title: A Student's Guide to Giant Viruses Infecting Small Eukaryotes: From Acanthamoeba to Zooxanthellae.
abstract: The discovery of infectious particles that challenge conventional thoughts concerning "what is a virus" has led to the evolution a new field of study in the past decade. Here, we review knowledge and information concerning "giant viruses", with a focus not only on some of the best studied systems, but also provide an effort to illuminate systems yet to be better resolved. We conclude by demonstrating that there is an abundance of new host-virus systems that fall into this "giant" category, demonstrating that this field of inquiry presents great opportunities for future research.
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. wilhelm@utk.edu.
authors.forename: Steven W
authors.initials: SW
authors.lastname: Wilhelm
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. jbird9@tennessee.edu.
authors.forename: Jordan T
authors.initials: JT
authors.lastname: Bird
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. kbonifer@tennessee.edu.
authors.forename: Kyle S
authors.initials: KS
authors.lastname: Bonifer
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. bcalfee@tennessee.edu.
authors.forename: Benjamin C
authors.initials: BC
authors.lastname: Calfee
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. Tchen18@tennessee.edu.
authors.forename: Tian
authors.initials: T
authors.lastname: Chen
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. srose16@utk.edu.
authors.forename: Samantha R
authors.initials: SR
authors.lastname: Coy
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. pgainer@utk.edu.
authors.forename: P Jackson
authors.initials: PJ
authors.lastname: Gainer
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. egann@tennessee.edu.
authors.forename: Eric R
authors.initials: ER
authors.lastname: Gann
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. hheather@tennessee.edu.
authors.forename: Huston T
authors.initials: HT
authors.lastname: Heatherly
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. jlee175@tennessee.edu.
authors.forename: Jasper
authors.initials: J
authors.lastname: Lee
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. xliang5@tennessee.edu.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Liang
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. jliu36@tennessee.edu.
authors.forename: Jiang
authors.initials: J
authors.lastname: Liu
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. amitch51@tennessee.edu.
authors.forename: April C
authors.initials: AC
authors.lastname: Armes
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. mmoniruz@tennessee.edu.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Moniruzzaman
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. jrice18@utk.edu.
authors.forename: J Hunter
authors.initials: JH
authors.lastname: Rice
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. jstough@tennessee.edu.
authors.forename: Joshua M A
authors.initials: JM
authors.lastname: Stough
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. rtams@tennessee.edu.
authors.forename: Robert N
authors.initials: RN
authors.lastname: Tams
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. ewilli99@tennessee.edu.
authors.forename: Evan P
authors.initials: EP
authors.lastname: Williams
authors.affiliation: The Department of Microbiology, The University of Tennessee, Knoxville, TN 37996, USA. glecleir@tennessee.edu.
authors.forename: Gary R
authors.initials: GR
authors.lastname: LeCleir
mesh_terms: D056890:Eukaryota / Q000821:virology*; D000072139:Giant Viruses / Q000302:isolation & purification*
keywords: Mimiviridae; giant viruses; nucleocytoplasmic large DNA viruses (NCLDVs)