title: Efficacy and safety of NBCA (n-butyl-2-cyanoacrylate) medical adhesive for patch fixation in totally extraperitoneal prosthesis (TEP): a prospective, randomized, controlled trial.
abstract: To evaluate the effectiveness of n-butyl-2-cyanoacrylate (NBCA) medical adhesive for mesh fixation in totally extraperitoneal prosthesis (TEP) for inguinal hernia repair.
  
  
  
  A total of 160 patients with primary unilateral inguinal hernia were assigned randomly to receive TEP using NBCA medical adhesive for patch fixation (experimental group) and without patch fixation (control group). We evaluated operation time, visual analogue scale (VAS) pain score 24 h after surgery, postoperative duration of stay, hospital costs, postoperative complications, and hernia recurrence.
  
  
  
  A total of 160 cases were operated successfully. There was no significant difference in operation time, VAS pain score 24h after surgery, postoperative duration of stay, hospital costs and postoperative complications between the groups (p > 0.05). Hernia recurrence occurred in 4 cases of the control group. None of the experimental group had a significant difference (p < 0.05).
  
  
  
  The use of NBCA medical adhesive for patch fixation in TEP is effective and safe.
authors.affiliation: Department of Hernia and Abdominal Wall Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. chenjie20160628@163.com.
authors.forename: Y-M
authors.initials: YM
authors.lastname: Shen
authors.forename: Y-T
authors.initials: YT
authors.lastname: Liu
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.forename: L
authors.initials: L
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D004659:Enbucrilate / Q000627:therapeutic use*; D005260:Female; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy; D011183:Postoperative Complications / Q000601:surgery; D011446:Prospective Studies; D019736:Prostheses and Implants; D012008:Recurrence; D013526:Surgical Mesh; D014014:Tissue Adhesives / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D014014:Tissue Adhesives; D004659:Enbucrilate