Collecting Duct Renal Cell Carcinoma Found to Involve the Collecting System During Partial Nephrectomy: A Case Report.
Collecting duct carcinoma (CDC) is a rare and aggressive form of renal cell carcinoma (RCC) arising from the principal cells of the collecting duct. One third of cases present with metastatic disease, but many present in a manner similar to conventional RCC or urothelial carcinoma (UC). We discuss a case of CDC which presented as a small mass at the cortico-medullary junction, and was discovered at robotic partial nephrectomy (RPN) to be grossly involving the collecting system. A 62-year-old man presented with a small renal mass suspicious for RCC, which was found on computed tomography (CT) after an episode of gross hematuria. After thorough workup, RPN was attempted; however, intraoperatively the mass was found to be involving the collecting system. Radical nephroureterectomy was performed, and the pathology report revealed CDC. CDC is a rare and aggressive form of RCC. While many cases are metastatic at diagnosis, most patients present with the incidental finding of a small renal mass. There are no reports of a CDC involving the collecting system at RPN after negative ureteroscopy preoperatively. The adjuvant therapeutic options for CDC are limited, and long term survival is poor.
Department of Urology; Department of Pathology, Temple University Hospital, 3401 N, Broad Street, Philadelphia, PA 19147, USA.
Andrew C
AC
Harbin
Department of Urology; Department of Pathology, Temple University Hospital, 3401 N, Broad Street, Philadelphia, PA 19147, USA.
Brett A
BA
Styskel
Department of Urology; Department of Pathology, Temple University Hospital, 3401 N, Broad Street, Philadelphia, PA 19147, USA.
Viren
V
Patel
Department of Urology; Department of Pathology, Temple University Hospital, 3401 N, Broad Street, Philadelphia, PA 19147, USA.
He
H
Wang
Department of Urology; Department of Pathology, Temple University Hospital, 3401 N, Broad Street, Philadelphia, PA 19147, USA.
Daniel D
DD
Eun