title: Boundary element simulation of ultrasonic backscattering during the fracture healing process.
abstract: Competent fracture healing monitoring and treatment requires an extensive knowledge of bone biology and microstructure. The use of non-invasive and non-radiating means for the monitoring of the bone healing process has gained significant interest in recent years. Ultrasound is considered as a modality which can contribute to the assessment of bone status during the healing process, as well as, enhance the rate of the tissues' ossification. This work presents boundary element simulations of ultrasound propagation in healing long bones to investigate the monitoring potential of backscattering parameters. The interaction of a plane wave at 100 kHz with the bone and the callus is examined by calculating the acoustic pressure and scattering amplitude in the backward direction. Callus is considered as a two-dimensional, non-homogeneous medium consisted of multiple layers with evolving material properties. It was shown that the backscattering parameters could potentially reflect the fracture healing progress.
authors.forename: Vassiliki T
authors.initials: VT
authors.lastname: Potsika
authors.forename: Konstantinos N
authors.initials: KN
authors.lastname: Grivas
authors.forename: Theodoras
authors.initials: T
authors.lastname: Gortsas
authors.forename: Vasilios C
authors.initials: VC
authors.lastname: Protopappas
authors.forename: Demosthenes K
authors.initials: DK
authors.lastname: Polyzos
authors.forename: Dimitrios I
authors.initials: DI
authors.lastname: Fotiadis
mesh_terms: D000818:Animals; D002146:Bony Callus / Q000000981:diagnostic imaging*; D017102:Fracture Healing; D006801:Humans; D008954:Models, Biological; D008991:Monitoring, Physiologic / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*