title: Lucio's phenomenon: exuberant case report and review of Brazilian cases.
abstract: Lucio's phenomenon is an uncommon reaction characterized by severe necrotizing cutaneous lesions that occurs in patients with Lucio's leprosy and lepromatous leprosy. It is considered by some authors as a variant of type 2 or 3 reaction. Death can occur because of blood dyscrasia or sepsis. Precipitating factors include infections, drugs and pregnancy. We report a 31-year-old female patient exhibiting both clinical and histopathological features of lepromatous leprosy and Lucio's phenomenon presenting favorable response to treatment. We complement our report with a literature review of the Brazilian cases of Lucio's phenomenon published in Portuguese and English.
authors.affiliation: Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
authors.forename: Rafael Henrique
authors.initials: RH
authors.lastname: Rocha
authors.affiliation: Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
authors.forename: Paulo Sergio
authors.initials: PS
authors.lastname: Emerich
authors.affiliation: Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
authors.forename: Lucia Martins
authors.initials: LM
authors.lastname: Diniz
authors.affiliation: Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
authors.forename: Marcela Bahia Barretto de
authors.initials: MB
authors.lastname: Oliveira
authors.affiliation: Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
authors.forename: Aline Neves Freitas
authors.initials: AN
authors.lastname: Cabral
authors.affiliation: Universidade Federal do Espírito Santo (UFES) - Vitória (ES), Brazil.
authors.forename: Ana Cristina Vervloet do
authors.initials: AC
authors.lastname: Amaral
mesh_terms: D000328:Adult; D001706:Biopsy; D001938:Brazil; D005260:Female; D006801:Humans; D015440:Leprosy, Lepromatous / Q000188:drug therapy / Q000473:pathology*; D009336:Necrosis; D012720:Severity of Illness Index; D012867:Skin / Q000473:pathology; D012883:Skin Ulcer / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome