title: [Newborn outcomes after radiofrequency ablation for selective reduction in the complicated monochorionic pregnancies].
abstract: OBJECTIVE
  To describe perinatal data and to evaluate the neonatal neurological outcome of monochorionic twin pregnancies with selective termination by radiofrequency ablation.
  
  
  METHODS
  Retrospective data of perinatal data for nine consecutive monochorionic pregnancies eligible for radiofrequency ablation from January 2013 to August 2015 were collected. A prospective observational study of the neurological outcome of nine children was conducted using the Ages & Stages Questionnaire (ASQ), 2nd edition, French version, adapted to the age.
  
  
  RESULTS
  The radiofrequency procedures were performed at a mean gestational age (GA) of 21.4 weeks (±7 weeks). The indications for a selective interruption of a pregnancy were: acardiac twin (n=4), brain malformation (n=1), severe intrauterine growth restriction (IUGR) with massive cerebral ischemia in the context of twin-twin transfusion syndrome grade III (n=1), severe selective IUGR associated with a polymalformative syndrome (n=1) and severe selective IUGR (n=2). The mean GA at birth was 36.7 weeks GA (±3.8 weeks). No infant showed neurological neonatal morbidity. Any ASQ area explored was pathological (<-2SD) for the nine children (mean age at follow-up [±SD], 14.8 months [±8.8 months]).
  
  
  CONCLUSIONS
  This work constitutes a preliminary study for developing long-term follow-up and early care programs for those children born subsequent to a radiofrequency ablation for selective reduction.
authors.affiliation: Service de néonatologie et soins intensifs, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université, chemin des Bourrely, 13015 Marseille, France.
authors.forename: M
authors.initials: M
authors.lastname: Panciatici
authors.affiliation: Service de néonatologie et soins intensifs, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université, chemin des Bourrely, 13015 Marseille, France. Electronic address: barthelemy.tosello@ap-hm.fr.
authors.forename: B
authors.initials: B
authors.lastname: Tosello
authors.affiliation: Service de gynécologie obstétrique, centre pluridisciplinaire de diagnostic prénatal, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université, 13015 Marseille, France.
authors.forename: J
authors.initials: J
authors.lastname: Blanc
authors.affiliation: Service de gynécologie obstétrique, hôpital Saint-Joseph, 13285 Marseille, France.
authors.forename: J-B
authors.initials: JB
authors.lastname: Haumonté
authors.affiliation: Service de gynécologie obstétrique, centre pluridisciplinaire de diagnostic prénatal, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université, 13015 Marseille, France.
authors.forename: C
authors.initials: C
authors.lastname: D'Ercole
authors.affiliation: Service de néonatologie et soins intensifs, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université, chemin des Bourrely, 13015 Marseille, France.
authors.forename: C
authors.initials: C
authors.lastname: Gire
mesh_terms: D055011:Ablation Techniques / Q000009:adverse effects / Q000379:methods*; D000013:Congenital Abnormalities; D004200:Diseases in Twins; D005260:Female; D005317:Fetal Growth Retardation; D005330:Fetofetal Transfusion; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011256:Pregnancy Outcome; D018607:Pregnancy Reduction, Multifetal / Q000379:methods*; D059285:Pregnancy, Twin; D012189:Retrospective Studies; D014430:Twins, Monozygotic
keywords: ASQ; Ablation par radiofréquence; Devenir neurologique; Fœticide sélectif; Grossesses monochoriales; Monochorionic pregnancies; Neurological outcome; Radiofrequency ablation; Selective foeticide