title: Independent component analysis-based source-level hyperlink analysis for two-person neuroscience studies.
abstract: Two-person neuroscience, a perspective in understanding human social cognition and interaction, involves designing immersive social interaction experiments as well as simultaneously recording brain activity of two or more subjects, a process termed “hyperscanning.” Using newly developed imaging techniques, the interbrain connectivity or hyperlink of various types of social interaction has been revealed. Functional near-infrared spectroscopy (fNIRS)-hyperscanning provides a more naturalistic environment for experimental paradigms of social interaction and has recently drawn much attention. However, most fNIRS-hyperscanning studies have computed hyperlinks using sensor data directly while ignoring the fact that the sensor-level signals contain confounding noises, which may lead to a loss of sensitivity and specificity in hyperlink analysis. In this study, on the basis of independent component analysis (ICA), a source-level analysis framework is proposed to investigate the hyperlinks in a fNIRS two-person neuroscience study. The performance of five widely used ICA algorithms in extracting sources of interaction was compared in simulative datasets, and increased sensitivity and specificity of hyperlink analysis by our proposed method were demonstrated in both simulative and real two-person experiments.
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing, China.
authors.forename: Rui-Na
authors.initials: RN
authors.lastname: Dai
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Xiao
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing, China.
authors.forename: Zong
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing, China.
authors.forename: Lian
authors.initials: L
authors.lastname: Duan
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing, ChinabBeijing Normal University, Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
authors.affiliation: Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing, ChinabBeijing Normal University, Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing, China.
authors.forename: Chao-Zhe
authors.initials: CZ
authors.lastname: Zhu
mesh_terms: D000465:Algorithms; D001931:Brain Mapping; D006801:Humans; D007398:Interpersonal Relations; D009488:Neurosciences / Q000295:instrumentation* / Q000379:methods*; D019265:Spectroscopy, Near-Infrared