Nicotine Content and Physical Properties of Large Cigars and Cigarillos in the United States.
Cigars are combusted tobacco products consisting of filler, binder, and wrapper, which are derived from tobacco. Despite the abundance of literature on the composition of traditional combusted cigarettes, research is limited on the physical and chemical properties of cigars. Therefore, research on cigar properties may be useful to better understand their health impact.



In this study, twenty large cigar and cigarillo products were characterized for physical properties (ie, weight, length, and diameter), filler nicotine content, and tobacco pH. Tobacco pH was used to calculate free nicotine content, free nicotine concentration, and percent free nicotine for all cigars using the Henderson-Hasselbach equation. An additional analysis was performed on a second batch of two large cigar and two cigarillo brands to determine within-brand consistency. All analyses were performed in triplicate.



The initial analysis of the twenty cigars showed that cigars exhibited wide variation in product size and nicotine content, although tobacco pH was similar across cigars. Furthermore, in the two large cigar and cigarillo brands analyzed a second time, there was considerable within-brand variance in nicotine content and concentration between the first and second analyses.



While only a small sample of commercially-available cigars was analyzed, our data suggest there is wide variability in nicotine content and some physical properties in the domestic cigar market. The data may help to inform potential future regulatory decisions related to these products.



This study reveals some of the challenges to experimental cigar research and illustrates the need to characterize cigar products (eg, nicotine and tobacco content) before use in clinical studies. Additional studies and characterization of the physical and chemical properties of cigars may be useful to further understand these products' toxicity, abuse potential, and public health impact.
Battelle Public Health Center for Tobacco Research, Baltimore, MD.
Bartosz
B
Koszowski
Battelle Public Health Center for Tobacco Research, Baltimore, MD.
Meridith Hill
MH
Thanner
Battelle Public Health Center for Tobacco Research, Baltimore, MD.
Wallace B
WB
Pickworth
Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Kenneth M
KM
Taylor
Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Lynn C
LC
Hull
Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Megan J
MJ
Schroeder
D006801:Humans; D009538:Nicotine / Q000032:analysis*; D011634:Public Health / Q000639:trends; D011786:Quality Control; D012907:Smoking / Q000453:epidemiology / Q000639:trends; D062789:Tobacco Products / Q000032:analysis*; D014481:United States / Q000453:epidemiology
D009538:Nicotine