Meta-analysis of Transhiatal Esophagectomy in carcinoma of esophagogastric junction, does it have an advantage?
OBJECTIVE
Compare the clinical outcome of Transhiatal Esophagectomy (THE) approach and open Thoracic Esophagectomy (TTE) approach in the carcinoma of esophagogastric junction (CEGJ).


METHODS
Relevant literature published until 2016 from PubMed, Cochrane Library, Ovid (Medline) and EMBASE were retrieved. Meta-analysis was achieved by using the Stata12 software.


RESULTS
A total of 18 studies and 2202 cases of patients were involved in this meta-analysis. THE showed to decrease the hospital stay, hospital mortality, surgical time, and blood loss in the operation. However, fewer lymph nodes would be yielded by this surgical option. A 5-year survival advantage of THE was only observed in North America subgroup.


CONCLUSIONS
Except the above operative related advantages, there was no clear evidence that THE has a further advantage in CEGJ.
Department of Surgical Oncology, First Affiliated Hospital of Xi'an JiaoTong University, Xi'an, China.
Rong
R
Yan
Department of Surgical Oncology, First Affiliated Hospital of Xi'an JiaoTong University, Xi'an, China. Electronic address: dangchengxue@mail.xjtu.edu.cn.
Chengxue
C
Dang
D004938:Esophageal Neoplasms / Q000401:mortality / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D004943:Esophagogastric Junction / Q000473:pathology; D006801:Humans
CEGJ; Meta-analysis; Thoracotomy; Transhiatal Esophagectomy