title: Polyribosome formation and poly(A)-containing RNA in embryos of the sand dollar,Dendraster excentricus.
abstract: The pattern of appearance of ribosomes, newly synthesized mRNA, and poly(A)-containing mRNA in polyribosomes has been examined in sand dollar embryos. From early blastula until shortly before hatching small polyribosomes engaged in histone synthesis predominate. At the time of hatching, when the rate of cell increase is maximal, the proportion of poly(A)-containing RNA in polyribosomes is low. After hatching a new class of large polyribosomes appears and the amount of poly(A)-containing polyribosomal RNA increases. Cordycepin, an inhibitor of RNA adenylylation, prevents the appearance of the large polyribosomes after hatching as well as the increase in poly(A)-containing polyribosomal RNA.
authors.affiliation: Department of Zoology, University of Washington, 98195, Seattle, Washington, USA.|the Friday Harbor Laboratories, University of Washington, 98195, Seattle, Washington, USA.
authors.forename: John
authors.initials: J
authors.lastname: Spieth
authors.affiliation: Department of Zoology, University of Washington, 98195, Seattle, Washington, USA.|the Friday Harbor Laboratories, University of Washington, 98195, Seattle, Washington, USA.
authors.forename: Arthur H
authors.initials: AH
authors.lastname: Whiteley
keywords: Cordycepin; Echinoids; Poly(A); Polyribosomes