title: Chemical Insights into Antibacterial N-Halamines.
abstract: Microbial contamination arising from pathogens poses serious threats to human health and in recent decades has presented an unprecedented challenge to antibacterial research. Of the various antibacterial agents that effectively kill pathogens, halogen-based antibacterial compounds have been successful in eliminating harmful pathogen-associated diseases and are becoming the most popular disinfectants. As a significant subcategory of halogen antibacterial agents, N-halamines have drawn increasing research interest into their chemistry and practical applications. N-Halamines have many advantages over other antibacterial agents, including effectiveness against a broad spectrum of microorganisms, long-term physicochemical stability, high structural durability, and the regenerability of their functional groups, with corresponding renewal of their antibacterial properties. This review examines recent progress and research trends in both theoretical and experimental studies of N-halamines, with the aim of providing a systematic and comprehensive survey and assessment of the significant advances in our understanding of antibacterial N-halamines. This review serves as a practical guide to developing N-halamines through both broad and in-depth basic research and offers suggestions for their potential future applications.
authors.affiliation: College of Chemistry and Chemical Engineering, Inner Mongolia University , Hohhot 010021, People's Republic of China.
authors.forename: Alideertu
authors.identifier: http://orcid.org/0000-0002-2812-3649
authors.initials: A
authors.lastname: Dong
authors.affiliation: Department of Chemical and Biological Engineering, University of British Columbia , 2360 East Mall, Vancouver, BC, Canada V6T 1Z3.
authors.forename: Yan-Jie
authors.initials: YJ
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Inner Mongolia University , Hohhot 010021, People's Republic of China.
authors.forename: Yangyang
authors.initials: Y
authors.lastname: Gao
authors.affiliation: College of Chemistry and Chemical Engineering, Inner Mongolia University , Hohhot 010021, People's Republic of China.
authors.forename: Tianyi
authors.initials: T
authors.lastname: Gao
authors.affiliation: College of Chemistry, Jilin University , Changchun 130021, People's Republic of China.
authors.forename: Ge
authors.initials: G
authors.lastname: Gao
mesh_terms: D000588:Amines / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D006219:Halogens / Q000737:chemistry*
chemical_list: D000588:Amines; D000900:Anti-Bacterial Agents; D006219:Halogens