title: Hybrid Surgery Options for Complex Clinical Scenarios in Adult Patients with Congenital Heart Disease: Three Case Reports.
abstract: The strategy for the management of adult patients with congenital heart disease (CHD) often represents a challenge for cardiac surgeons and cardiologists due to complex anatomy, wide range of clinical presentations, and a high-risk profile. However, hybrid approach may represent an attractive solution. We report three cases of adult patients previously operated for CHD and recently treated with a hybrid approach in our institution. Case 1: a 76-year-old woman with permanent atrial fibrillation, lung disease, chronic kidney disease, microcytic anemia, and type II diabetes mellitus, previously operated for atrial septal defect closure and pulmonary valvotomy, presented with severe pulmonary regurgitation and advanced right ventricular failure. In order to minimize the surgical risk, a hybrid approach was used: an extensive right ventricular outflow tract (RVOT) plication was followed by implantation of an Edwards Sapien XT prosthesis in the RVOT through the right ventricular apex, without cardiopulmonary bypass. Case 2: a 64-year-old man with previous atrial septum excision and pericardial baffle for partial anomalous pulmonary venous drainage with intact interatrial septum, presented with worsening dyspnea, right ventricular failure, and pulmonary hypertension caused by baffle stenosis. His comorbidities included coronary artery disease, atrial flutter, and previous left pneumonectomy. After performing a redo longitudinal median sternotomy, a 20-mm stent was implanted in the baffle with access through the superior vena cava. Case 3: a 50-year-old man, with previous atrioventricular septal defect repair, followed by mitral valve replacement with a mechanical prosthesis, subsequently developed a paravalvular leak (PVL) with severe mitral regurgitation and severe left ventricular dysfunction. He underwent a transapical PVL device closure with two Amplatzer Vascular Plugs. In our opinion, hybrid surgery is a promising therapeutic modality that increases the available treatment options for this patient population. A multidisciplinary and patient-tailored approach is crucial in these complex clinical scenarios.
authors.affiliation: Department of Cardiac Surgery, Bristol Heart Institute, University of Bristol, Bristol, UK; Department of Cardiac Surgery, Bristol Royal Hospital for Children, University of Bristol, Bristol, UK.
authors.forename: Filippo
authors.initials: F
authors.lastname: Rapetto
authors.affiliation: Department of Paediatric Cardiology, Rush University Medical Center , Chicago, IL , USA.
authors.forename: Damien
authors.initials: D
authors.lastname: Kenny
authors.affiliation: Department of Cardiology, Bristol Heart Institute, University of Bristol , Bristol , UK.
authors.forename: Mark
authors.initials: M
authors.lastname: Turner
authors.affiliation: Department of Cardiac Surgery, Bristol Heart Institute, University of Bristol, Bristol, UK; Department of Cardiac Surgery, Bristol Royal Hospital for Children, University of Bristol, Bristol, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: Parry
authors.affiliation: Department of Cardiac Surgery, Bristol Heart Institute, University of Bristol, Bristol, UK; Department of Cardiac Surgery, Bristol Royal Hospital for Children, University of Bristol, Bristol, UK.
authors.forename: Serban
authors.initials: S
authors.lastname: Stoica
authors.affiliation: Department of Paediatric Cardiology, University Hospital of Wales , Cardiff , UK.
authors.forename: Orhan
authors.initials: O
authors.lastname: Uzun
authors.affiliation: Department of Cardiac Surgery, Bristol Heart Institute, University of Bristol, Bristol, UK; Department of Cardiac Surgery, Bristol Royal Hospital for Children, University of Bristol, Bristol, UK.
authors.forename: Massimo
authors.initials: M
authors.lastname: Caputo
keywords: ACHD; cardiac surgery; hybrid surgery; paravalvular leak; pulmonary valve replacement