title: Prevalence of Hypertrophic Cardiomyopathy in Fetuses of Mothers with Gestational Diabetes before Initiating Treatment.
abstract: ObjectiveTo evaluate the prevalence of hypertrophic cardiomyopathy (HCM) in fetuses of pregnant women with gestational diabetes mellitus (GDM) in the beginning of the treatment.MethodsA cross-sectional study was performed between July 1, 2013, and December 20, 2013, in a public maternity clinic in southern Brazil. The subjects were 63 fetuses of mothers with gestational diabetes, with a single pregnancy and no other associated pathologies. We diagnosed HCM through a fetal echocardiography before treatment and evaluated the maternal and fetal characteristics.ResultsThe average age of the pregnant women was 32.32 (±6.2) years, and the average gestational age at the time of the evaluation was 30.59 (±2.27) weeks. The interventricular septum thickness showed a standard deviation of more than two in 50.8% of the fetuses (95% confidence interval [95%CI]: 38.1-63.5%). The left ventricular wall thickness showed a standard deviation of more than 2 in 13 (20.6%) fetuses (95%CI: 11.1-30.2%). The HCM was confirmed in 54% of the fetuses (95%CI: 41.3-65.1%). The fetal abdominal circumference was normal in 46 (73%) fetuses, and 50% of these fetuses had HCM.ConclusionThe prevalence of hypertrophic cardiomyopathy in fetuses of pregnant women with GDM before treatment was of 54% (95%CI: 41.3-65.1%).
authors.affiliation: Health and Environment Master Program, Universidade da Região de Joinville (Univille), Joinville, Santa Catarina, Brazil.
authors.forename: Carolina Rossi
authors.initials: CR
authors.lastname: Palmieri
authors.affiliation: Department of Neonatology, Maternidade Darcy Vargas, Joinville, Santa Catarina, Brazil.
authors.forename: Mona Adalgisa
authors.initials: MA
authors.lastname: Simões
authors.affiliation: Department of Medicine, Universidade da Região de Joinville (Univille), Joinville, Santa Catarina, Brazil.
authors.forename: Jean Carl
authors.initials: JC
authors.lastname: Silva
authors.affiliation: Universidade da Região de Joinville (Univille), Joinville, Santa Catarina, Brazil.
authors.forename: Anelise Darabas Dos
authors.initials: AD
authors.lastname: Santos
authors.affiliation: Universidade da Região de Joinville (Univille), Joinville, Santa Catarina, Brazil.
authors.forename: Mariana Ribeiro E
authors.initials: MR
authors.lastname: Silva
authors.affiliation: Universidade da Região de Joinville (Univille), Joinville, Santa Catarina, Brazil.
authors.forename: Bruna
authors.initials: B
authors.lastname: Ferreira
mesh_terms: D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D016640:Diabetes, Gestational / Q000628:therapy; D005260:Female; D005315:Fetal Diseases / Q000453:epidemiology*; D006801:Humans; D011247:Pregnancy; D015995:Prevalence