title: Improved photodynamic activities of liposome-incorporated [60]fullerene derivatives bearing a polar group.
abstract: [60]Fullerene (C60) derivatives were incorporated into liposomes using a fullerene exchange method involving the transfer of the fullerene from the cavity of two γ-cyclodextrin molecules to a liposome. A lipid-membrane-incorporated C60derivative bearing a polar group showed much higher photodynamic activity than the analogous system incorporating pristine C60.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima 739-8527, Japan.
authors.forename: Atsushi
authors.identifier: http://orcid.org/0000-0003-3492-3455
authors.initials: A
authors.lastname: Ikeda
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima 739-8527, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Mae
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima 739-8527, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Ueda
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima 739-8527, Japan.
authors.forename: Kouta
authors.initials: K
authors.lastname: Sugikawa
authors.affiliation: Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8530, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Shigeto
authors.affiliation: Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8530, Japan.
authors.forename: Hisakage
authors.initials: H
authors.lastname: Funabashi
authors.affiliation: Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8530, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Kuroda
authors.affiliation: Faculty of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 113-8551, Japan.
authors.forename: Motofusa
authors.initials: M
authors.lastname: Akiyama
mesh_terms: D016923:Cell Death / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D037741:Fullerenes / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D008081:Liposomes; D015394:Molecular Structure; D010778:Photochemotherapy; D047408:gamma-Cyclodextrins / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology
chemical_list: D037741:Fullerenes; D008081:Liposomes; D047408:gamma-Cyclodextrins; C023792:gamma-cyclodextrin; C069837:fullerene C60