title: 13C-Decoupled J-Coupling Spectroscopy Using Two-Dimensional Nuclear Magnetic Resonance at Zero-Field.
abstract: We present a two-dimensional method for obtaining13C-decoupled,1H-coupled nuclear magnetic resonance (NMR) spectra in zero magnetic field using coherent spin-decoupling. The result is a spectrum determined only by the proton-proton J-coupling network. Detection of NMR signals in zero magnetic field requires at least two different nuclear spin species, but the proton J-spectrum is independent of isotopomer, thus potentially simplifying spectra and thereby improving the analytical capabilities of zero-field NMR. The protocol does not rely on a difference in Larmor frequency between the coupled nuclei, allowing for the direct determination of J-coupling constants between chemically equivalent spins. We obtain the13C-decoupled zero-field spectrum of [1-13C]-propionic acid and identify conserved quantum numbers governing the appearance of cross peaks in the two-dimensional spectrum.
authors.affiliation: Department of Chemistry, University of California at Berkeley , Berkeley, California 94720-3220, United States.
authors.forename: Tobias F
authors.identifier: http://orcid.org/0000-0002-0564-4804
authors.initials: TF
authors.lastname: Sjolander
authors.affiliation: Department of Physics, University of California at Berkeley , Berkeley, California 94720-7300, United States.|Magnetic Resonance Research Centre, Department of Chemical Engineering and Biotechnology, University of Cambridge , Pembroke Street, Cambridge CB2 3RA, U.K.
authors.forename: Michael C D
authors.initials: MC
authors.lastname: Tayler
authors.affiliation: Department of Chemistry, University of California at Berkeley , Berkeley, California 94720-3220, United States.|Institute for Technical and Macromolecular Chemistry, RWTH Aachen University , 52062 Aachen, Germany.
authors.forename: Arne
authors.initials: A
authors.lastname: Kentner
authors.affiliation: Department of Physics, University of California at Berkeley , Berkeley, California 94720-7300, United States.|Helmholtz Institute Mainz, Johannes Gutenberg University , 55099 Mainz, Germany.|Materials Science Division, Lawrence Berkeley National Laboratory , Berkeley, California 94720-3220, United States.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Budker
authors.affiliation: Department of Chemistry, University of California at Berkeley , Berkeley, California 94720-3220, United States.|Materials Science Division, Lawrence Berkeley National Laboratory , Berkeley, California 94720-3220, United States.
authors.forename: Alexander
authors.initials: A
authors.lastname: Pines