title: International kidney paired donation transplantations to increase kidney transplant of O group and highly sensitized patient: First report from India.
abstract: OBJECTIVE
  To report the first international living related two way kidney paired donation (KPD) transplantation from India which occurred on 17thFebruary 2015 after legal permission from authorization committee.
  
  
  METHODS
  Donor recipient pairs were from Portugal and India who were highly sensitized and ABO incompatible with their spouse respectively. The two donor recipient pairs had negative lymphocyte cross-matching, flow cross-match and donor specific antibody in two way kidney exchange with the intended KPD donor. Local KPD options were fully explored for Indian patient prior to embarking on international KPD.
  
  
  RESULTS
  Both pairs underwent simultaneous uneventful kidney transplant surgeries and creatinine was 1 mg/dL on tacrolimus based immunosuppression at 11 mo follow up. The uniqueness of these transplantations was that they are first international KPD transplantations in our center.
  
  
  CONCLUSIONS
  International KPD will increases quality and quantity of living donor kidney transplantation. This could be an important step to solving the kidney shortage with additional benefit of reduced costs, improved quality and increased access for difficult to match incompatible pairs like O blood group patient with non-O donor and sensitized patient. To the best of our knowledge this is first international KPD transplantation from India.
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Vivek B
authors.initials: VB
authors.lastname: Kute
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Himanshu V
authors.initials: HV
authors.lastname: Patel
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Pankaj R
authors.initials: PR
authors.lastname: Shah
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Pranjal R
authors.initials: PR
authors.lastname: Modi
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Veena R
authors.initials: VR
authors.lastname: Shah
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Sayyed J
authors.initials: SJ
authors.lastname: Rizvi
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Bipin C
authors.initials: BC
authors.lastname: Pal
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Priya S
authors.initials: PS
authors.lastname: Shah
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Pavan S
authors.initials: PS
authors.lastname: Wakhare
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Saiprasad G
authors.initials: SG
authors.lastname: Shinde
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Vijay A
authors.initials: VA
authors.lastname: Ghodela
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Umesh T
authors.initials: UT
authors.lastname: Varyani
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Minaxi H
authors.initials: MH
authors.lastname: Patel
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Varsha B
authors.initials: VB
authors.lastname: Trivedi
authors.affiliation: Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Priya S Shah, Pavan S Wakhare, Saiprasad G Shinde, Vijay A Ghodela, Umesh T Varyani, Hargovind L Trivedi, Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Ahmedabad 380016, India.
authors.forename: Hargovind L
authors.initials: HL
authors.lastname: Trivedi
keywords: International kidney paired donation; Kidney paired donation; Living donor kidney transplantation