Adding Recognition Discriminability Index to the Delayed Recall Is Useful to Predict Conversion from Mild Cognitive Impairment to Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative.
Background:Ongoing research is focusing on the identification of those individuals with mild cognitive impairment (MCI) who are most likely to convert to Alzheimer's disease (AD). We investigated whether recognition memory tasks in combination with delayed recall measure of episodic memory and CSF biomarkers can predict MCI to AD conversion at 24-month follow-up.Methods:A total of 397 amnestic-MCI subjects from Alzheimer's disease Neuroimaging Initiative were included. Logistic regression modeling was done to assess the predictive value of all RAVLT measures, risk factors such as age, sex, education, APOE genotype, and CSF biomarkers for progression to AD. Estimating adjusted odds ratios was used to determine which variables would produce an optimal predictive model, and whether adding tests of interaction between the RAVLT Delayed Recall and recognition measures (traditional score and d-prime) would improve prediction of the conversion from a-MCI to AD.Results:112 (28.2%) subjects developed dementia and 285 (71.8%) subjects did not. Of the all included variables, CSF Aβ1-42 levels, RAVLT Delayed Recall, and the combination of RAVLT Delayed Recall and d-prime were predictive of progression to AD (χ2= 38.23,df= 14,p< 0.001).Conclusions:The combination of RAVLT Delayed Recall and d-prime measures may be predictor of conversion from MCI to AD in the ADNI cohort, especially in combination with amyloid biomarkers. A predictive model to help identify individuals at-risk for dementia should include not only traditional episodic memory measures (delayed recall or recognition), but also additional variables (d-prime) that allow the homogenization of the assessment procedures in the diagnosis of MCI.
Author Affiliations: UC San Francisco; University of Southern California; UC San Francisco University of Southern California Mayo Clinic, Rochester Mayo Clinic, Rochester; UC Berkeley; U Pennsylvania; USC; UC Davis; Brigham and Women's Hospital/Harvard Medical School Indiana University Washington University St. Louis University of Pennsylvania; Prevent Alzheimer's Disease 2020 (Chair) Siemens; Alzheimer's Association University of Pittsburgh Washington University St. Louis Cornell University; Albert Einstein College of Medicine of Yeshiva University; AD Drug Discovery Foundation; Acumen Pharmaceuticals; Washington University St. Louis; Northwestern University; National Institute of Mental Health; Brown University; Eli Lilly (Chair); BWH/HMS (Chair); University of Washington (Chair); Mayo Clinic, Rochester (Core PI) University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC Davis (Core PI); UC Davis; UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; University of London; UCLA School of Medicine; UCSF MRI; UC Davis; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; University of Pittsburgh; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; UC San Diego; Prevent Alzheimer's Disease 2020; UC San Diego; National Institute on Aging; UC San Francisco; Brown University; National Institute of Mental Health; Cornell University; Johns Hopkins University; Richard Frank Consulting; Prevent Alzheimer's Disease 2020; National Institute on Aging; Oregon Health & Science University; University of Southern California; University of California - San Diego; University of Michigan; Mayo Clinic, Rochester; Baylor College of Medicine; Columbia University Medical Center; Washington University, St. Louis; University of Alabama - Birmingham; Mount Sinai School of Medicine; Rush University Medical Center; Wien Center; Johns Hopkins University; New York University; Duke University Medical Center; University of Pennsylvania; University of Kentucky; University of Pittsburgh; University of Rochester Medical Center; University of California, Irvine; University of Texas Southwestern Medical School; Emory University; University of Kansas, Medical Center; University of California, Los Angeles; Mayo Clinic, Jacksonville; Indiana University; Yale University School of Medicine; McGill Univ., Montreal-Jewish General Hospital; Sunnybrook Health Sciences, Ontario; U.B.C. Clinic