Complete genome sequence of Streptomyces griseochromogenes ATCC 14511T, a producer of nucleoside compounds and diverse secondary metabolites.
ATCC 14511T(=DSM 40499, =NBRC 13413) is a type strain of Streptomyces griseochromogenes. It is known as a producer of nucleoside antibiotic, blasticidin S. In this report we present the complete genome sequence of S. griseochromogenes ATCC 14511T, which consists of 10,764,674bp with a linear chromosome, 9822 protein-coding genes, 6 rRNA operons, 74 tRNA and 3 sRNA. The genomic analysis revealed that 52 putative gene clusters are involved in the biosynthesis of secondary metabolites, including four gene clusters of nucleoside antibiotics. These gene clusters provide a beneficial source for production of bioactive natural compounds.
State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou, China.
Lijuan
L
Wu
State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou, China.
Guoqing
G
Chen
State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou, China. Electronic address: fengguozhong@caas.cn.
Guozhong
G
Feng
D000935:Antifungal Agents / Q000378:metabolism* / Q000494:pharmacology; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D005658:Fungi / Q000187:drug effects; D016680:Genome, Bacterial / Q000235:genetics*; D005810:Multigene Family / Q000235:genetics; D009705:Nucleosides / Q000378:metabolism* / Q000494:pharmacology; D017422:Sequence Analysis, DNA; D013302:Streptomyces / Q000737:chemistry* / Q000145:classification / Q000235:genetics* / Q000378:metabolism
D000935:Antifungal Agents; D004269:DNA, Bacterial; D009705:Nucleosides
Arginomycin (PubChem CID:129552); Blasticidin S (PubChem CID:1675236); Gene cluster; Genome sequence; Nucleoside antibiotic; Streptomyces; Toyocamycin (PubChem CID:11824)