title: Use of Pre-exposure Prophylaxis (PrEP) in Young Men Who Have Sex with Men is Associated with Race, Sexual Risk Behavior and Peer Network Size.
abstract: Pre-exposure prophylaxis (PrEP) is efficacious to prevent HIV infection, however, uptake among young men who have sex with men (YMSM) is relatively low. The purpose of this study was to describe PrEP use and related factors in a representative sample of YMSM in two cities, Chicago and Houston. YMSM, ages 16-29, were recruited via respondent-driven sampling (RDS) from 2014 to 2016. Correlates of PrEP uptake were assessed in weighted multivariable logistic regression models. A total of 12.2% of participants (of 394) reported ever taking PrEP; Black YMSM had the lowest rates of uptake (4.7%) and Whites the highest (29.5%). In a multivariable regression model, having an HIV positive sex partner, reporting recent group sex, peer network size, and city (Chicago) were significantly and positively associated with use of PrEP, while Black race was negatively associated with it. Given evidence of racial/ethnic disparities in PrEP uptake in this study, further research is needed to identify potential mechanisms of action and points of intervention.
authors.affiliation: Division of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, 225 E. Chicago Avenue, Box 161, Chicago, IL, 60611, USA. lkuhns@luriechildrens.org.|Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. lkuhns@luriechildrens.org.
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Kuhns
authors.affiliation: Division of Epidemiology & Biostatistics, University of Illinois at Chicago School of Public Health, Chicago, IL, USA.
authors.forename: Anna L
authors.initials: AL
authors.lastname: Hotton
authors.affiliation: Chicago Center for HIV Elimination, University of Chicago, Chicago, IL, USA.|Department of Medicine, University of Chicago, Chicago, IL, USA.|Department of Public Health Sciences, University of Chicago, Chicago, IL, USA.
authors.forename: John
authors.initials: J
authors.lastname: Schneider
authors.affiliation: Division of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, 225 E. Chicago Avenue, Box 161, Chicago, IL, 60611, USA.|Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Garofalo
authors.affiliation: Department of Health Promotion & Behavioral Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, USA.
authors.forename: Kayo
authors.initials: K
authors.lastname: Fujimoto
mesh_terms: D000328:Adult; D001741:Black or African American / Q000523:psychology / Q000706:statistics & numerical data; D044383:Black People / Q000523:psychology / Q000706:statistics & numerical data*; D002641:Chicago; D015658:HIV Infections / Q000517:prevention & control*; D017048:Health Care Costs; D006297:Health Services Accessibility; D006630:Hispanic or Latino / Q000523:psychology / Q000706:statistics & numerical data; D018451:Homosexuality, Male / Q000208:ethnology* / Q000523:psychology / Q000706:statistics & numerical data; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010342:Patient Acceptance of Health Care / Q000208:ethnology / Q000706:statistics & numerical data*; D010379:Peer Group; D065129:Pre-Exposure Prophylaxis / Q000706:statistics & numerical data*; D044469:Racial Groups; D012309:Risk-Taking; D012747:Sexual Partners; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D013781:Texas; D044465:White People / Q000523:psychology / Q000706:statistics & numerical data; D055815:Young Adult
keywords: HIV prevention; Pre-exposure prophylaxis; Social network; Young men who have sex with men