title: [Application of microelectronics CAD tools to synthetic biology].
abstract: Synthetic biology is an emerging science that aims to create new biological functions that do not exist in nature, based on the knowledge acquired in life science over the last century. Since the beginning of this century, several projects in synthetic biology have emerged. The complexity of the developed artificial bio-functions is relatively low so that empirical design methods could be used for the design process. Nevertheless, with the increasing complexity of biological circuits, this is no longer the case and a large number of computer aided design softwares have been developed in the past few years. These tools include languages for the behavioral description and the mathematical modelling of biological systems, simulators at different levels of abstraction, libraries of biological devices and circuit design automation algorithms. All of these tools already exist in other fields of engineering sciences, particularly in microelectronics. This is the approach that is put forward in this paper.
authors.affiliation: Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), 300, boulevard Sébastien Brandt, 67412 Illkirch, France.
authors.forename: Morgan
authors.initials: M
authors.lastname: Madec
authors.affiliation: Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), 300, boulevard Sébastien Brandt, 67412 Illkirch, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Haiech
authors.affiliation: Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), 300, boulevard Sébastien Brandt, 67412 Illkirch, France.
authors.forename: Élise
authors.initials: É
authors.lastname: Rosati
authors.affiliation: Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), 300, boulevard Sébastien Brandt, 67412 Illkirch, France.
authors.forename: Abir
authors.initials: A
authors.lastname: Rezgui
authors.affiliation: Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), 300, boulevard Sébastien Brandt, 67412 Illkirch, France.
authors.forename: Yves
authors.initials: Y
authors.lastname: Gendrault
authors.affiliation: Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), 300, boulevard Sébastien Brandt, 67412 Illkirch, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Lallement
mesh_terms: D000465:Algorithms; D000818:Animals; D017076:Computer-Aided Design / Q000639:trends; D004582:Electronics, Medical / Q000295:instrumentation / Q000379:methods; D006801:Humans; D055616:Microtechnology / Q000295:instrumentation / Q000379:methods; D012984:Software; D058615:Synthetic Biology / Q000379:methods*; D049490:Systems Biology / Q000379:methods