title: Contact and Repellant Activities of Zerumbone and Its Analogues from the Essential Oil of Zingiber zerumbet (L.) Smith against Lasioderma serricorne.
abstract: The contact toxicity and repellent activities of the essential oil extracted from the rhizomes of Zingiber zerumbet (L.) Smith (Zingiberaceae) was evaluated against cigarette beetles (Lasioderma serricorne). The essential oil obtained by hydrodistillation was investigated by GC-FID and GC-MS. The main constituents of the essential oil were zerumbone (40.2%), α-caryophyllene (8.6%), humulene epoxide II (7.3%), camphene (5.9%) and fenchene (4.7%). Zerumbone and its analogues totally are accounting for 60.3% of the essential oil. It was found that the essential oil possessed contact toxicity against L. serricorne adults with a LD50value of 48.3 µg/adult. α-Caryophyllene (LD50= 13.1 µg/adult) exhibited stronger contact toxicity against L. serricorne than humulene oxide (LD50= 31.2 µg/adult), β-caryophyllene (LD50= 35.5 µg/adult) and zerumbone (LD50= 42.4 µg/adult). Moreover, α-caryophyllene possessed strong repellent activity (Class IV and V, respectively) against the beetles at 78.63 nL/cm2, after 2 and 4 h treatment. The results indicate that zerumbone and its analogues might be developed into natural insecticides or repellents for control of cigarette beetles, but their bioactivities are affected by their structures.
authors.affiliation: Technical Center of China Tobacco Guangxi Industrial Co., Ltd.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wu
authors.forename: Shan-Shan
authors.initials: SS
authors.lastname: Guo
authors.forename: Dong-Ye
authors.initials: DY
authors.lastname: Huang
authors.forename: Cheng-Fang
authors.initials: CF
authors.lastname: Wang
authors.forename: Jian-Yu
authors.initials: JY
authors.lastname: Wei
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Li
authors.forename: Jian-Sheng
authors.initials: JS
authors.lastname: Sun
authors.forename: Jia-Feng
authors.initials: JF
authors.lastname: Bai
authors.forename: Zhao-Fu
authors.initials: ZF
authors.lastname: Tian
authors.forename: Ping-Juan
authors.initials: PJ
authors.lastname: Wang
authors.forename: Shu-Shan
authors.initials: SS
authors.lastname: Du
mesh_terms: D000818:Animals; D001517:Coleoptera; D007302:Insect Repellents; D007306:Insecticides; D039821:Monoterpenes / Q000302:isolation & purification; D010938:Plant Oils / Q000302:isolation & purification; D012717:Sesquiterpenes / Q000302:isolation & purification; D030521:Zingiberaceae
chemical_list: D007302:Insect Repellents; D007306:Insecticides; D039821:Monoterpenes; D010938:Plant Oils; D012717:Sesquiterpenes; C403304:zerumbone