title: Efficacy of Intravenous and Endotracheal Epinephrine during Neonatal Cardiopulmonary Resuscitation in the Delivery Room.
abstract: A retrospective examination is presented of intravenous vs a lower (0.03?mg/kg) and higher (0.05?mg/kg) dose of endotracheal epinephrine during delivery room cardiopulmonary resuscitation. Repeated dosing of intravenous and endotracheal epinephrine is needed frequently for successful resuscitation. Research regarding optimal dosing for both routes is needed critically.
authors.affiliation: Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: cecilie.halling@childrens.com.
authors.forename: Cecilie
authors.initials: C
authors.lastname: Halling
authors.affiliation: Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: John E
authors.initials: JE
authors.lastname: Sparks
authors.affiliation: Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: Lucy
authors.initials: L
authors.lastname: Christie
authors.affiliation: Division of Neonatal-Perinatal Medicine, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: Myra H
authors.initials: MH
authors.lastname: Wyckoff
mesh_terms: D001238:Asphyxia Neonatorum / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D003696:Delivery Rooms; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000008:administration & dosage*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000453:epidemiology; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D007442:Intubation, Intratracheal; D008297:Male; D012189:Retrospective Studies; D013781:Texas / Q000453:epidemiology
chemical_list: D001993:Bronchodilator Agents; D004837:Epinephrine
keywords: endotracheal tube epinephrine; intravenous epinephrine; neonatal resuscitation; return of spontaneous circulation