title: Subfoveal Choroidal Vascularity in Myopia: Evidence From Spectral-Domain Optical Coherence Tomography.
abstract: To evaluate subfoveal choroidal vascularity in eyes with myopia in comparison to age-matched healthy subjects.
  
  
  
  Retrospective analysis of single foveal enhanced depth imaging optical coherence tomography (EDI-OCT) scans of 30 eyes with myopia (axial length greater than 25 mm). Subfoveal choroidal vascularity was evaluated by calculating vessel-area-to-stromal-area ratio using a previously validated automated algorithm.
  
  
  
  The subfoveal stromal area was significantly smaller in myopes (0.95 mm3± 0.22 mm3) compared to controls (1.33 mm3± 0.23 mm3; P < .0001). However, there was no significant difference in vascular area or in vessel-area-to-stroma-area ratio between the groups (P = .15 and P = .16, respectively). Subfoveal choroidal vascularity percentage was also not significantly different between the two groups (P = .07).
  
  
  
  Subfoveal choroidal thinning in myopia is primarily associated with a reduction in choroidal stroma, not vascular components. This needs further exploration and has potential clinical applications. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:202-207.].
authors.forename: Rayan A
authors.initials: RA
authors.lastname: Alshareef
authors.forename: Mohammed K
authors.initials: MK
authors.lastname: Khuthaila
authors.forename: Abhilash
authors.initials: A
authors.lastname: Goud
authors.forename: Kiran Kumar
authors.initials: KK
authors.lastname: Vupparaboina
authors.forename: Soumya
authors.initials: S
authors.lastname: Jana
authors.forename: Jay
authors.initials: J
authors.lastname: Chhablani
mesh_terms: D000328:Adult; D002829:Choroid / Q000098:blood supply*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D005584:Fovea Centralis / Q000473:pathology; D006801:Humans; D008297:Male; D009216:Myopia / Q000175:diagnosis*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence / Q000379:methods*