title: Intralymphatic Histiocytosis: A Report of 2 Cases.
abstract: Intralymphatic histiocytosis is a benign condition characterized by poorly defined erythematous plaques (sometimes forming a reticular pattern) as well as the presence of nodules and vesicles. Its etiology and pathogenesis appear to be related to chronic inflammation in the affected area, prior surgery, or systemic disease, particularly rheumatoid arthritis. We report on 2 new cases, both associated with joint surgery in the affected area and osteoarticular disease (primary synovial osteochondromatosis and rheumatoid arthritis). This is a chronic disease and there is no specific treatment. Different treatment options were chosen in the 2 cases described. A spectacular response to treatment with oral pentoxifylline and topical tacrolimus was observed in 1 of the patients.
authors.affiliation: Servicio de Dermatología, Hospital General de Villarrobledo, Villarrobledo, Albacete, España. Electronic address: m_gomsanchez@hotmail.com.
authors.forename: M E
authors.initials: ME
authors.lastname: Gómez-Sánchez
authors.affiliation: Servicio de Dermatología, Hospital General de Albacete, Albacete, España.
authors.forename: J M
authors.initials: JM
authors.lastname: Azaña-Defez
authors.affiliation: Servicio de Dermatología, Hospital General de Villarrobledo, Villarrobledo, Albacete, España.
authors.forename: M L
authors.initials: ML
authors.lastname: Martínez-Martínez
authors.affiliation: Servicio de Dermatología, Hospital General de Almansa, Almansa, Albacete, España.
authors.forename: M T
authors.initials: MT
authors.lastname: López-Villaescusa
mesh_terms: D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D001172:Arthritis, Rheumatoid / Q000150:complications*; D015838:Chondromatosis, Synovial / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006644:Histiocytes / Q000737:chemistry; D015614:Histiocytosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008206:Lymphatic Diseases / Q000188:drug therapy / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D010431:Pentoxifylline / Q000627:therapeutic use; D017006:Rotator Cuff / Q000601:surgery; D012782:Shoulder; D016559:Tacrolimus / Q000627:therapeutic use
chemical_list: D015703:Antigens, CD; D010431:Pentoxifylline; D016559:Tacrolimus
keywords: Angiomatosis cutánea reactiva; Artritis reumatoide; Histiocitosis intralinfática; Intralymphatic histiocytosis; Reactive cutaneous angiomatosis; Rheumatoid arthritis; Tratamiento; Treatment