title: Outcomes of Endodontic Microsurgery Using a Microscope and Mineral Trioxide Aggregate: A Prospective Cohort Study.
abstract: BACKGROUND
  The aim of this study was to investigate the outcome of endodontic microsurgery and analyze the prognostic factors.
  
  
  METHODS
  Our prospective cohort study included 98 teeth in 81 patients. An endodontist performed all surgical procedures using endodontic microsurgical approaches. The treated teeth were recalled and examined clinically and radiographically at least 1 year after surgical treatment. The outcome was determined based on clinical and radiographic results. Radiographic healing was classified into 4 categories: complete, incomplete, uncertain, and unsatisfactory healing. An analysis of predictors was performed using multivariate logistic regression.
  
  
  RESULTS
  At recall, 74 of the 98 teeth (75.5%) were examined 12 to 30 months after surgery; 71 of the 74 teeth were analyzed clinically and radiographically, and 3 teeth had been extracted. On periapical radiographs, 55 (74.3%) of the 74 teeth showed complete healing, whereas 12 (16.2%) demonstrated incomplete healing. Together the percentage of complete and incomplete healing was 90.5% (67/74), and all 67 teeth were clinically normal. Uncertain healing was observed in 3 teeth (4.1%), one of which was symptomatic with swelling and sinus tract involvement and the other 2 were asymptomatic. The remaining 1 tooth (1.4%) showed unsatisfactory healing and was asymptomatic. The use as an abutment was found to be a negative factor associated with patient outcome (P < .05; odds ratio = 22; confidence interval, 20.47-23.53).
  
  
  CONCLUSIONS
  The combined rate of complete and incomplete healing of teeth 12 to 30 months after endodontic microsurgery was 90.5%. The use as an abutment may have a negative effect on treatment outcome.
authors.affiliation: Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology, Beijing, China.
authors.forename: Zu-Hua
authors.initials: ZH
authors.lastname: Wang
authors.affiliation: Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology, Beijing, China.
authors.forename: Ming-Ming
authors.initials: MM
authors.lastname: Zhang
authors.affiliation: Center of Stomatology, China-Japan Friendship Hospital, Beijing, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Wang
authors.affiliation: First Clinical Division, Peking University School and Hospital of Stomatology, Beijing, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology, Beijing, China; Department of Stomatology, Peking University International Hospital, Beijing, China. Electronic address: leungyuhong@sina.com.
authors.forename: Yu-Hong
authors.initials: YH
authors.lastname: Liang
mesh_terms: D000328:Adult; D017607:Aluminum Compounds / Q000627:therapeutic use*; D017610:Calcium Compounds / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008853:Microscopy / Q000379:methods; D008866:Microsurgery / Q000295:instrumentation / Q000379:methods*; D008875:Middle Aged; D010087:Oxides / Q000627:therapeutic use*; D011446:Prospective Studies; D011861:Radiography, Dental; D012390:Root Canal Therapy / Q000295:instrumentation / Q000379:methods*; D017640:Silicates / Q000627:therapeutic use*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D017640:Silicates; C086631:mineral trioxide aggregate