title: Multiple Skin Colored Nodules on both Legs in Patient with Positive QuantiFERON®-TB Gold Test.
abstract: Nodular tuberculid (NT) was originally described by Jordaan et al. in 2000 in 4 patients from South Africa. It appeared as nodules on the legs; the pathologic changes were situated in the deep dermis and adjacent subcutaneous fat. A 34-year-old woman visited our hospital with subcutaneous skin-colored or slightly erythematous round to oval nodules. Skin biopsies revealed granulomatous inflammation at the dermo-subcutaneous junction with vasculitis. Chest X-ray, tuberculosus (TB)-polymerase chain reaction and TB culture of the skin specimen were normal. A QuantiFERON®-TB Gold test (QUIAGEN, Germany) was positive, which suggested a diagnosis of latent TB infection. The patient was treated with anti-TB medication and her condition has not recurred. Herein, we report a case of a patient with latent TB diagnosed by a positive QuantiFERON®-TB Gold test whose skin lesions had the clinical and histopathologic features of NT.
authors.affiliation: Department of Dermatology, Dankook University Medical College, Cheonan, Korea.
authors.forename: Mi Soo
authors.initials: MS
authors.lastname: Choi
authors.affiliation: Department of Dermatology, Dankook University Medical College, Cheonan, Korea.
authors.forename: Seung Phil
authors.initials: SP
authors.lastname: Hong
authors.affiliation: Department of Dermatology, Dankook University Medical College, Cheonan, Korea.
authors.forename: Byung Cheol
authors.initials: BC
authors.lastname: Park
authors.affiliation: Department of Dermatology, Dankook University Medical College, Cheonan, Korea.
authors.forename: Myung Hwa
authors.initials: MH
authors.lastname: Kim
keywords: Nodular tuberculid; QuantiFERON®-TB Gold test; Tuberculid