Transcatheter aortic valve implantation with the self-expandable venus A-Valve and CoreValve devices: Preliminary Experiences in China.
BACKGROUND
Transcatheter aortic valve implantation (TAVI) has been demonstrated to be an effective alternative to surgical aortic valve replacement (SAVR) in patients with aortic stenosis who are deemed high risk or inoperable. Currently, TAVI procedures in China mostly make use of the domestic Venus A-Valve and the CoreValve; however, there is no data on their comparative performance.


METHODS
Consecutive patients undergoing TAVI with the aforementioned devices were included. The outcomes were reported according to the Valve Academic Research Consortium-2 (VARC) definitions.


RESULTS
A total of 54 TAVI procedures were performed, 27 with the CoreValve and the other 27 with the Venus A-Valve. An additional valve was required in 4 (14.8%) and 3 (11.1%) patients, and the VARC-2 device success rates were 81.5 and 85.2%, respectively. The incidences of common complications were similar, except for the significantly less frequent pacemaker insertion in the Venus A-Valve group (7.4 vs. 37.0%, P = 0.03). Within 30 days, 2 (3.7%) patients died, 1 in each group, and both had a bicuspid aortic valve (BAV). No other serious complications, such as annular rupture, coronary obstruction and aortic dissection, occurred in the 32 BAV patients treated with the Venus A-Valve (14) or the CoreValve (18). After 2-years of follow-up, there was no significant difference between CoreValve group and Venus-A group (11.1 vs. 7.4%, P = 0.64).


CONCLUSIONS
TAVI with the domestic Venus A-Valve is feasible, safe, and can produce favorable short-term outcomes comparable to those with the CoreValve in inoperable or high-risk patients with tricuspid and bicuspid aortic valve stenosis. © 2017 Wiley Periodicals, Inc.
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Yan-Biao
YB
Liao
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Zhen-Gang
ZG
Zhao
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Xin
X
Wei
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Yuan-Ning
YN
Xu
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Zhi-Liang
ZL
Zuo
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Yi-Jian
YJ
Li
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Ming-Xia
MX
Zheng
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Yuan
Y
Feng
Department of Cardiology, West China Hospital, Sichuan University, People's Republic of China.
Mao
M
Chen
D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods / Q000401:mortality; D002681:China; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D013997:Time Factors; D016896:Treatment Outcome
CoreValve; Venus-A Valve; aortic stenosis; transcatheter aortic valve implantation