title: A case with atrophic autoimmune thyroiditis-related hypothyroidism causing multisystem involvement in early childhood.
abstract: The most common reason of acquired hypothyroidism is autoimmune (Hashimoto) thyroiditis. Autoimmune thyroiditis can be atrophic or goitrogenic. Atrophic autoimmune thyroiditis (ATT) related acquired hypothyroidism causes interruption of growth, obesity, and bone age retardation in early ages while goitrogenic thyroiditis has a higher incidence rate and mostly presents with diffuse goiter. We discuss the effects of hypothyroidism on various systems through a case found to have pericardial effusion during the echocardiography performed after cardiac murmur was detected and later diagnosed with ATT related hypothyroidism.
authors.affiliation: Clinics Of Pediatric Endocrinology, Dr. Sami Ulus Obstetrics and Gynecology and Pediatrics Training and Research Hospital, Ankara, Turkey.
authors.forename: Erdal
authors.initials: E
authors.lastname: Kurnaz
authors.affiliation: Clinics Of Pediatric Endocrinology, Dr. Sami Ulus Obstetrics and Gynecology and Pediatrics Training and Research Hospital, Ankara, Turkey.
authors.forename: Şenay
authors.initials: Ş
authors.lastname: Savaş-Erdeve
authors.affiliation: Clinics Of Pediatric Endocrinology, Dr. Sami Ulus Obstetrics and Gynecology and Pediatrics Training and Research Hospital, Ankara, Turkey.
authors.forename: Melikşah
authors.initials: M
authors.lastname: Keskin
authors.affiliation: Clinics Of Pediatric Cardiology Clinic, Dr. Sami Ulus Obstetrics and Gynecology and Pediatrics Training and Research Hospital, Ankara, Turkey.
authors.forename: Vehbi
authors.initials: V
authors.lastname: Doğan
authors.affiliation: Clinics Of Pediatric Endocrinology, Dr. Sami Ulus Obstetrics and Gynecology and Pediatrics Training and Research Hospital, Ankara, Turkey.
authors.forename: Semra
authors.initials: S
authors.lastname: Çetinkaya
authors.affiliation: Clinics Of Pediatric Endocrinology, Dr. Sami Ulus Obstetrics and Gynecology and Pediatrics Training and Research Hospital, Ankara, Turkey.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Aycan
mesh_terms: D002675:Child, Preschool; D003409:Congenital Hypothyroidism / Q000150:complications* / Q000175:diagnosis; D004452:Echocardiography; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006984:Hypertrophy / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D018482:Muscle, Skeletal / Q000187:drug effects / Q000473:pathology*; D009135:Muscular Diseases / Q000150:complications* / Q000175:diagnosis; D010490:Pericardial Effusion / Q000150:complications; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000188:drug therapy; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D013974:Thyroxine
keywords: Kocher-Debre-Semelaigne syndrome; atrophic autoimmune thyroiditis; pituitary expansion; rickets