title: Wavelet-based scaling indices for breast cancer diagnostics.
abstract: Mammography is routinely used to screen for breast cancer. However, the radiological interpretation of mammogram images is complicated by the heterogeneous nature of normal breast tissue and the fact that cancers are often of the same radiographic density as normal tissue. In this work, we use wavelets to quantify spectral slopes of breast cancer cases and controls and demonstrate their value in classifying images. In addition, we propose asymmetry statistics to be used in forming features, which improve the classification result. For the best classification procedure, we achieve approximately 77% accuracy (sensitivity=73%, specificity=84%) in classifying mammograms with and without cancer. Copyright © 2017 John Wiley & Sons, Ltd.
authors.affiliation: H. Milton Stewart School of Industrial & Systems Engineering, Georgia Institute of Technology, 765 Ferst Drive NW, Atlanta, GA, 30332, U.S.A.
authors.forename: T
authors.identifier: 0000-0002-5254-6190
authors.initials: T
authors.lastname: Roberts
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1365 Clifton Road NE, Suite AT-504, Atlanta, GA, 30322, U.S.A.
authors.forename: M
authors.initials: M
authors.lastname: Newell
authors.affiliation: Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1365 Clifton Road NE, Suite AT-504, Atlanta, GA, 30322, U.S.A.
authors.forename: W
authors.initials: W
authors.lastname: Auffermann
authors.affiliation: H. Milton Stewart School of Industrial & Systems Engineering, Georgia Institute of Technology, 765 Ferst Drive NW, Atlanta, GA, 30332, U.S.A.
authors.forename: B
authors.initials: B
authors.lastname: Vidakovic
mesh_terms: D000704:Analysis of Variance; D001940:Breast / Q000000981:diagnostic imaging; D001943:Breast Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D058067:Wavelet Analysis
keywords: classification; mammography; scaling; wavelets