The Impact of Negative Pressure Wound Therapy on Orthopaedic Infection.
By hastening the resolution of edema and improving local microcirculation, topical negative pressure wound therapy (TNP) aids the establishment of early wound coverage. Its use in the setting of type III open fractures is reviewed. The author's initial use of TNP for closed surgical incisions and how it morphed its way into being applied to closed surgical wounds with heightened likelihood for infection is presented. Several case studies are presented to illustrate the role and the technique for management of acute or subacute infections involving bone and implant.
Department of Orthopaedic Trauma, Medical Center Navicent Health, 840 Pine Street, Macon, GA 31201, USA; Department of Surgery, Mercer University School of Medicine, 1400 Coleman Avenue, Macon, GA 31217, USA; Department of Orthopaedic Surgery, Medical Center, Wake Forest University, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Electronic address: Webb.Lawrence@navicenthealth.org.
Lawrence X
LX
Webb
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D019637:Orthopedic Procedures / Q000009:adverse effects*; D053038:Quorum Sensing; D013530:Surgical Wound Infection / Q000382:microbiology / Q000628:therapy; D014022:Tissue Survival; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents
Antibiotic beads; Integra; Negative pressure wound therapy; Quorum sensing; Surgical site infection; Tissue demarcation; Topical negative pressure; Wound coverage