title: Correlation of benign prostatic obstruction-related complications with clinical outcomes in patients after transurethral resection of the prostate.
abstract: We aim to investigate the correlation of benign prostatic obstruction (BPO)-related complications with clinical outcomes in patients after transurethral resection of the prostate in China. We reviewed the medical history of all patients who underwent surgery from 1992 to 2013. We assessed the preoperative clinical profile, clinical management, and operative complications. Overall, 2271 patients were enrolled in the study. Of these patients, 1193 (52.5%) had no BPO-related complications and 1078 (46.3%) had BPO-related complications. Compared with patients without BPO-related complications, those with BPO-related complications were older (p = 0.001) and usually had other urologic comorbidities (p = 0.003). Additionally, they tended to have more tissue resected (p < 0.001), a higher American Society of Anesthesiologists grade (p = 0.002), and larger prostates (p < 0.001). Nonetheless, there was no obvious difference in surgical complications between both groups (p > 0.05). Among patients with BPO-related complications, compared with the bladder stone group, only the bladder stone+ group tended to have a greater urinary infection risk after transurethral resection of the prostate. Compared with patients with one or two BPO-related complications, those with three BPO-related complications tended to have a higher risk of pulmonary embolism and acute coronary syndrome (p < 0.05). Despite the widespread use of medication, patients with BPO-related complications were older and had larger prostates; however, transurethral resection of the prostate is still considered a safe and recommended surgical treatment. Nevertheless, those with three or more complications were at a higher risk of severe complication after surgery, and active surgical intervention is needed once BPO-related complications develop.
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
authors.forename: Run-Qi
authors.initials: RQ
authors.lastname: Guo
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Yu
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
authors.forename: Yi-Sen
authors.initials: YS
authors.lastname: Meng
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China. Electronic address: kaizhangpku@163.com.
authors.forename: Kai
authors.initials: K
authors.lastname: Zhang
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
authors.forename: Ben
authors.initials: B
authors.lastname: Xu
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
authors.forename: Yun-Xiang
authors.initials: YX
authors.lastname: Xiao
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
authors.forename: Shi-Liang
authors.initials: SL
authors.lastname: Wu
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, National Research Center for Genitourinary Oncology, Beijing, China.
authors.forename: Bai-Nian
authors.initials: BN
authors.lastname: Pan
mesh_terms: D054058:Acute Coronary Syndrome / Q000209:etiology / Q000473:pathology; D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011183:Postoperative Complications / Q000473:pathology; D011467:Prostate / Q000473:pathology / Q000601:surgery*; D011470:Prostatic Hyperplasia / Q000150:complications / Q000473:pathology / Q000601:surgery*; D011655:Pulmonary Embolism / Q000209:etiology / Q000473:pathology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013927:Thrombosis / Q000209:etiology / Q000473:pathology; D020728:Transurethral Resection of Prostate / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome; D001744:Urinary Bladder Calculi / Q000150:complications / Q000473:pathology / Q000601:surgery*; D014563:Urodynamics
keywords: Benign prostatic hyperplasia; Complication; Transurethral resection of the prostate; Treatment outcome