title: Donovanosis With Bowen Disease.
abstract: A 45-year-old farmer presented with ulcers and plaques over his scrotum for the past 4 to 5 years. The condition started as a small lesion on the shaft of the penis, which improved with treatment; however, after 2 to 3 months, papulonodular lesions developed on the scrotum, which increased in size and subsequently broke down to form ulcers. He denied drug abuse but had a history of multiple unprotected sexual exposures. He was prescribed oral antibiotics, which improved the lesions, but he failed to take the antibiotics for more than a week. He also used powders, lotions, and salves (exact nature not known), which did not help and sometimes even burned the skin. After stopping the medicine, he developed new lesions that followed a similar course. Examination revealed nontender ulcers on the scrotum with raised, rolled-out margins and pale red, granulation tissue that bled on touch (Figure 1). In addition, there were nodules with a pinkish red granular surface and scaly erythematous plaques on the scrotum. Regional lymph nodes were not enlarged.
authors.affiliation: Department of Dermatology, Venereology & Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India; narangtarun@yahoo.co.in.
authors.forename: Tarun
authors.initials: T
authors.lastname: Narang
authors.affiliation: Department of Microbiology, Gian Sagar Medical College and Hospital, Ram Nagar, Banur, Patiala, India.
authors.forename: Ashwini
authors.initials: A
authors.lastname: Manhas
authors.affiliation: Silver Oaks Multispecialty Hospital, Mohali, Punjab, India.
authors.forename: Bhushan
authors.initials: B
authors.lastname: Kumar
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001707:Biopsy, Needle; D001913:Bowen's Disease / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D003879:Dermatologic Agents / Q000627:therapeutic use; D000067565:Farmers; D005500:Follow-Up Studies; D006100:Granuloma Inguinale / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents