Pseudomonas oryzihabitans sepsis in a 1-year-old child with multiple skin rashes: a case report.
BACKGROUND
Pseudomonas oryzihabitans is a Pseudomonas bacterial organism rarely implicated in human infections. The bacterium has been isolated in a few reported cases of neurosurgical infections and patients with end-stage cirrhosis, sickle cell disease, and community-acquired urinary tract infections. Limited information exists in developing countries, however, because of the lack of advanced microbiological tools for identification and characterization of this bacterium. This case report describes the isolation of a rare Pseudomonas bacterium in a patient presenting with sepsis and skin infection.


METHODS
A 1-year-old girl was presented to a hospital in the northeastern part of Ghana with a 1-week history of pustular rashes on her scalp and neck, which occasionally ruptured, along with discharge of yellowish purulent fluid. The child is of Mole-Dagbon ethnicity and hails from the northern part of Ghana. Pseudomonas oryzihabitans was identified in the patient's blood culture using the 16S ribosomal deoxyribonucleic acid sequencing technique. The rash on the patient's scalp and skin resolved after continuous treatment with gentamicin while her condition improved clinically.


CONCLUSIONS
This finding suggests the potential of this bacterium to cause disease in unsuspected situations and emphasizes the need to have evidence for the use of the appropriate antibiotic in clinical settings, particularly in rural settings in Africa. It also brings to the fore the unreliability of conventional methods for identification of Pseudomonas bacteria in clinical samples and thus supports the use of 16S ribosomal deoxyribonucleic acid in making the diagnosis.
Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Michael
M
Owusu
Department of Global Health, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. owusudabo@kccr.de.
Ellis
E
Owusu-Dabo
Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Godfred
G
Acheampong
Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Isaac
I
Osei
Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
John
J
Amuasi
Agogo Presbyterian Hospital, PO Box 27, Agogo, Ashanti Region, Ghana.
Nimako
N
Sarpong
Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Augustina
A
Annan
Institute of Plant and Microbial Biology, Academia Sinica, 128 Section 2, Academia Road, Nankang, Taipei, 11529, Taiwan.
Hsin-Ying
HY
Chiang
Institute of Plant and Microbial Biology, Academia Sinica, 128 Section 2, Academia Road, Nankang, Taipei, 11529, Taiwan.
Chih-Horng
CH
Kuo
Department of Epidemiology, International Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.
Se Eun
SE
Park
Department of Epidemiology, International Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.
Florian
F
Marks
Department of Clinical Microbiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Yaw
Y
Adu-Sarkodie
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005076:Exanthema / Q000150:complications* / Q000382:microbiology; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D005869:Ghana; D006801:Humans; D007223:Infant; D009333:Neck / Q000382:microbiology / Q000473:pathology*; D011549:Pseudomonas / Q000145:classification / Q000302:isolation & purification*; D011552:Pseudomonas Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D012336:RNA, Ribosomal, 16S; D012535:Scalp / Q000382:microbiology / Q000473:pathology*; D018805:Sepsis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D012336:RNA, Ribosomal, 16S
16S ribosomal DNA; Case report; Pseudomonas oryzihabitans; Sepsis; Skin infections