title: Detecting Swelling States of Red Blood Cells by "Cell-Fluid Coupling Spectroscopy".
abstract: Red blood cellsare "shaken" with a holographic optical tweezer array. The flow generated around cells due to the periodic optical forcing is measured with an optically trapped "detector" particle located in the cell vicinity. A signal-processing model that describes the cell's physical properties as an analog filter illustrates how cells can be distinguished from each other.
authors.affiliation: Photonics and Optoelectronics Group Department of Physics and Center for Nanoscience Ludwig-Maximilians-Universität Amalienstr. 5480799 Munich Germany; Photonics and Optoelectronics Group Nanosystems Initiative Munich (NIM) Schellingstraße 480799 Munich Germany.
authors.forename: Carla
authors.initials: C
authors.lastname: Zensen
authors.affiliation: Comprehensive Pneumology Center University Hospital of the Ludwig Maximilians Universität and Helmholtz Zentrum München Munich Germany 81377.
authors.forename: Isis E
authors.initials: IE
authors.lastname: Fernandez
authors.affiliation: Photonics and Optoelectronics Group Nanosystems Initiative Munich (NIM) Schellingstraße 480799 Munich Germany; Comprehensive Pneumology Center University Hospital of the Ludwig Maximilians Universität and Helmholtz Zentrum München Munich Germany 81377.
authors.forename: Oliver
authors.initials: O
authors.lastname: Eickelberg
authors.affiliation: Photonics and Optoelectronics Group Department of Physics and Center for Nanoscience Ludwig-Maximilians-Universität Amalienstr. 5480799 Munich Germany; Photonics and Optoelectronics Group Nanosystems Initiative Munich (NIM) Schellingstraße 480799 Munich Germany.
authors.forename: Jochen
authors.initials: J
authors.lastname: Feldmann
authors.affiliation: Photonics and Optoelectronics Group Department of Physics and Center for Nanoscience Ludwig-Maximilians-Universität Amalienstr. 5480799 Munich Germany; Photonics and Optoelectronics Group Nanosystems Initiative Munich (NIM) Schellingstraße 480799 Munich Germany.
authors.forename: Theobald
authors.initials: T
authors.lastname: Lohmüller
keywords: cell–fluid interaction; cytometry; microfluidics; optical tweezers; signal processing