title: Tailoring strategies for the management of depression in midlife years.
abstract: Depression affects one in every five adults in North America. Women are more affected than men, possibly because of genetics, coping strategies, and hormone variations. The concept of a menopause-associated depression, however, remains a complex and controversial topic. Although hormone therapy is not recommended as first-line therapy for depression in midlife women, estrogen-based hormone therapy may minimize the need for or enhance the response to antidepressant or behavior-based therapies in select perimenopausal women.
authors.affiliation: Queen's University School of Medicine, Kingston, Ontario, Canada.
authors.forename: Claudio N
authors.initials: CN
authors.lastname: Soares
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D001521:Behavior Therapy; D003863:Depression / Q000517:prevention & control / Q000628:therapy*; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008593:Menopause / Q000502:physiology*; D008875:Middle Aged; D012307:Risk Factors; D016387:Women's Health
chemical_list: D000928:Antidepressive Agents