title: Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy.
abstract: OBJECTIVE
  To evaluate outcomes in pediatric patients undergoing lensectomy, posterior capsulotomy, and triamcinolone-assisted vitrectomy for congenital cataract.
  
  
  METHODS
  This retrospective study included 34 patients younger than 72 months who underwent lensectomy, posterior capsulotomy, and triamcinolone-assisted vitrectomy with or without intraocular lens (IOL) implantation for cataract at the National Taiwan University Hospital from July 2006 to December 2012.
  
  
  RESULTS
  Fifty-one eyes from 34 patients with cataract (unilateral in 17 patients, bilateral in 17 patients) were included. The mean age at surgery was 26.74 months (range: 2-72 months). The mean postoperative follow-up was 27.8 months (range: 6-72 months). Primary IOL implantation was performed in 25 eyes, 21 of which had the IOL implanted in the capsular bag. Fifty eyes had a central round pupil. The median logarithm of the minimum angle of resolution visual acuity was 0.3 in patients with unilateral cataract and 0.1 in those with bilateral cataract. Three eyes (5.9%) developed visual axis opacification (VAO) and required further surgery. Univariate analysis using Fisher's exact test indicated that surgery in the first 12 months of life was significantly associated with development of VAO (p=0.047). The incidence of postoperative VAO was approximately 15.8% in this age group.
  
  
  CONCLUSIONS
  Triamcinolone-assisted vitrectomy can be used in pediatric cataract surgery without serious long-term adverse effects. While the incidence of VAO is low, it appears unavoidable in approximately one-sixth of patients who undergo surgery before 12 months of age.
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China.
authors.forename: Tzu-Hsun
authors.initials: TH
authors.lastname: Tsai
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
authors.forename: Chia-Ying
authors.initials: CY
authors.lastname: Tsai
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; Department of Ophthalmology, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China.
authors.forename: Jehn-Yu
authors.initials: JY
authors.lastname: Huang
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; Department of Ophthalmology, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China. Electronic address: fungronghu@ntu.edu.tw.
authors.forename: Fung-Rong
authors.initials: FR
authors.lastname: Hu
mesh_terms: D002386:Cataract / Q000151:congenital*; D002387:Cataract Extraction / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D007910:Lenses, Intraocular; D008297:Male; D012189:Retrospective Studies; D013624:Taiwan; D014221:Triamcinolone / Q000008:administration & dosage; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*
chemical_list: D005938:Glucocorticoids; D014221:Triamcinolone
keywords: anterior vitrectomy; pediatric cataract; triamcinolone acetonide