title: Mycobacterium tuberculosis Infection among Asian Elephants in Captivity.
abstract: Although awareness of tuberculosis among captive elephants is increasing, antituberculosis therapy for these animals is not standardized. We describe Mycobacterium tuberculosis transmission between captive elephants based on whole genome analysis and report a successful combination treatment. Infection control protocols and careful monitoring of treatment of captive elephants with tuberculosis are warranted.
authors.forename: Gary
authors.initials: G
authors.lastname: Simpson
authors.forename: Ralph
authors.initials: R
authors.lastname: Zimmerman
authors.forename: Elena
authors.initials: E
authors.lastname: Shashkina
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
authors.forename: Michael
authors.initials: M
authors.lastname: Richard
authors.forename: Carol M
authors.initials: CM
authors.lastname: Bradford
authors.forename: Gwen A
authors.initials: GA
authors.lastname: Dragoo
authors.forename: Rhonda L
authors.initials: RL
authors.lastname: Saiers
authors.forename: Charles A
authors.initials: CA
authors.lastname: Peloquin
authors.forename: Charles L
authors.initials: CL
authors.lastname: Daley
authors.forename: Paul
authors.initials: P
authors.lastname: Planet
authors.forename: Apurva
authors.initials: A
authors.lastname: Narachenia
authors.forename: Barun
authors.initials: B
authors.lastname: Mathema
authors.forename: Barry N
authors.initials: BN
authors.lastname: Kreiswirth
mesh_terms: D000818:Animals; D000836:Animals, Zoo; D004269:DNA, Bacterial / Q000235:genetics; D004606:Elephants; D016680:Genome, Bacterial; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D014376:Tuberculosis / Q000382:microbiology / Q000662:veterinary*
chemical_list: D004269:DNA, Bacterial
keywords: Asian elephants; Elephas maximus; Mycobacterium tuberculosis; bacteria; bacterial infection; transmission; tuberculosis and other mycobacteria; whole-genome sequencing; zoonoses