title: Renal function is similar in solitary kidneys from patients with and without diabetes.
abstract: OBJECTIVE
  Due to the shortage of living kidney donors and the current diabetes mellitus (DM) pandemic, studying the association of solitary kidney (SK) with DM is of paramount importance. Our aim was to assess the significance of the association between SK and DM.
  
  
  METHODS
  Eighty-four patients with SK and DM (group A), with a mean age of 62.46±12.72 years, of whom 36 were males and 48 were females, were enrolled in the study. The control group (group B) comprised 84 SK patients without DM of similar age and duration of existence of a SK. Mean age: 61.58±8.22 years, 23 males and 61 females. Serum creatinine, GFR (CKD-EPI), glycaemia, cholesterol, triglycerides, uric acid, proteinuria/24h, systolic blood pressure (SBP), diastolic blood pressure (DBP) and BMI were assessed.
  
  
  RESULTS
  The group of patients with SK and DM (group A) had a higher BMI (p=0.0007), higher metabolic abnormalities (higher glycaemia [p<0.001], triglycerides [p=0.0004], uric acid [p=0.019] and proteinuria/24h [p=0.006]). The study group also had a higher prevalence of hypertension (p=0.003) and coronary artery disease (p=0.031).
  
  
  CONCLUSIONS
  We found a higher value of proteinuria in the study group, significant metabolic abnormalities, as well as a higher prevalence of hypertension and coronary artery disease. However, no differences with respect to GFR were found, which could have significant implications for transplantation.
authors.affiliation: Division of Nephrology, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania. Electronic address: gluhovschi@yahoo.com.
authors.forename: Cristina
authors.initials: C
authors.lastname: Gluhovschi
authors.affiliation: Division of Nephrology, Romanian Academy of Medical Sciences, Emergency County Clinical Hospital, Timisoara, Romania.
authors.forename: Gheorghe
authors.initials: G
authors.lastname: Gluhovschi
authors.affiliation: Division of Nephrology, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania; Emergency County Clinical Hospital, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania.
authors.forename: Florica
authors.initials: F
authors.lastname: Gadalean
authors.affiliation: Division of Nephrology, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania; Emergency County Clinical Hospital, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania.
authors.forename: Silvia
authors.initials: S
authors.lastname: Velciov
authors.affiliation: Division of Nephrology, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania; Emergency County Clinical Hospital, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania.
authors.forename: Ligia
authors.initials: L
authors.lastname: Petrica
authors.affiliation: Emergency County Clinical Hospital, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania; Department of Medical Informatics and Biostatistics, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania.
authors.forename: Bogdan
authors.initials: B
authors.lastname: Timar
authors.affiliation: Emergency County Clinical Hospital, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania; Department of Biochemistry, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania.
authors.forename: Adriana
authors.initials: A
authors.lastname: Kaycsa
authors.affiliation: Emergency County Clinical Hospital, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania; Department of Diabetes and Nutritional Diseases, University of Medicine and Pharmacy "V.Babes", Timisoara, Romania.
authors.forename: Romulus
authors.initials: R
authors.lastname: Timar
mesh_terms: D003920:Diabetes Mellitus / Q000503:physiopathology*; D003928:Diabetic Nephropathies / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D000075529:Solitary Kidney / Q000150:complications / Q000503:physiopathology*
keywords: Diabetes Mellitus (DM); Diabetes mellitus (DM); Proteinuria; Riñón único (SK); Solitary kidney (SK)