Graves' Ophthalmopathy in a Paediatric Population.
BackgroundGraves' disease is an autoimmune disorder leading to hyperthyroidism. It is often associated with ophthalmic manifestations. Graves' disease is reported to be rare in the paediatric population.Patients and MethodsWe performed a retrospective analysis on all patients diagnosed with ophthalmopathy related to Graves' disease at a paediatric age (less than 18 years old) in our institution between 2004 and 2015.ResultsEight patients were identified: 6 females and 2 males. The median age at diagnosis was 11.5 years (range 3-16). Ophthalmic signs were: proptosis (6/8), superficial punctate keratitis (5/8), eyelid retraction (4/8), lagophthalmos (2/8), and oculomotor dysfunction (2/8). No patients showed signs of complication such as ocular hypertension or compressive optic neuropathy. Orbital decompression was performed in one patient in a non-emergency setting.ConclusionOphthalmic involvement in Graves' disease is rarely encountered in paediatric patients. Ophthalmologists should be aware of this entity to ensure that patients with thyroid dysfunction are identified at an early point in time.
Oculoplastic surgery unit, Jules Gonin Eye Hospital, University of Lausanne, Switzerland.
Y
Y
Sadeghi
Oculoplastic surgery unit, Jules Gonin Eye Hospital, University of Lausanne, Switzerland.
A
A
Obéric
Oculoplastic surgery unit, Jules Gonin Eye Hospital, University of Lausanne, Switzerland.
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G
Theintz
Oculoplastic surgery unit, Jules Gonin Eye Hospital, University of Lausanne, Switzerland.
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M
Hamédani
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D005128:Eye Diseases / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D049970:Graves Ophthalmopathy / Q000175:diagnosis* / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008297:Male; D012307:Risk Factors; D013557:Switzerland / Q000453:epidemiology