title: Histiocytoid Sweet's syndrome presenting with annular erythematous plaques.
abstract: Histiocytoid Sweet's Syndrome is a rare inflammatory disease described in 2005 as a variant of the classical Sweet's Syndrome (SS). Histopathologically, the dermal inflammatory infiltrate is composed mainly of mononuclear cells that have a histiocytic appearance and represent immature myeloid cells. We describe a case of Histiocytoid Sweet's Syndrome in an 18-year-old man. Although this patient had clinical manifestations compatible with SS, the cutaneous lesions consisted of erythematous annular plaques, which are not typical for this entity and have not been described in histiocytic form so far. The histiocytic subtype was confirmed by histopathological analysis that showed positivity for myeloperoxidase in multiple cells with histiocytic appearance.
authors.affiliation: Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil.
authors.forename: Renata
authors.initials: R
authors.lastname: Marcarini
authors.affiliation: Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil.
authors.forename: Raquel Nardelli de
authors.initials: RN
authors.lastname: Araujo
authors.affiliation: Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil.
authors.forename: Monisa Martins
authors.initials: MM
authors.lastname: Nóbrega
authors.affiliation: Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
authors.forename: Karina Bittencourt
authors.initials: KB
authors.lastname: Medeiros
authors.affiliation: Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil.
authors.forename: Alexandre Carlos
authors.initials: AC
authors.lastname: Gripp
authors.affiliation: Universidade do Estado do Rio de Janeiro (UERJ) - Rio de Janeiro (RJ), Brazil.|Universidade Federal do Rio de Janeiro (UFRJ) - Rio de Janeiro (RJ), Brazil.
authors.forename: Juan Manuel Piñeiro
authors.initials: JM
authors.lastname: Maceira
mesh_terms: D000293:Adolescent; D001706:Biopsy; D004890:Erythema / Q000473:pathology*; D006644:Histiocytes / Q000473:pathology*; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000473:pathology; D012867:Skin / Q000473:pathology; D012873:Skin Diseases, Genetic / Q000473:pathology*; D016463:Sweet Syndrome / Q000473:pathology*