title: Explanatory Models and Medication Adherence in Patients with Depression in South India.
abstract: BACKGROUND
  Conceptualization of depression may have bearing on treatment seeking. It may affect adherence behaviour of the patients.
  
  
  OBJECTIVE
  To find out the explanatory models and their relationship with socio-demographic variables and medication adherence in patients with depression.
  
  
  METHODS
  Fifty-eight consecutive patients with depression in remission were recruited as per selection criteria. Socio-demographic details were collected. Patients were assessed using Mental Distress Explanatory Model Questionnaire (MDEMQ) and Morisky Medication Adherence Scale (MMAS).
  
  
  RESULTS
  Significant scores were observed in all dimensions of explanatory models. In the Mann-Whitney U test the patient's marital status (MU=113.500, p=0.05, sig≤0.05, 2-tailed), and family history of mental illness (MU=165.5, p=0.03, sig≤0.05, 2-tailed) had a statistically significant group difference in the score of MDEMQ. In linear regression analysis, four predictors (MDEMQ subscales Stress, Western physiology, Non-Western physiology and Supernatural) had significantly predicted the value of MMAS (R2=0.937, f=153.558, p<0.001).
  
  
  CONCLUSIONS
  Findings of this study suggested that patients with depression harbor multidimensional explanatory model. The levels of explanatory models are inversely associated with levels of medication adherence.
authors.affiliation: Associate Professor, Department of Psychiatry, JSS Medical College and Hospital , Mysore, Karnataka, India .
authors.forename: Dushad
authors.initials: D
authors.lastname: Ram
authors.affiliation: Assistant Professor, Department of Medicine, JSS Medical College and Hospital , Mysore, Karnataka, India .
authors.forename: Adarsh Lakkur
authors.initials: AL
authors.lastname: Siddappa
authors.affiliation: Professor, Department of Psychiatry, JSS Medical College and Hospital , Mysore, Karnataka, India .
authors.forename: Rajesh
authors.initials: R
authors.lastname: Raman
authors.affiliation: Professor, Department of Medicine, JSS Medical College and Hospital , Mysore, Karnataka, India .
authors.forename: Basavana Gowdappa
authors.initials: BG
authors.lastname: Hattur
keywords: Concept formation; Explanatory model; Major depressive disorder