title: Chitosan/zinc oxide-polyvinylpyrrolidone (CS/ZnO-PVP) nanocomposite for better thermal and antibacterial activity.
abstract: A new biopolymer based ZnO-PVP nanocomposite was successfully synthesized by single step in situ precipitation method using chitosan as biosurfactant, zinc chloride as a source material, PVP as stabilizing agent and sodium hydroxide as precipitating agent. The chemical bonding and crystalline behaviors of chitosan, zinc oxide and PVP were confirmed by FT-IR and XRD analysis. The biopolymer connected ZnO particles intercalated PVP matrix was layer and rod like structure appeared in nanometer range confirmed by HR-SEM and TEM analysis. The surface topography image of CS/ZnO-PVP nanocomposite was obtained in the average thickness of 12nm was confirmed by AFM analysis. Thermal stability of cationic biopolymer based ZnO intercalated PVP has higher stability than CS-PVP and chitosan. Consequently, antimicrobial activity of chitosan/ZnO-PVP matrix acts as a better microbial inhibition activity than PVP-ZnO nanocomposite. The obtained above results demonstrate that CS and ZnO intercalated PVP matrix has better reinforced effect than other components. Therefore, Chitosan/ZnO-PVP nanocomposite may be a promising material for the biomedical applications.
authors.affiliation: Bio-nanomaterials Research Lab, Department of Industrial Chemistry, School of Chemical Sciences, Alagappa University, Karaikudi, 630003, Tamil Nadu, India.
authors.forename: M
authors.initials: M
authors.lastname: Karpuraranjith
authors.affiliation: Bio-nanomaterials Research Lab, Department of Industrial Chemistry, School of Chemical Sciences, Alagappa University, Karaikudi, 630003, Tamil Nadu, India. Electronic address: sthambi01@yahoo.co.in.
authors.forename: S
authors.initials: S
authors.lastname: Thambidurai
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001704:Biopolymers; D048271:Chitosan / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D018625:Microscopy, Atomic Force; D015394:Molecular Structure; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D011205:Povidone / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013816:Thermodynamics; D013818:Thermogravimetry; D014961:X-Ray Diffraction; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D001704:Biopolymers; D048271:Chitosan; D011205:Povidone; D015034:Zinc Oxide
keywords: Antibacterial activity; Chitosan; Nanocomposite; PVP; Thermal stability; ZnO