title: Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial.
abstract: OBJECTIVE
  To determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes.
  
  
  METHODS
  Multicenter, randomized clinical trial.
  
  
  METHODS
  University teaching hospitals.
  
  
  METHODS
  Women aged >18 years with suspected endometriosis who elected to undergo surgical management.
  
  
  METHODS
  Randomization to conventional or robot-assisted laparoscopic removal of endometriosis.
  
  
  METHODS
  The primary outcome measured was operative time. Secondary outcomes were perioperative complications and quality of life.
  
  
  RESULTS
  The mean operative time for robotic vs. laparoscopic surgery for endometriosis was 106.6 ± 48.4 minutes vs. 101.6 ± 63.2 minutes. There were no differences in blood loss, intraoperative or postoperative complications, or rates of conversion to laparotomy in the two arms. Both groups reported significant improvement on condition-specific quality of life outcomes at 6 weeks and 6 months.
  
  
  CONCLUSIONS
  There were no differences in perioperative outcomes between robotic and conventional laparoscopy.
  
  
  BACKGROUND
  NCT01556204.
authors.affiliation: Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio; South Florida Institute for Reproductive Medicine, Miami, Florida; Department of Obstetrics and Gynecology, Herbert Wertheim College of Medicine at Florida International University, Miami, Florida.
authors.forename: Enrique
authors.initials: E
authors.lastname: Soto
authors.affiliation: Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Thanh Ha
authors.initials: TH
authors.lastname: Luu
authors.affiliation: Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Gynecology, Mayo Clinic Arizona, Scottsdale, Arizona.
authors.forename: Javier F
authors.initials: JF
authors.lastname: Magrina
authors.affiliation: Department of Gynecology, Mayo Clinic Arizona, Scottsdale, Arizona.
authors.forename: Megan N
authors.initials: MN
authors.lastname: Wasson
authors.affiliation: Department of Minimally Invasive Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.
authors.forename: Jon I
authors.initials: JI
authors.lastname: Einarsson
authors.affiliation: Department of Minimally Invasive Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Cohen
authors.affiliation: Obstetrics, Gynecology and Women's Health Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: falcont@ccf.org.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Falcone
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D061887:Conversion to Open Surgery; D004715:Endometriosis / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects; D061646:Operative Time; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D011788:Quality of Life; D065287:Robotic Surgical Procedures / Q000009:adverse effects; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States
keywords: Endometriosis; laparoscopy; perioperative outcomes; quality of life; robot-assisted surgery