title: Screening and Preventive Strategies in Esophagogastric Cancer.
abstract: Gastric adenocarcinoma, esophageal adenocarcinoma, and esophageal squamous cell carcinoma are among the most prevalent and deadly of malignancies worldwide. Screening and prevention programs will be critical to finally improving outcomes in these diseases. For gastric adenocarcinoma, screening in high-risk populations has significantly reduced mortality. More research is needed on screening high-risk individuals in low-risk populations. For esophageal adenocarcinoma, work is needed to develop efficient and effective techniques in mass screening programs. For most Western populations, current screening is not cost effective. Avoiding environmental risk factors is critical to reducing the incidence of this deadly illness.
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, 200 2nd St. SW, Rochester, MN 55905, USA.
authors.forename: Liam
authors.initials: L
authors.lastname: Zakko
authors.affiliation: Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street Northwest, Rochester, MN, USA.
authors.forename: Lori
authors.initials: L
authors.lastname: Lutzke
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, 200 2nd St. SW, Rochester, MN 55905, USA. Electronic address: wang.kenneth@mayo.edu.
authors.forename: Kenneth K
authors.initials: KK
authors.lastname: Wang
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000517:prevention & control*; D001471:Barrett Esophagus; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000517:prevention & control*; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000517:prevention & control*; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000517:prevention & control
keywords: Barrett esophagus; Esophageal adenocarcinoma; Esophageal squamous cell carcinoma; Gastric adenocarcinoma; Prevention; Screening