title: Genital mycoplasmas in women attending the Yaoundé University Teaching Hospital in Cameroon.
abstract: Genital mycoplasmas are implicated in pelvic inflammatory diseases, puerperal infection, septic abortions, low birth weight, nongonococcal urethritis and prostatitis as well as spontaneous abortion and infertility in women. There is paucity of data on colonisation of genital mycoplasma in women and their drug sensitivity patterns. The aim of our study was to determine the prevalence of genital mycoplasmas (Ureaplasma urealiticumandMycoplasma hominis) infection and their drug sensitivity patterns in women. A mycofast kit was used for biochemical determination of mycoplasma infection in 100 randomly selected female patients aged 19-57 years, attending the University of Yaoundé Teaching Hospital (UYTH) from March to June 2010. Informed consent was sought and gained before samples were collected. Genital mycoplasmas were found in 65 patients (65%) [95% CI=55.7-74.3%] and distributed as 41 (41%) [95% CI=31.4-50.6%] forU. urealiticumand 4 (4%) [95% CI=0.20- 7.8%] forM. hominiswhile there was co-infection in 20 women (20%) [95% CI=12.16-27.84%]. In our study, 57 (57%) [95% CI=47.3-67%] had other organisms, which includedC. albicans(19 [19%]),G. vaginalis(35 [35%]) andT. vaginalis(3 [3%]). Among the 65 women with genital mycoplasma, the highest co-infection was withG. vaginalis(33.8%). Pristinamycine was the most effective antibiotic (92%) and sulfamethoxazole the most resistant (8%) antibiotic to genital mycoplasmas. We conclude that genital mycoplasma is a problem in Cameroon and infected women should be treated together with their partners.
authors.affiliation: Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Buea.
authors.forename: Anna L
authors.initials: AL
authors.lastname: Njunda
authors.affiliation: Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea.
authors.forename: Dickson S
authors.initials: DS
authors.lastname: Nsagha
authors.affiliation: Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea.
authors.forename: Jules C N
authors.initials: JC
authors.lastname: Assob
authors.affiliation: Department of Nursing, Faculty of Health Sciences, University of Buea.
authors.forename: John N
authors.initials: JN
authors.lastname: Palle
authors.affiliation: Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Buea.
authors.forename: Henri L
authors.initials: HL
authors.lastname: Kamga
authors.affiliation: Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea.
authors.forename: Peter F
authors.initials: PF
authors.lastname: Nde
authors.affiliation: Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Buea.
authors.forename: Mengang N C
authors.initials: MN
authors.lastname: Ntube
authors.affiliation: Department of Clinical Sciences, Faculty of Health Sciences, University of Buea, Cameroon.
authors.forename: Patrick E
authors.initials: PE
authors.lastname: Weledji
keywords: Cameroon.; drug sensitivity pattern; genital mycoplasma; women