Gut Microbiota: A New Marker of Cardiovascular Disease.
Cardiovascular disease (CVD) continues to be the major cause of death in the developed countries. Moreover, the cardiovascular risk factors leading towards the development of CVD, mainly type 2 diabetes and obesity, are on the rise. The current preventive and therapeutic management, centred on the control of traditional risk factors, is clearly not enough to stop this pandemic. Therefore, the search for new biomarkers in CVD is a priority in most clinical research programs. Currently, interest in gut microbiota has peaked due to its association with cardiovascular and non-cardiovascular diseases. The present review considers the current situation regarding the influence of gut microbiota on CVD and particularly, its influence on the main traditional risk factors that lead to CVD, such as lipids, diabetes, hypertension and obesity.
Lipids and Atherosclerosis Unit, IMIBIC/Hospital Universitario Reina Sofía/Universidad de Córdoba and Ciber Fisiopatologia Obesidad y Nutricion, Instituto Salud Carlos III. Spain.
Antonio
A
Garcia-Rios
Lipids and Atherosclerosis Unit, IMIBIC/Hospital Universitario Reina Sofía/Universidad de Córdoba and Ciber Fisiopatologia Obesidad y Nutricion, Instituto Salud Carlos III. Spain.
Jose David
JD
Torres-Peña
Lipids and Atherosclerosis Unit, IMIBIC/Hospital Universitario Reina Sofía/Universidad de Córdoba and Ciber Fisiopatologia Obesidad y Nutricion, Instituto Salud Carlos III. Spain.
Francisco
F
Perez-Jimenez
Reina Sofia University Hospital, Lipids and Atherosclerosis Research Unit. Avda. Menéndez Pidal, s/n. 14004 Córdoba. Spain.
Pablo
P
Perez-Martinez
D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism; D000069196:Gastrointestinal Microbiome / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism; D050356:Lipid Metabolism / Q000502:physiology; D009765:Obesity / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism; D012307:Risk Factors
D015415:Biomarkers
Microbiota; cardiovascular disease.; diabetes; hypertension; lipid metabolism; obesity