title: IROA: International Register of Open Abdomen, preliminary results.
abstract: No definitive data about open abdomen (OA) epidemiology and outcomes exist. The World Society of Emergency Surgery (WSES) and the Panamerican Trauma Society (PTS) promoted the International Register of Open Abdomen (IROA).
  
  
  
  A prospective observational cohort study including patients with an OA treatment. Data were recorded on a web platform (Clinical Registers®) through a dedicated website: www.clinicalregisters.org.
  
  
  
  Four hundred two patients enrolled. Adult patients: 369 patients; Mean age: 57.39±18.37; 56% male; Mean BMI: 36±5.6. OA indication: Peritonitis (48.7%), Trauma (20.5%), Vascular Emergencies/Hemorrhage (9.4%), Ischemia (9.1%), Pancreatitis (4.2%),Post-operative abdominal-compartment-syndrome (3.9%), Others (4.2%). The most adopted Temporary-abdominal-closure systems were the commercial negative pressure ones (44.2%). During OA 38% of patients had complications; among them 10.5% had fistula. Definitive closure: 82.8%; Mortality during treatment: 17.2%. Mean duration of OA: 5.39(±4.83) days; Mean number of dressing changes: 0.88(±0.88). After-closure complications: (49.5%) and Mortality: (9%). No significant associations among TACT, indications, mortality, complications and fistula. A linear correlationexists between days of OA and complications (Pearson linear correlation = 0.326p<0.0001) and with the fistula development (Pearson = 0.146p= 0.016). Pediatric patients: 33 patients. Mean age: 5.91±(3.68) years; 60% male. Mortality: 3.4%; Complications: 44.8%; Fistula: 3.4%. Mean duration of OA: 3.22(±3.09) days.
  
  
  
  Temporary abdominal closure is reliable and safe. The different techniques account for different results according to the different indications. In peritonitis commercial negative pressure temporary closure seems to improve results. In trauma skin-closure and Bogotà-bag seem to improve results.
  
  
  
