title: Initial comparison of energy measures for neural stimulation in a single conductance channel.
abstract: This paper considers the utility of several alternative energy measures to reduce the energy required by a stimulation current source to charge a neuron membrane capacitance to a prescribed value in the case of a single sodium channel. For a simple case, minimizing the energy of the nonlinear channel conductance provides improved efficiency in terms of stimulator energy as compared to minimizing a squared-integral measure of the stimulation current. This work lays the foundation for expanding this investigation to a full conductance-based Hodgkin-Huxley model.
authors.forename: John
authors.initials: J
authors.lastname: Stahl
authors.forename: Damon A
authors.initials: DA
authors.lastname: Miller
mesh_terms: D004558:Electric Stimulation / Q000379:methods*; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D059010:Single-Cell Analysis / Q000379:methods*; D015222:Sodium Channels / Q000502:physiology*
chemical_list: D015222:Sodium Channels