[Pathophysiology of secondary hyperparathyroidism.]
Secondary hyperparathyroidism(SHPT)is the result of a compensatory response of the calcium phosphate homeostatic mechanism. Vitamin D deficiency and chronic kidney disease, both representative pathophysiological causes of SHPT, have been related not only to skeletal disorders but also cardiovascular diseases, ADL and QOL. This relates the importance of SHPT as a pathological cause or marker of such states.
Inagi Municipal Hospital, Department of Nephrology, Japan.
Hiroo
H
Kawarazaki
D002118:Calcium / Q000378:metabolism; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology*; D044169:Receptors, Calcium-Sensing / Q000378:metabolism; D051436:Renal Insufficiency, Chronic / Q000150:complications; D014807:Vitamin D / Q000378:metabolism / Q000627:therapeutic use; D014808:Vitamin D Deficiency / Q000150:complications
D044169:Receptors, Calcium-Sensing; D014807:Vitamin D; D002118:Calcium