title: Understanding the role of serotonin in psychiatric diseases.
abstract: Serotonin (5-HT) continues to attract researchers' interest after almost a century. However, despite these efforts, its role has not yet been fully elucidated. It is now evident that 5-HT does not modulate single functions but rather a multiplicity of activities and behaviors present in both normal and several pathological conditions in a less deterministic way than previously assumed. This article aims to briefly review some of the latest advancements in the general role of 5-HT in psychiatry, particularly in depression, and offer the author's personal reflections.
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, Via Roma, 67, 56100 Pisa, Italy.
authors.forename: Donatella
authors.initials: D
authors.lastname: Marazziti
keywords: depression; pathophysiology; psychiatric disorders; serotonin