A case report: Liraglutide as a novel treatment option in late dumping syndrome.
BACKGROUND
Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging.


METHODS
New-onset postsurgical late dumping syndrome after Toupet fundoplication.


METHODS
Sigstad Score, OGTT, CGM.


METHODS
Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg).


RESULTS
Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events.


CONCLUSIONS
Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery.
Department of Obesity and Metabolic Surgery, Sana Klinikum Offenbach, Offenbach am Main, Germany.
Sonja
S
Chiappetta
Christine
C
Stier
D005260:Female; D018662:Fundoplication / Q000009:adverse effects; D006801:Humans; D006946:Hyperinsulinism / Q000188:drug therapy* / Q000209:etiology; D007003:Hypoglycemia / Q000188:drug therapy* / Q000209:etiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D000069450:Liraglutide / Q000627:therapeutic use*; D008875:Middle Aged; D019518:Postprandial Period; D013577:Syndrome
D007004:Hypoglycemic Agents; D000069450:Liraglutide