Human T-Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis: The First Case Report in Southeast Asia.
Human T-lymphotropic virus type-1 (HTLV-1) infection was diagnosed in a Thai patient with chronic progressive myelopathy. The phylogenetic tree of the ltr sequencing of HTLV-1 indicated that the virus belongs to the transcontinental genotype of the cosmopolitan subtype A. This is the first case report of HTLV-1-associated myelopathy in Southeast Asia. Awareness of HTLV-1 and related condition should be encouraged in this region and routine screening should be applied to blood donors.
1 Department of Medicine, Faculty of Medicine, Chulalongkorn University , Bangkok, Thailand .
Sekh
S
Thanprasertsuk
1 Department of Medicine, Faculty of Medicine, Chulalongkorn University , Bangkok, Thailand .
Suwapan
S
Pleumkanitkul
2 WHO Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital , Bangkok, Thailand .
Supaporn
S
Wacharapluesadee
2 WHO Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital , Bangkok, Thailand .
Teerada
T
Ponpinit
1 Department of Medicine, Faculty of Medicine, Chulalongkorn University , Bangkok, Thailand .|2 WHO Collaborating Centre for Research and Training on Viral Zoonoses, King Chulalongkorn Memorial Hospital , Bangkok, Thailand .
Thiravat
T
Hemachudha
1 Department of Medicine, Faculty of Medicine, Chulalongkorn University , Bangkok, Thailand .
Chusana
C
Suankratay
D005260:Female; D005838:Genotype; D015490:HTLV-I Infections / Q000175:diagnosis* / Q000473:pathology*; D015368:Human T-lymphotropic virus 1 / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008875:Middle Aged; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D020079:Terminal Repeat Sequences; D013785:Thailand
Southeast Asia; Thailand; human T-lymphotropic virus-1; paraparesis; spinal cord diseases; tropical spastic