title: Expression of leptin receptor in the oviduct of Chinese brown frog (Rana dybowskii).
abstract: The oviduct of Chinese brown frog (Rana dybowskii) expands specifically during prehibernation instead of in the breeding period. In this study, we investigated the expression of leptin receptor (Ob-Rb) inRana dybowskiioviduct during the breeding period and prehibernation. Histologically, the oviduct ofRana dybowskiiconsists of glandular cells, tubule lumen, and epithelial cells. The oviductal weight and pipe diameter also revealed significant differences, which were higher in prehibernation than that of the breeding period. Ob-Rb was observed in stromal cells of oviductal tissue in both the breeding period and prehibernation. The mean protein and mRNA levels of the Ob-Rb were significantly higher in prehibernation as compared with the breeding period. In addition, oviductal content of leptin was also higher in prehibernation than that of the breeding period. These results suggested that oviduct ofRana dybowskiimight be a target organ of leptin, and leptin may play an autocrine/paracrine role mediated by Ob-Rb in regulating the oviductal hypertrophy during prehibernation.
authors.affiliation: College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China; and.
authors.forename: Liqin
authors.initials: L
authors.lastname: Xi
authors.affiliation: College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China; and.
authors.forename: Yuning
authors.initials: Y
authors.lastname: Liu
authors.affiliation: College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China; and.
authors.forename: Zeqi
authors.initials: Z
authors.lastname: Tang
authors.affiliation: Department of Biosciences, University of Oslo, Oslo, Norway.
authors.forename: Xia
authors.initials: X
authors.lastname: Sheng
authors.affiliation: College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China; and.
authors.forename: Haolin
authors.initials: H
authors.lastname: Zhang
authors.affiliation: College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China; and.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Weng
authors.affiliation: College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China; and xumeiyu@bjfu.edu.cn.
authors.forename: Meiyu
authors.initials: M
authors.lastname: Xu
mesh_terms: D029845:Amphibian Proteins / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D001947:Breeding; D005260:Female; D005786:Gene Expression Regulation; D006605:Hibernation; D009929:Organ Size; D010057:Oviducts / Q000033:anatomy & histology / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D011898:Ranidae / Q000033:anatomy & histology / Q000235:genetics / Q000378:metabolism*; D054411:Receptors, Leptin / Q000235:genetics / Q000378:metabolism*; D012098:Reproduction
chemical_list: D029845:Amphibian Proteins; D012333:RNA, Messenger; D054411:Receptors, Leptin
keywords: Rana dybowskii; leptin; leptin receptor; oviduct; regulation