title: [Metabolic syndrome as a cause of reduced ejaculate fertility in patients with prostatic tuberculosis].
abstract: BACKGROUND
  Metabolic syndrome (MS) negatively affects the quality of ejaculate, especially in patients with chronic prostatitis.
  
  
  METHODS
  To determine the effect of metabolic syndrome on semen parameters in patients with tuberculosis of the prostate (TP), a study of 72 patients with prostatic tuberculosis was conducted. MS was diagnosed when at least three of the five following medical conditions were found: central obesity, elevated levels of plasma triglycerides, high blood pressure, hyperglycemia and decreased levels of high-density lipoproteins. Semen parameters were compared in patients with tuberculosis of the prostate with and without MS.
  
  
  RESULTS
  41% of patients with prostatic tuberculosis had metabolic syndrome, which was associated with a 1.5, 1.4 and 2.5 fold decreases in the number of sperm, sperm concentration, and the number of normal sperm forms, respectively.
  
  
  CONCLUSIONS
  These findings provide the rationale for developing specific therapies aimed at restoring ejaculate fertility in patients with prostatic tuberculosis, considering that almost a half of them have MS.
authors.affiliation: Novosibirsk Tuberculosis Research Institute of Minzdrav of Russia.|Novosibirsk State Medical University of Minzdrav of Russia, Novosibirsk.
authors.forename: A V
authors.initials: AV
authors.lastname: Osadchii
authors.affiliation: Novosibirsk Tuberculosis Research Institute of Minzdrav of Russia.|Novosibirsk State Medical University of Minzdrav of Russia, Novosibirsk.
authors.forename: E V
authors.initials: EV
authors.lastname: Kulchavenya
mesh_terms: D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000503:physiopathology*; D008875:Middle Aged; D011446:Prospective Studies; D011472:Prostatitis / Q000150:complications / Q000503:physiopathology*; D012661:Semen / Q000737:chemistry / Q000166:cytology / Q000502:physiology*; D014389:Tuberculosis, Male Genital / Q000150:complications / Q000503:physiopathology*; D055815:Young Adult
keywords: ejaculate; infertility; metabolic syndrome; prostate; prostate gland; sperm; tuberculosis