title: How many single nucleotide polymorphisms (SNPs) are needed to replace short tandem repeats (STRs) in forensic applications?
abstract: Short tandem repeats (STRs) are the most commonly used forms of genetic information in forensic identification. In recent times, advances in the information on single nucleotide polymorphisms (SNPs) have raised the possibility that these markers could replace the forensically established STRs. In this work, we conducted comparative simulation studies that allowed us to estimate the number of SNPs needed if these markers were used instead of STRs in criminal cases and paternity investigations.
authors.affiliation: Product Development HQ, DonaA-ST, 64, Cheonho-daero, Dondaemun-gu, Seoul, South Korea.
authors.forename: Hyo-Jung
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Statistics, Korea University, 145, Anam-ro, Sungbuk-gu, Seoul, South Korea.
authors.forename: Jae Won
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Department of Statistics, Korea University, 145, Anam-ro, Sungbuk-gu, Seoul, South Korea.
authors.forename: Su Jin
authors.initials: SJ
authors.lastname: Jeong
authors.affiliation: Department of Preventive Medicine, Eulji University, 77, Gyeryong-ro, 771beon-gil, Jung-gu, Daejeon, South Korea. mira@eulji.ac.kr.
authors.forename: Mira
authors.initials: M
authors.lastname: Park
mesh_terms: D016172:DNA Fingerprinting; D030561:Databases, Nucleic Acid; D053803:Forensic Genetics / Q000379:methods; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D018895:Microsatellite Repeats; D010334:Paternity; D020641:Polymorphism, Single Nucleotide; D013223:Statistics as Topic
keywords: Short tandem repeats; Single nucleotide polymorphisms