title: Prevention of Infection in Orthopedic Prosthetic Surgery.
abstract: Total joint arthroplasty is a generally safe orthopedic procedure; however, infection is a potentially devastating complication. Multiple risk factors have been identified for development of prosthetic joint infections. Identification of patients at risk and preoperative correction of known risk factors, such as smoking, diabetes mellitus, anemia, malnutrition, and decolonization of Staphylococcus carriers, represent well-established actions to decrease the infection risk. Careful operative technique, proper draping and skin preparation, and appropriate selection and dosing of antimicrobials for perioperative prophylaxis are also very important in prevention of infection.
authors.affiliation: Department of infectious Diseases, University Hospital, 1350 Walton Way, Augusta, GA 30909, USA.
authors.forename: Ioana
authors.initials: I
authors.lastname: Chirca
authors.affiliation: Division of Infectious Diseases, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA. Electronic address: marcule@musc.edu.
authors.forename: Camelia
authors.initials: C
authors.lastname: Marculescu
mesh_terms: D019072:Antibiotic Prophylaxis; D002353:Carrier State; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D007595:Joint Prosthesis / Q000009:adverse effects / Q000382:microbiology*; D008297:Male; D019637:Orthopedic Procedures / Q000009:adverse effects*; D010003:Osteoarthritis / Q000150:complications / Q000382:microbiology / Q000517:prevention & control / Q000601:surgery; D011182:Postoperative Care; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000517:prevention & control*; D012307:Risk Factors
keywords: Infection; Orthopedic; Prophylaxis; Prosthetic joint