Strategies and Outcomes of Repeat Mitral Valve Interventions after Failed MitraClip Therapy.
Percutaneous mitral valve repair (PMVR) with the MitraClip system (Abbott Vascular, Santa Clara, CA, USA) is a valid therapeutic option for patients with severe mitral regurgitation (MR) deemed to be at high or prohibitive surgical risk. Despite the reassuring data on efficacy and long-term durability of the procedure, the proportion of patients with residual or relapsing severe MR after MitraClip therapy is not negligible. In light of the detrimental prognostic impact of severe MR, repeat interventions are increasingly performed in clinical practice using different techniques. In high-risk settings, percutaneous procedures have proven to be effective and safe at reducing MR. Building on this, we sought to summarize the current landscape and clinical experience of reinterventions after failed MitraClip therapy, so as to assist physicians facing the clinical hurdle of proper treatment management after failed PMVR.
Division of Cardiology, Ferrarotto Hospital, University of Catania, Catania, Italy.
Carmelo
C
Grasso
Sergio
S
Buccheri
Davide
D
Capodanno
Antonio
A
Popolo Rubbio
Maria Elena
ME
Di Salvo
Salvatore
S
Scandura
Sarah
S
Mangiafico
Tatiana
T
Salerno
Stefano
S
Cannata
Veronica
V
Dezio
Giuseppe
G
Castania
Marco
M
Barbanti
Piera
P
Capranzano
Corrado
C
Tamburino
D000368:Aged; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D017548:Echocardiography, Transesophageal; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000628:therapy*; D012008:Recurrence; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome
Mitral regurgitation; Percutaneous mitral valve repair; Repeat interventions