title: The use status of anticoagulation drugs for inpatients with nonvalvular atrial fibrillation in Southwest China.
abstract: BACKGROUND
  Oral anticoagulants (OACs) are effective for the prophylaxis of stroke in patients with atrial fibrillation (AF). This cross-sectional study aimed to investigate the status of anticoagulation treatment for hospitalized AF patients in Southwest China.
  
  
  METHODS
  A total of 4760 hospitalized patients with AF were enrolled from 21 hospitals in Chongqing city from January 1 to December 31, 2013.
  
  
  RESULTS
  Among the enrolled patients, 3785 were diagnosed with nonvalvular AF. These patients had a mean age of 74.4±10.1 years. The mean CHADS2score of all subjects was 2.60±1.34, and 80.7% of the patients had CHADS2≥2. The use rate of OACs was only 11.5% for patients with a high risk for stroke (CHADS2≥2) and was much lower in patients from the second-level hospitals than in patients from the third-level hospitals (5.8% vs. 16.9%,P<0.001). The leading reason for the underuse of OACs in high-risk patients was physician's nonfeasance.
  
  
  CONCLUSIONS
  This study demonstrated that the underuse of anticoagulation therapy in hospitalized patients with nonvalvular AF was particularly serious in Southwest China, especially in the second-level hospitals. Urgent and effective measures are desperately needed to improve this alarming situation in China.
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
authors.forename: Huan Jie
authors.initials: HJ
authors.lastname: Zheng
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
authors.forename: Shu Kun
authors.initials: SK
authors.lastname: Ouyang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
authors.forename: Kai
authors.initials: K
authors.lastname: Lu
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
authors.forename: Su Xin
authors.initials: SX
authors.lastname: Luo
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
authors.forename: Hua
authors.initials: H
authors.lastname: Xiao
keywords: anticoagulation therapy; antiplatelet therapy; atrial fibrillation; international normalized ratio; oral anticoagulant