abstract: Pyoderma gangrenosum belongs to the chronic, neutrophilic and necrotic dermatoses. These very painful, inflammable and purulent skin-ulcers often arise after injury or surgical intervention. About half of the patients suffer from systemic disease, for example hematological, gastrointestinal or rheumatic diseases.Our report includes a 77-year-old female with a multilocular emergence of pyoderma gangrenosum following surgery for an orbital pseudotumor.An additional lesion was detected on her anterior neck. Because the possibility of wound-infection was suspected, the lesion was treated locally and with a systemic antibiotic therapy. After this treatment, the condition of the wound deteriorated. Upon dermatological examination, pyoderma gangrenosum was identified and a immunosuppressive therapy with corticosteroids and cyclosporin was initiated. As a result of this treatment, the lesion healed slowly - with the formation of typical, atrophic and reticular scars.A connection between the pyoderma gangrenosum and the orbital pseudotumor can, on the basis of similar clinical and structural characteristics, not be excluded. A related disease was not diagnosed in this patient. Recurrence can be predicted in patients who have had skin injuries, therefore strict observation is required.
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie der Martin-Luther-Universität Halle-Wittenberg.|HNO-Klinik der Martin-Luther-Universität Halle-Wittenberg, Magdeburger Straße 12, 06097 Halle/S.
authors.forename: C
authors.initials: C
authors.lastname: Welzel
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie der Martin-Luther-Universität Halle-Wittenberg.
authors.forename: M
authors.initials: M
authors.lastname: Bloching
authors.affiliation: Klinik und Poliklinik für Dermatologie und Venerologie der Martin-Luther-Universität Halle-Wittenberg.
authors.forename: S
authors.initials: S
authors.lastname: Born
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie der Martin-Luther-Universität Halle-Wittenberg.
authors.forename: A
authors.initials: A
authors.lastname: Berghaus
keywords: Associated diseases; Chronic behaviour; Immunosuppressive therapy; Orbital pseudotumor; Postoperative; Pyoderma gangrenosum