title: Risk Factors and Prediction Models for Retinopathy of Prematurity.
abstract: OBJECTIVE
  To develop a simple prediction model for the pre-screening of Retinopathy of Prematurity (ROP) among preterm babies.
  
  
  METHODS
  This was a prospective study. The test dataset (January 2007 until December 2010) was used to construct risk prediction models, and the validation dataset (January 2011 until March 2012) was used to validate the models developed from the test dataset. Two prediction models were produced using the test dataset based on logistic regression equations in which the development of ROP was used as the outcome.
  
  
  RESULTS
  The sensitivity and specificity for model 1 [gestational age (GA), birth weight (BW), intraventricular haemorrhage (IVH) and respiratory distress syndrome (RDS)] was 82 % and 81.7%, respectively; for model 2, (GA and BW) the sensitivity and specificity were 80.5% and 80.3%, respectively.
  
  
  CONCLUSIONS
  Model 2 was preferable, as it only required two predictors (GA and BW). Our prediction model can be used for early detection of ROP to avoid poor outcomes.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine and Health Sciences, University Malaysia Sarawak (UNIMAS), Lot 77, Seksyen 22, Kuching Town Land District, Jalan Tun Ahmad Zaidi Adruce, 93150 Kuching, Sarawak, Malaysia.
authors.forename: Mallika Prem
authors.initials: MP
authors.lastname: Senthil
authors.affiliation: Department of Ophthalmology, Sarawak General Hospital, 93150 Kuching, Sarawak, Malaysia.
authors.forename: Mohamad Aziz
authors.initials: MA
authors.lastname: Salowi
authors.affiliation: Biostatistics Unit, Clinical Research Centre, Level 3 Dermatology Block, Hospital Kuala Lumpur, Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
authors.forename: Mohamad Adam
authors.initials: MA
authors.lastname: Bujang
authors.affiliation: Department of Ophthalmology, Sarawak General Hospital, 93150 Kuching, Sarawak, Malaysia.
authors.forename: Adeline
authors.initials: A
authors.lastname: Kueh
authors.affiliation: Department of Ophthalmology, Sarawak General Hospital, 93150 Kuching, Sarawak, Malaysia.
authors.forename: Chong Min
authors.initials: CM
authors.lastname: Siew
authors.affiliation: Department of Ophthalmology, Sarawak General Hospital, 93150 Kuching, Sarawak, Malaysia.
authors.forename: Kala
authors.initials: K
authors.lastname: Sumugam
authors.affiliation: Departments of Pediatrics, Sarawak General Hospital, Kuching, 93150 Kuching, Sarawak, Malaysia.
authors.forename: Chan Lee
authors.initials: CL
authors.lastname: Gaik
authors.affiliation: Department of Ophthalmology, Faculty of Medicine and Health Sciences, University Malaysia Sarawak (UNIMAS), Lot 77, Seksyen 22, Kuching Town Land District, Jalan Tun Ahmad Zaidi Adruce, 93150 Kuching, Sarawak, Malaysia.
authors.forename: Tan Aik
authors.initials: TA
authors.lastname: Kah
keywords: model; prediction; prematurity; retinopathy; risk