title: Dramatic resuscitation with Intralipid in an epinephrine unresponsive cardiac arrest following overdose of amitriptyline and propranolol.
abstract: Amitriptyline and propranolol are life threatening in overdose. The efficacy of intravenous lipid emulsion (ILE) in tricyclic antidepressant and propranolol overdose is unclear. We report a dramatic response to ILE following pulseless electrical activity arrest due to mixed amitriptyline and propranolol overdose.
authors.affiliation: Critical Care Unit, Royal United Hospital, Bath, Somerset, UK.
authors.forename: Philippe
authors.initials: P
authors.lastname: Le Fevre
authors.affiliation: Department of Medical Education/Emergency Medicine, Royal United Hospital, Bath, Somerset, UK.
authors.forename: Mark
authors.initials: M
authors.lastname: Gosling
authors.affiliation: Critical Care Unit, Royal United Hospital, Bath, Somerset, UK.
authors.forename: Keyur
authors.initials: K
authors.lastname: Acharya
authors.affiliation: Critical Care Unit, Royal United Hospital, Bath, Somerset, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: Georgiou
mesh_terms: D000328:Adult; D000639:Amitriptyline / Q000506:poisoning*; D062787:Drug Overdose / Q000209:etiology / Q000628:therapy*; D004837:Epinephrine / Q000008:administration & dosage; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage*; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced* / Q000628:therapy*; D006801:Humans; D011433:Propranolol / Q000506:poisoning*; D012151:Resuscitation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D005217:Fat Emulsions, Intravenous; D000639:Amitriptyline; D011433:Propranolol; D004837:Epinephrine