The prevalence, awareness, treatment, and control of dyslipidemia in northeast China: a population-based cross-sectional survey.
BACKGROUND
Dyslipidemia is an important independent modifiable risk factor for cardiovascular disease. The aim of this study was to explore the current prevalence, awareness, treatment and control of dyslipidemia and its associated influence factors in northeast China.


METHODS
In this population-based cross-sectional study, we adopted a multi-stage, stratified sampling method to obtain a representative sample of 4052 permanent residents aged 40 years and over from different urban and rural regions in Dehui City of Jilin Province. All subjects completed a questionnaire and were examined for risk factors. Continuous data were presented as means ± standard deviations (SD) and compared using the Student's t-test. Categorical variables were presented as proportions and compared using the Rao-Scott-χ2test in different subgroups. The associated influence factors for the prevalence, awareness, treatment and control of dyslipidemia were evaluated through multivariate logistic regression.


RESULTS
The prevalence of dyslipidemia was 62.1% overall, with 33.5, 43.9, 0.6, and 8.8% for high total cholesterol, triglyceride, low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol, respectively. Among those with dyslipidemia, the proportion of subjects who were aware, treated, and controlled was 14.4, 33.9, and 19.9%, respectively. Overweight or obesity (OR = 2.156; 95% CI: 1.863, 2.533), hypertension (OR = 1.643; 95% CI: 1.425, 1.893), or diabetes mellitus (OR = 2.173; 95% CI: 1.661, 2.844) increased the prevalence of dyslipidemia, also these participants were more likely to be aware of their condition, however, this did not increase the likelihood of treatment and control. Living in urban areas and higher education level also increased the awareness of dyslipidemia. Personal history of coronary heart disease was the strongest influence factors associated with better awareness, treatment and control of dyslipidemia. Overweight or obesity (OR = 0.404; 95% CI: 0.235, 0.695) and lack of exercise (OR = 0.423; 95% CI: 0.215, 0.830) were associated with poor control of dyslipidemia.


CONCLUSIONS
The prevalence of dyslipidemia among adults aged 40 years and over in northeast China was high, however, the awareness, treatment, and control of dyslipidemia was measured at far from desirable levels. Renewed efforts taking influence factors into account are needed to improve the current unsatisfactory condition.
Stroke Center, Department of Neurology, the First Hospital of Jilin University, Xinmin Street 71#, 130021, Changchun, China.
Fu-Liang
FL
Zhang
Neuroscience Center, Department of Neurology, the First Hospital of Jilin University, Xinmin Street 71#, 130021, Chang Chun, China.
Ying-Qi
YQ
Xing
Division of Clinical Research, the First Hospital of Jilin University, Changchun, China.
Yan-Hua
YH
Wu
Stroke Center, Department of Neurology, the First Hospital of Jilin University, Xinmin Street 71#, 130021, Changchun, China.
Hao-Yuan
HY
Liu
Stroke Center, Department of Neurology, the First Hospital of Jilin University, Xinmin Street 71#, 130021, Changchun, China.
Yun
Y
Luo
Stroke Center, Department of Neurology, the First Hospital of Jilin University, Xinmin Street 71#, 130021, Changchun, China.
Ming-Shuo
MS
Sun
Neuroscience Center, Department of Neurology, the First Hospital of Jilin University, Xinmin Street 71#, 130021, Chang Chun, China. zhen1ni2@163.com.
Zhen-Ni
ZN
Guo
Stroke Center, Department of Neurology, the First Hospital of Jilin University, Xinmin Street 71#, 130021, Changchun, China. doctoryangyi@163.com.
Yi
Y
Yang
D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000503:physiopathology; D050171:Dyslipidemias / Q000097:blood / Q000188:drug therapy* / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009765:Obesity / Q000503:physiopathology; D015995:Prevalence; D062486:Public Health Surveillance; D012307:Risk Factors; D012424:Rural Population; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000097:blood; D014505:Urban Population
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D000960:Hypolipidemic Agents; D014280:Triglycerides
Awareness rate; Control rate; Dyslipidemia; Epidemiology; Northeast China; Prevalence; Treatment rate