title: Physical activity and lung cancer risk in men and women.
abstract: Although evidence has accumulated that recreational physical activities (PA) may reduce lung cancer risk, there is little evidence concerning the possible role of a potentially more important source of PA, namely occupational PA. We investigated both recreational and lifetime occupational PA in relation to lung cancer risk in a population-based case-control study in Montreal, Canada (NCASES= 727; NCONTROLS= 1,351).
  
  
  
  Unconditional logistic regression was used to estimate odds ratios (OR), separately for men and women, adjusting for smoking, exposure to occupational carcinogens, and sociodemographic and lifestyle factors.
  
  
  
  In both sexes, increasing recreational PA was associated with a lower lung cancer risk (ORMEN= 0.66, 95% confidence interval (CI) 0.47-0.92; ORWOMEN= 0.55, 95% CI 0.34-0.88, comparing the highest versus lowest tertiles). For occupational PA, no association was observed among women, while increasing occupational PA was associated with increased risk among men (ORMEN= 1.96, 95% CI 1.27-3.01). ORs were not modified by occupational lung carcinogen exposure, body mass index, and smoking level; results were similar across lung cancer histological types.
  
  
  
  Our results support the previous findings for recreational PA and lung cancer risk. Unexpectedly, our findings suggest a positive association for occupational PA; this requires replication and more detailed investigation.
authors.affiliation: Department of Social and Preventive Medicine and CRCHUM (Centre de recherche du CHUM), Université de Montréal, 850 Saint-Denis Street, Montréal, QC, Canada.
authors.forename: Vikki
authors.initials: V
authors.lastname: Ho
authors.affiliation: INRS (Institut Armand-Frappier Research Center), Laval, QC, Canada.|CRCHUM (Centre de recherche du CHUM), Montréal, QC, Canada.
authors.forename: Marie-Elise
authors.initials: ME
authors.lastname: Parent
authors.affiliation: CRCHUM (Centre de recherche du CHUM), Montréal, QC, Canada.
authors.forename: Javier
authors.initials: J
authors.lastname: Pintos
authors.affiliation: Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, QC, Canada.
authors.forename: Michal
authors.initials: M
authors.lastname: Abrahamowicz
authors.affiliation: Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, QC, Canada.
authors.forename: Coraline
authors.initials: C
authors.lastname: Danieli
authors.affiliation: CRCHUM (Centre de recherche du CHUM), Montréal, QC, Canada.
authors.forename: Lesley
authors.initials: L
authors.lastname: Richardson
authors.affiliation: INRS (Institut Armand-Frappier Research Center), Laval, QC, Canada.
authors.forename: Robert
authors.initials: R
authors.lastname: Bourbonnais
authors.affiliation: Department of Social and Preventive Medicine and CRCHUM (Centre de recherche du CHUM), Université de Montréal, 850 Saint-Denis Street, Montréal, QC, Canada.
authors.forename: Lise
authors.initials: L
authors.lastname: Gauvin
authors.affiliation: Department of Social and Preventive Medicine and CRCHUM (Centre de recherche du CHUM), Université de Montréal, 850 Saint-Denis Street, Montréal, QC, Canada.
authors.forename: Jack
authors.initials: J
authors.lastname: Siemiatycki
authors.affiliation: Department of Social and Preventive Medicine and CRCHUM (Centre de recherche du CHUM), Université de Montréal, 850 Saint-Denis Street, Montréal, QC, Canada. anita.koushik@umontreal.ca.
authors.forename: Anita
authors.initials: A
authors.lastname: Koushik
mesh_terms: D000368:Aged; D002170:Canada; D016022:Case-Control Studies; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008019:Life Style; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D065840:Protective Factors; D011998:Recreation; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*
keywords: Case–control studies; Exercise; Histology; Lung neoplasms; Motor activity; Occupation; Recreation