title: Transition-Metal-Catalyzed Utilization of Methanol as a C1Source in Organic Synthesis.
abstract: Methanol is used as a common solvent, cost-effective reagent, and sustainable feedstock for value-added chemicals, pharmaceuticals, and materials. Among the various applications, the utilization of methanol as a C1source for the formation of carbon-carbon, carbon-nitrogen, and carbon-oxygen bonds continues to be important in organic synthesis and drug discovery. In particular, the synthesis of C-, N-, and O-methylated products is of central interest because these motifs are found in a large number of natural products as well as fine and bulk chemicals. In this Minireview, we summarize the utilization of methanol as a C1source in methylation, methoxylation, formylation, methoxycarbonylation, and oxidative methyl ester formation reactions.
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, LIKAT Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Kishore
authors.initials: K
authors.lastname: Natte
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, LIKAT Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Helfried
authors.initials: H
authors.lastname: Neumann
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, LIKAT Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, LIKAT Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Rajenahally V
authors.initials: RV
authors.lastname: Jagadeesh
keywords: esterification; formylation; methanol; methoxylation; methylation