title: Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines.
abstract: Cyclopeptides have been recently used successfully as carriers for the multivalent presentation of carbohydrate and peptide antigens in immunotherapy. Beside their synthetic versatility, these scaffolds are indeed interesting due to their stability against enzyme degradation and low immunogenicity. This mini-review highlights the recent advances in the utilization of cyclopeptides to prepare fully synthetic vaccines prototypes against cancers and pathogens.
authors.affiliation: Univ. Grenoble Alpes, CNRS, DCM UMR 5250, F-38000 Grenoble, France. olivier.renaudet@univ-grenoble-alpes.fr.
authors.forename: Carlo
authors.initials: C
authors.lastname: Pifferi
authors.affiliation: Univ. Grenoble Alpes, CNRS, DCM UMR 5250, F-38000 Grenoble, France. olivier.renaudet@univ-grenoble-alpes.fr.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Berthet
authors.affiliation: Univ. Grenoble Alpes, CNRS, DCM UMR 5250, F-38000 Grenoble, France. olivier.renaudet@univ-grenoble-alpes.fr and Institut Universitaire de France, 103 boulevard Saint-Michel, 75005 Paris, France.
authors.forename: Olivier
authors.identifier: http://orcid.org/0000-0003-4963-3848
authors.initials: O
authors.lastname: Renaudet
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D019496:Cancer Vaccines / Q000737:chemistry; D002241:Carbohydrates / Q000737:chemistry*; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control; D010456:Peptides, Cyclic / Q000737:chemistry*; D014614:Vaccines, Synthetic / Q000737:chemistry*; D014765:Viral Vaccines / Q000737:chemistry; D014777:Virus Diseases / Q000517:prevention & control
chemical_list: D019496:Cancer Vaccines; D002241:Carbohydrates; D010456:Peptides, Cyclic; D014614:Vaccines, Synthetic; D014765:Viral Vaccines