title: Evaluation of Gengigel® Application in the Management of Furcation with Coronally Advanced Flap through Surgical Re-Entry-A Split Mouth Clinical Study.
abstract: BACKGROUND
  One of the challenging and unique periodontal problem of Grade II furcation defect has been managed through different treatment modalities in the past. A successful approach is based on complete closure of the defect. Different regenerative approaches have been tried.
  
  
  OBJECTIVE
  This study was carried out with an aim to evaluate the role of Gengigel® (0.8% hyaluronic acid) as a potential material for regeneration of lost attachment apparatus.
  
  
  METHODS
  A total of 20 sites with Grade II furcation defects from 10 patients were selected using random sampling technique. These were divided into Group A (placement of hyaluronic acid) and Group B (without placement of hyaluronic acid) according to treatment modality. Furcation defect assessment was done in vertical and horizontal depth preoperatively and postoperatively at six months through surgical re-entry. Recorded data was subjected to the statistical analysis unpaired and paired t-tests for intergroup and intragroup comparisons respectively.
  
  
  RESULTS
  Mean plaque index, gingival index and bleeding index score showed statistically highly significant and significant results respectively, for both the groups at baseline and six months. Mean difference in probing pocket depth and Relative Attachment Level (RAL) were statistically highly significant, whereas, mean difference of gingival position margin was non significant for both the groups, at baseline and six months. Mean difference in horizontal component at baseline and six months was statistically highly significant for both the groups. Mean difference in vertical component at baseline and six months was statistically significant for both the groups. On comparison, the mean difference in vertical and horizontal component of Group A and Group B at six months was statistically not significant.
  
  
  CONCLUSIONS
  Both Gengigel® with coronally positioned flap and coronally positioned flap alone are effective in the treatment of Grade II furcation defects. The combination of Gengigel® with coronally positioned flap leads to better results in hard tissue measurement as compared to coronally positioned flap alone.
authors.affiliation: Private Practitioner, Goel Eye and Dental Clinic , Shimla, Himachal Pradesh, India .
authors.forename: Sugandha
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Head of Department, Department of Periodontology, Seema Dental College and Hospital , Rishikesh, Uttarakhand, India .
authors.forename: Suresh D
authors.initials: SD
authors.lastname: Kediege
authors.affiliation: Chief Periodontist, Ferris Mission Hospital , Firozpur, Punjab, India .
authors.forename: Akanksha
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Reader, Department of Oral Pathology and Microbiology, Maharaja Ganga Singh Dental College and Research Center , Shri Ganganagar, Rajasthan, India .
authors.forename: Kanu
authors.initials: K
authors.lastname: Jain
keywords: Hyaluronic acid; Periodontitis; Regeneration