Molecular characterization of Camelpox virus isolates from Bikaner, India: Evidence of its endemicity.
Camelpox is an important viral disease of camels, which may produce mild skin lesions or severe systemic infections. Camelpox virus (CMLV) isolates retrieved from an incidence of camelpox in camels at Bikaner, India were characterized on the basis of genotype and pathotype. Histopathological examination of the CMLV scab revealed intracytoplasmic-eosinophilic inclusion bodies. The phylogenetic analysis of all eight CMLV isolates for C18L gene nucleotide sequence revealed its clustering with its strains M-96 from Kazakhstan and CMS from Iran. The study will help to understand the transmission chain, pathobiology, and epidemiology of circulating CMLV strains. The full genome sequencing of some of the exemplary samples of CMLV is recommended in order to plan and implement a suitable control strategy.
National Research Center on Camel, Jorbeer, Bikaner, Rajasthan, 334001, India. Electronic address: dshsing04@gmail.com.
Shyam Singh
SS
Dahiya
Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, 781039, India.
Sachin
S
Kumar
National Research Center on Camel, Jorbeer, Bikaner, Rajasthan, 334001, India.
Sharat Chandra
SC
Mehta
National Research Center on Camel, Jorbeer, Bikaner, Rajasthan, 334001, India.
Raghvendar
R
Singh
National Research Center on Camel, Jorbeer, Bikaner, Rajasthan, 334001, India.
Kashi
K
Nath
National Research Center on Camel, Jorbeer, Bikaner, Rajasthan, 334001, India.
Shirish D
SD
Narnaware
National Research Center on Camel, Jorbeer, Bikaner, Rajasthan, 334001, India.
Fateh Chand
FC
Tuteja
D000818:Animals; D001483:Base Sequence; D002162:Camelus / Q000821:virology*; D007194:India / Q000453:epidemiology; D018155:Orthopoxvirus / Q000235:genetics* / Q000302:isolation & purification*; D010802:Phylogeny; D011213:Poxviridae Infections / Q000662:veterinary* / Q000821:virology; D012871:Skin Diseases / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology
Camelpox; Histopathology; Isolation; PCR; Phylogenetic