title: A correlation analysis of cone characteristics and central keratometric readings for the different stages of keratoconus.
abstract: BACKGROUND
  Knowledge of the cone characteristics for the different stages of keratoconus may potentially assist practitioners in diagnosing and managing keratoconic patients.
  
  
  OBJECTIVE
  This study aims to determine if any correlation exists between the central keratometric readings and the cone characteristics for the different stages of keratoconus.
  
  
  METHODS
  A university eye clinic.
  
  
  METHODS
  In this retrospective study, a saturated sample of 190 eyes from 106 cases of previously diagnosed keratoconic patient files was analyzed. The stage of keratoconus and cone characteristics, namely, cone location, cone decentration, topographical patterns, and morphology were analyzed using an Oculus 3M corneal topographer.
  
  
  RESULTS
  Analysis revealed a correlation between cone decentration and stage of keratoconus (P = 0.007). The association was found to exist when central K-readings were between 45D and 52D and with an apical cone decentration of 3-4 mm. No correlations were obtained for the stage of keratoconus and the cone location; topography and morphology.
  
  
  CONCLUSIONS
  It can be concluded that cone apices are not central in all stages. Practitioners should consider the peripheral cornea when diagnosing and managing keratoconic patients. No correlation between stage, morphology or topography was respectively revealed.
authors.affiliation: Discipline of Optometry, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Alvin Jeffrey
authors.initials: AJ
authors.lastname: Munsamy
authors.affiliation: Discipline of Optometry, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Vanessa Racquel
authors.initials: VR
authors.lastname: Moodley
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003315:Cornea / Q000473:pathology*; D019781:Corneal Topography / Q000379:methods*; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012720:Severity of Illness Index; D055815:Young Adult