title: The diagnostic value of contrast-enhanced computed tomography imaging for detection of colorectal tumors: A meta-analysis.
abstract: OBJECTIVE
  To evaluate the application usage of contrast-enhanced computer tomography imaging for colorectal tumors diagnosis.
  
  
  METHODS
  By searching the Medline and CNKI databases, we collected all diagnostic tests about contrast-enhanced CT imaging for colorectal tumors. Sensitivity and specificity were calculated to evaluate the usage of individual diagnostic tests. The data were analyzed using statistic software Meta-DiSc 1.4.
  
  
  RESULTS
  Nine trials that included a total of 4797 patients were analyzed in this study. The summary diagnosis sensitivity and specificity of contrast-enhanced CT were 0.74 (95% confidence interval [CI]: 0.71-0.77) and 0.86 (0.85-0.87), respectively. The pooled area under the receiver operating characteristic curve was 0.90. Subgroup analysis: for intravenous contrast enhancement technology, the pooled diagnosis sensitivity and specificity were 0.63 (95% CI: 0.56-0.69) and 0.89 (95% CI: 0.86-0.92); for oral contrast enhancement technology, the pooled diagnosis sensitivity and specificity were 0.78 (95% CI: 0.74-0.81) and 0.86 (95% CI: 0.84-0.87).
  
  
  CONCLUSIONS
  Contrast-enhanced CT imaging can be regarded as an effective and feasible method for detection of the colorectal tumors.
authors.affiliation: Department of Radiology, Huaihe Hospital of Henan University, Kaifeng 475001, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Yu
authors.affiliation: Department of Radiology, Huaihe Hospital of Henan University, Kaifeng 475001, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Liu
mesh_terms: D015179:Colorectal Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D006801:Humans; D012372:ROC Curve; D011856:Radiographic Image Enhancement; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media