title: Hereditary hemorrhagic telangiectasia patient presenting with brain abscess due to silent pulmonary arteriovenous malformation.
abstract: Hereditary hemorrhagic telangiectasia is a rare autosomal dominant inherited disease that is usually complicated by visceral vascular malformations. Patients harboring such malformations are at increased risk of brain abscess formation, which despite advances in diagnostic and surgical methods remains a life threatening medical emergency with high mortality and morbidity rates. In the present report we describe a case of cerebral abscess due to silent pulmonary arteriovenous malformation (AVM) in a young patient previously undiagnosed for hereditary hemorrhagic telangiectasia syndrome (HHT).
authors.affiliation: Department of Neurosurgery, Children's Hospital "Agia Sofia", Athens, Greece.
authors.forename: Marios
authors.initials: M
authors.lastname: Themistocleous
authors.affiliation: Department of Neurosurgery, University of Athens Medical School, "Evangelismos" General Hospital, Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Giakoumettis
authors.affiliation: Department of Neurosurgery, Children's Hospital "Agia Sofia", Athens, Greece.
authors.forename: Andreas
authors.initials: A
authors.lastname: Mitsios
authors.affiliation: Department of Neurosurgery, University of Athens Medical School, "Evangelismos" General Hospital, Athens, Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Anagnostopoulos
authors.affiliation: Department of Neurosurgery, University of Athens Medical School, "Evangelismos" General Hospital, Athens, Greece.
authors.forename: Aristoteles
authors.initials: A
authors.lastname: Kalyvas
authors.affiliation: Department of Neurosurgery, University of Athens Medical School, "Evangelismos" General Hospital, Athens, Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Koutsarnakis
mesh_terms: D000328:Adult; D001165:Arteriovenous Malformations / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics*; D001922:Brain Abscess / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics*; D003937:Diagnosis, Differential; D006801:Humans; D008168:Lung / Q000098:blood supply*; D008279:Magnetic Resonance Imaging; D008297:Male; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics*; D014057:Tomography, X-Ray Computed
keywords: Hereditary hemorrhagic teleangiectasia; arteriovenous malformation; brain abscess