title: [Quantitative mineralogical analysis and structure of urinary stones in patients living in Ivanovo region].
abstract: This paper focuses on developing and implementing a method of quantitative mineralogical analysis of urinary stones based on powder diffraction data analysis using 4 Topas (Bruker) software. Mineralogical composition of 100 urinary stones from urolithiasis patients living in Ivanovo region was examined. More than 70% of stones consisted of calcium oxalate monohydrate (COM) and calcium oxalate dihydrate (COD), and their mixtures with hydroxylapatite. Forty four percent of urinary stones consisted of one component (COM, uric acid (UA) or, less frequently, hydroxyapatite (HA); 56% of urinary stones comprised two, three or four components. The most common mineral was COM (more than 70% of cases), the rarest were calcium oxalate trihydrate (CT), brushite and newberrite. The most common combinations of minerals in mixed stones were COM+HA, COM+COD and COM+COD+HA. The texture, the surface composition and its changes in the course of chemolysis in different types of stones were examined using scanning electron microscopy (SEM) and X-ray microanalysis (XRM). Implications for using analytical chemical and physical techniques for the diagnosis and treatment of urolithiasis were discussed.
authors.affiliation: G. A. Krestov Institute of Solution Chemistry of the RAS.|Department of Surgery and Urology Ivanovo State Medical University.
authors.forename: A V
authors.initials: AV
authors.lastname: Kustov
authors.affiliation: Department of Surgery and Urology Ivanovo State Medical University.
authors.forename: A I
authors.initials: AI
authors.lastname: Strelnikov
authors.affiliation: G. A. Krestov Institute of Solution Chemistry of the RAS.
authors.forename: P R
authors.initials: PR
authors.lastname: Smirnov
authors.affiliation: Department of Solid State Physics, Belarusian State University, Minsk.
authors.forename: S V
authors.initials: SV
authors.lastname: Gusakova
authors.affiliation: Ivanovo Regional Clinical Hospital.
authors.forename: M A
authors.initials: MA
authors.lastname: Moryganov
authors.affiliation: Department of Surgery and Urology Ivanovo State Medical University.|Ivanovo Regional Clinical Hospital.
authors.forename: S R
authors.initials: SR
authors.lastname: Toms
authors.affiliation: Ivanovo Regional Clinical Hospital.
authors.forename: S I
authors.initials: SI
authors.lastname: Gruzdev
authors.affiliation: Department of Surgery and Urology Ivanovo State Medical University.
authors.forename: A O
authors.initials: AO
authors.lastname: Airapetyan
mesh_terms: D002129:Calcium Oxalate / Q000378:metabolism*; D002130:Calcium Phosphates / Q000378:metabolism*; D017886:Durapatite / Q000378:metabolism*; D005260:Female; D006801:Humans; D017616:Magnesium Compounds / Q000378:metabolism*; D008297:Male; D010710:Phosphates / Q000378:metabolism*; D012426:Russia / Q000453:epidemiology; D014527:Uric Acid / Q000378:metabolism*; D014545:Urinary Calculi / Q000453:epidemiology / Q000378:metabolism*
chemical_list: D002130:Calcium Phosphates; D017616:Magnesium Compounds; D010710:Phosphates; D002129:Calcium Oxalate; D014527:Uric Acid; C030781:magnesium phosphate; D017886:Durapatite; C494366:calcium phosphate, dibasic, dihydrate
keywords: X-ray microanalysis; electron microscopy; powder diffraction analysis; quantitative mineralogical analysis; urolithiasis