title: A prevalent CTLA4 missense variant significantly associates with inhibitor development in Argentine patients with severe haemophilia A.
authors.affiliation: Instituto de Medicina Experimental (IMEX) CONICET-Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: V D
authors.identifier: 0000-0002-0009-1884
authors.initials: VD
authors.lastname: Marchione
authors.affiliation: CIPYP (Centro de Investigaciones sobre Porfirinas y Porfirias), Buenos Aires, Argentina.
authors.forename: J R
authors.initials: JR
authors.lastname: Zuccoli
authors.affiliation: Instituto de Medicina Experimental (IMEX) CONICET-Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: M M
authors.initials: MM
authors.lastname: Abelleyro
authors.affiliation: Instituto de Medicina Experimental (IMEX) CONICET-Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: C P
authors.initials: CP
authors.lastname: Radic
authors.affiliation: Fundación de la Hemofilia Alfredo Pavlovsky, Buenos Aires, Argentina.
authors.forename: D
authors.initials: D
authors.lastname: Neme
authors.affiliation: Instituto de Investigaciones Hematológicas Mariano R Castex, Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Candela
authors.affiliation: Fundación de la Hemofilia Alfredo Pavlovsky, Buenos Aires, Argentina.|Instituto de Investigaciones Hematológicas Mariano R Castex, Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: de Tezanos Pinto
authors.affiliation: Instituto de Medicina Experimental (IMEX) CONICET-Academia Nacional de Medicina, Buenos Aires, Argentina.|Instituto de Investigaciones Hematológicas Mariano R Castex, Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: C D
authors.initials: CD
authors.lastname: De Brasi
authors.affiliation: Instituto de Medicina Experimental (IMEX) CONICET-Academia Nacional de Medicina, Buenos Aires, Argentina.
authors.forename: L C
authors.initials: LC
authors.lastname: Rossetti
mesh_terms: D001118:Argentina; D060908:CTLA-4 Antigen / Q000235:genetics*; D005169:Factor VIII / Q000276:immunology; D005838:Genotype; D006467:Hemophilia A / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology*; D006801:Humans; D020125:Mutation, Missense
chemical_list: D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; D005169:Factor VIII