title: Phytochemical study and biological effects of the essential oil of Fraxinus dimorpha Coss & Durieu§.
abstract: The present study describes the phytochemical study, antioxidant and antimicrobial activities of Fraxinus dimorpha essential oil, obtained from the leaves collected in the High Atlas Mountains. Forty compounds representing 86.2% with (E)-nerolidol as a major constituent and 29 compounds corresponding to 80.3% with eugenol as main components were identified from Ait M'hamed and from Siti Fadma, respectively. The F. dimorpha essential oil presents IC50 using DPPH varying from 5.33 to 6.03 mg/mL and EC50 using FRAP varying from 0.83 to 1.21 mg/mL. The antimicrobial activity of the oil was evaluated for ten microorganisms showed that the oil had a moderate potential activity. Fungal strains are more sensitive to the investigated oils, with a MIC varied between 1.8 and 3.8 mg/mL.
authors.affiliation: a Laboratory of Applied Chemistry, Faculty of Sciences Semlalia , Cadi Ayyad University Marrakech , Marrakech , Morocco.|b Laboratory of Ecology and Environment, Faculty of Sciences Semlalia , Cadi Ayyad University Marrakech , Marrakech , Morocco.
authors.forename: Soufiane
authors.initials: S
authors.lastname: M'sou
authors.affiliation: b Laboratory of Ecology and Environment, Faculty of Sciences Semlalia , Cadi Ayyad University Marrakech , Marrakech , Morocco.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Alifriqui
authors.affiliation: a Laboratory of Applied Chemistry, Faculty of Sciences Semlalia , Cadi Ayyad University Marrakech , Marrakech , Morocco.
authors.forename: Abderrahmane
authors.initials: A
authors.lastname: Romane
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005054:Eugenol / Q000032:analysis / Q000494:pharmacology; D031661:Fraxinus / Q000737:chemistry*; D020128:Inhibitory Concentration 50; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D012717:Sesquiterpenes / Q000032:analysis / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D009822:Oils, Volatile; D012717:Sesquiterpenes; D005054:Eugenol; C037055:nerolidol
keywords: F.dimorpha; antimicrobial activity; antioxidant activity; essential oil