title: Deaths Associated with Ankylosing Spondylitis in France from 1969 to 2009.
abstract: To describe deaths for which ankylosing spondylitis (AS) was on death certificates in France.
  
  
  
  Death certificates in which AS was indicated were evaluated. Standard mortality ratio (SMR) was assessed.
  
  
  
  AS appeared in 2940 death certificates. The mortality rate of AS seemed stable. The most frequent initial causes were diseases of the circulatory system [28.3% in the International Classification of Diseases, 10th ed (ICD-10)]. SMR adjusted for age and sex were 2.1 (95% CI 1.45-2.91) for infections and 0.43 (0.36-0.5) for cancers (ICD-10 period).
  
  
  
  This study found an increase in mortality from infectious and external causes of death; conversely, patients with AS appear to die less frequently from cancer.
authors.affiliation: From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France. praticlement@gmail.com.|C. Prati, MD, PhD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; M. Puyraveau, PhD, Centre de Méthodologie Clinique, CHU Besançon; X. Guillot, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; F. Verhoeven, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; D. Wendling, MD, PhD, Professor, Department of Rheumatology, CHU Besançon, and EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté. praticlement@gmail.com.
authors.forename: Clément
authors.initials: C
authors.lastname: Prati
authors.affiliation: From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France.|C. Prati, MD, PhD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; M. Puyraveau, PhD, Centre de Méthodologie Clinique, CHU Besançon; X. Guillot, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; F. Verhoeven, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; D. Wendling, MD, PhD, Professor, Department of Rheumatology, CHU Besançon, and EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté.
authors.forename: Marc
authors.initials: M
authors.lastname: Puyraveau
authors.affiliation: From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France.|C. Prati, MD, PhD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; M. Puyraveau, PhD, Centre de Méthodologie Clinique, CHU Besançon; X. Guillot, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; F. Verhoeven, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; D. Wendling, MD, PhD, Professor, Department of Rheumatology, CHU Besançon, and EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté.
authors.forename: Xavier
authors.initials: X
authors.lastname: Guillot
authors.affiliation: From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France.|C. Prati, MD, PhD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; M. Puyraveau, PhD, Centre de Méthodologie Clinique, CHU Besançon; X. Guillot, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; F. Verhoeven, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; D. Wendling, MD, PhD, Professor, Department of Rheumatology, CHU Besançon, and EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté.
authors.forename: Franck
authors.initials: F
authors.lastname: Verhoeven
authors.affiliation: From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France.|C. Prati, MD, PhD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; M. Puyraveau, PhD, Centre de Méthodologie Clinique, CHU Besançon; X. Guillot, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; F. Verhoeven, MD, Department of Rheumatology, CHU Besançon, and FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; D. Wendling, MD, PhD, Professor, Department of Rheumatology, CHU Besançon, and EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté.
authors.forename: Daniel
authors.initials: D
authors.lastname: Wendling
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D003644:Death Certificates; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000401:mortality*
keywords: ANKYLOSING SPONDYLITIS; DEATH CERTIFICATE; MORTALITY