title: Comparison of the Fractional Exhaled Nitric Oxide Levels in Adolescents at Three Schools Located Three Different Distances from a Large Steel Mill.
abstract: Objectives.Exposure to ambient metals and air pollutants in urban environments has been associated with impaired lung health and inflammation in the lungs. Fractional exhaled nitric oxide (FeNO) is a reliable marker of airway inflammation. In this study, we aimed to compare the FeNO levels of three schools that have different distances from iron and steel industry zone for assessing the effects of heavy metals and air pollution on their respiratory health.Methods.Pulmonary function test and FeNO measurements were evaluated in 387 adolescents in three schools which have different distance from plant.Results.FeNO levels were significantly higher in School I (n= 142; 18.89 ± 12.3 ppb) and School II (n= 131; 17.68 ± 7.7 ppb) than School III (n= 114; 4.28 ± 3.9 ppb). Increased FeNO concentration was related to the distance of iron and steel industry zone in young adults.Conclusion.The FeNO concentrations in school children were inversely proportional to the distance from the steel mill. There are needed some studies that can evaluate the safe distance and legislation must consider these findings.
authors.affiliation: Department of Pulmonology, Karabük University, Karabük, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Acat
authors.affiliation: Department of Pulmonology, Sakarya University, Sakarya, Turkey.
authors.forename: Yusuf
authors.identifier: 0000-0003-2479-2949
authors.initials: Y
authors.lastname: Aydemir
authors.affiliation: Department of Pulmonology, Adnan Menderes University, Aydın, Turkey.
authors.forename: Onur
authors.initials: O
authors.lastname: Yazıcı
authors.affiliation: Department of Pediatrics, Karabük University, Karabük, Turkey.
authors.forename: Mahmut
authors.initials: M
authors.lastname: Turğut
authors.affiliation: Department of Pulmonology, Karabük University, Karabük, Turkey.
authors.forename: Mustafa
authors.identifier: 0000-0002-6923-736X
authors.initials: M
authors.lastname: Çörtük
authors.affiliation: Department of Pediatric Surgery, Karabük University, Karabük, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Çakar
authors.affiliation: Department of Pulmonology, Abant Izzet Baysal University, Bolu, Turkey.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Yaşar
authors.affiliation: Clinic of Chest Diseases, Dr. Suat Seren Chest Diseases and Thoracic Surgery Training and Research Hospital, İzmir, Turkey.
authors.forename: Sami
authors.initials: S
authors.lastname: Deniz
authors.affiliation: Department of Pulmonology, Karabük University, Karabük, Turkey.
authors.forename: Erdoğan
authors.initials: E
authors.lastname: Çetinkaya
mesh_terms: D000293:Adolescent; D000397:Air Pollution / Q000009:adverse effects*; D001944:Breath Tests; D005260:Female; D006801:Humans; D008297:Male; D008669:Metallurgy; D019216:Metals, Heavy / Q000009:adverse effects*; D009569:Nitric Oxide / Q000032:analysis*; D012574:Schools / Q000706:statistics & numerical data
chemical_list: D019216:Metals, Heavy; D009569:Nitric Oxide