title: Comparative study of extralevator vs. conventional abdominoperineal excision in a single centre in the developing world.
abstract: Abdominoperineal excision (APE) is used to resect cancers in the distal rectum and anus where sphincterpreserving surgery is not possible. It is associated with increased local recurrence rates compared to anterior resection. The extralevator abdominoperineal excision (ELAPE) was developed to reduce local recurrence and was widely adopted without sound evidence.
  
  
  OBJECTIVE
  To compare the short-term (2 years) outcomes of patients managed with ELAPE to those with conventional APE in a single institution in a developing country.
  
  
  METHODS
  A prospective database on all patients treated with prone ELAPE from 2010 to 2014 was compared to patients treated with conventional APE. Patient demographics, tumour characteristics, intra-operative tumour perforation, involvement of the circumferential resection margin (CRM), surgical complications and mortality are reported.
  
  
  RESULTS
  Fifty-six patients were treated with APE of which 29 were male. Median age was 56. Thirty underwent conventional APE (16 male; 14 female) and 26 underwent ELAPE (15 male; 11 female). The groups were similar in age, tumour histology, height above anal verge clinical staging and response to neoadjuvant treatment. Perineal closure techniques in both cohorts were similar. There was no difference in intra-operative tumour perforation, involvement of the CRM, perineal wound complications or 30-day mortality in the 2 groups.
  
  
  CONCLUSIONS
  There is no difference in the important short-term outcomes of conventional APE when compared to ELAPE.
authors.affiliation: Student at the Amsterdam University, Amsterdam Medical Centre, Amsterdam, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Oostenbroek
authors.affiliation: Consultant Colorectal Surgeon, University of Cape Town, Groote Schuur Hospital, South Africa.
authors.forename: E
authors.initials: E
authors.lastname: Coetzee
authors.affiliation: Consultant Colorectal Surgeon, University of Cape Town, Groote Schuur Hospital, South Africa.
authors.forename: A
authors.initials: A
authors.lastname: Boutall
authors.affiliation: Associate Professor, Department of Colorectal Surgery, University of Cape Town, Groote Schuur Hospital, South Africa.
authors.forename: R
authors.initials: R
authors.lastname: Baigrie
authors.affiliation: Associate Professor, Department of Colorectal Surgery, University of Cape Town, Groote Schuur Hospital, South Africa.
authors.forename: P
authors.initials: P
authors.lastname: Goldberg