title: Granulomatosis with Polyangiitis (Wegener Granulomatosis) with Unusual Presentation.
abstract: We came across a 32 years old male admitted in our hospital with prolonged low-grade fever, haemoptysis, leg swelling, weight loss, purpuric rashes and malaena. He received anti-TB treatment at another hospital without any improvement. He was pale with bullous and purpuric lesions over legs and feet. He also had features of consolidation over both lung fields. His CRP was 312mg/L, Urine R/M/E showed 40-50 RBC/HPF, Chest X-ray showed features of bilateral consolidation, c-ANCA-10U/L (positive); Tracheal aspirate for AFB was found to be negative. We diagnosed the case as Granulomatosis with Polyangitis (WG) and started treatment with steroid and cyclophosphamide. But the patient could not be saved probably due to delay in starting management.
authors.affiliation: Dr MA Mannan, Consultant, ICU, Dr Sirajul Islam Medical College & Hospital, Dhaka, Bangladesh.
authors.forename: M A
authors.initials: MA
authors.lastname: Mannan
authors.forename: K
authors.initials: K
authors.lastname: Pasha
authors.forename: S
authors.initials: S
authors.lastname: Nahar
authors.forename: K
authors.initials: K
authors.lastname: Begum
mesh_terms: D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic; D003520:Cyclophosphamide / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008168:Lung; D008297:Male; D011859:Radiography
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide