title: Metabolic brain adaptations to recurrent hypoglycaemia may explain the link between type 1 diabetes mellitus and epilepsy and point towards future study and treatment options.
authors.affiliation: Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, P.O. Box 208020, New Haven, CT, 06520, USA.
authors.forename: Domenico
authors.identifier: http://orcid.org/0000-0002-7633-1346
authors.initials: D
authors.lastname: Tricò
authors.affiliation: Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, P.O. Box 208020, New Haven, CT, 06520, USA. raimund.herzog@yale.edu.
authors.forename: Raimund I
authors.initials: RI
authors.lastname: Herzog
mesh_terms: D001812:Blood-Brain Barrier; D016022:Case-Control Studies; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000503:physiopathology*; D004827:Epilepsy / Q000150:complications* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000150:complications / Q000503:physiopathology; D007659:Ketones; D008297:Male; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D007659:Ketones
keywords: Brain metabolism; Epilepsy; Hypoglycaemia; Lactate; Type 1 diabetes; β-hydroxybutyrate