title: Characteristics and Prognosis of Pacemaker-Identified New-Onset Atrial Fibrillation in Japanese People.
abstract: The characteristics and prognosis of implanted pacemaker-identified new-onset atrial fibrillation (AF) in Japanese people has not been well evaluated.
  
  
  
  A total of 395 consecutive patients with newly implanted pacemakers were retrospectively analyzed between January 2010 and December 2015 at Yokohama City University Hospital. Patients with a prior history of AF, VVI mode pacemaker, congenital heart disease, severe valvular heart disease, and cardiovascular surgery before pacemaker implantation were excluded. Among the remaining patients, 44 (21.3%) developed new AF during follow-up (mean follow-up, 1,115±651 days; range, 9-2,176 days). Patients with new-onset AF had a significantly higher CHADS2score (2.09±1.27 vs. 1.31±1.08, P<0.001) and CHA2DS2-VASc score (3.00±1.39 vs. 2.26±1.19, P<0.001) compared with those without new-onset AF. On Cox regression analysis only age at implantation was significantly correlated with new-onset AF. Interestingly, the incidence of hospitalization due to heart failure was significantly higher in the new-onset AF than in the without new-onset AF group.
  
  
  
  A total of 21.3% of pacemaker-implanted patients with high CHADS2and CHA2DS2-VASc scores developed new-onset AF during a mean follow-up of 3.1 years; and pacemaker-identified AF was associated with an increased risk of worsening heart failure.
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Ogino
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Ishikawa
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Ishigami
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Katsumi
authors.initials: K
authors.lastname: Matsumoto
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Junya
authors.initials: J
authors.lastname: Hosoda
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Kouhei
authors.initials: K
authors.lastname: Iguchi
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Hirooki
authors.initials: H
authors.lastname: Matsushita
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Taguchi
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Horiguchi
authors.affiliation: Department of Cardiology, Yokohama City University Hospital.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kimura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000453:epidemiology / Q000628:therapy; D006333:Heart Failure / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D006349:Heart Valve Diseases / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D015994:Incidence; D007564:Japan; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D011379:Prognosis
keywords: Aging; Atrial fibrillation; CHA2DS2-VASc score; CHADS2 score; Pacemaker