title: Bimane: A Visible Light Induced Fluorescent Photoremovable Protecting Group for the Single and Dual Release of Carboxylic and Amino Acids.
abstract: A series of ester conjugates of carboxylic and amino acids were synthesized based on bimane fluorescent photoremovable protecting group (FPRPG). The photorelease of single and dual (same as well as different) carboxylic and amino acids is demonstrated from a single bimane molecule on irradiation with visible light (λ ≥ 410 nm). The detailed mechanistic study of photorelease revealed that the release of two caged acids is simultaneous but in a stepwise pathway.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Kharagpur , Kharagpur, 721302 West Bengal, India.
authors.forename: Amrita
authors.initials: A
authors.lastname: Chaudhuri
authors.affiliation: Department of Chemistry, Indian Institute of Technology Kharagpur , Kharagpur, 721302 West Bengal, India.
authors.forename: Yarra
authors.initials: Y
authors.lastname: Venkatesh
authors.affiliation: Department of Chemistry, Indian Institute of Technology Kharagpur , Kharagpur, 721302 West Bengal, India.
authors.forename: Krishna Kalyani
authors.initials: KK
authors.lastname: Behara
authors.affiliation: Department of Chemistry, Indian Institute of Technology Kharagpur , Kharagpur, 721302 West Bengal, India.
authors.forename: N D Pradeep
authors.identifier: 0000-0001-6806-9774
authors.initials: ND
authors.lastname: Singh
mesh_terms: D000596:Amino Acids; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D002264:Carboxylic Acids; D008027:Light; D015394:Molecular Structure; D010782:Photolysis
chemical_list: D000596:Amino Acids; D019086:Bridged Bicyclo Compounds, Heterocyclic; D002264:Carboxylic Acids; C021149:bimanes