title: Tyrosine Kinase Inhibitors for Non-Small Cell Lung Cancer and Eye Metastasis: Disease Relapse or a New Entity?
abstract: Lung cancer is still diagnosed during the advanced stage of the disease and most patients do not have the opportunity for surgical treatment, despite the new diagnostic equipment that has been made available in recent years, such as the radial and linear endobronchial ultrasound (EBUS) and electromagnetic fiberoptic bronchoscopy. However, novel targeted therapies with second generation tyrosine kinase inhibitors and immunotherapy are available. In this commentary, we will focus on eye metastasis after initiation of tyrosine kinase inhibitors due to epidermal growth factor mutation of lung cancer adenocarcinoma.
authors.affiliation: Pulmonary Department, Oncology Unit, G. Papanikolaou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Paul
authors.initials: P
authors.lastname: Zarogoulidis
authors.affiliation: Pulmonary Department, Oncology Unit, G. Papanikolaou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Sofia
authors.initials: S
authors.lastname: Lampaki
authors.affiliation: Pulmonary Department, Oncology Unit, G. Papanikolaou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Panos
authors.initials: P
authors.lastname: Chinelis
authors.affiliation: Oncology Department, G. Papageorgiou University General Hospital, Thessaloniki, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Lazaridis
authors.affiliation: Oncology Department, Interbalkan European Medical Center, Thessaloniki, Greece.
authors.forename: Sofia
authors.initials: S
authors.lastname: Baka
authors.affiliation: Pulmonary Department, Sotiria Hospital of Chest Diseases, Athens, Greece.
authors.forename: Aggeliki
authors.initials: A
authors.lastname: Rapti
keywords: Eye Metastasis; Non-Small Cell Lung Cancer; Tyrosine Kinase Inhibitor