title: A formal homo-Nazarov cyclization of enantioenriched donor-acceptor cyclopropanes and following transformations: asymmetric synthesis of multi-substituted dihydronaphthalenes.
abstract: Multi-substituted trans-dihydronaphthalenes were obtained in high enantiomeric excess from a TiCl4-mediated cyclization of enantioenriched donor-acceptor cyclopropanes, followed by a triflation of the hydroxy groups. The C-OTf bond in these multi-substituted trans-dihydronaphthalenes is susceptible to further Pd-catalyzed hydrogenations and coupling reactions, which afforded the corresponding C-H or C-C bonded products.
authors.affiliation: Department of Applied Chemistry, Faculty of Textile Science and Technology, Shinshu University, Tokida 3-15-1, Uea, Nagano 386-8567, Japan. nishii@shinshu-u.ac.jp.
authors.forename: Seijiro
authors.initials: S
authors.lastname: Takada
authors.forename: Naoya
authors.initials: N
authors.lastname: Takaki
authors.forename: Kenta
authors.initials: K
authors.lastname: Yamada
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nishii