[Clinical observation on the treatment of untreatable childhood glaucoma with microcatheter-assisted trabeculotomy].
Objective:To evaluate the efficacy of microcatheter-assisted trabeculotomy for untreatable childhood glaucoma with traditional surgeries repeatedly.Methods:Clinical charts of fifteen cases (16 eyes) with childhood glaucoma patients from Beijing Tongren Hospital were retrospectively analyzed. All eyes had previously received 2 or more traditional anti-glaucoma surgeries. We performed microcatheter-assisted trabeculotomy for these patients. The intraocular pressure (IOP), numbers of anti-glaucoma medications and post-operative complications were analyzed. The differences between pre-operative and last post-operative IOP and numbers of anti-glaucoma medications were compared using pariedttest and wilcoxon signed rank test.Results:Thirteen male and 2 female children aged between 2-10 (median: 4) years old were recruited. 11 cases (12 eyes) were diagnosed as primary congenital glaucoma, 3 eyes of 3 cases were late-onset childhood glaucoma, and 1 eye was secondary glaucoma. The mean pre-operative IOP was (35.69 ± 6.27) mmHg (1 mmHg=0.133 kPa) on a mean of 3(1-4) medications for childhood glaucoma patients. The mean post-operative IOP decreased to (17.88 ± 7.74) mmHg (t=6.97,P< 0.01) and the median post operative medications decreased to 0(0-3)(Z=-3.15,P<0.01) at last visit. Twelve cases and 14 cases achieved complete and qualified success, respectively. No severe complications were observed for all patients.Conclusion:Microcatheter-assisted trabeculotomy got lower introcular pressure results for 15 childhood glaucoma patients with untreadtable traditional surgeries repeatedly with minimal complications. (Chin J Ophthalmol,2017,53:203-206).
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab., Beijing 100730, China.
H Z
HZ
Wang
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Li
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M
Hu
Y W
YW
Wang
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Y
Shi
W W
WW
Wang
N L
NL
Wang
D002404:Catheterization / Q000295:instrumentation*; D002648:Child; D005260:Female; D005901:Glaucoma / Q000151:congenital / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D009901:Optic Nerve Diseases; D011183:Postoperative Complications; D011184:Postoperative Period; D012086:Reoperation; D012162:Retinal Degeneration; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome
Catheterization; Child; Glaucoma; Intraocular pressure; Trabecular meshwork; Trabeculotomy