title: Antibacterial Activity of Metabolites Products ofVibrio AlginolyticusIsolated from SpongeHaliclonasp. AgainstStaphylococcus Aureus.
abstract: The objective of this study was to investigate the antibacterial activity of primary and secondary metabolites fromVibrio alginoliticusisolated from spongeHaliclonasp. againstStaphylococcus aureus. A descriptive method was used in this research. The antibacterial activity was analysed by paper disk method. The results showed that the primary metabolites produced byVibrio alginoliticusthat is in symbiosis with spongeHaliclonasp. were able to effectively inhibitStaphylococcus aureusgrowth with an inhibition zone diameter of 12.9 mm, while the secondary metabolites of 9.9 mm. Electrophoresis analysis of the primary metabolites showed that there were 11 protein bands which were not found in secondary metabolites. Protein bands with low molecular weights presumably had an inhibiting effect on the growth ofStaphylococcus aureus.
authors.affiliation: Faculty of Fisheries and Marine Sciences, University of Brawijaya , Malang, Indonesia.
authors.forename: Happy
authors.initials: H
authors.lastname: Nursyam
keywords: Antibacterial activity; Haliclona sp; Primary metabolite; Secondary metabolite; Vibrio algo-noliticus