title: Pathophysiology of dilatation of pupils due to scorpion and snake envenomation and its therapeutic value: Clinical observations.
abstract: Dilated nonreacting pupils are routinely taken as a sign of irreversible brain damage. Alpha-receptor stimulation (scorpion sting) and presynaptic acetylcholine receptor blocker (krait bite) may result in dilation of pupils without involvement of the brain. This study was aimed to clinically evaluate the response of pupils in scorpion sting and krait bite. Victims of scorpion sting and krait bite were chosen from Raigad district. Scorpion sting and krait bite cases were admitted to hospital and were clinically evaluated in detail regarding neurological manifestations. Both cases had nonreacting dilation of pupils, complete neurological recovery accompanied with reverse of pupillary size and its response to light. In scorpion sting and krait bite poisoning, dilated nonreacting pupils are not the signs of irreversible brain damage.
authors.affiliation: Bawaskar Hospital and Clinical Center, Mahad Raigad, Maharashtra, India.
authors.forename: Himmatrao S
authors.initials: HS
authors.lastname: Bawaskar
authors.affiliation: Department of Cardiology, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India.
authors.forename: Parag H
authors.initials: PH
authors.lastname: Bawaskar
authors.affiliation: Bawaskar Hospital and Clinical Center, Mahad Raigad, Maharashtra, India.
authors.forename: Pramodini H
authors.initials: PH
authors.lastname: Bawaskar
mesh_terms: D000818:Animals; D000997:Antivenins / Q000627:therapeutic use*; D017838:Bungarus; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015878:Mydriasis / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D011680:Pupil; D065008:Scorpion Stings / Q000175:diagnosis / Q000628:therapy*; D012605:Scorpions; D012909:Snake Bites / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000997:Antivenins