title: Early Results of Rheumatic Mitral Valve Repair.
abstract: Mitral valve repair (MVr) in rheumatic heart disease (RHD) remains challenging. The present authors' surgical experience of MVr in 56 patients with RHD operated in between January 2011 and September 2014 is reported.
  
  
  
  Among the patients (mean age 32 ± 11 years), 11 were in NYHA functional class II, 32 in class III, and seven in class IV. An adequate or oversized autologous pericardial patch was sutured to extend the coaptating edge of both the anterior leaflet (in 18 patients) and the posterior leaflet (in 30 patients). Neochordae were implanted as needed (n = 43), and leaflet thinning (n = 13), commissurotomy (n = 15) and chordal splitting (n = 9) were also performed. A rigid annuloplasty ring was implanted in 32 patients, and in 24 patients a complete flexible annuloplasty ring made from pericardium, 4 mm Gore-Tex tube graft or a Dacron patch was constructed. Repair was not attempted in 16 patients, with replacement using a mechanical bileaflet prosthesis being considered the only option.
  
  
  
  Intraoperative post-repair transesophageal echocardiography demonstrated competency, with trivial mitral regurgitation (MR) up to grade I in all patients and a minimum coaptation depth ≥5 mm. There were no intraoperative or in-hospital deaths. Clinical and echocardiographic evaluations were performed up to six weeks after surgery, at which time 51 patients were in NYHA classes I-II and five were in class III. Residual mild MR up to grade I was identified in six patients. No recurrence of MR was observed in any of the patients, and no patients were reoperated on.
  
  
  
  The lack of adequate access to anticoagulation medication and monitoring, in addition to religious/cultural bias to the type of prosthetic valve used in low-income countries, necessitates an increase in the numbers of rheumatic MVr.
authors.affiliation: Cardiothoracic Department, Hammersmith Hospital, Imperial College, London, UK. Electronic correspondence: dottpetrone@libero.it.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Petrone
authors.affiliation: Cardiothoracic Department, Hammersmith Hospital, Imperial College, London, UK.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Theodoropoulos
authors.affiliation: Cardiothoracic Department, Hammersmith Hospital, Imperial College, London, UK.
authors.forename: Prakash P
authors.initials: PP
authors.lastname: Punjabi
mesh_terms: D000328:Adult; D058385:Cardiac Valve Annuloplasty / Q000379:methods*; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000601:surgery*; D012214:Rheumatic Heart Disease / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult