title: fs(1)K10, a germline-dependent female sterile mutation causing abnormal chorion morphology inDrosophila melanogaster.
abstract: Females homozygous for a newly isolated mutation induced by ethyl methane sulphonate,fs(1)K10, lay abnormally shaped eggs in which the dorsal appendages of the chorion are enlarged and fused ventrally. The eggs are usually not fertilized and development is never normal beyond the blastoderm stage. The mutant was mapped to the tip of the X-chromosome with a meiotic position of 1-0.5 and a cytological location between 2B17 and 3A3. Using germ line mosaics constructed by transplantation of pole cells, it was shown that the abnormal morphology and the sterility are obtained only when the germ line is homozygous for the mutant.
authors.affiliation: Zoological Institute, University of Zürich, Künstlergasse 16, CH-8006, Zürich, Switzerland.
authors.forename: Eric
authors.initials: E
authors.lastname: Wieschaus
authors.affiliation: Department of Biology, University of Virginia, 22901, Charlottesville, Virginia, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Marsh
authors.affiliation: Department of Cell Biology, Biozentrum der Universität, Klingelbergstraße 70, CH-4056, Basel, Switzerland.
authors.forename: Walter
authors.initials: W
authors.lastname: Gehring
keywords: Drosophila; Egg shape; Pole cell transplantation; Sterility