title: Tissue specific nuclear antigens in the germinal vesicle ofXenopus laevis oocytes.
abstract: A library of hybridoma cell lines has been established which produce monoclonal antibodies against antigens from the germinal vesicle ofXenopus laevis oocytes. Many of the antigens are also found in the nuclei ofXenopus embryonic cells in culture. The fate of two of these antigens during embryogenesis was traced by immunofluorescence on embryo and tadpole sections. Early in development these antigens appear to be evenly distributed in the nuclei of all cells. In later stages they gradually disappear from most embryonic structures but are strongly accumulated in the nuclei of some specific cell types and organs.
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstr. 35, D-7400, Tübingen, Germany.
authors.forename: Christine
authors.initials: C
authors.lastname: Dreyer
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstr. 35, D-7400, Tübingen, Germany.
authors.forename: Helen
authors.initials: H
authors.lastname: Singer
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstr. 35, D-7400, Tübingen, Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Hausen
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstr. 35, D-7400, Tübingen, Germany.
authors.forename: Ursula
authors.initials: U
authors.lastname: Müller
authors.affiliation: Max-Planck-Institut für Virusforschung, Spemannstr. 35, D-7400, Tübingen, Germany.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Siegel
keywords: Embryogenesis; Monoclonal antibodies; Oocyte nuclear proteins