title: Effect on Microbial Growth of a New Skin Protectant Formulation.
abstract: Objective:Evaluate the effect of a new investigational skin protectant formulation on the growth of various microorganismsin vitro.Approach:Anin vitrolaboratory assay with various species of gram-positive bacteria, gram-negative bacteria, and yeast grown on agar plates was used to verify that a new investigational product used for the management of incontinence-associated dermatitis (IAD) does not support microbial growth.Results:The investigational product did not support the growth of all organisms tested for 48 h in these assays. The results demonstrate the barrier properties of this investigational formulation against bacteria and yeast that are relevant to incontinent patients.Innovation:IAD accompanied by skin damage is difficult to manage with currently available products. A new skin protectant that can be applied as a liquid and polymerizes into a breathable filmin situeven in the presence of exudate (as shown previously) has been developed and tested to ensure that it does not support microbial growth.Conclusion:This work verifies that this new product does not support microbial growthin vitrousing organisms relevant for the intended application.
authors.affiliation: 3M Critical & Chronic Care Solutions Division , St. Paul, Minnesota.
authors.forename: Joseph
authors.initials: J
authors.lastname: Stoffel
authors.affiliation: 3M Health Care Clinical Operations , St. Paul, Minnesota.
authors.forename: Stéphanie F
authors.initials: SF
authors.lastname: Bernatchez
keywords: in vitro; incontinence-associated dermatitis; microbial growth; skin protectant