Varicella in a Previously Immune Patient With Leukemia.
Infection with varicella-zoster virus (VZV) in oncology patients can result in severe disease with an increased risk of morbidity and mortality [1, 2]. Among patients on cancer chemotherapy, only nonimmune persons are considered to be susceptible to varicella [1]. We present a case of varicella in a child with leukemia that occurred despite immunity as defined by 2 doses of varicella vaccine and documentation of positive VZV immunoglobulin G titer before initiation of chemotherapy.
Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park.|Hofstra Northwell School of Medicine, Hempstead, New York.
Michelle
M
Sewnarine
Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park.|Hofstra Northwell School of Medicine, Hempstead, New York.
Sujatha
S
Rajan
Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park.|Hofstra Northwell School of Medicine, Hempstead, New York.
Arlene
A
Redner
Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park.|Hofstra Northwell School of Medicine, Hempstead, New York.
Lorry G
LG
Rubin
D000212:Acyclovir / Q000627:therapeutic use; D000914:Antibodies, Viral / Q000276:immunology; D000998:Antiviral Agents / Q000627:therapeutic use; D002644:Chickenpox / Q000188:drug therapy / Q000209:etiology*; D019433:Chickenpox Vaccine / Q000627:therapeutic use; D002648:Child; D014645:Herpesvirus 3, Human / Q000276:immunology; D006801:Humans; D008297:Male; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*
D000914:Antibodies, Viral; D000998:Antiviral Agents; D019433:Chickenpox Vaccine; D000212:Acyclovir
immunocompromised; immunoprophylaxis; leukemia; varicella.