title: Antibacterial efficacy of several intracanal medicaments for endodontic therapy.
abstract: The antibacterial efficacy of intracanal medicaments for 2 and 7 days, in open apex root canals contaminated with Enterococcus faecalis biofilms was compared. One hundred and thirty-eight standardized uniradicular human roots were inoculated with E. faecalis. Colony forming units (CFU) were recorded before and after medication. Samples were divided in two (2/7 days), and subdivided (n=8/group): triple antibiotic paste (TAP); double antibiotic paste (DAP); dental base paste (DBP), consisting of calcium hydroxide, propylene glycol and calcium carbonate; DBP+0.2% chlorhexidine (CHX); DBP+0.2% cetrimide (CTR); DBP+0.2% CHX+0.2% CTR; 2.5% sodium hypochlorite (NaOCl); and distilled water. At both periods TAP, DAP, DBP+0.2% CHX, DBP+0.2% CTR and DBP+0.2% CHX+0.2% CTR exhibited no growth (NG) of E. faecalis. Distilled water and 2.5% NaOCl obtained the lowest CFU reduction. No growth with DBP was reached only at 7 days. CHX and/or CTR pastes were as effective as DAP and TAP. A 2-day period provided an effective disinfection.
authors.affiliation: Stomatology Area, Health Sciences Faculty, Rey Juan Carlos University.
authors.forename: Marta E
authors.initials: ME
authors.lastname: Valverde
authors.affiliation: Department of Stomatology, School of Dentistry, University of Granada.
authors.forename: Pilar
authors.initials: P
authors.lastname: Baca
authors.affiliation: Stomatology Area, Health Sciences Faculty, Rey Juan Carlos University.
authors.forename: Laura
authors.initials: L
authors.lastname: Ceballos
authors.affiliation: Stomatology Area, Health Sciences Faculty, Rey Juan Carlos University.
authors.forename: M Victoria
authors.initials: MV
authors.lastname: Fuentes
authors.affiliation: Department of Stomatology, School of Dentistry, University of Granada.
authors.forename: Matilde
authors.initials: M
authors.lastname: Ruiz-Linares
authors.affiliation: Department of Stomatology, School of Dentistry, University of Granada.
authors.forename: Carmen María
authors.initials: CM
authors.lastname: Ferrer-Luque
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000627:therapeutic use; D003786:Dental Pulp Cavity; D013293:Enterococcus faecalis; D006801:Humans; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D012973:Sodium Hypochlorite / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite; D002710:Chlorhexidine
keywords: Cetrimide; Chlorhexidine; Double antibiotic paste; Propylene glycol; Regenerative endodontic therapy