title: Incidence of hidradenitis suppurativa in the United States: A sex- and age-adjusted population analysis.
abstract: BACKGROUND
  The true incidence of hidradenitis suppurativa (HS) is unknown.
  
  
  OBJECTIVE
  To determine standardized incidence estimates for HS in the United States.
  
  
  METHODS
  We used a retrospective cohort analysis, including incident HS cases identified using electronic health records data for a demographically heterogeneous population-based sample of >48 million unique patients across all 4 census regions. We calculated standardized 1- and 10-year cumulative incidences for the overall population and for sex-, age-, and race-specific groups.
  
  
  RESULTS
  There were 5410 new HS diagnoses over a 1-year period, with an incidence of 11.4 (95% confidence interval [CI], 11.1-11.8) cases per 100,000 population. One-year incidence in women was 16.1 (95% CI, 15.5-16.6) per 100,000, more than twice that of men [6.8 (95% CI, 6.5-7.2) per 100,000; P < .0001]. Age group-specific incidence was highest among patients 18 to 29 years of age [22.0 (95% CI, 21.0-23.2) per 100,000]. Incidence among African Americans [30.6 (95% CI, 29.1-32.2) per 100,000] was >2.5 times that of whites [11.7 (95% CI, 11.3-12.2) per 100,000; P < .0001]. The average annual overall incidence over 10 years was 8.6 (95% CI, 8.6-8.7) per 100,000 population.
  
  
  CONCLUSIONS
  The use of deidentified claims prevented validation for a larger case subset.
  
  
  CONCLUSIONS
  HS incidence has increased over the past decade and disproportionately involves women, young adults, and African Americans.
authors.affiliation: Department of Dermatology, Hofstra Northwell School of Medicine, New Hyde Park, New York. Electronic address: amgarg@northwell.edu.
authors.forename: Amit
authors.initials: A
authors.lastname: Garg
authors.affiliation: Department of Dermatology, Hofstra Northwell School of Medicine, New Hyde Park, New York.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Lavian
authors.affiliation: Department of Dermatology, Hofstra Northwell School of Medicine, New Hyde Park, New York.
authors.forename: Gloria
authors.initials: G
authors.lastname: Lin
authors.affiliation: Department of Dermatology, Hofstra Northwell School of Medicine, New Hyde Park, New York.
authors.forename: Andrew
authors.initials: A
authors.lastname: Strunk
authors.affiliation: Department of Dermatology, Hofstra Northwell School of Medicine, New Hyde Park, New York.
authors.forename: Allireza
authors.initials: A
authors.lastname: Alloo
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D017497:Hidradenitis Suppurativa / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D044469:Racial Groups; D012189:Retrospective Studies; D017678:Sex Distribution; D014481:United States / Q000453:epidemiology; D055815:Young Adult
keywords: African American; cumulative; epidemiology; hidradenitis suppurativa; incidence