title: Umbilical cord stem cells in the treatment of corneal disease.
abstract: Stem cells are capable of giving rise to progenies with specific functional and morphological traits and, in recent years, extraordinary scientific advances have initiated an era of hope for clinical regenerative strategies and tissue engineering applications. We appraise the potential benefits of human umbilical cord-derived stem cell therapy and consider current approaches to utilize these stem cells in corneal epithelial, stromal, and endothelial disorders.
authors.affiliation: Faculty of Medical and Health Sciences, Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Ziaei
authors.affiliation: Faculty of Medical and Health Sciences, Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Faculty of Medical and Health Sciences, Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand.
authors.forename: Dipika V
authors.initials: DV
authors.lastname: Patel
authors.affiliation: Faculty of Medical and Health Sciences, Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland, New Zealand. Electronic address: c.mcghee@auckland.ac.nz.
authors.forename: Charles N J
authors.initials: CNJ
authors.lastname: McGhee
mesh_terms: D003316:Corneal Diseases / Q000601:surgery*; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods; D059630:Mesenchymal Stem Cells; D033581:Stem Cell Transplantation / Q000379:methods*; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering / Q000379:methods; D014470:Umbilical Cord / Q000166:cytology*
keywords: cornea; human umbilical cord stem cells; mesenchymal stem cells; stem cell therapy; tissue regeneration; transplantation