title: Relapsing bullous amyloidosis of the oral mucosa and acquired cutis laxa in a patient with multiple myeloma: a rare triple association.
abstract: It is well known that primary systemic amyloidosis [light chain (AL) amyloidosis] is associated with hidden dyscrasia or multiple myeloma. Acquired cutis laxa (cutis laxa acquisita; CLA) has also been described in patients with plasma cell dyscrasias, including multiple myeloma. We report a case in which haemorrhagic oral bullae were the first sign of an undiagnosed primary systemic amyloidosis related to multiple myeloma IgG-λ and previously diagnosed CLA. There is only one report in literature of this rare triple association; however, in that case the patient did not have oral mucosal involvement or bullous amyloidosis.
authors.affiliation: Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Gonzalez-Ramos
authors.affiliation: Department of Dermatopathology, Hospital Universitario La Paz, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Garrido-Gutiérrez
authors.affiliation: Department of Dermatology, Hospital Universitario Infanta Sofia, San Sebastian de los Reyes, Madrid, Spain.
authors.forename: Y
authors.initials: Y
authors.lastname: González-Silva
authors.affiliation: Primary Care Medicine, Centro de salud Plaza del Ejercito, Valladolid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Yébenes-Gregorio
authors.affiliation: Primary Care Medicine, Centro de salud Plaza del Ejercito, Valladolid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Beato-Merino
authors.affiliation: Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Vidaurrázaga-Arcaya
authors.affiliation: Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Herranz-Pinto