title: Palladium-catalyzed cascade metallo-ene/Suzuki coupling reaction of allenamides.
abstract: A new type of cascade metallo-ene/Suzuki coupling reaction of allenamides catalyzed by palladium is described. A variety of polyfunctionalized 2,3-dihydropyrrole derivatives, which are important structural motifs for bioactive molecules, were furnished with excellent yields. Two new Csp3-Csp2bonds were constructed in one pot efficiently. The reductive elimination from π-allyl palladium complex presented excellent regioselectivity to the terminal C1 position. The unique terminal alkene was one of the most easily functionalized groups, providing these molecules with a potential transformation to much more complicated molecules.
authors.affiliation: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors.forename: Hanbing
authors.initials: H
authors.lastname: Liang
authors.affiliation: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors.forename: Fachao
authors.initials: F
authors.lastname: Yan
authors.affiliation: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors.forename: Xu
authors.initials: X
authors.lastname: Dong
authors.affiliation: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.affiliation: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Wei
authors.affiliation: The Technical Center of Zibo Entry and Exit Inspection and Quarantine Bureau, Zibo 255031, P. R. China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Liu
authors.affiliation: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors.forename: Yunhui
authors.initials: Y
authors.lastname: Dong
authors.affiliation: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com and The Technical Center of Zibo Entry and Exit Inspection and Quarantine Bureau, Zibo 255031, P. R. China and College of Materials Science and Engineering, Hunan University, Changsha, Hunan 410082, China.
authors.forename: Hui
authors.identifier: http://orcid.org/0000-0001-8916-6055
authors.initials: H
authors.lastname: Liu