title: [Application of exfoliated cells in early diagnosis of oral cancer].
abstract: Exfoliative cytology is a simple and non-invasive examination method that is easily accepted by the patient. A number of new techniques are used to further increase the accuracy of sample collecting. It is widely used in the detection of cervical, oral cavity and various coelom exfoliated cells. This article reviews the development of exfoliative cytology in oral cancer diagnosis. It is realized that the qualitative and quantitative analysis of cancer and precancerous lesions, through DNA quantitative analysis to calculate DNA index (DI value), multiple parameter analysis and statistical modeling calculation to evaluate oral cancer risk index (OCRI) of the patient has great significance in cancer screening, early diagnosis and prognosis review, especially in the field of oral cancer.
authors.affiliation: Department of Oral Medicine, Capital Medical University School of Stomatology, Beijing 100050, China.
authors.forename: T
authors.initials: T
authors.lastname: Liu
authors.affiliation: Institute of Dental Research, Capital Medical University School of Stomatology, Beijing 100050, China.
authors.forename: X Y
authors.initials: XY
authors.lastname: Zhang
authors.affiliation: Department of Oral Medicine, Capital Medical University School of Stomatology, Beijing 100050, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Sun
mesh_terms: D003581:Cytodiagnosis / Q000379:methods*; D004273:DNA, Neoplasm / Q000032:analysis; D055088:Early Detection of Cancer; D006801:Humans; D009062:Mouth Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D012306:Risk
chemical_list: D004273:DNA, Neoplasm
keywords: Early diagnosis; Exfoliated cells; Mouth neoplasms