title: When Does Organic Chemistry Follow Nature's Lead and "Make the Switch"?
abstract: The case is made for transitioning organic chemistry from a developed discipline that remains highly dependent upon organic solvents to one that will be sustainable, based on water as the reaction medium. Processes in hand that today achieve the same bond constructions characteristic of traditional organic synthesis, but can be accomplished under environmentally responsible conditions, are discussed as representative of the potential that lies ahead.
authors.affiliation: Department of Chemistry & Biochemistry University of California , Santa Barbara, California 93106, United States.
authors.forename: Bruce H
authors.identifier: 0000-0001-9116-7049
authors.initials: BH
authors.lastname: Lipshutz
mesh_terms: D002384:Catalysis; D002625:Chemistry, Organic; D020285:Cryoelectron Microscopy; D046529:Microscopy, Electron, Transmission; D019368:Nature