title: Numerical simulations of the effects of retinoids on pattern formation in a hydroid.
abstract: Retinoids have been shown to influence pattern formation in hydroid polyps (Hydractinia echinata) at various levels. These effects are counteracted by an inhibitor isolated from Hydra. The present study provides a theoretical attempt to elucidate the role of retinoids by computer simulations based on a simple model of pattern formation in Hydractinia. The elements of this model are morphogens of the Gierer-Meinhardt type, namely a long-range inhibitor and a short-range activator. From the calcualtions, a reducing effect of retinoids on the propagation of the inhibitor seems most probable.
authors.affiliation: Institut für Biochemie II, Im Neuenheimer Feld 328, D-6900, Heidelberg, Germany.
authors.forename: Wolf
authors.initials: W
authors.lastname: Kemmner
keywords: Cnidaria; Pattern formation; Retinoids