Circular stapling versus triangulating stapling for the cervical esophagogastric anastomosis after esophagectomy in patients with thoracic esophageal cancer: A prospective, randomized, controlled trial.
Several studies have reported that the triangulating stapling method decreases the incidence of anastomotic stricture after esophagectomy, but no randomized, controlled trial has confirmed the efficacy of the triangulating stapling method for cervical esophagogastrostomy. We compared triangulating stapling and circular stapling for cervical esophagogastric anastomosis regarding the decrease in anastomotic stricture after esophagectomy for thoracic esophageal cancer.



Between August 2010 and April 2014, 100 patients enrolled in this randomized, controlled trial at the Wakayama Medical University Hospital were allocated randomly to either the circular stapling group (n = 49) or the triangulating stapling group (n = 51). The primary end point was the incidence of anastomotic stricture within 12 months postoperatively. This randomized, controlled trial was registered with the University Hospital Medical Information Network Clinical Trial Registry (UMIN000004848).



There were no differences between the circular stapling and triangulating stapling groups in terms of clinical data. The amount of time required for esophagogastric anastomosis was slightly greater for the triangulating stapling group (22 minutes) than for the circular stapling group (18 minutes) (P = .028). Anastomotic stricture occurred in 8 patients (17%) in the circular stapling group and 9 patients (19%) in the triangulating stapling group (P = .935). The rate of anastomotic leakage was 11% for the circular stapling group and 2% for the triangulating stapling group (P = .073).



The triangulating stapling method for cervical anastomosis for thoracic esophageal cancer does not decrease the incidence of anastomotic stricture compared with the circular stapling method within 12 postoperative months but may affect the rate of anastomotic leakage.
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Keiji
K
Hayata
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Mikihito
M
Nakamori
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Masaki
M
Nakamura
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Toshiyasu
T
Ojima
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Makoto
M
Iwahashi
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Masahiro
M
Katsuda
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Toshiaki
T
Tsuji
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Tomoya
T
Kato
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Jyunya
J
Kitadani
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Akihiro
A
Takeuchi
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Hirotaka
H
Tabata
Second Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan. Electronic address: yamaue-h@wakayama-med.ac.jp.
Hiroki
H
Yamaue
D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D000714:Anastomosis, Surgical / Q000379:methods; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery*; D016629:Esophagectomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control*; D011446:Prospective Studies; D017792:Surgical Stapling / Q000379:methods*; D016896:Treatment Outcome