title: Acral papular mucinosis: a new case of this rare entity.
abstract: Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to persist and may increase slowly in number. Histologically, hematoxylin-eosin and Alcian blue staining demonstrate mucin accumulation in the upper reticular dermis with separation of collagen fibers as a result of hyaluronic acid deposition. Treatment is rarely necessary due to the absence of symptoms. We present a 27-year-old healthy woman with asymptomatic papules on her upper extremities, which adequately meet clinical and pathological criteria of acral papular mucinosis.
authors.affiliation: Hospital General de Villarrobledo - Villarrobledo-Albacete, Spain.
authors.forename: María Encarnación
authors.initials: ME
authors.lastname: Gómez Sánchez
authors.affiliation: Complejo Universitario Hospitalario de Albacete - Castilla la Mancha, Spain.
authors.forename: Fernando de
authors.initials: F
authors.lastname: Manueles Marcos
authors.affiliation: Hospital General de Villarrobledo - Villarrobledo-Albacete, Spain.
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Martínez Martínez
authors.affiliation: Complejo Universitario Hospitalario de Albacete - Castilla la Mancha, Spain.
authors.forename: Roberto
authors.initials: R
authors.lastname: Vera Berón
authors.affiliation: Complejo Universitario Hospitalario de Albacete - Castilla la Mancha, Spain.
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: Azaña Défez
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D009077:Mucins / Q000032:analysis; D035583:Rare Diseases; D053718:Scleromyxedema / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*; D034941:Upper Extremity
chemical_list: D009077:Mucins