Gabapentin-induced aquagenic wrinkling of the palms.
Aquagenic keratoderma (AK) or aquagenic wrinklingis a rare palmoplantar skin disease. It is sporadic orhereditary condition. It appears in childhood or youngadulthood and it is seen as multiple asymptomaticsmall shiny papules on the peripheral margin ofpalms and/or soles after submersion in water. Thepathogenesis and etiology of ASA remains unclear.Drugs sometimes trigger AK. Herein, we present thecase of a 29-year-old man who had begun treatmentwith gabapentin three weeks before the onset of hiscutaneous symptoms.
Bezmialem Vakif University, Dermatology, Istanbul, Turkey. dr.nazanyilmaz@hotmail.com.
Nazan
N
Emiroglu
Fatma P
FP
Cengiz
Ozlem
O
Su
Nahide
N
Onsun
D000328:Adult; D000588:Amines / Q000009:adverse effects*; D000700:Analgesics / Q000009:adverse effects*; D003509:Cyclohexanecarboxylic Acids / Q000009:adverse effects*; D000077206:Gabapentin; D006229:Hand Dermatoses / Q000209:etiology*; D006801:Humans; D008297:Male; D009437:Neuralgia / Q000188:drug therapy*; D012867:Skin; D014867:Water; D005680:gamma-Aminobutyric Acid / Q000009:adverse effects*
D000588:Amines; D000700:Analgesics; D003509:Cyclohexanecarboxylic Acids; D014867:Water; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin