title: Analytical Methods for Metformin Estimation.
abstract: Metformin is a widely prescribed oral anti-hyperglycemic agent used in the management of non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes. This article accentuates various analytical methods viz. HPLC, HPTLC, spectrophotometric, electrochemical, capillary electrophoresis and LC-MS for the estimation of metformin in pharmaceutical formulations and in biological matrices.
authors.affiliation: a Department of Chemistry , Banasthali Vidyapith , Banasthali , India.
authors.forename: Durgawati
authors.initials: D
authors.lastname: Patel
authors.affiliation: b KIET School of Pharmacy , KIET Group of Institutions , Ghaziabad , India.
authors.forename: Puspendra
authors.initials: P
authors.lastname: Kumar
authors.affiliation: c Department of Pharmacy , Banasthali University , Banasthali , India.
authors.forename: Swapnil
authors.identifier: http://orcid.org/0000-0003-2639-7096
authors.initials: S
authors.lastname: Sharma
authors.affiliation: a Department of Chemistry , Banasthali Vidyapith , Banasthali , India.
authors.forename: Jaya
authors.initials: J
authors.lastname: Dwivedi
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy; D055664:Electrochemical Techniques / Q000379:methods; D019075:Electrophoresis, Capillary / Q000379:methods; D006801:Humans; D007004:Hypoglycemic Agents / Q000032:analysis* / Q000493:pharmacokinetics; D013058:Mass Spectrometry / Q000379:methods; D008687:Metformin / Q000032:analysis* / Q000493:pharmacokinetics; D013053:Spectrophotometry / Q000379:methods
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin
keywords: Metformin; analytical methods; biological matrices; pharmaceutical formulations