title: Enteric-Coated, Extended-Release and Sustained-Release Formulations of NSAIDs.
abstract: The scaffold of this commentary is oriented to gravitate toward shedding light on the misconception regarding the use of enteric-coated, extended-release or sustained-release forms of nonsteroidal anti-inflammatory drugs (NSAIDs) and the reduction in gastrointestinal (GI) risks. Although evidence is sufficiently available with regard to the inability of these forms to ameliorate GI risks, it has been widely neglected by health care professionals. This dilemma will be approached and elaborated by uncovering historical evidence about the topic of interest followed by theoretical pharmacological explanations.
authors.affiliation: 1 Higher Colleges of Technology, Dubai, UAE.
authors.forename: Lamia
authors.initials: L
authors.lastname: AlHajri
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000009:adverse effects*; D003692:Delayed-Action Preparations; D041981:Gastrointestinal Tract / Q000187:drug effects*; D006801:Humans; D010437:Peptic Ulcer / Q000139:chemically induced*; D010438:Peptic Ulcer Hemorrhage / Q000139:chemically induced*; D012306:Risk; D013608:Tablets, Enteric-Coated
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D003692:Delayed-Action Preparations; D013608:Tablets, Enteric-Coated
keywords: adult medicine; analgesics; basic; gastroenterology; nonsteroidal anti-inflammatory drugs; pharmacology