title: Lymphocytic Meningitis in Patients with Sympathetic Ophthalmia.
abstract: OBJECTIVE
  This study aimed at reporting lymphocytic meningitis in patients diagnosed with sympathetic ophthalmia (SO).
  
  
  METHODS
  In this single-center retrospective observational case series, we reviewed cases diagnosed with SO. We analyzed the patients' inciting injuries, the characteristics of uveitis and the cerebrospinal fluid (CSF) analyses.
  
  
  RESULTS
  Nine patients were diagnosed with SO and CSF analyses were available in all cases. Four cases had lymphocytic pleocytosis, 3 of which showed marked CSF inflammation with more than 300 lymphocytes/mm3. The inciting event in these 3 patients was a globe perforation injury, whereas 4 patients without meningitis had SO following a surgical intervention.
  
  
  CONCLUSIONS
  In this case series of patients with SO, lymphocytic meningitis was a common finding. The prevalence of meningitis in patients with SO and its value for the diagnosis of the disease needs to be further studied.
authors.affiliation: a Department of Ophthalmology , Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
authors.forename: Mathilde
authors.initials: M
authors.lastname: Goudot
authors.affiliation: b Department of Internal Medicine , National Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
authors.forename: Matthieu
authors.initials: M
authors.lastname: Groh
authors.affiliation: a Department of Ophthalmology , Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
authors.forename: Sawsen
authors.initials: S
authors.lastname: Salah
authors.affiliation: a Department of Ophthalmology , Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Monnet
authors.affiliation: b Department of Internal Medicine , National Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Blanche
authors.affiliation: a Department of Ophthalmology , Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
authors.forename: Antoine P
authors.initials: AP
authors.lastname: Brézin
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007964:Leukocytosis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D008875:Middle Aged; D009879:Ophthalmia, Sympathetic / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D015995:Prevalence; D012189:Retrospective Studies; D013129:Spinal Puncture; D055815:Young Adult
keywords: Cerebrospinal fluid pleocytosis; lumbar puncture; meningitis; panuveitis; sympathetic ophthalmia