title: Comparison of Axial Length, Corneal Curvature, and Anterior Chamber Depth Measurements of 2 Recently Introduced Devices to a Known Biometer.
abstract: OBJECTIVE
  Evaluate agreement and repeatability of axial length (AL), corneal curvature, and anterior chamber depth measurements of 2 new devices, 1 using Scheimpflug technology combined with partial coherence interferometry (Pentacam AXL) and 1 using swept-source optical coherence tomography (IOL Master 700) to a widely used optical biometer (IOL Master 500).
  
  
  METHODS
  Prospective, instrument reliability analysis.
  
  
  METHODS
  This study was conducted in the Department of Ophthalmology at Goethe-University, Frankfurt, Germany. Seventy-nine eyes in 79 patients were measured with the IOL Master 500, the IOL Master 700, and with the Pentacam AXL. All eyes were measured twice with each device. The results were statistically compared using Bland-Altman plots. Outcome measures included AL, corneal curvature, and the measurement of anterior chamber depth.
  
  
  RESULTS
  The Bland-Altman analysis of axial length measurements with the IOL Master 500 and IOL Master 700 showed a mean difference of 0.008 mm between the 2 devices, with a coefficient of repeatability (COR) of 0.044 (P = .05). For measurements with the IOL Master 500 and Pentacam AXL, a mean difference of 0.026 mm and COR of 0.055 (P = .75) was found. For measurements with Pentacam AXL and IOL Master 700, a mean difference of -0.019 mm and COR of 0.052 (P = .06) was found. In terms of repeatability, there was no significant difference in measurement of any variable with any device. Vector analysis showed no significant difference for corneal astigmatism measurements (P = .84).
  
  
  CONCLUSIONS
  There was no statistically significant difference in compared biometric parameters performed with all 3 devices.
authors.affiliation: Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Shajari
authors.affiliation: Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
authors.forename: Carla
authors.initials: C
authors.lastname: Cremonese
authors.affiliation: Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
authors.forename: Kerstin
authors.initials: K
authors.lastname: Petermann
authors.affiliation: Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Singh
authors.affiliation: Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Müller
authors.affiliation: Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany. Electronic address: kohnen@em.uni-frankfurt.de.
authors.forename: Thomas
authors.initials: T
authors.lastname: Kohnen
mesh_terms: D000867:Anterior Chamber / Q000000981:diagnostic imaging*; D001251:Astigmatism / Q000175:diagnosis*; D058452:Axial Length, Eye / Q000000981:diagnostic imaging*; D001699:Biometry / Q000379:methods*; D003315:Cornea / Q000000981:diagnostic imaging*; D004867:Equipment Design; D006801:Humans; D007368:Interferometry / Q000295:instrumentation*; D011446:Prospective Studies; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000295:instrumentation*