title: Domestication drive the changes of immune and digestive system of Eurasian perch (Perca fluviatilis).
abstract: Domestication has altered a variety of traits within the Eurasian perch (Perca fluviatilis), including phenotypic, physiological and behavioral traits of Eurasian perch (Perca fluviatilis). Little is known, however, about the genetic changes between domesticated and wild Eurasian perch. In this study, we assembled a high-quality de novo reference transcriptome and identified differentially expressed genes between wild and domesticated Eurasian perch. A total of 113,709 transcripts were assembled, and 58,380 transcripts were annotated. Transcriptomic comparison revealed 630 differentially expressed genes between domesticated and wild Eurasian perch. Within domesticated Eurasian perch there were 412 genes that were up-regulated including MHCI, MHCII, chia, ighm within immune system development. There were 218 genes including try1, ctrl, ctrb, cela3b, cpa1 and cpb1, which were down-regulated that were associated with digestive processes. Our results indicated domestication drives the changes of immune and digestive system of Eurasian perch. Our study not only provide valuable genetic resources for further studies in Eurasian perch, but also provide novel insights into the genetic basis of physiological changes in Eurasian perch during domestication process.
authors.affiliation: Key Laboratory of Freshwater Fisheries Germplasm Resources, Ministry of Agriculture, Shanghai Ocean University, Shanghai, China.
authors.forename: Xiaowen
authors.initials: X
authors.lastname: Chen
authors.affiliation: Key Laboratory of Freshwater Fisheries Germplasm Resources, Ministry of Agriculture, Shanghai Ocean University, Shanghai, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.affiliation: Fisheries Technology Extension Station, Xinjiang Production and Construction Corps, Urumqi, Xinjiang, China.
authors.forename: Long
authors.initials: L
authors.lastname: Qian
authors.affiliation: Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America.
authors.forename: Sarah
authors.initials: S
authors.lastname: Gaughan
authors.affiliation: Fisheries Technology Extension Station, Xinjiang Production and Construction Corps, Urumqi, Xinjiang, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Xiang
authors.affiliation: Fisheries Technology Extension Station, Xinjiang Production and Construction Corps, Urumqi, Xinjiang, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Ai
authors.affiliation: Fisheries Technology Extension Station, Xinjiang Production and Construction Corps, Urumqi, Xinjiang, China.
authors.forename: Zhenming
authors.initials: Z
authors.lastname: Fan
authors.affiliation: Key Laboratory of Freshwater Fisheries Germplasm Resources, Ministry of Agriculture, Shanghai Ocean University, Shanghai, China.
authors.forename: Chenghui
authors.initials: C
authors.lastname: Wang
mesh_terms: D000818:Animals; D004064:Digestive System; D000071278:Domestication; D005786:Gene Expression Regulation / Q000235:genetics; D007107:Immune System; D010471:Perches / Q000235:genetics* / Q000502:physiology; D013312:Stress, Physiological / Q000235:genetics; D059467:Transcriptome / Q000235:genetics*