title: First report of vascular invasion of demodex mites with thrombi and dissemination to visceral lymph nodes in a dog.
abstract: An adult-onset generalized canine demodecosis is a life threatening form of demodecosis often seen in immunocompromised dogs. A generalized, adult-onset canine demodecosis with an unusual vascular invasion, thrombi and dissemination to peripheral, and visceral lymph nodes was diagnosed in an adult, female, American Bulldog of unknown age. Organized thrombi with intralesional mites were observed in multiple lymphatic vessels and in a section of blood vessel. Vascular invasion of mites with dissemination of mites into visceral lymph nodes, is an unusual findings not previously recorded in canine generalized demodecosis. Dissemination of mites to visceral lymph nodes through vascular channels may be part of the pathogenesis of chronic, untreated, and disseminated, adult-onset generalized canine demodecosis.
authors.affiliation: Tifton Veterinary Diagnostic and Investigational Laboratory, Department of Pathology, College of Veterinary Medicine, University of Georgia, 43 Brighton Rd, Tifton, GA 31793, USA. Electronic address: mwoldem@uga.edu.
authors.forename: Moges
authors.initials: M
authors.lastname: Woldemeskel
authors.affiliation: Tifton Veterinary Diagnostic and Investigational Laboratory, Department of Pathology, College of Veterinary Medicine, University of Georgia, 43 Brighton Rd, Tifton, GA 31793, USA.
authors.forename: Ian
authors.initials: I
authors.lastname: Hawkins
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000469:parasitology; D004285:Dogs; D005260:Female; D005845:Georgia; D008198:Lymph Nodes / Q000000981:diagnostic imaging* / Q000469:parasitology; D008924:Mite Infestations / Q000175:diagnosis / Q000469:parasitology / Q000662:veterinary*; D008925:Mites / Q000145:classification / Q000502:physiology*; D013927:Thrombosis / Q000000981:diagnostic imaging* / Q000469:parasitology
keywords: Canine; Demodex; Generalized; Lymph node; Vascular invasion