title: Depression and resilience mediates the effect of family function on quality of life of the elderly.
abstract: BACKGROUND
  Family function, which improves individual resilience and strongly link to quality of life (QOL) among the elderly, increases the risk of depression. Because of these demonstrated relationships, it can be hypothesized that both depression and resilience are mediators of the association between family function and QOL.
  
  
  METHODS
  To test this hypothesis, the structural equation model (SEM) constructed by Amos 21.0 was employed to assess the indirect effect of depression (Geriatric Depression Scale, GDS) and resilience (Connor-Davidson Resilience Scale, CD-RISC) on the relationship between family function (Family APGAR Score, APGAR) and QOL (12-item Short Form health survey, SF-12) in 474 elderly adults from three communities in Guangzhou, China.
  
  
  RESULTS
  Correlation matrix showed that depression is significantly negatively correlated with family functioning (r=-0.54, P<0.01), resilience (r=-0.46, P<0.01) and QOL (r=-0.63, P<0.01), while resilience is significantly positively correlated with family functioning (r=0.35, P<0.01) and QOL (r=0.40, P<0.01). SEM indicated that Family functioning appeared to have significant indirect effects through resilience (β=0.089) and depression (β=0.307; combined β=0.056) on QOL (R2=0.55). The model fit indices showed a good fit of the model of the data (χ2/df=1.362, P>0.05, SRMR=0.023, RMSEA=0.028, GFI=0.985, NFI=0.987, TLI=0.993, CFI=0.996).
  
  
  CONCLUSIONS
  The finding supports the assumption that depression and resilience are consistent intermediary factors of the relationship between family function and QOL among the elderly.
authors.affiliation: School of Nursing, Guangzhou Medical University, China.
authors.forename: Canjie
authors.initials: C
authors.lastname: Lu
authors.affiliation: School of Nursing, Guangzhou Medical University, China.
authors.forename: Lexin
authors.initials: L
authors.lastname: Yuan
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou, China.
authors.forename: Weiquan
authors.initials: W
authors.lastname: Lin
authors.affiliation: School of Nursing, Guangzhou Medical University, China. Electronic address: zhouying0610@163.com.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: School of Nursing, Guangdong Food and Drug Vocational College, China.
authors.forename: Shengmao
authors.initials: S
authors.lastname: Pan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003863:Depression / Q000523:psychology*; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D055500:Resilience, Psychological
keywords: Family function; Geriatric depression; Mediator; Quality of life; Resilience