title: Orodispersible films: Towards drug delivery in special populations.
abstract: Orodispersible films (ODF) hold promise as a novel delivery method, with the potential to deliver tailored therapies to different patient populations. This article reviews the current strides of ODF technology and some of its unmet quality and manufacturing aspects. A topic highlights opportunities and limitations of inkjet printed ODF as a population-specific drug delivery. Overall, this article aims to stimulate further research to fill the current knowledge gap between manufacturing and administration requirements of ODF targeting specific patient subpopulations such as geriatrics.
authors.affiliation: School of Pharmacy, University College London (UCL), London, United Kingdom.
authors.forename: Mariagiovanna
authors.initials: M
authors.lastname: Scarpa
authors.affiliation: Graz University of Technology, Graz, Austria.
authors.forename: Sven
authors.initials: S
authors.lastname: Stegemann
authors.affiliation: Research Center Pharmaceutical Engineering GmbH, Graz, Austria.
authors.forename: Wen-Kai
authors.initials: WK
authors.lastname: Hsiao
authors.affiliation: Research Center Pharmaceutical Engineering GmbH, Graz, Austria.
authors.forename: Heinz
authors.initials: H
authors.lastname: Pichler
authors.affiliation: School of Pharmacy, University College London (UCL), London, United Kingdom.
authors.forename: Simon
authors.initials: S
authors.lastname: Gaisford
authors.affiliation: Research Center Pharmaceutical Engineering GmbH, Graz, Austria.
authors.forename: Massimo
authors.initials: M
authors.lastname: Bresciani
authors.affiliation: Graz University of Technology, Graz, Austria; Research Center Pharmaceutical Engineering GmbH, Graz, Austria. Electronic address: amrit.paudel@rcpe.at.
authors.forename: Amrit
authors.initials: A
authors.lastname: Paudel
authors.affiliation: School of Pharmacy, University College London (UCL), London, United Kingdom.
authors.forename: Mine
authors.initials: M
authors.lastname: Orlu
mesh_terms: D000284:Administration, Oral; D002626:Chemistry, Pharmaceutical; D016503:Drug Delivery Systems; D006801:Humans; D007281:Ink; D011108:Polymers; D011327:Printing
chemical_list: D011108:Polymers
keywords: Acceptability; Disintegration; Drop-on-demand; Inkjet printing; Orodispersible film; Substrate