title: Checks and Balances: Rpd3 Issues Executive Orders in Developmental Enhancer Regulation.
abstract: Stem cells use poised enhancers of developmental regulators to maintain pluripotency and for subsequent activation in differentiating progeny. In this issue of Developmental Cell, Janssens et al. (2017) demonstrate that the erm enhancer is maintained in a poised state in neural stem cells by the histone deacetylase Hdac1/Rpd3.
authors.affiliation: Green Center for Reproductive Biology Sciences, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
authors.forename: Sara
authors.initials: S
authors.lastname: Martire
authors.affiliation: Green Center for Reproductive Biology Sciences, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: laura.banaszynski@utsouthwestern.edu.
authors.forename: Laura
authors.initials: L
authors.lastname: Banaszynski
mesh_terms: D000107:Acetylation; D004742:Enhancer Elements, Genetic; D056284:Histone Deacetylase 1 / Q000378:metabolism*; D006655:Histone Deacetylases / Q000235:genetics*; D006801:Humans; D058953:Neural Stem Cells / Q000378:metabolism
chemical_list: D056284:Histone Deacetylase 1; D006655:Histone Deacetylases