Lidocaine gel versus plain lubricating gel for pain reduction during transrectal sonography (LIPS): A randomized controlled trial.
OBJECTIVE
To compare the efficacy and safety of lidocaine gel and plain lubricating gel in relieving pain during transrectal sonography (TRS) in patients with gynecologic problems.


METHODS
A randomized controlled trial was conducted in 80 participants who were scheduled to undergo TRS. The participants were allocated into the lidocaine gel group and the aqueous gel group at a 1:1 ratio. The intensity of pain during TRS based on the visual analogue scale (0-10 points) and the adverse events were assessed and compared between the two groups.


RESULTS
The two groups had similar demographic characteristics. Between the lidocaine and aqueous gel groups, there was no significant difference in the pain score at probe manipulation (4.04±2.14 vs. 4.21±2.79; P=0.868), as well as at baseline, probe insertion, and 5min after probe removal. The degree of acceptability of the sonographer also did not differ between the two groups. No acute and delayed adverse events was occurred.


CONCLUSIONS
Intrarectal lidocaine gel for TRS provides no analgesic benefit compared with aqueous gel.
Department of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Su Hyun
SH
Nam
Department of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Kye Hyun
KH
Kim
Department of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Chahien
C
Choi
Department of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Se Hyun
SH
Nam
Department of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address: taejong.song@gmail.com.
Taejong
T
Song
Department of Obstetrics & Gynecology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Kyo Won
KW
Lee
D000285:Administration, Rectal; D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage*; D019160:Endosonography / Q000009:adverse effects* / Q000379:methods; D005260:Female; D005782:Gels / Q000008:administration & dosage; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D054327:Lubricants / Q000008:administration & dosage*; D010147:Pain Measurement; D000073818:Procedural Pain / Q000175:diagnosis / Q000517:prevention & control*; D055815:Young Adult
D000779:Anesthetics, Local; D005782:Gels; D054327:Lubricants; D008012:Lidocaine
Lidocaine gel; Local anesthesia; Pain; Transrectal sonography