West Nile Virus Seroprevalence, Connecticut, USA, 2000-2014.
West Nile virus (WNV) infection is mainly asymptomatic but can be severe in elderly persons. As part of studies on immunity and aging in Connecticut, USA, we detected WNV seroconversion in 8.5% of nonimmunosuppressed and 16.8% of immunosuppressed persons. Age was not a significant seroconversion factor. Our findings suggest that immune factors affect seroconversion.
Megan E
ME
Cahill
Yi
Y
Yao
David
D
Nock
Philip M
PM
Armstrong
Theodore G
TG
Andreadis
Maria A
MA
Diuk-Wasser
Ruth R
RR
Montgomery
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D003237:Connecticut / Q000453:epidemiology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D014901:West Nile Fever / Q000097:blood*
D000914:Antibodies, Viral
Connecticut; United States; West Nile virus; aging; immune response; seroconversion; vector-borne infections; viral susceptibility; viruses