title: [Effects of father's age on fertility, results of ART and health of children].
abstract: Many studies exist on the impact of female age on fertility, success of assisted reproductive technologies and on obstetric, fetal and neonatal adverse outcomes. Late paternity seems commonplace especially in the media… But there are reliable scientific data which confirm decline of fertility related to male age but also an increased risk of genetic diseases for the offspring. The objective of this article is to make a synthesis of the literature on this subject.
authors.affiliation: Laboratoire de biologie de la reproduction, CHI de Poissy-Saint-Germain-en-Laye, 78303 Poissy, France; EA 7404 GIG, faculté des sciences de la santé Simone-Veil, 78180 Montigny-Le-Bretonneux, France.
authors.forename: F
authors.initials: F
authors.lastname: Boitrelle
authors.affiliation: Service de gynécologie endocrinienne et médecine de la reproduction, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Plouvier
authors.affiliation: Service de gynécologie endocrinienne et médecine de la reproduction, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Dumont
authors.affiliation: Service de biologie de la reproduction-histologie-embryologie, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France; EA 4308 gamétogenèse et qualité du gamète, institut de biologie de la reproduction-spermiologie-CECOS, hôpital Albert-Calmette, centre hospitalier régional universitaire, 59000 Lille, France.
authors.forename: A-L
authors.initials: AL
authors.lastname: Barbotin
authors.affiliation: EA 4308 gamétogenèse et qualité du gamète, institut de biologie de la reproduction-spermiologie-CECOS, hôpital Albert-Calmette, centre hospitalier régional universitaire, 59000 Lille, France; Service d'andrologie, hôpital Albert-Calmette, CHRU de Lille, boulevard Jules-Leclercq, 59037 Lille cedex, France.
authors.forename: J-M
authors.initials: JM
authors.lastname: Rigot
authors.affiliation: Service de gynécologie-obstétrique et assistance médicale à la procréation, centre hospitalier des Quatre-Villes, rue Lauer, 92210 Saint-Cloud, France.
authors.forename: J
authors.initials: J
authors.lastname: Belaïsch-Allart
authors.affiliation: Service de gynécologie endocrinienne et médecine de la reproduction, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France; EA 4308 gamétogenèse et qualité du gamète, institut de biologie de la reproduction-spermiologie-CECOS, hôpital Albert-Calmette, centre hospitalier régional universitaire, 59000 Lille, France; Service d'andrologie, hôpital Albert-Calmette, CHRU de Lille, boulevard Jules-Leclercq, 59037 Lille cedex, France. Electronic address: geoffroy.robin@chru-lille.fr.
authors.forename: G
authors.initials: G
authors.lastname: Robin
mesh_terms: D000328:Adult; D005260:Female; D005298:Fertility / Q000502:physiology*; D005333:Fetus / Q000502:physiology; D030342:Genetic Diseases, Inborn / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010331:Paternal Age; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted; D012307:Risk Factors; D016896:Treatment Outcome
keywords: AMP; ART; De novo mutations; Fertility; Fertilité spontanée; Genetic diseases; Male age; Mutations de novo; Pathologies génétiques; Âge masculin