[Sexual dysfunction associated with psychotropic drugs and treatment options].
BACKGROUND
Sexual dysfunction associated with psychotropic drugs is a threat to patient quality of life and a major reason for non-compliance. Psychotropic agents can impair the sexual response in different ways due to their neurobiological mode of action.


OBJECTIVE
Presentation of the frequencies of sexual functional disorders for selected psychopharmacological groups and the available treatment modalities.


METHODS
Literature search, selection and review of relevant studies.


RESULTS
The most relevant groups for impairments are antidepressants and antipsychotics due to the serotonin agonistic and anti-dopaminergic properties as well as the prolactin increasing characteristics. Agents with a favorable side effects profile are now available. All phases of the sexual response are affected.


CONCLUSIONS
The treatment of psychiatric disorders should follow a comprehensive treatment plan that anticipates a likely sexual dysfunction at the initiation of treatment. The main aim is improvement of the underlying primary disorder. Some limited evidence-based treatment strategies are available.
Klinik für Psychiatrie und Psychotherapeutische Medizin, Städtisches Klinikum Karlsruhe, Kaiserallee 10, 76133, Karlsruhe, Deutschland. Michael.Berner@klinikum-karlsruhe.de.|Medizinische Fakultät, Albert-Ludwigs-Universität, Breisacher Str. 153, 79110, Freiburg, Deutschland. Michael.Berner@klinikum-karlsruhe.de.
M
M
Berner
D000928:Antidepressive Agents / Q000009:adverse effects*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D008297:Male; D011619:Psychotropic Drugs / Q000009:adverse effects*; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy*; D020018:Sexual Dysfunctions, Psychological / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome
D000928:Antidepressive Agents; D011619:Psychotropic Drugs
Antidepressants; Antipsychotics; Sexuality; Side effects; Treatment