title: Low-cost rapid prototyping of liquid crystal polymer based magnetic microactuators for glaucoma drainage devices.
abstract: Glaucoma is one of the leading causes of blindness in the world. Although there is no cure for glaucoma, pharmaceutical or surgical interventions are known to delay the progression of this debilitating disease. In recent years, implantation of glaucoma drainage devices (GDD) have increased due to their ability to manage IOP better than other therapeutic approaches. However, only 50% of the implanted devices remain functional after 5 years often due to biofouling. Here, we report our latest progress towards developing self-clearing GDDs using integrated magnetic microactuators. Our hypothesis is that these magnetic microdevices can provide local mechanical perturbations to prophylactically remove biological accumulation. To reduce the cost and increase the throughput of fabrication, we utilize a maskless photolithography setup and commercially available liquid crystal polymer foils to create prototype devices. The mechanical response of the devices is reported and compared with the theoretical values.
authors.lastname: Hyunsu Park
authors.forename: Simon
authors.initials: S
authors.lastname: John
authors.lastname: Hyowon Lee
mesh_terms: D004322:Drainage / Q000295:instrumentation / Q000379:methods; D005901:Glaucoma / Q000517:prevention & control / Q000601:surgery; D020327:Glaucoma Drainage Implants; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008280:Magnetics; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers; C422409:liquid crystal polymer