title: Ligand-free Cu(ii)-mediated aerobic oxidations of aldehyde hydrazones leading to N,N'-diacylhydrazines and 1,3,4-oxadiazoles.
abstract: A Cu(ii)-mediated synthesis of N,N'-diacylhydrazines and 1,3,4-oxadiazoles from aldehyde hydrazones has been developed. This is the first time that the synthesis of N,N'-diacylhydrazines and 1,3,4-oxadiazoles using N,N-dimethylamides as the acylation reagent and O2in air as the oxidation reagent is reported. These reactions offered several advantages including simple workups, ligand-free inexpensive metal salts as mediators, high yields, and wide scope of substrates.
authors.affiliation: Department of Chemistry, School of Science, Tianjin University, 135 Yaguan Road, Jinnan District, Tianjin 300354, P. R. China. liuleiorgchem@163.com.
authors.forename: Lei
authors.identifier: http://orcid.org/0000-0003-2529-137X
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Chemistry, School of Science, Tianjin University, 135 Yaguan Road, Jinnan District, Tianjin 300354, P. R. China. liuleiorgchem@163.com.
authors.forename: Suliu
authors.initials: S
authors.lastname: Feng