title: The use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillofacial trauma.
abstract: In recent years, recombinant human bone morphogenetic protein-2 (rhBMP-2) has been introduced as a therapeutic option in the treatment of several congenital and acquired craniofacial defects. Although there have been promising clinical results, the international literature still lacks complete guidelines, including limits and indications for the use of rhBMP-2. The possible indications for rhBMP-2 in patients undergoing facial trauma are discussed in this article.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Loma Linda University, Loma Linda, CA, USA. Electronic address: aherford@llu.edu.
authors.forename: A S
authors.initials: AS
authors.lastname: Herford
mesh_terms: D055396:Bone Morphogenetic Protein 2 / Q000627:therapeutic use*; D006801:Humans; D008446:Maxillofacial Injuries / Q000188:drug therapy* / Q000601:surgery; D011994:Recombinant Proteins / Q000627:therapeutic use; D013515:Surgery, Oral; D023822:Tissue Engineering; D016212:Transforming Growth Factor beta / Q000627:therapeutic use*
chemical_list: D055396:Bone Morphogenetic Protein 2; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; C499469:recombinant human bone morphogenetic protein-2
keywords: Clinical application; Maxillofacial trauma; Recombinant human bone morphogenetic protein-2