title: Obstructive sleep apnea-hypopnea syndrome in patients with severe chronic respiratory insufficiency.
abstract: OBJECTIVE
  Although sleep disordered breathing is common in patients with a severe chronic respiratory insufficiency (SCRI), there is few information on its prevalence. Our aim was to describe the prevalence and characteristics of the obstructive sleep apnea-hypopnea syndrome (OSAHS) in these patients.
  
  
  METHODS
  Prospective and observational study carried out on patients with a SCRI included in a waiting list for a lung transplantation and who had undergone a standard polysomnography.
  
  
  RESULTS
  A total of 105 patients were examined, of which 85 met the study's inclusion criteria. The prevalence of the OSAHS was 24.7%, with 19% of cases being severe. The most common underlying respiratory condition was COPD (62%). The OSAHS was linked to the male gender (P=.002), weight (P=.013), BMI (P=.034) and neck circumference (P=.01). Although most patients experienced symptoms suggestive of an OSAHS, the average score obtained in the Epworth Sleepiness Scale was low.
  
  
  CONCLUSIONS
  We observed a high prevalence of OSAHS in patients with a SCRI but without clinical data suggestive of its diagnosis; hence, we believe that sleep studies should be carried out in these patients given the low pre-test clinical suspicion of the disease.
authors.affiliation: Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, España. Electronic address: anahvoth@gmail.com.
authors.forename: Ana
authors.initials: A
authors.lastname: Hernández Voth
authors.affiliation: Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: Javier
authors.initials: J
authors.lastname: Sayas Catalán
authors.affiliation: Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: Pedro
authors.initials: P
authors.lastname: Benavides Mañas
authors.affiliation: Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: Alicia
authors.initials: A
authors.lastname: de Pablo Gafas
authors.affiliation: Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: Trinidad
authors.initials: T
authors.lastname: Díaz Cambriles
authors.affiliation: Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: Victoria
authors.initials: V
authors.lastname: Villena Garrido
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D015995:Prevalence; D011446:Prospective Studies; D012131:Respiratory Insufficiency / Q000150:complications*; D012307:Risk Factors; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*
keywords: Apnea obstructiva; Hipoxemia; Hypoxemia; Lung transplantation; Sleep apnea; Trasplante pulmonar