Systemic insecticides used in dogs: potential candidates for phlebotomine vector control?
Zoonotic visceral leishmaniasis (ZVL) is a public health problem endemic in some countries. Current control measures, in particular culling infected dogs, have not reduced ZVL incidence in humans. We evaluated the use of five systemic insecticides (spinosad, fluralaner, afoxolaner, sarolaner and moxidectin) currently used in dogs for other purposes (e.g. tick, flea control) in controlling ZVL transmission. The anti-phlebotomine capacity of these compounds confirmed in experimental studies makes their use in ZVL control programmes very promising. Limitations and benefits of using this new control tool are compared to current practices.
Barcelona Institute for Global Health, Barcelona, Spain.
Sonia Ares
SA
Gomez
Barcelona Institute for Global Health, Barcelona, Spain.
Albert
A
Picado
D000818:Animals; D004199:Disease Vectors; D004283:Dog Diseases / Q000469:parasitology / Q000517:prevention & control* / Q000635:transmission; D004285:Dogs; D019353:Endemic Diseases; D006801:Humans; D007313:Insecta; D007306:Insecticides / Q000494:pharmacology*; D018314:Leishmania infantum; D007898:Leishmaniasis, Visceral / Q000469:parasitology / Q000517:prevention & control* / Q000635:transmission / Q000662:veterinary; D011576:Psychodidae / Q000187:drug effects* / Q000469:parasitology; D011634:Public Health; D015047:Zoonoses
D007306:Insecticides
Leishmaniosis Visceral Zoonótica (LVZ); chiens; dogs; insecticidas sistémicos; insecticides systémiques; leishmaniose viscérale zoonotique; perros; phlebotomine vectors; systemic insecticides; vecteurs phlébotomes; vectores flebotomíneo; zoonotic visceral leishmaniais