title: Predictive factors for pregnancy outcome following controlled ovarian stimulation and intrauterine insemination.
abstract: OBJECTIVE
  To establish predictive factors for positive pregnancy outcome in cases of controlled ovarian stimulation and intrauterine insemination.
  
  
  METHODS
  The retrospective study was conducted at Kanuni Sultan Suleyman Training and Research Hospital and comprised subjects having undergone ovulation induction cycles and intrauterine insemination between June 2010 and June 2015. Data was analysed in terms of various parameters affecting clinical pregnancy rates. SPSS 23 was used for statistical analysis.
  
  
  RESULTS
  There were 475 patients having undergone a total of 923 cycles. Pregnancy was established in 133(28%) patients. Univariate analysis of biological/clinical variables revealed the presence of secondary infertility, high endometrial thickness, antral follicle number, post wash total motile sperm count and midluteal progesterone levels following intrauterine insemination to be associated with positive pregnancy outcomes (p<0.05 each). Multiple logistic regression analysis was performed to establish factors that affected the pregnancy rate. The aetiology and type of infertility and high midluteal progesterone levels following intrauterine insemination were found to be statistically significant predictors of pregnancy (p<0.05 each).
  
  
  CONCLUSIONS
  The best chance of pregnancy was found in cases with anovulatory infertility, a history of prior pregnancy, and high midluteal progesterone levels following treatment with gonadotrophins and intrauterine insemination.
authors.affiliation: Kanuni Sultan Suleyman Training and Research Hospital, Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Goncayetkin
authors.initials: G
authors.lastname: Yildirim
authors.affiliation: Kanuni Sultan Suleyman Training and Research Hospital, Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Lale Susan
authors.initials: LS
authors.lastname: Turkgeldi
authors.affiliation: Kanuni Sultan Suleyman Training and Research Hospital, Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Nadiye
authors.initials: N
authors.lastname: Koroglu
authors.affiliation: Kanuni Sultan Suleyman Training and Research Hospital, Obstetrics and Gynecology, Istanbul, Turkey.
authors.affiliation: Kanuni Sultan Suleyman Training and Research Hospital, Obstetrics and Gynecology, Istanbul, Turkey.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000706:statistics & numerical data*; D008297:Male; D010062:Ovulation Induction / Q000706:statistics & numerical data*; D010154:Pakistan / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012189:Retrospective Studies; D055815:Young Adult
keywords: Predictors, Ovarian stimulation, Intrauterine insemination. 