title: PREVALENCE OF CLEFT LIP AND PALATE IN GEORGIA.
abstract: Cleft lip and palate take significant place in congenital malformations. We aimed to study epidemiological peculiarities of these pathologies in Georgia for 2006-2015. We compared magnitude of its distribution with the data from 1981-1990. Prevalence of cleft lip and palate in Georgia in 2006-2015 was 0.95±0.04 per 1000 live births, while in 1981-1990- it was 1.05, i.e. in contrast to 1980's frequency of these pathological conditions decreased to some extent. Distribution of cleft lip and palate varies across the country regions. The most intensive spread has been observed in Mtskheta-Mtianeti region, where prevalence composed 2.28/1000. In the rest of the regions frequency of these pathologies is significantly lower. For instance, in Kakheti the rate is equal to 1,87/1000, in Kvemo Kartli - 1.56/1000, in Shida Kartli - 1.55/1000. In the rest of the regions prevalence rate is lower than the country average. It should be noted that in Tbilisi the rate is as low as 0.80/1000. The lowest level has been reported in Guria - 0.56/1000. Currently cleft lip with palate is the most frequently occurring anomaly in Georgia accounting for 39.8% of all congenital malformations. Cleft lip alone ranks the second - 36.1%, followed by cleft palate (24.1%). These pathologies are more frequent in boys than in girls. 60.3% of the cases are reported in males, in contrast to girls - 39.7% (p<0.01). Usually, cleft palate is the most common among girls, but in our case, it had higher prevalence among boys, 53.6% vs. 46,4%. Thus cleft lip and palate distribution in Georgia is characterized by epidemiological peculiarities, which should be considered in implementation of preventive measures.
authors.affiliation: Tbilisi State Medical University, Department of Surgery Direction of Child and Adolescent Stomatology (Dentistry) and Prophylactics of Stomatological (Dental) Diseases, Department of Epidemiology and Biostatistics, Direction of Public Health, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Chincharadze
authors.affiliation: Tbilisi State Medical University, Department of Surgery Direction of Child and Adolescent Stomatology (Dentistry) and Prophylactics of Stomatological (Dental) Diseases, Department of Epidemiology and Biostatistics, Direction of Public Health, Georgia.
authors.forename: Z
authors.initials: Z
authors.lastname: Vadachkoria
authors.affiliation: Tbilisi State Medical University, Department of Surgery Direction of Child and Adolescent Stomatology (Dentistry) and Prophylactics of Stomatological (Dental) Diseases, Department of Epidemiology and Biostatistics, Direction of Public Health, Georgia.
authors.forename: I
authors.initials: I
authors.lastname: Mchedlishvili
mesh_terms: D002971:Cleft Lip / Q000453:epidemiology*; D002972:Cleft Palate / Q000453:epidemiology*; D005260:Female; D005846:Georgia (Republic); D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015995:Prevalence