title: Comprehensive study on the electrocatalytic effect of copper - doped nano-clinoptilolite towards amoxicillin at the modified carbon paste electrode - solution interface.
abstract: In this work, Cu(II)-exchanged clinoptilolite nanoparticles (Cu(II)-NCL) were prepared and characterized by FTIR, BET, XRD and TEM techniques. The obtained Cu(II)-NCL was then used for the modification of carbon paste electrode (CPE). The resulted Cu(II)-NCL/CPE was finally used for the voltammetric determination of amoxicillin (AMX). The best voltammetric response was obtained by the electrode containing 20% of the modifier in 0.05molL-1NaCl at pHs 2.2 and 7.2. The electrode showed a linear response in the concentration range of 4.0×10-8-1.0×10-4molL-1AMX with a detection limit of 2.0×10-8molL-1in square wave voltammetry. The electrode showed good repeatability, reproducibility, long life time confirmed by statistical tests. The electrode had also good selectivity together with good applicability in determination of AMX in urine and pharmaceutical tablets as real samples.
authors.affiliation: Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan, Iran; Young Researchers and Elite Club, Shahreza Branch, Islamic Azad University, Shahreza, Iran.
authors.forename: Motahare
authors.initials: M
authors.lastname: Nosuhi
authors.affiliation: Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan, Iran; Young Researchers and Elite Club, Shahreza Branch, Islamic Azad University, Shahreza, Iran; Razi Chemistry Research Center (RCRC), Shahreza Branch, Islamic Azad University, Isfahan, Iran. Electronic address: arnezamzadeh@iaush.ac.ir.
authors.forename: Alireza
authors.initials: A
authors.lastname: Nezamzadeh-Ejhieh
mesh_terms: D000658:Amoxicillin / Q000737:chemistry* / Q000652:urine; D002244:Carbon / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D004566:Electrodes; D015203:Reproducibility of Results; D013607:Tablets / Q000737:chemistry; D017641:Zeolites / Q000737:chemistry*
chemical_list: D013607:Tablets; C083175:clinoptilolite; D017641:Zeolites; D002244:Carbon; D003300:Copper; D000658:Amoxicillin
keywords: Amoxicillin; Carbon paste; Clinoptilolite; Nano; Voltammetry; Zeolite modified electrodes