Optimized Acquisition Time for Dopamine Transporter Imaging.
Excess acquisition counts were often obtained by the current image acquisition of 30 minutes after123I-ioflupane administration in a dopamine transporter study. The purpose of this study was to calculate the minimum acquisition time while retaining sufficient image quality, which could be adjusted for individual characteristics. Fifty patients who underwent dopamine transporter imaging were included in this retrospective study. The brain count density, determined by a striatum phantom, was compared to the participant's characteristics. The individual characteristics were divided into five categories of gender, age, height, weight, and body mass index. The values of 40 counts / voxel (brain count density) were set as the image quality criteria by the striatum phantom study. Weight was the characteristic that most correlated with brain count density in the 50 patients (correlation coefficient: -0.728). The acquisition time for the 50 patients was calculated as 23.4±2.6 minutes using the following formula: 0.332×W+5.42 minutes (W kg (individual weight)). A shorter acquisition time with sufficient image quality can be achieved by adjusting for individual patient weight.
Department of Radiology, Kochi Medical School Hospital.
Naoya
N
Hayashi
Naoki
N
Akagi
Masataka
M
Sawada
Akiko
A
Hirota
Kenji
K
Ito
D000368:Aged; D001921:Brain; D001923:Brain Chemistry; D050483:Dopamine Plasma Membrane Transport Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D019047:Phantoms, Imaging; D013679:Technology, Radiologic; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon
D050483:Dopamine Plasma Membrane Transport Proteins