title: Immunoglobulin G4-Related Periaortitis Involving the Aortic Arch Mimicking a Mediastinal Tumor.
abstract: Immunoglobulin G4 (IgG4)-related sclerosing disease is a recently proposed systemic fibroinflammatory disease entity, with periaortitis as a representative manifestation in the cardiovascular system. We present a case of IgG4-related periaortitis involving the aortic arch and proximal great vessels, mimicking an anterior mediastinal tumor on computed tomography. In patients with a soft tissue mass along the aortic wall, IgG4-related periaortitis should be included as a differential diagnosis and timely serologic investigation should be performed to prevent unnecessary surgery, because the disease shows a remarkable response to corticosteroids.
authors.affiliation: Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
authors.forename: Min Jae
authors.initials: MJ
authors.lastname: Cha
authors.affiliation: Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea. Electronic address: smchong@cau.ac.kr.
authors.forename: Semin
authors.initials: S
authors.lastname: Chong
authors.affiliation: Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
authors.forename: Yang Soo
authors.initials: YS
authors.lastname: Kim
authors.affiliation: Department of Thoracic Surgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
authors.forename: Byungjoon
authors.initials: B
authors.lastname: Park
authors.affiliation: Department of Pathology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
authors.forename: Ja Hee
authors.initials: JH
authors.lastname: Seo
authors.affiliation: Department of Nuclear Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
authors.forename: Eun Sung
authors.initials: ES
authors.lastname: Lee
mesh_terms: D001013:Aorta, Thoracic / Q000000981:diagnostic imaging / Q000473:pathology*; D001025:Aortitis / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D007074:Immunoglobulin G