title: Sequential organ failure assessment score predicts mortality after coronary artery bypass grafting.
abstract: BACKGROUND
  Mortality after coronary artery bypass grafting (CABG) is generally associated with underlying disease and surgical factors overlooked in preoperative prognostic models. Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores are widely used in intensive care units for outcome prediction. This study investigated the accuracy of these models in predicting mortality.
  
  
  METHODS
  Between January 2010 and April 2013, 483 patients who underwent isolated CABG were enrolled. The clinical characteristics, outcomes, and prognostic model scores of the patients were collected. Discrimination was assessed using the area under the curve approach.
  
  
  RESULTS
  Both SOFA and APACHE II scores were effective for predicting in-hospital mortality. Among the organ systems examined in the SOFA, the cardiac and renal systems were the strongest predictors of CABG mortality. Multivariate analysis identified only the SOFA score as being an independent risk factor for mortality.
  
  
  CONCLUSIONS
  In summary, the SOFA score can be used to accurately identify mortality after isolated CABG.
authors.affiliation: Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Chih-Hsiang
authors.initials: CH
authors.lastname: Chang
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Shao-Wei
authors.initials: SW
authors.lastname: Chen
authors.affiliation: Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Pei-Chun
authors.initials: PC
authors.lastname: Fan
authors.affiliation: Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Cheng-Chia
authors.initials: CC
authors.lastname: Lee
authors.affiliation: Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Huang-Yu
authors.initials: HY
authors.lastname: Yang
authors.affiliation: Clinical Informatics and Medical Statistics Research Center, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Su-Wei
authors.initials: SW
authors.lastname: Chang
authors.affiliation: Department of Nephrology, Chang Gung Memorial Hospital, Keelung branch, New Taipei City, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Heng-Chih
authors.initials: HC
authors.lastname: Pan
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Feng-Chun
authors.initials: FC
authors.lastname: Tsai
authors.affiliation: Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.
authors.forename: Chih-Wei
authors.initials: CW
authors.lastname: Yang
authors.affiliation: Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan. cyc2356@cgmh.org.tw.|School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan. cyc2356@cgmh.org.tw.
authors.forename: Yung-Chang
authors.identifier: http://orcid.org/0000-0003-3062-8467
authors.initials: YC
authors.lastname: Chen
mesh_terms: D018806:APACHE; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology / Q000401:mortality*; D063305:Organ Dysfunction Scores; D011379:Prognosis; D012372:ROC Curve; D012307:Risk Factors; D012720:Severity of Illness Index
keywords: Cardiorenal syndrome; Coronary artery by pass grafting; Mortality; Sequential organ failure assessment; Society of thoracic surgeons mortality risk