title: Life-Saving Degeneracy in the Human Immune System.
abstract: Different human immune system components coordinate to ensure effective control of pathogens. Israel et al. (2017) examine the immune system of a patient with an inborn genetic error, presenting as impaired TLR signaling and staphylococcal disease, and uncover a beautiful example of degeneracy between innate and adaptive branches of immunity.
authors.affiliation: Science for Life laboratory, Department of Medicine, Solna, Karolinska Institutet, 17177 Stockholm, Sweden; Department of Neonatology, Karolinska University Hospital, 17176 Stockholm, Sweden. Electronic address: petter.brodin@ki.se.
authors.forename: Petter
authors.initials: P
authors.lastname: Brodin
mesh_terms: D006801:Humans; D007107:Immune System; D007113:Immunity, Innate / Q000276:immunology*; D015398:Signal Transduction
keywords: human immunology; immunodeficiency; immunology; newborn immune system; pediatrics; systems immunology