title: Fast analytical spectral filtering methods for magnetic resonance perfusion quantification.
abstract: The deconvolution in the perfusion weighted imaging (PWI) plays an important role in quantifying the MR perfusion parameters. The PWI application to stroke and brain tumor studies has become a standard clinical practice. The standard approach for this deconvolution is oscillatory-limited singular value decomposition (oSVD) and frequency domain deconvolution (FDD). The FDD is widely recognized as the fastest approach currently available for deconvolution of MR perfusion data. In this work, two fast deconvolution methods (namely analytical fourier filtering and analytical showalter spectral filtering) are proposed. Through systematic evaluation, the proposed methods are shown to be computationally efficient and quantitatively accurate compared to FDD and oSVD.
authors.forename: Kasireddy V
authors.initials: KV
authors.lastname: Reddy
authors.forename: Abhishek
authors.initials: A
authors.lastname: Mitra
authors.forename: Phaneendra K
authors.initials: PK
authors.lastname: Yalavarthy
mesh_terms: D001783:Blood Flow Velocity; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D010477:Perfusion; D020521:Stroke / Q000000981:diagnostic imaging*