title: Iterative C-H Functionalization Leading to Multiple Amidations of Anilides.
abstract: Polyaminobenzenes were synthesized by the ruthenium-catalyzed iterative C-H amidation of anilides using dioxazolones as an amino source. This strategy could be implemented by the sequential activation of C-H bonds of formerly generated compounds by cascade chelation assistance of newly installed amide groups. Computational studies provided a rationale.
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.|Center for Catalytic Hydrocarbon Functionalization, Institute for Basic Science (IBS), Daejeon, 34141, Republic of Korea.
authors.forename: Juhyeon
authors.initials: J
authors.lastname: Park
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.|Center for Catalytic Hydrocarbon Functionalization, Institute for Basic Science (IBS), Daejeon, 34141, Republic of Korea.
authors.forename: Jia
authors.initials: J
authors.lastname: Lee
authors.forename: Carolyn
authors.lastname: Buckley
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.|Center for Catalytic Hydrocarbon Functionalization, Institute for Basic Science (IBS), Daejeon, 34141, Republic of Korea.
authors.forename: Sukbok
authors.initials: S
authors.lastname: Chang
keywords: C−H activation; amidation; arenes; reaction mechanisms; ruthenium