title: Gender based differences in drug eluting stent implantation - data from the German ALKK registry suggest underuse of DES in elderly women.
abstract: Observational studies suggest there are gender based differences in the treatment of coronary artery disease, with women receiving evidence based therapy less frequently than suggested by current guidelines. The aim of our study was to evaluate gender based differences in the use of DES.
  
  
  
  We analysed prospectively collected data from 100704 stent implantations in the PCI registry of the ALKK between 2005 and 2009.
  
  
  
  The usage of DES increased from 16.0 to 43.9%. Although women had smaller vessel sizes, they received DES less often compared to men (28.2 vs. 31.3%), with an adjusted odds ratio of 0.93 (95% confidence interval 0.89-0.97) at the age of 75, and an adjusted odds ratio of 0.89 (95% confidence interval 0.84-0.94) at the age of 80.
  
  
  
  Despite having smaller vessels than men, women were treated less often with DES. These findings apply to women above the age of 75 years. These findings support previous reports, that elderly women with coronary artery disease are treated differently to men.
authors.affiliation: Internistische Praxis am Maxplatz, Maxplatz 12, 83278, Traunstein, Germany. martin.russ@posteo.de.|Amper-Klinikum, Dachau, Krankenhausstrasse 15, 85221, Dachau, Germany. martin.russ@posteo.de.
authors.forename: Martin A
authors.initials: MA
authors.lastname: Russ
authors.affiliation: Amper-Klinikum, Dachau, Krankenhausstrasse 15, 85221, Dachau, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Wackerl
authors.affiliation: Institut für Herzinfarktforschung, Bremserstr, 79, 67063, Ludwigshafen, Germany.|Medizinische Klinik B - Abteilung für Kardiologie, Bremserstr. 79, 67063, Ludwigshafen, Germany.
authors.forename: Uwe
authors.initials: U
authors.lastname: Zeymer
authors.affiliation: Institut für Herzinfarktforschung, Bremserstr, 79, 67063, Ludwigshafen, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Hochadel
authors.affiliation: Herz- und Gefäß-Klinik GmbH Bad Neustadt, Salzburger Leite1, 97616, Bad Neustadt a.d. Saale, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Kerber
authors.affiliation: Medizinische Klinik B - Abteilung für Kardiologie, Bremserstr. 79, 67063, Ludwigshafen, Germany.
authors.forename: Ralf
authors.initials: R
authors.lastname: Zahn
authors.affiliation: Krankenhaus Landshut-Achdorf, Medizinische Klinik I, Achdorfer Weg 3, 84036, Landshut, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Zrenner
authors.affiliation: Sana-Klinikum Hameln-Pyrmont, Saint-Maur-Platz 1, 31785, Hameln, Germany.
authors.forename: Hubert
authors.initials: H
authors.lastname: Topp
authors.affiliation: Klinikum Fulda, Medizinische Klinik I, Pacelliallee 4, 36043, Fulda, Germany.
authors.forename: Volker
authors.initials: V
authors.lastname: Schächinger
authors.affiliation: Amper-Klinikum, Dachau, Krankenhausstrasse 15, 85221, Dachau, Germany.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Weber
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D054855:Drug-Eluting Stents; D005260:Female; D005858:Germany; D054625:Healthcare Disparities; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000295:instrumentation*; D017064:Process Assessment, Health Care; D011474:Prosthesis Design; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome
keywords: Drug eluting stents; Gender differences; PCI– registry