title: Pericytes or Mesenchymal Stem Cells: Is That the Question?
abstract: For almost a decade, mesenchymal stem cells (MSCs) were believed to reside as perivascular cells in vivo. In this issue of Cell Stem Cell, Guimarães-Camboa et al. (2017) challenge this idea and use lineage tracing to demonstrate that perivascular cells do not behave as tissue-specific progenitors in various organs, despite showing MSC potential in vitro.
authors.affiliation: Integrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin.
authors.forename: Elena
authors.initials: E
authors.lastname: Cano
authors.affiliation: Integrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin.
authors.forename: Véronique
authors.initials: V
authors.lastname: Gebala
authors.affiliation: Integrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin; Berlin Institute of Health (BIH), Kapelle-Ufer 2, 10117 Berlin, Germany; Vascular Patterning Laboratory, Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address: holger.gerhardt@mdc-berlin.de.
authors.forename: Holger
authors.initials: H
authors.lastname: Gerhardt
mesh_terms: D002454:Cell Differentiation; D059630:Mesenchymal Stem Cells; D020286:Pericytes