title: Aquaporins in Fetal Development.
abstract: Water homeostasis during fetal development is of crucial physiologic importance. The successful formation and development of the placenta is critical to maintain normal fetal growth and homeostasis. The expression of several aquaporins (AQPs ) was found from blastocyst stages to term placenta and fetal membranes. Therefore, AQPs are proposed to play important roles in normal pregnancy, fetal growth, and homeostasis of amniotic fluid volume, and water handling in other organs. However, the functional importance of AQPs in fetal development remains to be elucidated.
authors.affiliation: Laboratorio de Biología de la Reproducción, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO)- CONICET- Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Nora
authors.initials: N
authors.lastname: Martínez
authors.affiliation: Laboratorio de Biología de la Reproducción, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO)- CONICET- Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina. adamiano@ffyb.uba.ar.|Cátedra de Biología Celular y Molecular, Departamento de Ciencias Biológicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 1er piso, CP 1113, Buenos Aires, Argentina. adamiano@ffyb.uba.ar.
authors.forename: Alicia E
authors.initials: AE
authors.lastname: Damiano
mesh_terms: D000653:Amniotic Fluid / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D051398:Aquaporin 1 / Q000235:genetics / Q000378:metabolism*; D001755:Blastocyst / Q000378:metabolism*; D006063:Chorionic Gonadotropin / Q000235:genetics / Q000378:metabolism; D005321:Extraembryonic Membranes / Q000254:growth & development / Q000378:metabolism*; D005260:Female; D047109:Fetal Development / Q000502:physiology*; D005333:Fetus; D005786:Gene Expression Regulation; D006801:Humans; D007328:Insulin / Q000235:genetics / Q000378:metabolism; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D020033:Protein Isoforms / Q000235:genetics / Q000378:metabolism; D014867:Water / Q000378:metabolism*
chemical_list: C496020:AQP1 protein, human; D006063:Chorionic Gonadotropin; D007328:Insulin; D020033:Protein Isoforms; D014867:Water; D051398:Aquaporin 1
keywords: Aquaporin; Fetal development; Water; Water channel