title: Reversal of severe mitral regurgitation by device closure of a large patent ductus arteriosus in a premature infant.
abstract: We report a critically ill premature infant with severe mitral valve regurgitation associated with pulmonary hypertension and a severely dilated left atrium from a large patent ductus arteriosus. The mitral valve regurgitation improved significantly with normalisation of left atrial size 4 weeks after percutaneous closure of the patent ductus arteriosus. This case highlights the potential reversibility of severe mitral valve regurgitation with treatment of an underlying cardiac shunt.
authors.affiliation: Division of Pediatric Cardiology,Children's Hospital of Michigan,Carman and Ann Adams Department of Pediatrics,Wayne State University School of Medicine,Detroit,Michigan,United States of America.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Kheiwa
authors.affiliation: Division of Pediatric Cardiology,Children's Hospital of Michigan,Carman and Ann Adams Department of Pediatrics,Wayne State University School of Medicine,Detroit,Michigan,United States of America.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Ross
authors.affiliation: Division of Pediatric Cardiology,Children's Hospital of Michigan,Carman and Ann Adams Department of Pediatrics,Wayne State University School of Medicine,Detroit,Michigan,United States of America.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kobayashi
mesh_terms: D000792:Angiography; D006348:Cardiac Surgical Procedures / Q000379:methods*; D004374:Ductus Arteriosus, Patent / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*
keywords: Patent ductus arteriosus; mitral valve regurgitation; prematurity