title: Chemical Composition and Antibacterial Activity of Iranian Lavandula × hybrida.
abstract: Lavandin (Lavandula × hybrida) is an evergreen shrub and cultivated worldwide for its essential oil which possesses various biological activities. In this study, the essential oils were isolated from the leaves of ten lavandin populations in western Iran. The hydrodistilled essential oils were analyzed by GC-FID/MS. Results indicated significant differences (P ≤ 0.05) among the various populations for the main essential oil constituents. The major components from different populations were 1,8-cineole (31.64 - 47.94%), borneol (17.11 - 26.14%), and camphor (8.41 - 12.68%). In vitro antibacterial activity was evaluated against S. agalactiae, S. aureus, E. coli, and K. pneumoniae. The inhibition zones were in the range of 09.36 mm for S. aureus to 23.30 mm for E. coli. Results indicated that there was a significant correlation between essential oil composition and level of antibacterial efficacy expressed as inhibition zones.
authors.affiliation: Young Researchers and Elite Club, Borujerd Branch, Islamic Azad University, Borujerd, Iran.
authors.forename: Iman
authors.initials: I
authors.lastname: Bajalan
authors.affiliation: Young Researchers and Elite Club, Borujerd Branch, Islamic Azad University, Borujerd, Iran.
authors.forename: Razieh
authors.initials: R
authors.lastname: Rouzbahani
authors.affiliation: Department of Medicinal Plants, Shahrekord Branch, Islamic Azad University, P.O. Box 166, Shahrekord, Iran.|Medicinal Plants ProGram, College of Natural Sciences, Massachusetts University, Amherst, MA, 01003, USA.
authors.forename: Abdollah Ghasemi
authors.initials: AG
authors.lastname: Pirbalouti
authors.affiliation: School of Pharmacy, University of Camerino, Camerino, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Maggi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D007492:Iran; D027523:Lavandula / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile; D010938:Plant Oils
keywords: 1,8-Cineole; Biological activity; Essential oil; Lavandin