title: [Spontaneous remission of HCV infection after autologous stem cell transplantation in a 58-year-old man].
abstract: We report about a 58-year-old man with a chronic and treatment-naive hepatitis C virus (HCV) infection of genotype 1b, who had undergone autologous stem cell transplantation twice due to multiple myeloma. Subsequently, a high-level viremic reactivation of an occult hepatitis B virus (HBV) infection and also a reverse seroconversion was observed. Furthermore, a sustained spontaneous remission of HCV infection was seen. Antiviral therapy of HBV infection was initiated with tenofovir. Seven months after therapy initiation, the patient acquired an "anti-HBc-only" status. Antiviral therapy with tenofovir is still continued. The patient is in a good clinical condition.
authors.affiliation: Klinik für Gastroenterologie und gastrointestinale Onkologie, Universitätsmedizin Göttingen, Göttingen, Deutschland. lars.reinhardt@med.uni-goettingen.de.|Leberzentrum Göttingen, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland. lars.reinhardt@med.uni-goettingen.de.
authors.forename: L
authors.initials: L
authors.lastname: Reinhardt
authors.affiliation: Institut für Medizinische Mikrobiologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Eiffert
authors.affiliation: Klinik für Hämatologie und Medizinische Onkologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Wulf
authors.affiliation: Leberzentrum Göttingen, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.|Institut für Pathologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Ströbel
authors.affiliation: Klinik für Gastroenterologie und gastrointestinale Onkologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.|Leberzentrum Göttingen, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.
authors.forename: S C B
authors.initials: SCB
authors.lastname: Bremer
authors.affiliation: Klinik für Gastroenterologie und gastrointestinale Onkologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Amanzada
authors.affiliation: Klinik für Gastroenterologie und gastrointestinale Onkologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.|Leberzentrum Göttingen, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.
authors.forename: V
authors.initials: V
authors.lastname: Ellenrieder
authors.affiliation: Klinik für Gastroenterologie und gastrointestinale Onkologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Neesse
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D016174:Hepacivirus; D006509:Hepatitis B / Q000188:drug therapy* / Q000276:immunology; D006515:Hepatitis B virus / Q000502:physiology*; D006526:Hepatitis C / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000628:therapy*; D012075:Remission, Spontaneous; D033581:Stem Cell Transplantation; D000068698:Tenofovir / Q000627:therapeutic use; D014775:Virus Activation
chemical_list: D000998:Antiviral Agents; D000068698:Tenofovir
keywords: Coinfection; Hepatitis B virus; Multiple myeloma; Seroconversion, reverse; Tenofovir