title: DNA Replication: How Does a Sliding Clamp Slide?
abstract: DNA sliding clamps are rings that tether certain enzymes to DNA. How clamp proteins slide on DNA has remained a mystery. A new crystal structure, together with molecular dynamics and NMR studies, has revealed how the human PCNA clamp slides on DNA.
authors.affiliation: The Rockefeller University, 1230 York Avenue, New York City, NY 10065, USA.
authors.forename: Nina Y
authors.initials: NY
authors.lastname: Yao
authors.affiliation: The Rockefeller University, 1230 York Avenue, New York City, NY 10065, USA; Howard Hughes Medical Institute, 1230 York Avenue, New York City, NY 10065, USA. Electronic address: odonnel@rockefeller.edu.
authors.forename: Mike
authors.initials: M
authors.lastname: O'Donnell
mesh_terms: D004247:DNA; D004261:DNA Replication; D006801:Humans; D056004:Molecular Dynamics Simulation; D018809:Proliferating Cell Nuclear Antigen / Q000235:genetics
chemical_list: D018809:Proliferating Cell Nuclear Antigen; D004247:DNA