title: A comprehensive review of an unmet public health issue: resistant hypertension.
abstract: Resistant hypertension is an intractable problem to patients and physicians. In recent decades, a substantial amount of basic and epidemiological studies provide us a vast number of valuable evidence and information about this once elusive disease. Better understanding about this entity could help physicians improve diagnostic and therapeutic accuracy. In present review, therefore, we first will detail the definition and diagnosis of resistant hypertension between cardiology societies, and followed by the information of prevalence of resistant hypertension around the world, and then briefly discuss currently used different nomenclature of resistant hypertension, and finally present diagnostic and therapeutic strategies of resistant hypertension.
authors.affiliation: a Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.|b Jinwan Hospital of Zhuhai, Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.
authors.forename: Anping
authors.initials: A
authors.lastname: Cai
authors.affiliation: a Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.
authors.forename: Yingqing
authors.initials: Y
authors.lastname: Feng
authors.affiliation: a Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.|b Jinwan Hospital of Zhuhai, Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China.
authors.forename: Yingling
authors.initials: Y
authors.lastname: Zhou
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D006301:Health Services Needs and Demand; D006801:Humans; D006973:Hypertension / Q000145:classification / Q000188:drug therapy / Q000453:epidemiology*; D015995:Prevalence; D011634:Public Health
chemical_list: D000959:Antihypertensive Agents
keywords: Epidemiology; pharmacology; resistant hypertension