title: Potential prevention by oral DHEA of superficial tears in elderly atrophic skin.
abstract: Oral DHEA improves skin hydration and sebum production as well as bone mineral density in older patients while limiting progression of their skin atrophy. Topical DHEA cream stimulates local collagen production. Trials of oral DHEA should be undertaken to examin their potential for preventing tears in fragile aging skin.
authors.affiliation: Department of Family Practice, University of California Medical School at Davis, Davis, CA, USA. Electronic address: hwdaniell@aol.com.
authors.forename: Harry W
authors.initials: HW
authors.lastname: Daniell
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D001284:Atrophy; D002986:Clinical Trials as Topic; D003681:Dehydration / Q000178:diet therapy* / Q000503:physiopathology; D003687:Dehydroepiandrosterone / Q000009:adverse effects / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D019587:Dietary Supplements / Q000009:adverse effects; D006801:Humans; D008875:Middle Aged; D012629:Sebum / Q000378:metabolism; D012867:Skin / Q000293:injuries* / Q000378:metabolism / Q000473:pathology; D014947:Wounds and Injuries / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*
chemical_list: D003879:Dermatologic Agents; D003687:Dehydroepiandrosterone
keywords: DHEA; Prevention; Skin Tears