Disarming the Killers: Brain Strikes on NK Cells.
Brain ischemia induces profound systemic immunosuppression, leading to infectious complications. In this issue of Immunity, Liu et al. (2017) demonstrate that distinct neuroendocrine pathways differentially inhibit natural killer (NK) cell responses in the central nervous system and the periphery after cerebral infarction.
Centre d'Immunologie de Marseille-Luminy, Aix Marseille Univ, CNRS, INSERM, 13288 Marseille, France.
Linda
L
Quatrini
Centre d'Immunologie de Marseille-Luminy, Aix Marseille Univ, CNRS, INSERM, 13288 Marseille, France. Electronic address: ugolini@ciml.univ-mrs.fr.
Sophie
S
Ugolini
D001921:Brain; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*