title: Echocardiographic Assessment of Right Ventricular Size and Function in Cats With Hypertrophic Cardiomyopathy.
abstract: BACKGROUND
  Studies evaluating right ventricular (RV) structural and functional abnormalities in feline hypertrophic cardiomyopathy (HCM) are limited.
  
  
  OBJECTIVE
  Right ventricular structural and functional abnormalities are present in cats with HCM and are associated with clinical severity.
  
  
  METHODS
  Eighty-one client-owned cats.
  
  
  METHODS
  Retrospective 2-dimensional (2D) echocardiographic study. Right atrial diameter (RAD), RV free wall thickness (RVFWd), RV internal dimension (RVIDd), RV fractional area change (FAC), and tricuspid annular plane systolic excursion (TAPSE) were measured in control cats (n = 26), cats with subclinical HCM (subclinical HCM; n = 31), and cats with HCM and congestive heart failure (HCM + CHF; n = 24).
  
  
  RESULTS
  Right heart size (RAD, RVFWd, and RVIDd) and RV function (FAC and TAPSE) significantly (all P < .05) increased and decreased, respectively, in the HCM + CHF group compared with controls. In the subclinical HCM group, only RVFWd was significantly (P < .05) higher than in controls. Compared with reference intervals derived from controls, 29% of cats with HCM had increased RVFWd. Increased left ventricular free wall thickness, increased RVIDd and decreased TAPSE independently correlated with increased left atrial size. Cats with HCM and pleural effusion were significantly more likely to have increased RVFWd and had increased RAD and decreased TAPSE compared with cats without pleural effusion.
  
  
  CONCLUSIONS
  Right ventricular remodeling and dysfunction occur in some cats with HCM and may be associated with clinical severity. Our results support involvement of RV in the pathophysiology of HCM in some cats and support echocardiographic assessment of the RV in cats with HCM.
authors.affiliation: Department of Medicine & Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, CA.
authors.forename: L C
authors.identifier: http://orcid.org/0000-0002-3563-0737
authors.initials: LC
authors.lastname: Visser
authors.affiliation: Department of Medicine & Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, CA.
authors.forename: C Q
authors.initials: CQ
authors.lastname: Sloan
authors.affiliation: Department of Medicine & Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, CA.
authors.forename: J A
authors.initials: JA
authors.lastname: Stern
mesh_terms: D000818:Animals; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging / Q000662:veterinary*; D002371:Cat Diseases / Q000000981:diagnostic imaging*; D002415:Cats; D004452:Echocardiography / Q000662:veterinary; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D008297:Male; D011237:Predictive Value of Tests
keywords: Echocardiography; Feline; Right heart; Right ventricular hypertrophy