title: Molecular and Cellular Interactions between Mother and Fetus. Pregnancy as a Rejuvenating Factor.
abstract: Aging is associated with a decline of various body functions, including ability to regenerate. Over recent decades, it has been demonstrated that some of these changes could be reversed in response to factors originating from a young organism, for example, fetal stem cells or "young blood" in models of heterochronic parabiosis. Pregnancy might be considered as parabiotic model of the interaction between two organisms of different age. In this work, we analyzed and summarized data on the effects of pregnancy on the maternal organism that confirm the hypothesis that pregnancy rejuvenates the mother's organism or slows its aging.
authors.affiliation: Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology, Moscow, 119991, Russia. zorov@genebee.msu.su.
authors.forename: V A
authors.initials: VA
authors.lastname: Popkov
authors.forename: D N
authors.initials: DN
authors.lastname: Silachev
authors.forename: S S
authors.initials: SS
authors.lastname: Jankauskas
authors.forename: L D
authors.initials: LD
authors.lastname: Zorova
authors.forename: I B
authors.initials: IB
authors.lastname: Pevzner
authors.forename: V A
authors.initials: VA
authors.lastname: Babenko
authors.forename: E Y
authors.initials: EY
authors.lastname: Plotnikov
authors.forename: D B
authors.initials: DB
authors.lastname: Zorov
mesh_terms: D000375:Aging; D000818:Animals; D005260:Female; D005333:Fetus / Q000502:physiology; D006801:Humans; D008136:Longevity; D008431:Maternal-Fetal Exchange; D009035:Mothers; D011247:Pregnancy / Q000502:physiology*; D012038:Regeneration; D012060:Rejuvenation