title: Cancer burden in slovenia with the time trends analysis.
abstract: BACKGROUND
  The aim of our study was to describe cancer burden and time trends of all cancers combined, the most frequent as well as the rare cancers in Slovenia.
  
  
  METHODS
  The principal data source was the population-based Cancer Registry of Republic of Slovenia. The cancer burden is presented by incidence and prevalence for the period 1950-2013 and by mortality for years 1985-2013. The time trends were characterized in terms of an average annual percent change estimated by the log-linear joinpoint regression. The Dyba-Hakulinen method was used for estimation of incidence in 2016 and the projections of cancer incidence for the year 2025 were calculated applying the Globocan projection software.
  
  
  RESULTS
  In recent years, near 14,000 Slovenes were diagnosed with cancer per year and just over 6,000 died; more than 94,000 people who were ever diagnosed with cancer are currently living among us. The total burden of cancer is dominated by five most common cancer sites: skin (non-melanoma), colon and rectum, lung, breast and prostate, together representing almost 60% of all new cancer cases. On average the incidence of common cancers in Slovenia is increasing for 3.0% per year in last decade, but the incidence of rare cancers is stable.
  
  
  CONCLUSIONS
  Because cancer occurs more among the elderly, and additionally more numerous post-war generation is entering this age group, it is expected that the burden of this disease will be growing further, even if the level of risk factors remains the same as today.
authors.affiliation: Institute of Oncology Ljubljana, Epidemiology and Cancer Registry, Ljubljana, Slovenia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Zadnik
authors.affiliation: Institute of Oncology Ljubljana, Epidemiology and Cancer Registry, Ljubljana, Slovenia.
authors.forename: Maja
authors.initials: M
authors.lastname: Primic Zakelj
authors.affiliation: Institute of Oncology Ljubljana, Epidemiology and Cancer Registry, Ljubljana, Slovenia.
authors.forename: Katarina
authors.initials: K
authors.lastname: Lokar
authors.affiliation: Institute of Oncology Ljubljana, Epidemiology and Cancer Registry, Ljubljana, Slovenia.
authors.forename: Katja
authors.initials: K
authors.lastname: Jarm
authors.affiliation: Institute of Oncology Ljubljana, Epidemiology and Cancer Registry, Ljubljana, Slovenia.
authors.forename: Urska
authors.initials: U
authors.lastname: Ivanus
authors.affiliation: Institute of Oncology Ljubljana, Epidemiology and Cancer Registry, Ljubljana, Slovenia.
authors.forename: Tina
authors.initials: T
authors.lastname: Zagar
keywords: Cancer Registry of Republic of Slovenia; cancer burden; cancer incidence; time trend