title: Broad scope gold(i)-catalysed polyenyne cyclisations for the formation of up to four carbon-carbon bonds.
abstract: The polycyclisation of polyenynes catalyzed by gold(i) has been extended for the first time to the simultaneous formation of up to four carbon-carbon bonds, leading to steroid-like molecules with high stereoselectivity in a single step with low catalyst loadings. In addition to terminal alkynes, bromoalkynes can also be used as initiators of polyene cyclisations, giving rise to synthetically useful cyclic bromoalkenes.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007 Tarragona, Spain. aechavarren@iciq.es.
authors.forename: Zhouting
authors.initials: Z
authors.lastname: Rong
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007 Tarragona, Spain. aechavarren@iciq.es and Departament de QuímicaAnalítica i QuímicaOrgànica, UniversitatRovira i Virgili, C/ Marcel·li Domingo s/n, 43007 Tarragona, Spain.
authors.forename: Antonio M
authors.identifier: http://orcid.org/0000-0001-6808-3007
authors.initials: AM
authors.lastname: Echavarren