title: One-pot carbonization synthesis of europium-doped carbon quantum dots for highly selective detection of tetracycline.
abstract: The detection of tetracycline is of great significance because of its damaging effects on human health, such as renal toxicity and hemolytic anemia. Any release of tetracycline into the surrounding environment can produce bacterial drug resistance. We develop a new sensitive and selective detection approach for tetracycline in complex water samples by preparing europium-doped carbon quantum dots (Eu-CQDs) through a simple and rapid carbonization method operating at 200 °C for 5 min. The Eu-CQDs are characterized by blue photoluminescence, excitation-wavelength-dependent emission and excellent stability. Importantly, the fluorescence of the Eu-CQDs can be quenched efficiently by tetracycline, based on the strong inner filter effect mechanism between Eu-CQDs and tetracycline, making the fluorescence intensity ratio (I0/I) of the Eu-CQDs at 465 nm correlate linearly with the concentration of tetracycline in the range of 0.5-200 μM, with a limit of detection of 0.3 μM. This shows the broad applicability of the Eu-CQDs in pursuing the concepts of simplicity and specificity for analytical purposes.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, People's Republic of China.
authors.forename: Meng
authors.initials: M
authors.lastname: Li Liu
authors.forename: Bin Bin
authors.initials: BB
authors.lastname: Chen
authors.forename: Tong
authors.initials: T
authors.lastname: Yang
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Xi
authors.initials: X
authors.lastname: Dong Liu
authors.forename: Cheng
authors.initials: C
authors.lastname: Zhi Huang
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D005063:Europium / Q000737:chemistry*; D005453:Fluorescence; D045663:Quantum Dots / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013752:Tetracycline / Q000032:analysis* / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D014874:Water Pollutants, Chemical; D005063:Europium; D002244:Carbon; D013752:Tetracycline