title: Iodine-Catalyzed Cross Dehydrogenative Coupling Reaction: Sulfenylation of Enaminones Using Dimethyl Sulfoxide as an Oxidant.
abstract: Synthesis of polyfunctionalized aminothioalkenes has been demonstrated using iodine as a catalyst (30 mol %) and dimethyl sulfoxide as an oxidant under metal-free reaction conditions. This methodology allows a facile sulfenylation of enaminones with a broad range of heterocyclic thiols and thiones using cross dehydrogenative coupling methods. In addition, this strategy is highly practical as it employs inexpensive and readily available iodine and DMSO with a short reaction time. The current methodology is one of the simplest methods and provides a straightforward approach to sulfenylation of enaminones via the cross dehydrogenative coupling method.
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India.
authors.forename: Yogesh
authors.initials: Y
authors.lastname: Siddaraju
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science , Bangalore 560 012, Karnataka, India.
authors.forename: Kandikere Ramaiah
authors.identifier: 0000-0002-8342-1534
authors.initials: KR
authors.lastname: Prabhu