title: [Leukopenia with unclear fever].
abstract: We report on a 77-year-old male patient with neutropenic fever as a result of a newly diagnosed agranulocytosis. The patient was taking metamizole, which is a well known cause of agranulocytosis. The diagnosis of metamizole-induced agranulocytosis as an underestimated side-effect of metamizole could be confirmed by a bone marrow biopsy. The bone marrow and the blood count recovered completely after stopping the therapy with metamizole and administration of granulocyte colony-stimulating factor (G-CSF).
authors.affiliation: Medizinische Klinik und Funktionsdiagnostik, Endoskopie, Sana Krankenhaus Gerresheim, Sana Kliniken Düsseldorf GmbH, Gräulinger Str. 120, 40625, Düsseldorf, Deutschland. SabineTheresia.Mayer@Sana.de.
authors.forename: S
authors.initials: S
authors.lastname: Mayer
authors.affiliation: Medizinische Klinik, Sana Krankenhaus Gerresheim, Sana Kliniken Düsseldorf GmbH, Gräulinger Str. 120, 40625, Düsseldorf, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Kündiger
authors.affiliation: Medizinische Klinik, Sana Krankenhaus Gerresheim, Sana Kliniken Düsseldorf GmbH, Gräulinger Str. 120, 40625, Düsseldorf, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Schrader
mesh_terms: D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced / Q000150:complications* / Q000188:drug therapy; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D004177:Dipyrone / Q000009:adverse effects; D064147:Febrile Neutropenia / Q000209:etiology*; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D008297:Male
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016179:Granulocyte Colony-Stimulating Factor; D004177:Dipyrone
keywords: Agranulocytosis; Biopsy, bone marrow; Dipyrone, adverse effects; Febrile neutropenia; Granulocyte colony-stimulating factor