title: Lanthanum Deposition in the Stomach: Usefulness of Scanning Electron Microscopy for Its Detection.
abstract: After having been treated with lanthanum carbonate administration for 4 years for hyperphosphatemia, a 75-year-old Japanese woman undergoing hemodialysis was diagnosed with lanthanum phosphate deposition in the stomach. The deposition, seen as white microgranules, was observed using esophagogastroduodenoscopy with magnifying observation. To the best of our knowledge, these are the minutest endoscopy images of lanthanum phosphate deposition in the gastric mucosa. Scanning electron microscopy (SEM) observation enabled easier identification of the deposited material, which was visible as bright areas. The present case suggests the usefulness of SEM observation in the detection of lanthanum phosphate deposition in the gastrointestinal tract.
authors.affiliation: Departments of Gastroenterology and Hepatology, General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.iwamuromasaya@yahoo.co.jp.
authors.forename: Masaya
authors.initials: M
authors.lastname: Iwamuro
authors.forename: Haruo
authors.initials: H
authors.lastname: Urata
authors.forename: Takehiro
authors.initials: T
authors.lastname: Tanaka
authors.forename: Akemi
authors.initials: A
authors.lastname: Ando
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nada
authors.forename: Kosuke
authors.initials: K
authors.lastname: Kimura
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamauchi
authors.forename: Chiaki
authors.initials: C
authors.lastname: Kusumoto
authors.forename: Fumio
authors.initials: F
authors.lastname: Otsuka
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Okada
mesh_terms: D000368:Aged; D016145:Endoscopy, Digestive System; D005260:Female; D005753:Gastric Mucosa / Q000000981:diagnostic imaging*; D006801:Humans; D054559:Hyperphosphatemia / Q000188:drug therapy; D007676:Kidney Failure, Chronic / Q000628:therapy; D007811:Lanthanum / Q000032:analysis* / Q000737:chemistry; D008855:Microscopy, Electron, Scanning / Q000379:methods*
chemical_list: C119467:lanthanum carbonate; D007811:Lanthanum
keywords: hyperphosphatemia; lanthanum carbonate; scanning electron microscopy analysis; xanthoma