title: Regio- and Enantioselective Photodimerization within the Confined Space of a Homochiral Ruthenium/Palladium Heterometallic Coordination Cage.
abstract: The photoinduced regio- and enantioselective coupling of naphthols and derivatives thereof is achieved in the confined chiral coordination space of a RuIImetalloligand based cage. The racemic or enantiopure cages encapsulate naphthol guests, which then undergo a regiospecific 1,4-coupling, rather than the normal 1,1-coupling, to form 4-(2-hydroxy-1-naphthyl)-1,2-napthoquinones; moderate stereochemical control is achieved with homochiral cages. The photoreactions proceed under both aerobic and anaerobic conditions but through distinct pathways that nevertheless involve the same radical intermediates. This unusual dimerization constitutes a very rare example of asymmetric induction in biaryl coupling by making use of coordination cages with dual functionality-photoredox reactivity and stereoselectivity.
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Guo
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Yao-Wei
authors.initials: YW
authors.lastname: Xu
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Kang
authors.initials: K
authors.lastname: Li
authors.affiliation: School of Computer Science and Engineering, Beihang University, Beijing, 100191, China.
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Xiao
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Sha
authors.initials: S
authors.lastname: Chen
authors.forename: Kai
authors.initials: K
authors.lastname: Wu
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Chen
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Yan-Zhong
authors.initials: YZ
authors.lastname: Fan
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Jun-Min
authors.initials: JM
authors.lastname: Liu
authors.affiliation: MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, and School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
authors.forename: Cheng-Yong
authors.identifier: 0000-0003-3604-7858
authors.initials: CY
authors.lastname: Su
keywords: coordination cages; couplings; homochiral cages; photoreactions; stereoselectivity