title: Gel or Die: Phase Separation as a Survival Strategy.
abstract: Stress conditions trigger protein assembly by demixing from the cytoplasm, but the biological significance is still unclear. In this issue of Cell, Riback et al. report that the yeast poly(A)-binding protein 1 (Pab1) is a phase-separating stress sensor that boosts organismal fitness under physiological stress conditions.
authors.affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
authors.forename: Sonja
authors.initials: S
authors.lastname: Kroschwald
authors.affiliation: Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany. Electronic address: alberti@mpi-cbg.de.
authors.forename: Simon
authors.initials: S
authors.lastname: Alberti
mesh_terms: D003593:Cytoplasm / Q000378:metabolism; D039122:Poly(A)-Binding Protein I / Q000378:metabolism*; D039102:Poly(A)-Binding Proteins / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000378:metabolism*
chemical_list: D039122:Poly(A)-Binding Protein I; D039102:Poly(A)-Binding Proteins; D011506:Proteins