title: The fate of oocyte nuclear proteins during early development ofXenopus laevis.
abstract: The localization and movements of four nuclear proteins, originally contained in the germinal vesicle ofXenopus oocytes, were followed through early development from cleavage to late neurula. The study made use of monoclonal antibodies directed against germinal vesicle proteins. Biochemical methods showed that all proteins persist in the embryo without a change in molecular size or gross concentration. At early stages the proteins are localized preferentially in the cytoplasm of the animal hemisphere. They shift from the cytoplasm to the nucleus at stages specific for the individual proteins. During mitosis the proteins are released from the nucleus into the cytoplasm.
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstraße 35, D-7400, Tübingen, Federal Republic of Germany.
authors.forename: Christine
authors.initials: C
authors.lastname: Dreyer
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstraße 35, D-7400, Tübingen, Federal Republic of Germany.
authors.forename: Elke
authors.initials: E
authors.lastname: Scholz
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstraße 35, D-7400, Tübingen, Federal Republic of Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Hausen
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstraße 35, D-7400, Tübingen, Federal Republic of Germany.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Gläser
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstraße 35, D-7400, Tübingen, Federal Republic of Germany.
authors.forename: Ursula
authors.initials: U
authors.lastname: Müller
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstraße 35, D-7400, Tübingen, Federal Republic of Germany.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Siegel
keywords: Embryogenesis; Monoclonal antibody; Oocyte nuclear proteins; Xenopus laevis