title: Green Synthesized Nanomaterials as Theranostic Platforms for Cancer Treatment: Principles, Challenges and the Road Ahead.
abstract: With the emergence of nanotechnology, new methods have been developed for engineering various nanoparticles for biomedical applications. Nanotheranostics is a burgeoning research field with tremendous prospects for the improvement of diagnosis and treatment of various cancers. However, the development of biocompatible and efficient drug/gene delivery theranostic systems still remains a challenge. Green synthetic approach of nanoparticles with low capital and operating expenses, reduced environmental pollution and better biocompatibility and stability is a latest and novel field, which is advantageous over chemical or physical nanoparticle synthesis methods. In this article, we summarize the recent research progresses related to green synthesized nanoparticles for cancer theranostic applications, and we also conclude with a look at the current challenges and insight into the future directions based on recent developments in these areas.
authors.affiliation: Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, Irvine, California 92618-1908, United States.
authors.forename: Pala
authors.initials: P
authors.lastname: Rajasekharreddy
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.|Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Huang
authors.affiliation: Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry- 605014, India.
authors.forename: Siddhardha
authors.initials: S
authors.lastname: Busi
authors.affiliation: Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry- 605014, India.
authors.forename: Jobina
authors.initials: J
authors.lastname: Rajkumari
authors.affiliation: Institute of Biomedical Science, National Sun Yat-sen University, Kaohsiung, Taiwan, China.
authors.forename: Ming-Hong
authors.initials: MH
authors.lastname: Tai
authors.affiliation: State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods; D005293:Ferritins / Q000737:chemistry / Q000627:therapeutic use; D006046:Gold / Q000737:chemistry / Q000627:therapeutic use; D055772:Green Chemistry Technology / Q000379:methods*; D006801:Humans; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use*; D036103:Nanotechnology / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D045663:Quantum Dots / Q000737:chemistry / Q000627:therapeutic use; D012643:Selenium / Q000737:chemistry / Q000627:therapeutic use; D000075462:Serum Albumin, Human / Q000737:chemistry / Q000627:therapeutic use; D012834:Silver / Q000737:chemistry / Q000627:therapeutic use; D000068936:Theranostic Nanomedicine / Q000379:methods*
chemical_list: D012834:Silver; D006046:Gold; D005293:Ferritins; D012643:Selenium; D000075462:Serum Albumin, Human
keywords: Green synthesis; bio-imaging; biocompatibility; cancer; nanoparticles; theranostics.