Necrolytic migratory erythema associated with fatty liver disease and the psuedoglucagonoma syndrome.
We report a 48-year-old woman with a past medical history of psoriasis, nonalcoholic steatohepatitis (NASH), and type II diabetes mellitus, who presented to the emergency department with a 1 week history of erosive annular plaques with associated atrophy and telangiectasias on her legs bilaterally, thighs and buttock, histopathologically consistent with necrolytic migratory erythema. Although classically associated with a pancreatic glucagonoma, this patient experienced this figurate erythema in the setting of fatty liver disease with no glucagonoma. The rarity of pseudoglucagonoma syndrome, or necrolytic migratory erythema occurring in the absence of a glucagonoma, warranted the discussion of this case.
Collin
C
Fuller
Jaimie
J
Glick
Shelly
S
Rivas
Hofstra Northwell School of Medicine, Department of Dermatology, Hempstead. kburris@northwell.edu.
Katy
K
Burris
D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D007868:Leg Dermatoses / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D058568:Necrolytic Migratory Erythema / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications*