title: First report of a simultaneous transcatheter mitral valve-in-valve and aortic valve replacement in a left ventricular assist device patient.
abstract: Transcatheter aortic valve replacement is standard of care for patients with severe aortic stenosis at high risk for surgical aortic valve replacement. Although not intended for treatment of primary aortic insufficiency, several transcatheter aortic valve prostheses have been used to treat patients with severe aortic insufficiency (AI), including patients with left ventricular assist devices (LVAD), in whom significant AI is not uncommon. Similarly, transcatheter valve replacements have been used for valve-in-valve treatment, in the pulmonary, aortic, and mitral positions, either via a retrograde femoral approach or antegrade transseptal approach (mitral valve-in-valve). In this case report, we report an LVAD patient with severe aortic insufficiency and severe bioprosthetic mitral prosthetic stenosis, in whom we successfully performed transfemoral aortic valve replacement and transfemoral mitral valve-in-valve replacement via a transseptal approach. © 2017 Wiley Periodicals, Inc.
authors.affiliation: Piedmont Heart Institute and Marcus Heart Valve Center, Atlanta, Georgia.
authors.forename: Christopher
authors.initials: C
authors.lastname: Meduri
authors.affiliation: Piedmont Heart Institute and Marcus Heart Valve Center, Atlanta, Georgia.
authors.forename: James
authors.initials: J
authors.lastname: Kauten
authors.affiliation: Piedmont Heart Institute and Marcus Heart Valve Center, Atlanta, Georgia.
authors.forename: Mani
authors.initials: M
authors.lastname: Vannan
authors.affiliation: Piedmont Heart Institute and Marcus Heart Valve Center, Atlanta, Georgia.
authors.forename: Vivek
authors.identifier: http://orcid.org/0000-0002-1718-3435
authors.initials: V
authors.lastname: Rajagopal
mesh_terms: D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006328:Cardiac Catheterization / Q000295:instrumentation* / Q000379:methods; D018618:Echocardiography, Doppler, Color; D019560:Echocardiography, Three-Dimensional; D017548:Echocardiography, Transesophageal; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D006353:Heart-Assist Devices; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008946:Mitral Valve Stenosis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D011474:Prosthesis Design; D011475:Prosthesis Failure; D020127:Recovery of Function; D012720:Severity of Illness Index; D065467:Transcatheter Aortic Valve Replacement / Q000295:instrumentation*; D016896:Treatment Outcome; D016277:Ventricular Function, Left
keywords: aortic valve disease; mitral valve disease; percutaneous intervention; percutaneous valve therapy; structural heart disease intervention; transcatheter valve implantation; ventricular assist device