title: Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro[isobenzofuran-1,3'-isochroman] scaffolds.
abstract: A highly regioselective synthesis of functionalized 3H-spiro[isobenzofuran-1,3'-isochroman] scaffolds using a novel palladium-catalyzed tandem cyclization reaction is explored. During the reaction process, C-O, C-C and C-O bonds are sequentially formed in one pot via decarboxylative allenylpalladium formation, nucleophilic attack, arylpalladium addition and intramolecular nucleophilic attack.
authors.affiliation: Institute of Modern Physics, Chinese Academy of Sciences, 509 Nanchang Rd, Lanzhou, Gansu 730000, P. R. China. xinzhj@impcas.ac.cn liangjp100@impcas.ac.cn.
authors.forename: Liang
authors.initials: L
authors.lastname: Wang
authors.forename: Xuehu
authors.initials: X
authors.lastname: Li
authors.forename: Hua
authors.initials: H
authors.lastname: Tao
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
authors.forename: Xihong
authors.initials: X
authors.lastname: Lu
authors.forename: Wenyue
authors.initials: W
authors.lastname: Du
authors.forename: Tingting
authors.initials: T
authors.lastname: Jiang
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Xin
authors.forename: Jianping
authors.initials: J
authors.lastname: Liang