title: A Review of Diagnosis of GERD.
abstract: The prevalence of gastroesophageal reflux disease (GERD) and the incidence of some of its complications have risen strikingly over the last few decades. With the accumulation in our understanding on the pathophysiology of GERD along with the development of proton pump inhibitors, the diagnostic and therapeutic approaches to the GERD have changed dramatically over the past decade. However, The GERD still poses a problem to many clinicians since the spectrum of the disease has evolved to encompass more challenging presentations such as refractory GERD and extraesophageal manifestations. The aim of this article was to provide a review of available current diagnostic tests of the GERD, includes proton pump inhibitor test, ambulatory pH monitoring, impedance pH monitoring, mucosa impedance, and high resolution manometry. This review discusses different modalities for the work up of GERD.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
authors.forename: In Du
authors.initials: ID
authors.lastname: Jeong
mesh_terms: D016099:Endoscopy, Gastrointestinal; D000071041:Esophageal Mucosa / Q000473:pathology; D050782:Esophageal pH Monitoring; D005753:Gastric Mucosa / Q000473:pathology; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D054328:Proton Pump Inhibitors / Q000627:therapeutic use
chemical_list: D054328:Proton Pump Inhibitors
keywords: Esophageal pH monitoring; Gastroesophageal reflux disease; Impedance pH monitoring; Mucosa impedance; Proton pump inhibitor test