title: Obesity, Hepatic Steatosis, and Their Impact on Fat Infiltration of the Trunk Musculature Using Unenhanced Computed Tomography.
abstract: OBJECTIVE
  The aim of the study was to assess whether hepatic steatosis predicts muscle fat content independent of body mass index (BMI).
  
  
  METHODS
  Regions of interest were drawn over several trunk muscles and over the right lobe of the liver to obtain the computed tomography (CT) density in 100 subjects with unenhanced CT studies of the abdomen and pelvis. Univariate and multivariate linear regression were used to examine the associations between BMI and hepatic steatosis and between BMI and trunk muscle density.
  
  
  RESULTS
  Body mass index was associated with trunk muscle fat (P < 0.05) and hepatic steatosis (P < 0.05). Computed tomography density of the liver correlated with that of each trunk muscle (P < 0.05). After adjusting for age, sex, and BMI, hepatic steatosis was associated with increased trunk muscle fat content in the psoas only.
  
  
  CONCLUSIONS
  The association between muscle fat in most trunk muscles and hepatic steatosis is due to underlying BMI. However, hepatic steatosis predicted psoas muscle fat content independent of BMI (P < 0.05).
authors.affiliation: From the Department of Radiology, University of Pennsylvania, Philadelphia, PA.
authors.forename: Ronnie
authors.initials: R
authors.lastname: Sebro
mesh_terms: D050153:Abdominal Fat / Q000000981:diagnostic imaging*; D000009:Abdominal Muscles / Q000000981:diagnostic imaging; D000328:Adult; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005234:Fatty Liver / Q000150:complications* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*