title: Penile squamous cell carcinoma: a review of the literature and case report treated with Mohs micrographic surgery.
abstract: The majority of penile carcinoma is squamous cell carcinoma. Although uncommon in the United States, it represents a larger proportion of cancers in the underdeveloped world. Invasive squamous cell carcinoma may arise from precursor lesions or de novo , and has been associated with lack of circumcision and HPV infection. Early diagnosis is imperative as lymphatic spread is associated with a poor prognosis. Radical surgical treatment is no longer the mainstay, and penile sparing treatments now are often used, including Mohs micrographic surgery. Therapeutic decisions should be made with regard to the size and location of the tumor, as well as the functional desires of the patient. It is critical for the dermatologist to be familiar with the evaluation, grading/staging, and treatment advances of penile squamous cell carcinoma. Herein, we present a review of the literature regarding penile squamous cell carcinoma, as well as a case report of invasive squamous cell carcinoma treated with Mohs micrographic surgery.
authors.affiliation: School of medicine - University of Nevada - Reno, United States.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Marchionne
authors.affiliation: School of medicine - University of Nevada - Reno, United States.
authors.forename: Caroline
authors.initials: C
authors.lastname: Perez
authors.affiliation: Department of Dermatology - State University of New York - Downstate and Veterans Affairs Medical Center - Brooklyn (NY), United States.
authors.forename: Andrea
authors.initials: A
authors.lastname: Hui
authors.affiliation: Department of Dermatology - State University of New York - Downstate and Veterans Affairs Medical Center - Brooklyn (NY), United States.
authors.forename: Amor
authors.initials: A
authors.lastname: Khachemoune
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D010412:Penile Neoplasms / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome