Validity and reliability of the multidimensional assessment of fatigue scale in Iranian patients with relapsing-remitting subtype of multiple sclerosis.
OBJECTIVE
The purpose of this study is to investigate the validity and reliability of the Persian version of the Multidimensional Assessment of Fatigue Scale (MAFS) in an Iranian population with multiple sclerosis.


METHODS
A self-reported survey on fatigue including the MAFS, Fatigue Impact Scale and demographic measures was completed by 130 patients with multiple sclerosis and 60 healthy persons sampled with a convenience method. Test-retest reliability and validity were evaluated 3 days apart. Construct validity of the MAFS was assessed with the Fatigue Impact Scale.


RESULTS
The MAFS had high internal consistency (Cronbach's alpha >0.9) and 3-d test-retest reliability (intraclass correlation coefficient = 0.99). Correlation between the Fatigue Impact Scale and MAFS was high (r = 0.99). Correlation between MAFS scores and the Expanded Disability Status Scale was also strong (r = 0.85). Questionnaire items showed acceptable item-scale correlation (0.968-0.993).


CONCLUSIONS
The Persian version of the MAFS appears to be a valid and reliable questionnaire. It is an appropriate short multidimensional instrument to assess fatigue in patients with multiple sclerosis in clinical practice and research. Implications for Rehabilitation The Persian version of Multidimensional Assessment of Fatigue is a valid and reliable instrument for the assessment and monitoring the fatigue in Persian-language patients with multiple sclerosis. It is very easy to administer and a time efficient scale in comparison to other instruments evaluating fatigue in patients with multiple sclerosis.
a School of Rehabilitation Sciences, Department of Physical Therapy , Shiraz University of Medical Sciences , Shiraz , IR Iran.
Shabnam
S
Behrangrad
a School of Rehabilitation Sciences, Department of Physical Therapy , Shiraz University of Medical Sciences , Shiraz , IR Iran.
Amin
A
Kordi Yoosefinejad
D000328:Adult; D004185:Disability Evaluation; D005221:Fatigue / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000150:complications / Q000453:epidemiology / Q000534:rehabilitation; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards; D064232:Visual Analog Scale
Construct validity; cross-cultural adaptation; expanded disability status scale; internal consistency; test–retest reliability