title: Deep brain stimulation of the centromedian thalamic nucleus for essential tremor: a case report.
abstract: The centromedian nucleus (CM) of the thalamus is an important site with anatomical connections to different cortical and subcortical motor areas; however, its role in tremor disorders is not clear, although deep brain stimulation (DBS) of the CM has been described to be effective in the treatment of parkinsonian tremor. We report a case of a patient with medication-refractory essential tremor (ET) who had excellent tremor suppression with DBS of the CM. The CM and the nearby region should be explored as a potential target for the treatment of ET and other forms of tremor.
authors.affiliation: Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA. vibhash3108@gmail.com.|Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA. vibhash3108@gmail.com.
authors.forename: Vibhash D
authors.initials: VD
authors.lastname: Sharma
authors.affiliation: Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Klaus
authors.initials: K
authors.lastname: Mewes
authors.affiliation: Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.|Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Wichmann
authors.affiliation: Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Cathrin
authors.initials: C
authors.lastname: Buetefisch
authors.affiliation: Department of Neurological Surgery, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Jon T
authors.initials: JT
authors.lastname: Willie
authors.affiliation: Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Mahlon
authors.initials: M
authors.lastname: DeLong
mesh_terms: D000368:Aged; D046690:Deep Brain Stimulation / Q000379:methods*; D020329:Essential Tremor / Q000628:therapy*; D006801:Humans; D020646:Intralaminar Thalamic Nuclei; D008297:Male
keywords: Case report; Centromedian nucleus; Deep brain stimulation; Essential tremor