title: Personal Activity Intelligence (PAI), Sedentary Behavior and Cardiovascular Risk Factor Clustering - the HUNT Study.
abstract: Prolonged sedentary behavior (SB) positively associates with clustering of risk factors for cardiovascular disease (CVD). The recently developed metric for physical activity (PA) tracking called Personal Activity Intelligence (PAI) takes into account age, sex, resting and maximum heart rate, and a score of ≥100 weekly PAI has been shown to reduce the risk of premature CVD death in healthy as well as individuals with known CVD risk factors, regardless of whether or not the current PA recommendations were met. The aim of the present study was to examine if PAI modifies the associations between SB and CVD risk factor (CV-RF) clustering in a large apparently healthy general population cohort (n=29,950, aged ≥20 years). Logistic regression revealed that in those with ≥100 weekly PAI, the likelihood of CV-RF clustering prevalence associated with prolonged SB was attenuated across age groups. Monitoring weekly PAI-level could be useful to ensure that people perform enough PA to combat SB's deleterious association with CV-RF.
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway.
authors.forename: Nina
authors.initials: N
authors.lastname: Zisko
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway.
authors.forename: Kjerstin Næss
authors.initials: KN
authors.lastname: Skjerve
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway.
authors.forename: Atefe R
authors.initials: AR
authors.lastname: Tari
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway.
authors.forename: Silvana Bucher
authors.initials: SB
authors.lastname: Sandbakk
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway; School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Queensland, Australia.
authors.forename: Ulrik
authors.initials: U
authors.lastname: Wisløff
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway; Department of Cardiology, St. Olavs Hospital, Norway. Electronic address: bjarne.nes@ntnu.no.
authors.forename: Bjarne M
authors.initials: BM
authors.lastname: Nes
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Faculty of Medicine, Trondheim, Norway; Department of Cardiology, St. Olavs Hospital, Norway.
authors.forename: Javaid
authors.initials: J
authors.lastname: Nauman
keywords: Cardiovascular disease; Cardiovascular disease risk factors; Exercise; Exercise intensity; Physical activity; Sedentary behavior