title: Amplitude based beat detection for atrial fibrillation in pacemaker.
abstract: Bradycardia is defined as a sinus rhythm of less than 60 beats per minute and atrial tachyarrhythmia including atrial fibrillation (AF) is frequently associated with bradycardia. Pacemaker is the only effective treatment for symptomatic bradycardia and automatic mode switching (AMS) function is built in pacemaker to switch mode in the presence of atrial tachyarrhythmia. AMS algorithms consider appropriate mode switching in case of undersensing or oversensing and this consideration makes their onset time and resynchronization time late. Current pacemakers have onset time from 2.5 seconds to 26 seconds and resynchronization time from 3.4 seconds to 143 seconds according to manufacturers. In this work, we proposed beat detection algorithm based on amplitude difference between peak and trough for accurate extraction of atrial rate achieving faster mode switching. Evaluation of beat detection algorithm was conducted with six canine AF electrogram (EGM) data. Result showed 96.64% sensitivity, 95.5% positive predictive value in average. With this, transition from AF to normal sinus rhythm could be detected faster than existing AMS algorithms. In conclusion, proposed algorithm can efficiently detect beats in EGM during AF and from this, we can implement faster AMS algorithm.
authors.lastname: Seung Hwan Lee
authors.lastname: Hyoun Seok Myoung
authors.lastname: Chang Hoon Kang
authors.lastname: Eue Keun Choi
authors.lastname: Kyoung Joung Lee
mesh_terms: D000465:Algorithms; D000818:Animals; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000503:physiopathology / Q000662:veterinary*; D001919:Bradycardia / Q000175:diagnosis / Q000503:physiopathology / Q000662:veterinary; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004283:Dog Diseases / Q000175:diagnosis / Q000503:physiopathology*; D004285:Dogs; D006325:Heart Atria / Q000503:physiopathology; D013610:Tachycardia / Q000175:diagnosis / Q000503:physiopathology / Q000662:veterinary