title: Progressing MoodSwings. The upgrade and evaluation of MoodSwings 2.0: An online intervention for bipolar disorder.
abstract: MoodSwings 2.0 is a self-guided online intervention for bipolar disorder. The intervention incorporates technological improvements on an earlier validated version of the intervention (MoodSwings 1.0). The previous MoodSwings trial provides this study with a unique opportunity to progress previous work, whilst being able to take into consideration lesson learnt, and technological enhancements. The structure and technology of MoodSwings 2.0 are described and the relevance to other online health interventions is highlighted. An international team from Australia and the US updated and improved the programs content pursuant to changes in DSM-5, added multimedia components and included larger numbers of participants in the group discussion boards. Greater methodological rigour in this trial includes an attention control condition, quarterly telephone assessments, and red flag alerts for significant clinical change. This paper outlines these improvements, including additional security and safety measures. A 3 arm RCT is currently evaluating the enhanced program to assess the efficacy of MS 2.0; the primary outcome is change in depressive and manic symptoms. To our knowledge this is the first randomized controlled online bipolar study with a discussion board attention control and meets the key methodological criteria for online interventions.
authors.affiliation: Department of Psychiatry, University of Melbourne, Parkville, Australia; Federation University Australia, Ballarat, Australia. Electronic address: s.lauder@federation.edu.au.
authors.forename: S
authors.initials: S
authors.lastname: Lauder
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States; Bipolar and Depression Research Program, VA Palo Alto Health Care System, United States.
authors.forename: V E
authors.initials: VE
authors.lastname: Cosgrove
authors.affiliation: Department of Psychiatry, University of Melbourne, Parkville, Australia; Deakin University, IMPACT Strategic Research Centre, School of Medicine, Barwon Health, Geelong, Australia.
authors.forename: E
authors.initials: E
authors.lastname: Gliddon
authors.affiliation: Bipolar and Depression Research Program, VA Palo Alto Health Care System, United States.
authors.forename: D
authors.initials: D
authors.lastname: Grimm
authors.affiliation: Department of Psychiatry, University of Melbourne, Parkville, Australia; Deakin University, IMPACT Strategic Research Centre, School of Medicine, Barwon Health, Geelong, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Dodd
authors.affiliation: Department of Psychiatry, University of Melbourne, Parkville, Australia; Deakin University, IMPACT Strategic Research Centre, School of Medicine, Barwon Health, Geelong, Australia; School of Psychology, Deakin University, Burwood, Australia.
authors.forename: L
authors.initials: L
authors.lastname: Berk
authors.affiliation: Department of Psychiatry, University of Melbourne, Parkville, Australia.
authors.forename: D
authors.initials: D
authors.lastname: Castle
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, United States; Bipolar and Depression Research Program, VA Palo Alto Health Care System, United States.
authors.forename: T S
authors.initials: TS
authors.lastname: Suppes
authors.affiliation: Department of Psychiatry, University of Melbourne, Parkville, Australia; Deakin University, IMPACT Strategic Research Centre, School of Medicine, Barwon Health, Geelong, Australia; Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Australia; Orygen Youth Health Research Centre, Centre for Youth Mental Health, Melbourne, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Berk
mesh_terms: D000328:Adult; D000339:Affect / Q000502:physiology*; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001315:Australia; D001714:Bipolar Disorder / Q000628:therapy*; D016494:Computer Security / Q000592:standards; D005260:Female; D006801:Humans; D020407:Internet; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D009042:Motivation; D061214:Patient Safety; D011788:Quality of Life; D012107:Research Design; D012648:Self Care / Q000379:methods*; D057545:Social Stigma; D012944:Social Support; D012959:Socioeconomic Factors; D013813:Therapy, Computer-Assisted / Q000379:methods* / Q000592:standards; D014481:United States; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents