title: Acute hepatitis E virus infection causing acute liver failure requiring living-donor liver transplantation in a non-pregnant immunocompetent woman.
abstract: We report a rare case of acute liver failure from acute hepatitis E virus (HEV) in a non-pregnant woman without comorbidities who survived after liver transplantation. The source was likely consumption of partially cooked pig liver. HEV genotype 3 is the second most common genotype causing acute hepatitis E in developed countries. Fulminant hepatitis E rarely occurs without a risk factor, as in our patient. Vigilant monitoring for chronic hepatitis E in post-transplant immunocompromised patients is needed.
authors.affiliation: Queen Mary Hospital, Hong Kong, China.|School of Public Health, The University of Hong Kong, Hong Kong, China.
authors.forename: Iris Wai Sum
authors.initials: IWS
authors.lastname: Li
authors.affiliation: Department of Surgery, The University of Hong Kong, Hong Kong, China.
authors.forename: Kenneth Siu Ho
authors.initials: KSH
authors.lastname: Chok
mesh_terms: D000208:Acute Disease; D000818:Animals; D005260:Female; D005838:Genotype; D006501:Hepatic Encephalopathy / Q000097:blood / Q000601:surgery* / Q000821:virology; D016751:Hepatitis E / Q000097:blood / Q000150:complications / Q000601:surgery* / Q000821:virology; D016752:Hepatitis E virus / Q000235:genetics / Q000302:isolation & purification*; D006723:Hong Kong; D006801:Humans; D017114:Liver Failure, Acute / Q000097:blood / Q000601:surgery* / Q000821:virology; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008460:Meat / Q000821:virology*; D008875:Middle Aged; D012307:Risk Factors; D013552:Swine; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
keywords: acute liver failure; fulminant hepatitis; hepatitis E; liver transplant