title: Congenital hemangioma in spondylocostal dysostosis: a novel association.
abstract: Congenital hemangioma is a benign tumor caused by dysfunction in embryogenesis and vasculogenesis, which progresses during fetal life to manifest as fully developed at birth. Although hemangiomas are the most common tumor of infancy, rapidly involuting congenital hemangioma has not been described in spondylocostal dysostosis. I report the novel association of congenital hemangioma and spondylocostal dysostosis in a Mexican newborn female patient with neural tube defects. Given the embryological relationship between skin and nervous system, I surmise that this association is not coincidental. I also propose that these morphologic alterations be incorporated to the spondylocostal dysostosis phenotype and specifically looked for in other affected children, in order to provide appropriate medical management and genetic counseling.
authors.affiliation: Hospital General de Tijuana, Instituto de Servicios de Salud Pública en el Estado de Baja California - Baja California, México.
authors.forename: Victor Michael
authors.initials: VM
authors.lastname: Salinas-Torres
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006391:Hemangioma / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology; D006548:Hernia, Diaphragmatic / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008591:Meningomyelocele / Q000000981:diagnostic imaging / Q000473:pathology; D009423:Nervous System Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology; D009436:Neural Tube Defects / Q000000981:diagnostic imaging / Q000473:pathology; D012878:Skin Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology; D013904:Thoracic Vertebrae / Q000002:abnormalities / Q000000981:diagnostic imaging