title: Cognitive complaints in women with fibromyalgia: Are they due to depression or to objective cognitive dysfunction?
abstract: BACKGROUND
  Cognitive complaints are common in fibromyalgia, but it is unclear whether they represent an objective cognitive dysfunction or whether they could be explained by depressive symptoms. Here, we aim to elucidate the frequency of subjective cognitive complaints in a sample of women with fibromyalgia, in addition to analyzing associations between these subjective complaints and objective measures linked to the attention and executive cognitive domains. Finally, we aim to investigate the ability of demographic, clinical, and psychological variables to explain the subjective complaints observed.
  
  
  METHODS
  One hundred and five women aged 30-55 years diagnosed with fibromyalgia completed a neuropsychological assessment, which included measures of attention and executive functions. They also completed self-report inventories of subjective cognitive complaints, depression, anxiety, intensity of pain, sleep quality, everyday physical functioning, and quality of life.
  
  
  RESULTS
  Eighty-four percent of the patients reported subjective cognitive complaints. Depression scores, everyday physical functioning, and working memory performance were most strongly associated with subjective cognitive complaints. These three variables were significant predictors for subjective cognitive complaints with a final model explaining 32% of the variance.
  
  
  CONCLUSIONS
  Cognitive complaints are very frequent in patients with fibromyalgia, and these are related to functional and cognitive impairment as well as to depressive symptoms.
authors.affiliation: a Department of Medicine , Universitat de Lleida , Lleida , Spain.|b Consorci Sanitari de Terrassa , Clinical Research Group for Brain, Cognition and Behavior , Terrassa , Spain.
authors.forename: Olga
authors.identifier: http://orcid.org/0000-0002-0788-2486
authors.initials: O
authors.lastname: Gelonch
authors.affiliation: b Consorci Sanitari de Terrassa , Clinical Research Group for Brain, Cognition and Behavior , Terrassa , Spain.|c Neuropsychology Unit , Hospital de Terrassa, Consorci Sanitari de Terrassa , Terrassa , Spain.
authors.forename: Maite
authors.identifier: http://orcid.org/0000-0001-7443-8249
authors.initials: M
authors.lastname: Garolera
authors.affiliation: d Institute for Biomedical Research in Lleida Dr. Pifarré Foundation , IRBLLEDA, Universitat de Lleida, Hospital Universitari Arnau de Vilanova de Lleida , Lleida , Spain.
authors.forename: Joan
authors.initials: J
authors.lastname: Valls
authors.affiliation: e Reumatology Section, Fibromyalgia and Chronic Fatigue Syndrome Unit , GSS-Hospital Universitari de Santa Maria , Lleida , Spain.
authors.forename: Lluís
authors.initials: L
authors.lastname: Rosselló
authors.affiliation: d Institute for Biomedical Research in Lleida Dr. Pifarré Foundation , IRBLLEDA, Universitat de Lleida, Hospital Universitari Arnau de Vilanova de Lleida , Lleida , Spain.|f Department of Psychiatry , GSS-Hospital Universitari de Santa Maria , Lleida , Spain.|g Department of Mental Health , Sant Joan De Déu Terres de Lleida , Lleida , Spain.
authors.forename: Josep
authors.identifier: http://orcid.org/0000-0001-6284-4709
authors.initials: J
authors.lastname: Pifarré
mesh_terms: D000328:Adult; D060825:Cognitive Dysfunction / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D015897:Comorbidity; D003863:Depression / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*; D003866:Depressive Disorder / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D005356:Fibromyalgia / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*; D006801:Humans; D008570:Memory, Short-Term / Q000502:physiology*; D008875:Middle Aged
keywords: Cognitive complaints; depression; fibromyalgia; neuropsychology; working memory