title: Tp-e interval and Tp-e/QT ratio in patients with Human Immunodeficiency Virus.
abstract: Human Immunodeficiency Virus (HIV) infection and AIDS are known to cause cardiovascular diseases such as premature coronary artery disease, cardiomyopathy, and arrhythmias. Recently, Tp-e interval and Tp-e/QT ratio has been shown as a novel marker of ventricular repolarization. We aimed to evaluate the ventricular repolarization using Tp-e interval and Tp-e/QT ratio in patients with Human Immunodeficiency Virus (HIV) infection. Totally 48 patients with HIV and 60 control subjects were enrolled to the study. Tp-e interval, Tp-e/QT and Tp-e/QTc ratio were measured from the 12-lead electrocardiogram. Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio were significantly higher in patients with HIV than control subjects (all p<0.01). In correlation analysis, there were positive correlation between Tp-e interval and disease duration (r=0.298, p=0.048). and inverse correlation between Tp-e interval and CD4 count(r=-0.303, p=0.036). Our study showed that Tp-e interval, Tp-e/QT and Tp-e/QTc ratios were increased in patients with HIV than control subjects.
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Sefa
authors.initials: S
authors.lastname: Ünal
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey. Electronic address: cagriyayla@gmail.com.
authors.forename: Çağrı
authors.initials: Ç
authors.lastname: Yayla
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Açar
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Ahmet G
authors.initials: AG
authors.lastname: Ertem
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Mehmet K
authors.initials: MK
authors.lastname: Akboğa
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Gökaslan
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Mehmet A
authors.initials: MA
authors.lastname: Erdöl
authors.affiliation: Ankara Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
authors.forename: Meliha Ç
authors.initials: MÇ
authors.lastname: Sönmezer
authors.affiliation: Ankara Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Kaya Kiliç
authors.affiliation: Ankara Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
authors.forename: Çiğdem
authors.initials: Ç
authors.lastname: Ataman Hatipoğlu
authors.affiliation: Ankara Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
authors.forename: Necla
authors.initials: N
authors.lastname: Tulek
authors.affiliation: Ankara Education and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
authors.forename: Fatma S
authors.initials: FS
authors.lastname: Erdinç
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Aydoğdu
authors.affiliation: Türkiye Yüksek Ihtisas Education and Research Hospital, Department of Cardiology, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temizhan
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000473:pathology*; D003430:Cross-Sectional Studies; D004562:Electrocardiography; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006329:Heart Conduction System / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged
keywords: Human Immunodeficiency Virus; Tp–e interval; Tp–e/QT ratio