First report on isolation of 2,3,4-trihydroxy-5-methylacetophenone from palmyra palm (Borassus flabellifer Linn.) syrup, its antioxidant and antimicrobial properties.
The first report on isolation and characterization of 2,3,4-trihydroxy-5-methylacetophenone (1), nicotinamide (2), and uracil (3) from palmyra palm syrup is described. Total phenolic content (TPC) and Total flavonoid content (TFC) of palm syrup were 244.70±5.77(mggallic acid/kg of syrup) and 658.45±27.86(mg quercetin/kg of syrup), respectively. Compound 1 exhibited DPPH radical scavenging activity with an IC50value of 20.02±0.14μM which was better than ascorbic acid (IC50=22.59±0.30μM). Compound 1 also showed broad spectrum antibacterial activity against Escherichia coli, Mycobacterium smegmatis, Staphylococcus aureus and Staphylococcus simulans.
Agro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram 695019, Kerala, India. Electronic address: reshmamv2001@gmail.com.
M V
MV
Reshma
Agro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram 695019, Kerala, India.
Jubi
J
Jacob
Agro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram 695019, Kerala, India.
V L
VL
Syamnath
Agro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram 695019, Kerala, India.
V P
VP
Habeeba
Agro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram 695019, Kerala, India.
B S
BS
Dileep Kumar
Chemical Sciences and Technology Division and Academy of Scientific and Innovative Research (AcSIR), CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram 695019, Kerala, India. Electronic address: ravishankar@niist.res.in.
Ravi S
RS
Lankalapalli
D000098:Acetophenones / Q000737:chemistry / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000975:Antioxidants; D028023:Arecaceae / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*
D000098:Acetophenones; D000900:Anti-Bacterial Agents; D000975:Antioxidants; D010936:Plant Extracts
2,3,4-Trihydroxy-5-methylacetophenone; Antibacterial activity; Antioxidant activity; Palmyra palm syrup; Polyphenol