title: The study of biochemical profile of cyst fluid and diffusion-weighted magnetic resonance imaging in differentiating hepatic hydatid cysts from liver simple cysts.
abstract: OBJECTIVE
  The aim of this study was to investigate the value of biochemical profile of cyst fluid and diffusion-weighted imaging (DWI) in differentiating hepatic hydatid cysts (HCs) from liver simple cysts.
  
  
  METHODS
  Forty-six patients underwent MR imaging. Twenty-nine patients had 29 hydatid cysts and 17 patients had liver simple cysts. Thirteen patients with hydatid cysts and seven patients with liver simple cysts were evaluated with cyst fluid biochemical analysis. The concentration of glucose, protein, calcium ion (Ca2+) electrolyte, macroscopic appearance, and parasitological sediment were evaluated in this study.
  
  
  RESULTS
  In the respect of biochemical analysis cyst fluid, the concentration of glucose and calcium ion of HCs was significantly higher than that of the liver simple cysts. In the respect of DWI, in the b 1000 s/mm2value in respect of mean application data center (ADC) values, there was a statistically significant difference between HCs group (the mean value was (2.50±0.79)×10-3mm/s2) and liver simple cysts group (the mean value was (2.92±0.66)×10-3mm/s2). However, no statistically significant results were obtained in the ADC measurements of b 500 s/mm2between two groups.
  
  
  CONCLUSIONS
  The analysis of cyst fluid combined with the measurement of ADC values in the b 1000 s/mm2value could be considered a promising parameter as an alternative to the differential diagnosis of hepatic hydatid cysts from liver simple cysts.
authors.affiliation: Department of Radiology, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.|Department of Radiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
authors.forename: Wang
authors.identifier: http://orcid.org/0000-0002-2150-8108
authors.initials: W
authors.lastname: Shanshan
authors.affiliation: Department of Radiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
authors.forename: Li
authors.initials: L
authors.lastname: Hui
authors.affiliation: Department of Radiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
authors.forename: Liu
authors.initials: L
authors.lastname: Yan
authors.affiliation: Department of Orthopaedics, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Radiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
authors.forename: Ren
authors.initials: R
authors.lastname: Yongfang
authors.affiliation: Department of Radiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Yan
authors.affiliation: Department of Radiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
authors.forename: Muhetarjiang
authors.initials: M
authors.lastname: Kader
authors.affiliation: Department of Radiology, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Wenxiao
mesh_terms: D000328:Adult; D002118:Calcium / Q000032:analysis; D020420:Cyst Fluid / Q000737:chemistry* / Q000000981:diagnostic imaging*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004444:Echinococcosis, Hepatic / Q000000981:diagnostic imaging* / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000032:analysis; D006801:Humans; D008099:Liver / Q000737:chemistry / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D055815:Young Adult
chemical_list: D005947:Glucose; D002118:Calcium
keywords: cyst fluid; diffusion-weighted imaging; hydatid cysts; liver simple cysts