title: Copper-Catalyzed Selenylation of Imidazo[1,2-a]pyridines with Selenium Powder via a Radical Pathway.
abstract: A convenient and efficient approach for the formation of nitrogen heterocycle-fused imidazo[1,2-a]pyridine and benzo[b]selenophenes has been developed through copper-catalyzed direct selenylation of readily available 2-(2-bromophenyl)imidazo[1,2-a]pyridines via regioselective cleavage of C(sp2)-Br and C(sp2)-H bonds using readily available selenium powder as the selenylating reagents under ligand- and base-free conditions in air. Preliminary mechanistic investigations indicated that radical species were involved in the present transformation.
authors.affiliation: Institute of Medicine and Materials Applied Technologies, School of Chemistry and Chemical Engineering, Qufu Normal University , Qufu 273165, Shandong, P. R. China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Sun
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University , Beijing 100084, China.
authors.forename: Min
authors.initials: M
authors.lastname: Jiang
authors.affiliation: Institute of Medicine and Materials Applied Technologies, School of Chemistry and Chemical Engineering, Qufu Normal University , Qufu 273165, Shandong, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.affiliation: Laboratory and Equipment Management Department, Qufu Normal University , Qufu 273165, Shandong, P. R. China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Min
authors.affiliation: Institute of Medicine and Materials Applied Technologies, School of Chemistry and Chemical Engineering, Qufu Normal University , Qufu 273165, Shandong, P. R. China.
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Institute of Medicine and Materials Applied Technologies, School of Chemistry and Chemical Engineering, Qufu Normal University , Qufu 273165, Shandong, P. R. China.
authors.forename: Wanhui
authors.initials: W
authors.lastname: Li
authors.affiliation: Institute of Medicine and Materials Applied Technologies, School of Chemistry and Chemical Engineering, Qufu Normal University , Qufu 273165, Shandong, P. R. China.
authors.forename: Daoshan
authors.initials: D
authors.lastname: Yang
authors.affiliation: Institute of Medicine and Materials Applied Technologies, School of Chemistry and Chemical Engineering, Qufu Normal University , Qufu 273165, Shandong, P. R. China.
authors.forename: Hua
authors.identifier: 0000-0003-0728-8986
authors.initials: H
authors.lastname: Wang