title: Prediction of infarct size using two-dimensional speckle tracking echocardiography in acute myocardial infarction.
abstract: BACKGROUND
  This study aimed to determine the myocardial damage (infarct size provided by cardiac single-photon emission tomography) in early stages of the infarction using longitudinal strain and rotational parameters of the left ventricle.
  
  
  METHODS
  The study included 66 patients with anterior myocardial infarction (AMI) and 62 patients with inferior myocardial infarction (IMI) who underwent primary percutaneous intervention as well as a control group consisting of 50 healthy subjects. LV rotational parameters based on parasternal short-axis views in basal and apical planes and global longitudinal strain were measured with apical four-chamber, apical two-chamber, and apical long-axis views.
  
  
  RESULTS
  There was a significant positive correlation between infarct size and GLPSavg (r=-.55 <.001), GTOR angle (r=-.52, P<.001), apical rotation angle (r=-.40 <.001, and EF (r=-.43, <.001). While cutoff values were GLPSavg: 11.9 (AUC=0.78), GTOR angle: 11.4° (AUC=0.77), apical rotation angle: 7.1° (AUC=0.76) for patients with an infarct size greater than 20%, the cutoff values were GLPSavg: 10.7 (AUC=0.75), GTOR angle: 8.7° (AUC=0.86), apical rotation angle: 4.35° (AUC=0.87) for those with an infarct size greater than 40%.
  
  
  CONCLUSIONS
  GLPSavg, GTOR angle, and apical rotation angle values may be used to determine the extent of infarction in early post-MI period, thereby allowing precautions to be taken for remodeling in early stages.
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Cem
authors.identifier: http://orcid.org/0000-0002-2004-142X
authors.initials: C
authors.lastname: Doğan
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Zübeyde
authors.initials: Z
authors.lastname: Bayram
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Özkan
authors.initials: Ö
authors.lastname: Candan
authors.affiliation: Faculty of Medicine, Cardiology Department, Medipol University, İstanbul, Turkey.
authors.forename: Onur
authors.initials: O
authors.lastname: Omaygenç
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Yılmaz
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Rezzan Deniz
authors.initials: RD
authors.lastname: Acar
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Özgür Yaşar
authors.initials: ÖY
authors.lastname: Akbal
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Cihangir
authors.initials: C
authors.lastname: Kaymaz
authors.affiliation: Cardiology Department, Kartal Kosuyolu Education and Research Hospital, İstanbul, Turkey.
authors.forename: Nihal
authors.initials: N
authors.lastname: Özdemir
mesh_terms: D000208:Acute Disease; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D012720:Severity of Illness Index; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology*
keywords: myocardial infarction; myocardial perfusion; radionuclide imaging; strain