title: QAPD: an integrated system to quantify symptoms of Parkinson's disease.
abstract: The complex prevalence of Parkinson's disease (PD) symptoms has pushed research towards assessment tools that can assist in their quantification. There remains a need for a system capable of measuring symptoms during various tasks at multiple motor levels (kinematics and electromyography). In this paper, we present the development and initial validation of a quantitative assessment tool for Parkinson's disease (QAPD), a system designed to assist researchers and clinicians in the study of PD. The system integrates motion tracking, data gloves, and electromyography to collect movement related data from multiple body parts. As part of the system, a custom MATLAB® based toolbox has been designed to quantify bradykinesia, tremor, micrographia, and muscle rigidity using both standard and contemporary data analysis techniques. We believe this system can be a useful assessment tool to assist clinicians and researchers in diagnosing and estimating movement dysfunction in individuals with PD.
authors.forename: Vrajeshri
authors.initials: V
authors.lastname: Patel
authors.forename: Martin
authors.initials: M
authors.lastname: Burns
authors.forename: Michael
authors.initials: M
authors.lastname: Pourfar
authors.forename: Alon
authors.initials: A
authors.lastname: Mogilner
authors.forename: Douglas
authors.initials: D
authors.lastname: Kondziolka
authors.forename: Ramana
authors.initials: R
authors.lastname: Vinjamuri
mesh_terms: D006801:Humans; D018476:Hypokinesia / Q000175:diagnosis; D009068:Movement; D009127:Muscle Rigidity / Q000175:diagnosis; D010300:Parkinson Disease / Q000175:diagnosis* / Q000503:physiopathology; D063189:Symptom Assessment; D014202:Tremor / Q000175:diagnosis