Primary adrenal diffuse large B-cell lymphoma positive for CD5 and CD10.
A 69-year-old man presented with back pain over the prior few months and was hospitalized because of bilateral adrenal masses and fracture of the left sixth rib. The mass on the right measured 6.5×3.6×7.0 cm, that on the left 8.1×4.8×6.9 cm, on CT. The final diagnosis was CD5- and CD10-positive primary adrenal diffuse large B-cell lymphoma (PA-DLBCL) with rib involvement. After EPOCH therapy accompanied with rituximab and intrathecal treatment, the tumors decreased dramatically. However, he died due to disease progression 8 months after the diagnosis. The prognosis of CD5- and CD10-positive PA-DLBCL may be very poor even with rituximab-containing chemotherapy.
Department of Hematology and Oncology, Okayama City Hospital.
Yoshikazu
Y
Yamamoto
Yuichi
Y
Sumii
Yutaro
Y
Shiraishi
Kazuhiro
K
Ikeuchi
Haruto
H
Yamada
Daigo
D
Niiya
Yasuhiro
Y
Shiote
Kazuhiko
K
Yamamoto
Kenji
K
Imajo
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018956:CD5 Antigens / Q000276:immunology*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D015260:Neprilysin / Q000276:immunology*; D000069283:Rituximab / Q000627:therapeutic use*; D016896:Treatment Outcome
D018956:CD5 Antigens; D000069283:Rituximab; D015260:Neprilysin