title: Chemical composition, antioxidant and antibacterial activities of Tamarix balansae J. Gay aerial parts.
abstract: A previously undescribed phenolic sulphate ester, potassium 34-dihydroxy-3-methoxybenzoic acid methyl ester-5-sulphate (1), along with nine known flavonoids, kaempferol-3-O-potassium sulphate-4',7-dimethyl ether (2), kaempferol-4',7-dimethyl ether (3), rhamnocitrin-3-O-potassium sulphate (4), rhamnocitrin (5), kaempferol (6), quercetin (7), afzelin (8), quercetin-3-O-α-l-rhamnopyranoside (9) and luteolin-3'-O-potassium sulphate (10) were isolated from the aerial parts of Tamarix balansae. Structures elucidation was performed by comprehensive 1D and 2D NMR analyses, mass spectrometry and by comparison with literature data. The antibacterial assay against Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa bacteria showed a good activity for 2, 3, 7 and 9, with MICs ranging from 62.5 to 250 μg/mL. The abilities of these compounds to scavenge the DPPH were evaluated. Compounds 1, 7, 9 and 10 exhibited a good antiradical activity potential with IC50values ranging from 3.0 to 115.5 μg/mL, compared with ascorbic acid (IC507.4 μg/mL) which was used as positive control.
authors.affiliation: a Laboratoire d'Obtention des Substances Thérapeutiques (LOST), Département de chimie , Université des frères Mentouri-Constantine , Constantine , Algeria.
authors.forename: Abbes
authors.initials: A
authors.lastname: Benmerache
authors.affiliation: a Laboratoire d'Obtention des Substances Thérapeutiques (LOST), Département de chimie , Université des frères Mentouri-Constantine , Constantine , Algeria.
authors.forename: Mounira
authors.initials: M
authors.lastname: Benteldjoune
authors.affiliation: b ICMR-UMR CNRS 7312, Groupe Isolement et Structure , Reims , France.
authors.forename: Abdulmagid
authors.initials: A
authors.lastname: Alabdul Magid
authors.affiliation: b ICMR-UMR CNRS 7312, Groupe Isolement et Structure , Reims , France.|c Laboratoire de Microbiologie , UFR de Pharmacie , Reims , France.
authors.forename: Amin
authors.initials: A
authors.lastname: Abedini
authors.affiliation: a Laboratoire d'Obtention des Substances Thérapeutiques (LOST), Département de chimie , Université des frères Mentouri-Constantine , Constantine , Algeria.
authors.forename: Djemaa
authors.initials: D
authors.lastname: Berrehal
authors.affiliation: a Laboratoire d'Obtention des Substances Thérapeutiques (LOST), Département de chimie , Université des frères Mentouri-Constantine , Constantine , Algeria.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Kabouche
authors.affiliation: c Laboratoire de Microbiologie , UFR de Pharmacie , Reims , France.
authors.forename: Sophie C
authors.initials: SC
authors.lastname: Gangloff
authors.affiliation: b ICMR-UMR CNRS 7312, Groupe Isolement et Structure , Reims , France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Voutquenne-Nazabadioko
authors.affiliation: a Laboratoire d'Obtention des Substances Thérapeutiques (LOST), Département de chimie , Université des frères Mentouri-Constantine , Constantine , Algeria.
authors.forename: Zahia
authors.initials: Z
authors.lastname: Kabouche
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D032363:Tamaricaceae / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D005419:Flavonoids; D016166:Free Radical Scavengers; D010636:Phenols; D010936:Plant Extracts
keywords: Tamaricaceae; Tamarix balansae; antibacterial activity; antioxidant activity; flavonoids