title: Linear IgA and IgG bullous dermatosis.
abstract: Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be considered a subtype of this dermatosis or a new entity. Further studies are needed to recognize this clinical variant.
authors.affiliation: Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.
authors.forename: Karina de Almeida Pinto
authors.initials: KA
authors.lastname: Fernandes
authors.affiliation: Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.
authors.forename: Kely Hernández
authors.initials: KH
authors.lastname: Galvis
authors.affiliation: Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.
authors.forename: Anndressa Camillo da Matta Setubal
authors.initials: AC
authors.lastname: Gomes
authors.affiliation: Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.
authors.forename: Osvania Maris
authors.initials: OM
authors.lastname: Nogueira
authors.affiliation: Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.|Hospital Federal dos Servidores do Estado (HFSE) - Rio de Janeiro (RJ), Brazil.
authors.forename: Paulo Antônio Oldani
authors.initials: PA
authors.lastname: Felix
authors.affiliation: Hospital Federal de Bonsucesso (HFB) -Rio de Janeiro (RJ), Brazil.
authors.forename: Thiago Jeunon de Sousa
authors.initials: TJ
authors.lastname: Vargas
mesh_terms: D001485:Basement Membrane / Q000473:pathology; D001706:Biopsy; D002648:Child; D004890:Erythema / Q000473:pathology; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D062027:Linear IgA Bullous Dermatosis / Q000473:pathology*; D008297:Male; D012867:Skin / Q000473:pathology*; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology