Aryl Fluorosulfate Trapped Staudinger Reduction.
A chemoselective Staudinger reduction/sulfur(VI) fluoride exchange cascade has been developed to join two chemical segments through an aryl sulfamate ester (RNH-SO2-OAr) linkage. Aryl fluorosulfate is exploited in this work as the first tetrahedral electrophilic trap for the in situ generated iminophosphorane. Ten examples using azide-containing compounds are presented.
Department of Applied Chemistry, School of Food Science and Biotechnology, Zhejiang Gongshang University , Hangzhou 310035, China.
Gerui
G
Ren
Qinheng
0000-0002-8440-8673
Q
Zheng
Hua
0000-0003-3760-090X
H
Wang
D001386:Azides; D017611:Fluorine Compounds / Q000737:chemistry*; D015394:Molecular Structure; D013457:Sulfur Compounds / Q000737:chemistry*
D001386:Azides; D017611:Fluorine Compounds; D013457:Sulfur Compounds