title: Syndrome of Inappropriate Secretion of Antidiuretic Hormone Caused by Carboplatin After Switching from Cisplatin in a Metastatic Urethral Cancer Patient.
abstract: There is no established chemotherapy regimen in metastatic primary urethral cancer (mPUC). The efficacy of a cisplatin (CDDP)-based regimen has been reported, however, when the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) occurs, the chemotherapy regimen should be changed to another platinum compound. In this report, we describe a 66-year-old woman who was diagnosed as mPUC with, CDDP-induced SIADH. After switching her to CBDCA and careful managing her sodium balance, three courses of the chemotherapy regimen were completed.
authors.affiliation: Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Sugiyama
authors.affiliation: Department of Nephro-Urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Naiki
authors.affiliation: Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kondo
authors.affiliation: Department of Nephro-Urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
authors.forename: Keitaro
authors.initials: K
authors.lastname: Iida
authors.affiliation: Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kondo
authors.affiliation: Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan.
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Tasaki
authors.affiliation: Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Kataoka
authors.affiliation: Department of Endocrinology and Diabetes, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
authors.forename: Asami
authors.initials: A
authors.lastname: Hotta
authors.affiliation: Department of Nephro-Urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yasui
authors.affiliation: Department of Pharmacy, Nagoya City University Hospital, Nagoya, Japan; Department of Clinical Pharmaceutics, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Kimura
keywords: Carboplatin; Cisplatin; SIADH; Urethral carcinoma