title: [Association Between T455C Polymorphism of Apolipoprotein C-III Gene, Insulin Resistance and Metabolic Syndrome Components].
abstract: OBJECTIVE
  to study an association between T455C apolipoprotein C-III (apo C-III) gene polymorphism, insulin resistance (IR), metabolic syndrome (MS) and its components in a Kyrgyz ethnic group.
  
  
  METHODS
  259 persons: 162 patients with MS and 97 sex and age matched controls without MS, diabetes mellitus and cardiovascular diseases were included in the study. Clinical examination with arterial blood pressure, anthropometric data measurement and laboratory tests for blood glucose and lipid parameters were performed in all included persons. In 140 patients test for immunoreactive serum insulin was done. DNA was extracted from blood cells and T455C polymorphism.
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: O S
authors.initials: OS
authors.lastname: Lunegova
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: A S
authors.initials: AS
authors.lastname: Kerimkulova
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: A E
authors.initials: AE
authors.lastname: Mirrakhimov
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: Yu V
authors.initials: YV
authors.lastname: Zalesskaya
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: M P
authors.initials: MP
authors.lastname: Nabiev
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: S S
authors.initials: SS
authors.lastname: Abilova
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: K V
authors.initials: KV
authors.lastname: Neronova
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: Zh T
authors.initials: ZT
authors.lastname: Isakova
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: A A
authors.initials: AA
authors.lastname: Aldashev
authors.affiliation: 1M. Mirrahimovs National Center of Cardiology and Therapy, Bishkek, Kirgizstan; 2I. Ahunbaevas Kyrgyz State Medical Academy, Bishkek, Kirgizstan; 3Interdepartmental Research Institute of Molecular Biology and Medicine.
authors.forename: E M
authors.initials: EM
authors.lastname: Mirrakhimov