title: Two new compounds from the green peel of Juglans mandshurica.
abstract: A new cyclic diarylheptanoid (1) and a new flavone glucoside (2), along with seven known compounds, were isolated from the green peel of Juglans mandshurica. Their structures were elucidated based on extensive spectroscopic analyses. Moreover, the cytotoxicity against NCI-H460, A549, and K562 cancer cells of compounds 1-6 was evaluated. The results showed that compound 3 exhibited moderate inhibitory potency against the growth of three cell lines.
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.
authors.forename: Kang-Ping
authors.initials: KP
authors.lastname: Xu
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.
authors.forename: Zhen-Xing
authors.initials: ZX
authors.lastname: Zou
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zou
authors.affiliation: c The First Hospital of Hunan University of Chinese Medicine , Changsha 410007 , China.
authors.forename: Hong-Ping
authors.initials: HP
authors.lastname: Long
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.
authors.forename: Lei-Hong
authors.initials: LH
authors.lastname: Tan
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.
authors.forename: Rui-Huan
authors.initials: RH
authors.lastname: Liu
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.
authors.forename: Yi-Kun
authors.initials: YK
authors.lastname: Wang
authors.affiliation: b Xiangya Hospital of Central South University , Changsha 410008 , China.
authors.forename: Ping-Sheng
authors.initials: PS
authors.lastname: Xu
authors.affiliation: a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha 410013 , China.|b Xiangya Hospital of Central South University , Changsha 410008 , China.
authors.forename: Gui-Shan
authors.initials: GS
authors.lastname: Tan
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D036381:Diarylheptanoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D031324:Juglans / Q000737:chemistry*; D020014:K562 Cells; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D036381:Diarylheptanoids; D004365:Drugs, Chinese Herbal; D047309:Flavones; D005960:Glucosides; D010936:Plant Extracts; C000625073:juglanin D; C000625074:rhamnetin-3-O-beta-D-xylopyranoside
keywords: Juglans mandshurica; cytotoxicity; diarylheptanoid; flavone glycoside