title: Microbes and Diet-Induced Obesity: Fast, Cheap, and Out of Control.
abstract: Here I revisit our early experiments published in Cell Host & Microbe (Turnbaugh et al., 2008) showing that a diet rich in fat and simple sugars alters the gut microbiome in a manner that contributes to host adiposity, and reflect upon the remarkable advances and remaining challenges in this field.
authors.affiliation: Department of Microbiology and Immunology, G.W. Hooper Research Foundation, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address: peter.turnbaugh@ucsf.edu.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Turnbaugh
mesh_terms: D000818:Animals; D003600:Cytosol / Q000737:chemistry; D004032:Diet / Q000009:adverse effects* / Q000379:methods*; D000069196:Gastrointestinal Microbiome / Q000187:drug effects*; D006801:Humans; D009765:Obesity
keywords: cellular memory; diet-induced obesity; gut microbiome; high-fat and high-sugar diets; metabolic disease; metagenomics; metatranscriptomics; microbial dynamics; multi-omics; nutrition