for AD & Related Disorders; Cognitive Neurology - St. Joseph's, Ontario; Cleveland Clinic Lou Ruvo Center for Brain Health; Northwestern University; Premiere Research Inst (Palm Beach Neurology); Georgetown University Medical Center; Brigham and Women's Hospital; Stanford University; Banner Sun Health Research Institute; Boston University; Howard University; Case Western Reserve University; University of California, Davis - Sacramento; Neurological Care of CNY; Parkwood Hospital; University of Wisconsin; University of California, Irvine - BIC; Banner Alzheimer's Institute; Dent Neurologic Institute; Ohio State University; Albany Medical College; Hartford Hospital, Olin Neuropsychiatry Research Center; Dartmouth-Hitchcock Medical Center; Wake Forest University Health Sciences; Rhode Island Hospital; Butler Hospital; UC San Francisco; Medical University South Carolina; St. Joseph's Health Care; Nathan Kline Institute; University of Iowa College of Medicine; Cornell University; University of South Florida: USF Health Byrd Alzheimer's Institute; University of California, San Francisco; University of Southern California; UC San Francisco; University of Southern California; Mayo Clinic, Rochester; Brigham and Women's Hospital/ Harvard Medical School; UC Davis; Mayo Clinic, Rochester; UC Berkeley; Washington University St. Louis; Indiana University; Perelman School of Medicine, UPenn; USC; Perelman School of Medicine, University of Pennsylvania; UC San Francisco; Rehabilitation Institute of Chicago, Feinberg School of Medicine, Northwestern University; BWH/HMS (Chair); University of Washington (Chair); Core PI; Mayo Clinic, Rochester (Core PI); University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Francisco; UC San Francisco; UC San Francisco; UC Davis (Core PI); UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; Department of Defense (retired); University of Southern California; University of California, San Diego; Columbia University Medical Center; Rush University Medical Center; Wien Center; Duke University Medical Center; University of Rochester Medical Center; University of California, Irvine; Medical University South Carolina; Premiere Research Inst (Palm Beach Neurology); University of California, San Francisco; Georgetown University Medical Center; Brigham and Women's Hospital; Banner Sun Health Research Institute; Howard University; University of Wisconsin; University of Washington; Stanford University; Cornell University.
María J
MJ
Russo
Author Affiliations: UC San Francisco; University of Southern California; UC San Francisco University of Southern California Mayo Clinic, Rochester Mayo Clinic, Rochester; UC Berkeley; U Pennsylvania; USC; UC Davis; Brigham and Women's Hospital/Harvard Medical School Indiana University Washington University St. Louis University of Pennsylvania; Prevent Alzheimer's Disease 2020 (Chair) Siemens; Alzheimer's Association University of Pittsburgh Washington University St. Louis Cornell University; Albert Einstein College of Medicine of Yeshiva University; AD Drug Discovery Foundation; Acumen Pharmaceuticals; Washington University St. Louis; Northwestern University; National Institute of Mental Health; Brown University; Eli Lilly (Chair); BWH/HMS (Chair); University of Washington (Chair); Mayo Clinic, Rochester (Core PI) University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC Davis (Core PI); UC Davis; UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; University of London; UCLA School of Medicine; UCSF MRI; UC Davis; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; University of Pittsburgh; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; UC San Diego; Prevent Alzheimer's Disease 2020; UC San Diego; National Institute on Aging; UC San Francisco; Brown University; National Institute of Mental Health; Cornell University; Johns Hopkins University; Richard Frank Consulting; Prevent Alzheimer's Disease 2020; National Institute on Aging; Oregon Health & Science University; University of Southern California; University of California - San Diego; University of Michigan; Mayo Clinic, Rochester; Baylor College of Medicine; Columbia University Medical Center; Washington University, St. Louis; University of Alabama - Birmingham; Mount Sinai School of