title: A novel approach to segmentation and measurement of medical image using level set methods.
abstract: The study proposes a novel approach for segmentation and visualization plus value-added surface area and volume measurements for brain medical image analysis. The proposed method contains edge detection and Bayesian based level set segmentation, surface and volume rendering, and surface area and volume measurements for 3D objects of interest (i.e., brain tumor, brain tissue, or whole brain). Two extensions based on edge detection and Bayesian level set are first used to segment 3D objects. Ray casting and a modified marching cubes algorithm are then adopted to facilitate volume and surface visualization of medical-image dataset. To provide physicians with more useful information for diagnosis, the surface area and volume of an examined 3D object are calculated by the techniques of linear algebra and surface integration. Experiment results are finally reported in terms of 3D object extraction, surface and volume rendering, and surface area and volume measurements for medical image analysis.
authors.affiliation: Department of Applied Mobile Technology, Yuanpei University of Medical Technology, No. 306, Yuanpei St., HsinChu City 30015, Taiwan. Electronic address: ytchen@mail.ypu.edu.tw.
authors.forename: Yao-Tien
authors.initials: YT
authors.lastname: Chen
mesh_terms: D000465:Algorithms; D001499:Bayes Theorem; D001921:Brain / Q000000981:diagnostic imaging*; D001931:Brain Mapping / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D016011:Normal Distribution; D015203:Reproducibility of Results
keywords: Level set segmentation; Medical image; Modified marching cubes algorithm; Ray casting; Surface rendering; Volume rendering