title: Tertiary amine self-catalyzed intramolecular Csp3-H functionalization with in situ generated allenes for the formation of 3-alkenyl indolines.
abstract: A novel methodology for the synthesis of 3-alkenyl indolines through the reaction of in situ generated allenes with N-benzylic Csp3-H has been developed. The reaction was realized by Pd(0) catalyzed allenylation of propargyl carbonate with organoboron and subsequent tertiary amine self-catalyzed Csp3-H functionalization in a one-pot process. Control reactions suggested that the substrate itself might also serve as a Lewis base for the N-benzylic Csp3-H functionalization.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China. yzli@chem.ecnu.edu.cn.
authors.forename: Yulei
authors.identifier: http://orcid.org/0000-0002-8628-2680
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China. yzli@chem.ecnu.edu.cn.
authors.forename: Murong
authors.initials: M
authors.lastname: Xu
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China. yzli@chem.ecnu.edu.cn.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Zheng
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China. yzli@chem.ecnu.edu.cn.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yuan
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China. yzli@chem.ecnu.edu.cn.
authors.forename: Yanzhong
authors.identifier: http://orcid.org/0000-0002-2898-3075
authors.initials: Y
authors.lastname: Li