title: MicroRNAs in model and complex organisms.
abstract: Non-coding RNAs such as microRNAs (miRNAs) are very tiny ribonucleotides having an essential role in gene regulation at both post-transcriptional and translational levels. They are very conserved and expressed in worms, flies, plants, and mammals in a sequence-specific manner. Furthermore, it is now possible to clone miRNAs using the new genome editing tool CRISPR/cas9, which shows benefit in control of untargeted effect. In this special issue, we tried to cover researches associated with functional roles of miRNAs accross model and complex organisms.
authors.affiliation: Cereal Genomics Lab, Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, MT, USA. hikmet.budak@montana.edu.
authors.forename: Hikmet
authors.initials: H
authors.lastname: Budak
authors.affiliation: Department of Biology, East Carolina University, Greenville, NC, 27858, USA.
authors.forename: Baohong
authors.initials: B
authors.lastname: Zhang
mesh_terms: D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D008957:Models, Genetic; D010944:Plants / Q000235:genetics
chemical_list: D035683:MicroRNAs
keywords: CRISPR/Cas; Noncoding RNAs; Plant and human genome; miRNAs