Efficacy of Sonoelastography in Distinguishing Benign from Malignant Breast Masses.
OBJECTIVE
The study aimed to evaluate the influence of sonoelastographic strain ratio in distinguishing benign from malignant breast masses.


METHODS
Patients who were referred for diagnostic biopsy of a breast mass were examined by ultrasound and sonoelastography prior to percutaneous biopsy. Sonoelastography was performed twice by the same observer in the same session. The strain ratios (SR) were calculated for both measurements as well as the mean strain ratio. Results were compared with histopathologic findings. For each strain ratio, a threshold value was determined using a ROC analysis for the differentiation of benign and malignant masses.


RESULTS
After histopathological examination of 135 mass lesions in 132 female patients (mean age 48±12 years), 65 masses were diagnosed as benign and 70 as malignant. According to the Tsukuba classification with 5 scores; 44 of 65 benign masses had scores of either 1 or 2 while 56 of 70 malignant lesions had scores of either 4 or 5. No benign lesion was classified as score 5, and no malignant lesion as score 1. The mean cut-off in the two ROC measurements in distinguishing benign from malignant lesions was calculated as 4.52. When a threshold value of 4.52 was used for the mean strain ratio: the sensitivity, specificity, PPV, NPV, and accuracy rates were determined as 85.5%, 84.8%, 85.5%, 84.8% and 85.2%, respectively.


CONCLUSIONS
The threshold value for strain ratio in the differentiation of benign and malignant masses was detected as 4.52, and a significant intra-observer difference was not observed in this study. The diagnostic value of sonoelastograghy in distinguishing benign from malignant breast masses was higher in comparison to conventional ultrasound.
Clinic of Radiology, Afyonkarahisar State Hospital, Afyonkarahisar, Turkey.
Adile
A
Balçık
Department of Radiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.
Ahmet Veysel
AV
Polat
Department of Radiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.
İlkay Koray
İK
Bayrak
Department of General Surgery, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey.
Ayfer Kamalı
AK
Polat
Breast neoplasm; sonoelastography; ultrasound