title: [Chronic vulvar lymphedema revealing Crohn disease in a teenage girl].
abstract: BACKGROUND
  Cutaneous Crohn disease is a rare cutaneous manifestation of Crohn disease in children. Herein is reported a case of persistent vulvar lymphedema revealing Crohn disease in a teenage girl.
  
  
  METHODS
  A 14-year-old girl presented with an 8-month history of persistent vulvar swelling associated with chronic macrocheilia. Dermatologic examination showed an inflammatory vulvar lymphedema, associated with perianal fissures and hypertrophic gingivitis. Vulvar skin biopsy revealed non-necrotizing granulomatous inflammation. Gastrointestinal endoscopy yielded no significant findings. The diagnosis of Crohn disease presenting as vulvar lymphedema was established. Oral metronidazole therapy resulted in partial improvement of cutaneous lesions beginning the 1st week.
  
  
  CONCLUSIONS
  The originality of this case lies in the presentation of chronic macrocheilia with persistent vulvar lymphedema in a child, revealing Crohn disease without gastrointestinal involvement.
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie. Electronic address: amina_aounallah@yahoo.fr.
authors.forename: A
authors.initials: A
authors.lastname: Aounallah
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: N
authors.initials: N
authors.lastname: Ghariani Fetoui
authors.affiliation: Service d'hépatogastroentérologie, CHU Sahloul, Hammam Sousse, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Ksiaa
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: L
authors.initials: L
authors.lastname: Boussofara
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: W
authors.initials: W
authors.lastname: Saidi
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: S
authors.initials: S
authors.lastname: Mokni
authors.affiliation: Laboratoire d'anatomie et de cytologie pathologique, CHU Farhat Hached, Sousse, Tunisie.
authors.forename: B
authors.initials: B
authors.lastname: Sriha
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: C
authors.initials: C
authors.lastname: Belajouza
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Denguezli
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: N
authors.initials: N
authors.lastname: Ghariani
authors.affiliation: Service de dermatologie, CHU Farhat Hached, avenue Ibn El Jazzar, 4000 Sousse, Tunisie.
authors.forename: R
authors.initials: R
authors.lastname: Nouira
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002908:Chronic Disease; D003424:Crohn Disease / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008209:Lymphedema / Q000175:diagnosis* / Q000473:pathology; D035583:Rare Diseases; D012867:Skin / Q000473:pathology; D014844:Vulva / Q000473:pathology; D014845:Vulvar Diseases / Q000175:diagnosis* / Q000473:pathology