title: Drug Interactions in the Treatment of Malignancy in HIV-Infected Patients.
abstract: The number of patients with HIV (human immunodeficiency virus) requiring treatment for malignancy is increasing worldwide. Concurrent treatment of HIV and malignancy is complicated by unpredictable drug-drug interactions, which can cause potentially life-threatening toxicities and ineffective treatment of either disease. This article aims to provide a practical approach to drug interactions and their management in this context to help deliver effective and safe treatment of both the malignancy and HIV.
authors.forename: Tanya
authors.initials: T
authors.lastname: Welz
authors.forename: Christoph
authors.initials: C
authors.lastname: Wyen
authors.forename: Manfred
authors.initials: M
authors.lastname: Hensel
mesh_terms: D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D004347:Drug Interactions; D004359:Drug Therapy, Combination / Q000009:adverse effects / Q000379:methods / Q000592:standards; D064420:Drug-Related Side Effects and Adverse Reactions / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D019317:Evidence-Based Medicine; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008495:Medical Oncology / Q000592:standards; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome
chemical_list: D019380:Anti-HIV Agents; D000970:Antineoplastic Agents