title: New Benzodioxole Compounds from the Root Extract ofAstrodaucus persicus.
abstract: There are many efforts for identification of natural compounds from dietary or medicinal plants. Young roots and aerial parts ofA. persicushave been used as food additive or salad vegetable in some parts of Iran. In this study, different fractions of the root extract ofA. persicuswere subjected for isolation and purification of secondary metabolites. The methanol extract of the roots was fractionated with hexane (HE), chloroform (CL), ethyl acetate (EA) and methanol (ME). Five novel compounds were isolated from HE, CL and EA using different chromatographic techniques and were identified by1H-NMR,13C-NMR, 2D-NMR and MS spectroscopic methods. Elucidated compounds with benzodioxole structure were characterized for the first time as 5-((propanoyl methyl)amino)-4,7-dimethoxybenzo[d][1,3]dioxole (1), 5-(3-ethyloxiran-2-yloxy)-4,7-dimethoxybenzo[d][1,3]dioxole (2), 4,7-dimethoxy-5-(propanonyl) benzo[d][1,3]dioxole (3), 4-ethoxybenzo[d][1,3]dioxol-6-carbaldehyde (4), and 4-(O-β-D-glucopyranosyl)-6-(3-propanyloxiran-2-yloxy)benzo[d][1,3]dioxole (5).
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Saied
authors.initials: S
authors.lastname: Goodarzi
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Hadjiakhoondi
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Narguess
authors.initials: N
authors.lastname: Yassa
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mahnaz
authors.initials: M
authors.lastname: Khanavi
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Tofighi
keywords: Apiaceae; Astrodaucus persicus; Benzodioxole structures; Phytochemistry; Root