title: Efficacy of Activated 3X Platelet-Rich Plasma in the Treatment of Androgenic Alopecia.
abstract: BACKGROUND
  Platelet-rich plasma (PRP) has shown remarkable beneficial effects without any major adverse reactions in the treatment of androgenic alopecia .The growth factors in activated autologous PRP induces the proliferation of dermal papilla cells.
  
  
  OBJECTIVE
  To investigate the clinical efficacy of Platelet Rich Plasma prepared using Merisis One Step Gel Separation Technology in treatment of androgenic alopecia.
  
  
  METHODS
  Five patients were given autologous PRP injections on the affected area of alopecia over a period of three months at interval of two - three weeks and results were assessed.
  
  
  RESULTS
  Three months after the treatment, the patients presented clinical improvement in the hair counts, hair thickness, hair root strength and overall alopecia.
  
  
  CONCLUSIONS
  PRP appears to be a cheap, effective and promising therapy for androgenic alopecia with no major adverse effects.
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Rani
authors.initials: R
authors.lastname: James
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Rosy
authors.initials: R
authors.lastname: Chetry
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Vignesh
authors.initials: V
authors.lastname: Subramanian
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Ashtekar
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Nandagiri
authors.initials: N
authors.lastname: Srikruthi
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Sankar
authors.initials: S
authors.lastname: Ramachandran
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Prasad S
authors.initials: PS
authors.lastname: Koka
authors.affiliation: Merisis Therapeutics, DiponEd BioIntelligence, Bangalore, Karnataka, India.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Deb
mesh_terms: D000328:Adult; D000505:Alopecia / Q000628:therapy*; D001792:Blood Platelets / Q000166:cytology; D016207:Cytokines / Q000032:analysis; D004912:Erythrocytes / Q000166:cytology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D053657:Platelet-Rich Plasma / Q000378:metabolism*; D016896:Treatment Outcome
chemical_list: D016207:Cytokines; D036341:Intercellular Signaling Peptides and Proteins