Female Functional Constipation Is Associated with Overactive Bladder Symptoms and Urinary Incontinence.
This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2,p= 0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%,p= 0.001, and 31.7 versus 7.1%,p< 0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125,p= 0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227,p= 0.005 and OR = 4.753,p= 0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.
Department of Urology, Saiseikai Central Hospital, Tokyo, Japan.
Takahiro
0000-0003-4479-7835
T
Maeda
Department of Internal Medicine, Saiseikai Central Hospital, Tokyo, Japan.
Masuomi
M
Tomita
Department of Internal Medicine, Saiseikai Central Hospital, Tokyo, Japan.
Atsushi
0000-0003-2720-7514
A
Nakazawa
Department of Internal Medicine, Saiseikai Central Hospital, Tokyo, Japan.
Gen
G
Sakai
Department of Internal Medicine, Saiseikai Central Hospital, Tokyo, Japan.
Shinsuke
S
Funakoshi
Department of Urology, Saiseikai Central Hospital, Tokyo, Japan.
Akari
A
Komatsuda
Department of Urology, Saiseikai Central Hospital, Tokyo, Japan.
Yujiro
Y
Ito
Department of Urology, Saiseikai Central Hospital, Tokyo, Japan.
Hirohiko
H
Nagata
Department of Internal Medicine, Saiseikai Central Hospital, Tokyo, Japan.
Nobuhiro
N
Tsukada
Department of Urology, Saiseikai Central Hospital, Tokyo, Japan.
So
S
Nakamura
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003248:Constipation / Q000150:complications / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D012720:Severity of Illness Index; D053201:Urinary Bladder, Overactive / Q000150:complications / Q000503:physiopathology*; D014549:Urinary Incontinence / Q000150:complications / Q000503:physiopathology*; D014554:Urination / Q000502:physiology