title: All That Glitters Is Not Gold" - A Case of an Occult Foreign Body in the Lung with Elevated 2-[18F]-Fluoro-2-deoxy-D-glucose (FDG) Uptake Mimicking Bronchogenic Carcinoma.
abstract: Combined positron emission tomography/computed tomography (PET/CT) using the glucose analogue 2-[18F]-fluoro-2-deoxy-D-glucose (FDG) has become the standard of care in oncological patients. However, due to the non-specific nature of FDG uptake, there are many physiological variants and benign pathological entities that also demonstrate augmented glucose metabolism, such as inflammatory and infective processes. Undiagnosed and retained foreign bodies (occult foreign bodies) in the lung can induce inflammatory reaction consisting of polymorphonuclear neutrophils, macrophages, and granulation tissue resulting in intense FDG uptake because of high metabolic activity and cell turnover. Here, we present a case of an occult foreign body imitating a tumor on PET/CT.
authors.affiliation: Pulmonary and Critical Care Medicine, Saint Louis University School of Medicine.
authors.forename: Venkatkiran
authors.initials: V
authors.lastname: Kanchustambham
authors.affiliation: Internal Medicine, Saint Louis University School of Medicine.
authors.forename: Aaron
authors.initials: A
authors.lastname: Schenone
authors.affiliation: Pulmonary and Critical Care Medicine, Saint Louis University School of Medicine.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Reichardt
authors.affiliation: Pulmonary and Critical Care Medicine, Saint Louis University School of Medicine.
authors.forename: Swetha
authors.initials: S
authors.lastname: Saladi
authors.affiliation: Internal Medicine, Saint Louis University School of Medicine.
authors.forename: Kris
authors.initials: K
authors.lastname: Mehta
authors.affiliation: Division of Hematology and Oncology, Saint Louis University School of Medicine.
authors.forename: Nishant
authors.initials: N
authors.lastname: Poddar
authors.affiliation: Pulmonary and Critical Care Medicine, Saint Louis University School of Medicine.
authors.forename: David
authors.initials: D
authors.lastname: Stoeckel
keywords: fdg; foreign body aspiration (fba); foreign body granuloma; occult foreign body; pet/ct