title: Multicenter experiences in temporal bone cancer surgery based on 89 cases.
abstract: OBJECTIVE
  To present outcomes of extensive surgery: lateral, subtotal, total petrosectomies in patients with temporal bone invasion resulting from specific primary cancers.
  
  
  METHODS
  Retrospective case review.
  
  
  METHODS
  Four tertiary referral centers.
  
  
  METHODS
  89 patients with cancer of the temporal bone treated between January 2006 and December 2010.
  
  
  METHODS
  Multidisciplinary team approach including surgical resection, reconstruction, and postoperative radiotherapy.
  
  
  METHODS
  Disease-specific survival, overall survival.
  
  
  RESULTS
  In 27.0% of the patients, relapse was reported, with an average of 6.3 months after surgery; 31 patients (34.8%) died during the follow-up. The average mortality was 22.1 months. Fifty-four patients (58.7%) stayed alive during the time of observation. The average survival time was 42.0 months. The median time of survival with relapse was 12 months (range: 1-51 months). The three-year disease-free rate was 38.0% and the overall survival rate was 58.7%.
  
  
  CONCLUSIONS
  Petrosectomy is an effective treatment for malignant temporal bone invasion. The probability of a good outcome was statistically decreased with a high T grade, positive margins, and salvage surgery. Younger age is connected with better prognosis. One of the major tasks remains to improve detection and to shorten the time to diagnosis, keeping in mind that symptoms are insidious and in younger people, the time before diagnosis was longer.
authors.affiliation: ENT Department, Medical University, Poznań, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Wierzbicka
authors.affiliation: ENT Department, Medical University, Warsaw, Poland.
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Niemczyk
authors.affiliation: ENT Department, Medical University, Warsaw, Poland.
authors.forename: Antoni
authors.initials: A
authors.lastname: Bruzgielewicz
authors.affiliation: ENT Department, Medical University, Łódź, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Durko
authors.affiliation: ENT Department, Medical University, Lublin, Poland.
authors.forename: Janusz
authors.initials: J
authors.lastname: Klatka
authors.affiliation: ENT Department, Medical University, Poznań, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Kopeć
authors.affiliation: ENT Department, Medical University, Warsaw, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Osuch-Wójcikiewicz
authors.affiliation: ENT Department, Medical University, Łódź, Poland.
authors.forename: Wioletta
authors.initials: W
authors.lastname: Pietruszewska
authors.affiliation: ENT Department, Medical University, Lublin, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Szymański
authors.affiliation: ENT Department, Medical University, Poznań, Poland.
authors.forename: Witold
authors.initials: W
authors.lastname: Szyfter
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003528:Carcinoma, Adenoid Cystic / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures; D011379:Prognosis; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D013701:Temporal Bone / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome