title: Pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome: differential diagnosis of septic arthritis by regular detection of exceedingly high synovial cell counts.
abstract: Pyogenic arthritis, pyoderma gangrenosum and acne syndrome was diagnosed in a 42-year-old patient, after an unusual persistency of high synovial cell counts had been noticed. Clinical peculiarities and problems with diagnosing septic versus non-septic arthritis are discussed.
authors.affiliation: Rheumatologie Nymphenburg, Nymphenburger Str. 108a, 80636, Munich, Germany. werner.e.loeffler@web.de.
authors.forename: W
authors.initials: W
authors.lastname: Löffler
authors.affiliation: Institut für Laboratoriumsmedizin, Virchowstr. 10 c, 78224, Singen, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Lohse
authors.affiliation: Allgemeinmedizin und Sportmedizin Nymphenburg, Nymphenburger Str. 108a, 80636, Munich, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Weihmayr
authors.affiliation: Allgemeinmedizin und Sportmedizin Nymphenburg, Nymphenburger Str. 108a, 80636, Munich, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Widenmayer
mesh_terms: D000152:Acne Vulgaris / Q000175:diagnosis*; D001170:Arthritis, Infectious / Q000175:diagnosis*; D002452:Cell Count; D003937:Diagnosis, Differential; D006801:Humans; D017511:Pyoderma Gangrenosum / Q000175:diagnosis*; D013583:Synovial Membrane / Q000166:cytology*
keywords: Acne; Anakinra; Arthritis; Autoinflammatory; Canakinumab; Corticosteroids; Exercise induced; Il-1 blocking; PAPA syndrome; PSTPIP1; Pyoderma gangrenosum; Pyogenic; Septic; Synovial fluid cell counts; TNF alpha blocking