Therapeutics for Equine Gastric Ulcer Syndrome.
Equine gastric ulcer syndrome (EGUS) is an umbrella term used to describe ulcers in the nonglandular squamous and glandular mucosa, terminal esophagus, and proximal duodenum. Gastric ulcers in the squamous and glandular regions occur more often than esophageal or duodenal ulcers and likely have a different pathogenesis. At present, omeprazole is accepted globally as the best pharmacologic therapy for both regions of the stomach; however, the addition of coating agents and synthetic prostaglandins could add to its effectiveness in treatment of EGUS. Dietary and environmental management are necessary for prevention of recurrence.
University of Tabriz, 29th Bahman Boulevard, Tabriz 5166616471, Iran.
Fereydon Rezazadeh
FR
Zavoshti
Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Skip Bertman Drive, LA 70803, USA. Electronic address: fandrews@lsu.edu.
Frank M
FM
Andrews
D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D006734:Horse Diseases / Q000188:drug therapy / Q000473:pathology / Q000517:prevention & control / Q000628:therapy*; D006736:Horses; D009853:Omeprazole / Q000627:therapeutic use; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D013276:Stomach Ulcer / Q000473:pathology / Q000517:prevention & control / Q000628:therapy / Q000662:veterinary*
D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors; D009853:Omeprazole
Equine; Equine gastric ulcer syndrome; Gastric ulcer; Horse; Therapeutics