title: Associations of obesity with newly diagnosed and previously known atopic diseases in Chinese adults: a case-control study.
abstract: To assess the associations of obesity with newly diagnosed and previously known atopic disorders in Chinese adults. 4,629 adults aged 18 years or older were recruited in Harbin, China. Among them, 1,114 were previously diagnosed atopic cases, 1,298 were newly diagnosed cases, and 2,217 non-atopic controls. Obesity and overweight are defined according to the criteria established by the Working Group on Obesity in China. The associations of obesity with known and newly diagnosed atopic disorders were assessed using logistic regressions. Obesity was significantly associated with known atopic disorders (adjusted OR = 2.41 (95% CI: 1.81, 3.22)). The association of obesity with newly diagnosed atopic cases was not as strong as that with known cases, and was not statistically significant (adjusted OR = 1.27 (95% CI: 0.94, 1.72)). The similar pattern was observed in different allergic diseases, gender and age stratifications. The association between overweight and atopic diseases were not significant. Obesity is strongly associated with previously diagnosed atopic cases but not so with newly diagnosed atopic cases in Chinese adults. It is likely that people with atopic disorders have a higher risk of developing obesity. Our findings are important for the management of atopic disorders and chronic disease prevention among atopic disease patients.
authors.affiliation: Department of Biostatistics, Public Health College, Harbin Medical University, Harbin City, Heilongjiang Province, China.
authors.forename: Biao
authors.initials: B
authors.lastname: Xie
authors.affiliation: School of Medicine, the University of Queensland, Room 817, Health Sciences Building, Royal Brisbane &Women's Hospital, Herston QLD, Australia.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Biostatistics, Public Health College, Harbin Medical University, Harbin City, Heilongjiang Province, China.
authors.forename: Yupeng
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Biostatistics, Public Health College, Harbin Medical University, Harbin City, Heilongjiang Province, China.
authors.forename: Meina
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of General Medicine, The Second Affiliated Hospital, Harbin Medical University, Harbin City, Heilongjiang Province, China.
authors.forename: Yongchen
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D044466:Asian People; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000453:epidemiology*; D016017:Odds Ratio; D011159:Population Surveillance; D015995:Prevalence; D012307:Risk Factors; D055815:Young Adult