title: Predictive Behavior of a Computational Foot/Ankle Model through Artificial Neural Networks.
abstract: Computational models are useful tools to study the biomechanics of human joints. Their predictive performance is heavily dependent on bony anatomy and soft tissue properties. Imaging data provides anatomical requirements while approximate tissue properties are implemented from literature data, when available. We sought to improve the predictive capability of a computational foot/ankle model by optimizing its ligament stiffness inputs using feedforward and radial basis function neural networks. While the former demonstrated better performance than the latter per mean square error, both networks provided reasonable stiffness predictions for implementation into the computational model.
authors.affiliation: Department of Biomedical Engineering, Virginia Commonwealth University, 401 West Main Street, P.O. Box 843067, Richmond, VA 23284-3067, USA.
authors.forename: Ruchi D
authors.identifier: 0000-0003-2176-6390
authors.initials: RD
authors.lastname: Chande
authors.affiliation: Department of Electrical Engineering, Virginia Commonwealth University, 601 West Main Street, P.O. Box 843072, Richmond, VA 23284-3072, USA.
authors.forename: Rosalyn Hobson
authors.initials: RH
authors.lastname: Hargraves
authors.affiliation: Department of Mathematics & Applied Mathematics, Virginia Commonwealth University, 1015 Floyd Avenue, P.O. Box 842014, Richmond, VA 23284-2014, USA.
authors.forename: Norma
authors.identifier: 0000-0002-6072-2019
authors.initials: N
authors.lastname: Ortiz-Robinson
authors.affiliation: Department of Biomedical Engineering, Virginia Commonwealth University, 401 West Main Street, P.O. Box 843067, Richmond, VA 23284-3067, USA.
authors.forename: Jennifer S
authors.identifier: 0000-0001-7301-1008
authors.initials: JS
authors.lastname: Wayne
mesh_terms: D000465:Algorithms; D000843:Ankle Joint / Q000033:anatomy & histology*; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D005528:Foot / Q000033:anatomy & histology*; D006801:Humans; D008022:Ligaments / Q000033:anatomy & histology*; D008953:Models, Anatomic; D016571:Neural Networks, Computer; D009474:Neurons / Q000473:pathology; D016011:Normal Distribution