Degradation of Marine Algae-Derived Carbohydrates by Bacteroidetes Isolated from Human Gut Microbiota.
Carrageenan, agarose, and alginate are algae-derived undigested polysaccharides that have been used as food additives for hundreds of years. Fermentation of dietary carbohydrates of our food in the lower gut of humans is a critical process for the function and integrity of both the bacterial community and host cells. However, little is known about the fermentation of these three kinds of seaweed carbohydrates by human gut microbiota. Here, the degradation characteristics of carrageenan, agarose, alginate, and their oligosaccharides, byBacteroides xylanisolvens,Bacteroides ovatus, andBacteroides uniforms, isolated from human gut microbiota, are studied.
Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and pharmacy, Ocean University of China, Qingdao 266003, China. liaa99@163.com.|Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China. liaa99@163.com.
Miaomiao
M
Li
Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and pharmacy, Ocean University of China, Qingdao 266003, China. shangqingsen@163.com.
Qingsen
Q
Shang
DiSha Pharmaceutical Group, Weihai 264205, China. gsli-87@163.com.
Guangsheng
G
Li
State Key Laboratory of Breeding Base for Zhejiang Sustainable Pest and Disease Control and Zhejiang Key Laboratory of Food Microbiology, Academy of Agricultural Sciences, Hangzhou 310021, China. xxww101@sina.com.
Xin
X
Wang
Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and pharmacy, Ocean University of China, Qingdao 266003, China. glyu@ouc.edu.cn.|Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China. glyu@ouc.edu.cn.
Guangli
G
Yu
D000464:Alginates / Q000378:metabolism; D059001:Aquatic Organisms / Q000378:metabolism*; D041963:Bacteroidetes / Q000378:metabolism*; D002351:Carrageenan / Q000378:metabolism; D005285:Fermentation / Q000502:physiology; D000069196:Gastrointestinal Microbiome / Q000502:physiology*; D020723:Glucuronic Acid / Q000378:metabolism; D006603:Hexuronic Acids / Q000378:metabolism; D006801:Humans; D064307:Microbiota / Q000502:physiology; D009844:Oligosaccharides / Q000378:metabolism*; D011134:Polysaccharides / Q000378:metabolism*; D012624:Seaweed / Q000378:metabolism*; D012685:Sepharose / Q000378:metabolism
D000464:Alginates; D006603:Hexuronic Acids; D009844:Oligosaccharides; D011134:Polysaccharides; D020723:Glucuronic Acid; D002351:Carrageenan; D012685:Sepharose
Bacteroides ovatus; Bacteroides uniforms; Bacteroides xylanisolvens; agarose; alginate; carrageenan; oligosaccharides