title: Renal Replacement Therapy in Acute Kidney Injury: Controversies and Consensus.
abstract: Acute kidney injury (AKI) is a common complication among critically ill patents, and 5% of intensive care unit (ICU) patients require initiation of renal replacement therapy (RRT). In recent years, clinical trials have provided evidence-based guidance for some important aspects of RRT management in patients with AKI, such as dialysis dosing and approaches to anticoagulation in patients undergoing continuous RRT. However, there remain many areas of uncertainty, and delivery of RRT in the ICU requires clinical judgment, flexibility, and an understanding of dialysis principles. This article reviews the components of RRT prescription and provides an update on best practices.
authors.affiliation: Division of Nephrology, Department of Medicine, University of Michigan, 1500 East Medical Center Drive, SPC 5364, Ann Arbor, MI 48109-5364, USA. Electronic address: mheung@umich.edu.
authors.forename: Michael
authors.initials: M
authors.lastname: Heung
authors.affiliation: Division of Nephrology, Department of Medicine, University of Michigan, 1500 East Medical Center Drive, SPC 5364, Ann Arbor, MI 48109-5364, USA.
authors.forename: Lenar
authors.initials: L
authors.lastname: Yessayan
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy*; D003422:Critical Care / Q000379:methods; D003956:Dialysis / Q000379:methods; D006801:Humans; D017410:Practice Guidelines as Topic; D017582:Renal Replacement Therapy / Q000379:methods
keywords: Acute kidney injury; Continuous renal replacement therapy; Dialysis