title: Frequency of motor alterations detected through manometry in patients with esophageal symptoms and scleroderma.
abstract: BACKGROUND
  Scleroderma can present with esophageal involvement causing important morbidity.
  
  
  OBJECTIVE
  To describe the manometric findings and clinical characteristics of patients with scleroderma and esophageal symptoms.
  
  
  METHODS
  Patients with scleroderma and esophageal symptoms were evaluated through esophageal manometry within the time frame of one year. Descriptive statistics were carried out and the continuous variables were expressed as means and standard deviation. Frequencies were expressed as percentages.
  
  
  RESULTS
  The study included 24 female patients with a mean age of 53.5 years and mean disease progression of 7.84 years. The most frequent findings were short and hypotonic lower esophageal sphincter (mean length 1.58cm and mean tone 9.49mmHg) and ineffective esophageal motility (mean non-transmitted waves 92.91%, mean effective primary peristalsis 40.05%, and mean amplitude 13.11mmHg). The most frequent symptom was dysphagia.
  
  
  CONCLUSIONS
  Scleroderma is associated with lower esophageal sphincter alterations and symptomatic ineffective esophageal motility.
authors.affiliation: Laboratorio de Motilidad Gastrointestinal y Clínica de ERGE y trastornos funcionales digestivos, Hospital Juárez de México, SSA, Ciudad de México, México. Electronic address: sonelle74@hotmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Pérez Y López
authors.affiliation: División de Medicina, Hospital Juárez de México, SSA, Ciudad de México, México.
authors.forename: G
authors.initials: G
authors.lastname: Lugo-Zamudio
authors.affiliation: Servicio de Reumatología, Hospital Juárez de México, SSA, Ciudad de México, México.
authors.forename: R E
authors.initials: RE
authors.lastname: Barbosa-Cobos
authors.affiliation: Servicio de Reumatología, Hospital Juárez de México, SSA, Ciudad de México, México.
authors.forename: A
authors.initials: A
authors.lastname: Wong-Lam
authors.affiliation: Servicio de Cirugía General, Hospital Ángeles Lindavista, Ciudad de México, México.
authors.forename: E
authors.initials: E
authors.lastname: Torres-López
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018450:Disease Progression; D015154:Esophageal Motility Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D049630:Esophageal Sphincter, Lower / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D055815:Young Adult
keywords: Esclerodermia; Esfínter esofágico inferior; Esophageal manometry; Esophagus; Esófago; Lower esophageal sphincter; Manometría esofágica; Peristalsis; Scleroderma