title: Paraoxonase 1 - an Update of the Antioxidant Properties of High- Density Lipoproteins.
abstract: Paraoxonase 1 (PON1) belongs to a family of enzymes with related functions, being the best studied member. PON1 is a HDL-associated protein of which function is to protect LDL particles from oxidative modifications. The status of PON1 is influenced by different genetic, life style and dietary factors. This short review is aimed to present some new aspects regarding the antioxidant properties of PON1 with emphasis on the influence exerted by different factors. Also, a special attention is paid to the relationship between PON1 and low- and high-density lipoproteins in the context of atherosclerosis which affects the endothelial cells.
authors.affiliation: Department of Organic Chemistry "C.D. Nenitescu", Faculty of Applied Chemistry and Science of Materials, Polytechnic University, Bucharest, Romania.
authors.forename: Bogdan Nicolae
authors.initials: BN
authors.lastname: Manolescu
authors.affiliation: Department of Functional Sciences, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy Bucharest, Romania.
authors.forename: Carmina
authors.initials: C
authors.lastname: Busu
authors.affiliation: Department III - Medical Dentistry, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Daniela
authors.initials: D
authors.lastname: Badita
authors.affiliation: Department of Obstetrics and Gynecologie, "St. Pantelimon" Emergency Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Ruxandra
authors.initials: R
authors.lastname: Stanculescu
authors.affiliation: Department of Rehabilitation, Elias Emergency Hospital, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Mihai
authors.initials: M
authors.lastname: Berteanu