title: [Geriatric inpatients with iron deficiency-associated Restless Legs Syndrome. A retrospective analysis].
abstract: The Restless Legs Syndrome (RLS) is a clinically relevant condition in geriatric patients. An association between iron deficiency and RLS is largely acknowledged. The clinical and therapeutic management of iron deficiency-associated RLS has been, however, poorly evaluated in geriatric patients.
  
  
  
  Data from all RLS inpatients admitted to a geriatric unit between 2009 and 2011 were retrospectively collected on demographics and clinical characteristics, iron status, drug treatment including iron substitution, as well as comprehensive geriatric assessment (CGA) scores.
  
  
  
  RLS was diagnosed in 56 of the 4,063 admitted patients during the two years. Of the RLS cases, 20 (36%) showed iron deficiency. Thirteen of these were treated with iron substitution according to the existing guidelines. Both RLS patients with and without iron deficiency showed a significant clinical improvement between admission to discharge according to the CGA scores.
  
  
  
  Iron substituted geriatric patients with iron deficiency-associated RLS substantially benefited from the treatment, similarly to RLS patients without iron deficiency. A multidimensional assessment, careful iron metabolism examination and adequate treatment choice should be equally importantly considered in geriatric patients with RLS.
authors.affiliation: Klinik für Geriatrie am St. Marien-Hospital, Köln, Deutschland.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Lieske
authors.affiliation: Klinik für Geriatrie am St. Marien-Hospital, Köln, Deutschland. gabriele.roehrig@uk-koeln.de.|Schwerpunkt Klinische Altersforschung, Klinik II für Innere Medizin der Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland. gabriele.roehrig@uk-koeln.de.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Röhrig
authors.affiliation: Institut für Medizinische Statistik, Informatik und Epidemiologie an der Medizinischen Fakultät der Universität zu Köln, Köln, Deutschland.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Becker
authors.affiliation: Klinik für Geriatrie am St. Marien-Hospital, Köln, Deutschland.
authors.forename: Ralf-Joachim
authors.initials: RJ
authors.lastname: Schulz
authors.affiliation: Schwerpunkt Klinische Altersforschung, Klinik II für Innere Medizin, Universitätsklinikum Köln, Köln, Deutschland.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Polidori
authors.affiliation: Klinik für Neurologie der Universität Ulm, Ulm, Deutschland.
authors.forename: Jan
authors.initials: J
authors.lastname: Kassubek
mesh_terms: D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007297:Inpatients; D007501:Iron / Q000627:therapeutic use; D012148:Restless Legs Syndrome / Q000188:drug therapy* / Q000209:etiology; D012189:Retrospective Studies
chemical_list: D007501:Iron
keywords: comprehensive geriatric assessment; diagnosis; geriatrics; iron deficiency; restless legs syndrome