title: Dosimetry study of three-dimensional print template-guided precision125I seed implantation.
abstract: OBJECTIVE
  This study aimed to compare the dose difference in 125 I seed implantation between three-dimensional (3D) print template-guided operation and traditional implantation.
  
  
  METHODS
  This study retrospectively analyzed 27 patients who underwent 125I seed implantation from August 2015 to December 2015 in Hebei General Hospital. Of these, 13 underwent seed implantation guided by a 3D print template, named the template group, and 14 underwent traditional implantation, named the traditional group. All patients underwent computed tomography (CT) scan. Then, 3D templates were printed in the template group. The implantation was guided by CT and 3D templates. The patients in the traditional group underwent implantation with free hands guided by CT scan. Postplan was performed after the operation. The dose-volume histogram, D90, and V90 were calculated. The D90 values pre- and post-operation were compared in each group. The postoperation V90 values of the two groups were also compared.
  
  
  RESULTS
  The mean D90 values pre- and post-operation in the template group were (87.09 ± 33.63) Gy and (85.31 ± 34.40) Gy, respectively, with no statistically significant difference. The mean D90 values pre- and post-operation in the traditional group were (86.04 ± 29.93) Gy and (74.96 ± 46.10) Gy, respectively, with a statistically significant difference. The mean V90 values postoperation in the template and traditional groups were (92.76% ± 1.89%) and (84.59% ± 7.56%), respectively, with a statistically significant difference.
  
  
  CONCLUSIONS
  The postplan and preplan dose parameters of 3D print template-guided seed implantation were nearly consistent. The dose parameters of template group superior to the traditional group. The seeds can be implanted accurately with 3D print template.
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Zhang
authors.initials: Z
authors.lastname: Hongtao
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Di
authors.initials: D
authors.lastname: Xuemin
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Huimin
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Zeyang
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Zhang
authors.initials: Z
authors.lastname: Lijuan
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Jinxin
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Liu
authors.initials: L
authors.lastname: Zezhou
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Sui
authors.initials: S
authors.lastname: Aixia
authors.affiliation: Department of Oncology, The Hebei General Hospital, Shijiazhuang 050051, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Juan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000379:methods; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D019233:Retreatment; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes