Sarcoidosis with prominent necrosis on histopathology.
Sarcoidosis is a multiorgan inflammatory diseasewith variable clinical presentations and the commonhistopathologic finding of noncaseating granulomas.The etiology of the disease is not known, butevidence suggests both environmental and geneticcontributions to the pathogenesis. Depending onthe severity of cutaneous disease and extent ofextracutaneous involvement, therapies range fromtopical and intralesional glucocorticoids to systemicimmunomodulatory and immunosuppressiveagents. We present the case of a patient withcutaneous sarcoidosis with prominent necrosis onhistopathologic examination in the setting of severepulmonary sarcoidosis.
Ronald O. Perelman Department of Dermatology, NYU School of Medicine, NYU Langone Medical Center.
Rachel
R
Rosenstein
Charisse
C
Orme
Randie H
RH
Kim
Shane A
SA
Meehan
Alisa
A
Femia
D000328:Adult; D006801:Humans; D008297:Male; D009336:Necrosis; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D017565:Sarcoidosis, Pulmonary / Q000150:complications; D012867:Skin / Q000473:pathology*