title: Topological-Pattern-Based Recommendation of UMLS Concepts for National Cancer Institute Thesaurus.
abstract: The National Cancer Institute Thesaurus (NCIt) is a reference terminology used to support clinical, translational and basic research as well as administrative activities. As medical knowledge evolves, concepts that might be missing from a particular needed subdomain are regularly added to the NCIt. However, terminology development is known to be labor-intensive and error-prone. Therefore, cost-effective semi-automated methods for identifying potentially missing concepts would be useful to terminology curators. Previously, we have developed a structural method leveraging the native term mappings of the Unified Medical Language System to identify potential concepts in several of its source vocabularies to enrich the SNOMED CT. In this paper, we tested an analogous method for NCIt. Concepts from eight UMLS source terminologies were identified as possibilities to enrich NCIt's conceptual content.
authors.affiliation: School of Information, Florida State University, Tallahassee, FL; Institute for Successful Longevity, Florida State University, Tallahassee, FL.
authors.forename: Zhe
authors.initials: Z
authors.lastname: He
authors.affiliation: Department of Computer Information Systems, Borough of Manhattan Community College, City University of New York, New York, NY.
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.affiliation: National Cancer Institute, Rockville, MD.
authors.forename: Sherri
authors.initials: S
authors.lastname: de Coronado
authors.affiliation: Weill Cornell Medicine, New York, NY.
authors.forename: Katrina
authors.initials: K
authors.lastname: Piskorski
authors.affiliation: Department of Computer Science, New Jersey Institute of Technology, Newark, NJ.
authors.forename: James
authors.initials: J
authors.lastname: Geller
mesh_terms: D006801:Humans; D054547:National Cancer Institute (U.S.); D009369:Neoplasms; D013358:Subject Headings; D039061:Systematized Nomenclature of Medicine; D017432:Unified Medical Language System; D014481:United States; D018875:Vocabulary, Controlled