title: Mexametric and cutometric assessment of the signs of aging of the skin area around the eyes after the use of non-ablative fractional laser, non-ablative radiofrequency and intense pulsed light.
abstract: The assessment of the signs of aging within eyes area in cutometric (skin elasticity) and mexametric (discoloration and severity of erythema) examination after the treatment with: non-ablative fractional laser, non-ablative radiofrequency (RF) and intense light source (IPL). This study included 71 patients, aged 33-63 years (the average age was 45.81) with Fitzpatrick skin type II and III. 24 patients received 5 successive treatment sessions with a 1,410-nm non-ablative fractional laser in two-week intervals, 23 patients received 5 successive treatment sessions with a non-ablative RF in one-week intervals and 24 patients received 5 successive treatment sessions with an IPL in two-week intervals. The treatment was performed for the skin in the eye area. The Cutometer and Mexameter (Courage + Khazaka electronic) reference test was used as an objective method for the assessment of skin properties: elasticity, skin pigmentation and erythema. Measurements of skin elasticity were made in three or four sites within eye area. The results of cutometric measurements for R7 showed the improvement in skin elasticity in case of all treatment methods. The largest statistically significant improvement (p < .0001) was observed in case of laser and RF, during treatment sessions, at sites at upper and lower eyelid. The smallest change in skin elasticity for the laser, RF and IPL - p = .017, p = .003 and p = .001, respectively-was observed in a site within the outer corner of the eye. In all sites of measurements and for all methods, the greatest improvement in skin elasticity was demonstrated between the first and second measurement (after 3rd procedures). The majority of the results of mexametric measurements-MEX (melanin level) and ERYT (the severity of erythema) are statistically insignificant. Fractional, non-ablative laser, non-ablation RF and intense light source can be considered as methods significantly affecting elasticity and to a lesser extent erythema and skin pigmentation around the eyes. Fractional non-ablative laser is a method which, in comparison to other methods, has the greatest impact on skin viscoelasticity. These procedures are well tolerated and are associated with a low risk of side effects.
authors.affiliation: Department of Cosmetology and Aesthetic Dermatology, Faculty of Pharmacy, Medical University of Lódź, Muszyńskiego 1 Street, 91 - 151, Łódź, Poland.
authors.forename: Anna Maria
authors.identifier: http://orcid.org/0000-0002-7799-9188
authors.initials: AM
authors.lastname: Kołodziejczak
authors.affiliation: Department of Cosmetology and Aesthetic Dermatology, Faculty of Pharmacy, Medical University of Lódź, Muszyńskiego 1 Street, 91 - 151, Łódź, Poland.
authors.forename: Helena
authors.initials: H
authors.lastname: Rotsztejn
mesh_terms: D000328:Adult; D003357:Cosmetic Techniques / Q000009:adverse effects / Q000295:instrumentation*; D004548:Elasticity; D004867:Equipment Design; D004890:Erythema / Q000209:etiology; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects / Q000295:instrumentation*; D054023:Lasers, Semiconductor / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D061208:Pulsed Radiofrequency Treatment / Q000009:adverse effects; D012060:Rejuvenation; D015595:Skin Aging / Q000528:radiation effects*; D012880:Skin Pigmentation / Q000528:radiation effects; D013997:Time Factors; D016896:Treatment Outcome
keywords: cutometer; intense pulsed light; mexameter; non-ablative fractional laser; non-ablative radiofrequency; skin aging