Detection of combined procalcitonin and c-reactive protein applied in the diagnosis of bacterial infections.
In recent years, procalcitonin and C-reactive protein have been used as important indexes in the detection of inflammation. In order to analyze the combined detection of procalcitonin and C-reactive protein in infected patients, 57 subjects in the Clinical Laboratory of Zhengzhou Maternal and Child Health Hospital with a bacterial infection were selected as the observation group. Correspondingly, 57 non-infected subjects were selected for the control group. The procalcitonin and C-reactive protein levels in the included cases were analyzed and compared by extracting peripheral blood. The results showed that the two indexes of C-reactive protein (46.13±8.24 mg/L) and procalcitonin (6.61±3.45 ug/L) of the observation group were significantly higher than those of the control group (P less than 0.05). The positive rates of C-reactive protein (71.93%) and procalcitonin (91.23%) of the observation group were significantly higher than those of the control group (P less than0.05). Within the observation group, the C-reactive protein and procalcitonin levels in the infected patients after 2 and 3 days of treatment, decreased significantly (P less than 0.05). This study indicates that the combined detection of procalcitonin and C-reactive protein in patients with bacterial infections is effective and can be used in clinical settings.
Clinical Laboratory, Women and Infants Hospital of Zhengzhou, Zhengzhou, China.
Y L
YL
Li
Clinical Laboratory, Women and Infants Hospital of Zhengzhou, Zhengzhou, China.
L C
LC
Zhai
Clinical Laboratory, Women and Infants Hospital of Zhengzhou, Zhengzhou, China.
J H
JH
Ji
Clinical Laboratory, Women and Infants Hospital of Zhengzhou, Zhengzhou, China.
L Y
LY
Liu
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D002116:Calcitonin / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D012372:ROC Curve; D018805:Sepsis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D012772:Shock, Septic / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D014552:Urinary Tract Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology
D000900:Anti-Bacterial Agents; D015415:Biomarkers; D002116:Calcitonin; D002097:C-Reactive Protein