title: Pulmonary Nocardia beijingensis infection associated with the use of alemtuzumab in a patient with multiple sclerosis.
abstract: Nocardia is a Gram-positive aerobic pathogen that usually affects immunocompromised patients. We report a case of pulmonary infection caused by a rare Nocardia species, Nocardia beijingensis, in a 50-year-old woman who had received alemtuzumab for the treatment of her multiple sclerosis. The invasive pulmonary infection was successfully treated with meropenem.
authors.affiliation: Department of Pharmacy Practice, Lebanese American University, Beirut, Lebanon.
authors.forename: Marwan
authors.initials: M
authors.lastname: Sheikh-Taha
authors.affiliation: Department of Internal Medicine, UAB School of Medicine, Huntsville, AL, USA.
authors.forename: Lourdes C
authors.initials: LC
authors.lastname: Corman
mesh_terms: D000074323:Alemtuzumab; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology*; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007155:Immunologic Factors / Q000009:adverse effects*; D000077731:Meropenem; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000188:drug therapy*; D009617:Nocardia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D018805:Sepsis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D013845:Thienamycins / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D061067:Antibodies, Monoclonal, Humanized; D007155:Immunologic Factors; D013845:Thienamycins; D000074323:Alemtuzumab; D000077731:Meropenem
keywords: Alemtuzumab; Nocardia beijingensis; multiple sclerosis; nocardiosis