title: Effectiveness of a selective alcohol prevention program targeting personality risk factors: Results of interaction analyses.
abstract: To explore whether specific groups of adolescents (i.e., scoring high on personality risk traits, having a lower education level, or being male) benefit more from the Preventure intervention with regard to curbing their drinking behaviour.
  
  
  
  A clustered randomized controlled trial, with participants randomly assigned to a 2-session coping skills intervention or a control no-intervention condition.
  
  
  
  Fifteen secondary schools throughout The Netherlands; 7 schools in the intervention and 8 schools in the control condition.
  
  
  
  699 adolescents aged 13-15; 343 allocated to the intervention and 356 to the control condition; with drinking experience and elevated scores in either negative thinking, anxiety sensitivity, impulsivity or sensation seeking.
  
  
  
  Differential effectiveness of the Preventure program was examined for the personality traits group, education level and gender on past-month binge drinking (main outcome), binge frequency, alcohol use, alcohol frequency and problem drinking, at 12months post-intervention.
  
  
  
  Preventure is a selective school-based alcohol prevention programme targeting personality risk factors. The comparator was a no-intervention control.
  
  
  
  Intervention effects were moderated by the personality traits group and by education level. More specifically, significant intervention effects were found on reducing alcohol use within the anxiety sensitivity group (OR=2.14, CI=1.40, 3.29) and reducing binge drinking (OR=1.76, CI=1.38, 2.24) and binge drinking frequency (β=0.24, p=0.04) within the sensation seeking group at 12months post-intervention. Also, lower educated young adolescents reduced binge drinking (OR=1.47, CI=1.14, 1.88), binge drinking frequency (β=0.25, p=0.04), alcohol use (OR=1.32, CI=1.06, 1.65) and alcohol use frequency (β=0.47, p=0.01), but not those in the higher education group. Post hoc latent-growth analyses revealed significant effects on the development of binge drinking (β=-0.19, p=0.02) and binge drinking frequency (β=-0.10, p=0.03) within the SS personality trait.
  
  
  
  The alcohol selective prevention program Preventure appears to have effect on the prevalence of binge drinking and alcohol use among specific groups in young adolescents in the Netherlands, particularly the SS personality trait and lower educated adolescents.
authors.affiliation: Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Utrecht, The Netherlands. Electronic address: jlammers@trimbos.nl.
authors.forename: Jeroen
authors.initials: J
authors.lastname: Lammers
authors.affiliation: Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Utrecht, The Netherlands. Electronic address: fgoossens@trimbos.nl.
authors.forename: Ferry
authors.initials: F
authors.lastname: Goossens
authors.affiliation: Department of Psychological Medicine and Psychiatry, Section of Addiction, Kings College London, University of London, United Kingdom. Electronic address: patricia.conrod@kcl.ac.uk.
authors.forename: Patricia
authors.initials: P
authors.lastname: Conrod
authors.affiliation: Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Utrecht, The Netherlands; Behavioural Science Institute, Radboud University Nijmegen, The Netherlands. Electronic address: rengels@trimbos.nl.
authors.forename: Rutger
authors.initials: R
authors.lastname: Engels
authors.affiliation: Addiction, Development and Psychopathology (ADAPT) Lab, Department of Psychology, University of Amsterdam, The Netherlands. Electronic address: r.wiers@uva.nl.
authors.forename: Reinout W
authors.initials: RW
authors.lastname: Wiers
authors.affiliation: Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Utrecht, The Netherlands. Electronic address: mkleinjan@trimbos.nl.
authors.forename: Marloes
authors.initials: M
authors.lastname: Kleinjan
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D063425:Binge Drinking / Q000517:prevention & control; D016000:Cluster Analysis; D005260:Female; D006801:Humans; D008297:Male; D009426:Netherlands; D010551:Personality; D015397:Program Evaluation / Q000379:methods / Q000706:statistics & numerical data*; D012307:Risk Factors; D012572:School Health Services; D000066608:Underage Drinking / Q000517:prevention & control*
keywords: Adolescence; Alcohol use; Binge drinking; Education level; Personality traits; Selective prevention