The Skull Vibration-Induced Nystagmus Test of Vestibular Function-A Review.
A 100-Hz bone-conducted vibration applied to either mastoid induces instantaneously a predominantly horizontal nystagmus, with quick phases beating away from the affected side in patients with a unilateral vestibular loss (UVL). The same stimulus in healthy asymptomatic subjects has little or no effect. This is skull vibration-induced nystagmus (SVIN), and it is a useful, simple, non-invasive, robust indicator of asymmetry of vestibular function and the side of the vestibular loss. The nystagmus is precisely stimulus-locked: it starts with stimulation onset and stops at stimulation offset, with no post-stimulation reversal. It is sustained during long stimulus durations; it is reproducible; it beats in the same direction irrespective of which mastoid is stimulated; it shows little or no habituation; and it is permanent-even well-compensated UVL patients show SVIN. A SVIN is observed under Frenzel goggles or videonystagmoscopy and recorded under videonystagmography in absence of visual-fixation and strong sedative drugs. Stimulus frequency, location, and intensity modify the results, and a large variability in skull morphology between people can modify the stimulus. SVIN to 100 Hz mastoid stimulation is a robust response. We describe the optimum method of stimulation on the basis of the literature data and testing more than 18,500 patients. Recent neural evidence clarifies which vestibular receptors are stimulated, how they cause the nystagmus, and why the same vibration in patients with semicircular canal dehiscence (SCD) causes a nystagmus beating toward the affected ear. This review focuses not only on the optimal parameters of the stimulus and response of UVL and SCD patients but also shows how other vestibular dysfunctions affect SVIN. We conclude that the presence of SVIN is a useful indicator of the asymmetry of vestibular function between the two ears, but in order to identify which is the affected ear, other information and careful clinical judgment are needed.
Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital, Grenoble, France; EA 3450 DevAH, Development, Adaptation and Disadvantage, Faculty of Medicine and UFR STAPS, University of Lorraine, Villers-lès-Nancy, France.
Georges
G
Dumas
Vestibular Research Laboratory, School of Psychology, the University of Sydney , Sydney, NSW , Australia.
Ian S
IS
Curthoys
EA 3450 DevAH, Development, Adaptation and Disadvantage, Faculty of Medicine and UFR STAPS, University of Lorraine, Villers-lès-Nancy, France; Sports Medicine Research Laboratory, Luxembourg Institute of Health, Strassen, Luxembourg.
Alexis
A
Lion
EA 3450 DevAH, Development, Adaptation and Disadvantage, Faculty of Medicine and UFR STAPS, University of Lorraine, Villers-lès-Nancy, France; Department of Paediatric Oto-Rhino-Laryngology, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France.
Philippe
P
Perrin
Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital, Grenoble, France; INSERM UMR 2015, Grenoble, France.
Sébastien
S
Schmerber
high frequencies; nystagmus; skull vibration; vertigo; vestibular disease