title: Feasible Relation between Glutathione Peroxidase and Febrile Seizure.
abstract: OBJECTIVE
  We aimed to determine the relationship between serum glutathione peroxidase and febrile seizure.
  
  
  METHODS
  In this case-control study, 43 children with simple febrile seizure (case group) were compared with 43 febrile children without seizure (control group) in terms of serum glutathione peroxidase level, measured by ELISA method. This study was conducted in Qazvin Children Hospital, Qazvin University of Medical Sciences in Qazvin, Iran in 2012-2013. The results were analyzed and compared in two groups.
  
  
  RESULTS
  From 43 children 24 (53%) were male and 19 (47%) were female in children with simple febrile seizure, and 26 (60%) were male and 17 (40%) were female in febrile children without seizure (control group) (P=0.827). Serum glutathione peroxidase level was 166 U/ml (SD=107) in the case group and 141 U/ml (SD=90.5) in the control group of no significant difference.
  
  
  CONCLUSIONS
  There was no significant relationship between serum glutathione peroxidase and simple febrile seizure. Thus, it seems that glutathione peroxidase, an essential component of antioxidant system, does not play any role in the pathogenesis of simple febrile seizure.
authors.affiliation: Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Mahyar
authors.affiliation: Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Parviz
authors.initials: P
authors.lastname: Ayazi
authors.affiliation: Pediatric Nephrology Department Mofid children hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Dalirani
authors.affiliation: Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Mohammad Hoseini
authors.affiliation: Cell and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Sarookhani
authors.affiliation: Department of Statistics, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Amir
authors.initials: A
authors.lastname: Javadi
authors.affiliation: Department of Statistics, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Shiva
authors.initials: S
authors.lastname: Esmaeily
keywords: Febrile Seizure; Glutathione Peroxidase