title: [Condition of the immune status at patients with the serous and purulent pyelonephritis according].
abstract: OBJECTIVE
  Studying of a condition of the immune status on for standard treatment at an acute serous and purulent pyelonephritis.
  
  
  METHODS
  The immune status of 62 patients with various forms of an acute pyelonephritis, randomized on age, sex, the minimum quantity of associated diseases in a remission stage is surveyed.
  
  
  RESULTS
  and their discussion. Purulent form of acute pyelonephritis was accompanied by higher levels of pro-inflammatory cytokines with decreased levels of anti-inflammatory cytokines. In serous form, imbalance in the cytokine system was found. Both serous and purulent forms of pyelonephritis were characterized by the imbalance in the complement system, increased production of immunoglobulins with simultaneous reduction of circulating immune complexes, decreased activity and the intensity of phagocytosis with increased metabolic activity of neutrophils.
  
  
  CONCLUSIONS
  At serous and purulent forms of a pyelonephritis there are differences in an orientation and expression of changes of the immune indicators demanding development of methods of the differentiated immunorehabilitation.
authors.affiliation: Kursk State Medical University.
authors.forename: A I
authors.initials: AI
authors.lastname: Konoplya
authors.affiliation: Kursk State Medical University.
authors.forename: O I
authors.initials: OI
authors.lastname: Bratchikov
authors.affiliation: Kursk State Medical University.
authors.forename: I M
authors.initials: IM
authors.lastname: Kholimenko
authors.affiliation: Russian Medical Academy of Postgraduated Formation of the Russian Ministry of Health, Urological Center Scientific Clinical Center of Russian Railways.
authors.forename: M N
authors.initials: MN
authors.lastname: Shatokhin
authors.affiliation: Russian Medical Academy of Postgraduated Formation of the Russian Ministry of Health, Urological Center Scientific Clinical Center of Russian Railways.
authors.forename: A R
authors.initials: AR
authors.lastname: Dzharimok
authors.affiliation: Russian Medical Academy of Postgraduated Formation of the Russian Ministry of Health, Urological Center Scientific Clinical Center of Russian Railways.
authors.forename: M Yu
authors.initials: MY
authors.lastname: Mavrin
authors.affiliation: Kursk State Medical University.
authors.forename: A L
authors.initials: AL
authors.lastname: Loktionov
mesh_terms: D000328:Adult; D016207:Cytokines / Q000097:blood* / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D010587:Phagocytosis; D011704:Pyelonephritis / Q000097:blood* / Q000276:immunology* / Q000534:rehabilitation
chemical_list: D016207:Cytokines
keywords: acute serous pyelonephritis; immune status; purulent pyelonephritis