Osteoporosis in Frail Patients: A Consensus Paper of the Belgian Bone Club.
In this consensus paper, the Belgian Bone Club aims to provide a state of the art on the epidemiology, diagnosis, and management of osteoporosis in frail individuals, including patients with anorexia nervosa, patients on dialysis, cancer patients, persons with sarcopenia, and the oldest old. All these conditions may indeed induce bone loss that is superimposed on physiological bone loss and often remains under-recognized and under-treated. This is of particular concern because of the major burden of osteoporotic fractures in terms of morbidity, mortality, and economic cost. Therefore, there is an urgent need to appreciate bone loss associated with these conditions, as this may improve diagnosis and management of bone loss and fracture risk in clinical practice.
Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, KU Leuven & Center for Metabolic Bone Diseases, UZ Leuven, Herestraat 49, 3000, Leuven, Belgium. evelien.gielen@uzleuven.be.
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Gielen
Department of Radioisotopes, CHU Brugmann, Université Libre de Bruxelles, Bruxelles, Belgium.
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Bergmann
Department of Public Health, Epidemiology and Health Economics, University of Liège, CHU de Liège, Liège, Belgium.
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Bruyère
Department of Clinical Chemistry, UnilabLg, CIRM, University of Liège, CHU de Liège, Liège, Belgium.
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Cavalier
Department of Nephrology, Dialysis, Transplantation, University of Liège, CHU de Liège, Liège, Belgium.
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Delanaye
Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium.
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Goemaere
Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium.|Department of Endocrinology, Ghent University Hospital, Ghent, Belgium.
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Kaufman
Department of Public Health, Epidemiology and Health Economics, University of Liège, CHU de Liège, Liège, Belgium.
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M
Locquet
Department of Public Health, Epidemiology and Health Economics, University of Liège, CHU de Liège, Liège, Belgium.
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Reginster
Department of Gynaecology-Obstetrics, Université Libre de Bruxelles, Bruxelles, Belgium.
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Rozenberg
Clinical Department of Internal Medicine, UZ Leuven, Leuven, Belgium.
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Vandenbroucke
Department of Medicine, CHU Brugmann, Université Libre de Bruxelles, Bruxelles, Belgium.
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Body
D000368:Aged; D000818:Animals; D001530:Belgium; D001851:Bone Diseases, Metabolic / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D050723:Fractures, Bone / Q000175:diagnosis / Q000628:therapy; D016330:Frail Elderly; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D055948:Sarcopenia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
Anorexia nervosa; Cancer; Dialysis; Elderly; Frailty; Osteoporosis; Sarcopenia