title: An efficient Sn(ii)-catalyzed one-pot synthesis of a 3-substituted azetidine-2,4-dione framework.
abstract: A novel Sn(ii)-catalyzed tandem cyclization reaction of aromatic aldehydes with ethyl cyanoacetate has been achieved to afford a series of 3-substituted azetidine-2,4-diones in good to excellent yields. This protocol provides straightforward access to construct the azetidine core through sequential Knoevenagel condensation, hydration and the C-N cyclization reaction.
authors.affiliation: Chemical Engineering and Process Development Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune, Maharashtra 411008, India. gm.suryavanshi@ncl.res.in.
authors.forename: Santosh S
authors.initials: SS
authors.lastname: Chavan
authors.forename: Mrudul V
authors.initials: MV
authors.lastname: Supekar
authors.forename: Pralhad A
authors.initials: PA
authors.lastname: Burate
authors.forename: Bapurao D
authors.initials: BD
authors.lastname: Rupanwar
authors.forename: Anil M
authors.initials: AM
authors.lastname: Shelke
authors.forename: Gurunath
authors.initials: G
authors.lastname: Suryavanshi