title: Ruticarpsides A-C, three new ester glycosides from the fruits of Tetradium ruticarpum.
abstract: In the course of our ongoing phytochemical investigation on the n-butanol extract of the fruits of Tetradium ruticarpum (Rutaceae), three new compounds, ruticarpsides A-C (1-3), were obtained and their structures were elucidated by a comprehensive analysis of NMR and MS data. Compound 3 showed a weak inhibition effect on nitric oxide production in BV-2 microglial cells stimulated with lipopolysaccharide.
authors.affiliation: a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences , Peking University Health Science Center , Beijing 100191 , China.
authors.forename: Wei
authors.initials: W
authors.lastname: He
authors.affiliation: a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences , Peking University Health Science Center , Beijing 100191 , China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences , Peking University Health Science Center , Beijing 100191 , China.
authors.forename: Ming-Bo
authors.initials: MB
authors.lastname: Zhao
authors.affiliation: a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences , Peking University Health Science Center , Beijing 100191 , China.
authors.forename: Ke-Wu
authors.initials: KW
authors.lastname: Zeng
authors.affiliation: a State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences , Peking University Health Science Center , Beijing 100191 , China.
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Tu
mesh_terms: D000818:Animals; D032086:Evodia; D005638:Fruit / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D017628:Microglia / Q000187:drug effects; D015394:Molecular Structure; D009569:Nitric Oxide / Q000096:biosynthesis; D027821:Rutaceae / Q000737:chemistry
chemical_list: D006027:Glycosides; D008070:Lipopolysaccharides; C000621560:ruticarpside C; D009569:Nitric Oxide
keywords: NO inhibition; Tetradium ruticarpum; ruticarpsides A–C