title: Biomechanical analysis of stiffness and fracture displacement after using PMMA-augmented sacroiliac screw fixation for sacrum fractures.
abstract: Cement augmentation of pedicle screws is the gold standard for the stabilization of osteoporotic fractures of the spine. In-screw cement augmentation, in which cement is injected through the cannula, is another option for fracture stabilization of fragility fractures of the sacrum. However, biomechanical superiority of this technique compared to conventional sacroiliac screw fixation has not been tested. The present study compares the stability of cement-augmented and non-cement-augmented sacroiliac screw fixation in osteoporotic sacrum fractures under cyclic loading. Eight human donor pelvises with intact ligaments and 5th lumbar vertebra were dissected. A vertical shear fracture was created as a combination of a sacrum fracture and cutting of the symphysis. Both sides were tested in a single-limb-stance setup with 10,000 loading cycles applied. Stiffness of the pelvis and displacement of the fracture were measured using a hydraulic testing machine and a 3D image correlation system. The augmented screw fixation failed in two of eight pelvises, and the non-augmented screws failed in three of eight pelvises. CT scans showed no leakage of cement. In-screw polymethylmethacrylate (PMMA) augmentation showed no advantage based on measured displacement of the sacrum fractures or stiffness for sacroiliac screw fixation of fragility fractures of the sacrum.
authors.affiliation: .
authors.forename: Andreas
authors.initials: A
authors.lastname: Höch
authors.affiliation: .
authors.forename: Richard
authors.initials: R
authors.lastname: Schimpf
authors.affiliation: .
authors.forename: Niels
authors.initials: N
authors.lastname: Hammer
authors.affiliation: .
authors.forename: Stefan
authors.initials: S
authors.lastname: Schleifenbaum
authors.affiliation: .
authors.forename: Michael
authors.initials: M
authors.lastname: Werner
authors.affiliation: .
authors.forename: Christoph
authors.initials: C
authors.lastname: Josten
authors.affiliation: .
authors.forename: Jörg
authors.initials: J
authors.lastname: Böhme
mesh_terms: D001843:Bone Cements / Q000378:metabolism* / Q000627:therapeutic use; D001863:Bone Screws; D006801:Humans; D008159:Lumbar Vertebrae / Q000502:physiology*; D058866:Osteoporotic Fractures / Q000503:physiopathology / Q000601:surgery*; D010388:Pelvis / Q000502:physiology*; D019904:Polymethyl Methacrylate; D012447:Sacrum; D016103:Spinal Fractures / Q000503:physiopathology* / Q000601:surgery*; D013314:Stress, Mechanical
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate
keywords: PMMA; biomechanical analysis; fragility fracture; osteoporosis; pelvic fracture; sacroiliac screw fixation