title: CDC Grand Rounds: Public Health Strategies to Prevent Neonatal Abstinence Syndrome.
abstract: Neonatal abstinence syndrome (NAS) is a drug withdrawal syndrome that most commonly occurs in infants after in utero exposure to opioids, although other substances have also been associated with the syndrome (1). NAS usually appears within 48-72 hours of birth with a constellation of clinical signs, including central nervous system irritability (e.g., tremors), gastrointestinal dysfunction (e.g., feeding difficulties), and temperature instability (1) (Box 1). Opioid exposure during pregnancy might result from clinician-approved use of prescription opioids for pain relief; misuse or abuse of prescription opioids; illicit use (e.g., heroin); or medication-assisted treatment (MAT) of opioid use disorder (2) (Box 2).
authors.forename: Jean Y
authors.initials: JY
authors.lastname: Ko
authors.forename: Sara
authors.initials: S
authors.lastname: Wolicki
authors.forename: Wanda D
authors.initials: WD
authors.lastname: Barfield
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Patrick
authors.forename: Cheryl S
authors.initials: CS
authors.lastname: Broussard
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Yonkers
authors.forename: Rebecca
authors.initials: R
authors.lastname: Naimon
authors.forename: John
authors.initials: J
authors.lastname: Iskander
mesh_terms: D002487:Centers for Disease Control and Prevention, U.S.; D017281:Cost of Illness; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007231:Infant, Newborn; D007878:Legislation as Topic; D009357:Neonatal Abstinence Syndrome / Q000453:epidemiology / Q000517:prevention & control*; D009293:Opioid-Related Disorders / Q000453:epidemiology / Q000517:prevention & control; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D015980:Public Health Practice; D014481:United States / Q000453:epidemiology