title: Alzheimer's disease as an inflammatory disease.
abstract: Alzheimer's disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia. In this short review, we focus on neuroinflammation in AD. Specifically, we describe the participation of microglia, as well as other factors that may contribute to inflammation, in neurodegeneration.
authors.affiliation: Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Valderrebollo 5, E-28041-Madrid, Spain.|Centro de Biología Molecular "Severo Ochoa" CSIC-UAM, Nicolás Cabrera 1, E-28049-Madrid, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Bolós
authors.affiliation: Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Valderrebollo 5, E-28041-Madrid, Spain.|Centro de Biología Molecular "Severo Ochoa" CSIC-UAM, Nicolás Cabrera 1, E-28049-Madrid, Spain.
authors.forename: Juan Ramón
authors.identifier: https://orcid.org/0000-0001-7607-8814
authors.initials: JR
authors.lastname: Perea
authors.affiliation: Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Valderrebollo 5, E-28041-Madrid, Spain.|Centro de Biología Molecular "Severo Ochoa" CSIC-UAM, Nicolás Cabrera 1, E-28049-Madrid, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Avila
mesh_terms: D000544:Alzheimer Disease / Q000276:immunology* / Q000378:metabolism* / Q000473:pathology; D000818:Animals; D006801:Humans; D007249:Inflammation / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D017628:Microglia / Q000378:metabolism; D019636:Neurodegenerative Diseases / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D016875:tau Proteins / Q000378:metabolism
chemical_list: D016875:tau Proteins