title: Primary Pulmonary Lymphoepithelioma-like Carcinoma on FDG PET/CT.
abstract: A 69-year-old male smoker was referred to18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) with the indication of a suspicious solitary pulmonary nodule. FDG PET/CT determined a 2.5 × 2-cm soft-tissue lesion (SUVmax, 16.2) with spiculated margins in the hilum of the right lung. A 1-cm diameter lymphadenopathy on the right hilum with an SUVmax of 3.2 was also determined. Transbronchial biopsy of the right hilar lymphadenopathy did not reveal any malignant features in histopathologic examination, and it was determined to be reactive. The patient underwent a right upper lobe segmentectomy, and the histopathologic evaluation revealed that the tumor was a primary lymphoepithelioma-like carcinoma (LELC) of the lung with negative Epstein-Barr virus (EBV) on in situ hybridization studies. In this case report, we mainly focus on the FDG avidity of this very rare kind of tumor comparatively with previous reports and possible explanations of discordancy in FDG avidity in relation to histopathologic characteristics.
authors.affiliation: Department of Nuclear Medicine, Trakya University Medical Faculty, 22030 Edirne, Turkey.
authors.forename: Gul Ege
authors.initials: GE
authors.lastname: Aktas
authors.affiliation: Department of Pathology, Trakya University Medical Faculty, 22030 Edirne, Turkey.
authors.forename: Nuray
authors.initials: N
authors.lastname: Can
authors.affiliation: Department of Nuclear Medicine, Trakya University Medical Faculty, 22030 Edirne, Turkey.
authors.forename: Selin Soyluoglu
authors.initials: SS
authors.lastname: Demir
authors.affiliation: Department of Nuclear Medicine, Trakya University Medical Faculty, 22030 Edirne, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Sarıkaya
keywords: FDG; Lung cancer; Lymphoepithelioma-like carcinoma; PET/CT; SUV