title: Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration.
abstract: This study aimed to evaluate the ability of quantitative light-induced fluorescence (QLF) to assess caries lesion activity using visual examination (VE) as the gold standard. Twenty-four visible white spot lesions on buccal surfaces were examined from 23 children, ages 9 to 14 years. At baseline, the surface was hydrated with water, and thereafter, it was dehydrated with continuous compressed air during image acquisition. QLF images were acquired at 0 (baseline), 5, and 15 s. QLF variables [ QLF V : fluorescence loss ( ? F ), lesion size (S), ? Q : ? F × S ] was recorded. Changes-in- QLF V per second ( ? QLF V ) were determined: ? QLF V = ( QLF VN ? QLF V Baseline ) / N , where N indicates dehydration time. One experienced dentist conducted VE independently using a dental unit’s light, compressed air, and explorer.
authors.affiliation: Indiana University School of Dentistry, Department of Cariology, Operative Dentistry and Dental Public Health, Indianapolis, Indiana, United States.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Ando
authors.affiliation: University of North Carolina at Chapel Hill, School of Dentistry Department of Operative Dentistry, Chapel Hill, North Carolina, United States.
authors.forename: Andrea G
authors.initials: AG
authors.lastname: Ferreira-Zandoná
authors.affiliation: Indiana University School of Medicine, Department of Biostatistics, Indianapolis, Indiana, United States.
authors.forename: George J
authors.initials: GJ
authors.lastname: Eckert
authors.affiliation: Indiana University School of Dentistry, Department of Cariology, Operative Dentistry and Dental Public Health, Indianapolis, Indiana, United States.
authors.forename: Domenick T
authors.initials: DT
authors.lastname: Zero
authors.affiliation: Therametric Technologies, Inc., Noblesville, Indiana, United States.
authors.forename: George K
authors.initials: GK
authors.lastname: Stookey
mesh_terms: D000293:Adolescent; D002648:Child; D003731:Dental Caries / Q000000981:diagnostic imaging*; D003890:Desiccation; D005453:Fluorescence; D006801:Humans; D008027:Light; D010865:Pilot Projects; D013050:Spectrometry, Fluorescence