title: Sex differences in gout characteristics: tailoring care for women and men.
abstract: To characterize the differences between women and men with gout.
  
  
  
  We analyzed a US national cohort of gout patients cared for by rheumatologists.
  
  
  
  Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).
  
  
  
  The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.
authors.affiliation: Department of Medicine and Orthopedics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. leslie.harrold@umassmed.edu.
authors.forename: Leslie R
authors.initials: LR
authors.lastname: Harrold
authors.affiliation: Corrona, LLC, Southborough, MA, USA.|Department of Epidemiology, UT MD Anderson Cancer Center, Houston, TX, USA.
authors.forename: Carol J
authors.initials: CJ
authors.lastname: Etzel
authors.affiliation: Hospital for Special Surgery-Weill Medical College of Cornell University, New York, NY, USA.
authors.forename: Allan
authors.initials: A
authors.lastname: Gibofsky
authors.affiliation: Albany Medical College and The Center for Rheumatology, Albany, NY, USA.
authors.forename: Joel M
authors.initials: JM
authors.lastname: Kremer
authors.affiliation: NYU School of Medicine, New York, NY, USA.
authors.forename: Michael H
authors.initials: MH
authors.lastname: Pillinger
authors.affiliation: University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Kenneth G
authors.initials: KG
authors.lastname: Saag
authors.affiliation: Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
authors.forename: Naomi
authors.initials: N
authors.lastname: Schlesinger
authors.affiliation: VA Medical Center, UCSD, San Diego, CA, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Terkeltaub
authors.affiliation: Corrona, LLC, Southborough, MA, USA.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Cox
authors.affiliation: Corrona, LLC, Southborough, MA, USA.|NYU School of Medicine, New York, NY, USA.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Greenberg
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000178:diet therapy / Q000188:drug therapy / Q000453:epidemiology; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D006073:Gout / Q000178:diet therapy* / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy / Q000188:drug therapy / Q000453:epidemiology; D057285:Precision Medicine / Q000379:methods*; D011446:Prospective Studies; D012727:Sex Characteristics
chemical_list: D004232:Diuretics
keywords: Comorbidity; Gender; Gout; Quality of Care