title: Ovarian cancer with metastatic inguinal lymphadenopathy: A case series and literature review.
abstract: BACKGROUND
  Ovarian cancer is the 4th commonest cancer among Egyptian women. It can spread through 3 different lymphatic pathways to para-aortic/paracaval lymph nodes, to pelvic lymph nodes and only occasionally through the round ligament of the uterus to the inguinal nodes. These rare cases are staged IVb on FIGO system.
  
  
  METHODS
  We present a series of 4 cases of ovarian cancer metastasizing to inguinal nodes. The literature review revealed only 17 published similar cases. Management controversies as well as prognosis are discussed in our study.
  
  
  CONCLUSIONS
  Inguinal metastasis from ovarian cancer seems more frequent than previously thought. Examination of inguinal region should be mandatory in all cases diagnosed with ovarian cancer.
authors.affiliation: Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Egypt. Electronic address: drislamhany@mans.edu.eg.
authors.forename: Islam H
authors.initials: IH
authors.lastname: Metwally
authors.affiliation: Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Egypt.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zuhdy
authors.affiliation: Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Egypt.
authors.forename: Amr
authors.initials: A
authors.lastname: Hassan
authors.affiliation: Medical Oncology Department, Oncology Center Mansoura University (OCMU), Egypt.
authors.forename: Reham
authors.initials: R
authors.lastname: Alghandour
authors.affiliation: Pathology Department, Faculty of Medicine, Mansoura University, Egypt.
authors.forename: Nirmeen
authors.initials: N
authors.lastname: Megahed
mesh_terms: D000368:Aged; D004534:Egypt; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D000072281:Lymphadenopathy / Q000453:epidemiology / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000473:pathology*; D011379:Prognosis
keywords: Inguinal lymph node metastasis; Lymphatic spread; Ovarian cancer; Stage IV