title: Seroprevalence for 2117-like vesiviruses in Italian household dogs.
abstract: In 2003, a novel calicivirus, the vesivirus (VeV) strain 2117, was identified incidentally as a contaminant in Chinese Hamster Ovary (CHO) cell cultures by a German pharmaceutical company. Similar contaminations have been documented in three additional episodes, in bio-reactors used for production of recombinant drugs. More, recently 2117-like VeVs have also been identified at high prevalence in the stools from asymptomatic kennel dogs and only sporadically in diarrhoeic and healthy household dogs. In this study, antibodies for 2117-like viruses were detected in 21.5% of sera from household dogs, indicating that they are common viruses in the canine host.
authors.affiliation: Faculty of Veterinary Medicine, Università degli Studi di Teramo, Italy. Electronic address: bdimartino@unite.it.
authors.forename: Barbara
authors.initials: B
authors.lastname: Di Martino
authors.affiliation: Faculty of Veterinary Medicine, Università degli Studi di Teramo, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Di Profio
authors.affiliation: Department of Veterinary Medicine, Università Aldo Moro di Bari, Valenzano, Italy.
authors.forename: Livia
authors.initials: L
authors.lastname: Bodnar
authors.affiliation: Faculty of Veterinary Medicine, Università degli Studi di Teramo, Italy.
authors.forename: Irene
authors.initials: I
authors.lastname: Melegari
authors.affiliation: Faculty of Veterinary Medicine, Università degli Studi di Teramo, Italy.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Sarchese
authors.affiliation: Azienda USL di Reggio Emilia, Reggio Emilia, Italy.
authors.forename: Ivano
authors.initials: I
authors.lastname: Massirio
authors.affiliation: Department of Veterinary Medicine, Università Aldo Moro di Bari, Valenzano, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Dowgier
authors.affiliation: Department of Veterinary Medicine, Università Aldo Moro di Bari, Valenzano, Italy.
authors.forename: Gianvito
authors.initials: G
authors.lastname: Lanave
authors.affiliation: Faculty of Veterinary Medicine, Università degli Studi di Teramo, Italy.
authors.forename: Fulvio
authors.initials: F
authors.lastname: Marsilio
authors.affiliation: Institute for Veterinary Medical Research, Centre for Agricultural Research, Budapest, Hungary.
authors.forename: Krisztián
authors.initials: K
authors.lastname: Bányai
authors.affiliation: Department of Veterinary Medicine, Università Aldo Moro di Bari, Valenzano, Italy.
authors.forename: Canio
authors.initials: C
authors.lastname: Buonavoglia
authors.affiliation: Department of Veterinary Medicine, Università Aldo Moro di Bari, Valenzano, Italy.
authors.forename: Vito
authors.initials: V
authors.lastname: Martella
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D016466:CHO Cells; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D003412:Cricetulus; D004283:Dog Diseases / Q000453:epidemiology* / Q000821:virology; D004285:Dogs; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005243:Feces / Q000821:virology; D007558:Italy / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D029342:Vesivirus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral
keywords: Antibodies; Chinese Hamster Ovary cells; Contaminants; Dogs; Strain 2117; Vesivirus