18F-Fluorocholine PET/CT, Brain MRI, and 5-Aminolevulinic Acid for the Assessment of Tumor Resection in High-Grade Glioma.
High-grade glioma is a very aggressive and infiltrative tumor in which complete resection is a chance for a better outcome. We present the case of a 57-year-old man with a brain lesion suggestive of high-grade glioma. Brain MRI and F-fluorocholine PET/CT were performed previously to plan the surgery. Surgery was microscope assisted after the administration of 5-aminolevulinic acid. Postsurgery brain MRI and PET were blind evaluated to the surgery results and reported as probably gross total resection.
From the Departments of *Nuclear Medicine, †Radiology, and ‡Neurosurgery, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain.
Ana María
AM
García Vicente
Fátima
F
Jiménez Aragón
Maikal
M
Villena Martín
German Andrés
GA
Jiménez Londoño
Jose María
JM
Borrás Moreno
D000622:Aminolevulinic Acid / Q000494:pharmacology*; D001921:Brain / Q000000981:diagnostic imaging* / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002794:Choline / Q000031:analogs & derivatives*; D005910:Glioma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D000072078:Positron Emission Tomography Computed Tomography
C514960:fluorocholine; D000622:Aminolevulinic Acid; D002794:Choline