title: Lower Jump Power Rather Than Muscle Mass Itself is Associated with Vertebral Fracture in Community-Dwelling Elderly Korean Women.
abstract: Sarcopenia is considered to be a risk factor for osteoporotic fracture, which is a major health problem in elderly women. In this study, we aimed to investigate the association of sarcopenia, with regard to muscle mass and function, with prevalent vertebral fracture in community-dwelling elderly women. We recruited 1281 women aged 64 to 87 years from the Korean Urban Rural Elderly cohort study. Muscle mass and function were measured using bioimpedance analysis and jumping mechanography. Skeletal muscle index (SMI) and jump power were used as an indicator of muscle mass and function, respectively. Among the participants, we observed 282 (18.9%) vertebral fractures and 564 (44.0%) osteoporosis. Although age, body mass index, and prevalence of osteoporosis increased as both SMI and jump power decreased, prevalence of vertebral fracture increased only when jump power decreased. In univariate analysis, compared with the highest quartile of jump power, the lowest quartile had a significant odds ratio of 2.80 (95% CI 1.79-4.36) for vertebral fracture. This association between jump power and vertebral fracture remained significant, with an odds ratio of 3.04 (95% CI 1.77-5.23), even after adjusting for other risk factors including age, bone mineral density, previous fracture, and cognitive function. In contrast, there was no association between SMI and vertebral fracture. Based on our results, low jump power, but not SMI, is associated with vertebral fracture in community-dwelling elderly Korean women. This finding suggests that jump power may have a more important role than muscle mass itself for osteoporotic fracture.
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Lee
authors.affiliation: Division of Endocrinology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.|Department of Medicine, Yonsei University Graduate School of Medicine, Seoul, Republic of Korea.
authors.forename: Su Jin
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Kyoung Min
authors.initials: KM
authors.lastname: Kim
authors.affiliation: Department of Medicine, Yonsei University Graduate School of Medicine, Seoul, Republic of Korea.|Division of Endocrinology and Metabolism, Department of Internal Medicine, Inha University School of Medicine, Incheon, Republic of Korea.
authors.forename: Da Hea
authors.initials: DH
authors.lastname: Seo
authors.affiliation: Department of Sociology, Yonsei University, Seoul, Republic of Korea.
authors.forename: Seung Won
authors.initials: SW
authors.lastname: Lee
authors.affiliation: Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Han Sol
authors.initials: HS
authors.lastname: Choi
authors.affiliation: Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Hyeon Chang
authors.initials: HC
authors.lastname: Kim
authors.affiliation: Department of Sociology, Yonsei University, Seoul, Republic of Korea.
authors.forename: Yoosik
authors.initials: Y
authors.lastname: Youm
authors.affiliation: Division of Geriatrics, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Chang Oh
authors.initials: CO
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Severance Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. yumie@yuhs.ac.
authors.forename: Yumie
authors.identifier: 0000-0003-4227-5638
authors.initials: Y
authors.lastname: Rhee
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D015519:Bone Density / Q000502:physiology; D015331:Cohort Studies; D015444:Exercise; D005260:Female; D006801:Humans; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D009135:Muscular Diseases / Q000453:epidemiology; D010024:Osteoporosis / Q000150:complications / Q000453:epidemiology*; D058866:Osteoporotic Fractures / Q000453:epidemiology*; D015995:Prevalence; D055948:Sarcopenia / Q000453:epidemiology* / Q000503:physiopathology; D016103:Spinal Fractures / Q000453:epidemiology*
keywords: Elderly; Fracture; Jump power; Osteoporosis; Sarcopenia