title: Autologous incus versus titanium partial ossicular replacement prosthesis in reconstruction of Austin type A ossicular defects: a prospective randomised clinical trial.
abstract: OBJECTIVE
  This study aimed to compare the functional and anatomical outcomes of ossiculoplasty using an autograft incus or a titanium partial ossicular replacement prosthesis for reconstructing Austin type A ossicular defects.
  
  
  METHODS
  Patients with Austin A ossicular defects were randomly divided into two groups: one group underwent ossiculoplasty with an autologous incus (the autologous incus group) and the other underwent ossiculoplasty with a titanium partial ossicular replacement prosthesis (the titanium prosthesis group). Otoscopic examination and audiological assessment was done pre-operatively and at 3, 6 and 12 months post-operatively.
  
  
  RESULTS
  A post-operative average air-bone gap closure of less than 20 dB was seen in 13 patients (65 per cent) in the autologous incus group and 7 (35 per cent) in the titanium prosthesis group. There were fewer post-operative complications in the autologous incus group (20 per cent) than in the titanium prosthesis group (45 per cent).
  
  
  CONCLUSIONS
  Hearing outcomes and graft take up after ossiculoplasty were significantly better when an autologous incus rather than a titanium partial ossicular replacement prosthesis was used to reconstruct Austin type A ossicular defects. The major disadvantages of the titanium prosthesis were unpredictable results and more post-operative complications.
authors.affiliation: Department of Otorhinolaryngology,Jawaharlal Nehru Medical College,Belagavi,India.
authors.forename: Naragund
authors.initials: N
authors.lastname: Amith
authors.affiliation: Department of Otorhinolaryngology,Jawaharlal Nehru Medical College,Belagavi,India.
authors.forename: Mudhol
authors.initials: M
authors.lastname: Rs
mesh_terms: D000293:Adolescent; D000328:Adult; D001299:Audiometry; D002648:Child; D004429:Ear Ossicles / Q000002:abnormalities* / Q000601:surgery*; D005260:Female; D006309:Hearing; D006314:Hearing Loss, Conductive / Q000151:congenital / Q000601:surgery; D006801:Humans; D007188:Incus / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D009998:Ossicular Prosthesis / Q000009:adverse effects; D019933:Ossicular Replacement / Q000379:methods*; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods; D014025:Titanium; D016896:Treatment Outcome; D014433:Tympanoplasty / Q000379:methods*; D055815:Young Adult
chemical_list: D014025:Titanium
keywords: Incus; Ossicular Replacement Prosthesis