title: Obstetrician's risk perception on the prescription of magnesium sulfate in severe preeclampsia and eclampsia: A qualitative study in Brazil.
abstract: BACKGROUND
  Magnesium sulfate (MgSO4) is the drug of choice for the prevention and control of seizures in the management of severe preeclampsia/eclampsia. Several barriers have been identified in the use of MgSO4, especially in low and middle-income settings.
  
  
  OBJECTIVE
  To describe the obstetrician's perception on possible reasons for underutilizing magnesium sulfate to treat preeclampsia/eclampsia.
  
  
  METHODS
  A qualitative clinical study, based on phenomenological reference by semi-structured interviews and open-ended discussions with obstetricians of the public healthcare system in primary care units (PCU) and referral maternity hospitals (RMH), in a southeastern Brazilian city.
  
  
  RESULTS
  Fear of drug toxicity was the major cause for not prescribing the medication in PCU. Fear was justified by insufficient technical, structural and organizational resources of healthcare facilities and by a shortage of physicians properly trained for adequate drug use.
  
  
  CONCLUSIONS
  Fear of toxicity of magnesium sulfate was the main barrier towards timely and proper drug use. Periodic skill development and training of obstetricians, along with integration of the medical team in the work environment may contribute to decrease fear, ensuring safety of drug prescription and thus possibly reducing adverse outcomes related to PE.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medical Sciences of the University of Campinas, Campinas, State of São Paulo, Brazil.
authors.forename: Fátima Aparecida
authors.initials: FA
authors.lastname: Lotufo
authors.affiliation: Department of Obstetrics and Gynecology, School of Medical Sciences of the University of Campinas, Campinas, State of São Paulo, Brazil.
authors.forename: Mary Angela
authors.identifier: http://orcid.org/0000-0002-6000-9707
authors.initials: MA
authors.lastname: Parpinelli
authors.affiliation: Sociologist and Full Professor of the Postgraduate Program on Obstetrics and Gynecology-School of Medical Sciences of the University of Campinas, Campinas, State of São Paulo, Brazil.
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Osis
authors.affiliation: Department of Obstetrics and Gynecology, School of Medical Sciences of the University of Campinas, Campinas, State of São Paulo, Brazil.
authors.forename: Fernanda Garanhani
authors.initials: FG
authors.lastname: Surita
authors.affiliation: Department of Obstetrics and Gynecology, School of Medical Sciences of the University of Campinas, Campinas, State of São Paulo, Brazil.
authors.forename: Maria Laura
authors.initials: ML
authors.lastname: Costa
authors.affiliation: Department of Obstetrics and Gynecology, School of Medical Sciences of the University of Campinas, Campinas, State of São Paulo, Brazil.
authors.forename: José Guilherme
authors.initials: JG
authors.lastname: Cecatti
mesh_terms: D000328:Adult; D001291:Attitude of Health Personnel; D001938:Brazil; D004461:Eclampsia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008278:Magnesium Sulfate / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009774:Obstetrics; D011225:Pre-Eclampsia / Q000188:drug therapy*; D011247:Pregnancy; D012306:Risk; D000078329:Workforce
chemical_list: D008278:Magnesium Sulfate