title: Risk Factors for Abdominal Aortic Aneurysm in the Korean Population.
abstract: BACKGROUND
  Ultrasound screening shows a clinical benefit in reducing abdominal aortic aneurysm (AAA)-related mortality. However, its cost-effectiveness remains unclear. Understanding the relationship between risk factors and AAA is important to maximize the benefit of AAA screening. However, risk factors for AAA have not been reported in Korea. The purpose of this study is to determine the prevalence of, and risk factors for, AAA among the Korean population.
  
  
  METHODS
  The study population consisted of patients >50 years of age who consented for AAA screening. Screening was performed as follows for all participants: collection of demographic information, including risk factors, physical examination, and ultrasound screening. We measured the maximal diameter of the aorta from the outer to outer layer at 5 levels: suprarenal, renal, and infrarenal aorta, and bilateral common iliac arteries. AAA was defined as maximal aortic diameter >3 cm. The risk factors and risk ratio for AAA were determined. Chi-square test and a logistic regression model were used for statistical analysis. All P-values <0.05 were considered significant.
  
  
  RESULTS
  A total of 2,035 participants were enrolled. Among them, 908 (44.6%) were men and 1,127 (55.4%) were women. Mean age was 66.9 ± 10.3 years (range 23-95). AAA was detected in 18 of 908 (2.0%) men and 4 of 1,127 (0.4%) women. The presence of an AAA was significantly correlated with male sex (P < 0.001), advanced age (P = 0.01), smoking (P < 0.001), alcohol consumption (P < 0.01), and the presence of pulmonary disease (P = 0.01). Multivariate analysis revealed that smoking was the only significant risk factor for AAA.
  
  
  CONCLUSIONS
  The prevalence of AAA was 2.0% in men and 0.4% in women. Male sex, old age, smoking, alcohol use, and pulmonary disease are possible risk factors for AAA in the general Korean population. Smoking is the strongest risk factor for the development of AAA.
authors.affiliation: Department of Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
authors.forename: Sang-Ah
authors.initials: SA
authors.lastname: Han
authors.affiliation: Department of Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea. Electronic address: jhjoh@khu.ac.kr.
authors.forename: Jin Hyun
authors.initials: JH
authors.lastname: Joh
authors.affiliation: Department of Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
authors.forename: Ho-Chul
authors.initials: HC
authors.lastname: Park
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000453:epidemiology*; D016009:Chi-Square Distribution; D015897:Comorbidity; D004108:Dilatation, Pathologic; D005260:Female; D006801:Humans; D016015:Logistic Models; D008171:Lung Diseases / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D011237:Predictive Value of Tests; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D014463:Ultrasonography; D055815:Young Adult