title: [Pleiotropic Effects of Rosuvastatin in Patients With High Cardiovascular Risk].
abstract: hronic obstructive pulmonary disease (COPD) is the third leading cause of death in the list of common causes of mortality after cardiovascular diseases. The processes of atherogenesis and cardiovascular diseases are accelerated in patients with COPD. The key mechanisms of COPD pathogenesis are oxidative stress, depletion of antioxidant protection, development of the pulmonary and systemic inflammation and the development of endothelial dysfunction. This article discusses the pleiotropic effects of statins in patients with COPD.
authors.affiliation: Moscow State University of Medicine and Dentistry named after A.I. Evdokimov Moscow, Russia; Children hospital of St. Vladimir, Moscow, Russia.
authors.forename: E I
authors.initials: EI
authors.lastname: Samorukova
authors.affiliation: Moscow State University of Medicine and Dentistry named after A.I. Evdokimov Moscow, Russia; Children hospital of St. Vladimir, Moscow, Russia.
authors.forename: T V
authors.initials: TV
authors.lastname: Adasheva
authors.affiliation: Moscow State University of Medicine and Dentistry named after A.I. Evdokimov Moscow, Russia; Children hospital of St. Vladimir, Moscow, Russia.
authors.forename: V S
authors.initials: VS
authors.lastname: Zadionchenko
authors.affiliation: Moscow State University of Medicine and Dentistry named after A.I. Evdokimov Moscow, Russia; Children hospital of St. Vladimir, Moscow, Russia.
authors.forename: G A
authors.initials: GA
authors.lastname: Rosliakova