title: First complete genome sequence of a virulent bacteriophage infecting the opportunistic pathogen Serratia rubidaea.
abstract: A Serratia rubidaea phage, vB_Sru IME250, was isolated from hospital sewage. The morphology suggested that phage vB_Sru IME250 should be classified as a member of the family Myoviridae. High-throughput sequencing revealed that the phage genome has 154,938 nucleotides and consists of 193 coding DNA sequences, 90 of which have putative functions. The genome of vB_Sru IME250 is a linear, double-stranded DNA with an average GC content of 40.04%. The phage has a relatively high similarity to Klebsiella phage 0507-KN2-1, with a genome coverage of 84%.
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.
authors.forename: Shaozhen
authors.initials: S
authors.lastname: Xing
authors.affiliation: Department of Immunology, Basic Medical College, Hebei Medical University, Shijiazhuang, 050017, People's Republic of China.|Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, 050017, People's Republic of China.
authors.forename: Taping
authors.initials: T
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.
authors.forename: Xianglilan
authors.initials: X
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Mi
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: An
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China.
authors.forename: Hang
authors.initials: H
authors.lastname: Fan
authors.affiliation: Department of Pathogenic Biology and Immunology, School of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, 050000, China. hbwushui@126.com.
authors.forename: Shuhui
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Immunology, Basic Medical College, Hebei Medical University, Shijiazhuang, 050017, People's Republic of China. weilin501@163.com.|Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang, 050017, People's Republic of China. weilin501@163.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Wei
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, People's Republic of China. tong.yigang@gmail.com.
authors.forename: Yigang
authors.identifier: http://orcid.org/0000-0002-8503-8045
authors.initials: Y
authors.lastname: Tong
mesh_terms: D016679:Genome, Viral; D017900:Myoviridae / Q000235:genetics* / Q000472:pathogenicity*; D010802:Phylogeny; D012705:Serratia / Q000821:virology*; D014774:Virulence