title: Peer Problems and Hyperactivity-Impulsivity Among Norwegian and American Children: The Role of 5-HTTLPR.
abstract: Peer problems are linked to attention deficit hyperactivity disorder (ADHD) symptoms and the serotonin system is thought to be involved in ADHD-related behavior. Hence, from a Gene × Environment perspective, the serotonin transporter 5-HTTLPR may play a moderating role. In two large community samples, the moderating role of 5-HTTLPR was examined related to more hyperactivity-impulsivity symptoms (HI symptoms) predicted by more peer problems. In Study 1, involving 642 Norwegian children, results indicated that for s-allele carriers only, caregiver-reported peer problems at age 4 predicted more parent-reported HI symptoms at age 6. In Study 2, similar results emerged involving 482 American children. Discussion focuses on differential sensitivity to the adverse effects of poor peer relations.
authors.affiliation: NTNU Social Research.|NTNU.
authors.forename: Frode
authors.initials: F
authors.lastname: Stenseng
authors.affiliation: University of California, Davis.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Li
authors.affiliation: University of California, Davis.
authors.forename: Jay
authors.initials: J
authors.lastname: Belsky
authors.affiliation: NTNU Social Research.
authors.forename: Beate W
authors.initials: BW
authors.lastname: Hygen
authors.affiliation: NTNU Social Research.
authors.forename: Vera
authors.initials: V
authors.lastname: Skalicka
authors.affiliation: NTNU.
authors.forename: Ismail C
authors.initials: IC
authors.lastname: Guzey
authors.affiliation: NTNU Social Research.|NTNU.
authors.forename: Lars
authors.initials: L
authors.lastname: Wichstrøm
mesh_terms: D002648:Child; D002652:Child Behavior / Q000502:physiology*; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000502:physiology*; D007398:Interpersonal Relations; D008297:Male; D009664:Norway; D010379:Peer Group; D011595:Psychomotor Agitation / Q000235:genetics / Q000503:physiopathology*; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics*; D014481:United States
chemical_list: C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins