An Extrapericardial Minimally Invasive Approach for Implantable Cardioverter Defibrillator.
The indications for placement of an implantable cardioverter defibrillators (ICDs) have greatly expanded over the last years. However, standard transvenous approach is not suitable for a subset of patients who cannot benefit from ICD therapy. Here, we have demonstrated the feasibility and efficacy of extrapericardial ICD placement through a minimally invasive access in intact hearts as well as in postmyocardial infarction large animal models. Based on our data, we conclude that extrapericardial ICD placement is a feasible approach that may be a valuable alternative or adjunct to current defibrillator lead systems.
Department of Cardiothoracic Surgery, Sanger Heart and Vascular Institute, Charlotte, North Carolina, United States.
Jeko M
JM
Madjarov
Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States.
Michael G
MG
Katz
Department of Cardiothoracic Surgery, Sanger Heart and Vascular Institute, Charlotte, North Carolina, United States.
Brad
B
Poole
Department of Cardiothoracic Surgery, Sanger Heart and Vascular Institute, Charlotte, North Carolina, United States.
Svetozar
S
Madzharov
Department of Cardiothoracic Surgery, Sanger Heart and Vascular Institute, Charlotte, North Carolina, United States.
John M
JM
Fedor
Department of Cardiothoracic Surgery, Sanger Heart and Vascular Institute, Charlotte, North Carolina, United States.
Francis
F
Robicsek
D000818:Animals; D017147:Defibrillators, Implantable; D004195:Disease Models, Animal; D004554:Electric Countershock / Q000295:instrumentation*; D004562:Electrocardiography; D005240:Feasibility Studies; D005260:Female; D009203:Myocardial Infarction / Q000150:complications; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000379:methods*; D034421:Sus scrofa; D014693:Ventricular Fibrillation / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*