title: Legionellosis acquired through a dental unit: a case study.
abstract: In 2012, an elderly immunocompromised man died from legionellosis at a hospital in Uppsala, Sweden. The patient had visited a dental ward at the hospital during the incubation period. Legionella spp. at a concentration of 2000 colony-forming units/L were isolated from the cupfiller outlet providing water for oral rinsing. Isolates from the patient and the dental unit were Legionella pneumophila serogroup 1, subgroup Knoxville and ST9. Pulsed-field gel electrophoresis and whole-genome sequencing strongly suggested that the isolates were of common origin. This report presents one of few documented cases of legionellosis acquired through a dental unit.
authors.affiliation: Department of Surveillance and Coordination, Public Health Agency of Sweden, Sweden. Electronic address: caroline.schonning@folkhalsomyndigheten.se.
authors.forename: C
authors.initials: C
authors.lastname: Schönning
authors.affiliation: Department of Microbiology, Public Health Agency of Sweden, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Jernberg
authors.affiliation: Department of Microbiology, Public Health Agency of Sweden, Sweden.
authors.forename: D
authors.initials: D
authors.lastname: Klingenberg
authors.affiliation: Department of Microbiology, Public Health Agency of Sweden, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Andersson
authors.affiliation: Department of Microbiology, Public Health Agency of Sweden, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Pääjärvi
authors.affiliation: Department of Microbiology, Public Health Agency of Sweden, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Alm
authors.affiliation: Section of Infectious Diseases, Department of Medical Sciences, Uppsala University, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Tano
authors.affiliation: Section of Clinical Microbiology, Department of Medical Sciences, Uppsala University, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Lytsy
mesh_terms: D000368:Aged; D015169:Colony Count, Microbial / Q000379:methods; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality; D003770:Dental Offices / Q000592:standards*; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods; D017809:Fatal Outcome; D006760:Hospitalization; D006801:Humans; D016867:Immunocompromised Host; D016952:Legionella pneumophila / Q000145:classification / Q000235:genetics / Q000254:growth & development* / Q000302:isolation & purification; D007876:Legionellosis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality; D007877:Legionnaires' Disease / Q000175:diagnosis* / Q000382:microbiology / Q000652:urine; D008297:Male; D012703:Serotyping / Q000379:methods; D013548:Sweden / Q000453:epidemiology; D014871:Water Microbiology; D000073336:Whole Genome Sequencing / Q000379:methods
keywords: Dental unit; Epidemiological typing; Legionella; SBT; WGS