DNA-functionalized photonic crystal microspheres for multiplex detection of toxic metal ions.
A novel type of suspension array for multiplex detection of heavy metal ions with photonic crystal hydrogel microspheres was reported. The photonic crystal hydrogel microspheres have close-packed photonic crystal particles as their encoding units and ssDNA-functionalized hydrogel as the sensing units. The developed microspheres were successfully applied in multiplex detection of heavy metal ions.
Key Laboratory of Biomedical Functional Materials, School of Science, China Pharmaceutical University, Tongjia Xiang 24, Nanjing, Jiangsu, 210009, PR China.
Zhengyu
Z
Yan
Key Laboratory of Biomedical Functional Materials, School of Science, China Pharmaceutical University, Tongjia Xiang 24, Nanjing, Jiangsu, 210009, PR China.
Chunqing
C
Tian
Key Laboratory of Biomedical Functional Materials, School of Science, China Pharmaceutical University, Tongjia Xiang 24, Nanjing, Jiangsu, 210009, PR China.
Xincheng
X
Qu
Key Laboratory of Biomedical Functional Materials, School of Science, China Pharmaceutical University, Tongjia Xiang 24, Nanjing, Jiangsu, 210009, PR China. Electronic address: shenweiyang@cpu.edu.cn.
Weiyang
W
Shen
Key Laboratory of Biomedical Functional Materials, School of Science, China Pharmaceutical University, Tongjia Xiang 24, Nanjing, Jiangsu, 210009, PR China. Electronic address: baofen_ye@163.com.
Baofen
B
Ye
D052160:Benzothiazoles; D002412:Cations / Q000032:analysis; D003460:Crystallization; D015342:DNA Probes; D004277:DNA, Single-Stranded; D003959:Diamines; D005456:Fluorescent Dyes; D006801:Humans; D020100:Hydrogels; D019216:Metals, Heavy / Q000032:analysis* / Q000633:toxicity; D008863:Microspheres; D055620:Optical Phenomena; D009930:Organic Chemicals; D011804:Quinolines; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity
D052160:Benzothiazoles; D002412:Cations; D015342:DNA Probes; D004277:DNA, Single-Stranded; D003959:Diamines; D005456:Fluorescent Dyes; D020100:Hydrogels; D019216:Metals, Heavy; D009930:Organic Chemicals; D011804:Quinolines; D014874:Water Pollutants, Chemical; C098022:SYBR Green I
Aptamer; Colloidal crystal; Heavy metal ions; Multiplex assay; Photonic crystal