title: Collagen-Based Photoactive Agent for Tissue Bonding.
abstract: Using a combination of methacrylated collagen and the photosensitizer rose Bengal, a new light-activated biomimetic material for tissue sutureless bonding was developed. This formulation was cross-linked using green light. In vivo tests in mice demonstrate the suitability of the material for sutureless wound closure.
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.|Department of Clinical and Experimental Medicine, Linköping University , Linköping, Sweden.
authors.forename: Justina
authors.initials: J
authors.lastname: Pupkaite
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.
authors.forename: Manuel
authors.initials: M
authors.lastname: Ahumada
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.
authors.forename: Sarah
authors.initials: S
authors.lastname: Mclaughlin
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.
authors.forename: Maha
authors.initials: M
authors.lastname: Temkit
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.
authors.forename: Sura
authors.initials: S
authors.lastname: Alaziz
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.
authors.forename: Richard
authors.initials: R
authors.lastname: Seymour
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.
authors.forename: Marc
authors.initials: M
authors.lastname: Ruel
authors.affiliation: Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School , Boston, United States.
authors.forename: Irene
authors.initials: I
authors.lastname: Kochevar
authors.affiliation: Department of Clinical and Experimental Medicine, Linköping University , Linköping, Sweden.
authors.forename: May
authors.initials: M
authors.lastname: Griffith
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Suuronen
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, Canada.|Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa , Ottawa, Canada.
authors.forename: Emilio I
authors.identifier: http://orcid.org/0000-0001-5100-6179
authors.initials: EI
authors.lastname: Alarcon
mesh_terms: D000818:Animals; D003094:Collagen / Q000737:chemistry*; D003432:Cross-Linking Reagents; D051379:Mice; D017319:Photosensitizing Agents; D012395:Rose Bengal
chemical_list: D003432:Cross-Linking Reagents; D017319:Photosensitizing Agents; D012395:Rose Bengal; D003094:Collagen
keywords: collagen; cross-linking; rose Bengal; tissue photobonding; wound healing