title: Impact of type 2 diabetes on cardiorespiratory function and exercise performance.
abstract: The aim of this study was to examine the impact of well-controlled uncomplicated type 2 diabetes (T2D) on exercise performance. Ten obese sedentary men with T2D and nine control participants without diabetes matched for age, sex, and body mass index were recruited. Anthropometric characteristics, blood samples, resting cardiac, and pulmonary functions and maximal oxygen uptake (VO2max) and ventilatory threshold were measured on a first visit. On the four subsequent visits, participants (diabetics:n= 6; controls:n= 7) performed step transitions (6 min) of moderate-intensity exercise on an upright cycle ergometer from unloaded pedaling to 80% of ventilatory threshold.VO2(τVO2) and HR (τHR) kinetics were characterized with a mono-exponential model.VO2max(27.0 ± 3.4 vs. 26.7 ± 5.0 mL kg-1min-1;P= 0.85),τVO2(43 ± 6 vs. 43 ± 10 sec;P= 0.73), andτHR (42 ± 17 vs. 43 ± 13 sec;P= 0.94) were similar between diabetics and controls respectively. The remaining variables were also similar between groups, with the exception of lower maximal systolic blood pressure in diabetics (P= 0.047). These results suggest that well-controlled T2D is not associated with a reduction inVO2maxor slowerτVO2andτHR.
authors.affiliation: Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Québec, Canada.|Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.
authors.forename: Joanie
authors.initials: J
authors.lastname: Caron
authors.affiliation: School of Health & Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
authors.forename: Gregory R
authors.initials: GR
authors.lastname: duManoir
authors.affiliation: Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Québec, Canada.|Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.
authors.forename: Lawrence
authors.initials: L
authors.lastname: Labrecque
authors.affiliation: Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Québec, Canada.|Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.
authors.forename: Audrey
authors.initials: A
authors.lastname: Chouinard
authors.affiliation: Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.
authors.forename: Annie
authors.initials: A
authors.lastname: Ferland
authors.affiliation: Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.|Faculty of Pharmacy, Université Laval, Québec, Québec, Canada.
authors.forename: Paul
authors.initials: P
authors.lastname: Poirier
authors.affiliation: Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Legault
authors.affiliation: Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Québec, Canada Patrice.brassard@kin.ulaval.ca.|Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.
authors.forename: Patrice
authors.initials: P
authors.lastname: Brassard
mesh_terms: D054874:Athletic Performance / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D017079:Exercise Tolerance / Q000502:physiology; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000503:physiopathology; D010101:Oxygen Consumption / Q000502:physiology*
keywords: Heart rate kinetics; maximal oxygen uptake; oxygen uptake kinetics; type 2 diabetes