First report of OXA-232-producing Klebsiella pneumoniae strains in Tunisia.
Eleven carbapenem-resistant Klebsiella pneumoniae isolates were recovered from the military hospital of Tunis, Tunisia. Three of these isolates carried the carbapenemase blaOXA-232gene recently identified in France. These isolates were clonally related and co-expressed the extended-spectrum ß-lactamase, CTX-M-15. This work identified the occurrence of OXA-232 producers in North-African countries.
EA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Laboratory of Microbiology, Military Hospital of Tunis, Monfleury, Tunisia.
Hella
H
Lahlaoui
EA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Associated French National Reference Center for Antibiotic Resistance: Carbapenemase-producing Enterobacteriaceae, Le Kremlin-Bicêtre, France; Evolution and Ecology of Resistance to Antibiotics Unit, Institut Pasteur-APHP-Université Paris Sud, Paris, France. Electronic address: remy.bonnin@u-psud.fr.
Rémy A
RA
Bonnin
Laboratory of Microbiology, Military Hospital of Tunis, Monfleury, Tunisia.
Mohamed Ben
MB
Moussa
Laboratory of Microbiology, Hospital Tahar Sfar, Mahdia, Tunisia.
Anis Ben Haj
ABH
Khelifa
EA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Associated French National Reference Center for Antibiotic Resistance: Carbapenemase-producing Enterobacteriaceae, Le Kremlin-Bicêtre, France; Evolution and Ecology of Resistance to Antibiotics Unit, Institut Pasteur-APHP-Université Paris Sud, Paris, France.
Thierry
T
Naas
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D015780:Carbapenems / Q000494:pharmacology; D052978:Disk Diffusion Antimicrobial Tests; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D058885:Multilocus Sequence Typing; D014416:Tunisia / Q000453:epidemiology; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D015780:Carbapenems; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases; C000626016:beta-lactamase OXA-232, Klebsiella pneumoniae; C063912:carbapenemase
Carbapenemase; Enterobacteriaceae; OXA-232