title: Medicinal plants used as anthelmintics: Ethnomedical, pharmacological, and phytochemical studies.
abstract: Intestinal parasites delay mental and physical development in children. Infection with these parasites can result in complications during pregnancy and alter the health of newborns, which has long-term effects on educational attainment and economic productivity. The appearance of resistance against classical drug treatments generates interest in the development of new deworming alternatives. We think that research of new plants species may reveal potential antiparasitic compounds. This review is focused on the use of plants and secondary metabolites against intestinal parasites. We discuss the use of plants in traditional medicine and the use of plant secondary metabolites tried in in vitro and in vivo models when available.
authors.affiliation: Departamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), San Cayetano alto s/n, CP:1101608, Loja, Ecuador; Programa Nacional para el Abordaje Multidisciplinario de las parasitosis desatendidas en el Ecuador PROPAD, Instituto Nacional de Investigaciones en Salud Pública LIP, Ecuador. Electronic address: jcromerob@utpl.edu.ec.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Romero-Benavides
authors.affiliation: Programa Nacional para el Abordaje Multidisciplinario de las parasitosis desatendidas en el Ecuador PROPAD, Instituto Nacional de Investigaciones en Salud Pública LIP, Ecuador; Facultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.
authors.forename: Ana Lucía
authors.initials: AL
authors.lastname: Ruano
authors.affiliation: Departamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), San Cayetano alto s/n, CP:1101608, Loja, Ecuador; Programa Nacional para el Abordaje Multidisciplinario de las parasitosis desatendidas en el Ecuador PROPAD, Instituto Nacional de Investigaciones en Salud Pública LIP, Ecuador.
authors.forename: Ronal
authors.initials: R
authors.lastname: Silva-Rivas
authors.affiliation: Departamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), San Cayetano alto s/n, CP:1101608, Loja, Ecuador; Programa Nacional para el Abordaje Multidisciplinario de las parasitosis desatendidas en el Ecuador PROPAD, Instituto Nacional de Investigaciones en Salud Pública LIP, Ecuador.
authors.forename: Paola
authors.initials: P
authors.lastname: Castillo-Veintimilla
authors.affiliation: Departamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), San Cayetano alto s/n, CP:1101608, Loja, Ecuador; Programa Nacional para el Abordaje Multidisciplinario de las parasitosis desatendidas en el Ecuador PROPAD, Instituto Nacional de Investigaciones en Salud Pública LIP, Ecuador.
authors.forename: Sara
authors.initials: S
authors.lastname: Vivanco-Jaramillo
authors.affiliation: Departamento de Ciencias de la Salud, Universidad Técnica Particular de Loja, San Cayetano alto s/n, CP:1101608, Loja, Ecuador.
authors.forename: Natalia
authors.initials: N
authors.lastname: Bailon-Moscoso
mesh_terms: D000871:Anthelmintics / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008519:Medicine, Traditional / Q000379:methods; D008517:Phytotherapy / Q000379:methods; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000871:Anthelmintics
keywords: Antihelmintic; Ethnomedicine; Plant extracts; Secondary metabolites