title: A randomised trial comparing laparoscopy with laparotomy in the management of women with ruptured ectopic pregnancy.
abstract: BACKGROUND
  Ruptured ectopic pregnancy (REP) is a common gynaecological emergency in resource-poor settings, where laparotomy is the standard treatment despite laparoscopic surgery being regarded as the optimal treatment. There is a lack of prospective randomised data comparing laparoscopic surgery with laparotomy in the surgical management of women with REP.
  
  
  OBJECTIVE
  To compare operative laparoscopy with laparotomy in women with REP.
  
  
  METHODS
  This was a randomised parallel study. One hundred and forty women with suspected REP were randomised to undergo operative laparoscopy or laparotomy. The outcome measures were operating time, hospital stay, pain scores and analgesic requirements, blood transfusion, time to return to work, and time to full recovery.
  
  
  RESULTS
  Operating time was significantly longer in the laparoscopy group (67.3 v. 30.5 minutes, p&lt;0.001). Duration of hospital stay, pain scores and need for analgesia were significantly less in the laparoscopy group. Women in this group returned to work 8 days earlier and their time to full recovery was significantly shorter compared with those in the laparotomy group. Significantly more women undergoing laparotomy required blood transfusion than women in the laparoscopy group. In the latter group, 14.5% of women required blood transfusion compared with 26.5% in the laparotomy group (p=0.01).
  
  
  CONCLUSIONS
  Operative laparoscopy in women treated for REP is feasible in a resource-poor setting and is associated with significantly less morbidity and a quicker return to economic activity.
authors.affiliation: Department of Obstetrics and Gynaecology, Faculty of Health Sciences, School of Medicine, University of Pretoria and Kalafong Provincial Tertiary Hospital, Pretoria, South Africa. Leon.Snyman@up.ac.za.
authors.forename: L
authors.initials: L
authors.lastname: Snyman
authors.forename: T
authors.initials: T
authors.lastname: Makulana
authors.forename: J D
authors.initials: JD
authors.lastname: Makin