title: A functional tool demonstrating the physical function decline independentof age in patients with predialysis chronic kidney disease.
abstract: Physical function decline in chronic kidney disease (CKD) patients has been a popular area of investigation in the last decade. It has been shown that lower levels of physical function in CKD results in poor outcomes. Nevertheless, nephrology practice does not include routine assessment of physical function. The aim of the present study is to elucidate which physical function assessment tool is better in CKD.
  
  
  
  A total of 148 predialysis CKD patients and 40 healthy controls were included in this cross-sectional single-blind study. CKD patients were further divided into two groups as stage 3 and stage 4/5. A hand dynamometer, the Short Physical Performance Battery (SPPB), and the Timed Up and Go Test (TUGT) were applied to all study participants.
  
  
  
  All physical function tests were significantly different between study and control groups. In multivariate analysis the SPPB (P < 0.001) emerged as an independent variable in CKD group.
  
  
  
  The SPPB is a promising, easily applicable, inexpensive, and sensitive tool that can indicate functional decline independent of age in predialysis CKD patients and can be used in clinical practice to monitor these patients.
authors.affiliation: Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Taşoğlu
authors.affiliation: Department of Nephrology, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Nergiz
authors.initials: N
authors.lastname: Bayrakci
authors.affiliation: Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey.
authors.forename: Didem
authors.initials: D
authors.lastname: Sezgin Özcan
authors.affiliation: Department of Nephrology, Faculty of Medicine, Hitit University, Çorum, Turkey.
authors.forename: Nihal
authors.initials: N
authors.lastname: Özkayar
authors.affiliation: Department of Cardiovascular Surgery, Ankara Yüksek İhtisas Training and Research Hospital, Ankara, Turkey.
authors.forename: İrfan
authors.initials: İ
authors.lastname: Taşoğlu
authors.affiliation: Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey.
authors.forename: Neşe
authors.initials: N
authors.lastname: Özgirgin
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D053581:Muscle Strength Dynamometer; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology* / Q000503:physiopathology*; D016037:Single-Blind Method; D055815:Young Adult