title: Effect of Switching between Pressure-controlled and Volume-controlled Ventilation on Respiratory Mechanics and Hemodynamics in Obese Patients during Abdominoplasty.
abstract: BACKGROUND
  The ideal intraoperative ventilation strategy in obese patients remains obscure. This prospective, randomized study was designed to evaluate the effect of pressure-controlled ventilation (PCV) before or after volume-controlled ventilation (VCV) on lung mechanics and hemodynamics variables in obese patients subjected to abdominoplasty operation.
  
  
  METHODS
  The study included forty patients with body mass index 30-45 kg/m2subjected to abdominoplasty. All patients were randomly allocated in two groups after the induction of general anesthesia (twenty patients each), according to intraoperative ventilatory strategy. Group I (P-V): started with PCV until the plication of rectus muscle changes into VCV till the end of surgery. Group II (V-P): started with VCV until the plication of rectus muscle changes into PCV till the end of surgery. Lung mechanics, hemodynamics variables (heart rate and mean blood pressure), and arterial blood gases (ABGs) were recorded.
  
  
  RESULTS
  No significant difference in the hemodynamics and ABGs were recorded between the studied groups. The use of PCV after VCV induced the improvement of lung mechanics.
  
  
  CONCLUSIONS
  Switching from VCV to PCV is preferred to improve intraoperative oxygenation and lung compliance without adverse hemodynamic effects in obese patients.
authors.affiliation: Department of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, Mansoura University Hospital, Mansoura, Egypt.
authors.forename: Medhat Mikhail
authors.initials: MM
authors.lastname: Messeha
keywords: Hemodynamics; obesity; pressure-controlled ventilation; respiratory mechanics; volume-controlled ventilation