Case report: a case of eruptive collagenoma occurring in esophagus and intestine.
BACKGROUND
Eruptive collagenoma is a rare disease. All of the previously reported cases were located on the skin. Here we report such a case occurring in esophagus and intestine.


METHODS
Our patient is a Chinese woman. Two years ago, hundreds of small nodules were identified in her esophagus and intestine. The lesions were characterized by thickened hyalinized collagen fibers and haphazard neoplastic stellate cells. The tumor cells showed generally positive for vimentin and negative for h-CALD, CD34, desmin, CD163, AE1/AE3, CK7 and CK20. The nodules were blue with Masson Trichrome stain. The clinicopathological, immunohistochemical and histochemical features of the tumor were consistent with eruptive collagenoma. The patient was not given specific treatment after diagnosis, and a routine examination indicated that there was no progress for 2 years.


CONCLUSIONS
Hitherto, this is the first case of eruptive collagenoma to have been reported occurring in esophagus and intestine.
Department of Pathology, Yantai Affiliated Hospital of Binzhou Medical University, No. 717, Jinbu Street, Yantai, Shandong Province, 264100, China.
Ping
P
Gao
Department of Pathology, Yantai Affiliated Hospital of Binzhou Medical University, No. 717, Jinbu Street, Yantai, Shandong Province, 264100, China.
Lili
L
Jing
Department of Pathology, Yantai Affiliated Hospital of Binzhou Medical University, No. 717, Jinbu Street, Yantai, Shandong Province, 264100, China.
Hai
H
Huang
Department of Pathology, Yantai Affiliated Hospital of Binzhou Medical University, No. 717, Jinbu Street, Yantai, Shandong Province, 264100, China.
Cuiping
C
Zhang
Department of Pathology, Yantai Affiliated Hospital of Binzhou Medical University, No. 717, Jinbu Street, Yantai, Shandong Province, 264100, China. ytfyblk@163.com.
Junmei
J
Hao
D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D003095:Collagen Diseases / Q000378:metabolism / Q000473:pathology*; D003108:Colonic Diseases / Q000378:metabolism / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D004935:Esophageal Diseases / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006222:Hamartoma / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007077:Ileal Diseases / Q000378:metabolism / Q000473:pathology*; D007150:Immunohistochemistry
D015415:Biomarkers
Eruptive collagenoma; Esophagus; Intestine