title: Metal-free benzannulation of 1,7-diynes towards unexpected 1-aroyl-2-naphthaldehydes and their application in fused aza-heterocyclic synthesis.
abstract: A novel I2-mediated benzannulation of 1,7-diyne-involved 1,4-oxo-migration was established, providing a range of unexpected 1-aroyl-2-naphthaldehydes with a 1,4-dicarbonyl unit. The resulting 1-aroyl-2-naphthaldehydes were successfully applied in the synthesis of benzo[e]isoindol-3-ones and benzo[e]benzo[4,5]imidazo[2,1-a]isoindoles using aromatic amines and benzene-1,2-diamines as nucleophiles, respectively. The mechanisms for the formation of these compounds were proposed.
authors.affiliation: School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China. wjhao@jsnu.edu.cn laotu@jsnu.edu.cn jiangchem@jsnu.edu.cn.
authors.forename: Ai-Fang
authors.initials: AF
authors.lastname: Wang
authors.affiliation: School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China. wjhao@jsnu.edu.cn laotu@jsnu.edu.cn jiangchem@jsnu.edu.cn.
authors.forename: Peng
authors.initials: P
authors.lastname: Zhou
authors.affiliation: School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China. wjhao@jsnu.edu.cn laotu@jsnu.edu.cn jiangchem@jsnu.edu.cn.
authors.forename: Yi-Long
authors.initials: YL
authors.lastname: Zhu
authors.affiliation: School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China. wjhao@jsnu.edu.cn laotu@jsnu.edu.cn jiangchem@jsnu.edu.cn.
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Hao
authors.affiliation: Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, USA.
authors.forename: Guigen
authors.identifier: http://orcid.org/0000-0002-9312-412X
authors.initials: G
authors.lastname: Li
authors.affiliation: School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China. wjhao@jsnu.edu.cn laotu@jsnu.edu.cn jiangchem@jsnu.edu.cn.
authors.forename: Shu-Jiang
authors.initials: SJ
authors.lastname: Tu
authors.affiliation: School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China. wjhao@jsnu.edu.cn laotu@jsnu.edu.cn jiangchem@jsnu.edu.cn.
authors.forename: Bo
authors.identifier: http://orcid.org/0000-0003-3878-515X
authors.initials: B
authors.lastname: Jiang