title: Percutaneous Vertebroplasty Relieves Pain in Cervical Spine Metastases.
abstract: Percutaneous vertebroplasty (PVP) has been shown to release spinal pain and stabilize the vertebral body. PVP is suggested as an alternative treatment in spinal metastasis. Although cervical metastases is less prevalent than thoracic and lumbar spine, PVP procedure in cervical vertebrae remains technical challenging. We retrospectively analyzed the data from patients (n= 9) who underwent PVP using anterolateral approach to treat severe neck pain and restricted cervical mobility from metastatic disease. Patients were rated using modified Tokuhashi score and Tomita score before the procedure. Visual analog scale (VAS), neck disability index (NDI), analgesic use, and imaging (X-ray or CT) were evaluated before PVP and 3 days, 3 months, and 6 months after PVP. All patients were in late stage of cancer evaluated using modified Tokuhashi and Tomita score. The cement leakage rate was 63.6% (14 of the 22 vertebrae) with no severe complications. VAS, NDI, and analgesic use were significantly decreased 3 days after the procedure and remained at low level until 6 months of follow-up. Our result suggested PVP effectively released the pain from patients with cervical metastasis. The results warrant further clinical investigation.
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Li
authors.initials: L
authors.lastname: Bao
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Pu
authors.initials: P
authors.lastname: Jia
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Jinjun
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Yipeng
authors.initials: Y
authors.lastname: Dong
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Feng
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: He
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Mengmeng
authors.initials: M
authors.lastname: Chen
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Hai
authors.identifier: 0000-0002-9183-0661
authors.initials: H
authors.lastname: Tang
mesh_terms: D000368:Aged; D001843:Bone Cements / Q000627:therapeutic use; D002574:Cervical Vertebrae / Q000601:surgery*; D004185:Disability Evaluation; D017587:Diskectomy, Percutaneous / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019547:Neck Pain / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D010147:Pain Measurement; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000150:complications / Q000556:secondary; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000379:methods*
chemical_list: D001843:Bone Cements