title: Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia.
abstract: A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service. We describe the history of clozapine trials and associated episodes of agranulocytosis and neutropenia, followed by the successfully tolerated third clozapine re-challenge within our service.
  
  
  BACKGROUND
  None.
  © The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.
authors.affiliation: , MB BCh, National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London, UK.
authors.forename: Jessica
authors.initials: J
authors.lastname: Foster
authors.affiliation: , MB MSc MRCPsych, South London and Maudsley NHS Foundation Trust, London, UK; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK; National Psychosis Unit, Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland.
authors.forename: John
authors.initials: J
authors.lastname: Lally
authors.affiliation: , BSc PhD DClinPsy, National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London, UK.
authors.forename: Victoria
authors.initials: V
authors.lastname: Bell
authors.affiliation: , BSc MBBS SFHEA PhD FRCPsych, National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London, UK; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.
authors.forename: Sukhi
authors.initials: S
authors.lastname: Shergill