title: Reaching multidisciplinary consensus on classification of anaphylaxis for the eleventh revision of the World Health Organization's (WHO) International Classification of Diseases (ICD-11).
abstract: Although currently misclassified in the International Classification of Diseases (ICD) and still not officially listed as a rare disease, anaphylaxis is a well-known clinical emergency. Anaphylaxis is now one of the principal headings in the "Allergic and hypersensitivity conditions" section recently compiled for the forthcoming 11thRevision of ICD (ICD-11). We here report the building process used for the pioneering "Anaphylaxis" subsection of ICD-11 in which we aimed for transparency as recommended in the ICD-11 revision guidelines.
  
  
  
  During an online intensive scientific and technical discussions with ICD-11 Topic Advisory Groups and Expert Working Groups, we drafted a total of 35 proposals for the classification of anaphylaxis. From all the 35 proposals, 77% were implemented, 20% remain to be implemented, and the others being partially implemented (1.5%) or rejected (1.5%).
  
  
  
  For the first time, anaphylaxis is now properly classified and has attained greater visibility within ICD. In addition to all the benefits expected from the actions we have undertaken in updating the terminology, definitions and classification of allergic and hypersensitivity conditions for ICD-11, we strongly believe that anaphylaxis should be a public health priority and that it should therefore be formally added into the list of rare diseases in order to support awareness and quality clinical management of patients.
authors.affiliation: Hospital Sírio Libanês, São Paulo, Brazil. luciana.tanno@gmail.com.|Division of Allergy, Department of Pulmonology, Hôpital Arnaud de Villeneuve, University Hospital of Montpellier, 371, av. du Doyen Gaston Giraud, 34295, Montpellier cedex 5, France. luciana.tanno@gmail.com.|Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, 75013, Paris, France. luciana.tanno@gmail.com.
authors.forename: Luciana Kase
authors.initials: LK
authors.lastname: Tanno
authors.affiliation: Dermatology Topic Advisory Group, ICD-11 Revision Steering Group and Honorary Consultant Dermatologist, University of Manchester, Manchester, UK.
authors.forename: Robert J G
authors.initials: RJ
authors.lastname: Chalmers
authors.affiliation: Section of Allergy and Clinical Immunology, Imperial College London, National Heart and Lung Institute, Royal Brompton Hospital, London, UK.
authors.forename: Moises A
authors.initials: MA
authors.lastname: Calderon
authors.affiliation: INSERM, US14, Paris, France.
authors.forename: Ségolène
authors.initials: S
authors.lastname: Aymé
authors.affiliation: Division of Allergy, Department of Pulmonology, Hôpital Arnaud de Villeneuve, University Hospital of Montpellier, 371, av. du Doyen Gaston Giraud, 34295, Montpellier cedex 5, France.|Sorbonne Universités, UPMC Paris 06, UMR-S 1136, IPLESP, Equipe EPAR, 75013, Paris, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Demoly
mesh_terms: D000707:Anaphylaxis / Q000145:classification*; D006801:Humans; D038801:International Classification of Diseases; D014944:World Health Organization
keywords: Anaphylaxis; Classification; International Classification of Diseases; World Health Organization