title: The Efficacy of Two Trabecular Bypass Stents Compared to One in the Management of Open-Angle Glaucoma.
abstract: To compare the outcomes of combined cataract surgery with two trabecular microbypass stents compared to one in patients with open-angle glaucoma.
  
  
  
  Patients with primary open-angle glaucoma were included. Primary outcome measures were intraocular pressure (IOP), postoperative medications, and postoperative adverse events.
  
  
  
  The average patient age was 73.2 years. Thirty-nine eyes had phacoemulsification and one stent implanted (Group 1); 30 eyes had phacoemulsification and two stents implanted (Group 2). A significant reduction in mean IOP from baseline to 12 months was noted for both Group 1 (16.67 ± 4.1 mm Hg to 14.45 ± 3.8 mm Hg; p < 0.0251) and Group 2 (18.33 ± 3.99 mm Hg to 14.31 ± 1.8 mm Hg; p < 0.0014). Group 2 had a greater percent decrease in IOP at 12 months than Group 1, but this difference was not statistically significant. Only Group 2 demonstrated a statistically significant reduction in medication burden at 12 months. There were no serious complications in either group thought to be caused by the microbypass stents.
  
  
  
  Both groups demonstrated a significant reduction in IOP at 12 months. Group 2 showed a greater percent decrease in IOP; however, it was not statistically significant. Only Group 2 demonstrated a statistically significant reduction in medication burden.
authors.affiliation: Department of Ophthalmology, Walter Reed National Military Medical Center,8901 Wisconsin Avenue, Bethesda, MD 20889.
authors.forename: Anton
authors.initials: A
authors.lastname: Vlasov
authors.affiliation: Department of Ophthalmology, Walter Reed National Military Medical Center,8901 Wisconsin Avenue, Bethesda, MD 20889.
authors.forename: Won I
authors.initials: WI
authors.lastname: Kim
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000071556:Cancellous Bone / Q000601:surgery*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D063868:Patient Outcome Assessment; D011446:Prospective Studies; D012189:Retrospective Studies; D015607:Stents / Q000592:standards*