title: Appetitive and aversive motivation in dysphoria: A time-domain and time-frequency study of response inhibition.
abstract: The study of emotional response inhibition could provide novel insight into dysphoria-related deficits in appetitive and aversive motivational systems. Therefore, dysphoric (N=21) and nondysphoric (N=21) participants completed an emotional Go/Nogo paradigm, including the presentation of pleasant, neutral and unpleasant pictures. Behavioral measures [reaction times (RTs), accuracy to Go and Nogo stimuli] and neural correlates (Go/Nogo-N2 and Go/Nogo-P3) of response inhibition were compared between the two groups. Time-frequency analysis was also used as a novel approach to disentangle the multiple processes underlying time-domain ERP data. A reduced Go/Nogo effect for P3 and oscillatory delta activity was found in response to pleasant and neutral, but not unpleasant, stimuli in dysphoric relative to nondysphoric individuals. These findings showed that dysphoric individuals need a reduced and/or less effortful response inhibition to pleasant stimuli, suggesting that dysphoria is characterized by under-engagement of appetitive rather than over-engagement of aversive motivational system.
authors.affiliation: Department of General Psychology, University of Padova, Via Venezia, 8, 35131, Padova, Italy. Electronic address: simone.messerotti@unipd.it.
authors.forename: Simone
authors.initials: S
authors.lastname: Messerotti Benvenuti
authors.affiliation: Department of General Psychology, University of Padova, Via Venezia, 8, 35131, Padova, Italy; Center for Cognitive Neuroscience, University of Padova, Via Venezia, 8, 35131, Padova, Italy. Electronic address: giulia.buodo@unipd.it.
authors.forename: Giulia
authors.initials: G
authors.lastname: Buodo
authors.affiliation: Department of General Psychology, University of Padova, Via Venezia, 8, 35131, Padova, Italy; Center for Cognitive Neuroscience, University of Padova, Via Venezia, 8, 35131, Padova, Italy. Electronic address: daniela.palomba@unipd.it.
authors.forename: Daniela
authors.initials: D
authors.lastname: Palomba
mesh_terms: D000328:Adult; D000339:Affect; D003863:Depression / Q000523:psychology*; D004569:Electroencephalography; D004644:Emotions / Q000502:physiology*; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006801:Humans; D007266:Inhibition, Psychological; D008297:Male; D009042:Motivation; D011930:Reaction Time / Q000502:physiology*; D013996:Time and Motion Studies; D055815:Young Adult
keywords: Dysphoria; Event-related potentials; Motivation; Response inhibition; Time-frequency delta activity