title: Removal of a malignant cystic brain tumor utilizing pyoktanin blue and fibrin glue: Technical note.
abstract: BACKGROUND
  The leakage of cystic fluid during metastatic cystic brain tumor resection may cause tumor dissemination. When the cyst wall is thin, excision without removing the wall is often difficult.
  
  
  METHODS
  We were able to perform an en bloc resection of a cystic malignant brain tumor after aspirating the cystic fluid, injecting pyoktanin blue into the cyst to stain the cyst walls, and solidifying the empty cyst cavity by filling it with fibrin glue.
  
  
  RESULTS
  Pyoktanin blue readily stained the thin cystic walls and enabled visualization of mural damage. Solidification of the tumor made it easier to grasp and facilitated the dissection of tumor margins.
  
  
  CONCLUSIONS
  This method has the potential to become a useful technique for the resection of malignant cystic brain tumors.
authors.affiliation: Department of Neurosurgery, Wakayama Rosai Hospital, Wakayama, Wakayama, Japan.
authors.forename: Nobuhide
authors.initials: N
authors.lastname: Hayashi
authors.affiliation: Department of Neurosurgery, Wakayama Rosai Hospital, Wakayama, Wakayama, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Sasaki
authors.affiliation: Department of Neurosurgery, Wakayama Rosai Hospital, Wakayama, Wakayama, Japan.
authors.forename: Nagatsuki
authors.initials: N
authors.lastname: Tomura
authors.affiliation: Department of Neurosurgery, Wakayama Rosai Hospital, Wakayama, Wakayama, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Okada
authors.affiliation: Department of Neurosurgery, Wakayama Rosai Hospital, Wakayama, Wakayama, Japan.
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Kuwata
keywords: Cystic malignant brain tumor; fibrin glue; operative technique; pyoktanin blue