Psychological resilience aspects that mediate the depressive effects of urinary incontinence in prostate cancer survivors 10 years after treatment with radiation and hormone ablation.
Repeated surveys of prostate cancer (PCa) patients indicate that their prevalence of depression is well above that for their non-PCa peers. Although standard first-line treatments for depression are only about 35% effective, some recent comments have suggested that a focus upon the possible correlates (factors that aggravate or mediate depression) might help improve treatment efficacy. To investigate this issue, 144 10 year PCa survivors were asked about the frequency of urinary incontinence, a common side effect of some PCa treatments. The 53 patients who suffered urinary incontinence had significantly higher depression scores on the Zung Self-rating Depression Scale than those patients who did not report urinary incontinence. Using mediation analysis, patients' psychological resilience (PR) significantly mediated the depressive effects of urinary incontinence, but those effects were confined to just one of the five components of PR-a sense of control over the things that happen to oneself. Implications for treatment models of psychosocial oncology support for PCa survivors are discussed.
a Brain-Behaviour Research Group , University of New England , Armidale , New South Wales , Australia.
Christopher F
CF
Sharpley
b Centre for Autism Spectrum Disorders , Bond University , Gold Coast , Queensland , Australia.
Vicki
V
Bitsika
a Brain-Behaviour Research Group , University of New England , Armidale , New South Wales , Australia.|c Genesiscare , Tugun , Queensland , Australia.
David R H
DRH
Christie
d School of Medicine and Public Health , University of Newcastle , Newcastle , New South Wales , Australia.
Rosemary
R
Bradford
d School of Medicine and Public Health , University of Newcastle , Newcastle , New South Wales , Australia.
Allison
A
Steigler
d School of Medicine and Public Health , University of Newcastle , Newcastle , New South Wales , Australia.
James W
JW
Denham
D000368:Aged; D000369:Aged, 80 and over; D000726:Androgen Antagonists / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003863:Depression / Q000453:epidemiology / Q000523:psychology*; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000523:psychology* / Q000532:radiotherapy; D055500:Resilience, Psychological; D017741:Survivors / Q000523:psychology* / Q000706:statistics & numerical data; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000453:epidemiology / Q000523:psychology*
D000726:Androgen Antagonists; D018931:Antineoplastic Agents, Hormonal
cancer; depression; prostate; resilience