Magnetic Solid-Phase Extraction of N,N-Diethyl-m-Toluamide From Baby Toilet Water Prior to its HPLC-UV Detection.
Fe3O4@MIL-100 (MIL, Material Institut Lavoisier) core-shell magnetic microspheres were prepared and applied as the sorbent for the magnetic solid phase extraction (MSPE) of N,N-diethyl-m-toluamide (DEET) in baby toilet water for the first time. The synthesized magnetic metal-organic frameworks were characterized by transmission electron microscope, infrared spectroscopy and thermogravimetric analysis. The functionalized magnetic microparticles showed excellent dispersibility in aqueous solution. The MSPE conditions were investigated in detail. Under the optimized conditions, an MSPE-high performance liquid chromatography method for the determination of DEET was developed. The method was linear in the concentration range from 5 to 500 μg L-1 for DEET in baby toilet water and good linearity (r2 > 0.9998) was obtained for the calibration curve. The limit of detection was 1.5 μg L-1. Both the intra-day and inter-day precisions (relative standard deviations) were <3%.
Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, No. 368 Youyi Road, Wuhan 430062, P. R. China.
Xiaowei
X
Ma
Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, No. 368 Youyi Road, Wuhan 430062, P. R. China.
Fan
F
Feng
Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, No. 368 Youyi Road, Wuhan 430062, P. R. China.
Yang
Y
Yang
Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, No. 368 Youyi Road, Wuhan 430062, P. R. China.
Xueping
X
Dang
Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, No. 368 Youyi Road, Wuhan 430062, P. R. China.
Jianlin
J
Huang
Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, No. 368 Youyi Road, Wuhan 430062, P. R. China.
Huaixia
H
Chen
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003671:DEET / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D057230:Limit of Detection; D016014:Linear Models; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D009994:Osmolar Concentration; D015203:Reproducibility of Results; D052616:Solid Phase Extraction / Q000379:methods*; D014867:Water / Q000032:analysis / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*
D058185:Magnetite Nanoparticles; D014874:Water Pollutants, Chemical; D014867:Water; D003671:DEET