title: [Relationship Between Blood Serum Galectin and Renal Dysfunction in ST Elevation Myocardial Infarction].
abstract: OBJECTIVE
  to assess value for inhospital and 1 year prognosis of unfavorable course of ST-elevation myocardial infarction (STEMI) of blood serum galectin and markers of renal dysfunction (RD).
  
  
  METHODS
  Standard laboratory and instrumental examination, calculation of glomerular filtration rate using MDRD formula and by cystatin C level, determination of galectin in blood serum were carried out in 128 patients with STEMI. According to GFR by cystatin C level on day 12 of STEMI patients were divided into 2 groups - with normal renal function (GFR more or equal 60 ml/min/1.73 m2, n=47) and with RD (GFR <60 ml/min/1.73 2, n=81).
  
  
  CONCLUSIONS
  In patients with STEMI presence of RD (lowering of GFR by cystatin C, by blood serum creatinine <60 ml/min/1.73 2, creatinine clearance <60 ml/min), and elevation of galectin concentration >17.8 hg/ml on day 12 of STEMI were independent predictors of unfavorable 1 year prognosis. Elevation of galectin level directly correlated with presence of early postinfarction angina.
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: V N
authors.initials: VN
authors.lastname: Karetnikova
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Osokina
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: M V
authors.initials: MV
authors.lastname: Evseeva
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Gruzdeva
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: M V
authors.initials: MV
authors.lastname: Zykov
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Kalaeva
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Kashtalap
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: K S
authors.initials: KS
authors.lastname: Shafranskaya
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: O N
authors.initials: ON
authors.lastname: Khryachkova
authors.affiliation: 1Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia; 2Kemerovo State Medical Academy, Kemerovo, Russia.
authors.forename: O L
authors.initials: OL
authors.lastname: Barbarash
mesh_terms: D000368:Aged; D003404:Creatinine; D055316:Cystatin C; D005260:Female; D037161:Galectins / Q000097:blood*; D005919:Glomerular Filtration Rate; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D000072657:ST Elevation Myocardial Infarction / Q000097:blood / Q000503:physiopathology
chemical_list: D055316:Cystatin C; D037161:Galectins; D003404:Creatinine