title: [Surgery for pediatric intractable epilepsy due to posterior quadrantic cortical dysplasia].
abstract: OBJECTIVE
  To investigate the clinical features and surgical strategy for pediatric intractable epilepsy due to posterior quadrantic cortical dysplasia and to assess the surgical outcomes.
  
  
  METHODS
  The clinical features and preoperative evaluation results of 14 children with intractable epilepsy due to posterior quadrantic cortical dysplasia were retrospectively analyzed. The localization values of video-electroencephalography and intraoperative monitoring and the indications, advantages and disadvantages of temporoparietooccipital disconnection were evaluated.
  
  
  RESULTS
  The 14 children had different seizure types, of which spasm was the most common one. The lesions of cortical dysplasia involved the central cerebral region in 2 cases. After temporoparietooccipital disconnection in 14 patients, 13 cases were seizure-free; only one case still had seizures, but the frequency dropped by more than 50%.
  
  
  CONCLUSIONS
  Temporoparietooccipital disconnection is a safe and effective surgical procedure for children with intractable epilepsy due to posterior quadrantic cortical dysplasia.
authors.affiliation: Pediatric Epilepsy Center, Peking University First Hospital, Beijing 100034, China. cailx1010@bjmu.edu.com.
authors.forename: Qing-Zhu
authors.initials: QZ
authors.lastname: Liu
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Cai
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Liu
authors.forename: Yu-Wu
authors.initials: YW
authors.lastname: Jiang
authors.forename: Shuang
authors.initials: S
authors.lastname: Wang
authors.forename: Tao-Yun
authors.initials: TY
authors.lastname: Ji
authors.forename: Wen
authors.initials: W
authors.lastname: Wang
authors.forename: Wei-Ke
authors.initials: WK
authors.lastname: Cheng
authors.forename: Ruo-Fan
authors.initials: RF
authors.lastname: Wang
mesh_terms: D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D054220:Malformations of Cortical Development / Q000150:complications*