title: [Endovascular treatment of acute iliofemoral deep venous thrombosis - our results with catheter-directed thrombolysis and AngioJet].
abstract: Most of the patients with iliofemoral thrombosis treated with anticoagulants only are affected with postthrombotic syndrome (PTS) that worsens the patients' quality of life. In the acute phase of proximal deep venous thrombosis (DVT) catheter-directed (CDT) and pharmacomechanical thrombolysis may be a reasonable alternative therapeutic method. Our aim was to summarize our results using these methods.
  
  
  
  Since 2009 twenty-four patients with iliofemoral DVT were treated with these endovascular procedures and with stenting at our Institution.
  
  
  
  The median age of the patients was 35.83 ± 15.9 years, the female: male ratio was approximately 2:1. The mean time between the onset of the symptoms and the procedures was eleven days. CDT alone was performed in 8 patients, thrombus aspiration in addition to CDT using AngioJet device in 16 patients; in 19 cases the procedure was completed with venous stenting. During the follow-up we performed US examinations and estimated the severity of PTS by Villalta-scale. The total recanalization-rate was more than 50%, which even improved during the follow-up. The total lysis time and the amount of used recombinant tissue plasminogen activator decreased significantly by applying the AngioJet. We did not find any severe PTS among our patients during the follow-up visits.
  
  
  
  Our data suggests that these methods can be used efficiently and safely in the treatment of acute iliofemoral DVT.
authors.affiliation: Érsebészeti Tanszék, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika 1122 Budapest, Városmajor u. 68.
authors.forename: Anikó
authors.initials: A
authors.lastname: Berencsi
authors.affiliation: Érsebészeti Tanszék, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika 1122 Budapest, Városmajor u. 68.
authors.forename: Edit
authors.initials: E
authors.lastname: Dósa
authors.affiliation: Kardiológiai Központ, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika Budapest.
authors.forename: Balázs
authors.initials: B
authors.lastname: Nemes
authors.affiliation: Kardiológiai Központ, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika Budapest.
authors.forename: Kálmán
authors.initials: K
authors.lastname: Hüttl
authors.affiliation: Érsebészeti Tanszék, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika 1122 Budapest, Városmajor u. 68.
authors.forename: Péter
authors.initials: P
authors.lastname: Legeza
authors.affiliation: Érsebészeti Tanszék, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika 1122 Budapest, Városmajor u. 68.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Oláh
authors.affiliation: Érsebészeti Tanszék, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika 1122 Budapest, Városmajor u. 68.
authors.forename: Vera
authors.initials: V
authors.lastname: Kristóf
authors.affiliation: Érsebészeti Tanszék, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika 1122 Budapest, Városmajor u. 68.
authors.forename: György
authors.initials: G
authors.lastname: Acsády
authors.affiliation: Érsebészeti Tanszék, Semmelweis Egyetem, Városmajori Szív- és Érgyógyászati Klinika 1122 Budapest, Városmajor u. 68.
authors.forename: Péter
authors.initials: P
authors.lastname: Sótonyi
mesh_terms: D002406:Catheterization, Peripheral; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D005268:Femoral Vein / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007084:Iliac Vein / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D054070:Postthrombotic Syndrome / Q000517:prevention & control; D011788:Quality of Life; D015607:Stents; D017131:Thrombectomy; D015912:Thrombolytic Therapy / Q000009:adverse effects* / Q000379:methods; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods*; D014654:Vascular Patency / Q000187:drug effects; D020246:Venous Thrombosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*
chemical_list: D005343:Fibrinolytic Agents
keywords: catheter-directed thrombolysis; iliofemoral deep venous thrombosis; lokális katéteres lysis; pharmacomechanical thrombectomy; postthrombotic syndrome; postthromboticus szindróma; proximális mélyvénás thrombosis; thrombusaspiráció; venous stenting; vénás stent