title: Sympathetic ophthalmia in vater association combined with persisting hyperplastic primary vitreous after cyclodestructive procedure.
abstract: OBJECTIVE
  To report on the occurrence of histology-proven sympathetic ophthalmia in a patient with VATER association and persisting hyperplastic primary vitreous (PHPV) after a cyclodestructive procedure was performed to treat secondary angle-closure glaucoma.
  
  
  METHODS
  The left eye of a 13-year-old boy with VATER association was microphthalmic from birth and had been diagnosed with PHPV at age 1 year. It developed iris neovascularization and secondary angle-closure glaucoma, which was treated by combined cyclocryocoagulation and cyclophotocoagulation. Six weeks later, a bilateral fibrinous iritis developed. Despite intensive topical and systemic steroid treatment, the iritis persisted so that the left blind eye was enucleated.
  
  
  RESULTS
  Histology of the enucleated eye showed a marked intraocular inflammation with lymphocytes, epithelioid cells, and multinuclear giant cells grouped around remnants of melanin-bearing cells.
  
  
  CONCLUSIONS
  Sympathetic ophthalmia may occur in patients with VATER association and PHPV after a secondary angle-closure glaucoma is treated by a combined cyclocryocoagulation and cyclophotocoagulation. (Eur J Ophthalmol 2006; 16: 171-172).
authors.affiliation: Department of Ophthalmology, Faculty of Clinical Medicine Mannheim, Ruprecht-Karls-University of Hei.
authors.forename: J B
authors.initials: JB
authors.lastname: Jonas
authors.forename: W
authors.initials: W
authors.lastname: Back
authors.forename: G
authors.initials: G
authors.lastname: Sauder
authors.forename: U
authors.initials: U
authors.lastname: Junemann
authors.forename: B
authors.initials: B
authors.lastname: Harder
authors.forename: U H
authors.initials: UH
authors.lastname: Spandau