Prevalence of Cervical Infection and Genotype Distribution of Human Papilloma Virus Among Females in Da Nang, Vietnam.
The goal of the present study was to determine the prevalence and distribution of high-risk human papilloma virus (HPV) genotypes in women from two districts in and around Da Nang city, Vietnam.



All participants were randomly selected, 200 from the Hai Chau district and 200 from the Son Tra district. The detection and genotyping of HPV were performed by real-time polymerase chain reaction (PCR) technique.



Out of a total of 400 women, we found that 38 (9.5%) were infected with a high-risk HPV genotype, the most prevalent genotypes being 16, 18, 58 and 59. By assessment of the HPV findings in relation to sociodemographic characteristics, we found significant differences between the two study districts and between the age groups, as well as differences associated with occupation and the use of contraceptives.



The proportion of high-risk genotypes other than 16 and 18 was relatively high, and since the HPV genotype distribution is known to vary greatly across populations, the information from this study can be used for planning of screening and vaccination programs in Da Nang.
Department of Medical Laboratory, Da Nang University of Medical Technology and Pharmacy, Da Nang, Vietnam.
Song Nguyen
SN
Van
Department of Medical Laboratory, Da Nang University of Medical Technology and Pharmacy, Da Nang, Vietnam.
Minh Nguyen
MN
Khac
Department of Natural Science and Biomedicine, School of Health and Welfare, Jönköping University, Jönköping, Sweden.
Jan
J
Dimberg
Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden.|Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, University Hospital Huddinge, Stockholm, Sweden.|Clinical Microbiology, Division of Medical Diagnostics, Region Jönköping County, Jönköping, Sweden.
Andreas
A
Matussek
Clinical Microbiology, Division of Medical Diagnostics, Region Jönköping County, Jönköping, Sweden anna.jonsson.henningsson@rjl.se.
Anna J
AJ
Henningsson
D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000821:virology; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008403:Mass Screening; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics*; D030361:Papillomavirus Infections / Q000208:ethnology / Q000821:virology*; D015995:Prevalence; D060888:Real-Time Polymerase Chain Reaction; D012306:Risk; D012923:Social Class; D002583:Uterine Cervical Neoplasms / Q000208:ethnology / Q000821:virology*; D014744:Vietnam / Q000453:epidemiology; D055815:Young Adult
D004279:DNA, Viral
Cervical cancer; Vietnam; high-risk HPV genotype; human papilloma virus; prevalence