title: Body composition changes in the first month after sleeve gastrectomy based on gender and anatomic site.
abstract: BACKGROUND
  Sleeve gastrectomy (SG) induces acute weight loss, but its impact on the very early postoperative changes in body composition (BC) is less clear.
  
  
  OBJECTIVE
  This longitudinal study examined the BC changes in the first month after SG according to gender and anatomic site.
  
  
  METHODS
  BC (lean tissue mass [LTM] and fat mass [FM]) were determined by dual-energy x-ray absorptiometry in 41 obese patients (33 women, 80.5%) just before SG and 1 month later.
  
  
  METHODS
  University hospital of Montpellier, France.
  
  
  RESULTS
  One month after SG, mean weight loss was -9.8±2.6 kg, with a significant decrease in LTM and FM (kg) ranging from -7.3% to 9.5%, depending on site. FM (kg) loss in men exceeded that in women at whole body, upper limbs, and trunk. FM (%) and the LTM/FM ratio decreased only in the trunk in men and the lower limbs in women, but the gender difference was only observed for the trunk. In women, age was positively correlated with relative FM variation (% and kg) in the lower limbs and negatively correlated with LTM and LTM/FM. In men, weight was negatively correlated with the relative LTM and FM (kg) variations in the upper limbs.
  
  
  CONCLUSIONS
  SG induces acute weight loss, but this loss comprises losses in both FM and LTM. Because excessive LTM loss can have deleterious consequences, preventive strategies should be implemented soon after bariatric surgery. The specific changes in BC are highlighted according to gender and anatomic site.
authors.affiliation: Service de Médecine Nucléaire, Hôpital Lapeyronie, Centre Hospitalier Régional Universitaire (CHRU) Montpellier et Université Montpellier (UM), Montpellier, France; Physiologie et Médecine Expérimentale du Cœur et des Muscles (PhyMedExp), U1046 INSERM, UMR9214 CNRS, University of Montpellier, Montpellier, France. Electronic address: l-maimoun@chu-montpellier.fr.
authors.forename: Laurent
authors.initials: L
authors.lastname: Maïmoun
authors.affiliation: Departement d'Endocrinology, Diabetes, Nutrition, Hôpital Lapeyronie, CHRU, Montpellier, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Lefebvre
authors.affiliation: Unité de recherche clinique, biostatistiques et épidémiologie, Département de l'Information Médicale, CHRU, Montpellier, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Jaussent
authors.affiliation: Service de Chirurgie Digestive A, Hôpital Saint Eloi, CHRU, Montpellier, France.
authors.forename: Clémence
authors.initials: C
authors.lastname: Fouillade
authors.affiliation: Service de Médecine Nucléaire, Hôpital Lapeyronie, Centre Hospitalier Régional Universitaire (CHRU) Montpellier et Université Montpellier (UM), Montpellier, France; Physiologie et Médecine Expérimentale du Cœur et des Muscles (PhyMedExp), U1046 INSERM, UMR9214 CNRS, University of Montpellier, Montpellier, France.
authors.forename: Denis
authors.initials: D
authors.lastname: Mariano-Goulart
authors.affiliation: Service de Chirurgie Digestive A, Hôpital Saint Eloi, CHRU, Montpellier, France.
authors.forename: David
authors.initials: D
authors.lastname: Nocca
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology; D000293:Adolescent; D000328:Adult; D000368:Aged; D050110:Bariatric Surgery / Q000379:methods*; D001823:Body Composition / Q000502:physiology*; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D011182:Postoperative Care; D011446:Prospective Studies; D012727:Sex Characteristics; D015431:Weight Loss / Q000502:physiology; D055815:Young Adult
keywords: Bariatric surgery; Body composition; Fat mass; Lean tissue mass; Sleeve gastrectomy