title: Prevalence and Factors Associated with Hazardous Alcohol Use Among Persons Living with HIV Across the US in the Current Era of Antiretroviral Treatment.
abstract: Hazardous alcohol use is associated with detrimental health outcomes among persons living with HIV (PLWH). We examined the prevalence and factors associated with hazardous alcohol use in the current era using several hazardous drinking definitions and binge drinking defined as ≥5 drinks for men versus ≥4 for women. We included 8567 PLWH from 7 U.S. sites from 2013 to 2015. Current hazardous alcohol use was reported by 27% and 34% reported binge drinking. In adjusted analyses, current and past cocaine/crack (odd ratio [OR] 4.1:3.3-5.1, p < 0.001 and OR 1.3:1.1-1.5, p < 0.001 respectively), marijuana (OR 2.5:2.2-2.9, p < 0.001 and OR 1.4:1.2-1.6, p < 0.001), and cigarette use (OR 1.4:1.2-1.6, p < 0.001 and OR 1.3:1.2-1.5, p < 0.001) were associated with increased hazardous alcohol use. The prevalence of hazardous alcohol use remains high in the current era, particularly among younger men. Routine screening and targeted interventions for hazardous alcohol use, potentially bundled with interventions for other drugs, remain a key aspect of HIV care.
authors.affiliation: Department of Medicine, University of Washington, 325 9th Ave Box 359931, Seattle, WA, USA. hcrane@uw.edu.
authors.forename: Heidi M
authors.initials: HM
authors.lastname: Crane
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Mary E
authors.initials: ME
authors.lastname: McCaul
authors.affiliation: Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Geetanjali
authors.initials: G
authors.lastname: Chander
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Heidi
authors.initials: H
authors.lastname: Hutton
authors.affiliation: Department of Medicine, University of Washington, 325 9th Ave Box 359931, Seattle, WA, USA.
authors.forename: Robin M
authors.initials: RM
authors.lastname: Nance
authors.affiliation: Department of Epidemiology, University of Washington, Seattle, WA, USA.
authors.forename: Joseph A C
authors.initials: JAC
authors.lastname: Delaney
authors.affiliation: Department of Medicine, University of Washington, 325 9th Ave Box 359931, Seattle, WA, USA.
authors.forename: Joseph O
authors.initials: JO
authors.lastname: Merrill
authors.affiliation: Department of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Bryan
authors.initials: B
authors.lastname: Lau
authors.affiliation: Fenway Institute and Department of Medicine, Harvard Medical School, Boston, MA, USA.
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Mayer
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Mugavero
authors.affiliation: Fenway Institute and Division of Psychiatry, Harvard Medical School, Boston, MA, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Mimiaga
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: James H
authors.initials: JH
authors.lastname: Willig
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Greer A
authors.initials: GA
authors.lastname: Burkholder
authors.affiliation: Department of Medicine, University of Washington, 325 9th Ave Box 359931, Seattle, WA, USA.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Drozd
authors.affiliation: Department of Medicine, University of Washington, 325 9th Ave Box 359931, Seattle, WA, USA.
authors.forename: Rob J
authors.initials: RJ
authors.lastname: Fredericksen
authors.affiliation: Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Karen
authors.initials: K
authors.lastname: Cropsey
authors.affiliation: Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Richard D
authors.initials: RD
authors.lastname: Moore
authors.affiliation: Department of Psychology, University of Washington, Seattle, WA, USA.
authors.forename: Jane M
authors.initials: JM
authors.lastname: Simoni
authors.affiliation: Department of Medicine, University of California at San Diego, San Diego, CA, USA.
authors.forename: W
authors.initials: W
authors.lastname: Christopher Mathews
authors.affiliation: Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Eron
authors.affiliation: Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.
authors.forename: Sonia
authors.initials: S
authors.lastname: Napravnik
authors.affiliation: Department of Medicine, University of California at San Francisco, San Francisco, CA, USA.
authors.forename: Katerina
authors.initials: K
authors.lastname: Christopoulos
authors.affiliation: Department of Medicine, University of California at San Francisco, San Francisco, CA, USA.
authors.forename: Elvin
authors.initials: E
authors.lastname: Geng
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Saag
authors.affiliation: Department of Medicine, University of Washington, 325 9th Ave Box 359931, Seattle, WA, USA.
authors.forename: Mari M
authors.initials: MM
authors.lastname: Kitahata
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000453:epidemiology*; D000437:Alcoholism / Q000453:epidemiology*; D019380:Anti-HIV Agents / Q000627:therapeutic use; D063425:Binge Drinking / Q000453:epidemiology*; D000073865:Cigarette Smoking / Q000453:epidemiology; D019970:Cocaine-Related Disorders / Q000453:epidemiology; D016578:Crack Cocaine; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008297:Male; D000074609:Marijuana Use / Q000453:epidemiology; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D014481:United States / Q000453:epidemiology
chemical_list: D019380:Anti-HIV Agents; D016578:Crack Cocaine
keywords: Alcohol use; HIV; Hepatitis C; Substance use