title: Electrospun Micro/Nanofibers as Controlled Release Systems for Pheromones of Bactrocera oleae and Prays oleae.
abstract: New systems for the controlled release of 1,7-dioxaspiro[5.5]undecane and (Z)-7-tetradecenal, the sex pheromones of olive fruit fly, Bactrocera oleae, and olive moth, Prays oleae, respectively, were developed utilizing electrospun micro/nanofiber matrices from inexpensive, biodegradable polymers, namely polycaprolactone, cellulose acetate and polyhydroxybutyrate. The incorporation of the pheromones in 5, 10 and 20% w/w in the electrospinning polymer blends allowed for the production of fiber mats with variable loading levels and release rates, ensuring however in all cases the release of pheromones for more than 16 weeks. Laboratory bioassays and field trapping tests showed that the fiber mats obtained from electrospinning of polyhydroxybutyrate solution containing 5% w/w 1,7-dioxaspiro[5.5]undecane and polycaprolactone solution containing 5% w/w (Z)-7-tetradecenal were almost twice as effective in attracting B. oleae and P. oleae males, respectively, in comparison to the positive controls used.
authors.affiliation: Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece.
authors.forename: Stefanos
authors.initials: S
authors.lastname: Kikionis
authors.affiliation: Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece.
authors.forename: Efstathia
authors.initials: E
authors.lastname: Ioannou
authors.affiliation: Chemical Ecology and Natural Products Laboratory, Institute of Biosciences and Applications, NCSR "Demokritos", 15310, Ag. Paraskevi, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Konstantopoulou
authors.affiliation: Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece. roussis@pharm.uoa.gr.
authors.forename: Vassilios
authors.initials: V
authors.lastname: Roussis
mesh_terms: D000818:Animals; D001681:Biological Assay; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry*; D004560:Electricity; D007753:Laboratories; D007915:Lepidoptera / Q000737:chemistry* / Q000187:drug effects; D008297:Male; D055616:Microtechnology; D057139:Nanofibers / Q000737:chemistry*; D012724:Sex Attractants / Q000737:chemistry* / Q000494:pharmacology; D033621:Tephritidae / Q000737:chemistry* / Q000187:drug effects
chemical_list: D003692:Delayed-Action Preparations; D004337:Drug Carriers; D012724:Sex Attractants
keywords: Bactrocera oleae; Controlled release; Electrospinning; Micro/nanofibers; Prays oleae; Sex pheromones