title: Mycoplasma hominis periaortic abscess following heart-lung transplantation.
abstract: We report the first case of Mycoplasma hominis periaortic abscess after heart-lung transplantation. The absence of sternal wound infection delayed the diagnosis, but the patient successfully recovered with debridement surgeries and long-term antibiotic therapy. Owing to the difficulty in detection and the intrinsic resistance to beta-lactams, M. hominis infections are prone to being misdiagnosed and undertreated. M. hominis should be suspected in cases where conventional microbiological identification and treatment approaches fail.
authors.affiliation: Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Hideharu
authors.identifier: http://orcid.org/0000-0002-5086-1891
authors.initials: H
authors.lastname: Hagiya
authors.affiliation: Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Hisao
authors.initials: H
authors.lastname: Yoshida
authors.affiliation: Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Norihisa
authors.initials: N
authors.lastname: Yamamoto
authors.affiliation: Laboratory for Clinical Investigation, Osaka University Hospital, Osaka, Japan.
authors.forename: Keigo
authors.initials: K
authors.lastname: Kimura
authors.affiliation: Laboratory for Clinical Investigation, Osaka University Hospital, Osaka, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Ueda
authors.affiliation: Laboratory for Clinical Investigation, Osaka University Hospital, Osaka, Japan.
authors.forename: Isao
authors.initials: I
authors.lastname: Nishi
authors.affiliation: Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Akeda
authors.affiliation: Department of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Tomono
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001999:Bronchoscopy; D002313:Cardiomyopathy, Restrictive / Q000601:surgery*; D003646:Debridement / Q000379:methods; D004417:Dyspnea / Q000188:drug therapy / Q000382:microbiology; D005938:Glucocorticoids / Q000627:therapeutic use; D006084:Graft Rejection / Q000000981:diagnostic imaging / Q000628:therapy; D016041:Heart-Lung Transplantation / Q000009:adverse effects*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000601:surgery*; D064704:Levofloxacin / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008911:Minocycline / Q000627:therapeutic use; D019535:Mycoplasma hominis / Q000302:isolation & purification / Q000472:pathogenicity* / Q000502:physiology; D009325:Nausea / Q000139:chemically induced; D010956:Plasmapheresis; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy; D013249:Sternum / Q000601:surgery; D013530:Surgical Wound Infection / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D055815:Young Adult; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D064704:Levofloxacin; D001618:beta-Lactamases; D008911:Minocycline; D008775:Methylprednisolone
keywords: 
  Mycoplasma hominis
  ; extragenital infection; mediastinitis; periaortic abscess; transplantation