title: Neurophysiological recovery 5 years after carpal tunnel release in patients with diabetes.
abstract: BACKGROUND
  The long-term results of neurophysiological recovery after carpal tunnel release in patients with diabetes have not been studied.
  
  
  METHODS
  Thirty-five patients with diabetes and carpal tunnel syndrome (CTS) were matched with 31 patients without diabetes who had idiopathic CTS, and 27 and 30 patients, respectively, participated in this follow-up study. Nerve conduction results at 5 years were compared with previously published results at baseline and 1 year.
  
  
  RESULTS
  Significant neurophysiological improvement continued from 1 to 5 years after carpal tunnel release for patients with and without diabetes. However, wrist-palm sensory conduction velocity was still abnormal for 85% and 43% of patients with and without diabetes, respectively. Although diabetes had an impact on 4 of 10 measured neurophysiological parameters, the influence of peripheral neuropathy seemed insignificant.
  
  
  CONCLUSIONS
  After carpal tunnel release, significant long-term neurophysiological improvement is possible for patients with diabetes, and it is not influenced by the presence of peripheral neuropathy. Muscle Nerve 56: E59-E64, 2017.
authors.affiliation: Department of Hand Surgery, Skåne University Hospital, SE-205 02, Malmö, Sweden.|Department of Translational Medicine, Hand Surgery, Lund University, Malmö, Sweden.
authors.forename: Niels O B
authors.initials: NOB
authors.lastname: Thomsen
authors.affiliation: Department of Clinical Neurophysiology, Skåne University Hospital, Lund, Sweden.|Department of Clinical Sciences Lund, Clinical Neurophysiology, Lund University, Lund, Sweden.
authors.forename: Gert S
authors.initials: GS
authors.lastname: Andersson
authors.affiliation: Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden.
authors.forename: Jonas
authors.initials: J
authors.lastname: Björk
authors.affiliation: Department of Hand Surgery, Skåne University Hospital, SE-205 02, Malmö, Sweden.|Department of Translational Medicine, Hand Surgery, Lund University, Malmö, Sweden.
authors.forename: Lars B
authors.initials: LB
authors.lastname: Dahlin
mesh_terms: D000328:Adult; D000368:Aged; D002349:Carpal Tunnel Syndrome / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery*; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology*; D010523:Peripheral Nervous System Diseases; D020127:Recovery of Function / Q000502:physiology*; D013997:Time Factors
keywords: carpal tunnel syndrome; diabetes; nerve conduction study; neuropathy; neurophysiology; peripheral nerve