title: Factors associated with study completion in patients with premature acute coronary syndrome.
abstract: BACKGROUND
  Factors associated with study completion in younger adults are not well understood. This study sought to describe psychosocial, clinical, and demographic features associated with completion of a study of men and women with premature acute coronary syndrome.
  
  
  METHODS
  As part of the GENdEr and Sex determInantS of cardiovascular disease: From bench to beyond-Premature Acute Coronary Syndrome (GENESIS-PRAXY) study, demographic, psychosocial, and clinical variables were assessed in 1213 patients hospitalized for acute coronary syndrome (≤ 55 years; 30% women). Patients were followed for 12 months. Dropouts withdrew from the study or were lost to follow-up after 12 months; completers were still enrolled after 12 months.
  
  
  RESULTS
  Of 1213 patients initially enrolled, 777 (64.1%) completed 12-month follow-up. Fully adjusted models suggested that being older (OR = 1.04, 95% CI [1.01, 1.06]), higher subjective social status within one's country (OR = 1.11, 95% CI [1.01, 1.22]), being free of type II diabetes, (OR = 0.66, 95% CI [0.45, 0.97]), non-smoking status (OR = 0.70, 95% CI [0.51, 0.95]) and being free of depression (OR = 1.52, 95% CI [1.11, 2.07]) were independently associated with study completion.
  
  
  CONCLUSIONS
  Recruitment/retention strategies targeting individuals who smoke, are younger, have low subjective social status within one's country, have diabetes, or have depression may improve participant follow-up in cardiovascular cohort studies.
authors.affiliation: Department of Social and Behavioral Sciences, University of Arkansas at Pine Bluff, Pine Bluff, Arkansas, United States of America.
authors.forename: Anthony W
authors.identifier: http://orcid.org/0000-0002-3275-5948
authors.initials: AW
authors.lastname: Austin
authors.affiliation: Centre de psychologie Au fil des maux, Mont-Saint-Hilaire, Quebec, Canada.
authors.forename: Roxanne
authors.initials: R
authors.lastname: Pelletier
authors.affiliation: Divisions of General Internal Medicine and Clinical Epidemiology, McGill University Health Centre, Montréal, Quebec, Canada.
authors.forename: Louise
authors.initials: L
authors.lastname: Pilote
authors.affiliation: Departments of Medicine, Community Health and Cardiac Sciences, University of Calgary, Calgary, Alberta, Canada.
authors.forename: Doreen M
authors.initials: DM
authors.lastname: Rabi
mesh_terms: D054058:Acute Coronary Syndrome / Q000523:psychology*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged