title: Nanoengineering of Core-Shell Magnetic Mesoporous Microspheres with Tunable Surface Roughness.
abstract: Functional core-shell mesoporous microspheres with integrated functions, controlled structure, and surface properties and morphologies have received increasing attention due to their excellent physicochemical properties. Herein, core-shell magnetic mesoporous materials with cauliflower-like morphology and tunable surface roughness have been synthesized through a kinetics-controlled interface co-assembly and deposition of mesostructured nanocomposites on Fe3O4@RF microspheres (RF refers to resorcinol formaldehyde resin). The obtained microspheres, synthesized via this interface nanoengineering method, possess well-defined sandwich structure with a tunable rough morphology, uniform size (560-1000 nm), perpendicularly aligned mesopores (∼5.7 nm) in the outer shell, RF-protected magnetic responsive core, high surface area up to 382 m2/g, and large pore volume of 0.66 cm3/g. As a result of the unique surface features and magnetic properties, these microspheres exhibit excellent performance in stabilizing and oxygen-free manipulating aqueous solutions in petroleum ether by a magnetic field. They also exhibit superior cell uptake properties compared with traditional smooth core-shell magnetic mesoporous silica microspheres, opening up the possible applications in fast drug delivery in cancer therapy.
authors.affiliation: Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, iChEM, Fudan University , Shanghai 200433, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Yue
authors.affiliation: Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, iChEM, Fudan University , Shanghai 200433, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Pancreatic Surgery, Huashan Hospital, Fudan University , Shanghai 200040, China.
authors.forename: Yongjian
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, iChEM, Fudan University , Shanghai 200433, China.
authors.forename: Jialuo
authors.initials: J
authors.lastname: Li
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology, The University of Queensland , Brisbane, Queensland 4072, Australia.
authors.forename: Hongwei
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology, The University of Queensland , Brisbane, Queensland 4072, Australia.
authors.forename: Chengzhong
authors.identifier: 0000-0003-3707-0785
authors.initials: C
authors.lastname: Yu
authors.affiliation: Materials Science and Technology Program, College of Arts and Sciences, Qatar University , PO Box 2713, Doha, Qatar.
authors.forename: Ahmed A
authors.identifier: 0000-0002-7291-5723
authors.initials: AA
authors.lastname: Elzatahry
authors.affiliation: Department of Chemistry, College of Science, King Saud University , Riyadh 11451, Saudi Arabia.
authors.forename: Abdulaziz
authors.initials: A
authors.lastname: Alghamdi
authors.affiliation: Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, iChEM, Fudan University , Shanghai 200433, China.|State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences , Shanghai 200050, China.
authors.forename: Yonghui
authors.identifier: 0000-0002-0657-9397
authors.initials: Y
authors.lastname: Deng
authors.affiliation: Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, iChEM, Fudan University , Shanghai 200433, China.
authors.forename: Dongyuan
authors.identifier: 0000-0001-8440-6902
authors.initials: D
authors.lastname: Zhao