title: Young Women With Acute Myocardial Infarction: Current Perspectives.
abstract: In recent years, there has been growing public awareness and increasing attention to young women with acute myocardial infarction (AMI), who represent an extreme phenotype. Young women presenting with AMI may develop coronary disease by different mechanisms and often have worse recoveries, with higher risk for morbidity and mortality compared with similarly aged men. The purpose of this cardiovascular perspective piece is to review recent studies of AMI in young women. More specifically, we emphasize differences in the epidemiology, diagnosis, and management of AMI in young women (when compared with men) across the continuum of care, including their pre-AMI, in-hospital, and post-AMI periods, and highlight gaps in knowledge and outcomes that can inform the next generation of research.
authors.affiliation: From the Center for Outcomes Research and Evaluation (CORE), New Haven, CT (R.P.D., E.S.S., H.M.K.); Department of Emergency Medicine (R.P.D., B.S., G.D.) and Section of Cardiovascular Medicine (C.S., E.S.S., H.M.K.), Yale University School of Medicine, New Haven, CT; Section of Cardiovascular Medicine and the Robert Wood Johnson Foundation, New Haven, CT (H.M.K.); and Department of Health Policy and Management, Yale School of Public Health, New Haven, CT (H.M.K.). rachel.dreyer@yale.edu.
authors.forename: Rachel P
authors.initials: RP
authors.lastname: Dreyer
authors.affiliation: From the Center for Outcomes Research and Evaluation (CORE), New Haven, CT (R.P.D., E.S.S., H.M.K.); Department of Emergency Medicine (R.P.D., B.S., G.D.) and Section of Cardiovascular Medicine (C.S., E.S.S., H.M.K.), Yale University School of Medicine, New Haven, CT; Section of Cardiovascular Medicine and the Robert Wood Johnson Foundation, New Haven, CT (H.M.K.); and Department of Health Policy and Management, Yale School of Public Health, New Haven, CT (H.M.K.).
authors.forename: Christopher
authors.initials: C
authors.lastname: Sciria
authors.affiliation: From the Center for Outcomes Research and Evaluation (CORE), New Haven, CT (R.P.D., E.S.S., H.M.K.); Department of Emergency Medicine (R.P.D., B.S., G.D.) and Section of Cardiovascular Medicine (C.S., E.S.S., H.M.K.), Yale University School of Medicine, New Haven, CT; Section of Cardiovascular Medicine and the Robert Wood Johnson Foundation, New Haven, CT (H.M.K.); and Department of Health Policy and Management, Yale School of Public Health, New Haven, CT (H.M.K.).
authors.forename: Erica S
authors.initials: ES
authors.lastname: Spatz
authors.affiliation: From the Center for Outcomes Research and Evaluation (CORE), New Haven, CT (R.P.D., E.S.S., H.M.K.); Department of Emergency Medicine (R.P.D., B.S., G.D.) and Section of Cardiovascular Medicine (C.S., E.S.S., H.M.K.), Yale University School of Medicine, New Haven, CT; Section of Cardiovascular Medicine and the Robert Wood Johnson Foundation, New Haven, CT (H.M.K.); and Department of Health Policy and Management, Yale School of Public Health, New Haven, CT (H.M.K.).
authors.forename: Basmah
authors.initials: B
authors.lastname: Safdar
authors.affiliation: From the Center for Outcomes Research and Evaluation (CORE), New Haven, CT (R.P.D., E.S.S., H.M.K.); Department of Emergency Medicine (R.P.D., B.S., G.D.) and Section of Cardiovascular Medicine (C.S., E.S.S., H.M.K.), Yale University School of Medicine, New Haven, CT; Section of Cardiovascular Medicine and the Robert Wood Johnson Foundation, New Haven, CT (H.M.K.); and Department of Health Policy and Management, Yale School of Public Health, New Haven, CT (H.M.K.).
authors.forename: Gail
authors.initials: G
authors.lastname: D'Onofrio
authors.affiliation: From the Center for Outcomes Research and Evaluation (CORE), New Haven, CT (R.P.D., E.S.S., H.M.K.); Department of Emergency Medicine (R.P.D., B.S., G.D.) and Section of Cardiovascular Medicine (C.S., E.S.S., H.M.K.), Yale University School of Medicine, New Haven, CT; Section of Cardiovascular Medicine and the Robert Wood Johnson Foundation, New Haven, CT (H.M.K.); and Department of Health Policy and Management, Yale School of Public Health, New Haven, CT (H.M.K.).
authors.forename: Harlan M
authors.initials: HM
authors.lastname: Krumholz
mesh_terms: D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D005260:Female; D054624:Health Status Disparities; D054625:Healthcare Disparities; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D015995:Prevalence; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
keywords: coronary artery disease; myocardial infarction; phenotype; prevalence