title: Long-term predictive factors of the morphology based outcome in bare platinum coiled intracranial aneurysms: Evaluation by pre- and post-contrast 3D time-of-flight MR angiography.
abstract: OBJECTIVE
  Our aim was to identify long-term predictive factors of the morphology-based outcome (MBO) of bare platinum coiled intracranial aneurysms.
  
  
  METHODS
  A retrospective analysis of 96 bare platinum coiled intracranial aneurysms followed up from 1997 to 2016 using pre- and post-contrast 3D time-of-flight MR angiography (MRA) was performed. Logistic regression analysis was used to identify factors associated with a positive history of surrounding coil mass enhancement (SCME) and poor MBO. Spearman's rank correlation test was used to analyze the relationship between the initial angiographic result (IAR) class, sequential change of the SCME category, and MBO grade.
  
  
  RESULTS
  Factors independently associated with poor MBO were incomplete IAR (OR=14.94, 95%CI: 2.46, 289.21, P=0.002) and a history of SCME (OR=4.13, 95% CI: 1.05, 18.65, P=0.043). The MBO grade strongly correlated with the IAR class (correlation coefficient [r]=0.84, P<0.0001). MBO grade correlated with sequential change of the SCME category (r=0.56, P<0.0001). The sequential change of the SCME category correlated with IAR class (r=0.53, P<0.0001).
  
  
  CONCLUSIONS
  Although IAR and its class were strong long-term predictive factors of MBO, a history of SCME and upgrading of sequential change of SCME category were also long-term predictive factors of the MBO of bare platinum coiled intracranial aneurysms.
authors.affiliation: Department of Radiology, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan. Electronic address: fumiaki@xd6.so-net.ne.jp.
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Ueda
authors.affiliation: Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Uchiyama
authors.affiliation: Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Masanao
authors.initials: M
authors.lastname: Mohri
authors.affiliation: Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Kouichi
authors.initials: K
authors.lastname: Misaki
authors.affiliation: Department of Advanced Medical Imaging, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Matsui
authors.affiliation: Department of Neurosurgery, Fukui Prefectural Hospital, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Kida
authors.affiliation: Department of Radiology, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Junichiro
authors.initials: J
authors.lastname: Sanada
authors.affiliation: Department of Radiology, Fukui Prefectural Hospital, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Yoshikawa
authors.affiliation: Department of Radiology, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Aburano
authors.affiliation: Department of Radiology, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Yoshie
authors.affiliation: Department of Radiology, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Japan.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Gabata
mesh_terms: D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction; D003287:Contrast Media; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods*; D002532:Intracranial Aneurysm / Q000145:classification / Q000175:diagnosis / Q000628:therapy*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010984:Platinum; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; D010984:Platinum; D005682:Gadolinium
keywords: Contrast enhancement; Endovascular treatment; Intracranial aneurysm; Magnetic resonance angiography