title: [Estimates of Target Population for Pneumococcal Vaccination in People over 50 years in Catalonia and Spain].
abstract: OBJECTIVE
  Published data about prevalence of distinct risk condictions for pneumococcal disease is scarce. This study investigated the prevalence of distinct risk conditions for pneumococal disease in Catalonian adults and stimated the potential size of target population for pneumococcal vaccination in Catalonia and Spain.
  
  
  METHODS
  Cross-sectional population-based study that included 2,033,465 individuals older than 49 years-old assigned to the Catalonian Health Institute (Catalonia, Spain) at 01/01/2015. The Catalonian Health Institute Information System for the Development of Research in Primary Care (SIDIAP) was used to identify comorbidities and/or underlying conditions in each subject and establish potential target population for pneumococcal vaccination on the basis of their risk for suffering pneumococcal infections: 1) immunocompromised subjects; 2) immunocompetents subjects with any risk condition; 3) immunocompetents subjects without risk conditions.
  
  
  RESULTS
  Of the 2,033,465 study subjects, 1,053,155 (51.8%) had no risk conditions, 649,014 (31.9%) had one risk condition and 331,296 (16.3%) had multiple risk conditions (11.4% in 50-64 years vs 21.2% in people older than 65 years, p smaller than 0.001; 21.8% in men vs 11.6% in women, p smaller than 0.001). Overall, 176,600 (8.7%) and 803,710 (39.5%) were classified in risk stratum 1 and 2, respectively. According to distinct risk strata considered, the target population for pneumococcal vaccination varied between 0.2-1.9 million in Catalonia and 1.5-2.3 million in Spain.
  
  
  CONCLUSIONS
  In our setting, almost fifty percent of people ≥50 years have at least one risk condition to suffert pneumococcal disease. Adult population susceptible for pneumococal vaccination largely varies depending on the risk stratum considered as targeted people for pneumococcal vaccination.
authors.affiliation: Direcció d'Atenció Primària Camp de Tarragona. Institut Català de la Salut. Tarragona. España.
authors.forename: Angel
authors.initials: A
authors.lastname: Vila-Córcoles
authors.affiliation: Direcció d'Atenció Primària Camp de Tarragona. Institut Català de la Salut. Tarragona. España.
authors.forename: Olga
authors.initials: O
authors.lastname: Ochoa-Gondar
authors.affiliation: Direcció d'Atenció Primària Camp de Tarragona. Institut Català de la Salut. Tarragona. España.
authors.forename: Eva
authors.initials: E
authors.lastname: Satué
authors.affiliation: Direcció d'Atenció Primària Camp de Tarragona. Institut Català de la Salut. Tarragona. España.
authors.forename: Cinta
authors.initials: C
authors.lastname: de Diego
authors.affiliation: Universitat Rovira i Virgili. Tarragona, España.
authors.forename: Marc
authors.initials: M
authors.lastname: Vila-Rovira
authors.affiliation: Sistemas de Información. Hospital Universitario Joan XXIII. Institut Català de la Salut. Tarragona. España.
authors.forename: Manel
authors.initials: M
authors.lastname: Jariod
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D020380:Needs Assessment; D011008:Pneumococcal Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D022242:Pneumococcal Vaccines; D018570:Risk Assessment; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D022242:Pneumococcal Vaccines
keywords: 13-valent pneumococcal vaccine [Supplementary Concept]; Adults; Pneumococcal Vaccines; Pneumococcal infection; Pneumonia, Pneumococcal ; Prevalence; Risk factors; Spain; Target population