title: Noninvasive ECG imaging (ECGI): Mapping the arrhythmic substrate of the human heart.
abstract: This short communication accompanies my presentation at the International Congress on Sudden Cardiac Death held in Prague, March 30-April 1, 2017. It summarizes briefly studies of the cardiac electrophysiological substrate in patients with hereditary arrhythmogenic syndromes - the Long QT and Brugada syndromes - conducted noninvasively, in situ, using Electrocardiographic Imaging (ECGI). The same noninvasive approach was used to map the electrophysiological substrate of a post-infarction myocardial scar and to relate this substrate to the pattern of activation during reentrant ventricular tachycardia. My thoughts about a potential role for ECGI in cardiac research and clinical care are also expressed briefly, with examples from on-going work in my laboratory.
authors.affiliation: Washington University, St. Louis, USA. Electronic address: rudy@wustl.edu.
authors.forename: Yoram
authors.initials: Y
authors.lastname: Rudy
mesh_terms: D001145:Arrhythmias, Cardiac / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D018780:Body Surface Potential Mapping / Q000379:methods*; D053840:Brugada Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology; D004562:Electrocardiography / Q000379:methods; D006801:Humans; D008133:Long QT Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*