title: Sample size of the reference sample in a case-augmented study.
abstract: The case-augmented study, in which a case sample is augmented with a reference (random) sample from the source population with only covariates information known, is becoming popular in different areas of applied science such as pharmacovigilance, ecology, and econometrics. In general, the case sample is available from some source (for example, hospital database, case registry, etc.); however, the reference sample is required to be drawn from the corresponding source population. The required minimum size of the reference sample is an important issue in this regard. In this work, we address the minimum sample size calculation and discuss related issues. Copyright © 2017 John Wiley & Sons, Ltd.
authors.affiliation: Centre for Quantitative Medicine, Duke-National University of Singapore Medical School, Singapore.
authors.forename: Palash
authors.identifier: http://orcid.org/0000-0001-9605-1213
authors.initials: P
authors.lastname: Ghosh
authors.affiliation: Applied Statistics Unit, Indian Statistical Institute, Kolkata, India.
authors.forename: Anup
authors.initials: A
authors.lastname: Dewanji
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology; D006801:Humans; D017891:Pharmacoepidemiology / Q000379:methods*; D060735:Pharmacovigilance; D012107:Research Design; D018401:Sample Size
keywords: adverse drug reaction; case-augmented study; case-control data; pharmacoepidemiology; pharmacovigilance; reference sample; sample size; spontaneous reporting database