Exploring the bioprospecting and biotechnological potential of white-rot and anaerobic Neocallimastigomycota fungi: peptidases, esterases, and lignocellulolytic enzymes.
Fungi constitute an invaluable natural resource for scientific research, owing to their diversity; they offer a promising alternative for bioprospecting, thus contributing to biotechnological advances. For a long time, extensive information has been exploited and fungal products have been tested as a source of natural compounds. In this context, enzyme production remains a field of interest, since it offers an efficient alternative to the hazardous processes of chemical transformations. Owing to their vast biodiversity and peculiar biochemical characteristics, two fungal categories, white-rot and anaerobic Neocallimastigomycota, have gathered considerable attention for biotechnological applications. These fungi are known for their ability to depolymerize complex molecular structures and are used in degradation of lignocellulosic biomass, improvement of animal feed digestibility, biogas and bioethanol production, and various other applications. However, there are only limited reports that describe proteolytic enzymes and esterases in these fungi and their synergistic action with lignocellulolytic enzymes on degradation of complex polymers. Thus, in this minireview, we focus on the importance of these organisms in enzyme technology, their bioprospecting, possibility of integration of their enzyme repertoire, and their prospects for future biotechnological innovation.
Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Av. do Café, s/n Campus Universitário da USP, Ribeirão Preto, São Paulo, 14040-903, Brazil. rds.roni@yahoo.com.br.
Ronivaldo Rodrigues
RR
da Silva
Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Av. do Café, s/n Campus Universitário da USP, Ribeirão Preto, São Paulo, 14040-903, Brazil.
Rafael
R
Pedezzi
Instituto Federal de Educação, Ciência e Tecnologia do Espírito Santo (IFES), Nova Venécia, ES, Brazil.
Tatiane Beltramini
TB
Souto
D000693:Anaerobiosis; D056804:Biofuels; D018533:Biomass; D065132:Bioprospecting / Q000379:methods*; D001709:Biotechnology / Q000379:methods* / Q000639:trends; D004950:Esterases / Q000378:metabolism; D008031:Lignin / Q000378:metabolism; D055136:Neocallimastigomycota / Q000201:enzymology* / Q000378:metabolism; D010447:Peptide Hydrolases / Q000378:metabolism; D011108:Polymers / Q000378:metabolism; D012988:Soil Microbiology; D014934:Wood / Q000382:microbiology
D056804:Biofuels; D011108:Polymers; C036909:lignocellulose; D008031:Lignin; D004950:Esterases; D010447:Peptide Hydrolases
Anaerobic Neocallimastigomycota; Biotechnology; Enzymes; White-rot; Wood-decay fungi