title: Emerging trends and new developments in monoclonal antibodies: A scientometric analysis (1980-2016).
abstract: This article aims to explore the intellectual landscape of the study of monoclonal antibody (mAb), mainly to identify thematic trends, landmark articles and emerging trends involving mAb. This work is based on 4 sets of bibliographic records retrieved from the Web of Science. The final data set, consisting of 7,385 bibliographic records, was combined from the 4 individual data sets. This study explores the document co-citation clusters of 7,385 bibliographic records to identify the origin of mAb and the hot research specialty of this domain by applying CiteSpace software. We examined the mAb evolution from 4 perspectives: (1) Clusters of cited references regarding mAb; (2) Cited authors as contributors to mAb research; (3) Institutions participating in mAb research; and (4) Cited journals regarding mAb. The technical development, drug development and clinical applications of mAbs were analyzed. Through data analysis, we have identified the new directions for the exploration of mAbs, interactions between mAb technologies and diseases, and evolving global collaboration among institutions.
authors.affiliation: a State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau , Macao.
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Lai
authors.affiliation: a State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau , Macao.
authors.forename: Ruibing
authors.initials: R
authors.lastname: Wang
authors.affiliation: a State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau , Macao.
authors.forename: Xin
authors.initials: X
authors.lastname: Chen
authors.affiliation: b School of Economics and Management, Beijing Jiaotong University , Beijing , China.
authors.forename: Daisheng
authors.initials: D
authors.lastname: Tang
authors.affiliation: a State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau , Macao.
authors.forename: Yuanjia
authors.initials: Y
authors.lastname: Hu
authors.affiliation: a State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau , Macao.
authors.forename: Jing
authors.initials: J
authors.lastname: Cai
authors.affiliation: a State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau , Macao.
authors.forename: Qingwen
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: a State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau , Macao.
authors.forename: Hao
authors.initials: H
authors.lastname: Hu
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000302:isolation & purification* / Q000627:therapeutic use*; D015706:Bibliometrics; D035843:Biomedical Research / Q000639:trends; D055808:Drug Discovery / Q000639:trends*; D006801:Humans; D007155:Immunologic Factors / Q000302:isolation & purification* / Q000627:therapeutic use*
chemical_list: D000911:Antibodies, Monoclonal; D007155:Immunologic Factors
keywords: CiteSpace; intellectual landscape; mAb; monoclonal antibody; scientometric