title: Is sedentary behaviour unhealthy and if so, does reducing it improve this?
abstract: OBJECTIVE
  To provide a qualitative synthesis of the available literature on the role of sedentary behavior in health.
  
  
  OBJECTIVE
  We sought to determine if (i) being sedentary 'causes' health problems and (ii) interventions to reduce sedentary behavior improve health status.
  
  
  METHODS
  PubMed and Google Scholar databases were utilized. Manuscripts published from 2001 to 2015 using specific keyword combinations (eg sedentary behavior, physical activity, sitting, intervention) were included and qualitatively reviewed.
  
  
  RESULTS
  Data is suggestive of an association of sedentary behavior and negative health indicators. The association between sedentary behavior and mortality is stronger. There is some limited evidence suggesting short-term health benefit to reducing sedentary behavior.
  
  
  CONCLUSIONS
  Evidence linking sedentary behavior to negative health outcomes is incomplete and often largely associational in nature thus not allowing for causal inference. In addition, interventional literature frequently fails to measure health outcomes, relying instead on the erroneous endpoint of changing sedentary behavior alone.
  
  
  CONCLUSIONS
  Taken as a whole the literature is suggestive that there may be value in reducing sedentary behavior to have modest impact on health. However, the magnitude of the benefit appears minor and must be considered before making largescale and potentially costly clinical and public health recommendations.
authors.affiliation: Department of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Chin
authors.affiliation: Department of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.
authors.forename: Chanaka
authors.identifier: http://orcid.org/0000-0003-2049-4901
authors.initials: C
authors.lastname: Kahathuduwa
authors.affiliation: Department of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.
authors.forename: Martin
authors.initials: M
authors.lastname: Binks
mesh_terms: D002318:Cardiovascular Diseases / Q000209:etiology; D019317:Evidence-Based Medicine; D015444:Exercise / Q000502:physiology; D006293:Health Promotion; D006305:Health Status Indicators; D006801:Humans; D009043:Motor Activity; D009765:Obesity / Q000209:etiology; D057185:Sedentary Behavior