Cross-Regulation between Transposable Elements and Host DNA Replication.
Transposable elements subvert host cellular functions to ensure their survival. Their interaction with the host DNA replication machinery indicates that selective pressures lead them to develop ancestral and convergent evolutionary adaptations aimed at conserved features of this fundamental process. These interactions can shape the co-evolution of the transposons and their hosts.
Department of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey, 604 Allison Rd, Nelson Biolabs A133, Piscataway, NJ 08854, USA. zaratiegui@dls.rutgers.edu.
Mikel
M
Zaratiegui
D005075:Biological Evolution; D004261:DNA Replication; D004251:DNA Transposable Elements; D005786:Gene Expression Regulation; D006801:Humans
D004251:DNA Transposable Elements
DNA replication; genome integrity; replication fork; transcription; transposable elements