title: JA-Ile-macrolactones uncouple growth and defense in wild tobacco.
abstract: Small molecules capable of uncoupling growth-defense in plants are currently not known. In this study, for the first time, semi-synthetic analogues of the phytohormone JA-Ile are employed to uncouple growth and defense responses in wild tobacco. The JA-Ile analogues are easily synthesized from inexpensive substrates via olefin metathesis.
authors.affiliation: Department of Bioorganic Chemistry, Max Planck Institute für chemische Ökologie, 07745 Jena, Germany. gjimenez-aleman@ice.mpg.de boland@ice.mpg.de.
authors.forename: Guillermo H
authors.initials: GH
authors.lastname: Jimenez-Aleman
authors.forename: Ricardo A R
authors.initials: RAR
authors.lastname: Machado
authors.forename: Ian T
authors.initials: IT
authors.lastname: Baldwin
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Boland
mesh_terms: D000475:Alkenes / Q000737:chemistry; D003517:Cyclopentanes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D007532:Isoleucine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D007783:Lactones / Q000737:chemistry*; D014026:Nicotiana / Q000187:drug effects* / Q000254:growth & development* / Q000276:immunology
chemical_list: D000475:Alkenes; D003517:Cyclopentanes; D007783:Lactones; C532883:jasmonoyl-isoleucine; D007532:Isoleucine