Carcinosarcoma of the bladder following local schistosomiasis infection.
A young patient from central Africa presented acute renal insufficiency due to extrinsic compression of the distal ureters by a pelvic mass. After initial medical management, a biopsy revealed poorly differentiated bladder cancer andSchistosoma haematobiumeggs embedded in the bladder wall. The initial workup showed evidence of locoregional disease. Radical cystectomy with an incontinent urinary diversion was performed with no complications. Carcinosarcoma of the bladder was diagnosed by pathological analysis of the surgical specimen. After a short follow-up, the patient was readmitted presenting with lung and bone metastases. At 60 days after diagnosis, he died of respiratory insufficiency caused by pulmonary metastatic disease.
Department of Urology, University of Sao Paulo Medical School, Sao Paulo, SP, Brazil.
Victor
V
Srougi
Department of Urology, University of Sao Paulo Medical School, Sao Paulo, SP, Brazil.
Fabio P
FP
Gallucci
Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, SP, Brazil.
Romulo L
RL
Mattedi
Department of Urology, University of Sao Paulo Medical School, Sao Paulo, SP, Brazil.
Miguel
M
Srougi
D000328:Adult; D000818:Animals; D002296:Carcinosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D015653:Cystectomy / Q000379:methods; D017809:Fatal Outcome; D006417:Hematuria / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary; D008297:Male; D009403:Nephrostomy, Percutaneous; D010270:Parasite Egg Count; D051437:Renal Insufficiency / Q000209:etiology; D012548:Schistosoma haematobium / Q000302:isolation & purification; D012552:Schistosomiasis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000469:parasitology; D012553:Schistosomiasis haematobia / Q000000981:diagnostic imaging / Q000469:parasitology; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014547:Urinary Diversion