title: Cardiac Involvement Classification and Therapeutic Management in Patients with Duchenne Muscular Dystrophy.
abstract: Duchenne muscular dystrophy (DMD) is an inherited myogenic disorder due to mutations in the dystrophin gene on chromosome Xp21.1. The clinical picture included peripheral muscle weakness, cardiomyopathy and chronic respiratory insufficiency. In this paper, the authors review cardiac involvement in patients with DMD, propose a cardiac impairment classification and discuss therapeutic management options.
authors.affiliation: APHP, Raymond Poincare Hospital, University of Versailles, Garches, France.|Myology Institute, Pitié Salpetrière Hospital, Paris, France.
authors.forename: Abdallah
authors.initials: A
authors.lastname: Fayssoil
authors.affiliation: Pediatric Center, Mayotte Hospital Center, Mayotte, Island.
authors.forename: Soumeth
authors.initials: S
authors.lastname: Abasse
authors.affiliation: APHP, Beaujon Hospital, Emergency department, Paris, France.
authors.forename: Katy
authors.initials: K
authors.lastname: Silverston
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000145:classification / Q000503:physiopathology* / Q000628:therapy; D058406:Cardiac Resynchronization Therapy; D009202:Cardiomyopathies / Q000145:classification / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy; D004232:Diuretics / Q000627:therapeutic use; D016189:Dystrophin; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D006801:Humans; D008279:Magnetic Resonance Imaging; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use; D020388:Muscular Dystrophy, Duchenne / Q000503:physiopathology*
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D004232:Diuretics; D016189:Dystrophin; D000451:Mineralocorticoid Receptor Antagonists
keywords: CMR; Duchenne muscular dystrophy; cardiomyopathy; classification; echocardiography