title: Where Sepsis and Antimicrobial Resistance Countermeasures Converge.
abstract: The United Nations General Assembly debate on antimicrobial resistance (AMR) recognizes the global significance of AMR. Much work needs to be done on technology capability and capacity to convert the strategic intent of the debate into operational plans and tangible outcomes. Enhancement of the biomedical science-clinician interface requires better exploitation of systems biology tools for in-laboratory and point of care methods that detect sepsis and characterize AMR. These need to link sepsis and AMR data with responsive, real-time surveillance. We propose an AMR sepsis register, similar in concept to a cancer registry, to aid coordination of AMR countermeasures.
authors.affiliation: The Marshall Centre for Infectious Diseases Training and Research, School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia; Department of Microbiology, PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Nedlands, WA, Australia.
authors.forename: Timothy J J
authors.initials: TJ
authors.lastname: Inglis
authors.affiliation: The Marshall Centre for Infectious Diseases Training and Research, School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia; Department of Microbiology, PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Nedlands, WA, Australia.
authors.forename: Nadia
authors.initials: N
authors.lastname: Urosevic
keywords: antimicrobial resistance; biocomplexity; infection control; integrated systems biology; microbial forensics; sepsis