title: Multipoint temperature monitoring in liver undergoing computed tomography-guided radiofrequency ablation with fiber Bragg grating probes.
abstract: In this work, we investigated the temperature increment experienced by biological tissue during radiofrequency ablation (RFA). The measurements were performed by using two custom-made thermal probes based on fiber optic sensors (fiber Bragg gratings, FBGs). The two probes embed a total of 9 FBGs. Experiments were performed during RFA of an ex vivo healthy porcine liver. The RFA heating module was equipped with 5 thermocouples. Results show that the temperature increment close to the applicator (i.e., 0.6 cm-0.7 cm) reaches the temperature which is set as a target on the RFA module (i.e., approximately 100 °C). The distance from the applicator also has an impact on the dynamics of the heating phenomenon: at short distances the tissue temperature reaches a steady state condition after a few minutes, on the other hand the sensors placed at a distance ≥2cm did not reach the steady-state conditions during the 14-minute procedure. The multipoint temperature monitoring, which uses sensors at several distances from the applicator, can provide useful information regarding the boundary of damaged volume. This approach can be combined with the monitoring temperature system embedded in the heating equipment, to better control the damaged volume, and to improve the treatment outcomes.
authors.forename: P
authors.initials: P
authors.lastname: Saccomandi
authors.forename: E
authors.initials: E
authors.lastname: Schena
authors.forename: M
authors.initials: M
authors.lastname: Diana
authors.forename: F M
authors.initials: FM
authors.lastname: Di Matteo
authors.forename: G
authors.initials: G
authors.lastname: Costamagna
authors.forename: J
authors.initials: J
authors.lastname: Marescaux
mesh_terms: D000818:Animals; D017115:Catheter Ablation / Q000295:instrumentation*; D005336:Fiber Optic Technology / Q000295:instrumentation; D008099:Liver / Q000601:surgery*; D016343:Monitoring, Intraoperative / Q000295:instrumentation*; D025321:Surgery, Computer-Assisted; D013552:Swine; D013696:Temperature; D014057:Tomography, X-Ray Computed