title: Fluctuations in the amplitude of ST-segment elevation in vasospastic angina: Two case reports.
abstract: BACKGROUND
  ST-segment elevation localizes an ischemic lesion to the coronary artery supplying the area of the myocardium reflected by the electrocardiographic leads. Dynamic ST-segment elevation can be due to severe transmural ischemia secondary to a thrombus, vasospasm, or a tightly fixed coronary artery lesion or a combination of these situations.
  
  
  METHODS
  In this study, we report on two patients with angina who had fluctuations in ST-segment amplitude on serial electrocardiograms. The amplitude of ST-segment elevation varied between 1-20 mm.
  
  
  METHODS
  Vasospastic angina (VSA) was diagnosed based on electrocardiography and coronary angiography.
  
  
  METHODS
  Calcium antagonists were prescribed for both patients.
  
  
  RESULTS
  No recurrent VSA was noted during outpatient follow-up.
  
  
  CONCLUSIONS
  VSA can be associated with fluctuations in the amplitude of ST-segment elevation, indicating dynamic coronary vasospasm in different locations and extensions in patients with VSA.
authors.affiliation: Section of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Chang Gung University College of Medicine, Keelung City, Taiwan.
authors.forename: Ming-Jui
authors.initials: MJ
authors.lastname: Hung
mesh_terms: D000368:Aged; D000788:Angina Pectoris, Variant / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D003329:Coronary Vasospasm / Q000503:physiopathology; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002121:Calcium Channel Blockers