title: Distribution and bioaccumulation of endocrine disrupting chemicals in water, sediment and fishes in a shallow Chinese freshwater lake: Implications for ecological and human health risks.
abstract: The occurrence, distribution and bioaccumulation of six endocrine disrupting compounds (EDCs) were investigated in water, sediment and biota samples from Luoma Lake, a shallow Chinese freshwater lake. Total concentrations of ∑phenolic EDCs were much higher than ∑estrogens EDCs in both waters and sediments. There were not obvious differences on the concentrations of target compounds [except nonylphenol (NP)] in upstream, lake and downstream locations, these may be suggested that they were mainly affected by non-point discharges in this area. However, the high concentration of NP in water may be associated with the discharge of rural domestic wastewater without thorough treatment. Furthermore, concentrations of NP were about 2-3 order magnitude higher than those of OP in both water and sediment compartments. Relatively higher bioaccumulation factors (BAF) were obtained for DES and EE2. Ecological risk assessment revealed greater risk of NP in surface water, which may pose a serious threat to aquatic ecosystems. The estrogen equivalent concentration (EEQ) of male were higher than those in female, and occurred in the order of city >rural-urban>countryside.
authors.affiliation: Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, No.8 Jiangwangmiao Street, 210042 Nanjing, China; College of Chemistry and Molecular Engineering, Nanjing Tech University, No.30 Puzhu Road(s), Nanjing 211816, China.
authors.lastname: Dan Liu
authors.affiliation: Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, No.8 Jiangwangmiao Street, 210042 Nanjing, China.
authors.forename: Shengmin
authors.initials: S
authors.lastname: Wu
authors.affiliation: Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, No.8 Jiangwangmiao Street, 210042 Nanjing, China.
authors.forename: Huaizhou
authors.initials: H
authors.lastname: Xu
authors.affiliation: Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, No.8 Jiangwangmiao Street, 210042 Nanjing, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, No.8 Jiangwangmiao Street, 210042 Nanjing, China. Electronic address: zsh@nies.org.
authors.forename: Shenghu
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, No.8 Jiangwangmiao Street, 210042 Nanjing, China. Electronic address: sll@nies.org.
authors.forename: Lili
authors.initials: L
authors.lastname: Shi
authors.affiliation: College of Chemistry and Molecular Engineering, Nanjing Tech University, No.30 Puzhu Road(s), Nanjing 211816, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Yao
authors.affiliation: Key laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education) & School of Science, China Pharmaceutical University, Nanjing 211198, China.
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Second Institute of Oceanography, State Oceanic Administration, Hangzhou 310013, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Cheng
mesh_terms: D000818:Animals; D058448:Biota; D004463:Ecology; D052244:Endocrine Disruptors / Q000032:analysis / Q000378:metabolism*; D004784:Environmental Monitoring; D005260:Female; D005399:Fishes / Q000378:metabolism*; D019015:Geologic Sediments / Q000737:chemistry; D006801:Humans; D060106:Lakes / Q000737:chemistry; D008297:Male; D010636:Phenols / Q000633:toxicity; D045483:Rivers / Q000737:chemistry; D062065:Wastewater / Q000737:chemistry; D014867:Water / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000378:metabolism*
chemical_list: D052244:Endocrine Disruptors; D010636:Phenols; D062065:Wastewater; D014867:Water; D014874:Water Pollutants, Chemical; C025256:nonylphenol
keywords: Bioaccumulation; Distribution; Endocrine disrupting chemicals; Environmental risk assessment; Freshwater lake; Human health impact