title: A numerical and experimental study of acoustic micromixing in 3D microchannels for lab-on-a-chip devices.
abstract: This paper reports a numerical and experimental study of acoustic streaming and micromixing in polydimethylsiloxane microchannels. The mixing between two fluids flowing in microchannels was evaluated through the following conditions: (1) using a 28 μm thick β-poly(vinylidene fluoride) (β-PVDF) as a piezoelectric transducer actuated with a 24 Vpp and 40 MHz sinusoidal voltage; (2) using different flow rates. The results suggest that the mixing length increases as the flow rate increases and that the acoustic streaming phenomenon leads to a reduction on the mixing length. The good qualitative agreement between numerical and experimental results is a valuable indicator to predict the mixing performance of microfluidic devices, for improving biological fluid analysis in diagnosis lab-on-a-chip devices.
authors.forename: Susana O
authors.initials: SO
authors.lastname: Catarino
authors.forename: Vania C
authors.initials: VC
authors.lastname: Pinto
authors.forename: Paulo J
authors.initials: PJ
authors.lastname: Sousa
authors.forename: Rui
authors.initials: R
authors.lastname: Lima
authors.forename: Joao M
authors.initials: JM
authors.lastname: Miranda
authors.forename: Graca
authors.initials: G
authors.lastname: Minas
mesh_terms: D000162:Acoustics; D001826:Body Fluids / Q000737:chemistry; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D056656:Lab-On-A-Chip Devices; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods
chemical_list: D004129:Dimethylpolysiloxanes; C013830:baysilon