title: Incidence trends in oesophageal cancer by histological type: An updated analysis in Sweden.
abstract: We aimed to update incidence trends of oesophageal cancer by histological type in Sweden.
  
  
  
  Using data from the Swedish Cancer Registry, we examined incidence trends of oesophageal cancer by histological types in individuals aged ≥50 years in 1970-2014 using log-linear joinpoint regressions.
  
  
  
  The age-standardised incidence rate of oesophageal adenocarcinoma in men increased on average by 3.0% per year in 1970-1994, followed by a more rapid increase of 13.7% per year in 1994-2000, and a slower increase of 2.6% per year in 2010-2014. The rate of oesophageal adenocarcinoma in women increased on average by 4.2% per year during the entire period. The rate of squamous cell carcinoma generally decreased over the past 2-3 decades in both sexes.
  
  
  
  The incidence of oesophageal adenocarcinoma continues to rise in Sweden, although the increase seems to have slowed down in men since 2000. The incidence of oesophageal squamous cell carcinoma is decreasing.
authors.affiliation: Upper Gastrointestinal Surgery, Department of Molecular medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. Electronic address: shaohua.xie@ki.se.
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Xie
authors.affiliation: Upper Gastrointestinal Surgery, Department of Molecular medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Fredrik
authors.initials: F
authors.lastname: Mattsson
authors.affiliation: Upper Gastrointestinal Surgery, Department of Molecular medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden; Division of Cancer Studies, King's College, London, United Kingdom.
authors.forename: Jesper
authors.initials: J
authors.lastname: Lagergren
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology* / Q000473:pathology; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D013548:Sweden / Q000453:epidemiology
keywords: Adenocarcinoma; Incidence; Oesophageal cancer; Oesophageal neoplasm; Squamous cell carcinoma; Time trends