Nanomaterials for Tissue Engineering In Dentistry.
The tissue engineering (TE) of dental oral tissue is facing significant changes in clinical treatments in dentistry. TE is based on a stem cell, signaling molecule, and scaffold triad that must be known and calibrated with attention to specific sectors in dentistry. This review article shows a summary of micro- and nanomorphological characteristics of dental tissues, of stem cells available in the oral region, of signaling molecules usable in TE, and of scaffolds available to guide partial or total reconstruction of hard, soft, periodontal, and bone tissues. Some scaffoldless techniques used in TE are also presented. Then actual and future roles of nanotechnologies about TE in dentistry are presented.
Department of Civil and Environmental Engineering-UdR INSTM-University of Perugia, Strada di Pentima, 4-05100 Terni, Italy. manila.chieruzzi@unipg.it.
Manila
M
Chieruzzi
Department of Surgical and Biomedical Sciences-University of Perugia, S. Andrea delle Fratte, 06156 Perugia, Italy. stefanopagano@gmail.com.
Stefano
S
Pagano
Department of Experimental Medicine-University of Perugia Polo Unico Sant'Andrea delle Fratte, 06132 Perugia, Italy. silvia.moretti@unipg.it.
Silvia
S
Moretti
Department of Biomedical Science-University of Sassari viale San Pietro 43/C -07100 Sassari, Italy. rpinna@uniss.it.
Roberto
R
Pinna
Department of Biomedical Science-University of Sassari viale San Pietro 43/C -07100 Sassari, Italy. emilia@uniss.it.
Egle
E
Milia
Department of Civil and Environmental Engineering-UdR INSTM-University of Perugia, Strada di Pentima, 4-05100 Terni, Italy. luigi.torre@unipg.it.
Luigi
L
Torre
Department of Surgical and Biomedical Sciences-University of Perugia, S. Andrea delle Fratte, 06156 Perugia, Italy. stefano.eramo@unipg.it.
Stefano
S
Eramo
dentistry; nanomaterials tissue engineering; scaffolds; signalling molecules; stem cells