title: A Case of Nuclear Protein in Testis Midline Carcinoma Arising From the Submandibular Gland Duct in a Pregnant Patient.
abstract: This report describes the first reported case of a nuclear protein in testis midline carcinoma (NMC) arising from the submandibular gland (SMG) duct in a pregnant woman. A 29-year-old pregnant woman presented with a left-side mass in the floor of the mouth. An NMC arising from the SMG duct was confirmed by excisional biopsy examination. Intensive treatment, including surgery and chemotherapy, was provided without termination of the pregnancy. Additional chemotherapy and radiotherapy were provided after delivery. The treatment was successful. Neither the patient nor her infant had any complications and the patient remained disease free 20 months after her initial surgery. This report describes the successful diagnosis and treatment of a rare presentation of an NMC of the SMG duct in a pregnant woman.
authors.affiliation: Resident, Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Korea.
authors.forename: Younghoon
authors.initials: Y
authors.lastname: Cho
authors.affiliation: Associate Professor, Department of Internal Medicine and Cancer Research Center, Seoul National University Hospital, Seoul, Korea.
authors.forename: Bhum Suk
authors.initials: BS
authors.lastname: Keam
authors.affiliation: Professor, Department of Pathology and Medical Research Center, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Kyeong Cheon
authors.initials: KC
authors.lastname: Jung
authors.affiliation: Clinical Fellow, Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Korea. Electronic address: bohae111@naver.com.
authors.forename: Bo Hae
authors.initials: BH
authors.lastname: Kim
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000628:therapy*; D013365:Submandibular Gland Neoplasms / Q000473:pathology / Q000628:therapy*
chemical_list: D014408:Biomarkers, Tumor