title: PulseCam: high-resolution blood perfusion imaging using a camera and a pulse oximeter.
abstract: Measuring blood perfusion is important in medical care as an indicator of injury and disease. However, currently available devices to measure blood perfusion like laser Doppler flowmetry are bulky, expensive, and cumbersome to use. An alternative low-cost and portable camera-based blood perfusion measurement system has recently been proposed, but such camera-only system produces noisy low-resolution blood perfusion maps. In this paper, we propose a new multi-sensor modality, named PulseCam, for measuring blood perfusion by combining a traditional pulse oximeter with a video camera in a unique way to provide low noise and high-resolution blood perfusion maps. Our proposed multi-sensor modality improves per pixel signal to noise ratio of measured perfusion map by up to 3 dB and improves the spatial resolution by 2 - 3 times compared to best known camera-only methods. Blood perfusion measured in the palm using our PulseCam setup during a post-occlusive reactive hyperemia (PORH) test replicates standard PORH response curve measured using laser Doppler flowmetry device but with much lower cost and a portable setup making it suitable for further development as a clinical device.
authors.forename: Mayank
authors.initials: M
authors.lastname: Kumar
authors.forename: James
authors.initials: J
authors.lastname: Suliburk
authors.forename: Ashok
authors.initials: A
authors.lastname: Veeraraghavan
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Sabharwal
mesh_terms: D005260:Female; D006225:Hand; D006801:Humans; D006940:Hyperemia; D007091:Image Processing, Computer-Assisted; D017078:Laser-Doppler Flowmetry; D016013:Likelihood Functions; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D010092:Oximetry / Q000379:methods*; D010477:Perfusion; D055420:Perfusion Imaging; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio; D012867:Skin; D014741:Video Recording / Q000295:instrumentation*