title: Tuberculosis After Renal Transplant.
abstract: Tuberculosis is one of the leading infections after renal transplant, particularly in developing countries where the incidence and prevalence in the general population are high. Diagnosis requires bacteriologic and histologic confirmation. Interactions among the antitubercular drugs and the immunosuppressive agents have to be considered while prescribing, and surveillance for adverse effects is required. Although rare, case reports are available on extrapulmonary tuberculosis in allograft recipients. Here, we present a 25-year-old kidney transplant recipient who was diagnosed with lymph node tuberculosis under uncommon circumstances but who had a good outcome. This case report illustrates the difficulties in diagnosis of tuberculosis, changes in therapeutic protocols, and prognostic factors and highlights the effects of infectious complications with immunosuppressive therapy in this particular patient population.
authors.affiliation: Nephrology Department, Laboratory of Renal Pathology and Laboratory of Kidney Transplantation Immunology and Immunopathology, Charles Nicolle Hospital, Tunis, Tunisia.
authors.forename: Samia
authors.initials: S
authors.lastname: Barbouch
authors.forename: Meriam
authors.initials: M
authors.lastname: Hajji
authors.forename: Imed
authors.initials: I
authors.lastname: Helal
authors.forename: Mondher
authors.initials: M
authors.lastname: Ounissi
authors.forename: Mohammed Mongi
authors.initials: MM
authors.lastname: Bacha
authors.forename: Fathi
authors.initials: F
authors.lastname: Ben Hamida
authors.forename: Ezzedine
authors.initials: E
authors.lastname: Abderrahim
authors.forename: Taieb
authors.initials: T
authors.lastname: Ben Abdallah
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004322:Drainage; D004359:Drug Therapy, Combination; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000302:isolation & purification*; D009894:Opportunistic Infections / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology* / Q000628:therapy; D014463:Ultrasonography
chemical_list: D000995:Antitubercular Agents; D007166:Immunosuppressive Agents