title: Gene of the issue: RUNX1 mutations and inherited bleeding.
authors.affiliation: a Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham , Birmingham , UK.
authors.forename: Neil V
authors.initials: NV
authors.lastname: Morgan
authors.affiliation: b Department of Infection , Immunity and Cardiovascular Disease, University of Sheffield , Sheffield , UK.
authors.forename: Martina E
authors.initials: ME
authors.lastname: Daly
mesh_terms: D025861:Blood Coagulation Disorders, Inherited / Q000235:genetics* / Q000473:pathology; D001791:Blood Platelet Disorders / Q000235:genetics* / Q000473:pathology; D001792:Blood Platelets / Q000378:metabolism* / Q000473:pathology; D002891:Chromosomes, Human, Pair 21 / Q000737:chemistry; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics*; D015870:Gene Expression; D005799:Genes, Dominant; D006470:Hemorrhage / Q000151:congenital / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology; D009154:Mutation; D010976:Platelet Count; D000072417:Protein Domains; D012333:RNA, Messenger / Q000235:genetics*
chemical_list: D050676:Core Binding Factor Alpha 2 Subunit; D012333:RNA, Messenger; C493728:RUNX1 protein, human
keywords: Bleeding; RUNX1 gene; inherited mutations; platelets