Interleukin-17: Why the Worms Squirm.
IL-17 is a cytokine known primarily for its role in inflammation. In a recent issue of Nature, Chen et al. (2017) demonstrate that IL-17 plays a neuromodulatory role in Caenorhabditis elegans by acting directly on neurons to amplify neuronal responses to stimuli and produce changes in animal behavior.
Division of Infectious Diseases and Immunology and Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Noah J
NJ
Silverstein
Division of Infectious Diseases and Immunology and Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: jun.huh@umassmed.edu.
Jun R
JR
Huh
D000818:Animals; D001522:Behavior, Animal; D017173:Caenorhabditis elegans; D020381:Interleukin-17; D009474:Neurons
D020381:Interleukin-17