Treatment of cerebrospinal fluid leak after spine surgery.
Owing to the complexity of spinal surgery, there is a great prevalence of dural tear causing cerebrospinal fluid (CSF) leakage. Many studies focused on suture repair for dural tear to stop CSF leak. Now some new treatment strategies have shown a promising effect that is listed as follows: 1) creating watertight dural closure to stop CSF leak with the help of dural substitute material; and 2) retarding CSF leak by changing pressure difference, including reducing the subarachnoid fluid pressure, increasing the epidural space pressure and both. In fact several methods mentioned above are usually combined to treat CSF leak. However, no update review summarized the relevant studies implemented in recent years. In this review, the authors would compare the effects of different dural closure techniques, and introduce the latest treatment methods and mechanisms.
Department of Spine Surgery, Tianjin Union Medical Centre, Tianjin 300121, China.
Zhao
Z
Fang
Department of Spine Surgery, Tianjin Union Medical Centre, Tianjin 300121, China. Electronic address: founder2011@163.com.
Rong
R
Tian
Department of Spine Surgery, Tianjin Union Medical Centre, Tianjin 300121, China.
Yu-Tao
YT
Jia
Department of Spine Surgery, Tianjin Union Medical Centre, Tianjin 300121, China.
Tian-Tong
TT
Xu
Department of Spine Surgery, Tianjin Union Medical Centre, Tianjin 300121, China.
Yang
Y
Liu
D017217:Blood Patch, Epidural; D065634:Cerebrospinal Fluid Leak / Q000517:prevention & control / Q000628:therapy*; D004388:Dura Mater / Q000601:surgery*; D006801:Humans; D013536:Suture Techniques
Cerebralspinal fluid leak; Spine; Therapeutics