title: Classification of Human Milks Based on Their Trans 18:1 Fatty Acid Profile and Effect of Maternal Diet.
abstract: The diet of breastfeeding women influences the trans fatty acid (TFA) composition of the milk excreted. However, the effects associated to TFA are isomer-dependent and diverse TFA profiles may have different nutritional implications.
  
  
  
  The aim of this research was to evaluate whether certain TFA patterns in human milk fat can be used as indicators of TFA intake from different sources.
  
  
  
  Milk fat from 60 women were examined and classified based on their TFA profile and conjugated linoleic acid (CLA) contents by principal component analysis (PCA).
  
  
  
  The PCA of the data allowed the classification of the women into 3 groups depending on milk TFA content and profile. From the 60 subjects, 19 presented a TFA profile characteristic of ruminant products intake, 10 a typical TFA profile of industrial trans fats consumption and 31 a negligible trans content. Superimposed on this, 21 women presented high amounts of docosahexaenoic acid (22:6 n-3) which was related to fish intake.
  
  
  
  The present research overcome problems associated to heterogeneous groups in nutritional experiments by a statistical classification of lactating subjects based on the TFA composition of their milk. This classification could be extrapolated to other nutritional studies dealing with TFA analysis and samples of different nature as biological samples or foodstuffs.
authors.affiliation: 1 Food Research Centre , Agriculture and Agri-Food Canada, Guelph, Canada .
authors.forename: Pilar
authors.initials: P
authors.lastname: Gómez-Cortés
authors.affiliation: 2 Departamento de Bioactividad y Análisis de Alimentos, Instituto de Investigación en Ciencias de la Alimentación (CSIC-UAM) , Madrid, Spain .
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: de la Fuente
mesh_terms: D000328:Adult; D001942:Breast Feeding; D003611:Dairy Products; D004032:Diet; D004041:Dietary Fats; D002149:Energy Intake / Q000502:physiology; D005247:Feeding Behavior; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007774:Lactation; D039382:Maternal Nutritional Physiological Phenomena; D008895:Milk, Human / Q000737:chemistry*; D009035:Mothers; D009549:Nigeria; D009753:Nutritive Value; D012424:Rural Population; D044242:Trans Fatty Acids / Q000032:analysis* / Q000737:chemistry*; D014505:Urban Population
chemical_list: D004041:Dietary Fats; D044242:Trans Fatty Acids
keywords: fatty acid; human milk; trans 18:1