title: Pros-IT CNR: an Italian prostate cancer monitoring project.
abstract: OBJECTIVE
  The Pros-IT CNR project aims to monitor a sample of Italian males ≥18 years of age who have been diagnosed in the participating centers with incident prostate cancer, by analyzing their clinical features, treatment protocols and outcome results in relation to quality of life.
  
  
  METHODS
  Pros-IT CNR is an observational, prospective, multicenter study. The National Research Council (CNR), Neuroscience Institute, Aging Branch (Padua) is the promoting center. Ninety-seven Italian centers located throughout Italy were involved. The field study began in September 1, 2014. Subjects eligible were diagnosed with biopsy-verified prostate cancer, naïve. A sample size of 1500 patients was contemplated. A baseline assessment including anamnestic data, clinical history, risk factors, the initial diagnosis, cancer staging information and quality of life (Italian UCLA Prostate Cancer Index; SF-12 Scale) was completed. Six months after the initial diagnosis, a second assessment evaluating the patient's health status, the treatment carried out, and the quality of life will be made. A third assessment, evaluating the treatment follow-up and the quality of life, will be made 12 months after the initial diagnosis. The 4th, 5th, 6th and 7th assessments, similar to the third, will be completed 24, 36, 48 and 60 months after the initial diagnosis, respectively, and will include also a Food Frequency Questionnaire and the Physical Activity Scale for the Elderly.
  
  
  CONCLUSIONS
  The study will provide information on patients' quality of life and its variations over time in relation to the treatments received for the prostate cancer.
authors.affiliation: CNR, Aging Branch, Neuroscience Institute, Via Giustiniani 2, 35128, Padova, Italy. marianna.noale@in.cnr.it.
authors.forename: Marianna
authors.identifier: http://orcid.org/0000-0001-7115-139X
authors.initials: M
authors.lastname: Noale
authors.affiliation: CNR, Aging Branch, Neuroscience Institute, Via Giustiniani 2, 35128, Padova, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Maggi
authors.affiliation: Azienda Ospedaliera Universitaria integrata di Verona, Verona, Italy.
authors.forename: Walter
authors.initials: W
authors.lastname: Artibani
authors.affiliation: Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore di Milano-sede di Roma, Milan, Italy.
authors.forename: Pier Francesco
authors.initials: PF
authors.lastname: Bassi
authors.affiliation: Prostate Group of AIRO-Italian Association for Radiation Oncology, Brescia, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Bertoni
authors.affiliation: Ospedale San Donato, Arezzo, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Bracarda
authors.affiliation: Ospedale Sant'Anna, Como, Italy.
authors.forename: Giario Natale
authors.initials: GN
authors.lastname: Conti
authors.affiliation: IRCCS San Martino-IST, Genova, Italy.
authors.forename: Renzo
authors.initials: R
authors.lastname: Corvò
authors.affiliation: Università di Firenze, Florence, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Gacci
authors.affiliation: Ospedale S. Giuseppe, Milano, Italy.
authors.forename: Pierpaolo
authors.initials: P
authors.lastname: Graziotti
authors.affiliation: Università di Brescia, Brescia, Italy.
authors.forename: Stefano Maria
authors.initials: SM
authors.lastname: Magrini
authors.affiliation: Università di Roma Sapienza, Roma, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Maurizi Enrici
authors.affiliation: Università degli Studi di Napoli Federico II, Napoli, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Mirone
authors.affiliation: Università Politecnica delle Marche, Ancona, Italy.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Montironi
authors.affiliation: Università Campus Bio-medico, Roma, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Muto
authors.affiliation: Malzoni Center, Avellino, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Pecoraro
authors.affiliation: Policlinico di Abano Terme, Padova, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Porreca
authors.affiliation: Università di Torino, Turin, Italy.
authors.forename: Umberto
authors.initials: U
authors.lastname: Ricardi
authors.affiliation: Ospedale Sant'Andrea, Roma, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Tubaro
authors.affiliation: Istituto Oncologico Veneto IOV-IRCCS, Padova, Italy.
authors.forename: Vittorina
authors.initials: V
authors.lastname: Zagonel
authors.affiliation: Università di Padova, Padova, Italy.
authors.forename: Filiberto
authors.initials: F
authors.lastname: Zattoni
authors.affiliation: CNR, Aging Branch, Neuroscience Institute, Via Giustiniani 2, 35128, Padova, Italy.
authors.forename: Gaetano
authors.initials: G
authors.lastname: Crepaldi
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods / Q000706:statistics & numerical data; D019468:Disease Management; D006304:Health Status; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000523:psychology / Q000628:therapy; D011788:Quality of Life
keywords: Italian UCLA Cancer Index; Prostate cancer; Prostate cancer treatments; Quality of life; SF-12 Scale