cells per unit area with a predominance of more mature cells - fibroblasts. With increasing time of observation, connective tissue prostheses were found to acquire a morphological structure similar to that of the urinary bladder wall. By month 12, the mucosa, the longitudinal and circular muscle layers were formed. The proposed method of partial autoplastic repair of urinary bladder wall is promising, has good long-term results, but requires further experimental studies.
authors.affiliation: Institute of Immunology and Physiology, Ural Branch of RAS, Ekaterinburg.|Institute of Medical Cell Technologies, Ekaterinburg.
authors.forename: N V
authors.initials: NV
authors.lastname: Tyumentseva
authors.affiliation: Institute of Immunology and Physiology, Ural Branch of RAS, Ekaterinburg.|Ural Federal University n. a. the first President of Russia B.N.Yeltsin, Yekaterinburg.|Institute of Medical Cell Technologies, Ekaterinburg.
authors.forename: B G
authors.initials: BG
authors.lastname: Yushkov
authors.affiliation: Institute of Immunology and Physiology, Ural Branch of RAS, Ekaterinburg.|Ural Federal University n. a. the first President of Russia B.N.Yeltsin, Yekaterinburg.|Institute of Medical Cell Technologies, Ekaterinburg.
authors.forename: S Y
authors.initials: SY
authors.lastname: Medvedeva
authors.affiliation: Sverdlovsk Regional Hospital 1, Ekaterinburg.
authors.forename: R Y
authors.initials: RY
authors.lastname: Kovalenko
authors.affiliation: Sverdlovsk Regional Hospital 1, Ekaterinburg.
authors.forename: O K
authors.initials: OK
authors.lastname: Uzbekov
authors.affiliation: Ural State Medical University, Ekaterinburg.
authors.forename: V N
authors.initials: VN
authors.lastname: Zhuravlev
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D003238:Connective Tissue / Q000637:transplantation*; D019919:Prosthesis Implantation; D051381:Rats; D019651:Plastic Surgery Procedures; D001743:Urinary Bladder / Q000601:surgery*; D013520:Urologic Surgical Procedures
keywords: autotransplantation; bladder; connective tissue prosthesis