title: [Influence of the Potassium Channels Activator Nicorandil to the Quality of Life in Patients With Ishemic Heart Disease and Stable Angina Pectoris].
abstract: The aim of the study to assess the influence of medicamentous therapy to the quality of life of ischemic heart disease patients with stable angina pectoris by activator potassium channels nicorandil in comparison with traditional therapy by isosorbide dinitrate. The study included 84 ischemic heart disease patients. Authors consider quality of life as an estimated category of state of the subject in an illness situation. The dynamic of physical and psychological components of quality of life are compared in ischemic heart disease patients under the treatment by nicorandil and isosorbide dinitrate. Indicators of quality of life, defined on the basis of a questionnaires of SAQ and GHQ supplementing an illness picture, are an multiple-factor criterion of an assessment of a condition of this category of patients. The benefits of nicorandil in influence on quality of life indicators were revealed in the study.
authors.affiliation: Sechenov First Moscow State Medical University, Moscow, Russia.|Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia.
authors.forename: Zh M
authors.initials: ZM
authors.lastname: Sizova
authors.affiliation: Sechenov First Moscow State Medical University, Moscow, Russia.|Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia.
authors.forename: V L
authors.initials: VL
authors.lastname: Zakharova
authors.affiliation: Sechenov First Moscow State Medical University, Moscow, Russia.|Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Kozlova
authors.affiliation: Sechenov First Moscow State Medical University, Moscow, Russia.|Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia.
authors.forename: T S
authors.initials: TS
authors.lastname: Kuchkina
mesh_terms: D000368:Aged; D060050:Angina, Stable / Q000188:drug therapy* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020108:Nicorandil / Q000494:pharmacology* / Q000627:therapeutic use; D015221:Potassium Channels / Q000819:agonists*; D011788:Quality of Life; D014665:Vasodilator Agents / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D015221:Potassium Channels; D014665:Vasodilator Agents; D020108:Nicorandil
keywords: angina pectoris; ischemic heart disease; nicorandil; pharmacotherapy; quality of life