Allergenic Ingredients in Personal Hygiene Wet Wipes.
BACKGROUND
Wet wipes are a significant allergen source for anogenital allergic contact dermatitis.


OBJECTIVE
The aim of the study was to calculate the frequency of potentially allergenic ingredients in personal hygiene wet wipes.


METHODS
Ingredient lists from brand name and generic personal hygiene wet wipes from 4 large retailers were compiled.


RESULTS
In the 54 personal hygiene wet wipes evaluated, a total of 132 ingredients were identified (average of 11.9 ingredients per wipe). The most common ingredients were Aloe barbadensis (77.8%), citric acid (77.8%), fragrance (72.2%), sorbic acid derivatives (63.0%), tocopherol derivatives (63.0%), glycerin (59.3%), phenoxyethanol (55.6%), disodium cocoamphodiacetate (53.7%), disodium ethylenediaminetetraacetic acid (EDTA) (42.6%), propylene glycol (42.6%), iodopropynyl butylcarbamate (40.7%), chamomile extracts (38.9%), sodium benzoate (35.2%), bronopol (22.2%), sodium citrate (22.2%), lanolin derivatives (20.4%), parabens (20.4%), polyethylene glycol derivatives (18.5%), disodium phosphate (16.7%), dimethylol dimethyl hydantoin (DMDM) (14.8%), and cocamidopropyl propylene glycol (PG)-dimonium chloride phosphate (11.1%). Of note, methylisothiazolinone (5.6%) was uncommon; methylchloroisothiazolinone was not identified in the personal hygiene wet wipes examined.


CONCLUSIONS
There are many potential allergens in personal hygiene wet wipes, especially fragrance and preservatives.
From the *University of Minnesota School of Medicine; †Department of Dermatology, Minneapolis Veterans Affairs Medical Center; ‡HCMC Parkside Occupational and Contact Dermatitis Clinic; and §Department of Dermatology, University of Minnesota, Minneapolis.
Kelly A
KA
Aschenbeck
Erin M
EM
Warshaw
D000485:Allergens / Q000009:adverse effects / Q000032:analysis*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D006795:Household Products / Q000009:adverse effects*; D006801:Humans; D006920:Hygiene; D010328:Patch Tests; D014481:United States
D000485:Allergens