title: Imminent fracture risk.
abstract: The clinical significance of osteoporosis is in the occurrence of fractures and re-fractures. The main risk factor of sustaining a fracture is a previous one, but a recent fracture is a better fracture risk factor than fracture history. The role of the recency of fracture has been shown for both vertebral and non-vertebral fracture risk. This imminent risk is explained by both bone-related factors (underlying osteoporosis) and fall-related factors (including those related to postfracture care). Such a short-term increased risk has been shown also in patients initiating corticosteroids and in frail osteoporotic subjects with central nervous system (CNS) diseases or drugs targeting CNS, and thus a high risk of falls. Patients with an imminent (i.e. 2 years) risk of fracture or refracture should be identified in priority in order to receive an immediate treatment and a program of fall prevention.
authors.affiliation: Paris Descartes University, Paris, France. christian.roux@aphp.fr.|Epidemiology and Biostatistics Sorbonne Paris Cité Research Center, UMR U1153, Paris, France. christian.roux@aphp.fr.|Department of Rheumatology, Cochin Hospital, Assistance-Publique-Hôpitaux de Paris, Paris, France. christian.roux@aphp.fr.
authors.forename: C
authors.initials: C
authors.lastname: Roux
authors.affiliation: Epidemiology and Biostatistics Sorbonne Paris Cité Research Center, UMR U1153, Paris, France.|Department of Rheumatology, Cochin Hospital, Assistance-Publique-Hôpitaux de Paris, Paris, France.
authors.forename: K
authors.initials: K
authors.lastname: Briot
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D000367:Age Factors; D015519:Bone Density; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000503:physiopathology; D058866:Osteoporotic Fractures / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D012008:Recurrence; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors
keywords: Fracture; Imminent; Osteoporosis; Treatment