title: Efficacy of a morantel-abamectin combination for the treatment of resistant ascarids in foals.
abstract: BACKGROUND
  This study was performed to investigate the efficacy of a morantel-abamectin combination for the treatment of macrocyclic lactone (ML)-resistant Parascaris spp. infections in foals.
  
  
  METHODS
  Foals on five properties with a Parascaris faecal egg count (FEC) > 50 eggs per gram were used to estimate the FEC reduction (FECR) and efficacy of the anthelmintic combination.
  
  
  CONCLUSIONS
  On all properties, resistance to ivermectin and abamectin was present and the Parascaris FECR in foals administered the morantel-abamectin combination was > 99%, indicating that this combination effectively controlled ML-resistant parasites.
authors.affiliation: School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia.
authors.forename: Eja
authors.initials: E
authors.lastname: Wilkes
authors.affiliation: Ceva Animal Health Pty Ltd, Glenorie, NSW, Australia.
authors.forename: F F
authors.initials: FF
authors.lastname: McConaghy
authors.affiliation: School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia.
authors.forename: R L
authors.initials: RL
authors.lastname: Thompson
authors.affiliation: Dawbuts Pty Ltd, Camden, NSW, Australia.
authors.forename: K
authors.initials: K
authors.lastname: Dawson
authors.affiliation: School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia.
authors.forename: N C
authors.initials: NC
authors.lastname: Sangster
authors.affiliation: School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia.
authors.forename: K J
authors.initials: KJ
authors.lastname: Hughes
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017191:Ascaridida Infections / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D001199:Ascaridoidea / Q000187:drug effects*; D004338:Drug Combinations; D004351:Drug Resistance; D006734:Horse Diseases / Q000188:drug therapy* / Q000469:parasitology; D006736:Horses / Q000469:parasitology; D007559:Ivermectin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009015:Morantel / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000969:Antinematodal Agents; D004338:Drug Combinations; C048324:abamectin; D007559:Ivermectin; D009015:Morantel
keywords: 
  Parascaris spp; anthelmintics; horses; resistance; roundworms