abstract: Rupture of an atherosclerotic plaque is the usual initiating event in an acute coronary syndrome (ACS). Persistent thrombotic occlusion at the site of plaque rupture results in acute myocardial infarction. The early management of the patient is essential and crucially affects the prognosis of an ACS. Management includes the relief of ischemic pain and the initiation of an antithrombotic therapy, including an antiplatelet and anticoagulant therapy with aspirin and heparin to prevent further thrombosis of or embolism from an ulcerated plaque.
authors.affiliation: Clinique danesthésiologie, de médecine intensive, durgence et de la douleur, Hôpital cantonal de SaintGall, Saint-Gall, Switzerland.
authors.forename: Ali
authors.initials: A
authors.lastname: Yildirim
authors.forename: Heinz-Theo
authors.initials: HT
authors.lastname: Lübbers
authors.forename: Ayhan
authors.initials: A
authors.lastname: Yildirim
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D000925:Anticoagulants / Q000627:therapeutic use; D003328:Coronary Thrombosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D004359:Drug Therapy, Combination; D061345:Early Medical Intervention; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D058226:Plaque, Atherosclerotic / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011379:Prognosis; D012422:Rupture, Spontaneous
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors
keywords: Syndrome coronarien aigu