title: Lipid parameters in obese and normal weight patients with or without chronic periodontitis.
abstract: OBJECTIVE
  The aim of this study was to evaluate the serum levels of lipids in patients with normal weight (NW) or obesity with or without chronic periodontitis (ChP).
  
  
  METHODS
  One hundred and sixty non-smoking patients without history of diabetes and/or cardiovascular events were allocated into one of the following groups: NW patients with periodontal health (NWH; n = 40), NW patients with ChP (NWChP; n = 40), obese patients with periodontal health (ObH; n = 40), and obese patients with ChP (ObChP; n = 40). Serum levels of total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TRG) were estimated.
  
  
  RESULTS
  After adjustments for gender and age, both NW groups presented lower levels of TRG than both obese groups (p < 0.05). The NWH group presented lower levels of LDL than both periodontitis groups (p < 0.05) and the lowest TC/HDL ratio when compared to the other groups (p < 0.05). Females from the NWH group exhibited higher levels of HDL and lower LDL/HDL ratio than females from the ObChP group (p < 0.05). Furthermore, individuals from the ObChP group were more likely to have levels of LDL ≥130 mg/dl and HDL ≤40 mg/dl, compared to those from the NWH group (p < 0.05).
  
  
  CONCLUSIONS
  ChP and obesity, jointly or individually, are associated with undesirable pro-atherogenic lipid profiles.
  
  
  CONCLUSIONS
  There is interest in identifying clinical conditions associated with dyslipidemia to improve preventive and treatment strategies. This study demonstrated that ChP, obesity, and the association of both conditions might be related to pro-atherogenic lipid profiles.
authors.affiliation: Department of Periodontology, Guarulhos University, São Paulo, Brazil.
authors.forename: Eduardo Zaccarias
authors.initials: EZ
authors.lastname: Cury
authors.affiliation: Department of Periodontology, Guarulhos University, São Paulo, Brazil.
authors.forename: Vanessa Renata
authors.initials: VR
authors.lastname: Santos
authors.affiliation: Department of Periodontology, Guarulhos University, São Paulo, Brazil.
authors.forename: Suellen da Silva
authors.initials: SDS
authors.lastname: Maciel
authors.affiliation: Department of Periodontology, Guarulhos University, São Paulo, Brazil.|Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
authors.forename: Tiago Eduardo Dias
authors.initials: TED
authors.lastname: Gonçalves
authors.affiliation: Department of Periodontology, Guarulhos University, São Paulo, Brazil.
authors.forename: Glaucia Santos
authors.initials: GS
authors.lastname: Zimmermann
authors.affiliation: Department of Statistics and Applied Mathematics, Federal University of Ceará, Fortaleza, Ceará, Brazil.
authors.forename: Rosa Maria Salani
authors.initials: RMS
authors.lastname: Mota
authors.affiliation: Department of Periodontology, Guarulhos University, São Paulo, Brazil.
authors.forename: Luciene Cristina
authors.initials: LC
authors.lastname: Figueiredo
authors.affiliation: Department of Periodontology, Guarulhos University, São Paulo, Brazil. pduarte@ung.br.
authors.forename: Poliana Mendes
authors.initials: PM
authors.lastname: Duarte
mesh_terms: D000328:Adult; D055113:Chronic Periodontitis / Q000097:blood*; D050171:Dyslipidemias / Q000097:blood*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D012307:Risk Factors
chemical_list: D008055:Lipids
keywords: Chronic periodontitis; High-density lipoprotein cholesterol; Low-density lipoprotein cholesterol; Obesity; Total cholesterol; Triglycerides