title: MR imaging of intestinal angioedema related to angiotensin-converting enzyme inhibitors: Report of three cases and review of literature.
abstract: Angioedema is a condition in which an increase in vascular permeability leads to the swelling of body tissues. There are both hereditary and acquired forms of the disease, with the latter often associated with the administration of angiotensin-converting enzyme inhibitor medication. Involvement of the intestinal tract is a rare manifestation of angioedema, and can present with abdominal pain, nausea, and vomiting. It is critical for radiologists to be aware of this entity, as they may have the only opportunity to make the diagnosis. We present three cases of intestinal angioedema diagnosed on MRI with discussion of the imaging findings.
authors.affiliation: Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair St., Suite 800, Chicago, IL 60611, United States.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Savino
authors.affiliation: Department of Radiology, Emory University School of Medicine, 1364 Clifton Rd. NE, Atlanta, GA 30322, United States.
authors.forename: Pardeep K
authors.initials: PK
authors.lastname: Mittal
authors.affiliation: Department of Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair St., Suite 800, Chicago, IL 60611, United States. Electronic address: fmiller@northwestern.edu.
authors.forename: Frank H
authors.initials: FH
authors.lastname: Miller
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D000328:Adult; D000368:Aged; D000799:Angioedema / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D001364:Awareness; D002983:Clinical Competence; D005260:Female; D006801:Humans; D007422:Intestines / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D000072177:Radiologists
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors
keywords: ACE-inhibitors; Angioedema; Bowel; Gastrointestinal; MRI; Submucosal