[Vasopressors and inotropes: use in paediatrics].
The cardiovascular system is a dynamic system, which is required to ensure adequate delivery of oxygen, nutrients, and hormones to the tissues that are necessary for cell metabolism. It also synthesises and modifies the vasoactive components that regulate vascular tone and myocardial function. These vasoactive components have demonstrated their beneficial effects in the management of paediatric patients in a critical condition with heart failure and shock. However, their use and abuse brings harmful effects, increases mortality, and is associated with arrhythmias. An increase in myocardial oxygen consumption favours the presence of ischaemia, therefore it is necessary to know the mechanism of action and indications of these drugs to minimise their harmful effects. The purpose of this review is to describe the pharmacology and clinical applications of inotropic and vasopressor agents in the paediatric patient in acritical condition.
Departamento de Terapia Intensiva Pediátrica, Hospital Regional Valentín Gómez Farías, ISSSTE, Zapopan, Jalisco, México. Electronic address: agc_13@outlook.com.
Adrián
A
García-Canales
Departamento de Cardiología Pediátrica, Hospital General de Occidente, Zapopan, Jalisco, México.
Rocío Alejandra
RA
Peña-Juárez
Departamento de Cardiología Pediátrica, Hospital Climosal, Santa Tecla, La Libertad, El Salvador.
Luz de María
LM
Sandoval-Franco
D002316:Cardiotonic Agents / Q000627:therapeutic use*; D002648:Child; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*
D002316:Cardiotonic Agents; D014662:Vasoconstrictor Agents
Choque; Falla cardiaca; Heart failure; Inotropes; Inotrópicos; Mexico; México; Shock; Vasopresores; Vasopressors