title: A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications.
abstract: Here, we developed a general strategy for synthesizing homogeneous HA conjugates, and generated homogeneous HA-pNP, HA-biotin, and HA-oroxylin conjugates to investigate the relationships between HA chain length and its diverse biological functions.
authors.affiliation: National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
authors.forename: Xuan
authors.initials: X
authors.lastname: Fu
authors.affiliation: National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Shang
authors.affiliation: Department of Chemistry and Center of Diagnostics & Therapeutics, Georgia State University, 50 Decatur St SE, Atlanta, GA 30303, USA. pwang11@gsu.edu.
authors.forename: Shuaishuai
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Chemistry and Center of Diagnostics & Therapeutics, Georgia State University, 50 Decatur St SE, Atlanta, GA 30303, USA. pwang11@gsu.edu.
authors.forename: Yunpeng
authors.initials: Y
authors.lastname: Liu
authors.affiliation: National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
authors.forename: Jingyao
authors.initials: J
authors.lastname: Qu
authors.affiliation: Department of Chemistry, University of California, One Shields Avenue, Davis, CA 95616, USA.
authors.forename: Xi
authors.identifier: http://orcid.org/0000-0002-3160-614X
authors.initials: X
authors.lastname: Chen
authors.affiliation: National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn and Department of Chemistry and Center of Diagnostics & Therapeutics, Georgia State University, 50 Decatur St SE, Atlanta, GA 30303, USA. pwang11@gsu.edu.
authors.forename: Peng George
authors.initials: PG
authors.lastname: Wang
authors.affiliation: National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Glycochemistry and Glycobiology, Shandong University, Jinan, Shandong 250100, People's Republic of China. fangjunqiang@sdu.edu.cn.
authors.forename: Junqiang
authors.identifier: http://orcid.org/0000-0002-3973-1463
authors.initials: J
authors.lastname: Fang
mesh_terms: D001710:Biotin / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry; D006820:Hyaluronic Acid / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D005419:Flavonoids; C080669:5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one; D001710:Biotin; D006820:Hyaluronic Acid