title: Weight loss and alterations in co-morbidities after revisional gastric bypass: A case-matched study from the Scandinavian Obesity Surgery Registry.
abstract: BACKGROUND
  In Sweden, Roux-en-Y gastric bypass is the most common procedure when revising a previous bariatric procedure. This study is an analysis of all revisional gastric bypass operations (rGBP) compared with a matched group of primary gastric bypass (pGBP) operated between 2007 and 2012.
  
  
  OBJECTIVE
  The aim was to determine whether improvement of obesity-related co-morbidity and changes in weight after revisional gastric bypass surgery were comparable with those seen after primary surgery.
  
  
  METHODS
  44 hospitals in Sweden METHODS: Retrospective data were retrieved from the Scandinavian Obesity Surgery Registry. The study group (rGBP) comprised 1224 patients, and the control group (pGBP) comprised 3612 patients matched for age and gender.
  
  
  RESULTS
  The indication for revision was weight failure in 512 patients (42%), a late complication of the initial procedure in 330 patients (27%), and a combination of weight failure and complication in 303 patients (25%). A total of 66% of patients in the rGBP group and 67% in the pGBP group completed the 2-year follow-up in the Scandinavian Obesity Surgery Registry. The rGBP-group had significantly less excess BMI loss (%EBMIL 59.4±147.0 versus 79.5±24.7, P<.001) and a lower dyslipidemia remission rate (42.9% versus 62.0%, P = .005) at the time of the 2-year follow-up. Remission rates of sleep apnea, hypertension, type 2 diabetes, and depression were similar. The effects on obesity-related co-morbidity were not related to the indication for revisional surgery or the initial bariatric procedure.
  
  
  CONCLUSIONS
  Even if weight results might be inferior compared with primary bypass procedures, the improvement of co-morbidity is similar.
authors.affiliation: Faculty of Medicine and Health, Örebro University, Örebro, Sweden. Electronic address: stephan.axer@liv.se.
authors.forename: Stephan
authors.initials: S
authors.lastname: Axer
authors.affiliation: Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
authors.forename: Eva
authors.initials: E
authors.lastname: Szabo
authors.affiliation: Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
authors.forename: Ingmar
authors.initials: I
authors.lastname: Näslund
mesh_terms: D015992:Body Mass Index; D016022:Case-Control Studies; D003866:Depressive Disorder / Q000150:complications / Q000503:physiopathology; D050171:Dyslipidemias / Q000150:complications / Q000503:physiopathology; D005260:Female; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D011446:Prospective Studies; D012042:Registries; D012086:Reoperation / Q000706:statistics & numerical data; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000503:physiopathology; D013548:Sweden; D015431:Weight Loss / Q000502:physiology*
keywords: Bariatric surgery; Co-morbidities; Diabetes; Gastric bypass; Revision; Weight loss