title: Micronutrient Status in 153 Patients with Anorexia Nervosa.
abstract: Micronutrient status in Anorexia Nervosa (AN) has been poorly documented and previous data are often contradictory. We aimed to assess micronutrient status in a large population of AN patients. The relationships between micronutrient status and body composition were also determined. Anthropometric, biochemical parameters and body composition data were collected at referral in 153 patients with AN (28.5 ± 11 years). At least one trace element deficit was observed in almost half of patients; the most frequent was selenium deficit (40% of patients). At least one vitamin deficit was observed in 45.7% of patients, mostly vitamin A and B9. Albumin, transthyretin and CRP were within normal range in most patients. No correlations were found between body composition and micronutrient status. Our study suggests that micronutrient status is often altered in AN patients, which may contribute to neuropsychiatric dysfunction. Monitoring of micronutrients and correction of deficits should be included in the routine care of AN patients.
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. najate.achamrah@chu-rouen.fr.|INSERM Unit 1073, 76183 Rouen, France. najate.achamrah@chu-rouen.fr.|Institute for Research and Innovation in Biomedicine, Normandie Université, 76183 Rouen, France. najate.achamrah@chu-rouen.fr.|Clinical Investigation Centre CIC 1404 INSERM, 76183 Rouen, France. najate.achamrah@chu-rouen.fr.
authors.forename: Najate
authors.initials: N
authors.lastname: Achamrah
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. moise.coffier@chu-rouen.fr.|INSERM Unit 1073, 76183 Rouen, France. moise.coffier@chu-rouen.fr.|Institute for Research and Innovation in Biomedicine, Normandie Université, 76183 Rouen, France. moise.coffier@chu-rouen.fr.
authors.forename: Moïse
authors.initials: M
authors.lastname: Coëffier
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. agnes.ribert@chu-rouen.fr.|INSERM Unit 1073, 76183 Rouen, France. agnes.ribert@chu-rouen.fr.|Institute for Research and Innovation in Biomedicine, Normandie Université, 76183 Rouen, France. agnes.ribert@chu-rouen.fr.
authors.forename: Agnès
authors.initials: A
authors.lastname: Rimbert
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. jocelyne.charle@chu-rouen.fr.
authors.forename: Jocelyne
authors.initials: J
authors.lastname: Charles
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. vanessa.folope@chu-rouen.fr.|INSERM Unit 1073, 76183 Rouen, France. vanessa.folope@chu-rouen.fr.|Institute for Research and Innovation in Biomedicine, Normandie Université, 76183 Rouen, France. vanessa.folope@chu-rouen.fr.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Folope
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. andre.petit@chu-rouen.fr.|INSERM Unit 1073, 76183 Rouen, France. andre.petit@chu-rouen.fr.|Institute for Research and Innovation in Biomedicine, Normandie Université, 76183 Rouen, France. andre.petit@chu-rouen.fr.
authors.forename: André
authors.initials: A
authors.lastname: Petit
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. pierre.dechlotte@chu-rouen.fr.|INSERM Unit 1073, 76183 Rouen, France. pierre.dechlotte@chu-rouen.fr.|Institute for Research and Innovation in Biomedicine, Normandie Université, 76183 Rouen, France. pierre.dechlotte@chu-rouen.fr.
authors.forename: Pierre
authors.initials: P
authors.lastname: Déchelotte
authors.affiliation: Nutrition Department, Rouen University Hospital, 76183 Rouen, France. sebastien.grigioni@chu-rouen.fr.|INSERM Unit 1073, 76183 Rouen, France. sebastien.grigioni@chu-rouen.fr.|Institute for Research and Innovation in Biomedicine, Normandie Université, 76183 Rouen, France. sebastien.grigioni@chu-rouen.fr.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Grigioni
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000097:blood*; D000886:Anthropometry; D001823:Body Composition; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002097:C-Reactive Protein / Q000378:metabolism; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D018977:Micronutrients / Q000097:blood* / Q000172:deficiency; D009752:Nutritional Status; D011228:Prealbumin / Q000378:metabolism; D012189:Retrospective Studies; D012709:Serum Albumin / Q000378:metabolism; D055815:Young Adult
chemical_list: D018977:Micronutrients; D011228:Prealbumin; D012709:Serum Albumin; D002097:C-Reactive Protein
keywords: anorexia nervosa; micronutrients