title: The Prevalence of Marfan Syndrome in Korea.
abstract: The aim of this study was to assess the prevalence of Marfan syndrome (MFS) in Korean adults. Data were collected from the National Health Insurance Service in Korea from 2006 through 2013. The data consisted of primary diagnoses related to MFS (Q87.4) diagnosed according to the 10th revision of the International Statistical Classification of Diseases and Related Health Problems. The age-standardized prevalence of MFS in adults was calculated using the estimated Korean population in 2010 as a reference. Overall, the prevalence of MFS was 0.90 per 100,000 persons in 2006 and 2.27 in 2013. For males in 2013, the prevalence per 100,000 persons was 2.61 in overall and 4.32 in 15-19 years-old. For females in 2013, the prevalence per 100,000 persons was 1.92 in overall and 3.02 in 10-14 years-old. In conclusion, currently, the age-standardized overall prevalence of MFS was 2.27 persons per 100,000 persons. And the overall age-standardized prevalence of MFS increased between 2006 and 2013 especially in 15-19 years-old males and 10-14 years-old females.
authors.affiliation: Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Shin Yi
authors.identifier: http://orcid.org/0000-0003-4319-7029
authors.initials: SY
authors.lastname: Jang
authors.affiliation: The National Health Insurance Service, Wonju, Korea.
authors.forename: Su Ra
authors.identifier: http://orcid.org/0000-0002-9118-5682
authors.initials: SR
authors.lastname: Seo
authors.affiliation: Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Seung Woo
authors.identifier: http://orcid.org/0000-0002-2941-515X
authors.initials: SW
authors.lastname: Park
authors.affiliation: Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dukkyung.kim@samsung.com.
authors.forename: Duk Kyung
authors.identifier: http://orcid.org/0000-0001-9227-4196
authors.initials: DK
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008382:Marfan Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D055815:Young Adult
keywords: Marfan Syndrome; Prevalence; Republic of Korea