Serum Level of Zinc and Copper in Sudanese Women with Polycystic Ovarian Syndrome.
The study aimed to evaluate the serum level of zinc and copper in women with polycystic ovarian syndrome (PCOS). A case-control study was conducted at Saad Abualila infertility center (Khartoum, Sudan). The cases were women who had a PCOS based on Rotterdam criteria. The controls were infertile women with no evidence of PCOS. The socio-demographic characteristics and medical history data were gathered using questionnaires. Zinc and copper levels were measured using atomic absorption spectrophotometer. While there was no difference in zinc and copper levels between the two groups (50 women in each arm), mean (SD) of body mass index (BMI) was significantly higher in women with PCOS compared to the controls [28.4 (4.2) vs. 25.6 (5.7) kg/m2; P = 0.006], respectively. There were no significant differences in the level of luteinizing hormone (LH), follicle stimulating hormone (FSH), LH/FSH, prolactin, testosterone, cholesterol, triglycerides and low-density lipoprotein (LDL) between the cases and the controls. In linear regression analyses, none of the investigated factors were associated with PCOS. Zinc and copper were not associated with PCOS in this setting.
Faculty of Medicine, Al-Neelain University, P.O Box 12702, 11111, Khartoum, Sudan.
Manal E
ME
Sharif
Faculty of Medicine, University of Khartoum, P.O Box 102, 11111, Khartoum, Sudan.
Isahg
I
Adam
Faculty of Medicine, University of Khartoum, P.O Box 102, 11111, Khartoum, Sudan.
Mohamed A
MA
Ahmed
Faculty of Medicine, University of Khartoum, P.O Box 102, 11111, Khartoum, Sudan.
Duria A
DA
Rayis
Faculty of Medicine, Al-Neelain University, P.O Box 12702, 11111, Khartoum, Sudan. hamdanology@hotmail.com.|Al-Neelain Institute for Medical Research (NIMR), Al-Neelain University, Khartoum, Sudan. hamdanology@hotmail.com.
Hamdan Z
HZ
Hamdan
D015992:Body Mass Index; D016022:Case-Control Studies; D003300:Copper / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D013397:Sudan; D013739:Testosterone / Q000097:blood; D015032:Zinc / Q000097:blood*
D013739:Testosterone; D003300:Copper; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D015032:Zinc
Copper; Polycystic ovary syndrome; Sudan; Zinc