title: Neurological findings spectrum in Celiac disease.
abstract: We aimed to provide early diagnosis by determining possible Celiac disease related subclinical or symptomatic neurological abnormalities in children in order to decrease risk of mortality and morbidity. Children with Celiac disease were assessed with neurological examination, neurophysiological tests and neuroimaging. A total of 65 patients were included in the study. The neurological examination was abnormal in 4 patients. There were EEG abnormalities in 5 patients, VEP was abnormal in 7 patients, BAER was abnormal in 1 patient, ENMG was abnormal in 8 patients, and there were abnormal findings on neuroimaging in 2 patients. The Celiac disease related neurological complications that manifest in adulthood usually lay their foundations in childhood. Therefore, it must be kept in mind that subclinical neurological abnormalities may be related to Celiac disease, and Celiac disease may be the underlying cause in the patients with overt neurological abnormalities in childhood.
authors.affiliation: Department of Pediatric Neurology, Dr. Sami Ulus Maternity and Childrens' Health and Diseases Training and Research Hospital, Ankara, Turkey.
authors.forename: Erhan
authors.initials: E
authors.lastname: Aksoy
authors.affiliation: Division of Pediatric Gastroenterology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: Serap
authors.initials: S
authors.lastname: Tıraş-Teber
authors.affiliation: Division of Pediatric Gastroenterology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: Aydan
authors.initials: A
authors.lastname: Kansu
authors.affiliation: Division of Pediatric Gastroenterology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: Gülhis
authors.initials: G
authors.lastname: Deda
authors.affiliation: Division of Pediatric Neurology, Department of Pediatrics, Selçuk University Faculty of Medicine, Konya, Turkey.
authors.forename: Ayşe
authors.initials: A
authors.lastname: Kartal
mesh_terms: D000293:Adolescent; D002446:Celiac Disease / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D016057:Evoked Potentials, Auditory, Brain Stem; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*; D059906:Neuroimaging; D012189:Retrospective Studies
keywords: celiac disease; children; neuroimaging; neurophysiologic study