title: Epigenomic Changes Prime PDAC Metastasis.
abstract: Widespread chromatin modifications and DNA methylation could be responsible for inducing the spread of pancreatic ductal adenocarcinoma cells to distant sites, according to recent research. The findings also implicate glucose metabolism as a driver of metastasis.
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D021441:Carcinoma, Pancreatic Ductal / Q000235:genetics* / Q000473:pathology; D045744:Cell Line, Tumor; D002843:Chromatin / Q000235:genetics*; D019175:DNA Methylation / Q000235:genetics*; D057890:Epigenomics; D006801:Humans; D009362:Neoplasm Metastasis; D011401:Promoter Regions, Genetic
chemical_list: D002843:Chromatin