title: Recognition, diagnosis, and treatment of cognitive and psychiatric disorders in patients with COPD.
abstract: COPD is highly prevalent and associated with substantial morbidity and mortality. Clinicians have long been aware that patients with COPD have problems with cognition and are susceptible to mood (depression) and anxiety disorders. With the increasing awareness of COPD as a multisystem disorder, many studies have evaluated the prevalence of neuropsychiatric conditions in patients with COPD. This review presents evidence regarding the prevalence of neuropsychiatric conditions (cognitive disorders/impairment, depression/anxiety) in COPD, their risk factors, and their impact on relevant outcomes. It also discusses both assessment and treatment of neuropsychiatric conditions and makes recommendations for improved screening and treatment. The findings suggest that clinicians caring for patients with COPD must become familiar with diagnosing these comorbid conditions and that future treatment has the potential to impact these patients and thereby improve COPD outcomes.
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Henry Ford Hospital, Detroit, MI, USA.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Ouellette
authors.affiliation: Montreal Behavioral Medicine Center (MBMC), Research Center, Integrated University Health and Social Services Center - Sacred Heart Hospital of Montreal, Montreal, QC, Canada.
authors.forename: Kim L
authors.initials: KL
authors.lastname: Lavoie
mesh_terms: D000339:Affect; D001007:Anxiety / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D003071:Cognition; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D018450:Disease Progression; D006801:Humans; D008168:Lung / Q000503:physiopathology; D011237:Predictive Value of Tests; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D012307:Risk Factors; D016896:Treatment Outcome
keywords: COPD; anxiety disorders; cognitive impairment; hypoxemia; mood disorders; pulmonary rehabilitation