title: Lower-Extremity Pseudomyogenic Hemangioendothelioma on Bone Scintigraphy and PET/CT.
abstract: An otherwise healthy 33-year-old man presents with new pain involving the right leg. Radiographs of the femur showed scattered lucent lesions. An MRI of the knee demonstrated nonspecific cortical-based lesions. Biopsy confirmed pseudomyogenic hemangioendothelioma. MDP bone scan and F-FDG PET/CT were obtained to evaluate for extent of disease demonstrating disease limited to the bone of the right leg. Interestingly, the FDG and MDP uptake and CT appearance of the disease were not entirely concordant, with some lesions being lytic on CT and associated with FDG and MDP uptake, other lesions being CT silent and either MDP or FDG avid.
authors.affiliation: From the *Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY; †IRCCS SDN, Naples, Italy; ‡Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY; §Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT; and ∥Carson GrahamSecondary School, North Vancouver, British Columbia, Canada.
authors.forename: Simone
authors.initials: S
authors.lastname: Krebs
authors.forename: Serena
authors.initials: S
authors.lastname: Monti
authors.forename: Natasha
authors.initials: N
authors.lastname: Lewis
authors.forename: Alessandro
authors.initials: A
authors.lastname: Luciano
authors.forename: Lapo
authors.initials: L
authors.lastname: Rastrelli
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Mannelli
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D005269:Femur / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006390:Hemangioendothelioma / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D013669:Technetium Tc 99m Medronate