Dermatomyositis, clinically presenting with cutaneous ulcers, with histopathologic evidence of perforating collagenosis.
Dermatomyositis is a systemic, autoimmune diseasewith a variety of clinical features that often includemyositis and characteristic cutaneous findings. Asubset of patients with dermatomyositis developcutaneous ulcers, often in the setting of vasculitis orvasculopathy. We present a case of dermatomyositiswith cutaneous ulcers that show perforatingcollagenosis on histopathologic examination.Acquired reactive perforating collagenosistypically occurs in the setting of diabetes mellitus,chronic renal failure, and other pruritic conditions,and this case represents a rare association withdermatomyositis, which may ultimately be helpful inelucidating the pathophysiology of this perforatingdisorder.
Ronald O. Perelman Department of Dermatology, NYU School of Medicine, NYU Langone Medical Center.
Rachel
R
Rosenstein
Kathryn
K
Martires
Mitalee
M
Christman
Vitaly
V
Terushkin
Shane A
SA
Meehan
Nicole
N
Seminara
Brian D
BD
Golden
Andrew G
AG
Franks
D003095:Collagen Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003882:Dermatomyositis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005121:Extremities; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D005260:Female; D006229:Hand Dermatoses / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D012536:Scalp Dermatoses / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D012883:Skin Ulcer / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D060726:Torso