Clinical application of calculated split renal volume using computed tomography-based renal volumetry after partial nephrectomy: Correlation with technetium-99m dimercaptosuccinic acid renal scan data.
To evaluate the clinical application of computed tomography-based measurement of renal cortical volume and split renal volume as a single tool to assess the anatomy and renal function in patients with renal tumors before and after partial nephrectomy, and to compare the findings with technetium-99m dimercaptosuccinic acid renal scan.



The data of 51 patients with a unilateral renal tumor managed by partial nephrectomy were retrospectively analyzed. The renal cortical volume of tumor-bearing and contralateral kidneys was measured using ImageJ software. Split estimated glomerular filtration rate and split renal volume calculated using this renal cortical volume were compared with the split renal function measured with technetium-99m dimercaptosuccinic acid renal scan.



A strong correlation between split renal function and split renal volume of the tumor-bearing kidney was observed before and after surgery (r = 0.89, P < 0.001 and r = 0.94, P < 0.001). The preoperative and postoperative split estimated glomerular filtration rate of the operated kidney showed a moderate correlation with split renal function (r = 0.39, P = 0.004 and r = 0.49, P < 0.001). The correlation between reductions in split renal function and split renal volume of the operated kidney (r = 0.87, P < 0.001) was stronger than that between split renal function and percent reduction in split estimated glomerular filtration rate (r = 0.64, P < 0.001).



The split renal volume calculated using computed tomography-based renal volumetry had a strong correlation with the split renal function measured using technetium-99m dimercaptosuccinic acid renal scan. Computed tomography-based split renal volume measurement before and after partial nephrectomy can be used as a single modality for anatomical and functional assessment of the tumor-bearing kidney.
Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.|Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Chan Ho
CH
Lee
Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Young Joo
YJ
Park
Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Ja Yoon
JY
Ku
Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.|Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Hong Koo
HK
Ha
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007672:Kidney Cortex / Q000033:anatomy & histology / Q000000981:diagnostic imaging* / Q000502:physiology; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods; D009929:Organ Size; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D012189:Retrospective Studies; D012984:Software; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D014057:Tomography, X-Ray Computed / Q000379:methods*
D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
computed tomography volumetry; partial nephrectomy; renal tumor; split renal function