title: Ruthenium nitrosyl functionalized graphene quantum dots as an efficient nanoplatform for NIR-light-controlled and mitochondria-targeted delivery of nitric oxide combined with photothermal therapy.
abstract: A mitochondria-targeting nanoplatform for near-infrared-light-controlled release of nitric oxide accompanied by photothermal therapy was developed, which consists of ruthenium nitrosyl functionalized N-doped graphene quantum dots and a triphenylphosphonium moiety. The nanoplatform demonstrated both in vitro and in vivo anti-tumor efficacy upon irradiation with 808 nm light.
authors.affiliation: Key Lab for Advanced Materials of MOE, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China. liujingang@ecust.edu.cn.
authors.forename: Min
authors.initials: M
authors.lastname: Guo
authors.forename: Hui-Jing
authors.initials: HJ
authors.lastname: Xiang
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.forename: Qian-Ling
authors.initials: QL
authors.lastname: Zhang
authors.forename: Lu
authors.initials: L
authors.lastname: An
authors.forename: Shi-Ping
authors.initials: SP
authors.lastname: Yang
authors.forename: Yinchu
authors.initials: Y
authors.lastname: Ma
authors.forename: Yucai
authors.initials: Y
authors.lastname: Wang
authors.forename: Jin-Gang
authors.initials: JG
authors.lastname: Liu