title: [IPSS-QOL questionnaire in assessing symptoms and quality of life in patients with anterior urethral stricture].
abstract: CONCLUSIONS
  The IPSS-QOL questionnaire is frequently used to assess symptoms and quality of life of men with urethral strictures. However, the psychometric properties of the questionnaire in assessing these patients have not been evaluated.
  
  
  OBJECTIVE
  To test the psychometric properties of the IPSS-QoL questionnaire in assessing patients with anterior urethral strictures.
  
  
  METHODS
  Thirty five men with anterior urethral strictures self-completed the IPSS-QoL questionnaire. The reliability of the questionnaire was estimated by computing Cronbachs coefficient and the "point-scale" correlation coefficients. Validity was assessed by the "external criteria" - the correlations between the questionnaire scores and objective indicators - maximum urinary flow rate (Qmax) and residual urine volume (Ures), between QoL scores and index values and EQ-5D scores using a VAS rating scale.
  
  
  RESULTS
  The content validity of the IPSS-QoL was assessed by experts and patients: the storage symptoms were found insignificant for patients with anterior urethral stricture, while the symptoms of primary importance (post-micturition dribbling) were not covered. Cronbachs coefficient of reliability was 0.65 (0.55-0.69 with one of the questions removed), i.e. it was below the generally accepted threshold of 0.7. The "point-scale" correlation coefficients ranged from 0.146 to 0.585; for 2 of the 7 questions they were lower, than the conventional threshold of 0.2, showing the internal inconsistencies of the questionnaire. The construct validity assessment showed no correlation between the questionnaire scores and objective indicators Qmax (R=0.178, p=0.306), Ures (R=-0.074, p=0.673). Correlations between QoL scores and index values and EQ-5D scores on the VAS were weak and statistically insignificant: R=-0.26, p=0.18 and R=-0.21, p=0.27, respectively.
  
  
  CONCLUSIONS
  IPSS-QoL questionnaire in assessing men with anterior urethral stricture does not have sufficient reliability and validity. Its design does not allow for adequate assessment of all the symptoms, reliability indices are unsatisfactory, the questionnaire scores do not correlate with objective indicators. This questionnaire cannot be recommended for evaluating health status and quality of life of this category of patients.
authors.affiliation: M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow.
authors.forename: V V
authors.initials: VV
authors.lastname: Bazaev
authors.affiliation: M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow.
authors.forename: A N
authors.initials: AN
authors.lastname: Shibaev
authors.affiliation: M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow.
authors.forename: Yu V
authors.initials: YV
authors.lastname: Pavlova
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014525:Urethral Stricture / Q000503:physiopathology* / Q000523:psychology*
keywords: PSS-QoL questionnaire; anterior urethral stricture; patient-reported outcomes; quality of life