title: Excessive serous retinal detachment during the use of isotretinoin.
abstract: OBJECTIVE
  To report a case unilateral excessive subretinal fluid during the use of isotretinoin.
  
  
  METHODS
  A case report. A patient who used isotretinoin orally for nodular-cystic acne vulgaris developed concurrent unilaterally excessive subretinal fluid and serous retinal detachment.
  
  
  RESULTS
  Fluorescein angiography did not demonstrate the leakage points throughout the subretinal fluid. Spectral-domain optical coherence tomography showed the excessive subretinal fluid and serous retinal detachment at macula. Two weeks after presentation, visual acuity was partially increased and subretinal fluid was disappeared at macula.
  
  
  CONCLUSIONS
  İsotretinoin may affect the functioning of the RPE and can cause the development of subretinal fluid and serous retinal detachment.
authors.affiliation: Ankara Ulucanlar Eye Education and Research Hospital, Ulucanlar Cd. No: 59, 06230, Altindag, Ankara, Turkey. mcitirik@hotmail.com.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Citirik
authors.affiliation: Ankara Ulucanlar Eye Education and Research Hospital, Ulucanlar Cd. No: 59, 06230, Altindag, Ankara, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Tekin
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000293:Adolescent; D003879:Dermatologic Agents / Q000009:adverse effects*; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects*; D008297:Male; D012163:Retinal Detachment / Q000139:chemically induced*
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin
keywords: Acne; Isotretinoin; Subretinal fluid