title: Application of 70 kV Third-generation High-pitch Dual-source Coronary CT Angiography in Patients with Different Body Mass Index.
abstract: Objective 　To investigate the optimized range of body mass index (BMI) selection for patients undergoing 70 kV high-pitch dual-source coronary CT angiography (CCTA) on the third-generation dual-source CT (DSCT). Methods 　Patients undergoing prospective high-pitch ultra-low contrast media (CM) CCTA on the third-generation DSCT using the automatic tube voltage selection at 70 kV were included and divided into three groups:group A,with BMI≤24 kg/m2;group B,with 24 kg/m2<BMI<28 kg/m2;and group C,with BMI≥28 kg/m2. The baseline data,image quality results,and effective dose (ED) were evaluated and compared. Results 　No significant difference was found in age (H=2.36,P=0.78),heart rate (H=3.51,P=0.80),and ED(H=1.77,P=0.12) among three groups. The noise of the aortic root in group A was (21.66±4.00)HU,which was significantly lower than that in group C [(23.61±4.20)HU](F=2.05,P=0.03). The signal to noise ratio of aortic root in group A (18.61±5.28) was significantly better than that in group C (14.75±2.58) (F=5.31,P=0.02). No other significant difference in quantitative image quality were found among the three groups (all P >0.05). Subjective image quality in group A(Z=2.91,P=0.004) and B(Z=2.27,P=0.021) were both significantly better than that in group C. Conclusion 　The ultra-low tube voltage (70 kV) combined with ultra-low CM CCTA protocol on third-generation high-pitch DSCT may be better for patients with BMI<28 kg/m2 than those with BMI ≥28 kg/m2in China.
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yi
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Jian
authors.initials: J
authors.lastname: Cao
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Lu
authors.initials: L
authors.lastname: Lin
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Lingyan
authors.initials: L
authors.lastname: Kong
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Shu
authors.initials: S
authors.lastname: Jiang
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Peijun
authors.initials: P
authors.lastname: Liu
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Man
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Zhengyu
authors.initials: Z
authors.lastname: Jin
authors.affiliation: Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Yining
authors.initials: Y
authors.lastname: Wang
mesh_terms: D015992:Body Mass Index; D002681:China; D000072226:Computed Tomography Angiography / Q000379:methods*; D003287:Contrast Media; D006339:Heart Rate; D006801:Humans; D011446:Prospective Studies; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D059629:Signal-To-Noise Ratio
chemical_list: D003287:Contrast Media