title: Metastatic Cellular Blue Nevus: A Rare Case With Metastasis Beyond Regional Nodes.
abstract: In this study, we present a rare case of a 35-year-old man with a long-standing blue-black lesion on his left hand with subsequent infraclavicular and axillary lymph node tumor deposits. The hand lesion and lymph nodes were excised revealing histological, immunohistochemical, and molecular findings consistent with cellular blue nevus. Despite nonregional lymph node involvement, there has been no progression at 12-months follow-up. This is an index case of a cellular blue nevus with metastasis to both regional and nonregional lymph nodes. The lack of atypical/malignant features in this lesion makes the metastatic behavior extraordinary, and hence the prognosis of lesions of this type is indeterminate.
authors.affiliation: *Fiona Stanley Hospital, Murdoch, WA; †Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Perth, Western Australia, Australia; ‡St John of God Hospitals (Subiaco, Murdoch, Midland and Mt Lawley); §Department of Medical Oncology, Fiona Stanley Hospital, Murdoch, WA; and ¶School of Medicine and Pharmacology, University of Western Australia, Nedlands, WA.
authors.forename: Justin
authors.initials: J
authors.lastname: Bui
authors.forename: Nima Mesbah
authors.initials: NM
authors.lastname: Ardakani
authors.forename: Irene
authors.initials: I
authors.lastname: Tan
authors.forename: Andrew
authors.initials: A
authors.lastname: Crocker
authors.forename: Muhammad Adnan
authors.initials: MA
authors.lastname: Khattak
authors.forename: Benjamin A
authors.initials: BA
authors.lastname: Wood
mesh_terms: D000328:Adult; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D018329:Nevus, Blue / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*