Incidental Malignancies Identified During Staging for Prostate Cancer With68Ga Prostate-specific Membrane Antigen HBED-CC Positron Emission Tomography Imaging.
The rapid uptake of68Ga prostate-specific membrane antigen HBED-CC positron emission tomography (PSMA PET) imaging for prostate cancer staging has led to concerns regarding its specificity, with uptake in both malignant and nonmalignant tissues. We describe 3 separate malignancies identified on PSMA PET imaging. The misnomer "prostate-specific membrane antigen" is demonstrated by this case and highlights the importance of continued investigation of the potential role of PSMA PET in other malignancies.
Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia; Australian Prostate Cancer Research Centre-Queensland, Transitional Research Institute, Brisbane, Queensland, Australia. Electronic address: drejoshi@gmail.com.
Andre
A
Joshi
Australian Prostate Cancer Research Centre-Queensland, Transitional Research Institute, Brisbane, Queensland, Australia; Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Cheryl
C
Nicholson
Australian Prostate Cancer Research Centre-Queensland, Transitional Research Institute, Brisbane, Queensland, Australia; Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Handoo
H
Rhee
Department of Radiology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Sonja
S
Gustafson
Department of Radiology, Princess Alexandra Hospital, Brisbane, Queensland, Australia; Institute of Nuclear Medicine, University College London, London, United Kingdom.
Kenneth
K
Miles
Australian Prostate Cancer Research Centre-Queensland, Transitional Research Institute, Brisbane, Queensland, Australia; Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Ian
I
Vela