title: DNA condensation in live E. coli provides evidence for transertion.
abstract: Condensation studies of chromosomal DNA in E. coli with a tetranuclear ruthenium complex are carried out and images obtained with wide-field fluorescence microscopy. Remarkably different condensate morphologies resulted, depending upon the treatment protocol. The occurrence of condensed nucleoid spirals in live bacteria provides evidence for the transertion hypothesis.
authors.affiliation: School of Physical, Environmental and Mathematical Sciences, University of New South Wales, Australian Defence Force Academy, Canberra, ACT 2600, Australia. g.collins@adfa.edu.au c.woodward@adfa.edu.au.
authors.forename: Anil K
authors.initials: AK
authors.lastname: Gorle
authors.affiliation: The ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW 2007, Australia.
authors.forename: Amy L
authors.initials: AL
authors.lastname: Bottomley
authors.affiliation: The ithree institute, University of Technology Sydney, PO Box 123, Broadway, NSW 2007, Australia.
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Harry
authors.affiliation: School of Physical, Environmental and Mathematical Sciences, University of New South Wales, Australian Defence Force Academy, Canberra, ACT 2600, Australia. g.collins@adfa.edu.au c.woodward@adfa.edu.au.
authors.forename: J Grant
authors.initials: JG
authors.lastname: Collins
authors.affiliation: Centre for Biodiscovery & Molecular Development of Therapeutics, James Cook University, Townsville, QLD 4811, Australia and School of Physical Sciences, University of Adelaide, Adelaide, SA 5066, Australia. richard.keene@adelaide.edu.au.
authors.forename: F Richard
authors.identifier: http://orcid.org/0000-0001-7759-0465
authors.initials: FR
authors.lastname: Keene
authors.affiliation: School of Physical, Environmental and Mathematical Sciences, University of New South Wales, Australian Defence Force Academy, Canberra, ACT 2600, Australia. g.collins@adfa.edu.au c.woodward@adfa.edu.au.
authors.forename: Clifford E
authors.initials: CE
authors.lastname: Woodward
mesh_terms: D002876:Chromosomes, Bacterial / Q000187:drug effects; D004269:DNA, Bacterial / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D008856:Microscopy, Fluorescence; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology; D012270:Ribosomes / Q000378:metabolism; D012428:Ruthenium / Q000737:chemistry
chemical_list: D004269:DNA, Bacterial; D009942:Organometallic Compounds; D012428:Ruthenium