Speculative Considerations about Some Cardiology Enigmas.
BACKGROUND
Enigmas often lead to hypotheses and speculations. For this reason, especially for the sake of the reader's motivation, we opted for the plain discussion of some cardiology enigmas.


OBJECTIVE
The present text was aimed to discuss speculatively some cardiology enigmas.


METHODS
Text was freely designed in the context of coronary artery and heart valve diseases.


RESULTS
The results were presented as the combination enigma/hypothesis. 1) The absence of arteriosclerosis in intramyocardial coronary arteries/ endothelium-myocardial interaction (crosstalk); 2) The unique and always confirmed superior evolution of the internal thoracic artery as coronary graft/ higher NO basal release 3) The prophylactic left internal thoracic artery graft in mildlystenosed coronary lesions/need of more accurate functional imaging techniques; 4) The high incidence of perioperative atrial fibrillation in patients with coronary artery disease/atrial ischemia associated to left circumflex coronary lesions; 5) The handling of disease-free saphenous vein grafts at the time of reoperation/biological serendipity with graft vein segments; 6) The possible aortic stenosis protection against coronary artery disease/ endothelium-myocardium interaction (crosstalk) improving NO release.


CONCLUSIONS
The discussed topics associated with their respective speculative hypothesis remain as enigmas, but would become motivations for investigations.
Department of Surgery and Anatomy, Ribeirão Preto School of Medicine, University of São Paulo, Av. Bandeirantes, 3900 - Monte Alegre - CEP: 14049-900 Ribeirão Preto/SP. Brazil.
Paulo Roberto Barbosa
PRB
Evora
Department of Surgery and Anatomy (Division of Cardiothoracic Surgery); Department of Medicine (Division of Cardiology); Ribeirão Preto School of Medicine, University of São Paulo, SP. Brazil.
Andre
A
Schmidt
Department of Surgery and Anatomy (Division of Cardiothoracic Surgery); Department of Medicine (Division of Cardiology); Ribeirão Preto School of Medicine, University of São Paulo, SP. Brazil.
Livia
L
Arcêncio
Department of Surgery and Anatomy (Division of Cardiothoracic Surgery); Department of Medicine (Division of Cardiology); Ribeirão Preto School of Medicine, University of São Paulo, SP. Brazil.
José Antonio
JA
Marin-Neto
D002309:Cardiology; D001026:Coronary Artery Bypass / Q000379:methods*; D003324:Coronary Artery Disease / Q000601:surgery*; D006801:Humans
Coronary artery disease; arteriosclerosis; atrial fibrillation; cardiology enigmas; controversies; heart valve disease