IVIG - A cure to severe refractory NAP-1Clostridium difficilecolitis? A case of successful treatment of severe infection, which failed standard therapy including fecal microbiota transplants and fidaxomicin.
The mainstay treatment ofClostridium difficileinfections (CDI) is antimicrobials with growing support for fecal microbiota transplants. We report the first case of an elderly man with severe refractory NAP-1 pseudomembranous CDI who failed all medical therapy and two fecal transplants with response only seen after administration of intravenous immunoglobulin.
Department of Medicine, NYU Langone Medical Center, New York, NY, USA.
Kelley
K
Coffman
Department of Pharmacy, NYU Langone Medical Center, New York, NY, USA.
Xian Jie Cindy
XJ
Chen
Department of Medicine, NYU Lutheran Medical Center, Brooklyn, NY, USA.
Charles
C
Okamura
Department of Medicine, Department of Infectious Diseases & Immunology, NYU Langone Medical Center, New York, NY, USA.
Eddie
E
Louie
C diff; CDI; Clostridium difficile infection; IVIG; Intravenous immunoglobulin