INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters.
Chair for Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany. kemter@genzentrum.lmu.de.|Centre for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany. kemter@genzentrum.lmu.de.
Elisabeth
E
Kemter
Paul Langerhans Institute Dresden (PLID) of Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus of Technische Universität Dresden, Helmholtz Zentrum München, Neuherberg, Germany.|DFG-Centre for Regenerative Therapies Dresden (CRTD), Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.|German Center for Diabetes Research (DZD), Munich, Neuherberg, Germany.
Christian M
CM
Cohrs
Diabetes Division, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
Matthias
M
Schäfer
Diabetes Center-Medical Clinic Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität, LMU Munich, Munich, Germany.
Marion
M
Schuster
Diabetes Division, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
Klaus
K
Steinmeyer
Diabetes Center-Medical Clinic Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität, LMU Munich, Munich, Germany.
Lelia
L
Wolf-van Buerck
Diabetes Division, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
Andrea
A
Wolf
Chair for Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.|Centre for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.
Annegret
A
Wuensch
Chair for Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.|Centre for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.
Mayuko
M
Kurome
Chair for Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.|Centre for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.
Barbara
B
Kessler
Chair for Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.|Centre for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.
Valeri
V
Zakhartchenko
Diabetes Division, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
Matthias
M
Loehn
Diabetes Division, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
Yuri
Y
Ivashchenko
Diabetes Center-Medical Clinic Campus Innenstadt, Medizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität, LMU Munich, Munich, Germany.
Jochen
J
Seissler
Diabetes Division, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
Anke M
AM
Schulte
Paul Langerhans Institute Dresden (PLID) of Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus of Technische Universität Dresden, Helmholtz Zentrum München, Neuherberg, Germany.|DFG-Centre for Regenerative Therapies Dresden (CRTD), Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.|German Center for Diabetes Research (DZD), Munich, Neuherberg, Germany.
Stephan
S
Speier
Chair for Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.|Centre for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.|German Center for Diabetes Research (DZD), Munich, Neuherberg, Germany.
Eckhard
E
Wolf
D000818:Animals; D030801:Animals, Genetically Modified; D000831:Animals, Newborn; D005786:Gene Expression Regulation / Q000235:genetics; D005947:Glucose / Q000494:pharmacology; D049452:Green Fluorescent Proteins / Q000235:genetics*; D006801:Humans; D007328:Insulin / Q000235:genetics* / Q000378:metabolism; D050417:Insulin-Secreting Cells / Q000378:metabolism; D007515:Islets of Langerhans / Q000502:physiology*; D016381:Islets of Langerhans Transplantation; D008297:Male; D051379:Mice; D016688:Mice, Inbred NOD; D010179:Pancreas / Q000166:cytology* / Q000196:embryology / Q000254:growth & development*; D034421:Sus scrofa; D013552:Swine
D007328:Insulin; D049452:Green Fluorescent Proteins; D005947:Glucose
Islet maturation; Pig; Reporter gene; Xenotransplantation