title: Spatial Analysis of Regional Factors and Lung Cancer Mortality in China, 1973-2013.
abstract: Background:China's lung cancer crude death rate has increased 6.9-fold from 1973 to 2014. During this time, the country experienced extremely rapid economic growth and social change. It is important to understand the effects of risk factors on lung cancer mortality (LCM) for better allocation of limited resources of cancer prevention and control in China.Methods:Using three nationwide mortality surveys from 1973 to 2005, Global Health Data Exchange data in 2013, three nationwide smoking surveys from 1984 to 2013, four population censuses from 1964 to 2000, and other datasets, we have compiled datasets and developed spatial random effect models to assess the association of various area-level-contributing factors on LCM. Spatial scan statistics are used to detect high-risk clusters of LCM.Results:LCM is higher in urban and more industrialized areas (RR = 1.17) compared with those in rural areas. The level of industrial development's effect is higher for men, which accounts for about 70% of all LCM. Smoking is positively associated with regional variation of LCM rates, and the effect is higher for women than for men.Conclusions:The geographic pattern of high LCM in China is different from that of Western countries. LCM is positively associated with higher socioeconomic status, with more urbanized areas at a higher level of industrial development.Impact:There is a need to further explore additional risk in the high-risk clusters. The study is about China, but this situation may happen in other countries experiencing rapid industrialization and other developing countries.Cancer Epidemiol Biomarkers Prev; 26(4); 569-77. ©2017 AACRSee all the articles in thisCEBP Focussection, "Geospatial Approaches to Cancer Control and Population Sciences."
authors.affiliation: Department of Geography, Central Connecticut State University, New Britain, Connecticut.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Shen
authors.affiliation: Division of Surveillance, National Center for Chronic Non-Communicable Diseases Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), Beijing, P.R. China.
authors.forename: Limin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Surveillance Research Program, Division of Cancer Control and Population Sciences, NCI, NIH, Bethesda, Maryland. li.zhu@nih.gov.
authors.forename: Li
authors.initials: L
authors.lastname: Zhu
mesh_terms: D002681:China / Q000453:epidemiology; D003710:Demography / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000401:mortality*; D008297:Male; D011159:Population Surveillance; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012907:Smoking / Q000453:epidemiology; D012923:Social Class; D014505:Urban Population; D014507:Urbanization