title: Hypopituitarism presenting as congestive heart failure.
abstract: Sheehan's syndrome (SS) develops as a result of ischemic pituitary necrosis due to severe postpartum hemorrhage and is characterized by various degrees of hypopituitarism. Although the occurrence of SS is now rare, it should still be considered in any woman with a history of peripartum hemorrhage who develops manifestations of pituitary hormone deficiency any time following the event. Appropriate hormone replacement therapy results in marked clinical improvement. We present an unusual case of SS in a young lady who continued to have normal menstruation after the index event, had two spontaneous pregnancies, and was diagnosed only 11 years later when she presented to us with acute heart failure.
authors.affiliation: Department of Medicine, University College of Medical Sciences, GTB Hospital, New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Giri
authors.affiliation: Department of Medicine, University College of Medical Sciences, GTB Hospital, New Delhi, India.
authors.forename: P
authors.initials: P
authors.lastname: Bansal
authors.affiliation: Department of Medicine, University College of Medical Sciences, GTB Hospital, New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Malik
authors.affiliation: Department of Medicine, University College of Medical Sciences, GTB Hospital, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Bansal
mesh_terms: D000309:Adrenal Insufficiency / Q000209:etiology*; D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging; D004562:Electrocardiography; D004652:Empty Sella Syndrome / Q000000981:diagnostic imaging*; D005260:Female; D030342:Genetic Diseases, Inborn / Q000209:etiology*; D005938:Glucocorticoids / Q000627:therapeutic use*; D006333:Heart Failure / Q000209:etiology*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D007037:Hypothyroidism; D007775:Lactation Disorders / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D011388:Prolactin / Q000172:deficiency*; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D005938:Glucocorticoids; D011388:Prolactin; D013974:Thyroxine