title: 1,2,3-Triazolium-Based Peptoid Oligomers.
abstract: The cis-directing effect of the 1,2,3-triazolium-type side chain was studied on dimeric peptoid models with various patterns: αα, αβ, βα and ββ. Low influences of the sequence and of the solvent were observed, the cis conformation of the amide carrying the triazolium ranging from 83 to 94% in proportion. The synthesis of peptoid homooligomers with four or eight pendant 1,2,3-triazolium side chains is described. α-, β- and α,β-peptoids carrying propargyl groups were subjected to CuAAC reaction using alkyl azides, and the resulting triazoles were quaternized providing well-defined multitriazolium platforms. The influence of the counteranion (PF6-, BF4-or I-) on the conformation was also studied.
authors.affiliation: Université Clermont Auvergne , CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, F-63000 Clermont-Ferrand, France.|Laboratoire de Chimie Physique Moléculaire et Macromoléculaire, Département de Chimie, Faculté des Sciences, Université de Blida , I.B.P 270 Route de Soumaa, Blida, Algeria.
authors.forename: Hafida
authors.initials: H
authors.lastname: Aliouat
authors.affiliation: Université Clermont Auvergne , CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Caumes
authors.affiliation: Université Clermont Auvergne , CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Roy
authors.affiliation: Laboratoire de Chimie Physique Moléculaire et Macromoléculaire, Département de Chimie, Faculté des Sciences, Université de Blida , I.B.P 270 Route de Soumaa, Blida, Algeria.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Zouikri
authors.affiliation: Université Clermont Auvergne , CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
authors.forename: Claude
authors.initials: C
authors.lastname: Taillefumier
authors.affiliation: Université Clermont Auvergne , CNRS, SIGMA Clermont, Institut de Chimie de Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
authors.forename: Sophie
authors.identifier: 0000-0001-5033-9481
authors.initials: S
authors.lastname: Faure