title: A versatile size-coded flow cytometric bead assay for simultaneous detection of multiple microRNAs coupled with a two-step cascading signal amplification.
abstract: A versatile flow cytometric bead assay is developed for the sensitive and simultaneous detection of multiple microRNAs that combines an elegant enzyme-mediated cascading signal amplification on magnetic beads with a novel bead size-encoding mechanism.
authors.affiliation: Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, Shaanxi Province, P. R. China. liuch@snnu.edu.cn lzpbd@snnu.edu.cn.
authors.forename: Liying
authors.initials: L
authors.lastname: Qiu
authors.affiliation: Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, Shaanxi Province, P. R. China. liuch@snnu.edu.cn lzpbd@snnu.edu.cn and College of Chemistry and Chemical Engineering, Yan'an University, China.
authors.forename: Yuecheng
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, Shaanxi Province, P. R. China. liuch@snnu.edu.cn lzpbd@snnu.edu.cn.
authors.forename: Chenghui
authors.identifier: http://orcid.org/0000-0001-8375-0242
authors.initials: C
authors.lastname: Liu
authors.affiliation: Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, Shaanxi Province, P. R. China. liuch@snnu.edu.cn lzpbd@snnu.edu.cn.
authors.forename: Zhengping
authors.identifier: http://orcid.org/0000-0002-7573-8822
authors.initials: Z
authors.lastname: Li
mesh_terms: D055162:Biocatalysis; D004253:DNA Nucleotidylexotransferase / Q000378:metabolism*; D005434:Flow Cytometry; D035683:MicroRNAs / Q000032:analysis*; D010316:Particle Size
chemical_list: D035683:MicroRNAs; D004253:DNA Nucleotidylexotransferase