title: Relapsing Polychondritis Presented with Encephalitis Followed by Brain Atrophy.
abstract: Relapsing polychondritis (RP) is a rare autoimmune disease that is characterized by inflammatory reaction of unknown etiology and destruction of cartilaginous structures. Characteristic symptoms of this disease include cartilage inflammation of the ear, nose, larynx, trachea, bronchi, joints, eyes, heart and skin. Concomitance with neurologic symptom is very rare in RP, and the detailed underlying mechanism of neurological involvement associated with RP is not fully understood. We herein described an unusual recurrent case of inflammatory brain lesions associated with RP, with attention to clinical manifestations, autoimmune disease involvement, and therapeutic effects.
authors.affiliation: Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
authors.forename: Suk-Won
authors.initials: SW
authors.lastname: Ahn
authors.affiliation: Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
authors.forename: Moo-Seok
authors.initials: MS
authors.lastname: Park
authors.affiliation: Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
authors.forename: Hae-Bong
authors.initials: HB
authors.lastname: Jeong
authors.affiliation: Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
authors.forename: Oh-Sang
authors.initials: OS
authors.lastname: Kwon
authors.affiliation: Department of Neurology, Inha University Hospital, Inha University College of Medicine, Incheon 22332, Korea.
authors.forename: Byung-Nam
authors.initials: BN
authors.lastname: Yoon
authors.affiliation: Department of Pathology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
authors.forename: Hee Sung
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Department of Rheumatology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06974, Korea.
authors.forename: Sang Tae
authors.initials: ST
authors.lastname: Choi
keywords: Brain atrophy; Encephalitis; Multiple sclerosis; Neuromyelitis optica; Relapsing polychondritis