Medicine; Rush University Medical Center; Wien Center; Johns Hopkins University; New York University; Duke University Medical Center; University of Pennsylvania; University of Kentucky; University of Pittsburgh; University of Rochester Medical Center; University of California, Irvine; University of Texas Southwestern Medical School; Emory University; University of Kansas, Medical Center; University of California, Los Angeles; Mayo Clinic, Jacksonville; Indiana University; Yale University School of Medicine; McGill Univ., Montreal-Jewish General Hospital; Sunnybrook Health Sciences, Ontario; U.B.C. Clinic for AD & Related Disorders; Cognitive Neurology - St. Joseph's, Ontario; Cleveland Clinic Lou Ruvo Center for Brain Health; Northwestern University; Premiere Research Inst (Palm Beach Neurology); Georgetown University Medical Center; Brigham and Women's Hospital; Stanford University; Banner Sun Health Research Institute; Boston University; Howard University; Case Western Reserve University; University of California, Davis - Sacramento; Neurological Care of CNY; Parkwood Hospital; University of Wisconsin; University of California, Irvine - BIC; Banner Alzheimer's Institute; Dent Neurologic Institute; Ohio State University; Albany Medical College; Hartford Hospital, Olin Neuropsychiatry Research Center; Dartmouth-Hitchcock Medical Center; Wake Forest University Health Sciences; Rhode Island Hospital; Butler Hospital; UC San Francisco; Medical University South Carolina; St. Joseph's Health Care; Nathan Kline Institute; University of Iowa College of Medicine; Cornell University; University of South Florida: USF Health Byrd Alzheimer's Institute; University of California, San Francisco; University of Southern California; UC San Francisco; University of Southern California; Mayo Clinic, Rochester; Brigham and Women's Hospital/ Harvard Medical School; UC Davis; Mayo Clinic, Rochester; UC Berkeley; Washington University St. Louis; Indiana University; Perelman School of Medicine, UPenn; USC; Perelman School of Medicine, University of Pennsylvania; UC San Francisco; Rehabilitation Institute of Chicago, Feinberg School of Medicine, Northwestern University; BWH/HMS (Chair); University of Washington (Chair); Core PI; Mayo Clinic, Rochester (Core PI); University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Francisco; UC San Francisco; UC San Francisco; UC Davis (Core PI); UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; Department of Defense (retired); University of Southern California; University of California, San Diego; Columbia University Medical Center; Rush University Medical Center; Wien Center; Duke University Medical Center; University of Rochester Medical Center; University of California, Irvine; Medical University South Carolina; Premiere Research Inst (Palm Beach Neurology); University of California, San Francisco; Georgetown University Medical Center; Brigham and Women's Hospital; Banner Sun Health Research Institute; Howard University; University of Wisconsin; University of Washington; Stanford University; Cornell University.
Jorge
J
Campos
Author Affiliations: UC San Francisco; University of Southern California; UC San Francisco University of Southern California Mayo Clinic, Rochester Mayo Clinic, Rochester; UC Berkeley; U Pennsylvania; USC; UC Davis; Brigham and Women's Hospital/Harvard Medical School Indiana University Washington University St. Louis University of Pennsylvania; Prevent Alzheimer's Disease 2020 (Chair) Siemens; Alzheimer's Association University of Pittsburgh Washington University St. Louis Cornell University; Albert Einstein College of Medicine of Yeshiva University; AD Drug Discovery Foundation; Acumen Pharmaceuticals; Washington University St. Louis; Northwestern University; National Institute of Mental Health; Brown University; Eli Lilly (Chair); BWH/HMS (Chair); University of Washington (Chair); Mayo Clinic, Rochester (Core PI) University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC Davis (Core PI); UC Davis; UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; University of London; UCLA School of Medicine; UCSF MRI; UC Davis; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; University of Pittsburgh; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; UC San