title: Conventional and alternative treatment approaches forClostridium difficileinfection.
abstract: Clostridium difficile-associated disease continues to be one of the leading health concerns worldwide.C. difficileis considered as a causative agent of nosocomial diarrhea that causes serious infection, which may result in death. The incidences ofC. difficileinfection (CDI) in developed countries have become increasingly high which may be attributed to the emergence of newer epidemic strains, extensive use of antibiotics, and limited alternative therapies. The available treatment options against CDI are expensive and promote resistance. Therefore, there is urgent need for new approaches to meet these challenges. This review discusses the current understanding of CDI, the existing clinical treatment strategies and future potential options as antidifficile agents based on the available published works.
authors.affiliation: Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah, KSA.
authors.forename: Khalid M
authors.initials: KM
authors.lastname: Aljarallah
keywords: Alternative treatment; Clostridium difficile; Clostridium difficile infection