title: The predictors of poor quality of life in a sample of Saudi women with breast cancer.
abstract: BACKGROUND
  The protocols for treatment, along with many adverse effects, can strongly affect cancer patients' quality of life (QoL). As there is limited research on the QoL of Saudi Arabian women being treated for breast cancer, the purpose of this study was to identify the predictors of poor QoL in a sample of Saudi women with breast cancer.
  
  
  METHODS
  A cross-sectional study was conducted on 145 Saudi women with breast cancer who attended the Oncology Outpatient Clinic at King Abdulaziz Medical City, Riyadh for routine follow-up. Sociodemographic and clinical data were collected for each patient, and a Medical Outcome Study Health Survey 36-Item Short Form (SF-36) instrument was used to assess QoL.
  
  
  RESULTS
  Of 145 breast cancer patients studied, 42.1% had a family history of cancer and 52.4% were newly diagnosed cancer patients (first-year-after-cancer diagnosis). According to linear regression analyses, cancer patients with metastasis tended to have pain, along with poor physical function, little vitality, and poor general health (a decrease in SF-36 scores of 22.9, 15.0, 19.4, and 16.9, respectively). Regular exercise was a positive predictor of poor general health (an increase in the SF-36 score of 8.2). Patients with first-year-after-cancer diagnoses tended to have poor emotional well-being (a decrease in the SF-36 score of 8.5).
  
  
  CONCLUSIONS
  In breast cancer patients, regular exercise was a significant positive predictor of better general health. Breast cancer patients with multiple tumors, metastasis, or fever tended to experience significantly poor QoL in several SF-36 domains. Clearly, a routine assessment of QoL in breast cancer patients is important.
authors.affiliation: King Abdullah International Medical Research Center (KAIMRC); College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences.
authors.forename: Anwar E
authors.initials: AE
authors.lastname: Ahmed
authors.affiliation: College of Medicine, Imam Abdulrahman Al Faisal University, Dammam.
authors.forename: Abdulrahman G
authors.initials: AG
authors.lastname: Alharbi
authors.affiliation: College of Medicine, King Saud University.
authors.forename: Mohannad A
authors.initials: MA
authors.lastname: Alsadhan
authors.affiliation: College of Medicine, King Saud bin Abdulaziz University for Health Sciences.
authors.forename: Alaa S
authors.initials: AS
authors.lastname: Almuzaini
authors.affiliation: College of Medicine, King Saud bin Abdulaziz University for Health Sciences.
authors.forename: Hanin S
authors.initials: HS
authors.lastname: Almuzaini
authors.affiliation: Department of Oncology, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
authors.forename: Yosra Z
authors.initials: YZ
authors.lastname: Ali
authors.affiliation: Department of Oncology, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
authors.forename: Abdul-Rahman
authors.initials: AR
authors.lastname: Jazieh
keywords: SF-36; fever; metastasis; multiple tumors; regular exercise