The biomedical aspects of oral mucosal epithelial cell culture in mammals.
In recent years, there has been a growing interest in epithelial cell tissue culture, particularly oral mucosa and its application utilizing in vitro cell culture in medicine. This involves tests using animal models to better understand oral mucosa function, and the differences in its construction in various animal models. The use of buccal pouch mucosal cell culture provides insight into the processes of trans mucosal transport and regeneration of the oral epithelium. The processes associated with epithelium regeneration is the base for stem cell research and/or oral cancer investigation. These artificially cultured tissue equivalents are used in transplant surgery for the treatment of a variety of tissue dysfunctions, i.e. eye, esophagus, or urethra. In this review, the most recent results from studies carried out on in animal models, which may be applied in areas such as regenerative medicine and reconstructive surgery, were explored.
Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.
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A
Bryja
Department of Biomaterials and Experimental Dentistry, Poznan University of Medical Sciences, Poznan, Poland.
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M
Dyszkiewicz-Konwińska
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
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J
Budna
Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.
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W
Kranc
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
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A
Chachuła
Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.
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S
Borys
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
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Ciesiółka
Department of Dental Surgery, Poznan University of Medical Sciences, Poznan, Poland.
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J
Sokalski
Department of Biomaterials and Experimental Dentistry, Poznan University of Medical Sciences, Poznan, Poland.
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M
Prylinski
Institute of Veterinary Sciences, Poznan University of Life Sciences, Poland.
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D
Bukowska
Institute of Veterinary Sciences, Poznan University of Life Sciences, Poland.
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P
Antosik
Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.
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M
Bruska
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
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M
Nowicki
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
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M
Zabel
Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.|Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland.
B
B
Kempisty
D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D018929:Cell Culture Techniques / Q000379:methods*; D004847:Epithelial Cells / Q000166:cytology / Q000378:metabolism / Q000637:transplantation*; D004947:Esophagus / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D005123:Eye / Q000378:metabolism / Q000473:pathology; D015870:Gene Expression; D006801:Humans; D007633:Keratins / Q000235:genetics / Q000378:metabolism; D009061:Mouth Mucosa / Q000166:cytology / Q000378:metabolism / Q000637:transplantation*; D009062:Mouth Neoplasms / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods*; D012038:Regeneration / Q000502:physiology; D044968:Regenerative Medicine / Q000379:methods*; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism; D014182:Transplantation, Autologous; D014521:Urethra / Q000378:metabolism / Q000473:pathology / Q000601:surgery
D015415:Biomarkers; D007633:Keratins