Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy).
BACKGROUND
Photobiomodulation, also referred to as low-level laser therapy (LLLT), has been studied and used for (among other diseases) the promotion of hair regrowth.
A clinical study was developed to define the physiologic effects that occur when the human hair follicle and surrounding tissue structures are exposed to laser light using a novel device that is fitted with an array of laser diode sources operating at 650 nm and placed inside a sports cap to promote discretion while in use. The study demonstrates that low-level laser treatment of the scalp every other day for 17 weeks using the HANDI-DOME LASER device is a safe and effective treatment for androgenetic alopecia in healthy females between the ages of 18 to 60 with Fitzpatrick skin Types I to IV and Ludwig-Savin Baldness Scale I-2 to II-2 baldness patterns. Subjects receiving LLLT at 650 nm achieved a 51% increase in hair counts as compared with sham-treated control patients in this multicenter randomized controlled trial.


CONCLUSIONS
These results suggest that the emerging technology of low-level laser therapy may play a potentially significant role in health care providers' armamentarium for the disease androgenic alopecia.
*Scottsdale Institute For Cosmetic Dermatology, Scottsdale, Arizona; †Capillus, Miami, Florida.
Shelly
S
Friedman
Patricia
P
Schnoor
D000293:Adolescent; D000328:Adult; D000505:Alopecia / Q000532:radiotherapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D028022:Low-Level Light Therapy; D008875:Middle Aged; D055815:Young Adult