title: Single-incision versus 3-port laparoscopic cholecystectomy in symptomatic gallstones: A prospective randomized study.
abstract: Laparoscopic cholecystectomy is the standard treatment for symptomatic gallbladder disease. Single-incision laparoscopic surgery was developed with the aim of decreasing the invasiveness of conventional laparoscopy. The aim of this study was to compare the clinical outcome of single-incision laparoscopic cholecystectomy with 3-port laparoscopic cholecystectomy.
  
  
  
  From February 2014 to September 2016, 187 patients with symptomatic cholecystolithiasis were randomized to a single-incision laparoscopic cholecystectomy group (89 patients) or a 3-port laparoscopic cholecystectomy group (98 patients). The primary outcomes were a postoperative pain score (at 6 hours and 1 day) and patients of complications, while the secondary outcomes were operative time, estimated blood loss, opioid requirements, duration of hospital stay, and patient satisfaction with aesthetic effects.
  
  
  
  When comparing 3-port laparoscopic cholecystectomy and single-incision laparoscopic cholecystectomy, there were differences in the (mean ± standard deviation) operative time (58.9 ± 18.6 minutes vs 45.2 ± 11.8 minutes; P < .001), success rate (93% vs 99%; P < .01), conversion rate (7% vs 1%; P < .001), and aesthetic score (7.9 ± 1.6 vs 6.7 ± 1.4; P = .008). There were no statistically significant differences in estimated blood loss, postoperative pain, opioid requirement, complications, and hospital stay between both groups.
  
  
  
  Single-incision laparoscopic cholecystectomy is a safe and feasible procedure in selected patients. The main advantage is the superior aesthetic results, while the main disadvantage is a greater operative time with some technical difficulties.
authors.affiliation: General Surgery Department, South Valley University, Qena, Egypt. Electronic address: mohamed_ali@med.svu.edu.eg.
authors.forename: Mohammed A
authors.initials: MA
authors.lastname: Omar
authors.affiliation: General Surgery Department, Sohag University, Sohag, Egypt.
authors.forename: Alaa A
authors.initials: AA
authors.lastname: Redwan
authors.affiliation: General Surgery Department, Sohag University, Sohag, Egypt.
authors.forename: Ahmed G
authors.initials: AG
authors.lastname: Mahmoud
mesh_terms: D000328:Adult; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects / Q000379:methods*; D005260:Female; D042882:Gallstones / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007431:Intraoperative Complications / Q000453:epidemiology* / Q000517:prevention & control; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D017060:Patient Satisfaction; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control; D011446:Prospective Studies; D016896:Treatment Outcome