Concordance of Penile and Oral Human Papillomavirus Infections Among Men in the United States.
This study examined the concordance of penile and oral human papillomavirus (HPV) infections in the United States. A total of 1683 men aged 18-59 years who participated in the 2013-2014 National Health and Nutrition Examination Survey and had results of oral and penile HPV DNA testing were examined. The prevalence of any HPV genotype was 45.3% on the penis, 11.2% in the oral cavity, and 8.8% at both sites. The prevalence of HPV in the oral cavity was higher among those with than among those without penile HPV infection (19.3% vs 4.4%; prevalence ratio, 4.37 [95% confidence interval, 2.66-7.16]). The prevalence of ≥1 genotype-concordant HPV infection was 3.2% and was associated with sexual behavior, independent of demographic characteristics and smoking status. Sexual behavior may partly explain the observed association between penile and oral HPV infections.
Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
Eshan U
EU
Patel
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Anne F
AF
Rositch
Department of Global Health, George Washington University, Washington, District of Columbia.
Patti E
PE
Gravitt
Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
Aaron A R
AAR
Tobian
D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D004279:DNA, Viral / Q000302:isolation & purification; D005838:Genotype; D061809:Human Papillomavirus DNA Tests; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009055:Mouth / Q000821:virology*; D015999:Multivariate Analysis; D009749:Nutrition Surveys; D027383:Papillomaviridae / Q000235:genetics; D030361:Papillomavirus Infections / Q000453:epidemiology*; D010413:Penis / Q000821:virology*; D012044:Regression Analysis; D012307:Risk Factors; D057566:Self Report; D012725:Sexual Behavior; D014481:United States / Q000453:epidemiology; D055815:Young Adult
D004279:DNA, Viral
HPV; NHANES; concordance.; genotype; human papillomavirus; oral; penile