title: New Coumarinyl Ethers in Daphne oleoides Schreb. Collected from Sardinia Island.
abstract: The phytochemical analysis of the ethanolic extract obtained from D. oleoides collected from Sardinia Island allowed the isolation of several new constituents for the species (3, 8, and 9) together with two new coumarinyl ethers (1 and 2) besides the chemotaxonomic markers of the Daphne genus (4 - 7 and 10) which are also known to possess interesting biological activities. The structure of the new compounds were elucidated by extensive spectroscopic and spectrometric analyses. The identification of these compounds gives an experimental evidence of the variability in the secondary metabolites pattern owned by populations growing in restricted area in respect to populations not confined by geographical barrier.
authors.affiliation: Dipartimento di Chimica, 'Sapienza' Università di Roma, Piazzale Aldo Moro 5, IT-00185, Rome.
authors.forename: Alessandro
authors.identifier: http://orcid.org/0000-0003-1492-6739
authors.initials: A
authors.lastname: Venditti
authors.affiliation: Dipartimento di Scienze della Vita e dell'Ambiente, Università degli Studi di Cagliari, Via Sant'Ignazio da Laconi 13, IT-09123, Cagliari.
authors.forename: Cinzia
authors.initials: C
authors.lastname: Sanna
authors.affiliation: Dipartimento di Chimica, 'Sapienza' Università di Roma, Piazzale Aldo Moro 5, IT-00185, Rome.
authors.forename: Lorenzo M
authors.initials: LM
authors.lastname: Lorenzetti
authors.affiliation: Co.S.Me.Se., Consorzio per lo Studio dei Metaboliti Secondari, via Sant'Ignazio da Laconi 13, IT-09123, Cagliari.
authors.forename: Mauro
authors.initials: M
authors.lastname: Ballero
authors.affiliation: Dipartimento di Chimica, 'Sapienza' Università di Roma, Piazzale Aldo Moro 5, IT-00185, Rome.
authors.forename: Armandodoriano
authors.initials: A
authors.lastname: Bianco
mesh_terms: D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D032364:Daphne / Q000737:chemistry*; D000431:Ethanol; D004987:Ethers / Q000737:chemistry / Q000302:isolation & purification*; D007558:Italy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D064210:Secondary Metabolism; D013057:Spectrum Analysis
chemical_list: D003374:Coumarins; D004987:Ethers; D010936:Plant Extracts; D000431:Ethanol
keywords: 
  Daphne oleoides
  ; Chemotaxonomy; Coumarins; Secondary metabolites; Structure elucidation