title: Failed epilepsy surgery: is this the end?
abstract: Resective epilepsy surgery can lead to sustained seizure control in 70-80% of patients evaluated for epilepsy surgery, indicating that up to 30% of patients still have recurrent seizures after surgery. Definitions of failed epilepsy surgery vary amongst studies. This review focuses on seizure outcome predictors after reoperation, possible mechanisms of failure and best management for this difficult patient population.
authors.affiliation: Department of Neurology, Center for Refractory Epilepsy, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Av. Hippocrate 10, 1200, Brussels, Belgium. riem.eltahry@uclouvain.be.|Department of Pneumology, Sleep Laboratory, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Av Hippocrate 10, 1200, Brussels, Belgium. riem.eltahry@uclouvain.be.
authors.forename: Riëm
authors.identifier: http://orcid.org/0000-0002-2440-0194
authors.initials: R
authors.lastname: El Tahry
authors.affiliation: Cleveland Clinic, Epilepsy Center, Cleveland, OH, 44195, USA.
authors.forename: Irene Zhong
authors.initials: IZ
authors.lastname: Wang
mesh_terms: D004569:Electroencephalography / Q000639:trends; D004827:Epilepsy / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000639:trends; D019635:Neurosurgical Procedures / Q000009:adverse effects / Q000639:trends*; D012086:Reoperation / Q000639:trends; D015899:Tomography, Emission-Computed, Single-Photon / Q000639:trends; D017211:Treatment Failure; D016896:Treatment Outcome
keywords: Epilepsy surgery; Failed surgery; Presurgical evaluation