title: [Maternal use of non-steroidal antiinflammatory drugs and closure of the ductus arteriosus].
abstract: We report a case of intrauterine premature closure of the ductus arteriosus diagnosed in an anasarca fetus associated with major heart failure following mother's ingestion of non-steroidal anti-inflammatory drugs (NSAID). Second trimester obstetric ultrasound allowed detection of an asymmetry of the cardiac chambers. Caesarean section was perfomed at 30 weeks of pregnancy to remove anasarca fetus with major heart failure due to prenatal closure of the ductus arteriosus. Based upon this case, we conducted a literature review to highlight potential fetal and neonatal complications resulting from early closure of the ductus arteriosus secondary to NSAID use during pregnancy.
authors.affiliation: Service de Néonatologie et Réanimation Néonatale, Centre Hospitalier Universitaire Albert Royer Dakar, Université Cheikh Anta Diop de Dakar BP: 5005 Dakar-Fann, Sénégal.
authors.forename: Daouda Diamane
authors.initials: DD
authors.lastname: Ndour
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D002585:Cesarean Section; D004373:Ductus Arteriosus / Q000000981:diagnostic imaging / Q000187:drug effects*; D005260:Female; D005318:Fetal Heart / Q000000981:diagnostic imaging / Q000503:physiopathology; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D016216:Ultrasonography, Prenatal / Q000379:methods
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal
keywords: Intrauterine premature closure of the ductus arteriosus; NSAID; fetal anasarca; heart failure