title: New Therapeutic Approach to Treat Allergic Rhinitis & Bronchial Asthma, Considering These Two as One United Airway Disease.
abstract: The relationship between allergic rhinitis and asthma is now established, and most of the clinical, epidemiological and biological data recommend integrated management. This review discusses rhinosinusitis as a co-morbid condition, a precipitating or triggering condition, and an epiphenomenon as an integrated part of the disease. A better understanding and a more pragmatic method of diagnosis and management is needed using cost-effective long-term strategies. Allergic Rhinitis, though a non-life threatening disease, its pathogenesis reveals that Bronchial Asthma also develops by the same aetiopathogenesis. The United airway disease hypothesis proposes that the upper & lower airway diseases are both manifestations of a single inflammatory process and studies have already proved it. Allergic Rhinitis when once develops if not treated vigorously, can later turn up to Asthma. As chronic inflammation is the central process which is actually continuously changing pathologically the lower respiratory tract & helping to develop Bronchial Asthma. The conventional therapies for Allergic Rhinitis such as antihistamines & decongestants are only symptom relievers, to stop the ongoing pathogenesis of Bronchial Asthma to develop it, the chronic inflammatory process should have to be stopped. This can be done by corticosteroid nasal sprays. Also Asthma with Rhinitis is better controlled by them. Even Bronchial Asthma treatment should be started with inhaler corticosteroid therapy rather than getting it after intermittent use of only bronchodilators (salbutamol) only.
authors.affiliation: Professor Mohammed Atiqur Rahman, Professor, Department of Respiratory Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail: m_a_rahman88@yahoo.com.
authors.forename: M A
authors.initials: MA
authors.lastname: Rahman
authors.forename: R
authors.initials: R
authors.lastname: Chakraborty
authors.forename: K R
authors.initials: KR
authors.lastname: Ferdousi
authors.forename: A
authors.initials: A
authors.lastname: Alam
authors.forename: M K
authors.initials: MK
authors.lastname: Chowdhury
authors.forename: B K
authors.initials: BK
authors.lastname: Paul
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D001249:Asthma / Q000150:complications / Q000628:therapy; D006801:Humans; D065631:Rhinitis, Allergic / Q000150:complications / Q000628:therapy; D012852:Sinusitis / Q000150:complications / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones