Optimization of the Compton camera for measuring prompt gamma rays in boron neutron capture therapy.
Optimization of the Compton camera for measuring prompt gamma rays (0.478MeV) emitted during boron neutron capture therapy (BNCT) was performed with Geant4. The parameters of the Compton camera were determined as follows: 3cm thick - 10cm wide scatter detector (Silicon), 10cm thick - 10cm wide absorber detector (Germanium), and 1cm distance between the scatter and absorber detectors. For a typical brain tumor treatment, the overall detection efficiency of the optimized Compton camera was approximately 0.1425% using the Snyder's head phantom with a sphere tumor (4cm diameter and ~1cm depth).
Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China; National Institute of Nuclear Physics, INFN, Section of Pavia, Italy.
Chun-Hui
CH
Gong
Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China; Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Nanjing, China. Electronic address: tangxiaobin@nuaa.edu.cn.
Xiao-Bin
XB
Tang
Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Di-Yun
DY
Shu
Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Hai-Yan
HY
Yu
Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
Chang-Ran
CR
Geng
D016754:Boron Neutron Capture Therapy / Q000706:statistics & numerical data; D001932:Brain Neoplasms / Q000532:radiotherapy; D003198:Computer Simulation; D004867:Equipment Design; D015902:Gamma Cameras / Q000706:statistics & numerical data; D005720:Gamma Rays; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D012542:Scattering, Radiation
Boron neutron capture therapy; Compton camera; Geant4; Prompt gamma rays