title: Importance of Propellants and Excipients in Pharmaceutical Topical Aerosol.
abstract: Skin is the most suitable and recommendable organ of the human body for topical administration and the main route for topical drug delivery system. Drug delivery system is the methodology used to ensure the entry of drugs into the body, reaching their target for pharmacological action. Patients tend to prefer the painless route for drug administration. So, pharmaceutical aerosols came to existence to meet patient compliance. Many variations in excipients with respect to compatibility to drugs, stability and economy are being used to improve the aerosol system of drug delivery. The present review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
  
  
  CONCLUSIONS
  The review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
  
  
  CONCLUSIONS
  Presently, aerosol drug delivery system has become beneficial as far as faster pharmacological action and economy are concerned. Other than the active pharmaceutical ingredient (API), the pharmacological action of the aerosol system is also dependent on the excipients used as they help the API to penetrate through the skin as fast as possible.
authors.affiliation: Abbess Healthcare OPC Pvt. Ltd., Kandivili East, Mumbai - 400101. India.
authors.forename: Maunab
authors.initials: M
authors.lastname: Patra
authors.affiliation: Abbess Healthcare OPC Pvt. Ltd., Kandivili East, Mumbai - 400101. India.
authors.forename: Sibasis
authors.initials: S
authors.lastname: Bhattacharya
authors.affiliation: Abbess Healthcare OPC Pvt. Ltd., Kandivili East, Mumbai - 400101. India.
authors.forename: Meenakshi
authors.initials: M
authors.lastname: Patnaik
mesh_terms: D000287:Administration, Topical; D000336:Aerosols / Q000008:administration & dosage* / Q000737:chemistry*; D016503:Drug Delivery Systems; D005079:Excipients / Q000737:chemistry*; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry*; D012869:Skin Absorption / Q000187:drug effects*
chemical_list: D000336:Aerosols; D005079:Excipients; D004364:Pharmaceutical Preparations
keywords: Excipients; pharmaceutical aerosol; propellants; skin; solvents; topical drug delivery system