title: A device for controlled jet injection of large volumes of liquid.
abstract: We present a needle-free jet injection device controllably actuated by a voice coil and capable of injecting up to 1.3 mL. This device is used to perform jet injections of ~900 μL into porcine tissue. This is the first time that delivery of such a large volume has been reported using an electronically controllable device. The controllability of this device is demonstrated with a series of ejections where the desired volume is ejected to within 1 % during an injection at a predetermined jet velocity.
authors.forename: James W
authors.initials: JW
authors.lastname: Mckeage
authors.forename: Bryan P
authors.initials: BP
authors.lastname: Ruddy
authors.forename: Poul M F
authors.initials: PM
authors.lastname: Nielsen
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Taberner
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems; D004867:Equipment Design; D007277:Injections, Jet / Q000295:instrumentation* / Q000379:methods; D009339:Needles; D013552:Swine