title: 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan in an Unusual Case of Lymphoma with Secondary Involvement of Uterine Cervix Presenting as a Pathological Fracture.
abstract: A 48-year-old female presented with a pathological fracture of the right femur.99mTc methylene diphosphonate bone scan revealed multiple areas of increased osteoblastic activity consistent with metastatic disease. Serum electrophoresis revealed monoclonal gammopathy.18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan revealed metabolically active lesions in bulky uterine cervix and osteolytic skeletal lesions. Unusual pattern of FDG uptake in uterine cervix and osteolytic skeletal lesions warranted a biopsy of the uterine cervix which revealed diffuse large B-cell lymphoma.18F-FDG PET/CT scan helped in guiding the site of biopsy to reach a final diagnosis in this unusual case of lymphoma with a secondary involvement of uterine cervix presenting as a pathological fracture.
authors.affiliation: Department of Nuclear Medicine and PET/CT, KIMS-DDNMRC, KIMS Hospital, Thiruvananthapuram, Kerala, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Sasikumar
authors.affiliation: Department of Nuclear Medicine and PET/CT, KIMS-DDNMRC, KIMS Hospital, Thiruvananthapuram, Kerala, India.
authors.forename: Ajith
authors.initials: A
authors.lastname: Joy
authors.affiliation: Department of Nuclear Medicine and PET/CT, KIMS-DDNMRC, KIMS Hospital, Thiruvananthapuram, Kerala, India.
authors.forename: M R A
authors.initials: MR
authors.lastname: Pillai
authors.affiliation: Department of Medical Oncology, KIMS Hospital, Thiruvananthapuram, Kerala, India.
authors.forename: Boben
authors.initials: B
authors.lastname: Thomas
keywords: 18F-fluorodeoxyglucose positron emission tomography/computed tomography; lymphoma; pathological fracture; uterine cervix