Two new terpenoids from Kalimeris indica.
A new nor-sesquiterpene kalimeristone A (1), a new nor-triterpenoid kalimerislactone B (2) and eight known compounds 7-hydroxy-4'methoxyisoflavone (3), episyringaresinol (4), epipinoresinol (5), rhamnetin (6), vanillin (7), p-hydroxybenzaldehyde (8), syringic acid (9) and 3, 4-dihydroxybenzaldehyde (10) were isolated from the herbs of Kalimeris indica. The structures of these compounds were elucidated using spectroscopic techniques, such as NMR and MS. All of the compounds were isolated from this genus for the first time. The cytotoxicities against four cancer cell lines were evaluated in vitro, but were inactive.
a School of Pharmacy, Anhui University of Chinese Medicine , Anhui Key Laboratory of Modern Chinese Materia Medica , Hefei , China.|b Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement , Hefei , P.R China.
Guo-Kai
GK
Wang
a School of Pharmacy, Anhui University of Chinese Medicine , Anhui Key Laboratory of Modern Chinese Materia Medica , Hefei , China.
Yang
Y
Yu
a School of Pharmacy, Anhui University of Chinese Medicine , Anhui Key Laboratory of Modern Chinese Materia Medica , Hefei , China.
Zheng
Z
Wang
a School of Pharmacy, Anhui University of Chinese Medicine , Anhui Key Laboratory of Modern Chinese Materia Medica , Hefei , China.
Bai-Xiang
BX
Cai
c Guang dong Provincial Key Laboratory of Applied Botany , South China Botanical Garden, Chinese Academy of Sciences , Guangzhou , China.
Zhong-Yu
ZY
Zhou
a School of Pharmacy, Anhui University of Chinese Medicine , Anhui Key Laboratory of Modern Chinese Materia Medica , Hefei , China.|b Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement , Hefei , P.R China.
Gang
G
Wang
a School of Pharmacy, Anhui University of Chinese Medicine , Anhui Key Laboratory of Modern Chinese Materia Medica , Hefei , China.|b Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement , Hefei , P.R China.
Jin-Song
JS
Liu
D019659:Asteraceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D002681:China; D006801:Humans; D015394:Molecular Structure; D064209:Phytochemicals / Q000737:chemistry / Q000302:isolation & purification; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification
D064209:Phytochemicals; D013729:Terpenes
Kalimeris indica; cytotoxicity; nor-sesquiterpene; nor-triterpenoid