title: PEGylated Perylenemonoimide-Dithienylethene for Super-Resolution Imaging of Liposomes.
abstract: We have designed and synthesized an amphiphilic photoswitchable fluorophore, PEGylated perylenemonoimide-dithienylethene (PEG-PMI-DTE), which exhibits evident bistable photochromism, fluorescence switching, and fatigue resistance. The fine nanostructures of liposomes can be observed directly under super-resolution fluorescent microscopy by aid of the amphiphilic photoswitchable fluorophore as a staining agent, with an optical resolution of 30 nm.
authors.affiliation: Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
authors.forename: Jun-Xia
authors.initials: JX
authors.lastname: Liu
authors.affiliation: Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Xin
authors.affiliation: Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
authors.forename: Chong
authors.identifier: http://orcid.org/0000-0003-0453-2496
authors.initials: C
authors.lastname: Li
authors.affiliation: Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
authors.forename: Nuo-Hua
authors.initials: NH
authors.lastname: Xie
authors.affiliation: Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
authors.forename: Wen-Liang
authors.initials: WL
authors.lastname: Gong
authors.affiliation: Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
authors.forename: Zhen-Li
authors.initials: ZL
authors.lastname: Huang
authors.affiliation: Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
authors.forename: Ming-Qiang
authors.identifier: http://orcid.org/0000-0002-8886-4166
authors.initials: MQ
authors.lastname: Zhu
mesh_terms: D007094:Imides / Q000737:chemistry*; D008081:Liposomes; D008856:Microscopy, Fluorescence; D010569:Perylene / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D007094:Imides; D008081:Liposomes; C532868:perylenemonoimide; D010569:Perylene
keywords: PEGylated; dithienylethene; liposomes; perylenemonoimide; super-resolution fluorescent microscopy