title: Investigation on the ability of heteroatom-doped graphene for biorecognition.
abstract: Doped graphene platforms have been attracting considerable attention due to their improved electrochemical performances. Recent studies have shown the advantage of using either p-type or n-type doped graphene materials as transducers for the detection of various electroactive probes. Here we wanted to take a step forward and extend the study to investigate the ability of heteroatom doped graphene as an electrochemical platform for biorecognition. To this aim, a boron-doped graphene, a nitrogen-doped graphene and an undoped graphene material prepared under similar conditions were employed for the detection of fumonisin B1, a highly carcinogenic mycotoxin found in food commodities. We found that the material structural features, such as the amount of oxygen functionalities, had a stronger influence on the sensitivity of biorecognition rather than the kind and amount of dopant. Our findings may be essential for the choice of a proper platform for the assessment of food safety.
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. a.bonanni@ntu.edu.sg.
authors.forename: Huidi
authors.initials: H
authors.lastname: Tian
authors.affiliation: Department of Inorganic Chemistry, Institute of Chemical Technology, 166 28 Prague 6, Czech Republic.
authors.forename: Zdenek
authors.identifier: http://orcid.org/0000-0002-1391-4448
authors.initials: Z
authors.lastname: Sofer
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. a.bonanni@ntu.edu.sg.
authors.forename: Martin
authors.identifier: http://orcid.org/0000-0001-5846-2951
authors.initials: M
authors.lastname: Pumera
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. a.bonanni@ntu.edu.sg.
authors.forename: Alessandra
authors.identifier: http://orcid.org/0000-0001-8214-6748
authors.initials: A
authors.lastname: Bonanni
mesh_terms: D015374:Biosensing Techniques; D001895:Boron; D055664:Electrochemical Techniques; D037341:Fumonisins / Q000032:analysis; D006108:Graphite / Q000737:chemistry*; D009584:Nitrogen; D010100:Oxygen
chemical_list: D037341:Fumonisins; C056933:fumonisin B1; D006108:Graphite; D009584:Nitrogen; D001895:Boron; D010100:Oxygen