title: Social deprivation and stroke severity on admission: a French cohort study in Burgundy and the West Indies - Guyana region.
abstract: Although there is growing and convincing evidence that socially deprived patients are at higher risk of stroke and worse outcomes, it remains controversial whether or not they suffer more severe stroke. This study aimed to evaluate the influence of social deprivation on initial clinical severity in patients with stroke.
  
  
  
  A total of 1536 consecutive patients with an acute first-ever stroke (both ischaemic stroke and intracerebral hemorrhage) were prospectively enrolled from six French study centers. Stroke severity on admission was measured by the National Institutes of Health Stroke Scale score. Social deprivation was assessed at the individual level by the Evaluation de la Précarité et des Inégalités de santé dans les Centres d'Examen de Santé (EPICES) score, a validated multidimensional questionnaire, and several additional single socioeconomic indicators. Polytomous logistic regression analyses were performed to evaluate the association between social deprivation and stroke severity.
  
  
  
  In univariate analysis, the EPICES score (P = 0.039) and level of education (P = 0.018) were the only two socioeconomic variables associated with stroke severity. Multivariate analysis of the association between EPICES and National Institutes of Health Stroke Scale scores showed that more deprived patients presented a significantly higher risk of both mild and moderate/severe stroke (odds ratio for mild versus minor stroke, 1.39; 95% confidence interval, 1.06-1.84; odds ratio for moderate/severe versus minor stroke, 1.44; 95% confidence interval, 1.09-1.92). A non-significant trend towards a higher risk of both mild and moderate/severe stroke in less educated patients was observed.
  
  
  
  Social deprivation was associated with a more severe clinical presentation in patients with stroke. These findings may contribute to the worse outcome after stroke in deprived patients, and underline the need for strategies to reduce social inequalities for stroke.
authors.affiliation: Neurology Department and Dijon Stroke Registry, University Hospital of Dijon, Dijon.|Bourgogne-Franche-Comté University, Dijon.
authors.forename: Y
authors.initials: Y
authors.lastname: Béjot
authors.affiliation: Clinical Investigation Center, University Hospital of Dijon, Dijon.|Inserm CIC 1432, Dijon.
authors.forename: A
authors.initials: A
authors.lastname: Guilloteau
authors.affiliation: Neurology Department, University Hospital of Martinique, Fort-de-France.
authors.forename: J
authors.initials: J
authors.lastname: Joux
authors.affiliation: Neurology Department, University Hospital of Pointe-à-Pitre, Pointe-à-Pitre.|University of West Indies, Pointe-à-Pitre.|UMR 1127, Institute for Brain and Spinal Cord Disorders, ICM, Paris.
authors.forename: A
authors.initials: A
authors.lastname: Lannuzel
authors.affiliation: Emergency Department, Hospital Andrée Rosemon, Cayenne.
authors.forename: E
authors.initials: E
authors.lastname: Mimeau
authors.affiliation: Medicine Department, Western Guyana Hospital, Saint Laurent du Maroni, France.
authors.forename: C
authors.initials: C
authors.lastname: Mislin-Tritsch
authors.affiliation: Bourgogne-Franche-Comté University, Dijon.|Clinical Investigation Center, University Hospital of Dijon, Dijon.|Inserm CIC 1432, Dijon.
authors.forename: I
authors.initials: I
authors.lastname: Fournel
authors.affiliation: Bourgogne-Franche-Comté University, Dijon.|Clinical Investigation Center, University Hospital of Dijon, Dijon.|Inserm CIC 1432, Dijon.
authors.forename: C
authors.initials: C
authors.lastname: Bonithon-Kopp
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000150:complications; D002543:Cerebral Hemorrhage / Q000209:etiology; D015331:Cohort Studies; D005260:Female; D005602:France / Q000208:ethnology; D005616:French Guiana / Q000208:ethnology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011610:Psychosocial Deprivation; D020521:Stroke / Q000208:ethnology* / Q000503:physiopathology*; D014900:West Indies / Q000208:ethnology
keywords: clinical study; educational status; epidemiology; prognosis; psychosocial deprivation; stroke