Medical mistrust as a key mediator in the association between perceived discrimination and adherence to antiretroviral therapy among HIV-positive Latino men.
Discrimination has been found to have deleterious effects on physical health. The goal of the present study was to examine the association between perceived discrimination and adherence to antiretroviral therapy (ART) among HIV-positive Latino men and the extent to which medical mistrust serves as a mediator of that association. A series of linear and logistic regression models was used to test for mediation for three types of perceived discrimination (related to being Latino, being perceived as gay and being HIV-positive). Medical mistrust was found to be significantly associated with perceived discrimination based on Latino ethnicity and HIV serostatus. Medical mistrust was found to mediate the associations between two types of perceived discrimination (related to being Latino and being HIV-positive) and ART adherence. Given these findings, interventions should be developed that increase the skills of HIV-positive Latino men to address both perceived discrimination and medical mistrust.
Bienestar Human Services, Inc., 5326 East Beverly Blvd., Los Angeles, CA, 90022, USA. fgalvan@bienestar.org.
Frank H
FH
Galvan
RAND Corporation, 1776 Main Street, Santa Monica, CA, 90407, USA.
Laura M
LM
Bogart
RAND Corporation, 1776 Main Street, Santa Monica, CA, 90407, USA.
David J
DJ
Klein
RAND Corporation, 1776 Main Street, Santa Monica, CA, 90407, USA.
Glenn J
GJ
Wagner
Bienestar Human Services, Inc., 5326 East Beverly Blvd., Los Angeles, CA, 90022, USA.
Ying-Tung
YT
Chen
D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D015658:HIV Infections / Q000188:drug therapy / Q000523:psychology*; D006630:Hispanic or Latino / Q000523:psychology*; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D063508:Social Discrimination / Q000208:ethnology*; D035502:Trust / Q000523:psychology*
D044966:Anti-Retroviral Agents
Antiretroviral therapy; Discrimination; HIV/AIDS; Latino/Hispanic; Medication adherence; Men who have sex with men