title: Edge-preserving denoising for intra-operative cone beam CT in endovascular aneurysm repair.
abstract: C-arm cone-beam computed tomography (CBCT) acquisition during endovascular aneurysm repair (EVAR) is an emergent technology with more and more applications. It offers real time imaging with a stationary patient and provides 3-D information to achieve guidance of intervention. However, there is growing concern on the overall radiation doses delivered to patients all along the endovascular management due to pre-, intra-, and post-operative X-ray imaging. Manufactures may have their low dose protocols to realize reduction of radiation dose, but CBCT with a low dose protocol has too many artifacts, particularly streak artifacts, and decreased contrast-to-noise ratio (CNR). To reduce noise and artifacts, a penalized weighted least-squares (PWLS) algorithm with an edge-preserving penalty is proposed. The proposed method is evaluated by quantitative parameters including a defined signal-to-noise ratio (SNR), CNR, and modulation transfer function (MTF) on clinical CBCT. Comparisons with PWLS algorithms with isotropic, TV, Huber, anisotropic penalties demonstrate that the proposed edge-preserving penalty performs well not only on edge preservation, but also on streak artifacts suppression, which may be crucial for observing guidewire and stentgraft in EVAR.
authors.affiliation: INSERM, U1099, Rennes, F-35000, France; Université de Rennes 1, LTSI, Rennes, F-35000, France.
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.affiliation: INSERM, U1099, Rennes, F-35000, France; Université de Rennes 1, LTSI, Rennes, F-35000, France.
authors.forename: Miguel
authors.initials: M
authors.lastname: Castro
authors.affiliation: INSERM, U1099, Rennes, F-35000, France; Université de Rennes 1, LTSI, Rennes, F-35000, France; CHU Rennes, Department of Radiology, F-35000, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Lederlin
authors.affiliation: Ctr Rech Informat Med Sino Francais, CRIBs, Rennes, F-35000, France; Southeast University, Laboratory of Image Science and Technology, Key Laboratory of Computer Network and Information Integration of Ministry of Education, Nanjing 210096, Jiangsu, People's Republic of China.
authors.forename: Huazhong
authors.initials: H
authors.lastname: Shu
authors.affiliation: INSERM, U1099, Rennes, F-35000, France; Université de Rennes 1, LTSI, Rennes, F-35000, France; CHU Rennes, Department of Cardiothoracic and Vascular Surgery, F-35000, France.
authors.forename: Adrien
authors.initials: A
authors.lastname: Kaladji
authors.affiliation: INSERM, U1099, Rennes, F-35000, France; Université de Rennes 1, LTSI, Rennes, F-35000, France; Ctr Rech Informat Med Sino Francais, CRIBs, Rennes, F-35000, France. Electronic address: Pascal.Haigron@univ-rennes1.fr.
authors.forename: Pascal
authors.initials: P
authors.lastname: Haigron
mesh_terms: D000465:Algorithms; D000783:Aneurysm / Q000000981:diagnostic imaging* / Q000601:surgery*; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D006801:Humans; D016018:Least-Squares Analysis; D059629:Signal-To-Noise Ratio
keywords: Edge-preserving penalty; Endovascular aneurysm repair; Image denoising; Intra-operative CBCT; Penalized weighted least-squares