title: Aquaporins and Gland Secretion.
abstract: Aquaporins (AQPs ) are expressed in most exocrine and endocrine secretory glands. Consequently, summarizing the expression and functions of AQPs in secretory glands represents a daunting task considering the important number of glands present in the body, as well as the number of mammalian AQPs - thirteen. The roles played by AQPs in secretory processes have been investigated in many secretory glands. However, despite considerable research, additional studies are clearly needed to pursue our understanding of the role played by AQPs in secretory processes. This book chapter will focus on summarizing the current knowledge on AQPs expression and function in the gastrointestinal tract , including salivary glands, gastric glands, Duodenal Brunner's gland, liver and gallbladder, intestinal goblets cells, exocrine and endocrine pancreas, as well as few other secretory glands including airway submucosal glands, lacrimal glands, mammary glands and eccrine sweat glands.
authors.affiliation: Laboratory of Pathophysiological and Nutritional Biochemistry, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium. cdelport@ulb.ac.be.
authors.forename: Christine
authors.initials: C
authors.lastname: Delporte
mesh_terms: D000818:Animals; D020346:Aquaporins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D001692:Biological Transport; D002011:Brunner Glands / Q000378:metabolism; D005057:Eukaryotic Cells / Q000166:cytology / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D015870:Gene Expression; D006801:Humans; D007515:Islets of Langerhans / Q000378:metabolism; D007765:Lacrimal Apparatus / Q000378:metabolism; D042361:Mammary Glands, Human / Q000378:metabolism*; D046790:Pancreas, Exocrine / Q000378:metabolism; D021122:Protein Subunits / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012469:Salivary Glands / Q000378:metabolism*; D013545:Sweat Glands / Q000378:metabolism
chemical_list: D020346:Aquaporins; D021122:Protein Subunits
keywords: Aquaporins; Endocrine glands; Exocrine glands; Expression; Function; Secretion