title: Effects of cytochalasin H on developing frog embryos: reversibility of action.
abstract: Cytochalasin H (CH) brought about cellular disaggregation resulting into arrest of development in the embryos of the frog, Microhyla ornata. The effects were dependent on the dose of CH, duration of the treatment as well as on developmental stage of the embryo at the beginning of the treatment. The embryos were protected to some extent if the vitelline membranes were left intact. The reversibility of CH-action, after transfer of treated embryos to CH-free medium, was dependent on the extent of cellular disaggregation brought about by CH and on the presence or absence of an intact vitelline membrane.
authors.affiliation: Department of Zoology, University of Poona, 411 007, Pune.
authors.forename: Gauri
authors.initials: G
authors.lastname: Wadekar
authors.affiliation: Department of Zoology, M.A.C.S. Research Institute, 411 004, Pune, India.
authors.forename: Surendra
authors.initials: S
authors.lastname: Ghaskadbi
authors.affiliation: Department of Zoology, University of Poona, 411 007, Pune.
authors.forename: Leela
authors.initials: L
authors.lastname: Mulherkar
keywords: Abnormal development; Cellular disaggregation; Cytochalasin H; Frog embryos; Reversibility of CH action