title: A rare breed: Wild-type braf and ighv expression in a 29 year old lady with classical hairy cell leukemia.
abstract: The V600 BRAF mutation has been described as a key mutation in the pathogenesis of classical hairy cell leukemia (c-HCL) cases without expression of a mutant immunoglobulin heavy chain (IgHV). Here we present a rare case of c-HCL with neither V600 BRAF mutation nor the aforementioned IgHV variant successfully treated with cladribine and review the current literature on its use in women of childbearing age/pregnancy.
authors.affiliation: Department of Internal Medicine, George Washington U niversity School of Medicine and Health Sciences, Washington, DC, United States of America.
authors.forename: Aneesha
authors.initials: A
authors.lastname: Hossain
authors.affiliation: Department of Internal Medicine, George Washington U niversity School of Medicine and Health Sciences, Washington, DC, United States of America.
authors.forename: Hind
authors.initials: H
authors.lastname: Rafei
authors.affiliation: Department of Pathology, George Washington University Medical Faculty Associates, Washington, DC, United States of America.
authors.forename: Amar
authors.initials: A
authors.lastname: Jariwala
authors.affiliation: Department of Hematology and Oncology, George Washington University Medical Faculty Associates, 2150 Pennsylvania Ave NW, Washington, DC 20037, United States of America.
authors.forename: Khaled
authors.initials: K
authors.lastname: El-Shami