title: Genome Sequencing Technologies and Nursing: What Are the Roles of Nurses and Nurse Scientists?
abstract: Advances in DNA sequencing technology have resulted in an abundance of personalized data with challenging clinical utility and meaning for clinicians. This wealth of data has potential to dramatically impact the quality of healthcare. Nurses are at the focal point in educating patients regarding relevant healthcare needs; therefore, an understanding of sequencing technology and utilizing these data are critical.
  
  
  
  The objective of this study was to explicate the role of nurses and nurse scientists as integral members of healthcare teams in improving understanding of DNA sequencing data and translational genomics for patients.
  
  
  
  A history of the nurse role in newborn screening is used as an exemplar.
  
  
  
  This study serves as an exemplar on how genome sequencing has been utilized in nursing science and incorporates linkages of other omics approaches used by nurses that are included in this special issue. This special issue showcased nurse scientists conducting multi-omic research from various methods, including targeted candidate genes, pharmacogenomics, proteomics, epigenomics, and the microbiome. From this vantage point, we provide an overview of the roles of nurse scientists in genome sequencing research and provide recommendations for the best utilization of nurses and nurse scientists related to genome sequencing.
authors.affiliation: Jacquelyn Y. Taylor, PhD, PNP-BC, RN, FAHA, FAAN, is Associate Professor and Associate Dean of Diversity and Inclusion, School of Nursing, Yale University, Orange, Connecticut. Michelle L. Wright, PhD, RN, is Assistant Research Professor, School of Nursing, Emory University, Atlanta, Georgia. She was a Postdoctoral Associate, School of Nursing, Yale University, Orange, Connecticut, at the time this work was completed Kathleen T. Hickey, EdD, FNP, ANP, FAHA, FAAN, is Associate Professor, School of Nursing, Columbia University, New York, New York. David E. Housman, PhD, is Virginia and D. K. Ludwig Scholar for Cancer Research and Professor of Biology, Department of Biology, Massachusetts Institute of Technology, Cambridge.
authors.forename: Jacquelyn Y
authors.initials: JY
authors.lastname: Taylor
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Wright
authors.forename: Kathleen T
authors.initials: KT
authors.lastname: Hickey
authors.forename: David E
authors.initials: DE
authors.lastname: Housman
mesh_terms: D005820:Genetic Testing; D015894:Genome, Human; D006801:Humans; D007231:Infant, Newborn; D017283:Neonatal Nursing / Q000379:methods*; D015997:Neonatal Screening / Q000451:nursing*; D024802:Nurse's Role; D015404:Nursing Methodology Research; D017422:Sequence Analysis, DNA