The predictive value of baseline LDL-TG level on major adverse cardiovascular events in a followed up cohort population.
We aimed at identifying the predictive roles of Low-Density Lipoprotein Triglycerides (LDL-TG) for major adverse cardiovascular events (MACEs).



A longitudinal study in a routine health check-up population was performed with an average follow-up of 4.8 years. The participants involved in this study were 1680, from 2007 to 2009, and all had followed-up for all-cause mortality, cardiovascular disease mortality, and the development of MACEs. The demographic information and anthropometric parameters at baseline were recorded. The baseline and follow-up conventional lipid parameters were measured. We also examined the level LDL-TG, as well as the relationship between its level and MACEs.



MACEs individuals were characterized by statistically higher baseline LDL-TG (17.22 ± 8.05 vs. 16.39 ±7.35 nmol/l, p = 0.017). The univariate regression for MACEs group indicated that the LDL-TG (b = 0.813, HR = 2.254, 95% CI: 1.454-3.494, p < 0.001), older age, sex and other factors were a significant risk for MACEs. Furthermore, in the adjusted Cox model showed that only higher baseline LDL-TG (b =0.512, HR = 1.669, 95% CI: 1.013-2.748, p = 0.044) and older age (b = 0.062, HR = 1.064, 95% CI: 1.034-1.094, p < 0.001, Table IV) were still predictors for MACEs.



Higher baseline LDL-TG closely associated with MACEs and it is a moderate and independent predictive factor for MACEs.
Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China. yeping301@sina.com.
X-H
XH
Ding
P
P
Ye
X-N
XN
Wang
R-H
RH
Cao
X
X
Yang
W-K
WK
Xiao
Y
Y
Zhang
Y-Y
YY
Bai
H-M
HM
Wu
D002318:Cardiovascular Diseases; D008078:Cholesterol, LDL; D006801:Humans; D008077:Lipoproteins, LDL; D008137:Longitudinal Studies; D011379:Prognosis; D016016:Proportional Hazards Models; D012307:Risk Factors; D014280:Triglycerides
D008078:Cholesterol, LDL; D008077:Lipoproteins, LDL; D014280:Triglycerides; C032607:low density lipoprotein triglyceride