title: Hereditary Renal Tumor Syndromes: Update on Diagnosis and Management.
abstract: Hereditary renal cancers account for approximately 5%-8% of all renal tumors. Over the past 2 decades, a number of syndromes have been identified that predispose patients to early renal cancer development, representing all the major histologic types of tumor pathology. In this article, we describe the current knowledge concerning the cell type, known mechanism of tumor development, other manifestations of the syndrome, imaging findings, genetic screening, and imaging surveillance recommendations for each of the major syndromes associated with hereditary renal cancers.
authors.affiliation: Molecular Imaging Program, National Cancer Institute, Bethesda, MD; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA.
authors.forename: Sonia
authors.initials: S
authors.lastname: Gaur
authors.affiliation: Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA.
authors.forename: Baris
authors.initials: B
authors.lastname: Turkbey
authors.affiliation: Molecular Imaging Program, National Cancer Institute, Bethesda, MD. Electronic address: pchoyke@nih.gov.
authors.forename: Peter
authors.initials: P
authors.lastname: Choyke
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy*; D009386:Neoplastic Syndromes, Hereditary / Q000000981:diagnostic imaging* / Q000628:therapy*