title: Sterolomics: State of the art, developments, limitations and challenges.
abstract: Sterolomics can be thought of as the quantitative determination of the entire complement of molecules based on the cyclopentanoperhydrophenanthrene skeleton in a system. Mass spectrometry is the dominant analytical technology employed. In this article we highlight some pitfalls in analysis, data interpretation and annotation. We give our opinion on how some of these pitfalls can best be avoided. This article is part of a Special Issue entitled: BBALIP_Lipidomics Opinion Articles edited by Sepp Kohlwein.
authors.affiliation: Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK. Electronic address: w.j.griffiths@swansea.ac.uk.
authors.forename: William J
authors.initials: WJ
authors.lastname: Griffiths
authors.affiliation: Swansea University Medical School, Singleton Park, Swansea SA2 8PP, UK. Electronic address: y.wang@swansea.ac.uk.
authors.forename: Yuqin
authors.initials: Y
authors.lastname: Wang
mesh_terms: D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D010616:Phenanthrenes / Q000737:chemistry; D013261:Sterols / Q000737:chemistry*
chemical_list: D010616:Phenanthrenes; D013261:Sterols; C031181:phenanthrene
keywords: 7-Dehydrocholesterol; Cholesterol; Free radical reaction; Mass spectrometry; Oxysterol; Sterol