title: [Investigation of Lung Cancer Patients Complicated with Chronic Obstructive Pulmonary Disease in Thoracic Surgical Department].
abstract: BACKGROUND
  Lung cancer is an important complication of chronic obstructive pulmonary disease (COPD), and even significantly affects the prognosis of patients with COPD. COPD also affects the postoperative complications and recurrence in patients with lung cancer. This study aims to investigate lung cancer patients complicated with COPD in thoracic surgical department.
  
  
  METHODS
  All medical records of lung cancer patients discharged from the Department of Thoracic Surgery of People's Hospital, Peking University during January 2015 and December 2015 were reviewed, including gender, age, tobacco smoke history, harmful occupational exposure, clinic symptom, chest computed tomography (CT) scanning, postoperative pathology result report, discharged diagnosis and spirometry [All patients underwent pulmonary function test are received bronchial dilation test if the based predicted value of forced expiratory volume in one second (FEV1) <70%].
  
  
  RESULTS
  A full set of lung function test was measured in 703 lung cancer patients. Bronchial dilation test was finished in 67 patients. 62 (92.5%) patients were diagnosed as COPD. 677 cases with lung cancer were received surgery. Bronchial dilation test was measured in 42 cases. Of them 38 (92.7%) patients were diagnosed as COPD. It was found that the patients with lung cancer and COPD was more frequent in males, elders (≥65 yr), smokers, non-adenocarcinoma patients than those of patients without COPD (P<0.05). The males and the elders (≥65 yr) were more likely to suffer from COPD (OR: 2.374-2.807, 95%CI: 1.101-7.157)(P<0.05). Only 3 patients (4.3‰) were diagnosed as COPD and received standard treatment before admission. And only 5 patients (7.1‰) were diagnosed as COPD as discharged.
  
  
  CONCLUSIONS
  The routine pulmonary function as well as bronchial dilation test are helpful for screening the patients with COPD. At present, the diagnosis and treatment of lung cancer combined with COPD is a serious problem, which needs to be paid attention to by thoracic surgeons and to join hands with physicians in order to improve the diagnosis level of COPD.
authors.affiliation: Department of Respiratory and Critical Care, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Rongbao
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Department of Respiratory and Critical Care, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Xingyu
authors.initials: X
authors.lastname: Tan
authors.affiliation: Department of Respiratory and Critical Care, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Department of Respiratory and Critical Care, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Jingan
authors.initials: J
authors.lastname: Wei
authors.affiliation: Department of Respiratory and Critical Care, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Gai
authors.affiliation: Department of Respiratory and Critical Care, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Education Division, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Ziyi
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Education Division, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: Education Division, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Liyu
authors.initials: L
authors.lastname: Zhu
authors.affiliation: Education Division, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Zhongxian
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Department of Respiratory and Critical Care, People's Hospital Peking University, Beijing 100044, China.
authors.forename: Quanying
authors.initials: Q
authors.lastname: He
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D012129:Respiratory Function Tests; D012907:Smoking; D019616:Thoracic Surgical Procedures