title: On comparing in vivo intracranial recordings in non-human primates to predictions of optimized transcranial electrical stimulation.
abstract: Transcranial electrical stimulation (tES) can be optimized to achieve maximal current flow at desired brain regions. The aim of this study was to characterize electric field magnitudes generated by tES optimization and to compare them to experimentally induced values as determined by data from intracranial electrodes. Local field potentials were recorded from two monkeys with implanted multi-site intracranial Utah arrays during transcranial direct current stimulation (tDCS), and the neural effect predictions obtained from optimized electrode placement were assessed. Comparative data between the two sites of intracranial recordings during tDCS partially validated the predictions of our tES optimization algorithms.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Datta
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Krause
authors.forename: Praveen K
authors.initials: PK
authors.lastname: Pilly
authors.forename: Jaehoon
authors.initials: J
authors.lastname: Choe
authors.forename: Theodoras P
authors.initials: TP
authors.lastname: Zanos
authors.forename: Chris
authors.initials: C
authors.lastname: Thomas
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Pack
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D004558:Electric Stimulation; D004566:Electrodes; D011323:Primates; D065908:Transcranial Direct Current Stimulation; D014589:Utah