title: Regional Cerebral Blood Flow SPECT and MRI in Logopenic Variant Primary Progressive Aphasia.
abstract: We report a 61-year-old woman who presented because of gradually progressive speech disorders. MRI scan revealed left temporal lobe atrophy with ex vacuo dilatation of the temporal horn and atrophy of the left inferior frontal gyrus and the left inferior parietal lobe. These findings in brain perfusion SPECT corresponded to a generalized hypoperfusion of the left hemisphere, particularly prominent on the rear parietal cortex and the temporal lobe. After taking into consideration the clinical presentation and imaging findings on MRI and SPECT, the diagnosis of the logopenic variant of primary progressive aphasia was finally reached.
authors.affiliation: From the *Department of Neurology, †Department of Nuclear Medicine, ‡Neurosurgical Research Institute, School of Medicine, and §Department of Radiology, Medical School, University of Ioannina, Ioannina, Greece.
authors.forename: Aristeidis H
authors.initials: AH
authors.lastname: Katsanos
authors.forename: Spyridon
authors.initials: S
authors.lastname: Tsiouris
authors.forename: Chrissa
authors.initials: C
authors.lastname: Sioka
authors.forename: Anastasia
authors.initials: A
authors.lastname: Zikou
authors.forename: Andreas
authors.initials: A
authors.lastname: Fotopoulos
mesh_terms: D018888:Aphasia, Primary Progressive / Q000000981:diagnostic imaging*; D001284:Atrophy; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013702:Temporal Lobe / Q000000981:diagnostic imaging* / Q000473:pathology; D015899:Tomography, Emission-Computed, Single-Photon