Nineteen Years of Adult Congenital Heart Surgery in a Single Center.
Adults with congenital heart disease are a growing population. We describe surgical interventions, short- and long-term mortality and morbidity, and risk factors for adverse events in a population-based cohort.



Patients over or equal to 18 years with congenital heart disease who underwent cardiac surgery at Aarhus University Hospital, Denmark, from 1994 to 2012 were included in the study. Diagnoses, surgical procedures, postoperative complications, and survival were identified in hospital databases, medical records, and the Danish Civil Registration System.



Four hundred seventy-four surgeries were performed in 445 adults (50% men). The median age was 39 years (range 18-83). Thirty-nine percent had previous surgical or catheter-based interventions. Thirty-day and in-hospital mortality were 1.1%. Postoperative complications occurred in 50% of cases, most were minor such as temporary arrhythmias and pneumonia. Major complications included postoperative bleeding necessitating intervention (6%), stroke (2%), and acute temporary renal failure (1%). Multivariate analysis identified RACHS-1 categories over or equal to 3 compared to category 1 (odds ratio (OR) = 2.3; 95% confidence interval (CI): 1.5-3.7), New York Heart Association functional class III and IV compared to class I (OR = 2.2; 95% CI: 1.3-3.7) and age at surgery (OR = 1.03, 95% CI: 1.01-1.04), as risk factors for adverse events. Survival during a median follow-up of 7.8 years (range 0 days-21.4 years) was 85% (95% CI: 80%-89%).



Adults with congenital heart disease constitute a growing population with the need for cardiac surgery. Postoperative complications are frequent but early and late mortality are low.
1 Department of Cardiothoracic Surgery, Aarhus University Hospital, Aarhus, Denmark.
Madurra
M
Perinpanayagam
2 Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Signe H
SH
Larsen
2 Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Kristian
K
Emmertsen
3 Department of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Marianne B
MB
Møller
1 Department of Cardiothoracic Surgery, Aarhus University Hospital, Aarhus, Denmark.
Vibeke E
VE
Hjortdal
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures / Q000706:statistics & numerical data*; D016208:Databases, Factual; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005544:Forecasting; D006330:Heart Defects, Congenital / Q000453:epidemiology / Q000601:surgery*; D017052:Hospital Mortality / Q000639:trends; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D016017:Odds Ratio; D011183:Postoperative Complications / Q000453:epidemiology*; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends; D055815:Young Adult
adult congenital heart disease; complications; morbidity; mortality; surgery