Vision-related Quality of Life in Patients with Non-infectious Uveitis: A Cross-sectional Study.
OBJECTIVE
To analyze the influence of socio-demographic, comorbidity, and clinical-related variables in the vision-related quality of life (VR-QoL) of non-infectious uveitis patients.


METHODS
Cross-sectional study includes 156 consecutive non-infectious uveitis patients from a tertiary uveitis clinic from Madrid (Spain). The main outcome was the log-transformed composite score of the Visual Functioning Questionnaire 25. Bivariate and multivariate ordinary least-squares regression models were performed and results expressed using effect sizes with 95% confidence intervals (95% CI).


RESULTS
In the multivariate analysis, one unit increase in the logarithm of the minimum angle of resolution scale [i.e., worse best corrected visual acuity (BCVA)] was associated with a seven times worse VR-QoL (a 0.14-fold change [95% CI: 0.07-0.27]). Patients with ocular comorbidities had a 64% worse VR-QoL (a 0.61-fold change [95% CI: 0.49-0.77]).


CONCLUSIONS
Lower BCVA and the presence of ocular comorbidities had a significant, independent, and deleterious effect in the VR-QoL of non-infectious uveitis patients.
a Ophthalmology Department , Hospital Clínico San Carlos , Madrid , Spain.
Pedro
P
Arriola-Villalobos
b Rheumatology Department , Hospital Clínico San Carlos , Madrid , Spain.|c Health Research Institute (IdISSC) , Hospital Clínico San Carlos , Madrid , Spain.
Lydia
L
Abásolo
a Ophthalmology Department , Hospital Clínico San Carlos , Madrid , Spain.|d Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality , Instituto de Salud Carlos III , Madrid , Spain.
Julián
J
García-Feijoo
b Rheumatology Department , Hospital Clínico San Carlos , Madrid , Spain.
Benjamín
B
Fernández-Gutiérrez
a Ophthalmology Department , Hospital Clínico San Carlos , Madrid , Spain.
Rosalía
R
Méndez-Fernández
b Rheumatology Department , Hospital Clínico San Carlos , Madrid , Spain.
Esperanza
E
Pato
a Ophthalmology Department , Hospital Clínico San Carlos , Madrid , Spain.
David
D
Díaz-Valle
b Rheumatology Department , Hospital Clínico San Carlos , Madrid , Spain.|c Health Research Institute (IdISSC) , Hospital Clínico San Carlos , Madrid , Spain.
Luis
L
Rodriguez-Rodriguez
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires; D014605:Uveitis / Q000453:epidemiology / Q000503:physiopathology / Q000523:psychology*; D014792:Visual Acuity; D055815:Young Adult
Cross-sectional study; ocular comorbidities; uveitis; vision-related quality of life; visual acuity