title: Combined effectiveness of prior and current season influenza vaccination in northern Spain: 2016/17 mid-season analysis.
abstract: The 2016/17 mid-season vaccine effectiveness estimate against influenza A(H3N2) was 15% (95% confidence interval: -11 to 35) in Navarre. Comparing to individuals unvaccinated in the current and four prior seasons, effectiveness was 24% for current and 3-4 prior doses, 61% for current and 1-2 prior doses, 42% for only current vaccination, and 58% for 3-4 prior doses. This suggests moderate effectiveness for different combinations of vaccination in the current and prior seasons.
authors.affiliation: Instituto de Salud Pública de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.|CIBER Epidemiología y Salud Pública (CIBERESP), Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Castilla
authors.affiliation: Complejo Hospitalario de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Navascués
authors.affiliation: Instituto de Salud Pública de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.|CIBER Epidemiología y Salud Pública (CIBERESP), Spain.
authors.forename: Itziar
authors.initials: I
authors.lastname: Casado
authors.affiliation: Instituto de Salud Pública de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
authors.forename: Jorge
authors.initials: J
authors.lastname: Díaz-González
authors.affiliation: CIBER Epidemiología y Salud Pública (CIBERESP), Spain.|Complejo Hospitalario de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
authors.forename: Alejandra
authors.initials: A
authors.lastname: Pérez-García
authors.affiliation: Instituto de Salud Pública de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
authors.forename: Leticia
authors.initials: L
authors.lastname: Fernandino
authors.affiliation: Instituto de Salud Pública de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.|CIBER Epidemiología y Salud Pública (CIBERESP), Spain.
authors.forename: Iván
authors.initials: I
authors.lastname: Martínez-Baz
authors.affiliation: Complejo Hospitalario de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
authors.forename: Aitziber
authors.initials: A
authors.lastname: Aguinaga
authors.affiliation: Centro Nacional de Microbiología (WHO National Influenza Centre - Madrid), Instituto de Salud Carlos III, Majadahonda, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Pozo
authors.affiliation: Complejo Hospitalario de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Ezpeleta
authors.affiliation: The members of these networks are listed at the end of the article.
authors.lastname: Primary Health Care Sentinel Network And The Network For Influenza Surveillance In Hospitals Of Navarre
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology / Q000627:therapeutic use*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D012424:Rural Population; D012621:Seasons; D018571:Sentinel Surveillance; D013030:Spain / Q000453:epidemiology; D014505:Urban Population; D014611:Vaccination / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines
keywords: case control study; influenza; influenza vaccine; influenza-like illness; repeated vaccination; vaccine effectiveness