title: Copper-Catalyzed Selective ortho-C-H/N-H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids.
abstract: An efficient and convenient copper-catalyzed method has been developed to achieve direct ortho-C-H/N-H annulation to synthesize phenanthridinones with arynes. This method highlights an emerging strategy to transform inert C-H bonds into versatile functional groups in organic synthesis and provides a new way to synthesize phenanthridinone alkaloids efficiently.
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Ting-Yu
authors.initials: TY
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Jun-Bing
authors.initials: JB
authors.lastname: Lin
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Quan-Zhe
authors.initials: QZ
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Jun-Chen
authors.initials: JC
authors.lastname: Kang
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Jin-Long
authors.identifier: 0000-0002-1085-4566
authors.initials: JL
authors.lastname: Pan
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Si-Hua
authors.initials: SH
authors.lastname: Hou
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.affiliation: School of Chemistry and Chemical Engineering, ‡Sixth People's Hospital South Campus, and §Zhiyuan College, Shanghai Jiao Tong University , Shanghai 200240, P. R. China.
authors.forename: Shu-Yu
authors.identifier: 0000-0002-1811-4159
authors.initials: SY
authors.lastname: Zhang