title: A case of collagenous colitis associated with novel oral anticoagulants use.
abstract: An 84-year-old man was referred to our hospital because of watery diarrhea. Due to cerebral infarction, he had started treatment with a novel oral anticoagulants (NOAC) 1 month prior to admission. The patient underwent blood tests, enhanced computed tomography, and colonoscopy, which indicated infectious or medicinal colitis. The diarrhea persisted and he developed hypokalemia, so a second colonoscopy was performed, which showed edematous mucosa. Colonic mucosal biopsies showed a thick collagen band in the subepithelial region, and collagenous colitis was diagnosed. The watery diarrhea subsequently resolved 1 week after changing the NOAC to warfarin. Reports on collagenous colitis caused by NOAC are very rare, and we consider this case valuable.
authors.affiliation: Department of Gastroenterology, Onomichi General Hospital.
authors.forename: Juri
authors.initials: J
authors.lastname: Ikemoto
authors.forename: Kouichi
authors.initials: K
authors.lastname: Nakadoi
authors.forename: Seiji
authors.initials: S
authors.lastname: Onogawa
authors.forename: Motomitsu
authors.initials: M
authors.lastname: Fukuhara
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Shishido
authors.forename: Keiji
authors.initials: K
authors.lastname: Hanada
authors.forename: Shuji
authors.initials: S
authors.lastname: Yonehara
mesh_terms: D000284:Administration, Oral; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D046729:Colitis, Collagenous / Q000139:chemically induced* / Q000175:diagnosis; D003113:Colonoscopy; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants