title: Skin Erythema, Pigmentation and Hydration Kinetics after Ultraviolet Radiation-induced Photodamage in Southern Chinese Women.
abstract: Although there have been some studies about changes of skin erythema and pigmentation following ultraviolet radiation in other races, the relevant data in Chinese have never been achieved. Thus, we evaluated the long-time course of skin erythema, pigmentation and hydration changes after different doses of solar-simulated ultraviolet (SSUV) irradiation in 26 Chinese women for 168 days. The erythema index increased abruptly and peaked during 3 days of SSUV exposure, then slowly returned to the baseline level starting at day 7 and completely recovered during 168-day course of this study only in one minimal erythema doses (MED) SSUV irradiation. The melanin index started to slowly increase at day 3 of SSUV exposure, peaking at day 14 and gradually returned to the baseline level thereafter, but did not return to the baseline level during 168-day course in all doses. Skin hydration slowly declined at day 3 of exposure, hitting the lowest point at day 7, then slowly recovered starting at day 14 and completely returned to the baseline level at day 28 only in 1.5MED. These results will serve as baseline data on Chinese skin and provide useful references for the treatment of serious skin photodamage in Chinese.
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Miaojian
authors.initials: M
authors.lastname: Wan
authors.affiliation: Skin Research Center, Landproof Testing Technology Co., Ltd, Guangzhou, Guangdong Province, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Hu
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Xie
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Zijian
authors.initials: Z
authors.lastname: Gong
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Jinling
authors.initials: J
authors.lastname: Yi
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Xie
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Guan
authors.affiliation: Skin Research Center, Landproof Testing Technology Co., Ltd, Guangzhou, Guangdong Province, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Guan
authors.affiliation: Department of Dermatology & Venerology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Lai
mesh_terms: D000328:Adult; D044466:Asian People; D002681:China; D004307:Dose-Response Relationship, Radiation; D004890:Erythema / Q000208:ethnology / Q000209:etiology*; D005260:Female; D006801:Humans; D007700:Kinetics; D008543:Melanins / Q000378:metabolism; D012867:Skin / Q000378:metabolism* / Q000528:radiation effects*; D012880:Skin Pigmentation / Q000528:radiation effects*; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014867:Water; D055815:Young Adult
chemical_list: D008543:Melanins; D014867:Water