title: One-Stage Exchange Arthroplasty: A Surgical Technique Update.
abstract: Standard surgical treatment for a periprosthetic knee infection has been based on a staged surgical technique, in order to assure infection eradication prior to implantation of a new prosthesis.
  
  
  
  In this article, we discuss our surgical technique in undertaking a single-stage exchange of a chronic knee periprosthetic infection.
  
  
  
  This technique, which is based on the fundamental principles of controlling infection, preventing recurrence, and restoring function, has been shown to deliver high success rates.
  
  
  
  As demonstrated, when undertaken under appropriate circumstances, a single-stage exchange combined with local and systemic antibiotic delivery can result in infection eradication comparable to a 2-staged exchange.
authors.affiliation: Department of Trauma and Orthopaedics, University College London Hospitals, London, United Kingdom.
authors.forename: David A
authors.initials: DA
authors.lastname: George
authors.affiliation: Department of Trauma and Orthopaedics, University College London Hospitals, London, United Kingdom.
authors.forename: Fares S
authors.initials: FS
authors.lastname: Haddad
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D007720:Knee Prosthesis; D016459:Prosthesis-Related Infections / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents
keywords: exchange arthroplasty; knee joint infection; one stage; single stage; surgical technique