title: Complications of Chronic Pancreatitis.
abstract: Chronic pancreatitis is a disease that leads to irreversible changes in the pancreatic morphology and function. The loss of function can lead to diabetes mellitus and exocrine pancreatic insufficiency. The inflammation and fibrosis can also lead to other complications including a chronic abdominal pain syndrome, metabolic bone disease, and pancretic cancer. This article reviews our current understanding of the mechanisms and management of these complications of chronic pancreatitis.
authors.affiliation: Section of Pancreatic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, 410 West Tenth Avenue, Columbus, OH, 3210, USA.
authors.forename: Mitchell L
authors.initials: ML
authors.lastname: Ramsey
authors.affiliation: Section of Pancreatic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, 410 West Tenth Avenue, Columbus, OH, 3210, USA.
authors.forename: Darwin L
authors.initials: DL
authors.lastname: Conwell
authors.affiliation: Section of Pancreatic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, 410 West Tenth Avenue, Columbus, OH, 3210, USA. philip.hart@osumc.edu.
authors.forename: Phil A
authors.initials: PA
authors.lastname: Hart
mesh_terms: D001851:Bone Diseases, Metabolic / Q000209:etiology*; D003920:Diabetes Mellitus / Q000209:etiology*; D010188:Exocrine Pancreatic Insufficiency / Q000209:etiology*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000209:etiology; D010192:Pancreatic Pseudocyst / Q000209:etiology*; D050500:Pancreatitis, Chronic / Q000150:complications*
keywords: Pancreatic cancer; Pancreatic pseudocyst; Pancreatogenic diabetes; Splenic vein thrombus; Type 3c diabetes mellitus