title: [Results of a multicenter non-interventional study on the efficacy and safety of NeyroDoz complex for sexual dysfunction in men].
abstract: The article presents the results of a multi-center observational study carried out in 2014-2015 comprising 630 male patients from 23 Russian health care institutions. The study aimed to accumulate epidemiological data on sexual dysfunction in men and test the efficacy and safety of biologically active complex NeyroDoz. Data for the study were collected using questionnaires. The study findings showed a high prevalence of premature ejaculation (PE) in 38.2% of patients with chronic prostatitis (CP) and in 33.25% of patients with erectile dysfunction (ED). The data were analyzed for the total study population (n=630) and separately for three groups of patients selected according to the presence of PE (n=582), orgasmic disorders without PE (n=17) and increased anxiety related to urological diseases without PE (n=31). In all patients of the study, NeyroDoz intake produced a statistically significant increase in the intensity of orgasm from 5,0+/-2,2 to 7,6+/-1,8 points, duration of sexual intercourse from 3,3+/-5,4 to 6,5+/-4,8 min, and satisfaction with sexual intercourse from 1,4+/-0,7 to 3,1+/-1,1 points. In 81% of PE patients the duration of penetration phase of sexual intercourse increased by 50% of the baseline values. The intensity of orgasm increased on average by 60% and 75% in men with PE and orgasm disorders without PE, respectively. Reduction of psycho-emotional burden was observed in 90% of patients with anxiety and depression. The dietary supplement NeyroDoz showed clinical efficacy and safety in the combined treatment of sexual dysfunction in men.
authors.affiliation: Department of Urology and Andrology of SFM, Lomonosov Moscow State University.
authors.forename: A A
authors.initials: AA
authors.lastname: Kamalov
authors.affiliation: Department of Urology and Andrology of SFM, Lomonosov Moscow State University.|Research Institute of Public Health and Medical Management of the Moscow Health Department, D.V. Melik-Guseinov).
authors.forename: L A
authors.initials: LA
authors.lastname: Khodyreva
authors.affiliation: Department of Urology and Andrology of SFM, Lomonosov Moscow State University.|Research Institute of Public Health and Medical Management of the Moscow Health Department, D.V. Melik-Guseinov).
authors.forename: A A
authors.initials: AA
authors.lastname: Dudareva
authors.affiliation: Department of Urology and Andrology of SFM, Lomonosov Moscow State University.
authors.forename: V K
authors.initials: VK
authors.lastname: Karpov
authors.affiliation: Department of Urology and Andrology of SFM, Lomonosov Moscow State University.
authors.forename: D A
authors.initials: DA
authors.lastname: Okhobotov
authors.affiliation: JSC Nizhpharm JSC STADA Marketing, Moscow.
authors.forename: M A
authors.initials: MA
authors.lastname: Starosel'skaya
authors.affiliation: Department of Surgery with the Course of Urology, E.A. Wagner Perm State Medical University, Perm.
authors.forename: M I
authors.initials: MI
authors.lastname: Davidov
authors.affiliation: Department of Urology, Regional Clinical Hospital 1, Orenburg.
authors.forename: M D
authors.initials: MD
authors.lastname: Kuz'min
mesh_terms: D000328:Adult; D000368:Aged; D019587:Dietary Supplements; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D061686:Premature Ejaculation / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D011469:Prostatic Diseases / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology
keywords: anxiety and depression; dietary supplement NeyroDoz; premature ejaculation; serotonin; sexual dysfunction in males