title: Characterization of cardiac- and respiratory-driven cerebrospinal fluid motions using correlation mapping with asynchronous 2-dimensional phase contrast technique.
abstract: To investigate spatial distribution properties of the cardiac- and respiratory-driven cerebrospinal fluid (CSF) motions in the intracranial space, correlation mapping technique was conducted. Time series of CSF velocity were acquired in 7 healthy subjects of 26±5 years old under by asynchronous 2-dimensional phase contrast (2D-PC) method with 217-msec temporal resolution. The delay time and maximum correlation maps of the cardiac- and respiratory-driven CSF motions demonstrated clear differences in the propagation properties. When the reference region was set at anterior spinal subarachnoid space, the maximum correlation coefficients in the case of 6-sec respiratory period were 0.91±0.05 for cardiac-driven and 0.78±0.08 for respiratory-driven. They were 0.90±0.06 and 0.81±0.06 in the case of 10-sec period. The cardiac- and respiratory CSF motions differently distributed in intracranial space.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yatsushiro
authors.forename: Saeko
authors.initials: S
authors.lastname: Sunohara
authors.forename: Ken
authors.initials: K
authors.lastname: Takizawa
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Matsumae
authors.forename: Nao
authors.initials: N
authors.lastname: Kajihara
authors.forename: Kagayaki
authors.initials: K
authors.lastname: Kuroda
mesh_terms: D000328:Adult; D002555:Cerebrospinal Fluid / Q000502:physiology*; D005260:Female; D005583:Fourier Analysis; D064368:Healthy Volunteers; D006321:Heart; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009038:Motion; D012119:Respiration; D013346:Subarachnoid Space