[Intra-uterine insemination at either 24 or 48hours after ovulation induction: Pregnancy and birth rates].
OBJECTIVE
Comparing rates of pregnancy and childbirth between IUI at either 24 or 48hours after injection of HCG.


METHODS
This is a single-center retrospective study of couples who underwent intrauterine insemination between January 2013 and December 2014 at Medical-Surgical Obstetrical Centre of Schiltigheim. Stimulation of ovulation was done by FSH or HMG, and ovulation induction by 250μg of recombinant HCG. The insemination was performed after 2 days (group D2) or the day after (group D1).


RESULTS
Among the 1092 intrauterine insemination cycles included in our study, 62 were done the day after ovulation induction by HCG (D1), and 1030 the day after (D2). Our study showed no significant difference in the rate of biological pregnancy, defined by a rate of BHCG>15IU/L, between the group D1 (19.35%) and the group D2 (18.12%), P=0.94, and no difference in live birth rate: respectively 14,50% and 11.75%, P=0.18.


CONCLUSIONS
Our study reported similar rates of pregnancy and childbirth in the group who underwent IUI at D1 and D2 of ovulation induction, suggesting the possibility of IUI on day 1 when the organization of the service needs it, without loss of opportunity for pregnancy.
Centre médico-chirurgical obstétrical (CMCO), 19, rue Louis-Pasteur, 67300 Schiltigheim, France. Electronic address: Laure.hal@hotmail.com.
L
L
Haller
Service de santé publique, hôpital Civil, 1, place de l'Hôpital, BP n(o) 426, 67091 Strasbourg, France.
F
F
Severac
Centre médico-chirurgical obstétrical (CMCO), 19, rue Louis-Pasteur, 67300 Schiltigheim, France.
C
C
Rongieres
Centre médico-chirurgical obstétrical (CMCO), 19, rue Louis-Pasteur, 67300 Schiltigheim, France.
J
J
Ohl
Centre médico-chirurgical obstétrical (CMCO), 19, rue Louis-Pasteur, 67300 Schiltigheim, France.
K
K
Bettahar
Centre médico-chirurgical obstétrical (CMCO), 19, rue Louis-Pasteur, 67300 Schiltigheim, France.
I
I
Lichtblau
Centre médico-chirurgical obstétrical (CMCO), 19, rue Louis-Pasteur, 67300 Schiltigheim, France.
O
O
Pirrello
D000328:Adult; D001723:Birth Rate; D006063:Chorionic Gonadotropin / Q000008:administration & dosage; D005260:Female; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D008596:Menotropins / Q000008:administration & dosage; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D012189:Retrospective Studies; D013997:Time Factors
D006063:Chorionic Gonadotropin; D008596:Menotropins; D005640:Follicle Stimulating Hormone
AMP; Accouchement; Assisted reproductive technic; Childbirth; Grossesse; Insémination intra-utérine; Intrauterine insemination; Pregnancy