title: [Smoking and pharmacological interactions].
abstract: Cigarette smoking can affect drug metabolism via pharmacokinetic and pharmacodynamic mechanisms, and a sudden change in smoking status can render patients at risk of serious adverse reactions, eg. after clozapine. Patients should be regularly monitored with regard to their smoking status and extent of cigarette consumption and doses of relevant medications adjusted accordingly.
authors.forename: František
authors.initials: F
authors.lastname: Perlík
mesh_terms: D004347:Drug Interactions; D006801:Humans; D012907:Smoking; D014029:Tobacco Use Disorder / Q000188:drug therapy
keywords: drug interactions; pharmacokinetics pharmacodynamics.; smoking