title: Dual-Physical Cross-Linked Tough and Photoluminescent Hydrogels with Good Biocompatibility and Antibacterial Activity.
abstract: Development of novel photoluminescent hydrogels with toughness, biocompatibility, and antibiosis is important for the applications in biomedical field. Herein, novel tough photoluminescent lanthanide (Ln)-alginate/poly(vinyl alcohol) (PVA) hydrogels with the properties of biocompatibility and antibiosis have been facilely synthesized by introducing hydrogen bonds and coordination bonds into the interpenetrating networks of Na-alginate and PVA, via approaches of frozen-thawing and ion-exchanging. The resultant hydrogels exhibit high mechanical strength (0.6 MPa tensile strength, 5.0 tensile strain, 6.0 MPa compressive strength, and 900 kJ m-3energy dissipation under 400% stretch), good photoluminescence as well as biocompatibility and antibacterial activity. The design strategy provides a new avenue for the fabrication of multifunctional photoluminescent hydrogels based on biocompatible polymers.
authors.affiliation: School of Science, MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter and Department of Chemistry, Xi'an Jiaotong University, Xi'an, 710049, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Hu
authors.affiliation: School of Science, MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter and Department of Chemistry, Xi'an Jiaotong University, Xi'an, 710049, China.
authors.forename: Mei Xiang
authors.initials: MX
authors.lastname: Wang
authors.affiliation: School of Science, MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter and Department of Chemistry, Xi'an Jiaotong University, Xi'an, 710049, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Sun
authors.affiliation: School of Science, MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter and Department of Chemistry, Xi'an Jiaotong University, Xi'an, 710049, China.|State Key Laboratory for Strength and Vibration of Mechanical Structures, International Center for Applied Mechanics and School of Aerospace, Xi'an Jiaotong University, Xi'an, 710049, China.
authors.forename: Jian Hai
authors.initials: JH
authors.lastname: Yang
authors.affiliation: Laboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, Nagyváradtér 4, H-1084, Budapest, Hungary.
authors.forename: Miklós
authors.initials: M
authors.lastname: Zrínyi
authors.affiliation: School of Science, MOE Key Laboratory for Non-Equilibrium Synthesis and Modulation of Condensed Matter and Department of Chemistry, Xi'an Jiaotong University, Xi'an, 710049, China.|State Key Laboratory for Strength and Vibration of Mechanical Structures, International Center for Applied Mechanics and School of Aerospace, Xi'an Jiaotong University, Xi'an, 710049, China.
authors.forename: Yong Mei
authors.initials: YM
authors.lastname: Chen
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology; D019245:Compressive Strength; D020100:Hydrogels / Q000737:chemistry* / Q000494:pharmacology*; D013718:Tensile Strength
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D020100:Hydrogels
keywords: antibacterial activity; biocompatibility; hydrogels; photoluminescence; toughness