title: The effect of allergic rhinitis with positive skin prick test on choroidal thickness.
abstract: Allergic rhinitis is an inflammatory disease that develops through immunoglobulin E in the rhino-ocular mucosa due to allergy. The main symptoms are runny nose, nasal congestion, sneezing and itchy nose. This study was designed to investigate the effect of allergic rhinitis on choroidal thickness. This study was planned as a case-control study. This study performed in a tertiary referral center. The study included 61 patients with allergic rhinitis and 35 healthy subjects. Patients in both groups underwent skin prick test. In allergic rhinitis patients and healthy persons; subfoveal, temporal and nasal choroidal thickness measurement was performed. The choroidal thicknesses were measured without pupil dilation using the Spectralis Optical Coherence Tomography. In the subfoveal and temporal region, choroidal tissue was followed up significantly thicker in allergic rhinitis patients statistically compared to healthy persons (p = 0.031, p = 0.049). However, no significant difference was followed up between the nasal choroidal thickness measurements statistically (p = 0.54). Runny nose (67.2%), sneeze (65.5%), stuffiness (62.2%), itching of the nose (40.9%), and nasal discharge (21.3%) complaints were observed significantly higher in the group having allergic rhinitis. The effect of allergic rhinitis on choroidal thickness were assessed and compared with the control group. Our study revealed that there was significant association between increased choroidal thickness and allergic rhinitis. Allergic sensitivity may play an important role in increased choroidal thickness.
authors.affiliation: Bezmialem Vakif University, Faculty of Medicine, Department of Otorhinolaryngology, Adnan Menderes Boulevard, Vatan Street, Fatih, 34093, Istanbul, Turkey. alperyenigun@gmail.com.
authors.forename: Alper
authors.initials: A
authors.lastname: Yenigun
authors.affiliation: Bezmialem Vakif University, Faculty of Medicine, Department of Ophthalmology, Fatih, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Elbay
authors.affiliation: Bezmialem Vakif University, Faculty of Medicine, Department of Otorhinolaryngology, Adnan Menderes Boulevard, Vatan Street, Fatih, 34093, Istanbul, Turkey.
authors.forename: Remzi
authors.initials: R
authors.lastname: Dogan
authors.affiliation: Bezmialem Vakif University, Faculty of Medicine, Department of Otorhinolaryngology, Adnan Menderes Boulevard, Vatan Street, Fatih, 34093, Istanbul, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Ozturan
authors.affiliation: Bezmialem Vakif University, Faculty of Medicine, Department of Ophthalmology, Fatih, Istanbul, Turkey.
authors.forename: Mehmet Hakan
authors.initials: MH
authors.lastname: Ozdemir
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002829:Choroid / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000000981:diagnostic imaging / Q000473:pathology; D065631:Rhinitis, Allergic / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D012882:Skin Tests / Q000379:methods*; D013223:Statistics as Topic; D041623:Tomography, Optical Coherence / Q000379:methods; D014421:Turkey / Q000453:epidemiology
keywords: Allergic reaction; Allergic rhinitis; Allergy; Choroid; Immunoglobulin E; Optical coherence tomography; Prevalence; Skin tests