title: Novel Imprinted Polymer for the Preconcentration of Cadmium with Determination by Inductively Coupled Plasma Mass Spectrometry.
abstract: A novel Cd(II)-imprinted polymer was prepared with chemical immobilization approach by using N-methacryloyl-L-histidine as a vinylated chelating agent for on-line solid phase extraction of Cd(II) for determination by inductively coupled plasma mass spectrometry. Cd(II)-monomer complex was synthesized and copolymerized via bulk polymerization method in the presence of ethyleneglycoldimethacrylate cross-linker. The resulting polymer was leached with 1.0 mol L-1HNO3to generate the cavities in the polymer for Cd(II) ions. The experimental conditions, including load pH, solution flow rate, and eluent concentration for effective sorption of Cd(II) were optimized using a minicolumn of the imprinted polymer. A volume of 5.0 mL sample 5 μg L-1Cd(II) solution at pH 6.5 was loaded onto the column at 2.0 mL min-1by using a sequential injection system (FIALab 3200) followed by elution with 1.0 mL of 0.75 mol L-1HNO3. The relative selectivity coefficients of the imprinted polymer for Cd(II) were 38.5, 3.5, 3.0, 2.5 and 6.0 in the presence of Cu(II), Ni(II), Zn(II), Co(II) and Pb(II), respectively. Computational calculations revealed that the selectivity of the imprinted polymer was mediated by the stability of Cd(II)-N-methacryloyl-L-histidine complex which was far more stable than those of commonly used monomers, such as 4-vinyl pyridine, methacrylic acid and vinylimidazole. The detection limit (3s) and relative standard deviation (%) were found to be 0.004 μg L-1and 3.2%, respectively. The method was validated by analysis of seawater certified reference material (CASS-4) and successfully applied to the determination of Cd(II) in coastal seawater and estuarine water samples.
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS, USA; Department of Analytical Chemistry, Faculty of Pharmacy, Erciyes University, Kayseri, Turkey.
authors.forename: Vedat
authors.initials: V
authors.lastname: Yilmaz
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS, USA; Deparment of Biomedical Devices and Technologies, Kayseri Vocational School, Erciyes University, Kayseri, Turkey.
authors.forename: Hayriye
authors.initials: H
authors.lastname: Yilmaz
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS, USA.
authors.forename: Zikri
authors.initials: Z
authors.lastname: Arslan
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS, USA.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Leszczynski
keywords: Cadmium; Chemical immobilization; Inductively coupled plasma mass spectrometry; Ion-imprinted polymer; Solid phase extraction