Total body irradiation with a compensator fabricated using a 3D optical scanner and a 3D printer.
We propose bilateral total body irradiation (TBI) utilizing a 3D printer and a 3D optical scanner. We acquired surface information of an anthropomorphic phantom with the 3D scanner and fabricated the 3D compensator with the 3D printer, which could continuously compensate for the lateral missing tissue of an entire body from the beam's eye view. To test the system's performance, we measured doses with optically stimulated luminescent dosimeters (OSLDs) as well as EBT3 films with the anthropomorphic phantom during TBI without a compensator, conventional bilateral TBI, and TBI with the 3D compensator (3D TBI). The 3D TBI showed the most uniform dose delivery to the phantom. From the OSLD measurements of the 3D TBI, the deviations between the measured doses and the prescription dose ranged from  -6.7% to 2.4% inside the phantom and from  -2.3% to 0.6% on the phantom's surface. From the EBT3 film measurements, the prescription dose could be delivered to the entire body of the phantom within  ±10% accuracy, except for the chest region, where tissue heterogeneity is extreme. The 3D TBI doses were much more uniform than those of the other irradiation techniques, especially in the anterior-to-posterior direction. The 3D TBI was advantageous, owing to its uniform dose delivery as well as its efficient treatment procedure.
Department of Radiation Oncology, Seoul National University Hospital, Seoul 03080, Republic of Korea. Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul 03080, Republic of Korea. Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Republic of Korea. Center for Convergence Research on Robotics, Advanced Institutes of Convergence Technology, Suwon 16229, Republic of Korea.
So-Yeon
SY
Park
Jung-In
JI
Kim
Yoon Ha
YH
Joo
Jung Chan
JC
Lee
Jong Min
JM
Park
D006801:Humans; D019047:Phantoms, Imaging; D066330:Printing, Three-Dimensional / Q000295:instrumentation*; D011829:Radiation Dosage; D000072232:Radiation Dosimeters / Q000592:standards*; D011879:Radiotherapy Dosage; D014916:Whole-Body Irradiation / Q000295:instrumentation / Q000379:methods*