title: Six Out of Ten Women with Recurrent Urinary Tract Infections Complain of Distressful Sexual Dysfunction - A Case-Control Study.
abstract: Uncomplicated recurrent urinary tract infections (rUTIs) are common among reproductive-aged women. We aimed to assess the prevalence and predictors of sexual dysfunction (FSD) in a cohort of women with rUTIs and compare their psychometric scores to those of matched controls. Data from 147 rUTIs women and 150 healthy controls were analysed. Participants completed the International Prostatic Symptoms Score (IPSS), the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (SDS). Descriptive statistics and logistic regression models tested prevalence and predictors of distressful FSD. Women with rUTIs had lower FSFI scores (p < 0.001) and a greater proportion of pathological FSFI (78.9% vs. 21.4%; p < 0.001) and SDS scores (77.8% vs. 21.4%; p < 0.001) than controls. Of rUTIs patients, 88 (60%), 77 (52.2%), and 75 (51.1%) reported pathological scores for FSFI-pain, lubrication and arousal, respectively; moreover, 64% had concomitant pathological FSFI and SDS scores. Age, IPSS severity, rUTIs, a history of ≥6 UTIs/year and a history of constipation were independent predictors of pathologic FSFI and SDS (all p ≤ 0.05). In conclusion, up to 80% of women with rUTIs showed pathologic FSFI and SDS scores, with 60% reporting scores suggestive of distressful FSD. Having ≥6 UTIs/year and a history of constipation independently predicted distressful FSD.
authors.affiliation: Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milan, 20132, Italy.|Department of Urology, IRCCS Fondazione Ca' Granda - Ospedale Maggiore Policlinico; Milan, 20122, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Boeri
authors.affiliation: Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milan, 20132, Italy.|University Vita-Salute San Raffaele, Milan, 20132, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Capogrosso
authors.affiliation: Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milan, 20132, Italy.|University Vita-Salute San Raffaele, Milan, 20132, Italy.
authors.forename: Eugenio
authors.initials: E
authors.lastname: Ventimiglia
authors.affiliation: Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milan, 20132, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Scano
authors.affiliation: Ospedale San Raffaele Resnati, Milan, 20132, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Graziottin
authors.affiliation: Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milan, 20132, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Dehò
authors.affiliation: Department of Urology, IRCCS Fondazione Ca' Granda - Ospedale Maggiore Policlinico; Milan, 20122, Italy.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Montanari
authors.affiliation: Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milan, 20132, Italy.|University Vita-Salute San Raffaele, Milan, 20132, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Montorsi
authors.affiliation: Division of Experimental Oncology/Unit of Urology; URI; IRCCS Ospedale San Raffaele, Milan, 20132, Italy.|University Vita-Salute San Raffaele, Milan, 20132, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Salonia
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D011594:Psychometrics; D012307:Risk Factors; D012725:Sexual Behavior; D020018:Sexual Dysfunctions, Psychological / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D011795:Surveys and Questionnaires; D014552:Urinary Tract Infections / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*