title: Potential application of the Kampo medicine goshajinkigan for prevention of chemotherapy-induced peripheral neuropathy.
abstract: Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common and severe adverse effects related to cancer treatment. Unfortunately, although several agents and protocols have been proposed, no prophylactic strategies have yet to be proven useful. Therefore, new alternative therapies have been considered for CIPN prevention. Herbal medicine in Japan, called Kampo medicine, is derived from traditional Chinese medicine. Goshajinkigan (GJG) is a Kampo medicine, that is comprised of ten herbs. The aim of this work is to analyse the results of pre-clinical and clinical studies on the potential applications of GJG in CIPN prevention.
authors.affiliation: Division of Anesthesia, Department of Anesthesia and Pain Medicine, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, via Mariano Semmola, Naples 80131, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Cascella
authors.affiliation: Division of Infantile Neuropsychiatry, UOMI-Maternal and Infant Health, Asl NA 3 SUD, Torre del Greco, via Marconi, Naples 80059, Italy.
authors.forename: Maria Rosaria
authors.initials: MR
authors.lastname: Muzio
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D020835:Medicine, Kampo; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced / Q000517:prevention & control*; D008517:Phytotherapy
chemical_list: D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; C119642:gosha-jinki-gan