title: [Silica-associated systemic sclerosis occurring after an occupational exposure to arc welding].
abstract: Crystalline silica-associated systemic sclerosis can occur in people operating arc welding. Diffuse scleroderma was diagnosed in a 57-year old plumber-welder suffering from inflammatory polyarthralgias, Raynaud's phenomenon, sclerodactyly, diffuse cutaneous scleroderma, telangiectasias, esophageal damage, pulmonary arterial hypertension and pulmonary fibrosis associated with the presence of anti-nucleosome antibodies. During his professional activity the patient was frequently exposed to high atmospheric concentrations of crystalline silica generated by arc-welding. The diagnosis of Erasmus syndrome associated with systemic sclerosis and pulmonary silicosis was retained. A report of work-related illness (table 17 in Tunisia) was made.
authors.affiliation: Service de Rhumatologie, CHU Farhat-Hached, Sousse, Tunisie.
authors.forename: Zeineb
authors.initials: Z
authors.lastname: Alaya
authors.affiliation: Service de Médecine du Travail, CHU Farhat-Hached, Sousse, Tunisie.
authors.forename: Houda
authors.initials: H
authors.lastname: Kalboussi
authors.affiliation: Service d'Orthopédie, CHU Sahloul, Sousse, Tunisie.
authors.forename: Walid
authors.initials: W
authors.lastname: Osman
authors.affiliation: Service d'Orthopédie, CHU Sahloul, Sousse, Tunisie.
authors.forename: Nader
authors.initials: N
authors.lastname: Naouar
authors.affiliation: Service de Rhumatologie, CHU Farhat-Hached, Sousse, Tunisie.
authors.forename: Héla
authors.initials: H
authors.lastname: Zeglaoui
authors.affiliation: Service de Rhumatologie, CHU Farhat-Hached, Sousse, Tunisie.
authors.forename: Elyès
authors.initials: E
authors.lastname: Bouajina
mesh_terms: D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000175:diagnosis / Q000503:physiopathology*; D016273:Occupational Exposure / Q000009:adverse effects*; D012595:Scleroderma, Systemic / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D012822:Silicon Dioxide / Q000633:toxicity; D012829:Silicosis / Q000175:diagnosis* / Q000503:physiopathology; D014416:Tunisia; D014896:Welding
chemical_list: D012822:Silicon Dioxide
keywords: Systemic sclerosis; occupational disease; silica crystalline