Readout-segmented echo-planar diffusion-weighted imaging in the assessment of orbital tumors: comparison with conventional single-shot echo-planar imaging in image quality and diagnostic performance.
Background Readout-segmented echo-planar imaging (RS-EPI) could improve the imaging quality of diffusion-weighted imaging (DWI) in various organs. However, whether it could improve the imaging quality and diagnostic performance for the patients with orbital tumors is still unknown. Purpose To compare the image quality and diagnostic performance of RS-EPI DWI with that of conventional single-shot EPI (SS-EPI) DWI in patients with orbital tumors. Material and Methods SS-EPI and RS-EPI DW images of 32 patients with pathologically diagnosed orbital tumors were retrospectively analyzed. Qualitative imaging parameters (imaging sharpness, geometric distortion, ghosting artifacts, and overall imaging quality) and quantitative imaging parameters (apparent diffusion coefficient [ADC], signal-to-noise ratio [SNR], contrast, and contrast-to-noise ratio [CNR]) were assessed by two independent radiologists, and compared between SS-EPI and RS-EPI DWI. Receiver operating characteristic curves were used to determine the diagnostic value of ADC in differentiating malignant from benign orbital tumors. Results RS-EPI DW imaging produced less geometric distortion and ghosting artifacts, and better imaging sharpness and overall imaging quality than SS-EPI DWI (for all, P < 0.001). Meanwhile, RS-EPI DWI produced significantly lower SNR ( P < 0.001) and ADC ( P < 0.001), and higher contrast ( P < 0.001) than SS-EPI DWI, while producing no difference in CNR ( P = 0.137). There was no significant difference on the diagnostic performance between SS-EPI and RS-EPI DWI, when using ADC as the differentiating index ( P = 0.529). Conclusion Compared with SS-EPI, RS-EPI DWI provided significantly better imaging quality and comparable diagnostic performance in differentiating malignant from benign orbital tumors.
1 Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Xiaoquan
X
Xu
1 Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Yanjun
Y
Wang
1 Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Hao
H
Hu
1 Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Guoyi
G
Su
2 Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Hu
H
Liu
1 Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Haibin
H
Shi
1 Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China.
Feiyun
F
Wu
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D017352:Echo-Planar Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000000981:diagnostic imaging; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012189:Retrospective Studies
Orbit; diffusion-weighted imaging; magnetic resonance imaging (MRI); readout-segmented echo-planar imaging; single-shot echo-planar imaging