title: Extraneural Metastases From Desmoplastic Medulloblastoma Masquerading as Lymphoma.
abstract: Medulloblastoma is a WHO grade IV neoplasm that is usually restricted to the central nervous system, with metastasis occurring along the neuraxis through the ventricular system and cerebrospinal fluid. Extraneural metastasis is rare, usually occurs in bones/lymph nodes, and carries poor prognosis. We report multimodal imaging in a 14-year-old boy with desmoplastic medulloblastoma having multiple extraneural nodal and skeletal metastases, which was misdiagnosed as lymphoma. This case highlights the importance of understanding tumor biology with active clinical and radiological surveillance that is useful in early detection of extraneural metastasis of this aggressive tumor that helps in advocating appropriate and timely treatment.
authors.affiliation: From the Departments of *Radiodiagnosis, †Pathology, ‡Nuclear Medicine and Molecular Imaging, §Radiation Oncology, ∥Pediatric Oncology, and ¶Neurosurgery (Department of Surgical Oncology), Tata Memorial Hospital, Tata Memorial Centre, Mumbai, Maharashtra, India.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Mahajan
authors.forename: Peter
authors.initials: P
authors.lastname: Paul
authors.forename: Epari
authors.initials: E
authors.lastname: Sridhar
authors.forename: Venkatesh
authors.initials: V
authors.lastname: Rangarajan
authors.forename: Tejpal
authors.initials: T
authors.lastname: Gupta
authors.forename: Girish
authors.initials: G
authors.lastname: Chinnaswamy
authors.forename: Aliasgar
authors.initials: A
authors.lastname: Moiyadi
authors.forename: Rakesh
authors.initials: R
authors.lastname: Jalali
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D003937:Diagnosis, Differential; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008297:Male; D008527:Medulloblastoma / Q000000981:diagnostic imaging* / Q000473:pathology