title: Development and Validation of the Korean Version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Patients with Non-muscle Invasive Bladder Cancer: EORTC QLQ-NMIBC24.
abstract: OBJECTIVE
  We aimed to evaluate psychometric properties of the Korean version of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-NMIBC24 when applied to Korean non-muscle invasive bladder cancer (NMIBC) patients.
  
  
  METHODS
  A total of 249 patients who underwent curative transurethral resection of bladder tumor (TURBT) for primary or recurrent NMIBC were asked to complete the Korean version of EORTC QLQ-C30 and -NMIBC24 questionnaires three times (preoperative, post-TURBT 3 months and 6 months). Linguistic validation and psychometric evaluation of the questionnaire was conducted.
  
  
  RESULTS
  Multitrait scaling analysis confirmed satisfactory construct validity in five scales except the malaise scale. Internal consistency was good (Cronbach's alpha ≥ 0.70) for the five scales except the malaise scale at the all three time points. Known-group comparison analyses showed better quality-of-life (QOL) scores in patients with higher performance status as expected, and better sexual function in men than women (p < 0.05). Most of the scales had low correlations (< 0.40) with the scales in QLQ-C30 showing divergent validity, except for malaise scale which showed higher correlations (0.42 to 0.60). Responsiveness to change was consistent with clinical implications over time after TURBT.
  
  
  CONCLUSIONS
  The Korean version of the EORTC QLQ-NMIBC24 has good reliability and cross-cultural validity for measuring various QOL aspects that can be self-administered to Korean NMIBC patients undergoing TURBT.
authors.affiliation: Department of Urology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
authors.forename: Jinsung
authors.initials: J
authors.lastname: Park
authors.affiliation: Department of Family Medicine, Seoul National University Hospital, Seoul, Korea.
authors.forename: Dong Wook
authors.initials: DW
authors.lastname: Shin
authors.affiliation: Department of Urology, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Tae-Hwan
authors.initials: TH
authors.lastname: Kim
authors.affiliation: Department of Urology, Chonnam National University Medical School, Gwangju, Korea.
authors.forename: Seung Il
authors.initials: SI
authors.lastname: Jung
authors.affiliation: Department of Urology, Pusan National University Yangsan Hospital, Yangsan, Korea.
authors.forename: Jong Kil
authors.initials: JK
authors.lastname: Nam
authors.affiliation: Department of Urology, Wonkwang University School of Medicine, Iksan, Korea.
authors.forename: Seung Chol
authors.initials: SC
authors.lastname: Park
authors.affiliation: Department of Urology, Dankook University College of Medicine, Cheonan, Korea.
authors.forename: Sungwoo
authors.initials: S
authors.lastname: Hong
authors.affiliation: Department of Urology, Yonsei University Wonju College of Medicine, Wonju, Korea.
authors.forename: Jae Hung
authors.initials: JH
authors.lastname: Jung
authors.affiliation: Department of Urology, Konyang University College of Medicine, Daejeon, Korea.
authors.forename: Hongwook
authors.initials: H
authors.lastname: Kim
authors.affiliation: Department of Urology, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: Won Tae
authors.initials: WT
authors.lastname: Kim
mesh_terms: D000368:Aged; D005060:Europe; D005260:Female; D006801:Humans; D007723:Korea; D007802:Language; D008297:Male; D010865:Pilot Projects; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D001749:Urinary Bladder Neoplasms / Q000628:therapy*; D054928:Validation Studies as Topic
keywords: Psychometric properties; Quality of life; Surveys and questionnaire; Urinary bladder neoplasms