title: What vaccination studies tell us about immunological memory within the innate immune system of cultured shrimp and crayfish.
abstract: The possibility of immunological memory in invertebrates is a topic that has recently attracted a lot of attention. Today, even vertebrates are known to exhibit innate immune responses that show memory-like properties, and since these responses are triggered by cells that are involved in the innate immune system, it seems that immune specificity and immune memory do not necessarily require the presence of B cells and T cells after all. This kind of immune response has been called "immune priming" or "trained immunity". In this report, we review recent observations and our current understanding of immunological memory within the innate immune system in cultured shrimp and crayfish after vaccination with live vaccine, killed vaccine and subunit vaccines. We also discuss the possible mechanisms involved in this immune response.
authors.affiliation: Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC.
authors.forename: Yu-Hsuan
authors.initials: YH
authors.lastname: Chang
authors.affiliation: Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC.
authors.forename: Ramya
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC.
authors.forename: Tze Hann
authors.initials: TH
authors.lastname: Ng
authors.affiliation: Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC. Electronic address: wanghc@mail.ncku.edu.tw.
authors.forename: Han-Ching
authors.initials: HC
authors.lastname: Wang
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000235:genetics / Q000276:immunology*; D017756:Aquaculture; D001156:Artemia / Q000276:immunology*; D003400:Astacoidea / Q000276:immunology*; D007113:Immunity, Innate; D007156:Immunologic Memory; D034622:RNA Interference / Q000276:immunology*; D014611:Vaccination; D022223:Vaccines, Subunit / Q000276:immunology*; D014733:Vibrio / Q000276:immunology*; D014735:Vibrio Infections / Q000276:immunology*; D014765:Viral Vaccines / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology*; D046848:White spot syndrome virus 1 / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D022223:Vaccines, Subunit; D014765:Viral Vaccines
keywords: Crayfish; Dscam; Immune priming; Immunological memory within the innate immune system; Shrimp; Vaccination