title: The determination of sense organs in Drosophila: interaction of scute with daughterless.
abstract: Several genetic loci have been implicated in the formation of the peripheral nervous system during Drosophila embryogenesis. As a first step towards understanding the functional interrelationships between these genes, we have searched for dominant interactions between deficiencies for the achaete-scute complex (AS-C), daughterless (da) and six other regions necessary for peripheral neurogenesis in the embryo. We have found that adult flies doubly heterozygous for deletions of AS-C and of da, or of AS-C and a small region on the fourth chromosome, exhibit characteristic bristle defects, suggesting that these genes cooperate to form sense organs both in the embryo and in the adult.
authors.affiliation: Laboratoire de Génétique, Université Libre de Bruxelles, 67, rue des Chevaux, B. 1640, Rhode-St.-Genèse, Belgium.
authors.forename: Christine
authors.initials: C
authors.lastname: Dambly-Chaudière
authors.affiliation: Laboratoire de Génétique, Université Libre de Bruxelles, 67, rue des Chevaux, B. 1640, Rhode-St.-Genèse, Belgium.
authors.forename: Alain
authors.initials: A
authors.lastname: Ghysen
authors.affiliation: Howard Hugues Medical Institute and Departments of Physiology and Biochemistry, University of California, 94143, San Francisco, CA, USA.
authors.forename: Lily Yen
authors.initials: LY
authors.lastname: Jan
authors.affiliation: Howard Hugues Medical Institute and Departments of Physiology and Biochemistry, University of California, 94143, San Francisco, CA, USA.
authors.forename: Yuh Nung
authors.initials: YN
authors.lastname: Jan
keywords: Drosophila larva; Gene interactions; Peripheral neurogenesis; achaete-scute complex; daughterless