Generalized bullous fixed drug eruption treated with cyclosporine.
Fixed drug eruptions (FDE) comprise 10 percent of alladverse cutaneous drug reactions and generalizedbullous fixed drug eruptions (GBFDE) are a raresubset of FDEs. We present a patient with severeGBFDE caused by ibuprofen successfully treated withcyclosporine. Further work is needed to determine ifcyclosporine can be an effective therapy for GBFDE.
Neeta
N
Malviya
Nika
N
Cyrus
Travis
T
Vandergriff
Department of Dermatology, University of Texas Southwestern Medical Center. Melissa.Mauskar@UTSouthwestern.edu.
Melissa
M
Mauskar
D061605:Administration, Intravenous; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001768:Blister / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D016572:Cyclosporine / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D003875:Drug Eruptions / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008297:Male
D000894:Anti-Inflammatory Agents, Non-Steroidal; D003879:Dermatologic Agents; D016572:Cyclosporine; D007052:Ibuprofen