title: Case of primary bilateral diffuse large B-cell lymphoma of the ovary with plasmablastic features in an HIV-negative female patient.
abstract: A 37-year-old woman from Puerto Rico presented to our clinic with symptoms of an abdominal distension progressively worsening over 1 year. A CT of an abdomen and pelvis with contrast was performed and revealed bilateral large heterogeneous pelvic adnexal masses with large ascites and right pleural effusion. Tumour markers CA 125 was 766 U/mL and lactate dehydrogenase was 654 U/L. She underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy with pelvic lymph node dissection and partial omentectomy. Pathology of ovarian masses revealed a diffuse large B-cell lymphoma. The staging work-up was negative, which pointed towards the diagnosis of primary ovarian lymphoma. The patient completed 8 cycles of cyclophosphamide, doxorubicin, vincristine, prednisolone chemotherapy. After 18 months of chemotherapy completion, she remains in remission.
authors.affiliation: Department of Medicine, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA.
authors.forename: Suvarna L
authors.initials: SL
authors.lastname: Guvvala
authors.affiliation: Department of Medicine, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA.
authors.forename: Sailaja
authors.initials: S
authors.lastname: Sakam
authors.affiliation: Department of Pathology, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA.
authors.forename: Masooma
authors.initials: M
authors.lastname: Niazi
authors.affiliation: Department of Medicine, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA.|Division of Hematology and Oncology, Bronx Lebanon Hospital Center, Icahn School of Medicine, Bronx, New York, USA.
authors.forename: Yevgeniy
authors.initials: Y
authors.lastname: Skaradinskiy
mesh_terms: D000328:Adult; D005260:Female; D018023:HIV Seronegativity; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000473:pathology* / Q000628:therapy; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000628:therapy