title: The Effect of a Muscle Weight-Bearing and Aerobic Exercise Program on the Body Composition, Muscular Strength, Biochemical Markers, and Bone Mass of Obese Patients Who Have Undergone Gastric Bypass Surgery.
abstract: The effect of an exercise program on the body composition, muscular strength (MS), biochemical markers, and bone mineral density (BMD) of individuals undergoing gastric bypass is unclear. We assessed lean mass (LM), MS, bone remodeling markers, and BMD before and after supervised weight-bearing and aerobic exercise training in obese patients who underwent Roux-en-Y gastric bypass (RYGB).
  
  
  
  This study included 37 obese patients (81.1% women, mean age 38.2 years, mean body mass index 42.4 ± 0.5 kg/m2). Whole body densitometry was used to evaluate pre- and postoperative BMD, total body fat, and LM. Serum calcium, parathyroid hormone, 25-hydroxyvitamin D, and bone remodeling markers were measured. MS was determined through the concentric 10 repetition maximum test. Postoperatively, participants were divided into two groups: the training group, who followed an exercise program (TG, n = 18), and the control group, who did not (CG, n = 19).
  
  
  
  After 1 year, the TG showed a lower decrease in total BMD and at the lumbar spine and right hip compared with the CG (p < 0.001). The TG had lower mass reduction and an increase in upper limb LM compared with the CG (both p < 0.05). There was no significant difference between groups in bone markers or calcium metabolism. MS was higher in the TG than the CG (p < 0.05).
  
  
  
  The supervised exercise program attenuated lumbar spine and right hip BMD loss and improved LM in the arms and overall MS but did not affect bone remodeling.
authors.affiliation: ICBS, University Center's of Belo Horizonte (UNI-BH), Professor Mario Werneck Avenue, 1685 Estoril, Belo Horizonte, MG, 30455-610, Brazil. campanhaversiani@gmail.com.
authors.forename: Luciana
authors.initials: L
authors.lastname: Campanha-Versiani
authors.affiliation: Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
authors.forename: Danielle Aparecida Gomes
authors.initials: DAG
authors.lastname: Pereira
authors.affiliation: Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
authors.forename: Giane Amorim
authors.initials: GA
authors.lastname: Ribeiro-Samora
authors.affiliation: Felício Rocho Hospital, Belo Horizonte, Brazil.
authors.forename: Adauto Versiani
authors.initials: AV
authors.lastname: Ramos
authors.affiliation: Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
authors.forename: Maria Fatima H
authors.initials: MFH
authors.lastname: de Sander Diniz
authors.affiliation: Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
authors.forename: Luiz Armando
authors.initials: LA
authors.lastname: De Marco
authors.affiliation: Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.|Felício Rocho Hospital, Belo Horizonte, Brazil.
authors.forename: Maria Marta Sarquis
authors.initials: MMS
authors.lastname: Soares
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001823:Body Composition; D015519:Bone Density; D015444:Exercise; D005081:Exercise Therapy; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D009767:Obesity, Morbid / Q000097:blood / Q000601:surgery / Q000628:therapy*; D016474:Weight-Bearing
chemical_list: D015415:Biomarkers
keywords: Bariatric surgery; Body composition; Bone; Bone remodeling; Densitometry; Exercise; Muscle strength; Obesity