title: Incidence of prostate cancer at a single tertiary care center in North Karnataka.
abstract: BACKGROUND
  Prostate cancer (PC) remains one of the most common cancers affecting men today. Thus, understanding the prevalence, disease characteristics, and changing demographics of Indian PC patients has emerged as an important aspect of study.
  
  
  OBJECTIVE
  We aimed to present the case series of PC patients from single tertiary care center in North Karnataka.
  
  
  METHODS
  The study designed over a period of 8 years from 2007 to 2015 was conducted in the Department of Urology, KLES Dr. Prabhakar Kore Hospital, Belagavi, Karnataka.
  
  
  METHODS
  A total of 471 newly diagnosed patients with PC from 2007 to 2015 were included in the study. Sociodemographic, clinical characteristics, radiological and histopathological findings of all patients were collected and analyzed for the risk of PC.
  
  
  METHODS
  The statistical analysis used in this study was IBM SPSS Statistics software Inc., version 20.0.
  
  
  RESULTS
  A total of 471 patients were diagnosed with PC, the mean age at presentation was 70 years, and mean prostate-specific antigen (PSA) level was 37.71 ng/mL. Digital rectal examination (DRE) was abnormal in 87.5% of 471 cases. Significant correlation was observed between PSA level and DRE (P = 0.0005), correlation of PSA and Gleason's score was P = 0.0006, and histopathological results showed high risk in patients (P = 0.0001).
  
  
  CONCLUSIONS
  This is the first hospital-based study of PC incidence with clinical and histopathological features. PC remains an important public health problem with increasing incidence and significant burden on health-care resources in India.
authors.affiliation: Department of Biotechnology and Microbiology, Karnatak University, Dharwad, Karnataka, India.
authors.forename: S C
authors.initials: SC
authors.lastname: Ghagane
authors.affiliation: Department of Urology, KLES Kidney Foundation, KLES Dr. Prabhakar Kore Hospital, Belagavi, Karnataka, India.
authors.forename: R B
authors.initials: RB
authors.lastname: Nerli
authors.affiliation: Department of Biotechnology and Microbiology, Karnatak University, Dharwad, Karnataka, India.
authors.forename: M B
authors.initials: MB
authors.lastname: Hiremath
authors.affiliation: Department of Urology, KLES Kidney Foundation, KLES Dr. Prabhakar Kore Hospital, Belagavi, Karnataka, India.
authors.forename: A T
authors.initials: AT
authors.lastname: Wagh
authors.affiliation: Department of Urology, KLES Kidney Foundation, KLES Dr. Prabhakar Kore Hospital, Belagavi, Karnataka, India.
authors.forename: P V
authors.initials: PV
authors.lastname: Magdum
mesh_terms: D000368:Aged; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D008297:Male; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology; D062606:Tertiary Care Centers