title: Type I interferon signature may influence the effect of belimumab on immunoglobulin levels, including rheumatoid factor in Sjögren's syndrome.
authors.affiliation: Department of Biological and Medical Sciences, Rheumatology Clinic, University of Udine, Italy. luca.quartuccio@asuiud.sanita.fvg.it.
authors.forename: Luca
authors.initials: L
authors.lastname: Quartuccio
authors.affiliation: Department of Physiology, School of Medicine, National and Kapodistrian University of Athens, Greece.
authors.forename: Clio P
authors.initials: CP
authors.lastname: Mavragani
authors.affiliation: Department of Physiology, School of Medicine, National and Kapodistrian University of Athens, Greece.
authors.forename: Adrianos
authors.initials: A
authors.lastname: Nezos
authors.affiliation: Department of Biological and Medical Sciences, Rheumatology Clinic, University of Udine, Italy.
authors.forename: Saviana
authors.initials: S
authors.lastname: Gandolfo
authors.affiliation: Department of Physiology, School of Medicine, National and Kapodistrian University of Athens, Greece.
authors.forename: Athanasios G
authors.initials: AG
authors.lastname: Tzioufas
authors.affiliation: Department of Biological and Medical Sciences, Rheumatology Clinic, University of Udine, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: De Vita
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D000941:Antigens / Q000235:genetics; D002352:Carrier Proteins / Q000235:genetics; D054370:Chemokine CXCL9 / Q000235:genetics; D003598:Cytoskeletal Proteins / Q000235:genetics; D005260:Female; D019204:GTP-Binding Proteins / Q000235:genetics; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007370:Interferon Type I / Q000276:immunology; D007371:Interferon-gamma / Q000276:immunology; D008875:Middle Aged; D064547:Myxovirus Resistance Proteins / Q000235:genetics; D016601:RNA-Binding Proteins; D060888:Real-Time Polymerase Chain Reaction; D012217:Rheumatoid Factor / Q000276:immunology; D012859:Sjogren's Syndrome / Q000188:drug therapy* / Q000276:immunology; D016896:Treatment Outcome
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D061067:Antibodies, Monoclonal, Humanized; D000941:Antigens; C080810:CXCL9 protein, human; D002352:Carrier Proteins; D054370:Chemokine CXCL9; D003598:Cytoskeletal Proteins; C490287:GBP1 protein, human; C065888:IFI44 protein, human; C484290:IFIT1 protein, human; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D007370:Interferon Type I; C579071:MX1 protein, human; D064547:Myxovirus Resistance Proteins; D016601:RNA-Binding Proteins; C511911:belimumab; D007371:Interferon-gamma; D012217:Rheumatoid Factor; D019204:GTP-Binding Proteins