Complications in Donors Using Right Liver Graft: Analysis of 280 Consecutive Cases.
BACKGROUND
Living donor liver transplantation (LDLT) is performed with increasing frequency worldwide due to the shortage of donated organs. It is a life-saving procedure for the recipient, but, on the other hand, a major surgical procedure for healthy donors and it may cause morbidity and even mortality.


METHODS
This research was completed at Dokuz Eylül University Faculty of Medicine Hospital General Surgery Department Liver Transplant Unit and included 280 cases (4 with simultaneous liver and kidney transplants from living donors) who underwent donor right hepatectomy for LDLT from June 2000 to June 2016. We analyzed the data of patients retrospectively.


RESULTS
Of 280 donor right hepatectomies for LDLT, 181 were male (M; 64.6%) and 99 were female (F; 35.4%) (M/F: 1.82). Mean donor age was 31.2 ± 0.9 years (range, 18-56). Mean donor monitoring duration was 45 ± 2.4 months (range, 3-192 months). Mean body mass index (BMI) was 24.28 ± 2.96 kg/m2(range, 18.1-32.42 kg/m2). In our study 72 cases (25.7%) developed postoperative complications. There were 17 Clavien grade 3A, 1 grade 3B, and 5 grade 4A complications and also 1 death due to pulmonary embolism.


CONCLUSIONS
Together with the increase in living donor surgery, the morbidity and mortality of these cases are becoming controversial. Full donor safety is only possible with appropriate donor choice requiring very detailed studies, a problem-free hepatectomy process, and close postoperative donor monitoring.
Department of General Surgery, Dokuz Eylul University School of Medicine, İzmir, Turkey. Electronic address: mucahitozbilgin@gmail.com.
M
M
Özbilgin
Department of General Surgery, Dokuz Eylul University School of Medicine, İzmir, Turkey.
T
T
Ünek
Department of General Surgery, Dokuz Eylul University School of Medicine, İzmir, Turkey.
T
T
Egeli
Department of General Surgery, Dokuz Eylul University School of Medicine, İzmir, Turkey.
C
C
Ağalar
Department of Anaesthesiology and Intensive Care, Dokuz Eylul University School of Medicine, İzmir, Turkey.
S
S
Ozkardesler
Department of General Surgery, Dokuz Eylul University School of Medicine, İzmir, Turkey.
E
E
Karadeniz
Department of Medical Informatics and Biostatistics, Dokuz Eylul University School of Medicine, İzmir, Turkey.
H
H
Ellidokuz
Department of Radiology, Dokuz Eylul University School of Medicine, İzmir, Turkey.
F
F
Obuz
Department of General Surgery, Dokuz Eylul University School of Medicine, İzmir, Turkey.
I
I
Astarcıoğlu
D000293:Adolescent; D000328:Adult; D046148:Donor Selection; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D061214:Patient Safety; D011183:Postoperative Complications / Q000209:etiology; D012189:Retrospective Studies; D060053:Transplant Donor Site; D019737:Transplants; D055815:Young Adult