title: Chronic Blood Pressure Reductions and Increments in Plasma Nitric Oxide Bioavailability.
abstract: This study analyzed the effects of 12 weeks of resistance training (RT) on resting blood pressure (BP) and plasma levels of nitric oxide metabolites (NOx) in pre- and hypertensive older women, and evaluated the relationship between these 2 parameters. Thirty-five older women (68.2±5.7 years, 70.0±14.4 kg, 157.1±6.4 cm, 28.3±5.0 kg.m-2) were randomly allocated into a training group (TG; n=17), which performed a 12-week RT program, and a control group (CG; n=18), which did not perform any physical exercise. Anthropometry, one repetition maximum (1RM), body composition analysis by dual energy X-ray absorptiometry, blood samples, and resting BP were measured. There was a significant interaction for all variables analyzed, in which reductions of systolic BP (-8.5%), diastolic BP (-8.4%), and mean arterial pressure (-8.5%), and increases of NOx (+35.2%) were observed only for the TG. Moreover, a negative and significant correlation was observed (P<0.05; r=-0.63) between NOx and systolic BP in the TG. Results suggest that a 12-week RT program is sufficient to induce reductions in BP in pre- and hypertensive older women and that the decrease in systolic BP is associated with an increase in plasma NOx concentration.
authors.affiliation: Physical Education, Universidade Estadual State University de Londrina, Londrina, Brazil.
authors.forename: Crisieli M
authors.initials: CM
authors.lastname: Tomeleri
authors.affiliation: Physical Education, Universidade Estadual State University de Londrina, Londrina, Brazil.
authors.forename: Alexandre J
authors.initials: AJ
authors.lastname: Marcori
authors.affiliation: Physical Education and Sport Center, Londrina State University, Jataizinho, Brazil.
authors.forename: Alex Silva
authors.initials: AS
authors.lastname: Ribeiro
authors.affiliation: Physical Education Department, Santa Catarina Federal University, Florianópolis, Brazil.
authors.forename: Aline Mendes
authors.initials: AM
authors.lastname: Gerage
authors.affiliation: Physical Education, Universidade Estadual State University de Londrina, Londrina, Brazil.
authors.forename: Camila de Souza
authors.initials: CS
authors.lastname: Padilha
authors.affiliation: Physical Education, Universidade Estadual State University de Londrina, Londrina, Brazil.
authors.forename: Durcelina
authors.initials: D
authors.lastname: Schiavoni
authors.affiliation: Physical Education, Universidade Estadual State University de Londrina, Londrina, Brazil.
authors.forename: Mariana F
authors.initials: MF
authors.lastname: Souza
authors.affiliation: Exercise Science, Kirksville, Truman State University, United States.
authors.forename: Jerry L
authors.initials: JL
authors.lastname: Mayhew
authors.affiliation: Paraná State University - UNESPAR, Paranavaí campus, Paranavaí, Brazil.
authors.forename: Matheus Amarante
authors.initials: MA
authors.lastname: do Nascimento
authors.affiliation: Pathology and Clinical Analisys, Universidade Estadual de Londrina, Londrina, Brazil.
authors.forename: Danielle
authors.initials: D
authors.lastname: Venturini
authors.affiliation: Physical Education, Universidade Estadual State University de Londrina, Londrina, Brazil.
authors.forename: Decio Sabbatini
authors.initials: DS
authors.lastname: Barbosa
authors.affiliation: Physical Education, Londrina State University, Londrina, Brazil.
authors.forename: Edilson Serpeloni
authors.initials: ES
authors.lastname: Cyrino
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D000886:Anthropometry; D001682:Biological Availability; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000628:therapy*; D008875:Middle Aged; D009569:Nitric Oxide / Q000097:blood*; D055070:Resistance Training
chemical_list: D009569:Nitric Oxide