Affibody molecules as engineered protein drugs.
Affibody molecules can be used as tools for molecular recognition in diagnostic and therapeutic applications. There are several preclinical studies reported on diagnostic and therapeutic use of this molecular class of alternative scaffolds, and early clinical evidence is now beginning to accumulate that suggests the Affibody molecules to be efficacious and safe in man. The small size and ease of engineering make Affibody molecules suitable for use in multispecific constructs where AffiMabs is one such that offers the option to potentiate antibodies for use in complex disease.
Affibody AB, Solna, Sweden.|Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Fredrik Y
FY
Frejd
AbClon Inc., Guro-gu, Seoul, Republic of Korea.
Kyu-Tae
KT
Kim
D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000378:metabolism*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D011485:Protein Binding; D015202:Protein Engineering / Q000379:methods*; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism* / Q000627:therapeutic use
D000911:Antibodies, Monoclonal; D011993:Recombinant Fusion Proteins