title: Secondary gastric cancer malignancies following a breast cancer diagnosis: A population-based analysis.
abstract: OBJECTIVE
  To quantify the population-risk of developing gastric cancer (GC) following breast cancer (BC).
  
  
  METHODS
  GC incidence following a ductal or lobular BC were separately compared to incidence in the general United States population using SEER data.
  
  
  RESULTS
  GC rates were similar to the general population for ductal BC. Women aged 35-75 with lobular BC had a significantly higher incidence of GC; women aged 40-44 had the highest risk.
  
  
  CONCLUSIONS
  The risk of secondary GC is high among young women diagnosed with lobular BC. More studies investigating the etiology and prevalence of familial GC syndromes at the population-level are needed.
authors.affiliation: Department of Public Health Sciences, Queen's University, Canada; Sunnybrook Research Institute, Toronto, Canada.
authors.forename: Alyson L
authors.initials: AL
authors.lastname: Mahar
authors.affiliation: Department of Surgery, University of Toronto, Canada; Sunnybrook Research Institute, Toronto, Canada.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Kagedan
authors.affiliation: Department of Surgery, University of Toronto, Canada; Sunnybrook Research Institute, Toronto, Canada; Division of General Surgery, Sunnybrook Health Sciences Centre - Odette Cancer Centre, Toronto, Canada.
authors.forename: Julie
authors.initials: J
authors.lastname: Hallet
authors.affiliation: Department of Surgery, University of Toronto, Canada; Sunnybrook Research Institute, Toronto, Canada; Division of General Surgery, Sunnybrook Health Sciences Centre - Odette Cancer Centre, Toronto, Canada. Electronic address: natalie.coburn@sunnybrook.ca.
authors.forename: Natalie G
authors.initials: NG
authors.lastname: Coburn
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000453:epidemiology* / Q000473:pathology; D018275:Carcinoma, Lobular / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology* / Q000473:pathology; D012307:Risk Factors; D018426:SEER Program; D013274:Stomach Neoplasms / Q000453:epidemiology* / Q000473:pathology; D014481:United States / Q000453:epidemiology
keywords: Gastric cancer; Hereditary cancer syndromes