title: Importance of metabolism variations in a model of extracorporeal carbon dioxide removal.
abstract: Extracorporeal CO2 Removal device is used in clinics when a patient suffers from a pulmonary insufficiency like Acute Respiratory Distress Syndrome and allows to decarboxylate blood externally. In this work, a model of the respiratory system coupled with such a device is proposed to analyze the decrease of CO2 partial pressure in blood. To validate the model, some parameters are estimated thanks to experimental data. Metabolism is a crucial parameter and we show that its time evolution must be taken into account in order to have correct CO2 partial pressure simulations in arteries and in veins.
authors.forename: S
authors.initials: S
authors.lastname: Habran
authors.forename: T
authors.initials: T
authors.lastname: Desaive
authors.forename: Ph
authors.initials: P
authors.lastname: Morimont
authors.forename: B
authors.initials: B
authors.lastname: Lambermont
authors.forename: P C
authors.initials: PC
authors.lastname: Dauby
mesh_terms: D055371:Acute Lung Injury / Q000628:therapy; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood*; D015199:Extracorporeal Membrane Oxygenation; D008962:Models, Theoretical; D010101:Oxygen Consumption; D012121:Respiration, Artificial / Q000295:instrumentation / Q000379:methods*; D012128:Respiratory Distress Syndrome / Q000628:therapy; D013552:Swine
chemical_list: D002245:Carbon Dioxide