title: Estimation of Right-Lobe Graft Weight From Computed Tomographic Volumetry for Living Donor Liver Transplantation.
abstract: BACKGROUND
  The objective of the study was to establish a right-lobe graft weight (GW) estimation formula for living donor liver transplantation (LDLT) from right-lobe graft volume without veins (GVw/o_veins), including portal vein and hepatic vein measured by computed tomographic (CT) volumetry, and to compare its estimation accuracy with those of existing formulas. Right-lobe GW estimation formulas established with the use of graft volume with veins (GVw_veins) sacrifice accuracy because GW measured intra-operatively excludes the weight of blood in the veins. Right-lobe GW estimation formulas have been established with the use of right-lobe GVw/o_veins, but a more accurate formula must be developed.
  
  
  METHODS
  The present study developed right-lobe GW estimation formulas based on GVw/o_veinsas well as GVw_veins, using 40 cases of Korean donors: GW = 29.1 + 0.943 × GVw/o_veins(adjusted R2= 0.94) and GW = 74.7 + 0.773 × GVw_veins(adjusted R2= 0.87). The proposed GW estimation formulas were compared with existing GVw_veins- and GVw/o_veins-based models, using 43 cases additionally obtained from two medical centers for cross-validation.
  
  
  RESULTS
  The GVw/o_veins-based formula developed in the present study was most preferred (absolute error = 21.5 ± 16.5 g and percentage of absolute error = 3.0 ± 2.3%).
  
  
  CONCLUSIONS
  The GVw/o_veins-based formula is preferred to the GVw_veins-based formula in GW estimation. Accurate CT volumetry and alignment between planned and actual surgical cutting lines are crucial in the establishment of a better GW estimation formula.
authors.affiliation: Department of Industrial Management and Engineering, Pohang University of Science and Technology, Pohang, Korea.
authors.forename: X
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Hepatopancreatobiliary Surgery and Liver Transplantation, Pusan National University Yangsan Hospital, Yangsan, Korea.
authors.forename: C W
authors.initials: CW
authors.lastname: Chu
authors.affiliation: Department of Surgery, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Jeonju, Korea; Biomedical Research Institute of Chonbuk University Hospital, Jeonju, Korea.
authors.forename: J D
authors.initials: JD
authors.lastname: Yang
authors.affiliation: Department of Hepatopancreatobiliary Surgery and Liver Transplantation, Pusan National University Yangsan Hospital, Yangsan, Korea.
authors.forename: K H
authors.initials: KH
authors.lastname: Yang
authors.affiliation: Department of Surgery, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Jeonju, Korea; Biomedical Research Institute of Chonbuk University Hospital, Jeonju, Korea. Electronic address: hcyu@jbnu.ac.kr.
authors.forename: H C
authors.initials: HC
authors.lastname: Yu
authors.affiliation: Department of Surgery, Chonbuk National University Medical School, Jeonju, Korea; Research Institute of Clinical Medicine of Chonbuk National University, Jeonju, Korea; Biomedical Research Institute of Chonbuk University Hospital, Jeonju, Korea.
authors.forename: B H
authors.initials: BH
authors.lastname: Cho
authors.affiliation: Department of Industrial Management and Engineering, Pohang University of Science and Technology, Pohang, Korea.
authors.forename: H
authors.initials: H
authors.lastname: You
mesh_terms: D000328:Adult; D005260:Female; D006503:Hepatic Veins / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D006801:Humans; D008099:Liver / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D009929:Organ Size; D011169:Portal Vein / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000592:standards; D060053:Transplant Donor Site / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D019737:Transplants / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D055815:Young Adult