title: Verification of a research prototype for hemodynamic analysis of cerebral aneurysms.
abstract: Owing to its clinical importance, there has been a growing body of research on understanding the hemodynamics of cerebral aneurysms. Traditionally, this work has been performed using general-purpose, state-of-the-art commercial solvers. This has meant requiring engineering expertise for making appropriate choices on the geometric discretization, time-step selection, choice of boundary conditions etc. Recently, a CFD research prototype has been developed (Siemens Healthcare GmbH, Prototype - not for diagnostic use) for end-to-end analysis of aneurysm hemodynamics. This prototype enables anatomical model preparation, hemodynamic computations, advanced visualizations and quantitative analysis capabilities. In this study, we investigate the accuracy of the hemodynamic solver in the prototype against a commercially available CFD solver ANSYS CFX 16.0 (ANSYS Inc., Canonsburg, PA, www.ansys.com) retrospectively on a sample of twenty patient-derived aneurysm models, and show good agreement of hemodynamic parameters of interest.
authors.forename: Takashi
authors.initials: T
authors.lastname: Suzuki
authors.forename: Cosmin
authors.initials: C
authors.lastname: Ioan Nita
authors.forename: Saikiran
authors.initials: S
authors.lastname: Rapaka
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takao
authors.forename: Viorel
authors.initials: V
authors.lastname: Mihalef
authors.forename: Soichiro
authors.initials: S
authors.lastname: Fujimura
authors.forename: Chihebeddine
authors.initials: C
authors.lastname: Dahmani
authors.forename: Puneet
authors.initials: P
authors.lastname: Sharma
authors.forename: Hiroya
authors.initials: H
authors.lastname: Mamori
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ishibashi
authors.forename: Thomas
authors.initials: T
authors.lastname: Redel
authors.forename: Makoto
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Murayama
mesh_terms: D006439:Hemodynamics; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology*; D008953:Models, Anatomic