title: The Presentation of a Fussy Infant With Bruising: Late-Onset Vitamin K Deficiency Bleeding.
abstract: Vitamin K plays an integral role in the clotting cascade. Deficiency, specifically in vulnerable neonates with insufficient stores, can lead to spontaneous bleeding and devastating effects. In this case, we report a young infant with late-onset vitamin K deficiency bleeding who did not receive vitamin K prophylaxis after birth. Initially presenting with bruising and fussiness, the patient was later found to have intracerebral hemorrhage with midline shift and uncal herniation. The infant was not a surgical candidate and died shortly thereafter. Laboratory studies confirmed the diagnosis of late-onset vitamin K deficiency bleeding as the cause of hemorrhage and death.
authors.affiliation: From the Department of Pediatrics and.
authors.forename: Katherine
authors.initials: K
authors.lastname: Wolpert
authors.affiliation: Division of Pediatric Emergency Medicine, University of Utah, Salt Lake City, UT.
authors.forename: Matthew
authors.initials: M
authors.lastname: Szadkowski
authors.affiliation: Division of Pediatric Emergency Medicine, University of Utah, Salt Lake City, UT.
authors.forename: Michael
authors.initials: M
authors.lastname: Miescier
authors.affiliation: Division of Pediatric Emergency Medicine, University of Utah, Salt Lake City, UT.
authors.forename: Hilary A
authors.initials: HA
authors.lastname: Hewes
mesh_terms: D003288:Contusions / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D020300:Intracranial Hemorrhages / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D014057:Tomography, X-Ray Computed; D006475:Vitamin K Deficiency Bleeding / Q000150:complications / Q000175:diagnosis*