Receptor-interacting protein kinase 3 controls keratinocyte activation in a necroptosis-independent manner and promotes psoriatic dermatitis in mice.
Center for Innovation in Immunoregulative Technology and Therapeutics, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address: hontetsu@kuhp.kyoto-u.ac.jp.
Tetsuya
T
Honda
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Tottori University Faculty of Medicine, Tottori, Japan.
Osamu
O
Yamamoto
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan.
Yu
Y
Sawada
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Gyohei
G
Egawa
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Akihiko
A
Kitoh
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Atsushi
A
Otsuka
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Teruki
T
Dainichi
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Saeko
S
Nakajima
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yoshiki
Y
Miyachi
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan. Electronic address: kaba@kuhp.kyoto-u.ac.jp.
Kenji
K
Kabashima
D000818:Animals; D017209:Apoptosis / Q000235:genetics*; D015415:Biomarkers; D004195:Disease Models, Animal; D007150:Immunohistochemistry; D015603:Keratinocytes / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D018345:Mice, Knockout; D009336:Necrosis / Q000235:genetics* / Q000378:metabolism; D020556:Neutrophil Infiltration; D011565:Psoriasis / Q000235:genetics* / Q000378:metabolism / Q000473:pathology*; D053422:Receptor-Interacting Protein Serine-Threonine Kinases / Q000235:genetics* / Q000378:metabolism
D015415:Biomarkers; D053422:Receptor-Interacting Protein Serine-Threonine Kinases; C485615:Ripk3 protein, mouse