title: Mobile phone use and risk for intracranial tumors and salivary gland tumors - A meta-analysis.
abstract: Results of epidemiological studies on the association between use of mobile phone and brain cancer are ambiguous, as well as the results of 5 meta-analysis studies published to date. Since the last meta-analysis (2009), new case-control studies have been published, which theoretically could affect the conclusions on this relationship. Therefore, we decided to perform a new meta-analysis. We conducted a systematic review of multiple electronic data bases for relevant publications. The inclusion criteria were: original papers, case-control studies, published till the end of March 2014, measures of association (point estimates as odds ratio and confidence interval of the effect measured), data on individual exposure. Twenty four studies (26 846 cases, 50 013 controls) were included into the meta-analysis. A significantly higher risk of an intracranial tumor (all types) was noted for the period of mobile phone use over 10 years (odds ratio (OR) = 1.324, 95% confidence interval (CI): 1.028-1.704), and for the ipsilateral location (OR = 1.249, 95% CI: 1.022-1.526). The results support the hypothesis that long-term use of mobile phone increases risk of intracranial tumors, especially in the case of ipsilateral exposure. Further studies are needed to confirm this relationship. Int J Occup Med Environ Health 2017;30(1)27-43.
authors.affiliation: Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Work Physiology and Ergonomics). alab@imp.lodz.pl.
authors.forename: Alicja
authors.initials: A
authors.lastname: Bortkiewicz
authors.affiliation: Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Work Physiology and Ergonomics). elag@imp.lodz.pl.
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Gadzicka
authors.affiliation: University of Lodz, Łódź, Poland (Faculty of Educational Sciences, Institute of Psychology, Chair of Psychological Research Methodology and Statistics). wiesiek_szym@yahoo.co.uk.
authors.forename: Wiesław
authors.initials: W
authors.lastname: Szymczak
mesh_terms: D001932:Brain Neoplasms / Q000453:epidemiology* / Q000209:etiology; D016022:Case-Control Studies; D040421:Cell Phone; D004574:Electromagnetic Fields / Q000009:adverse effects; D004781:Environmental Exposure; D006801:Humans; D012468:Salivary Gland Neoplasms / Q000453:epidemiology* / Q000209:etiology
keywords: acoustic neuroma; brain tumors; case-control studies; cellular phone; electromagnetic fields; salivary gland tumors