title: [Chronic skin ulcer in a 24-year-old man after a journey to Southeast Asia].
abstract: Our report concerns a 24-year-old man with a chronic exsudative skin lesion after a journey to Southeast Asia. The diagnosis of melioidosis was made by the identification of Burkholderia pseudomallei from the ichor. The diagnosis was confirmed by polymerase change reaction. The patient was treated with meropenem i. v. for about 10 days and with trimethoprim/sulfamethoxazole for the following 12 weeks. Melioidosis is an endemic disease in Southeast Asia and North Australia which in some cases can run a severe course and can have a high fatality rate. The relevance of melioidosis becomes more important against the background of the increasing global movement of travelers and migration.
authors.affiliation: Medizinische Klinik II, Klinikum am Steinenberg, Steinenbergstr. 31, 72764, Reutlingen, Deutschland. rueda_a@klin-rt.de.
authors.forename: A
authors.initials: A
authors.lastname: Rueda Guzmán
authors.affiliation: Tropenklinik Paul-Lechler-Krankenhaus, Tübingen, Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Slesak
authors.affiliation: Tropenklinik Paul-Lechler-Krankenhaus, Tübingen, Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Fleck
authors.affiliation: Labor Enders und Partner, Stuttgart, Deutschland.|Institut für Mikrobiologie und Hygiene, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Ignatius
authors.affiliation: Landesgesundheitsamt im Regierungspräsidium, Stuttgart, Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Oehme
authors.affiliation: Tropenklinik Paul-Lechler-Krankenhaus, Tübingen, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Schäfer
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001210:Asia, Southeastern; D016957:Burkholderia pseudomallei / Q000302:isolation & purification*; D002908:Chronic Disease; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000175:diagnosis* / Q000188:drug therapy; D000077731:Meropenem; D012883:Skin Ulcer / Q000188:drug therapy / Q000382:microbiology*; D013845:Thienamycins / Q000627:therapeutic use; D000076082:Travel-Related Illness; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; D000077731:Meropenem
keywords: Burkholderia pseudomallei; Melioidosis; Meropenem; Pneumonia; Trimethoprim, sulfamethoxazole drug combination