title: Upper gastrointestinal endoscopy in emergency setting for patients receiving oral anticoagulants - practice updates.
abstract: Anticoagulants are frequently used medications in diverse cardiovascular diseases. Their uses highly increase the risk of bleeding from upper and lower gastrointestinal sources, whether there is a classic vitamin K antagonist or a novel oral anticoagulant. Their interruption can promote procoagulation status with different thromboembolic accidents. Discontinuation of oral anticoagulants before the elective procedures is standardized but there are no guidelines for managing bleeding lesions of upper gastrointestinal tract concomitant with anticoagulation. Also, because some of the anticoagulants are new comers, there is no specific antidote, and so their anticoagulation effect cannot be antagonized fast in order to reduce the bleeding. Therefore, the endoscopic hemostasis must be definitive and efficient. This is a short review of the current management for the bleeding lesions of the upper gastrointestinal tract in patients taking oral anticoagulants.
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: R
authors.initials: R
authors.lastname: Oprita
authors.affiliation: Clinical Emergency Hospital of Bucharest, Bucharest, Romania.
authors.forename: B
authors.initials: B
authors.lastname: Oprita
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: B
authors.initials: B
authors.lastname: Diaconescu
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: M R
authors.initials: MR
authors.lastname: Bratu
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: D
authors.initials: D
authors.lastname: Berceanu
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage* / Q000627:therapeutic use*; D004636:Emergency Service, Hospital; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D010818:Practice Patterns, Physicians'; D012307:Risk Factors
chemical_list: D000925:Anticoagulants
keywords: anticoagulant; bleeding; emergency; endoscopy; update