[Pilot study of psychiatric and social aspects of children and adolescents with fragile X syndrome].
The study describes the burden of psychosocial risks of mental illnesses and the ways in which children and adolescents with fragile X syndrome (FRX) can be treated.



Data from a sample of 34 patients with FRX younger than 18 years stemming from a prospective multicenter (n = 11) registry study (EXPLAIN) were analyzed with regard to psychosocial burden and Treatment.



One third of all participants reported having relatives who suffer from FRX. The majority of participants were suffering themselves from one kind or another mental or neurological problems. Younger participants (< 14 years) tended to suffer from atactic disorders, epileptic seizures, and autistic symptoms. These disorders were usually treated by psychotropic drugs supplemented by logopedic therapies and occupational therapies (more than once a month). In our sample, 96.3 % of the younger patients and more than 57.1 % of the older patients were still living with their parents.



Patients with FRX often suffer from additional neurological and mental disorders. For that reason, they should be diagnosed and treated early on.
1 Klinik für Psychiatrie, Neurologie, Psychosomatik und Psychotherapie im Kindes- und Jugendalter der Universitätsmedizin Rostock.
Frank
F
Häßler
2 Abt. Psychiatrische Therapie für Menschen mit Geistiger Behinderung, Isar Amper Klinikum gGmbH, Klinikum München Ost, Haar.
Franziska
F
Gaese
3 Experimental and Clinical Research, Charité, Campus Berlin Buch, Klinik für Psychiatrie und Psychotherapie, Charité, Campus Berlin Mitte.
Michael
M
Colla
4 Rheinhessen Fachklinik Mainz, Kinder- und Jugendpsychiatrie, Mainz.
Michael
M
Huss
5 Städtisches Krankenhaus Dresden Neustadt, Zentrum für Kinder- und Jugendmedizin, Sozialpädiatrisches Zentrum.
Christoph
C
Kretschmar
6 Medizinische Abteilung Novartis Pharma GmbH, Nürnberg.
Marc
M
Brinkman
7 Rheinhessen Fachklinik Mainz, Zentrum für Kinderneurologie und Sozialpädiatrie.
Helmut
H
Peters
8 Berliner Behandlungszentrum der Abteilung für Psychiatrie, Psychotherapie und Psychosomatik, Evangelisches Krankenhaus Königin Elisabeth Herzberge GmbH, Berlin.
Samuel
S
Elstner
1 Klinik für Psychiatrie, Neurologie, Psychosomatik und Psychotherapie im Kindes- und Jugendalter der Universitätsmedizin Rostock.
Steffen
S
Weirich
9 Institut für Klinische Pharmakologie. Medizinische Fakultät, Technische Universität Carl Gustav Carus Dresden.
David
D
Pittrow
D000293:Adolescent; D002648:Child; D003131:Combined Modality Therapy; D015897:Comorbidity; D017281:Cost of Illness; D000066498:Emotional Adjustment; D056348:Emotional Intelligence; D005260:Female; D005600:Fragile X Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D005858:Germany; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D009460:Neurologic Examination; D010865:Pilot Projects; D011446:Prospective Studies; D012307:Risk Factors
EXPLAIN registry study; children and adolescents; fragile X syndrome; psychiatric symptoms; therapy