Preliminary Study on Quantitative Sleep EEG Characteristics in Patients with Schizophrenia.
We used quantitative electroencephalography (EEG) spectral analysis to compare activity in the bilateral frontal, central, and occipital areas in nine patients with schizophrenia and ten healthy control subjects during standard nocturnal polysomnography. Patients with schizophrenia had longer sleep latency than controls. In N2 sleep, the patients had significantly lower 0.5-1 Hz power and higher theta power in the left frontal region, and higher beta power in the left occipital region than did control subjects. In N3 sleep, the patients with schizophrenia had significantly higher alpha power in the left occipital region than did controls. These findings show distinctive EEG sleep patterns in patients with schizophrenia, which may reflect brain dysfunction or medication effects.
Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul, Republic of Korea.
Seong Min
SM
Oh
Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul, Republic of Korea.
Yu Jin
YJ
Lee
Cooperative Research Centre for Alertness, Safety and Productivity, The University of Sydney, Sydney, Australia.; Sleep and Circadian Group, Woolcock Institute of Medical Research, Glebe, Australia.; School of Physics, The University of Sydney, Sydney, Australia.
Jong Won
JW
Kim
Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul, Republic of Korea.
Jae Won
JW
Choi
Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul, Republic of Korea.
Do-Un
DU
Jeong
Electroencephalography; Schizophrenia; Sleep