title: Outcomes after cataract surgery in eyes with pseudoexfoliation: Results from the Veterans Affairs Ophthalmic Surgery Outcomes Data Project.
abstract: OBJECTIVE
  To compare clinical outcomes of cataract surgery in eyes with and without pseudoexfoliation (PXF).
  
  
  METHODS
  Retrospective deidentified data analysis.
  
  
  METHODS
  A total of 123 PXF and 4776 non-PXF eyes of patients who underwent cataract surgery.
  
  
  METHODS
  We compared data on visual acuity, Visual Function Questionnaire (VFQ)-based quality of life, and complications in PXF and non-PXF eyes from the Veterans Affairs (VA) Ophthalmic Surgery Outcomes Data Project across 5 VA medical centres.
  
  
  RESULTS
  Pupillary expansion devices were used in 31 (25.2%) PXF cases and 398 (8.4%) non-PXF cases (p < 0.0001). Capsular tension rings were used in 6 (4.9%) PXF cases and 55 (1.2%) non-PXF cases (p < 0.004). The following complications occurred more frequently in PXF cases: zonular dehiscence without vitrectomy (4 [3.3%] PXF cases vs 40 [0.8%] non-PXF cases p = 0.02), persistent inflammation (28 [24.1%] vs 668 [14.5%]; p = 0.007), and persistent intraocular pressure elevation (5 [4.3%] vs 68 [1.5%]; p = 0.03). Best corrected visual acuity (BCVA) improved in both groups after 1 month, but 87 (83.7%) PXF cases achieved postoperative BCVA better than or equal to 20/40 compared to 3991 (93.8%) non-PXF cases (p = 0.0003). There was no significant difference in the postoperative composite VFQ scores between PXF (82.1 ± 16.9) and non-PXF cases (84.2 ± 16.8, p = 0.09).
  
  
  CONCLUSIONS
  Several complications occurred more frequently in the PXF group compared to the non-PXF group, and fewer PXF cases achieved BCVA better than or equal to 20/40. Despite this, both groups experienced similar improvement in vision-related quality of life after cataract surgery.
authors.affiliation: Veterans Affairs Boston Healthcare System, Ophthalmology Department, Jamaica Plain, MA; Harvard Medical School, Department of Ophthalmology, Boston, MA.
authors.forename: Angela
authors.initials: A
authors.lastname: Turalba
authors.affiliation: Veterans Affairs Boston Healthcare System, Ophthalmology Department, Jamaica Plain, MA.
authors.forename: Tulay
authors.initials: T
authors.lastname: Cakiner-Egilmez
authors.affiliation: Veterans Affairs Boston Healthcare System, Ophthalmology Department, Jamaica Plain, MA; Harvard Medical School, Department of Ophthalmology, Boston, MA.
authors.forename: Abhishek R
authors.initials: AR
authors.lastname: Payal
authors.affiliation: Veterans Affairs Boston Healthcare System, Ophthalmology Department, Jamaica Plain, MA.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Gonzalez-Gonzalez
authors.affiliation: Veterans Affairs Tennessee Valley Healthcare System Center, Nashville, TN; Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Chomsky
authors.affiliation: St Louis Veterans Affairs Medical Center, Ophthalmology Department, Saint Louis, MO; Washington University School of Medicine, Department of Ophthalmology and Visual Sciences, St. Louis, MO.
authors.forename: David E
authors.initials: DE
authors.lastname: Vollman
authors.affiliation: Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX; Cullen Eye Institute, Baylor College of Medicine, Houston, TX.
authors.forename: Elizabeth F
authors.initials: EF
authors.lastname: Baze
authors.affiliation: Department of Defense, Veterans Affairs Vision Center of Excellence, Bethesda, MD.
authors.forename: Mary G
authors.initials: MG
authors.lastname: Lawrence
authors.affiliation: Veterans Affairs Boston Healthcare System, Ophthalmology Department, Jamaica Plain, MA; Harvard Medical School, Department of Ophthalmology, Boston, MA; Boston University School of Medicine, Department of Ophthalmology, Boston, MA.. Electronic address: mary.daly2@va.gov.
authors.forename: Mary K
authors.initials: MK
authors.lastname: Daly
mesh_terms: D000368:Aged; D002386:Cataract / Q000150:complications*; D017889:Exfoliation Syndrome / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology*; D011788:Quality of Life; D012189:Retrospective Studies; D014481:United States / Q000453:epidemiology; D014493:United States Department of Veterans Affairs / Q000706:statistics & numerical data*; D014792:Visual Acuity