title: Acute Liver Failure from Herpes Simplex Virus in an Immunocompetent Patient Due to Direct Inoculation of the Peritoneum.
abstract: Herpes simplex virus (HSV) hepatitis is a rare cause of acute liver failure (ALF). It carries a mortality rate of 80% if untreated, thus early identification and treatment are critical. Without high clinical suspicion, HSV hepatitis is difficult to diagnose. A 48-year-old Hispanic female presented with a 4-day history of abdominal pain and a vaginal cuff tear requiring laparoscopic repair. She subsequently developed postsurgical disseminated HSV, resulting in ALF. Acyclovir was initiated, but she was resistant to treatment. She was given additional foscarnet and responded without requiring a liver transplant.
authors.affiliation: Department of Internal Medicine, University of Louisville, Louisville, KY.
authors.forename: Dhruv
authors.initials: D
authors.lastname: Chaudhary
authors.affiliation: Department of Internal Medicine, University of Louisville, Louisville, KY.
authors.forename: Shifat
authors.initials: S
authors.lastname: Ahmed
authors.affiliation: Department of Internal Medicine, University of Louisville, Louisville, KY.
authors.forename: Nanlong
authors.initials: N
authors.lastname: Liu
authors.affiliation: Department of Gastroenterology and Hepatology, University of Louisville, Louisville, KY.
authors.forename: Luis
authors.initials: L
authors.lastname: Marsano-Obando