title: Longterm Effectiveness of Herpes Zoster Vaccine among Patients with Autoimmune and Inflammatory Diseases.
abstract: The protection duration of herpes zoster (HZ) vaccination is unclear among patients with autoimmune (AI) diseases.
  
  
  
  Using 2006-2013 Medicare data, HZ vaccinated patients with AI were matched 1:2 to unvaccinated HZ. Incidence rates (IR) and adjusted risk ratios over time were calculated using Poisson regression.
  
  
  
  Of 59,627 vaccinated patients, crude IR increased from 0.75/100 person-years during the first year post-vaccination to 1.25 during the seventh year. Vaccinated patients had a significantly lower risk of HZ compared with the unvaccinated through 5 years.
  
  
  
  HZ vaccination was significantly protective only for about 5 years among patients with AI.
authors.affiliation: From the University of Alabama at Birmingham, Birmingham, Alabama; Oregon Health and Science University, Portland, Oregon, USA.|H. Yun, PhD, University of Alabama at Birmingham; F. Xie, MS, University of Alabama at Birmingham; J.W. Baddley, MD, MPH, University of Alabama at Birmingham; K. Winthrop, MD, MPH, Oregon Health and Science University; K.G. Saag, MD, MSc, University of Alabama at Birmingham; J.R. Curtis, MD, MS, MPH, University of Alabama at Birmingham.
authors.forename: Huifeng
authors.initials: H
authors.lastname: Yun
authors.affiliation: From the University of Alabama at Birmingham, Birmingham, Alabama; Oregon Health and Science University, Portland, Oregon, USA.|H. Yun, PhD, University of Alabama at Birmingham; F. Xie, MS, University of Alabama at Birmingham; J.W. Baddley, MD, MPH, University of Alabama at Birmingham; K. Winthrop, MD, MPH, Oregon Health and Science University; K.G. Saag, MD, MSc, University of Alabama at Birmingham; J.R. Curtis, MD, MS, MPH, University of Alabama at Birmingham.
authors.forename: Fenglong
authors.initials: F
authors.lastname: Xie
authors.affiliation: From the University of Alabama at Birmingham, Birmingham, Alabama; Oregon Health and Science University, Portland, Oregon, USA.|H. Yun, PhD, University of Alabama at Birmingham; F. Xie, MS, University of Alabama at Birmingham; J.W. Baddley, MD, MPH, University of Alabama at Birmingham; K. Winthrop, MD, MPH, Oregon Health and Science University; K.G. Saag, MD, MSc, University of Alabama at Birmingham; J.R. Curtis, MD, MS, MPH, University of Alabama at Birmingham.
authors.forename: John W
authors.initials: JW
authors.lastname: Baddley
authors.affiliation: From the University of Alabama at Birmingham, Birmingham, Alabama; Oregon Health and Science University, Portland, Oregon, USA.|H. Yun, PhD, University of Alabama at Birmingham; F. Xie, MS, University of Alabama at Birmingham; J.W. Baddley, MD, MPH, University of Alabama at Birmingham; K. Winthrop, MD, MPH, Oregon Health and Science University; K.G. Saag, MD, MSc, University of Alabama at Birmingham; J.R. Curtis, MD, MS, MPH, University of Alabama at Birmingham.
authors.forename: Kevin
authors.initials: K
authors.lastname: Winthrop
authors.affiliation: From the University of Alabama at Birmingham, Birmingham, Alabama; Oregon Health and Science University, Portland, Oregon, USA.|H. Yun, PhD, University of Alabama at Birmingham; F. Xie, MS, University of Alabama at Birmingham; J.W. Baddley, MD, MPH, University of Alabama at Birmingham; K. Winthrop, MD, MPH, Oregon Health and Science University; K.G. Saag, MD, MSc, University of Alabama at Birmingham; J.R. Curtis, MD, MS, MPH, University of Alabama at Birmingham.
authors.forename: Kenneth G
authors.initials: KG
authors.lastname: Saag
authors.affiliation: From the University of Alabama at Birmingham, Birmingham, Alabama; Oregon Health and Science University, Portland, Oregon, USA. jcurtis@uab.edu.|H. Yun, PhD, University of Alabama at Birmingham; F. Xie, MS, University of Alabama at Birmingham; J.W. Baddley, MD, MPH, University of Alabama at Birmingham; K. Winthrop, MD, MPH, Oregon Health and Science University; K.G. Saag, MD, MSc, University of Alabama at Birmingham; J.R. Curtis, MD, MS, MPH, University of Alabama at Birmingham. jcurtis@uab.edu.
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Curtis
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001327:Autoimmune Diseases; D005260:Female; D006562:Herpes Zoster / Q000453:epidemiology / Q000517:prevention & control*; D053061:Herpes Zoster Vaccine; D006801:Humans; D015994:Incidence; D007249:Inflammation; D008297:Male; D006278:Medicare; D012189:Retrospective Studies; D016896:Treatment Outcome; D014481:United States; D014611:Vaccination
chemical_list: D053061:Herpes Zoster Vaccine
keywords: AUTOIMMUNE DISEASES; HERPES ZOSTER; INFECTION; VACCINATION