Hair cortisol and dehydroepiandrosterone concentrations in naturally Taenia solium infected pigs in Tanzania.
The aim of this study was to measure hair cortisol and dehydroepiandrosterone (DHEA) concentrations in naturally Taenia solium infected and non-infected control pigs and assess the effect of an environmental change on the aforementioned parameters. Three hair patches were obtained from 13 T. solium infected and 15 non-infected controls sows, respectively corresponding to 3 time points (prior to, at and approximately two weeks after arrival at the research facility). Cortisol and DHEA were extracted using methanol and analysed by radio immune assay. Mean hair cortisol concentrations were significantly lower (p<0.001) in T. solium infected (4.7±3.0pg/mg) compared to control pigs (9.0±3.7pg/mg) prior to arrival at the research facility, however no significant difference was observed between the two groups at arrival and after approximately two weeks. Similar patterns were also observed for DHEA concentrations (infected pigs 253.9±82.3pg/mg, control pigs 387.7±116.4pg/mg) (p<0.001). Results showed that lean animals had significantly higher cortisol concentrations in both groups, infected and controls pigs, while DHEA was not significantly different between lean and normal animals. Results of this study have shown that an environmental change could have an effect on pigs' hormonal levels suggesting an undergoing adaptation process. After the pigs were kept under the same conditions, fed and watered ad libitum, no significant differences were observed between the groups, but a drop in DHEA concentrations was observed in all the pigs. Weight however had an effect on cortisol levels as lean animals had significantly higher cortisol concentrations in both groups, compared to normal pigs.
Department of Veterinary and Animal Sciences, University of Copenhagen, Dyrlægevej 100, 1870 Frederiksberg C, Denmark.
Chiara
C
Trevisan
Department of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Via Sondrio 2/A, 33100 Udine, Italy. Electronic address: marta.montillo@uniud.it.
Marta
M
Montillo
Department of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Via Sondrio 2/A, 33100 Udine, Italy.
Alberto
A
Prandi
Department of Veterinary Medicine and Public Health, Sokoine University of Agriculture, P.O. Box 3021, Morogoro, Tanzania.
Ernatus M
EM
Mkupasi
Department of Veterinary Medicine and Public Health, Sokoine University of Agriculture, P.O. Box 3021, Morogoro, Tanzania.
Helena A
HA
Ngowi
Department of Veterinary and Animal Sciences, University of Copenhagen, Dyrlægevej 100, 1870 Frederiksberg C, Denmark.
Maria V
MV
Johansen
D000818:Animals; D003687:Dehydroepiandrosterone / Q000378:metabolism*; D005260:Female; D006197:Hair / Q000737:chemistry*; D006854:Hydrocortisone / Q000378:metabolism*; D011863:Radioimmunoassay; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000378:metabolism* / Q000635:transmission; D041201:Taenia solium / Q000302:isolation & purification* / Q000502:physiology; D013622:Taeniasis / Q000453:epidemiology / Q000378:metabolism / Q000662:veterinary*; D013636:Tanzania / Q000453:epidemiology
D003687:Dehydroepiandrosterone; D006854:Hydrocortisone
Dehydroepiandrosterone (DHEA); Hair cortisol; T. solium cysticercosis