title: An unexpected use of ferrocene. A scanning electrochemical microscopy study of a toll-like receptor array and its interaction with E. coli.
abstract: Imaging of toll-like receptor microarrays was achieved using scanning electrochemical microscopy with the successful integration of two ferrocene derivatives in order to enhance the background contrast. This investigation has resulted in the novel fabrication of a tuneable, multiplex, broad-spectrum bacterial sensor for the interrogation of conserved microbial stimuli.
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON M1C 1A4, Canada. bernie.kraatz@utoronto.ca and Department of Chemistry and Chemical Engineering, Royal Military College of Canada, PO Box 17000, Station Forces, Kingston, ON K7K 7B4, Canada.
authors.forename: Zhe
authors.initials: Z
authors.lastname: She
authors.affiliation: Department of Chemistry and Chemical Engineering, Royal Military College of Canada, PO Box 17000, Station Forces, Kingston, ON K7K 7B4, Canada.
authors.forename: Kristin
authors.initials: K
authors.lastname: Topping
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON M1C 1A4, Canada. bernie.kraatz@utoronto.ca and Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing, 100083, P. R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Dong
authors.affiliation: Department of Chemistry, 80. St. George Street, Toronto, M5S 3H6, Canada and Department of Chemistry and Biochemistry, Southern Illinois University Carbondale Neckers, 4409, 1245 Lincoln Drive, Carbondale, IL 62901, USA.
authors.forename: Mohtashim H
authors.initials: MH
authors.lastname: Shamsi
authors.affiliation: Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON M1C 1A4, Canada. bernie.kraatz@utoronto.ca and Department of Chemistry and Chemical Engineering, Royal Military College of Canada, PO Box 17000, Station Forces, Kingston, ON K7K 7B4, Canada and Department of Chemistry, 80. St. George Street, Toronto, M5S 3H6, Canada.
authors.forename: Heinz-Bernhard
authors.identifier: http://orcid.org/0000-0002-7149-0110
authors.initials: HB
authors.lastname: Kraatz
mesh_terms: D015374:Biosensing Techniques; D055664:Electrochemical Techniques; D004926:Escherichia coli / Q000737:chemistry*; D005296:Ferrous Compounds / Q000737:chemistry*; D000075163:Metallocenes / Q000737:chemistry*; D040081:Protein Array Analysis; D051193:Toll-Like Receptors / Q000032:analysis* / Q000737:chemistry*
chemical_list: D005296:Ferrous Compounds; D000075163:Metallocenes; D051193:Toll-Like Receptors; C004998:ferrocene