title: Effects of Intravenous Pharmacopuncture with Harmonizing and Releasing Formulas on Hepatic Recovery after Partial Hepatectomy in Rats.
abstract: The objective of this study was to find out the effect of intravenous pharmacopuncture on hepatic recovery after partial hepatectomy in rats. Male Sprague-Dawley rats were randomly divided into five groups: normal group, control group, saline group, and two experimental groups. Except for those in the normal group, the rats underwent partial hepatectomy. Those in the control group did not receive any treatment. Those in the saline group received an intravenous injection with saline. Those in the two experimental groups received intravenous pharmacopuncture with SihoJigak-tang or DanchiSoyo-san extracts (10 mg/kg). Serum total bilirubin and liver regeneration rate were measured on Day 7 after partial hepatectomy. Intravenous pharmacopuncture with SihoJigak-tang significantly increased the liver regeneration rate, and intravenous pharmacopuncture with DanchiSoyo-san significantly decreased serum total billirubin after partial hepatectomy.
authors.affiliation: Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University, Daejeon, South Korea.
authors.forename: Hyun-Jin
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University, Daejeon, South Korea.
authors.forename: Chan
authors.initials: C
authors.lastname: Lee
authors.affiliation: Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University, Daejeon, South Korea. Electronic address: docwindy@dju.ac.kr.
authors.forename: Yun-Kyoung
authors.initials: YK
authors.lastname: Yim
mesh_terms: D015670:Acupuncture Therapy / Q000379:methods*; D061605:Administration, Intravenous; D000818:Animals; D006498:Hepatectomy / Q000379:methods*; D008099:Liver / Q000187:drug effects / Q000502:physiology / Q000601:surgery*; D008115:Liver Regeneration / Q000187:drug effects / Q000502:physiology; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D010936:Plant Extracts
keywords: DanchiSoyo-san; SihoJigak-tang; hepatic recovery; partial hepatectomy