title: An adolescent with large cell calcifying sertoli cell tumor of the testis and undiagnosed Carney Complex: A case report.
abstract: Carney Complex (CNC) is a rare autosomal dominant condition with characteristic clinical presentation, tumor development, and unique genetic mutation. We present a unique case and literature review of CNC in which two neoplasms characteristic of this complex were initially diagnosed through cytological fine needle aspirate specimens, leading to the identification of CNC, with subsequent surgical and cytogenetic confirmation. Diagn. Cytopathol. 2017;45:634-639. © 2017 Wiley Periodicals, Inc.
authors.affiliation: Department of Pathology, University of Alabama, Birmingham, Alabama, 35294.
authors.forename: Frida
authors.identifier: http://orcid.org/0000-0002-2825-485X
authors.initials: F
authors.lastname: Rosenblum
authors.affiliation: Department of Pathology, University of Alabama, Birmingham, Alabama, 35294.
authors.forename: Richard Gabriel
authors.initials: RG
authors.lastname: Koenig
authors.affiliation: Department of Pathology, University of Alabama, Birmingham, Alabama, 35294.
authors.forename: Fady M
authors.initials: FM
authors.lastname: Mikhail
authors.affiliation: Department of Pathology, University of Alabama, Birmingham, Alabama, 35294.
authors.forename: John R
authors.initials: JR
authors.lastname: Porterfield
authors.affiliation: Department of Pathology, University of Alabama, Birmingham, Alabama, 35294.
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Nix
authors.affiliation: Department of Pathology, University of Alabama, Birmingham, Alabama, 35294.
authors.forename: Isam-Eldin A
authors.initials: IA
authors.lastname: Eltoum
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D000315:Adrenalectomy; D056733:Carney Complex / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D054756:Cyclic AMP-Dependent Protein Kinase RIalpha Subunit / Q000235:genetics*; D015870:Gene Expression; D006801:Humans; D008297:Male; D009154:Mutation; D009392:Nephrectomy; D009919:Orchiectomy; D010180:Pancreatectomy; D012707:Sertoli Cell Tumor / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D013156:Splenectomy; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D013737:Testis / Q000473:pathology / Q000601:surgery; D055815:Young Adult
chemical_list: D054756:Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; C517834:PRKAR1A protein, human
keywords: Carney complex; cytology