Plant transcription factors from the homeodomain-leucine zipper family I. Role in development and stress responses.
In front of stressful conditions plants display adaptation mechanisms leading to changes in their morphology, physiology, development and molecular composition. Transcription factors (TFs) play crucial roles in these complex adaptation processes. This work is focused in the homeodomain-leucine zipper I (HD-Zip I) family of TFs, unique to plants. First discovered in 1991, they were identified and isolated from monocotyledonous and dicotyledonous plants showing high structural similarity and diversified functions. These TFs have, besides the homeodomain and leucine zipper, conserved motifs in their carboxy-termini allowing the interaction with the basal machinery and with other regulatory proteins. The model dicotyledonous plant Arabidopsis thaliana has 17 HD-Zip I members; most of them regulated by external stimuli and hormones. These TFs are involved in key developmental processes like root and stem elongation, rosette leaves morphology determination, inflorescence stem branching, flowering and pollen hydration. Moreover, they are key players in responses to environmental stresses and illumination conditions. Several HD-Zip I encoding genes from different species were protected in patents because their overexpression or mutation generates improved agronomical phenotypes. Here we discuss many aspects about these TFs including structural features, biological functions and their utilization as biotechnological tools to improve crops. © 2017 IUBMB Life, 69(5):280-289, 2017.
Instituto de Agrobiotecnología del Litoral Universidad Nacional del Litoral, CONICET, Centro Científico Tecnológico CONICET Santa Fe, Santa Fe, Argentina.
María Florencia
MF
Perotti
Instituto de Agrobiotecnología del Litoral Universidad Nacional del Litoral, CONICET, Centro Científico Tecnológico CONICET Santa Fe, Santa Fe, Argentina.
Pamela Anahí
PA
Ribone
Instituto de Agrobiotecnología del Litoral Universidad Nacional del Litoral, CONICET, Centro Científico Tecnológico CONICET Santa Fe, Santa Fe, Argentina.
Raquel Lía
0000-0002-3264-0008
RL
Chan
D017360:Arabidopsis / Q000378:metabolism; D001709:Biotechnology / Q000379:methods; D018506:Gene Expression Regulation, Plant; D018398:Homeodomain Proteins / Q000378:metabolism; D016350:Leucine Zippers; D005810:Multigene Family; D009154:Mutation; D063245:Plant Development; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics; D013312:Stress, Physiological; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D018398:Homeodomain Proteins; D010940:Plant Proteins; D014157:Transcription Factors
Arabidopsis thaliana; HD-Zip I; biotechnological tools; homeodomain-leucine zipper; transcription factors