DNA Compass: a secure, client-side site for navigating personal genetic information.
BACKGROUND
Millions of individuals have access to raw genomic data using direct-to-consumer companies. The advent of large-scale sequencing projects, such as the Precision Medicine Initiative, will further increase the number of individuals with access to their own genomic information. However, querying genomic data requires a computer terminal and computational skill to analyze the data-an impediment for the general public.


RESULTS
DNA Compass is a website designed to empower the public by enabling simple navigation of personal genomic data. Users can query the status of their genomic variants for over 1658 markers or tens of millions of documented single nucleotide polymorphisms (SNPs). DNA Compass presents the relevant genotypes of the user side-by-side with explanatory scientific resources. The genotype data never leaves the user's computer, a feature that provides improved security and performance. More than 12 000 unique users, mainly from the general genetic genealogy community, have already used DNA Compass, demonstrating its utility.


METHODS
DNA Compass is freely available on https://compass.dna.land .


BACKGROUND
yaniv@cs.columbia.edu.
New York Genome Center, New York, NY, USA.
Charles
C
Curnin
New York Genome Center, New York, NY, USA.
Assaf
A
Gordon
New York Genome Center, New York, NY, USA.|Department of Computer Science, Fu Foundation School of Engineering, Columbia University, New York, NY, USA.|Center for Computational Biology and Bioinformatics, Columbia University, New York, NY, USA.
Yaniv
Y
Erlich
D030661:Genetic Privacy; D015894:Genome, Human; D006801:Humans; D016247:Information Storage and Retrieval; D020641:Polymorphism, Single Nucleotide; D057285:Precision Medicine; D017422:Sequence Analysis, DNA / Q000295:instrumentation*; D012984:Software