Metastatic neuroendocrine carcinoma in the skin.
Cutaneous metastases secondary to neuroendocrinetumors are rare. Herein we report a case of a 75-yearoldwoman who presented with a rare cutaneousmetastatic disease. She was previously diagnosed withmetastatic neuroendocrine carcinoma of unknownprimary, with metastases to liver, lung, and bone.Biopsy of the skin lesion demonstrated archetypicalpathology and positive immunohistochemicalstaining for chromogranin A and synaptophysin. Thepatient started palliative chemo-radiation therapyand passed away soon after.
Andres
A
Garcia
Steven
S
Mays
Department of Dermatology, University of Texas McGovern Medical School at Houston. sirunya.silapunt@uth.tmc.edu.
Sirunya
S
Silapunt
D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary*; D018278:Carcinoma, Neuroendocrine / Q000378:metabolism / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000556:secondary*; D008175:Lung Neoplasms / Q000556:secondary*; D009382:Neoplasms, Unknown Primary / Q000378:metabolism / Q000473:pathology; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary*