title: Dispelling misconceptions in the management of familial adenomatous polyposis.
abstract: Patients with familial adenomatous polyposis require surgical intervention at some point in their lives. The diagnosis is often apparent from their phenotype and family history, however, this is not always the case. Many factors can influence the surgical strategy although the polyposis burden and distribution remain the main consideration. While prophylactic removal of the rectum and colon is often required, sparing the rectum at the index surgery is safe in select patients. This article aims to dispel misconceptions in the diagnosis and treatment of patients with familial adenomatous polyposis.
authors.affiliation: Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.|Department of Surgery, The University of Melbourne, Melbourne, Victoria, Australia.
authors.forename: Timothy J
authors.identifier: http://orcid.org/0000-0003-2514-4230
authors.initials: TJ
authors.lastname: Chittleborough
authors.affiliation: Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.|Department of Colorectal Surgery, Alfred Health, Melbourne, Victoria, Australia.
authors.forename: Satish K
authors.initials: SK
authors.lastname: Warrier
authors.affiliation: Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.|Department of Surgery, The University of Melbourne, Melbourne, Victoria, Australia.
authors.forename: Alexander G
authors.initials: AG
authors.lastname: Heriot
authors.affiliation: Department of Colorectal Surgery, Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA.|Sanford R. Weiss, MD Center for Hereditary Colorectal Neoplasia, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Kalady
authors.affiliation: Department of Colorectal Surgery, Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA.|Sanford R. Weiss, MD Center for Hereditary Colorectal Neoplasia, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: James
authors.initials: J
authors.lastname: Church
mesh_terms: D000008:Abdominal Neoplasms / Q000150:complications* / Q000175:diagnosis; D011125:Adenomatous Polyposis Coli / Q000150:complications / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D000328:Adult; D000714:Anastomosis, Surgical / Q000592:standards; D000066491:Clinical Decision-Making; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D017281:Cost of Illness; D005260:Female; D018222:Desmoid Tumors / Q000150:complications* / Q000175:diagnosis; D005838:Genotype; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D008297:Male; D016737:Proctocolectomy, Restorative / Q000009:adverse effects / Q000379:methods*; D065286:Prophylactic Surgical Procedures / Q000941:ethics; D011788:Quality of Life; D012007:Rectum / Q000601:surgery; D012307:Risk Factors; D055990:Therapeutic Misconception / Q000941:ethics*
keywords: colorectal surgery; familial adenomatous polyposis; total proctocolectomy