title: Quantitative EEG for Predicting Upper Limb Motor Recovery in Chronic Stroke Robot-Assisted Rehabilitation.
abstract: Stroke is a leading cause for adult disability, which in many cases causes motor deficits. Despite the developments in motor rehabilitation techniques, recovery of upper limb functions after stroke is limited and heterogeneous in terms of outcomes, and knowledge of important factors that may affect the outcome of the therapy is necessary to make a reasonable prediction for individual patients. In this paper, we assessed the relationship between quantitative electroencephalographic (QEEG) measures and the motor outcome in chronic stroke patients that underwent a robot-assisted rehabilitation program to evaluate the utility of QEEG indices to predict motor recovery. For this purpose, we acquired resting-state electroencephalographic signals from which the power ratio index (PRI), delta/alpha ratio, and brain symmetry index were calculated. The outcome of the motor rehabilitation was evaluated using upper limb section of the Fugl-Meyer Assessment. We found that PRI was significantly correlated with the motor recovery, suggesting that this index may provide useful information to predict the rehabilitation outcome.
authors.forename: Paula
authors.initials: P
authors.lastname: Trujillo
authors.forename: Alfonso
authors.initials: A
authors.lastname: Mastropietro
authors.forename: Alessandro
authors.initials: A
authors.lastname: Scano
authors.forename: Andrea
authors.initials: A
authors.lastname: Chiavenna
authors.forename: Simona
authors.initials: S
authors.lastname: Mrakic-Sposta
authors.forename: Marco
authors.initials: M
authors.lastname: Caimmi
authors.forename: Franco
authors.initials: F
authors.lastname: Molteni
authors.forename: Giovanna
authors.initials: G
authors.lastname: Rizzo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015915:Motion Therapy, Continuous Passive / Q000379:methods*; D009069:Movement Disorders / Q000175:diagnosis* / Q000534:rehabilitation*; D015203:Reproducibility of Results; D012371:Robotics / Q000379:methods*; D012680:Sensitivity and Specificity; D020521:Stroke / Q000150:complications / Q000175:diagnosis; D000071939:Stroke Rehabilitation / Q000379:methods*; D034941:Upper Extremity