title: Hypertrophic Pachymeningitis and the Syndrome of Inappropriate Antidiuretic Hormone Secretion: Coincidence or Cause?
abstract: OBJECTIVE
  To investigate a potential cause of the syndrome of inappropriate antidiuretic hormone secretion (SIADH).
  
  
  METHODS
  A 70-year-old female patient had nausea and collapsed. Although euvolemic, pathological laboratory findings showed hyponatremia and hypoosmolality, and cerebral magnetic resonance imaging showed hypertrophic pachymeningitis. Secondary hypertrophic pachymeningitis was excluded. Other nonneurological reasons for SIADH were also excluded. Moderate fluid restriction restored an almost normal serum osmolality and sodium.
  
  
  CONCLUSIONS
  This case of SIADH was conservatively treated with moderate fluid restriction that almost restored normal serum osmolality and sodium levels.
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine II, Thuringia Clinic Saalfeld, Saalfeld, Germany.
authors.forename: Igor Alexander
authors.initials: IA
authors.lastname: Harsch
authors.forename: Anne
authors.initials: A
authors.lastname: Schiffer
authors.forename: Peter C
authors.initials: PC
authors.lastname: Konturek
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D006984:Hypertrophy; D007010:Hyponatremia / Q000150:complications; D007177:Inappropriate ADH Syndrome / Q000150:complications* / Q000628:therapy; D008581:Meningitis / Q000150:complications* / Q000628:therapy
keywords: Hypertrophic pachymeningitis; Hyponatremia; Syndrome of inappropriate antidiuretic hormone secretion