More Flavor for Flavonoid-Based Interventions?
Poor diets are associated with obesity and a decline in cognitive function. Flavonoids are plant compounds that have been associated with improved metabolic parameters in obesity and reversal of cognitive decline. Given that microbial flavonoid conversion is important for bioactivity, flavonoid-derived neuroactive compounds may be functionally crucial in the gut microbiome-brain axis.
School of Medical Sciences, University of New South Wales (UNSW) Sydney, Kensington, NSW 2052, Australia. Electronic address: n.kaakoush@unsw.edu.au.
Nadeem O
NO
Kaakoush
School of Medical Sciences, University of New South Wales (UNSW) Sydney, Kensington, NSW 2052, Australia. Electronic address: m.morris@unsw.edu.au.
Margaret J
MJ
Morris
D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D001921:Brain / Q000378:metabolism; D003071:Cognition; D003072:Cognition Disorders / Q000209:etiology / Q000378:metabolism / Q000382:microbiology / Q000628:therapy*; D004032:Diet / Q000009:adverse effects; D005419:Flavonoids / Q000378:metabolism* / Q000494:pharmacology / Q000627:therapeutic use*; D055951:Functional Food / Q000032:analysis; D005658:Fungi / Q000378:metabolism; D000069196:Gastrointestinal Microbiome; D006801:Humans; D009765:Obesity / Q000209:etiology / Q000378:metabolism / Q000382:microbiology / Q000628:therapy*; D010944:Plants / Q000378:metabolism; D056692:Prebiotics / Q000032:analysis; D064210:Secondary Metabolism
D000975:Antioxidants; D005419:Flavonoids; D056692:Prebiotics
cognition; flavonoids; gut microbiome; obesity; obesogenic diet