title: Neurocysticercosis in a Rhesus Macaque (Macaca mulatta).
abstract: An 8-y-old, intact, male rhesus macaque (Macaca mulatta) was sedated to undergo MRI in preparation for the implantation of cranial hardware. During imaging, 9 focal lesions were noted in the brain and musculature of the head. The lesions were hyperechoic with hypoechoic rims. The animal was deemed inappropriate for neuroscience research, and euthanasia was elected. Gross examination revealed multiple round, thick-walled, fluid-filled cysts (diameter, approximately 0.5 cm) in multiple tissues: one each in the left caudal lung lobe, left masseter muscle, and the dura overlying the brain and 8 throughout the gray and white matter of the brain parenchyma. Formalin-fixed sections of cyst-containing brain were stained with hematoxylin and eosin. Microscopic examination and molecular analysis of the COX1 (COI) gene recognized the causative organism as Taenia solium at 99.04% identity.
authors.affiliation: Department of Pathobiology and University Laboratory Animal Resources, University of Pennsylvania, Philadelphia, Pennsylvania, New York.
authors.forename: Jessica M
authors.initials: JM
authors.lastname: Johnston
authors.affiliation: Department of Pathobiology and University Laboratory Animal Resources, University of Pennsylvania, Philadelphia, Pennsylvania, New York.
authors.forename: Cecilia D
authors.initials: CD
authors.lastname: Dyer
authors.affiliation: Department of Pathobiology, Wadsworth Center, Albany, New York.
authors.forename: Susan
authors.initials: S
authors.lastname: Madison-Antenucci
authors.affiliation: Department of Pathobiology, Wadsworth Center, Albany, New York.
authors.forename: Kimberly Am
authors.initials: KA
authors.lastname: Mergen
authors.affiliation: Department of Pathobiology and University Laboratory Animal Resources, University of Pennsylvania, Philadelphia, Pennsylvania, New York.
authors.forename: Christin L
authors.initials: CL
authors.lastname: Veeder
authors.affiliation: Department of Pathobiology and University Laboratory Animal Resources, University of Pennsylvania, Philadelphia, Pennsylvania, New York;, Email: abrice@upenn.edu.
authors.forename: Angela K
authors.initials: AK
authors.lastname: Brice
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D008253:Macaca mulatta; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D008992:Monkey Diseases / Q000473:pathology; D020019:Neurocysticercosis / Q000662:veterinary*; D041201:Taenia solium / Q000302:isolation & purification*