title: Ru(ii)-Pheox-catalyzed Si-H insertion reaction: construction of enantioenriched carbon and silicon centers.
abstract: We established a highly enantioselective Si-H insertion reaction to construct chiral centers at the carbon and silicon atoms, using a Ru(ii)-pheox catalyst. The catalytic asymmetric Si-H insertion reaction of α-methyl-α-diazoesters proceeded smoothly with excellent stereoinduction at both the neighboring carbon and silicon atoms (up to 99% yield and 99% ee).
authors.affiliation: Department of Environmental and Life Sciences, Toyohashi University of Technology, 1-1 Tempaku-cho, Toyohashi, Aichi 441-8580, Japan. cs008@edu.imc.tut.ac.jp iwasa@ens.tut.ac.jp.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Nakagawa
authors.affiliation: Department of Environmental and Life Sciences, Toyohashi University of Technology, 1-1 Tempaku-cho, Toyohashi, Aichi 441-8580, Japan. cs008@edu.imc.tut.ac.jp iwasa@ens.tut.ac.jp.
authors.forename: Soda
authors.identifier: http://orcid.org/0000-0001-6313-4784
authors.initials: S
authors.lastname: Chanthamath
authors.affiliation: Department of Environmental and Life Sciences, Toyohashi University of Technology, 1-1 Tempaku-cho, Toyohashi, Aichi 441-8580, Japan. cs008@edu.imc.tut.ac.jp iwasa@ens.tut.ac.jp.
authors.forename: Ikuhide
authors.initials: I
authors.lastname: Fujisawa
authors.affiliation: Department of Environmental and Life Sciences, Toyohashi University of Technology, 1-1 Tempaku-cho, Toyohashi, Aichi 441-8580, Japan. cs008@edu.imc.tut.ac.jp iwasa@ens.tut.ac.jp.
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Shibatomi
authors.affiliation: Department of Environmental and Life Sciences, Toyohashi University of Technology, 1-1 Tempaku-cho, Toyohashi, Aichi 441-8580, Japan. cs008@edu.imc.tut.ac.jp iwasa@ens.tut.ac.jp.
authors.forename: Seiji
authors.initials: S
authors.lastname: Iwasa