title: Atypical Neuroleptic Malignant Syndrome Associated with Use of Clozapine.
abstract: The Neuroleptic Malignant Syndrome (NMS) is a medical emergency of infrequent presentation in the emergency department, which is associated with the use of psychiatric drugs, such as typical and atypical antipsychotics. Our case addresses a 55-year-old patient diagnosed with undifferentiated schizophrenia for 10 years, who had been receiving clozapine and clonazepam as part of their treatment. This patient presents the symptoms of Neuroleptic Malignant Syndrome without fever, which improves with treatment especially with the withdrawal of clozapine. In the absence of fever and clinical improvement, the patient is considered to have an atypical presentation of this disease.
authors.affiliation: Emergency Department, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Quevedo-Florez
authors.identifier: 0000-0002-7655-7548
authors.initials: QF
authors.lastname: Leonardo
authors.affiliation: Emergency Department, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Granada-Romero
authors.initials: GR
authors.lastname: Juliana
authors.affiliation: Emergency Department, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Camargo-Arenas Juan
authors.initials: CJ
authors.lastname: Fernando