title: Diagnosis and Management of Type 2 Diabetic Kidney Disease.
abstract: Type 2 diabetic kidney disease (DKD) is the most common cause of CKD and ESRD worldwide, and carries with it enormous human and societal costs. The goal of this review is to provide an update on the diagnosis and management of DKD based on a comprehensive review of the medical literature. Topics addressed include the evolving presentation of DKD, clinical differentiation of DKD from non-DKD, a state-of-the-art evaluation of current treatment strategies, and promising emerging treatments. It is expected that the review will help clinicians to diagnose and manage patients with DKD.
authors.affiliation: Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Simit M
authors.initials: SM
authors.lastname: Doshi
authors.forename: Allon N
authors.initials: AN
authors.lastname: Friedman
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D050110:Bariatric Surgery; D001794:Blood Pressure / Q000187:drug effects; D031204:Caloric Restriction; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology; D003937:Diagnosis, Differential; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D007668:Kidney / Q000187:drug effects* / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D011237:Predictive Value of Tests; D012076:Renal Agents / Q000009:adverse effects / Q000627:therapeutic use*; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D007004:Hypoglycemic Agents; D012076:Renal Agents
keywords: Chronic; Costs and Cost Analysis; Diabetic Nephropathies; Disease Management Disease Management; Goals; Humans; Kidney Failure; Publications; Renal Insufficiency