title: Chemical Composition of Volatiles; Antimicrobial, Antioxidant and Cholinesterase Inhibitory Activity of Chaerophyllum aromaticum L. (Apiaceae) Essential Oils and Extracts.
abstract: The present study reports the chemical composition of the headspace volatiles (HS) and essential oils obtained from fresh Chaerophyllum aromaticum root and aerial parts in full vegetative phase, as well as biological activities of their essential oils and MeOH extracts. In HS samples, the most dominant components were monoterpene hydrocarbons. On the other hand, the essential oils consisted mainly of sesquiterpenoids, representing 73.4% of the root and 63.4% of the aerial parts essential oil. The results of antibacterial assay showed that the aerial parts essential oil and MeOH extract have no antibacterial activity, while the root essential oil and extract showed some activity. Both of the tested essential oils exhibited anticholinesterase activity (47.65% and 50.88%, respectively); MeOH extract of the root showed only 8.40% inhibition, while aerial part extract acted as an activator of cholinesterase. Regarding the antioxidant activity, extracts were found to be more effective than the essential oils.
authors.affiliation: Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia.
authors.forename: Goran M
authors.initials: GM
authors.lastname: Petrović
authors.affiliation: Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia.
authors.forename: Jelena G
authors.initials: JG
authors.lastname: Stamenković
authors.affiliation: Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia.
authors.forename: Ivana R
authors.initials: IR
authors.lastname: Kostevski
authors.affiliation: Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia.
authors.forename: Gordana S
authors.initials: GS
authors.lastname: Stojanović
authors.affiliation: Department of Chemistry, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia.
authors.forename: Violeta D
authors.initials: VD
authors.lastname: Mitić
authors.affiliation: Department of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, Višegradska 33, 18000, Niš, Serbia.
authors.forename: Bojan K
authors.initials: BK
authors.lastname: Zlatković
mesh_terms: D000890:Anti-Infective Agents; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D019661:Apiaceae / Q000737:chemistry*; D002800:Cholinesterase Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D039821:Monoterpenes / Q000302:isolation & purification; D009822:Oils, Volatile / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D012717:Sesquiterpenes / Q000302:isolation & purification
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D002800:Cholinesterase Inhibitors; D039821:Monoterpenes; D009822:Oils, Volatile; D010936:Plant Extracts; D012717:Sesquiterpenes
keywords: 
  Chaerophyllum aromaticum
  ; Biological activities; Essential oils