title: [Early Systolic Dysfunction of Left Ventricular Myocardium Is Reflected On Electrocardiogram of Patients With Aortic Stenosis].
abstract: to study relation between electrocardiographic (ECG) criteria of left ventricular hypertrophy (LVH) and parameters of tissue Doppler (TD) and LV strain in patients with aortic stenosis (AS) with preserved LV ejection fraction.
  
  
  
  We examined 80 patients with degenerative AS of all degrees of severity. Examination included history, blood serum cholesterol and creatinine, 12 lead ECG, routine echocardiography (EchoCG), TD, and LV global longitudinal peak strain (GLPS) in apical positions of 2-dimensional EchoCG.
  
  
  
  ECG criteria demonstrated low sensitivity relative to presence of real LVH. Average values of TD and (GLPS) were lowered in patients with AS. Correlation analysis revealed reverse relationship between TD and GLPX (<0.05). ROC-curve analysis showed very good quality of informativeness of the Cornell index and product for diagnosis of GLPX lowering below - 13%.
  
  
  
  ECG criteria of LVH poorly reflect real LVH but are markers of early systolic LV dysfunction.
authors.affiliation: 1Central State Medical Academy, President Management Department RF, Moscow, Russia; 2City Clinical Hospital 17, Moscow, Russia; 3Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia; 4City Clinical Hospital 51, Moscow, Russia; 5Federal Research Clinical Center for specialized types of health care and medical technologies, Moscow, Russia.
authors.forename: O S
authors.initials: OS
authors.lastname: Chumakova
authors.affiliation: 1Central State Medical Academy, President Management Department RF, Moscow, Russia; 2City Clinical Hospital 17, Moscow, Russia; 3Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia; 4City Clinical Hospital 51, Moscow, Russia; 5Federal Research Clinical Center for specialized types of health care and medical technologies, Moscow, Russia.
authors.forename: T A
authors.initials: TA
authors.lastname: Tipteva
authors.affiliation: 1Central State Medical Academy, President Management Department RF, Moscow, Russia; 2City Clinical Hospital 17, Moscow, Russia; 3Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia; 4City Clinical Hospital 51, Moscow, Russia; 5Federal Research Clinical Center for specialized types of health care and medical technologies, Moscow, Russia.
authors.forename: M N
authors.initials: MN
authors.lastname: Alekhin
authors.affiliation: 1Central State Medical Academy, President Management Department RF, Moscow, Russia; 2City Clinical Hospital 17, Moscow, Russia; 3Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia; 4City Clinical Hospital 51, Moscow, Russia; 5Federal Research Clinical Center for specialized types of health care and medical technologies, Moscow, Russia.
authors.forename: L A
authors.initials: LA
authors.lastname: Zateishchikov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000503:physiopathology*; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D012372:ROC Curve; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000503:physiopathology*