title: [DNA sequences from mobile genetic elements, a hidden half of the human genome].
abstract: Current data estimate that mobile genetic elements represent more than one-half of the human genome. The literature is constantly updating data following the evolution of sequencing techniques and of algorithms for genome analyses. This review aims to provide an overview of the topic showing the complexity given by the various designations and classifications found in scientific papers. A particular focus is made on retrotransposons, including Endogenous RetroViruses (ERV), to introduce a second article focusing on their activation and their involvement in physiological functions and/or pathological mechanisms associated with diseases like multiple sclerosis (MS) or amyotrophic lateral sclerosis (ALS).
authors.affiliation: GeNeuro Innovation, Bioparc Laënnec, 60, avenue Rockefeller, 69008 Lyon, France.
authors.forename: Julie
authors.initials: J
authors.lastname: Medina
authors.affiliation: GeNeuro Innovation, Bioparc Laënnec, 60, avenue Rockefeller, 69008 Lyon, France - GeNeuro, 18, chemin des Aulx, 1228 Plan-Les-Ouates, Genève, Suisse - Université Lyon-1, Faculté de Médecine Laënnec, 69008 Lyon, France.
authors.forename: Hervé
authors.initials: H
authors.lastname: Perron
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics; D000818:Animals; D001483:Base Sequence; D019143:Evolution, Molecular; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D020071:Interspersed Repetitive Sequences / Q000235:genetics*; D009103:Multiple Sclerosis / Q000235:genetics; D018626:Retroelements / Q000235:genetics; D017422:Sequence Analysis, DNA; D020079:Terminal Repeat Sequences
chemical_list: D018626:Retroelements