title: Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report.
abstract: BACKGROUND
  Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. Early detection and institution of anti-tuberculosis medications can be life-saving.
  
  
  METHODS
  A 23-year-old Bengali man presented with prolonged fever, weight loss, hepatosplenomegaly, pancytopenia and altered liver function. He had high erythrocyte sedimentation rate, positive tuberculin test, granuloma in liver biopsy, and haemophagocytosis was evidenced by histopathological examination of bone marrow. He recovered with anti-tuberculosis therapy.
  
  
  CONCLUSIONS
  This case demonstrates that consideration of tuberculosis as an underlying cause of haemophagocytic syndrome could be rewarding and life-saving in this rapidly fatal condition.
authors.affiliation: Department of Nephrology and Dialysis, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, 1000, Bangladesh. wmmhaque@live.com.
authors.forename: Wasim Md Mohosin Ul
authors.initials: WM
authors.lastname: Haque
authors.affiliation: Department of Nephrology and Dialysis, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, 1000, Bangladesh.
authors.forename: Md Erfanur Rahman
authors.initials: ME
authors.lastname: Shuvo
authors.affiliation: Department of Nephrology and Dialysis, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, 1000, Bangladesh.
authors.forename: Muhammad Abdur
authors.initials: MA
authors.lastname: Rahim
authors.affiliation: Department of Nephrology and Dialysis, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, 1000, Bangladesh.
authors.forename: Palash
authors.initials: P
authors.lastname: Mitra
authors.affiliation: Department of Nephrology and Dialysis, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, 1000, Bangladesh.
authors.forename: Tabassum
authors.initials: T
authors.lastname: Samad
authors.affiliation: Ibrahim Medical College, Shahbag, Dhaka, 1000, Bangladesh.
authors.forename: Jalaluddin Ashraful
authors.initials: JA
authors.lastname: Haque
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005335:Fever of Unknown Origin / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000209:etiology* / Q000517:prevention & control; D008297:Male; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents
keywords: Case report; Haemophagocytic syndrome; Pyrexia of unknown origin; Tuberculosis