title: [FEATURES OF THE TREATMENT OF THE SPINE IN RHEUMATOID ARTHRITIS].
abstract: Rheumatoid arthritis (RA) refers to the most common inflammatory joint disease, which can lead to persistent disability and early mortality of patients, and one of the manifestations of RA is a frequent lesion of the spine, which significantly affects the quality of life of these patients.
  
  
  OBJECTIVE
  To evaluate spine lesion in patients with different types of current RA and factors that determine it.
  
  
  METHODS
  Under the supervision of the RA patient 131 was aged 18 to 79 years (mean 45 years) among them was 18% male and 82% female. Duration of disease was 10 years, I radiographic arthritis stage is set to 8% of cases, II - 38%, III - 35%, IV - 19%, by rheumatoid factor seropositivity was observed in 77% of patients studied, and by the presence of antibodies against cyclic citrullin peptide - y ¾. Extra-articular (systemic) form of the disease occurred in 43% of cases, systemic osteoporosis - 67%.
  
  
  RESULTS
  lesions of the spine in the form of osteochondrosis and spondyloarthrosis observed at ½ of the number of RA patients, and clinically overt occurs in 35% of cases, which is directly related to patient age, involving in the process of wrist, elbow and hip joints, the presence of systemic osteoporosis and tendovaginitis, sensory and motor disorders due to peripheral neuropathy. Frequency ratio of mechanical, disfixtional, disgemic and inflammatory pain in the spine in RA is a 1: 2: 6: 14. Radiographs revealed ossification of the outer layers of the intervertebral discs and the formation sindesmofitov and spondylodiscitis. Involvement of joints is characterized by vagueness of the articular surfaces and narrowing gaps. Vertebral pathology affects heart disease symptoms (changes in electrical conductivity, the size of cameras, the left ventricular diastolic function), autonomic changes and severity of neuropathy and predictors are blood levels of rheumatoid factor and C-reactive protein. Due to the nature of spinal lesions in rheumatoid arthritis has been proposed a scheme of treatment with Actemra, Orcerin, Zoledro-Denk.
  
  
  CONCLUSIONS
  Spondylopathies is a frequent manifestation of RA, is interconnected with many clinical and laboratory signs of the disease, and in the future early detection of spondylopathies in the patients with active RA will be useful for timely rehabilitation.
authors.affiliation: M. Gorky Donetsk National Medical University, Ukraine; Medical Centre Ukrgeorgmedical, Batumi, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Selezneva
authors.affiliation: M. Gorky Donetsk National Medical University, Ukraine; Medical Centre Ukrgeorgmedical, Batumi, Georgia.
authors.forename: O
authors.initials: O
authors.lastname: Sinyachenko
authors.affiliation: M. Gorky Donetsk National Medical University, Ukraine; Medical Centre Ukrgeorgmedical, Batumi, Georgia.
authors.forename: А
authors.initials: А
authors.lastname: Zabara
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D055815:Young Adult