title: Translation and validation of the 15-item Myasthenia Gravis Quality of life scale in Dutch.
abstract: The 15-item Myasthenia Gravis Quality of Life (MG-QOL15) scale has been developed to assess the health-related quality of life of patients with myasthenia gravis (MG). The aim of this study was to translate the original English version into Dutch and to test the test-retest reliability and construct validity.
  
  
  
  Fifty patients with MG were included. Test-retest reliability and internal consistency were assessed using the intraclass correlation coefficient (ICC) and the Cronbach α. Construct validity was assessed by testing 5 predefined hypotheses.
  
  
  
  A good test-retest reliability was confirmed with an ICC of 0.866. The Cronbach α was 0.93. The predefined hypotheses were confirmed in 80% of cases, which points to good construct validity.
  
  
  
  The Dutch MG-QOL15 has good test-retest reliability and good construct validity. It can be used for research in a Dutch-speaking population. It is also suitable for monitoring individual patients in clinical practice. Muscle Nerve 57: 206-211, 2018.
authors.affiliation: Department of Neurology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
authors.forename: Ellen
authors.initials: E
authors.lastname: Strijbos
authors.affiliation: Department of Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Fania R
authors.initials: FR
authors.lastname: Gärtner
authors.affiliation: Department of Neurology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Verschuuren
mesh_terms: D000203:Activities of Daily Living; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007167:Immunotherapy; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000523:psychology* / Q000628:therapy; D009426:Netherlands; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D014177:Translations
keywords: MG-QOL15; myasthenia gravis; outcome measure; translation; validation