title: Relation of visual creative imagery manipulation to resting-state brain oscillations.
abstract: Visual creative imagery (VCI) manipulation is the key component of visual creativity; however, it remains largely unclear how it occurs in the brain. The present study investigated the brain neural response to VCI manipulation and its relation to intrinsic brain activity. We collected functional magnetic resonance imaging (fMRI) datasets related to a VCI task and a control task as well as pre- and post-task resting states in sequential sessions. A general linear model (GLM) was subsequently used to assess the specific activation of the VCI task compared with the control task. The changes in brain oscillation amplitudes across the pre-, on-, and post-task states were measured to investigate the modulation of the VCI task. Furthermore, we applied a Granger causal analysis (GCA) to demonstrate the dynamic neural interactions that underlie the modulation effect. We determined that the VCI task specifically activated the left inferior frontal gyrus pars triangularis (IFGtriang) and the right superior frontal gyrus (SFG), as well as the temporoparietal areas, including the left inferior temporal gyrus, right precuneus, and bilateral superior parietal gyrus. Furthermore, the VCI task modulated the intrinsic brain activity of the right IFGtriang (0.01-0.08 Hz) and the left caudate nucleus (0.2-0.25 Hz). Importantly, an inhibitory effect (negative) may exist from the left SFG to the right IFGtriang in the on-VCI task state, in the frequency of 0.01-0.08 Hz, whereas this effect shifted to an excitatory effect (positive) in the subsequent post-task resting state. Taken together, the present findings provide experimental evidence for the existence of a common mechanism that governs the brain activity of many regions at resting state and whose neural activity may engage during the VCI manipulation task, which may facilitate an understanding of the neural substrate of visual creativity.
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Yuxuan
authors.initials: Y
authors.lastname: Cai
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Delong
authors.initials: D
authors.lastname: Zhang
authors.affiliation: College of Education, Guangdong Polytechnic Normal University, Guangdong Sheng, 510640, China.
authors.forename: Bishan
authors.initials: B
authors.lastname: Liang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Zengjian
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Junchao
authors.initials: J
authors.lastname: Li
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Zhenni
authors.initials: Z
authors.lastname: Gao
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Mengxia
authors.initials: M
authors.lastname: Gao
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Song
authors.initials: S
authors.lastname: Chang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China.
authors.forename: Bingqing
authors.initials: B
authors.lastname: Jiao
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China. ruiwang.huang@gmail.com.
authors.forename: Ruiwang
authors.initials: R
authors.lastname: Huang
authors.affiliation: Center for the Study of Applied Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, 510631, China. lium@scnu.edu.cn.
authors.forename: Ming
authors.initials: M
authors.lastname: Liu
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D003405:Creativity; D005260:Female; D006801:Humans; D007092:Imagination / Q000502:physiology*; D016014:Linear Models; D008279:Magnetic Resonance Imaging; D008297:Male; D009434:Neural Pathways / Q000000981:diagnostic imaging / Q000502:physiology; D009483:Neuropsychological Tests; D012146:Rest; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult
keywords: Brain intrinsic activity; Functional magnetic resonance imaging (fMRI); General linear model (GLM); Left-over-right inhibition; Visual creative imagery (VCI)