title: Abnormal Auditory Brainstem Response (ABR) Findings in a Near-Normal Hearing Child with Noonan Syndrome.
abstract: BACKGROUND
  Noonan syndrome (NS) is a heterogeneous genetic disease that affects many parts of the body. It was named after Dr. Jacqueline Anne Noonan, a paediatric cardiologist.
  
  
  METHODS
  We report audiological tests and auditory brainstem response (ABR) findings in a 5-year old Malay boy with NS. Despite showing the marked signs of NS, the child could only produce a few meaningful words. Audiological tests found him to have bilateral mild conductive hearing loss at low frequencies. In ABR testing, despite having good waveform morphology, the results were atypical. Absolute latency of wave V was normal but interpeak latencies of wave's I-V, I-II, II-III were prolonged. Interestingly, interpeak latency of waves III-V was abnormally shorter.
  
  
  CONCLUSIONS
  Abnormal ABR results are possibly due to abnormal anatomical condition of brainstem and might contribute to speech delay.
authors.affiliation: Department of Audiology, Faculty of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Bahram
authors.initials: B
authors.lastname: Jalaei
authors.affiliation: Audiology Program, School of Health Sciences, University Sains Malaysia, Kelantan, Malaysia.
authors.forename: Mohd Normani
authors.initials: MN
authors.lastname: Zakaria
authors.affiliation: Department of Otorhinolaryngology, School of Medical Sciences, University Sains Malaysia, Kelantan, Malaysia.
authors.forename: Dinsuhaimi
authors.initials: D
authors.lastname: Sidek
keywords: Audiological evaluation; Auditory Brainstem response (ABR); Hearing loss; Noonan Syndrome