title: Biotechnological Production of Organic Acids from Renewable Resources.
abstract: Biotechnological processes are promising alternatives to petrochemical routes for overcoming the challenges of resource depletion in the future in a sustainable way. The strategies of white biotechnology allow the utilization of inexpensive and renewable resources for the production of a broad range of bio-based compounds. Renewable resources, such as agricultural residues or residues from food production, are produced in large amounts have been shown to be promising carbon and/or nitrogen sources. This chapter focuses on the biotechnological production of lactic acid, acrylic acid, succinic acid, muconic acid, and lactobionic acid from renewable residues, these products being used as monomers for bio-based material and/or as food supplements. These five acids have high economic values and the potential to overcome the "valley of death" between laboratory/pilot scale and commercial/industrial scale. This chapter also provides an overview of the production strategies, including microbial strain development, used to convert renewable resources into value-added products.
authors.affiliation: Department of Bioengineering, Leibniz Institute for Agricultural Engineering and Bioeconomy Potsdam (ATB), Max-Eyth-Allee 100, 14469, Potsdam, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Pleissner
authors.affiliation: Department of Bioengineering, Leibniz Institute for Agricultural Engineering and Bioeconomy Potsdam (ATB), Max-Eyth-Allee 100, 14469, Potsdam, Germany.
authors.forename: Donna
authors.initials: D
authors.lastname: Dietz
authors.affiliation: Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
authors.forename: Jozef Bernhard Johann Henri
authors.initials: JBJH
authors.lastname: van Duuren
authors.affiliation: Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Wittmann
authors.affiliation: School of Energy and Environment, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Yang
authors.affiliation: School of Energy and Environment, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong.
authors.forename: Carol Sze Ki
authors.initials: CSK
authors.lastname: Lin
authors.affiliation: Department of Bioengineering, Leibniz Institute for Agricultural Engineering and Bioeconomy Potsdam (ATB), Max-Eyth-Allee 100, 14469, Potsdam, Germany. jvenus@atb-potsdam.de.
authors.forename: Joachim
authors.initials: J
authors.lastname: Venus
mesh_terms: D001709:Biotechnology; D002617:Chemical Industry / Q000379:methods / Q000639:trends; D019344:Lactic Acid / Q000096:biosynthesis; D064307:Microbiota; D009930:Organic Chemicals
chemical_list: D009930:Organic Chemicals; D019344:Lactic Acid
keywords: Acrylic acid; Cascade use of renewable resources; Lactic acid; Lactobionic acid; Muconic acid; Succinic acid