title: Synchronous melanomas arising within nevus spilus.
abstract: Nevus spilus is a melanocytic cutaneous lesion consisting of a light brown background macule with numerous superimposed darker maculopapular speckles. Melanoma arising from a nevus spilus is rare, with less than 40 cases reported to date. The absolute risk for malignant transformation is not well defined, lacking a standardized management approach. We report a new case of melanoma arising from nevus spilus, with the additional peculiarity of multifocality. We offer our recommendations for the management of the condition.
authors.affiliation: Department of Dermatology, Santarém Hospital - Santarém, Portugal.
authors.forename: Maria Helena Toda Sanches de
authors.initials: MH
authors.lastname: Brito
authors.affiliation: Department of Dermatology, Instituto Português de Oncologia de Lisboa - Lisboa, Portugal.
authors.forename: Cecília Silva Nunes de Moura
authors.initials: CS
authors.lastname: Dionísio
authors.affiliation: Department of Dermatology, Hospital de Santo António dos Capuchos, Centro Hospitalar de Lisboa Central - Lisboa, Portugal.
authors.forename: Cândida Margarida Branco Martins
authors.initials: CM
authors.lastname: Fernandes
authors.affiliation: Department of Pathology, Instituto Português de Oncologia de Lisboa - Lisboa, Portugal.
authors.forename: Joana Cintia Monteiro
authors.initials: JC
authors.lastname: Ferreira
authors.affiliation: Department of Pathology, Instituto Português de Oncologia de Lisboa - Lisboa, Portugal.
authors.forename: Maria Joaninha Madalena de Palma Mendonça da Costa
authors.initials: MJ
authors.lastname: Rosa
authors.affiliation: Department of Dermatology, Instituto Português de Oncologia de Lisboa - Lisboa, Portugal.
authors.forename: Maria Manuela Antunes Pecegueiro da Silva
authors.initials: MM
authors.lastname: Garcia
mesh_terms: D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009508:Nevus, Pigmented / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*