title: Emotion processing in early blind and sighted individuals.
abstract: OBJECTIVE
  Emotion processing is known to be mediated by a complex network of cortical and subcortical regions with evidence of specialized hemispheric lateralization within the brain. In light of prior evidence indicating that lateralization of cognitive functions (such as language) may depend on normal visual development, we investigated whether the lack of prior visual experience would have an impact on the development of specialized hemispheric lateralization in emotional processing.
  
  
  METHODS
  We addressed this issue by comparing performance in early blind and sighted controls on a dichotic listening task requiring the detection of specific emotional vocalizations (i.e., suggestive of happiness or sadness) presented independently to either ear.
  
  
  RESULTS
  Consistent with previous studies, we found that sighted individuals showed enhanced detection of positive vocalizations when presented in the right ear (i.e., processed within the left hemisphere) and negative vocalizations when presented in the left ear (i.e., right hemisphere). It is interesting to note that although blind individuals were as accurate as sighted controls in detecting the valance of the vocalization, performance was not consistent with any pattern of specialized hemispheric lateralization.
  
  
  CONCLUSIONS
  Overall, these results suggest that although the lack of prior visual experience may not lead to impaired emotion processing performance, the underlying neurophysiological substrate (i.e., degree of special hemispheric lateralization) may depend on normal visual development. (PsycINFO Database Record
authors.affiliation: Department of Psychology, University of Milano-Bicocca.
authors.forename: Lucile
authors.initials: L
authors.lastname: Gamond
authors.affiliation: Department of Brain and Behavioral Sciences, University of Pavia.
authors.forename: Tomaso
authors.initials: T
authors.lastname: Vecchi
authors.affiliation: Department of Psychology, University of Milano-Bicocca.
authors.forename: Chiara
authors.initials: C
authors.lastname: Ferrari
authors.affiliation: The Laboratory for Visual Neuroplasticity, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School.
authors.forename: Lotfi B
authors.initials: LB
authors.lastname: Merabet
authors.affiliation: Department of Psychology, University of Milano-Bicocca.
authors.forename: Zaira
authors.initials: Z
authors.lastname: Cattaneo
mesh_terms: D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D001766:Blindness / Q000503:physiopathology*; D001921:Brain / Q000502:physiology*; D004644:Emotions / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012938:Social Perception; D055815:Young Adult