title: Isolated and Combined Valve Surgery in Elderly Patients: A Comparison of Mid-Term Results.
abstract: BACKGROUND
  This study examined mid-term outcomes of valve surgery in the elderly, and focused on the difference in outcomes between isolated and combined valve surgery.
  
  
  METHODS
  From January 2012 to June 2016, 113 consecutive patients aged 75 years and older underwent valve surgery. In all, 60 underwent isolated valve surgery (Group I), and 53 underwent combined valve surgery (Group C) involving the combination of any valve procedures or valve surgery with concurrent other procedure. Short- and mid-term outcomes were compared between the two groups.
  
  
  RESULTS
  There was no significant difference in length of intensive care unit stay (2.8 days in Group S vs. 4.2 days in Group C, p = 0.08), hospital stay (16.2 vs. 18.7 days, p = 0.22), and mechanical ventilation (11.2 vs. 15.0 hours, p = 0.28). Neither was there any significant difference in operative mortality (1.6% vs. 5.6%, p = 0.25) nor morbidity (8.3% vs. 9.4%, p = 0.83) between the two groups. Actuarial survival rates at 1 and 3 years were 98.3% in Group S and 92.0% in Group C (log-rank p = 0.126).
  
  
  CONCLUSIONS
  Once patients have tolerated combined surgery during the early postoperative period, good survival rates equaling those of isolated valve surgery can be expected.
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Fumiya
authors.initials: F
authors.lastname: Yoneyama
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Chiho
authors.initials: C
authors.lastname: Tokunaga
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Enomoto
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Kisato
authors.initials: K
authors.lastname: Mitomi
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Sakamoto
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hiramatsu
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000401:mortality; D005260:Female; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D006351:Heart Valves / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007564:Japan; D053208:Kaplan-Meier Estimate; D008297:Male; D011183:Postoperative Complications / Q000401:mortality / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
keywords: combined valve surgery; elderly patients; isolated valve surgery