title: Moderate hypothermia technique for chronic implantation of a total artificial heart in calves.
abstract: The benefit of whole-body hypothermia in preventing ischemic injury during cardiac surgical operations is well documented. However, application of hypothermia during in vivo total artificial heart implantation has not become widespread because of limited understanding of the proper techniques and restrictions implied by constitutional and physiological characteristics specific to each animal model. Similarly, the literature on hypothermic set-up in total artificial heart implantation has also been limited. Herein we present our experience using hypothermia in bovine models implanted with the Cleveland Clinic continuous-flow total artificial heart.
authors.affiliation: Department of Biomedical Engineering/ND20, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA. karimoj@ccf.org.
authors.forename: Jamshid H
authors.initials: JH
authors.lastname: Karimov
authors.affiliation: Perfusion Services, Cardiac Surgery, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Patrick
authors.initials: P
authors.lastname: Grady
authors.affiliation: Perfusion Services, Cardiac Surgery, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Martin
authors.initials: M
authors.lastname: Sinkewich
authors.affiliation: Department of Biomedical Engineering/ND20, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
authors.forename: Gengo
authors.initials: G
authors.lastname: Sunagawa
authors.affiliation: Department of Biomedical Engineering/ND20, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
authors.forename: Raymond
authors.initials: R
authors.lastname: Dessoffy
authors.affiliation: Department of Biomedical Engineering/ND20, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Byram
authors.affiliation: Department of Biomedical Engineering/ND20, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.|Department of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Nader
authors.initials: N
authors.lastname: Moazami
authors.affiliation: Department of Biomedical Engineering/ND20, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA. fukamak@ccf.org.
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Fukamachi
mesh_terms: D000818:Animals; D006348:Cardiac Surgical Procedures; D002417:Cattle; D006354:Heart, Artificial; D007036:Hypothermia, Induced / Q000379:methods*; D023421:Models, Animal
keywords: Assisted circulation; Experimental surgery; Heart-assist devices; Hypothermia