title: Chronic Mesenteric Ischemia: Patient Outcomes Using Open Surgical Revascularization.
abstract: BACKGROUND
  Chronic mesenteric ischemia (CMI) is a rare disease. Open treatment (OT) remains a valuable treatment option. We analyzed patient outcomes after OT and investigated health-related quality of life (HRQoL).
  
  
  METHODS
  Data were analyzed retrospectively. The investigation period was from January 1, 2001, to December 31, 2014. We investigated mortality and patency rates using Kaplan-Meier analysis. HRQoL was measured using a 36-item health survey. Various statistical methods were employed.
  
  
  RESULTS
  A total of 100 patients (celiac trunk [TC: n = 23], superior mesenteric artery [SMA: n = 26], or both [n = 51]) were included. Median follow-up was 5 ± 35 months. One-year survival rate for TC was 75 ± 11%, for SMA: 79 ± 10%, and for both: 96 ± 3%. TC 5-year survival was 75 ± 11% (SMA: 57 ± 16%: both: 80 ± 8%). Obesity and the length of hospital stay were independently associated with patient survival (p < 0.05). Primary 1-year patency rate was 60 ± 13% for TC (SMA: 86 ± 10%; both: 71 ± 8%) and secondary 1-year patency rate was 84 ± 9% for TC (SMA: 100%; both: 79 ± 7%). HRQoL was inferior compared to the German normative data (p < 0.05).
  
  
  CONCLUSIONS
  CMI overlaps between gastrointestinal and vascular surgery. OT is safe, and simultaneous revascularization of the TC and the SMA does not affect mortality. Patients would not necessarily benefit from OT in terms of HRQoL.
authors.affiliation: Department of Vascular and Endovascular Surgery, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
authors.forename: Markus U
authors.initials: MU
authors.lastname: Wagenhäuser
authors.forename: Yvonne K
authors.initials: YK
authors.lastname: Meyer-Janiszewski
authors.forename: Philip
authors.initials: P
authors.lastname: Dueppers
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Spin
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Floros
authors.forename: Hubert
authors.initials: H
authors.lastname: Schelzig
authors.forename: Mansur
authors.initials: M
authors.lastname: Duran
mesh_terms: D000368:Aged; D002445:Celiac Artery / Q000601:surgery*; D002908:Chronic Disease; D004691:Endarterectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007902:Length of Stay; D008297:Male; D017538:Mesenteric Artery, Superior / Q000601:surgery*; D065666:Mesenteric Ischemia / Q000150:complications / Q000601:surgery*; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011788:Quality of Life; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D058017:Vascular Grafting; D014654:Vascular Patency
keywords: Chronic mesenteric ischemia; Coeliac trunk; Health-related quality of life; Open surgical treatment; Superior mesenteric artery