title: Vinegar consumption can attenuate postprandial glucose and insulin responses; a systematic review and meta-analysis of clinical trials.
abstract: OBJECTIVE
  Postprandial hyperglycemia plays a decisive role in the development of chronic metabolic disorders. The effect of vinegar intake with a meal on postprandial glucose has been studied in several trials with conflicting results.
  
  
  METHODS
  The purpose of the current study was to systematically review control trials that report on the effect of vinegar intake on postprandial glucose response. Postprandial insulin response was considered as secondary outcome.
  
  
  RESULTS
  The pooled analysis of studies revealed a significant mean glucose and insulin area under the curve (AUC) reduction in participants who consumed vinegar compared with the control group (standard mean difference=-0.60, 95%CI -1.08 to -0.11, p=0.01 and -1.30, 95%CI -1.98 to -0.62, p<0.001, respectively).
  
  
  CONCLUSIONS
  The findings suggest that vinegar can be effective in reducing postprandial glucose and insulin levels, indicating it could be considered as an adjunctive tool for improving glycemic control.
authors.affiliation: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Farideh
authors.initials: F
authors.lastname: Shishehbor
authors.affiliation: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: Mansoori_anahita@yahoo.com.
authors.forename: Anahita
authors.initials: A
authors.lastname: Mansoori
authors.affiliation: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Shirani
mesh_terms: D019342:Acetic Acid / Q000627:therapeutic use*; D001786:Blood Glucose / Q000378:metabolism*; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy; D007328:Insulin / Q000378:metabolism*; D008297:Male; D019518:Postprandial Period / Q000502:physiology*
chemical_list: D001786:Blood Glucose; D007328:Insulin; D019342:Acetic Acid
keywords: Acetic acid; Glucose; Insulin; Postprandial; Vinegar