title: Translation and validation of the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire for the Brazilian Portuguese language.
abstract: Uterine fibroids (UF), also known as leiomyomas, are the most prevalent gynecological tumors. The Uterine Fibroid Symptoms and Quality of Life (UFS-QOL) is the only specific questionnaire that assesses symptom intensity and quality-of-life issues for women with symptomatic UF; however, it only exists in the English language. Thus, we aimed to translate and culturally validate the UFS-QOL questionnaire for the Brazilian Portuguese language.
  Cross-sectional study, Department of Gynecology and Obstetrics, FMRP-USP.
  113 patients with UF (case group) and 55 patients without UF (control group) were interviewed using the UFS-QOL questionnaire after translation and cultural adaptation. The Short Form-36 questionnaire was used as a control. Demographic and psychometric variables were analyzed.
  Women with UF presented higher mean age, body mass index, weight, parity and comorbidities than the control group (P < 0.05). The most prevalent complaints were abnormal uterine bleeding (93.8%), pelvic pain (36.3%) and extrinsic compression (10.6%) and these presented adequate construct validity regarding UFS-QOL severity (P < 0.05). The UFS-QOL questionnaire presented good internal consistency regarding symptom severity and quality-of-life-related domains (intraclass correlation coefficient, ICC = 0.82/0.88). Structural validity presented correlation coefficients ranging from 0.59 to 0.91. Test-retest comparison did not show differences among the UFS-QOL subscales. After treatment, women with UF presented improvements on all subscales.
  The UFS-QOL questionnaire presented adequate translation to the Brazilian Portuguese language, with good internal consistency, discriminant validity, construct validity, structural validity and responsiveness, along with adequate test-retest results.
authors.affiliation: MD, PhD. Attending Physician, Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto (FMRP), Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil.|Department of Gynecology and Obstetrics, School of Medicine, Universidade de Ribeirão Preto (UNAERP), Ribeirão Preto (SP), Brazil.
authors.forename: Luiz Gustavo
authors.initials: LG
authors.lastname: Oliveira Brito
authors.affiliation: MD, PhD. Attending Physician, Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto (FMRP), Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil.|Department of Gynecology and Obstetrics, School of Medicine, Universidade de Ribeirão Preto (UNAERP), Ribeirão Preto (SP), Brazil.
authors.forename: Daniela Alves
authors.initials: DA
authors.lastname: Malzone-Lott
authors.affiliation: MD. Physician, Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto (FMRP), Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil.
authors.forename: Mayra Fernanda
authors.initials: MF
authors.lastname: Sandoval Fagundes
authors.affiliation: MD. Attending Physician, Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto (FMRP), Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil.
authors.forename: Pedro Sérgio
authors.initials: PS
authors.lastname: Magnani
authors.affiliation: MD, MSc. Attending Physician, Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto (FMRP), Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil.
authors.forename: Mariana Alves
authors.initials: MA
authors.lastname: Fernandes Arouca
authors.affiliation: MD, PhD. Associate Professor, Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto (FMRP), Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil.
authors.forename: Omero Benedicto
authors.initials: OB
authors.lastname: Poli-Neto
authors.affiliation: MD, PhD. Associate Professor, Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto (FMRP), Universidade de São Paulo (USP), Ribeirão Preto (SP), Brazil.
authors.forename: Antônio Alberto
authors.initials: AA
authors.lastname: Nogueira
mesh_terms: D000328:Adult; D001938:Brazil; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D004522:Educational Status; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000150:complications / Q000175:diagnosis*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D063189:Symptom Assessment / Q000379:methods*; D014177:Translations; D014594:Uterine Neoplasms