Capecitabine-induced lichenoid drug eruption: a case report.
Capecitabine is a 5-fluorouracil basedchemotherapeutic drug widely used in the treatmentof solid tumors, especially colorectal and breast. Someof the most common side effects of capecitabine arecutaneous in nature, including hand-foot syndrome(palmar-plantar erythrodysesthesia). Several reports inthe literature link capecitabine use with photosensitivelichenoid eruptions. Herein, we present a case ofcapecitabine-induced lichenoid eruption in an elderlyfemale with metastatic breast cancer and discuss ourfindings in relationship to previously reported cases ofthis and other capecitabine-induced skin pathologies.
Jeff R
JR
Gehlhausen
Matthew B
MB
Strausburg
Mouhammad
M
Aouthmany
Terrence M
TM
Katona
Richard L. Roudebush VA Medical Center, Indianapolis, Indiana. turner41@iu.edu.
Matthew J
MJ
Turner
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy*; D000069287:Capecitabine / Q000009:adverse effects*; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D005542:Forearm; D006801:Humans; D017512:Lichenoid Eruptions / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D008875:Middle Aged
D000964:Antimetabolites, Antineoplastic; D000069287:Capecitabine