title: Generation of Janus Molecularly Imprinted Polymer Particles.
abstract: Janus particles, which have two or more distinct physical surfaces, provide a number of potential applications in many fields. However, it is difficult to selectively load chemical or biological components onto the Janus particles. Here, the approach utilizing molecular imprinting and Pickering emulsion technologies for the synthesis of molecularly imprinted polymer (MIP)-based Janus particles (which showed high affinity to the targets) is described stepwise. As self-propelled microengines possessing specific molecular recognition ability, Janus molecularly imprinted polymer particles show high potential for specific and well-controlled drug delivery.
authors.affiliation: Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Hangkong Road #13, Wuhan, Hubei, 430030, China. xtshenlab@hust.edu.cn.
authors.forename: Xiantao
authors.initials: X
authors.lastname: Shen
authors.affiliation: School of Pharmacy, University of Oslo, 1068, Blindern, 0316, Oslo, Norway.
authors.forename: Chuixiu
authors.initials: C
authors.lastname: Huang
authors.affiliation: Division of Pure and Applied Biochemistry, Lund University, Lund, Sweden.
authors.forename: Lei
authors.initials: L
authors.lastname: Ye
mesh_terms: D003102:Colloids; D054802:Molecular Imprinting / Q000379:methods*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D003102:Colloids; D011108:Polymers
keywords: Colloidosomes; Drug delivery; Janus particles; Molecular imprinting; Pickering emulsion; Self-propelled microengine