title: RETRACTED: The effects of the long non-coding RNA MALAT-1 regulated autophagy-related signaling pathway on chemotherapy resistance in diffuse large B-cell lymphoma.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
  
  This article has been retracted at the request of the Editor-in-Chief.
  
  An Expression of Concern for this article was previously published while an investigation was conducted (see related editorial: https://doi.org/10.1016/j.biopha.2022.113812). This retraction notice supersedes the Expression of Concern published earlier.
  
  Concern was raised about the reliability of the images in Figure 5B, and the Western blots shown in Figure 9A+B, which appear to contain similar repeated features, and a phenotype found in other publications, as detailed here: https://pubpeer.com/publications/81D7B72D646EC532D0DFF63338A55F; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Independent analysis confirmed these findings and identified additional suspected image duplications in Figures 5A+B and 9A+B. The journal requested the corresponding author comment on these concerns and provide the associated raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.
authors.affiliation: Department of Hematology, Lanzhou University Second Hospital, Lanzhou, 730000, China.
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Li
authors.affiliation: Department of Hematology, Lanzhou University Second Hospital, Lanzhou, 730000, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Chai
authors.affiliation: Department of Hematology, Lanzhou University Second Hospital, Lanzhou, 730000, China.
authors.forename: Xiao-Jia
authors.initials: XJ
authors.lastname: Guo
authors.affiliation: Department of Hematology, Lanzhou University Second Hospital, Lanzhou, 730000, China.
authors.forename: Song-Lin
authors.initials: SL
authors.lastname: Chu
authors.affiliation: Department of Hematology, Lanzhou University Second Hospital, Lanzhou, 730000, China. Electronic address: zhangls846@163.com.
authors.forename: Lian-Sheng
authors.initials: LS
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D045744:Cell Line, Tumor; D019008:Drug Resistance, Neoplasm; D015972:Gene Expression Regulation, Neoplastic / Q000502:physiology; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008819:Mice, Nude; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000378:metabolism; D062085:RNA, Long Noncoding / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
chemical_list: D000970:Antineoplastic Agents; C557041:MALAT1 long non-coding RNA, human; D062085:RNA, Long Noncoding
keywords: Autophagy; Chemotherapy; Diffuse large B-cell lymphoma; Long non-coding RNA MALAT-1; Resistance; Signaling pathway