title: [Assessment of Efficacy and Safety of Metabolic Therapy With Trimetazidine MB in Patients With Ischemic Heart Disease and Chronic Heart Failure].
abstract: Study purpose - to assess clinical and hemodynamic parameters in patients with ischemic heart disease (IHD) with and without use of metabolic therapy with trimetazidine MB.
  
  
  METHODS
  Seventy four patients with IHD, 40 of whom in addition to the main therapy for 3 months received metabolic preparation trimetazidine MB.
  
  
  RESULTS
  Number of anginal attacks and inhalations of nitroglycerin significantly decreased and parameters of hemodynamics improved after 3 months in patients who received trimetazidine MB.
  
  
  CONCLUSIONS
  Long-term use of trimetazidine MB in patients with IHD is advisable.
authors.affiliation: 1Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia; 2Nizhny Novgorod Cardiac Surgery Center Corll, Nizhny Novgorod, Russia.
authors.forename: M L
authors.initials: ML
authors.lastname: Gorbunova
authors.affiliation: 1Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia; 2Nizhny Novgorod Cardiac Surgery Center Corll, Nizhny Novgorod, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Vilkova
mesh_terms: D002908:Chronic Disease; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy*; D014292:Trimetazidine / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents; D014292:Trimetazidine