title: Regional Comparison of Multiphase Computed Tomographic Angiography and Computed Tomographic Perfusion for Prediction of Tissue Fate in Ischemic Stroke.
abstract: Within different brain regions, we determine the comparative value of multiphase computed tomographic angiography (mCTA) and computed tomographic perfusion (CTP) in predicting follow-up infarction.
  
  
  
  Patients with M1-middle cerebral artery occlusions were prospectively included in this multicenter study. Regional analysis was performed for each patient within Alberta Stroke Program Early CT Score regions M2 to M6. Regional pial vessel filling was assessed on mCTA in 3 ways: (1) Washout of contrast within pial vessels; (2) Extent of maximal pial vessel enhancement compared with contralateral hemisphere; (3) Delay in maximal pial vessel enhancement compared with contralateral hemisphere. Cerebral blood flow, cerebral blood volume, and Tmax data were extracted within these Alberta Stroke Program Early CT Score regions. Twenty-four- to 36-hour magnetic resonance imaging/CT was assessed for infarct in each Alberta Stroke Program Early CT Score region (defined as >20% infarction within that region). Mixed effects logistic regression models were used to compare mCTA and CTP parameters when predicting brain infarction. Area under the receiver operating characteristics was used to assess discriminative value of statistical models.
  
  
  
  Seventy-seven patients were included. mCTA parameter washout and CTP parameter Tmax were significantly associated with follow-up infarction in all models (P<0.05). The area under the receiver operating characteristic for mCTA models ranged from 92% to 94% and was not different compared with all CTP models (P>0.05). Mean Tmax and cerebral blood volume values were significantly different between each washout score (P<0.01) and each delay score category (P<0.01). Mean Tmax, cerebral blood flow, and cerebral blood volume values were significantly different between each extent score category (P<0.05).
  
  
  
  Similar to CTP, multiphase CTA can be used to predict tissue fate regionally in acute ischemic stroke patients.
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Christopher D
authors.initials: CD
authors.lastname: d'Esterre
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Anurag
authors.initials: A
authors.lastname: Trivedi
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Pooneh
authors.initials: P
authors.lastname: Pordeli
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Mari
authors.initials: M
authors.lastname: Boesen
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Shivanand
authors.initials: S
authors.lastname: Patil
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Seong
authors.initials: S
authors.lastname: Hwan Ahn
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Mohamed
authors.initials: M
authors.lastname: Najm
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Enrico
authors.initials: E
authors.lastname: Fainardi
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Jai Jai Shiva
authors.initials: JJ
authors.lastname: Shankar
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Marta
authors.initials: M
authors.lastname: Rubiera
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Mohammed A
authors.initials: MA
authors.lastname: Almekhlafi
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Jennifer
authors.initials: J
authors.lastname: Mandzia
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Khaw
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Philip
authors.initials: P
authors.lastname: Barber
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Shelagh
authors.initials: S
authors.lastname: Coutts
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Michael D
authors.initials: MD
authors.lastname: Hill
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Demchuk
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Tolulope
authors.initials: T
authors.lastname: Sajobi
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Nils D
authors.initials: ND
authors.lastname: Forkert
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Mayank
authors.initials: M
authors.lastname: Goyal
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.).
authors.forename: Ting-Yim
authors.initials: TY
authors.lastname: Lee
authors.affiliation: From the Calgary Stroke Program, Department of Clinical Neurosciences (C.D.d'E., M.B., S.P., M.N., P.B., S.C., M.D.H., A.M.D., T.S., M.G., B.K.M.), Department of Radiology (C.D.d'E., M.D.H., N.D.F., M.G., T.-Y.L.), Department of Community Health Sciences (P.P., M.D.H., T.S.), and Hotchkiss Brain Institute (P.B., S.C., M.D.H., A.M.D., M.G.), University of Calgary, AB; Seaman Family Center, Calgary, Alberta (C.D.d'E., M.N., M.D.H., A.M.D., M.G., B.K.M.); Department of Neurology, Vancouver Island Health, Victoria, BC (A.T.); Department of Neurology, Chosun University School of Medicine, Gwang Ju, South Korea (S.H.A.); Department of Diagnostic Imaging, University Hospital, Florence, Italy (E.F.); Department of Neurology, Neuroradiology, Dalhousie University, Halifax, Nova Scotia (J.J.S.S.); Department of Neurology, Hospital Vall d'Hebron, Ps. Vall d'Hebron, Barcelona, Spain (M.R.); Department of Neurology, King Abdulaziz University, Jeddah, Saudi Arabia (M.A.A.); Department of Clinical Neurosciences, University of Western Ontario, London (J.M., A.V.K.); and Lawson Health Research Institute and Robarts Research Institute, London, ON (A.V.K., T.-Y.L.). docbijoymenon@gmail.com.
authors.forename: Bijoy K
authors.initials: BK
authors.lastname: Menon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography / Q000379:methods; D000072226:Computed Tomography Angiography / Q000379:methods; D005260:Female; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D055420:Perfusion Imaging / Q000379:methods; D011379:Prognosis; D011446:Prospective Studies; D020521:Stroke / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: infarction; logistic models; magnetic resonance imaging; stroke; tomography