title: Two new threitol orsellinates from a sea mud-derived fungus, Ascotricha sp. ZJ-M-5.
abstract: Two new d-threitol orsellinates (1-2) were isolated from the EtOAc extract of a sea mud-derived fungus, Ascotricha sp. ZJ-M-5, cultured in Czapek Dox broth. These two compounds featured in the symmetrical substitution of orsellinic acid or acetic acid, which was established on the basis of 1D and 2D NMR experiments. The characteristic optical rotations enabled the assignment of the absolute configuration.
authors.affiliation: a Key Laboratory of Structure-based Drug Design & Discovery, Ministry of Education , Shenyang Pharmaceutical University , Shenyang 110016 , China.|b School of Traditional Chinese Materia Media , Shenyang Pharmaceutical University , Shenyang 110016 , China.
authors.forename: Xiu-Mei
authors.initials: XM
authors.lastname: Xu
authors.affiliation: b School of Traditional Chinese Materia Media , Shenyang Pharmaceutical University , Shenyang 110016 , China.
authors.forename: Dan-Yi
authors.initials: DY
authors.lastname: Li
authors.affiliation: a Key Laboratory of Structure-based Drug Design & Discovery, Ministry of Education , Shenyang Pharmaceutical University , Shenyang 110016 , China.|b School of Traditional Chinese Materia Media , Shenyang Pharmaceutical University , Shenyang 110016 , China.
authors.forename: Hui-Ming
authors.initials: HM
authors.lastname: Hua
authors.affiliation: a Key Laboratory of Structure-based Drug Design & Discovery, Ministry of Education , Shenyang Pharmaceutical University , Shenyang 110016 , China.|b School of Traditional Chinese Materia Media , Shenyang Pharmaceutical University , Shenyang 110016 , China.
authors.forename: Zhan-Lin
authors.initials: ZL
authors.lastname: Li
authors.affiliation: c School of Pharmacy , Shenyang Pharmaceutical University , Shenyang 110016 , China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
mesh_terms: D019342:Acetic Acid / Q000737:chemistry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012118:Resorcinols / Q000737:chemistry / Q000302:isolation & purification*; D013402:Sugar Alcohols / Q000737:chemistry / Q000302:isolation & purification*; D013098:Xylariales / Q000737:chemistry*
chemical_list: C000621745:(2R,3R)-1,2,3,4-butanetetraol-1,4-diorsellinate; C000621746:(2R,3R)-14-diacetyl-1,2,3,4-butanetetraol-2,3-diorsellinate; D012118:Resorcinols; D013402:Sugar Alcohols; C501612:orsellinic acid; C003460:threitol; D019342:Acetic Acid
keywords: Ascotricha; Marine-derived fungus; d-threitol; orsellinic acid