title: Dynamic Nuclear Polarization of β-Cyclodextrin Macromolecules.
abstract: 1H dynamic nuclear polarization and nuclear spin-lattice relaxation rates have been studied in amorphous complexes of β-cyclodextrins doped with different concentrations of the TEMPO radical. Nuclear polarization increased up to 10% in the optimal case, with a behavior of the buildup rate (1/TPOL) and of the nuclear spin-lattice relaxation rate (1/T1n) consistent with a thermal mixing regime. The temperature dependence of 1/T1nand its increase with the radical concentration indicate a relaxation process arising from the modulation of the electron-nucleus coupling by the glassy dynamics. The high-temperature relaxation is driven by molecular motions, and 1/T1nwas studied at room temperature in liquid solutions for dilution levels close to the ones typically used for in vivo studies.
authors.affiliation: Department of Physics, University of Pavia , Via Bassi 6, 27100 Pavia, Italy.
authors.forename: Filippo
authors.identifier: 0000-0003-0416-1461
authors.initials: F
authors.lastname: Caracciolo
authors.affiliation: Department of Physics, University of Pavia , Via Bassi 6, 27100 Pavia, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Carretta
authors.affiliation: Department of Physics, University of Pavia , Via Bassi 6, 27100 Pavia, Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Filibian
authors.affiliation: Department of Chemistry, Materials, and Chemical Engineering G. Natta, Politecnico of Milano , Piazza Leonardo da Vinci 32, 20133 Milano, Italy.|E-campus University , Via Isimbardi 10, 22060 Novedrate, Como, Italy.
authors.forename: Lucio
authors.initials: L
authors.lastname: Melone