Endoscopic Management of Early Gastric Adenocarcinoma and Preinvasive Gastric Lesions.
Early gastric cancer (ECG) can be difficult to diagnose endoscopically. Endoscopists should be familiar with subtle changes and endoscopic features of EGC. Chromoendoscopy and image-enhanced endoscopy improve diagnostic accuracy and facilitate endoscopic resection. Endoscopic submucosal dissection is a preferred endoscopic technique for resection of EGC and offers a comparable overall survival to surgical resection. Endoscopic management of benign gastric epithelial polyps (fundic gland polyps, hyperplastic polyps, and gastric adenoma) depends on patient symptomatology, patient's comorbidities (eg, familial syndromes), lesions' characteristics, and risk of malignant transformation. This article provides an overview of endoscopic management of EGC and common premalignant gastric lesions.
Division of Gastroenterology and Hepatology, Johns Hopkins Medicine, Johns Hopkins Medical Institutions, 4940 Eastern Avenue, A Building, 5th Floor, Baltimore, MD 21224, USA. Electronic address: sngamru1@jh.edu.
Saowanee
S
Ngamruengphong
Endoscopy Division, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Seiichiro
S
Abe
Endoscopy Division, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Ichiro
I
Oda
D000230:Adenocarcinoma / Q000175:diagnosis / Q000601:surgery*; D000236:Adenoma / Q000175:diagnosis / Q000601:surgery; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D004396:Coloring Agents; D055088:Early Detection of Cancer; D005773:Gastroscopy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology; D007417:Intestinal Polyps / Q000175:diagnosis / Q000601:surgery; D062048:Narrow Band Imaging / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000601:surgery*
D004396:Coloring Agents
Detection; Early gastric cancer; Endoscopic submucosal dissection; Gastric cancer; Narrow band imaging; Screening; Stomach neoplasms