title: [Stimulation of a spermatogenesis in men at a pathospermia and infertility].
abstract: OBJECTIVE
  to investigate of the methods of treatment, directed on increase in quantity of spermatozoa in an ejaculate. MATHERIALS AND METHODS: for this purpose used clomifene and combinations of recombinant FSH with chorionic gonadotrophin (HCG) in 60 men with infertility.
  
  
  RESULTS
  Efficiency of monotherapy by clomiphene was higher and made 20% for conception, and 63% for oligoteratozoospermia. Efficiency of the combined therapy of HCG in combination with recombinant FSH was 40% for conception, and 87% for oligoteratozoospermia. The efficiency of the combined therapy by recombinant FSH and HCG in cases of the previous inefficiency monotherapy HCG and clomifene for oligoteratozoospermia made 65%.
  
  
  CONCLUSIONS
  The combined therapy of HCG in combination with recombinant FSH is al most effective. At the same time the studied types of the stimulating therapy are safe and don't lead to development of side effects.
authors.forename: R V
authors.initials: RV
authors.lastname: Rozhivanov
authors.forename: N S
authors.initials: NS
authors.lastname: Kravtsova
authors.forename: D G
authors.initials: DG
authors.lastname: Kurbatov
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000008:administration & dosage* / Q000009:adverse effects; D002996:Clomiphene / Q000008:administration & dosage* / Q000009:adverse effects; D004359:Drug Therapy, Combination / Q000379:methods; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D013091:Spermatogenesis / Q000187:drug effects*; D000072660:Teratozoospermia / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology
chemical_list: D006063:Chorionic Gonadotropin; D002996:Clomiphene; D005640:Follicle Stimulating Hormone
keywords: clomifene; gonadotrophins; infertility; spermatogenesis