title: A New Strategy for Transcatheter Left Atrial Appendage Closure With Cerebral Embolic Protection in Patient With Left Auricular Thrombosis and Total Contraindication to Long-Term Anticoagulation.
abstract: Atrial fibrillation (AF) is the most common cardiac arrhythmia, occurring in 1%-2% of the general population. An important aspect is the treatment of AF in terms of stroke prevention. In patients with absolute contraindication to long-term anticoagulation due to high bleeding risk, a valuable alternative exists in left atrial appendage (LAA) closure. Unfortunately, thrombus in the LAA is a contraindication to the procedure because of high risk of embolization. We describe a clinical case with permanent AF, absolute contraindication to long-term anticoagulation therapy, and persistent thrombus formation in the LAA that was treated with transcatheter LAA closure and supraaortic trunk protection system in order to avoid risk of periprocedural stroke.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Saccà
authors.affiliation: Cardiology Department, Mirano General Hospital, via Mariutto 13, Mirano, Venice, Italy. jayme.ferro@gmail.com.
authors.forename: Jayme
authors.initials: J
authors.lastname: Ferro
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Umemoto
authors.forename: Riccardo
authors.initials: R
authors.lastname: Turri
authors.forename: Carlo
authors.initials: C
authors.lastname: Penzo
authors.forename: Andrea
authors.initials: A
authors.lastname: Pacchioni
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D020517:Atrial Appendage / Q000000981:diagnostic imaging / Q000601:surgery; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy; D006328:Cardiac Catheterization / Q000379:methods; D017548:Echocardiography, Transesophageal / Q000379:methods; D006331:Heart Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D006470:Hemorrhage / Q000139:chemically induced / Q000517:prevention & control*; D006801:Humans; D020766:Intracranial Embolism / Q000209:etiology / Q000517:prevention & control; D008297:Male; D020379:Risk Adjustment / Q000379:methods; D055989:Septal Occluder Device; D013927:Thrombosis / Q000150:complications / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants