title: Brown tumor: clinical findings of secondary hyperparathyroidism in patients with renal osteodystrophy.
abstract: A brown tumor, or osteoclastoma, is a nonneoplastic bony lesion associated with hyperparathyroidism and directly related to increased levels of parathyroid hormone. These tumors result from excessive osteoclastic activity. This article presents 3 cases of brown tumor localized in facial bones. The lesions were the result of secondary hyperparathyroidism associated with chronic renal failure. The patients were two 42-year-old men and a 39-year-old woman. All patients had been treated systemically by hemodialysis for more than 10 years. This article highlights the importance of proper diagnosis and management of dental patients presenting with a brown tumor.
authors.forename: Mairaira Teles Leão E
authors.initials: MT
authors.lastname: Silva
authors.forename: Juliana Silva Barros
authors.initials: JS
authors.lastname: Cedraz
authors.forename: Caetano Guilherme Carvalho
authors.initials: CG
authors.lastname: Pontes
authors.forename: Cleverson Luciano
authors.initials: CL
authors.lastname: Trento
authors.forename: Bernardo Ferreira
authors.initials: BF
authors.lastname: Brasileiro
authors.forename: Marta Rabello
authors.initials: MR
authors.lastname: Piva
authors.forename: Fabiano Alvim
authors.initials: FA
authors.lastname: Pereira
mesh_terms: D000328:Adult; D001847:Bone Diseases / Q000209:etiology* / Q000473:pathology; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications / Q000473:pathology*; D007571:Jaw Diseases / Q000209:etiology / Q000473:pathology*; D008297:Male; D008336:Mandibular Diseases / Q000209:etiology / Q000473:pathology; D008439:Maxillary Diseases / Q000209:etiology / Q000473:pathology
keywords:  brown tumor ;  giant cells ;  parathyroid hormone ;  renal osteodystrophy ;  secondary hyperparathyroidism 