title: Polyelectrolyte Layer-by-Layer Assembly on Organic Electrochemical Transistors.
abstract: Oppositely charged polyelectrolyte multilayers (PEMs) were built up in a layer-by-layer (LbL) assembly on top of the conducting polymer channel of an organic electrochemical transistor (OECT), aiming to combine the advantages of well-established PEMs with a high performance electronic transducer. The multilayered film is a model system to investigate the impact of biofunctionalization on the operation of OECTs comprising a poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT:PSS) film as the electrically active layer. Understanding the mechanism of ion injection into the channel that is in direct contact with charged polymer films provides useful insights for novel biosensing applications such as nucleic acid sensing. Moreover, LbL is demonstrated to be a versatile electrode modification tool enabling tailored surface features in terms of thickness, softness, roughness, and charge. LbL assemblies built up on top of conducting polymers will aid the design of new bioelectronic platforms for drug delivery, tissue engineering, and medical diagnostics.
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: Anna-Maria
authors.initials: AM
authors.lastname: Pappa
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.|Biological and Environmental Science and Engineering, King Abdullah University of Science and Technology (KAUST) , Thuwal 23955-6900, Kingdom of Saudi Arabia.
authors.forename: Sahika
authors.initials: S
authors.lastname: Inal
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: Kirsty
authors.initials: K
authors.lastname: Roy
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: Charalampos
authors.initials: C
authors.lastname: Pitsalidis
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: Adel
authors.initials: A
authors.lastname: Hama
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: Jolien
authors.initials: J
authors.lastname: Pas
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: George G
authors.initials: GG
authors.lastname: Malliaras
authors.affiliation: Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC , 13541 Gardanne, France.
authors.forename: Roisin M
authors.initials: RM
authors.lastname: Owens
mesh_terms: D016503:Drug Delivery Systems; D004566:Electrodes; D000071228:Polyelectrolytes / Q000737:chemistry*
chemical_list: D000071228:Polyelectrolytes
keywords: conducting polymer; layer-by-layer; nucleic acid; organic transistor; polyelectrolyte