Juvenile Granulosa Cell Tumor of the Testicle - Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining.
We report on a case of juvenile granulosa cell tumor of the testicle in a neonate, a rare testicular tumor in children. No genital ambiguity, anatomic abnormalities, nor sex chromosome aneuploidy was noted in this patient. In our case, despite positive staining for alpha-fetoprotein which is most consistent with yolk sac tumors, all clinical, gross anatomic, histologic, and other immunohistologic characteristics of the tumor remained consistent with the diagnosis of juvenile granulosa cell tumor. The alpha-fetoprotein positivity of the tumor remains unexplained.
Department of Pediatrics, Staten Island University-Northwell Health, Staten Island, NY, USA.
Melissa
M
Dundas
Department of Urology, Cornell University, New York, NY, USA; Department of Pediatrics, Staten Island University Hospital, Staten Island, NY, USA.
Mark
M
Horowitz
Department of Pediatrics, Staten Island University-Northwell Health, Staten Island, NY, USA.
Richard
R
Sidlow
Alpha fetoprotein; Immunohistochemistry; Juvenile granulosa cell tumor; Neonate; Testicle