title: General and Efficient C-C Bond Forming Photoredox Catalysis with Semiconductor Quantum Dots.
abstract: Photoredox catalysis has become an essential tool in organic synthesis because it enables new routes to important molecules. However, the best available molecular catalysts suffer from high catalyst loadings and rely on precious metals. Here we show that colloidal nanocrystal quantum dots (QDs) can serve as efficient and robust, precious-metal free, photoassisted redox catalysts. A single-sized CdSe quantum dot (3.0 ± 0.2 nm) can replace several different dye catalysts needed for five different photoredox reactions (β-alkylation, β-aminoalkylation, dehalogenation, amine arylation, and decarboxylative radical formation). Even without optimization of the QDs or the reaction conditions, efficiencies rivaling those of the best available metal dyes were obtained.
authors.affiliation: Department of Chemistry, University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Jill A
authors.initials: JA
authors.lastname: Caputo
authors.affiliation: Department of Chemistry, University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Leah C
authors.identifier: 0000-0002-0703-783X
authors.initials: LC
authors.lastname: Frenette
authors.affiliation: Department of Chemistry, University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Norman
authors.identifier: 0000-0001-7097-0617
authors.initials: N
authors.lastname: Zhao
authors.affiliation: Department of Chemistry, University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Kelly L
authors.initials: KL
authors.lastname: Sowers
authors.affiliation: Department of Chemistry, University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Todd D
authors.identifier: 0000-0002-4860-874X
authors.initials: TD
authors.lastname: Krauss
authors.affiliation: Department of Chemistry, University of Rochester , Rochester, New York 14627-0216, United States.
authors.forename: Daniel J
authors.identifier: 0000-0002-9552-3378
authors.initials: DJ
authors.lastname: Weix