title: Automated glycan assembly of branched β-(1,3)-glucans to identify antibody epitopes.
abstract: β-(1,3)-Glucans exhibit immunomodulatory and anti-tumor effects. Since the isolation of pure β-(1,3)-glucan oligosaccharides from natural sources is complicated, especially when certain branching patterns are desired, chemical synthesis is frequently the only means of accessing these molecules. We report the iterative automated glycan assembly (AGA) of conjugation-ready linear and branched β-(1,3)-glucan oligosaccharides.
authors.affiliation: Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany. seeberger@mpikg.mpg.de and Department of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 22, 14195, Berlin, Germany.
authors.forename: M W
authors.initials: MW
authors.lastname: Weishaupt
authors.affiliation: Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany. seeberger@mpikg.mpg.de and Department of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 22, 14195, Berlin, Germany.
authors.forename: H S
authors.identifier: http://orcid.org/0000-0003-2326-7923
authors.initials: HS
authors.lastname: Hahm
authors.affiliation: Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany. seeberger@mpikg.mpg.de and Department of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 22, 14195, Berlin, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Geissner
authors.affiliation: Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany. seeberger@mpikg.mpg.de and Department of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 22, 14195, Berlin, Germany.
authors.forename: P H
authors.identifier: http://orcid.org/0000-0003-3394-8466
authors.initials: PH
authors.lastname: Seeberger