title: Rh-Catalyzed Asymmetric Hydrogenation of α-Substituted Vinyl Sulfones: An Efficient Approach to Chiral Sulfones.
abstract: Rh/(S)-(+)-DTBM-Segphos complex catalyzed asymmetric hydrogenation of α-substituted vinyl sulfones has been achieved, furnishing the desired products in high yields and excellent enantioselectivities (>90% yield, up to 99% ee). This method provided an efficient approach to α-substituted chiral sulfones under mild conditions and has potential applications in organic synthesis.
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors.forename: Liyang
authors.initials: L
authors.lastname: Shi
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors.forename: Biao
authors.initials: B
authors.lastname: Wei
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors.forename: Xuguang
authors.initials: X
authors.lastname: Yin
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Xue
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Lv
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.|Department of Chemistry, South University of Science and Technology of China , Shenzhen, Guangdong 518055, P. R. China.
authors.forename: Xumu
authors.identifier: 0000-0001-5700-0608
authors.initials: X
authors.lastname: Zhang