title: Safety and effectiveness of sleeve gastrectomy versus gastric bypass: one-year results of Tehran Obesity Treatment Study (TOTS).
abstract: OBJECTIVE
  We aimed to compare the effectiveness and safety of sleeve gastrectomy versus gastric bypass at one-year.
  
  
  BACKGROUND
  Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the two most commonly performed bariatric procedures worldwide.
  
  
  METHODS
  Patients from a prospectively collected database who presented to a specialized bariatric center and underwent a primary bariatric procedure between March 2013 and April 2015 were included and compared regarding major and minor complication rates and weight loss parameters at 6 and 12 months.
  
  
  RESULTS
  A total of 513 patients with a mean age of 37.5±12.5, 82.6 % female and mean body mass index (BMI) of 44.1±6.3 kg/m2 were included in our analysis: 73.3% underwent SG and 26.7% underwent RYGB. Major and minor complication rates were 7.1 and 2.6% for SG vs. 9.5 and 2.2% for the RYGB, respectively (P=NS). The operative and anesthesia time in SG patients were significantly shorter than in RYGB patients (P<0.001). SG and RYBG patients achieved similar excess weight loss at one year (75.4±20.5% vs. 71.8±26.3%, respectively,P=NS). Baseline BMI was the only predictive factor for weight loss at one year (OR: 0.901, CI: 0.827-0.982,P<0.017).
  
  
  CONCLUSIONS
  RYGB and SG both showed similar one-year safety and effectiveness. Long-term studies are needed to complement these findings.
authors.affiliation: Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Barzin
authors.affiliation: Faculty of Medicine, Shahed University, Tehran, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Khalaj
authors.affiliation: Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Motamedi
authors.affiliation: Minimally Invasive Surgery Research Center, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Pravin
authors.initials: P
authors.lastname: Shapoori
authors.affiliation: Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Fereidoun
authors.initials: F
authors.lastname: Azizi
authors.affiliation: Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Farhad
authors.initials: F
authors.lastname: Hosseinpanah
keywords: Bariatric surgery; Gastric bypass; Laparoscopy; Morbid obesity; Sleeve gastrectomy