title: Intracardiac Fungal Mass in a Term Neonate.
abstract: Systemic fungal infections pose insidious challenges in neonatal intensive care settings. We present the case of a 9-day-old male term neonate admitted for polymicrobial sepsis and hepatic dysfunction who later developed candidemia superinfection. Despite broad antifungal therapy, the fungemia was complicated by progressive growth of a fungus ball in the right ventricular outflow tract that threatened cardiac function. Surgical excision of the mass was undertaken by right atriotomy and histologic examination confirmed Candida albicans.
authors.affiliation: Children's National Health System, Washington, DC; Zagazig University Faculty of Medicine, Zigzag, Egypt.
authors.forename: Magdy M
authors.initials: MM
authors.lastname: El-Sayed Ahmed
authors.affiliation: Children's National Health System, Washington, DC.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kurkluoglu
authors.affiliation: Children's National Health System, Washington, DC.
authors.forename: Conor F
authors.initials: CF
authors.lastname: Hynes
authors.affiliation: Children's National Health System, Washington, DC.
authors.forename: Darren
authors.initials: D
authors.lastname: Klugman
authors.affiliation: Children's National Health System, Washington, DC.
authors.forename: Elena
authors.initials: E
authors.lastname: Puscasiu
authors.affiliation: Children's National Health System, Washington, DC.
authors.forename: Dilip S
authors.initials: DS
authors.lastname: Nath
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002176:Candida albicans / Q000254:growth & development* / Q000302:isolation & purification; D002177:Candidiasis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006348:Cardiac Surgical Procedures; D017548:Echocardiography, Transesophageal; D006561:Herpes Simplex / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D018259:Herpesvirus 1, Human / Q000302:isolation & purification; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy / Q000821:virology; D007363:Intensive Care Units, Neonatal; D017093:Liver Failure / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D008297:Male; D015163:Superinfection; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy
chemical_list: D000935:Antifungal Agents; D000998:Antiviral Agents
keywords: Candida albicans; acute liver failure; fungemia; human herpesvirus 1