title: The Role of Heated Humidified High-flow Nasal Cannula as Noninvasive Respiratory Support in Neonates.
abstract: Recently, heated humidified high-flow nasal cannula (HHHFNC) has been introduced and applied as a noninvasive respiratory support in neonates. Although HHHFNC is widely used in neonates presenting with respiratory distress, the efficiency and safety when compared with nasal continuous positive airway pressure or noninvasive positive pressure ventilation are still controversial. This review aims to evaluate the performance and applications of HHHFNC in neonates.
authors.affiliation: Department of Pediatrics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; Department of Respiratory Therapy, Fu Jen Catholic University, Taipei, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University Taoyuan, Taiwan.
authors.forename: Ke-Yun
authors.initials: KY
authors.lastname: Chao
authors.affiliation: Department of Pediatrics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; School of Medicine, Taipei Medical University, Taipei, Taiwan.
authors.forename: Yi-Ling
authors.initials: YL
authors.lastname: Chen
authors.affiliation: Department of Pediatrics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; College of Public Health, Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University, Taipei, Taiwan.
authors.forename: Li-Yi
authors.initials: LY
authors.lastname: Tsai
authors.affiliation: Department of Pediatrics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
authors.forename: Yu-Hsuan
authors.initials: YH
authors.lastname: Chien
authors.affiliation: Department of Pediatrics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; School of Medicine, Fu Jen Catholic University, Taipei, Taiwan. Electronic address: musc1004@gmail.com.
authors.forename: Shu-Chi
authors.initials: SC
authors.lastname: Mu
mesh_terms: D000072601:Cannula; D045422:Continuous Positive Airway Pressure; D006358:Hot Temperature; D006801:Humans; D000068998:Humidifiers; D007231:Infant, Newborn; D007234:Infant, Premature; D063087:Noninvasive Ventilation; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*
keywords: heated humidified high-flow nasal cannula; infant; nasal continuous positive airway pressure; non-invasive positive pressure ventilation