title: Synthesis of sandwich-like molybdenum sulfide/mesoporous organosilica nanosheets for photo-thermal conversion and stimuli-responsive drug release.
abstract: Sandwich-like molybdenum sulfide/mesoporous organosilica nanosheets (denoted as MoS2@MOS) have been prepared for the first time via direct growth of ethane-bridged mesostructured organosilica on MoS2nanosheets by using cetyltrimethylammonium bromide (CTAB) as structure directing agent. The obtained MoS2@MOS nanosheets possess well-defined sandwich-like structure, high surface area (∼920cm2/g), uniform pore size (∼4.2nm), large pore volume (∼1.41cm3g-1). In vitro cytotoxicity assessments demonstrate that the MoS2@MOS nanosheets have excellent biocompatibility. Owing to the encapsulation of the MoS2, the obtained MoS2@MOS nanosheets have photo-thermal conversion capability and photo-thermally controlled drug release property. These properties make the MoS2@MOS nanosheets promising for biomedical applications.
authors.affiliation: Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210046, PR China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Su
authors.affiliation: Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210046, PR China.
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
authors.affiliation: Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210046, PR China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210046, PR China.
authors.forename: Lihui
authors.initials: L
authors.lastname: Yuwen
authors.affiliation: Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210046, PR China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210046, PR China.
authors.forename: Meng
authors.initials: M
authors.lastname: Dang
authors.affiliation: Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210046, PR China.
authors.forename: Jun
authors.initials: J
authors.lastname: Tao
authors.affiliation: School of Optoelectronic Engineering, Nanjing University of Posts and Telecommunications (NUPT), Nanjing 210023, PR China. Electronic address: maxiaobo@njupt.edu.cn.
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Ma
authors.affiliation: Department of Medical Imaging, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, PR China. Electronic address: Shouju.wang@gmail.com.
authors.forename: Shouju
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Medical Imaging, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, PR China. Electronic address: zhaogangteng@163.com.
authors.forename: Zhaogang
authors.initials: Z
authors.lastname: Teng
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D001672:Biocompatible Materials / Q000737:chemistry; D002470:Cell Survival / Q000187:drug effects; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D004220:Disulfides / Q000737:chemistry* / Q000633:toxicity; D004317:Doxorubicin / Q000737:chemistry / Q000494:pharmacology; D016503:Drug Delivery Systems; D065546:Drug Liberation; D006358:Hot Temperature; D006801:Humans; D007834:Lasers; D061986:MCF-7 Cells; D008982:Molybdenum / Q000737:chemistry* / Q000633:toxicity; D049329:Nanostructures / Q000737:chemistry* / Q000528:radiation effects / Q000633:toxicity; D017646:Organosilicon Compounds / Q000737:chemistry* / Q000633:toxicity; D010316:Particle Size; D016062:Porosity; D013499:Surface Properties
chemical_list: D000970:Antineoplastic Agents; D001672:Biocompatible Materials; D002593:Cetrimonium Compounds; D004220:Disulfides; D017646:Organosilicon Compounds; D004317:Doxorubicin; D008982:Molybdenum; D000077286:Cetrimonium; C082964:molybdenum disulfide
keywords: Drug release; Mesoporous organosilica; MoS(2); Photo-thermal conversion; Sandwich structure