Kaposiform Hemangioendothelioma Presenting as Hydrops Fetalis.
We describe the case of a 33-week preterm infant who developed nonimmune hydrops fetalis secondary to a kaposiform hemangioendothelioma (KHE). The tumor was successfully treated with vincristine, prednisone, ticlopidine, and aspirin. KHE can be an unusual cause of hydrops fetalis; in such cases, diagnosis can be challenging since generalized edema can obscure KHE.
Section of Neonatology, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Elena
E
Sobrino-Fernández
Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Minia
http://orcid.org/0000-0002-4638-2265
M
Campos-Domínguez
Section of Neonatology, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Rebeca
R
Gregorio-Hernández
Section of Pediatric Oncology, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Jorge
J
Huerta-Aragonés
Section of Pediatric Oncology, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Cristina
C
Beléndez-Bieler
Section of Pediatric Radiology, Department of Radiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Ángel
Á
Lancharro-Zapata
Section of Neonatology, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
María Luisa
ML
Franco-Fernández
Section of Neonatology, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Belén
B
Bernardo-Atienza
Section of Neonatology, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Manuel
M
Sánchez-Luna
D000284:Administration, Oral; D001241:Aspirin / Q000008:administration & dosage; D002585:Cesarean Section; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D005865:Gestational Age; D006390:Hemangioendothelioma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D006801:Humans; D015160:Hydrops Fetalis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D007234:Infant, Premature; D007262:Infusions, Intravenous; D059885:Kasabach-Merritt Syndrome / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D013988:Ticlopidine / Q000008:administration & dosage; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage*
D014750:Vincristine; D013988:Ticlopidine; D001241:Aspirin; D011241:Prednisone