title: Pediatric Liver Transplant For Hepatoblastoma: A Single-Center Experience.
abstract: OBJECTIVE
  Our aim was to analyze our experience with orthotopic liver transplant for hepatoblastoma patients.
  
  
  METHODS
  We performed a single-center retrospective analysis of 6 orthotopic liver transplant cases in children with hepatoblastoma from 2001 to March 2015. We evaluated patient demographic features, pretreatment extent of disease stage, type of transplant, change in serum alpha-fetoprotein levels, complications, and follow-up results.
  
  
  RESULTS
  Orthotopic liver transplant was performed for pretreatment extent of disease stage III with a central location (n = 3) and pretreatment extent of disease stage IV (n = 3). All children underwent living-donor orthotopic liver transplant. Postoperative serum alpha-fetoprotein levels remained below 10 ng/mL during the follow-up period in 3 patients who were free of recurrences or metastases. Five patients were free of tumor recurrences at a median follow-up of 29.9 months.
  
  
  CONCLUSIONS
  The limited number of cases we present without long-term follow-up of orthotopic liver transplant for unresectable hepatoblastoma seemed to show good clinical results.
authors.affiliation: Department of Transplant Surgery, Baskent University, Ankara, Turkey.
authors.forename: Mahir
authors.initials: M
authors.lastname: Kirnap
authors.forename: Ebru
authors.initials: E
authors.lastname: Ayvazoglu Soy
authors.forename: Figen
authors.initials: F
authors.lastname: Ozcay
authors.forename: Gokhan
authors.initials: G
authors.lastname: Moray
authors.forename: Binnaz Handan
authors.initials: BH
authors.lastname: Ozdemir
authors.forename: Mehmet
authors.initials: M
authors.lastname: Haberal
mesh_terms: D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D018572:Disease-Free Survival; D005260:Female; D018197:Hepatoblastoma / Q000097:blood / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000097:blood / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods; D019520:Living Donors; D008297:Male; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014421:Turkey; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: C097353:AFP protein, human; D000509:alpha-Fetoproteins