title: The Use of a Sea Salt-based Spray for Diabetic Foot Ulcers: A Novel Concept.
abstract: Several patients present to wound healing specialists seeking a natural or alternative medical approach to their wounds. The purpose of this prospective, case-cohort study of 10 patients was to evaluate the use of Oceanzyme Wound Care Spray (Ocean Aid, Inc, Boynton Beach, FL) in improving healing in diabetic foot ulcers during a 12-week period. This product contains water purified by reverse osmosis, coral reef sea salt, lysozyme, and sodium benzoate. The primary endpoint was wound closure, and secondary endpoints were infection rate and wound area reduction. Overall, 2 patients healed, 2 withdrew, and the remaining 6 had an average of 73% reduction in wound area. While more study is needed, the use of this sea salt-based spray may provide a viable alternative for patients seeking a natural therapy for their wound care.
authors.affiliation: Sherman Oaks Hospital, Los Angeles, CA.
authors.forename: David A
authors.initials: DA
authors.lastname: Pougatsch
authors.affiliation: Indiana Foot & Ankle, Jasper, IN.
authors.forename: Andrew
authors.initials: A
authors.lastname: Rader
authors.affiliation: Sherman Oaks Hospital, Los Angeles, CA.
authors.forename: Lee C
authors.initials: LC
authors.lastname: Rogers
mesh_terms: D000328:Adult; D000368:Aged; D000529:Complementary Therapies / Q000191:economics / Q000379:methods*; D003362:Cost-Benefit Analysis; D017719:Diabetic Foot / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012623:Seawater / Q000737:chemistry*; D012964:Sodium / Q000302:isolation & purification / Q000494:pharmacology*; D016896:Treatment Outcome; D014481:United States; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D012964:Sodium