title: Preoperative predictive factors for gallbladder cholesterol polyp diagnosed after laparoscopic cholecystectomy for polypoid lesions of gallbladder.
abstract: OBJECTIVE
  We investigated patients' clinical and radiological data to determine preoperative factors that predict cholesterol gallbladder (GB) polyps of large size, which can be helpful for decision on further diagnostic tools.
  
  
  METHODS
  In this study, we retrospectively analyzed 126 patients who underwent laparoscopic cholecystectomy for GB polyps >10 mm diagnosed preoperatively by abdominal ultrasonography between February 2002 and February 2016 in Department of Surgery, Sanggye Paik Hospital. Patients were divided into non-cholesterol polyps group and cholesterol polyps group, based on the postoperative pathologic diagnosis. Clinical and radiological data, such as gender, age, body weight, height, body mass index (BMI), laboratory findings, size, number and shape of the polypoid lesions, and presence of the concurrent GB stone were compared between the two groups.
  
  
  RESULTS
  Of the 126 cases, 73 had cholesterol polyps (57.9%) and 53 cases were non-cholesterol polyps (42.1%). The younger age (<48.5 years), size of polyp <13.25 mm and multiple polyps were independent predictive variables for cholesterol polyps, with odd ratios (OR) of 2.352 (p=0.045), 5.429 (p<0.001) and 0.472 (p<0.001), respectively.
  
  
  CONCLUSIONS
  Age, size and polyp number were used to predict cholesterol GB polyp among polypoid lesions of the gallbladder >10 mm. For cases in which these factors are not applicable, it is strongly recommended to evaluate further diagnostic tools, such as computed tomography, endoscopic ultrasonography and tumor markers.
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Hyojin
authors.initials: H
authors.lastname: Lee
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Kihwan
authors.initials: K
authors.lastname: Kim
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Inseok
authors.initials: I
authors.lastname: Park
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Hyunjin
authors.initials: H
authors.lastname: Cho
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Geumhee
authors.initials: G
authors.lastname: Gwak
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Keunho
authors.initials: K
authors.lastname: Yang
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Byung-Noe
authors.initials: BN
authors.lastname: Bae
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Hong-Ju
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Young Duk
authors.initials: YD
authors.lastname: Kim
keywords: Cholesterol; Gallbladder; Laparoscopic cholecystectomy; Polyps