title: Neurological Complications of the Leukemias Across the Ages.
abstract: Acute and chronic leukemias are heterogeneous diseases and can affect any part of the body upon initial discovery. Understanding the sequela of systemic involvement is key for proper diagnosis and treatment.
  
  
  
  Over the decades, new research has emerged regarding neurological complications of the myeloid or lymphoid leukemias. Central nervous system involvement usually confers a poor prognosis and requires emergent treatment. Standard of care still involves systemic therapy, intrathecal administration of chemotherapeutic agents, and cranial radiation. Treatment-related side effects can occur and need to be recognized by any practitioner involved with patient care. It is imperative to understand neurologic complications from leukemia to prevent delays and initiate necessary treatment to maintain neurologic and cognitive function.
authors.affiliation: Loyola University Medical Center, Maywood, IL, USA. STEPHANIE.BERG@lumc.edu.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Berg
authors.affiliation: Loyola University Medical Center, Maywood, IL, USA.
authors.forename: Sucha
authors.initials: S
authors.lastname: Nand
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D004358:Drug Therapy; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007938:Leukemia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy; D009422:Nervous System Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy
chemical_list: D000970:Antineoplastic Agents
keywords: Central nervous system; Intrathecal; Lymphoblastic leukemia; Lymphocytic leukemia; Myeloid leukemia; Neurologic complications