title: Invasive pulmonary aspergillosis in an immunocompromised patient with severe ulcerative colitis.
abstract: Inflammatory bowel disease patients at risk of opportunistic infections are those treated with immunomodulators. Toruner and colleagues found that corticosteroid use was more commonly associated with fungal infections. We present a case of invasive pulmonary Aspergillosis due to corticosteroid therapy in the context of a severe Ulcerative Colitis flare. We want to highlight the relationship between Aspergillus fumigatus and horses; and the use of leucocitapheresis combined with mesalazine as an effective treatment option in this patients who can not take more immunosuppressive therapy.
authors.affiliation: Aparato Digestivo, Hospital Clínico Universitario Valencia, España.
authors.forename: David
authors.initials: D
authors.lastname: Marti Aguado
authors.affiliation: Aparato Digestivo, Hospital Clínico Universitario Valencia.
authors.forename: María Pilar
authors.initials: MP
authors.lastname: Ballester
authors.affiliation: Aparato Digestivo, Hospital Clínico Universitario Valencia.
authors.forename: Marta Maia
authors.initials: MM
authors.lastname: Bosca Watts
mesh_terms: D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D055744:Invasive Pulmonary Aspergillosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy*; D019804:Mesalamine / Q000009:adverse effects / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D019804:Mesalamine