title: CuBr/TBHP-mediated synthesis of N-acyl sulfonimidamides via the oxidative cross-coupling of sulfonimidamides and aldehydes.
abstract: N-Acyl sulfonimidamides were synthesized via a Cu-catalyzed double C-H/N-H activation protocol. The imino end of sulfonimidamides was acylated using aldehyde as the acylating agent and t-butyl hydrogen peroxide (TBHP) as the oxidant in acetonitrile (MeCN) at 82 °C. The mild reaction conditions afforded low-to-moderate yields of N-acyl sulfonimidamides with high structural diversity.
authors.affiliation: Organic Chemistry Section, Chemical Science and Technology Division, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum, India. ganeshnandi@gmail.com.
authors.forename: Ganesh Chandra
authors.identifier: http://orcid.org/0000-0003-2159-8075
authors.initials: GC
authors.lastname: Nandi
authors.affiliation: Organic Chemistry Section, Chemical Science and Technology Division, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum, India. ganeshnandi@gmail.com.
authors.forename: Cijil
authors.initials: C
authors.lastname: Raju