Herpes simplex virus in erythrokeratoderma variabilis.
We report a 48 -year-old woman witherythrokeratoderma variabilis, which is a rarehereditary disorder of keratinization, who developednew, painful, blisters within her skin lesions. Thediagnosis of herpes simplex virus infection was madebased on the clinical history and histopathologicfeatures. She was successfully treated withprophylactic valacyclovir, and her herpetic outbreakshave halted. This case serves as a reminder thateven among the most rare skin disorders, commonsecondary complications may be easily overlooked.
Ronald O. Perelman Department of Dermatology, NYU School of Medicine, NYU Langone Medical Center.
Shields
S
Callahan
Euphemia
E
Mu
Randie H
RH
Kim
Shane A
SA
Meehan
Paul
P
Possick
D000005:Abdomen; D000212:Acyclovir / Q000031:analogs & derivatives / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D001132:Arm; D056266:Erythrokeratodermia Variabilis / Q000150:complications*; D005148:Facial Dermatoses / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007866:Leg; D008875:Middle Aged; D018139:Simplexvirus; D035441:Thoracic Wall; D000077483:Valacyclovir; D014633:Valine / Q000031:analogs & derivatives / Q000627:therapeutic use
D000998:Antiviral Agents; D014633:Valine; D000077483:Valacyclovir; D000212:Acyclovir