title: Atrial fibrillation in transcatheter aortic valve implantation patients: Incidence, outcome and predictors of new onset.
abstract: There is controversial evidence if atrial fibrillation (AF) alters outcome after transcatheter aortic valve implantation (TAVI). TAVI itself may promote new-onset AF (NOAF).
  
  
  
  We performed a single-center study including 398 consecutive patients undergoing TAVI. Before TAVI, patients were divided into a sinus rhythm (SR) group (n=226, 57%) and baseline AF group (n=172, 43%) according to clinical records and electrocardiograms. Furthermore, incidence and predictors of NOAF were recorded.
  
  
  
  Baseline AF patients had a significantly higher 1-year mortality than the baseline SR group (19.8% vs. 11.5%, p=0.02). NOAF occurred in 7.1% of patients with prior SR. Previous valve surgery was the only significant predictor of NOAF (HR 5.86 [1.04-32.94], p<0.05). NOAF was associated with higher rehospitalization rate (62.5 vs. 34.8%, p=0.04), whereas mortality was unaffected.
  
  
  
  This study shows that NOAF is associated with higher rates of rehospitalization but not mortality after TAVI. Overall, patients with pre-existing AF have higher mortality.
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria. Electronic address: david.zweiker@medunigraz.at.
authors.forename: David
authors.initials: D
authors.lastname: Zweiker
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Mario
authors.initials: M
authors.lastname: Fröschl
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Tiede
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Paul
authors.initials: P
authors.lastname: Weidinger
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Johannes
authors.initials: J
authors.lastname: Schmid
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Martin
authors.initials: M
authors.lastname: Manninger
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Helmut
authors.initials: H
authors.lastname: Brussee
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Robert
authors.initials: R
authors.lastname: Zweiker
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Josepha
authors.initials: J
authors.lastname: Binder
authors.affiliation: Department of Heart Surgery, Medical University of Graz, Graz, Austria.
authors.forename: Heinrich
authors.initials: H
authors.lastname: Mächler
authors.affiliation: Department of Anaesthesiology, Medical University of Graz, Graz, Austria.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Marte
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Robert
authors.initials: R
authors.lastname: Maier
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Olev
authors.initials: O
authors.lastname: Luha
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Albrecht
authors.initials: A
authors.lastname: Schmidt
authors.affiliation: Division of Cardiology, Medical University of Graz, Graz, Austria.
authors.forename: Daniel
authors.initials: D
authors.lastname: Scherr
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000453:epidemiology* / Q000401:mortality; D001317:Austria / Q000453:epidemiology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D010359:Patient Readmission / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000453:epidemiology* / Q000401:mortality; D012307:Risk Factors; D065467:Transcatheter Aortic Valve Replacement; D016896:Treatment Outcome
keywords: Atrial fibrillation; New-onset AF; One-year mortality; Retrospective study; Transcatheter aortic valve implantation