title: Top-Down Proteomics and Farm Animal and Aquatic Sciences.
abstract: Proteomics is a field of growing importance in animal and aquatic sciences. Similar to other proteomic approaches, top-down proteomics is slowly making its way within the vast array of proteomic approaches that researchers have access to. This opinion and mini-review article is dedicated to top-down proteomics and how its use can be of importance to animal and aquatic sciences. Herein, we include an overview of the principles of top-down proteomics and how it differs regarding other more commonly used proteomic methods, especially bottom-up proteomics. In addition, we provide relevant sections on how the approach was or can be used as a research tool and conclude with our opinions of future use in animal and aquatic sciences.
authors.affiliation: CIIMAR-Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal. acampos@ciimar.up.pt.
authors.forename: Alexandre M O
authors.initials: AM
authors.lastname: Campos
authors.affiliation: Clinical Department, RUSVM-Ross University School of Veterinary Medicine, PO Box 334, Basseterre, Saint Kitts and Nevis. adealmeida@rossved.edu.kn.
authors.forename: André M
authors.initials: AM
authors.lastname: de Almeida
keywords: aquatic sciences proteomics; farm animal proteomics; top-down proteomics