Diego; Prevent Alzheimer's Disease 2020; UC San Diego; National Institute on Aging; UC San Francisco; Brown University; National Institute of Mental Health; Cornell University; Johns Hopkins University; Richard Frank Consulting; Prevent Alzheimer's Disease 2020; National Institute on Aging; Oregon Health & Science University; University of Southern California; University of California - San Diego; University of Michigan; Mayo Clinic, Rochester; Baylor College of Medicine; Columbia University Medical Center; Washington University, St. Louis; University of Alabama - Birmingham; Mount Sinai School of Medicine; Rush University Medical Center; Wien Center; Johns Hopkins University; New York University; Duke University Medical Center; University of Pennsylvania; University of Kentucky; University of Pittsburgh; University of Rochester Medical Center; University of California, Irvine; University of Texas Southwestern Medical School; Emory University; University of Kansas, Medical Center; University of California, Los Angeles; Mayo Clinic, Jacksonville; Indiana University; Yale University School of Medicine; McGill Univ., Montreal-Jewish General Hospital; Sunnybrook Health Sciences, Ontario; U.B.C. Clinic for AD & Related Disorders; Cognitive Neurology - St. Joseph's, Ontario; Cleveland Clinic Lou Ruvo Center for Brain Health; Northwestern University; Premiere Research Inst (Palm Beach Neurology); Georgetown University Medical Center; Brigham and Women's Hospital; Stanford University; Banner Sun Health Research Institute; Boston University; Howard University; Case Western Reserve University; University of California, Davis - Sacramento; Neurological Care of CNY; Parkwood Hospital; University of Wisconsin; University of California, Irvine - BIC; Banner Alzheimer's Institute; Dent Neurologic Institute; Ohio State University; Albany Medical College; Hartford Hospital, Olin Neuropsychiatry Research Center; Dartmouth-Hitchcock Medical Center; Wake Forest University Health Sciences; Rhode Island Hospital; Butler Hospital; UC San Francisco; Medical University South Carolina; St. Joseph's Health Care; Nathan Kline Institute; University of Iowa College of Medicine; Cornell University; University of South Florida: USF Health Byrd Alzheimer's Institute; University of California, San Francisco; University of Southern California; UC San Francisco; University of Southern California; Mayo Clinic, Rochester; Brigham and Women's Hospital/ Harvard Medical School; UC Davis; Mayo Clinic, Rochester; UC Berkeley; Washington University St. Louis; Indiana University; Perelman School of Medicine, UPenn; USC; Perelman School of Medicine, University of Pennsylvania; UC San Francisco; Rehabilitation Institute of Chicago, Feinberg School of Medicine, Northwestern University; BWH/HMS (Chair); University of Washington (Chair); Core PI; Mayo Clinic, Rochester (Core PI); University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Francisco; UC San Francisco; UC San Francisco; UC Davis (Core PI); UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; Department of Defense (retired); University of Southern California; University of California, San Diego; Columbia University Medical Center; Rush University Medical Center; Wien Center; Duke University Medical Center; University of Rochester Medical Center; University of California, Irvine; Medical University South Carolina; Premiere Research Inst (Palm Beach Neurology); University of California, San Francisco; Georgetown University Medical Center; Brigham and Women's Hospital; Banner Sun Health Research Institute; Howard University; University of Wisconsin; University of Washington; Stanford University; Cornell University.
Silvia
S
Vázquez
