title: Impacts of disease severity on postoperative complications in children with sleep-disordered breathing.
abstract: To investigate the effects of diseases severity on postoperative complications following adenotonsillectomy (T&A) in children with sleep-disordered breathing (SDB).
  
  
  
  Retrospective study.
  
  
  
  Children aged <18 years were enrolled and underwent T&A for treating SDB. Polysomnography was used to classify the disease severity: primary snoring (apnea-hypopnea index [AHI] <1), mild (AHI = 1-5), moderate (AHI = 5-10), and severe obstructive sleep apnea [OSA] (AHI ≥10). Postoperative bleeding was graded using a severity scale (level I, self-reported bleeding; level II, requiring inpatient admission; level III, requiring reoperation). Primary bleeding is defined as hemorrhage occurring within the initial 24 postoperative hours. Perioperative respiratory complications are defined as oxygen saturation of less than 90%, 92%, or 95% in the recovery room. Major respiratory complications include laryngospasm, pulmonary edema, pneumonia, and intubation at recovery stage.
  
  
  
  A total of 610 children were included, of whom 42 (6.9%), eight (1.3%), and six (1.0%) children showed levels I, II, and III postoperative bleeding, respectively. Only one child had primary bleeding. The incidence and timing of postoperative bleeding did not differ significantly for children with different OSA severities. The rate of perioperative respiratory complications ranged from 1.6% to 14.3% on the basis of their definitions. The Cochran-Armitage test supported the trend that perioperative respiratory complications increase with the AHI. Six children developed major respiratory complications, which were not significantly associated with OSA severity.
  
  
  
  Children with severe OSA have increased risks of perioperative respiratory complications. However, OSA severity does not influence major respiratory complications or postoperative bleeding in children.
  
  
  
  4. Laryngoscope, 127:2646-2652, 2017.
authors.affiliation: Department of Otolaryngology, National Taiwan University, College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.|Department of Otolaryngology, Taipei Hospital, Ministry of Health and Welfare, New Taipei City, Taiwan.
authors.forename: Kun-Tai
authors.initials: KT
authors.lastname: Kang
authors.affiliation: Department of Otolaryngology, National Taiwan University, College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: I-Sheng
authors.initials: IS
authors.lastname: Chang
authors.affiliation: Department of Otolaryngology, National Taiwan University, College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Chia-Chen
authors.initials: CC
authors.lastname: Tseng
authors.affiliation: Sleep Center, National Taiwan University Hospital, Taipei, Taiwan.|Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Wen-Chin
authors.initials: WC
authors.lastname: Weng
authors.affiliation: Department of Otolaryngology, National Taiwan University, College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Tzu-Yu
authors.initials: TY
authors.lastname: Hsiao
authors.affiliation: Sleep Center, National Taiwan University Hospital, Taipei, Taiwan.|Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Pei-Lin
authors.initials: PL
authors.lastname: Lee
authors.affiliation: Department of Otolaryngology, National Taiwan University, College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.|Sleep Center, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Wei-Chung
authors.initials: WC
authors.lastname: Hsu
mesh_terms: D000233:Adenoidectomy; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D011183:Postoperative Complications / Q000453:epidemiology*; D019106:Postoperative Hemorrhage / Q000453:epidemiology; D012140:Respiratory Tract Diseases / Q000453:epidemiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D012891:Sleep Apnea Syndromes / Q000503:physiopathology* / Q000601:surgery*; D013624:Taiwan / Q000453:epidemiology; D014068:Tonsillectomy
chemical_list: D010100:Oxygen
keywords: Adenoidectomy; child; polysomnography; postoperative complications; sleep apnea syndromes; tonsillectomy