title: [Recurrence of Well Differentiated Intrascrotal Liposarcoma in Retroperitoneum Five Years after Resection : A Case Report].
abstract: A 68-year-old man underwent an inguinal orchiectomy for a right testicular tumor and the pathological diagnosis was atypical lipomatous tumor. Nine years later, a resection procedure was performed for local recurrence. Five years after that second surgery, abdominal computed tomography (CT) findings revealed a low density mass 40 mm in size on the back side of the right kidney and enlarged fat in the retroperitoneal space. We performed a laparoscopic tumor resection under a diagnosis of lipoma or liposarcoma recurrence, and the pathological diagnosis was well differentiated liposarcoma. Treatment with pazopanib was started, as a CT examination showed that the tumor remained, after which we performed an open nephroureterectomy and resected the remaining tumor portion. Pazopanib treatment was continued and no obvious signs of recurrence were seen at 8 months after the most recent surgery. Although well differentiated liposarcoma usually recurs in the original tumor region, multicentric recurrence in other parts is possible.
authors.affiliation: The Department of Urology, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Yoshinaga
authors.affiliation: The Department of Urology, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Sekii
authors.affiliation: The Department of Urology, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Nakazawa
authors.affiliation: The Department of Urology, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakagawa
authors.affiliation: The Department of Urology, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Kishikawa
authors.affiliation: The Department of Urology, Hyogo Prefectural Nishinomiya Hospital.
authors.forename: Kenji
authors.initials: K
authors.lastname: Nishimura
mesh_terms: D000368:Aged; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D006801:Humans; D007191:Indazoles; D008080:Liposarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008297:Male; D009919:Orchiectomy; D011743:Pyrimidines / Q000627:therapeutic use; D012008:Recurrence; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D013449:Sulfonamides / Q000627:therapeutic use; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D020533:Angiogenesis Inhibitors; D007191:Indazoles; D011743:Pyrimidines; D013449:Sulfonamides; C516667:pazopanib