Simultaneous monitoring of glucose and uric acid on a single test strip with dual channels.
The conventional test strip has usually only one electrochemical reaction channel, which requires two times figure punctures for the self-management of patients suffering from both diabetes and gout. Considering the large number of such patients and for the sake of reducing their pains, we report an enzymatic test strip which can simultaneously monitor glucose and uric acid (UA) with only one fingertip blood droplet. The proposed test strip is composed of dual channels. The glucose in blood is detected in the 1st channel above on the substrate and the UA is characterized in the 2nd channel located at the bottom of the substrate. The proposed design intensively matches the requirement of those patients simultaneously suffering from diabetes and gout. We carried out comparative investigations on the proposed test strip and clinical biochemical analyser, which indicates a good agreement and proved the reliability and accuracy of the proposed test strip, as promising solution for the fast growth of family health management market.
School of Electronic Engineering, University of Electronic Science and Technology of China, No. 2006, Xiyuan Ave, Chengdu 611731, China; Paper-fluidic POCT Research and Development Centre, Guizhou LaYa Technology Co. Ltd., Guiyang 550022, China; Microfluidic POCT Research and Development Centre, Sichuan LaYa Micro Technology Co. Ltd., Chengdu 610041, China. Electronic address: guojinhong@uestc.edu.cn.
Jinhong
J
Guo
Sate Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology (Shenzhen), Shenzhen 518055, China. Electronic address: maxing@hitsz.edu.cn.
Xing
X
Ma
D015374:Biosensing Techniques / Q000379:methods*; D001786:Blood Glucose / Q000302:isolation & purification*; D003920:Diabetes Mellitus / Q000097:blood*; D006801:Humans; D008991:Monitoring, Physiologic; D011934:Reagent Strips / Q000737:chemistry; D014527:Uric Acid / Q000097:blood*
D001786:Blood Glucose; D011934:Reagent Strips; D014527:Uric Acid
Dual channel test strip; Electrochemical sensor; Family health management; Glucose sensor; Uric acid sensor