title: Prevalence of metabolic syndrome and degree of cardiovascular disease risk in patients with Psoriatic Arthritis.
abstract: OBJECTIVE
  The aim of this study was to identify the prevalence of metabolic syndrome (MetS) and degree of cardiovascular disease (CVD) risk in patients with psoriatic arthritis (PsA).
  
  
  METHODS
  We performed a cross-sectional study on 102 adult patients with PsA and a control group of 102 patients with rheumatoid arthritis (RA). MetS was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) and International Diabetes Federation (IDF) criteria. The Framingham risk scores of 10-year risk of CVDs and coronary heart disease (CHD) were also calculated.
  
  
  RESULTS
  The prevalence of MetS was higher in patients with PsA than in those with RA, according to the NCEP-ATP III (40.6% vs. 24.7%, respectively; p=0.019) and IDF (46.8% vs. 27.9%, respectively; p=0.05) criteria. The prevalence of MetS was higher in female patients with PsA (p=0.009) than in male patients. A significantly increased prevalence of hypertriglyceridemia was determined in patients with PsA (p=0.019). No significant difference existed between the two groups with respect to 10-year CVD (p=0.333) and CHD (p=0.798) risks. Additionally, there were no significant differences between the clinical subtypes of PsA with regard to MetS (p=0.229).
  
  
  CONCLUSIONS
  MetS prevalence increased in patients with PsA compared with those with RA, whereas the risks were similar for CVDs and CHD. For this reason, optimal protection measures should be taken and guidelines should be applied to achieve adequate metabolic control in patients with PsA.
authors.affiliation: Department of Internal Medicine, Şişli Etfal Training and Research Hospital, İstanbul, Turkey.
authors.forename: Sıdıka Gülkan
authors.initials: SG
authors.lastname: Özkan
authors.affiliation: Department of Microbiology, Akdeniz University School of Medicine, Antalya, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Yazısız
authors.affiliation: Department of Internal Medicine, Şişli Etfal Training and Research Hospital, İstanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Behlül
authors.affiliation: Department of Internal Medicine, Şişli Etfal Training and Research Hospital, İstanbul, Turkey.
authors.forename: Yüksel Aslı
authors.initials: YA
authors.lastname: Gökbelen
authors.affiliation: Department of Internal Medicine, Şişli Etfal Training and Research Hospital, İstanbul, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Borlu
authors.affiliation: Department of Internal Medicine, Şişli Etfal Training and Research Hospital, İstanbul, Turkey; Division of Rheumatology, Department of Internal Medicine, Akdeniz University School of Medicine, Antalya, Turkey.
authors.forename: Veli
authors.initials: V
authors.lastname: Yazısız
keywords: Psoriatic arthritis; cardiovascular disease; coronary heart disease; metabolic syndrome; rheumatoid arthritis