title: Phytochemical components and biological activities of Silene arenarioides Desf.
abstract: In this study, six known compounds 1-6 were isolated from the aerial parts of Silene arenarioides Desf. using different chromatographic methods. The structures of these compounds were identified as maltol glycoside (1), soyacerebroside I (2), chrysin (3), apigenin (4), quercetin (5) and stigmasterol glucoside (6). The compounds (1) and (2) are reported for the first time from this genus. The isolated compounds were determined using NMR techniques (1H NMR,13C NMR, COSY, HSQC and HMBC) and mass spectroscopy (ESI-MS). The antibacterial and antioxidant activities of extracts and of compound (1) have been evaluated. The antioxidant activity was performed by DPPH radical scavenging method, which showed that methanol extract possesses a good antioxidant activity with value of IC50= 8.064 ± 0.005 μg/mL.
authors.affiliation: a Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Faculté des Sciences de la Matière, Département de Chimie , Université de Batna-1 , Batna , Algérie.|b Département des Sciences de la Matière , Université de Khenchela , Khenchela , Algérie.
authors.forename: Lynda
authors.initials: L
authors.lastname: Golea
authors.affiliation: a Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Faculté des Sciences de la Matière, Département de Chimie , Université de Batna-1 , Batna , Algérie.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Benkhaled
authors.affiliation: c UMR CNRS 7312 , Institut de Chimie Moléculaire de Reims , Reims , France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Lavaud
authors.affiliation: d Pôle Actifs Végétaux- Recherche Substances Naturelles Centre de R & D Pierre Fabre , Toulouse , France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Long
authors.affiliation: a Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Faculté des Sciences de la Matière, Département de Chimie , Université de Batna-1 , Batna , Algérie.
authors.forename: Hamada
authors.initials: H
authors.lastname: Haba
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D047310:Apigenin / Q000032:analysis / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005419:Flavonoids / Q000032:analysis / Q000737:chemistry; D005960:Glucosides / Q000032:analysis / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D011794:Quercetin / Q000032:analysis / Q000494:pharmacology; D029751:Silene / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013265:Stigmasterol / Q000031:analogs & derivatives / Q000032:analysis / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D005419:Flavonoids; D005960:Glucosides; D006027:Glycosides; D010936:Plant Extracts; C464587:stigmasterol glucoside; C043561:chrysin; D047310:Apigenin; D013265:Stigmasterol; D011794:Quercetin
keywords: Silene arenarioides Desf.; antibacterial activity; antioxidant activity; maltol; soyacerebroside