title: A giant aneurysm of noncoronary sinus of Valsalva concomitant with aortic regurgitation and mitral regurgitation.
abstract: Aneurysms of the sinus of Valsalva (ASV) are rare, with an incidence ranging from 0.1% to 3.5% of all congenital cardiac defects and a prevalence of 0.009% in an autopsy series.ASVs occur much more frequently in the right coronary sinus of Valsalva. Previous reports, based on necropsy and cardiac surgery findings, estimated that 20% of ASVs are unruptured. Patients with an unruptured ASV may remain asymptomatic for a long period of time until rupture. They may also presented with dyspnea, palpitation, and angina-like chest pain. Aortic insufficiency in the patients with unruptured ASVs is common, and other valvular lesions can be observed in these patients as well. Echocardiography, as a noninvasive and portable tool, is widely used to detect ASVs. Additionally, computed tomography and cardiac magnetic resonance imaging, alone or in combination, can provide precise information about its anatomic extension and intrinsic characteristics of the pathology.
authors.affiliation: Department of Cardiovascular Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Luo
authors.affiliation: Department of Cardiovascular Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Fang
authors.affiliation: Department of Cardiovascular Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors.forename: Wei
authors.identifier: http://orcid.org/0000-0002-3156-1228
authors.initials: W
authors.lastname: Meng
mesh_terms: D001014:Aortic Aneurysm / Q000000981:diagnostic imaging* / Q000209:etiology*; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging* / Q000209:etiology*; D057791:Cardiac Imaging Techniques / Q000379:methods; D003937:Diagnosis, Differential; D004452:Echocardiography / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000209:etiology*; D012850:Sinus of Valsalva / Q000000981:diagnostic imaging*
keywords: Valsalva; aneurysm; aortic regurgitation; mitral; regurgitation; sinus of Valsalva