title: Plasma Potassium Levels in Healthy Prehypertension Subjects and the Role of A High Potassium Drink.
abstract: Most populations around the world consume less than the recommended levels of potassium. Long term low potassium intake could lead to decreased plasma potassium levels and induce hypokalemia. The increasing of plasma potassium levels 0,2-0,4 mmol/L by improving potassium intake decreased significantly blood pressure (BP). Assessing plasma potassium levels in healthy people related to potassium intake have not been studied.
  
  
  
  In this study, we analysed plasma potassium levels in prehypertension (PHT) subjects to evaluate the effect of tender coconut water (TCW) as a high potassium drink on plasma potassium levels in PHT adults.
  
  
  
  Thirthy-two female aged 25-44 years were randomly allocated to 14 days on TCW or water in a parallel randomized clinical trial. The treatment (T) group received TCW 300 ml twice daily and the control (C) group received water 300 ml twice daily too.
  
  
  
  At baseline, plasma potassium levels was 3.71±0.41 mmol/L, and 22.58% were categorized as hypokalemia. After 14 days treatment, potassium plasma level between T and C groups were not significantly different (p=0,247). The change of plasma potassium levels in both groups showed tendency to increase but not statistically significant difference was observed (p=0.166).
  
  
  
  In healthy prehypertension women, the low levels of potassium plasma may be caused by low potassium intake for long time and intervension with TCW 300 ml twice daily for 14 consecutive days has not proven yet to increase plasma potassium levels. It is necessary to give higher dose and longer time to increase potassium plasma in low potassium plasma level subjects.
authors.affiliation: Department of Nutrition, Faculty of Public Health, Universitas Airlangga, P.O. Box: 60115, Surabaya, Indonesia.
authors.lastname: Farapti
authors.affiliation: Department of Clinical Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
authors.forename: Savitri
authors.initials: S
authors.lastname: Sayogo
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
authors.forename: Parlindungan
authors.initials: P
authors.lastname: Siregar
mesh_terms: D000328:Adult; D001628:Beverages; D001794:Blood Pressure / Q000502:physiology; D003059:Cocos; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000209:etiology; D011188:Potassium / Q000008:administration & dosage* / Q000097:blood*; D058246:Prehypertension / Q000097:blood*; D014867:Water / Q000008:administration & dosage
chemical_list: D014867:Water; D011188:Potassium
keywords: Plasma potassium levels; blood pressure; hypokalemia; potassium intake; prehypertension; tender coconut water