title: [Chemotherapy-induced peripheral neuropathy and neuropathic pain].
abstract: The perception of the media is that chemotherapy is mainly associated with nausea, vomiting and hair loss. In the longer term the development of peripheral neuropathy, i.e. chemotherapy-induced peripheral neuropathy (CIPN) is often more important for patients. The CIPN represents a side effect of many antineoplastic substances with severe functional impairment and its prevention and treatment is an important task. In addition to many interventions, which have been shown to be ineffective, physiotherapeutic measures and possibly the prophylactic application of cold are helpful for prevention. Randomized studies on the treatment of painful CIPN provided positive data for duloxetine and to a lesser extent for venlafaxine.
authors.affiliation: PalliativCentrum, Universitätsklinikum Carl Gustav Carus, Fetscherstr. 74, 01307, Dresden, Deutschland. ulrich.schuler@tu-dresden.de.
authors.forename: U
authors.initials: U
authors.lastname: Schuler
authors.affiliation: PalliativCentrum, Universitätsklinikum Carl Gustav Carus, Fetscherstr. 74, 01307, Dresden, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Heller
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D017679:Cryotherapy; D000068736:Duloxetine Hydrochloride / Q000627:therapeutic use; D006801:Humans; D009437:Neuralgia / Q000139:chemically induced* / Q000517:prevention & control / Q000628:therapy; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000517:prevention & control / Q000628:therapy; D026741:Physical Therapy Modalities; D016032:Randomized Controlled Trials as Topic; D000069470:Venlafaxine Hydrochloride / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D000069470:Venlafaxine Hydrochloride; D000068736:Duloxetine Hydrochloride
keywords: Duloxetine; Peripheral nervous system diseases, prevention & control; Physical therapy modalities; Platinum compounds; Vinca alkaloids