title: Merging N-Heterocyclic Carbene Catalysis and Single Electron Transfer: A New Strategy for Asymmetric Transformations.
abstract: Radical chemistry meets NHCs: NHC catalysis and single electron oxidants have been merged in several transformations, allowing the synthesis of useful β-hydroxy esters, cyclopentanones, and spirocyclic γ-lactones in a highly stereoselective manner. The key step is the oxidation of the NHC homoenolate equivalent to a radical species via a single-electron transfer process.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Kun
authors.initials: K
authors.lastname: Zhao
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Dieter
authors.initials: D
authors.lastname: Enders
keywords: N-heterocyclic carbenes; asymmetric catalysis; organocatalysis; radicals; single electron transfer