Spectral Analysis of Polysomnography in Narcolepsy.
OBJECTIVE
This study was conducted to identify differences between people with narcolepsy and the normal control of delta and theta activity using electroencephalogram (EEG) spectrum analysis of nocturnal polysomnography (PSG).


METHODS
Seven narcolepsy patients and seven age-sex matched normal controls underwent PSG and multiple sleep latency tests. Participants' non-rapid eye movement (NREM) sleep EEGs in PSG was analyzed using a Fast Fourier Transform technique.


RESULTS
While NREM delta activity of people with narcolepsy declined during the first three periods of NREM, there was no change during the 4th period of NREM. The increase in NREM theta activity also lasted until the 3rd period of NREM but did not occur during the 4th period of NREM. In comparing sleep parameters, REM sleep latency in the narcolepsy group was significantly shorter than in controls.


CONCLUSIONS
These results suggest that people with narcolepsy are likely to have a delta and theta activity-related sleep disturbance mechanism in NREM sleep.
Department of Neuropsychiatry, Yeungnam University, Daegu, Republic of Korea.
Seok Ho
SH
Yun
Department of Psychiatry, Motherth Hospital, Ulsan, Republic of Korea.
Ho Dong
HD
Choi
Department of Neuropsychiatry, Yeungnam University, Daegu, Republic of Korea.
Wan Seok
WS
Seo
Delta activity; Electroencephalogram; Narcolepsy; Spectral analysis; Theta activity