title: [Litholytic therapy for urate nephrolithiasis].
abstract: OBJECTIVE
  To evaluate the effectiveness of ESWL combined with litholytic therapy in patients with uric acid kidney stones.
  
  
  METHODS
  A total of 59 patients with urate nephrolithiasis were observed at the Department of Urology, First Pavlov SMU of St. Peterburg. The patients were divided into two groups according to the treatment regimen. The study group comprised 30 patients who were administered litholytic therapy before ESWL. The comparison group included 29 patients with nephrolithiasis who underwent ESWL without prior litholytic therapy.
  
  
  RESULTS
  After 4 weeks of treatment with Blemaren, in 60% of patients of the study group a decrease in the calculus size was noted; in 83.3% of patients according to MSCT there was a decrease in calculus density. Disintegration of kidney stones after a single ESWL session was achieved in 86.7% of patients of the study group and in 65.5% of patients of the control group.
  
  
  CONCLUSIONS
  The results of this study allow us to recommend a 4-week course of Blemaren to treat patients with urate nephrolithiasis to prepare for ESWL.
authors.affiliation: Department of Urology First Pavlov State Medical University of St. Peterburg.|Department of Urology, Research Institute of Surgery and Emergency Medicine, First Pavlov State Medical University of St. Peterburg.
authors.forename: S Kh
authors.initials: SK
authors.lastname: Al'-Shukri
authors.affiliation: Department of Urology, Research Institute of Surgery and Emergency Medicine, First Pavlov State Medical University of St. Peterburg.
authors.forename: M N
authors.initials: MN
authors.lastname: Slesarevskaya
authors.affiliation: Department of Urology First Pavlov State Medical University of St. Peterburg.|Department of Urology, Research Institute of Surgery and Emergency Medicine, First Pavlov State Medical University of St. Peterburg.
authors.forename: I V
authors.initials: IV
authors.lastname: Kuz'min
mesh_terms: D000328:Adult; D000368:Aged; D019343:Citric Acid / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008096:Lithotripsy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D053040:Nephrolithiasis / Q000628:therapy*; D014527:Uric Acid
chemical_list: D014527:Uric Acid; D019343:Citric Acid
keywords: Blemaren; citrate therapy; kidney stone; litholysis; urate nephrolithiasis