title: Particulate matter (PM10) exposure, birth and fetal-placental weight and umbilical arterial pH: results from a prospective study.
abstract: OBJECTIVE
  This prospective study aims to analyze the relation between particulate matter (PM10) exposure during pregnancy and birth weight (BW), placental weight (PW) and umbilical artery PH (UAPH).
  
  
  METHODS
  Population included 3614 women born in Italy, living in Lombardia Region, consecutively admitted to the Clinica Mangiagalli for an elective cesarean section from January 2004 through December 2006. Outdoor air quality data were provided by the Department of the Regional Environmental Protection Agency and obtained by a network of fixed monitoring stations representatively distributed in eight geographical areas.
  
  
  CONCLUSIONS
  Birth weight was negatively associated with exposure to PM10concentration during the first trimester of pregnancy (mean change -22.2 g, 95%CI -8.7 to -35.7, p = 0.0013). Placental weight and umbilical artery PH were not associated with exposure to PM10concentration. Fetal weight was negatively associated with exposure to PM10concentration during the first trimester of pregnancy.
authors.affiliation: a Dipartimento Materno infantile IRCCS Fondazione Policlinico Mangiagalli Regina Elena , Università degli Studi di Milano , Milano , Italy.
authors.forename: Niccolò
authors.initials: N
authors.lastname: Giovannini
authors.affiliation: b School of Nursing and Midwifery, Griffith University , Brisbane , Australia.
authors.forename: Lianne
authors.initials: L
authors.lastname: Schwartz
authors.affiliation: a Dipartimento Materno infantile IRCCS Fondazione Policlinico Mangiagalli Regina Elena , Università degli Studi di Milano , Milano , Italy.
authors.forename: Sonia
authors.initials: S
authors.lastname: Cipriani
authors.affiliation: a Dipartimento Materno infantile IRCCS Fondazione Policlinico Mangiagalli Regina Elena , Università degli Studi di Milano , Milano , Italy.|c Dipartimento Scienze Cliniche e di Comunità , Università di Milano , Milano , Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Parazzini
authors.affiliation: a Dipartimento Materno infantile IRCCS Fondazione Policlinico Mangiagalli Regina Elena , Università degli Studi di Milano , Milano , Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Baini
authors.affiliation: d Dipartimento Materno Infantile , Istituti Clinici di Perfezionamento , Milano , Italy.
authors.forename: Valentina
authors.initials: V
authors.lastname: Signorelli
authors.affiliation: e Dipartimento di Scienze Biologiche e Cliniche , University of Milan, Sacco Hospital , Milan , Italy.
authors.forename: Irene
authors.initials: I
authors.lastname: Cetin
mesh_terms: D000328:Adult; D000393:Air Pollutants / Q000633:toxicity*; D000397:Air Pollution / Q000009:adverse effects*; D001724:Birth Weight; D005260:Female; D020567:Fetal Weight; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007558:Italy; D008297:Male; D018811:Maternal Exposure / Q000009:adverse effects*; D052638:Particulate Matter / Q000633:toxicity*; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy; D011446:Prospective Studies; D014469:Umbilical Arteries / Q000737:chemistry
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter
keywords: Air pollution; birth weight; epidemiology; placental weight; umbilical artery pH