title: The evaluation of renal parenchymal scarring using static renal scintigraphy after percutaneous nephrolithotomy operations.
abstract: To analyze whether operative techniques and other variables related to patient and renal stone characteristics affect potential renal parenchymal damage.
  
  
  
  The study population comprised 64 patients who underwent percutaneous nephrolithotomy operations (PCNL). Data of the operated renal units, renal stone burden, route and number of entries, dilation techniques, duration of surgery, preoperative and postoperative glomerular filtration rate (GFR) and relative dimercaptosuccinic acid (DMSA) uptakes, as well as the changes in hemoglobin values, were recorded and analyzed for all patients.
  
  
  
  The mean age of the patients was 44 years. In 11 (17.1%) cases, renal cortical defects in the 3rd month were detected on DMSA scintigraphy. When the patients with and without renal cortical defect were compared regarding their preoperative and postoperative GFR values, no statistically significant difference was noticed between the groups (P > 0.05). Similarly, when postoperative relative DMSA uptakes were compared with preoperative relative DMSA uptakes of the same kidneys, no statistical significance was seen. When preoperative relative DMSA uptake values between groups with and without renal scarring were compared, no statistically significant difference was observed (P > 0.05).
  
  
  
  We did not observe any significant difference in scintigraphic parameters and GFR values. Hence, in the current trial, significant loss in renal function after PCNL operations was not observed. Thus, PCNL operations should be regarded as safe, but still, the risk of loss of kidney function should always be considered.
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Yalcinkaya
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Ates
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Yuksel
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Islamoglu
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Tokgoz
authors.affiliation: Department of Nephrology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.
authors.forename: E U
authors.initials: EU
authors.lastname: Ates
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Yildız
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Yilmaz
authors.affiliation: Department of Urology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Savas
mesh_terms: D000328:Adult; D000368:Aged; D002921:Cicatrix / Q000000981:diagnostic imaging* / Q000209:etiology*; D005260:Female; D005919:Glomerular Filtration Rate; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007669:Kidney Calculi / Q000503:physiopathology / Q000601:surgery*; D007672:Kidney Cortex / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D000074642:Nephrolithotomy, Percutaneous / Q000009:adverse effects*; D011184:Postoperative Period; D057234:Preoperative Period; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D055815:Young Adult
chemical_list: D006454:Hemoglobins; D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid