title: Is malignant otitis externa on the increase? A retrospective review of cases.
abstract: We performed a retrospective review of all patients with malignant otitis externa (MOE) treated in our center between July 2004 and December 2012 to evaluate the current epidemiology in our region and to ascertain causative factors associated with the perceived increase in the number of cases diagnosed. Eleven patients were identified (5 men and 6 women), with a mean age of 77 years (range: 38 to 97 years). Diabetes was present in 36%. Pseudomonas aeruginosa was the causative organism in 64% of cases; all pathogens were sensitive to ciprofloxacin. We noted a significant increase in the diagnostic frequency of MOE during the study period (p = 0.0027) No obvious causative factors were identified. Due to the mortality associated with this condition, further studies are required to establish national trends.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, York Teaching Hospital, NHS Foundation Trust, York, North Yorkshire, U.K. diana-bhasker@doctors.org.uk.
authors.forename: Diana
authors.initials: D
authors.lastname: Bhasker
authors.forename: Angela
authors.initials: A
authors.lastname: Hartley
authors.forename: Frank
authors.initials: F
authors.lastname: Agada
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010032:Otitis Externa / Q000188:drug therapy / Q000382:microbiology* / Q000401:mortality; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology* / Q000401:mortality; D011550:Pseudomonas aeruginosa; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin