title: A new diterpenoid alkaloid isolated from Delphinium caeruleum.
abstract: The present study was designed to determine the chemical constituents of Delphinium caeruleum Jacq. ex Camb.. The chemical constituents were isolated and purified by column chromatography with silica gel, ODS, and Sephadex LH-20. Their structures were elucidated by IR, MS, and NMR. Ten compounds were obtained and identified as caerudelphinine A (1), lycoctonine (2), talitine B (3), talitine A (4), talitine C (5), tatsienine-V (6), d-magnoflorine (7), 2-trimethyl-ammonio-3-(3-indolyl) propionate (8), vakhmatine (9), and delatisine (10). Compound 1 was a new lycoctonine-type C19-diterpenoid alkaloid, and compounds 4-10 were isolated from this plant for the first time.
authors.affiliation: Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
authors.forename: Chao-Zhan
authors.initials: CZ
authors.lastname: Lin
authors.affiliation: Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
authors.forename: Zhu-Jie
authors.initials: ZJ
authors.lastname: Liu
authors.affiliation: Tibetan Traditional Medical College, Lasa 850000, China.
authors.forename: Zeren-Dawa
authors.initials: ZD
authors.lastname: Bairi
authors.affiliation: Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou 510405, China. Electronic address: zhuchenchen@vip.sina.com.
authors.forename: Chen-Chen
authors.initials: CC
authors.lastname: Zhu
mesh_terms: D000157:Aconitine / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D001060:Aporphines / Q000737:chemistry / Q000302:isolation & purification; D031882:Delphinium / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D001060:Aporphines; D004224:Diterpenes; D010936:Plant Extracts; C000615913:caerudelphinine A; C093992:lycoctonine; C067313:tatsiensine; C001670:magnoflorine; D000157:Aconitine
keywords: Alkaloids; Caerudelphinine A; Delphinium caeruleum