title: A new evolutionary optimization method for osteoporotic bone augmentation.
abstract: Bone augmentation is a preventative osteoporosis intervention, comprising the injection of bone cement into an osteoporotic bone. As injection of excessive amounts of bone cement may result into thermal necrosis of bone tissue or even embolism, the minimum cement volume required to achieve a predefined level of augmentation must be sought. To this end, the present paper introduces a new evolutionary optimization method, applicable to any osteoporotic bone. The method was numerically evaluated through a typical case of femoral augmentation and compared to another powerful optimization method. The results demonstrate the efficiency and low computational cost of the proposed method.
authors.affiliation: a School of Mechanical and Automotive Engineering , Kingston University , London , UK .
authors.forename: María E
authors.initials: ME
authors.lastname: Santana Artiles
authors.affiliation: a School of Mechanical and Automotive Engineering , Kingston University , London , UK .
authors.forename: Demetrios T
authors.initials: DT
authors.lastname: Venetsanos
mesh_terms: D000465:Algorithms; D001696:Biomechanical Phenomena / Q000187:drug effects; D001843:Bone Cements / Q000494:pharmacology; D055119:Elastic Modulus / Q000187:drug effects; D005269:Femur / Q000187:drug effects / Q000473:pathology*; D006801:Humans; D009336:Necrosis; D009716:Numerical Analysis, Computer-Assisted; D010024:Osteoporosis / Q000473:pathology*
chemical_list: D001843:Bone Cements
keywords: Bone augmentation; evolutionary method; femoroplasty; optimization; osteoporosis