title: Immunohistochemical Staining of Pediatric Solitary Angiokeratomas.
abstract: The precise etiology and subtype of vessels constituting angiokeratomas is poorly understood. We sought to characterize the vessels by studying prospero-related homeobox gene-1 and D2-40 expression in 22 pediatric solitary angiokeratomas. Routine histologic examination demonstrated a mix of lymph-containing vessels and erythrocyte-filled small vessels. Our results suggest that angiokeratomas may in part be comprised of vessels with lymphatic differentiation.
authors.affiliation: Division of Dermatology, Children's Mercy-Kansas City, Kansas City, Missouri.
authors.forename: Brea
authors.initials: B
authors.lastname: Prindaville
authors.affiliation: Department of Dermatology, College of Medicine, University of Oklahoma, Oklahoma City, Oklahoma.
authors.forename: Hillary
authors.initials: H
authors.lastname: Lawrence
authors.affiliation: Department of Pathology, Children's Mercy-Kansas City, Kansas City, Missouri.
authors.forename: Vivekanand
authors.initials: V
authors.lastname: Singh
authors.affiliation: Division of Dermatology, Children's Mercy-Kansas City, Kansas City, Missouri.
authors.forename: Amy J
authors.initials: AJ
authors.lastname: Nopper
authors.affiliation: Division of Dermatology, Children's Mercy-Kansas City, Kansas City, Missouri.
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Horii
mesh_terms: D000293:Adolescent; D000794:Angiokeratoma / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology*