title: Indian Society of Neuro-Oncology consensus guidelines for the contemporary management of medulloblastoma.
abstract: BACKGROUND
  The high success rate in the management medulloblastoma achieved in the western world is not exactly mirrored in developing countries including India. Socio-demographic differences, health-care disparity, and lack in uniformity of care with resultant widespread variations in the clinical practice are some of the reasons that may partly explain this difference in outcomes. Patients with medulloblastoma require a multi-disciplinary team approach involving but not limited to neuro-radiology, neurosurgery; neuropathology, molecular biology, radiation oncology, pediatric medical oncology and rehabilitative services for optimizing outcomes.
  
  
  METHODS
  The Indian Society of Neuro-Oncology (ISNO) constituted an expert multi-disciplinary panel with adequate representation from all stakeholders to prepare national consensus guidelines for the contemporary management of medulloblastoma.
  
  
  RESULTS
  Minimum desirable, as well as preferable though optional recommendations (as appropriate), were developed and adopted for the pre-surgical work-up including neuroimaging; neurosurgical management including surgical principles, techniques, and complications; neuropathology reporting and molecular testing; contemporary risk-stratification in the molecular era; appropriate adjuvant therapy (radiotherapy and chemotherapy); and follow-up schedule in medulloblastoma.
  
  
  CONCLUSIONS
  The current document represents a broad consensus reached amongst various stakeholders within the neuro-oncology community involved in the contemporary curative-intent management of children with medulloblastoma. It provides both general as well as specific guidelines and recommendations to be adopted by physicians and health care providers across India to achieve uniformity of care, improve disease-related outcomes, and compare results between institutions within the country.
authors.affiliation: Neuro-Oncology Disease Management Group, Tata Memorial Centre, Mumbai, Maharashtra, India.
authors.forename: Tejpal
authors.initials: T
authors.lastname: Gupta
authors.affiliation: Division of Neuro-pathology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Chitra
authors.initials: C
authors.lastname: Sarkar
authors.affiliation: Department of Neuro-surgery, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
authors.forename: Vedantam
authors.initials: V
authors.lastname: Rajshekhar
authors.affiliation: Department of Neuro-surgery, Park Clinic, Kolkata, West Bengal, India.
authors.forename: Sandip
authors.initials: S
authors.lastname: Chatterjee
authors.affiliation: Neuro-Oncology Disease Management Group, Tata Memorial Centre, Mumbai, Maharashtra, India.
authors.forename: Neelam
authors.initials: N
authors.lastname: Shirsat
authors.affiliation: Department of Neuro-surgery, King Edward Memorial Hospital, Mumbai, Maharashtra, India.
authors.forename: Dattatreya
authors.initials: D
authors.lastname: Muzumdar
authors.affiliation: Division of Radio-diagnosis and Imaging, Global Hospital, Mumbai, Maharashtra, India.
authors.forename: Sona
authors.initials: S
authors.lastname: Pungavkar
authors.affiliation: Neuro-Oncology Disease Management Group, Tata Memorial Centre, Mumbai, Maharashtra, India.
authors.forename: Girish
authors.initials: G
authors.lastname: Chinnaswamy
authors.affiliation: Neuro-Oncology Disease Management Group, Tata Memorial Centre, Mumbai, Maharashtra, India.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Jalali
mesh_terms: D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000628:therapy*; D032921:Consensus; D006801:Humans; D007194:India; D008495:Medical Oncology / Q000592:standards; D008527:Medulloblastoma / Q000175:diagnosis / Q000628:therapy*; D009462:Neurology / Q000592:standards; D017410:Practice Guidelines as Topic / Q000592:standards; D012955:Societies, Medical / Q000592:standards