title: Antimicrobial Properties of Copper Nanoparticles and Amino Acid Chelated Copper Nanoparticles Produced by Using a Soya Extract.
abstract: This paper reports a comparison of the antibacterial properties of copper-amino acids chelates and copper nanoparticles againstEscherichia coli,Staphylococcus aureus, andEnterococcus faecalis. These copper-amino acids chelates were synthesized by using a soybean aqueous extract and copper nanoparticles were produced using as a starting material the copper-amino acids chelates species. The antibacterial activity of the samples was evaluated by using the standard microdilution method (CLSI M100-S25 January 2015). In the antibacterial activity assays copper ions and copper-EDTA chelates were included as references, so that copper-amino acids chelates can be particularly suitable for acting as an antibacterial agent, so they are excellent candidates for specific applications. Additionally, to confirm the antimicrobial mechanism on bacterial cells, MTT assay (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) was carried out. A significant enhanced antimicrobial activity and a specific strain were found for copper chelates overE. faecalis. Its results would eventually lead to better utilization of copper-amino acids chelate for specific application where copper nanoparticles can be not used.
authors.affiliation: Doctorado Institucional en Ingeniería y Ciencia de Materiales, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico; Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: I
authors.initials: I
authors.lastname: DeAlba-Montero
authors.affiliation: Facultad de Estomatología, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: Jesús
authors.identifier: 0000-0002-4452-0046
authors.initials: J
authors.lastname: Guajardo-Pacheco
authors.affiliation: Departamento Físico Matemático, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: Elpidio
authors.initials: E
authors.lastname: Morales-Sánchez
authors.affiliation: Coordinación para la Innovación y Aplicación de la Ciencia y Tecnología, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: Rene
authors.initials: R
authors.lastname: Araujo-Martínez
authors.affiliation: Coordinación para la Innovación y Aplicación de la Ciencia y Tecnología, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: G M
authors.identifier: 0000-0003-4681-749X
authors.initials: GM
authors.lastname: Loredo-Becerra
authors.affiliation: Facultad de Estomatología, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: Gabriel-Alejandro
authors.identifier: 0000-0003-4982-5225
authors.initials: GA
authors.lastname: Martínez-Castañón
authors.affiliation: Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: Facundo
authors.identifier: 0000-0001-6589-5958
authors.initials: F
authors.lastname: Ruiz
authors.affiliation: Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí, SLP, Mexico.
authors.forename: M E
authors.identifier: 0000-0001-9073-3600
authors.initials: ME
authors.lastname: Compeán Jasso