title: A 4,5-quinolimide-based fluorescent sensor for the turn-on detection of Cd2+with live-cell imaging.
abstract: A 4,5-quinolimide derivative, BNA, bearing the amide-DPA receptor, was synthesized as a turn-on fluorescent sensor for Cd2+. Under physiological conditions, BNA could distinguish Cd2+from Zn2+, showing turn-on fluorescence behaviour and an increased fluorescence lifetime. BNA and Cd2+formed a 1 : 1 stoichiometric complex, and the detection limit was measured to be as low as 11 nM. Furthermore, BNA was utilized for fluorescence imaging of Cd2+in live cells. To the best of our knowledge, it is the first 4,5-quinolimide-based sensor for the detection of metal ions.
authors.affiliation: Key Laboratory of Fine Chemicals, College of Heilongjiang Province, Qiqihar University, Qiqihar 161006, China. xfguo@163.com jlh29@163.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Fine Chemicals, College of Heilongjiang Province, Qiqihar University, Qiqihar 161006, China. xfguo@163.com jlh29@163.com.
authors.forename: Xiangfeng
authors.identifier: http://orcid.org/0000-0002-3238-5908
authors.initials: X
authors.lastname: Guo
authors.affiliation: Key Laboratory of Fine Chemicals, College of Heilongjiang Province, Qiqihar University, Qiqihar 161006, China. xfguo@163.com jlh29@163.com.
authors.forename: Mengmeng
authors.initials: M
authors.lastname: Zheng
authors.affiliation: Key Laboratory of Fine Chemicals, College of Heilongjiang Province, Qiqihar University, Qiqihar 161006, China. xfguo@163.com jlh29@163.com.
authors.forename: Rui
authors.initials: R
authors.lastname: Yang
authors.affiliation: Key Laboratory of Fine Chemicals, College of Heilongjiang Province, Qiqihar University, Qiqihar 161006, China. xfguo@163.com jlh29@163.com.
authors.forename: Hongming
authors.initials: H
authors.lastname: Yang
authors.affiliation: Key Laboratory of Fine Chemicals, College of Heilongjiang Province, Qiqihar University, Qiqihar 161006, China. xfguo@163.com jlh29@163.com.
authors.forename: Lihua
authors.initials: L
authors.lastname: Jia
authors.affiliation: Key Laboratory of Fine Chemicals, College of Heilongjiang Province, Qiqihar University, Qiqihar 161006, China. xfguo@163.com jlh29@163.com.
authors.forename: Mengmeng
authors.initials: M
authors.lastname: Yang
mesh_terms: D002104:Cadmium / Q000032:analysis*; D005456:Fluorescent Dyes / Q000032:analysis / Q000138:chemical synthesis / Q000737:chemistry*; D050296:Microbial Viability; D011804:Quinolines / Q000032:analysis / Q000138:chemical synthesis / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000166:cytology*
chemical_list: C000626187:4,5-quinolimide; D005456:Fluorescent Dyes; D011804:Quinolines; D002104:Cadmium