title: Somatostatin Receptor SPECT/CT using99mTc Labeled HYNIC-TOC Aids in Diagnosis of Primary Optic Nerve Sheath Meningioma.
abstract: Primary optic nerve sheath meningiomas (ONSM) are rare, benign and slow growing tumor involving the intra-orbital/intra-canalicular segment of the optic nerve. Untreated, they can potentially lead to visual deterioration. Magnetic resonance (MR) is the gold standard imaging modality for diagnosing the entity. Often, a clinical dilemma exists to narrow the differential diagnosis of an enhancing intra-orbital mass on MR. Molecular imaging provides a high degree of precision in diagnosing meningioma in view of relatively high levels of somatostatin receptor expression by these tumors. The following case demonstrates the potential clinical utility of somatostatin receptor SPECT using99mTc- labeled HYNIC-TOC in clinical diagnosis of ONSM.
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.
authors.forename: Piyush
authors.initials: P
authors.lastname: Chandra
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.
authors.forename: Nilendu
authors.initials: N
authors.lastname: Purandare
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.
authors.forename: Sneha
authors.initials: S
authors.lastname: Shah
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.
authors.forename: Archi
authors.initials: A
authors.lastname: Agrawal
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.
authors.forename: Venkatesh
authors.initials: V
authors.lastname: Rangarajan
keywords: HYNIC TOC; MR; SPECT; optic nerve sheath meningioma; somatostatin receptor