Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft-Versus-Host Disease.
Eosinophilic pustular folliculitis (EPF) is a rare cutaneous disorder that typically occurs in three clinical contexts: men, individuals who are immunosuppressed or have human immunodeficiency virus, and infants. A fourth subtype occurring 2 to 3 months after hematopoietic stem cell transplantation (HSCT) has recently been described in several adults. We report two cases of EPF arising in children after HSCT. It is important to recognize this form of EPF after HSCT and differentiate it from graft-versus-host disease since it responds readily to topical steroids and appears to have an excellent prognosis.
Department of Pediatric Dermatology, University Children's Hospital Zurich, Zurich, Switzerland.|Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Martin
M
Theiler
Ronald O. Perelman Department of Dermatology, School of Medicine, New York University, New York, New York.
Vikash S
VS
Oza
Department of Pediatrics, University of California, San Francisco, California.|Department of Dermatology, University of California, San Francisco, California.
Erin F
EF
Mathes
Department of Pediatrics, University of California, San Francisco, California.
Christopher C
CC
Dvorak
Department of Dermatology, University of California, San Francisco, California.|Department of Pathology, University of California, San Francisco, California.
Timothy H
TH
McCalmont
Department of Dermatology, University of California, San Francisco, California.|Department of Pathology, University of California, San Francisco, California.
Iwei
I
Yeh
Department of Pediatrics, Division of Dermatology, Seattle Children's Hospital and School of Medicine, University of Washington, Seattle, Washington.
Robert
R
Sidbury
Department of Pediatrics, University of California, San Francisco, California.|Department of Dermatology, University of California, San Francisco, California.
Kelly M
KM
Cordoro
D002648:Child; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D005499:Folliculitis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D005938:Glucocorticoids / Q000627:therapeutic use*; D006086:Graft vs Host Disease / Q000175:diagnosis*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D033581:Stem Cell Transplantation / Q000009:adverse effects*
D005938:Glucocorticoids; D007166:Immunosuppressive Agents