title: Optimal timing for performing hysterectomy according to different phase of menstrual cycle: Which is best?
abstract: The aim of this study was to determine whether the different phases of the menstrual cycle could affect operative bleeding in women undergoing laparoscopic hysterectomy. This was a retrospective comparative study. Based on the adjusted day of menstrual cycle, 212 women who underwent laparoscopic hysterectomy were classified into three groups: the follicular phase (n = 51), luteal phase group (n = 125), and menstruation group (n = 36). The primary outcome measure was the operative bleeding. There was no difference in the baseline characteristics of the patients belonging to the three groups. For the groups, there were no significant differences in operative bleeding (p = .469) and change in haemoglobin (p = .330), including operative time, length of hospital stay and complications. The menstrual cycle did not affect the operative bleeding and other parameters. Therefore, no phase of the menstrual cycle could be considered as an optimal timing for performing laparoscopic hysterectomy with minimal operative bleeding. Impact statement What is already known on this subject: the menstrual cycle results in periodic changes in haemostasis and blood flow in the reproductive organs. What the results of this study add: the menstrual cycle did not affect the operative bleeding and other operative parameters during laparoscopic hysterectomy. What the implications are of these findings for clinical practice and/or further research: no phase of the menstrual cycle could be considered as an optimal timing for performing laparoscopic hysterectomy with minimal operative bleeding.
authors.affiliation: a Department of Obstetrics and Gynecology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Republic of Korea.
authors.forename: Jeong Jin
authors.initials: JJ
authors.lastname: Kim
authors.affiliation: a Department of Obstetrics and Gynecology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Republic of Korea.
authors.forename: Jun Hyeok
authors.initials: JH
authors.lastname: Kang
authors.affiliation: a Department of Obstetrics and Gynecology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Republic of Korea.
authors.forename: Kyo Won
authors.initials: KW
authors.lastname: Lee
authors.affiliation: a Department of Obstetrics and Gynecology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Republic of Korea.
authors.forename: Kye Hyun
authors.initials: KH
authors.lastname: Kim
authors.affiliation: a Department of Obstetrics and Gynecology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Republic of Korea.
authors.forename: Taejong
authors.initials: T
authors.lastname: Song
mesh_terms: D016063:Blood Loss, Surgical; D005260:Female; D005498:Follicular Phase; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects / Q000379:methods*; D010535:Laparoscopy; D007902:Length of Stay; D008183:Luteal Phase; D008598:Menstruation; D008875:Middle Aged; D061646:Operative Time; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D012189:Retrospective Studies; D013997:Time Factors
keywords: Haemorrhage; hysterectomy; laparoscopy; menstrual cycle; surgical procedures