[Correlation between chronic constipation and colorectal neoplasms].
The correlation between chronic constipation and colorectal neoplasms has been arousing wide interest. There have been a number of domestic and international epidemiological and clinical researches focusing on this issue. Based on these researches, the correlation between constipation and colorectal neoplasms was studied from three aspects: constipation and colorectal polyps; constipation and colorectal cancer; melanosis coli (MC), laxatives and colorectal neoplasms. We find that constipation can significantly increase the incidence of colorectal polyps and constipation does not significantly increase the incidence of colorectal cancer but is one of the risk factors for colorectal cancer. In addition, MC, laxatives and the incidence of colorectal polyps are also closely correlated. Given the fact that colorectal polyps are precancerous lesions, patients with long-term constipation should take less anthraquinone laxatives, and those with colorectal polyps should be followed up periodically.
Department of General Surgery, Center of Constipation Diagnosis and Treatment, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China. LBH57268@163.com.
Baohua
B
Liu
D000880:Anthraquinones / Q000009:adverse effects*; D003108:Colonic Diseases / Q000150:complications; D003111:Colonic Polyps / Q000453:epidemiology*; D015179:Colorectal Neoplasms / Q000453:epidemiology*; D003248:Constipation / Q000150:complications*; D006801:Humans; D015994:Incidence; D054368:Laxatives / Q000009:adverse effects*; D008548:Melanosis / Q000150:complications / Q000453:epidemiology; D012307:Risk Factors
D000880:Anthraquinones; D054368:Laxatives