title: Malaria impact of large dams at different eco-epidemiological settings in Ethiopia.
abstract: BACKGROUND
  Dams are important to ensure food security and promote economic development in sub-Saharan Africa. However, a poor understanding of the negative public health consequences from issues such as malaria could affect their intended advantages. This study aims to compare the malaria situation across elevation and proximity to dams. Such information may contribute to better understand how dams affect malaria in different eco-epidemiological settings.
  
  
  METHODS
  Larval and adult mosquitoes were collected from dam and non-dam villages around the Kesem (lowland), Koka (midland), and Koga (highland) dams in Ethiopia between October 2013 and July 2014. Determination of blood meal sources and detection ofPlasmodium falciparumsporozoites was done using enzyme-linked immunosorbent assay (ELISA). Five years of monthly malaria case data (2010-2014) were also collected from health centers in the study villages.
  
  
  RESULTS
  Mean monthly malaria incidence was two- and ten-fold higher in the lowland dam village than in midland and highland dam villages, respectively. The total surface area of anopheline breeding habitats and the mean larval density was significantly higher in the lowland dam village compared with the midland and highland dam villages. Similarly, the mean monthly malaria incidence and anopheline larval density was generally higher in the dam villages than in the non-dam villages in all the three dam settings.Anopheles arabiensis,Anopheles pharoensis, andAnopheles funestus s.l.were the most common species, largely collected from lowland and midland dam villages. Larvae of these species were mainly found in reservoir shoreline puddles and irrigation canals. The mean adult anopheline density was significantly higher in the lowland dam village than in the midland and highland dam villages. The annual entomological inoculation rate (EIR) ofAn. arabiensis,An. funestus s.l., andAn. pharoensisin the lowland dam village was 129.8, 47.8, and 33.3 infective bites per person per annum, respectively. The annual EIR ofAn. arabiensisandAn. pharoensiswas 6.3 and 3.2 times higher in the lowland dam village than in the midland dam village.
  
  
  CONCLUSIONS
  This study found that the presence of dams intensifies malaria transmission in lowland and midland ecological settings. Dam and irrigation management practices that could reduce vector abundance and malaria transmission need to be developed for these regions.
authors.affiliation: Ecosystem Management, School of Environmental and Rural Science, University of New England, Armidale, NSW 2351 Australia.|Present address: Program in Public Health, University of California, Irvine, CA 92697 USA.
authors.forename: Solomon
authors.identifier: 0000-0003-1793-6908
authors.initials: S
authors.lastname: Kibret
authors.affiliation: Ecosystem Management, School of Environmental and Rural Science, University of New England, Armidale, NSW 2351 Australia.
authors.forename: G Glenn
authors.initials: GG
authors.lastname: Wilson
authors.affiliation: Ecosystem Management, School of Environmental and Rural Science, University of New England, Armidale, NSW 2351 Australia.
authors.forename: Darren
authors.initials: D
authors.lastname: Ryder
authors.affiliation: Department of Zoological Sciences, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.
authors.forename: Habte
authors.initials: H
authors.lastname: Tekie
authors.affiliation: Department of Microbial, Cellular and Molecular Biology, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.
authors.forename: Beyene
authors.initials: B
authors.lastname: Petros
keywords: Africa; An. arabiensis; An. funestus; An. pharoensis; Dams; Irrigation; Malaria; Mosquito breeding; Water management