title: The Interaction Effects of Meteorological Factors and Air Pollution on the Development of Acute Coronary Syndrome.
abstract: This study investigated the interaction effects of meteorological factors and air pollutants on the onset of acute coronary syndrome (ACS). Data of ACS patients were obtained from the Taiwan ACS Full Spectrum Registry and comprised 3164 patients with a definite onset date during the period October 2008 and January 2010 at 39 hospitals. Meteorological conditions and air pollutant concentrations at the 39 locations during the 488-day period were obtained. Time-lag Poisson and logistic regression were used to explore their association with ACS incidence. One-day lag atmospheric pressure (AP), humidity, particulate matter (PM2.5, and PM10), and carbon monoxide (CO) all had significant interaction effects with temperature on ACS occurrence. Days on which high temperatures (>26 °C) and low AP (<1009 hPa) occurred the previous day were associated with a greater likelihood of increased incidence of developing ACS. Typhoon Morakot was an example of high temperature with extremely low AP associated with higher ACS incidence than the daily average. Combinations of high concentrations of PM or CO with low temperatures (<21 °C) and high humidity levels with low temperatures were also associated with increased incidence of ACS. Atmospheric pollution and weather factors have synergistic effects on the incidence of ACS.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.|Institute of Statistics and Information Science, National Changhua University of Education, Changhua, Taiwan.|School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.|Department of Beauty Science and Graduate Institute of Beauty Science Technology, Chienkuo Technology University, Changhua, Taiwan.
authors.forename: Ching-Hui
authors.initials: CH
authors.lastname: Huang
authors.affiliation: Institute of Statistics and Information Science, National Changhua University of Education, Changhua, Taiwan.
authors.forename: Heng-Cheng
authors.initials: HC
authors.lastname: Lin
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
authors.forename: Chen-Dao
authors.initials: CD
authors.lastname: Tsai
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
authors.forename: Hung-Kai
authors.initials: HK
authors.lastname: Huang
authors.affiliation: Institute of Statistics and Information Science, National Changhua University of Education, Changhua, Taiwan.
authors.forename: Ie-Bin
authors.initials: IB
authors.lastname: Lian
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.|School of Medicine, Chung Shan Medical University, Taichung, Taiwan.|Medical Research Center, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
authors.forename: Chia-Chu
authors.initials: CC
authors.lastname: Chang
mesh_terms: D054058:Acute Coronary Syndrome / Q000453:epidemiology / Q000209:etiology*; D000368:Aged; D000397:Air Pollution / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008685:Meteorological Concepts; D008875:Middle Aged; D012372:ROC Curve; D013624:Taiwan / Q000453:epidemiology