Prenatal prediction of pulmonary hypoplasia.
Pulmonary hypoplasia, although rare, is associated with significant neonatal morbidity and mortality. Conditions associated with pulmonary hypoplasia include those which limit normal thoracic capacity or movement, including skeletal dysplasias and abdominal wall defects; those with mass effect, including congenital diaphragmatic hernia and pleural effusions; and those with decreased amniotic fluid, including preterm, premature rupture of membranes, and genitourinary anomalies. The ability to predict severe pulmonary hypoplasia prenatally aids in family counseling, as well as obstetric and neonatal management. The objective of this review is to outline the imaging techniques that are widely used prenatally to assess pulmonary hypoplasia and to discuss the limitations of these methods.
Department of Obstetrics and Gynecology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Jourdan E
JE
Triebwasser
Department of Obstetrics and Gynecology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: mtread@med.umich.edu.
Marjorie C
MC
Treadwell
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology / Q000503:physiopathology; D005260:Female; D047109:Fetal Development; D006801:Humans; D008168:Lung / Q000002:abnormalities* / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology / Q000503:physiopathology; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000196:embryology / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000639:trends; D009929:Organ Size; D011247:Pregnancy; D012720:Severity of Illness Index; D018608:Ultrasonography, Doppler / Q000639:trends; D016216:Ultrasonography, Prenatal / Q000639:trends
Lung volume; Prenatal diagnosis; Pulmonary hypoplasia