title: Early processing in primary visual cortex is necessary for conscious and unconscious vision while late processing is necessary only for conscious vision in neurologically healthy humans.
abstract: The neural mechanisms underlying conscious and unconscious visual processes remain controversial. Blindsight patients may process visual stimuli unconsciously despite their V1 lesion, promoting anatomical models, which suggest that pathways bypassing the V1 support unconscious vision. On the other hand, physiological models argue that the major geniculostriate pathway via V1 is involved in both unconscious and conscious vision, but in different time windows and in different types of neural activity. According to physiological models, feedforward activity via V1 to higher areas mediates unconscious processes whereas feedback loops of recurrent activity from higher areas back to V1 support conscious vision. With transcranial magnetic stimulation (TMS) it is possible to study the causal role of a brain region during specific time points in neurologically healthy participants. In the present study, we measured unconscious processing with redundant target effect, a phenomenon where participants respond faster to two stimuli than one even when one of the stimuli is not consciously perceived. We tested the physiological feedforward-feedback model of vision by suppressing conscious vision by interfering selectively either with early or later V1 activity with TMS. Our results show that early V1 activity (60ms) is necessary for both unconscious and conscious vision. During later processing stages (90ms), V1 contributes selectively to conscious vision. These findings support the feedforward-feedback-model of consciousness.
authors.affiliation: Department of Psychology, University of Turku, 20014 Finland; Centre for Cognitive Neuroscience, University of Turku, 20014 Finland; Turku Brain and Mind Centre, University of Turku, 20014 Finland. Electronic address: mijhur@utu.fi.
authors.forename: Mikko
authors.initials: M
authors.lastname: Hurme
authors.affiliation: Department of Psychology, University of Turku, 20014 Finland; Centre for Cognitive Neuroscience, University of Turku, 20014 Finland; Turku Brain and Mind Centre, University of Turku, 20014 Finland.
authors.forename: Mika
authors.initials: M
authors.lastname: Koivisto
authors.affiliation: Department of Psychology, University of Turku, 20014 Finland; Centre for Cognitive Neuroscience, University of Turku, 20014 Finland; Turku Brain and Mind Centre, University of Turku, 20014 Finland; School of Bioscience, University of Skövde, 54128 Sweden.
authors.forename: Antti
authors.initials: A
authors.lastname: Revonsuo
authors.affiliation: Department of Psychology, University of Turku, 20014 Finland; Centre for Cognitive Neuroscience, University of Turku, 20014 Finland; Turku Brain and Mind Centre, University of Turku, 20014 Finland.
authors.forename: Henry
authors.initials: H
authors.lastname: Railo
mesh_terms: D000328:Adult; D003243:Consciousness / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D050781:Transcranial Magnetic Stimulation; D014474:Unconsciousness; D014793:Visual Cortex / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult
keywords: Redundant target effect; TMS; V1; unconscious vision