Myocardial Infarction. Pathological Relevance and Relationship with Coronary Risk Factors.
Three types of necrosis characterize MI: coagulation necrosis, typically due to a coronarogenic mechanism, coagulative myocytolysis with formation of contract bands as an effect of sympathetic nervous system and adrenergic stimulation, and colliquative myocytolysis, characterized by myocardial fiber lysis, which is a close result of hydrolytic enzyme activity deriving from the material reaching the infarct area.



Although a multifactorial etiology may be identified, nevertheless coronary alterations, which are a consequence of atherosclerotic plaque formation and complications with a reduced blood flow supply to the myocardium, are the benchmark of MI.



Evidence indicates a close relationship between the MI and some coronary risk factors, associated with this pathologic pattern with a different, but high rate.



Precipitating events to cause acute myocardial pathology need, however, to develop an acute myocardial infarction.
Castelnuovo Magra. Italy.
Aurelio
A
Leone
D000818:Animals; D003327:Coronary Disease / Q000453:epidemiology / Q000473:pathology*; D003331:Coronary Vessels / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000473:pathology; D009203:Myocardial Infarction / Q000453:epidemiology / Q000473:pathology*; D009765:Obesity / Q000453:epidemiology / Q000473:pathology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology / Q000473:pathology
Myocardial infarction; catecholamine release; coronary
risk factor(s).; coronary pathology; myocardial necrosis; sympathetic nervous system