Sex Differences in the Clinical Features, Risk Factors, and Outcomes of Intracerebral Hemorrhage: a Large Hospital-based Stroke Registry in China.
Intracerebral hemorrhage (ICH) is common in China. However, the sex differences in clinical features, risk factors, and outcomes of ICH remain controversial. Between 2005 and 2014, we recruited patients with primary ICH in Tianjin, China, and evaluated sex differences in clinical features, risk factors, and outcomes at 3, 12, and 36 months after ICH. The 1,325 patients included 897 men (67.7%) and 428 women (32.3%). The mean age at ICH onset was younger among men (59.14 years) than among women (63.12 years, P < 0.001). Men were more likely to have a hematoma in the basal ganglia, while women were more likely to have one in the thalamus. Women had higher frequencies of urinary tract infections, diabetes mellitus, cardiovascular diseases, and obesity. Men had a greater risk of death at 3 months after ICH. However, no sex differences were observed for mortality at 12 and 36 months after ICH or for recurrence and dependency at 3, 12, and 36 months after ICH. These findings suggested that it crucial to strengthen management of AF and complications in patients with ICH, especially management of blood pressure in men for reducing the mortality rates and the burden of ICH in China.
Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China. sycahh@126.com.|Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Disease, Tianjin, China. sycahh@126.com.
Yonghong
Y
Xing
Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China. tjhhazp@sina.com.|Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Disease, Tianjin, China. tjhhazp@sina.com.
Zhongping
Z
An
Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.|Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Disease, Tianjin, China.
Xianghui
X
Zhang
Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.|Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Disease, Tianjin, China.
Ning
N
Yu
Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.|Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Disease, Tianjin, China.
Wenjuan
W
Zhao
Department of Epidemiology, Tianjin Neurological Institute & Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Xianjia
X
Ning
Department of Epidemiology, Tianjin Neurological Institute & Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Jinghua
J
Wang
D000367:Age Factors; D002543:Cerebral Hemorrhage / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology*; D002681:China / Q000453:epidemiology; D006761:Hospitals; D006801:Humans; D012042:Registries; D012307:Risk Factors; D012737:Sex Factors; D016019:Survival Analysis