title: Comparisons of the diagnostic accuracies of optical coherence tomography, micro-computed tomography, and histology in periodontal disease: anex vivostudy.
abstract: OBJECTIVE
  Optical coherence tomography (OCT) is a noninvasive diagnostic technique that may be useful for both qualitative and quantitative analyses of the periodontium. Micro-computed tomography (micro-CT) is another noninvasive imaging technique capable of providing submicron spatial resolution. The purpose of this study was to present periodontal images obtained usingex vivodental OCT and to compare OCT images with micro-CT images and histologic sections.
  
  
  METHODS
  Images ofex vivocanine periodontal structures were obtained using OCT. Biologic depth measurements made using OCT were compared to measurements made on histologic sections prepared from the same sites. Visual comparisons were made among OCT, micro-CT, and histologic sections to evaluate whether anatomical details were accurately revealed by OCT.
  
  
  RESULTS
  The periodontal tissue contour, gingival sulcus, and the presence of supragingival and subgingival calculus could be visualized using OCT. OCT was able to depict the surface topography of the dentogingival complex with higher resolution than micro-CT, but the imaging depth was typically limited to 1.2-1.5 mm. Biologic depth measurements made using OCT were a mean of 0.51 mm shallower than the histologic measurements.
  
  
  CONCLUSIONS
  Dental OCT as used in this study was able to generate high-resolution, cross-sectional images of the superficial portions of periodontal structures. Improvements in imaging depth and the development of an intraoral sensor are likely to make OCT a useful technique for periodontal applications.
authors.affiliation: Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea .
authors.forename: Jin-Young
authors.identifier: 0000-0002-6408-1618
authors.initials: JY
authors.lastname: Park
authors.affiliation: Intelligence R&D Laboratory, LG Electronics, Seoul, Korea .
authors.forename: Jung-Ho
authors.identifier: 0000-0003-4375-2213
authors.initials: JH
authors.lastname: Chung
authors.affiliation: Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea .
authors.forename: Jung-Seok
authors.identifier: 0000-0003-1276-5978
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Division of Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Center, Yonsei University College of Dentistry, Seoul, Korea .
authors.forename: Hee-Jin
authors.identifier: 0000-0002-1139-6261
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea .
authors.forename: Seong-Ho
authors.identifier: 0000-0001-6704-6124
authors.initials: SH
authors.lastname: Choi
authors.affiliation: Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea .
authors.forename: Ui-Won
authors.identifier: 0000-0001-6371-4172
authors.initials: UW
authors.lastname: Jung
keywords: Diagnosis; Histology; Optical coherence tomography; Periodontal diseases