title: Residue analysis and persistence evaluation of fipronil and its metabolites in cotton using high-performance liquid chromatography-tandem mass spectrometry.
abstract: A simple residue analytical method based on the QuEChERS approach and high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) detection was developed for the analysis of fipronil and its three metabolites in cottonseed, cotton plant and soil. The average recoveries of four test compounds from all three matrices were 78.6-108.9% at the level of 0.005 to 0.5 mg/kg, with an RSD in the range of 0.6 to 13.7%. The limit of quantification (LOQ) of the four test compounds ranged from 0.005 to 0.01 mg/kg. The results of the residual dynamics experiments showed that fipronil dissipated rapidly in cotton plants and soil and that oxidation and photolysis were the main degradation pathways. Moreover, the bi-exponential models demonstrated a good fit of the measured data for fipronil in cotton plants and soil, with R2 in the range of 0.8989 to 0.9989. Furthermore, a total of 40 samples of cottonseed from Shandong Province were analyzed, and all of the samples were free from the four test compound residues.
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.
authors.forename: Xiaohu
authors.initials: X
authors.lastname: Wu
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.|Solid Waste and Chemicals Management Center, Ministry of Environmental Protection, Yuhuinanlu No.1, Chaoyang District, Beijing, Beijing, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yu
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.
authors.forename: Fengshou
authors.initials: F
authors.lastname: Dong
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.
authors.forename: Xingang
authors.initials: X
authors.lastname: Liu
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.
authors.forename: Pengqiang
authors.initials: P
authors.lastname: Du
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.
authors.forename: Dongmei
authors.initials: D
authors.lastname: Wei
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, State Key Laboratory for Biolog of Plant Diseases and Insect Pests, Haidian District, Beijing, China.
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003368:Gossypium / Q000737:chemistry*; D007306:Insecticides / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D011720:Pyrazoles / Q000032:analysis*; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D007306:Insecticides; D010573:Pesticide Residues; D011720:Pyrazoles; C082360:fipronil