title: Copper- and Palladium-Catalyzed Cross-Coupling Reactions for the Synthesis of N-Fused Benzo[4,5]imidazo[2,1-b]thiazole Derivatives via Substituted trans-1,2-Diiodoalkenes, 1H-Benzo[d]imidazole-2-thiols, and Halobenzenes.
abstract: Two transition metal (Cu and Pd)-catalyzed C-S, C-N, and C-C bond cross-coupling reactions for the preparation of N-fused benzo[4,5]imidazo[2,1-b]thiazole derivatives were developed. A variety of 3-substituted and 2,3-disubstituted benzo[4,5]imidazo[2,1-b]thiazoles were efficiently and conveniently synthesized from the coupling reaction via trans-1,2-diiodoalkenes, 1H-benzo[d]imidazole-2-thiols, and halobenzenes in moderate to excellent yields.
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Guodong
authors.identifier: 0000-0002-0631-1913
authors.initials: G
authors.lastname: Shen
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Bingchuan
authors.initials: B
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Xianqiang
authors.initials: X
authors.lastname: Huang
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Yaxin
authors.initials: Y
authors.lastname: Hou
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Huan
authors.initials: H
authors.lastname: Gao
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Jichun
authors.initials: J
authors.lastname: Cui
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Chuansheng
authors.initials: C
authors.lastname: Cui
authors.affiliation: School of Chemistry and Chemical Engineering, School of Pharmacy, Liaocheng University , Liaocheng, 252000 Shandong, P. R. China.
authors.forename: Tongxin
authors.initials: T
authors.lastname: Zhang