[The clinical characteristics surgical procedures and prognosis of solid pseudopapillary tumor of the pancreas].
Objective:To explore the clinical characteristics, surgical procedures and prognosis of solid pseudopapillary tumor of the pancreas(SPTP).Methods:The clinical and follow-up data of 55 cases with SPTP in Henan Tumor Hospital from June 2005 to April 2015 were retrospectively analyzed.Results:There were 55 SPTP cases, including 7 males and 48 females. The age ranged from 16 to 76 (median, 33). Clinical presentations of SPTP were not specific. The mean size of the tumor was 7.6 cm (range from 2 to 25cm). Pancreatic head and tail were the most common locations of SPTP. All the patients received surgical resection with a definitive pathological diagnosis. Some immunohistochemical markers were mostly positive, including β-catenin, Vim, Syn, CD10, CD56, PR, etc. With a median follow-up of 53 months, the 1-year, 2-year and 5-year survival rate were 98.1%, 96.1% and 94.0%, respectively.Conclusions:SPTP is an uncommon exocrine pancreatic neoplasm with low malignant potential, which frequently occurs in young women. Preoperative imaging can provide evidence for the selection of treatment modalities among which surgical resection ispreferred. Diagnosis still relies on pathology and immunohistochemistry.
Department of Gastroenterology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450000, China.
H
H
Yang
Department of Gastroenterology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450000, China.
N
N
Li
Department of Gastroenterology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450000, China.
W Y
WY
Deng
Department of Gastroenterology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450000, China.
S X
SX
Luo
D000293:Adolescent; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D002291:Carcinoma, Papillary / Q000737:chemistry / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000737:chemistry / Q000473:pathology / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000737:chemistry / Q000401:mortality / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D047368:Tumor Burden
D014408:Biomarkers, Tumor
Clinical characteristics; Pancreatic neoplasms; Prognosis; Solid pseudopapillary tumor of the pancreas, SPTP; Surgical procedures