title: Beyond Digestion: The Pancreas Shapes Intestinal Microbiota and Immunity.
abstract: Our understanding of the regulatory mechanisms that shape the gut microbiota is rapidly emerging. The intestinal microbial landscape is modulated by a plethora of host-extrinsic and host-intrinsic factors. In this issue of Cell Metabolism, Ahuja and colleagues (2017) demonstrate that mediators secreted by pancreatic acini shape the intestinal microbiota and intestinal immunity.
authors.affiliation: Department of Internal Medicine I, Gastroenterology, Hepatology, & Endocrinology, Medical University Innsbruck, Innsbruck 6020, Austria.
authors.forename: Herbert
authors.initials: H
authors.lastname: Tilg
authors.affiliation: Department of Internal Medicine I, Gastroenterology, Hepatology, & Endocrinology, Medical University Innsbruck, Innsbruck 6020, Austria. Electronic address: herbert.tilg@i-med.ac.at.
authors.forename: Timon E
authors.initials: TE
authors.lastname: Adolph
mesh_terms: D000069196:Gastrointestinal Microbiome; D007109:Immunity; D007422:Intestines / Q000276:immunology; D064307:Microbiota; D010179:Pancreas