Red Emission B, N, S-co-Doped Carbon Dots for Colorimetric and Fluorescent Dual Mode Detection of Fe3+Ions in Complex Biological Fluids and Living Cells.
Colorimetric and fluorescent dual mode detection methods have gained much attention in recent years; however, it is still desirable to develop new colorimetric and fluorescent dual mode nanosensors with more simple preparation procedures, low cost, and excellent biocompatibility. Herein, a colorimetric and fluorescent nanosensor based on B, N, S-co-doped carbon dots (BNS-CDs) was synthesized by one-step hydrothermal treatment of 2,5-diaminobenzenesulfonic acid and 4-aminophenylboronic acid hydrochloride. Using this nanosensor, a highly sensitive assay of Fe3+in the range of 0.3-546 μM with a detection limit of 90 nM was provided by quenching the red emission fluorescence. It is more attractive that Fe3+can also be visualized by this nanosensor via evident color changes of the solution (from red to blue) under sunlight without the aid of an ultraviolet (UV) lamp. Furthermore, the designed nanosensor can be applied for efficient detection of intracellular Fe3+with excellent biocompatibility and cellular imaging capability, and it holds great promise in biomedical applications.
College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou 730000, China.
Yinghua
Y
Liu
School of Life Sciences, University of Science and Technology of China , Hefei 230027, China.
Wenxiu
W
Duan
College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou 730000, China.
Wei
W
Song
College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou 730000, China.
Juanjuan
J
Liu
College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou 730000, China.
Cuiling
http://orcid.org/0000-0002-0037-1149
C
Ren
College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou 730000, China.
Jiang
J
Wu
School of Life Sciences, University of Science and Technology of China , Hefei 230027, China.
Dan
D
Liu
College of Chemistry and Chemical Engineering, Lanzhou University , Lanzhou 730000, China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou 730000, China.
Hongli
H
Chen
D002244:Carbon; D002412:Cations; D003124:Colorimetry; D007501:Iron; D057230:Limit of Detection; D045663:Quantum Dots
D002412:Cations; D002244:Carbon; D007501:Iron
Fe3+ detection; cell imaging; colorimetric and fluorescent; dual mode; red emission carbon dots