Lost in translation? microRNAs at the rough ER.
MicroRNAs (miRNAs) function to post-transcriptionally regulate target RNAs, including long non-coding RNAs and mRNAs. A recent study demonstrates that Arabidopsis miRNAs are enriched at the rough endoplasmic reticulum (ER). This enrichment is a surprise, given that most known miRNA targets are not expected to be translated at the rough ER.
Department of Biology and Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802 USA. Electronic address: mja18@psu.edu.
Michael J
MJ
Axtell
D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000235:genetics / Q000378:metabolism; D035683:MicroRNAs / Q000235:genetics; D014176:Protein Biosynthesis / Q000235:genetics / Q000502:physiology; D012333:RNA, Messenger / Q000235:genetics
D035683:MicroRNAs; D012333:RNA, Messenger