title: Wake-Up Stroke: Current Understanding.
abstract: Patients with wake-up strokes account for approximately 1 in 5 individuals presenting with an acute ischemic stroke. However, they are commonly excluded from acute stroke treatment. This article reviews the current understanding of wake-up strokes. A comparison of wake-up and awake-onset strokes demonstrated that they are physiologically, clinically, and radiologically similar. Use of advanced CT and MRI techniques may help extend acute stroke treatment options to patients with wake-up stroke.
authors.affiliation: Department of Neurology and Neurological Sciences, Stanford University Medical Centre, Stanford, CA.
authors.forename: Jenny P
authors.initials: JP
authors.lastname: Tsai
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Albers
mesh_terms: D006801:Humans; D020521:Stroke / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D014851:Wakefulness / Q000502:physiology*