The Content of Plasma Selenium in Early Admitted Septic Patients.
OBJECTIVE
Selenium depletion has been reported in critical illness correlates with an increase in mortality and morbidity. In this study, we aimed to access the selenium plasma levels of septic patients early at the Intensive Care Unit (ICU) admission in order to compare with reference range.


METHODS
We conducted a cross-sectional study in a university affiliated hospital aiming to assess the early plasma level of selenium in ICU admitted patients. eighty patients diagnoses with sepsis were included and considered for characteristic evaluation, monitoring criteria assessment and also blood sampling. All blood sampling was performed during 48 hours of the ICU admission in order to determined the plasma Selenium level by atomic absorption method.


RESULTS
The mean plasma levels of selenium in male and female was 98.14 ± 23.52 and 78.1 ± 24.46 μ/L, respectively. Although selenium plasma levels was higher in the ICU male patients significantly, both had near normal range (80 μ/L).


CONCLUSIONS
In this study we found that in early admitted Iranian ICU patients in Tehran, selenium deficiency has not routinely seen but probably will happen during ICU hospitalization.
Critical Care Department, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Omid Moradi
OM
Moghaddam
Critical Care Department, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mohammad Niakan
MN
Lahiji
Department of Clinical Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran.
Azadeh
A
Moghaddas
Department of Clinical Pharmacy, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Maryam
M
Farasatinasab
Department of Clinical Pharmacy, Colorectal Research Center, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Somayyeh
S
Nasiripour
Critical ill patients; Selenium; intensive care unit; sepsis