title: [Spermatogenesis recovery following allogeneic transplantation of undifferentiated Sertoli cells in experimental model of bilateral abdominal cryptorchidism].
abstract: This study explores the effect of transplantation of undifferentiated Sertoli cells in the testicular tissue of an experimental animal model of bilateral abdominal cryptorchidism. Effectiveness of undifferentiated Sertoli cell transplantation was assessed after 1 and 3 months after injection. Partial restoration of seminiferous tubules was found to occur after transplantation. In a third of them germ cells of all stages of the differentiation were discovered while they were not found in the control group.
authors.affiliation: Koltzov Institute of Developmental Biology of RAS.
authors.forename: A Yu
authors.initials: AY
authors.lastname: Kulibin
authors.affiliation: Koltzov Institute of Developmental Biology of RAS.|Gamaleya Scientific Research Institute of Epidemiology and Microbiology of Minzdrav of Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Malolina
authors.affiliation: Department of Reproductive Health of Scientific Center of Children's Health.
authors.forename: S P
authors.initials: SP
authors.lastname: Jacyk
authors.affiliation: Department of Reproductive Health of Scientific Center of Children's Health.
authors.forename: Je K
authors.initials: JK
authors.lastname: Zhamynchiev
authors.affiliation: Faculty of Medicine of the Peoples Friendship University of Russia.
authors.forename: G V
authors.initials: GV
authors.lastname: Kuzin
mesh_terms: D000818:Animals; D003456:Cryptorchidism / Q000628:therapy; D006801:Humans; D008297:Male; D008962:Models, Theoretical; D012671:Seminiferous Tubules; D012708:Sertoli Cells / Q000637:transplantation; D013091:Spermatogenesis; D013737:Testis; D014184:Transplantation, Homologous
keywords: cryptorchidism; pediatric uro-andrology; transplantation; undifferentiated Sertoli cells