title: The relationship of alcohol consumption with left ventricular mass in people 35 years old or older in rural areas of Western China.
abstract: The aim of this study was to investigate the association between alcohol intake and left ventricular mass (LVM) independent of the effects of blood pressure and other factors in rural areas of Western China. The present study included 1007 subjects (487 men and 520 women) aged ≥35 years from the Tongan district, Chongqing, China. The quantity and frequency of alcohol consumption were estimated from a validated questionnaire. Echocardiography was used to assess left ventricular dimensions. Drinkers was associated with higher LVM compared with nondrinkers (β = 6.9, 95% confidence interval: 1.3-12.5, P = .015). A dose-dependent higher LVM across increasing alcohol consumption was observed (P < .05). LVM was significantly correlated with regular drinking (β = 10.0, 95% confidence interval: 3.6-16.4). In subjects with hypertension, quantity of alcohol consumption (P for interaction = .013) and frequency of alcohol consumption (P for interaction = .025) were strongly associated with higher LVM when stratified by blood pressure. However, interactions linked to age, body mass index, and gender were found to be no significant difference. These results indicate that both quantity and frequency of alcohol consumption are independent predictors of LVM in rural areas of Western China. The effects of alcohol consumption on LVM are enhanced among subjects with hypertension.
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.
authors.forename: Yunjing
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Feng
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.
authors.forename: Panpan
authors.initials: P
authors.lastname: Feng
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Gu
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China. Electronic address: leihan@cqmu.edu.cn.
authors.forename: Han
authors.initials: H
authors.lastname: Lei
mesh_terms: D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000453:epidemiology; D001795:Blood Pressure Determination; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000000981:diagnostic imaging; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D012307:Risk Factors; D012423:Rural Health / Q000706:statistics & numerical data*; D012424:Rural Population / Q000706:statistics & numerical data
keywords: Alcohol intake; hypertension