title: Discernment scheme for paraquat poisoning: A five-year experience in Shiraz, Iran.
abstract: OBJECTIVE
  To evaluate various schemes for paraquat poisoning and different variables that influence the outcome of acute paraquat poisoning.
  
  
  METHODS
  In a cross-sectional study, the information about all cases of acute paraquat poisoning who were admitted to teaching hospitals affiliated to Shiraz University of Medical Sciences, in a five year period (September 2010 to September 2015) were evaluated. The variables included: Demographic data, medical assessment, therapeutic options, laboratory findings, and the outcomes. Data were analyzed using SPSS, version 22. Significant difference between groups was tested using t-test for continues outcomes andχ2test for categorical. The significance level was considered to beP< 0.05.
  
  
  RESULTS
  A total of 104 patients (66.3% male) were evaluated. The mean age of the female patients was 22.81 ± 9.87 years and the male patients' was 27.21 ± 11.06 years. Ninety seven (93.3%) of all the cases were suicide attempts with mortality rate of 43.2%. Despite the necessity for emergency hemodialysis during the first 6 h of intoxication, none of the patients had dialysis during this time. Immunosuppressive and corticosteroid medications were not administrated in adequate dosage in 31.1% and 60% of the patients, respectively. Ingestion of more than 22.5 cc of paraquat and increase in creatinine level were the most important predictors of mortality.
  
  
  CONCLUSIONS
  Treatment should start immediately for these patients. Moreover, creating a clinical guideline according to the findings can have an impact on the treatment procedure which seems to be necessary.
authors.affiliation: Saeed Kavousi-Gharbi, Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7134845794, Fars Province, Iran.
authors.forename: Saeed
authors.initials: S
authors.lastname: Kavousi-Gharbi
authors.affiliation: Saeed Kavousi-Gharbi, Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7134845794, Fars Province, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Jalli
authors.affiliation: Saeed Kavousi-Gharbi, Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7134845794, Fars Province, Iran.
authors.forename: Akbar
authors.initials: A
authors.lastname: Rasekhi-Kazerouni
authors.affiliation: Saeed Kavousi-Gharbi, Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7134845794, Fars Province, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Habibagahi
authors.affiliation: Saeed Kavousi-Gharbi, Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7134845794, Fars Province, Iran.
authors.forename: Sayed Mahdi
authors.initials: SM
authors.lastname: Marashi
keywords: Mortality; Paraquat; Poisoning; Prognosis; Suicide