title: Biomarkers of cardiovascular and metabolic diseases in otherwise healthy overweight subjects in Bangladesh.
abstract: Biomarkers of cardiovascular and metabolic diseases were assessed in Bangladeshi overweight subjects categorized by Asian BMI criteria. After screening 300 people, 90 apparently healthy subjects were enrolled and grouped into normal weight, overweight and obese. Compared to normal weight, the overweight and obese groups showed significant elevation of serum triglyceride, insulin, homocysteine, insulin resistance/sensitivity, and atherogenic index of plasma. Cardiometabolic biomarkers did not differ between overweight and obese groups. Some biomarkers showed correlation with BMI in overweight but not in obese group. It was concluded that cardiometabolic biomarkers are elevated in Bangladeshi overweight subjects categorized by Asian BMI criteria.
authors.affiliation: Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh.
authors.forename: Kuenzang
authors.initials: K
authors.lastname: Chhezom
authors.affiliation: Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh.
authors.forename: M Iqbal
authors.initials: MI
authors.lastname: Arslan
authors.affiliation: Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh.
authors.forename: Md Mozammel
authors.initials: MM
authors.lastname: Hoque
authors.affiliation: Department of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, Bangladesh. Electronic address: su.biswas@yahoo.com.
authors.forename: Subrata Kumar
authors.initials: SK
authors.lastname: Biswas
mesh_terms: D000328:Adult; D001459:Bangladesh; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006710:Homocysteine / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008297:Male; D008659:Metabolic Diseases / Q000097:blood*; D008875:Middle Aged; D050177:Overweight / Q000097:blood*; D014280:Triglycerides / Q000097:blood
chemical_list: D015415:Biomarkers; D007328:Insulin; D014280:Triglycerides; D006710:Homocysteine
keywords: Asian BMI cut-off; Biomarker; Cardiovascular disease; Metabolic disease; Obesity; Overweight