Ag/AgO Nanoparticles Grown via Time Dependent Double Mechanism in a 2D Layered Ni-PCP and Their Antibacterial Efficacy.
A simple synthesis route for growth of Ag/AgO nanoparticles (NPs) in large quantitative yields with narrow size distribution from a functional, non-activated, Ni (II) based highly flexible porous coordination polymer (PCP) as a template has been demonstrated. This template is a stable storage media for the NPs larger than the pore diameters of the PCP. From EPR study it was concluded that NPs were synthesized via two mechanisms i.e. acid formation and the redox activity of the framework. Size range of Ag/AgO NPs is sensitive to choice of solvent and reaction time. Direct use of Ag/AgO@Ni-PCP shows influential growth inhibition towards Escherichia coli and the pathogen Salmonella typhimurium at extremely low concentrations. The pristine template shows no cytotoxic activity, even though it contains Ni nodes in the framework.
Department of Chemistry, Indian Institute of Technology Kanpur, 208016, India.
Rashmi A
RA
Agarwal
Department of Mechanical Engineering, Indian Institute of Technology Kanpur, 208016, India.
Neeraj K
NK
Gupta
Department of Biological Science and Bioengineering, Indian Institute of Technology Kanpur, 208016, India.
Rajan
R
Singh
Department of Biological Science and Bioengineering, Indian Institute of Technology Kanpur, 208016, India.
Shivansh
S
Nigam
Department of Biological Science and Bioengineering, Indian Institute of Technology Kanpur, 208016, India.
Bushra
B
Ateeq
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D053768:Metal Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D000073396:Metal-Organic Frameworks / Q000737:chemistry / Q000494:pharmacology / Q000648:ultrastructure; D008826:Microbial Sensitivity Tests; D018625:Microscopy, Atomic Force; D008958:Models, Molecular; D008968:Molecular Conformation; D009532:Nickel / Q000737:chemistry; D010087:Oxides / Q000737:chemistry / Q000494:pharmacology; D010316:Particle Size; D012834:Silver / Q000737:chemistry / Q000494:pharmacology; D018030:Silver Compounds / Q000737:chemistry / Q000494:pharmacology; D014961:X-Ray Diffraction
D000900:Anti-Bacterial Agents; D000073396:Metal-Organic Frameworks; D010087:Oxides; D018030:Silver Compounds; D012834:Silver; D009532:Nickel; C040225:disilver oxide