Oral inverted ductal papilloma: not related to HPV.
Oral inverted ductal papilloma (OIDP) is a rare, nonrecurrent,benign lesion of salivary glands. The etiologyis still poorly understood; the correlation with humanpapilloma virus (HPV) is controversial. Herein wepresent a 74-year-old man with a tumor in lower lip.Incisional biopsy was performed and the histologicaldiagnosis was OIDP. Inno-LiPA assay, based onpolymerase chain reaction and in situ hybridizationwas used to assess for HPV with no detection of viralDNA. Surgical excision was performed without anyrecurrences after two years of follow-up.
Alan Motta
AM
Do Canto
Florence Zumbaio
FZ
Mistro
Sergio
S
Kignel
Fabiana
F
Martins
Michelle
M
Palmieri
of Virology, Instituto de Medicina Tropical de São Paulo - Universidade de São Paulo, São Paulo, SP, Brazil. pbraz@usp.br.
Paulo Henrique
PH
Braz-Silva
D000368:Aged; D006801:Humans; D008046:Lip; D008297:Male; D018308:Papilloma, Inverted / Q000175:diagnosis* / Q000473:pathology / Q000821:virology; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000821:virology; D012468:Salivary Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000821:virology; D012470:Salivary Glands, Minor