  ClinicalTrials.gov NCT02382770.
authors.affiliation: General, Emergency and Trauma Surgery Department, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127 Bergamo, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Coccolini
authors.affiliation: General, Emergency and Trauma Surgery Department, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127 Bergamo, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Montori
authors.affiliation: General, Emergency and Trauma Surgery Department, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127 Bergamo, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Ceresoli
authors.affiliation: Emergency Surgery Department, Parma University Hospital, Parma, Italy.
authors.forename: Fausto
authors.initials: F
authors.lastname: Catena
authors.affiliation: Virginia Commonwealth University, Richmond, VA USA.
authors.forename: Rao
authors.initials: R
authors.lastname: Ivatury
authors.affiliation: General Surgery, Letterkenny Hospital, Donegal, Ireland.
authors.forename: Michael
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authors.lastname: Sugrue
authors.affiliation: General and Emergency Surgery Department, Macerata Hospital, Macerata, Italy.
authors.forename: Massimo
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authors.lastname: Sartelli
authors.affiliation: General, Emergency and Trauma Surgery Department, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127 Bergamo, Italy.
authors.forename: Paola
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authors.affiliation: Neuro Intensive Care Unit Department, Papa Giovanni XXIII Hospital, Bergamo, Italy.
authors.forename: Davide
authors.initials: D
authors.lastname: Corbella
authors.affiliation: General, Emergency and Trauma Surgery Department, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127 Bergamo, Italy.
authors.forename: Francesco
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authors.lastname: Salvetti
authors.affiliation: Emergency Surgery Hospital, Bucharest, Romania.
authors.forename: Ionut
authors.initials: I
authors.lastname: Negoi
authors.affiliation: Emergency Surgery Department, Ferrara University Hospital, Ferrara, Italy.
authors.forename: Monica
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authors.lastname: Zese
authors.affiliation: Emergency Surgery Department, Ferrara University Hospital, Ferrara, Italy.
authors.forename: Savino
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authors.affiliation: Emergency Surgery Department, Ferrara University Hospital, Ferrara, Italy.
authors.forename: Stefano
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authors.forename: Sergei
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authors.affiliation: Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
authors.forename: Christian
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authors.affiliation: Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
authors.forename: Massimo
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authors.affiliation: Kipshidze Central University Hospital, Kipshidze, Georgia.
authors.forename: Zaza
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authors.lastname: Demetrashvili
authors.affiliation: HPB Surgery, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy.
authors.forename: Daniele
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authors.lastname: Dondossola
authors.affiliation: University Hospital "Prof Stoian Kirkovich" AD, Stara Zagora, Bulgaria.
authors.forename: Yovcho
authors.initials: Y
authors.lastname: Yovtchev
authors.affiliation: Fourth Surgical Department, Hospital George Papanikolau, Aristotle University, Thessaloniki, Greece.
authors.forename: Orestis
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authors.lastname: Ioannidis
authors.affiliation: General Surgery, Infermi Hospital, Rimini, Italy.
authors.forename: Giuseppe
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authors.affiliation: Pediatric Intensive Care Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy.
authors.forename: Mirco
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authors.lastname: Nacoti
authors.affiliation: LAS + USC Medical Centre, Los Angeles, California USA.
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authors.affiliation: LAS + USC Medical Centre, Los Angeles, California USA.
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authors.affiliation: LAS + USC Medical Centre, Los Angeles, California USA.
authors.forename: Demetrios
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authors.affiliation: Pediatric Intensive Care Unit, Hannover University Hospital, Hannover, Germany.
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authors.affiliation: Khuala Krai Hospital, Kuala Krai, Malaysia.
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authors.initials: AC
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authors.affiliation: Mansoura Faculty of Medicine, Mansoura, Egypt.
authors.forename: Wagih
authors.initials: W
authors.lastname: Ghannam
authors.affiliation: Medical University of Plovdiv, Plovdiv, Bulgaria.
authors.forename: Boris
authors.initials: B
authors.lastname: Sakakushev
authors.affiliation: Soroka Medical Centre, Beersheba, Israel.
authors.forename: Ohad
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authors.lastname: Guetta
authors.affiliation: University Hospital of Trauma, Tirana, Albania.
authors.forename: Agron
authors.initials: A
authors.lastname: Dogjani
authors.affiliation: Emergency and General Surgery, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy.
authors.forename: Stefano
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authors.lastname: Costa
authors.affiliation: Oxford University Hospital, Oxford, UK.
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authors.forename: Dimitrios
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authors.lastname: Damaskos
authors.affiliation: Erzincan University Faculty of Medicine Mengucek Gazi Training Research Hospital Erzincan, Erzincan, Turkey.
authors.forename: Arda
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authors.lastname: Isik
authors.affiliation: Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Kuo-Ching
authors.initials: KC
authors.lastname: Yuan
authors.affiliation: Ospedale Maggiore, Lodi, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Trotta
authors.affiliation: Ospedale di Circolo e Fondazione Macchi, University of Insubria, Varese, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Rausei
authors.affiliation: Hospital Universitario Doctor Peset, Valencia, Spain.
authors.forename: Aleix
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authors.affiliation: S.S. Annunziata Hospital, Taranto, Italy.
authors.forename: Giovanni
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authors.lastname: Bellanova
authors.affiliation: Hospital Santa Virgínia, São Paulo, Brazil.
authors.forename: Vinicius Cordeiro
authors.initials: VC
authors.lastname: Fonseca
authors.affiliation: Hospital Central Militar, Mexico City, Mexico.
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authors.initials: F
authors.lastname: Hernández
authors.affiliation: Tzaneio General Hospital of Piraeus, Piraeus, Greece.
authors.forename: Athanasios
authors.initials: A
authors.lastname: Marinis
authors.affiliation: Hospital Regional de Sao Jose, San Jose, Brazil.
authors.forename: Wellington
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authors.lastname: Fernandes
authors.affiliation: Hospital Santo Tomás, Panama City, Panama.
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authors.lastname: Quiodettis
authors.affiliation: Hadassah Hebrew University Medical Center, Jerusalem, Israel.
authors.forename: Miklosh
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authors.lastname: Bala
authors.affiliation: Department of Surgery, Medical School University Pécs, Pécs, Hungary.
authors.forename: Andras
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authors.lastname: Vereczkei
authors.affiliation: Hospital De Clinicas Da Unicamp, Campinas, Brazil.
authors.forename: Rafael L
authors.initials: RL
authors.lastname: Curado
authors.affiliation: Hospital De Clinicas Da Unicamp, Campinas, Brazil.
authors.forename: Gustavo Pereira
authors.initials: GP
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authors.affiliation: Hospital De Clinicas Da Unicamp, Campinas, Brazil.
authors.forename: Bruno M
authors.initials: BM
authors.lastname: Pereira
authors.affiliation: Vladimir City Clinical Hospital of Emergency Medicine, Vladimir City, Russia.
authors.forename: Mahir
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authors.lastname: Gachabayov
authors.affiliation: University Hospital, Cuenca, Ecuador.
authors.forename: Guillermo Perez
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authors.lastname: Chagerben
authors.affiliation: Hospital La Paz, Madrid, Spain.
authors.forename: Miguel Leon
authors.initials: ML
authors.lastname: Arellano
authors.affiliation: Adana Numune Training and Research Hospital, Department of Surgery, Adana, Turkey.
authors.forename: Sefa
authors.initials: S
authors.lastname: Ozyazici
authors.affiliation: Ospedale Sant' Andrea University Hospital Sapienza, Rome, Italy.
authors.forename: Gianluca
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authors.lastname: Costa
authors.affiliation: Baskent University School of Medicine, Ankara, Turkey.
authors.forename: Tugan
authors.initials: T
authors.lastname: Tezcaner
authors.affiliation: General, Emergency and Trauma Surgery Department, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127 Bergamo, Italy.
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mesh_terms: D000005:Abdomen / Q000601:surgery*; D058107:Abdominal Wound Closure Techniques / Q000639:trends; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D013505:Digestive System Surgical Procedures / Q000379:methods* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D038622:Internationality; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012042:Registries / Q000706:statistics & numerical data*; D014947:Wounds and Injuries / Q000601:surgery
keywords: Barker; Bogotà bag; Commercial; Compartment; IROA; Ischemia; Negative pressure; Non-commercial; Open abdomen; Peritonitis; Register; Skin; Trauma; Vascular emergencies; Witmann