title: Navigating the Chiral Pool in the Total Synthesis of Complex Terpene Natural Products.
abstract: The pool of abundant chiral terpene building blocks (i.e., "chiral pool terpenes") has long served as a starting point for the chemical synthesis of complex natural products, including many terpenes themselves. As inexpensive and versatile starting materials, such compounds continue to influence modern synthetic chemistry. This review highlights 21st century terpene total syntheses which themselves use small, terpene-derived materials as building blocks. An outlook to the future of research in this area is highlighted as well.
authors.affiliation: Department of Chemistry, University of California, Berkeley , Berkeley, California 94720, United States.
authors.forename: Zachary G
authors.initials: ZG
authors.lastname: Brill
authors.affiliation: Department of Chemistry, University of California, Berkeley , Berkeley, California 94720, United States.
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Condakes
authors.affiliation: Department of Chemistry, University of California, Berkeley , Berkeley, California 94720, United States.
authors.forename: Chi P
authors.initials: CP
authors.lastname: Ting
authors.affiliation: Department of Chemistry, University of California, Berkeley , Berkeley, California 94720, United States.
authors.forename: Thomas J
authors.identifier: http://orcid.org/0000-0001-5823-692X
authors.initials: TJ
authors.lastname: Maimone
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001688:Biological Products; D013729:Terpenes