title: A new neolignan from Selaginella moellendorffii Hieron.
abstract: A new neolignan, selamoellenin A (1), was isolated from the whole plants of Selaginella moellendorffii Hieron. The structure was elucidated on the basis of comprehensive spectroscopic methods (1D/2D NMR and HRMS). Compound 1 was evaluated for its protective effect against high glucose-induced human umbilical vein endothelial cells (HUVECs) damage in vitro.
authors.affiliation: a Xiangya Hospital of Central South University , Changsha , PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zeng
authors.affiliation: b Xiangya School of Pharmaceutical Sciences , Central South University , Changsha , PR China.
authors.forename: Cai-Ping
authors.initials: CP
authors.lastname: Yao
authors.affiliation: a Xiangya Hospital of Central South University , Changsha , PR China.
authors.forename: Ping-Sheng
authors.initials: PS
authors.lastname: Xu
authors.affiliation: a Xiangya Hospital of Central South University , Changsha , PR China.
authors.forename: Guo-Gang
authors.initials: GG
authors.lastname: Zhang
authors.affiliation: a Xiangya Hospital of Central South University , Changsha , PR China.
authors.forename: Zhao-Qian
authors.initials: ZQ
authors.lastname: Liu
authors.affiliation: b Xiangya School of Pharmaceutical Sciences , Central South University , Changsha , PR China.
authors.forename: Kang-Ping
authors.initials: KP
authors.lastname: Xu
authors.affiliation: a Xiangya Hospital of Central South University , Changsha , PR China.|b Xiangya School of Pharmaceutical Sciences , Central South University , Changsha , PR China.
authors.forename: Zhen-Xing
authors.initials: ZX
authors.lastname: Zou
authors.affiliation: a Xiangya Hospital of Central South University , Changsha , PR China.|b Xiangya School of Pharmaceutical Sciences , Central South University , Changsha , PR China.
authors.forename: Gui-Shan
authors.initials: GS
authors.lastname: Tan
mesh_terms: D002478:Cells, Cultured; D061307:Human Umbilical Vein Endothelial Cells / Q000187:drug effects; D006801:Humans; D007004:Hypoglycemic Agents; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D020011:Protective Agents / Q000302:isolation & purification / Q000494:pharmacology; D032503:Selaginellaceae / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D007004:Hypoglycemic Agents; D017705:Lignans; D020011:Protective Agents
keywords: HUVECs; Selaginella; Selaginella moellendorffii Hieron; lignans; selamoellenin A