title: What's unique about acute pancreatitis in children: risk factors, diagnosis and management.
abstract: Pancreatitis in children is an appreciable problem that has become increasingly prevalent. This Review covers the principles related to the definitions, epidemiology, risk factors, diagnosis and management of acute pancreatitis in children and identifies features that are unique among children. Additionally, knowledge gaps related to management principles are identified.
authors.affiliation: Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pediatrics, 4401 Penn Avenue, Pittsburgh, Pennsylvania 15224, USA.
authors.forename: Sohail Z
authors.initials: SZ
authors.lastname: Husain
authors.affiliation: Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pediatrics, 4401 Penn Avenue, Pittsburgh, Pennsylvania 15224, USA.
authors.forename: Arvind I
authors.initials: AI
authors.lastname: Srinath
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000208:Acute Disease; D000681:Amylases / Q000378:metabolism; D000975:Antioxidants / Q000627:therapeutic use; D002352:Carrier Proteins / Q000235:genetics; D002648:Child; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002763:Cholecystectomy / Q000379:methods; D002918:Chymotrypsin / Q000235:genetics; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D018450:Disease Progression; D005440:Fluid Therapy / Q000379:methods; D006760:Hospitalization; D006801:Humans; D008049:Lipase / Q000378:metabolism; D018529:Nutritional Support / Q000379:methods; D010195:Pancreatitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D012307:Risk Factors; D014357:Trypsin / Q000235:genetics; D014359:Trypsin Inhibitor, Kazal Pancreatic
chemical_list: D000975:Antioxidants; C505032:CFTR protein, human; D002352:Carrier Proteins; C486642:SPINK1 protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D014359:Trypsin Inhibitor, Kazal Pancreatic; D008049:Lipase; D000681:Amylases; D002918:Chymotrypsin; C117569:chymotrypsin C; C489303:PRSS1 protein, human; D014357:Trypsin