title: The effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on longer-term maternal and early childhood outcomes: protocol for an individual participant data (IPD) meta-analysis.
abstract: The aim of this individual participant data meta-analysis (IPDMA) is to evaluate the effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood outcomes at ages 3-5 years.
  
  
  
  We will build on the established International Weight Management in Pregnancy (i-WIP) IPD Collaborative Network, having identified researchers who have conducted randomised dietary and lifestyle interventions among pregnant women who are overweight or obese, and where ongoing childhood follow-up of participants has been or is being undertaken. The primary maternal outcome is a diagnosis of maternal metabolic syndrome. The primary childhood outcome is BMI above 90%. We have identified 7 relevant trials, involving 5425 women who were overweight or obese during pregnancy, with approximately 3544 women and children with follow-up assessments available for inclusion in the meta-analysis.
  
  
  
  The proposed IPDMA provides an opportunity to evaluate the effect of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood health outcomes, including risk of obesity. This knowledge is essential to effectively translate research findings into clinical practice and public health policy.
  
  
  
  This IPD has been prospectively registered (PROSPERO), ID number CRD42016047165 .
authors.affiliation: The University of Adelaide, Discipline of Obstetrics & Gynaecology, and Robinson Research Institute, Adelaide, South Australia, Australia. jodie.dodd@adelaide.edu.au.|Department of Perinatal Medicine, Women's and Children's Hospital, 72 King William Road, North Adelaide, South Australia, 5006, Australia. jodie.dodd@adelaide.edu.au.
authors.forename: Jodie M
authors.initials: JM
authors.lastname: Dodd
authors.affiliation: The University of Adelaide, Discipline of Obstetrics & Gynaecology, and Robinson Research Institute, Adelaide, South Australia, Australia.|Department of Perinatal Medicine, Women's and Children's Hospital, 72 King William Road, North Adelaide, South Australia, 5006, Australia.
authors.forename: Rosalie M
authors.initials: RM
authors.lastname: Grivell
authors.affiliation: The University of Adelaide, Discipline of Obstetrics & Gynaecology, and Robinson Research Institute, Adelaide, South Australia, Australia.
authors.forename: Jennie
authors.initials: J
authors.lastname: Louise
authors.affiliation: The University of Adelaide, Discipline of Obstetrics & Gynaecology, and Robinson Research Institute, Adelaide, South Australia, Australia.
authors.forename: Andrea R
authors.initials: AR
authors.lastname: Deussen
authors.affiliation: The University of Adelaide, School of Public Health, Adelaide, South Australia, Australia.
authors.forename: Lynne
authors.initials: L
authors.lastname: Giles
authors.affiliation: The University of Adelaide, Discipline of Obstetrics & Gynaecology, and Robinson Research Institute, Adelaide, South Australia, Australia.
authors.forename: Ben W
authors.initials: BW
authors.lastname: Mol
authors.affiliation: Institute of Clinical Research, University of Southern Denmark, 5230, Odense M, Denmark.|Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.
authors.forename: Christina
authors.initials: C
authors.lastname: Vinter
authors.affiliation: Institute of Clinical Research, University of Southern Denmark, 5230, Odense M, Denmark.|Department of Endocrinology, Odense University Hospital, 5000, Odense C, Denmark.
authors.forename: Mette
authors.initials: M
authors.lastname: Tanvig
authors.affiliation: Department of Endocrinology, Odense University Hospital, 5000, Odense C, Denmark.
authors.forename: Dorte Moller
authors.initials: DM
authors.lastname: Jensen
authors.affiliation: Department of Healthcare Research, PHL University College, Limburg Catholic University College, Hasselt, Belgium.
authors.forename: Annick
authors.initials: A
authors.lastname: Bogaerts
authors.affiliation: Division of Mother and Child, Department of Obstetrics and Gynaecology, University Hospitals KU Leuven, Leuven, Belgium.
authors.forename: Roland
authors.initials: R
authors.lastname: Devlieger
authors.affiliation: UKK Institute for Health Promotion, Tampere, Finland.
authors.forename: Riitta
authors.initials: R
authors.lastname: Luoto
authors.affiliation: School of Medicine and Medical Science, UCD Institute of Food and Health, Dublin, Ireland.
authors.forename: Fionnuala
authors.initials: F
authors.lastname: McAuliffe
authors.affiliation: Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
authors.forename: Kristina
authors.initials: K
authors.lastname: Renault
authors.affiliation: Department of Obstetrics and Gynaecology, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
authors.forename: Emma
authors.initials: E
authors.lastname: Carlsen
authors.affiliation: Herlev and Gentofte Hospital Clinical Nutrition Research Unit, Copenhagen University Herlev, Herlev, Denmark.
authors.forename: Nina
authors.initials: N
authors.lastname: Geiker
authors.affiliation: Division of Women's Health, Women's Health Academic Centre, King's College London, St. Thomas' Hospital, London, UK.
authors.forename: Lucilla
authors.initials: L
authors.lastname: Poston
authors.affiliation: Division of Women's Health, Women's Health Academic Centre, King's College London, St. Thomas' Hospital, London, UK.
authors.forename: Annette
authors.initials: A
authors.lastname: Briley
authors.affiliation: Multidisciplinary Evidence Synthesis Hub (mEsh), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.|Women's Health Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
authors.forename: Shakila
authors.initials: S
authors.lastname: Thangaratinam
authors.affiliation: Multidisciplinary Evidence Synthesis Hub (mEsh), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.|Women's Health Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Rogozinska
authors.affiliation: The University of Adelaide, Discipline of Obstetrics & Gynaecology, and Robinson Research Institute, Adelaide, South Australia, Australia.
authors.forename: Julie A
authors.initials: JA
authors.lastname: Owens
mesh_terms: D004032:Diet; D005260:Female; D006801:Humans; D008019:Life Style; D000068097:Maternal Health; D009765:Obesity / Q000628:therapy; D063766:Pediatric Obesity; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011256:Pregnancy Outcome; D000078202:Systematic Reviews as Topic
keywords: Childhood obesity; Individual participant data meta-analysis; Pregnancy lifestyle intervention