title: [Clinical features of «metabolism» diseases of the skin in patients with chronic diffuse liver diseases].
abstract: OBJECTIVE
  To determine the clinical features of skin diseases developing in the presence of metabolic disturbances in patients with chronic diffuse liver diseases.
  
  
  METHODS
  A total of 368 patients with different clinical forms of hepatopathy were comprehensively examined.
  
  
  RESULTS
  817 cases of seborrhea, skin itch, xerodermia, xanthomatosis, and dyschromia were detected in 318 (86.4%) patients.
  
  
  CONCLUSIONS
  The prevalence and intensity of cutaneous manifestations depended on the nature of the pathological liver process and indirectly testified to its severity and activity. The symptoms of skin diseases were most pronounced in patients with autoimmune liver lesions, chronic toxic hepatitis, and cirrhosis.
authors.affiliation: Novosibirsk State Medical University, Ministry of Health of Russia, Novosibirsk, Russia.
authors.forename: O N
authors.initials: ON
authors.lastname: Pozdnyakova
authors.affiliation: Novosibirsk State Medical University, Ministry of Health of Russia, Novosibirsk, Russia.
authors.forename: O B
authors.initials: OB
authors.lastname: Nemchaninova
authors.affiliation: Novosibirsk State Medical University, Ministry of Health of Russia, Novosibirsk, Russia.
authors.forename: S G
authors.initials: SG
authors.lastname: Lykova
authors.affiliation: Novosibirsk State Medical University, Ministry of Health of Russia, Novosibirsk, Russia.
authors.forename: T B
authors.initials: TB
authors.lastname: Reshetnikova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D015897:Comorbidity; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology*; D008297:Male; D008659:Metabolic Diseases / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D012871:Skin Diseases / Q000453:epidemiology*; D055815:Young Adult