title: New naphthalene derivative from the leaves of Cassia grandis L.
abstract: Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2), afzelin (3), quercitrin (4), epicatechin (5), (-)-epiafzelechin (6), isoquercitrin (7) and aloe emodin (8) were isolated from the ethyl acetate and methanol extracts. Their structures were elucidated by spectral evidences (UV, IR, MS,1H,13C, DEPT, HSQC and HMBC NMR), as well as by comparing with published data.
authors.affiliation: a Faculty of Natural Sciences, Department of Biochemistry , Tiengiang University , Chau Thanh , Vietnam.
authors.forename: Pham Thi Nhat
authors.initials: PTN
authors.lastname: Trinh
authors.affiliation: c School of education , Can Tho University , Can Tho , Vietnam.
authors.forename: Ngoc Quoc
authors.initials: NQ
authors.lastname: Luan
authors.affiliation: b Department of Bioactive Compound , Institute of Chemical Technology, Vietnam Academy of Science and Technology , Ho Chi Minh City , Vietnam.
authors.forename: Mai Dinh
authors.initials: MD
authors.lastname: Tri
authors.affiliation: c School of education , Can Tho University , Can Tho , Vietnam.
authors.forename: Vu Duy
authors.initials: VD
authors.lastname: Khanh
authors.affiliation: d Department of Pharmaceutical Biochemistry, Institute of Applied Materials Science , Vietnam Academy of Science and Technology , Ho Chi Minh City , Vietnam.
authors.forename: Nguyen Huu
authors.initials: NH
authors.lastname: An
authors.affiliation: b Department of Bioactive Compound , Institute of Chemical Technology, Vietnam Academy of Science and Technology , Ho Chi Minh City , Vietnam.
authors.forename: Phan Nhat
authors.initials: PN
authors.lastname: Minh
authors.affiliation: d Department of Pharmaceutical Biochemistry, Institute of Applied Materials Science , Vietnam Academy of Science and Technology , Ho Chi Minh City , Vietnam.
authors.forename: Pham Ngoc
authors.initials: PN
authors.lastname: An
authors.affiliation: e Faculty of Biotechnology, Department of Food Technology , Open University Ho Chi Minh City , Ho Chi Minh , Vietnam.
authors.forename: Nguyen Thi Le
authors.initials: NTL
authors.lastname: Thuy
authors.affiliation: f Faculty of Chemistry, Department of Organic Chemistry , Ho Chi Minh University of Science , Ho Chi Minh , Vietnam.
authors.forename: Nguyen Kim Phi
authors.initials: NKP
authors.lastname: Phung
authors.affiliation: d Department of Pharmaceutical Biochemistry, Institute of Applied Materials Science , Vietnam Academy of Science and Technology , Ho Chi Minh City , Vietnam.
authors.forename: Le Tien
authors.initials: LT
authors.lastname: Dung
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification; D002366:Cassia / Q000737:chemistry* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008362:Mannosides / Q000737:chemistry / Q000302:isolation & purification; D000432:Methanol / Q000737:chemistry; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D044945:Proanthocyanidins / Q000737:chemistry / Q000302:isolation & purification; D011794:Quercetin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D012431:Rutin / Q000032:analysis; D064210:Secondary Metabolism
chemical_list: D000880:Anthraquinones; D008362:Mannosides; D009281:Naphthalenes; D010936:Plant Extracts; D044945:Proanthocyanidins; C000624635:cassgranon D; C016527:isoquercitrin; C012526:quercitrin; D012431:Rutin; C477954:afzelin; D011794:Quercetin; C518327:aloe emodin; D000432:Methanol
keywords: Cassgranon D; Cassia grandis; naphthalene derivative