title: Mycosis fungoides and Kaposi's sarcoma association in an HIV-negative patient.
abstract: The association of mycosis fungoides and kaposi's sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) - associated with all forms of Kaposi's sarcoma - has also been recently identified in mycosis fungoides lesions. However, a causal association between HHV-8 and the onset of mycosis fungoides has not been established yet. The present case reports a patient who developed Kaposi's sarcoma lesions after a two-year UVB phototherapy to treat a mycosis fungoides. Negative immunohistochemistry staining for Kaposi's sarcoma-associated herpesvirus in the initial mycosis fungoides lesions strengthens the absence of a link between Kaposi's sarcoma-associated herpesvirus and mycosis fungoides. Immunosuppression caused by the lymphoma and prolonged phototherapy were probably the contribut ing factors for the onset of Kaposi's sarcoma.
authors.affiliation: Universidade Federal de Goiás (UFG) - Goiânia (GO), Brazil.
authors.forename: Maria Carolina Prado Fleury
authors.initials: MC
authors.lastname: Bariani
authors.affiliation: Universidade Federal de Goiás (UFG) - Goiânia (GO), Brazil.
authors.forename: Luiz Fernando Fróes
authors.initials: LF
authors.lastname: Fleury
authors.affiliation: Universidade Federal de Goiás (UFG) - Goiânia (GO), Brazil.
authors.forename: Ana Maria Quinteiro
authors.initials: AM
authors.lastname: Ribeiro
authors.affiliation: Universidade Federal de Goiás (UFG) - Goiânia (GO), Brazil.
authors.forename: Siderley de Souza
authors.initials: SS
authors.lastname: Carneiro
authors.affiliation: Universidade Federal de Goiás (UFG) - Goiânia (GO), Brazil.
authors.forename: Tiago Arantes
authors.initials: TA
authors.lastname: Pereira
mesh_terms: D001706:Biopsy; D019288:Herpesvirus 8, Human / Q000302:isolation & purification; D006801:Humans; D007150:Immunohistochemistry; D007165:Immunosuppression Therapy; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D010789:Phototherapy; D012514:Sarcoma, Kaposi / Q000276:immunology / Q000473:pathology* / Q000821:virology*; D012867:Skin / Q000473:pathology / Q000821:virology; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology* / Q000821:virology*