title: Exploring flow rate selection in HIPEC procedures.
abstract: Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has emerged as a main comprehensive treatment of peritoneal malignancies. However, current data on the literature are very heterogeneous in terms of its technical particularities, which require some efforts to standardization of practices. In these setting, we present some early data from a pioneering clinical trial in Brazil (ClinicalTrials.gov Identifier: NCT02249013) to explore the dynamic relationships between flow rates and temperature parameters in the first cases of our study, which may help in selecting better technical parameters during HIPEC procedures.
authors.affiliation: Department of Surgery, Pernambucan Health Faculty, Professor Fernando Figueira Institute of Integral Medicine, Recife, Pernambuco, Brazil.
authors.forename: Thales Paulo
authors.initials: TP
authors.lastname: Batista
authors.affiliation: Department of Gynecology, A.C. Camargo Cancer Center, São Paulo, São Paulo, Brasil.
authors.forename: Levon
authors.initials: L
authors.lastname: Badiglian Filho
authors.affiliation: Department of Surgery, Pernambucan Health Faculty, Professor Fernando Figueira Institute of Integral Medicine, Recife, Pernambuco, Brazil.
authors.forename: Cristiano Souza
authors.initials: CS
authors.lastname: Leão
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols; D001938:Brazil; D010478:Chemotherapy, Cancer, Regional Perfusion; D003131:Combined Modality Therapy; D006801:Humans; D006979:Hyperthermia, Induced; D010534:Peritoneal Neoplasms / Q000628:therapy*