title: The Compress® transcutaneous implant for rehabilitation following limb amputation.
abstract: Amputation is an unfortunate outcome of a variety of orthopedic conditions. Many amputees can be functionally fitted with conventional suspension sockets. A substantial subset, however, fails this conventional treatment and is unable to function. In Europe, an alternative to socket-based prostheses has been available for 25 years. Patients there who are unable to functionally use socket-based prostheses have been offered the possibility for transcutaneous osseointegration. With this technology, the prosthetic limb can be rigidly attached to the residual bone, and the socket is eliminated, in many cases enabling improved function and patient satisfaction. In the United States, regulatory barriers have greatly limited the adoption and acceptance of transdermal osseointegration. The Compress® device was developed as an alternate means of fixation for massive endoprostheses, such as distal femoral replacements. A uniquely designed prosthesis is rigidly anchored to the end of the cortical bone and is then subjected to a large axial stress. The bone then grows avidly into the device, providing permanent osseointegration. We have recently adopted this device for transcutaneous use. These procedures have been performed in the United States on a custom regulatory basis. Results of this have been encouraging, and we are planning to begin a regulatory trial in the near future.
authors.affiliation: The University of Pittsburgh Medical Center, 5200 Centre Avenue, 15232, Suite 415 Pittsburgh, PA, USA. mcgoughrl@upmc.edu.
authors.forename: R L
authors.initials: RL
authors.lastname: McGough
authors.affiliation: The University of Pittsburgh Medical Center, 5200 Centre Avenue, 15232, Suite 415 Pittsburgh, PA, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Goodman
authors.affiliation: University of Utah, Salt Lake City, Utah, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Randall
authors.affiliation: Walter Reed Naval Military Medical Center, Bethesda, Maryland, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Forsberg
authors.affiliation: Walter Reed Naval Military Medical Center, Bethesda, Maryland, USA.
authors.forename: B K
authors.initials: BK
authors.lastname: Potter
authors.affiliation: West Virginia University, Morgantown, West Virginia, USA.
authors.forename: B
authors.initials: B
authors.lastname: Lindsey
mesh_terms: D000328:Adult; D000368:Aged; D000671:Amputation, Surgical / Q000534:rehabilitation*; D000672:Amputation Stumps; D001186:Artificial Limbs; D019317:Evidence-Based Medicine; D000067190:Exoskeleton Device; D005260:Female; D006801:Humans; D007866:Leg / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000379:methods*; D016896:Treatment Outcome
keywords: Artificial limbs; Femur; Humerus; Prostheses and implants; Quality of life