Photobiomodulation with LED and laser in repair of mandibular socket rabbit: clinical evaluation, histological, and histomorphometric.
OBJECTIVE
The aim of this study was to evaluate the effects of LED and low-intensity laser on the healing of rabbit dental alveoli.


METHODS
A total of 18 rabbits were divided into three groups of six; all rabbits underwent surgical extraction of the first lower right premolar. Following surgery, group 1 received LED irradiation, group 2 received laser irradiation, and group 3 were untreated controls. The initial applications of LED and laser began 48 h after tooth extraction and were given perpendicularly to the dental alveoli. The three groups were clinically evaluated for 18 days in the postoperative period. At 90 days, the rabbits were euthanized and the mandibular fragments containing the healing alveoli were collected. These fragments initially underwent computed tomography scans and bone density was measured in Hounsfield units. Following this, the fragments were processed and stained with hematoxylin and eosin for histological and histomorphometric analysis.


RESULTS
The results were compatible between the clinical, histological, and histomorphometric parameters evaluated. There were no statistical differences between the LED and laser groups. However, the difference of the average bone density between laser and control group was not statistically significant.


CONCLUSIONS
It was found that photobiomodulation with LASER and LED presented effects. However, only the LED demonstrated a beneficial effect on the process of bone repair in the dental alveoli of rabbits.
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, CEP 31270-901, 6627, Pampulha, Belo Horizonte, MG, Brazil.
Cláudio Rômulo
CR
Comunian
Department of Morphology, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, CEP 31270-901, 6627, Pampulha, Belo Horizonte, MG, Brazil.
Antônio Luis Neto
ALN
Custódio
Pontifícia Universidade Católica de Minas Gerais, Av. Dom José Gaspar, 500, CEP 30535-901, Coração Eucarístico, Belo Horizonte, MG, Brazil. leojunq@hotmail.com.
Leandro Junqueira
LJ
de Oliveira
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, CEP 31270-901, 6627, Pampulha, Belo Horizonte, MG, Brazil.
Carlos Eduardo Assis
CEA
Dutra
FAINOR, Rua Geisiel Norberto, CEP 45000, Vitória da Conquista, BA, 1360, Brazil.
Milton
M
D'almeida Ferreira Neto
Department of Clinic and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, CEP 31270-901, 6627, Pampulha, Belo Horizonte, MG, Brazil.
Cleuza Maria Faria
CMF
Rezende
D000818:Animals; D015519:Bone Density / Q000502:physiology; D028022:Low-Level Light Therapy / Q000379:methods*; D011817:Rabbits; D020390:Tooth Socket / Q000473:pathology*; D014945:Wound Healing / Q000502:physiology*
Healing bone; LED; Laser; Photobiomodulation