title: [Bilateral nephrectomy in patients with end-stage renal failure and chronic active pyelonephritis].
abstract: This study analyzed the results of bilateral nephrectomy in 14 patients with end-stage renal disease (ESRD) and chronic active pyelonephritis. Seven patients had urosepsis, and 10 patients had a purulent form of pyelonephritis, which was one-sided in 7 of them. In the early postoperative period, on average, after 9.3 days, 9 patients died. Statistically significant risk factors for death were: chronic hemodialysis, long-term antibiotic therapy, and existing sepsis. Intraoperative complications and postoperative morbidity were not significantly associated with death. The study results imply the need of differentiated approach to bilateral nephrectomy in patients with ESRD and risk factors for fatal outcome. It must be performed on the strong indications since the intervention does not lead to eradication of sepsis. It is advisable to perform "preventive, sanation" bilateral nephrectomy in the "cold period" in patients at risk for developing urosepsis.
authors.affiliation: Department of Urology of City Hospital 52, Moscow HCD.
authors.forename: M A
authors.initials: MA
authors.lastname: Lysenko
authors.affiliation: Department of Urology of City Hospital 52, Moscow HCD.
authors.forename: V I
authors.initials: VI
authors.lastname: Vtorenko
authors.affiliation: Department of Urology of City Hospital 52, Moscow HCD.
authors.forename: R N
authors.initials: RN
authors.lastname: Trushkin
authors.affiliation: Department of Urology of City Hospital 52, Moscow HCD.
authors.forename: A E
authors.initials: AE
authors.lastname: Lubennikov
authors.affiliation: Department of Urology of City Hospital 52, Moscow HCD.
authors.forename: A M
authors.initials: AM
authors.lastname: Sysoev
authors.affiliation: Department of Urology of City Hospital 52, Moscow HCD.
authors.forename: A A
authors.initials: AA
authors.lastname: Sokolov
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000000981:diagnostic imaging / Q000401:mortality* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011704:Pyelonephritis / Q000150:complications / Q000000981:diagnostic imaging / Q000401:mortality* / Q000601:surgery*
keywords: active for pyelonephritis; bilateral nephrectomy; dialysis; end-stage chronic renal failure; urosepsis