Author Affiliations: UC San Francisco; University of Southern California; UC San Francisco University of Southern California Mayo Clinic, Rochester Mayo Clinic, Rochester; UC Berkeley; U Pennsylvania; USC; UC Davis; Brigham and Women's Hospital/Harvard Medical School Indiana University Washington University St. Louis University of Pennsylvania; Prevent Alzheimer's Disease 2020 (Chair) Siemens; Alzheimer's Association University of Pittsburgh Washington University St. Louis Cornell University; Albert Einstein College of Medicine of Yeshiva University; AD Drug Discovery Foundation; Acumen Pharmaceuticals; Washington University St. Louis; Northwestern University; National Institute of Mental Health; Brown University; Eli Lilly (Chair); BWH/HMS (Chair); University of Washington (Chair); Mayo Clinic, Rochester (Core PI) University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC Davis (Core PI); UC Davis; UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; University of London; UCLA School of Medicine; UCSF MRI; UC Davis; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; University of Pittsburgh; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; UC San Diego; Prevent Alzheimer's Disease 2020; UC San Diego; National Institute on Aging; UC San Francisco; Brown University; National Institute of Mental Health; Cornell University; Johns Hopkins University; Richard Frank Consulting; Prevent Alzheimer's Disease 2020; National Institute on Aging; Oregon Health & Science University; University of Southern California; University of California - San Diego; University of Michigan; Mayo Clinic, Rochester; Baylor College of Medicine; Columbia University Medical Center; Washington University, St. Louis; University of Alabama - Birmingham; Mount Sinai School of Medicine; Rush University Medical Center; Wien Center; Johns Hopkins University; New York University; Duke University Medical Center; University of Pennsylvania; University of Kentucky; University of Pittsburgh; University of Rochester Medical Center; University of California, Irvine; University of Texas Southwestern Medical School; Emory University; University of Kansas, Medical Center; University of California, Los Angeles; Mayo Clinic, Jacksonville; Indiana University; Yale University School of Medicine; McGill Univ., Montreal-Jewish General Hospital; Sunnybrook Health Sciences, Ontario; U.B.C. Clinic for AD & Related Disorders; Cognitive Neurology - St. Joseph's, Ontario; Cleveland Clinic Lou Ruvo Center for Brain Health; Northwestern University; Premiere Research Inst (Palm Beach Neurology); Georgetown University Medical Center; Brigham and Women's Hospital; Stanford University; Banner Sun Health Research Institute; Boston University; Howard University; Case Western Reserve University; University of California, Davis - Sacramento; Neurological Care of CNY; Parkwood Hospital; University of Wisconsin; University of California, Irvine - BIC; Banner Alzheimer's Institute; Dent Neurologic Institute; Ohio State University; Albany Medical College; Hartford Hospital, Olin Neuropsychiatry Research Center; Dartmouth-Hitchcock Medical Center; Wake Forest University Health Sciences; Rhode Island Hospital; Butler Hospital; UC San Francisco; Medical University South Carolina; St. Joseph's Health Care; Nathan Kline Institute; University of Iowa College of Medicine; Cornell University; University of South Florida: USF Health Byrd Alzheimer's Institute; University of California, San Francisco; University of Southern California; UC San Francisco; University of Southern California; Mayo Clinic, Rochester; Brigham and Women's Hospital/ Harvard Medical School; UC Davis; Mayo Clinic, Rochester; UC Berkeley; Washington University St. Louis; Indiana University; Perelman School of Medicine, UPenn; USC; Perelman School of Medicine, University of Pennsylvania; UC San Francisco; Rehabilitation Institute of Chicago, Feinberg School of Medicine, Northwestern University; BWH/HMS (Chair); University of Washington (Chair); Core PI; Mayo Clinic, Rochester (Core PI); University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Francisco; UC San Francisco; UC San Francisco; UC Davis (Core PI); UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; Department of Defense (retired); University of Southern California; University of California, San Diego; Columbia University Medical Center; Rush University Medical Center; Wien Center; Duke University Medical Center; University of Rochester Medical Center; University of California, Irvine; Medical University South Carolina; Premiere Research Inst (Palm Beach Neurology); University of California, San Francisco; Georgetown University Medical Center; Brigham and Women's Hospital; Banner Sun Health Research Institute; Howard University; University of Wisconsin; University of Washington; Stanford University; Cornell University.
