In vitro and in silico evidence against a significant effect of theSPINK1c.194G>A variant on pre-mRNA splicing.
Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai, China.|Institut National de la Santé et de la Recherche Médicale (INSERM), U1078, Brest, France.|Etablissement Français du Sang (EFS)-Bretagne, Brest, France.|Shanghai Institute of Pancreatic Diseases, Shanghai, China.
Hao
H
Wu
Institut National de la Santé et de la Recherche Médicale (INSERM), U1078, Brest, France.|Etablissement Français du Sang (EFS)-Bretagne, Brest, France.
Arnaud
A
Boulling
Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff, UK.
David N
DN
Cooper
Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai, China.|Shanghai Institute of Pancreatic Diseases, Shanghai, China.
Zhao-Shen
ZS
Li
Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai, China.|Shanghai Institute of Pancreatic Diseases, Shanghai, China.
Zhuan
Z
Liao
Institut National de la Santé et de la Recherche Médicale (INSERM), U1078, Brest, France.|Etablissement Français du Sang (EFS)-Bretagne, Brest, France.|Faculté de Médecine et des Sciences de la Santé, Université de Bretagne Occidentale (UBO), Brest, France.
Jian-Min
0000-0002-2424-3969
JM
Chen
Institut National de la Santé et de la Recherche Médicale (INSERM), U1078, Brest, France.|Etablissement Français du Sang (EFS)-Bretagne, Brest, France.|Faculté de Médecine et des Sciences de la Santé, Université de Bretagne Occidentale (UBO), Brest, France.|Laboratoire de Génétique Moléculaire et d'Histocompatibilité, Centre Hospitalier Universitaire (CHU) Brest, Hôpital Morvan, Brest, France.
Claude
C
Férec
D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D009154:Mutation; D010195:Pancreatitis; D050500:Pancreatitis, Chronic; D012322:RNA Precursors; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000235:genetics*
D012322:RNA Precursors; D014359:Trypsin Inhibitor, Kazal Pancreatic
CHRONIC PANCREATITIS; GENE MUTATION; GENETICS; GENOTYPE