Levetiracetam and topiramate poisoning: Two overdoses on those drugs with no lasting effects.
Levetiracetam and topiramate are newer anticonvulsants, which is why international data on overdoses of these drugs are lacking. Only a few mild adverse reactions have been noted. These anticonvulsants have been the drug of choice for neurologists. Despite their wide usage, there is a dearth of literature on symptoms and signs of their toxicity. Presented here is the case of a 21-year-old female who overdosed twice on levetiracetam and topiramate. The woman was admitted and discharged after the first overdose. Ten days later, she took multiple tablets of both drugs and was seen again. Amazingly, the woman went home after the incident with no complications at all.
Emergency Department, Fujairah Hospital.
Moaziz
M
Sarfaraz
Emergency Department, Masafi Hospital.
Rana Hasan
RH
Syeda
D000927:Anticonvulsants / Q000506:poisoning*; D000931:Antidotes / Q000627:therapeutic use*; D002606:Charcoal / Q000627:therapeutic use*; D062787:Drug Overdose / Q000188:drug therapy*; D005260:Female; D005632:Fructose / Q000031:analogs & derivatives* / Q000506:poisoning; D006801:Humans; D000077287:Levetiracetam; D010889:Piracetam / Q000031:analogs & derivatives* / Q000506:poisoning; D000077236:Topiramate; D055815:Young Adult
D000927:Anticonvulsants; D000931:Antidotes; D000077236:Topiramate; D002606:Charcoal; D005632:Fructose; D000077287:Levetiracetam; D010889:Piracetam
Anticonvulsants; activated charcoal; gastrointestinal decontamination; seizures; toxicity