Idiopathic scleredema.
Scleredema, which also is known as scleredemaadultorum of Buschke, is an uncommonsclerodermiform condition that is characterizedby progressive thickening and hardening of theskin due to excessive dermal mucin and collagendeposition. The clinical course is variable, andprogression of disease may lead to functionalimpairment with limitations in mobility. The etiologyand pathogenesis are unknown although severalwell-known associations include streptococcalinfection; diabetes mellitus, particularly withmetabolic syndrome; and monoclonal gammopathy.We present a case of scleredema in a 52-year-oldman with no identifiable associated condition,who experienced improvemement with UVBphototherapy.
Ronald O. Perelman Department of Dermatology, NYU School of Medicine, NYU Langone Medical Center.
Elise
E
Ng
Rachel
R
Rosenstein
Vitaly
V
Terushkin
Shane
S
Meehan
Miriam Keltz
MK
Pomeranz
D001415:Back; D006801:Humans; D008297:Male; D008875:Middle Aged; D012592:Scleredema Adultorum / Q000175:diagnosis* / Q000473:pathology