Behavioural and neuropsychiatric disturbance in three clinical subtypes of frontotemporal dementia: A Clinical Research Center for Dementia of South Korea-FTD Study.
OBJECTIVE
To characterise the behavioural and neuropsychiatric disturbances of patients with three clinical subtypes of frontotemporal dementia (FTD): behavioural variant FTD (bvFTD), semantic dementia (SD) and progressive non-fluent aphasia (PNFA).


METHODS
Consecutive series of 66 patients with bvFTD, 58 patients with SD and 21 patients with PNFA were compared using the Frontal Behavioural Inventory (FBI) and the Neuropsychiatric Inventory (NPI).


RESULTS
Patients with bvFTD had more behavioural and neuropsychiatric disturbances than patients with PNFA based on the total scores of FBI and NPI. When comparing subtotal and item scores of FBI and NPI, there were some significant differences among three clinical subtypes of FTD.


CONCLUSIONS
There are some distinct patterns of behavioural and neuropsychiatric disturbance among three clinical subtypes of FTD.
Department of Neurology, Korea University College of Medicine and Korea University Ansan Hospital, Ansan, Korea.
Moon Ho
MH
Park
Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Busan, Korea.
Eun-Joo
EJ
Kim
Department of Neurology, Dong-A Medical Center, Dong-A University College of Medicine, Busan, Korea.
Kyung Won
KW
Park
Department of Neurology, Changwon Fatima Hospital, Changwon, Korea.
Jae Cheol
JC
Kwon
Department of Neurology, Catholic Kwandong University College of Medicine, Gangneung, Korea.
Bon D
BD
Ku
Department of Neurology, Konkuk University Medical Center and Konkuk University School of Medicine, Seoul, Korea.
Seol-Heui
SH
Han
Department of Neurology, Seoul National University College of Medicine and Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seoul, Korea.
SangYun
S
Kim
Department of Neurology, The Catholic University of Korea College of Medicine, Seoul, Korea.
Dong Won
DW
Yang
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Duk L
DL
Na
Department of Neurology, Inha University School of Medicine, Incheon, Korea.
Seong Hye
SH
Choi
D000368:Aged; D005260:Female; D057180:Frontotemporal Dementia / Q000145:classification / Q000175:diagnosis* / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D057178:Primary Progressive Nonfluent Aphasia / Q000145:classification / Q000175:diagnosis* / Q000523:psychology*; D012042:Registries; D056910:Republic of Korea; D012189:Retrospective Studies
behavioural symptoms; brief psychiatric rating scale; frontotemporal dementia