title: Ecthyma gangrenosum in a 3-month-old, previously healthy infant: A Case Report.
abstract: BACKGROUND
  Ecthyma gangrenosum (EG) is an aggressive cutaneous disease caused by local or systemic infection with Pseudomonas aeruginosa. EG is characterized by cutaneous manifestations ranging from nodule and papule, to necrotic ulceration with surrounding erythema, especially with black eschar or central crust. EG presents with characteristic skin lesions which is important to establish diagnosis of sepsis caused by P aeruginosa, a serious condition that can be treated efficiently if diagnosed early.
  
  
  METHODS
  A 3-month-old female infant was presented with characteristic skin lesions of EG and developed sepsis 3 days later.
  
  
  METHODS
  Ecthyma gangrenosum and sepsis caused by Pseudomonas aeruginosa.
  
  
  METHODS
  Meropenem was used in combination with ceftazidime at first and excision of necrotic skin lesions was performed later.
  
  
  RESULTS
  Cure.
  
  
  CONCLUSIONS
  Early recognition of EG plays an important role in providing appropriate empiric antibiotic treatment at early stage of sepsis, and improves the prognosis. Surgical excision may be helpful if no improvement was achieved via antibiotic treatment.
authors.affiliation: Department of Dermatology Department of Urology, The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Department of Dermatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.
authors.forename: Xiao-Ting
authors.initials: XT
authors.lastname: Zhang
authors.forename: Wan-Wan
authors.initials: WW
authors.lastname: Jin
authors.forename: Xin-Hua
authors.initials: XH
authors.lastname: Ma
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Yu
authors.forename: Xu-Hua
authors.initials: XH
authors.lastname: Tang
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002442:Ceftazidime / Q000627:therapeutic use; D005260:Female; D005734:Gangrene / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D007223:Infant; D000077731:Meropenem; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000601:surgery; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D017511:Pyoderma Gangrenosum / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D013845:Thienamycins / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; D002442:Ceftazidime; D000077731:Meropenem