title: Antenatal depression among women hospitalized due to threatened preterm labor in a high-risk pregnancy unit in Greece.
abstract: OBJECTIVE
  Estimates for the prevalence of antenatal depression vary widely across different studies and especially concerning high-risk pregnancies. Threatened preterm labor is the most common indication for antenatal obstetric hospitalization. The aim of this study was to screen for depressive symptoms among pregnant women hospitalized in a high-risk pregnancy unit due to threatened preterm labor and also to investigate possible associated risk factors.
  
  
  METHODS
  A total of 103 pregnant women admitted at >24 and <36 gestational weeks were eligible to participate in the study. The Greek version of the Edinburgh Postnatal Depression Scale (EPDS) was used to detect depressive symptoms on admission. A cutoff score of >13 was considered as indicative of depression. Possible associated risk factors were also investigated.
  
  
  RESULTS
  The prevalence of antenatal depression (score >13) was 24.3% (n = 25). In the multivariate analysis, antenatal depression was significantly correlated with thoughts of abortion (OR: 6.208; 95% CI: 1.141-33.765).
  
  
  CONCLUSIONS
  About one quarter of the pregnant women hospitalized in the HRPU due to threatened preterm labor were depressed based on the EPDS. Thoughts of abortion were associated with a sixfold increase in the risk of depression, while no associations were found between antenatal depression and other sociodemographic and obstetric parameters.
authors.affiliation: a Third Department of Obstetrics and Gynaecology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
authors.forename: Themistoklis
authors.initials: T
authors.lastname: Dagklis
authors.affiliation: a Third Department of Obstetrics and Gynaecology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Tsakiridis
authors.affiliation: a Third Department of Obstetrics and Gynaecology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
authors.forename: Foteini
authors.initials: F
authors.lastname: Chouliara
authors.affiliation: a Third Department of Obstetrics and Gynaecology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Mamopoulos
authors.affiliation: a Third Department of Obstetrics and Gynaecology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
authors.forename: David
authors.initials: D
authors.lastname: Rousso
authors.affiliation: a Third Department of Obstetrics and Gynaecology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Athanasiadis
authors.affiliation: b Department of Clinical Pharmacology, Faculty of Medicine , Aristotle University of Thessaloniki , Greece.
authors.forename: Georgios
authors.identifier: http://orcid.org/0000-0003-1641-9095
authors.initials: G
authors.lastname: Papazisis
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006115:Greece / Q000453:epidemiology; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007752:Obstetric Labor, Premature / Q000517:prevention & control / Q000523:psychology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000453:epidemiology*; D018566:Pregnancy, High-Risk / Q000523:psychology*; D011295:Prenatal Care / Q000523:psychology; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D055815:Young Adult
keywords: Antenatal depression; Edinburgh Postnatal Depression Scale; high-risk pregnancy; threatened preterm labor