Converging on RAS.
Biologists at the Frederick National Laboratory for Cancer Research have teamed up with computer scientists and physicists at the Department of Energy to tackle the problem of "undruggable" RAS. The goal is to obtain a precise understanding of how RAS is activated by interactions with the plasma membrane; this will be illuminated through supercomputer simulations that build on structural and biochemical studies of RAS.
D000818:Animals; D003201:Computers; D006801:Humans; D000075762:Interdisciplinary Research / Q000639:trends; D012984:Software; D018631:ras Proteins / Q000502:physiology*
D018631:ras Proteins