title: Drugging the undruggable: targeting challenging E3 ligases for personalized medicine.
authors.affiliation: Facultat de Farmàcia i Ciències de l'Alimentació, Institut de Biomedicina (IBUB), Universitat de Barcelona. Av. Joan XXIII 27-31, 08028 Barcelona, Spain.
authors.forename: Carles
authors.initials: C
authors.lastname: Galdeano
mesh_terms: D055808:Drug Discovery; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008024:Ligands; D057285:Precision Medicine; D044767:Ubiquitin-Protein Ligases / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D008024:Ligands; D044767:Ubiquitin-Protein Ligases
keywords: E3 ligases; personalized medicine; protein–protein interactions; undruggable targets