title: The Role of Radionuclide Imaging in Epilepsy, Part 2: Epilepsy Syndromes.
abstract: PET and SPECT can play an important role in the evaluation of various epileptic syndromes, particularly those with unknown causes, by revealing various underlying abnormalities that may not be fully appreciated from MR imaging studies. In some cases, PET and SPECT provide crucial data that guide surgical resections of the epileptogenic zone for medically refractory epilepsy. In other cases, these neuroimaging modalities preclude a surgical option and can guide genetic studies. Longitudinal PET and SPECT studies may increase our understanding of the etiopathogenesis of epilepsy syndromes and provide a clearer picture of the natural history of neurologic progression.
authors.affiliation: PET Center, Department of Pediatrics, Neurology, and Radiology, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University School of Medicine, Detroit, Michigan ajay@pet.wayne.edu.
authors.forename: Ajay
authors.initials: A
authors.lastname: Kumar
authors.affiliation: PET Center, Department of Pediatrics, Neurology, and Radiology, Children's Hospital of Michigan, Detroit Medical Center, Wayne State University School of Medicine, Detroit, Michigan.
authors.forename: Harry T
authors.initials: HT
authors.lastname: Chugani
mesh_terms: D004827:Epilepsy / Q000150:complications* / Q000000981:diagnostic imaging*; D006801:Humans; D049268:Positron-Emission Tomography / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
keywords: FDG; PET; SPECT; epilepsy; epilepsy surgery; epilepsy syndromes; radionuclide; seizure