title: The Effects of Acupuncture Stimulation for Brain Activation and Alcohol Abstinence Self-Efficacy: Functional MRI Study.
abstract: We attempted to investigate whether acupuncture stimulation at HT7 can have an effect on brain activation patterns and alcohol abstinence self-efficacy. Thirty-four right-handed healthy subjects were recruited for this study. They were randomly assigned into two groups: the HT7 (Shenmen) group and the LI5 (Yangxi) group. Acupuncture stimulation was performed using a block paradigm during fMRI scanning. Additionally, the Korean version of Alcohol Abstinence Self-Efficacy Scale (AASES) was used to determine the effect of acupuncture stimulation on self-efficacy to abstain from alcohol use. According to the result of fMRI group analysis, the activation induced by HT7 stimulation was found on the bilateral postcentral gyrus, inferior parietal lobule, inferior frontal gyrus, claustrum, insula, and anterior lobe of the cerebellum, as well as on the left posterior lobe of the cerebellum (p< 0.001, uncorrected). According to the AASES analysis, the interaction effect for gender and treatment was marginally significant (F(1, 30) = 4.152,p= 0.050). For female group, the simple main effect of treatment was significant (F(1, 11) = 8.040,p= 0.016), indicating that the mean change score was higher in the HT7 stimulation than in the LI5 stimulation. Therefore, our study has provided evidence to support that HT7 stimulation has a positive therapeutic effect on the alcohol-related diseases.
authors.affiliation: Department of Physiology, College of Oriental Medicine, Daegu Haany University, Daegu, Republic of Korea.
authors.forename: Chae Ha
authors.identifier: 0000-0002-4551-1600
authors.initials: CH
authors.lastname: Yang
authors.affiliation: Department of Anatomy and Histology, College of Oriental Medicine, Daegu Haany University, Daegu, Republic of Korea.
authors.forename: Seong Hun
authors.initials: SH
authors.lastname: Choi
authors.affiliation: Department of Medical Science, Graduate School, Daegu Haany University, Gyeongsan-si, Republic of Korea.
authors.forename: Ju Sang
authors.initials: JS
authors.lastname: Kim
authors.affiliation: KM Fundamental Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
authors.forename: Yeon Hee
authors.initials: YH
authors.lastname: Ryu
authors.affiliation: Department of Psychology, College of Social Sciences, Daegu University, Gyeongsan-si, Republic of Korea.
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Lim
authors.affiliation: Department of Secondary Special Education, College of Biomedical Science, Daegu Haany University, Gyeongsan-si, Republic of Korea.
authors.forename: Moon Seup
authors.initials: MS
authors.lastname: Kim
authors.affiliation: Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.
authors.forename: Jeong Woo
authors.initials: JW
authors.lastname: Sohn
authors.affiliation: Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.
authors.forename: Sung Suk
authors.initials: SS
authors.lastname: Oh
authors.affiliation: Department of Psychology, College of Social Sciences, Seoul National University, Seoul, Republic of Korea.
authors.forename: Cheongtag
authors.identifier: 0000-0002-9641-3912
authors.initials: C
authors.lastname: Kim
authors.affiliation: Department of Physical Therapy, College of Biomedical Science, Daegu Haany University, Gyeongsan-si, Republic of Korea.
authors.forename: Mi Young
authors.identifier: 0000-0002-8858-9360
authors.initials: MY
authors.lastname: Lee