title: FDG PET/CT in Pediatric Neurolymphomatosis.
abstract: An 8-year-old girl presented with back and leg pain and left arm and leg paresis. Lumbar puncture was suggestive of lymphocytic meningitis without identified organism. A second lumbar puncture demonstrated a large number of lymphoid B cells, with positive immunohistochemical staining for CD20 and CD25, proving the diagnosis of neurolymphomatosis. Brain and spine MRI demonstrated involvement of cervical and lumbosacral nerve roots. FDG PET/CT showed multiple bone metastases in addition to nerve involvement. Postchemotherapy FDG PET/CT demonstrated complete metabolic response.
authors.affiliation: From the *Service de Médecine Nucléaire, Pellegrin, CHU de Bordeaux, Bordeaux; †Service de Pédiatrie Médicale, Hématologie Pédiatrique, Pellegrin, CHU de Bordeaux, Bordeaux; ‡Service de Radiologie et d'Imagerie Anténatale, de l'Enfant et de la Femme, Pellegrin, CHU de Bordeaux; §INCIA, UMR CNRS 5287, Bordeaux; and ∥Université de Bordeaux, Bordeaux, France.
authors.forename: Carole
authors.initials: C
authors.lastname: de Vaugelade
authors.forename: Henri
authors.initials: H
authors.lastname: de Clermont-Gallerande
authors.forename: Marie
authors.initials: M
authors.lastname: Meyer
authors.forename: Aude
authors.initials: A
authors.lastname: My Duyen Tiphaine
authors.forename: Alice
authors.initials: A
authors.lastname: Benjamin
authors.forename: Stephane
authors.initials: S
authors.lastname: Ducassou
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Chateil
authors.forename: Philippe
authors.initials: P
authors.lastname: Fernandez
mesh_terms: D000818:Animals; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D002648:Child; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008380:Marek Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18