When self-assembly meets topology: an enhanced micelle stability.
The topology of hydrophobic moieties can affect the stability of self-assembled micelles. Curved corannulene and flat perylene were selected as model hydrophobic molecules with poly(ethylene glycol) as the hydrophilic segment. The curvature can enhance the intermolecular π-π interaction, and hence the driving force of micelle formation.
School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China. zhaoyj@tju.edu.cn wangzheng2006@tju.edu.cn.
Xiaopeng
X
Dong
School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China. zhaoyj@tju.edu.cn wangzheng2006@tju.edu.cn.
Xuliang
X
Guo
School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China. zhaoyj@tju.edu.cn wangzheng2006@tju.edu.cn.
Guangqin
G
Liu
School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China. zhaoyj@tju.edu.cn wangzheng2006@tju.edu.cn.
Aiping
A
Fan
School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China. zhaoyj@tju.edu.cn wangzheng2006@tju.edu.cn.
Zheng
Z
Wang
School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China. zhaoyj@tju.edu.cn wangzheng2006@tju.edu.cn.
Yanjun
http://orcid.org/0000-0001-5739-1960
Y
Zhao