title: Thin-film, high-density micro-electrocorticographic decoding of a human cortical gyrus.
abstract: High-density electrocorticography (ECoG) arrays are promising interfaces for high-resolution neural recording from the cortical surface. Commercial options for high-density arrays are limited, and historically tradeoffs must be made between spatial coverage and electrode density. However, thin-film technology is a promising alternative for generating electrode arrays capable of large area coverage and high channel count, with resolution on the order of cortical columns in the functional surface unit of a human gyrus. Here, we evaluate the sensing performance of a high-density thin-film 128-electrode array designed specifically for recording the distributed neural activity of a single human cortical gyrus. We found robust field potential responses throughout the superior temporal gyrus evoked by speech sounds, and clear phonetic feature selectivity at the resolution of 2 mm inter-electrode distance. Decoding accuracy improved with increasing density of electrodes over all three patients tested. Thin-film ECoG has significant potential for high-density neural interface applications at the scale of a human gyrus.
authors.forename: Leah
authors.initials: L
authors.lastname: Muller
authors.forename: Sarah
authors.initials: S
authors.lastname: Felix
authors.forename: Kedar G
authors.initials: KG
authors.lastname: Shah
authors.lastname: Kye Lee
authors.forename: Satinderpall
authors.initials: S
authors.lastname: Pannu
authors.forename: Edward F
authors.initials: EF
authors.lastname: Chang
mesh_terms: D002540:Cerebral Cortex; D000069280:Electrocorticography; D004567:Electrodes, Implanted; D004569:Electroencephalography; D006801:Humans