title: Frontal Fibrosing Alopecia Coexisting with Lupus Erythematosus: Poor Response to Hydroxychloroquine.
abstract: Lupus erythematosus, especially the discoid form, and lichen planopilaris may be associated and can occur in different topographies (coexistence) or in the same lesion (lupus eythematosus/lichen planus overlap syndrome). Frontal fibrosing alopecia is considered a variant form of lichen planopilaris and is characterized by frontotemporal hairline and eyebrow involvement. Of the association with lupus erythematosus we have only a few descriptions. Hydroxychloroquine and chloroquine diphosphate are antimalarial drugs described as viable treatment options for both diseases, due to an antilymphocytic effect. The association between frontal fibrosing alopecia and lupus erythematosus (discoid or systemic) is reported in this article, showing a progressive alopecia in the frontotemporal hairline despite treatment with hydroxychloroquine.
authors.affiliation: Dermatology Clinic, Hospital do Servidor Público Municipal de São Paulo, São Paulo, Brazil.
authors.forename: Letícia Arsie
authors.initials: LA
authors.lastname: Contin
authors.affiliation: Dermatology Clinic, Hospital do Servidor Público Municipal de São Paulo, São Paulo, Brazil.
authors.forename: Elisa Raquel
authors.initials: ER
authors.lastname: Martins da Costa Marques
authors.affiliation: Dermatology Clinic, Hospital do Servidor Público Municipal de São Paulo, São Paulo, Brazil.
authors.forename: Leandro
authors.initials: L
authors.lastname: Noriega
keywords: Cicatricial alopecia; Frontal fibrosing alopecia; Hydroxychloroquine; Lupus erythematosus