title: Periocular necrotizing fasciitis in an infant.
abstract: Periocular necrotizing fasciitis developed in a 12-month-old boy with swelling of both eyes and redness and a discharge from the left eye approximately 36 hours after blunt trauma. Computed tomography revealed preseptal and soft-tissue edema on the left side, but no signs of orbital involvement, orbital fractures, or drainable abscess in the anterior left lower eyelid. The inflammatory signs worsened over the next day, and there was purulent discharge from the left lower eyelid and an abscess and necrosis of the lower eyelid skin. He did well following surgical debridement and treatment with intravenous antibiotics. His course highlights the difficulty in diagnosing necrotizing fasciitis and the necessity for prompt surgical debridement and empirical broad-spectrum antibiotic therapy.
authors.affiliation: Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA. Electronic address: proia001@mc.duke.edu.
authors.forename: Alan D
authors.initials: AD
authors.lastname: Proia
mesh_terms: D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003646:Debridement / Q000379:methods*; D015818:Eye Infections, Bacterial / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D005143:Eyelids / Q000382:microbiology* / Q000473:pathology; D019115:Fasciitis, Necrotizing / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents
keywords: Streptococcus pyogenes; cellulitis; eyelid; fascia; necrotizing fasciitis; periocular