title: Necrotizing Polyarteritis Nodosa-like Vasculitis in a Child with Systemic Lupus Erythematosus.
abstract: A 10-year-old child presented with prolonged fever, lymphadenopathy, weight loss, oral ulcers, alopecia and parotitis. She later developed arterial thrombosis, poly-serositis, nephritis, myocarditis, sacro-ilitis, autoimmune hemolytic anemia and refractory thrombocytopenia. Though anti-dsDNA was negative, she was diagnosed to have systemic lupus erythematosus (SLE). Terminally, she had pulmonary symptoms and succumbed to her illness. The autopsy showed lupus nephritis-Class II, polyserositis, myocarditis, inflammatory myositis, immune mediated vasculitis involving renal, coronary, pancreatic, adrenal, dermal and intramuscular arteries, and pulmonary hemorrhages and edema.
authors.affiliation: Departments of Pediatrics and *Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Ritambhra
authors.initials: R
authors.lastname: Nada
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Matthews
authors.forename: Sagar
authors.initials: S
authors.lastname: Bhattad
authors.forename: Anju
authors.initials: A
authors.lastname: Gupta
authors.forename: Surjit
authors.initials: S
authors.lastname: Singh
mesh_terms: D002648:Child; D017809:Fatal Outcome; D005260:Female; D005335:Fever of Unknown Origin; D006801:Humans; D008180:Lupus Erythematosus, Systemic; D010488:Polyarteritis Nodosa; D013921:Thrombocytopenia; D014657:Vasculitis