Management of Orbital Involvement in Sinonasal and Ventral Skull Base Malignancies.
The orbit may be frequently involved by sinonasal or ventral skull base malignancy. This involvement bodes a poorer prognosis for survival. Multimodality therapy with surgery and radiation therapy is usually attempted to optimize local control and overall survival. Oncologic surgical resection with negative margins is critical to local control and survival. In the past, any involvement of the orbit was deemed to necessitate orbital sacrifice. However, contemporary studies show that in carefully selected cases, orbital preservation does not adversely impact survival. In addition, novel reconstructive techniques can help minimize complications and optimize functional and aesthetic outcomes.
Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic, 5777 East Mayo Bouelvard, Phoenix, AZ 85054, USA.
Gregory S
GS
Neel
Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic, 5777 East Mayo Bouelvard, Phoenix, AZ 85054, USA.
Thomas H
TH
Nagel
Section of Neuroradiology, Department of Radiology, Mayo Clinic, 5777 East Mayo Bouelvard, Phoenix, AZ 85054, USA.
Joseph M
JM
Hoxworth
Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic College of Medicine, Mayo Clinic, 5777 East Mayo Bouelvard, Phoenix, AZ 85054, USA. Electronic address: Lal.Devyani@mayo.edu.
Devyani
D
Lal
D018304:Esthesioneuroblastoma, Olfactory / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008545:Melanoma / Q000473:pathology; D009915:Orbit / Q000473:pathology* / Q000601:surgery*; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000009:adverse effects*; D019291:Skull Base / Q000601:surgery; D019292:Skull Base Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed
Endoscopic resection; Orbit; Orbit preservation; Orbital clearance; Orbital exenteration; Orbital invasion; Orbital sacrifice; Sinonasal malignancy