title: [Bilateral ciliary body oedema under treatment with ciclosporine].
abstract: We present the case of a 27-year-old female patient who developed bilateral ciliary body edema with secondary glaucoma and myopic shift during systemic treatment with cyclosporine for aplastic anemia. After application of topical atropine and prednisolone acetate and conversion from cyclosporine to tacrolimus, the ophthalmologic symptoms resolved completely. Since an infectious etiology was not evident, we hypothesize that ciliary body edema was caused by impairment of microvascular integrity by cyclosporine.
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland. regine.braun@ukr.de.
authors.forename: R
authors.initials: R
authors.lastname: Braun
authors.affiliation: Klinik und Poliklinik für Innere Medizin III, Universitätsklinikum Regensburg, Regensburg, Deutschland.
authors.forename: E
authors.initials: E
authors.lastname: Holler
authors.affiliation: Klinik und Poliklinik für Innere Medizin III, Universitätsklinikum Regensburg, Regensburg, Deutschland.
authors.forename: D
authors.initials: D
authors.lastname: Wolff
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Helbig
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Blecha
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.|Klinik für Augenheilkunde, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Dietrich-Ntoukas
mesh_terms: D000328:Adult; D001285:Atropine; D002924:Ciliary Body; D016572:Cyclosporine / Q000627:therapeutic use*; D004487:Edema / Q000188:drug therapy*; D005260:Female; D015812:Glaucoma, Angle-Closure; D006801:Humans; D009216:Myopia
chemical_list: D001285:Atropine; D016572:Cyclosporine
keywords: Aplastic anemia; Bilateral angle closure glaucoma; Secondary glaucoma; Tacrolimus; Transient myopia