title: Investigation of driving forces of cerebrospinal fluid motion by power and frequency mapping based on asynchronous phase contrast technique.
abstract: To classify the cardiac- and respiratory-driven cerebrospinal fluid (CSF) motions, asynchronous 2D phase contrast (PC) of magnetic resonance imaging (MRI) with 217 ms time resolution in conjunction with power and frequency mapping was performed for 7 healthy subjects under respiration guidance. In the frequency domain, the cardiac-driven motion was at around 1.29±0.21 Hz and respiratory-driven motion was at 0.16±0.01 Hz under 6 sec respiratory cycle. Two different techniques were proposed for characterizing the motions; one was power-map (P-map) depicting integrated power spectrum in a selected band, and the other was frequency-map (F-map) delineating the frequency of maximum peak in power spectral density (PSD). These maps visualized the anatomical distributions of the two motions. Portions of the cardiac- and respiratory-driven CSF motions in the spinal subarachnoid space were 58.1±22.2 and 9.50±3.83 %, respectively. Power and frequency mapping clearly classified the cardiac-driven and respiratory-driven CSF motions.
authors.forename: Saeko
authors.initials: S
authors.lastname: Sunohara
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yatsushiro
authors.forename: Ken
authors.initials: K
authors.lastname: Takizawa
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Matsumae
authors.forename: Nao
authors.initials: N
authors.lastname: Kajihara
authors.forename: Kagayaki
authors.initials: K
authors.lastname: Kuroda
mesh_terms: D002555:Cerebrospinal Fluid / Q000000981:diagnostic imaging*; D006321:Heart; D006801:Humans; D008279:Magnetic Resonance Imaging; D008858:Microscopy, Phase-Contrast; D009068:Movement; D012119:Respiration