title: Photoacoustic spectroscopy that uses a resonant characteristic of a microphone for in vitro measurements of glucose concentration.
abstract: Glucose measurements using photoacoustic spectroscopy have been highlighted to be a modality for non-invasive glucose monitoring. Previous photoacoustic spectroscopy for glucose measurements have used a resonant acoustic cell with a broadband capacitive microphone to increase sensitivity. However, a resonant characteristic of a microphone has not been investigated yet due to the working frequency range much lower than the resonance frequency of the microphone membrane. We, here, present a photoacoustic spectroscopy system that utilizes an ultrasound resonance of a microphone to increase sensitivity. We found that matching the resonance of a photoacoustic cell with the resonance of a microphone can increase signal-to-noise ratio and our system can distinguish the glucose concentration in liquid.
authors.lastname: Joo Yong Sim
authors.lastname: Chang-Geun Ahn
authors.lastname: Eunju Jeong
authors.lastname: Bong Kyu Kim
mesh_terms: D045604:Extracellular Fluid / Q000737:chemistry; D005947:Glucose / Q000032:analysis*; D016018:Least-Squares Analysis; D061088:Photoacoustic Techniques / Q000295:instrumentation*; D012044:Regression Analysis; D012815:Signal Processing, Computer-Assisted; D013057:Spectrum Analysis / Q000379:methods*
chemical_list: D005947:Glucose