title: Enhanced depth OCT imaging of the lamina cribrosa for 24 hours.
abstract: The lamina cribrosa thickness (LCT) could be affected by dynamic changes in its structure. Using Spectral-domain-optical coherence tomography (SD-OCT), we have studied the behaviour of the laminar region in 14 young subjects over 24h. Significant changes in LCT were observed, depending on the time at which the measurement was taken, with the maximum thickness being observed at 7.30 p.m., and the minimum at 7.30 a.m. This finding could suggests a circadian pattern in the LCT thickness in healthy subjects, which could have implications for the classification, diagnosis and prognosis of both normal and glaucomatous subjects.
authors.affiliation: Department of Ophthalmology, Reina Sofia University Hospital, Córdoba 14004, Spain.
authors.forename: Pedro
authors.initials: P
authors.lastname: Naranjo-Bonilla
authors.affiliation: Department of Ophthalmology, Reina Sofia University Hospital, Córdoba 14004, Spain.
authors.forename: Rafael
authors.initials: R
authors.lastname: Giménez-Gómez
authors.affiliation: Department of Ophthalmology, Reina Sofia University Hospital, Córdoba 14004, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Ríos-Jiménez
authors.affiliation: Department of Ophthalmology, Reina Sofia University Hospital, Córdoba 14004, Spain.
authors.forename: María Luísa
authors.initials: ML
authors.lastname: Varas-Fabra
authors.affiliation: Methodological Support to Research, Maimonides Institute for Biomedical Research, Reina Sofía University Hospital, Córdoba 14004, Spain.
authors.forename: María Del Carmen
authors.initials: MD
authors.lastname: Muñoz-Villanueva
authors.affiliation: Department of Ophthalmology, Reina Sofia University Hospital, Córdoba 14004, Spain.
authors.forename: Rocío
authors.initials: R
authors.lastname: García-Catalán
authors.affiliation: Department of Medicine UCO, Maimonides Institute for Biomedical Research, Reina Sofía University Hospital, Córdoba 14004, Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: Font-Ugalde
authors.affiliation: Department of Morphological Sciences, Faculty of Medicine, Cordoba 14004, Spain.
authors.forename: María Soledad
authors.initials: MS
authors.lastname: Poblador-Fernández
authors.affiliation: Department of Morphological Sciences, Faculty of Medicine, Cordoba 14004, Spain.
authors.forename: José Luís
authors.initials: JL
authors.lastname: Lancho-Alonso
authors.affiliation: Department of Ophthalmology, Reina Sofia University Hospital, Córdoba 14004, Spain.
authors.forename: José María
authors.initials: JM
authors.lastname: Gallardo-Galera
keywords: glaucoma; lamina cribrosa; laminar region; optical coherence tomography; twenty-four-hours