title: Determinants of Malaria Transmission at the Population Level.
abstract: Transmission of malaria from man to mosquito defines the human infectious reservoir of malaria. At the population level this is influenced by a variety of human, parasite, and mosquito vector factors some or all of which may vary depending on the epidemiological setting. Here, we review our current state of knowledge related to human infectiousness to mosquitoes and how current malaria control strategies might be adapted to focus on reducing this. While much progress has been made in malaria control, we argue that an improved understanding of human infectivity will allow more effective use of current control tools and make elimination a more feasible goal.
authors.affiliation: Department of Medical Microbiology, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.|Department of Immunology & Infection, London School of Hygiene & Tropical Medicine, London WC1E 7HT, United Kingdom.
authors.forename: Teun
authors.initials: T
authors.lastname: Bousema
authors.affiliation: Department of Immunology & Infection, London School of Hygiene & Tropical Medicine, London WC1E 7HT, United Kingdom.
authors.forename: Chris
authors.initials: C
authors.lastname: Drakeley
mesh_terms: D000818:Animals; D009033:Culicidae / Q000469:parasitology*; D006801:Humans; D007303:Insect Vectors; D008288:Malaria / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission*