title: Long-term effects of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass for the treatment of morbid obesity: a monocentric prospective study with minimum follow-up of 5 years.
abstract: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are the most widely used bariatric procedures nowadays. The aim of this study was to compare long-term results on weight loss and comorbidities improvement for both procedures. A cohort of 304 consecutive patients underwent surgery in 2006-2009: 162 underwent LSG and 142 underwent LRYGB. The mean follow-up time was 75.8 ± 8.4 months (range 60-96). LSG showed greater effectiveness in percentage of excess weight loss (%EWL) at 180 days and at 1 year of follow-up. Instead, at 5th year follow-up LRYGB and LSG showed similar %EWL values (72.34 versus 70.26). LSG group showed a lack of weight loss in patients from 3 to 5 years after surgery, whereas LRYGB group patients maintained an effective weight loss during the entire follow-up period. In LSG group both length of stay and operative time were found to be shorter. LRYGB showed better effectiveness in type 2 diabetes mellitus (T2DM) resolution rate. None of the two techniques has proven to be clearly better than the other on a long-term follow-up analysis, except for the LRYGB better results in T2DM healing. According to our findings, in LSG Group after 3 years the weight remains stable.
authors.affiliation: General Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Rome, Italy. fed.perrone@gmail.com.
authors.forename: Federico
authors.initials: F
authors.lastname: Perrone
authors.affiliation: Psychiatric Unit, Department of System Medicine, University of Rome, Tor Vergata, Rome, Italy.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Bianciardi
authors.affiliation: University of Rome, Tor Vergata, Rome, Italy.
authors.forename: Simona
authors.initials: S
authors.lastname: Ippoliti
authors.affiliation: University of Rome, Tor Vergata, Rome, Italy.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Nardella
authors.affiliation: University of Rome, Tor Vergata, Rome, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Fabi
authors.affiliation: General Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Rome, Italy.|Bariatric Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Rome, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Gentileschi
mesh_terms: D000328:Adult; D050110:Bariatric Surgery / Q000379:methods; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods*; D015390:Gastric Bypass; D006801:Humans; D010535:Laparoscopy; D007902:Length of Stay; D009767:Obesity, Morbid / Q000601:surgery*; D011446:Prospective Studies; D015431:Weight Loss
keywords: Bariatric surgery; Gastric bypass; Obesity; Sleeve gastrectomy; Weight loss