title: [Event-related potential of working memory on emotional faces in children with autism spectrum disorder].
abstract: OBJECTIVE
  To investigate the characteristics of working memory ability on emotional faces and related event-related potential (ERP) in children with autism spectrum disorder (ASD).
  
  
  METHODS
  The Chinese Facial Affective Picture System was used as test material, and the event-related potential system was used to record the electroencephalographic data when 16 ASD children aged 6-12 years (ASD group) and 14 normal children matched for age (control group) were completing the facial emotion delayed match-to-sample task. The characteristics of P3b component were analyzed for both groups.
  
  
  RESULTS
  Compared with the control group, the ASD group had a significantly longer reaction time (1 527 ms vs 1 060 ms; P<0.05) and a significantly lower accuracy rate (76% vs 88%; P<0.01) in the facial emotion delayed match-to-sample task. There was a difference in the amplitude of P3b component during the encoding stage between the two groups. In the ASD group, the P3b component on the left side electrode had a higher amplitude than that on the right side electrode (P<0.05), while the control group had no such characteristics.
  
  
  CONCLUSIONS
  There is a difference in P3b component during the encoding stage between school-aged ASD children and normal children. In ASD children, working memory on emotional faces may depend more on the related neural pathway in the left hemisphere.
authors.affiliation: Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. jinyu@mail.sysu.edu.cn.
authors.forename: Cai-Juan
authors.initials: CJ
authors.lastname: Xu
authors.forename: Ling
authors.initials: L
authors.lastname: Zhang
authors.forename: Ning
authors.initials: N
authors.lastname: Pan
authors.forename: Qiong-Xi
authors.initials: QX
authors.lastname: Lin
authors.forename: Jun
authors.initials: J
authors.lastname: Ye
authors.forename: Jin
authors.initials: J
authors.lastname: Jing
authors.forename: Yu
authors.initials: Y
authors.lastname: Jin
mesh_terms: D000067877:Autism Spectrum Disorder / Q000503:physiopathology / Q000523:psychology*; D002648:Child; D004644:Emotions; D005071:Evoked Potentials; D005149:Facial Expression; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term