title: Three Cases of Escherichia coli Meningitis in Chicks Imported to Japan.
abstract: Three outbreaks of colibacillosis have occurred in chicks during the quarantine period after importation to Japan. All three were derived from three different countries without epidemiologic relevance. Some birds from each infected flock were examined pathologically and bacteriologically. The characteristic histologic finding common to all three cases was severe bacterial meningitis in the central nervous system. Pericarditis, perihepatitis, and omphalitis with bacterial colonies were also observed. The bacterial colonies observed histologically were immunohistochemically positive for Escherichia coli antigens. Escherichia coli was isolated from the organ samples from each outbreak. At least two E. coli isolates were serotyped as O18 and O161, which differed from the popular serotypes in Japan. These results suggest that avian pathogenic E. coli of uncommon serotypes can be imported from outside countries by infected chicks. Colibacillosis should be included in the differential diagnosis when meningitis is histologically observed in chicks.
authors.affiliation: A Pathological and Physiochemical Examination Division, Laboratory Department, Animal Quarantine Service, 11-1 Haramachi, Isogo, Yokohama, Kanagawa 235-0008, Japan.
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Kasuya
authors.affiliation: A Pathological and Physiochemical Examination Division, Laboratory Department, Animal Quarantine Service, 11-1 Haramachi, Isogo, Yokohama, Kanagawa 235-0008, Japan.
authors.forename: Natsumi
authors.initials: N
authors.lastname: Shimokubo
authors.affiliation: A Pathological and Physiochemical Examination Division, Laboratory Department, Animal Quarantine Service, 11-1 Haramachi, Isogo, Yokohama, Kanagawa 235-0008, Japan.
authors.forename: Chieko
authors.initials: C
authors.lastname: Kosuge
authors.affiliation: B Microbiological Examination Division, Laboratory Department, Animal Quarantine Service, 11-1 Haramachi, Isogo, Yokohama, Kanagawa 235-0008, Japan.
authors.forename: Kou
authors.initials: K
authors.lastname: Takayama
authors.affiliation: C Kagoshima Airport Moji Sub-Branch, Animal Quarantine Service, 1590-5 Kareigawa, Hayatocho, Kirishima, Kagoshima 899-5113, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Yoshida
authors.affiliation: D Exotic Disease Inspection Division, Laboratory Department, Animal Quarantine Service, Chubu Diagnostic Center, 1-2 Centrair, Tokoname, Aichi 479-0881, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Osaka
mesh_terms: D000818:Animals; D002645:Chickens / Q000821:virology; D004926:Escherichia coli / Q000302:isolation & purification*; D007564:Japan; D020814:Meningitis, Escherichia coli / Q000191:economics / Q000382:microbiology / Q000662:veterinary*; D011201:Poultry Diseases / Q000191:economics / Q000382:microbiology*
keywords: Escherichia coli; chicks; histopathology; meningitis