title: FIGO stage IB1 cervical carcinoma: Place and principles of brachytherapy.
abstract: The treatment of cervical cancers according to FIGO staging is well defined. For FIGO stage IB2 or more, chemoradiotherapy followed by uterovaginal brachytherapy boost is the standard treatment. Surgery is the preferred choice for less advanced tumors. However, most French institutions propose preoperative brachytherapy followed by hysterectomy with pelvic lymphadenectomy for FIGO stage IB1 tumors over 2cm. Brachytherapy is also used for the boost after adjuvant pelvic external beam radiotherapy. Tridimensional dosimetry with optimization allows better treatment planning, delivering high doses to target volumes with limited irradiation to the organs at risk. We will discuss the indications of brachytherapy for FIGO stage IB1 tumors and the principles of pulsed-dose rate and high-dose rate techniques.
authors.affiliation: Department of Radiotherapy, Institut de cancérologie de Lorraine, 6, avenue de Bourgogne, 54500 Vandœuvre-lès-Nancy, France. Electronic address: huertas@hotmail.fr.
authors.forename: A
authors.initials: A
authors.lastname: Huertas
authors.affiliation: Department of Radiotherapy, Institut de cancérologie de Lorraine, 6, avenue de Bourgogne, 54500 Vandœuvre-lès-Nancy, France.
authors.forename: S
authors.initials: S
authors.lastname: Oldrini
authors.affiliation: Department of Radiotherapy, Institut de cancérologie de Lorraine, 6, avenue de Bourgogne, 54500 Vandœuvre-lès-Nancy, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Nesseler
authors.affiliation: Department of Radiotherapy, Institut de cancérologie de Lorraine, 6, avenue de Bourgogne, 54500 Vandœuvre-lès-Nancy, France.
authors.forename: F
authors.initials: F
authors.lastname: Courrech
authors.affiliation: Department of Radiotherapy, Mercy Hospital, centre hospitalier régional de Metz-Thionville, 1, allée du Château, 57530 Ars-Laquenexy, France.
authors.forename: P
authors.initials: P
authors.lastname: Rétif
authors.affiliation: Department of Radiotherapy, Institut de cancérologie de Lorraine, 6, avenue de Bourgogne, 54500 Vandœuvre-lès-Nancy, France.
authors.forename: C
authors.initials: C
authors.lastname: Charra-Brunaud
authors.affiliation: Department of Radiotherapy, Institut de cancérologie de Lorraine, 6, avenue de Bourgogne, 54500 Vandœuvre-lès-Nancy, France.
authors.forename: D
authors.initials: D
authors.lastname: Peiffert
mesh_terms: D001918:Brachytherapy / Q000379:methods; D003131:Combined Modality Therapy; D003663:Decision Trees; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000532:radiotherapy* / Q000601:surgery
keywords: Brachytherapy; Cancer du col utérin; Cervical cancer; Colpohystérectomie; Curiethérapie; HDR; Hysterectomy; Optimization; PDR