title: Novel biomarkers for patients with idiopathic acute anterior uveitis: neutrophil to lymphocyte ratio and platelet to lymphocyte ratio.
abstract: OBJECTIVE
  To assess the levels of the neutrophil to lymphocyte ratio (N/L) and the platelet to lymphocyte ratio (P/L) in patients with idiopathic acute anterior uveitis (AAU) and to compare with healthy controls.
  
  
  METHODS
  Thirty-six male patients with idiopathic AAU and 36 male healthy subjects were enrolled in this retrospective study. Complete ophthalmological examination and complete blood count measurements results of all subjects were evaluated.
  
  
  RESULTS
  There was a significant difference in N/L and P/L between idiopathic AAU and control groups (P=0.006,P=0.022). Also, correlation analysis revealed a significant correlation between C-reactive protein (CRP) and N/L (P=0.002;r=0.461).
  
  
  CONCLUSIONS
  Our study for the first time provides evidence of N/L and P/L may be useful biomarkers in patients with idiopathic AAU. N/L is correlated with CRP, so it can be a useful biomarker to predict the prognosis in idiopathic AAU.
authors.affiliation: Kellogg Eye Center, University of Michigan, Ann Arbor, MI 48105, USA.
authors.forename: Cem
authors.initials: C
authors.lastname: Ozgonul
authors.affiliation: Department of Biochemistry, Gulhane Military Medical Academy, Haydarpasa Training Hospital, Istanbul 34512, Turkey.
authors.forename: Erdim
authors.initials: E
authors.lastname: Sertoglu
authors.affiliation: Department of Ophthalmology, Gulhane Military Medical Academy, Ankara 06065, Turkey.
authors.forename: Onder
authors.initials: O
authors.lastname: Ayyildiz
authors.affiliation: Department of Ophthalmology, Gulhane Military Medical Academy, Ankara 06065, Turkey.
authors.forename: Tarkan
authors.initials: T
authors.lastname: Mumcuoglu
authors.affiliation: Department of Ophthalmology, Gulhane Military Medical Academy, Ankara 06065, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Kucukevcilioglu
authors.affiliation: Department of Ophthalmology, Gulhane Military Medical Academy, Ankara 06065, Turkey.
authors.forename: Gokcen
authors.initials: G
authors.lastname: Gokce
authors.affiliation: Department of Ophthalmology, Gulhane Military Medical Academy, Ankara 06065, Turkey.
authors.forename: Ali Hakan
authors.initials: AH
authors.lastname: Durukan
keywords: C-reactive protein; inflammation; lymphocyte; neutrophil; platelet; uveitis