title: Effect of FiO2in the measurement of VO2and VCO2using the E-COXV metabolic monitor.
abstract: OBJECTIVE
  We evaluated the effect of changes in FiO2on the bias and accuracy of the determination of oxygen consumption (V˙O2) and carbon dioxide production (V˙CO2) using the E-COVX monitor in patients with mechanical ventilation.
  
  
  METHODS
  Descriptive of concordance.
  
  
  METHODS
  Intensive Care Unit.
  
  
  METHODS
  Patients with mechanical ventilation.
  
  
  METHODS
  We measured V˙O2and V˙CO2using the E-COVX monitor. Values recorded were the average in 5min. Two groups of 30 patients. We analyzed: 1) the reproducibility in the measurement of V˙O2and V˙CO2at FiO20.4, and 2) the effect of the changes in FiO2on the measurement of V˙O2and V˙CO2. Statistical analysis was performed using Bland and Altman test.
  Bias and accuracy.
  
  
  RESULTS
  1) FiO20.4 reproducibility: The bias in the measurement of V˙O2and V˙CO2was 1.6 and 2.1mL/min, respectively, and accuracy was 9.7 to -8.3% and 7.2 to -5.2%, respectively, and 2) effect of FiO2on V˙O2: The bias of V˙O2measured at FiO20.4 and 0.6 was -4.0mL/min and FiO20.4 and 0.8 was 5.2mL/min. Accuracy between FiO20.4 and 0.6 was 11.9 to -14.1%, and between FiO20.4 and 0.8 was 43.9 to -39.7%.
  
  
  CONCLUSIONS
  The E-COVX monitor evaluates V˙O2and V˙CO2in critical patients with mechanical ventilation with a clinically acceptable accuracy until FiO20.6.
authors.affiliation: Servei de Medicina Intensiva, Hospital Universitari Son Espases, Palma de Mallorca, España.
authors.forename: M
authors.initials: M
authors.lastname: Ferreruela
authors.affiliation: Servei de Medicina Intensiva, Hospital Universitari Son Espases, Palma de Mallorca, España. Electronic address: joan.raurich@ssib.es.
authors.forename: J M
authors.initials: JM
authors.lastname: Raurich
authors.affiliation: Servei de Medicina Intensiva, Hospital Universitari Son Espases, Palma de Mallorca, España.
authors.forename: J A
authors.initials: JA
authors.lastname: Llompart-Pou
authors.affiliation: Servei de Medicina Intensiva, Hospital Universitari Son Espases, Palma de Mallorca, España.
authors.forename: A
authors.initials: A
authors.lastname: Colomar
authors.affiliation: Servei de Medicina Intensiva, Hospital Universitari Son Espases, Palma de Mallorca, España.
authors.forename: I
authors.initials: I
authors.lastname: Ayestarán
mesh_terms: D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000494:pharmacology; D001944:Breath Tests / Q000295:instrumentation*; D002153:Calorimetry, Indirect; D002245:Carbon Dioxide / Q000378:metabolism*; D003422:Critical Care; D002149:Energy Intake; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D008176:Lung Volume Measurements / Q000295:instrumentation; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D010100:Oxygen / Q000032:analysis; D010101:Oxygen Consumption; D011659:Pulmonary Gas Exchange; D015203:Reproducibility of Results; D012121:Respiration, Artificial
chemical_list: D000701:Analgesics, Opioid; D006993:Hypnotics and Sedatives; D002245:Carbon Dioxide; D010100:Oxygen
keywords: Carbon dioxide; Consumo de oxígeno; Critical illness; Dióxido de carbono; Intercambio pulmonar de gases; Mechanical ventilation; Oxygen consumption; Paciente crítico; Pulmonary gas exchange; Reproducibilidad de resultados; Reproducibility of results; Ventilación mecánica