title: Cardiogoniometry in psoriatic patients and its comparison with a control group.
abstract: BACKGROUND
  Cardiogoniometry (CGM), a spatiotemporal electrocardiologic method may be useful as a cardiovascular diagnostic tool. Increased incidence of coronary artery or myocardial involvement and defects in automatic setting of heart activity have been reported in psoriasis which could be related to the presence of systemic inflammation. Cardiogoniometry and the related parameters have been used in this study as a diagnostic technique in psoriasis patients.
  
  
  METHODS
  Thirty patients with psoriasis and 30 healthy, age and sex-matched individuals with no history of cardiovascular diseases or traditional coronary risk factors were enrolled. Duration and severity of the disease, using psoriasis severity and area index (PASI) score were recorded. Electrocardiography and cardiogoniometry were performed. Heart rate, QT interval and QT dispersion (QTD) were measured. SDNN (standard deviation of normal R-R interval) and myocardial ischemia score were determined by cardiogoniometry.
  
  
  RESULTS
  There was significant difference between the psoriasis patients and the controls in terms of heart rate (76.37±14.41 vs 72.53±9.684, p=0.02), myocardial ischemia score (-1.53±2.63 vs -0.46±0.73, p=0.037), corrected QT interval (392.64±26.00 vs 377.26±22.34, p=0.017) and QTD (32.00±17.88 vs 6.67±15.16, p<0.001). No statistically significant difference was found in SDNN (36.37±21.01 vs 26.90±14.88, p=.29). There were moderate correlation between PASI and SDNN (r=0.427, p=0.009), heart rate (r=0.427, p=.009) and score (r=0.481, p=.004).
  
  
  CONCLUSIONS
  Abnormalities in resting ECG and CGM and their correlation with disease severity raises concerns about the need for cardiovascular follow-ups of psoriatic patients, especially those with severe disease.
authors.affiliation: Atherosclerosis Prevention Research Center, Cardiovascular Department, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Hoorak
authors.initials: H
authors.lastname: Poorzand
authors.affiliation: Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: Kiafarb@mums.ac.ir.
authors.forename: Bita
authors.initials: B
authors.lastname: Kiafar
authors.affiliation: Atherosclerosis Prevention Research Center, Cardiovascular Department, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Fardideh
authors.initials: F
authors.lastname: Asadzadeh Heravi
authors.affiliation: Atherosclerosis Prevention Research Center, Cardiovascular Department, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Vejdanparast
authors.affiliation: Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Azadeh
authors.initials: A
authors.lastname: Saki
authors.affiliation: Atherosclerosis Prevention Research Center, Cardiovascular Department, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Tayebi
authors.affiliation: Imam Reza Clinical Research Unit, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Negar
authors.initials: N
authors.lastname: Morovatdar
authors.affiliation: Atherosclerosis Prevention Research Center, Cardiovascular Department, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Neda
authors.initials: N
authors.lastname: Karimabadi
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D035061:Control Groups; D003430:Cross-Sectional Studies; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000150:complications* / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Cardiogoniometry; Cardiovascular abnormality; Electrocardiography; Psoriasis; QT interval