Antimicrobial effect of the Biotronic® Top3 supplement and efficacy in protecting rainbow trout (Oncorhynchus mykiss) from infection by Aeromonas salmonicida subsp. salmonicida.
Demand for more environmentally friendly practices have led to the adoption of several feed supplements by the fish farming industry. In the present study, we investigated a commercially available formula that includes a mixture of three compounds: organic acids, a phytochemical and Biomin® Permeabilizing Complex. This mixture demonstrated antimicrobial properties in vitro and was able to inhibit growth of multiple species of aquatic bacterial pathogens, including Aeromonas salmonicida. Bacterial challenge was performed using A. salmonicida and three exposure routes: intra-peritoneal injection, immersion, and cohabitation. Mortality rates following infection by injection were significantly decreased in the fish that had received the supplemented feed. Fish infected through the other routes did not show a significant difference in mortality. In term of farming performance, while the fish that had received the feed supplement showed an improvement in weight gain and final weight, these changes were not found to be statistically significant. Similarly, no significant difference was observed in the feed conversion ratio. The results of this study suggest that this feed supplement may be effective at protecting rainbow trout from fish furunculosis.
Clinical Division of Fish Medicine, University of Veterinary Medicine, Vienna, Austria. Electronic address: Ledouble@vetmeduni.ac.at.
Simon
S
Menanteau-Ledouble
Clinical Division of Fish Medicine, University of Veterinary Medicine, Vienna, Austria.
Ines
I
Krauss
BIOMIN Holding GmbH, Erber Campus 1, 3131 Getzersdorf, Austria.
Rui Alexandre
RA
Goncalves
BIOMIN Research Center, Technopark 1, 3430 Tulln, Austria.
Barbara
B
Weber
BIOMIN Holding GmbH, Erber Campus 1, 3131 Getzersdorf, Austria.
Gonçalo Abreu
GA
Santos
Clinical Division of Fish Medicine, University of Veterinary Medicine, Vienna, Austria.
Mansour
M
El-Matbouli
D016980:Aeromonas hydrophila; D048409:Aeromonas salmonicida; D000821:Animal Feed / Q000032:analysis; D000818:Animals; D000900:Anti-Bacterial Agents; D017756:Aquaculture; D061046:Biological Control Agents; D004032:Diet; D019587:Dietary Supplements; D005393:Fish Diseases / Q000382:microbiology / Q000517:prevention & control*; D005503:Food Additives; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D017686:Oncorhynchus mykiss / Q000382:microbiology
D000900:Anti-Bacterial Agents; D061046:Biological Control Agents; D005503:Food Additives
Aeromonas salmonicida; Cinnamaldehyde; Feed supplement; Organic acids; Permeabilizer; Rainbow trout