title: Viewing oxidative stress through the lens of oxidative signalling rather than damage.
abstract: Concepts of the roles of reactive oxygen species (ROS) in plants and animals have shifted in recent years from focusing on oxidative damage effects to the current view of ROS as universal signalling metabolites. Rather than having two opposing activities, i.e. damage and signalling, the emerging concept is that all types of oxidative modification/damage are involved in signalling, not least in the induction of repair processes. Examining the multifaceted roles of ROS as crucial cellular signals, we highlight as an example the loss of photosystem II function called photoinhibition, where photoprotection has classically been conflated with oxidative damage.
authors.affiliation: Centre for Plant Sciences, School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K. c.foyer@leeds.ac.uk.
authors.forename: Christine H
authors.initials: CH
authors.lastname: Foyer
authors.affiliation: School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, U.K.
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Ruban
authors.affiliation: Institute of Plant Sciences Paris-Saclay IPS2, Univ Paris Sud, CNRS, INRA, Univ Evry, Univ Paris-Diderot, Sorbonne Paris-Cite, Universite Paris-Saclay, Rue de Noetzlin, Orsay 91405, France.
authors.forename: Graham
authors.initials: G
authors.lastname: Noctor
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D002734:Chlorophyll / Q000819:agonists / Q000378:metabolism; D002736:Chloroplasts / Q000378:metabolism / Q000528:radiation effects / Q000648:ultrastructure; D005453:Fluorescence; D008027:Light; D055537:Light Signal Transduction / Q000502:physiology*; D009249:NADP / Q000096:biosynthesis; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D010788:Photosynthesis / Q000502:physiology*; D045332:Photosystem II Protein Complex / Q000502:physiology*; D010944:Plants / Q000378:metabolism / Q000528:radiation effects* / Q000648:ultrastructure; D017382:Reactive Oxygen Species / Q000378:metabolism*
chemical_list: D045332:Photosystem II Protein Complex; D017382:Reactive Oxygen Species; D002734:Chlorophyll; D009249:NADP; D000255:Adenosine Triphosphate
keywords: cell signalling; oxidative stress; photoinhibition; photosynthesis; reactive oxygen species