New Task Force Criteria Provide Evolution in Diagnosis of Arrhythmogenic Cardiomyopathy in Patients without Typical Progression of the Disease.
BACKGROUND The original Task Force Criteria from 1994 for the clinical diagnosis of ARVC were highly specific and based on structural, histological, EKG, and familial features of disease. However, recommendations for clinical diagnosis and management of ARVC are sparse and lacked sensitivity for early disease. CASE REPORT Ventricular electrical instability and sudden cardiac death are the hallmarks of ARVC, and are often present before structural abnormalities. In this case report, we describe a patient who had detectable electrical abnormalities and structural changes that remained unchanged for over 10 years. CONCLUSIONS The disease progression in this case was defined as the development of a new 2010 TFC, which was absent at enrolment in 1994 and in 2008.
Department of Internal Medicine, Division of Cardiology and Angiology, University Hospital of Giessen and Marburg, Marburg, Germany.
Mariana S
MS
Parahuleva
Department of Diagnostic and Interventional Radiology, University Hospital of Giessen and Marburg, Marburg, Germany.
Jens
J
Figiel
Department of Internal Medicine, Division of Cardiology and Angiology, University Hospital of Giessen and Marburg, Marburg, Germany.
Holger
H
Ahrens
Department of Internal Medicine, Division of Cardiology and Angiology, University Hospital of Giessen and Marburg, Marburg, Germany.
Bernhard
B
Schieffer
Department of Internal Medicine, Division of Cardiology and Angiology, University Hospital of Giessen and Marburg, Marburg, Germany.
Dimitar
D
Divchev
Department of Internal Medicine, Division of Cardiology and Angiology, University Hospital of Giessen and Marburg, Marburg, Germany.
Ulrich
U
Lüsebrink
D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000175:diagnosis*; D002037:Bundle-Branch Block / Q000209:etiology; D018450:Disease Progression; D004562:Electrocardiography; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D017180:Tachycardia, Ventricular / Q000209:etiology