Update on viral hepatitis in pregnancy.
Pregnant women with acute viral hepatitis are at higher risk of morbidity and death than pregnant women with chronic viral hepatitis. The risk of death is highest with acute viral hepatitis E, and the rate of transmission to the baby may be highest with hepatitis B virus (HBV) infection. Managing viral hepatitis in pregnancy requires assessing the risk of transmission to the baby, determining the gestational age at the time of infection and the mother's risk of decompensation, and understanding the side effects of antiviral drugs.
Department of Cellular and Molecular Medicine, and Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Zhili
Z
Shao
Section of Hepatology, Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH, USA.
Mohammad
M
Al Tibi
Section of Hepatology, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, USA. fleminj1@ccf.org.
Jamile
J
Wakim-Fleming
D000998:Antiviral Agents / Q000627:therapeutic use*; D005260:Female; D005865:Gestational Age; D006525:Hepatitis, Viral, Human / Q000188:drug therapy* / Q000635:transmission / Q000821:virology; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000821:virology; D018570:Risk Assessment; D012307:Risk Factors
D000998:Antiviral Agents