title: [Specific features of joint ultrasound study in patients with rheumatoid arthritis].
abstract: OBJECTIVE
  To study the specific features of joint ultrasound readings in rheumatoid arthritis (RA) in relation to its duration.
  
  
  METHODS
  A total of 162 patients (mean age, 43.54±11.1 years) with a mean RA duration of 3.22±3.13 years were examined. Gray-scale ultrasound study (USS) of hand and ankle joints was performed using color Doppler energy imaging. Group 1 included 78 patients with a RA duration of less than 2 years; Group 2 consisted of 84 patients with a RA duration of more than 2 years.
  
  
  RESULTS
  Joint USS diagnosed osteochondral erosions twice more frequently than conventional radiography. 82% of the patients with RA were found to have synovitis; 77% had thickening of the synovial membrane (SM) with hypervascularization, the vascularization intensity scores of 2-3 being predominant; and 54% had tenosynovitis of the carpal extensor tendon. Effusion into the joint cavity, SM hypervascularization scores of 2-3, and tenosynovitis were most common in Group 1. SM thickening and osteochondral erosions were prevalent in Group 2.
  
  
  CONCLUSIONS
  Joint USS revealed that angiogenesis and inflammation were dominant in the patients with a RA duration of less than 2 years and the proliferative-destructive processes were prevalent in those with a RA duration of more than 2 years. Identifying the predominance of pathophysiological processes in each specific patient with RA will be able to individualize therapy and to improve the prognosis of the disease.
authors.affiliation: GU 'Luganskij gosudarstvennyj meditsinskij universitet', Lugansk, LNR.
authors.forename: E B
authors.initials: EB
authors.lastname: Komarova
authors.affiliation: GU 'Luganskij gosudarstvennyj meditsinskij universitet', Lugansk, LNR.
authors.forename: O A
authors.initials: OA
authors.lastname: Rebrova
authors.affiliation: Luganskaja respublikanskaja klinicheskaja bol'nitsa, Lugansk, LNR.
authors.forename: I I
authors.initials: II
authors.lastname: Pokrushka
authors.affiliation: Luganskaja respublikanskaja klinicheskaja bol'nitsa, Lugansk, LNR.
authors.forename: Yu G
authors.initials: YG
authors.lastname: Kindritskaya
mesh_terms: D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color / Q000379:methods*