N2gas egress from patients' airways during LN2spray cryotherapy.
Spray cryotherapy using liquid nitrogen (LN2) is a general surgical tool used to ablate benign or malignant lesions. Adequate egress of the gaseous nitrogen (N2) generated during this process must be provided for safe use when LN2is used within the body rather than topically. When delivered to either the gastrointestinal tract (requiring active venting via a suction tube) or body cavities open to room barometric pressure (such as lung airways) allowing for passive venting, the N2gas generated from the boiling process must be evacuated. This work will examine the egress of N2during procedures requiring passive venting from human airways undergoing liquid nitrogen spray cryotherapy. Venting characteristics for safe N2egress will be presented and discussed based on analytical modeling using fluid mechanics simulations and experimental studies of N2venting with laboratory and porcine models.
CSA Medical, Inc. 91 Hartwell Avenue, Lexington MA 02421, USA. Electronic address: joconnor@csamedical.com.
John P
JP
O'Connor
CSA Medical, Inc. 91 Hartwell Avenue, Lexington MA 02421, USA.
Brian M
BM
Hanley
CSA Medical, Inc. 91 Hartwell Avenue, Lexington MA 02421, USA.
Thomas I
TI
Mulcahey
CSA Medical, Inc. 91 Hartwell Avenue, Lexington MA 02421, USA.
Ellen E
EE
Sheets
CSA Medical, Inc. 91 Hartwell Avenue, Lexington MA 02421, USA.
Kacey W
KW
Shuey
D017679:Cryotherapy / Q000379:methods*; D006801:Humans; D057446:Hydrodynamics; D008168:Lung / Q000378:metabolism*; D008954:Models, Biological; D009584:Nitrogen / Q000378:metabolism*
D009584:Nitrogen
Cryoablation; LN(2) spray cryotherapy; N(2) egress; Passive venting