title: Bioactive Peptide of Marine Origin for the Prevention and Treatment of Non-Communicable Diseases.
abstract: Non-communicable diseases (NCD) are the leading cause of death and disability worldwide. The four main leading causes of NCD are cardiovascular diseases, cancers, respiratory diseases and diabetes. Recognizing the devastating impact of NCD, novel prevention and treatment strategies are extensively sought. Marine organisms are considered as an important source of bioactive peptides that can exert biological functions to prevent and treatment of NCD. Recent pharmacological investigations reported cardio protective, anticancer, antioxidative, anti-diabetic, and anti-obesity effects of marine-derived bioactive peptides. Moreover, there is available evidence supporting the utilization of marine organisms and its bioactive peptides to alleviate NCD. Marine-derived bioactive peptides are alternative sources for synthetic ingredients that can contribute to a consumer's well-being, as a part of nutraceuticals and functional foods. This contribution focus on the bioactive peptides derived from marine organisms and elaborates its possible prevention and therapeutic roles in NCD.
authors.affiliation: Research Center for Oceanography, Indonesian Institute of Sciences (LIPI), Jakarta 14430, Indonesia. ratih.pangestuti@lipi.go.id.
authors.forename: Ratih
authors.initials: R
authors.lastname: Pangestuti
authors.affiliation: Department of Marine-bio Convergence Science, Pukyong National University, Busan 608-737, Korea. sknkim@pknu.ac.kr.|Institute for Life Science of Seogo (ILSS), Kolmar Korea Co., Seoul 137-876, Korea. sknkim@pknu.ac.kr.
authors.forename: Se-Kwon
authors.initials: SK
authors.lastname: Kim
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000737:chemistry*; D001685:Biological Factors / Q000737:chemistry / Q000494:pharmacology*; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000517:prevention & control; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000517:prevention & control; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000517:prevention & control; D010455:Peptides / Q000737:chemistry / Q000494:pharmacology*; D012140:Respiratory Tract Diseases / Q000188:drug therapy / Q000517:prevention & control
chemical_list: D001685:Biological Factors; D010455:Peptides
keywords: bioactive peptide; marine; non-communicable diseases; prevention; treatment