title: Advances in industrial microbiome based on microbial consortium for biorefinery.
abstract: One of the important targets of industrial biotechnology is using cheap biomass resources. The traditional strategy is microbial fermentations with single strain. However, cheap biomass normally contains so complex compositions and impurities that it is very difficult for single microorganism to utilize availably. In order to completely utilize the substrates and produce multiple products in one process, industrial microbiome based on microbial consortium draws more and more attention. In this review, we first briefly described some examples of existing industrial bioprocesses involving microbial consortia. Comparison of 1,3-propanediol production by mixed and pure cultures were then introduced, and interaction relationships between cells in microbial consortium were summarized. Finally, the outlook on how to design and apply microbial consortium in the future was also proposed.
authors.affiliation: School of Life Science and Biotechnology, Dalian University of Technology, Linggong Road 2, Dalian, 116024 Liaoning Province China.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Jiang
authors.affiliation: School of Life Science and Biotechnology, Dalian University of Technology, Linggong Road 2, Dalian, 116024 Liaoning Province China.
authors.forename: Jin-Jie
authors.initials: JJ
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Biotechnology and Bioresources Utilization, College of Life Science, Dalian Minzu University, Liaohe West Road 18, Jinzhou New District, Dalian, 116600 Liaoning Province China.
authors.forename: Chun-Shan
authors.initials: CS
authors.lastname: Quan
authors.affiliation: School of Life Science and Biotechnology, Dalian University of Technology, Linggong Road 2, Dalian, 116024 Liaoning Province China.
authors.forename: Zhi-Long
authors.initials: ZL
authors.lastname: Xiu
keywords: Bio-based chemicals; Biofuels; Biomass; Biorefinery; Industrial microbiome; Microbial consortia