title: 90Y Liver Radioembolization Imaging Using Amplitude-Based Gated PET/CT.
abstract: The usage of PET/CT to monitor patients with hepatocellular carcinoma following Y radioembolization has increased; however, image quality is often poor because of low count efficiency and respiratory motion. Motion can be corrected using gating techniques but at the expense of additional image noise. Amplitude-based gating has been shown to improve quantification in FDG PET, but few have used this technique in Y liver imaging. The patients shown in this work indicate that amplitude-based gating can be used in Y PET/CT liver imaging to provide motion-corrected images with higher estimates of activity concentration that may improve posttherapy dosimetry.
authors.affiliation: From the Department of Radiology, University of Tennessee Graduate School of Medicine, University of Tennessee Medical Center, Knoxville, TN.
authors.forename: Dustin R
authors.initials: DR
authors.lastname: Osborne
authors.forename: Shelley
authors.initials: S
authors.lastname: Acuff
authors.forename: Melissa
authors.initials: M
authors.lastname: Neveu
authors.forename: Austin
authors.initials: A
authors.lastname: Kaman
authors.forename: Mumtaz
authors.initials: M
authors.lastname: Syed
authors.forename: Yitong
authors.initials: Y
authors.lastname: Fu
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D004621:Embolization, Therapeutic; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D015021:Yttrium Radioisotopes / Q000627:therapeutic use*
chemical_list: D019275:Radiopharmaceuticals; D015021:Yttrium Radioisotopes; D019788:Fluorodeoxyglucose F18