title: Massive perineal defect after radio-chemotherapy.
abstract: Herein, we present a rare complication of radio-chemotherapy. A young man presented with loss of urine from the posterior perineum that showed a massive disappearance. He underwent Hartmann procedure for rectal neoplasia, afterwards treated with intensity-modulated radiotherapy (IMRT) (until 67 Gy) and chemotherapy with FOLFOX protocol (Leucoverin calcium, Fluorouracil, Oxaliplatin).
authors.affiliation: Unit of Gastroenterology and Digestive Endoscopy Sandro Pertini Hospital Rome Italy.
authors.forename: Maddalena
authors.identifier: 0000-0001-5876-3199
authors.initials: M
authors.lastname: Zippi
authors.affiliation: Unit of Oncology Sandro Pertini Hospital Rome Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Ramponi
authors.affiliation: Unit of Oncology Sandro Pertini Hospital Rome Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Narduzzi
authors.affiliation: Unit of Oncology Sandro Pertini Hospital Rome Italy.
authors.forename: Antonio Maria
authors.initials: AM
authors.lastname: Alberti
keywords: Intensity‐modulated radiotherapy; posterior perineum; radio‐chemotherapy; surgery