title: Epidemiology and resistance pattern of bacterial isolates among cancer patients in a Tertiary Care Oncology Centre in North India.
abstract: OBJECTIVE
  To examine the epidemiology of microbiologically documented bacterial infection and the resistance pattern, among cancer patients undergoing treatment at RGCIRC, Delhi.
  
  
  METHODS
  Retrospective observational study in which culture reports obtained over 1 year in 2013, were analyzed.
  
  
  RESULTS
  13329 cultures were obtained over 1 year in 2013 and were analyzed. 23.6 % samples showed positive culture with majority being gram negative isolates (67.9 %). E. coli was the commonest gram negative isolate (49.4%) followed by klebsella (29.7%) and Staph. aureus was the commonest gram positive isolate. There was high incidence of ESBL in blood and urine (87.2% & 88.5%) and BLBLI were also high (78% & 83.9%). Carbapenem resistance was comparatively low (10%) and colistin sensitivity was quiet high (> 95%).
  
  
  CONCLUSIONS
  Prevalence of MRSA and VRE in our institute is very less, whereas prevalence of ESBLs and BLBLI isolates amongst gram negative infections is around 80%. Gram negative isolates had poor sensitivity to cephalosporins and fluoroquinolones.
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: U
authors.initials: U
authors.lastname: Batra
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: P
authors.initials: P
authors.lastname: Goyal
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: P
authors.initials: P
authors.lastname: Jain
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: A
authors.initials: A
authors.lastname: Upadhyay
authors.affiliation: Department of Lab Medicine, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: N
authors.initials: N
authors.lastname: Sachdeva
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: M
authors.initials: M
authors.lastname: Agarwal
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: D
authors.initials: D
authors.lastname: Bhurani
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: V
authors.initials: V
authors.lastname: Talwar
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Gupta
authors.affiliation: Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
authors.forename: D C
authors.initials: DC
authors.lastname: Doval
mesh_terms: D001424:Bacterial Infections / Q000097:blood / Q000453:epidemiology* / Q000382:microbiology* / Q000652:urine; D024881:Drug Resistance, Bacterial; D006801:Humans; D007194:India / Q000453:epidemiology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification; D009369:Neoplasms / Q000097:blood / Q000453:epidemiology* / Q000382:microbiology* / Q000652:urine; D015995:Prevalence; D012189:Retrospective Studies; D063128:Tertiary Health Care / Q000706:statistics & numerical data*; D065507:Vancomycin-Resistant Enterococci / Q000187:drug effects / Q000302:isolation & purification