Segmental Vitiligo.
Segmental vitiligo is characterized by its early onset, rapid stabilization, and unilateral distribution. Recent evidence suggests that segmental and nonsegmental vitiligo could represent variants of the same disease spectrum. Observational studies with respect to its distribution pattern point to a possible role of cutaneous mosaicism, whereas the original stated dermatomal distribution seems to be a misnomer. Although the exact pathogenic mechanism behind the melanocyte destruction is still unknown, increasing evidence has been published on the autoimmune/inflammatory theory of segmental vitiligo.
Department of Dermatology, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium. Electronic address: Nanja.vangeel@ugent.be.
Nanja
N
van Geel
Department of Dermatology, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium.
Reinhart
R
Speeckaert
D006801:Humans; D012867:Skin / Q000473:pathology*; D014820:Vitiligo / Q000145:classification / Q000175:diagnosis* / Q000473:pathology
Classification; Halo nevi; Lines of blaschko; Mosaicism; Segmental; Segmental vitiligo; Surgical treatment; Vitiligo