title: Electronic Nose Technology in Respiratory Diseases.
abstract: Electronic noses (e-noses) are based on arrays of different sensor types that respond to specific features of an odorant molecule, mostly volatile organic compounds (VOCs). Differently from gas chromatography and mass spectrometry, e-noses can distinguish VOCs spectrum by pattern recognition. E-nose technology has successfully been used in commercial applications, including military, environmental, and food industry. Human-exhaled breath contains a mixture of over 3000 VOCs, which offers the postulate that e-nose technology can have medical applications. Based on the above hypothesis, an increasing number of studies have shown that breath profiling by e-nose could play a role in the diagnosis and/or screening of various respiratory and systemic diseases. The aim of the present study was to review the principal literature on the application of e-nose technology in respiratory diseases.
authors.affiliation: Department of Respiratory Diseases, University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy. silvano.dragonieri@uniba.it.
authors.forename: Silvano
authors.initials: S
authors.lastname: Dragonieri
authors.affiliation: Unit of Electronics for Sensor Systems, Center for Integrated Research, Campus Bio-Medico University, Rome, Italy.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Pennazza
authors.affiliation: Department of Respiratory Diseases, University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy.
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Carratu
authors.affiliation: Department of Respiratory Diseases, University of Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy.
authors.forename: Onofrio
authors.initials: O
authors.lastname: Resta
mesh_terms: D001249:Asthma / Q000175:diagnosis*; D001944:Breath Tests; D062609:Electronic Nose; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D008654:Mesothelioma / Q000175:diagnosis; D010997:Pleural Neoplasms / Q000175:diagnosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis*; D012141:Respiratory Tract Infections / Q000175:diagnosis*; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis; D055549:Volatile Organic Compounds / Q000032:analysis*
chemical_list: D055549:Volatile Organic Compounds
keywords: Electronic nose; Exhaled breath; Volatile organic compounds