title: Evaluation of Outcome of Transpedicular Decompression and Instrumented Fusion in Thoracic and Thoracolumbar Tuberculosis.
abstract: METHODS
  Retrospective analysis.
  
  
  OBJECTIVE
  We evaluated the functional, neurological, and radiological outcome in patients with thoracic and thoracolumbar tuberculosis operated through the transpedicular approach.
  
  
  BACKGROUND
  For surgical treatment of thoracic and thoracolumbar tuberculosis, the anterior approach has been the most popular because it allows direct access to the infected tissue, thereby providing good decompression. However, anterior fixation is not strong, and graft failure and loss of correction are frequent complications. The transpedicular approach allows circumferential decompression of neural elements along with three-column fixation attained via pedicle screws by the same approach.
  
  
  METHODS
  A total of 47 patients were diagnosed with tuberculosis of the thoracic or thoracolumbar region from August 2012 to August 2013. Of these, 28 patients had progressive neurological deterioration or increasing back pain despite conservative measures and underwent transpedicular decompression and pedicle screw fixation with posterior fusion. Antituberculosis therapy was given till signs of radiological healing were evident (9-16 months). Functional outcome (visual analog scale [VAS] score for back pain), neurological recovery (Frankel grading), and radiological improvement were evaluated preoperatively, immediate postoperatively, and at 3 months, 6 months, and 1 year.
  
  
  RESULTS
  Mean VAS score for back pain improved from 8.7 preoperatively to 1.1 at 1 year follow-up. Frankel grading preoperatively was grade B in 7, grade C in 11, and Grade D in 10 patients, which improved to grade D in 6 and grade E in 22 patients at the last follow-up. Radiological healing was evident in the form of reappearance of trabeculae formation, resolution of pus, fatty marrow replacement, and bony fusion in all patients. Mean correction of segmental kyphosis postoperatively was 10.5°. Mean loss of correction at final follow-up was 4.1°.
  
  
  CONCLUSIONS
  Transpedicular decompression with instrumented fusion is a safe and effective approach for management of patients with thoracic and thoracolumbar tuberculosis.
authors.affiliation: Department of Orthopedics, Shri Aurobindo Institute of Medical Sciences, Indore, India.
authors.forename: Akshay
authors.initials: A
authors.lastname: Jain
authors.affiliation: Department of Orthopedics, Shri Aurobindo Institute of Medical Sciences, Indore, India.
authors.forename: R K
authors.initials: RK
authors.lastname: Jain
authors.affiliation: Department of Orthopedics, Shri Aurobindo Institute of Medical Sciences, Indore, India.
authors.forename: Vivek
authors.initials: V
authors.lastname: Kiyawat
keywords: Decompression; Spinal tuberculosis; Transpedicular