title: Chiral N,N'-dioxide-Sc(NTf2)3complex-catalyzed asymmetric bromoamination of chalones with N-bromosuccinimide as both bromine and amide source.
abstract: The catalytic asymmetric bromoamination of chalcones with N-bromosuccinimide as both bromine and amide source was realized by using a chiral N,N'-dioxide-Sc(NTf2)3complex as an efficient catalyst. The corresponding chiral bromoamination products were obtained in high yields with high dr and good ee values (up to 92% yield, 93 : 7 dr and 97% ee) under mild reaction conditions.
authors.affiliation: Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China. lililin@scu.edu.cn xmfeng@scu.edu.cn.
authors.forename: Zhengmeng
authors.initials: Z
authors.lastname: Wang
authors.forename: Lili
authors.initials: L
authors.lastname: Lin
authors.forename: Pengfei
authors.initials: P
authors.lastname: Zhou
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Liu
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Feng