title: Antibiotic therapy in the critically ill - expert opinion of the Intensive Care Medicine Scientific Subcommittee of the European Society of Anaesthesiology.
abstract: Antimicrobial treatment is the cornerstone of infection treatment, and the selection of appropriate antibiotic treatment for critically ill patients is challenging. Clinicians working with critically ill patients usually feel a greater obligation towards their patient than towards maintenance of the delicate ecological balance of prevalent microbiological threats and their resistance patterns. Although antibiotic overtreatment is a frequent phenomenon, patient outcomes need not be compromised when antibiotic treatment is driven by informed decision-making.At the 2016 Euro Anaesthesia Conference (London, UK), the European Society of Anaesthesia Intensive Care Scientific Subcommittee convened an expert panel on antibiotic therapy. This article summarises the main conclusions of the panel, namely the principles of antibiotic therapy that all physicians working with critically ill patients must know.
authors.affiliation: From the Multidisciplinary Intensive Care, St James's University Hospital (IML); Department of Clinical Medicine, Trinity College, Dublin, Ireland (IML); Anaesthesia and Intensive Care Unit and Trauma Centre, Aix Marseille University, Nord Hospital, Assistance Publique Hôpitaux de Marseille, APHM, Marseille, France (ML, CM); Department of Anaesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary (KM); General Intensive Care Unit, Shaare Zedek Medical Centre, Hebrew University Faculty of Medicine, Jerusalem, Israel (SE).
authors.forename: Ignacio
authors.initials: I
authors.lastname: Martin-Loeches
authors.forename: Marc
authors.initials: M
authors.lastname: Leone
authors.forename: Krisztina
authors.initials: K
authors.lastname: Madách
authors.forename: Claude
authors.initials: C
authors.lastname: Martin
authors.forename: Sharon
authors.initials: S
authors.lastname: Einav
mesh_terms: D000776:Anesthesiology / Q000379:methods / Q000592:standards*; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000073602:Antimicrobial Stewardship / Q000379:methods / Q000592:standards; D003422:Critical Care / Q000379:methods / Q000592:standards*; D016638:Critical Illness / Q000453:epidemiology / Q000628:therapy*; D004352:Drug Resistance, Microbial / Q000187:drug effects / Q000502:physiology; D005060:Europe / Q000453:epidemiology; D006801:Humans; D007362:Intensive Care Units / Q000592:standards; D012955:Societies, Medical / Q000592:standards*
chemical_list: D000900:Anti-Bacterial Agents