title: Diminished protein-bound ω-hydroxylated ceramides in the skin of patients with ichthyosis with 12R-lipoxygenase (LOX) or eLOX-3 deficiency.
authors.affiliation: Department of Pediatrics, University of Erlangen-Nürnberg, D-91054, Erlangen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Dick
authors.affiliation: Department of Dermatology, University of Köln, D-50937, Köln, Germany.
authors.forename: I
authors.initials: I
authors.lastname: Tantcheva-Poór
authors.affiliation: Department of Dermatology, University Hospital of Münster, D-48149, Münster, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Oji
authors.affiliation: Center for Rare and Genetic Skin Diseases, Department of Dermatology, Ludwig-Maximilian University, D-80337, München, Germany.
authors.forename: K A
authors.initials: KA
authors.lastname: Giehl
authors.affiliation: Institute for Human Genetics, University Hospital of Freiburg, D-79106, Freiburg, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Fischer
authors.affiliation: Molecular Diagnostics of Oncogenic Infections, Deutsches Krebsforschungszentrum, D-69120, Heidelberg, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Krieg
authors.affiliation: Department of Pediatrics, University of Erlangen-Nürnberg, D-91054, Erlangen, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Schneider
authors.affiliation: Department of Pediatrics, University of Erlangen-Nürnberg, D-91054, Erlangen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Rauh
mesh_terms: D001092:Arachidonate 12-Lipoxygenase / Q000172:deficiency* / Q000235:genetics; D001094:Arachidonate 5-Lipoxygenase / Q000235:genetics; D016022:Case-Control Studies; D002518:Ceramides / Q000378:metabolism*; D002648:Child; D006720:Homozygote; D006801:Humans; D007057:Ichthyosis / Q000378:metabolism*; D008084:Lipoxygenase / Q000172:deficiency*; D009154:Mutation / Q000235:genetics; D012867:Skin / Q000737:chemistry*
chemical_list: D002518:Ceramides; C511051:ALOXE3 protein, human; D008084:Lipoxygenase; C514086:ALOX12B protein, human; D001092:Arachidonate 12-Lipoxygenase; D001094:Arachidonate 5-Lipoxygenase; C583212:ALOX5 protein, human