title: Demodex and rosacea revisited.
abstract: Demodex mites are part of the vast microbiome living on and within human skin. The interaction of the various microorganisms with the skin plays a key role in the maintenance of homeostasis. The precise role and function of Demodex mites within normal and diseased human skin remains elusive. The emergence of ivermectin as a key therapy for rosacea has refocused interest in the role of Demodex mites in the pathogenesis of this skin disease and the ability of Demodex to modulate the host immune system.
authors.affiliation: Education and Research Centre, St. Vincent's University Hospital, Dublin, Ireland.
authors.forename: Ellen M
authors.initials: EM
authors.lastname: Moran
authors.affiliation: The Charles Institute of Dermatology, University College Dublin, Dublin, Ireland.
authors.forename: Ruth
authors.initials: R
authors.lastname: Foley
authors.affiliation: The Charles Institute of Dermatology, University College Dublin, Dublin, Ireland. Electronic address: frank.powell@ucd.ie.
authors.forename: Frank C
authors.initials: FC
authors.lastname: Powell
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D008925:Mites / Q000502:physiology*; D012393:Rosacea / Q000188:drug therapy* / Q000469:parasitology*; D012867:Skin / Q000469:parasitology
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin