title: A case of symptomatic granular cell tumor of the sellar region with large calcification.
abstract: We report here a rare case of symptomatic granular cell tumor (GCT) of the sellar region with a large calcification. A 70-year-old woman presented with a sellar mass, accompanied by bitemporal hemianopia. The patient was diagnosed preoperatively as having a craniopharyngioma or a pituitary adenoma, because of the large calcification. The patient underwent surgical tumor resection via endoscopic trans-sphenoidal surgery and was diagnosed pathologically as having GCT. The patient's postoperative course was uneventful and her visual field disturbance improved soon after the operation. We briefly discuss the pathological discrimination of GCT and other sellar tumors, since there are many unclear points concerning this rare tumor.
authors.affiliation: Department of Neurological Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Shun
authors.identifier: http://orcid.org/0000-0003-0439-9277
authors.initials: S
authors.lastname: Yamamuro
authors.affiliation: Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Homma
authors.affiliation: Department of Neurological Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Yuya
authors.initials: Y
authors.lastname: Hanashima
authors.affiliation: Department of Neurological Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Sodai
authors.initials: S
authors.lastname: Yoshimura
authors.affiliation: Department of Neurological Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Oshima
authors.affiliation: Division of Morphological and Functional Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Sumie
authors.initials: S
authors.lastname: Ohni
authors.affiliation: Division of Oncologic Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kusumi
authors.affiliation: Department of Neurological Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Atsuo
authors.initials: A
authors.lastname: Yoshino
mesh_terms: D000368:Aged; D002114:Calcinosis / Q000473:pathology*; D005260:Female; D016586:Granular Cell Tumor / Q000473:pathology*; D006801:Humans; D010911:Pituitary Neoplasms / Q000473:pathology*
keywords: calcification; endoscopic transsphenoidal surgery; granular cell tumor of sellar region; pathological discrimination; symptomatic case