title: The activation of a neuralizing factor in the neural plate is correlated with its homoiogenetic-inducing activity.
abstract: Neural plates which are induced in the dorsal ectoderm of Triturus by the underlying mesoderm acquire, in turn, neural-inducing activity. This process is correlated with the appearance of neural-inducing activity in the microsomal fraction of the neural plate homogenate. The high-speed supernatant also acquires inducing activity after neural induction, but to a lesser extent. The experiments suggest that a masked neuralizing factor, which is already present in the ectoderm, is in part activated and exported from the inducing neural plate cells.
authors.affiliation: Abteilung für Biologie (Zoophysiologie), Universität Essen, Universitätsstraße 5, D-4300, Essen 1, Germany.
authors.forename: Horst
authors.initials: H
authors.lastname: Grunz
authors.affiliation: Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, D-1000, Berlin 33.
authors.forename: Jochen
authors.initials: J
authors.lastname: Born
authors.affiliation: Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, D-1000, Berlin 33.
authors.forename: Heinz
authors.initials: H
authors.lastname: Tiedemann
authors.affiliation: Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, D-1000, Berlin 33.
authors.forename: Hildegard
authors.initials: H
authors.lastname: Tiedemann
keywords: Activation of masked factor; Neural induction; Neural plate