title: Periorbital discoid lupus: a rare localization in a patient with systemic lupus erythematosus.
abstract: A 40-year-old female patient with a 5-year history of systemic lupus erythematosus was referred to our policlinic with complaints of erythema, atrophy, and telangiectasia on the upper eyelids for 8 months. No associated mucocutaneous lesion was present. Biopsy taken by our ophthalmology department revealed discoid lupus erythematosus. Topical tacrolimus was augmented to the systemic therapeutic regimen of the patient, which consisted of continuous antimalarial treatment and intermittent corticosteroid drugs. We observed no remission in spite of the 6-month supervised therapy. Periorbital discoid lupus erythematosus is very unusual and should be considered in the differential diagnosis of erythematous lesions of the periorbital area..
authors.affiliation: Istanbul Medeniyet University Goztepe Research and Training Hospital - Istanbul, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Cakici
authors.affiliation: Istanbul Medeniyet University School of Medicine - Istanbul, Turkey.
authors.forename: Remzi
authors.initials: R
authors.lastname: Karadag
authors.affiliation: Istanbul Medeniyet University School of Medicine - Istanbul, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Bayramlar
authors.affiliation: Istanbul Medeniyet University Goztepe Research and Training Hospital - Istanbul, Turkey.
authors.forename: Seyma
authors.initials: S
authors.lastname: Ozkanli
authors.affiliation: Istanbul Medeniyet University Goztepe Research and Training Hospital - Istanbul, Turkey.
authors.forename: Tugba Kevser
authors.initials: TK
authors.lastname: Uzuncakmak
authors.affiliation: Istanbul Medeniyet University School of Medicine - Istanbul, Turkey.
authors.forename: Ayse Serap
authors.initials: AS
authors.lastname: Karadag
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001706:Biopsy; D005141:Eyelid Diseases / Q000473:pathology*; D005143:Eyelids / Q000473:pathology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008179:Lupus Erythematosus, Discoid / Q000473:pathology*; D008180:Lupus Erythematosus, Systemic / Q000473:pathology*; D035583:Rare Diseases; D016559:Tacrolimus / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D016559:Tacrolimus