title: Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles.
abstract: Disubstituted hydroxylamines were synthesized and used to form aluminum-amide complexes. These reagents masked carbonyl groups in situ from nucleophilic addition. The stability and utility of the aluminum-aminals are presented in the context of selectively controlling nucleophilic addition on substrates with multiple carbonyl groups.
authors.affiliation: Department of Chemistry and Physics, Bellarmine University, 2001 Newburg Rd., Louisville, Kentucky 40205.
authors.forename: Francis J
authors.initials: FJ
authors.lastname: Barrios
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907.
authors.forename: Brannon C
authors.initials: BC
authors.lastname: Springer
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907; Department of BioMolecular Sciences, University of Mississippi, 317 Faser Hall, P. O. Box 1848, University, Mississippi 38677.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Hazlitt
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907; Department of BioMolecular Sciences, University of Mississippi, 317 Faser Hall, P. O. Box 1848, University, Mississippi 38677.
authors.forename: David A
authors.initials: DA
authors.lastname: Colby
keywords: aluminum; amides; amines; carbonyl complexes; nucleophilic addition