title: Psychometric evaluation of the pediatric and parent-proxy Patient-Reported Outcomes Measurement Information System and the Neurology and Traumatic Brain Injury Quality of Life measurement item banks in pediatric traumatic brain injury.
abstract: The primary objective is to provide evidence of convergent and discriminant validity for the pediatric and parent-proxy versions of the Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety, Depression, Anger, Peer Relations, Mobility, Pain Interference, and Fatigue item banks, the Neurology Quality of Life measurement system (Neuro-QOL) Cognition-General Concerns and Stigma item banks, and the Traumatic Brain Injury Quality of Life (TBI-QOL) Executive Function and Headache item banks in a pediatric traumatic brain injury (TBI) sample.
  
  
  
  Participants were 134 parent-child (ages 8-18 years) days. Children all sustained TBI and the dyads completed outcome ratings 6 months after injury at one of six medical centers across the United States. Ratings included PROMIS, Neuro-QOL, and TBI-QOL item banks, as well as the Pediatric Quality of Life inventory (PedsQL), the Health Behavior Inventory (HBI), and the Strengths and Difficulties Questionnaire (SDQ) as legacy criterion measures against which these item banks were validated.
  
  
  
  The PROMIS, Neuro-QOL, and TBI-QOL item banks demonstrated good convergent validity, as evidenced by moderate to strong correlations with comparable scales on the legacy measures. PROMIS, Neuro-QOL, and TBI-QOL item banks showed weaker correlations with ratings of unrelated constructs on legacy measures, providing evidence of discriminant validity.
  
  
  
  Our results indicate that the constructs measured by the PROMIS, Neuro-QOL, and TBI-QOL item banks are valid in our pediatric TBI sample and that it is appropriate to use these standardized scores for our primary study analyses.
authors.affiliation: NYU Rusk Rehabilitation, New York University School of Medicine, 240 East 38th Street, Suite 17-72, New York, NY, 10016, USA. Hilary.bertisch@nyumc.org.
authors.forename: Hilary
authors.identifier: 0000-0001-5877-8737
authors.initials: H
authors.lastname: Bertisch
authors.affiliation: Departments of Pediatrics and Epidemiology, Harborview Injury Prevention and Research Center, University of Washington, Seattle Children's Research Institute, Seattle, WA, USA.
authors.forename: Frederick P
authors.initials: FP
authors.lastname: Rivara
authors.affiliation: Center on Assessment Research and Translation, Department of Physical Therapy, University of Delaware, Newark, DE, USA.
authors.forename: Pamela A
authors.initials: PA
authors.lastname: Kisala
authors.affiliation: Harborview Injury Prevention and Research Center, University of Washington, Seattle, WA, USA.
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Psychology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, USA.
authors.forename: Keith Owen
authors.initials: KO
authors.lastname: Yeates
authors.affiliation: Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Dennis
authors.initials: D
authors.lastname: Durbin
authors.affiliation: Department of Emergency Medicine, Hasbro Children's Hospital, Alpert Medical School of Brown University, Providence, RI, USA.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Zonfrillo
authors.affiliation: Critical Care Medicine, Neurological Surgery and Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Bell
authors.affiliation: Departments of Neurological Surgery and Biostatistics, University of Washington, Seattle, WA, USA.
authors.forename: Nancy
authors.initials: N
authors.lastname: Temkin
authors.affiliation: Center on Assessment Research and Translation, Departments of Physical Therapy and Psychological and Brain Sciences, University of Delaware, Newark, DE, USA.|Kessler Foundation, West Orange, NJ, USA.
authors.forename: David S
authors.initials: DS
authors.lastname: Tulsky
mesh_terms: D000293:Adolescent; D000070642:Brain Injuries, Traumatic / Q000523:psychology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009462:Neurology / Q000379:methods*; D000071066:Patient Reported Outcome Measures; D019727:Proxy; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires
keywords: Adolescent; Brain Injuries; Child; Outcome assessment (Health Care); Patient-centered outcomes research