title: [Relation of red cell distribution width and mean platelet volume with the severity of preeclampsia].
abstract: BACKGROUND
  It has been established a strong association between the red cell distribution width (RDW) and mean platelet volume (MPV) with hypertension in non-pregnant patients. However, few studies have been performed in patients with preeclampsia, yielding inconsistent results. Our aim is to evaluate the relationship between RDW and MPV with the severity of preeclampsia.
  
  
  METHODS
  Analytic cross-sectional study. We include 64 patients with preeclampsia (26 mild, 38 severe) and 70 patients with normotensive pregnancy. Clinical data, sociodemographic characteristics and laboratory measures, including RDW and MPV, were recorded for each patient.
  
  
  RESULTS
  Hemoglobin and platelet count measures were similar between groups. Preeclamptic patients had levels of RDW (14.7 ± 1.4 vs. 13.4 ± 0.7, p = 0.0001) and MPV (11.8 ± 2.4 vs. 11.0 ± 1.4, p = 0.03) more elevated than control group. Moreover, severe preeclamptic subgroup had more elevated levels of RDW (15.0 ± 1.6 vs. 14.0 ± 0.6, p = 0.001) and MPV (12.7 ± 2.8 vs. 10.8 ± 1.8, p = 0.01) in comparison with mild preeclamptic patients.
  
  
  CONCLUSIONS
  We demonstrate that RDW and MPV are accessible and inexpensive measures associated with the severity of preeclampsia.
authors.affiliation: Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Aguascalientes, México. drrosascabral@gmail.com.
authors.forename: Jesús Antonio
authors.initials: JA
authors.lastname: Viana-Rojas
authors.forename: Alejandro
authors.initials: A
authors.lastname: Rosas-Cabral
authors.forename: Jorge
authors.initials: J
authors.lastname: Prieto-Macías
authors.forename: Ma Carmen
authors.initials: MC
authors.lastname: Terrones-Saldívar
authors.forename: Patricia
authors.initials: P
authors.lastname: Arcos-Noguez
authors.forename: Julieta
authors.initials: J
authors.lastname: Bermúdez-Gómez
authors.forename: Lidia Estephanie
authors.initials: LE
authors.lastname: Martínez-Padilla
authors.forename: Darío Alejandro
authors.initials: DA
authors.lastname: Sandoval-Valdez
authors.forename: Flavio
authors.initials: F
authors.lastname: Hernández-González
authors.forename: Leopoldo César
authors.initials: LC
authors.lastname: Serrano-Díaz
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D063847:Mean Platelet Volume; D011225:Pre-Eclampsia / Q000097:blood* / Q000175:diagnosis*; D011247:Pregnancy; D012720:Severity of Illness Index
keywords: Blood platelets; Pre-eclampsia; Pregnancy complications