title: To cleave or not to cleave: therapeutic gene editing with and without programmable nucleases.
authors.affiliation: ETAGEN Pharma, Inc., Cambridge, Massachusetts 01239, USA.
authors.forename: Tod M
authors.initials: TM
authors.lastname: Woolf
authors.affiliation: Mouse Engineering Core Facility, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.
authors.forename: Channabasavaiah B
authors.initials: CB
authors.lastname: Gurumurthy
authors.affiliation: Massachusetts General Hospital, Cambridge, Massachusetts 02139, USA.
authors.forename: Frederick
authors.initials: F
authors.lastname: Boyce
authors.affiliation: Gene Editing Institute for Translational Cancer Research, Helen F. Graham Cancer Center, and Research Institute, Newark, Delaware 19713, USA.
authors.forename: Eric B
authors.initials: EB
authors.lastname: Kmiec
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic / Q000379:methods*; D003851:Deoxyribonucleases / Q000235:genetics*; D000072669:Gene Editing / Q000379:methods*; D005818:Genetic Engineering / Q000379:methods; D006801:Humans
chemical_list: D003851:Deoxyribonucleases