Public attitudes in Japan towards human-animal chimeric embryo research using human induced pluripotent stem cells.
To understand the steps and objectives for which Japanese people are willing to accept human-animal chimeric embryo research using human induced pluripotent stem cells.



An internet-based survey was conducted for the general public and researchers in Japan in 2016.



Over 60% of the public and 83.8% of researchers supported the creation of human-swine chimeras and 81.0% of the public and 92.4% of researchers supported the creation of human-swine chimeric embryos.



When presented with a graded view of human-swine chimeric embryo research with concomitant, specific objectives, a large majority of the general public as well as researchers are willing to accept this research with the aims of disease study, novel drug and treatment development, and transplantation.
Uehiro Research Division for iPS Cell Ethics, Center for iPS Cell Research & Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Tsutomu
T
Sawai
Uehiro Research Division for iPS Cell Ethics, Center for iPS Cell Research & Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Taichi
T
Hatta
Uehiro Research Division for iPS Cell Ethics, Center for iPS Cell Research & Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Misao
M
Fujita
D000818:Animals; D033041:Embryo Research / Q000941:ethics*; D006801:Humans; D020407:Internet; D007564:Japan; D011639:Public Opinion; D011795:Surveys and Questionnaires; D013552:Swine
Japan; human-induced pluripotent stem cells; human–animal chimeras; human–animal chimeric embryos; public attitudes; questionnaire survey