Updated association of tea consumption and bone mineral density: A meta-analysis.
BACKGROUND
Current studies evaluating the association of tea consumption and bone mineral density (BMD) have yielded inconsistent findings. Therefore, we conducted a meta-analysis to assess the relationship between tea consumption and BMD.


METHODS
The PubMed, Embase, and Cochrane Library databases were comprehensively searched, and a meta-analysis performed of all observational studies assessing the association of tea consumption and BMD. Forest plots were used to illustrate the results graphically. The Q-test and I statistic were employed to evaluate between-study heterogeneity. Potential publication bias was assessed by the funnel plot.


RESULTS
Four cohort, 1 case-control, and 8 cross-sectional studies including a total of 12,635 cases were included. Tea consumption was shown to prevent bone loss [odds ratio (OR): 0.66; 95% confidence interval (CI), 0.47-0.94; P = 0.02], yielding higher mineral densities in several bones, including the lumbar spine [standardized mean difference (SMD): 0.19; 95% CI, 0.08-0.31; P = 0.001], hip (SMD: 0.19; 95% CI, 0.05-0.34; P = 0.01), femoral neck [mean difference (MD): 0.01; 95% CI, 0.00-0.02; P = 0.04], Ward triangle (MD: 0.02; 95% CI, 0.01-0.04; P = 0.001), and greater trochanter (MD: 0.03; 95% CI, 0.02-0.04; P < 0.00001), than the non-tea consumption group.


CONCLUSIONS
This meta-analysis provided a potential trend that tea consumption might be beneficial for BMD, especially in the lumbar spine, hip, femoral neck, Ward triangle, and greater trochanter, which might help prevent bone loss.
Department of Orthopedic Surgery, Huadu District People's Hospital of Guangzhou, Guangdong, China.
Zhao-Fei
ZF
Zhang
Jun-Long
JL
Yang
Huan-Chang
HC
Jiang
Zheng
Z
Lai
Feng
F
Wu
Zhi-Xiang
ZX
Liu
D015519:Bone Density / Q000187:drug effects*; D005269:Femur / Q000187:drug effects; D005272:Femur Neck / Q000187:drug effects; D006801:Humans; D008159:Lumbar Vertebrae / Q000187:drug effects; D064887:Observational Studies as Topic; D010024:Osteoporosis / Q000517:prevention & control; D010384:Pelvic Bones / Q000187:drug effects; D013662:Tea
D013662:Tea