title: The Oldham Notebooks: an analysis of the development of IVF 1969-1978. II. The treatment cycles and their outcomes.
abstract: This paper reports on the numbers of treatment cycles involved in the development of IVF (1969-1978) and their outcomes. We show that between 1969 and 1978: (i) a minimum of 282 women were involved in 495 cycles of potential laparoscopic oocyte retrieval (LOR); (ii) of these cycles, 457/495 proceeded to LOR to attempt egg collection; (iii) of which an outcome was recorded in 436/457; (iv) eggs were recovered in 388/436 of these; (v) inseminations were recorded in 331/388; (vi) embryos were recorded in at least 167; (vii) a total of 112 embryo transfers were attempted; and (viii) a maximum of 11 possible biochemical/preclinical pregnancies plus five clinical pregnancies were observed; (ix) from which two healthy live births resulted.
authors.affiliation: Bourn Hall Clinic, Bourn, Cambridge CB23 2TN.
authors.forename: Kay
authors.initials: K
authors.lastname: Elder
authors.affiliation: Anatomy School and Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, Downing Street, Cambridge CB2 3DY, UK.
authors.forename: Martin H
authors.initials: MH
authors.lastname: Johnson
keywords: embryo transfers; fertilisation rates; history of IVF; laparoscopic oocyte retrieval; pregnancy outcomes