title: Octahedral Ruthenium Complex with Exclusive Metal-Centered Chirality for Highly Effective Asymmetric Catalysis.
abstract: A novel ruthenium catalyst is introduced which contains solely achiral ligands and acquires its chirality entirely from octahedral centrochirality. The configurationally stable catalyst is demonstrated to catalyze the alkynylation of trifluoromethyl ketones with very high enantioselectivity (up to >99% ee) at low catalyst loadings (down to 0.2 mol%).
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg , Hans-Meerwein-Strasse 4, 35043 Marburg, Germany.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg , Hans-Meerwein-Strasse 4, 35043 Marburg, Germany.
authors.forename: Yuqi
authors.initials: Y
authors.lastname: Tan
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg , Hans-Meerwein-Strasse 4, 35043 Marburg, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Harms
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg , Hans-Meerwein-Strasse 4, 35043 Marburg, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Marsch
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg , Hans-Meerwein-Strasse 4, 35043 Marburg, Germany.
authors.forename: Radostan
authors.initials: R
authors.lastname: Riedel
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg , Hans-Meerwein-Strasse 4, 35043 Marburg, Germany.
authors.forename: Lilu
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Fachbereich Chemie, Philipps-Universität Marburg , Hans-Meerwein-Strasse 4, 35043 Marburg, Germany.
authors.forename: Eric
authors.identifier: 0000-0002-8851-7623
authors.initials: E
authors.lastname: Meggers