title: A new norsesquiterpene from the roots of Polyalthia laui.
abstract: One new norsesquiterpene polyalone A (1), and one new natural product 9-keto-cyclocolorenone (2), along with three known analogues (3-5) were isolated from the roots of Polyalthia laui. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their cytotoxic activities and antibacterial activities.
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Zhang-Xin
authors.initials: ZX
authors.lastname: Yu
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Ming-Ye
authors.initials: MY
authors.lastname: Zhuo
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Xiao-Bao
authors.initials: XB
authors.lastname: Li
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Yan-Hui
authors.initials: YH
authors.lastname: Fu
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Guang-Ying
authors.initials: GY
authors.lastname: Chen
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Song
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.|b School of Biochemical Engineering , Hainan Institute of Science and Technology , Haikou , China.
authors.forename: Chang-Ri
authors.initials: CR
authors.lastname: Han
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Xin-Ming
authors.initials: XM
authors.lastname: Song
authors.affiliation: a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
authors.forename: Qi-Jing
authors.initials: QJ
authors.lastname: Fan
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis / Q000494:pharmacology; D003603:Cytotoxins / Q000032:analysis / Q000302:isolation & purification; D006801:Humans; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D031044:Polyalthia / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D003603:Cytotoxins; D012717:Sesquiterpenes; C007186:cyclocolorenone
keywords: Polyalthia laui; antibacterial activities; cytotoxic activities; norsesquiterpene; polyalone A