title: Vitamin K Deficiency Presenting in an Infant with an Anterior Mediastinal Mass: A Case Report and Review of the Literature.
abstract: We report a case of a 1-month-old infant with spontaneous thymic hemorrhage secondary to severe vitamin K deficiency. He was brought to medical attention due to scrotal bruising and during evaluation was noted to be tachypneic and hypoxemic. Chest X-ray revealed an enlarged cardiothymic silhouette, and a follow-up echocardiogram revealed a mass in the anterior mediastinum. Routine laboratory work-up revealed severe coagulopathy. Further questioning revealed the patient had not received prophylactic vitamin K at birth. The coagulopathy resolved with administration of vitamin K, and a biopsy confirmed the anterior mediastinal mass was due to spontaneous thymic hemorrhage.
authors.affiliation: School of Medicine, University of Colorado, Boulder, CO, USA.
authors.forename: Mauricio A
authors.identifier: 0000-0002-7068-487X
authors.initials: MA
authors.lastname: Palau
authors.affiliation: School of Medicine, University of Colorado, Boulder, CO, USA.
authors.forename: Amanda
authors.initials: A
authors.lastname: Winters
authors.affiliation: School of Medicine, University of Colorado, Boulder, CO, USA.
authors.forename: Xiayuan
authors.initials: X
authors.lastname: Liang
authors.affiliation: School of Medicine, University of Colorado, Boulder, CO, USA.
authors.forename: Rachelle
authors.initials: R
authors.lastname: Nuss
authors.affiliation: School of Medicine, University of Colorado, Boulder, CO, USA.
authors.forename: Susan
authors.initials: S
authors.lastname: Niermeyer
authors.affiliation: School of Medicine, University of Colorado, Boulder, CO, USA.
authors.forename: Megan
authors.initials: M
authors.lastname: Gossling
authors.affiliation: School of Medicine, University of Colorado, Boulder, CO, USA.
authors.forename: Clyde
authors.initials: C
authors.lastname: Wright