Fluid-Structure Interaction in Abdominal Aortic Aneurysm: Effect of Modeling Techniques.
In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics and wall mechanics was compared with its simplified techniques, that is, computational fluid dynamics (CFD) or computational solid stress (CSS) model. Results demonstrated that CFD exhibited relatively smaller vortexes and tends to overestimate the fluid wall shear stress, compared to FSI. On the contrary, the minimal differences in wall stresses and deformation were observed between FSI and CSS models. Furthermore, it was found that the accuracy of CSS prediction depends on the applied pressure profile for the aneurysm sac. A large pressure drop across AAA usually led to the underestimation of wall stresses and thus the AAA rupture. Moreover, the assumed isotropic AAA wall properties, compared to the anisotropic one, will aggravate the difference between the simplified models with the FSI approach. The present work demonstrated the importance of modeling techniques on predicting the blood flow dynamics and wall mechanics of the AAA, which could guide the selection of appropriate modeling technique for significant clinical implications.
School of Civil Engineering and Architecture, Xiamen University of Technology, Xiamen, China; Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588-0656, USA.
Shengmao
S
Lin
Department of Interventional Radiology, The First Affiliated Hospital, Zhengzhou University, Henan Province, China.
Xinwei
X
Han
Department of Interventional Radiology, The First Affiliated Hospital, Zhengzhou University, Henan Province, China.
Yonghua
Y
Bi
Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588-0656, USA.
Siyeong
S
Ju
Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588-0656, USA; Nebraska Center for Materials and Nanoscience, Lincoln, NE 68588-0656, USA.
Linxia
0000-0003-2637-0299
L
Gu
D017544:Aortic Aneurysm, Abdominal / Q000503:physiopathology*; D001019:Aortic Rupture / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008955:Models, Cardiovascular