title: Mutations of early neurogenesis inDrosophila.
abstract: Embryonic lethal mutations at the Notch locus are known to produce a conspicuous central nervous system hypertrophy accompanied by a hypotrophy of the epidermal sheath. We have studied several zygotic mutants belonging to four different autosomal complementation groups which produce the same phenotype. The embryonic development of the new mutants, as well as that of Notch, consists of an initial enlargement of the neurogenic region at the expenses of epidermal cell precursors. The possibility is discussed that these five loci are involved in the determination of neural and epidermal cell precursors.
authors.affiliation: Institut für Biologie III, Schäzlestraße 1, 7800, Freiburg i. Br., Germany.
authors.forename: Ruth
authors.initials: R
authors.lastname: Lehmann
authors.affiliation: Institut für Biologie III, Schäzlestraße 1, 7800, Freiburg i. Br., Germany.
authors.forename: Ursula
authors.initials: U
authors.lastname: Dietrich
authors.affiliation: Institut für Biologie III, Schäzlestraße 1, 7800, Freiburg i. Br., Germany.
authors.forename: F
authors.initials: F
authors.lastname: Jiménez
authors.affiliation: Institut für Biologie III, Schäzlestraße 1, 7800, Freiburg i. Br., Germany.
authors.forename: J A
authors.initials: JA
authors.lastname: Campos-Ortega
keywords: Drosophila melanogaster; Early neurogenesis; Mutants