Clinical applications of topical ivermectin in dermatology.
Ivermectin (IVM) is a broad-spectrum anti-parasitic drug with significant anti-inflammatory properties. The emergence of treatment resistance to lindane, permethrin, and possibly malathion complicates the global strategy for management of common parasitic skin diseases such as scabies and head lice. In this regard. IVM has been safely and effectively used in the treatment of these common human infestations. In addition, IVM may be useful in inflammatory cutaneous disorders such as papulopustular rosacea where demodex may play a role in pathogenesis. Herein, we review the current applications of topical IVM in dermatology.
Omid
O
Zargari
Razi Dermatology Hospital, Tehran University of Medical Sciences, Tehran. n-aghazadeh@sina.tums.ac.ir.
Nessa
N
Aghazadeh
Fatemeh
F
Moeineddin
D000279:Administration, Cutaneous; D000977:Antiparasitic Agents / Q000627:therapeutic use*; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use*; D010373:Lice Infestations / Q000188:drug therapy*; D008924:Mite Infestations / Q000188:drug therapy; D009198:Myiasis / Q000188:drug therapy*; D012393:Rosacea / Q000188:drug therapy*; D012532:Scabies / Q000188:drug therapy*; D012536:Scalp Dermatoses / Q000188:drug therapy*
D000977:Antiparasitic Agents; D007559:Ivermectin