title: Case report: Neuromuscular block induced by rocuronium following sugammadex administration.
abstract: We present a case in which rocuronium was applied for muscle relaxation following the administration of sugammadex. An emergency surgery under general anesthesia was planned for a 43-year-old male patient due to an L1 vertebral corpus and right tibia-fibula shaft fracture. Anesthesia was induced with fentanyl, propofol and lidocaine. After applying only 30mg of the total induction dose of rocuronium, it was learned that the neurological examination should be controlled again from the surgeon because of the controversial of the neurological deficit. As a result, patient awakened from anesthesia. We administered 2mg/kg sugammadex and spontaneous breathing of patient returned immediately. The patient became conscious and orientated immediately afterwards. The neurological examination of the lower extremities was performed. The patient was anesthetized once again and 0.6mg/kg rocuronium was given in order to gain neoromuscular block approximately 10min after sugammadex administration. 2min later, the patient was smoothly intubated. Neuromuscular monitorization was not used because of emergency. We administered 2mg/kg sugammadex at the end of the procedure and the patient was extubated. The most suitable time for the re-establishment of rocuronium following sugammadex is currently unclear. This case showed that neuromuscular block can be effectively re-induced by rocuronium following the reversal of rocuronium-induced neuromuscular block with sugammadex. In this case, we consider that the ability to effectively reuse normal induction doses of rocuronium is an important clinical observation.
authors.affiliation: Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey. Electronic address: dr.tugba.askin@gmail.com.
authors.forename: Tugba
authors.initials: T
authors.lastname: Askin
authors.affiliation: Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey.
authors.forename: Suheyla
authors.initials: S
authors.lastname: Unver
authors.affiliation: Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Oguz
authors.affiliation: Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey.
authors.forename: Kubra
authors.initials: K
authors.lastname: Kutay
mesh_terms: D000058:Accidental Falls; D000328:Adult; D000732:Androstanols / Q000008:administration & dosage*; D000768:Anesthesia, General; D006801:Humans; D058926:Intraoperative Awareness / Q000188:drug therapy; D008159:Lumbar Vertebrae / Q000293:injuries; D008297:Male; D009126:Muscle Relaxation / Q000187:drug effects*; D019148:Neuromuscular Blockade / Q000379:methods*; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage*; D000077123:Rocuronium; D016103:Spinal Fractures / Q000209:etiology / Q000601:surgery; D000077122:Sugammadex; D013978:Tibial Fractures / Q000209:etiology / Q000601:surgery; D047408:gamma-Cyclodextrins / Q000008:administration & dosage*
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium
keywords: Neuromuscular block; Rocuronium; Sugammadex