[Choroidal metastasis from a lung adenocarcinoma treated by intravitreal injection of anti-VEGF and external beam radiotherapy: A case report].
Choroidal metastases of lung cancer are very uncommon. This localization should be suspected on blurred vision and confirmed with an ophthalmological examination. Its treatment is not entirely codified. We report a case of blurred vision secondary to bilateral choroidal metastasis in a patient with choroidal metastases from a lung adenocarcinoma, treated by intravitreal anti-vascular endothelial growth factor (VEGF) injection and external beam radiotherapy. According to a literature review, we analyzed the place of the targeted treatments used alone or combined with the radiotherapy.
Département universitaire de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, BP 42, 67065 Strasbourg cedex, France.
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I
Menoux
Département universitaire de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, BP 42, 67065 Strasbourg cedex, France.
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Guihard
Département universitaire de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, BP 42, 67065 Strasbourg cedex, France; Fédération de médecine translationnelle de Strasbourg (FMTS), laboratoire de radiobiologie, EA 3430, université de Strasbourg, 67065 Strasbourg, France.
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Antoni
Cabinet d'ophtalmologie, 7 bis, rue de l'Hôpital, 67600 Sélestat, France.
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Bijon
Département universitaire de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, BP 42, 67065 Strasbourg cedex, France; Fédération de médecine translationnelle de Strasbourg (FMTS), laboratoire de radiobiologie, EA 3430, université de Strasbourg, 67065 Strasbourg, France. Electronic address: gnoel@strasbourg.unicancer.fr.
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Noël
D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy*; D002830:Choroid Neoplasms / Q000556:secondary* / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D058449:Intravitreal Injections; D008175:Lung Neoplasms / Q000473:pathology*; D008875:Middle Aged; D011878:Radiotherapy / Q000379:methods; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors*
D042461:Vascular Endothelial Growth Factor A
Anti-VEGF; Carcinome non à petites cellules pulmonaire; Choroidal metastasis; Métastases choroïdiennes; NSCLC; Non-small cell lung cancer; Radiotherapy; Radiothérapie