title: New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE).
abstract: Repetitive DNA elements were proposed to coordinate chromatin folding and interaction in chromosomes by their intrinsic homology-based clustering ability. A recent analysis of the data sets from chromosome-conformation-capture experiments confirms the spatial clustering of DNA repeats of the same family in the nuclear space, and thus provides strong new support for the CORE theory.
authors.affiliation: Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555, USA. shtang@utmb.edu.
authors.forename: Shao-Jun
authors.initials: SJ
authors.lastname: Tang
keywords: CORE theory; chromatin; chromosome; chromosome conformation capture; repetitive DNA