title: Ecdysteroids induce morphological changes in continuous cell lines of Lepidoptera.
abstract: In the continuous cell lines of the LepidopteraTrichoplusia ni (TN-368) andSpodoptera littoralis (HPB-SL-26), ecdysone and 20-hydroxyecdysone cause a series of morphological changes: some cells aggregate, elongate and extend long thin processes. The extent and rapidity of changes are dose dependent, 20-hydroxy-ecdysone being much more active then ecdysone. The continuous cell lines ofS. littoralis (UIV-SL-573) andS. frugiperda (IPLB-SF-21) were much less responsive to the presence of the ecdysteroids.
authors.affiliation: Department of Plant Geneties, The Weizmann Institute of Science, 76100, Rehovot, Israel.|Department of Biological Services, The Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Naomi
authors.initials: N
authors.lastname: Kislev
authors.affiliation: Department of Zoology, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Israel
authors.initials: I
authors.lastname: Segal
authors.affiliation: Department of Plant Geneties, The Weizmann Institute of Science, 76100, Rehovot, Israel.
authors.forename: Marvin
authors.initials: M
authors.lastname: Edelman
keywords: Ecdysteroids; Lepidoptera cell lines; Morphological changes