title: May intraperitoneal irrigation with Betadine improve cesarean delivery outcomes? Results of a 6 years' single centre experience.
abstract: OBJECTIVE
  Cesarean presents increased risk of adverse outcomes, such as endometritis, bacteremia, peritonitis, and maternal fever. This retrospective study aims to evaluate, for the first time in Literature, the effects Betadine washing versus normal saline washing after uterine closure in women undergoing cesarean delivery (CD) at ≥36 gestational weeks.
  
  
  METHODS
  Of the 2080 patients identified retrospectively for the analysis at Department of Obstetrics and Gynecology of San Camillo Hospital of Rome, 1042 were assigned to "Betadine group" and 1038 to "No Betadine group". There were no differences noted for maternal and obstetric characteristics. The outcomes of the present study were to evaluate the incidence of postoperative infections or fever; the reduction of blood white cells among preoperative and postoperative exams; mean and median time of intestinal recanalization, of postoperative ambulation and of 24-h post-CD pain, evaluated using VAS scale.
  
  
  RESULTS
  Betadine group patients reported a statistically significant lower white cells increment, a lower mean time to ambulation and intestinal recanalization after CD and a lower 24-h post-CD pain and infections.
  
  
  CONCLUSIONS
  Betadine intraperitoneal irrigation during CD seems to improve postoperative CD outcomes and patients' quality of life.
authors.affiliation: a Department of Obstetrics & Gynecology, Division of Maternal Fetal Medicine , San Camillo-Forlanini Hospital , Rome , Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Marino
authors.affiliation: b Department of Obstetrics and Gynaecology Campus Bio-Medico , University of Rome , Rome , Italy.
authors.forename: Stella
authors.initials: S
authors.lastname: Capriglione
authors.affiliation: c Department of Biomedicine and Prevention, Section of Gynecology and Obstetrics , University of Rome Tor Vergata , Rome , Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Morosetti
authors.affiliation: c Department of Biomedicine and Prevention, Section of Gynecology and Obstetrics , University of Rome Tor Vergata , Rome , Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Di Angelo Antonio
authors.affiliation: b Department of Obstetrics and Gynaecology Campus Bio-Medico , University of Rome , Rome , Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Miranda
authors.affiliation: c Department of Biomedicine and Prevention, Section of Gynecology and Obstetrics , University of Rome Tor Vergata , Rome , Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Pazzola
authors.affiliation: b Department of Obstetrics and Gynaecology Campus Bio-Medico , University of Rome , Rome , Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Lopez
authors.affiliation: c Department of Biomedicine and Prevention, Section of Gynecology and Obstetrics , University of Rome Tor Vergata , Rome , Italy.
authors.forename: Lodovico
authors.initials: L
authors.lastname: Patrizi
authors.affiliation: b Department of Obstetrics and Gynaecology Campus Bio-Medico , University of Rome , Rome , Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Angioli
authors.affiliation: a Department of Obstetrics & Gynecology, Division of Maternal Fetal Medicine , San Camillo-Forlanini Hospital , Rome , Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Stella
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000627:therapeutic use; D002585:Cesarean Section / Q000379:methods*; D005260:Female; D006801:Humans; D015994:Incidence; D010533:Peritoneal Lavage / Q000379:methods*; D011206:Povidone-Iodine / Q000008:administration & dosage* / Q000627:therapeutic use; D011247:Pregnancy; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine
keywords: Betadine; Betadine washing; Cesarean delivery; postoperative outcomes