Gustavo
G
Sevlever
Author Affiliations: UC San Francisco; University of Southern California; UC San Francisco University of Southern California Mayo Clinic, Rochester Mayo Clinic, Rochester; UC Berkeley; U Pennsylvania; USC; UC Davis; Brigham and Women's Hospital/Harvard Medical School Indiana University Washington University St. Louis University of Pennsylvania; Prevent Alzheimer's Disease 2020 (Chair) Siemens; Alzheimer's Association University of Pittsburgh Washington University St. Louis Cornell University; Albert Einstein College of Medicine of Yeshiva University; AD Drug Discovery Foundation; Acumen Pharmaceuticals; Washington University St. Louis; Northwestern University; National Institute of Mental Health; Brown University; Eli Lilly (Chair); BWH/HMS (Chair); University of Washington (Chair); Mayo Clinic, Rochester (Core PI) University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC Davis (Core PI); UC Davis; UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; University of London; UCLA School of Medicine; UCSF MRI; UC Davis; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; University of Pittsburgh; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; UPenn School of Medicine; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; UC San Diego; Prevent Alzheimer's Disease 2020; UC San Diego; National Institute on Aging; UC San Francisco; Brown University; National Institute of Mental Health; Cornell University; Johns Hopkins University; Richard Frank Consulting; Prevent Alzheimer's Disease 2020; National Institute on Aging; Oregon Health & Science University; University of Southern California; University of California - San Diego; University of Michigan; Mayo Clinic, Rochester; Baylor College of Medicine; Columbia University Medical Center; Washington University, St. Louis; University of Alabama - Birmingham; Mount Sinai School of Medicine; Rush University Medical Center; Wien Center; Johns Hopkins University; New York University; Duke University Medical Center; University of Pennsylvania; University of Kentucky; University of Pittsburgh; University of Rochester Medical Center; University of California, Irvine; University of Texas Southwestern Medical School; Emory University; University of Kansas, Medical Center; University of California, Los Angeles; Mayo Clinic, Jacksonville; Indiana University; Yale University School of Medicine; McGill Univ., Montreal-Jewish General Hospital; Sunnybrook Health Sciences, Ontario; U.B.C. Clinic for AD & Related Disorders; Cognitive Neurology - St. Joseph's, Ontario; Cleveland Clinic Lou Ruvo Center for Brain Health; Northwestern University; Premiere Research Inst (Palm Beach Neurology); Georgetown University Medical Center; Brigham and Women's Hospital; Stanford University; Banner Sun Health Research Institute; Boston University; Howard University; Case Western Reserve University; University of California, Davis - Sacramento; Neurological Care of CNY; Parkwood Hospital; University of Wisconsin; University of California, Irvine - BIC; Banner Alzheimer's Institute; Dent Neurologic Institute; Ohio State University; Albany Medical College; Hartford Hospital, Olin Neuropsychiatry Research Center; Dartmouth-Hitchcock Medical Center; Wake Forest University Health Sciences; Rhode Island Hospital; Butler Hospital; UC San Francisco; Medical University South Carolina; St. Joseph's Health Care; Nathan Kline Institute; University of Iowa College of Medicine; Cornell University; University of South Florida: USF Health Byrd Alzheimer's Institute; University of California, San Francisco; University of Southern California; UC San Francisco; University of Southern California; Mayo Clinic, Rochester; Brigham and Women's Hospital/ Harvard Medical School; UC Davis; Mayo Clinic, Rochester; UC Berkeley; Washington University St. Louis; Indiana University; Perelman School of Medicine, UPenn; USC; Perelman School of Medicine, University of Pennsylvania; UC San Francisco; Rehabilitation Institute of Chicago, Feinberg School of Medicine, Northwestern University; BWH/HMS (Chair); University of Washington (Chair); Core PI; Mayo Clinic, Rochester (Core PI); University of Southern California; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Diego; UC San Francisco; UC San Francisco; UC San Francisco; UC Davis (Core PI); UC San Diego; Mayo Clinic, Rochester (Core PI); Mayo Clinic, Rochester; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; UC Berkeley (Core PI); University of Michigan; University of Utah; Banner Alzheimer's Institute; Banner Alzheimer's Institute; UC Berkeley; Washington University St. Louis; Washington University St. Louis; Washington University St. Louis; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; Perelman School of Medicine, UPenn; USC (Core PI); USC; USC; Indiana University; Indiana University; UC Irvine; Indiana University; Indiana University; Indiana University; Indiana University; UC San Francisco; Department of Defense (retired); University of Southern California; University of California, San Diego; Columbia University Medical Center; Rush University Medical Center; Wien Center; Duke University Medical Center; University of Rochester Medical Center; University of California, Irvine; Medical University South Carolina; Premiere Research Inst (Palm Beach Neurology); University of California, San Francisco; Georgetown University Medical Center; Brigham and Women's Hospital; Banner Sun Health Research Institute; Howard University; University of Wisconsin; University of Washington; Stanford University; Cornell University.
Ricardo F
RF
Allegri
Alzheimer's disease; disease progression; memory; mild cognitive impairment; recognition discriminability; signal detection theory