Low-Dose Naltrexone: A New Therapy Option for Complex Regional Pain Syndrome Type I Patients.
Naltrexone (an opioid antagonist) has long been used in patients overcoming alcohol and opioid dependency. However, at doses one-tenth of those commonly prescribed for the above conditions, an unexpected effect occurs that aids in alleviating pain. Although there are currently no randomized clinical trials supporting the use of low-dose naltrexone, we present a case study describing the impact of compounding low-dose naltrexone that has dramatically improved the patient's pain symptoms which were refractory to other treatments.
Midwestern University-Chicago College of Pharmacy, Downers Grove, Illinois.
Kayla M
KM
Sturn
Healthway Compounding Pharmacy, Saginaw, Michigan. mcollins@healthwayrx.com.
Michael
M
Collin
D000293:Adolescent; D005260:Female; D006801:Humans; D009271:Naltrexone / Q000009:adverse effects / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000627:therapeutic use*; D012019:Reflex Sympathetic Dystrophy / Q000188:drug therapy*
D009292:Narcotic Antagonists; D009271:Naltrexone