title: A Test in Context: Myocardial Strain Measured by Speckle-Tracking Echocardiography.
abstract: Strain-based imaging techniques (and specifically speckle-tracking echocardiography) have been shown to have clinical utility in a variety of settings. This technique is being embraced and increasingly adopted in many echocardiography laboratories worldwide. This review appraised speckle-tracking echocardiography in a clinical context by providing a critical evaluation of the prognostic and diagnostic insights that this technology can provide. In particular, we discuss the use of speckle-tracking strain in selected areas, such as undifferentiated left ventricular hypertrophy, cardio-oncology, aortic stenosis, and ischemic heart disease. The potential utility of regional and chamber strains (namely segmental left ventricular strain, left atrial strain, and right ventricular strain) are also discussed. Future directions for this technology are explored. Before its clinical application, it is particularly important that physicians be cognizant of the technical challenges and inherent limitations of strain data, which are also addressed here.
authors.affiliation: Department of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart and Vascular Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and The Cleveland Clinic Foundation, Cleveland, Ohio. Electronic address: colliep@ccf.org.
authors.forename: Patrick
authors.initials: P
authors.lastname: Collier
authors.affiliation: Department of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart and Vascular Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and The Cleveland Clinic Foundation, Cleveland, Ohio.
authors.forename: Dermot
authors.initials: D
authors.lastname: Phelan
authors.affiliation: Department of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart and Vascular Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and The Cleveland Clinic Foundation, Cleveland, Ohio.
authors.forename: Allan
authors.initials: A
authors.lastname: Klein
mesh_terms: D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging*; D015150:Echocardiography, Doppler; D019560:Echocardiography, Three-Dimensional; D006801:Humans
keywords: aortic valve stenosis; cardio-oncology; echocardiography; hypertrophic cardiomyopathy; left ventricular hypertrophy; strain imaging