title: Update on CT and MRI of Adrenal Nodules.
abstract: OBJECTIVE
  The objective of this article is to review the current role of CT and MRI for the characterization of adrenal nodules.
  
  
  CONCLUSIONS
  Unenhanced CT and chemical-shift MRI have high specificity for lipid-rich adenomas. Dual-energy CT provides comparable to slightly lower sensitivity for the diagnosis of lipid-rich adenomas but may improve characterization of lipid-poor adenomas. Nonadenomas containing intracellular lipid pose an imaging challenge; however, nonadenomas that contain lipid may be potentially diagnosed using other imaging features. Multiphase adrenal washout CT can be used to differentiate lipid-poor adenomas from metastases but is limited for the diagnosis of hypervascular malignancies and pheochromocytoma.
authors.affiliation: 1 Department of Radiology, The Ottawa Hospital, The University of Ottawa, 1053 Carling Ave, Civic Campus C1, Ottawa, ON K1Y 4E9, Canada.
authors.forename: Nicola
authors.initials: N
authors.lastname: Schieda
authors.affiliation: 2 Department of Radiology, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA.
authors.forename: Evan S
authors.initials: ES
authors.lastname: Siegelman
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D019317:Evidence-Based Medicine; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D015588:Observer Variation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
keywords: CT; MRI; adenoma; adrenal; dual-energy CT