title: A systematic review of imaging anatomy in predicting functional significance of coronary stenoses determined by fractional flow reserve.
abstract: Fractional flow reserve (FFR) is the current gold standard to assess the physiological significance of coronary stenoses. With the development of coronary imaging techniques, several anatomic parameters have been investigated in vivo and their associations with FFR have been studied. The aim of this review is to summarize the accuracy of anatomic parameters derived by the present coronary imaging techniques including invasive coronary angiography, coronary computed tomography angiography, intravascular ultrasound and optical coherence tomography, in predicting a significant FFR. The impact of patient characteristics, lesion locations, variability of FFR and imaging resolution on the predictive ability are discussed.
authors.affiliation: Biomedical Instrument Institute, School of Biomedical Engineering, Med-X Research Institute, Shanghai Jiao Tong University, No. 1954, Hua Shan Road, Shanghai, 200030, China.
authors.forename: Miao
authors.initials: M
authors.lastname: Chu
authors.affiliation: Cardiovascular Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Neng
authors.initials: N
authors.lastname: Dai
authors.affiliation: The 3rd Division of Cardiology, Department of Cardiology, Guangdong General Hospital, Guangdong Provincial Cardiovascular Institute, Guangdong Academy of Medical Sciences, No.106, 2nd Zhongshan Road, Yuexiu district, Guangzhou, Guangdong, 510080, China. whyn2000@163.com.
authors.forename: Junqing
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Aarhus University Hospital, Skejby, Denmark.
authors.forename: Jelmer
authors.initials: J
authors.lastname: Westra
authors.affiliation: Biomedical Instrument Institute, School of Biomedical Engineering, Med-X Research Institute, Shanghai Jiao Tong University, No. 1954, Hua Shan Road, Shanghai, 200030, China. sxtu@sjtu.edu.cn.
authors.forename: Shengxian
authors.initials: S
authors.lastname: Tu
mesh_terms: D001783:Blood Flow Velocity; D057791:Cardiac Imaging Techniques; D000072226:Computed Tomography Angiography; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000503:physiopathology; D053805:Fractional Flow Reserve, Myocardial; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence; D018084:Ultrasonography, Interventional
keywords: Coronary computed tomography angiography; Fractional flow reserve; Intravascular ultrasound; Invasive coronary angiography; Optical coherence tomography