title: Acupuncture therapy in the management of the clinical outcomes for temporomandibular disorders: A PRISMA-compliant meta-analysis.
abstract: OBJECTIVE
  The purpose of this study was to evaluate conventional acupuncture therapy in the management of clinical outcomes for temporomandibular disorders (TMD) in adults.
  
  
  METHODS
  The electronic databases PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and Clinical Trails.gov were searched for reports published until March 31, 2016.
  
  
  RESULTS
  Nine eligible studies from 8 publications involving 231 patients were included in the meta-analysis. A comparison of the main outcome of visual analog scale (VAS) values of pain between the acupuncture group and control group showed a significant decrease (MD = -0.98, 95% CI [-1.62, -0.34], I=54%, P = 0.003) in the VAS following acupuncture treatment. However, subgroup analysis according to the type of sham control group indicated that there were significant differences in the results when sham acupuncture was used as the control group (MD = -1.54, 95% CI [-2.63, -0.45], I=58%, P = 0.006) as well as when sham laser treatment was used as the control group (MD = -1.29, 95% CI [-2.32, -0.27], I = 0%, P = 0.01). However, there was no significant difference when the splint treatment group was used as the control group (MD = -0.09, 95% CI [-0.69, 0.50], I = 0%, P = 0.76). Subgroup analyses of VAS for pain by the classification of diseases indicated that the myogenous TMD subgroup demonstrated a significant difference (MD = -1.49, 95% CI [-2.45, -0.53], I = 47%, P = 0.002), and TMD showed no statistically significant difference (MD = -0.42, 95% CI [-1.14, 0.30], I = 46%, P = 0.25). Subgroup analysis according to whether the subgroup penetrated the skin showed that nonpenetrating sham acupuncture as the control group showed a significant difference (MD = -1.56, 95% CI [-2.70, -0.41], I = 58%, P = 0.008) compared with the conventional acupuncture as the treatment modality, while penetrating sham acupuncture as the control group showed no significant difference (MD = -1.29, 95% CI [-3.40, 0.82], I = not applicable, P = 0.23). No publication bias was observed considering the symmetry of the funnel plots.
  
  
  CONCLUSIONS
  Our results indicate that conventional acupuncture therapy is effective in reducing the degree of pain in patients with TMD, especially those with myofascial pain symptoms.
authors.affiliation: Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital School of Stomatology Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine, Ministry of Education, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, No. 237, Luoyu Road, Wuhan, China.
authors.forename: Jun-Yi
authors.initials: JY
authors.lastname: Wu
authors.forename: Chao
authors.initials: C
authors.lastname: Zhang
authors.forename: Yang-Peng
authors.initials: YP
authors.lastname: Xu
authors.forename: Ya-Yu
authors.initials: YY
authors.lastname: Yu
authors.forename: Le
authors.initials: L
authors.lastname: Peng
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Leng
authors.forename: Yu-Ming
authors.initials: YM
authors.lastname: Niu
authors.forename: Mo-Hong
authors.initials: MH
authors.lastname: Deng
mesh_terms: D015670:Acupuncture Therapy; D006801:Humans; D013705:Temporomandibular Joint Disorders / Q000628:therapy*; D016896:Treatment Outcome; D064232:Visual Analog Scale