title: Squaramide-Catalyzed Asymmetric Reactions.
abstract: Bifunctional squaramides have emerged as powerful hydrogen-bonding catalysts for promoting a wide array of useful asymmetric reactions, which provides convenient methods for the construction of complex molecular structures and chiral biologically active compounds. This review highlights the recent advances of our research group in the chiral squaramide-catalyzed asymmetric reactions, including Michael addition, Mannich reaction, aza-Henry reaction, Strecker reaction as well as cascade or sequential reactions.
authors.affiliation: School of Chemistry and Chemical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Beijing, 100081, People's Republic of China.
authors.forename: Bo-Liang
authors.initials: BL
authors.lastname: Zhao
authors.affiliation: School of Chemistry and Chemical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Beijing, 100081, People's Republic of China.
authors.forename: Jun-Hua
authors.initials: JH
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Beijing, 100081, People's Republic of China.
authors.forename: Da-Ming
authors.initials: DM
authors.lastname: Du
keywords: Mannich reaction; Michael addition; asymmetric synthesis; cascade reaction; hydrogen bond; organocatalysis squaramides