Associated Risk of Malignancy in Patients with Cardiovascular Disease: Evidence and Possible Mechanism.
Cardiovascular disease and malignancy are leading causes of morbidity and mortality. Increased risk of malignancy was identified in patients with cardiovascular disease, including patients with heart failure, heart failure after myocardial infarction, patients undergoing cardiac intervention, and patients after a thrombotic event. Common risk factors and biological pathways can explain this association and are explored in this review. Further research is needed to establish the causes of malignancy in this population and direct possible intervention.
Department of Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel. Electronic address: hasint@szmc.org.il.
Tal
T
Hasin
Department of Cardiology, Rabin Medical Center, Petach Tiqwa, Israel.
Zaza
Z
Iakobishvili
Department of Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel.
Giora
G
Weisz
D001778:Blood Coagulation Disorders / Q000150:complications; D002318:Cardiovascular Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D057890:Epigenomics; D006801:Humans; D000860:Hypoxia / Q000150:complications; D007249:Inflammation / Q000150:complications; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology; D009369:Neoplasms / Q000209:etiology*; D000069079:Radiation Exposure / Q000009:adverse effects; D012038:Regeneration; D012307:Risk Factors
Cardiovascular; Causality; Heart failure; Malignancy; Risk factors