A Review of Phage Therapy against Bacterial Pathogens of Aquatic and Terrestrial Organisms.
Since the discovery of bacteriophage in the early 1900s, there have been numerous attempts to exploit their innate ability to kill bacteria. The purpose of this report is to review current findings and new developments in phage therapy with an emphasis on bacterial diseases of marine organisms, humans, and plants. The body of evidence includes data from studies investigating bacteriophage in marine and land environments as modern antimicrobial agents against harmful bacteria. The goal of this paper is to present an overview of the topic of phage therapy, the use of phage-derived protein therapy, and the hosts that bacteriophage are currently being used against, with an emphasis on the uses of bacteriophage against marine, human, animal and plant pathogens.
Old Dominion University, Department of Biological Sciences, 5115 Hampton Blvd, Norfolk, VA 23529, USA. jdoss003@odu.edu.
Janis
J
Doss
Old Dominion University, Department of Biological Sciences, 5115 Hampton Blvd, Norfolk, VA 23529, USA. kculb004@odu.edu.
Kayla
K
Culbertson
Old Dominion University, Department of Biological Sciences, 5115 Hampton Blvd, Norfolk, VA 23529, USA. dhahn001@odu.edu.
Delilah
D
Hahn
Old Dominion University, Department of Biological Sciences, 5115 Hampton Blvd, Norfolk, VA 23529, USA. jcama008@odu.edu.
Joanna
J
Camacho
Old Dominion University, Department of Biological Sciences, 5115 Hampton Blvd, Norfolk, VA 23529, USA. nbarekzi@odu.edu.
Nazir
N
Barekzi
D000818:Animals; D001424:Bacterial Infections / Q000628:therapy*; D006801:Humans; D000071059:Phage Therapy; D010944:Plants
Vibrio phage; aquaculture; bacteriophage; phage therapy