title: Exuberant pyoderma gangrenosum in a patient with autoimmune hepatitis.
abstract: Pyoderma gangrenosum is a rare neutrophilic dermatosis, which usually presents as ulcers with erythematous-violaceous undermined edges and a rough base with purulent or sanguinous exudate. It can be primary or associated with an underlying disease. However, rare cases of its association with autoimmune hepatitis have been described in the literature. Diagnosis is based on a characteristic clinical picture and ruling out other causes of ulcers. This paper aims to discuss the management of corticosteroid therapy and the importance of local treatment. We report a case with torpid evolution, presented with multiple and deep ulcers in a young patient with autoimmune hepatitis, causing pain and significant disability. We observed complete healing of lesions after two months of successful treatment.
authors.affiliation: Department of Dermatology of the Universidade Federal do Rio de Janeiro (UFRJ) - Rio de Janeiro (RJ), Brazil.
authors.forename: Stephanie Galiza
authors.initials: SG
authors.lastname: Dantas
authors.affiliation: Department of Pathology of the Fundação Oswaldo Cruz (Fiocruz) - Rio de Janeiro (RJ), Brazil.
authors.forename: Leonardo Pereira
authors.initials: LP
authors.lastname: Quintella
authors.affiliation: Department of Dermatology of the Universidade Federal do Rio de Janeiro (UFRJ) - Rio de Janeiro (RJ), Brazil.
authors.forename: Nurimar Conceição
authors.initials: NC
authors.lastname: Fernandes
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D005260:Female; D019693:Hepatitis, Autoimmune / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D012720:Severity of Illness Index
chemical_list: D000305:Adrenal Cortex Hormones; D011241:Prednisone