Interaction of homeopathic potencies with the water soluble solvatochromic dye bis-dimethylaminofuchsone. Part 1: pH studies.
BACKGROUND
Previous studies have demonstrated the potential of solvatochromic dyes for investigating the physical chemistry of homeopathic potencies.


RESULTS
Following examination of this class of dyes in organic solvents, results obtained using the positively solvatochromic dye Bis-dimethylaminofuchsone (BDF) in aqueous solution are now reported. Spectral changes observed with this dye in the presence of potencies are both substantial and reproducible. Studies across a wide range of pH values reveal an unusual pH dependence for the dye's interaction with homeopathic potencies. Results indicate potency enhances dye protonation at pH values below c. 7.0, whilst protecting the dye from attack by hydroxyl ions above c. pH 7.5.


CONCLUSIONS
A possible explanation for these observations is offered in terms of a potency - induced electron density shift in BDF. The interaction of homeopathic potencies with solvatochromic dyes, particularly BDF, points towards a possible physico-chemical model for the nature of potencies, how they may be interacting with this class of dyes, and moreover how their biological effects may be mediated.
DiagnOx Laboratory, Cherwell Innovation Centre, Upper Heyford, Oxon, OX25 5HD, UK. Electronic address: steven.cartwright@oxford-homeopathy.org.uk.
Steven J
SJ
Cartwright
D004396:Coloring Agents / Q000737:chemistry*; D006705:Homeopathy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012394:Rosaniline Dyes / Q000737:chemistry*
D004396:Coloring Agents; D012394:Rosaniline Dyes
Bis-dimethylaminofuchsone; Excited state; Homeopathic potencies; Solvatochromism; Water solubility; pH; pKa values