title: Efficacy of collagen matrix seal and collagen sponge on ridge preservation in combination with bone allograft: A randomized controlled clinical trial.
abstract: OBJECTIVE
  To test whether the use of collagen matrix seal (CMS) results in similar hard and soft tissue remodelling to that with collagen sponge (CS) used as barriers 4 months following alveolar ridge preservation (ARP), in combination with freeze-dried bone allograft (FDBA).
  
  
  METHODS
  Twenty-eight patients were randomly assigned to the two groups. Clinical and radiographic measurements were recorded with the same stent at baseline and 4 months for standardization. The flapless technique following a traumatic extraction was used for the two types of barriers.
  
  
  RESULTS
  All patients completed the study, 14 in the CMS group and 14 in the CS group. Reduction in coronal ridge width (1.21 mm-14.91% CMS and 1.47 mm-20.40% CS) and vertical buccal bone resorption (0.30 mm CMS and 0.79 mm CS) were not significantly different. A slight increase in buccal gingival thickness at the coronal part was observed in both groups (0.9 mm CMS and 0.5 mm CS).
  
  
  CONCLUSIONS
  Collagen matrix seal and CS, when combined with FDBA, significantly minimized ridge resorption in all dimensions and maintained buccal soft tissue thickness in sockets with a buccal plate loss of <2 mm in comparison to previously reported findings recorded after tooth extraction without ARP.
authors.affiliation: Department of Dental Public Health, School of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.|Department of Periodontology, School of Dental Medicine, Tufts University, Boston, MA, USA.
authors.forename: Zuhair S
authors.identifier: http://orcid.org/0000-0003-2723-0255
authors.initials: ZS
authors.lastname: Natto
authors.affiliation: Department of Periodontology, School of Dental Medicine, Tufts University, Boston, MA, USA.
authors.forename: Andreas
authors.initials: A
authors.lastname: Parashis
authors.affiliation: Department of Periodontology, School of Dental Medicine, Tufts University, Boston, MA, USA.
authors.forename: Bjorn
authors.initials: B
authors.lastname: Steffensen
authors.affiliation: Department of Diagnosis and Health Promotion, School of Dental Medicine, Tufts University, Boston, MA, USA.
authors.forename: Rumpa
authors.initials: R
authors.lastname: Ganguly
authors.affiliation: Department of Public Health, School of Dental Medicine, Tufts University, Boston, MA, USA.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Finkelman
authors.affiliation: Department of Periodontology, School of Dental Medicine, Tufts University, Boston, MA, USA.
authors.forename: Y Natalie
authors.initials: YN
authors.lastname: Jeong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D064591:Allografts / Q000601:surgery; D016301:Alveolar Bone Loss / Q000628:therapy; D000539:Alveolar Process / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000601:surgery; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D016025:Bone Transplantation / Q000379:methods*; D003094:Collagen / Q000627:therapeutic use*; D015921:Dental Implants; D005260:Female; D005612:Freeze Drying; D005881:Gingiva / Q000033:anatomy & histology; D006801:Humans; D007180:Incisor; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D014081:Tooth Extraction; D020390:Tooth Socket / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*
chemical_list: D015921:Dental Implants; D008567:Membranes, Artificial; D003094:Collagen
keywords: alveolar ridge preservation; bone allograft; collagen matrix; collagen sponge; extracellular matrix; extraction socket