title: Medication Adherence Mediates the Association between Type D Personality and High HbA1c Level in Chinese Patients with Type 2 Diabetes Mellitus: A Six-Month Follow-Up Study.
abstract: Aims. To examine the association between Type D personality and HbA1c level and to explore the mediating role of medication adherence between them in patients with type 2 diabetes mellitus (T2DM).Methods. 330 patients went on to complete a self-report measure of medication adherence and the HbA1c tests. Chi-square test,Ttest, Ordinary Least Square Regression (OLS), and Recentered Influence Function Regression (RIF) were employed.Results. Patients with Type D personality had significantly higher HbA1c value (P< 0.01). When Type D personality was operationalized as a categorical variable, SI was associated with HbA1c (P< 0.01). When NA, SI, and their interaction term were entered into regression, all of them were no longer associated with HbA1c level (P> 0.1). On the other hand, when Type D personality was operationalized as a continuous variable, only SI trait was associated with HbA1c level (P< 0.01). When NA, SI, and NA × SI term together were entered into regression, only SI was not related to HbA1c level. Furthermore, medication adherence had a significant mediation effect between Type D personality and HbA1c, accounting for 54.43% of the total effect.Conclusion. Type D personality was associated with HbA1c in direct and indirect ways, and medication adherence acted as a mediator role.
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China; Clinics of Cadre, Department of Outpatient, General Hospital of the People's Liberation Army (301 Hospital), Beijing 100853, China.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Li
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
authors.forename: Min
authors.initials: M
authors.lastname: Gao
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
authors.forename: Shengfa
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Public Health Sciences, University of Rochester School of Medicine & Dentistry, Rochester, NY 14642, USA.
authors.forename: Huiwen
authors.initials: H
authors.lastname: Xu
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
authors.forename: Huixuan
authors.initials: H
authors.lastname: Zhou
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Wang
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Qu
authors.affiliation: Department of Sociology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Guo
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
authors.forename: Weijun
authors.identifier: 0000-0003-3436-3371
authors.initials: W
authors.lastname: Zhang
authors.affiliation: School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
authors.forename: Donghua
authors.identifier: 0000-0003-4586-5502
authors.initials: D
authors.lastname: Tian
mesh_terms: D002681:China; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D064415:Type D Personality
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human