The use of non-steroidal anti-inflammatory drugs in neurological diseases.
Non-steroidal anti-inflammatory drugs (NSAIDs) have been in use for many years and constitute a large part of prescriptions issued in daily practice. Although NSAIDs are used for many diseases in neurology, they have also been tested as a new therapeutic option for various other diseases. While their effects on headache and cerebrovascular diseases are well known, little is known about their impact on neurodegenerative diseases. This review discusses the use, effects and safety of NSAIDs in neurological diseases.
Department of Neurology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. Electronic address: mterzi@omu.edu.tr.
Murat
M
Terzi
Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Gamze
G
Altun
Department of Neurology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
Sedat
S
Şen
Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Adem
A
Kocaman
Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Arife Ahsen
AA
Kaplan
Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Kıymet Kübra
KK
Yurt
Department of Histology and Embryology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Süleyman
S
Kaplan
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D006801:Humans; D019636:Neurodegenerative Diseases / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal
Cyclooxygenase inhibition; Neurodegeneration; Neuroinflammation; Non-steroidal anti-inflammatory drugs; Prostaglandins