title: Live Cell Therapy as Potential Risk Factor for Q Fever.
abstract: During an outbreak of Q fever in Germany, we identified an infected sheep flock from which animals were routinely used as a source for life cell therapy (LCT), the injection of fetal cells or cell extracts from sheep into humans. Q fever developed in 7 LCT recipients from Canada, Germany, and the United States.
authors.forename: Maja
authors.initials: M
authors.lastname: George
authors.forename: Andreas
authors.initials: A
authors.lastname: Reich
authors.forename: Klaus
authors.initials: K
authors.lastname: Cussler
authors.forename: Herrmann
authors.initials: H
authors.lastname: Jehl
authors.forename: Florian
authors.initials: F
authors.lastname: Burckhardt
mesh_terms: D000328:Adult; D000818:Animals; D064987:Cell- and Tissue-Based Therapy / Q000009:adverse effects*; D016997:Coxiella burnetii / Q000276:immunology; D004196:Disease Outbreaks; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011778:Q Fever / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D012307:Risk Factors; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology; D015047:Zoonoses
keywords: Canada; Coxiella burnetii; Germany; Q fever; bacteria; fetal tissue; inhalation exposure; intramuscular injection; live cell therapy; occupational exposure; outbreaks; risk factor; sheep; zoonoses