The BDNFval66metpolymorphism and individual differences in temperament in 4-month-old infants: A pilot study.
Individual differences in infants' temperament are under genetic control. We investigated the association between brain-derived-neurotrophic-factor (BDNFval66met) polymorphism and temperament in 63 full-term infants. Met-carriers (N=25) had lower Regulatory capacities compared to val-homozygotes (N=38). These findings suggest that the BDNF polymorphism affects early temperament individual differences.
0-3 Center for the at-Risk Infant, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, LC, Italy.
Lorenzo
L
Giusti
0-3 Center for the at-Risk Infant, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, LC, Italy. Electronic address: livio.provenzi@bp.lnf.it.
Livio
L
Provenzi
Laboratory of Cellular Biochemistry and Molecular Biology, CriBeNS, Catholic University, Milan, Italy.
Daniela
D
Tavian
Laboratory of Cellular Biochemistry and Molecular Biology, CriBeNS, Catholic University, Milan, Italy.
Sara
S
Missaglia
0-3 Center for the at-Risk Infant, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, LC, Italy.
Niccolò
N
Butti
0-3 Center for the at-Risk Infant, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, LC, Italy.
Rosario
R
Montirosso
D019208:Brain-Derived Neurotrophic Factor / Q000235:genetics*; D005260:Female; D005838:Genotype; D006801:Humans; D007206:Individuality; D007223:Infant; D008297:Male; D010865:Pilot Projects; D011110:Polymorphism, Genetic; D013694:Temperament
D019208:Brain-Derived Neurotrophic Factor; C579455:BDNF protein, human
BDNF; Genetics; Infant; Polymorphism; Temperament