title: Vibration-Induced Nystagmus: A Biomarker for Vestibular Deficits - A Synopsis.
abstract: A review of more than 20 years of experience with vibratory stimulation in vestibular diseases is given. Vibrations in a frequency frame of 30-60 Hz are applied on the mastoid during 20 s. Eye movements are recorded by video-oculography to detect a vibration-induced nystagmus (VIN). A VIN occurs in cases of a side difference between the peripheral vestibular receptors beating to the side of better excitability. In patients with central lesions, a VIN does not appear generally, only exceptionally if the lesion is located laterally in the brain stem. In healthy subjects, a VIN does not occur. The VIN can be considered as an additional tool to detect a peripheral side difference and can reduce the need for caloric stimulation.
authors.affiliation: HNO-Klinik Bogenhausen (Gaertner-Klinik), Munich, Germany.
authors.forename: Karl-Friedrich
authors.initials: KF
authors.lastname: Hamann
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009759:Nystagmus, Pathologic / Q000175:diagnosis* / Q000209:etiology; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D015837:Vestibular Diseases / Q000175:diagnosis* / Q000209:etiology; D014724:Vestibular Function Tests; D014732:Vibration / Q000009:adverse effects*
chemical_list: D015415:Biomarkers