title: West African Ebola Virus Strains: Unstable and Ready to Invade?
abstract: Recent studies demonstrate that the Ebola virus glycoprotein (GP) acquired an A82V change during the West Africa epidemic and that this change altered the capacity of GP to be activated by host factors, enhancing infection of human cells. How this may alter the outcome of disease remains to be determined.
authors.affiliation: Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA. Electronic address: cbasler@gsu.edu.
authors.forename: Christopher F
authors.initials: CF
authors.lastname: Basler
mesh_terms: D000354:Africa, Western / Q000453:epidemiology; D029043:Ebolavirus; D058872:Epidemics; D006023:Glycoproteins; D019142:Hemorrhagic Fever, Ebola / Q000453:epidemiology*; D006801:Humans
chemical_list: D006023:Glycoproteins