title: Visual Acuity, Retinal Sensitivity, and Macular Thickness Changes in Diabetic Patients without Diabetic Retinopathy after Cataract Surgery.
abstract: Aim. Functional and morphological macular study after cataract surgery in a group of diabetics without diabetic retinopathy compared to nondiabetics to evaluate the effect of surgical oxidative stress on diabetic retina.Methods. Prospective, comparative study. Preoperative eye exam, best corrected visual acuity (BCVA) measured by ETDRS letters, and optical coherence tomography (OCT) were followed by standard cataract surgery. The follow-up visits at 1, 3, and 6 months postoperatively included BCVA, OCT, and microperimetry, to analyze changes within and between the groups.Results. The BCVA improved significantly in diabetics and controls: 64.2 to 81.0 and 61.9 to 82.1 ETDRS at 6 months, respectively. The central macula at OCT significantly thickened in both groups, while the central 5 fields, corresponding to the microperimetry area, subclinically thickened from 284.20 to 291.18μm at 6 months only in diabetics (p= 0.026). A matching slight decrease in the microperimetry sensitivity from 1 to 6 months was found also only in diabetics, with mean average difference -0.75 dB (p= 0.04).Conclusion. Underlying diabetes does not influence the surgical outcome in diabetics without diabetic retinopathy. However, slight thickening of wider macula and corresponding decrease in retinal sensitivity observed in diabetics 6 months postoperatively might influence visual function on long term.
authors.affiliation: Eye Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia.
authors.forename: Spela
authors.identifier: 0000-0002-1778-2913
authors.initials: S
authors.lastname: Stunf Pukl
authors.affiliation: Eye Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia.
authors.forename: Nataša
authors.identifier: 0000-0003-4136-8242
authors.initials: N
authors.lastname: Vidović Valentinčič
authors.affiliation: Eye Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia.
authors.forename: Mojca
authors.identifier: 0000-0001-8007-834X
authors.initials: M
authors.lastname: Urbančič
authors.affiliation: Eye Center Irman, Žalec, Slovenia.
authors.forename: Irena
authors.initials: I
authors.lastname: Irman Grčar
authors.affiliation: Eye Center Irman, Žalec, Slovenia.
authors.forename: Rok
authors.initials: R
authors.lastname: Grčar
authors.affiliation: Eye Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Pfeifer
authors.affiliation: Eye Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
authors.forename: Mojca
authors.identifier: 0000-0002-8427-4513
authors.initials: M
authors.lastname: Globočnik Petrovič
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002387:Cataract Extraction; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000000981:diagnostic imaging / Q000503:physiopathology*; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*