title: Siderotic cataract with no signs of intraocular foreign body.
abstract: BACKGROUND
  Ocular siderosis is a clinical condition induced by deposition of an iron-containing intraocular foreign body. We report a unique case of histopathologically proven lens siderosis in a young woman with a preceding history of trauma but no signs of retained intraocular foreign body.
  
  
  METHODS
  A 32-year-old woman presented with an opacified lens showing brownish deposits on the anterior capsule and underwent cataract surgery. Preoperative ophthalmic examination did not show any retained intraocular foreign body. Histopathologic staining of the anterior capsule confirmed the presence of iron deposits and macrophages. Electroretinography examination performed in the postoperative period showed the changes characteristic of retinal degeneration in ocular siderosis.
  
  
  CONCLUSIONS
  This case illustrates the importance of close monitoring of patients with a history of trauma or previous penetrating injury to the eye, even if there is no intraocular foreign body, because they might develop ocular siderosis at a later stage. This case report underscores the importance of electroretinography and histopathologic analysis, in addition to ophthalmic examination, in the diagnosis of ocular siderosis.
authors.affiliation: Eye Institute, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China.|Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China.|Key Laboratory of Myopia, Ministry of Health PR China, Shanghai, 200031, China.|Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, 200031, China.
authors.forename: Ke-Ke
authors.initials: KK
authors.lastname: Zhang
authors.affiliation: Eye Institute, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China.|Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China.|Key Laboratory of Myopia, Ministry of Health PR China, Shanghai, 200031, China.|Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, 200031, China.
authors.forename: Wen-Wen
authors.initials: WW
authors.lastname: He
authors.affiliation: Eye Institute, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China. luyieent@126.com.|Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China. luyieent@126.com.|Key Laboratory of Myopia, Ministry of Health PR China, Shanghai, 200031, China. luyieent@126.com.|Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, 200031, China. luyieent@126.com.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Eye Institute, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China. zhuxiangjia1982@163.com.|Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, 200031, China. zhuxiangjia1982@163.com.|Key Laboratory of Myopia, Ministry of Health PR China, Shanghai, 200031, China. zhuxiangjia1982@163.com.|Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, 200031, China. zhuxiangjia1982@163.com.
authors.forename: Xiang-Jia
authors.initials: XJ
authors.lastname: Zhu
mesh_terms: D000328:Adult; D002386:Cataract / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism; D004596:Electroretinography; D005129:Eye Foreign Bodies / Q000175:diagnosis; D005260:Female; D006485:Hemosiderin / Q000378:metabolism*; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000378:metabolism / Q000473:pathology*; D012806:Siderosis / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014792:Visual Acuity
chemical_list: D006485:Hemosiderin
keywords: Case report; Cataract; Electroretinography; Histopathology; Intraocular foreign body; Ocular siderosis