KOREAN PEDIATRIC AND ADULT HEAD COMPUTATIONAL PHANTOMS AND APPLICATION TO PHOTON SPECIFIC ABSORBED FRACTIONS CALCULATIONS.
In recent decades, applications of single photon emission computed tomography and positron emission tomography in clinical neuroimaging have markedly increased. In this study, we developed a series of Korean computational head phantoms with detailed cranial substructures for 6-, 9-, 12- and 15-year-old children and adult by non-uniformly adjusting a template head phantom to match the Korean standard head dimensions. The Korean head phantoms were coupled with a Monte Carlo transport code to calculate age-dependent specific absorbed fraction (SAF) for the combination of 10 source and target regions and mono-energetic photons ranging from 0.01 to 4 MeV. Compared to the adult phantom, the 6-y phantom showed up to 1.4-fold greater self-absorption SAF (cerebellum) and up to 1.8-fold greater cross-irradiation SAF (cerebellum < eye balls). With addition of electron SAFs in the future, our photon SAF data will facilitate dose calculations for various cranial substructures in patients undergoing cranial neuroimaging procedures.
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Daphnée
D
Villoing
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Dayton
D
McMillan
Department of Nuclear Engineering, Kyung-Hee University, Yongin, South Korea.
Kwang Pyo
KP
Kim
Department of Nuclear Engineering, Kyung-Hee University, Yongin, South Korea.
Il Park
Radio & Satellite Research Division, Electronics and Telecommunications Research Institute, Daejeon, South Korea.
Ae-Kyoung
AK
Lee
Radio & Satellite Research Division, Electronics and Telecommunications Research Institute, Daejeon, South Korea.
Hyung-do
HD
Choi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Choonsik
C
Lee
D000293:Adolescent; D000328:Adult; D001822:Body Burden; D002648:Child; D003198:Computer Simulation; D006801:Humans; D008953:Models, Anatomic; D009010:Monte Carlo Method; D017785:Photons; D049268:Positron-Emission Tomography; D011829:Radiation Dosage; D056910:Republic of Korea