title: Primary Sjögren's syndrome and bronchiolitis. An unusual association.
abstract: Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly affects the exocrine glands. It has been reported that the association between SS and respiratory involvement occurs in 11% and 45% of cases, and can be the initial manifestation of the disease. The diagnosis is based on the integration of clinical, immunological and histopathological criteria. This paper examines a 58-year-old man with SS, severe dyspnea and recurrent exacerbations associated with bronchiolitis-bronchiectasis. The absence of anti-Ro and anti-La antibodies associated with severe bronchiolitis is a clinical presentation that is poorly characterized in this group of patients; moreover, how to treat them remains unclear.
authors.affiliation: Departamento de Neumología, Hospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, Yucatán, México.
authors.forename: Lourdes
authors.initials: L
authors.lastname: Medina-Paz
authors.affiliation: Departamento de Neumología, Hospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, Yucatán, México.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Che-Morales
authors.affiliation: ANAPAT Laboratorio de Anatomía Patológica, Mérida, Yucatán, México.
authors.forename: Hirian
authors.initials: H
authors.lastname: Alonso Moshe Barrera-Pérez
authors.affiliation: Departamento de Neumología, Hospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, Yucatán, México. Electronic address: dr_morenheim@hotmail.com.
authors.forename: Arturo
authors.initials: A
authors.lastname: Cortes-Telles
mesh_terms: D001988:Bronchiolitis / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis*
keywords: Bronchiolitis; Bronquiolitis; Primary Sjögren syndrome; Síndrome de Sjögren primario; Tratamiento; Treatment