Neuroendocrine Tumors of the Stomach.
Gastric neuroendocrine tumors (NETs) are classified into three types. Type I gastric NETs are associated with chronic atrophic gastritis. They have a good prognosis and endoscopic resection is the mainstay of treatment. Type II gastric NETs are caused by hypergastrinemia. They have a poorer prognosis, and resection is required to control the disease. Endoscopic versus surgical resection is recommended for the gastric lesion. Type III gastric NETs are sporadic and not associated with any specific condition. They have the worst prognosis with the highest rate of metastatic disease, and oncologic resection is recommended. Medical therapies have some role.
Department of Surgery, University of Alabama at Birmingham, KB 404, 1720 2nd Avenue South, Birmingham, AL 35294, USA. Electronic address: blprince@uabmc.edu.
Britney
B
Corey
Department of Surgery, UAB Hospital and Health System, UAB Comprehensive Cancer Center, University of Alabama at Birmingham, BDB 502, 1808 7th Avenue South, Birmingham, AL 35233, USA.
Herbert
H
Chen
D055088:Early Detection of Cancer / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D018358:Neuroendocrine Tumors / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016896:Treatment Outcome
Chronic atrophic gastritis; Gastric carcinoid; Gastric neuroendocrine tumor; Sporadic carcinoid; Zollinger-Ellison syndrome