title: Aptamer-based sandwich-type biosensors.
abstract: Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detection sensitivity. The sandwich-type assays can be developed by utilizing a pair of receptors, which bind to the different sites of the same target. In this mini-review paper, the sandwich-type biosensors using either pairs of aptamers or aptamer-antibody pairs are reviewed in terms of its targets and platforms, the schematic designs, and their analytical performance.
authors.affiliation: Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-Gu, Seoul, 136-713 Republic of Korea.
authors.forename: Ho Bin
authors.initials: HB
authors.lastname: Seo
authors.affiliation: Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-Gu, Seoul, 136-713 Republic of Korea.
authors.forename: Man Bock
authors.initials: MB
authors.lastname: Gu
keywords: A pair of aptamer; Aptamer-antibody complex; Aptasensor; Sandwich-type aptasensor; Sandwich-type biosensors