title: Long-standing indeterminate biliary stricture with iterative negative tissue sampling revealed as cholangiocarcinoma under SpyGlassTM cholangiocoscopy.
abstract: Bile duct brush cytology, intraductal biopsy and EUS-FNA are all used to characterize biliary strictures, with suboptimal sensitivity. Surgical resection without confirmed malignancy is undesirable. Cholangioscopy with targeted biopsies appears to increase the diagnostic yield in indeterminate biliary strictures, but it is still considered optional.
authors.affiliation: Aparato Digestivo, Hospital Universitario de Gran Canaria Dr. Negrín, España.
authors.forename: Andrés
authors.initials: A
authors.lastname: Figueroa Marrero
authors.affiliation: Aparato Digestivo, Hospital de La Princesa, España.
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Chavarría-Herbozo
authors.affiliation: Hospital Universitario Río Hortega, Valladolid.
authors.forename: Carlos
authors.initials: C
authors.lastname: de la Serna Higuera
authors.affiliation: Hospital Universitario Rio Hortega, Valladolid.
authors.forename: Manuel
authors.initials: M
authors.lastname: Pérez-Miranda
mesh_terms: D001650:Bile Duct Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D002779:Cholestasis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D006801:Humans; D008297:Male; D008875:Middle Aged