title: Rhodamine Diaminomaleonitrile Conjugate as a Novel Colorimetric Fluorescent Sensor for Recognition of Cd2+Ion.
abstract: Rhodamine diaminomaleonitrile linked probe (RD-1) shows highly sensitive colorimetric and selective turn-on fluorescent response to Cd2+over other metal ions. The fluorescence intensity and absorbance of the probe RD-1 showed a good linearity, with very low detection limits of 18.5 nm. The probe RD-1 was preliminarily applied to the determination of Cd2+ion in water samples from river and tap water with satisfying results. The live cell image confocal microscopy, HeLa cell demonstrated that RD-1 had low cytotoxicity with good membrane permeable property is successfully applied to fluorescence microscopic imaging for the detection of Cd2+ions.
authors.affiliation: Department of Chemistry, Anna University - University College of Engineering, Dindigul, 624622, India.
authors.forename: Perumal
authors.initials: P
authors.lastname: Sakthivel
authors.affiliation: Department of Chemistry, Anna University - University College of Engineering, Dindigul, 624622, India. karuppannansekar@gmail.com.
authors.forename: Karuppannan
authors.initials: K
authors.lastname: Sekar
authors.affiliation: Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, 560065, India.
authors.forename: Gandhi
authors.initials: G
authors.lastname: Sivaraman
authors.affiliation: Department of Chemistry, SSM Institute of Engineering and Technology, Dindigul, 624002, India. vesp1984@gmail.com.
authors.forename: Subramanian
authors.initials: S
authors.lastname: Singaravadivel
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002104:Cadmium / Q000032:analysis*; D002470:Cell Survival; D003124:Colorimetry / Q000379:methods*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D057230:Limit of Detection; D018613:Microscopy, Confocal; D009570:Nitriles / Q000737:chemistry*; D061848:Optical Imaging / Q000379:methods; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes; D009570:Nitriles; D012235:Rhodamines; D002104:Cadmium; C022103:diaminomaleonitrile
keywords: Cadmium; Diaminomaleonitrile; Fluorescence; Rhodamine; Sensor