Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015.
We conducted a retrospective observational study at four German university hospitals of patients with laboratory-confirmed influenza in 2014/2015. Overall, a fatality rate of 8% was observed. Significantly more A(H1N1)pdm09 patients were admitted to ICU compared to those with A(H3N2). However, fatal outcome was not significantly increased among A(H1N1)pdm09 cases. Nosocomial infections were seen in 17% of cases. Systematic collection of data from hospitals will complement national influenza surveillance.
Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany.
Robert
R
Heyd
Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.
Anna Maria
AM
Eis-Hübinger
Institute for Medical Virology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Annemarie
A
Berger
Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany.
Sibylle
S
Bierbaum
Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.
Sandra
S
Pietzonka
Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany.
Jürgen J
JJ
Wenzel
Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany.
Daniela
D
Huzly
Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.|Max von Pettenkofer-Institut, Virology, Ludwig Maximilian University of Munich, Munich, Germany.
Oliver T
OT
Keppler
Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany. marcus.panning@uniklinik-freiburg.de.
Marcus
M
Panning
D000328:Adult; D000368:Aged; D003428:Cross Infection / Q000453:epidemiology* / Q000821:virology*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006785:Hospitals, University; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification / Q000502:physiology*; D053122:Influenza A Virus, H3N2 Subtype / Q000302:isolation & purification / Q000502:physiology*; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies
Epidemiology; Influenza; Nosocomial; Observational study; University hospital