title: The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM).
abstract: The biological processes that come into play during orthodontic tooth movement (OTM) have been shown to be influenced by a variety of pharmacological agents. The effects of such agents are of particular relevance to the clinician as the rate of tooth movement can be accelerated or reduced as a result. This review aims to provide an overview of recent insights into drug-mediated effects and the potential use of drugs to influence the rate of tooth movement during orthodontic treatment. The limitations of current experimental models and the need for well-designed clinical and pre-clinical studies are also discussed.
authors.affiliation: Department of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, University of Bern Bern, Switzerland.
authors.forename: Thaleia
authors.initials: T
authors.lastname: Kouskoura
authors.affiliation: Department of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, University of Bern Bern, Switzerland.
authors.forename: Christos
authors.initials: C
authors.lastname: Katsaros
authors.affiliation: Institute of Pharmacology, University of Bern Bern, Switzerland.
authors.forename: Stephan
authors.initials: S
authors.lastname: von Gunten
keywords: orthodontic tooth movement; orthodontics; pharmacological agents; pharmacology; tooth movement