title: The Pharmaceutical Industry in 2016. An Analysis of FDA Drug Approvals from a Perspective of the Molecule Type.
abstract: This is an analysis from a chemical point of view of the 22 drugs accepted by the FDA during 2016. The different drugs from the 2016 "harvest" have been classified according to their chemical structure: antibodies; TIDES (oligonucleotides and peptides); amino acids and natural products; drug combination; and small molecules.
authors.affiliation: School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, 4001 Durban, South Africa. garciadelatorreb@ukzn.ac.za.
authors.forename: Beatriz G de la
authors.initials: BG
authors.lastname: Torre
authors.affiliation: School of Chemistry, University of KwaZulu-Natal, 4001 Durban, South Africa. albericio@ukzn.ac.za.|CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, University of Barcelona, 08028 Barcelona, Spain. albericio@ukzn.ac.za.|Department of Organic Chemistry, University of Barcelona, 08028 Barcelona, Spain. albericio@ukzn.ac.za.
authors.forename: Fernando
authors.initials: F
authors.lastname: Albericio
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D000906:Antibodies / Q000737:chemistry; D001688:Biological Products / Q000737:chemistry*; D062313:Databases, Pharmaceutical / Q000706:statistics & numerical data; D017277:Drug Approval; D004345:Drug Industry; D006801:Humans; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D054852:Small Molecule Libraries / Q000737:chemistry; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000596:Amino Acids; D000906:Antibodies; D001688:Biological Products; D004364:Pharmaceutical Preparations; D054852:Small Molecule Libraries
keywords: API; biologics; chemical entities; drug discovery; peptide; small molecules