title: Drug-Coated Balloons: Current Outcomes and Future Directions.
abstract: Paclitaxel-coated drug-coated balloons have significantly improved short-term and mid-term clinical outcomes in patients with symptomatic femoropopliteal peripheral artery disease. However, long-term results are awaited. Furthermore, the clinical success of drug-coated balloons in the infrapopliteal peripheral arteries has been more modest and overall similar to traditional balloon angioplasty, and remains an area of unmet clinical need. This article provides an overview of the clinical evidence for paclitaxel-coated balloons in the femoropopliteal and infrapopliteal peripheral artery distributions and future directions in this area.
authors.affiliation: Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA.
authors.forename: Ananya
authors.initials: A
authors.lastname: Kondapalli
authors.affiliation: Division of Cardiology, Department of Medicine, Veterans Affairs North Texas Health Care System, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA.
authors.forename: Barbara A
authors.initials: BA
authors.lastname: Danek
authors.affiliation: Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA; Division of Cardiology, Department of Medicine, Veterans Affairs North Texas Health Care System, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA.
authors.forename: Houman
authors.initials: H
authors.lastname: Khalili
authors.affiliation: Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA; Division of Cardiology, Department of Medicine, Veterans Affairs North Texas Health Care System, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA.
authors.forename: Haekyung
authors.initials: H
authors.lastname: Jeon-Slaughter
authors.affiliation: Division of Cardiology, Department of Medicine, University of Texas Southwestern Medical Center, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA; Division of Cardiology, Department of Medicine, Veterans Affairs North Texas Health Care System, 4500 South Lancaster Road (111a), Dallas, TX 75216, USA. Electronic address: subhash.banerjee@utsouthwestern.edu.
authors.forename: Subhash
authors.initials: S
authors.lastname: Banerjee
mesh_terms: D000800:Angioplasty, Balloon / Q000295:instrumentation*; D020099:Coated Materials, Biocompatible; D004867:Equipment Design; D006801:Humans; D058729:Peripheral Arterial Disease / Q000628:therapy*; D017410:Practice Guidelines as Topic
chemical_list: D020099:Coated Materials, Biocompatible
keywords: Drug-coated balloons; Endovascular intervention; Femoropopliteal peripheral artery; Infrapopliteal peripheral artery; Paclitaxel